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Published August 31, 2023 | Version v1
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Exploring the epidemiological role of the Eurasian lynx (Lynx lynx) in the life cycle of Toxoplasma gondii

  • 1. Institute for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty University of Bern, L¨anggassstrasse 122, 3012, Bern, & Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty University of Bern, L¨anggassstrasse 122, 3012, Bern, Switzerland
  • 2. Institute for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty University of Bern, L¨anggassstrasse 122, 3012, Bern,
  • 3. Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty University of Bern, L¨anggassstrasse 122, 3012, Bern, Switzerland
  • 4. PathoVet AG, Buckstrasse 2, 8317, Tagelswangen, Switzerland

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Scherrer, Patrick, Ryser-Degiorgis, Marie-Pierre, Marti, Iris A., St, Borel, ephanie, Frey, Caroline F., Mueller, Norbert, Ruetten, Maja, Basso, Walter (2023): Exploring the epidemiological role of the Eurasian lynx (Lynx lynx) in the life cycle of Toxoplasma gondii. International Journal for Parasitology: Parasites and Wildlife 21: 1-10, DOI: 10.1016/j.ijppaw.2023.03.005, URL: http://dx.doi.org/10.1016/j.ijppaw.2023.03.005

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References

  • Allen, K.E., Yabsley, M.J., Johnson, E.M., Reichard, M.V., Panciera, R.J., Ewing, S.A., Little, S.E., 2011. Novel Hepatozoon in vertebrates from the southern United States. J. Parasitol. 97, 648-653.
  • Anderson, D.R., Link, W.A., Johnson, D.H., Burnham, K.P., 2001. Suggestions for presenting the results of data analyses. J. Wildl. Manag. 65, 373.
  • Basso, W., Edelhofer, R., Zenker, W., M¨ostl, K., Kubber-Heiss, A., Prosl, H., 2005. Toxoplasmosis in Pallas' cats (Otocolobus manul) raised in captivity. Parasitology 130, 293-299.
  • Basso, W., Alvarez Rojas, C.A., Buob, D., Ruetten, M., Deplazes, P., 2020a. Sarcocystis infection in red deer (Cervus elaphus) with eosinophilic myositis/fasciitis in Switzerland and involvement of red foxes (Vulpes vulpes) and hunting dogs in the transmission. Int. J. Parasitol. Parasites Wildl. 13, 130-141.
  • Zanolari, P., 2020b. Toxoplasma gondii and Neospora caninum infections in South American camelids in Switzerland and assessment of serological tests for diagnosis. Parasites Vectors 13, 256.
  • Basso, W., Holenweger, F., Schares, G., Muller, N., Campero, L.M., Arduser, F., Moore-Jones, G., Frey, C.F., Zanolari, P., 2022. Toxoplasma gondii and Neospora caninum infections in sheep and goats in Switzerland: seroprevalence and occurrence in aborted foetuses. Food Waterborne Parasitol 28, e00176.
  • Berger-Schoch, A.E., Herrmann, D.C., Schares, G., Muller, N., Bernet, D., Gottstein, B., Frey, C.F., 2011. Prevalence and genotypes of Toxoplasma gondii in feline faeces (oocysts) and meat from sheep, cattle and pigs in Switzerland. Vet. Parasitol. 177, 290-297.
  • Boothroyd, J.C., Grigg, M.E., 2002. Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease? Curr. Opin. Microbiol. 5, 438-442.
  • Breitenmoser, U., Breitenmoser-Wursten, C., 2008. Der Luchs: Ein Grossraubtier in der Kulturlandschaft. Salm, Wohlen/Bern.
  • Breitenmoser-Wursten, C., Vandel, J.-M., Zimmermann, F., Breitenmoser, U., 2007. Demography of lynx (Lynx lynx) in the Jura mountains. Wildl. Biol. 13, 381-392.
  • Castro, B.B.P., Gennari, S.M., Lorenzi, H., Su, C., 2020. A simple method to generate PCR-RFLP typing profiles from DNA sequences in Toxoplasma gondii. Infect. Genet. Evol. 85, 104590.
