Published March 25, 2024
| Version 0.0.1
Dataset
Open
Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms
Authors/Creators
- 1. Centre Hospitalier Universitaire Vaudois
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2.
University of Lausanne
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3.
University Hospital of Lausanne
Description
Single-cell RNA (scRNA) and single-cell TCR (scTCR)-sequencing data data for patients number 11, 12 and 14 from the article " Identification of clinically relevant T-cell receptors for personlized T-cell therapy".
Each compressed file contains two subfolders. One is for the scRNA-seq (GEX-sequencing) and the other for the scTCR-seq (VDJ-sequencing).
In the original article, scRNA-seq and scTCR-seq were aligned to the GRCh38 reference genome using cellranger count (10X Genomics, version 3.0.1) and vdj (10X Genomics, version 3.1.0) respectively. The subsequent data processing was performed using Seurat library (V.4.3.0) on R Statistical Software (V.4.0.3).