include,Reviewer,search_term,transcript_id,gene_id,sprot_geneName_BlastX,sprot_geneFunction_BlastX,sprot_geneName_BlastP,sprot_geneFunction_BlastP,GO_BlastX_1,GO_BlastX_2,GO_BlastX_3,GO_BlastX_4,GO_BlastX_5,GO_BlastP_1,GO_BlastP_2,GO_BlastP_3,GO_BlastP_4,GO_BlastP_5,Kegg,eggnog,Pfam_1,Pfam_2,Pfam_3,Pfam_4,Pfam_5,,
no,AD,ADAMTS,DN8507_c0_g1_i4,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^83-126^E:6.6e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^428-451^E:9.5e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^489-511^E:0.00016,PF00090.19^TSP_1^Thrombospondin type 1 domain^574-628^E:1.5e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^656-706^E:0.037,,
no,AD,ADAMTS,DN8507_c0_g1_i6,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^84-127^E:4.8e-06,NA,NA,NA,NA,,
no,AD,ADAMTS,DN8507_c0_g1_i2,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^83-126^E:7.6e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^428-451^E:0.00011,PF00090.19^TSP_1^Thrombospondin type 1 domain^489-511^E:0.00018,PF00090.19^TSP_1^Thrombospondin type 1 domain^574-628^E:1.8e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^656-706^E:0.043,,
no,AD,ADAMTS,DN8507_c0_g1_i10,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^82-125^E:4.7e-06,NA,NA,NA,NA,,
no,AD,ADAMTS,DN8507_c0_g1_i5,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,.,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN8507_c0_g1_i12,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^83-126^E:4.7e-06,NA,NA,NA,NA,,
no,AD,ADAMTS,DN8507_c0_g1_i3,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^83-126^E:7.8e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^428-451^E:0.00011,PF00090.19^TSP_1^Thrombospondin type 1 domain^489-511^E:0.00018,PF00090.19^TSP_1^Thrombospondin type 1 domain^574-628^E:1.8e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^656-706^E:0.044,,
no,AD,ADAMTS,DN8507_c0_g1_i8,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^223-246^E:7.9e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^284-306^E:0.00013,PF00090.19^TSP_1^Thrombospondin type 1 domain^369-423^E:1.3e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^451-501^E:0.031,PF00090.19^TSP_1^Thrombospondin type 1 domain^507-557^E:8e-07,,
no,AD,ADAMTS,DN8507_c0_g1_i9,DN8507_c0_g1,ATL3_HUMAN,ADAMTS-like protein 3,ATL3_HUMAN,ADAMTS-like protein 3,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:57188,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^83-126^E:4.7e-06,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i2,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,.,NA,NA,NA,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",.,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i13,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,.,NA,NA,NA,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",.,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i16,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,ATL5_HUMAN,ADAMTS-like protein 5,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^2-70^E:5.7e-17,PF01759.21^NTR^UNC-6/NTR/C345C module^144-243^E:1.1e-15,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i8,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,.,NA,NA,NA,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",.,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i5,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,ATL5_HUMAN,ADAMTS-like protein 5,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",PF00090.19^TSP_1^Thrombospondin type 1 domain^134-181^E:3.7e-10,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i3,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,ATL5_HUMAN,ADAMTS-like protein 5,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",PF00090.19^TSP_1^Thrombospondin type 1 domain^134-181^E:3.9e-10,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i10,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,.,NA,NA,NA,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",.,NA,NA,NA,NA,,
yes,AD,ADAMTS,DN5266_c0_g1_i18,DN5266_c0_g1,ATL5_HUMAN,ADAMTS-like protein 5,ATL5_HUMAN,ADAMTS-like protein 5,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0001527^cellular_component^microfibril,GO:0008201^molecular_function^heparin binding,NA,KEGG:hsa:339366,"ENOG410XPKZ^ADAM metallopeptidase with thrombospondin type 1, motif",PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^2-70^E:5.7e-17,PF01759.21^NTR^UNC-6/NTR/C345C module^144-243^E:1.1e-15,NA,NA,NA,,
yes,AD,ADAMTS,DN36536_c0_g1_i10,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^54-170^E:2.5e-24,PF00090.19^TSP_1^Thrombospondin type 1 domain^520-577^E:0.0018,PF00090.19^TSP_1^Thrombospondin type 1 domain^583-629^E:0.0023,PF00090.19^TSP_1^Thrombospondin type 1 domain^636-686^E:0.024,PF00090.19^TSP_1^Thrombospondin type 1 domain^694-746^E:0.0026,,
no,AD,ADAMTS,DN36536_c0_g1_i11,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,.,NA,NA,NA,NA,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN36536_c0_g1_i6,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^44-98^E:1e-06,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^208-324^E:3.2e-24,PF00090.19^TSP_1^Thrombospondin type 1 domain^674-731^E:0.0016,PF00090.19^TSP_1^Thrombospondin type 1 domain^737-783^E:0.0028,PF00090.19^TSP_1^Thrombospondin type 1 domain^790-840^E:0.03,,
no,AD,ADAMTS,DN36536_c0_g1_i2,DN36536_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN36536_c0_g1_i3,DN36536_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^24-81^E:0.00088,PF00090.19^TSP_1^Thrombospondin type 1 domain^87-133^E:0.00072,PF00090.19^TSP_1^Thrombospondin type 1 domain^140-190^E:0.0076,PF00090.19^TSP_1^Thrombospondin type 1 domain^198-250^E:0.0021,PF00090.19^TSP_1^Thrombospondin type 1 domain^256-303^E:1.7e-06,,
no,AD,ADAMTS,DN36536_c0_g1_i5,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,.,NA,NA,NA,NA,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN36536_c0_g1_i8,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,.,NA,NA,NA,NA,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN36536_c0_g1_i12,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^54-170^E:2.5e-24,PF00090.19^TSP_1^Thrombospondin type 1 domain^520-577^E:0.0018,PF00090.19^TSP_1^Thrombospondin type 1 domain^583-629^E:0.0023,PF00090.19^TSP_1^Thrombospondin type 1 domain^636-686^E:0.024,PF00090.19^TSP_1^Thrombospondin type 1 domain^694-746^E:0.0026,,
no,AD,ADAMTS,DN36536_c0_g1_i1,DN36536_c0_g1,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_MOUSE,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^44-96^E:9.1e-06,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i7,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_MOUSE,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^101-127^E:0.00095,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i8,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,.,NA,NA,NA,NA,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i2,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^101-155^E:5e-05,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^265-380^E:4.6e-27,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i4,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^54-169^E:1.7e-27,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i6,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^101-155^E:3.8e-05,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^265-380^E:4.3e-27,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i3,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_MOUSE,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g1_i9,DN5091_c0_g1,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^101-155^E:4.1e-05,PF05986.14^ADAM_spacer1^ADAM-TS Spacer 1^265-380^E:3.5e-27,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g2_i2,DN5091_c0_g2,ATL2_HUMAN,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,.,NA,NA,NA,NA,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g2_i3,DN5091_c0_g2,ATL2_HUMAN,ADAMTS-like protein 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,.,NA,NA,NA,NA,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g2_i1,DN5091_c0_g2,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_MOUSE,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,KEGG:mmu:77794,ENOG410Y9HP^metalloendopeptidase activity,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN5091_c0_g2_i5,DN5091_c0_g2,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^113-137^E:0.00096,PF00090.19^TSP_1^Thrombospondin type 1 domain^176-222^E:0.15,PF00090.19^TSP_1^Thrombospondin type 1 domain^229-279^E:0.00018,PF00090.19^TSP_1^Thrombospondin type 1 domain^286-306^E:0.0028,PF00090.19^TSP_1^Thrombospondin type 1 domain^344-392^E:5.6e-06,,
no,AD,ADAMTS,DN5091_c0_g2_i8,DN5091_c0_g2,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^190-214^E:0.00074,PF00090.19^TSP_1^Thrombospondin type 1 domain^253-299^E:0.18,PF00090.19^TSP_1^Thrombospondin type 1 domain^306-356^E:0.00022,PF00090.19^TSP_1^Thrombospondin type 1 domain^363-383^E:0.0035,PF00090.19^TSP_1^Thrombospondin type 1 domain^421-469^E:7e-06,,
no,AD,ADAMTS,DN5091_c0_g2_i7,DN5091_c0_g2,ATL2_MOUSE,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^64-88^E:0.00083,PF00090.19^TSP_1^Thrombospondin type 1 domain^127-173^E:0.12,PF00090.19^TSP_1^Thrombospondin type 1 domain^180-230^E:0.00015,PF00090.19^TSP_1^Thrombospondin type 1 domain^237-257^E:0.0024,PF00090.19^TSP_1^Thrombospondin type 1 domain^295-343^E:4.7e-06,,
no,AD,ADAMTS,DN5091_c0_g2_i6,DN5091_c0_g2,ATL2_HUMAN,ADAMTS-like protein 2,ATL2_HUMAN,ADAMTS-like protein 2,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,GO:0031012^cellular_component^extracellular matrix,GO:0050436^molecular_function^microfibril binding,GO:0008233^molecular_function^peptidase activity,GO:0030198^biological_process^extracellular matrix organization,GO:0060481^biological_process^lobar bronchus epithelium development,KEGG:hsa:9719,ENOG410Y9HP^metalloendopeptidase activity,PF00090.19^TSP_1^Thrombospondin type 1 domain^64-88^E:0.00083,PF00090.19^TSP_1^Thrombospondin type 1 domain^127-173^E:0.12,PF00090.19^TSP_1^Thrombospondin type 1 domain^180-230^E:0.00015,PF00090.19^TSP_1^Thrombospondin type 1 domain^237-257^E:0.0024,PF00090.19^TSP_1^Thrombospondin type 1 domain^295-343^E:4.7e-06,,
no,AD,ADAMTS,DN92842_c0_g1_i6,DN92842_c0_g1,ATL1_HUMAN,ADAMTS-like protein 1,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:92949,ENOG410YY5R^ADAMTS-like,.,NA,NA,NA,NA,,
no,AD,ADAMTS,DN92842_c0_g1_i9,DN92842_c0_g1,ATL1_HUMAN,ADAMTS-like protein 1,ATL1_HUMAN,ADAMTS-like protein 1,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:92949,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^36-79^E:0.00018,PF00090.19^TSP_1^Thrombospondin type 1 domain^380-404^E:7.2e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^441-478^E:0.00014,PF00090.19^TSP_1^Thrombospondin type 1 domain^528-552^E:7.5e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^671-699^E:7.3e-05,,
no,AD,ADAMTS,DN92842_c0_g1_i11,DN92842_c0_g1,ATL1_HUMAN,ADAMTS-like protein 1,ATL1_HUMAN,ADAMTS-like protein 1,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:92949,ENOG410YY5R^ADAMTS-like,PF00090.19^TSP_1^Thrombospondin type 1 domain^77-120^E:0.00018,PF00090.19^TSP_1^Thrombospondin type 1 domain^421-445^E:7.3e-05,PF00090.19^TSP_1^Thrombospondin type 1 domain^482-519^E:0.00014,PF00090.19^TSP_1^Thrombospondin type 1 domain^569-593^E:7.7e-06,PF00090.19^TSP_1^Thrombospondin type 1 domain^712-740^E:7.5e-05,,
no,AD,ADAMTS,DN92842_c0_g1_i7,DN92842_c0_g1,ATL1_HUMAN,ADAMTS-like protein 1,ATL1_HUMAN,ADAMTS-like protein 1,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0008233^molecular_function^peptidase activity,NA,NA,KEGG:hsa:92949,ENOG410YY5R^ADAMTS-like,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN20654_c0_g1_i7,DN20654_c0_g1,AP1B1_MOUSE,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:mmu:11764`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN20654_c0_g1_i10,DN20654_c0_g1,AP1B1_RAT,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030118^cellular_component^clathrin coat,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0030276^molecular_function^clathrin binding,.,NA,NA,NA,NA,.,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN20654_c0_g1_i4,DN20654_c0_g1,AP1B1_RAT,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030118^cellular_component^clathrin coat,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0030276^molecular_function^clathrin binding,.,NA,NA,NA,NA,.,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2937_c0_g1_i7,DN2937_c0_g1,JUN_CHICK,Transcription factor AP-1,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:424673`KO:K04448,ENOG410XRWH^proto-oncogene,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2937_c0_g1_i13,DN2937_c0_g1,.,NA,JUN_SERCA,Transcription factor AP-1,.,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0007265^biological_process^Ras protein signal transduction,NA,.,.,PF03957.13^Jun^Jun-like transcription factor^20-114^E:8.1e-24,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i5,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-98^E:1.3e-14,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i9,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-181^E:1.3e-59,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i2,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-181^E:9.6e-60,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i3,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-181^E:9.1e-60,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i8,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-181^E:1.3e-59,NA,NA,NA,NA,,
yes,AD,AP-1,DN289_c0_g1_i7,DN289_c0_g1,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,AP1S1_MOUSE,AP-1 complex subunit sigma-1A,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11769`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-181^E:1.3e-59,NA,NA,NA,NA,,
yes,AD,AP-1,DN47991_c0_g1_i2,DN47991_c0_g1,AP1B1_MOUSE,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:mmu:11764`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN20926_c0_g1_i1,DN20926_c0_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN70719_c0_g1_i1,DN70719_c0_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN48326_c0_g1_i1,DN48326_c0_g1,AP1B1_MOUSE,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:mmu:11764`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN8315_c0_g1_i3,DN8315_c0_g1,.,NA,JUN_COTJA,Transcription factor AP-1,.,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0007265^biological_process^Ras protein signal transduction,NA,.,.,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^173-236^E:2.3e-07,PF00170.21^bZIP_1^bZIP transcription factor^179-238^E:7.5e-13,PF07716.15^bZIP_2^Basic region leucine zipper^183-230^E:9.4e-06,NA,NA,,
yes,AD,AP-1,DN8315_c0_g1_i1,DN8315_c0_g1,.,NA,JUN_COTJA,Transcription factor AP-1,.,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0007265^biological_process^Ras protein signal transduction,NA,.,.,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^317-380^E:4.9e-07,PF00170.21^bZIP_1^bZIP transcription factor^323-382^E:1.5e-12,PF07716.15^bZIP_2^Basic region leucine zipper^327-374^E:1.9e-05,NA,NA,,
yes,AD,AP-1,DN88231_c0_g1_i1,DN88231_c0_g1,AP1S2_MOUSE,AP-1 complex subunit sigma-2,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:108012`KO:K12394,.,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i8,DN6567_c0_g1,AP1M1_HUMAN,AP-1 complex subunit mu-1,AP1M1_HUMAN,AP-1 complex subunit mu-1,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:8907`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^9-202^E:1.4e-65,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i3,DN6567_c0_g1,AP1M1_RAT,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:rno:306332`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i11,DN6567_c0_g1,AP1M1_HUMAN,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,.,NA,NA,NA,NA,KEGG:hsa:8907`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i5,DN6567_c0_g1,AP1M1_RAT,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:rno:306332`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i9,DN6567_c0_g1,AP1M1_HUMAN,AP-1 complex subunit mu-1,AP1M1_HUMAN,AP-1 complex subunit mu-1,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:8907`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^67-303^E:5e-82,NA,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g1_i10,DN6567_c0_g1,AP1M1_HUMAN,AP-1 complex subunit mu-1,AP1M1_HUMAN,AP-1 complex subunit mu-1,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:8907`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^118-246^E:5.4e-05,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^270-385^E:1.5e-45,NA,NA,NA,,
yes,AD,AP-1,DN6567_c0_g2_i1,DN6567_c0_g2,AP1M1_RAT,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:rno:306332`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2819_c0_g1_i3,DN2819_c0_g1,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,.,NA,NA,NA,NA,KEGG:hsa:55435,ENOG4111HXC^Adaptor-related protein complex 1 associated regulatory protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2819_c0_g1_i10,DN2819_c0_g1,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,.,NA,NA,NA,NA,KEGG:hsa:55435,ENOG4111HXC^Adaptor-related protein complex 1 associated regulatory protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2819_c0_g1_i4,DN2819_c0_g1,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,.,NA,NA,NA,NA,KEGG:hsa:55435,ENOG4111HXC^Adaptor-related protein complex 1 associated regulatory protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN2819_c0_g1_i5,DN2819_c0_g1,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,.,NA,NA,NA,NA,KEGG:hsa:55435,ENOG4111HXC^Adaptor-related protein complex 1 associated regulatory protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN24410_c0_g1_i8,DN24410_c0_g1,AP1B1_HUMAN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:162`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN24410_c0_g1_i7,DN24410_c0_g1,AP1B1_HUMAN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:162`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN24410_c0_g1_i2,DN24410_c0_g1,AP1B1_HUMAN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:162`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN47103_c0_g1_i2,DN47103_c0_g1,AP1M1_RAT,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:rno:306332`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN47103_c0_g1_i1,DN47103_c0_g1,AP1M1_RAT,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:rno:306332`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4138_c0_g1_i1,DN4138_c0_g1,AP1B1_BOVIN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0030276^molecular_function^clathrin binding,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:bta:282183`KO:K11825,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4138_c0_g2_i1,DN4138_c0_g2,AP1B1_HUMAN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:162`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN1403_c0_g2_i5,DN1403_c0_g2,AP1S2_MOUSE,AP-1 complex subunit sigma-2,AP1S2_MOUSE,AP-1 complex subunit sigma-2,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,KEGG:mmu:108012`KO:K12394,.,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^16-155^E:1.6e-60,NA,NA,NA,NA,,
yes,AD,AP-1,DN1403_c0_g2_i10,DN1403_c0_g2,AP1S2_HUMAN,AP-1 complex subunit sigma-2,AP1S2_HUMAN,AP-1 complex subunit sigma-2,GO:0030119^cellular_component^AP-type membrane coat adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0030119^cellular_component^AP-type membrane coat adaptor complex,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,KEGG:hsa:8905`KO:K12394,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^16-155^E:1.6e-60,NA,NA,NA,NA,,
yes,AD,AP-1,DN1403_c0_g2_i9,DN1403_c0_g2,AP1S2_MOUSE,AP-1 complex subunit sigma-2,AP1S2_MOUSE,AP-1 complex subunit sigma-2,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,KEGG:mmu:108012`KO:K12394,.,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^16-155^E:1.6e-60,NA,NA,NA,NA,,
yes,AD,AP-1,DN36421_c0_g1_i2,DN36421_c0_g1,AP1M1_MOUSE,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:mmu:11767`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN36421_c0_g1_i1,DN36421_c0_g1,AP1M1_MOUSE,AP-1 complex subunit mu-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0035646^biological_process^endosome to melanosome transport,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:mmu:11767`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN35773_c0_g1_i1,DN35773_c0_g1,AP1G1_PONAB,AP-1 complex subunit gamma-1,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173736`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN26645_c0_g1_i4,DN26645_c0_g1,AP1B1_BOVIN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0030276^molecular_function^clathrin binding,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:bta:282183`KO:K11825,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN25831_c0_g1_i1,DN25831_c0_g1,JUN_SERCA,Transcription factor AP-1,JUN_SERCA,Transcription factor AP-1,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0007265^biological_process^Ras protein signal transduction,NA,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0007265^biological_process^Ras protein signal transduction,NA,.,.,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^3-67^E:1.9e-08,PF00170.21^bZIP_1^bZIP transcription factor^5-66^E:1.1e-15,PF07716.15^bZIP_2^Basic region leucine zipper^10-63^E:1.7e-06,NA,NA,,
yes,AD,AP-1,DN25831_c8_g1_i1,DN25831_c8_g1,JUN_CHICK,Transcription factor AP-1,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:424673`KO:K04448,ENOG410XRWH^proto-oncogene,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN99296_c0_g1_i1,DN99296_c0_g1,AP1S2_MOUSE,AP-1 complex subunit sigma-2,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:108012`KO:K12394,.,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN20835_c0_g1_i2,DN20835_c0_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN14849_c0_g2_i1,DN14849_c0_g2,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,AP1AR_HUMAN,AP-1 complex-associated regulatory protein,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005794^cellular_component^Golgi apparatus,GO:0005770^cellular_component^late endosome,KEGG:hsa:55435,ENOG4111HXC^Adaptor-related protein complex 1 associated regulatory protein,PF15745.5^AP1AR^AP-1 complex-associated regulatory protein^84-107^E:6.6e-10,NA,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i2,DN1899_c1_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF02883.20^Alpha_adaptinC2^Adaptin C-terminal domain^146-212^E:2.6e-14,NA,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i6,DN1899_c1_g1,AP1G1_MOUSE,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF01602.20^Adaptin_N^Adaptin N terminal region^160-551^E:4.7e-120,PF12717.7^Cnd1^non-SMC mitotic condensation complex subunit 1^255-361^E:2.3e-10,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i3,DN1899_c1_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF02883.20^Alpha_adaptinC2^Adaptin C-terminal domain^146-258^E:2.8e-36,NA,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i5,DN1899_c1_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF01602.20^Adaptin_N^Adaptin N terminal region^3-105^E:9.8e-15,PF02883.20^Alpha_adaptinC2^Adaptin C-terminal domain^233-345^E:5.2e-36,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i7,DN1899_c1_g1,AP1G1_MOUSE,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF01602.20^Adaptin_N^Adaptin N terminal region^160-551^E:4.7e-120,PF12717.7^Cnd1^non-SMC mitotic condensation complex subunit 1^255-361^E:2.3e-10,NA,NA,NA,,
yes,AD,AP-1,DN1899_c1_g1_i9,DN1899_c1_g1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,AP1G1_HUMAN,AP-1 complex subunit gamma-1,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0030136^cellular_component^clathrin-coated vesicle,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,KEGG:hsa:164`KO:K12391,ENOG410XPKK^Adaptor-related protein complex,PF02883.20^Alpha_adaptinC2^Adaptin C-terminal domain^146-212^E:2.6e-14,NA,NA,NA,NA,,
no,AD,AP-1,DN4959_c0_g1_i2,DN4959_c0_g1,RAP1A_RAT,Ras-related protein Rap-1A,RAP1A_RAT,Ras-related protein Rap-1A,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:295347`KO:K04353,COG1100^GTP-binding Protein,PF00071.22^Ras^Ras family^2-115^E:1.8e-36,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^2-69^E:3.7e-09",NA,NA,NA,,
no,AD,AP-1,DN4959_c0_g1_i1,DN4959_c0_g1,RAP1A_RAT,Ras-related protein Rap-1A,.,NA,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,.,NA,NA,NA,NA,KEGG:rno:295347`KO:K04353,COG1100^GTP-binding Protein,.,NA,NA,NA,NA,,
no,AD,AP-1,DN4959_c0_g1_i5,DN4959_c0_g1,RAP1A_RAT,Ras-related protein Rap-1A,RAP1A_RAT,Ras-related protein Rap-1A,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:295347`KO:K04353,COG1100^GTP-binding Protein,PF00071.22^Ras^Ras family^2-147^E:2.6e-47,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^3-101^E:6.8e-13",PF00025.21^Arf^ADP-ribosylation factor family^14-104^E:5.4e-05,NA,NA,,
no,AD,AP-1,DN4959_c0_g1_i6,DN4959_c0_g1,RAP1A_RAT,Ras-related protein Rap-1A,RAP1A_RAT,Ras-related protein Rap-1A,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:295347`KO:K04353,COG1100^GTP-binding Protein,PF00071.22^Ras^Ras family^2-115^E:1.8e-36,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^2-69^E:3.7e-09",NA,NA,NA,,
no,AD,AP-1,DN4959_c1_g1_i1,DN4959_c1_g1,RAP1B_PONAB,Ras-related protein Rap-1b,RAP1B_PONAB,Ras-related protein Rap-1b,GO:0005911^cellular_component^cell-cell junction,GO:0005829^cellular_component^cytosol,GO:0005811^cellular_component^lipid droplet,GO:0005886^cellular_component^plasma membrane,GO:0019003^molecular_function^GDP binding,GO:0005911^cellular_component^cell-cell junction,GO:0005829^cellular_component^cytosol,GO:0005811^cellular_component^lipid droplet,GO:0005886^cellular_component^plasma membrane,GO:0019003^molecular_function^GDP binding,KEGG:pon:100171907`KO:K07836,COG1100^GTP-binding Protein,PF00025.21^Arf^ADP-ribosylation factor family^2-123^E:1e-08,PF00071.22^Ras^Ras family^5-160^E:1.3e-55,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^5-120^E:7.7e-21",NA,NA,,
no,AD,AP-1,DN4959_c1_g2_i1,DN4959_c1_g2,RAP1B_RAT,Ras-related protein Rap-1b,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005829^cellular_component^cytosol,GO:0005811^cellular_component^lipid droplet,GO:0005886^cellular_component^plasma membrane,GO:0019003^molecular_function^GDP binding,.,NA,NA,NA,NA,KEGG:rno:171337`KO:K07836,COG1100^GTP-binding Protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i7,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i4,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i17,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i9,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i13,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN4960_c0_g1_i8,DN4960_c0_g1,AP1S3_MOUSE,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030117^cellular_component^membrane coat,.,NA,NA,NA,NA,KEGG:mmu:252903`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN37202_c0_g1_i3,DN37202_c0_g1,AP1B1_MOUSE,AP-1 complex subunit beta-1,AP1B1_MOUSE,AP-1 complex subunit beta-1,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:11764`KO:K12392,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN1394_c1_g1_i3,DN1394_c1_g1,JUN_CHICK,Transcription factor AP-1,JUN_CHICK,Transcription factor AP-1,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",KEGG:gga:424673`KO:K04448,ENOG410XRWH^proto-oncogene,PF03957.13^Jun^Jun-like transcription factor^5-225^E:5.2e-94,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^232-296^E:1.5e-08,PF00170.21^bZIP_1^bZIP transcription factor^234-297^E:1.8e-17,PF07716.15^bZIP_2^Basic region leucine zipper^239-294^E:6.3e-09,NA,,
yes,AD,AP-1,DN1394_c1_g1_i1,DN1394_c1_g1,JUN_CHICK,Transcription factor AP-1,JUN_CHICK,Transcription factor AP-1,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",KEGG:gga:424673`KO:K04448,ENOG410XRWH^proto-oncogene,PF03957.13^Jun^Jun-like transcription factor^5-225^E:5.2e-94,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^232-296^E:1.5e-08,PF00170.21^bZIP_1^bZIP transcription factor^234-297^E:1.8e-17,PF07716.15^bZIP_2^Basic region leucine zipper^239-294^E:6.3e-09,NA,,
yes,AD,AP-1,DN1394_c1_g1_i2,DN1394_c1_g1,JUN_CHICK,Transcription factor AP-1,JUN_CHICK,Transcription factor AP-1,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",KEGG:gga:424673`KO:K04448,ENOG410XRWH^proto-oncogene,PF03957.13^Jun^Jun-like transcription factor^5-225^E:5.2e-94,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^232-296^E:1.5e-08,PF00170.21^bZIP_1^bZIP transcription factor^234-297^E:1.8e-17,PF07716.15^bZIP_2^Basic region leucine zipper^239-294^E:6.3e-09,NA,,
yes,AD,AP-1,DN20060_c0_g1_i7,DN20060_c0_g1,RAP1A_RAT,Ras-related protein Rap-1A,.,NA,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0098978^cellular_component^glutamatergic synapse,.,NA,NA,NA,NA,KEGG:rno:295347`KO:K04353,COG1100^GTP-binding Protein,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i4,DN5310_c0_g1,AP1M2_BOVIN,AP-1 complex subunit mu-2,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,.,NA,NA,NA,NA,KEGG:bta:515766`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i6,DN5310_c0_g1,AP1M2_HUMAN,AP-1 complex subunit mu-2,AP1M2_BOVIN,AP-1 complex subunit mu-2,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0000139^cellular_component^Golgi membrane,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,KEGG:bta:515766`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^1-67^E:2.9e-14,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i1,DN5310_c0_g1,AP1M2_BOVIN,AP-1 complex subunit mu-2,AP1M2_MOUSE,AP-1 complex subunit mu-2,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005802^cellular_component^trans-Golgi network,GO:0006886^biological_process^intracellular protein transport,KEGG:mmu:11768`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^24-87^E:1.6e-22,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i5,DN5310_c0_g1,AP1M2_BOVIN,AP-1 complex subunit mu-2,AP1M2_BOVIN,AP-1 complex subunit mu-2,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,KEGG:bta:515766`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^33-158^E:5.9e-36,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i8,DN5310_c0_g1,AP1M2_BOVIN,AP-1 complex subunit mu-2,AP1M2_MOUSE,AP-1 complex subunit mu-2,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005802^cellular_component^trans-Golgi network,GO:0006886^biological_process^intracellular protein transport,KEGG:mmu:11768`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF00928.21^Adap_comp_sub^Adaptor complexes medium subunit family^1-86^E:4.2e-18,NA,NA,NA,NA,,
yes,AD,AP-1,DN5310_c0_g1_i3,DN5310_c0_g1,AP1M2_BOVIN,AP-1 complex subunit mu-2,AP1M2_BOVIN,AP-1 complex subunit mu-2,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,KEGG:bta:515766`KO:K12393,ENOG410XPFS^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^42-166^E:2.2e-08,NA,NA,NA,NA,,
yes,AD,AP-1,DN125019_c0_g1_i1,DN125019_c0_g1,AP1S3_HUMAN,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0000139^cellular_component^Golgi membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:130340`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,AD,AP-1,DN170116_c0_g1_i1,DN170116_c0_g1,AP1B1_BOVIN,AP-1 complex subunit beta-1,.,NA,GO:0030131^cellular_component^clathrin adaptor complex,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0030276^molecular_function^clathrin binding,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:bta:282183`KO:K11825,"COG5096^The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins",.,NA,NA,NA,NA,,
yes,AD,AP-1,DN410697_c0_g1_i1,DN410697_c0_g1,AP1S3_HUMAN,AP-1 complex subunit sigma-3,.,NA,GO:0005905^cellular_component^clathrin-coated pit,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0000139^cellular_component^Golgi membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:130340`KO:K12395,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,AD,B2M,DN3176_c1_g1_i5,DN3176_c1_g1,TFB2M_RAT,"Dimethyladenosine transferase 2, mitochondrial",TFB2M_RAT,"Dimethyladenosine transferase 2, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,KEGG:rno:289307`KO:K17653,COG0030^Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity),.,NA,NA,NA,NA,,
no,AD,B2M,DN3176_c1_g1_i4,DN3176_c1_g1,TFB2M_BOVIN,"Dimethyladenosine transferase 2, mitochondrial",TFB2M_RAT,"Dimethyladenosine transferase 2, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,KEGG:rno:289307`KO:K17653,COG0030^Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity),PF00398.20^RrnaAD^Ribosomal RNA adenine dimethylase^37-308^E:2.3e-12,NA,NA,NA,NA,,
no,AD,B2M,DN3176_c1_g1_i2,DN3176_c1_g1,TFB2M_BOVIN,"Dimethyladenosine transferase 2, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:bta:516874`KO:K17653,COG0030^Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity),.,NA,NA,NA,NA,,
no,AD,B2M,DN3176_c1_g1_i7,DN3176_c1_g1,TFB2M_BOVIN,"Dimethyladenosine transferase 2, mitochondrial",TFB2M_BOVIN,"Dimethyladenosine transferase 2, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0003723^molecular_function^RNA binding,"GO:0000179^molecular_function^rRNA (adenine-N6,N6-)-dimethyltransferase activity",GO:0003712^molecular_function^transcription coregulator activity,KEGG:bta:516874`KO:K17653,COG0030^Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity),PF00398.20^RrnaAD^Ribosomal RNA adenine dimethylase^94-374^E:3.7e-16,NA,NA,NA,NA,,
yes,AD,B2M,DN2680_c0_g1_i6,DN2680_c0_g1,B2MG_MELGA,Beta-2-microglobulin,B2MG_MELGA,Beta-2-microglobulin,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^30-109^E:1.3e-20,NA,NA,NA,NA,,
yes,AD,B2M,DN2680_c0_g1_i5,DN2680_c0_g1,B2MG_MELGA,Beta-2-microglobulin,B2MG_MELGA,Beta-2-microglobulin,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^30-109^E:2.3e-20,NA,NA,NA,NA,,
yes,AD,B2M,DN2680_c0_g1_i3,DN2680_c0_g1,B2MG_MELGA,Beta-2-microglobulin,B2MG_MELGA,Beta-2-microglobulin,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^30-109^E:2.3e-20,NA,NA,NA,NA,,
yes,AD,B2M,DN2680_c0_g1_i1,DN2680_c0_g1,B2MG_MELGA,Beta-2-microglobulin,B2MG_MELGA,Beta-2-microglobulin,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,GO:0005576^cellular_component^extracellular region,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0006955^biological_process^immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^30-109^E:1.3e-20,NA,NA,NA,NA,,
yes,AD,BDNF,DN50478_c0_g1_i2,DN50478_c0_g1,BDNF_CHICK,Brain-derived neurotrophic factor,BDNF_CHICK,Brain-derived neurotrophic factor,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0030425^cellular_component^dendrite,GO:0005615^cellular_component^extracellular space,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0030425^cellular_component^dendrite,GO:0005615^cellular_component^extracellular space,KEGG:gga:396186`KO:K04355,"ENOG410XRPH^During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS",PF00243.18^NGF^Nerve growth factor family^133-243^E:2.3e-46,NA,NA,NA,NA,,
yes,AD,BDNF,DN50478_c0_g1_i1,DN50478_c0_g1,BDNF_CHICK,Brain-derived neurotrophic factor,BDNF_CHICK,Brain-derived neurotrophic factor,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0030425^cellular_component^dendrite,GO:0005615^cellular_component^extracellular space,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0030425^cellular_component^dendrite,GO:0005615^cellular_component^extracellular space,KEGG:gga:396186`KO:K04355,"ENOG410XRPH^During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS",PF00243.18^NGF^Nerve growth factor family^133-243^E:2.3e-46,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i9,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i11,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i5,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i7,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^202-271^E:0.037,PF13855.6^LRR_8^Leucine rich repeat^227-284^E:4.3e-09,PF00560.33^LRR_1^Leucine Rich Repeat^251-273^E:1.5,PF16920.5^TPKR_C2^Tyrosine-protein kinase receptor C2 Ig-like domain^286-330^E:1.8e-13,PF13927.6^Ig_3^Immunoglobulin domain^333-405^E:1.2e-10,,
yes,AD,BDNF,DN1722_c0_g1_i8,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i1,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i3,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i10,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^35-303^E:1.8e-97,PF00069.25^Pkinase^Protein kinase domain^36-300^E:2e-49,NA,NA,NA,,
yes,AD,BDNF,DN1722_c0_g1_i4,DN1722_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^2-94^E:1.9e-34,PF00069.25^Pkinase^Protein kinase domain^5-91^E:2.1e-13,NA,NA,NA,,
yes,AD,BDNF,DN447165_c0_g1_i1,DN447165_c0_g1,NTRK2_CHICK,BDNF/NT-3 growth factors receptor,.,NA,GO:0030424^cellular_component^axon,GO:0043679^cellular_component^axon terminus,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,.,NA,NA,NA,NA,KEGG:gga:396157`KO:K04360,"ENOG410YGKQ^neurotrophic tyrosine kinase, receptor, type",.,NA,NA,NA,NA,,
yes,AD,BMP,DN6055_c0_g1_i6,DN6055_c0_g1,BMP2_CHICK,Bone morphogenetic protein 2,.,NA,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,NA,NA,NA,NA,.,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,BMP,DN6055_c0_g1_i10,DN6055_c0_g1,BMP2_CHICK,Bone morphogenetic protein 2,BMP2_CHICK,Bone morphogenetic protein 2,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^50-269^E:1.8e-52,PF00019.20^TGF_beta^Transforming growth factor beta like domain^297-397^E:3.8e-34,NA,NA,NA,,
yes,AD,BMP,DN96276_c0_g1_i1,DN96276_c0_g1,BMP3_XENLA,Bone morphogenetic protein 3,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0016015^molecular_function^morphogen activity,GO:0009653^biological_process^anatomical structure morphogenesis,.,NA,NA,NA,NA,KEGG:xla:399354`KO:K05496,.,.,NA,NA,NA,NA,,
yes,AD,BMP,DN68381_c0_g1_i3,DN68381_c0_g1,BMP4_CHICK,Bone morphogenetic protein 4,BMP4_CHICK,Bone morphogenetic protein 4,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^29-160^E:2e-18,PF00019.20^TGF_beta^Transforming growth factor beta like domain^208-310^E:8e-32,NA,NA,NA,,
yes,AD,BMP,DN68381_c0_g1_i2,DN68381_c0_g1,BMP2_HUMAN,Bone morphogenetic protein 2,BMP2_HUMAN,Bone morphogenetic protein 2,GO:0070724^cellular_component^BMP receptor complex,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0070724^cellular_component^BMP receptor complex,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:hsa:650`KO:K21283,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^2-173^E:1.7e-21,PF00019.20^TGF_beta^Transforming growth factor beta like domain^221-323^E:8.7e-32,NA,NA,NA,,
yes,AD,BMP,DN15123_c0_g1_i4,DN15123_c0_g1,BMP8A_MOUSE,Bone morphogenetic protein 8A,BMP8A_MOUSE,Bone morphogenetic protein 8A,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,KEGG:mmu:12163`KO:K16622,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^3-142^E:4.3e-46,PF00019.20^TGF_beta^Transforming growth factor beta like domain^191-292^E:1.7e-37,NA,NA,NA,,
yes,AD,BMP,DN3917_c1_g2_i1,DN3917_c1_g2,BMP1_MOUSE,Bone morphogenetic protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:12153`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN3917_c1_g2_i3,DN3917_c1_g2,BMP1_MOUSE,Bone morphogenetic protein 1,BMP1_MOUSE,Bone morphogenetic protein 1,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12153`KO:K05502,ENOG410ZPX7^Meprin A,PF00431.20^CUB^CUB domain^1-38^E:4.5e-06,PF00431.20^CUB^CUB domain^42-151^E:2e-42,PF07645.15^EGF_CA^Calcium-binding EGF domain^155-194^E:9.4e-07,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^162-194^E:9.1e-11,PF12661.7^hEGF^Human growth factor-like EGF^169-185^E:0.007,,
yes,AD,BMP,DN3917_c1_g2_i4,DN3917_c1_g2,BMP1_HUMAN,Bone morphogenetic protein 1,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:hsa:649`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN3917_c1_g2_i5,DN3917_c1_g2,BMP1_MOUSE,Bone morphogenetic protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:12153`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN3917_c1_g2_i2,DN3917_c1_g2,BMP1_HUMAN,Bone morphogenetic protein 1,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:hsa:649`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8026_c0_g1_i2,DN8026_c0_g1,BMP5_HUMAN,Bone morphogenetic protein 5,BMP5_HUMAN,Bone morphogenetic protein 5,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:653`KO:K04663,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^1-224^E:3.6e-71,PF00019.20^TGF_beta^Transforming growth factor beta like domain^272-374^E:4e-37,NA,NA,NA,,
yes,AD,BMP,DN8026_c0_g1_i1,DN8026_c0_g1,BMP5_HUMAN,Bone morphogenetic protein 5,BMP5_HUMAN,Bone morphogenetic protein 5,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:653`KO:K04663,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^29-302^E:2.4e-93,PF00019.20^TGF_beta^Transforming growth factor beta like domain^350-452^E:5.6e-37,NA,NA,NA,,
yes,AD,BMP,DN2504_c0_g1_i6,DN2504_c0_g1,BAMBI_HUMAN,BMP and activin membrane-bound inhibitor homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005109^molecular_function^frizzled binding,GO:0005114^molecular_function^type II transforming growth factor beta receptor binding,.,NA,NA,NA,NA,KEGG:hsa:25805`KO:K10162,ENOG4110R2C^BMP and activin membrane-bound inhibitor homolog (Xenopus laevis),.,NA,NA,NA,NA,,
yes,AD,BMP,DN2504_c0_g1_i2,DN2504_c0_g1,BAMBI_HUMAN,BMP and activin membrane-bound inhibitor homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005109^molecular_function^frizzled binding,GO:0005114^molecular_function^type II transforming growth factor beta receptor binding,.,NA,NA,NA,NA,KEGG:hsa:25805`KO:K10162,ENOG4110R2C^BMP and activin membrane-bound inhibitor homolog (Xenopus laevis),.,NA,NA,NA,NA,,
yes,AD,BMP,DN2504_c0_g1_i8,DN2504_c0_g1,BAMBI_HUMAN,BMP and activin membrane-bound inhibitor homolog,BAMBI_HUMAN,BMP and activin membrane-bound inhibitor homolog,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005109^molecular_function^frizzled binding,GO:0005114^molecular_function^type II transforming growth factor beta receptor binding,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005109^molecular_function^frizzled binding,GO:0005114^molecular_function^type II transforming growth factor beta receptor binding,KEGG:hsa:25805`KO:K10162,ENOG4110R2C^BMP and activin membrane-bound inhibitor homolog (Xenopus laevis),PF06211.12^BAMBI^BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain^4-111^E:1.1e-61,NA,NA,NA,NA,,
no,AD,BMP,DN6555_c0_g1_i6,DN6555_c0_g1,OSGP2_HUMAN,"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03179}",CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0000408^cellular_component^EKC/KEOPS complex,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0004222^molecular_function^metalloendopeptidase activity,GO:0061711^molecular_function^N(6)-L-threonylcarbamoyladenine synthase activity,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00219.18^IGFBP^Insulin-like growth factor binding protein^48-101^E:6e-09,NA,NA,NA,NA,,
no,AD,BMP,DN6555_c0_g1_i5,DN6555_c0_g1,OSGP2_HUMAN,"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03179}",CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0000408^cellular_component^EKC/KEOPS complex,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0004222^molecular_function^metalloendopeptidase activity,GO:0061711^molecular_function^N(6)-L-threonylcarbamoyladenine synthase activity,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00219.18^IGFBP^Insulin-like growth factor binding protein^48-101^E:6e-09,NA,NA,NA,NA,,
yes,AD,BMP,DN34204_c0_g1_i2,DN34204_c0_g1,BMP1_MOUSE,Bone morphogenetic protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:12153`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN34204_c0_g2_i1,DN34204_c0_g2,BMP1_XENLA,Bone morphogenetic protein 1,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0005509^molecular_function^calcium ion binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,BMP,DN15314_c0_g1_i12,DN15314_c0_g1,BMP1_HUMAN,Bone morphogenetic protein 1,TLL1_DANRE,Dorsal-ventral patterning tolloid-like protein 1,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0004222^molecular_function^metalloendopeptidase activity,GO:0008237^molecular_function^metallopeptidase activity,GO:0008233^molecular_function^peptidase activity,KEGG:dre:474335`KO:K09608,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN43934_c0_g1_i2,DN43934_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN43934_c0_g1_i4,DN43934_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN58383_c0_g1_i2,DN58383_c0_g1,BMP1_MOUSE,Bone morphogenetic protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005794^cellular_component^Golgi apparatus,GO:0031982^cellular_component^vesicle,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:12153`KO:K05502,ENOG410ZPX7^Meprin A,.,NA,NA,NA,NA,,
yes,AD,BMP,DN50312_c0_g1_i1,DN50312_c0_g1,BMP15_BOVIN,Bone morphogenetic protein 15,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,NA,NA,NA,NA,KEGG:bta:353351`KO:K05498,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,BMP,DN50312_c0_g1_i2,DN50312_c0_g1,BMP15_BOVIN,Bone morphogenetic protein 15,BMP15_BOVIN,Bone morphogenetic protein 15,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,KEGG:bta:353351`KO:K05498,ENOG410XT8Z^bone morphogenetic protein,PF00019.20^TGF_beta^Transforming growth factor beta like domain^255-356^E:2.6e-28,NA,NA,NA,NA,,
yes,AD,BMP,DN4899_c1_g1_i1,DN4899_c1_g1,BMP4_CHICK,Bone morphogenetic protein 4,BMP4_CHICK,Bone morphogenetic protein 4,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^27-169^E:2.1e-34,PF00019.20^TGF_beta^Transforming growth factor beta like domain^197-297^E:9.5e-34,NA,NA,NA,,
yes,AD,BMP,DN4899_c1_g1_i3,DN4899_c1_g1,BMP4_CHICK,Bone morphogenetic protein 4,BMP4_CHICK,Bone morphogenetic protein 4,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^97-324^E:1.6e-54,PF00019.20^TGF_beta^Transforming growth factor beta like domain^352-452^E:2.1e-33,NA,NA,NA,,
yes,AD,BMP,DN4899_c1_g1_i2,DN4899_c1_g1,BMP4_CHICK,Bone morphogenetic protein 4,BMP4_CHICK,Bone morphogenetic protein 4,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^113-340^E:1.7e-54,PF00019.20^TGF_beta^Transforming growth factor beta like domain^368-468^E:2.2e-33,NA,NA,NA,,
yes,AD,BMP,DN3055_c0_g1_i4,DN3055_c0_g1,BMP2K_MOUSE,BMP-2-inducible protein kinase,BMP2K_MOUSE,BMP-2-inducible protein kinase,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,KEGG:mmu:140780`KO:K08854,ENOG410Y515^associated kinase,.,NA,NA,NA,NA,,
yes,AD,BMP,DN3055_c0_g1_i6,DN3055_c0_g1,BMP2K_HUMAN,BMP-2-inducible protein kinase,BMP2K_HUMAN,BMP-2-inducible protein kinase,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,KEGG:hsa:55589`KO:K08854,ENOG410Y515^associated kinase,PF15282.6^BMP2K_C^BMP-2-inducible protein kinase C-terminus^246-513^E:2.1e-119,NA,NA,NA,NA,,
yes,AD,BMP,DN3055_c0_g1_i1,DN3055_c0_g1,BMP2K_MOUSE,BMP-2-inducible protein kinase,BMP2K_HUMAN,BMP-2-inducible protein kinase,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,KEGG:hsa:55589`KO:K08854,ENOG410Y515^associated kinase,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^57-314^E:3.1e-26,PF00069.25^Pkinase^Protein kinase domain^58-316^E:9.5e-43,PF14531.6^Kinase-like^Kinase-like^143-309^E:4.5e-08,NA,NA,,
yes,AD,BMP,DN3055_c0_g1_i7,DN3055_c0_g1,BMP2K_HUMAN,BMP-2-inducible protein kinase,BMP2K_MOUSE,BMP-2-inducible protein kinase,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,KEGG:mmu:140780`KO:K08854,ENOG410Y515^associated kinase,.,NA,NA,NA,NA,,
yes,AD,BMP,DN3055_c0_g1_i2,DN3055_c0_g1,BMP2K_MOUSE,BMP-2-inducible protein kinase,BMP2K_MOUSE,BMP-2-inducible protein kinase,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,KEGG:mmu:140780`KO:K08854,ENOG410Y515^associated kinase,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^57-312^E:4.3e-25,PF00069.25^Pkinase^Protein kinase domain^58-316^E:1.4e-41,PF14531.6^Kinase-like^Kinase-like^145-309^E:4.2e-07,PF15282.6^BMP2K_C^BMP-2-inducible protein kinase C-terminus^867-1134^E:1.1e-118,NA,,
yes,AD,BMP,DN3055_c0_g1_i5,DN3055_c0_g1,BMP2K_HUMAN,BMP-2-inducible protein kinase,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,.,NA,NA,NA,NA,KEGG:hsa:55589`KO:K08854,ENOG410Y515^associated kinase,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i16,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i2,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,.,NA,NA,NA,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i19,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00219.18^IGFBP^Insulin-like growth factor binding protein^163-216^E:1.8e-07,PF00093.18^VWC^von Willebrand factor type C domain^462-516^E:4.8e-07,PF00093.18^VWC^von Willebrand factor type C domain^529-582^E:4.1e-07,PF02822.14^Antistasin^Antistasin family^599-624^E:2.6e-05,PF02822.14^Antistasin^Antistasin family^635-658^E:1.9e-06,,
yes,AD,BMP,DN8881_c0_g1_i17,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^35-89^E:2.6e-07,PF00093.18^VWC^von Willebrand factor type C domain^102-155^E:2.2e-07,PF02822.14^Antistasin^Antistasin family^172-197^E:1.2e-05,PF02822.14^Antistasin^Antistasin family^208-231^E:1.1e-06,PF02822.14^Antistasin^Antistasin family^238-263^E:6.2e-07,,
yes,AD,BMP,DN8881_c0_g1_i25,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,.,NA,NA,NA,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i21,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF02822.14^Antistasin^Antistasin family^3-23^E:7.9e-05,PF00093.18^VWC^von Willebrand factor type C domain^42-93^E:8.2e-08,PF00093.18^VWC^von Willebrand factor type C domain^115-165^E:3.5e-10,PF00093.18^VWC^von Willebrand factor type C domain^188-239^E:5.5e-09,PF00093.18^VWC^von Willebrand factor type C domain^250-304^E:1.5e-11,,
yes,AD,BMP,DN8881_c0_g1_i9,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^35-89^E:2.2e-07,PF00093.18^VWC^von Willebrand factor type C domain^102-155^E:1.9e-07,PF02822.14^Antistasin^Antistasin family^172-197^E:9e-06,PF02822.14^Antistasin^Antistasin family^204-231^E:9.4e-07,PF02822.14^Antistasin^Antistasin family^238-263^E:5.4e-07,,
yes,AD,BMP,DN8881_c0_g1_i12,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i24,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^35-89^E:4e-08,PF00093.18^VWC^von Willebrand factor type C domain^102-155^E:3.4e-08,PF02822.14^Antistasin^Antistasin family^172-197^E:2.1e-06,NA,NA,,
yes,AD,BMP,DN8881_c0_g1_i6,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^35-89^E:2.7e-07,PF00093.18^VWC^von Willebrand factor type C domain^102-155^E:2.3e-07,PF02822.14^Antistasin^Antistasin family^172-197^E:1.3e-05,PF02822.14^Antistasin^Antistasin family^208-231^E:1.1e-06,PF02822.14^Antistasin^Antistasin family^238-263^E:6.6e-07,,
yes,AD,BMP,DN8881_c0_g1_i20,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00219.18^IGFBP^Insulin-like growth factor binding protein^163-216^E:1.7e-07,PF00093.18^VWC^von Willebrand factor type C domain^462-516^E:4.6e-07,PF00093.18^VWC^von Willebrand factor type C domain^529-582^E:3.9e-07,PF02822.14^Antistasin^Antistasin family^599-624^E:2.5e-05,PF02822.14^Antistasin^Antistasin family^635-658^E:1.8e-06,,
yes,AD,BMP,DN8881_c0_g1_i10,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^35-89^E:2.7e-07,PF00093.18^VWC^von Willebrand factor type C domain^102-155^E:2.3e-07,PF02822.14^Antistasin^Antistasin family^172-197^E:1.3e-05,PF02822.14^Antistasin^Antistasin family^208-231^E:1.1e-06,PF02822.14^Antistasin^Antistasin family^238-263^E:6.6e-07,,
yes,AD,BMP,DN8881_c0_g1_i15,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF02822.14^Antistasin^Antistasin family^3-23^E:7.9e-05,PF00093.18^VWC^von Willebrand factor type C domain^42-93^E:8.2e-08,PF00093.18^VWC^von Willebrand factor type C domain^115-165^E:3.5e-10,PF00093.18^VWC^von Willebrand factor type C domain^188-239^E:5.5e-09,PF00093.18^VWC^von Willebrand factor type C domain^250-304^E:1.5e-11,,
yes,AD,BMP,DN8881_c0_g1_i11,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00093.18^VWC^von Willebrand factor type C domain^26-79^E:1.9e-07,PF02822.14^Antistasin^Antistasin family^96-121^E:9e-06,PF02822.14^Antistasin^Antistasin family^128-155^E:9.4e-07,PF02822.14^Antistasin^Antistasin family^162-187^E:5.4e-07,PF02822.14^Antistasin^Antistasin family^190-215^E:1.7e-05,,
yes,AD,BMP,DN8881_c0_g1_i7,DN8881_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,PF00219.18^IGFBP^Insulin-like growth factor binding protein^163-216^E:4e-08,NA,NA,NA,NA,,
yes,AD,BMP,DN61203_c0_g1_i1,DN61203_c0_g1,BRNP2_RAT,BMP/retinoic acid-inducible neural-specific protein 2,BRNP2_RAT,BMP/retinoic acid-inducible neural-specific protein 2,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,KEGG:rno:286895,"ENOG410XQ74^family with sequence similarity 5, member",.,NA,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g2_i3,DN313_c0_g2,BMP7_MOUSE,Bone morphogenetic protein 7,BMP7_MOUSE,Bone morphogenetic protein 7,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:mmu:12162`KO:K16621,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^49-299^E:1e-92,PF00019.20^TGF_beta^Transforming growth factor beta like domain^347-449^E:9.6e-37,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g2_i2,DN313_c0_g2,BMP7_MOUSE,Bone morphogenetic protein 7,BMP7_MOUSE,Bone morphogenetic protein 7,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:mmu:12162`KO:K16621,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^49-272^E:1.4e-83,NA,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g2_i1,DN313_c0_g2,BMP7_MOUSE,Bone morphogenetic protein 7,BMP7_MOUSE,Bone morphogenetic protein 7,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:mmu:12162`KO:K16621,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^49-299^E:8.8e-93,NA,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g2_i4,DN313_c0_g2,BMP7_MOUSE,Bone morphogenetic protein 7,BMP7_MOUSE,Bone morphogenetic protein 7,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:mmu:12162`KO:K16621,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^49-299^E:5.1e-93,NA,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g5_i2,DN313_c0_g5,BMP6_RAT,Bone morphogenetic protein 6,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:rno:25644`KO:K16620,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g5_i1,DN313_c0_g5,BMP6_RAT,Bone morphogenetic protein 6,BMP6_RAT,Bone morphogenetic protein 6,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:rno:25644`KO:K16620,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^45-288^E:3e-94,PF00019.20^TGF_beta^Transforming growth factor beta like domain^337-438^E:4.5e-38,NA,NA,NA,,
yes,AD,BMP,DN313_c0_g5_i3,DN313_c0_g5,BMP6_MOUSE,Bone morphogenetic protein 6,BMP6_MOUSE,Bone morphogenetic protein 6,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:mmu:12161`KO:K16620,ENOG410XT8Z^bone morphogenetic protein,PF00019.20^TGF_beta^Transforming growth factor beta like domain^48-141^E:2.8e-30,NA,NA,NA,NA,,
yes,AD,BMP,DN739_c2_g1_i2,DN739_c2_g1,BMPER_MOUSE,BMP-binding endothelial regulator protein,BMPER_MOUSE,BMP-binding endothelial regulator protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0002043^biological_process^blood vessel endothelial cell proliferation involved in sprouting angiogenesis,GO:0042118^biological_process^endothelial cell activation,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0002043^biological_process^blood vessel endothelial cell proliferation involved in sprouting angiogenesis,GO:0042118^biological_process^endothelial cell activation,KEGG:mmu:73230,ENOG410XW0S^BMP binding endothelial regulator,PF00093.18^VWC^von Willebrand factor type C domain^162-220^E:7e-10,PF00093.18^VWC^von Willebrand factor type C domain^297-341^E:7e-08,PF00094.25^VWD^von Willebrand factor type D domain^341-449^E:2.2e-17,PF08742.11^C8^C8 domain^498-562^E:1.4e-14,PF01826.17^TIL^Trypsin Inhibitor like cysteine rich domain^567-620^E:3.2e-10,,
yes,AD,BMP,DN739_c2_g1_i1,DN739_c2_g1,BMPER_MOUSE,BMP-binding endothelial regulator protein,BMPER_MOUSE,BMP-binding endothelial regulator protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0002043^biological_process^blood vessel endothelial cell proliferation involved in sprouting angiogenesis,GO:0042118^biological_process^endothelial cell activation,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0002043^biological_process^blood vessel endothelial cell proliferation involved in sprouting angiogenesis,GO:0042118^biological_process^endothelial cell activation,KEGG:mmu:73230,ENOG410XW0S^BMP binding endothelial regulator,PF00093.18^VWC^von Willebrand factor type C domain^162-220^E:7.8e-10,PF00093.18^VWC^von Willebrand factor type C domain^297-353^E:3.7e-09,PF00094.25^VWD^von Willebrand factor type D domain^360-507^E:2.4e-36,PF08742.11^C8^C8 domain^556-620^E:1.6e-14,PF01826.17^TIL^Trypsin Inhibitor like cysteine rich domain^625-678^E:3.6e-10,,
yes,AD,BMP,DN2228_c2_g1_i9,DN2228_c2_g1,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,KEGG:mmu:12168`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,PF01064.23^Activin_recp^Activin types I and II receptor domain^84-162^E:1.3e-11,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^242-534^E:6e-29,PF00069.25^Pkinase^Protein kinase domain^244-535^E:1.6e-32,NA,NA,,
yes,AD,BMP,DN2228_c2_g1_i3,DN2228_c2_g1,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,DEN2D_HUMAN,DENN domain-containing protein 2D,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,NA,NA,KEGG:hsa:79961`KO:K20161,ENOG410XT3N^Rab guanyl-nucleotide exchange factor activity,PF03456.18^uDENN^uDENN domain^130-197^E:5.9e-15,PF02141.21^DENN^DENN (AEX-3) domain^207-389^E:3.9e-57,PF03455.19^dDENN^dDENN domain^463-508^E:7.3e-09,NA,NA,,
yes,AD,BMP,DN2228_c2_g1_i8,DN2228_c2_g1,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,KEGG:mmu:12168`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,PF01064.23^Activin_recp^Activin types I and II receptor domain^49-127^E:1.2e-11,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^207-499^E:5.6e-29,PF00069.25^Pkinase^Protein kinase domain^209-500^E:1.5e-32,NA,NA,,
yes,AD,BMP,DN1355_c2_g1_i1,DN1355_c2_g1,BMP3_MOUSE,Bone morphogenetic protein 3,BMP3_MOUSE,Bone morphogenetic protein 3,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:mmu:110075`KO:K05496,ENOG410XT8Z^bone morphogenetic protein,PF00019.20^TGF_beta^Transforming growth factor beta like domain^442-544^E:2e-30,NA,NA,NA,NA,,
yes,AD,BMP,DN95201_c0_g1_i2,DN95201_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,.,NA,NA,NA,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN126440_c0_g1_i1,DN126440_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN126440_c1_g1_i1,DN126440_c1_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN124401_c1_g1_i1,DN124401_c1_g1,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:mmu:12168`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN198298_c0_g1_i1,DN198298_c0_g1,BRNP2_MOUSE,BMP/retinoic acid-inducible neural-specific protein 2,BRNP2_MOUSE,BMP/retinoic acid-inducible neural-specific protein 2,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,KEGG:mmu:240843,"ENOG410XQ74^family with sequence similarity 5, member",PF01823.19^MACPF^MAC/Perforin domain^13-73^E:1.3e-05,NA,NA,NA,NA,,
yes,AD,BMP,DN108162_c0_g1_i1,DN108162_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN111798_c0_g1_i1,DN111798_c0_g1,BRNP2_RAT,BMP/retinoic acid-inducible neural-specific protein 2,BRNP2_RAT,BMP/retinoic acid-inducible neural-specific protein 2,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0043025^cellular_component^neuronal cell body,GO:0007050^biological_process^cell cycle arrest,KEGG:rno:286895,"ENOG410XQ74^family with sequence similarity 5, member",.,NA,NA,NA,NA,,
yes,AD,BMP,DN207036_c1_g1_i1,DN207036_c1_g1,BRNP3_HUMAN,BMP/retinoic acid-inducible neural-specific protein 3,BRNP3_HUMAN,BMP/retinoic acid-inducible neural-specific protein 3,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0043025^cellular_component^neuronal cell body,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0043025^cellular_component^neuronal cell body,KEGG:hsa:339479,"ENOG410XQ74^family with sequence similarity 5, member",PF01823.19^MACPF^MAC/Perforin domain^53-169^E:6.3e-07,NA,NA,NA,NA,,
yes,AD,BMP,DN272462_c0_g1_i1,DN272462_c0_g1,BMP2K_HUMAN,BMP-2-inducible protein kinase,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004674^molecular_function^protein serine/threonine kinase activity,.,NA,NA,NA,NA,KEGG:hsa:55589`KO:K08854,ENOG410Y515^associated kinase,.,NA,NA,NA,NA,,
yes,AD,BMP,DN277006_c0_g1_i1,DN277006_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,.,NA,NA,NA,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN250071_c0_g1_i1,DN250071_c0_g1,BMP6_HUMAN,Bone morphogenetic protein 6,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0031982^cellular_component^vesicle,GO:0070700^molecular_function^BMP receptor binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:hsa:654`KO:K16620,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,BMP,DN223719_c0_g1_i1,DN223719_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN222391_c0_g1_i1,DN222391_c0_g1,BMP2A_XENLA,Bone morphogenetic protein 2-A,BMP2A_XENLA,Bone morphogenetic protein 2-A,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0051216^biological_process^cartilage development,GO:0030154^biological_process^cell differentiation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0051216^biological_process^cartilage development,GO:0030154^biological_process^cell differentiation,.,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^2-108^E:7e-23,PF00019.20^TGF_beta^Transforming growth factor beta like domain^195-297^E:4.9e-33,NA,NA,NA,,