  • Conrady, C.D., Besirli, C.G., Baumal, C.R., Kovach, J.L., Etzel, J.D., Tsui, J.C., Elner, S.G., Johnson, M.W., 2022. Ocular toxoplasmosis after exposure to wild game. Ocul. Immunol. Inflamm. 30, 527-532.
  • Crotta, M., Pellicioli, L., Gaffuri, A., Trogu, T., Formenti, N., Tranquillo, V., Luzzago, C., Ferrari, N., Lanfranchi, P., 2022. Analysis of seroprevalence data on Hepatitis E virus and Toxoplasma gondii in wild ungulates for the assessment of human exposure to zoonotic meat-borne pathogens. Food Microbiol. 101, 103890.
  • Deiro ´, A.G.d.J., do Prado, D.P., Sousa, I.P., Rocha, D.d.S., Bezerra, R.A., Gaiotto, F.A., Albuquerque, G.R., Munhoz, A.D., 2021. Presence of atypical genotypes of Toxoplasma gondii isolated from cats in the state of Bahia, Northeast of Brazil. PLoS One 16, e0253630.
  • Deplazes, P., Samson-Himmelstjerna, G., von Zahner, H., Joachim, A., Mathis, A., Taubert, A., Strube, C., 2020. Parasitologie fur die Tiermedizin, fourth ed. Thieme, Stuttgart.
  • Dubey, J.P., 2006. Comparative infectivity of oocysts and bradyzoites of Toxoplasma gondii for intermediate (mice) and definitive (cats) hosts. Vet. Parasitol. 140, 69-75.
  • Dubey, J.P., 2022. Toxoplasmosis of Animals and Humans. CRC Press, Boca Raton, London, New York.
  • Dubey, J.P., Quinn, W.J., Weinandy, D., 1987. Fatal neonatal toxoplasmosis in a bobcat (Lynx rufus). J. Wildl. Dis. 23, 324-327.
  • Won, K., Bishop, H., Punkosdy, G., Sreekumar, C., Vianna, M.C.B., Shen, S.K., Kwok, O.C.H., Sumners, J.A., Demarais, S., Humphreys, J.G., Lehmann, T., 2004. Molecular and biologic characteristics of Toxoplasma gondii isolates from wildlife in the United States. J. Parasitol. 90, 67-71.
  • Dubey, J.P., Verma, S.K., Calero-Bernal, R., Cassinelli, A.B., Kwok, O.C.H., van Why, K., Su, C., Humphreys, J.G., 2015. Isolation and genetic characterization of Toxoplasma gondii from black bears (Ursus americanus), bobcats (Lynx rufus), and feral cats (Felis catus) from Pennsylvania. J. Eukaryot. Microbiol. 62, 410-415.
  • Dubey, J.P., Murata, F.H.A., Cerqueira-C´ezar, C.K., Kwok, O.C.H., 2021a. Epidemiologic and public health significance of Toxoplasma gondii infections in venison: 2009-2020. J. Parasitol. 107, 309-319.
  • Dubey, J.P., Murata, F.H.A., Cerqueira-C´ezar, C.K., Kwok, O.C.H., Su, C., 2021b. Epidemiological significance of Toxoplasma gondii Infections in wild rodents: 2009- 2020. J. Parasitol. 107, 182-204.
  • Elbez-Rubinstein, A., Ajzenberg, D., Dard´e, M.-L., Cohen, R., Dum`etre, A., Yera, H., Gondon, E., Janaud, J.-C., Thulliez, P., 2009. Congenital toxoplasmosis and reinfection during pregnancy: case report, strain characterization, experimental model of reinfection, and review. J. Infect. Dis. 199, 280-285.
  • Fanelli, A., Battisti, E., Zanet, S., Trisciuoglio, A., Ferroglio, E., 2021. A systematic review and meta-analysis of Toxoplasma gondii in roe deer (Capreolus capreolus) and red deer (Cervus elaphus) in Europe. Zoonoses Public Health 68, 182-193.
  • Fern´andez-Escobar, M., Calero-Bernal, R., Benavides, J., Regidor-Cerrillo, J., GuerreroMolina, M.C., Guti´errez-Exp´osito, D., Collantes-Fern´andez, E., Ortega-Mora, L.M., 2020. Isolation and genetic characterization of Toxoplasma gondii in Spanish sheep flocks. Parasites Vectors 13, 396.
