Published December 12, 2014 | Version v1
Dataset Open

Multiple Sclerosis: Cerebral Circulation Time is prolonged and not correlated with expanded disability status scale (EDSS). A study using digital subtracted angiography

  • 1. Unit of Neuroimaging and Neurointervention, Department of Neurological and Sensorial Sciences Azienda Ospedaliera Universitaria Senese, Santa Maria alle Scotte General Hospital, Siena, Italy
  • 2. Dept. of Medicine, Surgery & Neuroscience, University of Siena, Siena, Italy
  • 3. Dept. of Neurology, General Hospital of “S. Donato d’Arezzo”, Italy
  • 4. Unit of Nuclear Medicine, Azienda Ospedaliera Universitaria Senese, Santa Maria alle Scotte General Hospital, Siena, Italy
  • 5. Unit of Endovascular and Percutaneous Therapy, Clinica Nuestra Senora del Rosario, Madrid, Spain
  • 6. Dept. Life Sciences, University of Siena (Italy)
  • 7. Berenson-Allen Center for Non-Invasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Description

Dataset used to study the relationship between cerebral circulation time (CCT) and some clinical evidences, e.g. expand disability status scale (EDSS), disease duration, age at onset,... CCT was measured through the digital subtraction angiography (DSA) technique. 

Statistical Parametric Mapping software (SPM, Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London; http://www.fil.ion.ucl.ac.uk/spm/) and ad-hoc scripts developed in the MATLAB scientific computing environment (http://www.mathworks.com, MathWorks, MA, USA) were applied to valuate the lesion volume and brain volume in MS patients.

Notes

The data included in the xlsx format are organized in two sheets: the first sheet contains CCT values by group (MS patients and Controls) and clinical data from the MS patients (EDSS, age at onset, therapy,...). The second sheet reports the values of lesion volume and brain volumes measured in a subset of MS patients.

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