yes,AD,BMP,DN208291_c0_g1_i1,DN208291_c0_g1,BMPR2_MOUSE,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:mmu:12168`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN314058_c0_g1_i1,DN314058_c0_g1,BMPR2_HUMAN,Bone morphogenetic protein receptor type-2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0005901^cellular_component^caveola,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,.,NA,NA,NA,NA,KEGG:hsa:659`KO:K04671,ENOG410XS2Z^transmembrane receptor protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
yes,AD,BMP,DN336590_c0_g1_i1,DN336590_c0_g1,BMP2K_MOUSE,BMP-2-inducible protein kinase,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0019208^molecular_function^phosphatase regulator activity,GO:0004672^molecular_function^protein kinase activity,.,NA,NA,NA,NA,KEGG:mmu:140780`KO:K08854,ENOG410Y515^associated kinase,.,NA,NA,NA,NA,,
yes,AD,BMP,DN393501_c0_g1_i1,DN393501_c0_g1,CRIM1_CHICK,Cysteine-rich motor neuron 1 protein,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0004867^molecular_function^serine-type endopeptidase inhibitor activity,NA,.,NA,NA,NA,NA,KEGG:gga:395067,ENOG410Z6K0^Cysteine rich transmembrane BMP regulator 1,.,NA,NA,NA,NA,,
yes,AD,BMP,DN431887_c0_g1_i1,DN431887_c0_g1,BRNP1_CHICK,BMP/retinoic acid-inducible neural-specific protein 1,BRNP1_CHICK,BMP/retinoic acid-inducible neural-specific protein 1,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0043025^cellular_component^neuronal cell body,GO:0001662^biological_process^behavioral fear response,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0005783^cellular_component^endoplasmic reticulum,GO:0043025^cellular_component^neuronal cell body,GO:0001662^biological_process^behavioral fear response,KEGG:gga:395098,"ENOG410XQ74^family with sequence similarity 5, member",PF01823.19^MACPF^MAC/Perforin domain^92-159^E:1.4e-06,NA,NA,NA,NA,,
yes,AD,BMP,DN429041_c0_g1_i1,DN429041_c0_g1,BMPER_MOUSE,BMP-binding endothelial regulator protein,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0002043^biological_process^blood vessel endothelial cell proliferation involved in sprouting angiogenesis,GO:0042118^biological_process^endothelial cell activation,.,NA,NA,NA,NA,KEGG:mmu:73230,ENOG410XW0S^BMP binding endothelial regulator,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN28726_c0_g1_i12,DN28726_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN28726_c0_g1_i8,DN28726_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:153579`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN28726_c0_g1_i4,DN28726_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN28726_c0_g1_i2,DN28726_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,BTNLA_MOUSE,Butyrophilin-like protein 10,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN28726_c0_g1_i7,DN28726_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN4_c3_g1_i10,DN4_c3_g1,.,NA,BTNL8_HUMAN,Butyrophilin-like protein 8,.,NA,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0002250^biological_process^adaptive immune response,KEGG:hsa:79908`KO:K06712,ENOG411140Z^Butyrophilin-like,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN4_c3_g1_i4,DN4_c3_g1,.,NA,BTNL8_HUMAN,Butyrophilin-like protein 8,.,NA,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0002250^biological_process^adaptive immune response,KEGG:hsa:79908`KO:K06712,ENOG411140Z^Butyrophilin-like,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN16397_c0_g2_i3,DN16397_c0_g2,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN839_c0_g2_i3,DN839_c0_g2,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF07686.17^V-set^Immunoglobulin V-set domain^7-111^E:2.4e-11,PF00047.25^ig^Immunoglobulin domain^8-109^E:2.4e-07,PF00622.28^SPRY^SPRY domain^343-447^E:4.1e-08,NA,NA,,
yes,AD,BTNL,DN839_c0_g2_i7,DN839_c0_g2,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN25957_c0_g1_i5,DN25957_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN25957_c0_g1_i1,DN25957_c0_g1,BTNL3_HUMAN,Butyrophilin-like protein 3,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:10917`KO:K06712,ENOG411140Z^Butyrophilin-like,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN26449_c0_g1_i2,DN26449_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,.,NA,NA,NA,NA,KEGG:mmu:100038862`KO:K06712,ENOG411153B^Butyrophilin-like protein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN17372_c0_g2_i5,DN17372_c0_g2,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN51832_c0_g1_i1,DN51832_c0_g1,BTNL2_RAT,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,.,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN51832_c0_g1_i7,DN51832_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN33817_c0_g1_i2,DN33817_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN12236_c0_g1_i2,DN12236_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN12236_c0_g1_i3,DN12236_c0_g1,BTNL8_HUMAN,Butyrophilin-like protein 8,SKIT4_MOUSE,Selection and upkeep of intraepithelial T-cells protein 4,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0002250^biological_process^adaptive immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:320640,ENOG4111DQZ^selection and upkeep of intraepithelial T cells,PF07686.17^V-set^Immunoglobulin V-set domain^32-91^E:4.2e-07,NA,NA,NA,NA,,
yes,AD,BTNL,DN12236_c0_g1_i14,DN12236_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,BT3A2_HUMAN,Butyrophilin subfamily 3 member A2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,KEGG:hsa:11118`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF13927.6^Ig_3^Immunoglobulin domain^30-123^E:3.7e-07,PF07686.17^V-set^Immunoglobulin V-set domain^32-138^E:1.6e-14,NA,NA,NA,,
yes,AD,BTNL,DN12236_c0_g1_i1,DN12236_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,BT2A1_HUMAN,Butyrophilin subfamily 2 member A1,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0006629^biological_process^lipid metabolic process,KEGG:hsa:11120`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF07686.17^V-set^Immunoglobulin V-set domain^32-91^E:6.1e-07,NA,NA,NA,NA,,
yes,AD,BTNL,DN12236_c0_g1_i10,DN12236_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,MOG_MACFA,Myelin-oligodendrocyte glycoprotein,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0007155^biological_process^cell adhesion,NA,NA,NA,KEGG:mcf:102118842`KO:K17270,ENOG4111A80^butyrophilin-like 10,PF07686.17^V-set^Immunoglobulin V-set domain^32-93^E:1.4e-06,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i15,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,BT3A3_PONAB,Butyrophilin subfamily 3 member A3,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:pon:100172913`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i6,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,.,NA,NA,NA,NA,KEGG:mmu:100038862`KO:K06712,ENOG411153B^Butyrophilin-like protein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i11,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,.,NA,NA,NA,NA,KEGG:mmu:100038862`KO:K06712,ENOG411153B^Butyrophilin-like protein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i3,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,.,NA,NA,NA,NA,KEGG:mmu:100038862`KO:K06712,ENOG411153B^Butyrophilin-like protein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i8,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,BT3A3_HUMAN,Butyrophilin subfamily 3 member A3,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,KEGG:hsa:10384`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i4,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,BT3A3_PONAB,Butyrophilin subfamily 3 member A3,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:pon:100172913`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7794_c0_g1_i1,DN7794_c0_g1,BTNL1_MOUSE,Butyrophilin-like protein 1,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0045062^biological_process^extrathymic T cell selection,.,NA,NA,NA,NA,KEGG:mmu:100038862`KO:K06712,ENOG411153B^Butyrophilin-like protein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN4145_c0_g1_i11,DN4145_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,BTNL2_HUMAN,Butyrophilin-like protein 2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF13927.6^Ig_3^Immunoglobulin domain^12-104^E:6.2e-08,PF07679.16^I-set^Immunoglobulin I-set domain^12-119^E:1.8e-06,PF07686.17^V-set^Immunoglobulin V-set domain^14-119^E:3.7e-17,NA,NA,,
yes,AD,BTNL,DN9980_c1_g1_i2,DN9980_c1_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN9002_c0_g1_i8,DN9002_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:153579`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN9002_c0_g1_i10,DN9002_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,BTNL9_HUMAN,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:153579`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN10267_c0_g1_i5,DN10267_c0_g1,BTNL2_MOUSE,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,.,NA,NA,NA,NA,KEGG:mmu:547431,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN10267_c0_g1_i12,DN10267_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,BTNL2_HUMAN,Butyrophilin-like protein 2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN10267_c0_g1_i11,DN10267_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,BTNLA_MOUSE,Butyrophilin-like protein 10,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,PF07686.17^V-set^Immunoglobulin V-set domain^46-105^E:1.8e-06,NA,NA,NA,NA,,
yes,AD,BTNL,DN10267_c0_g1_i2,DN10267_c0_g1,BTNLA_MOUSE,Butyrophilin-like protein 10,BTNLA_MOUSE,Butyrophilin-like protein 10,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:192194,ENOG4111A80^butyrophilin-like 10,PF07686.17^V-set^Immunoglobulin V-set domain^48-105^E:3.2e-06,NA,NA,NA,NA,,
yes,AD,BTNL,DN10267_c0_g1_i9,DN10267_c0_g1,BTNL2_MOUSE,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,.,NA,NA,NA,NA,KEGG:mmu:547431,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN10222_c0_g1_i5,DN10222_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN7514_c0_g1_i5,DN7514_c0_g1,PD1L1_MOUSE,Programmed cell death 1 ligand 1,BTNL8_HUMAN,Butyrophilin-like protein 8,GO:0009986^cellular_component^cell surface,GO:0031901^cellular_component^early endosome membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0002250^biological_process^adaptive immune response,KEGG:hsa:79908`KO:K06712,ENOG411140Z^Butyrophilin-like,PF07686.17^V-set^Immunoglobulin V-set domain^26-133^E:2.2e-12,NA,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i2,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF08205.12^C2-set_2^CD80-like C2-set immunoglobulin domain^6-85^E:0.00011,PF07654.15^C1-set^Immunoglobulin C1-set domain^14-81^E:0.0001,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i1,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF08205.12^C2-set_2^CD80-like C2-set immunoglobulin domain^6-85^E:0.00012,PF07654.15^C1-set^Immunoglobulin C1-set domain^14-81^E:0.00011,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i16,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF07654.15^C1-set^Immunoglobulin C1-set domain^3-68^E:0.00016,NA,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i9,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF08205.12^C2-set_2^CD80-like C2-set immunoglobulin domain^6-85^E:9.4e-05,PF07654.15^C1-set^Immunoglobulin C1-set domain^14-81^E:9.3e-05,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i13,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF07654.15^C1-set^Immunoglobulin C1-set domain^3-68^E:0.00016,NA,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i14,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i12,DN5713_c0_g1,BT3A2_HUMAN,Butyrophilin subfamily 3 member A2,BTNL9_MOUSE,Butyrophilin-like protein 9,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF08205.12^C2-set_2^CD80-like C2-set immunoglobulin domain^42-121^E:0.00012,PF07654.15^C1-set^Immunoglobulin C1-set domain^50-117^E:0.00012,NA,NA,NA,,
yes,AD,BTNL,DN5713_c0_g1_i3,DN5713_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,BT3A2_HUMAN,Butyrophilin subfamily 3 member A2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,KEGG:hsa:11118`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",PF13927.6^Ig_3^Immunoglobulin domain^30-128^E:5e-10,PF07686.17^V-set^Immunoglobulin V-set domain^35-133^E:2.8e-13,PF07679.16^I-set^Immunoglobulin I-set domain^37-141^E:4.7e-06,PF00047.25^ig^Immunoglobulin domain^41-132^E:2e-07,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^45-146^E:6.2e-07,,
yes,AD,BTNL,DN37925_c0_g1_i1,DN37925_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:153579`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN9730_c0_g1_i1,DN9730_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN9730_c0_g1_i11,DN9730_c0_g1,MOG_PONAB,Myelin-oligodendrocyte glycoprotein,BTNL2_HUMAN,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0007155^biological_process^cell adhesion,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07686.17^V-set^Immunoglobulin V-set domain^28-110^E:3.1e-09,NA,NA,NA,NA,,
yes,AD,BTNL,DN551_c0_g3_i1,DN551_c0_g3,.,NA,BTNL8_HUMAN,Butyrophilin-like protein 8,.,NA,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0002250^biological_process^adaptive immune response,KEGG:hsa:79908`KO:K06712,ENOG411140Z^Butyrophilin-like,PF07686.17^V-set^Immunoglobulin V-set domain^13-69^E:3.8e-07,NA,NA,NA,NA,,
yes,AD,BTNL,DN8846_c1_g1_i3,DN8846_c1_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN16441_c1_g1_i1,DN16441_c1_g1,BTNL3_HUMAN,Butyrophilin-like protein 3,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:10917`KO:K06712,ENOG411140Z^Butyrophilin-like,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN4657_c0_g1_i10,DN4657_c0_g1,BT2A2_HUMAN,Butyrophilin subfamily 2 member A2,BTNL2_HUMAN,Butyrophilin-like protein 2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN18614_c0_g1_i8,DN18614_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,BTNL2_HUMAN,Butyrophilin-like protein 2,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07686.17^V-set^Immunoglobulin V-set domain^40-127^E:7.3e-12,NA,NA,NA,NA,,
yes,AD,BTNL,DN31670_c0_g1_i6,DN31670_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,MOG_RAT,Myelin-oligodendrocyte glycoprotein,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,GO:0043209^cellular_component^myelin sheath,KEGG:hsa:56244,ENOG41119UE^Myelin oligodendrocyte glycoprotein,.,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c0_g1_i4,DN73246_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c0_g1_i7,DN73246_c0_g1,BTNL2_MOUSE,Butyrophilin-like protein 2,MOG_PONAB,Myelin-oligodendrocyte glycoprotein,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,GO:0016021^cellular_component^integral component of membrane,GO:0007155^biological_process^cell adhesion,NA,NA,NA,KEGG:pon:100172932`KO:K17270,ENOG41119UE^Myelin oligodendrocyte glycoprotein,PF07686.17^V-set^Immunoglobulin V-set domain^34-122^E:1.9e-12,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c0_g1_i2,DN73246_c0_g1,BTNL2_MOUSE,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,.,NA,NA,NA,NA,KEGG:mmu:547431,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c0_g1_i5,DN73246_c0_g1,BTNL2_MOUSE,Butyrophilin-like protein 2,MOG_PONAB,Myelin-oligodendrocyte glycoprotein,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,GO:0016021^cellular_component^integral component of membrane,GO:0007155^biological_process^cell adhesion,NA,NA,NA,KEGG:pon:100172932`KO:K17270,ENOG41119UE^Myelin oligodendrocyte glycoprotein,PF07686.17^V-set^Immunoglobulin V-set domain^37-125^E:1.1e-12,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c0_g1_i3,DN73246_c0_g1,BTNL2_HUMAN,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:56244,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN73246_c1_g2_i1,DN73246_c1_g2,BTNL2_MOUSE,Butyrophilin-like protein 2,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050860^biological_process^negative regulation of T cell receptor signaling pathway,GO:1900042^biological_process^positive regulation of interleukin-2 secretion,.,NA,NA,NA,NA,KEGG:mmu:547431,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),.,NA,NA,NA,NA,,
yes,AD,BTNL,DN721_c0_g1_i18,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.2e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.4e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.3e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i17,DN721_c0_g1,MEFV_HUMAN,Pyrin,BTNL2_RAT,Butyrophilin-like protein 2,GO:0005776^cellular_component^autophagosome,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0030027^cellular_component^lamellipodium,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:hsa:4210`KO:K12803,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.2e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.4e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.3e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i27,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.3e-07,PF13895.6^Ig_2^Immunoglobulin domain^85-183^E:4.4e-06,PF00047.25^ig^Immunoglobulin domain^92-186^E:5.5e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:5.7e-08,,
yes,AD,BTNL,DN721_c0_g1_i9,DN721_c0_g1,MEFV_HUMAN,Pyrin,BTNL2_RAT,Butyrophilin-like protein 2,GO:0005776^cellular_component^autophagosome,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0030027^cellular_component^lamellipodium,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:hsa:4210`KO:K12803,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.2e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.4e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.3e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i5,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.4e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.5e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6.4e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.8e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i3,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.4e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.5e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6.4e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.8e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i30,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.5e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.7e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6.9e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:7.3e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i29,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.4e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.5e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:6.4e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:6.8e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i16,DN721_c0_g1,MEFV_HUMAN,Pyrin,BTNL2_RAT,Butyrophilin-like protein 2,GO:0005776^cellular_component^autophagosome,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0030027^cellular_component^lamellipodium,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:hsa:4210`KO:K12803,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:2.6e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.7e-07,PF00047.25^ig^Immunoglobulin domain^92-186^E:7e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:7.4e-08,NA,,
yes,AD,BTNL,DN721_c0_g1_i21,DN721_c0_g1,BT2A2_PONAB,Butyrophilin subfamily 2 member A2,BTNL2_RAT,Butyrophilin-like protein 2,GO:0016021^cellular_component^integral component of membrane,GO:0046007^biological_process^negative regulation of activated T cell proliferation,GO:0031324^biological_process^negative regulation of cellular metabolic process,GO:0050710^biological_process^negative regulation of cytokine secretion,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,KEGG:pon:100173224`KO:K06712,ENOG410YIB9^Butyrophilin-like 2 (MHC class II associated),PF07679.16^I-set^Immunoglobulin I-set domain^84-192^E:1.8e-08,PF13927.6^Ig_3^Immunoglobulin domain^85-178^E:1.2e-07,PF13895.6^Ig_2^Immunoglobulin domain^85-183^E:4e-06,PF00047.25^ig^Immunoglobulin domain^92-186^E:5e-07,PF07686.17^V-set^Immunoglobulin V-set domain^93-193^E:5.2e-08,,
yes,AD,BTNL,DN238585_c0_g1_i1,DN238585_c0_g1,BTNL9_HUMAN,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:hsa:153579`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,BTNL,DN371219_c0_g1_i1,DN371219_c0_g1,BTNL9_MOUSE,Butyrophilin-like protein 9,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005102^molecular_function^signaling receptor binding,GO:0050776^biological_process^regulation of immune response,GO:0050852^biological_process^T cell receptor signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:237754`KO:K06712,"ENOG410YA6W^butyrophilin, subfamily",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN5630_c0_g1_i3,DN5630_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN53256_c0_g1_i3,DN53256_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN61416_c0_g1_i1,DN61416_c0_g1,PDE4A_CAVPO,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0016787^molecular_function^hydrolase activity,GO:0006198^biological_process^cAMP catabolic process,NA,NA,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN61416_c0_g1_i2,DN61416_c0_g1,PDE4A_CAVPO,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0016787^molecular_function^hydrolase activity,GO:0006198^biological_process^cAMP catabolic process,NA,NA,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN498_c1_g2_i1,DN498_c1_g2,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,PF02827.16^PKI^cAMP-dependent protein kinase inhibitor^32-97^E:1.4e-23,NA,NA,NA,NA,,
yes,AD,CAMP,DN498_c1_g2_i5,DN498_c1_g2,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN498_c1_g2_i3,DN498_c1_g2,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN498_c1_g2_i6,DN498_c1_g2,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN498_c1_g2_i10,DN498_c1_g2,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN42543_c0_g1_i1,DN42543_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,KEGG:hsa:57662`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i8,DN24524_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i5,DN24524_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i6,DN24524_c0_g1,.,NA,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},.,NA,NA,NA,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i10,DN24524_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i17,DN24524_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN24524_c0_g1_i7,DN24524_c0_g1,CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN66045_c0_g1_i1,DN66045_c0_g1,ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN15466_c0_g1_i2,DN15466_c0_g1,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,.,NA,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,.,NA,NA,NA,NA,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN15466_c0_g1_i7,DN15466_c0_g1,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,.,NA,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,.,NA,NA,NA,NA,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN15466_c0_g1_i4,DN15466_c0_g1,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,.,NA,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,.,NA,NA,NA,NA,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN99794_c0_g1_i1,DN99794_c0_g1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,.,NA,NA,NA,NA,KEGG:bta:281713`KO:K05870,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN57108_c0_g1_i1,DN57108_c0_g1,ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:55902`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN5134_c0_g1_i2,DN5134_c0_g1,ADPRM_MOUSE,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,ADPRM_BOVIN,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,KEGG:mmu:66358`KO:K01517,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^9-269^E:4.7e-11,NA,NA,NA,NA,,
yes,AD,CAMP,DN5134_c0_g1_i1,DN5134_c0_g1,ADPRM_RAT,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,ADPRM_BOVIN,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,KEGG:rno:287406`KO:K01517,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^9-118^E:1e-06,NA,NA,NA,NA,,
yes,AD,CAMP,DN5134_c0_g1_i3,DN5134_c0_g1,ADPRM_RAT,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,ADPRM_RAT,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,KEGG:rno:287406`KO:K01517,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i6,DN4244_c0_g1,IPKG_BOVIN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:bta:404169,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i2,DN4244_c0_g1,IPKG_HUMAN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0042308^biological_process^negative regulation of protein import into nucleus,.,NA,NA,NA,NA,KEGG:hsa:11142,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i12,DN4244_c0_g1,IPKG_BOVIN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:bta:404169,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i10,DN4244_c0_g1,IPKG_BOVIN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:bta:404169,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i4,DN4244_c0_g1,IPKG_BOVIN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:bta:404169,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4244_c0_g1_i5,DN4244_c0_g1,IPKG_HUMAN,cAMP-dependent protein kinase inhibitor gamma,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0042308^biological_process^negative regulation of protein import into nucleus,.,NA,NA,NA,NA,KEGG:hsa:11142,"ENOG410ZDGT^Protein kinase (CAMP-dependent, catalytic) inhibitor gamma",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13959_c0_g2_i6,DN13959_c0_g2,IPKA_CHICK,cAMP-dependent protein kinase inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:gga:396333`KO:K15985,"ENOG410YT4B^Protein kinase (CAMP-dependent, catalytic) inhibitor alpha",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13959_c0_g2_i7,DN13959_c0_g2,IPKA_CHICK,cAMP-dependent protein kinase inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:gga:396333`KO:K15985,"ENOG410YT4B^Protein kinase (CAMP-dependent, catalytic) inhibitor alpha",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13959_c0_g2_i1,DN13959_c0_g2,IPKA_CHICK,cAMP-dependent protein kinase inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:gga:396333`KO:K15985,"ENOG410YT4B^Protein kinase (CAMP-dependent, catalytic) inhibitor alpha",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13959_c0_g2_i4,DN13959_c0_g2,IPKA_CHICK,cAMP-dependent protein kinase inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,NA,.,NA,NA,NA,NA,KEGG:gga:396333`KO:K15985,"ENOG410YT4B^Protein kinase (CAMP-dependent, catalytic) inhibitor alpha",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN29149_c0_g1_i1,DN29149_c0_g1,KAP3_HUMAN,cAMP-dependent protein kinase type II-beta regulatory subunit,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:5577`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN5430_c4_g1_i2,DN5430_c4_g1,ARP19_CHICK,cAMP-regulated phosphoprotein 19,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0015459^molecular_function^potassium channel regulator activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:768853,ENOG4112586^CAMP-regulated phosphoprotein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3667_c2_g1_i2,DN3667_c2_g1,CR3L4_MACFA,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3667_c2_g1_i4,DN3667_c2_g1,CR3L4_MACFA,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN2738_c1_g1_i2,DN2738_c1_g1,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,.,NA,NA,NA,NA,KEGG:hsa:5575`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN57756_c0_g1_i3,DN57756_c0_g1,ACSA_BARHE,Acetyl-coenzyme A synthetase {ECO:0000255|HAMAP-Rule:MF_01123},ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0019427^biological_process^acetyl-CoA biosynthetic process from acetate,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN57756_c0_g1_i5,DN57756_c0_g1,ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i5,DN32375_c0_g1,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^70-477^E:8.2e-82,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^486-553^E:3.7e-15,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i4,DN32375_c0_g1,ACSM3_RAT,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^11-152^E:6.7e-36,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^161-241^E:1.4e-24,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i10,DN32375_c0_g1,ACSM4_RAT,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",ACSM4_MOUSE,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:233801`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^66-245^E:2.7e-30,NA,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i6,DN32375_c0_g1,ACSM4_MOUSE,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",ACSM4_MOUSE,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:233801`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^66-245^E:2.7e-30,NA,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i12,DN32375_c0_g1,ACSM3_RAT,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_RAT,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,KEGG:rno:24763`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^12-175^E:5.6e-40,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^184-209^E:1.2e-06,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i9,DN32375_c0_g1,ACSM4_MOUSE,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",ACSM4_MOUSE,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:233801`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^66-476^E:1.3e-78,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^485-565^E:5.8e-24,NA,NA,NA,,
yes,AD,CAMP,DN32375_c0_g1_i2,DN32375_c0_g1,ACSM4_RAT,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:rno:353317`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN32314_c0_g1_i1,DN32314_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i5,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^207-278^E:0.00028,PF00170.21^bZIP_1^bZIP transcription factor^212-274^E:3.3e-12,PF07716.15^bZIP_2^Basic region leucine zipper^216-266^E:2e-08,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i7,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i16,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^46-108^E:1.7e-12,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^48-112^E:0.00044,PF07716.15^bZIP_2^Basic region leucine zipper^50-100^E:1e-08,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i12,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^3-36^E:2.5e-09,PF07716.15^bZIP_2^Basic region leucine zipper^7-36^E:2.9e-05,NA,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i11,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^135-206^E:8.3e-05,PF00170.21^bZIP_1^bZIP transcription factor^140-202^E:3.1e-12,PF07716.15^bZIP_2^Basic region leucine zipper^144-194^E:1.5e-08,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i6,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^207-278^E:0.00029,PF00170.21^bZIP_1^bZIP transcription factor^212-274^E:3.3e-12,PF07716.15^bZIP_2^Basic region leucine zipper^216-266^E:2.1e-08,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i14,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3LB_DANRE,Cyclic AMP-responsive element-binding protein 3-like protein 3-B,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^3-36^E:3.6e-09,PF07716.15^bZIP_2^Basic region leucine zipper^7-36^E:4.1e-05,NA,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i10,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3LB_DANRE,Cyclic AMP-responsive element-binding protein 3-like protein 3-B,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^3-36^E:1.7e-08,NA,NA,NA,NA,,
yes,AD,CAMP,DN14258_c0_g1_i8,DN14258_c0_g1,CR3L3_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 3,CR3LB_DANRE,Cyclic AMP-responsive element-binding protein 3-like protein 3-B,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:hsa:84699`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^3-36^E:1.7e-08,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c0_g3_i4,DN283_c0_g3,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,KEGG:hsa:5575`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^95-131^E:7.2e-14,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c0_g3_i2,DN283_c0_g3,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,.,NA,NA,NA,NA,KEGG:hsa:5575`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c0_g3_i3,DN283_c0_g3,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,KAP1_HUMAN,cAMP-dependent protein kinase type I-beta regulatory subunit,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,KEGG:hsa:5575`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^95-131^E:1.8e-13,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^230-306^E:5.6e-19,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^344-429^E:3.8e-20,NA,NA,,
yes,AD,CAMP,DN283_c1_g1_i1,DN283_c1_g1,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^25-61^E:7.1e-15,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c1_g2_i1,DN283_c1_g2,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^44-124^E:3.3e-19,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c1_g2_i2,DN283_c1_g2,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^18-103^E:1.8e-20,NA,NA,NA,NA,,
yes,AD,CAMP,DN283_c1_g2_i3,DN283_c1_g2,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^44-124^E:2.1e-19,NA,NA,NA,NA,,
yes,AD,CAMP,DN38838_c0_g1_i1,DN38838_c0_g1,PDE7A_RAT,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0019933^biological_process^cAMP-mediated signaling,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN38838_c0_g1_i3,DN38838_c0_g1,PDE7A_MOUSE,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,.,NA,NA,NA,NA,KEGG:mmu:18583`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN38838_c0_g1_i4,DN38838_c0_g1,PDE7A_MOUSE,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,.,NA,NA,NA,NA,KEGG:mmu:18583`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i28,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i19,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_MOUSE,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:mmu:74100,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^179-234^E:4.3e-12,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i14,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^179-234^E:5.4e-12,PF12752.7^SUZ^SUZ domain^259-312^E:2.5e-12,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i9,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,.,NA,NA,NA,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i23,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i27,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i2,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i30,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,.,NA,NA,NA,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i1,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,.,NA,NA,NA,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i21,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^179-234^E:5e-12,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i15,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i22,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^179-234^E:5e-12,NA,NA,NA,NA,,
yes,AD,CAMP,DN13410_c0_g1_i4,DN13410_c0_g1,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,ARP21_HUMAN,cAMP-regulated phosphoprotein 21,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,GO:0005737^cellular_component^cytoplasm,GO:0005516^molecular_function^calmodulin binding,GO:0003676^molecular_function^nucleic acid binding,GO:0034605^biological_process^cellular response to heat,NA,KEGG:hsa:10777,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^179-234^E:2.4e-12,PF12752.7^SUZ^SUZ domain^259-310^E:1.8e-12,NA,NA,NA,,
yes,AD,CAMP,DN88791_c0_g1_i1,DN88791_c0_g1,PDE7B_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,NA,.,NA,NA,NA,NA,KEGG:mmu:29863`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN88791_c0_g1_i2,DN88791_c0_g1,PDE7B_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,NA,.,NA,NA,NA,NA,KEGG:mmu:29863`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN4024_c0_g1_i5,DN4024_c0_g1,R3HD2_BOVIN,R3H domain-containing protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:613499,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i3,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,AACS_CHICK,Acetoacetyl-CoA synthetase,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^96-153^E:4.1e-10,PF00501.28^AMP-binding^AMP-binding enzyme^158-238^E:2.6e-12,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i8,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,AACS_CHICK,Acetoacetyl-CoA synthetase,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^1-207^E:4.8e-19,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i5,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,AACS_CHICK,Acetoacetyl-CoA synthetase,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^9-354^E:3.6e-26,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i4,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i9,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i7,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g1_i2,DN4005_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,AACS_CHICK,Acetoacetyl-CoA synthetase,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^30-411^E:4e-41,NA,NA,NA,NA,,
no,AD,CAMP,DN4005_c0_g2_i1,DN4005_c0_g2,AACS_CHICK,Acetoacetyl-CoA synthetase,AACS_CHICK,Acetoacetyl-CoA synthetase,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i5,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",PF11971.8^CAMSAP_CH^CAMSAP CH domain^11-89^E:3.4e-36,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^523-574^E:6.9e-25,NA,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i8,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^193-311^E:5.5e-55,NA,NA,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i10,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_MOUSE,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0036449^cellular_component^microtubule minus-end,GO:0005516^molecular_function^calmodulin binding,KEGG:mmu:67886`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^1-79^E:2.5e-33,NA,NA,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i9,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",PF11971.8^CAMSAP_CH^CAMSAP CH domain^110-188^E:5.1e-36,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^622-673^E:1e-24,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^1222-1340^E:5.4e-54,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i2,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i7,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",PF11971.8^CAMSAP_CH^CAMSAP CH domain^226-304^E:5.2e-36,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^738-789^E:1e-24,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^1338-1376^E:3.6e-13,NA,NA,,
no,AD,CAMP,DN4083_c0_g1_i4,DN4083_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
no,AD,CAMP,DN699_c1_g1_i2,DN699_c1_g1,KGP2_RAT,cGMP-dependent protein kinase 2,KGP2_RAT,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,KEGG:rno:25523`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-247^E:7.6e-66,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^8-230^E:2.9e-30,NA,NA,NA,,
no,AD,CAMP,DN699_c1_g1_i1,DN699_c1_g1,KGP2_RAT,cGMP-dependent protein kinase 2,KGP2_RAT,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,KEGG:rno:25523`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-247^E:7.6e-66,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^8-230^E:2.9e-30,NA,NA,NA,,
no,AD,CAMP,DN699_c1_g1_i5,DN699_c1_g1,KGP2_RAT,cGMP-dependent protein kinase 2,KGP2_RAT,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0031965^cellular_component^nuclear membrane,KEGG:rno:25523`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-247^E:7.6e-66,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^8-230^E:2.9e-30,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i1,DN601_c0_g1,PDE4A_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:18577`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i4,DN601_c0_g1,PDE4A_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:18577`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i6,DN601_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^1-179^E:2.1e-64,NA,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i2,DN601_c0_g1,PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^116-233^E:4.9e-55,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^357-598^E:3.4e-95,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i5,DN601_c0_g1,PDE4A_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",PDE4A_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:5141`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^106-223^E:3e-55,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^347-456^E:3.8e-45,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g1_i7,DN601_c0_g1,PDE4A_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:5141`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g2_i1,DN601_c0_g2,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^102-175^E:2.6e-38,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^297-538^E:2.3e-92,NA,NA,NA,,
yes,AD,CAMP,DN601_c0_g3_i1,DN601_c0_g3,PDE4B_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",PDE4B_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",KEGG:rno:24626`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^46-125^E:3.4e-39,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^249-490^E:1.5e-93,NA,NA,NA,,
yes,AD,CAMP,DN3197_c0_g1_i3,DN3197_c0_g1,FICD_HUMAN,Protein adenylyltransferase FICD {ECO:0000305},.,NA,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0005524^molecular_function^ATP binding,GO:0051087^molecular_function^chaperone binding,GO:0030544^molecular_function^Hsp70 protein binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:hsa:11153,COG3177^Filamentation induced by cAMP protein fic,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN45211_c0_g1_i1,DN45211_c0_g1,PDE7A_MOUSE,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,.,NA,NA,NA,NA,KEGG:mmu:18583`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN7924_c0_g1_i6,DN7924_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^37-155^E:5.7e-56,NA,NA,NA,NA,,
no,AD,CAMP,DN7924_c0_g1_i2,DN7924_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^231-312^E:2e-34,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^873-927^E:8e-24,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^1471-1589^E:3.5e-54,NA,NA,,
no,AD,CAMP,DN7924_c0_g1_i7,DN7924_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^8-89^E:4.4e-35,NA,NA,NA,NA,,
no,AD,CAMP,DN7924_c0_g1_i1,DN7924_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^231-312^E:1.6e-34,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^873-927^E:6.4e-24,NA,NA,NA,,
no,AD,CAMP,DN7924_c0_g1_i3,DN7924_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN77081_c0_g1_i1,DN77081_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN10009_c0_g1_i5,DN10009_c0_g1,ENSA_PIG,Alpha-endosulfine,ENSA_CHICK,Alpha-endosulfine,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0019888^molecular_function^protein phosphatase regulator activity,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0019870^molecular_function^potassium channel inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,KEGG:gga:425073,ENOG4112586^CAMP-regulated phosphoprotein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN10009_c0_g1_i1,DN10009_c0_g1,ENSA_PIG,Alpha-endosulfine,ENSA_CHICK,Alpha-endosulfine,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0019888^molecular_function^protein phosphatase regulator activity,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0019870^molecular_function^potassium channel inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,KEGG:gga:425073,ENOG4112586^CAMP-regulated phosphoprotein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN10009_c0_g1_i7,DN10009_c0_g1,ENSA_PIG,Alpha-endosulfine,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0019888^molecular_function^protein phosphatase regulator activity,.,NA,NA,NA,NA,.,ENOG4112586^CAMP-regulated phosphoprotein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN76122_c1_g1_i2,DN76122_c1_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN76182_c0_g1_i2,DN76182_c0_g1,PDE4A_CAVPO,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0016787^molecular_function^hydrolase activity,GO:0006198^biological_process^cAMP catabolic process,NA,NA,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN76182_c0_g1_i1,DN76182_c0_g1,PDE4A_CAVPO,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0016787^molecular_function^hydrolase activity,GO:0006198^biological_process^cAMP catabolic process,NA,NA,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN5230_c1_g1_i1,DN5230_c1_g1,ARP19_PIG,cAMP-regulated phosphoprotein 19,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0019212^molecular_function^phosphatase inhibitor activity,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0019888^molecular_function^protein phosphatase regulator activity,.,NA,NA,NA,NA,KEGG:ssc:397362,ENOG4112586^CAMP-regulated phosphoprotein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN3468_c0_g1_i15,DN3468_c0_g1,ADPRM_RAT,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,ADPRM_MOUSE,Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,GO:0047631^molecular_function^ADP-ribose diphosphatase activity,GO:0047734^molecular_function^CDP-glycerol diphosphatase activity,GO:0046872^molecular_function^metal ion binding,NA,NA,KEGG:mmu:66358`KO:K01517,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i3,DN2528_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i8,DN2528_c0_g1,KGP25_DROME,"cGMP-dependent protein kinase, isozyme 2 forms cD5/T2",KGP1_MOUSE,cGMP-dependent protein kinase 1,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0001669^cellular_component^acrosomal vesicle,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,KEGG:mmu:19091`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^4-51^E:3.3e-10,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^92-174^E:2.1e-23,PF00069.25^Pkinase^Protein kinase domain^234-470^E:1.4e-61,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^234-439^E:5e-30,PF14531.6^Kinase-like^Kinase-like^339-434^E:2.1e-06,,
no,AD,CAMP,DN2528_c0_g1_i13,DN2528_c0_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,.,NA,NA,NA,NA,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i10,DN2528_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i4,DN2528_c0_g1,KGP1_MOUSE,cGMP-dependent protein kinase 1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",GO:0001669^cellular_component^acrosomal vesicle,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-127^E:5.8e-27,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^1-84^E:3.1e-10,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i7,DN2528_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^5-87^E:1.3e-23,PF00069.25^Pkinase^Protein kinase domain^147-396^E:1.7e-64,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^147-353^E:1.5e-30,PF14531.6^Kinase-like^Kinase-like^252-348^E:9e-07,NA,,
no,AD,CAMP,DN2528_c0_g1_i1,DN2528_c0_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^71-320^E:9.8e-65,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^71-277^E:9.1e-31,PF14531.6^Kinase-like^Kinase-like^176-272^E:6.2e-07,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i9,DN2528_c0_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-127^E:5.8e-27,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^1-84^E:3.1e-10,NA,NA,NA,,
no,AD,CAMP,DN2528_c0_g1_i11,DN2528_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^28-192^E:3.1e-44,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^40-149^E:4e-19,PF14531.6^Kinase-like^Kinase-like^48-144^E:2.7e-07,NA,NA,,
no,AD,CAMP,DN2528_c0_g2_i3,DN2528_c0_g2,KGP1_MOUSE,cGMP-dependent protein kinase 1,KGP1_RABIT,cGMP-dependent protein kinase 1,GO:0001669^cellular_component^acrosomal vesicle,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005246^molecular_function^calcium channel regulator activity,GO:0030553^molecular_function^cGMP binding,GO:0004692^molecular_function^cGMP-dependent protein kinase activity,KEGG:ocu:100008694`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^104-164^E:1.2e-12,NA,NA,NA,NA,,
no,AD,CAMP,DN2528_c2_g1_i1,DN2528_c2_g1,KGP1_RABIT,cGMP-dependent protein kinase 1,KGP1_RABIT,cGMP-dependent protein kinase 1,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005246^molecular_function^calcium channel regulator activity,GO:0030553^molecular_function^cGMP binding,GO:0004692^molecular_function^cGMP-dependent protein kinase activity,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005246^molecular_function^calcium channel regulator activity,GO:0030553^molecular_function^cGMP binding,GO:0004692^molecular_function^cGMP-dependent protein kinase activity,KEGG:ocu:100008694`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN37708_c0_g1_i2,DN37708_c0_g1,KAP0_CHICK,cAMP-dependent protein kinase type I-alpha regulatory subunit,.,NA,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0098978^cellular_component^glutamatergic synapse,GO:0001772^cellular_component^immunological synapse,.,NA,NA,NA,NA,KEGG:gga:417438`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN36957_c0_g1_i1,DN36957_c0_g1,PDE4A_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:18577`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN10791_c0_g1_i5,DN10791_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN1906_c0_g1_i6,DN1906_c0_g1,ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,KEGG:mmu:68738`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^14-296^E:5e-62,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^305-383^E:1.5e-22,NA,NA,NA,,
no,AD,CAMP,DN1906_c0_g1_i4,DN1906_c0_g1,ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,KEGG:mmu:68738`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^74-128^E:1.6e-12,PF00501.28^AMP-binding^AMP-binding enzyme^130-569^E:2.6e-92,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^578-656^E:3.1e-22,NA,NA,,
yes,AD,CAMP,DN43275_c0_g1_i7,DN43275_c0_g1,PDE4C_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4C",.,NA,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:hsa:5143`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN43275_c0_g1_i4,DN43275_c0_g1,PDE4C_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4C",.,NA,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:hsa:5143`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN16178_c0_g1_i3,DN16178_c0_g1,PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,KEGG:hsa:5142`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^151-220^E:6.2e-25,NA,NA,NA,NA,,
yes,AD,CAMP,DN16178_c0_g1_i2,DN16178_c0_g1,PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,KEGG:hsa:5142`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN16178_c0_g1_i5,DN16178_c0_g1,PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",PDE4B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0060076^cellular_component^excitatory synapse,GO:0000930^cellular_component^gamma-tubulin complex,KEGG:hsa:5142`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^165-234^E:7e-25,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i11,DN13777_c0_g1,GBA2_MOUSE,Non-lysosomal glucosylceramidase {ECO:0000305},CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005829^cellular_component^cytosol,GO:0042406^cellular_component^extrinsic component of endoplasmic reticulum membrane,GO:0090498^cellular_component^extrinsic component of Golgi membrane,GO:0019898^cellular_component^extrinsic component of membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^29-90^E:8.3e-10,PF07716.15^bZIP_2^Basic region leucine zipper^40-82^E:5.7e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i24,DN13777_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i20,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^61-122^E:1.1e-09,PF07716.15^bZIP_2^Basic region leucine zipper^72-114^E:7.2e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i5,DN13777_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i19,DN13777_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i13,DN13777_c0_g1,GBA2_MOUSE,Non-lysosomal glucosylceramidase {ECO:0000305},CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005829^cellular_component^cytosol,GO:0042406^cellular_component^extrinsic component of endoplasmic reticulum membrane,GO:0090498^cellular_component^extrinsic component of Golgi membrane,GO:0019898^cellular_component^extrinsic component of membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^88-149^E:1.4e-09,PF07716.15^bZIP_2^Basic region leucine zipper^99-141^E:8.7e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i8,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^41-102^E:8.5e-10,PF07716.15^bZIP_2^Basic region leucine zipper^52-94^E:5.8e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i4,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i7,DN13777_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i18,DN13777_c0_g1,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_XENTR,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0035497^molecular_function^cAMP response element binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:xtr:780164`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^41-102^E:4.1e-09,PF07716.15^bZIP_2^Basic region leucine zipper^52-94^E:5.8e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i21,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i3,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^41-102^E:9.9e-10,PF07716.15^bZIP_2^Basic region leucine zipper^52-94^E:6.6e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i2,DN13777_c0_g1,GBA2_MOUSE,Non-lysosomal glucosylceramidase {ECO:0000305},CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005829^cellular_component^cytosol,GO:0042406^cellular_component^extrinsic component of endoplasmic reticulum membrane,GO:0090498^cellular_component^extrinsic component of Golgi membrane,GO:0019898^cellular_component^extrinsic component of membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^41-102^E:9.9e-10,PF07716.15^bZIP_2^Basic region leucine zipper^52-94^E:6.6e-06,NA,NA,NA,,
yes,AD,CAMP,DN13777_c0_g1_i22,DN13777_c0_g1,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,CR3L4_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:148327`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF00170.21^bZIP_1^bZIP transcription factor^61-122^E:1.1e-09,PF07716.15^bZIP_2^Basic region leucine zipper^72-114^E:7.1e-06,NA,NA,NA,,
yes,AD,CAMP,DN2337_c0_g1_i1,DN2337_c0_g1,ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:55902`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN2337_c0_g1_i12,DN2337_c0_g1,ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:55902`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN2337_c0_g1_i11,DN2337_c0_g1,ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:55902`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^40-99^E:9.6e-19,PF00501.28^AMP-binding^AMP-binding enzyme^108-567^E:2.8e-96,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^576-654^E:2e-24,NA,NA,,
yes,AD,CAMP,DN2337_c0_g1_i6,DN2337_c0_g1,ACSA_HUMAN,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:55902`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1457_c0_g1_i20,DN1457_c0_g1,R3HD1_HUMAN,R3H domain-containing protein 1,R3HD2_BOVIN,R3H domain-containing protein 2,GO:0003723^molecular_function^RNA binding,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,NA,NA,NA,KEGG:bta:613499,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",PF01424.22^R3H^R3H domain^69-125^E:1.7e-11,PF12752.7^SUZ^SUZ domain^150-201^E:7e-12,NA,NA,NA,,
yes,AD,CAMP,DN28225_c1_g1_i1,DN28225_c1_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,.,NA,NA,NA,NA,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i5,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i10,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^164-231^E:7.7e-24,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i7,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i1,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^93-160^E:3.6e-24,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i4,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN20116_c0_g1_i6,DN20116_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^161-228^E:7.5e-24,NA,NA,NA,NA,,
yes,AD,CAMP,DN60152_c0_g1_i1,DN60152_c0_g1,PDE4B_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",.,NA,NA,NA,NA,KEGG:rno:24626`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN51099_c0_g1_i3,DN51099_c0_g1,PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^171-218^E:0.00014,PF00989.25^PAS^PAS fold^173-267^E:6.9e-09,PF08448.10^PAS_4^PAS fold^173-261^E:6.6e-06,PF13426.7^PAS_9^PAS domain^178-266^E:8.6e-11,NA,,
yes,AD,CAMP,DN51099_c0_g1_i1,DN51099_c0_g1,PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^171-218^E:0.00017,PF00989.25^PAS^PAS fold^173-273^E:3.8e-11,PF08448.10^PAS_4^PAS fold^173-269^E:2.2e-06,PF13426.7^PAS_9^PAS domain^178-274^E:9.9e-13,PF08447.12^PAS_3^PAS fold^191-273^E:7.3e-06,,
yes,AD,CAMP,DN51099_c0_g1_i2,DN51099_c0_g1,PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i7,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,.,NA,NA,NA,NA,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i10,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^9-176^E:5.8e-46,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i3,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^172-405^E:9.8e-76,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i6,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i8,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,.,NA,NA,NA,NA,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i9,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,.,NA,NA,NA,NA,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN3529_c0_g1_i1,DN3529_c0_g1,PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",PDE7B_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 7B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007268^biological_process^chemical synaptic transmission,KEGG:hsa:27115`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^172-240^E:6e-23,NA,NA,NA,NA,,
yes,AD,CAMP,DN2697_c2_g1_i2,DN2697_c2_g1,CRBL2_HUMAN,cAMP-responsive element-binding protein-like 2,CRBL2_HUMAN,cAMP-responsive element-binding protein-like 2,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",KEGG:hsa:1389,ENOG4111T4Y^cAMP responsive element binding protein-like 2,PF07716.15^bZIP_2^Basic region leucine zipper^27-75^E:2.8e-08,NA,NA,NA,NA,,
yes,AD,CAMP,DN2697_c2_g1_i1,DN2697_c2_g1,CRBL2_HUMAN,cAMP-responsive element-binding protein-like 2,CRBL2_HUMAN,cAMP-responsive element-binding protein-like 2,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",KEGG:hsa:1389,ENOG4111T4Y^cAMP responsive element binding protein-like 2,PF07716.15^bZIP_2^Basic region leucine zipper^27-75^E:3.2e-08,NA,NA,NA,NA,,
yes,AD,CAMP,DN48586_c0_g1_i1,DN48586_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN48586_c1_g1_i1,DN48586_c1_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN6651_c0_g1_i1,DN6651_c0_g1,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN6651_c0_g1_i3,DN6651_c0_g1,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN6651_c0_g1_i5,DN6651_c0_g1,IPKB_HUMAN,cAMP-dependent protein kinase inhibitor beta,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004862^molecular_function^cAMP-dependent protein kinase inhibitor activity,GO:2000480^biological_process^negative regulation of cAMP-dependent protein kinase activity,GO:0051973^biological_process^positive regulation of telomerase activity,.,NA,NA,NA,NA,KEGG:hsa:5570,ENOG410Y067^cAMP-dependent protein kinase inhibitor activity,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i3,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",.,NA,NA,NA,NA,KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i5,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF01590.26^GAF^GAF domain^5-90^E:3.2e-14,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^192-421^E:1.8e-70,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i11,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF01590.26^GAF^GAF domain^81-212^E:8.9e-08,PF13185.6^GAF_2^GAF domain^120-221^E:3.9e-07,PF01590.26^GAF^GAF domain^254-399^E:1.6e-18,PF13185.6^GAF_2^GAF domain^254-400^E:8.2e-09,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^501-731^E:1.9e-70,,
yes,AD,CAMP,DN22411_c0_g1_i6,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF13185.6^GAF_2^GAF domain^4-91^E:6.5e-07,PF01590.26^GAF^GAF domain^5-90^E:8.9e-15,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i12,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF01590.26^GAF^GAF domain^358-488^E:1.4e-07,PF13185.6^GAF_2^GAF domain^397-498^E:6e-07,PF01590.26^GAF^GAF domain^531-676^E:2.5e-18,PF13185.6^GAF_2^GAF domain^531-677^E:1.3e-08,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^778-1008^E:3.3e-70,,
