Group abundances of UniRef50 gene families obtained with HUMAnN2 to Gene Ontology (GO) slim terms with relative abundances: release v1.2.0

HUMAnN2 is a pipeline to profile the presence/absence and abundance of microbial pathways in community of microbiota sequencing data. One output is a file with UniRef50 gene family abundances. HUMAnN2 proposes a script to regroup Uniref50 to GO, but used GO terms are too precise to get a broad overview of the ontology content.

The tool developed here contains scripts to group UniRef50 abundances obtained using main HUMANn2 script (Gene families) to GO slim terms. GO slim is a subset of the terms in the whole GO. For this tool, metagenomics GO slim terms developed by Jane Lomax and the InterPro group.

This release can be used by itself, but it is also associated with a wrapper for Galaxy. This wrapper is currently available on Galaxy Test ToolShed under name group_humann2_uniref_abundances_to_go, with owner bebatut.

This tool comes also with a conda package.