  • Fern´andez-Escobar, M., Giorda, F., Mattioda, V., Audino, T., Di Nocera, F., Lucifora, G., Varello, K., Grattarola, C., Ortega-Mora, L.M., Casalone, C., Calero-Bernal, R., 2022a. Toxoplasma gondii genetic diversity in Mediterranean dolphins. Pathogens 11.
  • Fernandez-Escobar ´, M., Schares, G., Maksimov, P., Joeres, M., Ortega-Mora, L.M., Calero-Bernal, R., 2022b. Toxoplasma gondii genotyping: a closer look into Europe. Front. Cell. Infect. Microbiol. 12, 842595.
  • Gaffuri, A., Giacometti, M., Tranquillo, V.M., Magnino, S., Cordioli, P., Lanfranchi, P., 2006. Serosurvey of roe deer, chamois and domestic sheep in the central Italian Alps. J. Wildl. Dis. 42, 685-690.
  • Garcia-Bocanegra, I., Dubey, J.P., Martinez, F., Vargas, A., Cabez´on, O., Zorrilla, I., Arenas, A., Almeria, S., 2010. Factors affecting seroprevalence of Toxoplasma gondii in the endangered Iberian lynx (Lynx pardinus). Vet. Parasitol. 167, 36-42.
  • Gotteland, C., Aubert, D., Gibert, P., Moinet, M., Klein, F., Game, Y., Villena, I., GilotFromont, E., 2014. Toxoplasmosis in natural populations of ungulates in France: prevalence and spatiotemporal variations. Vector Borne Zoonotic Dis. 14, 403-413.
  • Grigg, M.E., Ganatra, J., Boothroyd, J.C., Margolis, T.P., 2001. Unusual abundance of atypical strains associated with human ocular toxoplasmosis. J. Infect. Dis. 184, 633-639.
  • Guerina, N.G., 1994. Congenital infection with Toxoplasma gondii. Pediatr. Ann. 23 (138-42), 147-151.
  • Herrmann, D.C., Wibbelt, G., Gotz ¨, M., Conraths, F.J., Schares, G., 2013. Genetic characterisation of Toxoplasma gondii isolates from European beavers (Castor fiber) and European wildcats (Felis silvestris silvestris). Vet. Parasitol. 191, 108-111.
  • Hill, D.E., Dubey, J.P., Abbott, R.C., van Riper, C., Enright, E.A., 2014. Toxoplasmosis. U. S. Geological Survey Circular, p. 1389.
  • Hodˇzi´c, A., Ali´c, A., Praˇsovi´c, S., Otranto, D., Baneth, G., Duscher, G.G., 2017. Hepatozoon silvestris sp. nov.: morphological and molecular characterization of a new species of Hepatozoon (Adeleorina: hepatozoidae) from the European wild cat (Felis silvestris silvestris). Parasitology 144, 650-661.
  • Homan, W., Vercammen, M., Braekeleer, J. de, Verschueren, H., 2000. Identification of a 200- to 300-fold repetitive 529 bp DNA fragment in Toxoplasma gondii, and its use for diagnostic and quantitative PCR. Int. J. Parasitol. 30, 69-75.
  • Jokelainen, P., 2012. Endemic Toxoplasma gondii genotype II causes fatal infections in animal hosts in Europe - lessons learnt. In: Djurkovic ´Djakovi´c, O. (Ed.), Toxoplasmosis - Recent Advances. IntechOpen.
  • Sukura, A., 2013. Free-ranging eurasian lynx (Lynx lynx) as host of Toxoplasma gondii in Finland. J. Wildl. Dis. 49, 527-534.
  • Kegler, K., Nufer, U., Alic, A., Posthaus, H., Olias, P., Basso, W., 2018. Fatal infection with emerging apicomplexan parasite Hepatozoon silvestris in a domestic cat. Parasites Vectors 11, 428.
  • Kenny, D.E., Lappin, M.R., Knightly, F., Baier, J., Brewer, M., Getzy, D.M., 2002. Toxoplasmosis in pallas' cats (Otocolobus felis manul) at the denver zoological gardens. J. Zoo Wildl. Med. 33, 131-138.