yes,AD,CAMP,DN22411_c0_g1_i7,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^1-86^E:1.2e-20,NA,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i4,DN22411_c0_g1,PDE10_HUMAN,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_HUMAN,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity","GO:0004114^molecular_function^3',5'-cyclic-nucleotide phosphodiesterase activity",GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity","GO:0004114^molecular_function^3',5'-cyclic-nucleotide phosphodiesterase activity",KEGG:hsa:10846`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF01590.26^GAF^GAF domain^5-90^E:2.8e-14,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^192-422^E:5e-71,NA,NA,NA,,
yes,AD,CAMP,DN22411_c0_g1_i1,DN22411_c0_g1,PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",PDE10_RAT,"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0043025^cellular_component^neuronal cell body,GO:0043204^cellular_component^perikaryon,"GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",KEGG:rno:63885`KO:K18438,ENOG410XRI7^Phosphodiesterase,PF01590.26^GAF^GAF domain^358-489^E:6.5e-08,PF13185.6^GAF_2^GAF domain^397-498^E:2.9e-07,NA,NA,NA,,
no,AD,CAMP,DN5779_c0_g1_i9,DN5779_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN5779_c0_g1_i1,DN5779_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN5779_c0_g1_i4,DN5779_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^104-448^E:3.9e-33,PF12832.7^MFS_1_like^MFS_1 like family^137-457^E:3.1e-08,NA,NA,NA,,
no,AD,CAMP,DN5779_c0_g1_i2,DN5779_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^3-262^E:2.8e-26,PF12832.7^MFS_1_like^MFS_1 like family^30-271^E:6.4e-09,NA,NA,NA,,
no,AD,CAMP,DN5779_c0_g2_i1,DN5779_c0_g2,MF14C_HUMAN,Hippocampus abundant transcript-like protein 2 {ECO:0000312|HGNC:HGNC:23672},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i2,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^1-83^E:6.2e-28,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i5,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i6,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^84-310^E:1.3e-77,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i8,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i3,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i9,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^5-137^E:1e-37,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i7,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN173_c1_g1_i4,DN173_c1_g1,PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",PDE7A_HUMAN,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:5150`KO:K18436,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^116-342^E:1.7e-77,NA,NA,NA,NA,,
yes,AD,CAMP,DN531_c0_g2_i2,DN531_c0_g2,PRKX_HUMAN,cAMP-dependent protein kinase catalytic subunit PRKX,PRKX_HUMAN,cAMP-dependent protein kinase catalytic subunit PRKX,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5613`KO:K19584,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^57-293^E:1.4e-34,PF00069.25^Pkinase^Protein kinase domain^58-310^E:1.8e-68,PF14531.6^Kinase-like^Kinase-like^162-293^E:3.5e-07,NA,NA,,
yes,AD,CAMP,DN531_c0_g2_i3,DN531_c0_g2,PRKX_HUMAN,cAMP-dependent protein kinase catalytic subunit PRKX,PRKX_HUMAN,cAMP-dependent protein kinase catalytic subunit PRKX,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5613`KO:K19584,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^57-293^E:1.4e-34,PF00069.25^Pkinase^Protein kinase domain^58-310^E:1.8e-68,PF14531.6^Kinase-like^Kinase-like^162-293^E:3.5e-07,NA,NA,,
yes,AD,CAMP,DN531_c0_g2_i1,DN531_c0_g2,PRKX_HUMAN,cAMP-dependent protein kinase catalytic subunit PRKX,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:5613`KO:K19584,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN521_c1_g1_i7,DN521_c1_g1,CR3L2_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 2,CR3L2_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:64764`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,PF08312.12^cwf21^cwf21 domain^104-147^E:2.6e-13,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^532-603^E:5.1e-06,PF00170.21^bZIP_1^bZIP transcription factor^537-599^E:1e-13,PF07716.15^bZIP_2^Basic region leucine zipper^541-590^E:1.1e-08,NA,,
yes,AD,CAMP,DN2175_c3_g1_i1,DN2175_c3_g1,KAP3_HUMAN,cAMP-dependent protein kinase type II-beta regulatory subunit,KAP3_HUMAN,cAMP-dependent protein kinase type II-beta regulatory subunit,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:hsa:5577`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^30-66^E:1.3e-14,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^202-285^E:2.8e-14,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^322-412^E:1.2e-19,NA,NA,,
yes,AD,CAMP,DN2175_c3_g1_i2,DN2175_c3_g1,KAP3_HUMAN,cAMP-dependent protein kinase type II-beta regulatory subunit,KAP3_HUMAN,cAMP-dependent protein kinase type II-beta regulatory subunit,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:hsa:5577`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^30-66^E:1.3e-14,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^219-302^E:2.9e-14,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^339-429^E:1.3e-19,NA,NA,,
no,AD,CAMP,DN52603_c0_g1_i1,DN52603_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN34573_c0_g1_i1,DN34573_c0_g1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,.,NA,NA,NA,NA,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN34573_c2_g1_i1,DN34573_c2_g1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,.,NA,NA,NA,NA,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN34573_c3_g1_i1,DN34573_c3_g1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,.,NA,NA,NA,NA,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
no,AD,CAMP,DN50942_c0_g1_i1,DN50942_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i13,DN15643_c0_g1,KAPCA_PIG,cAMP-dependent protein kinase catalytic subunit alpha,KAPCA_HUMAN,cAMP-dependent protein kinase catalytic subunit alpha,GO:0001669^cellular_component^acrosomal vesicle,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0042585^cellular_component^germinal vesicle,GO:0001669^cellular_component^acrosomal vesicle,GO:0034704^cellular_component^calcium channel complex,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,KEGG:hsa:5566`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^1-180^E:1.3e-51,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^1-163^E:1.6e-23,PF14531.6^Kinase-like^Kinase-like^24-163^E:8.5e-09,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i1,DN15643_c0_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^90-344^E:3.3e-73,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-327^E:1.1e-34,PF14531.6^Kinase-like^Kinase-like^187-327^E:2e-08,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i14,DN15643_c0_g1,KAPCA_SHEEP,cAMP-dependent protein kinase catalytic subunit alpha,.,NA,GO:0001669^cellular_component^acrosomal vesicle,GO:0005737^cellular_component^cytoplasm,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,.,NA,NA,NA,NA,KEGG:oas:443094`KO:K04345,.,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i4,DN15643_c0_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^121-375^E:4.1e-73,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^123-358^E:1.3e-34,PF14531.6^Kinase-like^Kinase-like^218-358^E:2.3e-08,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i5,DN15643_c0_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^90-228^E:4.2e-40,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-229^E:1.6e-18,NA,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i10,DN15643_c0_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^90-228^E:4.2e-40,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-229^E:1.6e-18,NA,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i3,DN15643_c0_g1,KAPCA_HUMAN,cAMP-dependent protein kinase catalytic subunit alpha,KAPCA_HUMAN,cAMP-dependent protein kinase catalytic subunit alpha,GO:0001669^cellular_component^acrosomal vesicle,GO:0034704^cellular_component^calcium channel complex,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0001669^cellular_component^acrosomal vesicle,GO:0034704^cellular_component^calcium channel complex,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,KEGG:hsa:5566`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^32-137^E:5.4e-10,PF00069.25^Pkinase^Protein kinase domain^38-154^E:2.6e-26,NA,NA,NA,,
yes,AD,CAMP,DN15643_c0_g1_i2,DN15643_c0_g1,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,KAPCB_HUMAN,cAMP-dependent protein kinase catalytic subunit beta,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:5567`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00069.25^Pkinase^Protein kinase domain^90-344^E:3.3e-73,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-327^E:1.1e-34,PF14531.6^Kinase-like^Kinase-like^187-327^E:2e-08,NA,NA,,
no,AD,CAMP,DN15614_c0_g1_i1,DN15614_c0_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF08683.11^CAMSAP_CKK^Microtubule-binding calmodulin-regulated spectrin-associated^96-214^E:8e-49,NA,NA,NA,NA,,
no,AD,CAMP,DN14821_c0_g1_i2,DN14821_c0_g1,ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:380660`KO:K01908,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^60-114^E:6.2e-17,PF00501.28^AMP-binding^AMP-binding enzyme^121-559^E:2.8e-81,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^569-647^E:1.6e-18,NA,NA,,
no,AD,CAMP,DN14821_c0_g1_i4,DN14821_c0_g1,ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:380660`KO:K01908,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^60-114^E:1.3e-17,PF00501.28^AMP-binding^AMP-binding enzyme^121-215^E:6.7e-21,NA,NA,NA,,
no,AD,CAMP,DN14821_c0_g1_i5,DN14821_c0_g1,ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",ACSS3_MOUSE,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:380660`KO:K01908,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF16177.5^ACAS_N^Acetyl-coenzyme A synthetase N-terminus^60-114^E:4.9e-17,PF00501.28^AMP-binding^AMP-binding enzyme^121-559^E:1.6e-81,NA,NA,NA,,
no,AD,CAMP,DN46588_c0_g1_i1,DN46588_c0_g1,R3HD2_BOVIN,R3H domain-containing protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:613499,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
no,AD,CAMP,DN46514_c0_g1_i1,DN46514_c0_g1,R3HD2_BOVIN,R3H domain-containing protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:613499,"ENOG4111U9N^cAMP-regulated phosphoprotein, 21kDa",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN54854_c0_g1_i1,DN54854_c0_g1,PDE4A_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:18577`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN19572_c0_g1_i2,DN19572_c0_g1,KAP2_BOVIN,cAMP-dependent protein kinase type II-alpha regulatory subunit,KAP2_BOVIN,cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031588^cellular_component^nucleotide-activated protein kinase complex,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031588^cellular_component^nucleotide-activated protein kinase complex,KEGG:bta:100139910`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^82-118^E:7.9e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^229-314^E:1.1e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^351-441^E:1.6e-21,NA,NA,,
yes,AD,CAMP,DN19572_c0_g1_i1,DN19572_c0_g1,KAP2_BOVIN,cAMP-dependent protein kinase type II-alpha regulatory subunit,KAP2_BOVIN,cAMP-dependent protein kinase type II-alpha regulatory subunit,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031588^cellular_component^nucleotide-activated protein kinase complex,GO:0005930^cellular_component^axoneme,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031588^cellular_component^nucleotide-activated protein kinase complex,KEGG:bta:100139910`KO:K04739,"COG0664^transcriptional regulator, crp fnr family",PF02197.17^RIIa^Regulatory subunit of type II PKA R-subunit^80-116^E:7.8e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^227-312^E:1.1e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^349-439^E:1.6e-21,NA,NA,,
no,AD,CAMP,DN5502_c2_g1_i1,DN5502_c2_g1,MF14C_HUMAN,Hippocampus abundant transcript-like protein 2 {ECO:0000312|HGNC:HGNC:23672},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN5502_c2_g1_i3,DN5502_c2_g1,MF14B_HUMAN,Hippocampus abundant transcript-like protein 1 {ECO:0000312|HGNC:HGNC:23376},MF14B_HUMAN,Hippocampus abundant transcript-like protein 1 {ECO:0000312|HGNC:HGNC:23376},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,KEGG:hsa:84641,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^61-405^E:1.9e-33,PF12832.7^MFS_1_like^MFS_1 like family^94-412^E:6.5e-11,NA,NA,NA,,
no,AD,CAMP,DN27795_c0_g1_i2,DN27795_c0_g1,MF14C_HUMAN,Hippocampus abundant transcript-like protein 2 {ECO:0000312|HGNC:HGNC:23672},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN27795_c0_g1_i4,DN27795_c0_g1,MF14C_HUMAN,Hippocampus abundant transcript-like protein 2 {ECO:0000312|HGNC:HGNC:23672},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN27795_c0_g1_i1,DN27795_c0_g1,MF14C_HUMAN,Hippocampus abundant transcript-like protein 2 {ECO:0000312|HGNC:HGNC:23672},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0022857^molecular_function^transmembrane transporter activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1866_c1_g1_i8,DN1866_c1_g1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,KEGG:bta:281713`KO:K05870,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^99-139^E:3e-21,PF00170.21^bZIP_1^bZIP transcription factor^267-322^E:9.8e-19,PF07716.15^bZIP_2^Basic region leucine zipper^273-319^E:3.6e-07,PF18515.1^Rh5^Rh5 coiled-coil domain^287-326^E:0.071,NA,,
yes,AD,CAMP,DN1866_c1_g1_i3,DN1866_c1_g1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,KEGG:bta:281713`KO:K05870,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^59-99^E:2.5e-21,PF00170.21^bZIP_1^bZIP transcription factor^227-282^E:8e-19,PF07716.15^bZIP_2^Basic region leucine zipper^233-279^E:3e-07,PF18515.1^Rh5^Rh5 coiled-coil domain^247-286^E:0.049,NA,,
yes,AD,CAMP,DN1866_c1_g1_i1,DN1866_c1_g1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,.,NA,NA,NA,NA,KEGG:bta:281713`KO:K05870,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1866_c1_g1_i5,DN1866_c1_g1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,CREB1_BOVIN,Cyclic AMP-responsive element-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0030154^biological_process^cell differentiation,KEGG:bta:281713`KO:K05870,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^99-139^E:3e-21,PF00170.21^bZIP_1^bZIP transcription factor^267-322^E:9.8e-19,PF07716.15^bZIP_2^Basic region leucine zipper^273-319^E:3.6e-07,PF18515.1^Rh5^Rh5 coiled-coil domain^287-326^E:0.071,NA,,
yes,AD,CAMP,DN1889_c0_g2_i9,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^179-222^E:0.047,PF00989.25^PAS^PAS fold^181-282^E:1e-11,PF08448.10^PAS_4^PAS fold^182-284^E:6e-05,PF13426.7^PAS_9^PAS domain^187-285^E:1.2e-11,PF08447.12^PAS_3^PAS fold^200-282^E:9.5e-06,,
yes,AD,CAMP,DN1889_c0_g2_i2,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^179-222^E:0.029,PF00989.25^PAS^PAS fold^181-282^E:5.8e-12,PF08448.10^PAS_4^PAS fold^182-284^E:3.4e-05,PF13426.7^PAS_9^PAS domain^187-285^E:6.8e-12,PF08447.12^PAS_3^PAS fold^200-282^E:5.6e-06,,
yes,AD,CAMP,DN1889_c0_g2_i5,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^158-201^E:0.016,PF00989.25^PAS^PAS fold^160-255^E:1.1e-10,PF13426.7^PAS_9^PAS domain^166-255^E:2.4e-10,PF08447.12^PAS_3^PAS fold^179-240^E:1.1e-05,NA,,
yes,AD,CAMP,DN1889_c0_g2_i6,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF08629.10^PDE8^PDE8 phosphodiesterase^44-94^E:1.4e-25,PF13188.7^PAS_8^PAS domain^287-330^E:0.056,PF00989.25^PAS^PAS fold^289-390^E:1.2e-11,PF08448.10^PAS_4^PAS fold^290-392^E:7.1e-05,PF13426.7^PAS_9^PAS domain^295-393^E:1.4e-11,,
yes,AD,CAMP,DN1889_c0_g2_i10,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,.,NA,NA,NA,NA,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1889_c0_g2_i7,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF13188.7^PAS_8^PAS domain^158-201^E:0.019,PF00989.25^PAS^PAS fold^160-261^E:3.5e-12,PF08448.10^PAS_4^PAS fold^161-263^E:2.1e-05,PF13426.7^PAS_9^PAS domain^166-264^E:4.3e-12,PF08447.12^PAS_3^PAS fold^179-261^E:3.6e-06,,
yes,AD,CAMP,DN1889_c0_g2_i1,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF08629.10^PDE8^PDE8 phosphodiesterase^44-94^E:4.5e-26,PF13188.7^PAS_8^PAS domain^287-330^E:0.018,PF00989.25^PAS^PAS fold^289-383^E:3.6e-10,PF13426.7^PAS_9^PAS domain^295-381^E:1.2e-09,NA,,
yes,AD,CAMP,DN1889_c0_g2_i8,DN1889_c0_g2,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^175-426^E:9.7e-97,NA,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i1,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i8,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^203-283^E:9.3e-16,NA,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i5,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^203-283^E:2e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^321-407^E:1.7e-20,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i10,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^233-313^E:2.2e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^351-437^E:1.8e-20,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i15,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^203-283^E:1.6e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^321-401^E:2.9e-18,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i14,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^23-110^E:2.2e-21,NA,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i2,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^203-283^E:2e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^321-407^E:1.7e-20,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i11,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^203-283^E:2e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^321-407^E:1.7e-20,NA,NA,NA,,
no,AD,CAMP,DN16097_c0_g1_i9,DN16097_c0_g1,KGP2_HUMAN,cGMP-dependent protein kinase 2,KGP2_HUMAN,cGMP-dependent protein kinase 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,GO:0016324^cellular_component^apical plasma membrane,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:5593`KO:K19477,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^233-313^E:1.7e-15,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^351-431^E:3.3e-18,NA,NA,NA,,
no,AD,CAMP,DN66925_c0_g1_i1,DN66925_c0_g1,ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:68738`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN66925_c1_g1_i1,DN66925_c1_g1,ACS2L_MOUSE,"Acetyl-coenzyme A synthetase 2-like, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:68738`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN386_c2_g2_i3,DN386_c2_g2,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^112-167^E:0.00023,PF00170.21^bZIP_1^bZIP transcription factor^117-171^E:1.7e-21,PF07716.15^bZIP_2^Basic region leucine zipper^121-168^E:4.3e-09,PF18515.1^Rh5^Rh5 coiled-coil domain^135-174^E:0.016,NA,,
yes,AD,CAMP,DN386_c2_g2_i5,DN386_c2_g2,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^146-186^E:3.8e-18,PF00170.21^bZIP_1^bZIP transcription factor^313-367^E:6e-21,PF07716.15^bZIP_2^Basic region leucine zipper^317-364^E:1.5e-08,PF18515.1^Rh5^Rh5 coiled-coil domain^332-370^E:0.058,NA,,
yes,AD,CAMP,DN386_c2_g2_i1,DN386_c2_g2,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^55-95^E:2.5e-18,PF00170.21^bZIP_1^bZIP transcription factor^222-276^E:3.9e-21,PF07716.15^bZIP_2^Basic region leucine zipper^226-273^E:9.7e-09,PF18515.1^Rh5^Rh5 coiled-coil domain^240-279^E:0.036,NA,,
no,AD,CAMP,DN32495_c5_g1_i1,DN32495_c5_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN40742_c0_g1_i1,DN40742_c0_g1,PDE7A_MOUSE,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,.,NA,NA,NA,NA,KEGG:mmu:18583`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i3,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^35-253^E:3.2e-19,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i10,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^35-253^E:3.2e-19,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i12,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^35-138^E:1e-09,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i1,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^151-240^E:2.2e-05,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i5,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^157-246^E:2.3e-05,NA,NA,NA,NA,,
no,AD,CAMP,DN4947_c0_g1_i11,DN4947_c0_g1,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,PPA5_MOUSE,Tartrate-resistant acid phosphatase type 5,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,GO:0005764^cellular_component^lysosome,GO:0003993^molecular_function^acid phosphatase activity,GO:0008199^molecular_function^ferric iron binding,GO:0008198^molecular_function^ferrous iron binding,GO:0060349^biological_process^bone morphogenesis,KEGG:mmu:11433`KO:K14379,"COG1409^Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)",PF00149.28^Metallophos^Calcineurin-like phosphoesterase^35-253^E:3.2e-19,NA,NA,NA,NA,,
no,AD,CAMP,DN8905_c2_g1_i1,DN8905_c2_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^146-223^E:8.3e-29,NA,NA,NA,NA,,
no,AD,CAMP,DN8905_c2_g1_i5,DN8905_c2_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,.,NA,NA,NA,NA,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN8905_c2_g1_i6,DN8905_c2_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^130-207^E:7.6e-29,NA,NA,NA,NA,,
no,AD,CAMP,DN8905_c2_g1_i3,DN8905_c2_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_HUMAN,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005516^molecular_function^calmodulin binding,KEGG:hsa:57662`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^11-88^E:2.2e-28,PF17095.5^CAMSAP_CC1^Spectrin-binding region of Ca2+-Calmodulin^389-436^E:4.9e-22,NA,NA,NA,,
no,AD,CAMP,DN8905_c2_g1_i4,DN8905_c2_g1,CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},CAMP3_MOUSE,Calmodulin-regulated spectrin-associated protein 3 {ECO:0000305},GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0036449^cellular_component^microtubule minus-end,GO:0005915^cellular_component^zonula adherens,GO:0051015^molecular_function^actin filament binding,KEGG:mmu:69697`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,PF11971.8^CAMSAP_CH^CAMSAP CH domain^157-234^E:8.8e-29,NA,NA,NA,NA,,
no,AD,CAMP,DN8930_c0_g1_i3,DN8930_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^5-268^E:1.4e-25,PF12832.7^MFS_1_like^MFS_1 like family^6-277^E:8.8e-09,NA,NA,NA,,
no,AD,CAMP,DN8930_c0_g1_i1,DN8930_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^4-267^E:4.5e-25,PF12832.7^MFS_1_like^MFS_1 like family^5-276^E:1.7e-08,NA,NA,NA,,
no,AD,CAMP,DN8930_c0_g1_i8,DN8930_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN8930_c0_g1_i6,DN8930_c0_g1,MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,.,NA,NA,NA,NA,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
no,AD,CAMP,DN8930_c0_g1_i4,DN8930_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},MF14A_MOUSE,Hippocampus abundant transcript 1 protein {ECO:0000250|UniProtKB:Q96MC6},GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007286^biological_process^spermatid development,KEGG:mmu:15247,ENOG410ZVCA^solute carrier family 46,PF07690.16^MFS_1^Major Facilitator Superfamily^4-267^E:2.3e-25,PF12832.7^MFS_1_like^MFS_1 like family^5-276^E:9e-09,NA,NA,NA,,
no,AD,CAMP,DN8930_c2_g1_i1,DN8930_c2_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i13,DN1348_c0_g2,CREM_MOUSE,cAMP-responsive element modulator,CREM_BOVIN,cAMP-responsive element modulator,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,NA,KEGG:bta:540605`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF00170.21^bZIP_1^bZIP transcription factor^77-134^E:3e-21,PF03131.17^bZIP_Maf^bZIP Maf transcription factor^81-128^E:0.00032,PF07716.15^bZIP_2^Basic region leucine zipper^83-129^E:7.7e-08,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i14,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_BOVIN,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,NA,KEGG:bta:540605`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^115-153^E:3.5e-19,NA,NA,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i18,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^51-89^E:1.8e-19,NA,NA,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i12,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF00170.21^bZIP_1^bZIP transcription factor^83-138^E:1.4e-19,PF07716.15^bZIP_2^Basic region leucine zipper^89-135^E:9.2e-08,PF18515.1^Rh5^Rh5 coiled-coil domain^103-140^E:0.02,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i16,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^115-153^E:7.5e-19,PF00170.21^bZIP_1^bZIP transcription factor^285-340^E:7e-19,PF07716.15^bZIP_2^Basic region leucine zipper^291-337^E:4.6e-07,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i11,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^100-138^E:3.1e-19,NA,NA,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i5,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF00170.21^bZIP_1^bZIP transcription factor^58-100^E:1e-15,PF07716.15^bZIP_2^Basic region leucine zipper^58-97^E:2e-07,PF18515.1^Rh5^Rh5 coiled-coil domain^65-102^E:0.015,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i1,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_BOVIN,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,NA,KEGG:bta:540605`KO:K09052,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i2,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^66-104^E:6.1e-19,PF00170.21^bZIP_1^bZIP transcription factor^236-291^E:5.5e-19,PF07716.15^bZIP_2^Basic region leucine zipper^242-288^E:3.6e-07,PF18515.1^Rh5^Rh5 coiled-coil domain^256-293^E:0.083,NA,,
yes,AD,CAMP,DN1348_c0_g2_i22,DN1348_c0_g2,CREM_BOVIN,cAMP-responsive element modulator,CREM_BOVIN,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,NA,KEGG:bta:540605`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF02173.17^pKID^pKID domain^51-89^E:5.6e-19,PF00170.21^bZIP_1^bZIP transcription factor^221-278^E:1.2e-20,PF07716.15^bZIP_2^Basic region leucine zipper^227-273^E:3e-07,NA,NA,,
yes,AD,CAMP,DN1348_c0_g2_i9,DN1348_c0_g2,CREM_CANLF,cAMP-responsive element modulator,CREM_CANLF,cAMP-responsive element modulator,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0006687^biological_process^glycosphingolipid metabolic process,KEGG:cfa:403887`KO:K09052,ENOG410ZZJZ^cAMP responsive element,PF00170.21^bZIP_1^bZIP transcription factor^77-132^E:1.3e-19,PF07716.15^bZIP_2^Basic region leucine zipper^83-129^E:8.4e-08,PF18515.1^Rh5^Rh5 coiled-coil domain^97-134^E:0.018,NA,NA,,
yes,AD,CAMP,DN20021_c3_g1_i1,DN20021_c3_g1,KAP0_MESAU,cAMP-dependent protein kinase type I-alpha regulatory subunit {ECO:0000250|UniProtKB:P10644},.,NA,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN86143_c0_g1_i1,DN86143_c0_g1,PDE4A_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0098685^cellular_component^Schaffer collateral - CA1 synapse,.,NA,NA,NA,NA,KEGG:rno:25638`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i1,DN35551_c0_g2,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^71-420^E:1.5e-65,NA,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i4,DN35551_c0_g2,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^71-474^E:3.9e-82,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^484-564^E:1.2e-22,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i3,DN35551_c0_g2,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^71-474^E:3.9e-82,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^484-564^E:1.2e-22,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i13,DN35551_c0_g2,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^71-474^E:3.9e-82,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^484-564^E:1.2e-22,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i7,DN35551_c0_g2,ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^71-474^E:3.9e-82,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^484-564^E:1.2e-22,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i6,DN35551_c0_g2,ACSM3_PONAB,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_PONAB,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0046872^molecular_function^metal ion binding,KEGG:pon:100171624`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^10-227^E:3e-47,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^237-317^E:4.9e-23,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i11,DN35551_c0_g2,ACSM3_PONAB,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",ACSM3_PONAB,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0046872^molecular_function^metal ion binding,KEGG:pon:100171624`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^2-252^E:3.8e-56,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^262-342^E:5.6e-23,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g2_i2,DN35551_c0_g2,ACSM4_HUMAN,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",ACSM3_MOUSE,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0102391^molecular_function^decanoate-CoA ligase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,KEGG:mmu:20216`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^28-108^E:4.9e-24,NA,NA,NA,NA,,
no,AD,CAMP,DN35551_c0_g3_i1,DN35551_c0_g3,ACSM4_HUMAN,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0102391^molecular_function^decanoate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:hsa:341392`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN68127_c0_g1_i1,DN68127_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN66430_c0_g2_i1,DN66430_c0_g2,PDE4C_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4C",.,NA,GO:0005929^cellular_component^cilium,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0061179^biological_process^negative regulation of insulin secretion involved in cellular response to glucose stimulus,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN9344_c0_g2_i2,DN9344_c0_g2,CR3L1_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:90993`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN9344_c0_g2_i9,DN9344_c0_g2,CR3L1_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:90993`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN128368_c0_g1_i1,DN128368_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN196477_c0_g1_i1,DN196477_c0_g1,KAPCA_RAT,cAMP-dependent protein kinase catalytic subunit alpha,.,NA,GO:0001669^cellular_component^acrosomal vesicle,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,.,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN100944_c0_g1_i1,DN100944_c0_g1,ATF1_BOVIN,Cyclic AMP-dependent transcription factor ATF-1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0043565^molecular_function^sequence-specific DNA binding,.,NA,NA,NA,NA,KEGG:bta:506967`KO:K09053,ENOG410ZZJZ^cAMP responsive element,.,NA,NA,NA,NA,,
no,AD,CAMP,DN110288_c2_g1_i1,DN110288_c2_g1,ACSM3_RAT,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,.,NA,NA,NA,NA,KEGG:rno:24763`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN119232_c0_g1_i3,DN119232_c0_g1,PDE4C_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4C",.,NA,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:hsa:5143`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN119232_c0_g1_i1,DN119232_c0_g1,PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",PDE4D_MOUSE,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0031965^cellular_component^nuclear membrane,KEGG:mmu:238871`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF18100.1^PDE4_UCR^Phosphodiesterase 4 upstream conserved regions (UCR)^37-153^E:6.7e-52,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^277-355^E:4.5e-31,NA,NA,NA,,
yes,AD,CAMP,DN119232_c0_g1_i2,DN119232_c0_g1,PDE4C_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4C",PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^38-116^E:3.7e-32,NA,NA,NA,NA,,
yes,AD,CAMP,DN121878_c0_g1_i1,DN121878_c0_g1,PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN191349_c0_g1_i1,DN191349_c0_g1,PDE7A_MOUSE,"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0004112^molecular_function^cyclic-nucleotide phosphodiesterase activity,GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007165^biological_process^signal transduction,.,NA,NA,NA,NA,KEGG:mmu:18583`KO:K18436,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN148279_c0_g1_i1,DN148279_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN178521_c0_g1_i2,DN178521_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
no,AD,CAMP,DN178521_c0_g1_i1,DN178521_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN104135_c0_g1_i3,DN104135_c0_g1,PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B","GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^1-87^E:1.3e-30,NA,NA,NA,NA,,
yes,AD,CAMP,DN104135_c0_g1_i4,DN104135_c0_g1,PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^163-299^E:1.7e-54,NA,NA,NA,NA,,
yes,AD,CAMP,DN104135_c0_g1_i1,DN104135_c0_g1,PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B","GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,GO:0005829^cellular_component^cytosol,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0006198^biological_process^cAMP catabolic process,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:hsa:8622`KO:K18437,ENOG410XP9B^Phosphodiesterase,PF00233.19^PDEase_I^3'5'-cyclic nucleotide phosphodiesterase^163-415^E:2e-91,NA,NA,NA,NA,,
yes,AD,CAMP,DN104135_c0_g1_i2,DN104135_c0_g1,PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,.,NA,NA,NA,NA,.,ENOG410XP9B^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN129718_c0_g1_i1,DN129718_c0_g1,PDE4A_CAVPO,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0016787^molecular_function^hydrolase activity,GO:0006198^biological_process^cAMP catabolic process,NA,NA,.,NA,NA,NA,NA,.,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN186164_c0_g1_i1,DN186164_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN140051_c0_g1_i1,DN140051_c0_g1,KAPC1_CAEEL,cAMP-dependent protein kinase catalytic subunit,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,.,NA,NA,NA,NA,.,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN110014_c0_g1_i3,DN110014_c0_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,.,NA,NA,NA,NA,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN110014_c0_g1_i4,DN110014_c0_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,.,NA,NA,NA,NA,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN110014_c1_g1_i1,DN110014_c1_g1,KGP1_DROME,"cGMP-dependent protein kinase, isozyme 1",.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004691^molecular_function^cAMP-dependent protein kinase activity,.,NA,NA,NA,NA,KEGG:dme:Dmel_CG3324`KO:K07376,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
no,AD,CAMP,DN176379_c0_g1_i1,DN176379_c0_g1,ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN169578_c0_g1_i1,DN169578_c0_g1,PDE4A_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4A",.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:5141`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN107135_c0_g1_i1,DN107135_c0_g1,CAMP1_HUMAN,Calmodulin-regulated spectrin-associated protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005516^molecular_function^calmodulin binding,GO:0008017^molecular_function^microtubule binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:157922`KO:K17493,ENOG4111D0B^calmodulin regulated spectrin-associated protein,.,NA,NA,NA,NA,,
no,AD,CAMP,DN278003_c0_g1_i1,DN278003_c0_g1,CAMP2_MOUSE,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0036449^cellular_component^microtubule minus-end,GO:0005516^molecular_function^calmodulin binding,.,NA,NA,NA,NA,KEGG:mmu:67886`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN262337_c0_g1_i1,DN262337_c0_g1,PDE4B_RAT,"cAMP-specific 3',5'-cyclic phosphodiesterase 4B",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",.,NA,NA,NA,NA,KEGG:rno:24626`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN281207_c0_g1_i1,DN281207_c0_g1,PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B","GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,.,ENOG410XP9B^Phosphodiesterase,PF08629.10^PDE8^PDE8 phosphodiesterase^31-81^E:8.7e-27,NA,NA,NA,NA,,
yes,AD,CAMP,DN248950_c0_g1_i1,DN248950_c0_g1,PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN217883_c0_g1_i1,DN217883_c0_g1,ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN226181_c0_g1_i1,DN226181_c0_g1,ACSA_MOUSE,"Acetyl-coenzyme A synthetase, cytoplasmic",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0003987^molecular_function^acetate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:60525`KO:K01895,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN301738_c0_g1_i1,DN301738_c0_g1,CAMP2_HUMAN,Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:1990752^cellular_component^microtubule end,GO:0005516^molecular_function^calmodulin binding,GO:0051011^molecular_function^microtubule minus-end binding,.,NA,NA,NA,NA,KEGG:hsa:23271`KO:K17493,"ENOG411033G^calmodulin regulated spectrin-associated protein family, member 2",.,NA,NA,NA,NA,,
no,AD,CAMP,DN333721_c0_g1_i1,DN333721_c0_g1,AACS_CHICK,Acetoacetyl-CoA synthetase,.,NA,GO:0005829^cellular_component^cytosol,GO:0030729^molecular_function^acetoacetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:416811`KO:K01907,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN331828_c0_g1_i1,DN331828_c0_g1,KAPCB_RAT,cAMP-dependent protein kinase catalytic subunit beta,.,NA,GO:0005952^cellular_component^cAMP-dependent protein kinase complex,GO:0005813^cellular_component^centrosome,GO:0097546^cellular_component^ciliary base,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:rno:293508`KO:K04345,"ENOG410XPQQ^CAMP-dependent protein kinase, catalytic subunit",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN341224_c0_g1_i1,DN341224_c0_g1,PDE8A_HUMAN,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A",.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity","GO:0047555^molecular_function^3',5'-cyclic-GMP phosphodiesterase activity",GO:0019900^molecular_function^kinase binding,.,NA,NA,NA,NA,KEGG:hsa:5151`KO:K18437,ENOG410XP9B^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN309271_c0_g1_i1,DN309271_c0_g1,ACSM4_RAT,"Acyl-coenzyme A synthetase ACSM4, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:rno:353317`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CAMP,DN329247_c0_g1_i1,DN329247_c0_g1,CR3L1_HUMAN,Cyclic AMP-responsive element-binding protein 3-like protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:90993`KO:K09048,ENOG410ZZQM^cAMP responsive element binding protein,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN365008_c0_g1_i1,DN365008_c0_g1,PDE8B_MOUSE,"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B",.,NA,"GO:0004115^molecular_function^3',5'-cyclic-AMP phosphodiesterase activity",GO:0046872^molecular_function^metal ion binding,GO:0001662^biological_process^behavioral fear response,GO:0006198^biological_process^cAMP catabolic process,GO:0046676^biological_process^negative regulation of insulin secretion,.,NA,NA,NA,NA,.,ENOG410XP9B^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN466235_c0_g1_i1,DN466235_c0_g1,ACSS3_BOVIN,"Acyl-CoA synthetase short-chain family member 3, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0003987^molecular_function^acetate-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0050218^molecular_function^propionate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:bta:531552`KO:K01908,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN412903_c0_g1_i1,DN412903_c0_g1,MF14A_HUMAN,Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0022857^molecular_function^transmembrane transporter activity,GO:0001675^biological_process^acrosome assembly,GO:0030382^biological_process^sperm mitochondrion organization,GO:0007289^biological_process^spermatid nucleus differentiation,.,NA,NA,NA,NA,KEGG:hsa:64645,ENOG410ZVCA^solute carrier family 46,.,NA,NA,NA,NA,,
yes,AD,CAMP,DN451444_c0_g1_i1,DN451444_c0_g1,PDE4D_HUMAN,"cAMP-specific 3',5'-cyclic phosphodiesterase 4D",.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0034704^cellular_component^calcium channel complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5144`KO:K13293,ENOG410XRI7^Phosphodiesterase,.,NA,NA,NA,NA,,
no,AD,CAMP,DN469589_c0_g1_i1,DN469589_c0_g1,ACSM2_MOUSE,"Acyl-coenzyme A synthetase ACSM2, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003996^molecular_function^acyl-CoA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0018858^molecular_function^benzoate-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:233799`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
no,AD,CAMP,DN414580_c0_g1_i1,DN414580_c0_g1,ACSM3_PONAB,"Acyl-coenzyme A synthetase ACSM3, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0015645^molecular_function^fatty acid ligase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:pon:100171624`KO:K01896,"COG0365^Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)",.,NA,NA,NA,NA,,
yes,AD,CCL,DN6955_c0_g1_i1,DN6955_c0_g1,CCL28_HUMAN,C-C motif chemokine 28,.,NA,GO:0005623^cellular_component^cell,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,.,NA,NA,NA,NA,KEGG:hsa:56477`KO:K05513,ENOG411138S^chemokine (C-C motif) ligand 28,.,NA,NA,NA,NA,,
no,AD,CCL,DN57089_c0_g1_i1,DN57089_c0_g1,OCLN_CHICK,Occludin,.,NA,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,.,NA,NA,NA,NA,KEGG:gga:396026`KO:K06088,.,.,NA,NA,NA,NA,,
yes,AD,CCL,DN11217_c0_g1_i3,DN11217_c0_g1,CCL13_HUMAN,C-C motif chemokine 13,CCL13_HUMAN,C-C motif chemokine 13,GO:0005623^cellular_component^cell,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0005623^cellular_component^cell,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,KEGG:hsa:6357`KO:K16595,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^73-126^E:4.3e-14",NA,NA,NA,NA,,
no,AD,CCL,DN4575_c0_g1_i1,DN4575_c0_g1,EF1A3_MUCCL,Elongation factor 1-alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0003746^molecular_function^translation elongation factor activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,CCL,DN4575_c0_g1_i4,DN4575_c0_g1,EF1A3_MUCCL,Elongation factor 1-alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0003746^molecular_function^translation elongation factor activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,CCL,DN6793_c0_g1_i9,DN6793_c0_g1,OCLN_CHICK,Occludin,OCLN_CHICK,Occludin,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,KEGG:gga:396026`KO:K06088,.,PF01284.23^MARVEL^Membrane-associating domain^52-232^E:4.6e-25,NA,NA,NA,NA,,
no,AD,CCL,DN6793_c0_g1_i7,DN6793_c0_g1,OCLN_CHICK,Occludin,OCLN_CHICK,Occludin,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,KEGG:gga:396026`KO:K06088,.,.,NA,NA,NA,NA,,
no,AD,CCL,DN6793_c0_g1_i4,DN6793_c0_g1,OCLN_CHICK,Occludin,OCLN_CHICK,Occludin,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,KEGG:gga:396026`KO:K06088,.,PF01284.23^MARVEL^Membrane-associating domain^86-286^E:4.4e-30,PF07303.13^Occludin_ELL^Occludin homology domain^440-539^E:2.8e-28,NA,NA,NA,,
no,AD,CCL,DN6793_c0_g1_i10,DN6793_c0_g1,OCLN_CHICK,Occludin,OCLN_CHICK,Occludin,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,GO:0005923^cellular_component^bicellular tight junction,GO:0030054^cellular_component^cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0070830^biological_process^bicellular tight junction assembly,KEGG:gga:396026`KO:K06088,.,PF01284.23^MARVEL^Membrane-associating domain^52-252^E:3.8e-30,PF07303.13^Occludin_ELL^Occludin homology domain^406-505^E:2.5e-28,NA,NA,NA,,
yes,AD,CCL,DN13412_c0_g1_i3,DN13412_c0_g1,CCL13_HUMAN,C-C motif chemokine 13,.,NA,GO:0005623^cellular_component^cell,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,.,NA,NA,NA,NA,KEGG:hsa:6357`KO:K16595,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
no,AD,CCL,DN647_c0_g1_i9,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,CCL19_MOUSE,C-C motif chemokine 19,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031735^molecular_function^CCR10 chemokine receptor binding,GO:0031732^molecular_function^CCR7 chemokine receptor binding,KEGG:mmu:100039053`KEGG:mmu:24047`KO:K05512,ENOG410ZG6G^chemokine (C-C motif) ligand 19,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^64-121^E:1.3e-16",NA,NA,NA,NA,,
no,AD,CCL,DN647_c0_g1_i13,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,CCL19_MOUSE,C-C motif chemokine 19,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031735^molecular_function^CCR10 chemokine receptor binding,GO:0031732^molecular_function^CCR7 chemokine receptor binding,KEGG:mmu:100039053`KEGG:mmu:24047`KO:K05512,ENOG410ZG6G^chemokine (C-C motif) ligand 19,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^64-121^E:1.3e-16",NA,NA,NA,NA,,
yes,AD,CCL,DN9204_c0_g1_i7,DN9204_c0_g1,CCL26_CANLF,C-C motif chemokine 26,CCL26_CANLF,C-C motif chemokine 26,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031728^molecular_function^CCR3 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031728^molecular_function^CCR3 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,KEGG:cfa:448789`KO:K21096,ENOG41115YQ^chemokine (C-C motif) ligand 26,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^29-88^E:1.6e-18",NA,NA,NA,NA,,
yes,AD,CCL,DN9204_c0_g1_i10,DN9204_c0_g1,CCL26_CANLF,C-C motif chemokine 26,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031728^molecular_function^CCR3 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,.,NA,NA,NA,NA,KEGG:cfa:448789`KO:K21096,ENOG41115YQ^chemokine (C-C motif) ligand 26,.,NA,NA,NA,NA,,
yes,AD,CCL,DN9204_c0_g1_i6,DN9204_c0_g1,CCL26_CANLF,C-C motif chemokine 26,CCL26_CANLF,C-C motif chemokine 26,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031728^molecular_function^CCR3 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031728^molecular_function^CCR3 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,KEGG:cfa:448789`KO:K21096,ENOG41115YQ^chemokine (C-C motif) ligand 26,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^29-88^E:1.6e-18",NA,NA,NA,NA,,
yes,AD,CCL,DN9204_c0_g1_i1,DN9204_c0_g1,CCL19_MOUSE,C-C motif chemokine 19,CCL19_MOUSE,C-C motif chemokine 19,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031735^molecular_function^CCR10 chemokine receptor binding,GO:0031732^molecular_function^CCR7 chemokine receptor binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031735^molecular_function^CCR10 chemokine receptor binding,GO:0031732^molecular_function^CCR7 chemokine receptor binding,KEGG:mmu:100039053`KEGG:mmu:24047`KO:K05512,ENOG410ZG6G^chemokine (C-C motif) ligand 19,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^7-66^E:6.7e-16",NA,NA,NA,NA,,
no,AD,CCL,DN46801_c1_g1_i1,DN46801_c1_g1,CRLD2_HUMAN,Cysteine-rich secretory protein LCCL domain-containing 2,.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:1904813^cellular_component^ficolin-1-rich granule lumen,.,NA,NA,NA,NA,KEGG:hsa:83716,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
yes,AD,CCL,DN12298_c0_g1_i2,DN12298_c0_g1,CCL4_PIG,C-C motif chemokine 4,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0035690^biological_process^cellular response to drug,GO:0071346^biological_process^cellular response to interferon-gamma,.,NA,NA,NA,NA,KEGG:ssc:396668`KO:K12964,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
yes,AD,CCL,DN17675_c0_g1_i5,DN17675_c0_g1,CCL4_CHICK,C-C motif chemokine 4 homolog,CCL4_CHICK,C-C motif chemokine 4 homolog,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,KEGG:gga:395551`KO:K12964,.,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^57-113^E:6e-22",NA,NA,NA,NA,,
yes,AD,CCL,DN17675_c0_g1_i6,DN17675_c0_g1,CCL4_CHICK,C-C motif chemokine 4 homolog,CCL4_CHICK,C-C motif chemokine 4 homolog,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,KEGG:gga:395551`KO:K12964,.,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^111-167^E:1.4e-21",NA,NA,NA,NA,,
yes,AD,CCL,DN17675_c0_g1_i7,DN17675_c0_g1,CCL4_CHICK,C-C motif chemokine 4 homolog,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,.,NA,NA,NA,NA,KEGG:gga:395551`KO:K12964,.,.,NA,NA,NA,NA,,
yes,AD,CCL,DN17675_c0_g1_i8,DN17675_c0_g1,CCL4_CHICK,C-C motif chemokine 4 homolog,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,.,NA,NA,NA,NA,KEGG:gga:395551`KO:K12964,.,.,NA,NA,NA,NA,,
yes,AD,CCL,DN17675_c0_g2_i1,DN17675_c0_g2,CCL4_PIG,C-C motif chemokine 4,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0035690^biological_process^cellular response to drug,GO:0071346^biological_process^cellular response to interferon-gamma,.,NA,NA,NA,NA,KEGG:ssc:396668`KO:K12964,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
no,AD,CCL,DN25898_c0_g1_i5,DN25898_c0_g1,DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN25898_c1_g2_i2,DN25898_c1_g2,DCBD2_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:mmu:73379,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN25898_c1_g2_i3,DN25898_c1_g2,DCBD2_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:mmu:73379,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN25898_c1_g2_i6,DN25898_c1_g2,DCBD2_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:mmu:73379,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
yes,AD,CCL,DN2677_c0_g1_i1,DN2677_c0_g1,CCL4_PIG,C-C motif chemokine 4,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0035690^biological_process^cellular response to drug,GO:0071346^biological_process^cellular response to interferon-gamma,.,NA,NA,NA,NA,KEGG:ssc:396668`KO:K12964,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
yes,AD,CCL,DN2677_c0_g1_i3,DN2677_c0_g1,CCL3_RAT,C-C motif chemokine 3,CCL3_HUMAN,C-C motif chemokine 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0004698^molecular_function^calcium-dependent protein kinase C activity,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0004698^molecular_function^calcium-dependent protein kinase C activity,KEGG:hsa:6348`KO:K05408,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^31-86^E:2.9e-19",NA,NA,NA,NA,,
no,AD,CCL,DN39509_c0_g1_i1,DN39509_c0_g1,DCBD1_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0031638^biological_process^zymogen activation,NA,.,NA,NA,NA,NA,KEGG:mmu:66686,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i3,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00754.25^F5_F8_type_C^F5/8 type C domain^10-149^E:7.8e-28,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i10,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00431.20^CUB^CUB domain^77-189^E:5.4e-25,PF03815.19^LCCL^LCCL domain^203-281^E:2.5e-13,PF00754.25^F5_F8_type_C^F5/8 type C domain^312-451^E:5.7e-27,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i4,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i7,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i5,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i6,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00754.25^F5_F8_type_C^F5/8 type C domain^10-149^E:7.8e-28,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i2,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00754.25^F5_F8_type_C^F5/8 type C domain^3-124^E:9.7e-27,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i12,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i9,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN13371_c0_g1_i11,DN13371_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
yes,AD,CCL,DN2487_c0_g2_i1,DN2487_c0_g2,CCL4_RAT,C-C motif chemokine 4,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,.,NA,NA,NA,NA,KEGG:rno:116637`KO:K12964,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
yes,AD,CCL,DN2487_c0_g4_i1,DN2487_c0_g4,CCL14_HUMAN,C-C motif chemokine 14,.,NA,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0006874^biological_process^cellular calcium ion homeostasis,.,NA,NA,NA,NA,KEGG:hsa:6358`KO:K21092,.,.,NA,NA,NA,NA,,
yes,AD,CCL,DN31086_c0_g1_i2,DN31086_c0_g1,CCL4_BOVIN,C-C motif chemokine 4,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0035690^biological_process^cellular response to drug,GO:0071346^biological_process^cellular response to interferon-gamma,.,NA,NA,NA,NA,KEGG:bta:414347`KO:K12964,ENOG410YXJU^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
no,AD,CCL,DN21226_c0_g1_i18,DN21226_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN21226_c0_g1_i2,DN21226_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN21226_c0_g1_i6,DN21226_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,.,NA,NA,NA,NA,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN21226_c0_g1_i11,DN21226_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,.,NA,NA,NA,NA,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i6,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i5,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00431.20^CUB^CUB domain^120-227^E:5.1e-18,PF03815.19^LCCL^LCCL domain^243-321^E:2.5e-14,PF00754.25^F5_F8_type_C^F5/8 type C domain^350-491^E:1.6e-25,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i9,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i8,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i3,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i1,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i2,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00431.20^CUB^CUB domain^120-227^E:8.5e-18,PF03815.19^LCCL^LCCL domain^243-321^E:4.1e-14,PF00754.25^F5_F8_type_C^F5/8 type C domain^350-491^E:2.8e-25,NA,NA,,
no,AD,CCL,DN6484_c1_g1_i7,DN6484_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN6484_c1_g2_i1,DN6484_c1_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
yes,AD,CCL,DN9504_c0_g1_i2,DN9504_c0_g1,CCL5_HORSE,C-C motif chemokine 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031726^molecular_function^CCR1 chemokine receptor binding,GO:0031730^molecular_function^CCR5 chemokine receptor binding,.,NA,NA,NA,NA,KEGG:ecb:100033925`KO:K12499,ENOG410ZUYI^chemokine (C-C motif) ligand 5,.,NA,NA,NA,NA,,
yes,AD,CCL,DN9504_c0_g1_i1,DN9504_c0_g1,CCL5_MOUSE,C-C motif chemokine 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031726^molecular_function^CCR1 chemokine receptor binding,GO:0031730^molecular_function^CCR5 chemokine receptor binding,.,NA,NA,NA,NA,KEGG:mmu:20304`KO:K12499,ENOG410ZUYI^chemokine (C-C motif) ligand 5,.,NA,NA,NA,NA,,
yes,AD,CCL,DN9515_c0_g1_i2,DN9515_c0_g1,CCL20_MOUSE,C-C motif chemokine 20,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031731^molecular_function^CCR6 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:mmu:20297`KO:K14625,ENOG410ZGME^Chemokine (C-C motif) ligand 20,.,NA,NA,NA,NA,,
yes,AD,CCL,DN9515_c0_g1_i1,DN9515_c0_g1,CCL20_MOUSE,C-C motif chemokine 20,.,NA,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031731^molecular_function^CCR6 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:mmu:20297`KO:K14625,ENOG410ZGME^Chemokine (C-C motif) ligand 20,.,NA,NA,NA,NA,,
yes,AD,CCL,DN1013_c0_g1_i1,DN1013_c0_g1,CCL2_RAT,C-C motif chemokine 2,CCL2_RAT,C-C motif chemokine 2,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,KEGG:rno:24770`KO:K14624,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^87-136^E:1.9e-12",NA,NA,NA,NA,,
yes,AD,CCL,DN1013_c0_g1_i6,DN1013_c0_g1,CCL2_RAT,C-C motif chemokine 2,CCL2_RAT,C-C motif chemokine 2,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,KEGG:rno:24770`KO:K14624,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^87-136^E:1.9e-12",NA,NA,NA,NA,,
yes,AD,CCL,DN1013_c0_g1_i10,DN1013_c0_g1,CCL2_RAT,C-C motif chemokine 2,CCL2_RAT,C-C motif chemokine 2,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,KEGG:rno:24770`KO:K14624,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^87-136^E:1.8e-12",NA,NA,NA,NA,,
yes,AD,CCL,DN1013_c0_g1_i8,DN1013_c0_g1,CCL2_RAT,C-C motif chemokine 2,CCL2_RAT,C-C motif chemokine 2,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,GO:0043679^cellular_component^axon terminus,GO:0005737^cellular_component^cytoplasm,GO:0030425^cellular_component^dendrite,GO:0030139^cellular_component^endocytic vesicle,GO:0005615^cellular_component^extracellular space,KEGG:rno:24770`KO:K14624,ENOG410YXJU^Chemokine (C-C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^87-136^E:1.9e-12",NA,NA,NA,NA,,
yes,AD,CCL,DN32541_c0_g1_i1,DN32541_c0_g1,CCL21_MACMU,C-C motif chemokine 21,.,NA,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0031732^molecular_function^CCR7 chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,.,NA,NA,NA,NA,KEGG:mcc:574183`KO:K16062,ENOG410Z7F2^Chemokine (C-C motif) ligand,.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i10,DN5026_c0_g2,DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",DCBD1_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0031638^biological_process^zymogen activation,NA,KEGG:mmu:66686,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i13,DN5026_c0_g2,DCBD1_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0031638^biological_process^zymogen activation,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0031638^biological_process^zymogen activation,NA,KEGG:mmu:66686,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i14,DN5026_c0_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i8,DN5026_c0_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i17,DN5026_c0_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i1,DN5026_c0_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD2_RAT,"Discoidin, CUB and LCCL domain-containing protein 2",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,KEGG:rno:155696,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF00754.25^F5_F8_type_C^F5/8 type C domain^5-71^E:3.1e-13,NA,NA,NA,NA,,
no,AD,CCL,DN5026_c0_g2_i2,DN5026_c0_g2,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",PF03815.19^LCCL^LCCL domain^2-45^E:3.1e-08,PF00754.25^F5_F8_type_C^F5/8 type C domain^82-160^E:8.5e-15,NA,NA,NA,,
no,AD,CCL,DN9344_c1_g1_i2,DN9344_c1_g1,CRLD2_XENTR,Cysteine-rich secretory protein LCCL domain-containing 2,CRLD2_HUMAN,Cysteine-rich secretory protein LCCL domain-containing 2,GO:0005615^cellular_component^extracellular space,GO:0005539^molecular_function^glycosaminoglycan binding,NA,NA,NA,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:1904813^cellular_component^ficolin-1-rich granule lumen,KEGG:hsa:83716,COG2340^Scp-like extracellular,PF00188.26^CAP^Cysteine-rich secretory protein family^63-201^E:4.4e-21,PF03815.19^LCCL^LCCL domain^294-383^E:1.9e-23,PF03815.19^LCCL^LCCL domain^395-489^E:1.1e-25,NA,NA,,
no,AD,CCL,DN9344_c1_g1_i3,DN9344_c1_g1,CRLD2_XENTR,Cysteine-rich secretory protein LCCL domain-containing 2,CRLD2_HUMAN,Cysteine-rich secretory protein LCCL domain-containing 2,GO:0005615^cellular_component^extracellular space,GO:0005539^molecular_function^glycosaminoglycan binding,NA,NA,NA,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:1904813^cellular_component^ficolin-1-rich granule lumen,KEGG:hsa:83716,COG2340^Scp-like extracellular,PF00188.26^CAP^Cysteine-rich secretory protein family^63-201^E:4.4e-21,PF03815.19^LCCL^LCCL domain^294-383^E:1.9e-23,PF03815.19^LCCL^LCCL domain^395-489^E:1.1e-25,NA,NA,,
no,AD,CCL,DN9344_c1_g1_i1,DN9344_c1_g1,CRLD2_MOUSE,Cysteine-rich secretory protein LCCL domain-containing 2,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0030133^cellular_component^transport vesicle,GO:0005539^molecular_function^glycosaminoglycan binding,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:mmu:78892,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
no,AD,CCL,DN114462_c0_g1_i2,DN114462_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,PF00188.26^CAP^Cysteine-rich secretory protein family^2-123^E:1.3e-14,PF03815.19^LCCL^LCCL domain^223-313^E:1.7e-24,PF03815.19^LCCL^LCCL domain^324-418^E:5.7e-27,NA,NA,,
no,AD,CCL,DN114462_c0_g1_i3,DN114462_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
no,AD,CCL,DN114462_c0_g1_i1,DN114462_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,PF00188.26^CAP^Cysteine-rich secretory protein family^66-206^E:5e-20,PF03815.19^LCCL^LCCL domain^306-396^E:2.3e-24,PF03815.19^LCCL^LCCL domain^407-501^E:7.7e-27,NA,NA,,
no,AD,CCL,DN114462_c0_g1_i4,DN114462_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,PF00188.26^CAP^Cysteine-rich secretory protein family^66-171^E:9.6e-12,NA,NA,NA,NA,,
no,AD,CCL,DN114462_c0_g1_i5,DN114462_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,.,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
no,AD,CCL,DN101407_c1_g1_i1,DN101407_c1_g1,DCBD1_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 1",.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:285761,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN141071_c0_g1_i1,DN141071_c0_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,.,NA,NA,NA,NA,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN141071_c2_g1_i1,DN141071_c2_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,.,NA,NA,NA,NA,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN141071_c3_g1_i1,DN141071_c3_g1,DCBD2_HUMAN,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030522^biological_process^intracellular receptor signaling pathway,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,.,NA,NA,NA,NA,KEGG:hsa:131566,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN141071_c4_g1_i1,DN141071_c4_g1,DCBD2_MOUSE,"Discoidin, CUB and LCCL domain-containing protein 2",.,NA,GO:0009986^cellular_component^cell surface,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030308^biological_process^negative regulation of cell growth,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:mmu:73379,"ENOG4110JCT^Discoidin, CUB and LCCL domain containing",.,NA,NA,NA,NA,,
