An Update on Zollinger-Ellison Syndrome

Abstract:

Zollinger-Ellison syndrome is a rare disease, characterized by the presence of acid hypersecretion, gastric-duodenal ulcer disease, and a gastrin-secreting pancreatic or extrapancreatic tumor with difficult primary location. The therapy is initially long-term medical to reduce exposure to acid (high-dose proton pump inhibitors) and surgical treatment. The present article highlights the etiology, pathophysiology, diagnosis, treatment and prognosis of Zollinger-Ellison syndrome