  • Kohn, M.A., Senjak, J., 2021. Sample Size Calculators (Website). UCSF CTSI. 20 December 2021. Available at: https://www.sample-size.net/. (Accessed 30 November 2022).
  • Labelle, P., Dubey, J.P., Mikaelian, I., Blanchette, N., Lafond, R., St-Onge, S., Martineau, D., 2001. Seroprevalence of antibodies to Toxoplasma gondii in lynx (Lynx canadensis) and bobcats (Lynx rufus) from Qu´ebec, Canada. J. Parasitol. 87, 1194.
  • Landis, J.R., Koch, G.G., 1977. The measurement of observer agreement for categorical data. Biometrics 33, 159-174.
  • Lukeˇsov´a, D., Liter´ak, I., 1998. Shedding of Toxoplasma gondii oocysts by felidae in zoos in the Czech republic. Vet. Parasitol. 74, 1-7.
  • Marchiondo, A.A., 1976. Prevalence of antibodies to Toxoplasma gondii in wild and domestic animals of New Mexico, Arizona and Colorado. J. Wildl. Dis. 226-232.
  • Marreros, N., Hussy, D., Albini, S., Frey, C.F., Abril, C., Vogt, H.-R., Holzwarth, N., WirzDittus, S., Friess, M., Engels, M., Borel, N., Willisch, C.S., Signer, C., Hoelzle, L.E., Ryser-Degiorgis, M.-P., 2011. Epizootiologic investigations of selected abortive agents in free-ranging Alpine ibex (Capra ibex ibex) in Switzerland. J. Wildl. Dis. 47, 530-543.
  • Marti, I., Ryser-Degiorgis, M.-P., 2018a. A tooth wear scoring scheme for age estimation of the Eurasian lynx (Lynx lynx) under field conditions. Eur. J. Wildl. Res. 64.
  • Marti, I., Ryser-Degiorgis, M.-P., 2018b. Morphometric characteristics of free-ranging Eurasian lynx (Lynx lynx) in Switzerland and their suitability for age estimation. Wildl. Biol. 1-10.
  • Mercer, S.H., Jones, L.P., Rappole, J.H., Twedt, D., Lack, L.L., Craig, T.M., 1988. Hepatozoon sp. in wild carnivores in Texas. J. Wildl. Dis. 24, 574-576.
  • Metzger, B., dos Santos Paduan, K., Rubini, A.S., Oliveira, T.G. de, Pereira, C., O' Dwyer, L.H., 2008. The first report of Hepatozoon sp. (Apicomplexa: hepatozoidae) in neotropical felids from Brazil. Vet. Parasitol. 152, 28-33.
  • Miller, N.L., 1972. Oral Infections with Toxoplasma cysts and oocysts in felines, other mammals, and in birds. J. Parasitol. 928-937.
  • Molinari-Jobin, A., Zimmermann, F., Ryser, A., Breitenmoser-Wursten, C., Capt, S., Breitenmoser, U., Molinari, P., Haller, H., Eyholzer, R., 2007. Variation in diet, prey selectivity and home-range size of Eurasian lynx (Lynx lynx) in Switzerland. Wildl. Biol. 13, 393-405.
  • Morend, F., Lang, J., Vidondo, B., Ryser-Degiorgis, M.-P., 2022. Radiographic pelvimetry in free-ranging Eurasian lynx (Lynx lynx carpathicus) from Switzerland. Eur. J. Wildl. Res. 68.
  • Mucker, E.M., Dubey, J.P., Lovallo, M.J., Humphreys, J.G., 2006. Seroprevalence of antibodies to Toxoplasma gondii in the Pennsylvania bobcat (Lynx rufus rufus). J. Wildl. Dis. 42, 188-191.
  • Muller, N., Zimmermann, V., Forster, U., Bienz, M., Gottstein, B., Welle, M., 2003. PCRbased detection of canine Leishmania infections in formalin-fixed and paraffin-embedded skin biopsies: elaboration of a protocol for quality assessment of the diagnostic amplification reaction. Vet. Parasitol. 114, 223-229.
  • Muller, N., Hentrich, B., Frey, C.F., Welle, M., 2015. Quantitative PCR for the diagnosis of cutaneous leishmaniasis from formalin-fixed and paraffin-embedded skin sections. Mol. Cell. Probes 29, 507-510.