no,AD,CCL,DN285411_c0_g1_i1,DN285411_c0_g1,CRLD1_MOUSE,Cysteine-rich secretory protein LCCL domain-containing 1,.,NA,GO:0005615^cellular_component^extracellular space,GO:0060325^biological_process^face morphogenesis,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:83691,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
no,AD,CCL,DN202311_c0_g1_i1,DN202311_c0_g1,EF1A3_MUCCL,Elongation factor 1-alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0003746^molecular_function^translation elongation factor activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,CCL,DN377625_c0_g1_i1,DN377625_c0_g1,CRLD1_CHICK,Cysteine-rich secretory protein LCCL domain-containing 1,.,NA,GO:0005615^cellular_component^extracellular space,NA,NA,NA,NA,.,NA,NA,NA,NA,.,COG2340^Scp-like extracellular,.,NA,NA,NA,NA,,
yes,AD,CCR,DN5642_c0_g1_i13,DN5642_c0_g1,CCR7_HUMAN,C-C chemokine receptor type 7,CCR7_HUMAN,C-C chemokine receptor type 7,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:1236`KO:K04182,ENOG4110ZGY^Chemokine C-C motif receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^73-322^E:3.7e-50,NA,NA,NA,NA,,
yes,AD,CCR,DN5642_c0_g1_i10,DN5642_c0_g1,CCR7_HUMAN,C-C chemokine receptor type 7,CCR7_HUMAN,C-C chemokine receptor type 7,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:1236`KO:K04182,ENOG4110ZGY^Chemokine C-C motif receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^73-322^E:3.7e-50,NA,NA,NA,NA,,
yes,AD,CCR,DN5642_c0_g1_i3,DN5642_c0_g1,CCR7_HUMAN,C-C chemokine receptor type 7,CCR7_HUMAN,C-C chemokine receptor type 7,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:1236`KO:K04182,ENOG4110ZGY^Chemokine C-C motif receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^69-318^E:3.5e-50,NA,NA,NA,NA,,
yes,AD,CCR,DN5642_c0_g1_i12,DN5642_c0_g1,CCR7_HUMAN,C-C chemokine receptor type 7,CCR7_HUMAN,C-C chemokine receptor type 7,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:1236`KO:K04182,ENOG4110ZGY^Chemokine C-C motif receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^69-318^E:3.5e-50,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i2,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i14,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i11,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",PF13181.6^TPR_8^Tetratricopeptide repeat^12-37^E:0.0003,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i4,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",PF13181.6^TPR_8^Tetratricopeptide repeat^12-37^E:0.00045,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i3,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i6,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i1,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i9,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",PF13176.6^TPR_7^Tetratricopeptide repeat^76-100^E:0.0036,NA,NA,NA,NA,,
no,AD,CCR,DN4769_c0_g1_i5,DN4769_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN7815_c0_g1_i7,DN7815_c0_g1,PDE12_BOVIN,"2',5'-phosphodiesterase 12",PDE12_RAT,"2',5'-phosphodiesterase 12",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,KEGG:bta:538860`KO:K19612,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^289-591^E:1.9e-21,NA,NA,NA,NA,,
no,AD,CCR,DN7815_c0_g1_i5,DN7815_c0_g1,PDE12_RAT,"2',5'-phosphodiesterase 12",PDE12_RAT,"2',5'-phosphodiesterase 12",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,.,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^288-389^E:7e-07,NA,NA,NA,NA,,
no,AD,CCR,DN7801_c1_g1_i1,DN7801_c1_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,PF04153.18^NOT2_3_5^NOT2 / NOT3 / NOT5 family^456-579^E:7.7e-32,NA,NA,NA,NA,,
no,AD,CCR,DN7801_c1_g1_i5,DN7801_c1_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
no,AD,CCR,DN7801_c1_g1_i4,DN7801_c1_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
no,AD,CCR,DN7801_c1_g1_i6,DN7801_c1_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,PF04153.18^NOT2_3_5^NOT2 / NOT3 / NOT5 family^378-501^E:6.1e-32,NA,NA,NA,NA,,
no,AD,CCR,DN65277_c0_g1_i1,DN65277_c0_g1,CNO10_MACFA,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i1,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3","PF04065.15^Not3^Not1 N-terminal domain, CCR4-Not complex component^3-232^E:3.3e-96",NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i7,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,.,NA,NA,NA,NA,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3",.,NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i8,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3","PF04065.15^Not3^Not1 N-terminal domain, CCR4-Not complex component^3-232^E:2.1e-96",NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i9,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3","PF04065.15^Not3^Not1 N-terminal domain, CCR4-Not complex component^3-232^E:2.1e-96",NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i2,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3",.,NA,NA,NA,NA,,
no,AD,CCR,DN9197_c0_g1_i6,DN9197_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3","PF04065.15^Not3^Not1 N-terminal domain, CCR4-Not complex component^3-232^E:4.8e-96",NA,NA,NA,NA,,
no,AD,CCR,DN3616_c0_g1_i4,DN3616_c0_g1,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,CNO6L_MOUSE,CCR4-NOT transcription complex subunit 6-like,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,KEGG:mmu:231464`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF13516.6^LRR_6^Leucine Rich repeat^113-127^E:4.4,PF12799.7^LRR_4^Leucine Rich repeats (2 copies)^114-153^E:1.2e-07,PF13855.6^LRR_8^Leucine rich repeat^115-172^E:2.8e-11,PF00560.33^LRR_1^Leucine Rich Repeat^115-132^E:14,PF13516.6^LRR_6^Leucine Rich repeat^137-149^E:4.5,,
no,AD,CCR,DN3616_c0_g1_i2,DN3616_c0_g1,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,KEGG:hsa:246175`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN3616_c0_g1_i1,DN3616_c0_g1,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,KEGG:hsa:246175`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF13516.6^LRR_6^Leucine Rich repeat^113-127^E:4.4,PF12799.7^LRR_4^Leucine Rich repeats (2 copies)^114-153^E:1.2e-07,PF13855.6^LRR_8^Leucine rich repeat^115-172^E:2.8e-11,PF00560.33^LRR_1^Leucine Rich Repeat^115-132^E:14,PF13516.6^LRR_6^Leucine Rich repeat^137-149^E:4.5,,
no,AD,CCR,DN3676_c0_g1_i10,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_RAT,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004532^molecular_function^exoribonuclease activity,KEGG:rno:287249`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^3-120^E:1.5e-12,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i8,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,KEGG:xla:100505426`KO:K12603,.,PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^3-232^E:6.1e-13,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i9,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_HUMAN,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,KEGG:xla:100505426`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i7,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_RAT,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004532^molecular_function^exoribonuclease activity,KEGG:rno:287249`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^3-120^E:1.5e-12,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i5,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_HUMAN,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,KEGG:xla:100505426`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^3-98^E:3.8e-09,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i3,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:xla:100505426`KO:K12603,.,.,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i2,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_HUMAN,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,KEGG:xla:100505426`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g1_i4,DN3676_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,CNOT6_RAT,CCR4-NOT transcription complex subunit 6,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004532^molecular_function^exoribonuclease activity,KEGG:rno:287249`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^60-188^E:1.6e-07,NA,NA,NA,NA,,
no,AD,CCR,DN3676_c0_g2_i1,DN3676_c0_g2,CNOT6_RAT,CCR4-NOT transcription complex subunit 6,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004532^molecular_function^exoribonuclease activity,.,NA,NA,NA,NA,KEGG:rno:287249`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN6705_c0_g1_i3,DN6705_c0_g1,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,KEGG:hsa:9337`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^15-133^E:1.1e-11,PF04857.20^CAF1^CAF1 family ribonuclease^147-238^E:1.3e-09,NA,NA,NA,,
no,AD,CCR,DN6705_c0_g1_i4,DN6705_c0_g1,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,KEGG:hsa:9337`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^15-133^E:1.1e-11,PF04857.20^CAF1^CAF1 family ribonuclease^147-238^E:1.3e-09,NA,NA,NA,,
no,AD,CCR,DN6705_c0_g1_i5,DN6705_c0_g1,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,KEGG:hsa:9337`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^15-133^E:1.1e-11,PF04857.20^CAF1^CAF1 family ribonuclease^147-238^E:1.3e-09,NA,NA,NA,,
no,AD,CCR,DN14347_c0_g1_i1,DN14347_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3",PF04153.18^NOT2_3_5^NOT2 / NOT3 / NOT5 family^201-325^E:2.5e-41,NA,NA,NA,NA,,
no,AD,CCR,DN14347_c0_g1_i2,DN14347_c0_g1,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,CNOT3_HUMAN,CCR4-NOT transcription complex subunit 3,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:hsa:4849`KO:K12580,"COG5665^CCR4-NOT transcription complex, subunit 3",PF04153.18^NOT2_3_5^NOT2 / NOT3 / NOT5 family^201-256^E:7.7e-10,NA,NA,NA,NA,,
yes,AD,CCR,DN80636_c0_g1_i1,DN80636_c0_g1,CCR9_HUMAN,C-C chemokine receptor type 9,CCR9_HUMAN,C-C chemokine receptor type 9,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,KEGG:hsa:10803`KO:K04184,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^91-343^E:1.9e-45,NA,NA,NA,NA,,
no,AD,CCR,DN10087_c1_g1_i6,DN10087_c1_g1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,KEGG:hsa:23019`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",PF16417.5^CNOT1_TTP_bind^CCR4-NOT transcription complex subunit 1 TTP binding domain^99-287^E:5.7e-84,PF16415.5^CNOT1_CAF1_bind^CCR4-NOT transcription complex subunit 1 CAF1-binding domain^373-595^E:1.9e-95,PF12842.7^DUF3819^Domain of unknown function (DUF3819)^671-818^E:3.4e-54,"PF04054.15^Not1^CCR4-Not complex component, Not1^1282-1641^E:7.3e-153",NA,,
no,AD,CCR,DN10087_c1_g1_i9,DN10087_c1_g1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,KEGG:hsa:23019`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",PF16418.5^CNOT1_HEAT^CCR4-NOT transcription complex subunit 1 HEAT repeat^500-656^E:1.7e-53,PF16417.5^CNOT1_TTP_bind^CCR4-NOT transcription complex subunit 1 TTP binding domain^816-998^E:1.5e-81,PF16415.5^CNOT1_CAF1_bind^CCR4-NOT transcription complex subunit 1 CAF1-binding domain^1084-1306^E:3.1e-95,PF12842.7^DUF3819^Domain of unknown function (DUF3819)^1382-1529^E:5.3e-54,"PF04054.15^Not1^CCR4-Not complex component, Not1^1993-2352^E:1.3e-152",,
no,AD,CCR,DN10087_c1_g1_i8,DN10087_c1_g1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,KEGG:hsa:23019`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",PF16418.5^CNOT1_HEAT^CCR4-NOT transcription complex subunit 1 HEAT repeat^500-656^E:1.7e-53,PF16417.5^CNOT1_TTP_bind^CCR4-NOT transcription complex subunit 1 TTP binding domain^815-1003^E:9.2e-84,PF16415.5^CNOT1_CAF1_bind^CCR4-NOT transcription complex subunit 1 CAF1-binding domain^1089-1311^E:3.2e-95,PF12842.7^DUF3819^Domain of unknown function (DUF3819)^1387-1534^E:5.3e-54,"PF04054.15^Not1^CCR4-Not complex component, Not1^1998-2357^E:1.3e-152",,
no,AD,CCR,DN10087_c1_g1_i7,DN10087_c1_g1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,KEGG:hsa:23019`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",PF16417.5^CNOT1_TTP_bind^CCR4-NOT transcription complex subunit 1 TTP binding domain^2-176^E:7.9e-81,PF16415.5^CNOT1_CAF1_bind^CCR4-NOT transcription complex subunit 1 CAF1-binding domain^262-484^E:1.6e-95,PF12842.7^DUF3819^Domain of unknown function (DUF3819)^560-707^E:2.9e-54,"PF04054.15^Not1^CCR4-Not complex component, Not1^1171-1439^E:3.5e-95",NA,,
no,AD,CCR,DN10087_c1_g1_i5,DN10087_c1_g1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,CNOT1_HUMAN,CCR4-NOT transcription complex subunit 1,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,KEGG:hsa:23019`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",PF16417.5^CNOT1_TTP_bind^CCR4-NOT transcription complex subunit 1 TTP binding domain^2-176^E:5e-81,PF16415.5^CNOT1_CAF1_bind^CCR4-NOT transcription complex subunit 1 CAF1-binding domain^262-484^E:9.9e-96,PF12842.7^DUF3819^Domain of unknown function (DUF3819)^560-707^E:1.9e-54,NA,NA,,
no,AD,CCR,DN10087_c1_g2_i1,DN10087_c1_g2,CNOT1_XENTR,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:xtr:100036630`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN10087_c1_g2_i2,DN10087_c1_g2,CNOT1_XENTR,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:xtr:100036630`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN10034_c0_g1_i2,DN10034_c0_g1,CCR4_MOUSE,C-C chemokine receptor type 4,CCR4_MOUSE,C-C chemokine receptor type 4,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,KEGG:mmu:12773`KO:K04179,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^52-318^E:2.8e-08,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^57-305^E:1.4e-53,NA,NA,NA,,
yes,AD,CCR,DN10034_c0_g1_i1,DN10034_c0_g1,CCR4_MOUSE,C-C chemokine receptor type 4,CCR4_MOUSE,C-C chemokine receptor type 4,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,KEGG:mmu:12773`KO:K04179,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^52-318^E:2.8e-08,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^57-305^E:1.4e-53,NA,NA,NA,,
no,AD,CCR,DN66327_c0_g1_i1,DN66327_c0_g1,CNOT6_XENLA,CCR4-NOT transcription complex subunit 6,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0004532^molecular_function^exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:xla:100505426`KO:K12603,.,.,NA,NA,NA,NA,,
no,AD,CCR,DN50028_c0_g1_i1,DN50028_c0_g1,CNOT8_MOUSE,CCR4-NOT transcription complex subunit 8,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,.,NA,NA,NA,NA,KEGG:mmu:69125`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN50028_c1_g1_i5,DN50028_c1_g1,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:9337`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN50028_c1_g1_i2,DN50028_c1_g1,CNOT8_HUMAN,CCR4-NOT transcription complex subunit 8,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:9337`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN2578_c0_g1_i7,DN2578_c0_g1,CCR5_BOVIN,C-C chemokine receptor type 5,CCR5_BOVIN,C-C chemokine receptor type 5,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,KEGG:bta:497017`KO:K04180,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^47-314^E:4.2e-10,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^52-301^E:4.8e-56,NA,NA,NA,,
yes,AD,CCR,DN2578_c0_g1_i2,DN2578_c0_g1,CCR5_BOVIN,C-C chemokine receptor type 5,CCR5_BOVIN,C-C chemokine receptor type 5,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,KEGG:bta:497017`KO:K04180,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^44-310^E:7.3e-10,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^49-298^E:5.5e-54,NA,NA,NA,,
yes,AD,CCR,DN2578_c0_g1_i3,DN2578_c0_g1,CCR5_BOVIN,C-C chemokine receptor type 5,CCR5_BOVIN,C-C chemokine receptor type 5,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003779^molecular_function^actin binding,KEGG:bta:497017`KO:K04180,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^47-314^E:4.2e-10,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^52-301^E:4.8e-56,NA,NA,NA,,
no,AD,CCR,DN37731_c0_g1_i1,DN37731_c0_g1,CNOT2_MOUSE,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:72068`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
yes,AD,CCR,DN77649_c0_g1_i1,DN77649_c0_g1,CCR10_HUMAN,C-C chemokine receptor type 10,.,NA,GO:0009986^cellular_component^cell surface,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:2826`KO:K04185,ENOG4110ZGY^Chemokine C-C motif receptor,.,NA,NA,NA,NA,,
no,AD,CCR,DN92263_c0_g1_i2,DN92263_c0_g1,CNOT1_DANRE,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:dre:448949`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4185_c0_g1_i1,DN4185_c0_g1,NOCT_RAT,Nocturnin {ECO:0000312|RGD:1587344},.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,.,NA,NA,NA,NA,KEGG:rno:310395`KO:K18764,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN4185_c0_g1_i4,DN4185_c0_g1,NOCT_RAT,Nocturnin {ECO:0000312|RGD:1587344},NOCT_RAT,Nocturnin {ECO:0000312|RGD:1587344},GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,KEGG:rno:310395`KO:K18764,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN46376_c0_g1_i1,DN46376_c0_g1,CCR8_MOUSE,C-C chemokine receptor type 8,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0019956^molecular_function^chemokine binding,.,NA,NA,NA,NA,KEGG:mmu:12776`KO:K04183,ENOG410YUBT^Chemokine C-C motif receptor 8,.,NA,NA,NA,NA,,
no,AD,CCR,DN45603_c0_g1_i2,DN45603_c0_g1,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,.,NA,NA,NA,NA,KEGG:rno:301513`KO:K12606,COG5209^cell differentiation protein Rcd1,.,NA,NA,NA,NA,,
no,AD,CCR,DN77306_c0_g1_i1,DN77306_c0_g1,CNOT1_XENTR,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:xtr:100036630`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN42049_c0_g1_i7,DN42049_c0_g1,CNO11_RAT,CCR4-NOT transcription complex subunit 11,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,.,NA,NA,NA,NA,KEGG:rno:363221,ENOG410XPKT^chromosome 2 open reading frame 29,.,NA,NA,NA,NA,,
no,AD,CCR,DN42049_c0_g1_i5,DN42049_c0_g1,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",.,NA,NA,NA,NA,KEGG:hsa:55571,ENOG410XPKT^chromosome 2 open reading frame 29,.,NA,NA,NA,NA,,
no,AD,CCR,DN56720_c0_g1_i1,DN56720_c0_g1,CNO10_CHICK,CCR4-NOT transcription complex subunit 10,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006402^biological_process^mRNA catabolic process,.,NA,NA,NA,NA,KEGG:gga:420669`KO:K12607,"ENOG410XQQJ^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN13349_c0_g1_i4,DN13349_c0_g1,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,KEGG:mmu:18983`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^17-132^E:9.5e-12,PF04857.20^CAF1^CAF1 family ribonuclease^149-203^E:1e-05,NA,NA,NA,,
no,AD,CCR,DN13349_c0_g1_i6,DN13349_c0_g1,CNOT7_HUMAN,CCR4-NOT transcription complex subunit 7,CNOT7_HUMAN,CCR4-NOT transcription complex subunit 7,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0075341^cellular_component^host cell PML body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0075341^cellular_component^host cell PML body,KEGG:hsa:29883`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^17-132^E:1.7e-11,PF04857.20^CAF1^CAF1 family ribonuclease^149-238^E:1.2e-08,NA,NA,NA,,
no,AD,CCR,DN13349_c0_g1_i7,DN13349_c0_g1,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,KEGG:mmu:18983`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^17-132^E:1.2e-11,PF04857.20^CAF1^CAF1 family ribonuclease^149-204^E:8.4e-06,NA,NA,NA,,
no,AD,CCR,DN13349_c0_g1_i2,DN13349_c0_g1,CNOT7_HUMAN,CCR4-NOT transcription complex subunit 7,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0075341^cellular_component^host cell PML body,.,NA,NA,NA,NA,KEGG:hsa:29883`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN13349_c0_g1_i5,DN13349_c0_g1,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,CNOT7_MOUSE,CCR4-NOT transcription complex subunit 7,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0075341^cellular_component^host cell PML body,GO:0016604^cellular_component^nuclear body,KEGG:mmu:18983`KO:K12581,"COG5228^Ccr4-not transcription complex, subunit",PF04857.20^CAF1^CAF1 family ribonuclease^17-132^E:1e-11,PF04857.20^CAF1^CAF1 family ribonuclease^150-202^E:1.4e-05,NA,NA,NA,,
no,AD,CCR,DN60818_c0_g1_i1,DN60818_c0_g1,CNO11_RAT,CCR4-NOT transcription complex subunit 11,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,.,NA,NA,NA,NA,KEGG:rno:363221,ENOG410XPKT^chromosome 2 open reading frame 29,.,NA,NA,NA,NA,,
yes,AD,CCR,DN32880_c1_g1_i1,DN32880_c1_g1,CCR8_MOUSE,C-C chemokine receptor type 8,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0019956^molecular_function^chemokine binding,.,NA,NA,NA,NA,KEGG:mmu:12776`KO:K04183,ENOG410YUBT^Chemokine C-C motif receptor 8,.,NA,NA,NA,NA,,
yes,AD,CCR,DN2460_c0_g1_i10,DN2460_c0_g1,CCR6_MOUSE,C-C chemokine receptor type 6,CCR6_MOUSE,C-C chemokine receptor type 6,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,KEGG:mmu:12458`KO:K04181,ENOG410XSP7^Chemokine (C-C motif) receptor 6,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^41-297^E:1.7e-48,NA,NA,NA,NA,,
yes,AD,CCR,DN2460_c0_g1_i9,DN2460_c0_g1,CCR6_MOUSE,C-C chemokine receptor type 6,CCR6_MOUSE,C-C chemokine receptor type 6,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,KEGG:mmu:12458`KO:K04181,ENOG410XSP7^Chemokine (C-C motif) receptor 6,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^41-297^E:1.7e-48,NA,NA,NA,NA,,
yes,AD,CCR,DN2460_c0_g1_i4,DN2460_c0_g1,CCR6_MOUSE,C-C chemokine receptor type 6,CCR6_MOUSE,C-C chemokine receptor type 6,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,KEGG:mmu:12458`KO:K04181,ENOG410XSP7^Chemokine (C-C motif) receptor 6,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^52-308^E:1.8e-48,NA,NA,NA,NA,,
yes,AD,CCR,DN2460_c0_g1_i1,DN2460_c0_g1,CCR6_MOUSE,C-C chemokine receptor type 6,CCR6_MOUSE,C-C chemokine receptor type 6,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,KEGG:mmu:12458`KO:K04181,ENOG410XSP7^Chemokine (C-C motif) receptor 6,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^41-297^E:1.7e-48,NA,NA,NA,NA,,
yes,AD,CCR,DN2460_c0_g1_i5,DN2460_c0_g1,CCR6_MOUSE,C-C chemokine receptor type 6,CCR6_MOUSE,C-C chemokine receptor type 6,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0036126^cellular_component^sperm flagellum,GO:0097225^cellular_component^sperm midpiece,KEGG:mmu:12458`KO:K04181,ENOG410XSP7^Chemokine (C-C motif) receptor 6,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^52-308^E:1.8e-48,NA,NA,NA,NA,,
no,AD,CCR,DN22074_c0_g1_i3,DN22074_c0_g1,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN5546_c0_g1_i2,DN5546_c0_g1,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,.,NA,NA,NA,NA,KEGG:rno:301513`KO:K12606,COG5209^cell differentiation protein Rcd1,.,NA,NA,NA,NA,,
no,AD,CCR,DN5546_c0_g1_i1,DN5546_c0_g1,CNOT9_PONAB,CCR4-NOT transcription complex subunit 9 {ECO:0000250|UniProtKB:Q92600},CNOT9_RAT,CCR4-NOT transcription complex subunit 9,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0019900^molecular_function^kinase binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,KEGG:rno:301513`KO:K12606,COG5209^cell differentiation protein Rcd1,"PF04078.13^Rcd1^Cell differentiation family, Rcd1-like^25-244^E:4.1e-117",NA,NA,NA,NA,,
no,AD,CCR,DN5546_c0_g1_i9,DN5546_c0_g1,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,KEGG:rno:301513`KO:K12606,COG5209^cell differentiation protein Rcd1,"PF04078.13^Rcd1^Cell differentiation family, Rcd1-like^17-275^E:1.2e-134",NA,NA,NA,NA,,
no,AD,CCR,DN5546_c0_g1_i5,DN5546_c0_g1,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,CNOT9_RAT,CCR4-NOT transcription complex subunit 9,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,KEGG:rno:301513`KO:K12606,COG5209^cell differentiation protein Rcd1,"PF04078.13^Rcd1^Cell differentiation family, Rcd1-like^1-190^E:1.4e-104",NA,NA,NA,NA,,
no,AD,CCR,DN10557_c0_g1_i4,DN10557_c0_g1,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",KEGG:hsa:55571,ENOG410XPKT^chromosome 2 open reading frame 29,PF10155.9^CNOT11^CCR4-NOT transcription complex subunit 11^334-376^E:4e-11,NA,NA,NA,NA,,
no,AD,CCR,DN10557_c0_g1_i12,DN10557_c0_g1,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,CNO11_RAT,CCR4-NOT transcription complex subunit 11,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,KEGG:rno:363221,ENOG410XPKT^chromosome 2 open reading frame 29,PF10155.9^CNOT11^CCR4-NOT transcription complex subunit 11^50-101^E:2.1e-23,NA,NA,NA,NA,,
no,AD,CCR,DN10557_c0_g1_i11,DN10557_c0_g1,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,CNO11_RAT,CCR4-NOT transcription complex subunit 11,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,KEGG:rno:363221,ENOG410XPKT^chromosome 2 open reading frame 29,PF10155.9^CNOT11^CCR4-NOT transcription complex subunit 11^50-101^E:2.1e-23,NA,NA,NA,NA,,
no,AD,CCR,DN10557_c0_g1_i3,DN10557_c0_g1,CNO11_RAT,CCR4-NOT transcription complex subunit 11,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0031047^biological_process^gene silencing by RNA,GO:0006417^biological_process^regulation of translation,.,NA,NA,NA,NA,KEGG:rno:363221,ENOG410XPKT^chromosome 2 open reading frame 29,.,NA,NA,NA,NA,,
no,AD,CCR,DN10557_c0_g1_i7,DN10557_c0_g1,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,CNO11_HUMAN,CCR4-NOT transcription complex subunit 11,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008283^biological_process^cell population proliferation,"GO:0006977^biological_process^DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",KEGG:hsa:55571,ENOG410XPKT^chromosome 2 open reading frame 29,PF10155.9^CNOT11^CCR4-NOT transcription complex subunit 11^334-458^E:9.6e-55,NA,NA,NA,NA,,
no,AD,CCR,DN43198_c1_g1_i1,DN43198_c1_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
no,AD,CCR,DN9577_c0_g1_i2,DN9577_c0_g1,ANGE1_HUMAN,Protein angel homolog 1,.,NA,GO:0005801^cellular_component^cis-Golgi network,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,.,NA,NA,NA,NA,KEGG:hsa:23357`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN9577_c0_g1_i1,DN9577_c0_g1,ANGE1_RAT,Protein angel homolog 1 {ECO:0000312|RGD:1306238},ANGE1_HUMAN,Protein angel homolog 1,GO:0005801^cellular_component^cis-Golgi network,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005801^cellular_component^cis-Golgi network,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:23357`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN65063_c0_g1_i1,DN65063_c0_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
no,AD,CCR,DN40773_c0_g1_i6,DN40773_c0_g1,CNOT9_PONAB,CCR4-NOT transcription complex subunit 9 {ECO:0000250|UniProtKB:Q92600},.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0019900^molecular_function^kinase binding,.,NA,NA,NA,NA,KEGG:pon:100173439`KO:K12606,COG5209^cell differentiation protein Rcd1,.,NA,NA,NA,NA,,
no,AD,CCR,DN31634_c0_g1_i1,DN31634_c0_g1,CNOT2_MOUSE,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:72068`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
no,AD,CCR,DN35539_c0_g1_i5,DN35539_c0_g1,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN35539_c0_g1_i10,DN35539_c0_g1,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN35539_c0_g1_i4,DN35539_c0_g1,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN35539_c0_g1_i7,DN35539_c0_g1,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i7,DN17573_c0_g1,ANGE2_HUMAN,Protein angel homolog 2,ANGE2_HUMAN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:hsa:90806`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i6,DN17573_c0_g1,ANGE2_HUMAN,Protein angel homolog 2,.,NA,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,.,NA,NA,NA,NA,KEGG:hsa:90806`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i9,DN17573_c0_g1,ANGE2_HUMAN,Protein angel homolog 2,.,NA,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,.,NA,NA,NA,NA,KEGG:hsa:90806`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i11,DN17573_c0_g1,ANGE2_BOVIN,Protein angel homolog 2,ANGE2_BOVIN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:bta:540507`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^4-218^E:1.1e-09,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i4,DN17573_c0_g1,ANGE2_BOVIN,Protein angel homolog 2,ANGE2_BOVIN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:bta:540507`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^4-218^E:1.1e-09,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i3,DN17573_c0_g1,ANGE2_BOVIN,Protein angel homolog 2,ANGE2_BOVIN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:bta:540507`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^4-218^E:9.3e-10,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g1_i8,DN17573_c0_g1,ANGE2_HUMAN,Protein angel homolog 2,.,NA,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,.,NA,NA,NA,NA,KEGG:hsa:90806`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g2_i1,DN17573_c0_g2,ANGE2_BOVIN,Protein angel homolog 2,ANGE2_BOVIN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:bta:540507`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^245-369^E:3.7e-11,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g2_i2,DN17573_c0_g2,ANGE2_BOVIN,Protein angel homolog 2,ANGE2_BOVIN,Protein angel homolog 2,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,KEGG:bta:540507`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",PF03372.23^Exo_endo_phos^Endonuclease/Exonuclease/phosphatase family^183-307^E:2.5e-11,NA,NA,NA,NA,,
no,AD,CCR,DN17573_c0_g3_i1,DN17573_c0_g3,ANGE2_HUMAN,Protein angel homolog 2,.,NA,GO:0015030^cellular_component^Cajal body,GO:0005737^cellular_component^cytoplasm,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070935^biological_process^3'-UTR-mediated mRNA stabilization,.,NA,NA,NA,NA,KEGG:hsa:90806`KO:K18729,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN1684_c2_g2_i6,DN1684_c2_g2,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN1684_c2_g2_i12,DN1684_c2_g2,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN1684_c2_g2_i8,DN1684_c2_g2,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN1684_c2_g2_i9,DN1684_c2_g2,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,PF14570.6^zf-RING_4^RING/Ubox like zinc-binding domain^65-111^E:6.2e-20,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^181-238^E:1.9e-05",NA,NA,NA,,
no,AD,CCR,DN1684_c2_g2_i4,DN1684_c2_g2,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,CNOT4_HUMAN,CCR4-NOT transcription complex subunit 4,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:4850`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN29552_c0_g1_i1,DN29552_c0_g1,PDE12_RAT,"2',5'-phosphodiesterase 12",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,.,NA,NA,NA,NA,.,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN29552_c0_g1_i3,DN29552_c0_g1,PDE12_RAT,"2',5'-phosphodiesterase 12",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,.,NA,NA,NA,NA,.,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN29552_c0_g2_i1,DN29552_c0_g2,PDE12_RAT,"2',5'-phosphodiesterase 12",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,GO:0004535^molecular_function^poly(A)-specific ribonuclease activity,.,NA,NA,NA,NA,.,"COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN182168_c0_g1_i1,DN182168_c0_g1,CNO6L_MOUSE,CCR4-NOT transcription complex subunit 6-like,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,.,NA,NA,NA,NA,KEGG:mmu:231464`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN142100_c0_g1_i1,DN142100_c0_g1,CNO6L_DANRE,CCR4-NOT transcription complex subunit 6-like,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:dre:553665`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN142100_c1_g1_i1,DN142100_c1_g1,CNO6L_HUMAN,CCR4-NOT transcription complex subunit 6-like,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,.,NA,NA,NA,NA,KEGG:hsa:246175`KO:K12603,"COG4886^leucine Rich Repeat`COG5239^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN110783_c0_g1_i1,DN110783_c0_g1,CNOT1_DANRE,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:dre:448949`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN292404_c0_g1_i1,DN292404_c0_g1,CNOT1_MOUSE,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,.,NA,NA,NA,NA,KEGG:mmu:234594`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN272920_c0_g1_i1,DN272920_c0_g1,CNOT4_MOUSE,CCR4-NOT transcription complex subunit 4,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:mmu:53621`KO:K10643,COG5175^CCR4-NOT transcription complex subunit 4,.,NA,NA,NA,NA,,
no,AD,CCR,DN296775_c0_g1_i1,DN296775_c0_g1,CNOT1_XENTR,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:xtr:100036630`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN245783_c0_g1_i1,DN245783_c0_g1,CCR8_HUMAN,C-C chemokine receptor type 8,CCR8_HUMAN,C-C chemokine receptor type 8,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,KEGG:hsa:1237`KO:K04183,ENOG410YUBT^Chemokine C-C motif receptor 8,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^2-151^E:2e-05,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^4-191^E:4.5e-32,NA,NA,NA,,
no,AD,CCR,DN208533_c0_g1_i1,DN208533_c0_g1,CNOT1_MOUSE,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,.,NA,NA,NA,NA,KEGG:mmu:234594`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN223633_c0_g1_i1,DN223633_c0_g1,CCR9_HUMAN,C-C chemokine receptor type 9,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,.,NA,NA,NA,NA,KEGG:hsa:10803`KO:K04184,ENOG410XRW9^Receptor,.,NA,NA,NA,NA,,
no,AD,CCR,DN216953_c0_g1_i1,DN216953_c0_g1,CNOT1_DANRE,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:dre:448949`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
yes,AD,CCR,DN352445_c0_g1_i1,DN352445_c0_g1,CCR9_HUMAN,C-C chemokine receptor type 9,.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,.,NA,NA,NA,NA,KEGG:hsa:10803`KO:K04184,ENOG410XRW9^Receptor,.,NA,NA,NA,NA,,
no,AD,CCR,DN397359_c0_g1_i1,DN397359_c0_g1,CNOT7_XENLA,CCR4-NOT transcription complex subunit 7,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004532^molecular_function^exoribonuclease activity,.,NA,NA,NA,NA,KEGG:xla:734751`KO:K12581,.,.,NA,NA,NA,NA,,
yes,AD,CCR,DN354500_c0_g1_i1,DN354500_c0_g1,.,NA,CCR8_MOUSE,C-C chemokine receptor type 8,.,NA,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0016493^molecular_function^C-C chemokine receptor activity,GO:0019956^molecular_function^chemokine binding,KEGG:mmu:12776`KO:K04183,ENOG410YUBT^Chemokine C-C motif receptor 8,.,NA,NA,NA,NA,,
yes,AD,CCR,DN364882_c0_g1_i1,DN364882_c0_g1,CCR4_HUMAN,C-C chemokine receptor type 4,CCR4_HUMAN,C-C chemokine receptor type 4,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043025^cellular_component^neuronal cell body,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043025^cellular_component^neuronal cell body,GO:0005886^cellular_component^plasma membrane,GO:0019957^molecular_function^C-C chemokine binding,KEGG:hsa:1233`KO:K04179,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^76-116^E:7.6e-08,NA,NA,NA,NA,,
no,AD,CCR,DN428725_c0_g1_i1,DN428725_c0_g1,CNOT1_XENTR,CCR4-NOT transcription complex subunit 1,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005634^cellular_component^nucleus,GO:0000932^cellular_component^P-body,GO:0030331^molecular_function^estrogen receptor binding,.,NA,NA,NA,NA,KEGG:xtr:100036630`KO:K12604,"COG5103^Ccr4-NOT transcription complex, subunit",.,NA,NA,NA,NA,,
no,AD,CCR,DN464228_c0_g1_i1,DN464228_c0_g1,CNOT2_HUMAN,CCR4-NOT transcription complex subunit 2,.,NA,GO:0030014^cellular_component^CCR4-NOT complex,GO:0030015^cellular_component^CCR4-NOT core complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:4848`KO:K12605,COG5601^CCR4-NOT transcription complex subunit 2,.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i7,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,.,NA,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,NA,NA,NA,NA,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i8,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",PF16681.5^Ig_5^Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain^44-114^E:2.6e-08,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i3,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i2,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,.,NA,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,NA,NA,NA,NA,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i12,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,.,NA,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,NA,NA,NA,NA,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i5,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",PF16681.5^Ig_5^Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain^45-114^E:9.3e-08,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i6,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,.,NA,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,NA,NA,NA,NA,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",.,NA,NA,NA,NA,,
yes,AD,CD3E,DN35_c0_g1_i10,DN35_c0_g1,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,CD3E_CHICK,T-cell surface glycoprotein CD3 epsilon chain,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0042105^cellular_component^alpha-beta T cell receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,.,"ENOG41123JN^CD3e molecule, epsilon (CD3-TCR complex)",PF16681.5^Ig_5^Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain^16-85^E:7.1e-08,NA,NA,NA,NA,,
no,AD,CD3E,DN3945_c0_g2_i1,DN3945_c0_g2,RPA34_MOUSE,DNA-directed RNA polymerase I subunit RPA34,RPA34_MOUSE,DNA-directed RNA polymerase I subunit RPA34,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,KEGG:mmu:70333,"ENOG4112CGI^CD3e molecule, epsilon associated protein",PF08208.11^RNA_polI_A34^DNA-directed RNA polymerase I subunit RPA34.5^46-155^E:2.4e-11,NA,NA,NA,NA,,
no,AD,CD4,DN62252_c1_g1_i1,DN62252_c1_g1,CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,.,NA,NA,NA,NA,,
no,AD,CD4,DN43459_c0_g1_i2,DN43459_c0_g1,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,NA,NA,NA,NA,.,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,CD4,DN6076_c2_g2_i1,DN6076_c2_g2,ITA2_HUMAN,Integrin alpha-2,ITA2_HUMAN,Integrin alpha-2,GO:0043679^cellular_component^axon terminus,GO:0045178^cellular_component^basal part of cell,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005925^cellular_component^focal adhesion,GO:0043679^cellular_component^axon terminus,GO:0045178^cellular_component^basal part of cell,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005925^cellular_component^focal adhesion,KEGG:hsa:3673`KO:K06481,"ENOG4110534^integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)",PF00092.28^VWA^von Willebrand factor type A domain^202-378^E:4.4e-41,PF13519.6^VWA_2^von Willebrand factor type A domain^203-313^E:2.2e-14,PF01839.23^FG-GAP^FG-GAP repeat^518-555^E:4.8e-05,PF01839.23^FG-GAP^FG-GAP repeat^584-616^E:1.3e-06,PF08441.12^Integrin_alpha2^Integrin alpha^696-1068^E:1.1e-45,,
no,AD,CD4,DN6076_c2_g2_i2,DN6076_c2_g2,ITA2_HUMAN,Integrin alpha-2,ITA2_BOVIN,Integrin alpha-2,GO:0043679^cellular_component^axon terminus,GO:0045178^cellular_component^basal part of cell,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005925^cellular_component^focal adhesion,GO:0008305^cellular_component^integrin complex,GO:0046872^molecular_function^metal ion binding,GO:0007155^biological_process^cell adhesion,GO:0007229^biological_process^integrin-mediated signaling pathway,NA,KEGG:hsa:3673`KO:K06481,"ENOG4110534^integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN5146_c0_g1_i9,DN5146_c0_g1,TNR5_MOUSE,Tumor necrosis factor receptor superfamily member 5,.,NA,GO:0035631^cellular_component^CD40 receptor complex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:mmu:21939`KO:K03160,"ENOG4112DB5^CD40 molecule, TNF receptor superfamily member 5",.,NA,NA,NA,NA,,
no,AD,CD4,DN5146_c0_g1_i2,DN5146_c0_g1,TNR5_MOUSE,Tumor necrosis factor receptor superfamily member 5,.,NA,GO:0035631^cellular_component^CD40 receptor complex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:mmu:21939`KO:K03160,"ENOG4112DB5^CD40 molecule, TNF receptor superfamily member 5",.,NA,NA,NA,NA,,
no,AD,CD4,DN5146_c0_g1_i10,DN5146_c0_g1,TNR5_MOUSE,Tumor necrosis factor receptor superfamily member 5,TNR5_MOUSE,Tumor necrosis factor receptor superfamily member 5,GO:0035631^cellular_component^CD40 receptor complex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0035631^cellular_component^CD40 receptor complex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:21939`KO:K03160,"ENOG4112DB5^CD40 molecule, TNF receptor superfamily member 5",PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^26-59^E:0.00034,PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^62-103^E:1.7e-06,PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^147-187^E:7.7e-07,NA,NA,,
no,AD,CD4,DN5146_c0_g1_i3,DN5146_c0_g1,TNR5_MOUSE,Tumor necrosis factor receptor superfamily member 5,.,NA,GO:0035631^cellular_component^CD40 receptor complex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:mmu:21939`KO:K03160,"ENOG4112DB5^CD40 molecule, TNF receptor superfamily member 5",.,NA,NA,NA,NA,,
yes,AD,CD4,DN23348_c0_g1_i1,DN23348_c0_g1,CD40L_CHICK,CD40 ligand,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:gga:395485`KO:K03161,ENOG4111TET^CD40 ligand,.,NA,NA,NA,NA,,
yes,AD,CD4,DN23348_c0_g1_i4,DN23348_c0_g1,CD40L_CHICK,CD40 ligand,CD40L_CHICK,CD40 ligand,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:gga:395485`KO:K03161,ENOG4111TET^CD40 ligand,PF00229.18^TNF^TNF(Tumour Necrosis Factor) family^100-220^E:1.2e-29,NA,NA,NA,NA,,
yes,AD,CD4,DN23348_c0_g1_i2,DN23348_c0_g1,CD40L_CHICK,CD40 ligand,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:gga:395485`KO:K03161,ENOG4111TET^CD40 ligand,.,NA,NA,NA,NA,,
yes,AD,CD4,DN23348_c0_g1_i3,DN23348_c0_g1,CD40L_CHICK,CD40 ligand,CD40L_CHICK,CD40 ligand,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,KEGG:gga:395485`KO:K03161,ENOG4111TET^CD40 ligand,PF00229.18^TNF^TNF(Tumour Necrosis Factor) family^169-289^E:2.4e-29,NA,NA,NA,NA,,
no,AD,CD4,DN61770_c0_g1_i1,DN61770_c0_g1,TBCD4_MOUSE,TBC1 domain family member 4,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,.,NA,NA,NA,NA,KEGG:mmu:210789`KO:K17902,ENOG410YWJY^ecotropic viral integration site,.,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g1_i6,DN13016_c0_g1,CCD47_HUMAN,Coiled-coil domain-containing protein 47,CCD47_MOUSE,Coiled-coil domain-containing protein 47,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,PF07946.14^DUF1682^Protein of unknown function (DUF1682)^134-341^E:4.5e-60,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g1_i7,DN13016_c0_g1,CCD47_HUMAN,Coiled-coil domain-containing protein 47,CCD47_MOUSE,Coiled-coil domain-containing protein 47,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,PF07946.14^DUF1682^Protein of unknown function (DUF1682)^136-468^E:8.9e-93,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g1_i1,DN13016_c0_g1,CCD47_HUMAN,Coiled-coil domain-containing protein 47,CCD47_MOUSE,Coiled-coil domain-containing protein 47,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,PF07946.14^DUF1682^Protein of unknown function (DUF1682)^134-341^E:4.5e-60,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g1_i4,DN13016_c0_g1,CCD47_HUMAN,Coiled-coil domain-containing protein 47,CCD47_MOUSE,Coiled-coil domain-containing protein 47,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,PF07946.14^DUF1682^Protein of unknown function (DUF1682)^1-92^E:2.3e-19,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g1_i8,DN13016_c0_g1,CCD47_HUMAN,Coiled-coil domain-containing protein 47,CCD47_MOUSE,Coiled-coil domain-containing protein 47,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,PF07946.14^DUF1682^Protein of unknown function (DUF1682)^134-341^E:4.5e-60,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g2_i1,DN13016_c0_g2,CCD47_MACFA,Coiled-coil domain-containing protein 47,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0032469^biological_process^endoplasmic reticulum calcium ion homeostasis,GO:0036503^biological_process^ERAD pathway,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN13016_c0_g3_i1,DN13016_c0_g3,CCD47_MOUSE,Coiled-coil domain-containing protein 47,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0055074^biological_process^calcium ion homeostasis,.,NA,NA,NA,NA,KEGG:mmu:67163,ENOG410XREM^Coiled-coil domain containing 47,.,NA,NA,NA,NA,,
no,AD,CD4,DN93047_c0_g1_i1,DN93047_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i6,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,PDCD4_RAT,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,KEGG:rno:64031`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^237-347^E:1.9e-18,PF02847.17^MA3^MA3 domain^401-511^E:6.1e-21,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i1,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,PDCD4_RAT,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,KEGG:rno:64031`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^111-221^E:1.3e-21,NA,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i7,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^198-308^E:7.6e-19,NA,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i3,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,KEGG:rno:64031`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),.,NA,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i2,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^198-308^E:1.7e-18,PF02847.17^MA3^MA3 domain^362-472^E:5.4e-21,NA,NA,NA,,
no,AD,CD4,DN4191_c1_g1_i4,DN4191_c1_g1,PDCD4_RAT,Programmed cell death protein 4,PDCD4_RAT,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0006915^biological_process^apoptotic process,KEGG:rno:64031`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^90-200^E:1.1e-21,NA,NA,NA,NA,,
yes,AD,CD4,DN4178_c0_g1_i5,DN4178_c0_g1,CD48_HUMAN,CD48 antigen,CD48_HUMAN,CD48 antigen,GO:0031225^cellular_component^anchored component of membrane,GO:0070062^cellular_component^extracellular exosome,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0045121^cellular_component^membrane raft,GO:0031225^cellular_component^anchored component of membrane,GO:0070062^cellular_component^extracellular exosome,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0045121^cellular_component^membrane raft,KEGG:hsa:962`KO:K06479,ENOG410ZR3T^mast cell activation,.,NA,NA,NA,NA,,
yes,AD,CD4,DN4178_c0_g1_i13,DN4178_c0_g1,CD48_HUMAN,CD48 antigen,SLAF8_MOUSE,SLAM family member 8,GO:0031225^cellular_component^anchored component of membrane,GO:0070062^cellular_component^extracellular exosome,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0045121^cellular_component^membrane raft,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0042802^molecular_function^identical protein binding,GO:0038023^molecular_function^signaling receptor activity,GO:0002336^biological_process^B-1 B cell lineage commitment,KEGG:mmu:74748`KO:K16853,ENOG410Y74Q^receptor activity,.,NA,NA,NA,NA,,
no,AD,CD4,DN55309_c0_g1_i6,DN55309_c0_g1,ITA4_HUMAN,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,.,NA,NA,NA,NA,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN55309_c0_g1_i7,DN55309_c0_g1,ITA4_HUMAN,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,.,NA,NA,NA,NA,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN37290_c0_g1_i1,DN37290_c0_g1,CCD47_DANRE,Coiled-coil domain-containing protein 47,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,.,NA,NA,NA,NA,KEGG:dre:447812,ENOG410XREM^Coiled-coil domain containing 47,.,NA,NA,NA,NA,,
no,AD,CD4,DN37290_c0_g1_i2,DN37290_c0_g1,CCD47_DANRE,Coiled-coil domain-containing protein 47,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,.,NA,NA,NA,NA,KEGG:dre:447812,ENOG410XREM^Coiled-coil domain containing 47,.,NA,NA,NA,NA,,
no,AD,CD4,DN9043_c0_g1_i4,DN9043_c0_g1,CCD43_CHICK,Coiled-coil domain-containing protein 43,.,NA,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:419971,ENOG4111JC7^Coiled-coil domain containing 43,.,NA,NA,NA,NA,,
no,AD,CD4,DN9043_c0_g1_i1,DN9043_c0_g1,CCD43_CHICK,Coiled-coil domain-containing protein 43,CCD43_CHICK,Coiled-coil domain-containing protein 43,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,KEGG:gga:419971,ENOG4111JC7^Coiled-coil domain containing 43,.,NA,NA,NA,NA,,
no,AD,CD4,DN9043_c0_g1_i3,DN9043_c0_g1,CCD43_CHICK,Coiled-coil domain-containing protein 43,.,NA,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:419971,ENOG4111JC7^Coiled-coil domain containing 43,.,NA,NA,NA,NA,,
no,AD,CD4,DN9043_c0_g1_i2,DN9043_c0_g1,CCD43_CHICK,Coiled-coil domain-containing protein 43,.,NA,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:419971,ENOG4111JC7^Coiled-coil domain containing 43,.,NA,NA,NA,NA,,
no,AD,CD4,DN9043_c0_g2_i1,DN9043_c0_g2,CCD43_CHICK,Coiled-coil domain-containing protein 43,.,NA,GO:0005829^cellular_component^cytosol,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:419971,ENOG4111JC7^Coiled-coil domain containing 43,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i8,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,KEGG:xla:735225`KO:K05857,.,PF00168.30^C2^C2 domain^2-52^E:8.6e-09,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i10,DN8113_c0_g1,PLCD4_PIG,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:ssc:397119`KO:K05857,ENOG410XPSW^phospholipase c,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i11,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i14,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i6,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,KEGG:xla:735225`KO:K05857,.,PF00168.30^C2^C2 domain^74-126^E:3.7e-09,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i1,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i3,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i5,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,KEGG:xla:735225`KO:K05857,.,PF13499.6^EF-hand_7^EF-hand domain pair^9-72^E:5.4e-07,PF13202.6^EF-hand_5^EF hand^11-34^E:0.00018,PF14788.6^EF-hand_10^EF hand^25-74^E:1.9e-20,"PF09279.11^EF-hand_like^Phosphoinositide-specific phospholipase C, efhand-like^70-155^E:5.4e-38","PF00388.19^PI-PLC-X^Phosphatidylinositol-specific phospholipase C, X domain^164-308^E:2.4e-63",,
no,AD,CD4,DN8113_c0_g1_i9,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,.,NA,NA,NA,NA,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN8113_c0_g1_i12,DN8113_c0_g1,PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",PLCD4_XENLA,"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4",GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0004435^molecular_function^phosphatidylinositol phospholipase C activity,KEGG:xla:735225`KO:K05857,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i6,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF11830.8^DUF3350^Domain of unknown function (DUF3350)^59-122^E:2e-30,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i1,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00566.18^RabGAP-TBC^Rab-GTPase-TBC domain^65-273^E:6.6e-53,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i7,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00566.18^RabGAP-TBC^Rab-GTPase-TBC domain^17-225^E:4.9e-53,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i5,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF11830.8^DUF3350^Domain of unknown function (DUF3350)^59-122^E:3.2e-29,PF00566.18^RabGAP-TBC^Rab-GTPase-TBC domain^182-390^E:1.2e-52,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i4,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00566.18^RabGAP-TBC^Rab-GTPase-TBC domain^17-225^E:4.9e-53,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g1_i3,DN6314_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00566.18^RabGAP-TBC^Rab-GTPase-TBC domain^17-225^E:4.9e-53,NA,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g2_i1,DN6314_c0_g2,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_MOUSE,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,KEGG:mmu:210789`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00640.23^PID^Phosphotyrosine interaction domain (PTB/PID)^111-175^E:0.00031,PF00640.23^PID^Phosphotyrosine interaction domain (PTB/PID)^338-438^E:9.2e-07,PF11830.8^DUF3350^Domain of unknown function (DUF3350)^736-797^E:6.3e-28,NA,NA,,
no,AD,CD4,DN6314_c0_g2_i3,DN6314_c0_g2,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00640.23^PID^Phosphotyrosine interaction domain (PTB/PID)^111-175^E:0.00022,PF00640.23^PID^Phosphotyrosine interaction domain (PTB/PID)^338-438^E:6.1e-07,NA,NA,NA,,
no,AD,CD4,DN6314_c0_g2_i4,DN6314_c0_g2,TBCD4_HUMAN,TBC1 domain family member 4,TBCD4_HUMAN,TBC1 domain family member 4,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,PF00640.23^PID^Phosphotyrosine interaction domain (PTB/PID)^338-438^E:1e-06,PF11830.8^DUF3350^Domain of unknown function (DUF3350)^786-847^E:6.8e-28,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i1,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^163-258^E:6.8e-16,NA,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i3,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^163-272^E:5.1e-20,PF02847.17^MA3^MA3 domain^327-365^E:4.7e-07,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i7,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,.,NA,NA,NA,NA,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),.,NA,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i6,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^163-272^E:5.1e-20,PF02847.17^MA3^MA3 domain^327-365^E:4.7e-07,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i8,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^163-272^E:5.1e-20,PF02847.17^MA3^MA3 domain^327-365^E:4.7e-07,NA,NA,NA,,
no,AD,CD4,DN2694_c0_g1_i4,DN2694_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,PDCD4_CHICK,Programmed cell death protein 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),PF02847.17^MA3^MA3 domain^37-147^E:1.5e-26,NA,NA,NA,NA,,
no,AD,CD4,DN13393_c0_g1_i1,DN13393_c0_g1,CD48D_ARATH,Cell division control protein 48 homolog D,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:ath:AT3G53230`KO:K13525,COG0464^Aaa atpase,.,NA,NA,NA,NA,,
no,AD,CD4,DN20775_c0_g1_i3,DN20775_c0_g1,CCD42_HUMAN,Coiled-coil domain-containing protein 42 {ECO:0000305},CC42M_XENLA,Coiled-coil domain-containing protein 42 like-2 {ECO:0000305},GO:0007286^biological_process^spermatid development,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:146849,ENOG4111NGK^coiledcoil domain containing,.,NA,NA,NA,NA,,
yes,AD,CD4,DN1227_c1_g1_i2,DN1227_c1_g1,CD47_PIG,Leukocyte surface antigen CD47,CD47_PIG,Leukocyte surface antigen CD47,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,KEGG:ssc:397042`KO:K06266,ENOG41113GI^Cd47 molecule,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^39-162^E:5.4e-36,NA,NA,NA,NA,,
yes,AD,CD4,DN1227_c1_g1_i1,DN1227_c1_g1,CD47_PIG,Leukocyte surface antigen CD47,CD47_PIG,Leukocyte surface antigen CD47,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,KEGG:ssc:397042`KO:K06266,ENOG41113GI^Cd47 molecule,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^39-162^E:5.4e-36,NA,NA,NA,NA,,
yes,AD,CD4,DN1227_c1_g1_i6,DN1227_c1_g1,CD47_BOVIN,Leukocyte surface antigen CD47,CD47_PIG,Leukocyte surface antigen CD47,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,KEGG:ssc:397042`KO:K06266,ENOG41113GI^Cd47 molecule,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^39-162^E:3.1e-35,PF04549.14^CD47^CD47 transmembrane region^189-335^E:8.1e-39,NA,NA,NA,,
yes,AD,CD4,DN1227_c1_g1_i5,DN1227_c1_g1,CD47_PIG,Leukocyte surface antigen CD47,CD47_PIG,Leukocyte surface antigen CD47,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,KEGG:ssc:397042`KO:K06266,ENOG41113GI^Cd47 molecule,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^39-167^E:1.4e-35,PF04549.14^CD47^CD47 transmembrane region^173-319^E:7.3e-39,NA,NA,NA,,
yes,AD,CD4,DN1227_c1_g1_i3,DN1227_c1_g1,CD47_PIG,Leukocyte surface antigen CD47,CD47_PIG,Leukocyte surface antigen CD47,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0070053^molecular_function^thrombospondin receptor activity,GO:0007155^biological_process^cell adhesion,GO:0022409^biological_process^positive regulation of cell-cell adhesion,KEGG:ssc:397042`KO:K06266,ENOG41113GI^Cd47 molecule,PF08204.11^V-set_CD47^CD47 immunoglobulin-like domain^39-162^E:5.4e-36,NA,NA,NA,NA,,
yes,AD,CD4,DN25447_c3_g1_i1,DN25447_c3_g1,CD40L_CHICK,CD40 ligand,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005174^molecular_function^CD40 receptor binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:gga:395485`KO:K03161,ENOG4111TET^CD40 ligand,.,NA,NA,NA,NA,,
no,AD,CD4,DN39151_c0_g1_i1,DN39151_c0_g1,ITA4_MOUSE,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,.,NA,NA,NA,NA,KEGG:mmu:16401`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN2411_c0_g2_i7,DN2411_c0_g2,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,MSI1H_RAT,RNA-binding protein Musashi homolog 1,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005844^cellular_component^polysome,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003723^molecular_function^RNA binding,KEGG:rno:259272`KO:K14411,ENOG410YA8Z^Rna-binding protein,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^79-117^E:4.9e-09",NA,NA,NA,NA,,
no,AD,CD4,DN2411_c0_g2_i5,DN2411_c0_g2,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,COG5184^regulator of chromosome condensation,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^8-74^E:6.6e-14",PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^4255-4587^E:7.9e-41,NA,NA,NA,,
no,AD,CD4,DN2411_c0_g2_i6,DN2411_c0_g2,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,COG5184^regulator of chromosome condensation,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^43-109^E:6.6e-14",PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^4290-4622^E:8e-41,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i3,DN7346_c0_g1,CD44_MOUSE,CD44 antigen,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:mmu:12505`KO:K06256,ENOG4111S6T^CD44 molecule (Indian blood group),.,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i9,DN7346_c0_g1,CD44_MOUSE,CD44 antigen,CD44_MOUSE,CD44 antigen,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,KEGG:mmu:12505`KO:K06256,ENOG4111S6T^CD44 molecule (Indian blood group),PF00193.17^Xlink^Extracellular link domain^33-120^E:3.1e-20,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i4,DN7346_c0_g1,CD44_PAPHA,CD44 antigen,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0031258^cellular_component^lamellipodium membrane,GO:0005902^cellular_component^microvillus,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i7,DN7346_c0_g1,CD44_PAPHA,CD44 antigen,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0031258^cellular_component^lamellipodium membrane,GO:0005902^cellular_component^microvillus,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i8,DN7346_c0_g1,CD44_MOUSE,CD44 antigen,CD44_MOUSE,CD44 antigen,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,KEGG:mmu:12505`KO:K06256,ENOG4111S6T^CD44 molecule (Indian blood group),PF00193.17^Xlink^Extracellular link domain^33-120^E:3.5e-20,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i6,DN7346_c0_g1,CD44_PAPHA,CD44 antigen,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0031258^cellular_component^lamellipodium membrane,GO:0005902^cellular_component^microvillus,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,CD4,DN7346_c0_g1_i1,DN7346_c0_g1,CD44_MOUSE,CD44 antigen,CD44_PAPHA,CD44 antigen,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0042995^cellular_component^cell projection,GO:0009986^cellular_component^cell surface,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0031258^cellular_component^lamellipodium membrane,GO:0005902^cellular_component^microvillus,KEGG:mmu:12505`KO:K06256,ENOG4111S6T^CD44 molecule (Indian blood group),PF00193.17^Xlink^Extracellular link domain^33-120^E:4.7e-20,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g1_i2,DN17815_c1_g1,CCD40_MOUSE,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0031514^cellular_component^motile cilium,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,.,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g1_i12,DN17815_c1_g1,CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,PF08647.11^BRE1^BRE1 E3 ubiquitin ligase^612-710^E:1.3e-20,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g1_i3,DN17815_c1_g1,CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,PF08647.11^BRE1^BRE1 E3 ubiquitin ligase^545-643^E:9.1e-21,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g1_i6,DN17815_c1_g1,CCD40_MOUSE,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0031514^cellular_component^motile cilium,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,PF08647.11^BRE1^BRE1 E3 ubiquitin ligase^178-271^E:1e-19,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g1_i7,DN17815_c1_g1,CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_HUMAN,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0070286^biological_process^axonemal dynein complex assembly,KEGG:hsa:55036,ENOG410XTIY^coiled-coil domain containing 40,PF08647.11^BRE1^BRE1 E3 ubiquitin ligase^178-276^E:2.4e-21,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g2_i1,DN17815_c1_g2,CCD40_MOUSE,Coiled-coil domain-containing protein 40 {ECO:0000305},.,NA,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0031514^cellular_component^motile cilium,.,NA,NA,NA,NA,.,ENOG410XTIY^coiled-coil domain containing 40,.,NA,NA,NA,NA,,
