Published July 31, 2014 | Version v1.0
Dataset Open

Multi-state modeling of the PhoQ two-component system

Creators

  • 1. Biochemistry and Molecular Biophysics Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute University of California, San Francisco, CA 94158, USA
  • 2. Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biosciences
  • 3. Pharmacological Sciences Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA
  • 4. Centyrex, Janssen Research & Development LLC, Spring House, PA 19002, USA
  • 5. Department of Physics, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
  • 6. Department of Pharmaceutical Chemistry, Cardiovascular Research Institute University of California, San Francisco, CA 94158, USA

Contributors

Data manager:

  • 1. University of California San Francisco

Description

This directory contains the input data, protocols and output model for the modeling of the PhoQ homodimer, using cysteine crosslinking and multi-state Bayesian modeling in IMP.

For more information about how to reproduce this modeling, see https://salilab.org/phoq or the README file.

Files

phoq-v1.0.zip

Files (23.6 MB)

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Additional details

Related works

Is supplement to
https://github.com/integrativemodeling/phoq/tree/v1.0 (URL)
10.1016/j.str.2014.04.019 (DOI)
https://salilab.org/phoq (URL)