  • Oksanen, A., Asbakk, K., Nieminen, M., Norberg, H., N¨areaho, A., 1997. Antibodies against Toxoplasma gondii in Fennoscandian reindeer - association with the degree of domestication. Parasitol. Int. 46, 255-261.
  • Ortega-Mora, L., Gottstein, B., Conraths, F.J., Buxton, D. (Eds.), 2007. Protozoal Abortion in Farm Ruminants: Guidelines for Diagnosis and Control. CABI, Wallingford, Oxfordshire, UK, Cambridge, MA.
  • Pardo Gil, M., Hegglin, D., Briner, T., Ruetten, M., Muller, N., More, G., Frey, C.F., Deplazes, P., Basso, W., 2023. High prevalence rates of Toxoplasma gondii in cathunted small mammals - evidence for parasite induced behavioural manipulation in the natural environment? Int. J. Parasitol. Parasites Wildl. https://doi.org/10.1016/ j.ijppaw.2023.01.007.
  • Pomares, C., Ajzenberg, D., Bornard, L., Bernardin, G., Hasseine, L., Darde, M.-L., Marty, P., 2011. Toxoplasmosis and horse meat, France. Emerg. Infect. Dis. 17, 1327-1328.
  • Porter, S.B., Sande, M.A., 1992. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N. Engl. J. Med. 327, 1643-1648.
  • Prestrud, K.W., Asbakk, K., Mork, T., Fuglei, E., Tryland, M., Su, C., 2008. Direct highresolution genotyping of Toxoplasma gondii in arctic foxes (Vulpes lagopus) in the remote arctic Svalbard archipelago reveals widespread clonal type II lineage. Vet. Parasitol. 158, 121-128.
  • R Core Team, 2021. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/.
  • Reischl, U., Bretagne, S., Krueger, D., Ernault, P., Costa, J.-M., 2003. Comparison of two DNA targets for the diagnosis of T. gondii by real-time PCR. BMC Infect. Dis. 7.
  • Riemann, H.P., Fowler, M.E., Schulz, T., Lock, A., Thilsted, J., Pulley, L.T., Hendrickson, R.V., Henness, A.M., Franti, C.E., Behymer, D.E., 1974. Toxoplasmosis in pallas cats. J. Wildl. Dis. 10, 471-477.
  • Roelke, M.E., Johnson, W.E., Mill´an, J., Palomares, F., Revilla, E., Rodriguez, A., Calzada, J., Ferreras, P., Le´on-Vizcaino, L., Delibes, M., O' Brien, S.J., 2008. Exposure to disease agents in the endangered Iberian lynx (Lynx pardinus). Eur. J. Wildl. Res. 54, 171-178.
  • Ryser-Degiorgis, M.-P., Segner, H., 2015. National competence center for wildlife diseases in Switzerland: mandate, development and current strategies. Schweiz. Arch. Tierheilkd. 157, 255-266.
  • Ryser-Degiorgis, M.-P., Jakubek, E.-B., Segerstad, C.H. af, Br¨ojer, C., Morner ¨, T., Jansson, D.S., Lund´en, A., Uggla, A., 2006. Serological survey of Toxoplasma gondii infection in free-ranging Eurasian lynx (Lynx lynx) from Sweden. J. Wildl. Dis. 42, 182-187.
  • Ryser-Degiorgis, M.-P., Meli, M.L., Breitenmoser-Wuersten, C., Hofmann-Lehmann, R., Marti, I., Pisano, S.R.R., Breitenmoser, U., 2021. Health surveillance in wild felid conservation - experiences with the Eurasian lynx in Switzerland. CATnews Special Issue 14, 64-75.
  • Schares, G., Herrmann, D.C., Beckert, A., Schares, S., Hosseininejad, M., Pantchev, N., Globokar Vrhovec, M., Conraths, F.J., 2008. Characterization of a repetitive DNA fragment in Hammondia hammondi and its utility for the specific differentiation of H. hammondi from Toxoplasma gondii by PCR. Mol. Cell. Probes 22, 244-251.