no,AD,CD4,DN17815_c1_g4_i1,DN17815_c1_g4,CCD40_MOUSE,Coiled-coil domain-containing protein 40 {ECO:0000305},CCD40_MOUSE,Coiled-coil domain-containing protein 40 {ECO:0000305},GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0031514^cellular_component^motile cilium,GO:0005930^cellular_component^axoneme,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0031514^cellular_component^motile cilium,.,ENOG410XTIY^coiled-coil domain containing 40,.,NA,NA,NA,NA,,
no,AD,CD4,DN1881_c0_g1_i7,DN1881_c0_g1,ITA4_MOUSE,Integrin alpha-4,ITA4_HUMAN,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",PF01839.23^FG-GAP^FG-GAP repeat^120-156^E:6.3e-10,"PF13517.6^VCBS^Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella^128-201^E:1.8e-08",PF01839.23^FG-GAP^FG-GAP repeat^185-217^E:6.4e-07,NA,NA,,
no,AD,CD4,DN1881_c0_g1_i2,DN1881_c0_g1,ITA4_HUMAN,Integrin alpha-4,ITA4_HUMAN,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN1881_c0_g1_i9,DN1881_c0_g1,ITA4_HUMAN,Integrin alpha-4,ITA4_HUMAN,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",PF01839.23^FG-GAP^FG-GAP repeat^328-364^E:3.9e-09,"PF13517.6^VCBS^Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella^336-409^E:1.3e-07",PF01839.23^FG-GAP^FG-GAP repeat^393-425^E:3.8e-06,PF08441.12^Integrin_alpha2^Integrin alpha^485-885^E:8.3e-76,PF00357.20^Integrin_alpha^Integrin alpha cytoplasmic region^1021-1031^E:0.0019,,
no,AD,CD4,DN1881_c0_g1_i8,DN1881_c0_g1,ITA4_HUMAN,Integrin alpha-4,ITA4_MOUSE,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,KEGG:mmu:16401`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",PF08441.12^Integrin_alpha2^Integrin alpha^3-63^E:3.6e-05,PF00357.20^Integrin_alpha^Integrin alpha cytoplasmic region^199-209^E:0.00033,NA,NA,NA,,
no,AD,CD4,DN1881_c0_g1_i3,DN1881_c0_g1,ITA4_HUMAN,Integrin alpha-4,ITA4_HUMAN,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",PF01839.23^FG-GAP^FG-GAP repeat^328-364^E:2.6e-09,"PF13517.6^VCBS^Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella^336-409^E:8.4e-08",PF01839.23^FG-GAP^FG-GAP repeat^393-425^E:2.6e-06,PF08441.12^Integrin_alpha2^Integrin alpha^485-742^E:9.4e-54,NA,,
no,AD,CD4,DN1881_c0_g1_i1,DN1881_c0_g1,ITA4_MOUSE,Integrin alpha-4,ITA4_HUMAN,Integrin alpha-4,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",PF01839.23^FG-GAP^FG-GAP repeat^133-169^E:3.1e-09,"PF13517.6^VCBS^Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella^141-214^E:9.9e-08",PF01839.23^FG-GAP^FG-GAP repeat^198-230^E:3e-06,PF08441.12^Integrin_alpha2^Integrin alpha^290-690^E:5e-76,PF00357.20^Integrin_alpha^Integrin alpha cytoplasmic region^826-836^E:0.0015,,
no,AD,CD4,DN1881_c0_g1_i5,DN1881_c0_g1,ITA4_MOUSE,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,.,NA,NA,NA,NA,KEGG:mmu:16401`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN1881_c0_g1_i4,DN1881_c0_g1,ITA4_HUMAN,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0070062^cellular_component^extracellular exosome,GO:0005925^cellular_component^focal adhesion,GO:0030426^cellular_component^growth cone,GO:0034669^cellular_component^integrin alpha4-beta7 complex,.,NA,NA,NA,NA,KEGG:hsa:3676`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN5889_c0_g1_i1,DN5889_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,.,NA,NA,NA,NA,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),.,NA,NA,NA,NA,,
no,AD,CD4,DN1362_c0_g1_i3,DN1362_c0_g1,ITA3_BOVIN,Integrin alpha-3,ITA3_BOVIN,Integrin alpha-3,GO:0016323^cellular_component^basolateral plasma membrane,GO:0030054^cellular_component^cell junction,GO:0060076^cellular_component^excitatory synapse,GO:0009897^cellular_component^external side of plasma membrane,GO:0031527^cellular_component^filopodium membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0030054^cellular_component^cell junction,GO:0060076^cellular_component^excitatory synapse,GO:0009897^cellular_component^external side of plasma membrane,GO:0031527^cellular_component^filopodium membrane,KEGG:bta:508490`KO:K06482,"ENOG410ZZD8^integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)",PF01839.23^FG-GAP^FG-GAP repeat^306-344^E:1.9e-11,"PF13517.6^VCBS^Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella^314-387^E:7e-10",PF01839.23^FG-GAP^FG-GAP repeat^371-404^E:3.9e-09,PF01839.23^FG-GAP^FG-GAP repeat^432-453^E:9.1e-05,PF08441.12^Integrin_alpha2^Integrin alpha^464-917^E:2.2e-92,,
no,AD,CD4,DN7105_c0_g1_i3,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i6,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i2,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i8,DN7105_c0_g1,HACD4_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^86-113^E:0.00017",NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i7,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^11-93^E:3.9e-15",NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i4,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,CD4,DN7105_c0_g1_i9,DN7105_c0_g1,HACD4_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:401494`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i12,DN7181_c0_g1,ABCD4_HUMAN,ATP-binding cassette sub-family D member 4,.,NA,GO:0043190^cellular_component^ATP-binding cassette (ABC) transporter complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005778^cellular_component^peroxisomal membrane,.,NA,NA,NA,NA,KEGG:hsa:5826`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i7,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,PF06472.15^ABC_membrane_2^ABC transporter transmembrane region 2^2-135^E:1.9e-36,PF00005.27^ABC_tran^ABC transporter^245-392^E:1.9e-16,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i5,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i11,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,PF06472.15^ABC_membrane_2^ABC transporter transmembrane region 2^34-299^E:6.1e-80,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i1,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i8,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,PF00005.27^ABC_tran^ABC transporter^2-135^E:3.3e-13,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i2,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i13,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i3,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,ABCD4_HUMAN,ATP-binding cassette sub-family D member 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,GO:0043190^cellular_component^ATP-binding cassette (ABC) transporter complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005778^cellular_component^peroxisomal membrane,KEGG:hsa:5826`KO:K05678,COG4178^(ABC) transporter,PF00005.27^ABC_tran^ABC transporter^62-101^E:1.9e-07,PF05783.11^DLIC^Dynein light intermediate chain (DLIC)^68-102^E:0.028,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i4,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i6,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,.,NA,NA,NA,NA,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g1_i16,DN7181_c0_g1,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,ABCD4_MOUSE,ATP-binding cassette sub-family D member 4,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0042626^molecular_function^ATPase-coupled transmembrane transporter activity,KEGG:mmu:19300`KO:K05678,COG4178^(ABC) transporter,PF06472.15^ABC_membrane_2^ABC transporter transmembrane region 2^34-299^E:6.1e-80,NA,NA,NA,NA,,
no,AD,CD4,DN7181_c0_g2_i1,DN7181_c0_g2,ABCD4_HUMAN,ATP-binding cassette sub-family D member 4,.,NA,GO:0043190^cellular_component^ATP-binding cassette (ABC) transporter complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005778^cellular_component^peroxisomal membrane,.,NA,NA,NA,NA,KEGG:hsa:5826`KO:K05678,COG4178^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,CD4,DN33909_c0_g1_i1,DN33909_c0_g1,TBCD4_MOUSE,TBC1 domain family member 4,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,.,NA,NA,NA,NA,KEGG:mmu:210789`KO:K17902,ENOG410YWJY^ecotropic viral integration site,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i9,DN15963_c0_g1,CD4_RABIT,T-cell surface glycoprotein CD4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0015026^molecular_function^coreceptor activity,GO:0002250^biological_process^adaptive immune response,GO:0007155^biological_process^cell adhesion,.,NA,NA,NA,NA,KEGG:ocu:100009152`KO:K06454,.,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i5,DN15963_c0_g1,CD4_PANTR,T-cell surface glycoprotein CD4,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045121^cellular_component^membrane raft,.,NA,NA,NA,NA,KEGG:ptr:450124`KO:K06454,ENOG410YWI4^induction by virus of host cell-cell fusion,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i4,DN15963_c0_g1,CD4_RAT,T-cell surface glycoprotein CD4,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045121^cellular_component^membrane raft,GO:0005886^cellular_component^plasma membrane,GO:0015026^molecular_function^coreceptor activity,.,NA,NA,NA,NA,KEGG:rno:24932`KO:K06454,ENOG410YWI4^induction by virus of host cell-cell fusion,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i7,DN15963_c0_g1,CD4_PANTR,T-cell surface glycoprotein CD4,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045121^cellular_component^membrane raft,.,NA,NA,NA,NA,KEGG:ptr:450124`KO:K06454,ENOG410YWI4^induction by virus of host cell-cell fusion,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i8,DN15963_c0_g1,CD4_PANTR,T-cell surface glycoprotein CD4,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045121^cellular_component^membrane raft,.,NA,NA,NA,NA,KEGG:ptr:450124`KO:K06454,ENOG410YWI4^induction by virus of host cell-cell fusion,.,NA,NA,NA,NA,,
yes,AD,CD4,DN15963_c0_g1_i1,DN15963_c0_g1,.,NA,CD4_DELLE,T-cell surface glycoprotein CD4,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0015026^molecular_function^coreceptor activity,GO:0002250^biological_process^adaptive immune response,GO:0007155^biological_process^cell adhesion,.,.,.,NA,NA,NA,NA,,
no,AD,CD4,DN74713_c0_g1_i2,DN74713_c0_g1,TBCD4_MOUSE,TBC1 domain family member 4,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,.,NA,NA,NA,NA,KEGG:mmu:210789`KO:K17902,ENOG410YWJY^ecotropic viral integration site,.,NA,NA,NA,NA,,
no,AD,CD4,DN81174_c0_g1_i1,DN81174_c0_g1,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-44^E:3.6e-05,NA,NA,NA,NA,,
no,AD,CD4,DN81174_c1_g1_i1,DN81174_c1_g1,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,NA,NA,NA,NA,.,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,CD4,DN190309_c0_g1_i1,DN190309_c0_g1,TBCD4_MOUSE,TBC1 domain family member 4,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,.,NA,NA,NA,NA,KEGG:mmu:210789`KO:K17902,ENOG410YWJY^ecotropic viral integration site,.,NA,NA,NA,NA,,
no,AD,CD4,DN146247_c0_g1_i7,DN146247_c0_g1,CC42M_XENLA,Coiled-coil domain-containing protein 42 like-2 {ECO:0000305},CCD42_HUMAN,Coiled-coil domain-containing protein 42 {ECO:0000305},.,NA,NA,NA,NA,GO:0007286^biological_process^spermatid development,NA,NA,NA,NA,KEGG:hsa:146849,ENOG4111NGK^coiledcoil domain containing,.,NA,NA,NA,NA,,
no,AD,CD4,DN146247_c0_g1_i8,DN146247_c0_g1,.,NA,CCD42_HUMAN,Coiled-coil domain-containing protein 42 {ECO:0000305},.,NA,NA,NA,NA,GO:0007286^biological_process^spermatid development,NA,NA,NA,NA,KEGG:hsa:146849,ENOG4111NGK^coiledcoil domain containing,.,NA,NA,NA,NA,,
no,AD,CD4,DN111807_c0_g1_i1,DN111807_c0_g1,TBCD4_HUMAN,TBC1 domain family member 4,.,NA,GO:0005829^cellular_component^cytosol,GO:0031982^cellular_component^vesicle,GO:0005096^molecular_function^GTPase activator activity,GO:0017137^molecular_function^Rab GTPase binding,GO:0090630^biological_process^activation of GTPase activity,.,NA,NA,NA,NA,KEGG:hsa:9882`KO:K17902,ENOG410YWJY^ecotropic viral integration site,.,NA,NA,NA,NA,,
no,AD,CD4,DN187128_c0_g1_i1,DN187128_c0_g1,PDCD4_CHICK,Programmed cell death protein 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0007569^biological_process^cell aging,.,NA,NA,NA,NA,KEGG:gga:374191`KO:K16865,ENOG410XQZZ^programmed cell death 4 (Neoplastic transformation inhibitor),.,NA,NA,NA,NA,,
no,AD,CD4,DN222753_c0_g1_i1,DN222753_c0_g1,ITA3_HUMAN,Integrin alpha-3,.,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0071944^cellular_component^cell periphery,GO:0009986^cellular_component^cell surface,GO:0060076^cellular_component^excitatory synapse,GO:0009897^cellular_component^external side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:3675`KO:K06482,"ENOG410ZZD8^integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN269606_c0_g1_i1,DN269606_c0_g1,ITA2_HUMAN,Integrin alpha-2,.,NA,GO:0043679^cellular_component^axon terminus,GO:0045178^cellular_component^basal part of cell,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005925^cellular_component^focal adhesion,.,NA,NA,NA,NA,KEGG:hsa:3673`KO:K06481,"ENOG4110534^integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)",.,NA,NA,NA,NA,,
no,AD,CD4,DN237140_c0_g1_i1,DN237140_c0_g1,HECD4_HUMAN,Probable E3 ubiquitin-protein ligase HECTD4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0042593^biological_process^glucose homeostasis,GO:0006006^biological_process^glucose metabolic process,NA,.,NA,NA,NA,NA,.,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,CD4,DN441892_c0_g1_i1,DN441892_c0_g1,ITA4_MOUSE,Integrin alpha-4,.,NA,GO:0009986^cellular_component^cell surface,GO:0005911^cellular_component^cell-cell junction,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0030426^cellular_component^growth cone,.,NA,NA,NA,NA,KEGG:mmu:16401`KO:K06483,"ENOG410XTAR^Integrin, alpha 4 (Antigen CD49D, alpha 4 subunit of VLA-4 receptor)",.,NA,NA,NA,NA,,
yes,AD,CD59,DN1551_c1_g1_i6,DN1551_c1_g1,CD59_PAPSP,CD59 glycoprotein,CD59_MACFA,CD59 glycoprotein,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,.,.,PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^27-94^E:0.61,NA,NA,NA,NA,,
yes,AD,CD59,DN1551_c1_g1_i1,DN1551_c1_g1,CD59_PAPSP,CD59 glycoprotein,CD59_MACFA,CD59 glycoprotein,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,.,.,PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^27-94^E:0.61,NA,NA,NA,NA,,
yes,AD,CD59,DN1551_c1_g1_i3,DN1551_c1_g1,CD59_PAPSP,CD59 glycoprotein,CD59_PAPSP,CD59 glycoprotein,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,CD59,DN1551_c1_g1_i2,DN1551_c1_g1,CD59_PAPSP,CD59 glycoprotein,CD59_MACFA,CD59 glycoprotein,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0001971^biological_process^negative regulation of activation of membrane attack complex,NA,NA,.,.,PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^27-94^E:0.61,NA,NA,NA,NA,,
yes,AD,CD8A,DN279_c0_g2_i3,DN279_c0_g2,CD8A_BOVIN,T-cell surface glycoprotein CD8 alpha chain,CD8A_BOVIN,T-cell surface glycoprotein CD8 alpha chain,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0045065^biological_process^cytotoxic T cell differentiation,GO:0002456^biological_process^T cell mediated immunity,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0045065^biological_process^cytotoxic T cell differentiation,GO:0002456^biological_process^T cell mediated immunity,KEGG:bta:281060`KO:K06458,ENOG410Z6EI^CD8a molecule,PF07686.17^V-set^Immunoglobulin V-set domain^76-175^E:3.9e-11,NA,NA,NA,NA,,
yes,AD,CD8A,DN279_c0_g2_i4,DN279_c0_g2,.,NA,CD8A_RAT,T-cell surface glycoprotein CD8 alpha chain,.,NA,NA,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0044853^cellular_component^plasma membrane raft,GO:0023024^molecular_function^MHC class I protein complex binding,GO:0019901^molecular_function^protein kinase binding,KEGG:rno:24930`KO:K06458,ENOG410Z6EI^CD8a molecule,PF07686.17^V-set^Immunoglobulin V-set domain^76-174^E:3.7e-11,NA,NA,NA,NA,,
yes,AD,CD8A,DN279_c0_g2_i8,DN279_c0_g2,.,NA,CD8A_MOUSE,T-cell surface glycoprotein CD8 alpha chain,.,NA,NA,NA,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0044853^cellular_component^plasma membrane raft,KEGG:mmu:12525`KO:K06458,ENOG410Z6EI^CD8a molecule,PF07686.17^V-set^Immunoglobulin V-set domain^76-175^E:3.5e-11,NA,NA,NA,NA,,
no,AD,CDH,DN33541_c0_g1_i2,DN33541_c0_g1,HCDH_HUMAN,"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:3033`KO:K00022,.,.,NA,NA,NA,NA,,
yes,AD,CDH,DN39095_c0_g1_i1,DN39095_c0_g1,CDHR4_HUMAN,Cadherin-related family member 4,CDHR4_HUMAN,Cadherin-related family member 4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:hsa:389118`KO:K16504,ENOG4110NJ5^cadherin-related family member 4,PF00028.17^Cadherin^Cadherin domain^139-201^E:3.4e-07,NA,NA,NA,NA,,
yes,AD,CDH,DN39095_c0_g1_i2,DN39095_c0_g1,CDHR4_HUMAN,Cadherin-related family member 4,CDHR4_HUMAN,Cadherin-related family member 4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:hsa:389118`KO:K16504,ENOG4110NJ5^cadherin-related family member 4,PF00028.17^Cadherin^Cadherin domain^196-258^E:5.6e-07,NA,NA,NA,NA,,
yes,AD,CDH,DN21010_c0_g1_i4,DN21010_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF08374.11^Protocadherin^Protocadherin^8-85^E:1.6e-36,NA,NA,NA,NA,,
yes,AD,CDH,DN3688_c0_g1_i1,DN3688_c0_g1,PCDH1_HUMAN,Protocadherin-1,PCDH1_HUMAN,Protocadherin-1,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,KEGG:hsa:5097`KO:K16498,ENOG410XPHP^Protocadherin,PF00028.17^Cadherin^Cadherin domain^1-86^E:2.5e-16,PF00028.17^Cadherin^Cadherin domain^110-192^E:3.1e-15,PF08374.11^Protocadherin^Protocadherin^195-408^E:6.1e-82,NA,NA,,
yes,AD,CDH,DN3688_c0_g1_i2,DN3688_c0_g1,PCDH1_HUMAN,Protocadherin-1,PCDH1_HUMAN,Protocadherin-1,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,KEGG:hsa:5097`KO:K16498,ENOG410XPHP^Protocadherin,PF00028.17^Cadherin^Cadherin domain^1-86^E:4.2e-16,PF00028.17^Cadherin^Cadherin domain^110-192^E:5.2e-15,PF08374.11^Protocadherin^Protocadherin^195-408^E:1.3e-81,NA,NA,,
yes,AD,CDH,DN3688_c0_g1_i5,DN3688_c0_g1,PCDH1_HUMAN,Protocadherin-1,PCDH9_HUMAN,Protocadherin-9,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,CDH,DN4081_c4_g1_i2,DN4081_c4_g1,HCDH_PIG,"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial",HCDH_MOUSE,"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0070403^molecular_function^NAD+ binding,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0005737^cellular_component^cytoplasm,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:15107`KO:K00022,COG1250^Dehydrogenase,PF07992.14^Pyr_redox_2^Pyridine nucleotide-disulphide oxidoreductase^61-124^E:3.5e-06,"PF02737.18^3HCDH_N^3-hydroxyacyl-CoA dehydrogenase, NAD binding domain^73-258^E:8.3e-63",PF00070.27^Pyr_redox^Pyridine nucleotide-disulphide oxidoreductase^73-150^E:1.5e-05,"PF00725.22^3HCDH^3-hydroxyacyl-CoA dehydrogenase, C-terminal domain^260-357^E:7.9e-34",NA,,
yes,AD,CDH,DN48225_c0_g1_i2,DN48225_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF08374.11^Protocadherin^Protocadherin^55-266^E:1.5e-88,NA,NA,NA,NA,,
yes,AD,CDH,DN48225_c0_g1_i3,DN48225_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF08374.11^Protocadherin^Protocadherin^55-266^E:7.7e-89,NA,NA,NA,NA,,
yes,AD,CDH,DN48225_c0_g1_i1,DN48225_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF08374.11^Protocadherin^Protocadherin^55-266^E:3.5e-89,NA,NA,NA,NA,,
yes,AD,CDH,DN2127_c0_g1_i5,DN2127_c0_g1,CDHR5_HUMAN,Cadherin-related family member 5 {ECO:0000305},.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0070062^cellular_component^extracellular exosome,GO:0031528^cellular_component^microvillus membrane,.,NA,NA,NA,NA,KEGG:hsa:53841`KO:K16505,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN2127_c0_g1_i6,DN2127_c0_g1,CDHR5_MOUSE,Cadherin-related family member 5 {ECO:0000305},CDHR5_HUMAN,Cadherin-related family member 5 {ECO:0000305},GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031528^cellular_component^microvillus membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0070062^cellular_component^extracellular exosome,GO:0031528^cellular_component^microvillus membrane,KEGG:hsa:53841`KO:K16505,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN2127_c0_g1_i4,DN2127_c0_g1,CDHR5_HUMAN,Cadherin-related family member 5 {ECO:0000305},.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0070062^cellular_component^extracellular exosome,GO:0031528^cellular_component^microvillus membrane,.,NA,NA,NA,NA,KEGG:hsa:53841`KO:K16505,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN2127_c0_g1_i7,DN2127_c0_g1,CDHR5_HUMAN,Cadherin-related family member 5 {ECO:0000305},CDHR5_RAT,Cadherin-related family member 5 {ECO:0000305},GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0070062^cellular_component^extracellular exosome,GO:0031528^cellular_component^microvillus membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,KEGG:rno:171554`KO:K16505,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN2127_c0_g1_i9,DN2127_c0_g1,CDHR5_RAT,Cadherin-related family member 5 {ECO:0000305},CDHR5_HUMAN,Cadherin-related family member 5 {ECO:0000305},GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0031526^cellular_component^brush border membrane,GO:0005905^cellular_component^clathrin-coated pit,GO:0070062^cellular_component^extracellular exosome,GO:0031528^cellular_component^microvillus membrane,KEGG:hsa:53841`KO:K16505,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN72845_c0_g1_i1,DN72845_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF00028.17^Cadherin^Cadherin domain^39-82^E:1.4e-07,NA,NA,NA,NA,,
yes,AD,CDH,DN4664_c1_g1_i1,DN4664_c1_g1,PCDH1_HUMAN,Protocadherin-1,PCDH1_HUMAN,Protocadherin-1,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005911^cellular_component^cell-cell junction,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005730^cellular_component^nucleolus,KEGG:hsa:5097`KO:K16498,ENOG410XPHP^Protocadherin,PF08266.12^Cadherin_2^Cadherin-like^87-167^E:1.2e-05,PF00028.17^Cadherin^Cadherin domain^202-297^E:9.3e-14,PF00028.17^Cadherin^Cadherin domain^312-404^E:4e-19,PF00028.17^Cadherin^Cadherin domain^429-523^E:1.8e-13,PF00028.17^Cadherin^Cadherin domain^540-629^E:3.5e-23,,
yes,AD,CDH,DN94902_c0_g1_i2,DN94902_c0_g1,CDHR4_HUMAN,Cadherin-related family member 4,CDHR4_HUMAN,Cadherin-related family member 4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:hsa:389118`KO:K16504,ENOG4110NJ5^cadherin-related family member 4,PF00028.17^Cadherin^Cadherin domain^73-165^E:3.1e-11,NA,NA,NA,NA,,
yes,AD,CDH,DN94902_c0_g1_i1,DN94902_c0_g1,CDHR4_HUMAN,Cadherin-related family member 4,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:hsa:389118`KO:K16504,ENOG4110NJ5^cadherin-related family member 4,.,NA,NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i33,DN1810_c0_g1,GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,KEGG:mmu:270076`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^1-73^E:9.2e-18","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^77-171^E:2.3e-20","PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^189-330^E:1.4e-31","PF08028.11^Acyl-CoA_dh_2^Acyl-CoA dehydrogenase, C-terminal domain^198-318^E:9e-08",NA,,
no,AD,CDH,DN1810_c0_g1_i4,DN1810_c0_g1,GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,KEGG:bta:506310`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^64-174^E:8.4e-27","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^178-272^E:2e-20",NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i15,DN1810_c0_g1,GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_MACFA,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0033539^biological_process^fatty acid beta-oxidation using acyl-CoA dehydrogenase,KEGG:mcf:102119324`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^1-90^E:1.3e-12",NA,NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i31,DN1810_c0_g1,GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_MACFA,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0033539^biological_process^fatty acid beta-oxidation using acyl-CoA dehydrogenase,KEGG:mcf:102119324`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^29-141^E:6.6e-22",NA,NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i11,DN1810_c0_g1,GCDH_HUMAN,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_HUMAN,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0004361^molecular_function^glutaryl-CoA dehydrogenase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0004361^molecular_function^glutaryl-CoA dehydrogenase activity,KEGG:hsa:2639`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^2-82^E:5.3e-21",NA,NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i26,DN1810_c0_g1,GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,KEGG:bta:506310`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^64-174^E:1.8e-26","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^178-272^E:4.1e-20","PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^290-419^E:2.1e-27","PF08028.11^Acyl-CoA_dh_2^Acyl-CoA dehydrogenase, C-terminal domain^299-418^E:2.6e-07",NA,,
no,AD,CDH,DN1810_c0_g1_i20,DN1810_c0_g1,GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,KEGG:bta:506310`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^98-208^E:1.8e-26","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^212-306^E:4.1e-20","PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^324-465^E:2.8e-31","PF08028.11^Acyl-CoA_dh_2^Acyl-CoA dehydrogenase, C-terminal domain^333-453^E:1.4e-07",NA,,
no,AD,CDH,DN1810_c0_g1_i2,DN1810_c0_g1,GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_BOVIN,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003995^molecular_function^acyl-CoA dehydrogenase activity,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0044466^molecular_function^glutaryl-CoA hydrolase activity,KEGG:bta:506310`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^64-174^E:1e-26","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^178-272^E:2.4e-20",NA,NA,NA,,
no,AD,CDH,DN1810_c0_g1_i12,DN1810_c0_g1,GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GCDH_MOUSE,"Glutaryl-CoA dehydrogenase, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0000062^molecular_function^fatty-acyl-CoA binding,GO:0050660^molecular_function^flavin adenine dinucleotide binding,KEGG:mmu:270076`KO:K00252,COG1960^acyl-CoA dehydrogenase,"PF02771.16^Acyl-CoA_dh_N^Acyl-CoA dehydrogenase, N-terminal domain^1-73^E:9.2e-18","PF02770.19^Acyl-CoA_dh_M^Acyl-CoA dehydrogenase, middle domain^77-171^E:2.3e-20","PF00441.24^Acyl-CoA_dh_1^Acyl-CoA dehydrogenase, C-terminal domain^189-330^E:1.4e-31","PF08028.11^Acyl-CoA_dh_2^Acyl-CoA dehydrogenase, C-terminal domain^198-318^E:9e-08",NA,,
yes,AD,CDH,DN1818_c2_g1_i5,DN1818_c2_g1,CDHR2_HUMAN,Cadherin-related family member 2 {ECO:0000305},.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005903^cellular_component^brush border,GO:0031526^cellular_component^brush border membrane,GO:0030054^cellular_component^cell junction,GO:0070062^cellular_component^extracellular exosome,.,NA,NA,NA,NA,KEGG:hsa:54825`KO:K16502,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN27206_c0_g1_i2,DN27206_c0_g1,PCDH3_RAT,Protocadherin-3,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:rno:25133`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN27206_c0_g1_i1,DN27206_c0_g1,PCDH3_RAT,Protocadherin-3,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:rno:25133`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN1669_c0_g1_i1,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^9-99^E:7.8e-09,PF00028.17^Cadherin^Cadherin domain^233-322^E:1.8e-15,PF00028.17^Cadherin^Cadherin domain^335-433^E:1.7e-09,NA,NA,,
yes,AD,CDH,DN1669_c0_g1_i10,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^90-188^E:2.9e-16,PF00028.17^Cadherin^Cadherin domain^204-294^E:1.6e-08,PF00028.17^Cadherin^Cadherin domain^428-517^E:3.6e-15,PF00028.17^Cadherin^Cadherin domain^530-628^E:3.5e-09,NA,,
yes,AD,CDH,DN1669_c0_g1_i3,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^5-77^E:6.5e-08,PF00028.17^Cadherin^Cadherin domain^102-200^E:2.4e-16,PF00028.17^Cadherin^Cadherin domain^216-306^E:1.3e-08,PF00028.17^Cadherin^Cadherin domain^440-529^E:3e-15,PF00028.17^Cadherin^Cadherin domain^542-640^E:2.9e-09,,
yes,AD,CDH,DN1669_c0_g1_i2,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN1669_c0_g1_i7,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN1669_c0_g1_i9,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN1669_c0_g1_i4,DN1669_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,CDHR1_CHICK,Cadherin-related family member 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN195331_c0_g1_i1,DN195331_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN153304_c0_g1_i3,DN153304_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF00028.17^Cadherin^Cadherin domain^11-62^E:6e-09,PF00028.17^Cadherin^Cadherin domain^87-183^E:5.9e-12,NA,NA,NA,,
yes,AD,CDH,DN283153_c0_g1_i1,DN283153_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^2-45^E:8.2e-08,NA,NA,NA,NA,,
yes,AD,CDH,DN251582_c0_g1_i1,DN251582_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF08374.11^Protocadherin^Protocadherin^23-143^E:2.2e-39,NA,NA,NA,NA,,
yes,AD,CDH,DN266146_c0_g1_i1,DN266146_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^1-95^E:6.3e-14,PF00028.17^Cadherin^Cadherin domain^112-181^E:2.7e-14,NA,NA,NA,,
yes,AD,CDH,DN266373_c0_g1_i1,DN266373_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF08266.12^Cadherin_2^Cadherin-like^6-84^E:7.3e-07,NA,NA,NA,NA,,
yes,AD,CDH,DN399278_c0_g1_i1,DN399278_c0_g1,PCDH8_RAT,Protocadherin-8,PCDH8_RAT,Protocadherin-8,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0099055^cellular_component^integral component of postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0099055^cellular_component^integral component of postsynaptic membrane,KEGG:rno:64865`KO:K16499,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^28-102^E:6.6e-13,NA,NA,NA,NA,,
yes,AD,CDH,DN313022_c0_g1_i1,DN313022_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF08266.12^Cadherin_2^Cadherin-like^44-124^E:4.5e-08,NA,NA,NA,NA,,
yes,AD,CDH,DN367983_c0_g1_i1,DN367983_c0_g1,CDHR3_HUMAN,Cadherin-related family member 3,CDHR3_HUMAN,Cadherin-related family member 3,GO:0016342^cellular_component^catenin complex,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0016342^cellular_component^catenin complex,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:222256`KO:K16503,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN321485_c0_g1_i1,DN321485_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^54-142^E:6.1e-11,NA,NA,NA,NA,,
yes,AD,CDH,DN443135_c0_g1_i1,DN443135_c0_g1,CDHR3_HUMAN,Cadherin-related family member 3,CDHR3_HUMAN,Cadherin-related family member 3,GO:0016342^cellular_component^catenin complex,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0016342^cellular_component^catenin complex,GO:0009986^cellular_component^cell surface,GO:0005913^cellular_component^cell-cell adherens junction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:222256`KO:K16503,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,CDH,DN424482_c0_g1_i1,DN424482_c0_g1,HCDH_HUMAN,"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:3033`KO:K00022,.,.,NA,NA,NA,NA,,
yes,AD,CDH,DN453046_c0_g1_i1,DN453046_c0_g1,PCDH9_HUMAN,Protocadherin-9,PCDH9_HUMAN,Protocadherin-9,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0044291^cellular_component^cell-cell contact zone,GO:0030426^cellular_component^growth cone,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5101`KO:K16498,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^57-103^E:2.7e-08,NA,NA,NA,NA,,
yes,AD,CDH,DN407139_c0_g1_i1,DN407139_c0_g1,CDHR1_CHICK,Cadherin-related family member 1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:gga:414847`KO:K16501,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
yes,AD,CDH,DN429497_c0_g1_i1,DN429497_c0_g1,PCDH7_HUMAN,Protocadherin-7,PCDH7_HUMAN,Protocadherin-7,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,KEGG:hsa:5099`KO:K16498,ENOG410XPHP^Protocadherin,PF00028.17^Cadherin^Cadherin domain^5-60^E:5.8e-14,PF00028.17^Cadherin^Cadherin domain^75-168^E:1.3e-19,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i1,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i11,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^8-97^E:1.9e-20",PF01396.19^zf-C4_Topoisom^Topoisomerase DNA binding C4 zinc finger^39-53^E:0.065,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i4,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i15,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i9,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i13,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^31-119^E:3.3e-19",PF01396.19^zf-C4_Topoisom^Topoisomerase DNA binding C4 zinc finger^62-76^E:0.27,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i3,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN4204_c0_g1_i2,DN4204_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^31-119^E:4.1e-19",PF01396.19^zf-C4_Topoisom^Topoisomerase DNA binding C4 zinc finger^62-76^E:0.31,NA,NA,NA,,
no,AD,CSF,DN4355_c0_g1_i3,DN4355_c0_g1,ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,KEGG:hsa:197322`KO:K18660,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^100-525^E:2.3e-80,NA,NA,NA,NA,,
no,AD,CSF,DN4355_c0_g1_i1,DN4355_c0_g1,ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,KEGG:hsa:197322`KO:K18660,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^100-525^E:2.9e-80,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^541-578^E:4.2e-06,NA,NA,NA,,
no,AD,CSF,DN4355_c0_g1_i2,DN4355_c0_g1,ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",ACSF3_HUMAN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,KEGG:hsa:197322`KO:K18660,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^100-513^E:1.1e-74,NA,NA,NA,NA,,
yes,AD,CSF,DN30330_c1_g1_i2,DN30330_c1_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^140-214^E:1.4e-11",NA,NA,NA,NA,,
yes,AD,CSF,DN30330_c1_g1_i1,DN30330_c1_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^134-208^E:1.3e-11",NA,NA,NA,NA,,
yes,AD,CSF,DN2885_c1_g1_i5,DN2885_c1_g1,CSF1R_FELCA,Macrophage colony-stimulating factor 1 receptor,.,NA,GO:0009986^cellular_component^cell surface,GO:1990682^cellular_component^CSF1-CSF1R complex,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:fca:493706`KO:K05090,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,AD,CSF,DN1940_c0_g1_i11,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",PF13360.6^PQQ_2^PQQ-like domain^111-210^E:9.6e-06,PF13570.6^PQQ_3^PQQ-like domain^129-166^E:9.7e-05,PF13570.6^PQQ_3^PQQ-like domain^171-209^E:1.7e-06,NA,NA,,
no,AD,CSF,DN1940_c0_g1_i3,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",.,NA,NA,NA,NA,,
no,AD,CSF,DN1940_c0_g1_i10,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",PF13360.6^PQQ_2^PQQ-like domain^68-233^E:4.7e-07,PF01011.21^PQQ^PQQ enzyme repeat^94-124^E:0.0002,PF13570.6^PQQ_3^PQQ-like domain^108-146^E:0.00035,PF13570.6^PQQ_3^PQQ-like domain^204-233^E:0.00012,NA,,
no,AD,CSF,DN1940_c0_g1_i5,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",.,NA,NA,NA,NA,,
no,AD,CSF,DN1940_c0_g1_i12,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",PF00501.28^AMP-binding^AMP-binding enzyme^11-457^E:7.3e-45,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^478-535^E:2.3e-05,PF13360.6^PQQ_2^PQQ-like domain^809-908^E:0.00013,PF13360.6^PQQ_2^PQQ-like domain^820-973^E:3.2e-08,PF13570.6^PQQ_3^PQQ-like domain^827-864^E:0.00084,,
no,AD,CSF,DN1940_c0_g1_i8,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^47-102^E:1.7e-05,NA,NA,NA,NA,,
no,AD,CSF,DN1940_c0_g1_i2,DN1940_c0_g1,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",PF13360.6^PQQ_2^PQQ-like domain^237-336^E:4.4e-05,PF13360.6^PQQ_2^PQQ-like domain^248-406^E:9.3e-09,PF13570.6^PQQ_3^PQQ-like domain^255-292^E:0.00036,PF13570.6^PQQ_3^PQQ-like domain^297-335^E:6.4e-06,PF13360.6^PQQ_2^PQQ-like domain^412-512^E:0.00014,,
no,AD,CSF,DN1940_c0_g2_i1,DN1940_c0_g2,ACSF4_MOUSE,Beta-alanine-activating enzyme {ECO:0000303|PubMed:24467666},.,NA,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:mmu:231326`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",.,NA,NA,NA,NA,,
no,AD,CSF,DN1940_c0_g3_i1,DN1940_c0_g3,ACSF4_HUMAN,Beta-alanine-activating enzyme {ECO:0000250|UniProtKB:Q80WC9},.,NA,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0043041^biological_process^amino acid activation for nonribosomal peptide biosynthetic process,GO:0019482^biological_process^beta-alanine metabolic process,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:hsa:132949`KO:K00142,"COG1520^Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)",.,NA,NA,NA,NA,,
no,AD,CSF,DN57633_c0_g1_i1,DN57633_c0_g1,ACSF2_DANRE,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,.,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
yes,AD,CSF,DN35220_c0_g1_i4,DN35220_c0_g1,CSF11_TAKRU,Macrophage colony-stimulating factor 1 receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0019955^molecular_function^cytokine binding,GO:0004714^molecular_function^transmembrane receptor protein tyrosine kinase activity,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,CSF,DN35220_c0_g1_i6,DN35220_c0_g1,CSF11_TAKRU,Macrophage colony-stimulating factor 1 receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0019955^molecular_function^cytokine binding,GO:0004714^molecular_function^transmembrane receptor protein tyrosine kinase activity,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,AD,CSF,DN85180_c0_g1_i2,DN85180_c0_g1,ACSF3_BOVIN,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000250|UniProtKB:Q4G176}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0016874^molecular_function^ligase activity,GO:0006631^biological_process^fatty acid metabolic process,NA,.,NA,NA,NA,NA,KEGG:bta:509209`KO:K18660,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CSF,DN6173_c0_g1_i2,DN6173_c0_g1,ACSF3_MOUSE,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,GO:0031957^molecular_function^very long-chain fatty acid-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:257633`KO:K18660,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CSF,DN6173_c0_g2_i1,DN6173_c0_g2,ACSF3_MOUSE,"Malonate--CoA ligase ACSF3, mitochondrial {ECO:0000305}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0016878^molecular_function^acid-thiol ligase activity,GO:0005524^molecular_function^ATP binding,GO:0090409^molecular_function^malonyl-CoA synthetase activity,GO:0031957^molecular_function^very long-chain fatty acid-CoA ligase activity,.,NA,NA,NA,NA,KEGG:mmu:257633`KO:K18660,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
yes,AD,CSF,DN1549_c1_g1_i1,DN1549_c1_g1,CSF1_MOUSE,Macrophage colony-stimulating factor 1,CSF1_MOUSE,Macrophage colony-stimulating factor 1,GO:1990682^cellular_component^CSF1-CSF1R complex,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:1990682^cellular_component^CSF1-CSF1R complex,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,KEGG:mmu:12977`KO:K05453,ENOG410Z5Q9^Colony stimulating factor 1 (Macrophage),PF05337.11^CSF-1^Macrophage colony stimulating factor-1 (CSF-1)^67-205^E:3.7e-17,NA,NA,NA,NA,,
yes,AD,CSF,DN1549_c1_g1_i2,DN1549_c1_g1,CSF1_MOUSE,Macrophage colony-stimulating factor 1,.,NA,GO:1990682^cellular_component^CSF1-CSF1R complex,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:mmu:12977`KO:K05453,ENOG410Z5Q9^Colony stimulating factor 1 (Macrophage),.,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i10,DN367_c0_g1,ACSF2_MACFA,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:pon:100172872`KO:K00666,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^80-324^E:2.1e-41,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i17,DN367_c0_g1,ACSF2_MOUSE,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000305}",ACSF2_MOUSE,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000305}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:mmu:264895`KO:K00666,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^2-196^E:2.3e-49,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^205-259^E:9.1e-09,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i15,DN367_c0_g1,ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:pon:100172872`KO:K00666,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i1,DN367_c0_g1,ACSF2_RAT,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000305}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:rno:619561`KO:K00666,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i12,DN367_c0_g1,ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:pon:100172872`KO:K00666,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i8,DN367_c0_g1,ACSF2_MACFA,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",ACSF2_RAT,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000305}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:rno:619561`KO:K00666,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^13-124^E:4.1e-35,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^133-208^E:3.3e-17,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i7,DN367_c0_g1,ACSF2_MACFA,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",ACSF2_MACFA,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:mcf:101864763`KO:K00666,.,PF00501.28^AMP-binding^AMP-binding enzyme^2-110^E:2e-34,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^119-201^E:4.2e-15,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i3,DN367_c0_g1,ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:pon:100172872`KO:K00666,COG0318^Amp-dependent synthetase and ligase,PF13193.6^AMP-binding_C^AMP-binding enzyme C-terminal domain^13-88^E:4.6e-18,NA,NA,NA,NA,,
no,AD,CSF,DN367_c0_g1_i13,DN367_c0_g1,ACSF2_MOUSE,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000305}",ACSF2_PONAB,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:pon:100172872`KO:K00666,COG0318^Amp-dependent synthetase and ligase,PF00501.28^AMP-binding^AMP-binding enzyme^80-324^E:2.1e-41,NA,NA,NA,NA,,
yes,AD,CSF,DN6295_c0_g1_i15,DN6295_c0_g1,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:hsa:1441`KO:K05061,ENOG410XVIU^Colony stimulating factor 3 receptor (Granulocyte),.,NA,NA,NA,NA,,
yes,AD,CSF,DN6295_c0_g1_i5,DN6295_c0_g1,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:hsa:1441`KO:K05061,ENOG410XVIU^Colony stimulating factor 3 receptor (Granulocyte),.,NA,NA,NA,NA,,
yes,AD,CSF,DN6295_c0_g1_i13,DN6295_c0_g1,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1441`KO:K05061,ENOG410XVIU^Colony stimulating factor 3 receptor (Granulocyte),.,NA,NA,NA,NA,,
yes,AD,CSF,DN6295_c0_g1_i14,DN6295_c0_g1,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,CSF3R_HUMAN,Granulocyte colony-stimulating factor receptor,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1441`KO:K05061,ENOG410XVIU^Colony stimulating factor 3 receptor (Granulocyte),.,NA,NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i2,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3.7e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^127-219^E:1.5e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i10,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3.1e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^133-225^E:1.2e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i3,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^127-219^E:1.2e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i6,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3.5e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^127-219^E:1.4e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i7,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^133-225^E:1.2e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i4,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^127-219^E:1.2e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i8,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^9-101^E:4.9e-18",NA,NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g1_i5,DN5342_c0_g1,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^41-110^E:3.7e-11,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^133-225^E:1.5e-17",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g2_i3,DN5342_c0_g2,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g2_i2,DN5342_c0_g2,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g2_i1,DN5342_c0_g2,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^36-102^E:2.7e-10,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^124-215^E:6.6e-22",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g2_i4,DN5342_c0_g2,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:1438`KO:K05066,.,PF18611.1^IL3Ra_N^IL-3 receptor alpha chain N-terminal domain^36-102^E:2.7e-10,"PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^124-215^E:6.6e-22",NA,NA,NA,,
yes,AD,CSF,DN5342_c0_g3_i1,DN5342_c0_g3,CSF2R_HUMAN,Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:hsa:1438`KO:K05066,.,.,NA,NA,NA,NA,,
yes,AD,CSF,DN117332_c0_g1_i1,DN117332_c0_g1,CSF11_TAKRU,Macrophage colony-stimulating factor 1 receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0019955^molecular_function^cytokine binding,GO:0004714^molecular_function^transmembrane receptor protein tyrosine kinase activity,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,AD,CSF,DN354364_c0_g1_i1,DN354364_c0_g1,ACSF2_BOVIN,"Medium-chain acyl-CoA ligase ACSF2, mitochondrial {ECO:0000250|UniProtKB:Q96CM8}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0047760^molecular_function^butyrate-CoA ligase activity,GO:0031956^molecular_function^medium-chain fatty acid-CoA ligase activity,GO:0006631^biological_process^fatty acid metabolic process,.,NA,NA,NA,NA,KEGG:bta:768237`KO:K00666,COG0318^Amp-dependent synthetase and ligase,.,NA,NA,NA,NA,,
no,AD,CX3,DN40917_c0_g1_i2,DN40917_c0_g1,OCX32_CHICK,Ovocalyxin-32,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,.,NA,NA,NA,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,.,NA,NA,NA,NA,,
yes,AD,CX3,DN10428_c0_g1_i2,DN10428_c0_g1,CX3C1_HUMAN,CX3C chemokine receptor 1,CX3C1_HUMAN,CX3C chemokine receptor 1,GO:0009986^cellular_component^cell surface,GO:0097447^cellular_component^dendritic tree,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043005^cellular_component^neuron projection,GO:0009986^cellular_component^cell surface,GO:0097447^cellular_component^dendritic tree,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043005^cellular_component^neuron projection,KEGG:hsa:1524`KO:K04192,ENOG41118PP^Chemokine (C-X3-C motif) receptor 1,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^72-317^E:7.6e-52,NA,NA,NA,NA,,
yes,AD,CX3,DN10428_c0_g1_i1,DN10428_c0_g1,CX3C1_HUMAN,CX3C chemokine receptor 1,CX3C1_HUMAN,CX3C chemokine receptor 1,GO:0009986^cellular_component^cell surface,GO:0097447^cellular_component^dendritic tree,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043005^cellular_component^neuron projection,GO:0009986^cellular_component^cell surface,GO:0097447^cellular_component^dendritic tree,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043005^cellular_component^neuron projection,KEGG:hsa:1524`KO:K04192,ENOG41118PP^Chemokine (C-X3-C motif) receptor 1,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^70-315^E:7.5e-52,NA,NA,NA,NA,,
no,AD,CX3,DN11465_c1_g1_i1,DN11465_c1_g1,PLCX3_HUMAN,PI-PLC X domain-containing protein 3,PLCX3_BOVIN,PI-PLC X domain-containing protein 3,GO:0005737^cellular_component^cytoplasm,GO:0008081^molecular_function^phosphoric diester hydrolase activity,GO:0016042^biological_process^lipid catabolic process,GO:0007165^biological_process^signal transduction,NA,GO:0008081^molecular_function^phosphoric diester hydrolase activity,GO:0016042^biological_process^lipid catabolic process,GO:0007165^biological_process^signal transduction,NA,NA,KEGG:bta:781239,ENOG410Z30Q^Phosphatidylinositol-specific phospholipase C X domain containing,.,NA,NA,NA,NA,,
no,AD,CX3,DN15305_c0_g1_i8,DN15305_c0_g1,.,NA,PCX3_HUMAN,Pecanex-like protein 3,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:399909,ENOG410XPRI^-Drosophila,.,NA,NA,NA,NA,,
no,AD,CX3,DN15305_c0_g1_i4,DN15305_c0_g1,.,NA,PCX3_HUMAN,Pecanex-like protein 3,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:399909,ENOG410XPRI^-Drosophila,.,NA,NA,NA,NA,,
no,AD,CX3,DN15305_c0_g1_i6,DN15305_c0_g1,.,NA,PCX3_HUMAN,Pecanex-like protein 3,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:399909,ENOG410XPRI^-Drosophila,.,NA,NA,NA,NA,,
no,AD,CX3,DN15305_c0_g1_i2,DN15305_c0_g1,.,NA,PCX3_HUMAN,Pecanex-like protein 3,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:hsa:399909,ENOG410XPRI^-Drosophila,.,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i8,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^2-173^E:8.4e-72,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i6,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^2-123^E:3.8e-42,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i9,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^2-123^E:3.8e-42,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i2,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^40-206^E:3.5e-56,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i12,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^2-173^E:8.4e-72,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i7,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^40-206^E:3.5e-56,NA,NA,NA,NA,,
no,AD,CX3,DN1615_c0_g1_i10,DN1615_c0_g1,OCX32_CHICK,Ovocalyxin-32,OCX32_CHICK,Ovocalyxin-32,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0008191^molecular_function^metalloendopeptidase inhibitor activity,GO:0031214^biological_process^biomineral tissue development,NA,KEGG:gga:395209,ENOG4111K9R^retinoic acid receptor responder (tazarotene induced) 1,PF06907.12^Latexin^Latexin^2-127^E:1.6e-43,NA,NA,NA,NA,,
yes,AD,CXCR4,DN10639_c0_g1_i1,DN10639_c0_g1,CXCR4_PAPAN,C-X-C chemokine receptor type 4,CXCR4_PANTR,C-X-C chemokine receptor type 4,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,KEGG:ptr:450130`KO:K04189,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^3-240^E:8.7e-47,NA,NA,NA,NA,,
yes,AD,CXCR4,DN10639_c0_g1_i3,DN10639_c0_g1,CXCR4_PAPAN,C-X-C chemokine receptor type 4,CXCR4_PANTR,C-X-C chemokine receptor type 4,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,KEGG:ptr:450130`KO:K04189,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^3-240^E:8.7e-47,NA,NA,NA,NA,,
yes,AD,CXCR4,DN10639_c0_g1_i2,DN10639_c0_g1,CXCR4_PANTR,C-X-C chemokine receptor type 4,CXCR4_PAPAN,C-X-C chemokine receptor type 4,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,GO:0030054^cellular_component^cell junction,GO:0005769^cellular_component^early endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,KEGG:ptr:450130`KO:K04189,ENOG410XRW9^Receptor,PF12109.8^CXCR4_N^CXCR4 Chemokine receptor N terminal^38-70^E:3.6e-19,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^87-334^E:2.9e-50,NA,NA,NA,,
no,AD,DB,DN28759_c2_g1_i1,DN28759_c2_g1,DCA10_XENLA,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xla:379080`KO:K11802,.,.,NA,NA,NA,NA,,
no,AD,DB,DN12412_c0_g1_i7,DN12412_c0_g1,CL2DB_RAT,C-type lectin domain family 2 member D11,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,.,NA,NA,NA,NA,KEGG:rno:362447,ENOG410XPJ1^c-type lectin domain family,.,NA,NA,NA,NA,,
no,AD,DB,DN4704_c2_g1_i2,DN4704_c2_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,.,NA,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN87617_c0_g1_i2,DN87617_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN87642_c0_g1_i1,DN87642_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN20644_c0_g1_i2,DN20644_c0_g1,ATOH8_DANRE,Protein atonal homolog 8 {ECO:0000312|ZFIN:ZDB-GENE-061215-7},ATOH8_DANRE,Protein atonal homolog 8 {ECO:0000312|ZFIN:ZDB-GENE-061215-7},GO:0005737^cellular_component^cytoplasm,GO:0016607^cellular_component^nuclear speck,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046983^molecular_function^protein dimerization activity,GO:0005737^cellular_component^cytoplasm,GO:0016607^cellular_component^nuclear speck,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0046983^molecular_function^protein dimerization activity,KEGG:dre:561606`KO:K09084,ENOG4111WSZ^Atonal homolog 8 (Drosophila),PF00010.26^HLH^Helix-loop-helix DNA-binding domain^124-175^E:5.8e-15,NA,NA,NA,NA,,
no,AD,DB,DN3878_c0_g1_i6,DN3878_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^76-208^E:1e-07,NA,NA,NA,NA,,
no,AD,DB,DN3878_c0_g1_i2,DN3878_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN3878_c0_g1_i4,DN3878_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF07653.17^SH3_2^Variant SH3 domain^10-59^E:9.1e-07,PF00018.28^SH3_1^SH3 domain^12-56^E:1e-06,NA,NA,NA,,
no,AD,DB,DN3878_c0_g1_i5,DN3878_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN11635_c0_g1_i5,DN11635_c0_g1,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN11635_c0_g1_i1,DN11635_c0_g1,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN11635_c0_g1_i2,DN11635_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i2,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^149-280^E:2.9e-54,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i11,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,.,NA,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i7,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^1-78^E:8.9e-34,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i4,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^1-78^E:8.9e-34,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i5,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^82-162^E:7e-31,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i8,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i1,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^82-162^E:7e-31,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g1_i12,DN2961_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,ZN326_CHICK,DBIRD complex subunit ZNF326,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,PF04988.12^AKAP95^A-kinase anchoring protein 95 (AKAP95)^1-78^E:8.9e-34,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g2_i1,DN2961_c0_g2,ZN326_CHICK,DBIRD complex subunit ZNF326,.,NA,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN2961_c0_g3_i1,DN2961_c0_g3,ZN326_CHICK,DBIRD complex subunit ZNF326,.,NA,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN53285_c0_g1_i1,DN53285_c0_g1,PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,.,NA,NA,NA,NA,KEGG:ptr:462130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN53271_c0_g1_i1,DN53271_c0_g1,DDB1_RAT,DNA damage-binding protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,.,ENOG410XPF6^DNA- binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN53271_c0_g1_i2,DN53271_c0_g1,DDB1_RAT,DNA damage-binding protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,.,ENOG410XPF6^DNA- binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN44127_c0_g1_i1,DN44127_c0_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},.,NA,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,.,NA,NA,NA,NA,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i4,DN9662_c0_g1,TADBP_HUMAN,TAR DNA-binding protein 43,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:23435,ENOG410ZYQJ^TAR DNA binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i5,DN9662_c0_g1,TADBP_CHICK,TAR DNA-binding protein 43,TADBP_CHICK,TAR DNA-binding protein 43,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,KEGG:gga:419453,ENOG410ZYQJ^TAR DNA binding protein,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^1-40^E:5.3e-07",NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i2,DN9662_c0_g1,TADBP_CHICK,TAR DNA-binding protein 43,TADBP_CHICK,TAR DNA-binding protein 43,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,KEGG:gga:419453,ENOG410ZYQJ^TAR DNA binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i17,DN9662_c0_g1,TADBP_HUMAN,TAR DNA-binding protein 43,TADBP_HUMAN,TAR DNA-binding protein 43,GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:23435,ENOG410ZYQJ^TAR DNA binding protein,PF18694.1^TDP43_N^Transactive response DNA-binding protein N-terminal domain^4-76^E:6.9e-34,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^106-137^E:1.4e-05",NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i15,DN9662_c0_g1,TADBP_CHICK,TAR DNA-binding protein 43,TADBP_CHICK,TAR DNA-binding protein 43,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,KEGG:gga:419453,ENOG410ZYQJ^TAR DNA binding protein,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^12-60^E:2.1e-09",NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i10,DN9662_c0_g1,TADBP_CHICK,TAR DNA-binding protein 43,MASP2_HUMAN,Mannan-binding lectin serine protease 2,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003690^molecular_function^double-stranded DNA binding,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0048306^molecular_function^calcium-dependent protein binding,KEGG:hsa:10747`KO:K03993,COG5640^protease,PF00089.26^Trypsin^Trypsin^25-85^E:2.4e-12,NA,NA,NA,NA,,
no,AD,DB,DN9662_c0_g1_i13,DN9662_c0_g1,TADBP_HUMAN,TAR DNA-binding protein 43,TADBP_HUMAN,TAR DNA-binding protein 43,GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:23435,ENOG410ZYQJ^TAR DNA binding protein,PF18694.1^TDP43_N^Transactive response DNA-binding protein N-terminal domain^4-76^E:6.9e-34,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^106-137^E:1.4e-05",NA,NA,NA,,
no,AD,DB,DN9644_c0_g1_i5,DN9644_c0_g1,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:hsa:8816`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,"PF00400.32^WD40^WD domain, G-beta repeat^54-86^E:0.00085","PF00400.32^WD40^WD domain, G-beta repeat^144-176^E:0.0053","PF00400.32^WD40^WD domain, G-beta repeat^333-366^E:0.009",NA,NA,,
no,AD,DB,DN9644_c0_g1_i4,DN9644_c0_g1,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:hsa:8816`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,"PF00400.32^WD40^WD domain, G-beta repeat^54-86^E:0.0003","PF00400.32^WD40^WD domain, G-beta repeat^144-176^E:0.0019",NA,NA,NA,,
no,AD,DB,DN9644_c0_g2_i1,DN9644_c0_g2,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:8816`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,.,NA,NA,NA,NA,,
no,AD,DB,DN52409_c0_g1_i1,DN52409_c0_g1,DCAF8_PONAB,DDB1- and CUL4-associated factor 8,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:pon:100174058`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN8781_c1_g1_i2,DN8781_c1_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN2034_c0_g1_i18,DN2034_c0_g1,TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,KEGG:dre:437021,ENOG4111IRY^tetraspanin,PF00335.20^Tetraspanin^Tetraspanin family^9-232^E:1.2e-43,NA,NA,NA,NA,,
no,AD,DB,DN2034_c0_g1_i8,DN2034_c0_g1,TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,KEGG:dre:437021,ENOG4111IRY^tetraspanin,PF00335.20^Tetraspanin^Tetraspanin family^16-187^E:6.6e-38,NA,NA,NA,NA,,
no,AD,DB,DN2034_c0_g1_i1,DN2034_c0_g1,TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,.,NA,NA,NA,NA,KEGG:dre:437021,ENOG4111IRY^tetraspanin,.,NA,NA,NA,NA,,
no,AD,DB,DN2034_c0_g1_i14,DN2034_c0_g1,TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,KEGG:dre:437021,ENOG4111IRY^tetraspanin,PF00335.20^Tetraspanin^Tetraspanin family^16-199^E:7.7e-41,NA,NA,NA,NA,,
no,AD,DB,DN2034_c0_g1_i3,DN2034_c0_g1,TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},TSN36_DANRE,Tetraspanin-36 {ECO:0000312|ZFIN:ZDB-GENE-040718-248},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0007275^biological_process^multicellular organism development,GO:0043473^biological_process^pigmentation,KEGG:dre:437021,ENOG4111IRY^tetraspanin,PF00335.20^Tetraspanin^Tetraspanin family^16-187^E:6.6e-38,NA,NA,NA,NA,,
no,AD,DB,DN2030_c0_g1_i1,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_CRIGR,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,GO:0007049^biological_process^cell cycle,GO:0006260^biological_process^DNA replication,KEGG:cge:100689339`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN2030_c0_g1_i5,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN2030_c0_g1_i6,DN2030_c0_g1,DBF4A_CRIGR,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,GO:0007049^biological_process^cell cycle,GO:0006260^biological_process^DNA replication,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN2030_c0_g1_i2,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN2030_c0_g1_i7,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),PF07535.12^zf-DBF^DBF zinc finger^292-334^E:1.5e-16,NA,NA,NA,NA,,
no,MJ,DB,DN2030_c0_g1_i13,DN2030_c0_g1,DBF4A_CRIGR,Protein DBF4 homolog A,DBF4A_CRIGR,Protein DBF4 homolog A,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,GO:0007049^biological_process^cell cycle,GO:0006260^biological_process^DNA replication,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,GO:0007049^biological_process^cell cycle,GO:0006260^biological_process^DNA replication,KEGG:cge:100689339`KO:K06629,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN2030_c0_g1_i14,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,MJ,DB,DN2030_c0_g1_i8,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_CRIGR,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0005634^cellular_component^nucleus,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,GO:0007049^biological_process^cell cycle,GO:0006260^biological_process^DNA replication,KEGG:cge:100689339`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,MJ,DB,DN2030_c0_g1_i3,DN2030_c0_g1,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,MJ,DB,DN2030_c0_g2_i1,DN2030_c0_g2,DBF4A_HUMAN,Protein DBF4 homolog A,DBF4A_HUMAN,Protein DBF4 homolog A,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008047^molecular_function^enzyme activator activity,KEGG:hsa:10926`KO:K06629,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,MJ,DB,DN409_c0_g1_i2,DN409_c0_g1,ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,KEGG:bta:280759`KO:K09699,COG0508^Dehydrogenase,PF00364.22^Biotin_lipoyl^Biotin-requiring enzyme^220-292^E:2.9e-18,PF02817.17^E3_binding^e3 binding domain^328-362^E:1.2e-14,PF00198.23^2-oxoacid_dh^2-oxoacid dehydrogenases acyltransferase (catalytic domain)^415-644^E:8.2e-79,NA,NA,,
no,MJ,DB,DN409_c0_g1_i3,DN409_c0_g1,ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,KEGG:bta:280759`KO:K09699,COG0508^Dehydrogenase,PF02817.17^E3_binding^e3 binding domain^17-51^E:5.4e-15,PF00198.23^2-oxoacid_dh^2-oxoacid dehydrogenases acyltransferase (catalytic domain)^104-333^E:1.6e-79,NA,NA,NA,,
no,MJ,DB,DN409_c0_g1_i6,DN409_c0_g1,ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,KEGG:bta:280759`KO:K09699,COG0508^Dehydrogenase,PF00364.22^Biotin_lipoyl^Biotin-requiring enzyme^101-173^E:2.2e-18,PF02817.17^E3_binding^e3 binding domain^209-243^E:9.6e-15,PF00198.23^2-oxoacid_dh^2-oxoacid dehydrogenases acyltransferase (catalytic domain)^296-525^E:5.2e-79,NA,NA,,
no,MJ,DB,DN409_c0_g1_i4,DN409_c0_g1,ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,.,NA,NA,NA,NA,KEGG:bta:280759`KO:K09699,COG0508^Dehydrogenase,.,NA,NA,NA,NA,,
no,MJ,DB,DN409_c0_g1_i5,DN409_c0_g1,ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",ODB2_BOVIN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,KEGG:bta:280759`KO:K09699,COG0508^Dehydrogenase,PF02817.17^E3_binding^e3 binding domain^17-51^E:5.4e-15,PF00198.23^2-oxoacid_dh^2-oxoacid dehydrogenases acyltransferase (catalytic domain)^104-333^E:1.6e-79,NA,NA,NA,,
no,MJ,DB,DN43427_c0_g1_i1,DN43427_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,MJ,DB,DN17109_c0_g1_i3,DN17109_c0_g1,PCDBD_PANTR,Protocadherin beta-13,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,MJ,DB,DN17109_c0_g1_i2,DN17109_c0_g1,PCDBD_PANTR,Protocadherin beta-13,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i13,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,TGM7_HUMAN,Protein-glutamine gamma-glutamyltransferase Z,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,GO:0046872^molecular_function^metal ion binding,GO:0003810^molecular_function^protein-glutamine gamma-glutamyltransferase activity,GO:0018149^biological_process^peptide cross-linking,NA,NA,KEGG:hsa:116179`KO:K05623,ENOG410XQEZ^transglutaminase,PF01841.19^Transglut_core^Transglutaminase-like superfamily^28-58^E:5.1e-07,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i6,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,KEGG:xla:495493`KO:K21626,.,PF13324.6^GCIP^Grap2 and cyclin-D-interacting^5-118^E:8.8e-35,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i14,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,.,NA,NA,NA,NA,KEGG:xla:495493`KO:K21626,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i7,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,.,NA,NA,NA,NA,KEGG:xla:495493`KO:K21626,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i5,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,KEGG:xla:495493`KO:K21626,.,PF13324.6^GCIP^Grap2 and cyclin-D-interacting^25-269^E:2.3e-84,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i3,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,.,NA,NA,NA,NA,KEGG:xla:495493`KO:K21626,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i17,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,.,NA,NA,NA,NA,KEGG:xla:495493`KO:K21626,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i16,DN6970_c0_g1,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,KEGG:xla:495493`KO:K21626,.,PF13324.6^GCIP^Grap2 and cyclin-D-interacting^6-110^E:2.9e-31,NA,NA,NA,NA,,
no,MJ,DB,DN6970_c0_g1_i19,DN6970_c0_g1,.,NA,CCDB1_XENLA,Cyclin-D1-binding protein 1 homolog,.,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0051726^biological_process^regulation of cell cycle,NA,KEGG:xla:495493`KO:K21626,.,.,NA,NA,NA,NA,,
no,MJ,DB,DN6928_c0_g1_i5,DN6928_c0_g1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,.,ENOG4110DBH^regulation of mitochondrial membrane permeability involved in apoptotic process,.,NA,NA,NA,NA,,
no,MJ,DB,DN6928_c0_g1_i2,DN6928_c0_g1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,.,ENOG4110DBH^regulation of mitochondrial membrane permeability involved in apoptotic process,.,NA,NA,NA,NA,,
no,MJ,DB,DN6928_c0_g1_i13,DN6928_c0_g1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,.,ENOG4110DBH^regulation of mitochondrial membrane permeability involved in apoptotic process,.,NA,NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i2,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,"PF05011.13^DBR1^Lariat debranching enzyme, C-terminal domain^181-312^E:2.2e-35",NA,NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i4,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,PF00149.28^Metallophos^Calcineurin-like phosphoesterase^9-163^E:0.00041,"PF05011.13^DBR1^Lariat debranching enzyme, C-terminal domain^181-243^E:2.7e-20",NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i7,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,"PF05011.13^DBR1^Lariat debranching enzyme, C-terminal domain^5-69^E:6.7e-10",NA,NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i1,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,"PF05011.13^DBR1^Lariat debranching enzyme, C-terminal domain^15-128^E:1e-21",NA,NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i8,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,"PF05011.13^DBR1^Lariat debranching enzyme, C-terminal domain^15-128^E:1e-21",NA,NA,NA,NA,,
no,AD,DB,DN6993_c0_g1_i9,DN6993_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,PF00149.28^Metallophos^Calcineurin-like phosphoesterase^1-229^E:8.9e-12,NA,NA,NA,NA,,
no,AD,DB,DN25313_c0_g1_i1,DN25313_c0_g1,LDB1_HUMAN,LIM domain-binding protein 1,.,NA,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0031252^cellular_component^cell leading edge,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:8861`KO:K15617,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN42546_c0_g2_i1,DN42546_c0_g2,SVKA_DICDI,Serine/threonine-protein kinase svkA,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0032154^cellular_component^cleavage furrow,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0286359`KO:K08838,ENOG410XP9G^mitogen-activated protein kinase kinase kinase kinase,.,NA,NA,NA,NA,,
no,AD,DB,DN16384_c0_g1_i2,DN16384_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN16384_c0_g1_i1,DN16384_c0_g1,DCAF6_PONAB,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172900`KO:K11795,.,.,NA,NA,NA,NA,,
no,AD,DB,DN49975_c0_g1_i2,DN49975_c0_g1,DDB1_MOUSE,DNA damage-binding protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:13194`KO:K10610,ENOG410XPF6^DNA- binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN15596_c1_g1_i1,DN15596_c1_g1,ADB4C_MELGA,Beta-4C adrenergic receptor,ADB4C_MELGA,Beta-4C adrenergic receptor,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004940^molecular_function^beta1-adrenergic receptor activity,GO:0007189^biological_process^adenylate cyclase-activating G protein-coupled receptor signaling pathway,GO:0045823^biological_process^positive regulation of heart contraction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004940^molecular_function^beta1-adrenergic receptor activity,GO:0007189^biological_process^adenylate cyclase-activating G protein-coupled receptor signaling pathway,GO:0045823^biological_process^positive regulation of heart contraction,KEGG:mgp:100379211`KO:K04143,ENOG410XRW9^Receptor,PF13853.6^7tm_4^Olfactory receptor^42-225^E:5e-07,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^46-290^E:1.7e-08,PF10328.9^7TM_GPCR_Srx^Serpentine type 7TM GPCR chemoreceptor Srx^46-230^E:6.2e-08,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^50-293^E:1.5e-65,PF10323.9^7TM_GPCR_Srv^Serpentine type 7TM GPCR chemoreceptor Srv^123-222^E:0.00011,,
no,AD,DB,DN15591_c0_g1_i11,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2_HUMAN,Proto-oncogene DBL,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^101-216^E:5.7e-07,PF00621.20^RhoGEF^RhoGEF domain^641-815^E:2.5e-39,PF00169.29^PH^PH domain^837-950^E:4.2e-06,PF00018.28^SH3_1^SH3 domain^1059-1106^E:2e-06,NA,,
no,AD,DB,DN15591_c0_g1_i5,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2_HUMAN,Proto-oncogene DBL,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^101-216^E:5.4e-07,PF00621.20^RhoGEF^RhoGEF domain^641-815^E:2.3e-39,PF00169.29^PH^PH domain^837-950^E:4e-06,NA,NA,,
no,AD,DB,DN15591_c0_g1_i9,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2_HUMAN,Proto-oncogene DBL,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^23-138^E:2.4e-07,PF00621.20^RhoGEF^RhoGEF domain^563-621^E:6.9e-08,NA,NA,NA,,
no,AD,DB,DN15591_c0_g1_i1,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2_HUMAN,Proto-oncogene DBL,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^23-138^E:4.1e-07,PF00621.20^RhoGEF^RhoGEF domain^563-737^E:1.7e-39,PF00169.29^PH^PH domain^759-872^E:3.1e-06,NA,NA,,
no,AD,DB,DN15591_c0_g1_i12,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,.,NA,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,.,NA,NA,NA,NA,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,.,NA,NA,NA,NA,,
no,AD,DB,DN15591_c0_g1_i6,DN15591_c0_g1,MCF2L_RAT,Guanine nucleotide exchange factor DBS,MCF2L_RAT,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0019898^cellular_component^extrinsic component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008289^molecular_function^lipid binding,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0019898^cellular_component^extrinsic component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008289^molecular_function^lipid binding,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,.,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF00621.20^RhoGEF^RhoGEF domain^2-87^E:6.4e-19,PF00169.29^PH^PH domain^109-222^E:8.7e-07,PF07653.17^SH3_2^Variant SH3 domain^329-383^E:6.2e-05,PF00018.28^SH3_1^SH3 domain^331-378^E:5.4e-07,NA,,
no,AD,DB,DN15591_c0_g1_i4,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2L_RAT,Guanine nucleotide exchange factor DBS,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005737^cellular_component^cytoplasm,GO:0019898^cellular_component^extrinsic component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008289^molecular_function^lipid binding,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,KEGG:hsa:4168`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF07653.17^SH3_2^Variant SH3 domain^38-92^E:6.4e-06,PF00018.28^SH3_1^SH3 domain^40-87^E:6.3e-08,NA,NA,NA,,
no,AD,DB,DN15591_c0_g1_i10,DN15591_c0_g1,MCF2_HUMAN,Proto-oncogene DBL,MCF2_HUMAN,Proto-oncogene DBL,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,GO:1990830^biological_process^cellular response to leukemia inhibitory factor,KEGG:hsa:4168`KO:K20685,ENOG410XPCA^mcf.2 cell line derived transforming,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^101-216^E:5.6e-07,PF00621.20^RhoGEF^RhoGEF domain^641-815^E:2.5e-39,PF00169.29^PH^PH domain^837-950^E:4.2e-06,PF00018.28^SH3_1^SH3 domain^1059-1106^E:2e-06,NA,,
no,AD,DB,DN840_c0_g2_i1,DN840_c0_g2,RBM38_CHICK,RNA-binding protein 38,RBM38_CHICK,RNA-binding protein 38,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0003729^molecular_function^mRNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0003729^molecular_function^mRNA binding,KEGG:gga:768866,ENOG410YDBV^NA,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^13-70^E:9.9e-18",NA,NA,NA,NA,,
no,AD,DB,DN5170_c0_g1_i11,DN5170_c0_g1,RAC1C_DICDI,Rho-related protein rac1C,RAC1C_DICDI,Rho-related protein rac1C,GO:0005938^cellular_component^cell cortex,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005525^molecular_function^GTP binding,GO:0005938^cellular_component^cell cortex,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005525^molecular_function^GTP binding,KEGG:ddi:DDB_G0282365`KO:K04392,COG1100^GTP-binding Protein,PF00071.22^Ras^Ras family^5-75^E:4e-27,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^5-72^E:2.9e-13",NA,NA,NA,,
no,AD,DB,DN5170_c0_g1_i2,DN5170_c0_g1,RAC1_RAT,Ras-related C3 botulinum toxin substrate 1 {ECO:0000305},RAC1C_DICDI,Rho-related protein rac1C,GO:0005884^cellular_component^actin filament,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005938^cellular_component^cell cortex,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005525^molecular_function^GTP binding,KEGG:ddi:DDB_G0282365`KO:K04392,COG1100^GTP-binding Protein,PF00071.22^Ras^Ras family^5-75^E:4e-27,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^5-72^E:2.9e-13",NA,NA,NA,,
no,AD,DB,DN74348_c0_g1_i2,DN74348_c0_g1,GACHH_DICDI,Rho GTPase-activating protein gacHH,GACHH_DICDI,Rho GTPase-activating protein gacHH,GO:0005737^cellular_component^cytoplasm,GO:0005096^molecular_function^GTPase activator activity,GO:0007165^biological_process^signal transduction,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0005096^molecular_function^GTPase activator activity,GO:0007165^biological_process^signal transduction,NA,NA,KEGG:ddi:DDB_G0272080,ENOG410XPZ9^Rho GTPase activating protein 29,"PF13418.6^Kelch_4^Galactose oxidase, central domain^18-58^E:7.7e-07",PF01344.25^Kelch_1^Kelch motif^29-59^E:5.1e-05,"PF13415.6^Kelch_3^Galactose oxidase, central domain^78-131^E:1e-05",PF13854.6^Kelch_5^Kelch motif^121-156^E:2.5e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^123-156^E:1e-05",,
no,AD,DB,DN4262_c1_g1_i1,DN4262_c1_g1,FORI_DICDI,Formin-I,FORI_DICDI,Formin-I,GO:0003779^molecular_function^actin binding,GO:0005522^molecular_function^profilin binding,NA,NA,NA,GO:0003779^molecular_function^actin binding,GO:0005522^molecular_function^profilin binding,NA,NA,NA,KEGG:ddi:DDB_G0284519,.,PF02181.23^FH2^Formin Homology 2 Domain^369-645^E:7.9e-58,NA,NA,NA,NA,,
no,AD,DB,DN4262_c1_g1_i7,DN4262_c1_g1,FORH_DICDI,Formin-H,FORH_DICDI,Formin-H,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,KEGG:ddi:DDB_G0285589,ENOG410Y3DT^formin-like,PF02181.23^FH2^Formin Homology 2 Domain^348-707^E:3.9e-68,NA,NA,NA,NA,,
no,AD,DB,DN4262_c1_g1_i3,DN4262_c1_g1,FORH_DICDI,Formin-H,FORH_DICDI,Formin-H,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,KEGG:ddi:DDB_G0285589,ENOG410Y3DT^formin-like,PF02181.23^FH2^Formin Homology 2 Domain^348-707^E:3.9e-68,NA,NA,NA,NA,,
no,AD,DB,DN4262_c1_g1_i2,DN4262_c1_g1,FORI_DICDI,Formin-I,.,NA,GO:0003779^molecular_function^actin binding,GO:0005522^molecular_function^profilin binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0284519,.,.,NA,NA,NA,NA,,
no,AD,DB,DN4262_c1_g1_i4,DN4262_c1_g1,FORH_DICDI,Formin-H,FORH_DICDI,Formin-H,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,GO:0015629^cellular_component^actin cytoskeleton,GO:0005938^cellular_component^cell cortex,GO:0031254^cellular_component^cell trailing edge,GO:0030175^cellular_component^filopodium,GO:0032433^cellular_component^filopodium tip,KEGG:ddi:DDB_G0285589,ENOG410Y3DT^formin-like,PF02181.23^FH2^Formin Homology 2 Domain^369-728^E:4.2e-68,NA,NA,NA,NA,,
no,AD,DB,DN4270_c0_g1_i7,DN4270_c0_g1,AMDB_XENLA,Peptidyl-glycine alpha-amidating monooxygenase B,AMDB_XENLA,Peptidyl-glycine alpha-amidating monooxygenase B,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,KEGG:xla:397736`KO:K00504`KO:K18200,.,"PF01082.20^Cu2_monooxygen^Copper type II ascorbate-dependent monooxygenase, N-terminal domain^61-172^E:7.2e-25","PF03712.15^Cu2_monoox_C^Copper type II ascorbate-dependent monooxygenase, C-terminal domain^198-342^E:3.9e-44",PF01436.21^NHL^NHL repeat^523-552^E:2.3e-05,NA,NA,,
no,AD,DB,DN4270_c0_g1_i8,DN4270_c0_g1,AMDA_XENLA,Peptidyl-glycine alpha-amidating monooxygenase A,AMDB_XENLA,Peptidyl-glycine alpha-amidating monooxygenase B,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,KEGG:xla:397736`KO:K00504`KO:K18200,.,"PF01082.20^Cu2_monooxygen^Copper type II ascorbate-dependent monooxygenase, N-terminal domain^61-172^E:5.6e-25","PF03712.15^Cu2_monoox_C^Copper type II ascorbate-dependent monooxygenase, C-terminal domain^198-342^E:3e-44",PF01436.21^NHL^NHL repeat^523-552^E:1.9e-05,NA,NA,,
no,AD,DB,DN4270_c0_g1_i2,DN4270_c0_g1,AMDB_XENLA,Peptidyl-glycine alpha-amidating monooxygenase B,AMDB_XENLA,Peptidyl-glycine alpha-amidating monooxygenase B,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,GO:0016021^cellular_component^integral component of membrane,GO:0030658^cellular_component^transport vesicle membrane,GO:0005507^molecular_function^copper ion binding,GO:0004598^molecular_function^peptidylamidoglycolate lyase activity,GO:0004504^molecular_function^peptidylglycine monooxygenase activity,KEGG:xla:397736`KO:K00504`KO:K18200,.,"PF01082.20^Cu2_monooxygen^Copper type II ascorbate-dependent monooxygenase, N-terminal domain^61-172^E:7.4e-25","PF03712.15^Cu2_monoox_C^Copper type II ascorbate-dependent monooxygenase, C-terminal domain^198-342^E:4.1e-44",PF01436.21^NHL^NHL repeat^523-552^E:2.4e-05,NA,NA,,
no,AD,DB,DN89894_c0_g1_i1,DN89894_c0_g1,GFRP_HUMAN,GTP cyclohydrolase 1 feedback regulatory protein,GFRP_HUMAN,GTP cyclohydrolase 1 feedback regulatory protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:2644,ENOG4111X10^GTP cyclohydrolase I feedback regulator,PF06399.13^GFRP^GTP cyclohydrolase I feedback regulatory protein (GFRP)^31-113^E:3.9e-42,NA,NA,NA,NA,,
no,AD,DB,DN89894_c0_g1_i5,DN89894_c0_g1,GFRP_HUMAN,GTP cyclohydrolase 1 feedback regulatory protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:hsa:2644,ENOG4111X10^GTP cyclohydrolase I feedback regulator,.,NA,NA,NA,NA,,
no,AD,DB,DN89894_c0_g1_i4,DN89894_c0_g1,GFRP_BOVIN,GTP cyclohydrolase 1 feedback regulatory protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:bta:617650,ENOG4111X10^GTP cyclohydrolase I feedback regulator,.,NA,NA,NA,NA,,
no,AD,DB,DN89894_c0_g1_i6,DN89894_c0_g1,GFRP_HUMAN,GTP cyclohydrolase 1 feedback regulatory protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:hsa:2644,ENOG4111X10^GTP cyclohydrolase I feedback regulator,.,NA,NA,NA,NA,,
no,AD,DB,DN13972_c0_g1_i2,DN13972_c0_g1,ARL8_DICDI,ADP-ribosylation factor-like protein 8,.,NA,GO:0005765^cellular_component^lysosomal membrane,GO:0005774^cellular_component^vacuolar membrane,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0283525`KO:K07955,ENOG410XNUK^ADP-ribosylation factor-like,.,NA,NA,NA,NA,,
no,AD,DB,DN8234_c0_g1_i5,DN8234_c0_g1,SSBP2_HUMAN,Single-stranded DNA-binding protein 2,SSBP2_HUMAN,Single-stranded DNA-binding protein 2,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,KEGG:hsa:23635,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^1-117^E:1e-33",NA,NA,NA,NA,,
no,AD,DB,DN8234_c0_g1_i1,DN8234_c0_g1,SSBP2_HUMAN,Single-stranded DNA-binding protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,.,NA,NA,NA,NA,KEGG:hsa:23635,ENOG410XPQX^midbrain-hindbrain boundary initiation,.,NA,NA,NA,NA,,
no,AD,DB,DN8234_c0_g1_i2,DN8234_c0_g1,SSBP2_HUMAN,Single-stranded DNA-binding protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,.,NA,NA,NA,NA,KEGG:hsa:23635,ENOG410XPQX^midbrain-hindbrain boundary initiation,.,NA,NA,NA,NA,,
no,AD,DB,DN8234_c0_g1_i3,DN8234_c0_g1,SSBP2_HUMAN,Single-stranded DNA-binding protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,.,NA,NA,NA,NA,KEGG:hsa:23635,ENOG410XPQX^midbrain-hindbrain boundary initiation,.,NA,NA,NA,NA,,
no,AD,DB,DN8234_c0_g2_i1,DN8234_c0_g2,SSBP2_MOUSE,Single-stranded DNA-binding protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,.,NA,NA,NA,NA,KEGG:mmu:66970,ENOG410XPQX^midbrain-hindbrain boundary initiation,.,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i6,DN4531_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,PF00676.20^E1_dh^Dehydrogenase E1 component^1-122^E:1.2e-37,PF00676.20^E1_dh^Dehydrogenase E1 component^124-223^E:3.7e-36,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i4,DN4531_c0_g1,ODBA_MACFA,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0046872^molecular_function^metal ion binding,GO:0009083^biological_process^branched-chain amino acid catabolic process,.,NA,NA,NA,NA,KEGG:mcf:102134149`KO:K00166,.,.,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i9,DN4531_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,PF00676.20^E1_dh^Dehydrogenase E1 component^70-126^E:1.6e-13,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i7,DN4531_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i3,DN4531_c0_g1,ODBA_PANTR,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0046872^molecular_function^metal ion binding,GO:0009083^biological_process^branched-chain amino acid catabolic process,.,NA,NA,NA,NA,KEGG:ptr:468889`KO:K00166,COG1071^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g1_i2,DN4531_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,PF00676.20^E1_dh^Dehydrogenase E1 component^1-244^E:4.1e-92,NA,NA,NA,NA,,
no,AD,DB,DN4531_c0_g2_i1,DN4531_c0_g2,ODBA_MACFA,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0046872^molecular_function^metal ion binding,GO:0009083^biological_process^branched-chain amino acid catabolic process,.,NA,NA,NA,NA,KEGG:mcf:102134149`KO:K00166,.,.,NA,NA,NA,NA,,
no,AD,DB,DN52051_c0_g1_i1,DN52051_c0_g1,DBX2_HUMAN,Homeobox protein DBX2,DBX2_HUMAN,Homeobox protein DBX2,GO:0000790^cellular_component^nuclear chromatin,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0043565^molecular_function^sequence-specific DNA binding,GO:0006357^biological_process^regulation of transcription by RNA polymerase II,NA,GO:0000790^cellular_component^nuclear chromatin,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0043565^molecular_function^sequence-specific DNA binding,GO:0006357^biological_process^regulation of transcription by RNA polymerase II,NA,KEGG:hsa:440097,ENOG411188D^homeobox,PF00046.29^Homeodomain^Homeodomain^196-250^E:4.7e-20,NA,NA,NA,NA,,
no,AD,DB,DN3621_c0_g1_i3,DN3621_c0_g1,UDB31_CANLF,UDP-glucuronosyltransferase 2B31,UDB31_CANLF,UDP-glucuronosyltransferase 2B31,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015020^molecular_function^glucuronosyltransferase activity,GO:0008194^molecular_function^UDP-glycosyltransferase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015020^molecular_function^glucuronosyltransferase activity,GO:0008194^molecular_function^UDP-glycosyltransferase activity,KEGG:cfa:442984`KO:K00699,COG1819^Transferase,PF00201.18^UDPGT^UDP-glucoronosyl and UDP-glucosyl transferase^28-189^E:3.5e-89,PF04101.16^Glyco_tran_28_C^Glycosyltransferase family 28 C-terminal domain^35-104^E:7.1e-07,NA,NA,NA,,
no,AD,DB,DN2717_c3_g1_i5,DN2717_c3_g1,ARI5A_MOUSE,AT-rich interactive domain-containing protein 5A,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:mmu:214855,ENOG4111RDB^AT rich interactive domain 5A (MRF1-like),.,NA,NA,NA,NA,,
no,AD,DB,DN2717_c3_g1_i1,DN2717_c3_g1,ARI5A_MOUSE,AT-rich interactive domain-containing protein 5A,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:mmu:214855,ENOG4111RDB^AT rich interactive domain 5A (MRF1-like),.,NA,NA,NA,NA,,
no,AD,DB,DN2717_c3_g1_i6,DN2717_c3_g1,ARI5A_MOUSE,AT-rich interactive domain-containing protein 5A,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:mmu:214855,ENOG4111RDB^AT rich interactive domain 5A (MRF1-like),.,NA,NA,NA,NA,,
no,AD,DB,DN2717_c3_g1_i4,DN2717_c3_g1,ARI5A_MOUSE,AT-rich interactive domain-containing protein 5A,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:mmu:214855,ENOG4111RDB^AT rich interactive domain 5A (MRF1-like),.,NA,NA,NA,NA,,
no,AD,DB,DN2789_c0_g1_i7,DN2789_c0_g1,DDA1_CHICK,DET1- and DDB1-associated protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426942`KO:K11792,ENOG41120QM^DET1 and DDB1 associated 1,.,NA,NA,NA,NA,,
no,AD,DB,DN2789_c0_g1_i9,DN2789_c0_g1,DDA1_CHICK,DET1- and DDB1-associated protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426942`KO:K11792,ENOG41120QM^DET1 and DDB1 associated 1,.,NA,NA,NA,NA,,
no,AD,DB,DN2789_c0_g1_i5,DN2789_c0_g1,DDA1_CHICK,DET1- and DDB1-associated protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426942`KO:K11792,ENOG41120QM^DET1 and DDB1 associated 1,.,NA,NA,NA,NA,,
no,AD,DB,DN2789_c0_g1_i8,DN2789_c0_g1,DDA1_CHICK,DET1- and DDB1-associated protein 1,DDA1_CHICK,DET1- and DDB1-associated protein 1,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,NA,NA,NA,KEGG:gga:426942`KO:K11792,ENOG41120QM^DET1 and DDB1 associated 1,PF10172.9^DDA1^Det1 complexing ubiquitin ligase^13-75^E:3.7e-30,NA,NA,NA,NA,,
no,AD,DB,DN9420_c0_g1_i1,DN9420_c0_g1,DBLOH_MOUSE,"Diablo homolog, mitochondrial",.,NA,GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:66593`KO:K10522,"ENOG4111KJ0^Diablo, IAP-binding mitochondrial protein",.,NA,NA,NA,NA,,
no,AD,DB,DN9420_c0_g1_i5,DN9420_c0_g1,DBLOH_MOUSE,"Diablo homolog, mitochondrial",DBLOH_MOUSE,"Diablo homolog, mitochondrial",GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,KEGG:mmu:66593`KO:K10522,"ENOG4111KJ0^Diablo, IAP-binding mitochondrial protein",PF09057.10^Smac_DIABLO^Second Mitochondria-derived Activator of Caspases^2-116^E:1.5e-64,NA,NA,NA,NA,,
no,AD,DB,DN9420_c0_g1_i3,DN9420_c0_g1,DBLOH_MOUSE,"Diablo homolog, mitochondrial",DBLOH_MOUSE,"Diablo homolog, mitochondrial",GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,KEGG:mmu:66593`KO:K10522,"ENOG4111KJ0^Diablo, IAP-binding mitochondrial protein",PF09057.10^Smac_DIABLO^Second Mitochondria-derived Activator of Caspases^2-184^E:1.5e-90,NA,NA,NA,NA,,
no,AD,DB,DN9420_c0_g1_i6,DN9420_c0_g1,DBLOH_MOUSE,"Diablo homolog, mitochondrial",DBLOH_MOUSE,"Diablo homolog, mitochondrial",GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,KEGG:mmu:66593`KO:K10522,"ENOG4111KJ0^Diablo, IAP-binding mitochondrial protein",PF09057.10^Smac_DIABLO^Second Mitochondria-derived Activator of Caspases^41-179^E:4.4e-74,NA,NA,NA,NA,,
no,AD,DB,DN66733_c0_g1_i2,DN66733_c0_g1,PCDB4_PANTR,Protocadherin beta-4,PCDB4_PANTR,Protocadherin beta-4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471659`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^1-77^E:3.6e-08,NA,NA,NA,NA,,
no,AD,DB,DN66733_c0_g1_i7,DN66733_c0_g1,PCDB4_PANTR,Protocadherin beta-4,PCDB4_PANTR,Protocadherin beta-4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471659`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^1-77^E:4.3e-09,NA,NA,NA,NA,,
no,AD,DB,DN66733_c0_g1_i6,DN66733_c0_g1,PCDB4_PANTR,Protocadherin beta-4,PCDB4_PANTR,Protocadherin beta-4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471659`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^1-77^E:1e-09,NA,NA,NA,NA,,
no,AD,DB,DN6762_c0_g1_i4,DN6762_c0_g1,M1I1B_DANRE,Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720},.,NA,GO:0005829^cellular_component^cytosol,GO:0005874^cellular_component^microtubule,GO:0005634^cellular_component^nucleus,GO:0046890^biological_process^regulation of lipid biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:dre:393805,ENOG4111NGS^Mid1 interacting protein 1,.,NA,NA,NA,NA,,
no,AD,DB,DN6762_c0_g1_i9,DN6762_c0_g1,M1I1B_DANRE,Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720},M1I1B_DANRE,Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720},GO:0005829^cellular_component^cytosol,GO:0005874^cellular_component^microtubule,GO:0005634^cellular_component^nucleus,GO:0046890^biological_process^regulation of lipid biosynthetic process,NA,GO:0005829^cellular_component^cytosol,GO:0005874^cellular_component^microtubule,GO:0005634^cellular_component^nucleus,GO:0046890^biological_process^regulation of lipid biosynthetic process,NA,KEGG:dre:393805,ENOG4111NGS^Mid1 interacting protein 1,PF07084.12^Spot_14^Thyroid hormone-inducible hepatic protein Spot 14^2-115^E:2.8e-20,NA,NA,NA,NA,,
no,AD,DB,DN6762_c0_g1_i6,DN6762_c0_g1,M1I1B_DANRE,Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720},M1I1B_DANRE,Mid1-interacting protein 1-B {ECO:0000312|ZFIN:ZDB-GENE-040426-1720},GO:0005829^cellular_component^cytosol,GO:0005874^cellular_component^microtubule,GO:0005634^cellular_component^nucleus,GO:0046890^biological_process^regulation of lipid biosynthetic process,NA,GO:0005829^cellular_component^cytosol,GO:0005874^cellular_component^microtubule,GO:0005634^cellular_component^nucleus,GO:0046890^biological_process^regulation of lipid biosynthetic process,NA,KEGG:dre:393805,ENOG4111NGS^Mid1 interacting protein 1,PF07084.12^Spot_14^Thyroid hormone-inducible hepatic protein Spot 14^2-115^E:2.8e-20,NA,NA,NA,NA,,
no,AD,DB,DN23354_c0_g1_i1,DN23354_c0_g1,DCA15_BOVIN,DDB1- and CUL4-associated factor 15,DCA15_BOVIN,DDB1- and CUL4-associated factor 15,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:bta:539970`KO:K11791,ENOG410ZN1V^DDB1 and CUL4 associated factor 15,"PF14939.6^DCAF15_WD40^DDB1-and CUL4-substrate receptor 15, WD repeat^64-271^E:1.7e-79",NA,NA,NA,NA,,
no,AD,DB,DN13540_c0_g1_i2,DN13540_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN30789_c0_g1_i8,DN30789_c0_g1,DBND1_HUMAN,Dysbindin domain-containing protein 1,DBND1_HUMAN,Dysbindin domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,KEGG:hsa:79007,ENOG4111VKB^dysbindin (dystrobrevin binding protein 1) domain containing 1,PF04440.16^Dysbindin^Dysbindin (Dystrobrevin binding protein 1)^72-203^E:5.6e-33,NA,NA,NA,NA,,
no,AD,DB,DN30789_c0_g1_i2,DN30789_c0_g1,DBND1_HUMAN,Dysbindin domain-containing protein 1,DBND1_HUMAN,Dysbindin domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,KEGG:hsa:79007,ENOG4111VKB^dysbindin (dystrobrevin binding protein 1) domain containing 1,PF04440.16^Dysbindin^Dysbindin (Dystrobrevin binding protein 1)^72-179^E:1.5e-35,NA,NA,NA,NA,,
no,AD,DB,DN30789_c0_g2_i1,DN30789_c0_g2,DBND1_XENLA,Dysbindin domain-containing protein 1,DBND1_HUMAN,Dysbindin domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,KEGG:hsa:79007,ENOG4111VKB^dysbindin (dystrobrevin binding protein 1) domain containing 1,PF04440.16^Dysbindin^Dysbindin (Dystrobrevin binding protein 1)^3-115^E:3.6e-26,NA,NA,NA,NA,,
no,AD,DB,DN3938_c0_g1_i1,DN3938_c0_g1,DBR1_CHICK,Lariat debranching enzyme,DBR1_CHICK,Lariat debranching enzyme,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,.,NA,NA,NA,NA,,
no,AD,DB,DN4071_c0_g1_i2,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,DCA13_CHICK,DDB1- and CUL4-associated factor 13,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,"PF00400.32^WD40^WD domain, G-beta repeat^29-55^E:0.0093",PF04158.14^Sof1^Sof1-like domain^56-142^E:2.2e-37,NA,NA,NA,,
no,AD,DB,DN4071_c0_g1_i3,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,.,NA,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,.,NA,NA,NA,NA,,
no,AD,DB,DN4071_c0_g1_i4,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,DCA13_CHICK,DDB1- and CUL4-associated factor 13,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,"PF00400.32^WD40^WD domain, G-beta repeat^118-154^E:0.00036","PF00400.32^WD40^WD domain, G-beta repeat^158-196^E:0.0027","PF00400.32^WD40^WD domain, G-beta repeat^339-368^E:0.051","PF00400.32^WD40^WD domain, G-beta repeat^386-412^E:0.04",PF04158.14^Sof1^Sof1-like domain^413-499^E:2.8e-36,,
no,AD,DB,DN4071_c0_g1_i6,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,.,NA,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,.,NA,NA,NA,NA,,
no,AD,DB,DN4071_c0_g1_i7,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,.,NA,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,.,NA,NA,NA,NA,,
no,AD,DB,DN4071_c0_g1_i1,DN4071_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,DCA13_CHICK,DDB1- and CUL4-associated factor 13,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,"PF00400.32^WD40^WD domain, G-beta repeat^118-154^E:0.00024","PF00400.32^WD40^WD domain, G-beta repeat^158-196^E:0.0018","PF00400.32^WD40^WD domain, G-beta repeat^339-368^E:0.035",NA,NA,,
yes,MJ,DB,DN634_c0_g1_i11,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^49-130^E:9.9e-15,NA,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i4,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i6,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^184-225^E:7.9e-09,NA,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i13,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i8,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i14,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i9,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^121-202^E:2.1e-14,NA,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i7,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_BOVIN,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:bta:282488`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^18-56^E:0.00018,NA,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i10,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_BOVIN,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:bta:282488`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00020.18^TNFR_c6^TNFR/NGFR cysteine-rich region^184-225^E:6.1e-09,NA,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i12,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
yes,MJ,DB,DN634_c0_g1_i3,DN634_c0_g1,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,TNR6_PIG,Tumor necrosis factor receptor superfamily member 6,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005516^molecular_function^calmodulin binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,GO:0006915^biological_process^apoptotic process,KEGG:ssc:396826`KO:K04390,ENOG4112ADB^activation-induced cell death of T cells,PF00531.22^Death^Death domain^30-111^E:7.5e-15,PF00090.19^TSP_1^Thrombospondin type 1 domain^116-139^E:0.2,NA,NA,NA,,
no,AD,DB,DN609_c3_g1_i1,DN609_c3_g1,LDB2_CHICK,LIM domain-binding protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:gga:395631,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN45208_c0_g1_i1,DN45208_c0_g1,PCDB5_PANTR,Protocadherin beta-5,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN45208_c0_g1_i5,DN45208_c0_g1,PCDB5_PANTR,Protocadherin beta-5,PCDB5_PANTR,Protocadherin beta-5,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^3-93^E:8.2e-12,NA,NA,NA,NA,,
no,AD,DB,DN36119_c0_g1_i1,DN36119_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN36119_c0_g1_i18,DN36119_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^80-198^E:6.4e-06,PF00621.20^RhoGEF^RhoGEF domain^631-805^E:4.4e-38,PF00169.29^PH^PH domain^839-940^E:9.3e-09,NA,NA,,
no,AD,DB,DN36119_c0_g1_i7,DN36119_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,PF13716.6^CRAL_TRIO_2^Divergent CRAL/TRIO domain^80-198^E:6.1e-06,PF00621.20^RhoGEF^RhoGEF domain^631-805^E:4.3e-38,PF00169.29^PH^PH domain^839-940^E:8.9e-09,NA,NA,,
no,AD,DB,DN36119_c0_g1_i8,DN36119_c0_g1,.,NA,MCF2L_MOUSE,Guanine nucleotide exchange factor DBS,.,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0012505^cellular_component^endomembrane system,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0019898^cellular_component^extrinsic component of membrane,GO:0030027^cellular_component^lamellipodium,.,.,.,NA,NA,NA,NA,,
no,AD,DB,DN36119_c0_g1_i3,DN36119_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i9,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,"PF00400.32^WD40^WD domain, G-beta repeat^101-137^E:0.0091","PF00400.32^WD40^WD domain, G-beta repeat^145-180^E:0.00049",NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i8,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,"PF00400.32^WD40^WD domain, G-beta repeat^101-137^E:0.0093","PF00400.32^WD40^WD domain, G-beta repeat^145-180^E:0.0005",NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i2,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,DCA10_XENTR,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:xtr:548459`KO:K11802,ENOG410ZF1A^DDB1 and CUL4 associated factor 10,PF12894.7^ANAPC4_WD40^Anaphase-promoting complex subunit 4 WD40 domain^65-119^E:0.00029,"PF00400.32^WD40^WD domain, G-beta repeat^101-137^E:0.0064","PF00400.32^WD40^WD domain, G-beta repeat^145-180^E:0.00035",NA,NA,,
no,AD,DB,DN11837_c0_g1_i7,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,DCA10_XENLA,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:xla:379080`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i4,DN11837_c0_g1,DCA10_XENLA,DDB1- and CUL4-associated factor 10,DCA10_XENLA,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:xla:379080`KO:K11802,.,.,NA,NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i5,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN11837_c0_g1_i3,DN11837_c0_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN11837_c1_g1_i2,DN11837_c1_g1,DCA10_HUMAN,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:79269`KO:K11802,ENOG410ZF1A^DDB1 and CUL4 associated factor 10,.,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i14,DN11956_c0_g1,CCD73_HUMAN,Coiled-coil domain-containing protein 73,CCD73_HUMAN,Coiled-coil domain-containing protein 73,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:493860,ENOG4112DB3^coiled-coil domain containing 73,PF15818.5^CCDC73^Coiled-coil domain-containing protein 73 family^1-172^E:2.2e-80,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i9,DN11956_c0_g1,CCD73_MOUSE,Coiled-coil domain-containing protein 73,.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:211936,ENOG4112DB3^coiled-coil domain containing 73,.,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i1,DN11956_c0_g1,CCD73_HUMAN,Coiled-coil domain-containing protein 73,CCD73_HUMAN,Coiled-coil domain-containing protein 73,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:493860,ENOG4112DB3^coiled-coil domain containing 73,PF15818.5^CCDC73^Coiled-coil domain-containing protein 73 family^26-312^E:8.6e-159,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i7,DN11956_c0_g1,CCD73_HUMAN,Coiled-coil domain-containing protein 73,CCD73_HUMAN,Coiled-coil domain-containing protein 73,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:493860,ENOG4112DB3^coiled-coil domain containing 73,PF15818.5^CCDC73^Coiled-coil domain-containing protein 73 family^26-299^E:4.1e-143,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i2,DN11956_c0_g1,CCD73_HUMAN,Coiled-coil domain-containing protein 73,CCD73_HUMAN,Coiled-coil domain-containing protein 73,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:493860,ENOG4112DB3^coiled-coil domain containing 73,PF15818.5^CCDC73^Coiled-coil domain-containing protein 73 family^1-566^E:1.5e-139,NA,NA,NA,NA,,
no,AD,DB,DN11956_c0_g1_i10,DN11956_c0_g1,CCD73_HUMAN,Coiled-coil domain-containing protein 73,CCD73_HUMAN,Coiled-coil domain-containing protein 73,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:493860,ENOG4112DB3^coiled-coil domain containing 73,PF15818.5^CCDC73^Coiled-coil domain-containing protein 73 family^31-98^E:2.3e-37,NA,NA,NA,NA,,
no,AD,DB,DN27125_c0_g1_i2,DN27125_c0_g1,M4GDB_DANRE,MIF4G domain-containing protein B,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,GO:0008494^molecular_function^translation activator activity,.,NA,NA,NA,NA,KEGG:dre:503596,ENOG410XQKW^CBP80 20-dependent translation initiation factor,.,NA,NA,NA,NA,,
no,AD,DB,DN7976_c0_g1_i6,DN7976_c0_g1,DBND2_MOUSE,Dysbindin domain-containing protein 2,DTBP1_CHICK,Dysbindin,GO:0005737^cellular_component^cytoplasm,GO:0006469^biological_process^negative regulation of protein kinase activity,NA,NA,NA,GO:0030424^cellular_component^axon,GO:1904115^cellular_component^axon cytoplasm,GO:0031083^cellular_component^BLOC-1 complex,GO:0030054^cellular_component^cell junction,GO:0043197^cellular_component^dendritic spine,KEGG:gga:420840`KO:K20189,ENOG4111YM1^dystrobrevin binding protein 1,PF04440.16^Dysbindin^Dysbindin (Dystrobrevin binding protein 1)^79-180^E:1e-37,NA,NA,NA,NA,,
no,MJ,DB,DN8033_c0_g1_i5,DN8033_c0_g1,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,KEGG:ddi:DDB_G0293006,ENOG410Y2DF^leucine-zipper-like transcription regulator 1,PF13854.6^Kelch_5^Kelch motif^26-60^E:1.3e-05,PF13964.6^Kelch_6^Kelch motif^29-67^E:2.9e-07,PF01344.25^Kelch_1^Kelch motif^29-67^E:1.2e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^29-68^E:1.1e-08","PF13415.6^Kelch_3^Galactose oxidase, central domain^40-74^E:3.9e-05",,
no,MJ,DB,DN8033_c0_g1_i6,DN8033_c0_g1,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,KEGG:ddi:DDB_G0293006,ENOG410Y2DF^leucine-zipper-like transcription regulator 1,PF13854.6^Kelch_5^Kelch motif^26-60^E:1.3e-05,PF13964.6^Kelch_6^Kelch motif^29-67^E:2.9e-07,PF01344.25^Kelch_1^Kelch motif^29-67^E:1.2e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^29-68^E:1.1e-08","PF13415.6^Kelch_3^Galactose oxidase, central domain^40-74^E:3.9e-05",,
no,MJ,DB,DN8033_c0_g1_i7,DN8033_c0_g1,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GEFF_DICDI,Ras guanine nucleotide exchange factor F,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,KEGG:ddi:DDB_G0293006,ENOG410Y2DF^leucine-zipper-like transcription regulator 1,PF13854.6^Kelch_5^Kelch motif^26-60^E:1.3e-05,PF13964.6^Kelch_6^Kelch motif^29-67^E:2.9e-07,PF01344.25^Kelch_1^Kelch motif^29-67^E:1.2e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^29-68^E:1.1e-08","PF13415.6^Kelch_3^Galactose oxidase, central domain^40-74^E:3.9e-05",,
no,MJ,DB,DN8033_c0_g1_i15,DN8033_c0_g1,GEFF_DICDI,Ras guanine nucleotide exchange factor F,.,NA,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0293006,ENOG410Y2DF^leucine-zipper-like transcription regulator 1,PF13854.6^Kelch_5^Kelch motif^30-67^E:5.4e-07,PF13964.6^Kelch_6^Kelch motif^35-78^E:8.8e-06,NA,NA,NA,,
no,AD,DB,DN10019_c0_g1_i1,DN10019_c0_g1,RPB1_DICDI,DNA-directed RNA polymerase II subunit rpb1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0005665^cellular_component^RNA polymerase II, core complex",GO:0003677^molecular_function^DNA binding,GO:0003899^molecular_function^DNA-directed 5'-3' RNA polymerase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279193`KO:K03006,COG0086^DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN10019_c0_g1_i9,DN10019_c0_g1,RPB1_DICDI,DNA-directed RNA polymerase II subunit rpb1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0005665^cellular_component^RNA polymerase II, core complex",GO:0003677^molecular_function^DNA binding,GO:0003899^molecular_function^DNA-directed 5'-3' RNA polymerase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279193`KO:K03006,COG0086^DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN10019_c0_g1_i3,DN10019_c0_g1,RPB1_DICDI,DNA-directed RNA polymerase II subunit rpb1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0005665^cellular_component^RNA polymerase II, core complex",GO:0003677^molecular_function^DNA binding,GO:0003899^molecular_function^DNA-directed 5'-3' RNA polymerase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279193`KO:K03006,COG0086^DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN10014_c0_g1_i5,DN10014_c0_g1,DCAF8_PONAB,DDB1- and CUL4-associated factor 8,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:50717`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN10014_c0_g1_i2,DN10014_c0_g1,DCAF8_PONAB,DDB1- and CUL4-associated factor 8,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:pon:100174058`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN10014_c0_g1_i4,DN10014_c0_g1,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:50717`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN10014_c0_g1_i3,DN10014_c0_g1,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:50717`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN94304_c0_g1_i1,DN94304_c0_g1,PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,KEGG:ptr:462130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^66-157^E:8.8e-20,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i11,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i12,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i16,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i3,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i5,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN5204_c0_g1_i24,DN5204_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN2520_c0_g1_i4,DN2520_c0_g1,DCAF7_MOUSE,DDB1- and CUL4-associated factor 7,DCAF7_MOUSE,DDB1- and CUL4-associated factor 7,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016604^cellular_component^nuclear body,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016604^cellular_component^nuclear body,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:71833`KO:K11805,ENOG410XQ78^ddb1 and cul4 associated factor 7,"PF00400.32^WD40^WD domain, G-beta repeat^259-295^E:0.035",NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i8,DN9287_c0_g1,DCA17_MOUSE,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^38-293^E:1.1e-108,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i9,DN9287_c0_g1,DCA17_MOUSE,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^1-141^E:9.5e-56,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i10,DN9287_c0_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^1-171^E:1.6e-73,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i5,DN9287_c0_g1,DCA17_MOUSE,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^2-83^E:9.6e-35,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i3,DN9287_c0_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i12,DN9287_c0_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^1-171^E:1.6e-73,NA,NA,NA,NA,,
no,AD,DB,DN9287_c0_g1_i7,DN9287_c0_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,PF15802.5^DCAF17^DDB1- and CUL4-associated factor 17^1-171^E:1.6e-73,NA,NA,NA,NA,,
no,AD,DB,DN9291_c0_g1_i1,DN9291_c0_g1,ODBB_BOVIN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",ODBB_BOVIN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0009083^biological_process^branched-chain amino acid catabolic process,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0009083^biological_process^branched-chain amino acid catabolic process,KEGG:bta:282150`KO:K00167,.,"PF02779.24^Transket_pyr^Transketolase, pyrimidine binding domain^46-221^E:2.5e-43","PF02780.20^Transketolase_C^Transketolase, C-terminal domain^238-356^E:2.2e-35",NA,NA,NA,,
no,AD,DB,DN9291_c0_g1_i4,DN9291_c0_g1,ODBB_HUMAN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",ODBB_HUMAN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,KEGG:hsa:594`KO:K00167,"COG0022^Dehydrogenase, E1 component",.,NA,NA,NA,NA,,
no,AD,DB,DN9291_c0_g1_i5,DN9291_c0_g1,ODBB_BOVIN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",ODBB_BOVIN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0009083^biological_process^branched-chain amino acid catabolic process,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0009083^biological_process^branched-chain amino acid catabolic process,KEGG:bta:282150`KO:K00167,.,"PF02779.24^Transket_pyr^Transketolase, pyrimidine binding domain^46-221^E:2.5e-43","PF02780.20^Transketolase_C^Transketolase, C-terminal domain^238-356^E:2.2e-35",NA,NA,NA,,
no,AD,DB,DN9291_c0_g1_i8,DN9291_c0_g1,ODBB_HUMAN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",ODBB_HUMAN,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,KEGG:hsa:594`KO:K00167,"COG0022^Dehydrogenase, E1 component",.,NA,NA,NA,NA,,
no,AD,DB,DN22107_c0_g1_i1,DN22107_c0_g1,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN22107_c1_g1_i1,DN22107_c1_g1,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN13049_c1_g1_i1,DN13049_c1_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN21307_c0_g1_i10,DN21307_c0_g1,DBNL_HUMAN,Drebrin-like protein,DBNL_HUMAN,Drebrin-like protein,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,KEGG:hsa:28988`KO:K20520,ENOG410XRVX^Drebrin-like,PF00241.20^Cofilin_ADF^Cofilin/tropomyosin-type actin-binding protein^25-141^E:5.4e-19,NA,NA,NA,NA,,
no,AD,DB,DN21307_c0_g1_i5,DN21307_c0_g1,DBNLA_XENLA,Drebrin-like protein A,.,NA,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,.,NA,NA,NA,NA,KEGG:xla:379806`KO:K20520,.,.,NA,NA,NA,NA,,
no,AD,DB,DN21307_c0_g1_i8,DN21307_c0_g1,DBNL_HUMAN,Drebrin-like protein,.,NA,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,.,NA,NA,NA,NA,KEGG:hsa:28988`KO:K20520,ENOG410XRVX^Drebrin-like,.,NA,NA,NA,NA,,
no,AD,DB,DN21307_c0_g1_i9,DN21307_c0_g1,DBNL_HUMAN,Drebrin-like protein,DBNL_HUMAN,Drebrin-like protein,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,KEGG:hsa:28988`KO:K20520,ENOG410XRVX^Drebrin-like,PF00241.20^Cofilin_ADF^Cofilin/tropomyosin-type actin-binding protein^24-96^E:1.1e-09,NA,NA,NA,NA,,
no,AD,DB,DN71181_c0_g1_i1,DN71181_c0_g1,PCDBD_PANTR,Protocadherin beta-13,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN71181_c1_g1_i1,DN71181_c1_g1,PCDB7_HUMAN,Protocadherin beta-7,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:hsa:56129`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN36854_c0_g1_i2,DN36854_c0_g1,MOXD1_CHICK,DBH-like monooxygenase protein 1,MOXD1_CHICK,DBH-like monooxygenase protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,KEGG:gga:395333,ENOG410XR89^dopamine beta-hydroxylase (dopamine beta-monooxygenase),PF03351.17^DOMON^DOMON domain^51-162^E:2e-28,"PF01082.20^Cu2_monooxygen^Copper type II ascorbate-dependent monooxygenase, N-terminal domain^201-327^E:4.1e-49","PF03712.15^Cu2_monoox_C^Copper type II ascorbate-dependent monooxygenase, C-terminal domain^348-496^E:5.9e-43",NA,NA,,
no,AD,DB,DN36854_c0_g1_i1,DN36854_c0_g1,MOXD1_CHICK,DBH-like monooxygenase protein 1,MOXD1_CHICK,DBH-like monooxygenase protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,KEGG:gga:395333,ENOG410XR89^dopamine beta-hydroxylase (dopamine beta-monooxygenase),PF03351.17^DOMON^DOMON domain^51-162^E:1.1e-28,"PF01082.20^Cu2_monooxygen^Copper type II ascorbate-dependent monooxygenase, N-terminal domain^201-327^E:2.3e-49","PF03712.15^Cu2_monoox_C^Copper type II ascorbate-dependent monooxygenase, C-terminal domain^348-449^E:1.3e-20",NA,NA,,
no,AD,DB,DN36854_c0_g1_i3,DN36854_c0_g1,MOXD1_CHICK,DBH-like monooxygenase protein 1,MOXD1_CHICK,DBH-like monooxygenase protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030667^cellular_component^secretory granule membrane,KEGG:gga:395333,ENOG410XR89^dopamine beta-hydroxylase (dopamine beta-monooxygenase),.,NA,NA,NA,NA,,
no,AD,DB,DN36838_c2_g1_i1,DN36838_c2_g1,DCAF5_MOUSE,DDB1- and CUL4-associated factor 5,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005739^cellular_component^mitochondrion,GO:0016567^biological_process^protein ubiquitination,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:320808`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,.,NA,NA,NA,NA,,
no,AD,DB,DN87547_c0_g1_i4,DN87547_c0_g1,DCA17_RAT,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:rno:499807`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN87547_c0_g1_i5,DN87547_c0_g1,DCA17_RAT,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:rno:499807`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN87547_c0_g1_i1,DN87547_c0_g1,DCA17_HUMAN,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:80067`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN87547_c0_g1_i3,DN87547_c0_g1,DCA17_RAT,DDB1- and CUL4-associated factor 17,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:rno:499807`KO:K23331,ENOG410ZP18^DDB1 and CUL4 associated factor 17,.,NA,NA,NA,NA,,
no,AD,DB,DN20582_c0_g1_i1,DN20582_c0_g1,DCAF6_MOUSE,DDB1- and CUL4-associated factor 6,DCAF6_MOUSE,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,KEGG:mmu:74106`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN62048_c0_g1_i1,DN62048_c0_g1,ADB4C_MELGA,Beta-4C adrenergic receptor,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004940^molecular_function^beta1-adrenergic receptor activity,GO:0007189^biological_process^adenylate cyclase-activating G protein-coupled receptor signaling pathway,GO:0045823^biological_process^positive regulation of heart contraction,.,NA,NA,NA,NA,KEGG:mgp:100379211`KO:K04143,ENOG410XRW9^Receptor,.,NA,NA,NA,NA,,
no,AD,DB,DN3746_c1_g1_i3,DN3746_c1_g1,DLRB1_HUMAN,Dynein light chain roadblock-type 1,.,NA,GO:0005813^cellular_component^centrosome,GO:0097542^cellular_component^ciliary tip,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,.,NA,NA,NA,NA,KEGG:hsa:83658`KO:K10419,"ENOG4111NDV^dynein, light chain",.,NA,NA,NA,NA,,
no,AD,DB,DN3746_c1_g1_i2,DN3746_c1_g1,DLRB1_HUMAN,Dynein light chain roadblock-type 1,DLRB1_HUMAN,Dynein light chain roadblock-type 1,GO:0005813^cellular_component^centrosome,GO:0097542^cellular_component^ciliary tip,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005813^cellular_component^centrosome,GO:0097542^cellular_component^ciliary tip,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,KEGG:hsa:83658`KO:K10419,"ENOG4111NDV^dynein, light chain",PF03259.17^Robl_LC7^Roadblock/LC7 domain^4-85^E:1.4e-22,NA,NA,NA,NA,,
no,AD,DB,DN70318_c0_g4_i1,DN70318_c0_g4,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN10640_c3_g1_i1,DN10640_c3_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN10640_c3_g1_i2,DN10640_c3_g1,DCA10_MOUSE,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:242418`KO:K11802,ENOG410XP1Z^wD repeat domain,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i17,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i1,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},.,NA,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i24,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},.,NA,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i26,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_MOUSE,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF18300.1^DUF5604^Domain of unknown function (DUF5604)^417-474^E:6.5e-37,PF18359.1^TUDOR_5^Histone methyltransferase Tudor domain 1^483-531^E:1.2e-20,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^572-621^E:1.5e-26,NA,NA,,
no,AD,DB,DN2890_c0_g1_i3,DN2890_c0_g1,SETB1_MOUSE,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_MOUSE,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,COG2940^Histone-lysine N-methyltransferase,PF18300.1^DUF5604^Domain of unknown function (DUF5604)^70-127^E:1.5e-37,PF18359.1^TUDOR_5^Histone methyltransferase Tudor domain 1^136-184^E:3e-21,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^225-274^E:3.7e-27,NA,NA,,
no,AD,DB,DN2890_c0_g1_i21,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i20,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},.,NA,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i4,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF00856.28^SET^SET domain^24-165^E:8.1e-11,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i19,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_MOUSE,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF18300.1^DUF5604^Domain of unknown function (DUF5604)^417-474^E:6.5e-37,PF18359.1^TUDOR_5^Histone methyltransferase Tudor domain 1^483-531^E:1.2e-20,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^572-621^E:1.5e-26,NA,NA,,
no,AD,DB,DN2890_c0_g1_i10,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^2-17^E:1.2e-06,PF01429.19^MBD^Methyl-CpG binding domain^201-272^E:1.3e-12,PF05033.16^Pre-SET^Pre-SET motif^288-401^E:6.4e-16,PF00856.28^SET^SET domain^420-561^E:3.8e-12,NA,,
no,AD,DB,DN2890_c0_g1_i30,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i6,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_MOUSE,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF18300.1^DUF5604^Domain of unknown function (DUF5604)^89-146^E:3.5e-37,PF18359.1^TUDOR_5^Histone methyltransferase Tudor domain 1^155-203^E:6.5e-21,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^244-293^E:8.1e-27,NA,NA,,
no,AD,DB,DN2890_c0_g1_i27,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF00856.28^SET^SET domain^116-262^E:3.4e-21,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i22,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF18358.1^Tudor_4^Histone methyltransferase Tudor domain^2-17^E:1.5e-06,PF01429.19^MBD^Methyl-CpG binding domain^201-272^E:1.7e-12,PF05033.16^Pre-SET^Pre-SET motif^288-401^E:9.1e-16,PF00856.28^SET^SET domain^420-561^E:3.4e-11,NA,,
no,AD,DB,DN2890_c0_g1_i29,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i25,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i15,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},.,NA,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN2890_c0_g1_i2,DN2890_c0_g1,SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},SETB1_HUMAN,Histone-lysine N-methyltransferase SETDB1 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:9869`KO:K11421,COG2940^Histone-lysine N-methyltransferase,PF00856.28^SET^SET domain^24-165^E:8e-12,NA,NA,NA,NA,,
no,AD,DB,DN6804_c0_g2_i1,DN6804_c0_g2,DKC1_CHICK,H/ACA ribonucleoprotein complex subunit DKC1,DKC1_DICDI,Probable H/ACA ribonucleoprotein complex subunit 4,GO:0031429^cellular_component^box H/ACA snoRNP complex,GO:0015030^cellular_component^Cajal body,GO:0005654^cellular_component^nucleoplasm,GO:0005697^cellular_component^telomerase holoenzyme complex,GO:0009982^molecular_function^pseudouridine synthase activity,GO:0031429^cellular_component^box H/ACA snoRNP complex,GO:0005730^cellular_component^nucleolus,GO:0005697^cellular_component^telomerase holoenzyme complex,GO:0009982^molecular_function^pseudouridine synthase activity,GO:0003723^molecular_function^RNA binding,KEGG:ddi:DDB_G0281933`KO:K11131,COG0130^Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity),PF16198.5^TruB_C_2^tRNA pseudouridylate synthase B C-terminal domain^1-30^E:3e-08,NA,NA,NA,NA,,
no,AD,DB,DN57983_c0_g1_i1,DN57983_c0_g1,RD21L_HUMAN,Double-strand-break repair protein rad21-like protein 1,.,NA,GO:0005694^cellular_component^chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:642636,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN24416_c0_g1_i1,DN24416_c0_g1,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4148_c0_g1_i7,DN4148_c0_g1,GFRP_MOUSE,GTP cyclohydrolase 1 feedback regulatory protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0042470^cellular_component^melanosome,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:mmu:320415,ENOG4111X10^GTP cyclohydrolase I feedback regulator,.,NA,NA,NA,NA,,
no,AD,DB,DN3217_c0_g1_i3,DN3217_c0_g1,LDB1_CHICK,LIM domain-binding protein 1,LDB1_CHICK,LIM domain-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,KEGG:gga:395952`KO:K15617,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^144-293^E:5.6e-42,PF01803.16^LIM_bind^LIM-domain binding protein^295-346^E:2e-11,NA,NA,NA,,
no,AD,DB,DN3217_c0_g1_i4,DN3217_c0_g1,LDB1_XENLA,LIM domain-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:xla:380241`KEGG:xla:779363`KO:K15617,.,.,NA,NA,NA,NA,,
no,AD,DB,DN3217_c0_g1_i1,DN3217_c0_g1,LDB1_XENLA,LIM domain-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:xla:380241`KEGG:xla:779363`KO:K15617,.,.,NA,NA,NA,NA,,
no,AD,DB,DN3217_c0_g1_i6,DN3217_c0_g1,LDB1_CHICK,LIM domain-binding protein 1,LDB1_CHICK,LIM domain-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,KEGG:gga:395952`KO:K15617,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^144-293^E:4.9e-42,PF01803.16^LIM_bind^LIM-domain binding protein^295-346^E:1.8e-11,NA,NA,NA,,
no,AD,DB,DN3217_c0_g1_i2,DN3217_c0_g1,LDB1_CHICK,LIM domain-binding protein 1,LDB1_CHICK,LIM domain-binding protein 1,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,KEGG:gga:395952`KO:K15617,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^144-293^E:6.2e-42,PF01803.16^LIM_bind^LIM-domain binding protein^295-346^E:2.1e-11,PF17916.1^LID^LIM interaction domain (LID)^411-439^E:4.5e-18,NA,NA,,
no,AD,DB,DN21975_c0_g1_i1,DN21975_c0_g1,ADB4C_MELGA,Beta-4C adrenergic receptor,ADB4C_MELGA,Beta-4C adrenergic receptor,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004940^molecular_function^beta1-adrenergic receptor activity,GO:0007189^biological_process^adenylate cyclase-activating G protein-coupled receptor signaling pathway,GO:0045823^biological_process^positive regulation of heart contraction,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004940^molecular_function^beta1-adrenergic receptor activity,GO:0007189^biological_process^adenylate cyclase-activating G protein-coupled receptor signaling pathway,GO:0045823^biological_process^positive regulation of heart contraction,KEGG:mgp:100379211`KO:K04143,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^2-59^E:3.6e-17,NA,NA,NA,NA,,
no,AD,DB,DN63510_c0_g1_i2,DN63510_c0_g1,DCAF8_PONAB,DDB1- and CUL4-associated factor 8,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:pon:100174058`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN63510_c0_g1_i1,DN63510_c0_g1,DCAF8_PONAB,DDB1- and CUL4-associated factor 8,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:pon:100174058`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN11129_c1_g2_i2,DN11129_c1_g2,KC1DB_DANRE,Casein kinase I isoform delta-B,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005876^cellular_component^spindle microtubule,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,.,NA,NA,NA,NA,KEGG:dre:406533`KO:K08959,ENOG410XPGP^Casein Kinase,.,NA,NA,NA,NA,,
no,AD,DB,DN95367_c0_g1_i1,DN95367_c0_g1,DBR1_CHICK,Lariat debranching enzyme,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",.,NA,NA,NA,NA,KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,.,NA,NA,NA,NA,,
no,AD,DB,DN95367_c1_g1_i1,DN95367_c1_g1,DBR1_CHICK,Lariat debranching enzyme,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",.,NA,NA,NA,NA,KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,.,NA,NA,NA,NA,,
no,AD,DB,DN35671_c0_g1_i2,DN35671_c0_g1,ZN346_DANRE,Zinc finger protein 346 {ECO:0000312|ZFIN:ZDB-GENE-070209-152},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003725^molecular_function^double-stranded RNA binding,GO:0008270^molecular_function^zinc ion binding,NA,.,NA,NA,NA,NA,KEGG:dre:560756,ENOG4111JFP^Zinc finger protein 346,.,NA,NA,NA,NA,,