  • Schreiber, N., Basso, W., Riond, B., Willi, B., Torgerson, P.R., Deplazes, P., 2021. Antibody kinetics and exposure to Toxoplasma gondii in cats: a seroepidemiological study. Int. J. Parasitol. 51, 291-299.
  • Shwab, E.K., Zhu, X.-Q., Majumdar, D., Pena, H.F.J., Gennari, S.M., Dubey, J.P., Su, C., 2014. Geographical patterns of Toxoplasma gondii genetic diversity revealed by multilocus PCR-RFLP genotyping. Parasitology 141, 453-461.
  • Sibley, L.D., Boothroyd, J.C., 1992. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 359, 82-85.
  • Spycher, A., Geigy, C., Howard, J., Posthaus, H., Gendron, K., Gottstein, B., Debache, K., Herrmann, D.C., Schares, G., Frey, C.F., 2011. Isolation and genotyping of Toxoplasma gondii causing fatal systemic toxoplasmosis in an immunocompetent 10- year-old cat. J. Vet. Diagn. Invest. 23, 104-108.
  • Su, C., Dubey, J.P., 2020. Isolation and genotyping of Toxoplasma gondii strains. In: Tonkin, C. (Ed.), Toxoplasma gondii. Methods in Molecular Biology, vol. 2071 (New York, NY).
  • Verma, S.K., Sweeny, A.R., Lovallo, M.J., Calero-Bernal, R., Kwok, O.C., Jiang, T., Su, C., Grigg, M.E., Dubey, J.P., 2017. Seroprevalence, isolation and co-infection of multiple Toxoplasma gondii strains in individual bobcats (Lynx rufus) from Mississippi, USA. Int. J. Parasitol. 47, 297-303.
  • Vincze, T., Posfai, J., Roberts, R.J., 2003. NEBcutter: a program to cleave DNA with restriction enzymes. Nucleic Acids Res. 31, 3688-3691.
  • Vitaliano, S.N., Soares, H.S., Minervino, A.H.H., Santos, A.L.Q., Werther, K., Marvulo, M. F.V., Siqueira, D.B., Pena, H.F.J., Soares, R.M., Su, C., Gennari, S.M., 2014. Genetic characterization of Toxoplasma gondii from Brazilian wildlife revealed abundant new genotypes. Int. J. Parasitol. Parasites Wildl. 3, 276-283.
  • Wendte, J.M., Gibson, A.K., Grigg, M.E., 2011. Population genetics of Toxoplasma gondii: new perspectives from parasite genotypes in wildlife. Vet. Parasitol. 182, 96-111.
  • Winzer, P., Muller, J., Aguado-Martinez, A., Rahman, M., Balmer, V., Manser, V., Ortega-Mora, L.M., Ojo, K.K., Fan, E., Maly, D.J., van Voorhis, W.C., Hemphill, A., 2015. In vitro and in vivo effects of the bumped kinase inhibitor 1294 in the related cystforming Apicomplexans Toxoplasma gondii and Neospora caninum. Antimichrob. Agents Chemother. 59, 6361-6374.
  • Witter, R., Pena, H.F.J., Maia, M.O., Magalhtaes, A.O. de, Morgado, T.O., Colodel, E.M., Barros, D.A., Igarashi, M., Gennari, S.M., Pacheco, R.C., 2020. Isolation and genotyping of Toxoplasma gondii in the Midwestern Brazil revealed high genetic diversity and new genotypes. Acta Trop. 212, 105681.
  • Yu, L., Shen, J., Su, C., Sundermann, C.A., 2013. Genetic characterization of Toxoplasma gondii in wildlife from Alabama, USA. Parasitol. Res. 112, 1333-1336.
  • Zarnke, R.L., Dubey, J.P., Ver Hoef, J.M., McNay, M.E., Kwok, O.C., 2001. Serologic survey for Toxoplasma gondii in lynx from interior Alaska. J. Wildl. Dis. 37, 36-38.
  • Zulpo, D.L., Sammi, A.S., Dos Santos, J.R., Sasse, J.P., Martins, T.A., Minutti, A.F., Cardim, S.T., Barros, L.D. de, Navarro, I.T., Garcia, J.L., 2018. Toxoplasma gondii: a study of oocyst re-shedding in domestic cats. Vet. Parasitol. 249, 17-20.