no,AD,DB,DN85450_c0_g1_i1,DN85450_c0_g1,PCDB5_PANTR,Protocadherin beta-5,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN85450_c0_g2_i1,DN85450_c0_g2,PCDB1_HUMAN,Protocadherin beta-1,PCDB1_HUMAN,Protocadherin beta-1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:hsa:29930`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^44-133^E:1.9e-17,NA,NA,NA,NA,,
no,AD,DB,DN85450_c0_g2_i2,DN85450_c0_g2,PCDBF_PANTR,Protocadherin beta-15,PCDBF_PANTR,Protocadherin beta-15,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^44-134^E:2.7e-18,NA,NA,NA,NA,,
no,AD,DB,DN85450_c0_g3_i1,DN85450_c0_g3,PCDB8_PANTR,Protocadherin beta-8 {ECO:0000305},.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN85507_c0_g1_i1,DN85507_c0_g1,DCA10_XENTR,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xtr:548459`KO:K11802,ENOG410ZF1A^DDB1 and CUL4 associated factor 10,.,NA,NA,NA,NA,,
no,AD,DB,DN3571_c0_g1_i9,DN3571_c0_g1,ZXDB_HUMAN,Zinc finger X-linked protein ZXDB,ZXDB_HUMAN,Zinc finger X-linked protein ZXDB,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,NA,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,NA,NA,KEGG:hsa:158586,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
no,AD,DB,DN3570_c0_g1_i1,DN3570_c0_g1,NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:145957`KO:K05458,ENOG410ZDBT^Neuregulin 4,.,NA,NA,NA,NA,,
no,AD,DB,DN3570_c0_g1_i3,DN3570_c0_g1,NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:145957`KO:K05458,ENOG410ZDBT^Neuregulin 4,.,NA,NA,NA,NA,,
no,AD,DB,DN3570_c0_g1_i2,DN3570_c0_g1,NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:145957`KO:K05458,ENOG410ZDBT^Neuregulin 4,.,NA,NA,NA,NA,,
no,AD,DB,DN3570_c0_g1_i5,DN3570_c0_g1,NRG4_HUMAN,"Pro-neuregulin-4, membrane-bound isoform",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:145957`KO:K05458,ENOG410ZDBT^Neuregulin 4,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g2_i10,DN1712_c0_g2,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,DCAF4_BOVIN,DDB1- and CUL4-associated factor 4,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:bta:511629`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g2_i4,DN1712_c0_g2,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g2_i3,DN1712_c0_g2,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,DCAF4_BOVIN,DDB1- and CUL4-associated factor 4,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,KEGG:bta:511629`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g2_i12,DN1712_c0_g2,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g2_i2,DN1712_c0_g2,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,DCAF4_HUMAN,DDB1- and CUL4-associated factor 4,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:hsa:26094`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN1712_c0_g3_i1,DN1712_c0_g3,DCAF4_BOVIN,DDB1- and CUL4-associated factor 4,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:511629`KO:K11799,ENOG410XQIU^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN56733_c0_g1_i1,DN56733_c0_g1,DDB1_RAT,DNA damage-binding protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,.,ENOG410XPF6^DNA- binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN6621_c0_g1_i4,DN6621_c0_g1,GRWD1_RAT,Glutamate-rich WD repeat-containing protein 1,GRWD1_RAT,Glutamate-rich WD repeat-containing protein 1,GO:0005694^cellular_component^chromosome,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0003688^molecular_function^DNA replication origin binding,GO:0005694^cellular_component^chromosome,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0003688^molecular_function^DNA replication origin binding,KEGG:rno:308592`KO:K14848,ENOG410XPDB^Glutamate-rich wd repeat-containing protein,"PF00400.32^WD40^WD domain, G-beta repeat^80-115^E:1.8e-05","PF00400.32^WD40^WD domain, G-beta repeat^131-161^E:9.7e-06","PF00400.32^WD40^WD domain, G-beta repeat^169-207^E:0.012",NA,NA,,
no,AD,DB,DN6621_c0_g1_i7,DN6621_c0_g1,GRWD1_RAT,Glutamate-rich WD repeat-containing protein 1,GRWD1_RAT,Glutamate-rich WD repeat-containing protein 1,GO:0005694^cellular_component^chromosome,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0003688^molecular_function^DNA replication origin binding,GO:0005694^cellular_component^chromosome,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0003688^molecular_function^DNA replication origin binding,KEGG:rno:308592`KO:K14848,ENOG410XPDB^Glutamate-rich wd repeat-containing protein,"PF00400.32^WD40^WD domain, G-beta repeat^80-115^E:1.8e-05","PF00400.32^WD40^WD domain, G-beta repeat^131-161^E:9.7e-06","PF00400.32^WD40^WD domain, G-beta repeat^169-207^E:0.012",NA,NA,,
no,AD,DB,DN6693_c0_g2_i6,DN6693_c0_g2,PCDB4_PANTR,Protocadherin beta-4,PCDB4_PANTR,Protocadherin beta-4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471659`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF08266.12^Cadherin_2^Cadherin-like^116-197^E:2.8e-28,PF00028.17^Cadherin^Cadherin domain^224-319^E:2.6e-10,PF00028.17^Cadherin^Cadherin domain^333-423^E:1.3e-18,PF00028.17^Cadherin^Cadherin domain^441-528^E:1.2e-12,PF00028.17^Cadherin^Cadherin domain^543-638^E:1.5e-15,,
no,AD,DB,DN6693_c0_g2_i4,DN6693_c0_g2,PCDB4_PANTR,Protocadherin beta-4,PCDB4_PANTR,Protocadherin beta-4,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471659`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^2-83^E:2.5e-16,PF00028.17^Cadherin^Cadherin domain^101-188^E:6e-13,PF00028.17^Cadherin^Cadherin domain^203-298^E:7.4e-16,PF00028.17^Cadherin^Cadherin domain^325-409^E:2.1e-09,PF16492.5^Cadherin_C_2^Cadherin cytoplasmic C-terminal^431-513^E:3.1e-17,,
no,AD,DB,DN6693_c2_g1_i1,DN6693_c2_g1,PCDB1_PANTR,Protocadherin beta-1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:ptr:471658`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN5790_c0_g1_i1,DN5790_c0_g1,DCAF8_RAT,DDB1- and CUL4-associated factor 8,DCAF8_MOUSE,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:98193`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^7-33^E:0.0073",NA,NA,NA,NA,,
no,AD,DB,DN5790_c0_g1_i6,DN5790_c0_g1,DCAF8_HUMAN,DDB1- and CUL4-associated factor 8,DCAF8_MOUSE,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:98193`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^103-140^E:8.4e-07",NA,NA,NA,NA,,
no,AD,DB,DN5790_c0_g1_i2,DN5790_c0_g1,DCAF8_RAT,DDB1- and CUL4-associated factor 8,DCAF8_RAT,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:rno:364050`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^105-142^E:0.015","PF00400.32^WD40^WD domain, G-beta repeat^154-185^E:0.011",NA,NA,NA,,
no,AD,DB,DN5790_c0_g1_i3,DN5790_c0_g1,DCAF8_MOUSE,DDB1- and CUL4-associated factor 8,DCAF8_MOUSE,DDB1- and CUL4-associated factor 8,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:98193`KO:K11804,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^103-140^E:1.2e-06","PF00400.32^WD40^WD domain, G-beta repeat^344-381^E:0.039","PF00400.32^WD40^WD domain, G-beta repeat^393-424^E:0.027",NA,NA,,
no,AD,DB,DN13384_c0_g1_i8,DN13384_c0_g1,ADDB_HUMAN,Beta-adducin,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0008290^cellular_component^F-actin capping protein complex,GO:0044853^cellular_component^plasma membrane raft,.,NA,NA,NA,NA,KEGG:hsa:119`KO:K18622,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DB,DN13384_c0_g1_i2,DN13384_c0_g1,ADDB_HUMAN,Beta-adducin,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0008290^cellular_component^F-actin capping protein complex,GO:0044853^cellular_component^plasma membrane raft,.,NA,NA,NA,NA,KEGG:hsa:119`KO:K18622,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DB,DN13384_c0_g1_i4,DN13384_c0_g1,ADDB_HUMAN,Beta-adducin,ADDB_HUMAN,Beta-adducin,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0008290^cellular_component^F-actin capping protein complex,GO:0044853^cellular_component^plasma membrane raft,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005856^cellular_component^cytoskeleton,GO:0005829^cellular_component^cytosol,GO:0008290^cellular_component^F-actin capping protein complex,GO:0044853^cellular_component^plasma membrane raft,KEGG:hsa:119`KO:K18622,COG0235^Class II aldolase adducin,PF00596.21^Aldolase_II^Class II Aldolase and Adducin N-terminal domain^136-317^E:7.4e-33,NA,NA,NA,NA,,
no,AD,DB,DN13384_c1_g1_i1,DN13384_c1_g1,ADDB_PONAB,Beta-adducin,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0008290^cellular_component^F-actin capping protein complex,GO:0044853^cellular_component^plasma membrane raft,GO:0014069^cellular_component^postsynaptic density,GO:0051015^molecular_function^actin filament binding,.,NA,NA,NA,NA,KEGG:pon:100174677`KO:K18622,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i10,DN146_c0_g1,DCA12_MACFA,DDB1- and CUL4-associated factor 12,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i3,DN146_c0_g1,CTK2_XENLA,Carboxy-terminal kinesin 2,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005524^molecular_function^ATP binding,GO:0008017^molecular_function^microtubule binding,GO:0003777^molecular_function^microtubule motor activity,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i4,DN146_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,DCA12_CHICK,DDB1- and CUL4-associated factor 12,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i9,DN146_c0_g1,CTK2_XENLA,Carboxy-terminal kinesin 2,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005524^molecular_function^ATP binding,GO:0008017^molecular_function^microtubule binding,GO:0003777^molecular_function^microtubule motor activity,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i2,DN146_c0_g1,CTK2_XENLA,Carboxy-terminal kinesin 2,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005524^molecular_function^ATP binding,GO:0008017^molecular_function^microtubule binding,GO:0003777^molecular_function^microtubule motor activity,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i8,DN146_c0_g1,DCA12_MACFA,DDB1- and CUL4-associated factor 12,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN146_c0_g1_i1,DN146_c0_g1,CTK2_XENLA,Carboxy-terminal kinesin 2,DCA12_MOUSE,DDB1- and CUL4-associated factor 12,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005524^molecular_function^ATP binding,GO:0008017^molecular_function^microtubule binding,GO:0003777^molecular_function^microtubule motor activity,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,KEGG:mmu:68970`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4886_c0_g1_i2,DN4886_c0_g1,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,KEGG:hsa:121551`KO:K10483,ENOG410XRDX^BTB (POZ) domain containing,PF13606.6^Ank_3^Ankyrin repeat^290-318^E:1.9e-05,PF13637.6^Ank_4^Ankyrin repeats (many copies)^290-356^E:2.9e-08,PF00023.30^Ank^Ankyrin repeat^290-318^E:1.3e-06,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^335-401^E:1.4e-09,PF13606.6^Ank_3^Ankyrin repeat^375-400^E:0.00048,,
no,AD,DB,DN4886_c0_g1_i3,DN4886_c0_g1,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,KEGG:hsa:121551`KO:K10483,ENOG410XRDX^BTB (POZ) domain containing,PF13606.6^Ank_3^Ankyrin repeat^290-318^E:1.6e-05,PF00023.30^Ank^Ankyrin repeat^290-318^E:1.1e-06,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^335-401^E:1.3e-09,PF13606.6^Ank_3^Ankyrin repeat^375-400^E:0.00041,PF00023.30^Ank^Ankyrin repeat^376-402^E:0.021,,
no,AD,DB,DN21633_c0_g1_i5,DN21633_c0_g1,DBR1_CHICK,Lariat debranching enzyme,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",.,NA,NA,NA,NA,KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,.,NA,NA,NA,NA,,
no,AD,DB,DN21633_c0_g1_i6,DN21633_c0_g1,DBR1_CHICK,Lariat debranching enzyme,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008419^molecular_function^RNA lariat debranching enzyme activity,"GO:0000398^biological_process^mRNA splicing, via spliceosome","GO:0000375^biological_process^RNA splicing, via transesterification reactions",.,NA,NA,NA,NA,KEGG:gga:429118`KO:K18328,ENOG410XP0F^debranching enzyme,.,NA,NA,NA,NA,,
no,AD,DB,DN12578_c0_g1_i5,DN12578_c0_g1,DCA11_MOUSE,DDB1- and CUL4-associated factor 11,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:mmu:28199`KO:K11801,ENOG410XP4W^ddb1 and cul4 associated factor 11,.,NA,NA,NA,NA,,
no,AD,DB,DN12578_c0_g2_i2,DN12578_c0_g2,DCA11_PONAB,DDB1- and CUL4-associated factor 11,DCA11_RAT,DDB1- and CUL4-associated factor 11,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:rno:305895`KO:K11801,ENOG410XP4W^ddb1 and cul4 associated factor 11,"PF00400.32^WD40^WD domain, G-beta repeat^246-278^E:0.021","PF00400.32^WD40^WD domain, G-beta repeat^288-325^E:0.0011","PF00400.32^WD40^WD domain, G-beta repeat^415-449^E:6.4e-06",NA,NA,,
no,AD,DB,DN19897_c2_g1_i4,DN19897_c2_g1,RPB1_HUMAN,DNA-directed RNA polymerase II subunit RPB1,Y0266_DICDI,Uncharacterized protein DDB_G0290685,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0005665^cellular_component^RNA polymerase II, core complex",GO:0003677^molecular_function^DNA binding,GO:0099139^biological_process^cheating during chimeric sorocarp development,NA,NA,NA,NA,KEGG:hsa:5430`KO:K03006,COG0086^DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN19885_c0_g1_i2,DN19885_c0_g1,MANG_DICDI,Alpha-mannosidase G,.,NA,GO:0004559^molecular_function^alpha-mannosidase activity,GO:0030246^molecular_function^carbohydrate binding,GO:0046872^molecular_function^metal ion binding,GO:0006013^biological_process^mannose metabolic process,GO:0009313^biological_process^oligosaccharide catabolic process,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0287577`KO:K01191,COG0383^alpha-mannosidase,.,NA,NA,NA,NA,,
no,AD,DB,DN45106_c0_g1_i2,DN45106_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN45106_c0_g1_i1,DN45106_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN53387_c0_g1_i1,DN53387_c0_g1,PRP8_DICDI,Pre-mRNA-processing-splicing factor 8 homolog,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016607^cellular_component^nuclear speck,GO:0005682^cellular_component^U5 snRNP,GO:0097157^molecular_function^pre-mRNA intronic binding,GO:0000386^molecular_function^second spliceosomal transesterification activity,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0274229`KO:K12856,COG5178^PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN541_c1_g1_i9,DN541_c1_g1,Y0266_DICDI,Uncharacterized protein DDB_G0290685,.,NA,GO:0099139^biological_process^cheating during chimeric sorocarp development,NA,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i10,DN582_c0_g1,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,KEGG:hsa:5885`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04825.13^Rad21_Rec8_N^N terminus of Rad21 / Rec8 like protein^2-55^E:2.4e-17,PF04824.16^Rad21_Rec8^Conserved region of Rad21 / Rec8 like protein^529-582^E:3.2e-22,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i5,DN582_c0_g1,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,KEGG:bta:540966`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04825.13^Rad21_Rec8_N^N terminus of Rad21 / Rec8 like protein^1-92^E:2.8e-40,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i2,DN582_c0_g1,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,KEGG:bta:540966`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04824.16^Rad21_Rec8^Conserved region of Rad21 / Rec8 like protein^122-175^E:4.9e-23,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i8,DN582_c0_g1,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,KEGG:hsa:5885`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04824.16^Rad21_Rec8^Conserved region of Rad21 / Rec8 like protein^97-150^E:3.6e-23,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i6,DN582_c0_g1,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,KEGG:hsa:5885`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04824.16^Rad21_Rec8^Conserved region of Rad21 / Rec8 like protein^413-466^E:2.4e-22,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i4,DN582_c0_g1,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,KEGG:bta:540966`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g1_i1,DN582_c0_g1,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,RAD21_BOVIN,Double-strand-break repair protein rad21 homolog,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,KEGG:bta:540966`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g2_i1,DN582_c0_g2,RAD21_MOUSE,Double-strand-break repair protein rad21 homolog,.,NA,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:mmu:19357`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g2_i2,DN582_c0_g2,RAD21_MOUSE,Double-strand-break repair protein rad21 homolog,.,NA,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:mmu:19357`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN582_c0_g3_i1,DN582_c0_g3,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,.,NA,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,.,NA,NA,NA,NA,KEGG:hsa:5885`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN2102_c1_g1_i9,DN2102_c1_g1,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,KEGG:hsa:57683,"ENOG410YJEQ^zinc finger, DBF-type containing 2",PF07535.12^zf-DBF^DBF zinc finger^54-82^E:1e-06,NA,NA,NA,NA,,
no,AD,DB,DN2102_c1_g1_i6,DN2102_c1_g1,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,KEGG:hsa:57683,"ENOG410YJEQ^zinc finger, DBF-type containing 2",PF07535.12^zf-DBF^DBF zinc finger^54-82^E:1.1e-06,NA,NA,NA,NA,,
no,AD,DB,DN2102_c1_g1_i8,DN2102_c1_g1,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,KEGG:hsa:57683,"ENOG410YJEQ^zinc finger, DBF-type containing 2",PF07535.12^zf-DBF^DBF zinc finger^54-82^E:1.1e-06,NA,NA,NA,NA,,
no,AD,DB,DN2102_c1_g1_i7,DN2102_c1_g1,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,KEGG:hsa:57683,"ENOG410YJEQ^zinc finger, DBF-type containing 2",PF07535.12^zf-DBF^DBF zinc finger^54-82^E:1.1e-06,NA,NA,NA,NA,,
no,AD,DB,DN2102_c1_g1_i5,DN2102_c1_g1,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,ZDBF2_HUMAN,DBF4-type zinc finger-containing protein 2,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0003676^molecular_function^nucleic acid binding,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,KEGG:hsa:57683,"ENOG410YJEQ^zinc finger, DBF-type containing 2",PF07535.12^zf-DBF^DBF zinc finger^54-82^E:1.1e-06,NA,NA,NA,NA,,
no,AD,DB,DN77990_c0_g1_i1,DN77990_c0_g1,RBM38_CHICK,RNA-binding protein 38,RBM38_CHICK,RNA-binding protein 38,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0003729^molecular_function^mRNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0003729^molecular_function^mRNA binding,KEGG:gga:768866,ENOG410YDBV^NA,.,NA,NA,NA,NA,,
no,AD,DB,DN1269_c0_g1_i4,DN1269_c0_g1,DBP_RAT,D site-binding protein,DBP_BOVIN,D site-binding protein,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0007623^biological_process^circadian rhythm,GO:0001889^biological_process^liver development,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0007623^biological_process^circadian rhythm,NA,KEGG:bta:503577`KO:K09056,ENOG410YAPB^D site of albumin promoter (albumin D-box) binding protein,PF07716.15^bZIP_2^Basic region leucine zipper^54-106^E:9e-14,NA,NA,NA,NA,,
no,AD,DB,DN7080_c0_g1_i3,DN7080_c0_g1,Y8948_DICDI,Putative methyltransferase DDB_G0268948,Y8948_DICDI,Putative methyltransferase DDB_G0268948,GO:0045335^cellular_component^phagocytic vesicle,GO:0008757^molecular_function^S-adenosylmethionine-dependent methyltransferase activity,NA,NA,NA,GO:0045335^cellular_component^phagocytic vesicle,GO:0008757^molecular_function^S-adenosylmethionine-dependent methyltransferase activity,NA,NA,NA,KEGG:ddi:DDB_G0268948,ENOG4111IQH^Methyltransferase,PF01209.18^Ubie_methyltran^ubiE/COQ5 methyltransferase family^79-214^E:8.9e-12,PF13489.6^Methyltransf_23^Methyltransferase domain^81-214^E:4.6e-07,PF08241.12^Methyltransf_11^Methyltransferase domain^85-176^E:1.9e-23,PF13649.6^Methyltransf_25^Methyltransferase domain^85-173^E:3.2e-21,PF13847.6^Methyltransf_31^Methyltransferase domain^85-193^E:3.1e-15,,
no,AD,DB,DN7080_c0_g1_i2,DN7080_c0_g1,Y8948_DICDI,Putative methyltransferase DDB_G0268948,Y8948_DICDI,Putative methyltransferase DDB_G0268948,GO:0045335^cellular_component^phagocytic vesicle,GO:0008757^molecular_function^S-adenosylmethionine-dependent methyltransferase activity,NA,NA,NA,GO:0045335^cellular_component^phagocytic vesicle,GO:0008757^molecular_function^S-adenosylmethionine-dependent methyltransferase activity,NA,NA,NA,KEGG:ddi:DDB_G0268948,ENOG4111IQH^Methyltransferase,PF01209.18^Ubie_methyltran^ubiE/COQ5 methyltransferase family^79-215^E:6.9e-12,PF13489.6^Methyltransf_23^Methyltransferase domain^81-225^E:3.6e-07,PF08241.12^Methyltransf_11^Methyltransferase domain^85-176^E:1.6e-23,PF13649.6^Methyltransf_25^Methyltransferase domain^85-173^E:2.7e-21,PF13847.6^Methyltransf_31^Methyltransferase domain^85-193^E:2.5e-15,,
no,AD,DB,DN84246_c0_g1_i4,DN84246_c0_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN84246_c0_g1_i2,DN84246_c0_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},.,NA,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,.,NA,NA,NA,NA,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN84246_c0_g1_i1,DN84246_c0_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN84246_c1_g1_i5,DN84246_c1_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},.,NA,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,.,NA,NA,NA,NA,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN84246_c1_g1_i2,DN84246_c1_g1,CRNS1_CHICK,Carnosine synthase 1 {ECO:0000312|EMBL:ADB91406.1},.,NA,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0047730^molecular_function^carnosine synthase activity,GO:0010181^molecular_function^FMN binding,GO:0102102^molecular_function^homocarnosine synthase activity,.,NA,NA,NA,NA,KEGG:gga:100359387`KO:K14755,.,.,NA,NA,NA,NA,,
no,AD,DB,DN908_c7_g1_i3,DN908_c7_g1,EEDB_XENLA,Polycomb protein eed-B,.,NA,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0016571^biological_process^histone methylation,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xla:398420`KO:K11462,.,.,NA,NA,NA,NA,,
no,AD,DB,DN99905_c0_g1_i1,DN99905_c0_g1,CFAD_DICDI,Counting factor associated protein D,CFAD_DICDI,Counting factor associated protein D,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005764^cellular_component^lysosome,GO:0004197^molecular_function^cysteine-type endopeptidase activity,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005764^cellular_component^lysosome,GO:0004197^molecular_function^cysteine-type endopeptidase activity,KEGG:ddi:DDB_G0281605,COG4870^cathepsin,PF08246.12^Inhibitor_I29^Cathepsin propeptide inhibitor domain (I29)^78-128^E:1.6e-09,NA,NA,NA,NA,,
no,AD,DB,DN65482_c0_g1_i1,DN65482_c0_g1,MOXD2_HUMAN,Putative DBH-like monooxygenase protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0030667^cellular_component^secretory granule membrane,GO:0005507^molecular_function^copper ion binding,GO:0004500^molecular_function^dopamine beta-monooxygenase activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,DB,DN14831_c0_g1_i1,DN14831_c0_g1,DAL1A_XENLA,Death-associated protein-like 1-A,DAPL1_MOUSE,Death-associated protein-like 1,.,NA,NA,NA,NA,GO:0070513^molecular_function^death domain binding,GO:0097190^biological_process^apoptotic signaling pathway,GO:0030154^biological_process^cell differentiation,GO:0034198^biological_process^cellular response to amino acid starvation,GO:0010507^biological_process^negative regulation of autophagy,KEGG:mmu:76747,ENOG4112DBS^death associated protein-like 1,PF15228.6^DAP^Death-associated protein^32-124^E:8.6e-27,NA,NA,NA,NA,,
no,AD,DB,DN2415_c0_g3_i2,DN2415_c0_g3,DCA12_DANRE,DDB1- and CUL4-associated factor 12,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005815^cellular_component^microtubule organizing center,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:dre:570671`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN55513_c0_g1_i2,DN55513_c0_g1,DP87_DICDI,Prespore protein Dp87,DP87_DICDI,Prespore protein Dp87,GO:0031160^cellular_component^spore wall,GO:0030435^biological_process^sporulation resulting in formation of a cellular spore,NA,NA,NA,GO:0031160^cellular_component^spore wall,GO:0030435^biological_process^sporulation resulting in formation of a cellular spore,NA,NA,NA,KEGG:ddi:DDB_G0283149,ENOG410YUQP^FOLN,.,NA,NA,NA,NA,,
no,AD,DB,DN55513_c0_g1_i5,DN55513_c0_g1,DP87_DICDI,Prespore protein Dp87,DP87_DICDI,Prespore protein Dp87,GO:0031160^cellular_component^spore wall,GO:0030435^biological_process^sporulation resulting in formation of a cellular spore,NA,NA,NA,GO:0031160^cellular_component^spore wall,GO:0030435^biological_process^sporulation resulting in formation of a cellular spore,NA,NA,NA,KEGG:ddi:DDB_G0283149,ENOG410YUQP^FOLN,.,NA,NA,NA,NA,,
no,AD,DB,DN96392_c0_g1_i1,DN96392_c0_g1,DLRB2_BOVIN,Dynein light chain roadblock-type 2,DLRB2_BOVIN,Dynein light chain roadblock-type 2,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005874^cellular_component^microtubule,GO:0045505^molecular_function^dynein intermediate chain binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005874^cellular_component^microtubule,GO:0045505^molecular_function^dynein intermediate chain binding,KEGG:bta:768062`KO:K10419,"ENOG4111NDV^dynein, light chain",PF03259.17^Robl_LC7^Roadblock/LC7 domain^34-121^E:3.4e-24,NA,NA,NA,NA,,
no,AD,DB,DN96392_c0_g1_i7,DN96392_c0_g1,DLRB2_BOVIN,Dynein light chain roadblock-type 2,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005874^cellular_component^microtubule,GO:0045505^molecular_function^dynein intermediate chain binding,.,NA,NA,NA,NA,KEGG:bta:768062`KO:K10419,"ENOG4111NDV^dynein, light chain",.,NA,NA,NA,NA,,
no,AD,DB,DN96392_c0_g1_i3,DN96392_c0_g1,DLRB2_BOVIN,Dynein light chain roadblock-type 2,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005874^cellular_component^microtubule,GO:0045505^molecular_function^dynein intermediate chain binding,.,NA,NA,NA,NA,KEGG:bta:768062`KO:K10419,"ENOG4111NDV^dynein, light chain",.,NA,NA,NA,NA,,
no,AD,DB,DN96392_c0_g1_i6,DN96392_c0_g1,DLRB2_BOVIN,Dynein light chain roadblock-type 2,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005868^cellular_component^cytoplasmic dynein complex,GO:0005874^cellular_component^microtubule,GO:0045505^molecular_function^dynein intermediate chain binding,.,NA,NA,NA,NA,KEGG:bta:768062`KO:K10419,"ENOG4111NDV^dynein, light chain",.,NA,NA,NA,NA,,
no,AD,DB,DN6492_c0_g1_i1,DN6492_c0_g1,HS7C1_DICDI,Heat shock cognate 70 kDa protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031012^cellular_component^extracellular matrix,GO:0005811^cellular_component^lipid droplet,GO:0045335^cellular_component^phagocytic vesicle,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0269144`KO:K03283,COG0443^Heat shock protein,.,NA,NA,NA,NA,,
no,AD,DB,DN36726_c0_g1_i13,DN36726_c0_g1,REC8_HUMAN,Meiotic recombination protein REC8 homolog,.,NA,GO:0000778^cellular_component^condensed nuclear chromosome kinetochore,GO:0000800^cellular_component^lateral element,GO:0001673^cellular_component^male germ cell nucleus,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:9985`KO:K13054,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN36726_c0_g1_i15,DN36726_c0_g1,REC8_HUMAN,Meiotic recombination protein REC8 homolog,REC8_HUMAN,Meiotic recombination protein REC8 homolog,GO:0000778^cellular_component^condensed nuclear chromosome kinetochore,GO:0000800^cellular_component^lateral element,GO:0001673^cellular_component^male germ cell nucleus,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0000778^cellular_component^condensed nuclear chromosome kinetochore,GO:0000800^cellular_component^lateral element,GO:0001673^cellular_component^male germ cell nucleus,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,KEGG:hsa:9985`KO:K13054,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04825.13^Rad21_Rec8_N^N terminus of Rad21 / Rec8 like protein^6-46^E:0.00014,NA,NA,NA,NA,,
no,AD,DB,DN36726_c0_g1_i7,DN36726_c0_g1,.,NA,REC8_RAT,Meiotic recombination protein REC8 homolog,.,NA,NA,NA,NA,GO:0000778^cellular_component^condensed nuclear chromosome kinetochore,GO:0000800^cellular_component^lateral element,GO:0001673^cellular_component^male germ cell nucleus,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,KEGG:rno:290227`KO:K13054,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN11325_c0_g1_i1,DN11325_c0_g1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,.,ENOG4110DBH^regulation of mitochondrial membrane permeability involved in apoptotic process,PF13873.6^Myb_DNA-bind_5^Myb/SANT-like DNA-binding domain^12-89^E:9.5e-26,PF10545.9^MADF_DNA_bdg^Alcohol dehydrogenase transcription factor Myb/SANT-like^47-93^E:9.8e-05,NA,NA,NA,,
no,AD,DB,DN11325_c0_g2_i1,DN11325_c0_g2,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,NAIF1_CHICK,Nuclear apoptosis-inducing factor 1,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,GO:0000801^cellular_component^central element,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0010705^biological_process^meiotic DNA double-strand break processing involved in reciprocal meiotic recombination,GO:0048477^biological_process^oogenesis,.,ENOG4110DBH^regulation of mitochondrial membrane permeability involved in apoptotic process,PF13873.6^Myb_DNA-bind_5^Myb/SANT-like DNA-binding domain^13-90^E:1.3e-25,PF10545.9^MADF_DNA_bdg^Alcohol dehydrogenase transcription factor Myb/SANT-like^48-94^E:0.00013,NA,NA,NA,,
no,AD,DB,DN10578_c0_g2_i2,DN10578_c0_g2,DBLOH_MOUSE,"Diablo homolog, mitochondrial",.,NA,GO:0035631^cellular_component^CD40 receptor complex,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005758^cellular_component^mitochondrial intermembrane space,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:66593`KO:K10522,"ENOG4111KJ0^Diablo, IAP-binding mitochondrial protein",.,NA,NA,NA,NA,,
no,AD,DB,DN10515_c1_g1_i1,DN10515_c1_g1,GRWD1_RAT,Glutamate-rich WD repeat-containing protein 1,GRWD1_HUMAN,Glutamate-rich WD repeat-containing protein 1,GO:0005694^cellular_component^chromosome,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0003688^molecular_function^DNA replication origin binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:83743`KO:K14848,ENOG410XPDB^Glutamate-rich wd repeat-containing protein,PF12265.8^CAF1C_H4-bd^Histone-binding protein RBBP4 or subunit C of CAF1 complex^55-122^E:1.9e-10,NA,NA,NA,NA,,
no,AD,DB,DN1869_c1_g1_i3,DN1869_c1_g1,DDB1_CHICK,DNA damage-binding protein 1,DDB1_CHICK,DNA damage-binding protein 1,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,KEGG:gga:374050`KO:K10610,ENOG410XPF6^DNA- binding protein,PF10433.9^MMS1_N^Mono-functional DNA-alkylating methyl methanesulfonate N-term^75-543^E:4.2e-118,PF03178.15^CPSF_A^CPSF A subunit region^791-1099^E:1e-83,NA,NA,NA,,
no,AD,DB,DN1869_c1_g1_i1,DN1869_c1_g1,DDB1_CHICK,DNA damage-binding protein 1,DDB1_CHICK,DNA damage-binding protein 1,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,KEGG:gga:374050`KO:K10610,ENOG410XPF6^DNA- binding protein,PF10433.9^MMS1_N^Mono-functional DNA-alkylating methyl methanesulfonate N-term^75-543^E:3.8e-118,PF03178.15^CPSF_A^CPSF A subunit region^791-1075^E:2.6e-75,NA,NA,NA,,
no,AD,DB,DN8645_c0_g1_i6,DN8645_c0_g1,SSBP3_RAT,Single-stranded DNA-binding protein 3,SSBP3_RAT,Single-stranded DNA-binding protein 3,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0060322^biological_process^head development,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0060322^biological_process^head development,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,KEGG:rno:84354,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^123-164^E:4.9e-16","PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^164-380^E:1.5e-63",NA,NA,NA,,
no,AD,DB,DN8645_c0_g1_i5,DN8645_c0_g1,SSBP3_MOUSE,Single-stranded DNA-binding protein 3,SSBP3_MOUSE,Single-stranded DNA-binding protein 3,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,KEGG:mmu:72475,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^1-223^E:9.2e-68",NA,NA,NA,NA,,
no,AD,DB,DN8645_c0_g1_i10,DN8645_c0_g1,SSBP3_MOUSE,Single-stranded DNA-binding protein 3,SSBP3_MOUSE,Single-stranded DNA-binding protein 3,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,KEGG:mmu:72475,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^123-407^E:1.7e-97",NA,NA,NA,NA,,
no,AD,DB,DN49647_c0_g1_i2,DN49647_c0_g1,PCDB1_HUMAN,Protocadherin beta-1,PCDB1_HUMAN,Protocadherin beta-1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:hsa:29930`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN49647_c0_g2_i1,DN49647_c0_g2,PCDBF_PANTR,Protocadherin beta-15,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN1090_c0_g1_i16,DN1090_c0_g1,CLC2D_HUMAN,C-type lectin domain family 2 member D,CL2DB_RAT,C-type lectin domain family 2 member D11,GO:0009986^cellular_component^cell surface,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,KEGG:rno:362447,ENOG410XPJ1^c-type lectin domain family,PF00059.21^Lectin_C^Lectin C-type domain^74-133^E:3.7e-08,NA,NA,NA,NA,,
no,AD,DB,DN1090_c0_g1_i2,DN1090_c0_g1,CL2DB_RAT,C-type lectin domain family 2 member D11,CLC2D_MOUSE,C-type lectin domain family 2 member D,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030246^molecular_function^carbohydrate binding,GO:0046703^molecular_function^natural killer cell lectin-like receptor binding,GO:0004888^molecular_function^transmembrane signaling receptor activity,KEGG:mmu:93694,ENOG410XPJ1^c-type lectin domain family,PF00059.21^Lectin_C^Lectin C-type domain^74-135^E:1.8e-08,NA,NA,NA,NA,,
no,AD,DB,DN24239_c0_g1_i2,DN24239_c0_g1,RD21L_HUMAN,Double-strand-break repair protein rad21-like protein 1,RD21L_HUMAN,Double-strand-break repair protein rad21-like protein 1,GO:0005694^cellular_component^chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0005634^cellular_component^nucleus,GO:0005694^cellular_component^chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0005634^cellular_component^nucleus,KEGG:hsa:642636,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN24239_c0_g1_i1,DN24239_c0_g1,RD21L_HUMAN,Double-strand-break repair protein rad21-like protein 1,RD21L_HUMAN,Double-strand-break repair protein rad21-like protein 1,GO:0005694^cellular_component^chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0005634^cellular_component^nucleus,GO:0005694^cellular_component^chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,GO:0005634^cellular_component^nucleus,KEGG:hsa:642636,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN361_c0_g1_i4,DN361_c0_g1,TTMP_HUMAN,TPA-induced transmembrane protein,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:79669,ENOG410ZDDB^chromosome 3 open reading frame 52,.,NA,NA,NA,NA,,
no,AD,DB,DN361_c0_g1_i5,DN361_c0_g1,TTMP_HUMAN,TPA-induced transmembrane protein,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:79669,ENOG410ZDDB^chromosome 3 open reading frame 52,.,NA,NA,NA,NA,,
no,AD,DB,DN361_c0_g1_i7,DN361_c0_g1,TTMP_HUMAN,TPA-induced transmembrane protein,TTMP_HUMAN,TPA-induced transmembrane protein,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,KEGG:hsa:79669,ENOG410ZDDB^chromosome 3 open reading frame 52,.,NA,NA,NA,NA,,
no,AD,DB,DN361_c0_g1_i2,DN361_c0_g1,TTMP_HUMAN,TPA-induced transmembrane protein,TTMP_HUMAN,TPA-induced transmembrane protein,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,KEGG:hsa:79669,ENOG410ZDDB^chromosome 3 open reading frame 52,PF01390.20^SEA^SEA domain^40-86^E:2.7e-05,NA,NA,NA,NA,,
no,AD,DB,DN83176_c0_g1_i3,DN83176_c0_g1,DCAF5_MOUSE,DDB1- and CUL4-associated factor 5,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005739^cellular_component^mitochondrion,GO:0016567^biological_process^protein ubiquitination,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:320808`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,.,NA,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i6,DN4950_c0_g1,LDB2_HUMAN,LIM domain-binding protein 2,LDB2_HUMAN,LIM domain-binding protein 2,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,KEGG:hsa:9079,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:3.2e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:9.7e-12,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i1,DN4950_c0_g1,LDB2_CHICK,LIM domain-binding protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:gga:395631,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i7,DN4950_c0_g1,LDB2_HUMAN,LIM domain-binding protein 2,LDB2_HUMAN,LIM domain-binding protein 2,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,KEGG:hsa:9079,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:4.5e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:1.2e-11,PF17916.1^LID^LIM interaction domain (LID)^297-325^E:3.2e-18,NA,NA,,
no,AD,DB,DN4950_c0_g1_i3,DN4950_c0_g1,LDB2_CHICK,LIM domain-binding protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:gga:395631,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i8,DN4950_c0_g1,LDB2_HUMAN,LIM domain-binding protein 2,LDB2_CHICK,LIM domain-binding protein 2,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,KEGG:gga:395631,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:3.4e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:1e-11,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i2,DN4950_c0_g1,LDB2_CHICK,LIM domain-binding protein 2,LDB2_CHICK,LIM domain-binding protein 2,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,GO:0003712^molecular_function^transcription coregulator activity,KEGG:gga:395631,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:4.5e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:1.2e-11,PF17916.1^LID^LIM interaction domain (LID)^296-324^E:3.2e-18,NA,NA,,
no,AD,DB,DN4950_c0_g1_i4,DN4950_c0_g1,LDB2_HUMAN,LIM domain-binding protein 2,LDB2_HUMAN,LIM domain-binding protein 2,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,KEGG:hsa:9079,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:2.7e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:8.8e-12,NA,NA,NA,,
no,AD,DB,DN4950_c0_g1_i5,DN4950_c0_g1,LDB2_HUMAN,LIM domain-binding protein 2,LDB2_HUMAN,LIM domain-binding protein 2,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,GO:0031252^cellular_component^cell leading edge,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0005667^cellular_component^transcription factor complex,KEGG:hsa:9079,ENOG410YZVH^Lim domain binding,PF01803.16^LIM_bind^LIM-domain binding protein^30-179^E:3.4e-44,PF01803.16^LIM_bind^LIM-domain binding protein^183-232^E:1e-11,NA,NA,NA,,
no,AD,DB,DN4982_c0_g1_i6,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,PF00856.28^SET^SET domain^48-142^E:2.3e-17,NA,NA,NA,NA,,
no,AD,DB,DN4982_c0_g1_i1,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,PF01429.19^MBD^Methyl-CpG binding domain^190-233^E:2.5e-08,PF05033.16^Pre-SET^Pre-SET motif^251-365^E:1.1e-14,PF00856.28^SET^SET domain^384-474^E:1.2e-05,NA,NA,,
no,AD,DB,DN4982_c0_g1_i2,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,PF01429.19^MBD^Methyl-CpG binding domain^190-233^E:2.1e-08,PF05033.16^Pre-SET^Pre-SET motif^251-365^E:9.3e-15,PF00856.28^SET^SET domain^384-447^E:2.7e-05,NA,NA,,
no,AD,DB,DN4982_c0_g1_i7,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,PF00856.28^SET^SET domain^130-292^E:1e-16,NA,NA,NA,NA,,
no,AD,DB,DN4982_c0_g1_i5,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,PF01429.19^MBD^Methyl-CpG binding domain^190-233^E:1.7e-08,PF05033.16^Pre-SET^Pre-SET motif^251-365^E:6.9e-15,NA,NA,NA,,
no,AD,DB,DN4982_c0_g1_i4,DN4982_c0_g1,SETB2_HUMAN,Histone-lysine N-methyltransferase SETDB2,.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:hsa:83852`KO:K18494,COG2940^Histone-lysine N-methyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN5069_c0_g1_i5,DN5069_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN5069_c0_g1_i3,DN5069_c0_g1,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN5069_c0_g2_i1,DN5069_c0_g2,ODBA_HUMAN,"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:593`KO:K00166,COG1071^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i16,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,DDB2_CHICK,DNA damage-binding protein 2,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa","PF00400.32^WD40^WD domain, G-beta repeat^73-110^E:0.00037",NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i6,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i5,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,DDB2_CHICK,DNA damage-binding protein 2,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa","PF00400.32^WD40^WD domain, G-beta repeat^89-126^E:0.00039",NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i4,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i11,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i14,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,DDB2_CHICK,DNA damage-binding protein 2,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa","PF00400.32^WD40^WD domain, G-beta repeat^73-110^E:0.00037",NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i2,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,DDB2_CHICK,DNA damage-binding protein 2,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa","PF00400.32^WD40^WD domain, G-beta repeat^73-110^E:0.00037",NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i3,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i9,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g1_i7,DN742_c0_g1,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN742_c0_g2_i1,DN742_c0_g2,DDB2_CHICK,DNA damage-binding protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003684^molecular_function^damaged DNA binding,.,NA,NA,NA,NA,KEGG:gga:423185`KO:K10140,"ENOG410ZSSH^Damage-specific DNA binding protein 2, 48kDa",.,NA,NA,NA,NA,,
no,AD,DB,DN72432_c0_g1_i1,DN72432_c0_g1,LDB1_XENLA,LIM domain-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:xla:380241`KEGG:xla:779363`KO:K15617,.,.,NA,NA,NA,NA,,
no,AD,DB,DN9898_c0_g1_i3,DN9898_c0_g1,SSBP3_RAT,Single-stranded DNA-binding protein 3,SSBP4_HUMAN,Single-stranded DNA-binding protein 4,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0060322^biological_process^head development,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,NA,KEGG:hsa:170463,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^81-122^E:1.4e-15","PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^122-336^E:2.8e-64",NA,NA,NA,,
no,AD,DB,DN9898_c0_g1_i2,DN9898_c0_g1,SSBP3_MOUSE,Single-stranded DNA-binding protein 3,SSBP4_HUMAN,Single-stranded DNA-binding protein 4,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,NA,KEGG:hsa:170463,ENOG410XPQX^midbrain-hindbrain boundary initiation,"PF04503.13^SSDP^Single-stranded DNA binding protein, SSDP^81-364^E:1.2e-95",NA,NA,NA,NA,,
no,AD,DB,DN2222_c1_g1_i2,DN2222_c1_g1,F83DB_XENLA,Protein FAM83D-B {ECO:0000305},FA83D_HUMAN,Protein FAM83D {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0019894^molecular_function^kinesin binding,GO:0008017^molecular_function^microtubule binding,GO:0019901^molecular_function^protein kinase binding,KEGG:hsa:81610`KO:K16805,"ENOG410ZYBU^family with sequence similarity 83, member D",PF07894.12^FAM83^FAM83 A-H^1-135^E:2.1e-57,PF13091.6^PLDc_2^PLD-like domain^2-127^E:1.1e-06,NA,NA,NA,,
no,AD,DB,DN2222_c1_g1_i4,DN2222_c1_g1,F83DB_XENLA,Protein FAM83D-B {ECO:0000305},F83DB_XENLA,Protein FAM83D-B {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,KEGG:xla:495259`KO:K16805,.,PF07894.12^FAM83^FAM83 A-H^22-284^E:1.8e-96,PF13091.6^PLDc_2^PLD-like domain^142-276^E:7.6e-09,NA,NA,NA,,
no,AD,DB,DN2222_c1_g2_i1,DN2222_c1_g2,FA83D_HUMAN,Protein FAM83D {ECO:0000305},F83DB_XENLA,Protein FAM83D-B {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0019894^molecular_function^kinesin binding,GO:0008017^molecular_function^microtubule binding,GO:0019901^molecular_function^protein kinase binding,GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,KEGG:xla:495259`KO:K16805,"ENOG410ZYBU^family with sequence similarity 83, member D",PF07894.12^FAM83^FAM83 A-H^22-284^E:8.1e-98,PF13091.6^PLDc_2^PLD-like domain^142-275^E:4.3e-09,NA,NA,NA,,
no,AD,DB,DN1373_c0_g1_i8,DN1373_c0_g1,ABHDB_HUMAN,Protein ABHD11 {ECO:0000305},.,NA,GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:83451`KO:K13703,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,DB,DN1373_c0_g1_i11,DN1373_c0_g1,ABHDB_DANRE,Protein ABHD11 {ECO:0000305},ABHDB_DANRE,Protein ABHD11 {ECO:0000305},GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,KEGG:dre:446169`KO:K13703,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,DB,DN1373_c0_g1_i2,DN1373_c0_g1,ABHDB_XENTR,Protein ABHD11 {ECO:0000305},ABHDB_XENTR,Protein ABHD11 {ECO:0000305},GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,KEGG:xtr:779475`KO:K13703,COG0596^Alpha beta hydrolase,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^108-206^E:1.3e-12",PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^110-227^E:1.8e-21,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^112-290^E:1.4e-12,NA,NA,,
no,AD,DB,DN1373_c0_g1_i5,DN1373_c0_g1,ABHDB_DANRE,Protein ABHD11 {ECO:0000305},ABHDB_XENTR,Protein ABHD11 {ECO:0000305},GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,KEGG:xtr:779475`KO:K13703,COG0596^Alpha beta hydrolase,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^108-197^E:4.9e-11",PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^110-196^E:2.1e-17,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^112-196^E:1.7e-10,NA,NA,,
no,AD,DB,DN1373_c0_g1_i4,DN1373_c0_g1,ABHDB_XENTR,Protein ABHD11 {ECO:0000305},.,NA,GO:0005739^cellular_component^mitochondrion,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xtr:779475`KO:K13703,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,DB,DN70009_c0_g1_i1,DN70009_c0_g1,ODB2_MOUSE,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0016407^molecular_function^acetyltransferase activity,GO:0043754^molecular_function^dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,.,NA,NA,NA,NA,KEGG:mmu:13171`KO:K09699,COG0508^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN70009_c2_g1_i1,DN70009_c2_g1,ODB2_HUMAN,"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:1629`KO:K09699,COG0508^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DB,DN7188_c0_g2_i3,DN7188_c0_g2,CYSP2_HOMAM,Digestive cysteine proteinase 2,CFAD_DICDI,Counting factor associated protein D,GO:0008234^molecular_function^cysteine-type peptidase activity,NA,NA,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005764^cellular_component^lysosome,GO:0004197^molecular_function^cysteine-type endopeptidase activity,KEGG:ddi:DDB_G0281605,COG4870^cathepsin,PF00112.23^Peptidase_C1^Papain family cysteine protease^3-113^E:1.3e-35,NA,NA,NA,NA,,
no,AD,DB,DN10172_c0_g1_i1,DN10172_c0_g1,F168B_RAT,Myelin-associated neurite-outgrowth inhibitor,F168B_HUMAN,Myelin-associated neurite-outgrowth inhibitor,GO:0030424^cellular_component^axon,GO:0016021^cellular_component^integral component of membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,NA,GO:0030424^cellular_component^axon,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:130074,"ENOG410YDBT^Family with sequence similarity 168, member B",PF14944.6^TCRP1^Tongue Cancer Chemotherapy Resistant Protein 1^31-82^E:1.4e-21,PF14944.6^TCRP1^Tongue Cancer Chemotherapy Resistant Protein 1^82-225^E:7.2e-87,NA,NA,NA,,
no,AD,DB,DN94484_c0_g1_i1,DN94484_c0_g1,RAD21_HUMAN,Double-strand-break repair protein rad21 homolog,.,NA,GO:0000785^cellular_component^chromatin,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000794^cellular_component^condensed nuclear chromosome,.,NA,NA,NA,NA,KEGG:hsa:5885`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN5350_c0_g1_i8,DN5350_c0_g1,DBF4B_HUMAN,Protein DBF4 homolog B,DBF4B_HUMAN,Protein DBF4 homolog B,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80174,COG5067^DBF4 homolog (S. cerevisiae),PF07535.12^zf-DBF^DBF zinc finger^261-305^E:1.5e-17,NA,NA,NA,NA,,
no,AD,DB,DN5350_c0_g1_i7,DN5350_c0_g1,DBF4B_HUMAN,Protein DBF4 homolog B,DBF4B_HUMAN,Protein DBF4 homolog B,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80174,COG5067^DBF4 homolog (S. cerevisiae),PF07535.12^zf-DBF^DBF zinc finger^19-63^E:9.4e-18,NA,NA,NA,NA,,
no,AD,DB,DN5350_c0_g1_i1,DN5350_c0_g1,DBF4B_HUMAN,Protein DBF4 homolog B,DBF4B_HUMAN,Protein DBF4 homolog B,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80174,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN5350_c0_g1_i6,DN5350_c0_g1,DBF4B_HUMAN,Protein DBF4 homolog B,DBF4B_HUMAN,Protein DBF4 homolog B,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80174,COG5067^DBF4 homolog (S. cerevisiae),.,NA,NA,NA,NA,,
no,AD,DB,DN5350_c0_g1_i9,DN5350_c0_g1,DBF4B_HUMAN,Protein DBF4 homolog B,DBF4B_HUMAN,Protein DBF4 homolog B,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0031431^cellular_component^Dbf4-dependent protein kinase complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:80174,COG5067^DBF4 homolog (S. cerevisiae),PF07535.12^zf-DBF^DBF zinc finger^114-158^E:1.2e-17,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i5,DN25752_c0_g1,PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,KEGG:ptr:462130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^49-140^E:7.4e-20,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i2,DN25752_c0_g1,PCDBF_PANTR,Protocadherin beta-15,PCDBF_PANTR,Protocadherin beta-15,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^22-113^E:4.3e-21,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i12,DN25752_c0_g1,PCDB8_PANTR,Protocadherin beta-8 {ECO:0000305},PCDBF_PANTR,Protocadherin beta-15,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^49-140^E:1.9e-20,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i8,DN25752_c0_g1,PCDBF_PANTR,Protocadherin beta-15,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i11,DN25752_c0_g1,PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,KEGG:ptr:462130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^51-140^E:1.6e-17,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i1,DN25752_c0_g1,PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},PCDB6_PANTR,Protocadherin beta-6 {ECO:0000305},GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0007155^biological_process^cell adhesion,GO:0009988^biological_process^cell-cell recognition,KEGG:ptr:462130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^51-140^E:1.3e-18,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i7,DN25752_c0_g1,PCDBF_PANTR,Protocadherin beta-15,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i4,DN25752_c0_g1,PCDBF_PANTR,Protocadherin beta-15,PCDBF_PANTR,Protocadherin beta-15,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^49-127^E:3.9e-19,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i6,DN25752_c0_g1,PCDBF_PANTR,Protocadherin beta-15,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g1_i3,DN25752_c0_g1,PCDB6_HUMAN,Protocadherin beta-6 {ECO:0000305},PCDB6_HUMAN,Protocadherin beta-6 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0016339^biological_process^calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0042802^molecular_function^identical protein binding,GO:0016339^biological_process^calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,KEGG:hsa:56130`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^51-127^E:3e-17,NA,NA,NA,NA,,
no,AD,DB,DN25752_c0_g2_i1,DN25752_c0_g2,PCDBF_PANTR,Protocadherin beta-15,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,.,NA,NA,NA,NA,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i1,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^44-75^E:0.01","PF00400.32^WD40^WD domain, G-beta repeat^749-777^E:0.037",NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i8,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i16,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i14,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^44-75^E:0.01","PF00400.32^WD40^WD domain, G-beta repeat^758-786^E:0.038",NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i3,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i4,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i9,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_PONAB,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:pon:100172900`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^44-75^E:0.01","PF00400.32^WD40^WD domain, G-beta repeat^769-797^E:0.038",NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i13,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_PONAB,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:pon:100172900`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^172-207^E:0.3","PF00400.32^WD40^WD domain, G-beta repeat^221-249^E:0.011",NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i11,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^44-75^E:0.01","PF00400.32^WD40^WD domain, G-beta repeat^758-786^E:0.038",NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i2,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN4480_c0_g1_i5,DN4480_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,"PF00400.32^WD40^WD domain, G-beta repeat^296-324^E:0.014",NA,NA,NA,NA,,
no,AD,DB,DN24910_c0_g1_i11,DN24910_c0_g1,MYOM_DICDI,Myosin-M heavy chain,MYOM_DICDI,Myosin-M heavy chain,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0016461^cellular_component^unconventional myosin complex,GO:0051015^molecular_function^actin filament binding,GO:0005524^molecular_function^ATP binding,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0016461^cellular_component^unconventional myosin complex,GO:0051015^molecular_function^actin filament binding,GO:0005524^molecular_function^ATP binding,KEGG:ddi:DDB_G0292262,COG5022^myosin heavy chain`COG5422^guanine nucleotide exchange factor,PF00621.20^RhoGEF^RhoGEF domain^305-488^E:4.4e-37,NA,NA,NA,NA,,
no,AD,DB,DN24910_c0_g1_i5,DN24910_c0_g1,MYOM_DICDI,Myosin-M heavy chain,MYOM_DICDI,Myosin-M heavy chain,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0016461^cellular_component^unconventional myosin complex,GO:0051015^molecular_function^actin filament binding,GO:0005524^molecular_function^ATP binding,GO:0042995^cellular_component^cell projection,GO:0005737^cellular_component^cytoplasm,GO:0016461^cellular_component^unconventional myosin complex,GO:0051015^molecular_function^actin filament binding,GO:0005524^molecular_function^ATP binding,KEGG:ddi:DDB_G0292262,COG5022^myosin heavy chain`COG5422^guanine nucleotide exchange factor,PF00621.20^RhoGEF^RhoGEF domain^782-965^E:1.1e-36,NA,NA,NA,NA,,
no,AD,DB,DN1643_c0_g2_i1,DN1643_c0_g2,.,NA,Y0266_DICDI,Uncharacterized protein DDB_G0290685,.,NA,NA,NA,NA,GO:0099139^biological_process^cheating during chimeric sorocarp development,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,DB,DN8426_c0_g1_i2,DN8426_c0_g1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,KEGG:hsa:54206,ENOG4111HB5^ERBB receptor feedback inhibitor 1,PF11555.8^Inhibitor_Mig-6^EGFR receptor inhibitor Mig-6^185-239^E:1e-14,NA,NA,NA,NA,,
no,AD,DB,DN8426_c0_g1_i3,DN8426_c0_g1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,KEGG:hsa:54206,ENOG4111HB5^ERBB receptor feedback inhibitor 1,PF11555.8^Inhibitor_Mig-6^EGFR receptor inhibitor Mig-6^252-306^E:1.3e-14,NA,NA,NA,NA,,
no,AD,DB,DN8426_c0_g1_i5,DN8426_c0_g1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,KEGG:hsa:54206,ENOG4111HB5^ERBB receptor feedback inhibitor 1,PF11555.8^Inhibitor_Mig-6^EGFR receptor inhibitor Mig-6^318-372^E:1.7e-14,NA,NA,NA,NA,,
no,AD,DB,DN8426_c0_g1_i1,DN8426_c0_g1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,ERRFI_HUMAN,ERBB receptor feedback inhibitor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005096^molecular_function^GTPase activator activity,KEGG:hsa:54206,ENOG4111HB5^ERBB receptor feedback inhibitor 1,PF11555.8^Inhibitor_Mig-6^EGFR receptor inhibitor Mig-6^304-358^E:1.6e-14,NA,NA,NA,NA,,
no,AD,DB,DN8426_c0_g3_i1,DN8426_c0_g3,ERRFI_MOUSE,ERBB receptor feedback inhibitor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:mmu:74155,ENOG4111HB5^ERBB receptor feedback inhibitor 1,.,NA,NA,NA,NA,,
no,AD,DB,DN13258_c0_g2_i1,DN13258_c0_g2,AASD1_RAT,Alanyl-tRNA editing protein Aarsd1,AASDB_XENLA,Alanyl-tRNA editing protein Aarsd1-B,GO:0005737^cellular_component^cytoplasm,GO:0004813^molecular_function^alanine-tRNA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,GO:0005737^cellular_component^cytoplasm,GO:0004813^molecular_function^alanine-tRNA ligase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,KEGG:xla:379958`KO:K07050,COG2872^synthetase,.,NA,NA,NA,NA,,
no,AD,DB,DN129028_c0_g1_i2,DN129028_c0_g1,RD21L_MOUSE,Double-strand-break repair protein rad21-like protein 1,.,NA,GO:0005694^cellular_component^chromosome,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:mmu:668929,ENOG410XRB4^Doublestrandbreak repair protein rad21,.,NA,NA,NA,NA,,
no,AD,DB,DN129028_c0_g1_i1,DN129028_c0_g1,RA21A_DANRE,Double-strand-break repair protein rad21 homolog A,RA21A_DANRE,Double-strand-break repair protein rad21 homolog A,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0016363^cellular_component^nuclear matrix,GO:0000922^cellular_component^spindle pole,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0030893^cellular_component^meiotic cohesin complex,GO:0016363^cellular_component^nuclear matrix,GO:0000922^cellular_component^spindle pole,KEGG:dre:322275`KO:K06670,ENOG410XRB4^Doublestrandbreak repair protein rad21,PF04825.13^Rad21_Rec8_N^N terminus of Rad21 / Rec8 like protein^6-105^E:2.9e-38,NA,NA,NA,NA,,
no,AD,DB,DN154239_c0_g1_i1,DN154239_c0_g1,DCAF6_HUMAN,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:55827`KO:K11795,ENOG410XQZP^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN111497_c0_g1_i1,DN111497_c0_g1,ZXDB_HUMAN,Zinc finger X-linked protein ZXDB,.,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:158586,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
no,AD,DB,DN172059_c0_g1_i1,DN172059_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,.,NA,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,.,NA,NA,NA,NA,KEGG:mmu:24131`KO:K19867,ENOG410XRD4^PDZ and LIM domain,.,NA,NA,NA,NA,,
no,AD,DB,DN192118_c0_g1_i1,DN192118_c0_g1,ARL8_DICDI,ADP-ribosylation factor-like protein 8,.,NA,GO:0005765^cellular_component^lysosomal membrane,GO:0005774^cellular_component^vacuolar membrane,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0283525`KO:K07955,ENOG410XNUK^ADP-ribosylation factor-like,.,NA,NA,NA,NA,,
no,AD,DB,DN111088_c0_g1_i1,DN111088_c0_g1,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:8816`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,.,NA,NA,NA,NA,,
no,AD,DB,DN108824_c0_g1_i7,DN108824_c0_g1,LDB3_HUMAN,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,.,PF00595.24^PDZ^PDZ domain^8-81^E:4.6e-16,NA,NA,NA,NA,,
no,AD,DB,DN108824_c0_g1_i20,DN108824_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,.,NA,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,.,NA,NA,NA,NA,KEGG:mmu:24131`KO:K19867,ENOG410XRD4^PDZ and LIM domain,.,NA,NA,NA,NA,,
no,AD,DB,DN108824_c0_g1_i6,DN108824_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,ENOG410XRD4^PDZ and LIM domain,PF00412.22^LIM^LIM domain^166-219^E:1.7e-10,PF00412.22^LIM^LIM domain^225-279^E:9e-15,PF00412.22^LIM^LIM domain^284-336^E:8.5e-13,NA,NA,,
no,AD,DB,DN108824_c0_g1_i14,DN108824_c0_g1,LDB3_HUMAN,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,.,PF00595.24^PDZ^PDZ domain^8-81^E:4.6e-16,NA,NA,NA,NA,,
no,AD,DB,DN108824_c0_g1_i2,DN108824_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,ENOG410XRD4^PDZ and LIM domain,PF15936.5^DUF4749^Domain of unknown function (DUF4749)^20-121^E:7.1e-27,PF00412.22^LIM^LIM domain^271-324^E:2.5e-10,PF00412.22^LIM^LIM domain^330-384^E:1.3e-14,PF00412.22^LIM^LIM domain^389-441^E:1.3e-12,NA,,
no,AD,DB,DN108824_c0_g1_i19,DN108824_c0_g1,LDB3_HUMAN,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,.,PF00595.24^PDZ^PDZ domain^8-81^E:8.6e-16,PF15936.5^DUF4749^Domain of unknown function (DUF4749)^206-309^E:2e-23,NA,NA,NA,,
no,AD,DB,DN108824_c0_g1_i18,DN108824_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,ENOG410XRD4^PDZ and LIM domain,PF15936.5^DUF4749^Domain of unknown function (DUF4749)^2-66^E:1.8e-11,PF00412.22^LIM^LIM domain^232-285^E:2.2e-10,PF00412.22^LIM^LIM domain^291-345^E:1.2e-14,PF00412.22^LIM^LIM domain^350-402^E:1.1e-12,NA,,
no,AD,DB,DN108824_c0_g1_i10,DN108824_c0_g1,LDB3_HUMAN,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,.,PF15936.5^DUF4749^Domain of unknown function (DUF4749)^2-66^E:2e-11,PF00412.22^LIM^LIM domain^289-342^E:2.4e-10,PF00412.22^LIM^LIM domain^348-402^E:1.3e-14,NA,NA,,
no,AD,DB,DN108824_c0_g1_i8,DN108824_c0_g1,LDB3_MOUSE,LIM domain-binding protein 3,LDB3_HUMAN,LIM domain-binding protein 3,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,KEGG:hsa:11155`KO:K19867,ENOG410XRD4^PDZ and LIM domain,PF00595.24^PDZ^PDZ domain^8-81^E:2.2e-15,PF15936.5^DUF4749^Domain of unknown function (DUF4749)^206-309^E:5.8e-23,PF00412.22^LIM^LIM domain^459-512^E:4e-10,PF00412.22^LIM^LIM domain^518-572^E:2.1e-14,PF00412.22^LIM^LIM domain^577-629^E:2e-12,,
no,AD,DB,DN108824_c0_g4_i1,DN108824_c0_g4,LDB3_HUMAN,LIM domain-binding protein 3,.,NA,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005856^cellular_component^cytoskeleton,GO:0031941^cellular_component^filamentous actin,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0031143^cellular_component^pseudopodium,.,NA,NA,NA,NA,KEGG:hsa:11155`KO:K19867,.,.,NA,NA,NA,NA,,
no,AD,DB,DN125827_c0_g1_i1,DN125827_c0_g1,LDB1_XENTR,LIM domain-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,.,NA,NA,NA,NA,KEGG:xtr:407886`KO:K15617,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN161618_c0_g1_i1,DN161618_c0_g1,ZN326_CHICK,DBIRD complex subunit ZNF326,.,NA,GO:0044609^cellular_component^DBIRD complex,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:gga:424512`KO:K13204,ENOG4111H5U^Zinc finger protein 326,.,NA,NA,NA,NA,,
no,AD,DB,DN190515_c0_g1_i1,DN190515_c0_g1,DCA13_CHICK,DDB1- and CUL4-associated factor 13,.,NA,GO:0030054^cellular_component^cell junction,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:gga:420263`KO:K11806,ENOG410XNX6^ddb1 and cul4 associated factor 13,.,NA,NA,NA,NA,,
no,AD,DB,DN122841_c0_g1_i1,DN122841_c0_g1,PCDBB_PANTR,Protocadherin beta-11,PCDBD_PANTR,Protocadherin beta-13,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF16492.5^Cadherin_C_2^Cadherin cytoplasmic C-terminal^81-157^E:8.8e-19,NA,NA,NA,NA,,
no,AD,DB,DN122841_c0_g1_i3,DN122841_c0_g1,PCDB1_PANTR,Protocadherin beta-1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:ptr:471658`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN122841_c0_g2_i1,DN122841_c0_g2,PCDB1_PANTR,Protocadherin beta-1,PCDB1_PANTR,Protocadherin beta-1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,KEGG:ptr:471658`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF08266.12^Cadherin_2^Cadherin-like^26-107^E:1.2e-29,NA,NA,NA,NA,,
no,AD,DB,DN100909_c0_g1_i3,DN100909_c0_g1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,.,NA,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,.,NA,NA,NA,NA,KEGG:xla:432147`KO:K11421,.,.,NA,NA,NA,NA,,
no,AD,DB,DN100909_c0_g1_i2,DN100909_c0_g1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,KEGG:xla:432147`KO:K11421,.,PF15140.6^DUF4573^Domain of unknown function (DUF4573)^9-148^E:9.8e-09,NA,NA,NA,NA,,
no,AD,DB,DN100909_c0_g1_i10,DN100909_c0_g1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,KEGG:xla:432147`KO:K11421,.,.,NA,NA,NA,NA,,
no,AD,DB,DN100909_c0_g1_i7,DN100909_c0_g1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,KEGG:xla:432147`KO:K11421,.,.,NA,NA,NA,NA,,
no,AD,DB,DN100909_c0_g1_i1,DN100909_c0_g1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,SETB1_XENLA,Histone-lysine N-methyltransferase SETDB1,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,GO:0005694^cellular_component^chromosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0018024^molecular_function^histone-lysine N-methyltransferase activity,GO:1990841^molecular_function^promoter-specific chromatin binding,KEGG:xla:432147`KO:K11421,.,.,NA,NA,NA,NA,,
no,AD,DB,DN123365_c0_g1_i4,DN123365_c0_g1,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:hsa:90379`KO:K11791,ENOG410ZN1V^DDB1 and CUL4 associated factor 15,.,NA,NA,NA,NA,,
no,AD,DB,DN123365_c0_g1_i2,DN123365_c0_g1,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:hsa:90379`KO:K11791,ENOG410ZN1V^DDB1 and CUL4 associated factor 15,.,NA,NA,NA,NA,,
no,AD,DB,DN123365_c0_g1_i5,DN123365_c0_g1,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,DCA15_HUMAN,DDB1- and CUL4-associated factor 15,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0032991^cellular_component^protein-containing complex,GO:0016567^biological_process^protein ubiquitination,NA,NA,KEGG:hsa:90379`KO:K11791,ENOG410ZN1V^DDB1 and CUL4 associated factor 15,.,NA,NA,NA,NA,,
no,AD,DB,DN101336_c0_g1_i1,DN101336_c0_g1,IFT46_DANRE,"Intraflagellar transport protein 46 homolog {ECO:0000250|UniProtKB:Q9DB07, ECO:0000312|ZFIN:ZDB-GENE-080102-3}",.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005737^cellular_component^cytoplasm,GO:0030992^cellular_component^intraciliary transport particle B,GO:0031514^cellular_component^motile cilium,.,NA,NA,NA,NA,.,ENOG410ZYJI^intraflagellar transport 46 homolog (Chlamydomonas),.,NA,NA,NA,NA,,
no,AD,DB,DN124813_c0_g1_i1,DN124813_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN101096_c0_g1_i1,DN101096_c0_g1,F83DB_XENLA,Protein FAM83D-B {ECO:0000305},F83DB_XENLA,Protein FAM83D-B {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,GO:0005737^cellular_component^cytoplasm,GO:0097431^cellular_component^mitotic spindle pole,GO:0051301^biological_process^cell division,GO:0008283^biological_process^cell population proliferation,GO:0051310^biological_process^metaphase plate congression,KEGG:xla:495259`KO:K16805,.,PF07894.12^FAM83^FAM83 A-H^22-127^E:3e-27,NA,NA,NA,NA,,
no,AD,DB,DN166851_c0_g1_i1,DN166851_c0_g1,LDB1_XENTR,LIM domain-binding protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0030274^molecular_function^LIM domain binding,GO:0042803^molecular_function^protein homodimerization activity,GO:0001102^molecular_function^RNA polymerase II activating transcription factor binding,.,NA,NA,NA,NA,KEGG:xtr:407886`KO:K15617,ENOG410YZVH^Lim domain binding,.,NA,NA,NA,NA,,
no,AD,DB,DN143036_c1_g1_i1,DN143036_c1_g1,PCDBE_MOUSE,Protocadherin beta-14,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:mmu:93885`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN102079_c0_g1_i2,DN102079_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN101575_c0_g1_i1,DN101575_c0_g1,FCL_DICDI,GDP-L-fucose synthase,.,NA,GO:0050662^molecular_function^coenzyme binding,GO:0050577^molecular_function^GDP-L-fucose synthase activity,GO:0016853^molecular_function^isomerase activity,GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0270184`KO:K02377,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DB,DN142391_c0_g1_i1,DN142391_c0_g1,DCA12_MACFA,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:mcf:101925316`KO:K11803,.,.,NA,NA,NA,NA,,
no,AD,DB,DN109692_c0_g1_i2,DN109692_c0_g1,DCAF5_HUMAN,DDB1- and CUL4-associated factor 5,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:8816`KO:K11800,ENOG410ZPFW^ddb1 and cul4 associated factor 5,.,NA,NA,NA,NA,,
no,AD,DB,DN192372_c0_g1_i1,DN192372_c0_g1,PCDB1_HUMAN,Protocadherin beta-1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,NA,NA,NA,NA,KEGG:hsa:29930`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN137015_c0_g1_i1,DN137015_c0_g1,DCAF6_PONAB,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172900`KO:K11795,.,.,NA,NA,NA,NA,,
no,AD,DB,DN174252_c0_g1_i1,DN174252_c0_g1,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,BTBDB_HUMAN,Ankyrin repeat and BTB/POZ domain-containing protein BTBD11,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0046982^molecular_function^protein heterodimerization activity,GO:0060395^biological_process^SMAD protein signal transduction,NA,NA,KEGG:hsa:121551`KO:K10483,ENOG410XRDX^BTB (POZ) domain containing,.,NA,NA,NA,NA,,
no,AD,DB,DN162928_c0_g1_i1,DN162928_c0_g1,MCF2L_RAT,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0019898^cellular_component^extrinsic component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008289^molecular_function^lipid binding,GO:0005089^molecular_function^Rho guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,.,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN262919_c0_g1_i1,DN262919_c0_g1,ELP3_DICDI,Elongator complex protein 3 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0033588^cellular_component^Elongator holoenzyme complex,GO:0005634^cellular_component^nucleus,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0051536^molecular_function^iron-sulfur cluster binding,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0290103`KO:K07739,COG1243^Histone acetyltransferase,.,NA,NA,NA,NA,,
no,AD,DB,DN237086_c0_g1_i1,DN237086_c0_g1,DDB1_XENLA,DNA damage-binding protein 1,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0031464^cellular_component^Cul4A-RING E3 ubiquitin ligase complex,GO:0031465^cellular_component^Cul4B-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:xla:399026`KO:K10610,.,.,NA,NA,NA,NA,,
no,AD,DB,DN279651_c0_g1_i1,DN279651_c0_g1,CLCA_DICDI,Chloride channel protein A,CLCA_DICDI,Chloride channel protein A,GO:0034707^cellular_component^chloride channel complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015108^molecular_function^chloride transmembrane transporter activity,GO:0022857^molecular_function^transmembrane transporter activity,GO:0005247^molecular_function^voltage-gated chloride channel activity,GO:0034707^cellular_component^chloride channel complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015108^molecular_function^chloride transmembrane transporter activity,GO:0022857^molecular_function^transmembrane transporter activity,GO:0005247^molecular_function^voltage-gated chloride channel activity,KEGG:ddi:DDB_G0294096`KO:K05016,COG0038^chloride channel,.,NA,NA,NA,NA,,
no,AD,DB,DN263699_c0_g1_i1,DN263699_c0_g1,PCDB1_PANTR,Protocadherin beta-1,PCDBF_PANTR,Protocadherin beta-15,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0032391^cellular_component^photoreceptor connecting cilium,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,KEGG:ptr:462137`KO:K16494,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^19-111^E:8.3e-14,NA,NA,NA,NA,,
no,AD,DB,DN227861_c0_g1_i1,DN227861_c0_g1,DCAF1_HUMAN,DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911},.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:9730`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN209354_c0_g1_i1,DN209354_c0_g1,VATA_DICDI,V-type proton ATPase catalytic subunit A,.,NA,GO:0000331^cellular_component^contractile vacuole,GO:0030139^cellular_component^endocytic vesicle,GO:0045335^cellular_component^phagocytic vesicle,GO:0005886^cellular_component^plasma membrane,"GO:0033180^cellular_component^proton-transporting V-type ATPase, V1 domain",.,NA,NA,NA,NA,KEGG:ddi:DDB_G0287127`KO:K02145,COG1155^Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity),.,NA,NA,NA,NA,,
no,AD,DB,DN219612_c0_g1_i2,DN219612_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN219612_c0_g1_i1,DN219612_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN219612_c0_g1_i3,DN219612_c0_g1,DCA12_CHICK,DDB1- and CUL4-associated factor 12,.,NA,GO:0005813^cellular_component^centrosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:gga:427396`KO:K11803,ENOG410XTH6^ddb1 and cul4 associated factor,.,NA,NA,NA,NA,,
no,AD,DB,DN208424_c0_g1_i1,DN208424_c0_g1,MYBV_DICDI,Myb-like protein V,.,NA,GO:0003677^molecular_function^DNA binding,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279281,.,.,NA,NA,NA,NA,,
no,AD,DB,DN208424_c0_g1_i4,DN208424_c0_g1,MYBV_DICDI,Myb-like protein V,.,NA,GO:0003677^molecular_function^DNA binding,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279281,.,.,NA,NA,NA,NA,,
no,AD,DB,DN208424_c0_g1_i3,DN208424_c0_g1,MYBV_DICDI,Myb-like protein V,.,NA,GO:0003677^molecular_function^DNA binding,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0279281,.,.,NA,NA,NA,NA,,
no,AD,DB,DN262016_c0_g1_i1,DN262016_c0_g1,DBNL_HUMAN,Drebrin-like protein,.,NA,GO:0005938^cellular_component^cell cortex,GO:0030054^cellular_component^cell junction,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,.,NA,NA,NA,NA,KEGG:hsa:28988`KO:K20520,ENOG410XRVX^Drebrin-like,.,NA,NA,NA,NA,,
no,AD,DB,DN290372_c0_g1_i1,DN290372_c0_g1,DCAF6_PONAB,DDB1- and CUL4-associated factor 6,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005634^cellular_component^nucleus,GO:0016567^biological_process^protein ubiquitination,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172900`KO:K11795,.,.,NA,NA,NA,NA,,
no,AD,DB,DN214126_c0_g1_i1,DN214126_c0_g1,SAE2_DICDI,SUMO-activating enzyme subunit 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0031510^cellular_component^SUMO activating enzyme complex,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0019948^molecular_function^SUMO activating enzyme activity,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0286919`KO:K10685,COG0476^small protein activating enzyme activity,.,NA,NA,NA,NA,,
no,AD,DB,DN334179_c0_g1_i1,DN334179_c0_g1,DCAF1_MOUSE,DDB1- and CUL4-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4B6},.,NA,GO:0008180^cellular_component^COP9 signalosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:321006`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN368180_c0_g1_i1,DN368180_c0_g1,DCA10_HUMAN,DDB1- and CUL4-associated factor 10,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005654^cellular_component^nucleoplasm,GO:0043687^biological_process^post-translational protein modification,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:hsa:79269`KO:K11802,ENOG410ZF1A^DDB1 and CUL4 associated factor 10,.,NA,NA,NA,NA,,
no,AD,DB,DN396566_c0_g1_i1,DN396566_c0_g1,CLCA_DICDI,Chloride channel protein A,CLCA_DICDI,Chloride channel protein A,GO:0034707^cellular_component^chloride channel complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015108^molecular_function^chloride transmembrane transporter activity,GO:0022857^molecular_function^transmembrane transporter activity,GO:0005247^molecular_function^voltage-gated chloride channel activity,GO:0034707^cellular_component^chloride channel complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0015108^molecular_function^chloride transmembrane transporter activity,GO:0022857^molecular_function^transmembrane transporter activity,GO:0005247^molecular_function^voltage-gated chloride channel activity,KEGG:ddi:DDB_G0294096`KO:K05016,COG0038^chloride channel,PF00571.28^CBS^CBS domain^79-120^E:0.0012,NA,NA,NA,NA,,
no,AD,DB,DN320106_c0_g1_i1,DN320106_c0_g1,MCCB_DICDI,"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial",.,NA,GO:1905202^cellular_component^methylcrotonoyl-CoA carboxylase complex,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004485^molecular_function^methylcrotonoyl-CoA carboxylase activity,.,NA,NA,NA,NA,KEGG:ddi:DDB_G0271960`KO:K01969,COG4799^carboxylase,.,NA,NA,NA,NA,,
no,AD,DB,DN357259_c0_g1_i1,DN357259_c0_g1,SSBP4_HUMAN,Single-stranded DNA-binding protein 4,.,NA,GO:0005634^cellular_component^nucleus,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0003697^molecular_function^single-stranded DNA binding,GO:0045944^biological_process^positive regulation of transcription by RNA polymerase II,NA,.,NA,NA,NA,NA,KEGG:hsa:170463,ENOG410XPQX^midbrain-hindbrain boundary initiation,.,NA,NA,NA,NA,,
no,AD,DB,DN393295_c0_g1_i1,DN393295_c0_g1,DC12A_XENLA,DDB1- and CUL4-associated factor 12-A,.,NA,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005815^cellular_component^microtubule organizing center,GO:0016567^biological_process^protein ubiquitination,NA,.,NA,NA,NA,NA,KEGG:xla:494761`KO:K11803,.,.,NA,NA,NA,NA,,
no,AD,DB,DN375247_c0_g1_i1,DN375247_c0_g1,DCAF1_MOUSE,DDB1- and CUL4-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4B6},.,NA,GO:0008180^cellular_component^COP9 signalosome,GO:0080008^cellular_component^Cul4-RING E3 ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:321006`KO:K11789,ENOG410XR8C^Vpr (HIV-1) binding protein,.,NA,NA,NA,NA,,
no,AD,DB,DN422323_c0_g1_i1,DN422323_c0_g1,ODBB_RAT,"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial",.,NA,GO:0005947^cellular_component^mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0005739^cellular_component^mitochondrion,GO:0003863^molecular_function^3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity,GO:0003826^molecular_function^alpha-ketoacid dehydrogenase activity,GO:0044877^molecular_function^protein-containing complex binding,.,NA,NA,NA,NA,KEGG:rno:29711`KO:K00167,"COG0022^Dehydrogenase, E1 component",.,NA,NA,NA,NA,,
no,AD,DB,DN446873_c0_g1_i1,DN446873_c0_g1,MCF2L_HUMAN,Guanine nucleotide exchange factor DBS,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0012505^cellular_component^endomembrane system,GO:0005615^cellular_component^extracellular space,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:23263`KO:K20685,ENOG410XNYV^mcf.2 cell line derived transforming sequence-like,.,NA,NA,NA,NA,,
no,AD,DB,DN428551_c0_g1_i1,DN428551_c0_g1,PCDB5_PANTR,Protocadherin beta-5,PCDB5_PANTR,Protocadherin beta-5,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0007155^biological_process^cell adhesion,GO:0007156^biological_process^homophilic cell adhesion via plasma membrane adhesion molecules,NA,.,ENOG410XQHI^Cadherins are calcium dependent cell adhesion proteins (By similarity),PF00028.17^Cadherin^Cadherin domain^36-128^E:3.6e-13,NA,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i20,DN1500_c0_g1,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:mmu:230073`KO:K12646,COG1111^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^77-137^E:1.4e-12,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^212-329^E:1.3e-36,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i27,DN1500_c0_g1,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:mmu:230073`KO:K12646,COG1111^helicase,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^49-166^E:2.5e-37,NA,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i34,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:hsa:23586`KO:K12646,COG1111^helicase,PF18119.1^RIG-I_C^RIG-I receptor C-terminal domain^8-116^E:3e-29,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^126-248^E:2.5e-14,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^323-440^E:2.4e-36,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i13,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,.,NA,NA,NA,NA,KEGG:hsa:23586`KO:K12646,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i15,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,.,NA,NA,NA,NA,KEGG:hsa:23586`KO:K12646,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i33,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:hsa:23586`KO:K12646,COG1111^helicase,PF18119.1^RIG-I_C^RIG-I receptor C-terminal domain^8-116^E:3e-29,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^126-248^E:2.5e-14,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^323-440^E:2.4e-36,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i1,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:hsa:23586`KO:K12646,COG1111^helicase,PF18119.1^RIG-I_C^RIG-I receptor C-terminal domain^57-197^E:2.6e-38,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^207-329^E:3.3e-14,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^404-521^E:3.2e-36,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i9,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,.,NA,NA,NA,NA,KEGG:hsa:23586`KO:K12646,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i23,DN1500_c0_g1,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:mmu:230073`KO:K12646,COG1111^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^77-137^E:1.4e-12,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^212-329^E:1.3e-36,NA,NA,NA,,
yes,AD,DDX58,DN1500_c0_g1_i12,DN1500_c0_g1,DDX58_HUMAN,Probable ATP-dependent RNA helicase DDX58,DDX58_MOUSE,Probable ATP-dependent RNA helicase DDX58,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0005923^cellular_component^bicellular tight junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0032587^cellular_component^ruffle membrane,KEGG:mmu:230073`KO:K12646,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^22-113^E:3.4e-20,NA,NA,NA,NA,,
yes,AD,DHX,DN5618_c0_g1_i3,DN5618_c0_g1,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,KEGG:hsa:90957`KO:K13026,COG1643^helicase,PF05773.22^RWD^RWD domain^235-408^E:1.7e-14,PF00642.24^zf-CCCH^Zinc finger C-x8-C-x5-C-x3-H type (and similar)^293-314^E:0.0002,PF18044.1^zf-CCCH_4^CCCH-type zinc finger^295-315^E:2.6e-07,"PF14608.6^zf-CCCH_2^RNA-binding, Nab2-type zinc finger^295-314^E:0.044",PF00270.29^DEAD^DEAD/DEAH box helicase^537-691^E:2.2e-10,,
yes,AD,DHX,DN37870_c0_g1_i1,DN37870_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN37870_c0_g1_i6,DN37870_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN37870_c0_g1_i10,DN37870_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN37870_c0_g1_i11,DN37870_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN37860_c0_g1_i1,DN37860_c0_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN3822_c1_g1_i5,DN3822_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN3822_c1_g1_i2,DN3822_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:gga:420376`KO:K13185,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^17-103^E:7.1e-09,NA,NA,NA,NA,,
yes,AD,DHX,DN3822_c1_g1_i8,DN3822_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:gga:420376`KO:K13185,COG1643^helicase,PF00035.26^dsrm^Double-stranded RNA binding motif^261-328^E:8.3e-06,PF00270.29^DEAD^DEAD/DEAH box helicase^456-607^E:5.4e-07,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^675-798^E:5.2e-13,PF04408.23^HA2^Helicase associated domain (HA2)^863-946^E:9.2e-14,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^1028-1114^E:1.6e-07,,
yes,AD,DHX,DN3822_c1_g1_i4,DN3822_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:gga:420376`KO:K13185,COG1643^helicase,PF00035.26^dsrm^Double-stranded RNA binding motif^261-328^E:8.3e-06,PF00270.29^DEAD^DEAD/DEAH box helicase^456-607^E:5.4e-07,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^675-798^E:5.2e-13,PF04408.23^HA2^Helicase associated domain (HA2)^863-946^E:9.2e-14,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^1028-1114^E:1.6e-07,,
yes,AD,DHX,DN3822_c1_g1_i3,DN3822_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:gga:420376`KO:K13185,COG1643^helicase,PF00035.26^dsrm^Double-stranded RNA binding motif^261-328^E:5.7e-06,PF00270.29^DEAD^DEAD/DEAH box helicase^456-607^E:3.5e-07,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^675-798^E:3.4e-13,NA,NA,,
yes,AD,DHX,DN28000_c1_g1_i1,DN28000_c1_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN28000_c1_g2_i4,DN28000_c1_g2,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN28000_c1_g2_i3,DN28000_c1_g2,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN28000_c1_g2_i1,DN28000_c1_g2,DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:rno:310461`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN28000_c1_g2_i2,DN28000_c1_g2,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DHX,DN69585_c0_g1_i1,DN69585_c0_g1,ADHX_BOVIN,Alcohol dehydrogenase class-3 {ECO:0000250|UniProtKB:P11766},.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0005504^molecular_function^fatty acid binding,GO:0018467^molecular_function^formaldehyde dehydrogenase activity,.,NA,NA,NA,NA,KEGG:bta:505515`KO:K00121,COG1062^alcohol dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DHX,DN9688_c0_g1_i1,DN9688_c0_g1,EDC3_CHICK,Enhancer of mRNA-decapping protein 3,EDC3_CHICK,Enhancer of mRNA-decapping protein 3,GO:0000932^cellular_component^P-body,GO:0003729^molecular_function^mRNA binding,GO:1990174^molecular_function^phosphodiesterase decapping endonuclease activity,GO:0033962^biological_process^cytoplasmic mRNA processing body assembly,GO:0031087^biological_process^deadenylation-independent decapping of nuclear-transcribed mRNA,GO:0000932^cellular_component^P-body,GO:0003729^molecular_function^mRNA binding,GO:1990174^molecular_function^phosphodiesterase decapping endonuclease activity,GO:0033962^biological_process^cytoplasmic mRNA processing body assembly,GO:0031087^biological_process^deadenylation-independent decapping of nuclear-transcribed mRNA,KEGG:gga:415294`KO:K12615,COG0062^NADHX epimerase activity,PF12701.7^LSM14^Scd6-like Sm domain^4-66^E:1.6e-09,PF16598.5^Edc3_linker^Linker region of enhancer of mRNA-decapping protein 3^103-195^E:5.5e-44,PF09532.10^FDF^FDF domain^198-298^E:7.8e-15,PF03853.15^YjeF_N^YjeF-related protein N-terminus^303-444^E:1.2e-19,NA,,
no,AD,DHX,DN9688_c0_g1_i3,DN9688_c0_g1,EDC3_CHICK,Enhancer of mRNA-decapping protein 3,EDC3_CHICK,Enhancer of mRNA-decapping protein 3,GO:0000932^cellular_component^P-body,GO:0003729^molecular_function^mRNA binding,GO:1990174^molecular_function^phosphodiesterase decapping endonuclease activity,GO:0033962^biological_process^cytoplasmic mRNA processing body assembly,GO:0031087^biological_process^deadenylation-independent decapping of nuclear-transcribed mRNA,GO:0000932^cellular_component^P-body,GO:0003729^molecular_function^mRNA binding,GO:1990174^molecular_function^phosphodiesterase decapping endonuclease activity,GO:0033962^biological_process^cytoplasmic mRNA processing body assembly,GO:0031087^biological_process^deadenylation-independent decapping of nuclear-transcribed mRNA,KEGG:gga:415294`KO:K12615,COG0062^NADHX epimerase activity,PF12701.7^LSM14^Scd6-like Sm domain^4-66^E:1.6e-09,PF16598.5^Edc3_linker^Linker region of enhancer of mRNA-decapping protein 3^103-195^E:5.5e-44,PF09532.10^FDF^FDF domain^198-298^E:7.8e-15,PF03853.15^YjeF_N^YjeF-related protein N-terminus^303-444^E:1.2e-19,NA,,
no,AD,DHX,DN9688_c0_g1_i2,DN9688_c0_g1,EDC3_CHICK,Enhancer of mRNA-decapping protein 3,.,NA,GO:0000932^cellular_component^P-body,GO:0003729^molecular_function^mRNA binding,GO:1990174^molecular_function^phosphodiesterase decapping endonuclease activity,GO:0033962^biological_process^cytoplasmic mRNA processing body assembly,GO:0031087^biological_process^deadenylation-independent decapping of nuclear-transcribed mRNA,.,NA,NA,NA,NA,KEGG:gga:415294`KO:K12615,COG0062^NADHX epimerase activity,.,NA,NA,NA,NA,,
yes,AD,DHX,DN9638_c0_g1_i2,DN9638_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN9638_c0_g2_i1,DN9638_c0_g2,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN9638_c0_g3_i1,DN9638_c0_g3,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN9603_c0_g1_i1,DN9603_c0_g1,DHX8_MOUSE,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,PF00575.23^S1^S1 RNA binding domain^157-227^E:6.6e-15,NA,NA,NA,NA,,
yes,AD,DHX,DN9603_c0_g1_i2,DN9603_c0_g1,DHX8_MOUSE,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,PF00575.23^S1^S1 RNA binding domain^161-231^E:6.7e-15,NA,NA,NA,NA,,
yes,AD,DHX,DN17021_c0_g1_i7,DN17021_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN17021_c0_g1_i8,DN17021_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN24587_c1_g1_i1,DN24587_c1_g1,DHX8_MOUSE,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,.,NA,NA,NA,NA,KEGG:mmu:217207`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN15440_c0_g2_i1,DN15440_c0_g2,DHX16_HUMAN,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:hsa:8449`KO:K12813,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN38127_c0_g1_i2,DN38127_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN38127_c0_g1_i1,DN38127_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN13860_c0_g1_i11,DN13860_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN13860_c0_g3_i1,DN13860_c0_g3,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN97046_c0_g1_i1,DN97046_c0_g1,DHX36_BOVIN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:bta:509583`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12018_c0_g1_i2,DN12018_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12018_c0_g1_i1,DN12018_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,.,NA,NA,NA,NA,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12002_c0_g1_i1,DN12002_c0_g1,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},.,NA,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,.,NA,NA,NA,NA,KEGG:hsa:54505`KO:K18995,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12002_c0_g2_i2,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^558-714^E:1.5e-10,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^828-962^E:1.5e-12,PF04408.23^HA2^Helicase associated domain (HA2)^1026-1101^E:5.8e-16,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^1193-1279^E:2.9e-13,NA,,
yes,AD,DHX,DN12002_c0_g2_i7,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},.,NA,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,.,NA,NA,NA,NA,KEGG:hsa:54505`KO:K18995,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12002_c0_g2_i5,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12002_c0_g2_i4,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^558-714^E:1.4e-10,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^828-962^E:1.4e-12,PF04408.23^HA2^Helicase associated domain (HA2)^1026-1101^E:5.4e-16,NA,NA,,
yes,AD,DHX,DN12002_c0_g2_i1,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^420-576^E:1.3e-10,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^690-824^E:1.3e-12,PF04408.23^HA2^Helicase associated domain (HA2)^888-963^E:5.1e-16,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^1055-1141^E:2.5e-13,NA,,
yes,AD,DHX,DN12002_c0_g2_i8,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^353-509^E:1.2e-10,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^623-757^E:1.2e-12,PF04408.23^HA2^Helicase associated domain (HA2)^821-896^E:4.7e-16,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^988-1074^E:2.3e-13,NA,,
yes,AD,DHX,DN12002_c0_g2_i6,DN12002_c0_g2,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,KEGG:hsa:54505`KO:K18995,COG1643^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^120-254^E:5e-13,PF04408.23^HA2^Helicase associated domain (HA2)^318-393^E:2.1e-16,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^485-571^E:1.1e-13,NA,NA,,
yes,AD,DHX,DN12002_c0_g3_i1,DN12002_c0_g3,DHX29_MOUSE,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},.,NA,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0005739^cellular_component^mitochondrion,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0043024^molecular_function^ribosomal small subunit binding,.,NA,NA,NA,NA,KEGG:mmu:218629`KO:K18995,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN53940_c0_g1_i1,DN53940_c0_g1,DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:rno:310461`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DHX,DN85622_c0_g1_i1,DN85622_c0_g1,ADHX_HORSE,Alcohol dehydrogenase class-3 {ECO:0000250|UniProtKB:P11766},.,NA,GO:0005829^cellular_component^cytosol,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i8,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,KEGG:mmu:71723`KO:K20101,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^23-120^E:7.5e-17,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^263-368^E:1.9e-13,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i15,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,KEGG:mmu:71723`KO:K20101,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^94-191^E:9.1e-17,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^334-439^E:2.3e-13,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i5,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i7,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i10,DN2716_c0_g1,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",KEGG:hsa:9704`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i9,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i3,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i12,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2716_c0_g1_i14,DN2716_c0_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",KEGG:hsa:9704`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN2752_c0_g1_i1,DN2752_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN15121_c0_g1_i1,DN15121_c0_g1,DHX58_MOUSE,Probable ATP-dependent RNA helicase DHX58,DHX58_MOUSE,Probable ATP-dependent RNA helicase DHX58,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,KEGG:mmu:80861`KO:K12649,COG1111^helicase,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^2-31^E:6.6e-08,NA,NA,NA,NA,,
yes,AD,DHX,DN15121_c0_g1_i3,DN15121_c0_g1,DHX58_MOUSE,Probable ATP-dependent RNA helicase DHX58,DHX58_MOUSE,Probable ATP-dependent RNA helicase DHX58,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,KEGG:mmu:80861`KO:K12649,COG1111^helicase,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^2-32^E:1.4e-07,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i9,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:mmu:13204`KO:K12820,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^112-180^E:5.9e-20,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i17,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,KEGG:pon:100174435`KO:K12820,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^163-311^E:1.4e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^353-491^E:2.7e-12,PF04408.23^HA2^Helicase associated domain (HA2)^554-611^E:1.8e-18,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i8,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i6,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i3,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,KEGG:pon:100174435`KO:K12820,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^163-311^E:1.4e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^353-491^E:2.7e-12,PF04408.23^HA2^Helicase associated domain (HA2)^554-611^E:1.8e-18,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i11,DN12747_c0_g1,DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:mmu:13204`KO:K12820,COG1643^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^1-60^E:2.5e-05,PF04408.23^HA2^Helicase associated domain (HA2)^123-211^E:7.1e-24,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^273-349^E:9.1e-23,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i5,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:mmu:13204`KO:K12820,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^112-180^E:5.9e-20,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i16,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g1_i14,DN12747_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:mmu:13204`KO:K12820,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^112-180^E:5.9e-20,NA,NA,NA,NA,,
yes,AD,DHX,DN12747_c0_g2_i1,DN12747_c0_g2,DHX15_MOUSE,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005689^cellular_component^U12-type spliceosomal complex,GO:0071008^cellular_component^U2-type post-mRNA release spliceosomal complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:mmu:13204`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN681_c1_g1_i7,DN681_c1_g1,DHX16_PIG,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,DHX16_PIG,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:ssc:100144456`KO:K12813,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN681_c1_g1_i2,DN681_c1_g1,DHX16_PIG,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:ssc:100144456`KO:K12813,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN681_c1_g1_i3,DN681_c1_g1,DHX16_PANTR,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:ptr:462546`KO:K12813,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN681_c1_g1_i4,DN681_c1_g1,DHX16_HUMAN,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,DHX16_HUMAN,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,KEGG:hsa:8449`KO:K12813,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^1-80^E:5.4e-12,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^125-201^E:5.6e-21,NA,NA,NA,,
yes,AD,DHX,DN3163_c0_g1_i1,DN3163_c0_g1,DHX8_MOUSE,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^117-245^E:1.3e-13,PF04408.23^HA2^Helicase associated domain (HA2)^307-395^E:4.3e-25,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^453-529^E:6.4e-26,NA,NA,,
yes,AD,DHX,DN11835_c1_g1_i5,DN11835_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i4,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^106-244^E:2.5e-32,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i2,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,NA,NA,NA,NA,.,COG0062^NADHX epimerase activity,.,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i7,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^111-249^E:2.6e-32,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i3,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,NA,NA,NA,NA,.,COG0062^NADHX epimerase activity,.,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i10,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_MONDO,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0044297^cellular_component^cell body,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0005739^cellular_component^mitochondrion,KEGG:mdo:100018290`KO:K17759,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^59-150^E:2.7e-14,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i8,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_MONDO,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0044297^cellular_component^cell body,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0005739^cellular_component^mitochondrion,KEGG:mdo:100018290`KO:K17759,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^59-224^E:3.1e-36,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i12,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_HUMAN,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0044297^cellular_component^cell body,GO:0005929^cellular_component^cilium,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:128240`KO:K17759,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^115-179^E:1.6e-10,NA,NA,NA,NA,,
no,AD,DHX,DN7981_c0_g1_i9,DN7981_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,COG0062^NADHX epimerase activity,PF03853.15^YjeF_N^YjeF-related protein N-terminus^115-253^E:2.7e-32,NA,NA,NA,NA,,
yes,AD,DHX,DN61781_c0_g1_i2,DN61781_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN98173_c0_g1_i1,DN98173_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,.,NA,NA,NA,NA,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN21361_c0_g1_i1,DN21361_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN10756_c0_g1_i2,DN10756_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,.,NA,NA,NA,NA,KEGG:pon:100172442`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN10756_c0_g1_i6,DN10756_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,KEGG:pon:100172442`KO:K13117,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^1-55^E:2.5e-08,NA,NA,NA,NA,,
yes,AD,DHX,DN43291_c0_g1_i1,DN43291_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN43291_c1_g1_i1,DN43291_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN43291_c3_g1_i1,DN43291_c3_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7797_c0_g1_i3,DN7797_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,.,NA,NA,NA,NA,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7797_c0_g1_i1,DN7797_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,.,NA,NA,NA,NA,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7797_c0_g1_i2,DN7797_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN33404_c1_g1_i1,DN33404_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN50693_c0_g1_i1,DN50693_c0_g1,DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:rno:310461`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN50693_c2_g1_i1,DN50693_c2_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i3,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^41-125^E:9.5e-25,NA,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i7,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^267-420^E:3.4e-10,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^590-675^E:2.1e-08,PF04408.23^HA2^Helicase associated domain (HA2)^737-858^E:3.3e-23,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^925-1009^E:9e-24,NA,,
yes,AD,DHX,DN6819_c0_g2_i10,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^41-125^E:9.5e-25,NA,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i5,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^267-420^E:2.8e-10,PF13401.6^AAA_22^AAA domain^274-413^E:4.2e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^590-675^E:1.7e-08,PF04408.23^HA2^Helicase associated domain (HA2)^737-858^E:2.7e-23,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^925-995^E:1.2e-18,,
yes,AD,DHX,DN6819_c0_g2_i2,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^267-420^E:3e-10,PF13401.6^AAA_22^AAA domain^274-413^E:4.5e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^590-675^E:1.8e-08,PF04408.23^HA2^Helicase associated domain (HA2)^737-858^E:2.9e-23,NA,,
yes,AD,DHX,DN6819_c0_g2_i9,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^267-420^E:9.5e-11,PF13401.6^AAA_22^AAA domain^274-413^E:1.5e-06,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i8,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:57647`KO:K14780,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i1,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^58-143^E:7.7e-09,PF04408.23^HA2^Helicase associated domain (HA2)^205-326^E:1.1e-23,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^393-477^E:3.3e-24,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i6,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,KEGG:hsa:57647`KO:K14780,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^41-125^E:9.5e-25,NA,NA,NA,NA,,
yes,AD,DHX,DN6819_c0_g2_i4,DN6819_c0_g2,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:57647`KO:K14780,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7276_c0_g1_i16,DN7276_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,KEGG:hsa:60625`KO:K13117,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^48-123^E:1.1e-20,NA,NA,NA,NA,,
yes,AD,DHX,DN7276_c0_g1_i13,DN7276_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7276_c0_g1_i23,DN7276_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN7276_c0_g1_i12,DN7276_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN44731_c0_g1_i1,DN44731_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN44731_c0_g1_i2,DN44731_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN164_c3_g1_i2,DN164_c3_g1,DHX58_HUMAN,Probable ATP-dependent RNA helicase DHX58,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,.,NA,NA,NA,NA,KEGG:hsa:79132`KO:K12649,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN164_c3_g1_i7,DN164_c3_g1,DHX58_HUMAN,Probable ATP-dependent RNA helicase DHX58,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,.,NA,NA,NA,NA,KEGG:hsa:79132`KO:K12649,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12534_c0_g1_i3,DN12534_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,KEGG:hsa:60625`KO:K13117,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^67-108^E:9.1e-10,NA,NA,NA,NA,,
yes,AD,DHX,DN12534_c0_g1_i4,DN12534_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:60625`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN12534_c0_g1_i5,DN12534_c0_g1,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,DHX35_HUMAN,Probable ATP-dependent RNA helicase DHX35,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0001701^biological_process^in utero embryonic development,KEGG:hsa:60625`KO:K13117,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^84-125^E:1.2e-09,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i9,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i4,DN19984_c0_g2,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i1,DN19984_c0_g2,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i11,DN19984_c0_g2,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i17,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i18,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i24,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i22,DN19984_c0_g2,DHX9_XENLA,ATP-dependent RNA helicase A protein {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0005815^cellular_component^microtubule organizing center,.,NA,NA,NA,NA,KEGG:xla:447207`KO:K13184,.,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i21,DN19984_c0_g2,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i10,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i15,DN19984_c0_g2,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19984_c0_g2_i5,DN19984_c0_g2,DHX9_MOUSE,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:mmu:13211`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN19915_c0_g1_i2,DN19915_c0_g1,DHX33_MOUSE,ATP-dependent RNA helicase DHX33 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:216877`KO:K17820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN3063_c0_g1_i6,DN3063_c0_g1,DHX33_HUMAN,ATP-dependent RNA helicase DHX33 {ECO:0000305},DHX33_HUMAN,ATP-dependent RNA helicase DHX33 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:56919`KO:K17820,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^37-185^E:4.9e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^232-356^E:8.1e-14,PF04408.23^HA2^Helicase associated domain (HA2)^419-510^E:4.3e-18,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^568-643^E:4e-16,NA,,
yes,AD,DHX,DN3063_c0_g1_i2,DN3063_c0_g1,DHX33_HUMAN,ATP-dependent RNA helicase DHX33 {ECO:0000305},DHX33_HUMAN,ATP-dependent RNA helicase DHX33 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:56919`KO:K17820,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^32-107^E:1.4e-17,NA,NA,NA,NA,,
yes,AD,DHX,DN57147_c0_g1_i1,DN57147_c0_g1,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,.,NA,NA,NA,NA,KEGG:hsa:90957`KO:K13026,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN73758_c0_g1_i1,DN73758_c0_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5502_c1_g1_i1,DN5502_c1_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",KEGG:hsa:9704`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5502_c1_g1_i5,DN5502_c1_g1,DHX34_MOUSE,Probable ATP-dependent RNA helicase DHX34,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0000956^biological_process^nuclear-transcribed mRNA catabolic process,.,NA,NA,NA,NA,KEGG:mmu:71723`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5502_c1_g2_i1,DN5502_c1_g2,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,DHX34_HUMAN,Probable ATP-dependent RNA helicase DHX34,GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0016020^cellular_component^membrane,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:2000623^biological_process^negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",KEGG:hsa:9704`KO:K20101,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5584_c1_g1_i9,DN5584_c1_g1,DQX1_BOVIN,ATP-dependent RNA helicase DQX1,DHX32_MOUSE,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003678^molecular_function^DNA helicase activity,GO:0003723^molecular_function^RNA binding,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,KEGG:mmu:101437`KO:K18994,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^9-98^E:1.6e-22,NA,NA,NA,NA,,
yes,AD,DHX,DN5584_c1_g1_i12,DN5584_c1_g1,DHX32_MOUSE,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,DHX32_MOUSE,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,KEGG:mmu:101437`KO:K18994,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN83126_c0_g1_i2,DN83126_c0_g1,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,.,NA,NA,NA,NA,KEGG:hsa:90957`KO:K13026,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN83126_c0_g1_i1,DN83126_c0_g1,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,.,NA,NA,NA,NA,KEGG:hsa:90957`KO:K13026,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5073_c0_g1_i10,DN5073_c0_g1,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,KEGG:hsa:79665`KO:K18711,COG1643^helicase,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^8-142^E:2.6e-14,PF04408.23^HA2^Helicase associated domain (HA2)^205-273^E:9.8e-14,NA,NA,NA,,
yes,AD,DHX,DN5073_c0_g1_i5,DN5073_c0_g1,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,.,NA,NA,NA,NA,KEGG:hsa:79665`KO:K18711,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN5073_c0_g1_i8,DN5073_c0_g1,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,KEGG:hsa:79665`KO:K18711,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^92-169^E:1.8e-14,NA,NA,NA,NA,,
yes,AD,DHX,DN5073_c0_g1_i1,DN5073_c0_g1,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,DHX40_MOUSE,Probable ATP-dependent RNA helicase DHX40,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,KEGG:mmu:67487`KO:K18711,COG1643^helicase,PF13401.6^AAA_22^AAA domain^34-176^E:3.7e-07,PF00270.29^DEAD^DEAD/DEAH box helicase^37-185^E:3.4e-07,NA,NA,NA,,
yes,AD,DHX,DN5073_c0_g1_i9,DN5073_c0_g1,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,DHX40_HUMAN,Probable ATP-dependent RNA helicase DHX40,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,KEGG:hsa:79665`KO:K18711,COG1643^helicase,PF13401.6^AAA_22^AAA domain^34-176^E:3.4e-06,PF00270.29^DEAD^DEAD/DEAH box helicase^38-185^E:3.2e-06,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^232-367^E:8.3e-14,PF04408.23^HA2^Helicase associated domain (HA2)^430-512^E:3.2e-15,NA,,
yes,AD,DHX,DN5073_c0_g1_i7,DN5073_c0_g1,DHX40_MOUSE,Probable ATP-dependent RNA helicase DHX40,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",NA,.,NA,NA,NA,NA,KEGG:mmu:67487`KO:K18711,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN55170_c0_g1_i1,DN55170_c0_g1,DHX58_HUMAN,Probable ATP-dependent RNA helicase DHX58,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,.,NA,NA,NA,NA,KEGG:hsa:79132`KO:K12649,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN28173_c0_g1_i1,DN28173_c0_g1,DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:rno:310461`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i23,DN1316_c0_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:hsa:170506`KO:K14442,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^85-173^E:9.1e-21,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^246-332^E:1.6e-17,NA,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i16,DN1316_c0_g1,DHX36_MOUSE,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:rno:310461`KO:K14442,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^268-426^E:5.3e-14,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^529-660^E:2.7e-16,PF04408.23^HA2^Helicase associated domain (HA2)^724-787^E:4.6e-18,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i20,DN1316_c0_g1,DHX36_MOUSE,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:rno:310461`KO:K14442,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^268-426^E:8.2e-14,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^529-660^E:4.1e-16,PF04408.23^HA2^Helicase associated domain (HA2)^724-812^E:3.5e-20,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^885-971^E:5.9e-17,NA,,
yes,AD,DHX,DN1316_c0_g1_i15,DN1316_c0_g1,DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_RAT,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:rno:310461`KO:K14442,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^268-426^E:6.2e-14,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^529-660^E:3.1e-16,PF04408.23^HA2^Helicase associated domain (HA2)^724-812^E:2.7e-20,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i1,DN1316_c0_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:hsa:170506`KO:K14442,COG1643^helicase,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^6-92^E:2.9e-18,NA,NA,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i10,DN1316_c0_g1,DHX36_MOUSE,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_BOVIN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:bta:509583`KO:K14442,COG1643^helicase,PF00270.29^DEAD^DEAD/DEAH box helicase^164-322^E:2.3e-14,NA,NA,NA,NA,,
yes,AD,DHX,DN1316_c0_g1_i12,DN1316_c0_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,KEGG:hsa:170506`KO:K14442,COG1643^helicase,PF04408.23^HA2^Helicase associated domain (HA2)^85-173^E:9.1e-21,PF07717.16^OB_NTP_bind^Oligonucleotide/oligosaccharide-binding (OB)-fold^246-332^E:1.6e-17,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g1_i10,DN26506_c0_g1,ADHX_BOVIN,Alcohol dehydrogenase class-3 {ECO:0000250|UniProtKB:P11766},.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0005504^molecular_function^fatty acid binding,GO:0018467^molecular_function^formaldehyde dehydrogenase activity,.,NA,NA,NA,NA,KEGG:bta:505515`KO:K00121,COG1062^alcohol dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g1_i8,DN26506_c0_g1,ADHX_BOVIN,Alcohol dehydrogenase class-3 {ECO:0000250|UniProtKB:P11766},.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0005504^molecular_function^fatty acid binding,GO:0018467^molecular_function^formaldehyde dehydrogenase activity,.,NA,NA,NA,NA,KEGG:bta:505515`KO:K00121,COG1062^alcohol dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g3_i3,DN26506_c0_g3,ADHX_SAAHA,Alcohol dehydrogenase class-3,ADHX_SAAHA,Alcohol dehydrogenase class-3,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,.,.,PF00107.26^ADH_zinc_N^Zinc-binding dehydrogenase^80-149^E:7.8e-18,NA,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g3_i4,DN26506_c0_g3,ADHX_MOUSE,Alcohol dehydrogenase class-3 {ECO:0000305},ADHX_MOUSE,Alcohol dehydrogenase class-3 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,KEGG:mmu:11532`KO:K00121,COG1062^alcohol dehydrogenase,PF00107.26^ADH_zinc_N^Zinc-binding dehydrogenase^117-208^E:1.3e-19,NA,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g3_i5,DN26506_c0_g3,ADHX_SAAHA,Alcohol dehydrogenase class-3,ADHX_SAAHA,Alcohol dehydrogenase class-3,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,.,.,PF08240.12^ADH_N^Alcohol dehydrogenase GroES-like domain^44-165^E:5e-24,PF00107.26^ADH_zinc_N^Zinc-binding dehydrogenase^213-342^E:1.2e-25,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g3_i1,DN26506_c0_g3,ADHX_HUMAN,Alcohol dehydrogenase class-3 {ECO:0000305},ADHX_HUMAN,Alcohol dehydrogenase class-3 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005739^cellular_component^mitochondrion,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0009055^molecular_function^electron transfer activity,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005739^cellular_component^mitochondrion,"GO:0004024^molecular_function^alcohol dehydrogenase activity, zinc-dependent",GO:0009055^molecular_function^electron transfer activity,KEGG:hsa:128`KO:K00121,COG1062^alcohol dehydrogenase,PF08240.12^ADH_N^Alcohol dehydrogenase GroES-like domain^44-100^E:2e-15,NA,NA,NA,NA,,
no,AD,DHX,DN26506_c0_g3_i2,DN26506_c0_g3,ADHX_SAAHA,Alcohol dehydrogenase class-3,ADHX_SAAHA,Alcohol dehydrogenase class-3,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,GO:0005737^cellular_component^cytoplasm,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,GO:0051903^molecular_function^S-(hydroxymethyl)glutathione dehydrogenase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006069^biological_process^ethanol oxidation,.,.,PF00107.26^ADH_zinc_N^Zinc-binding dehydrogenase^80-209^E:4.5e-26,NA,NA,NA,NA,,
yes,AD,DHX,DN64924_c1_g1_i1,DN64924_c1_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN108695_c1_g1_i1,DN108695_c1_g1,DHX9_PONAB,ATP-dependent RNA helicase A {ECO:0000250|UniProtKB:Q08211},.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005813^cellular_component^centrosome,GO:0070937^cellular_component^CRD-mediated mRNA stability complex,GO:0005737^cellular_component^cytoplasm,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,.,NA,NA,NA,NA,KEGG:pon:100449914`KO:K13184,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN192193_c0_g1_i1,DN192193_c0_g1,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:57647`KO:K14780,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN105335_c0_g1_i1,DN105335_c0_g1,DHX32_HUMAN,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,DHX32_HUMAN,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:55760`KO:K18994,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN128096_c0_g1_i1,DN128096_c0_g1,DHX57_HUMAN,Putative ATP-dependent RNA helicase DHX57,.,NA,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,NA,.,NA,NA,NA,NA,KEGG:hsa:90957`KO:K13026,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN161550_c0_g1_i1,DN161550_c0_g1,DHX29_HUMAN,ATP-dependent RNA helicase DHX29 {ECO:0000255|HAMAP-Rule:MF_03068},.,NA,GO:0016282^cellular_component^eukaryotic 43S preinitiation complex,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0045296^molecular_function^cadherin binding,GO:0043024^molecular_function^ribosomal small subunit binding,.,NA,NA,NA,NA,KEGG:hsa:54505`KO:K18995,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DHX,DN112476_c0_g1_i2,DN112476_c0_g1,NNRE_XENTR,NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005739^cellular_component^mitochondrion,GO:0046872^molecular_function^metal ion binding,GO:0052856^molecular_function^NADHX epimerase activity,GO:0052857^molecular_function^NADPHX epimerase activity,.,NA,NA,NA,NA,.,COG0062^NADHX epimerase activity,.,NA,NA,NA,NA,,
yes,AD,DHX,DN119405_c0_g1_i1,DN119405_c0_g1,DHX8_MOUSE,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,.,NA,NA,NA,NA,KEGG:mmu:217207`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN162640_c0_g1_i1,DN162640_c0_g1,DHX32_HUMAN,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,DHX32_HUMAN,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:55760`KO:K18994,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN177553_c0_g1_i1,DN177553_c0_g1,DHX33_HUMAN,ATP-dependent RNA helicase DHX33 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0072559^cellular_component^NLRP3 inflammasome complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:56919`KO:K17820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN124208_c2_g1_i1,DN124208_c2_g1,DHX36_HUMAN,ATP-dependent DNA/RNA helicase DHX36 {ECO:0000305},.,NA,GO:0030424^cellular_component^axon,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005737^cellular_component^cytoplasm,GO:0010494^cellular_component^cytoplasmic stress granule,GO:0005829^cellular_component^cytosol,.,NA,NA,NA,NA,KEGG:hsa:170506`KO:K14442,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN159595_c0_g1_i1,DN159595_c0_g1,DHX58_MOUSE,Probable ATP-dependent RNA helicase DHX58,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0003724^molecular_function^RNA helicase activity,.,NA,NA,NA,NA,KEGG:mmu:80861`KO:K12649,COG1111^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN138619_c2_g1_i1,DN138619_c2_g1,DHX30_CHICK,ATP-dependent RNA helicase DHX30 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:gga:420376`KO:K13185,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN178290_c0_g1_i1,DN178290_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,.,NA,NA,NA,NA,KEGG:pon:100172442`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN239364_c0_g1_i1,DN239364_c0_g1,DHX15_PONAB,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 {ECO:0000250|UniProtKB:O43143},.,NA,GO:0005730^cellular_component^nucleolus,GO:0005524^molecular_function^ATP binding,GO:0003676^molecular_function^nucleic acid binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,.,NA,NA,NA,NA,KEGG:pon:100174435`KO:K12820,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN232589_c0_g1_i1,DN232589_c0_g1,DHX8_HUMAN,ATP-dependent RNA helicase DHX8,.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,.,NA,NA,NA,NA,KEGG:hsa:1659`KO:K12818,COG1185^Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)`COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN213118_c0_g1_i1,DN213118_c0_g1,DHX16_HUMAN,Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005681^cellular_component^spliceosomal complex,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0034458^molecular_function^3'-5' RNA helicase activity,.,NA,NA,NA,NA,KEGG:hsa:8449`KO:K12813,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DHX,DN261559_c0_g1_i1,DN261559_c0_g1,ADHX_MOUSE,Alcohol dehydrogenase class-3 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0004022^molecular_function^alcohol dehydrogenase (NAD) activity,.,NA,NA,NA,NA,KEGG:mmu:11532`KO:K00121,COG1062^alcohol dehydrogenase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN328806_c0_g1_i1,DN328806_c0_g1,DHX32_MOUSE,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:mmu:101437`KO:K18994,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN310435_c0_g1_i1,DN310435_c0_g1,DHX37_HUMAN,Probable ATP-dependent RNA helicase DHX37,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:57647`KO:K14780,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN318117_c0_g1_i1,DN318117_c0_g1,DHX32_MOUSE,Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0034458^molecular_function^3'-5' RNA helicase activity,GO:0005524^molecular_function^ATP binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:mmu:101437`KO:K18994,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN420267_c0_g1_i1,DN420267_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,.,NA,NA,NA,NA,KEGG:pon:100172442`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
yes,AD,DHX,DN468979_c0_g1_i1,DN468979_c0_g1,DHX35_PONAB,Probable ATP-dependent RNA helicase DHX35,.,NA,GO:0005681^cellular_component^spliceosomal complex,GO:0005524^molecular_function^ATP binding,GO:0003724^molecular_function^RNA helicase activity,GO:0006397^biological_process^mRNA processing,GO:0008380^biological_process^RNA splicing,.,NA,NA,NA,NA,KEGG:pon:100172442`KO:K13117,COG1643^helicase,.,NA,NA,NA,NA,,
no,AD,DRA,DN19796_c0_g1_i5,DN19796_c0_g1,ACON_RAT,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:rno:79250`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i18,DN18996_c0_g1,FGGY_HUMAN,FGGY carbohydrate kinase domain-containing protein,.,NA,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,.,NA,NA,NA,NA,KEGG:hsa:55277,COG1069^ribulokinase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i3,DN18996_c0_g1,FGGY_HUMAN,FGGY carbohydrate kinase domain-containing protein,.,NA,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,.,NA,NA,NA,NA,KEGG:hsa:55277,COG1069^ribulokinase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i10,DN18996_c0_g1,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,KEGG:mmu:75578,COG1069^ribulokinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^11-267^E:2.1e-27","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^290-496^E:1.4e-47",NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i6,DN18996_c0_g1,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xla:447059,.,"PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^1-55^E:3.1e-15",NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i29,DN18996_c0_g1,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xla:447059,COG1069^ribulokinase,"PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^1-206^E:5.8e-48",NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i5,DN18996_c0_g1,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,KEGG:mmu:75578,COG1069^ribulokinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^11-183^E:1.9e-23",NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i17,DN18996_c0_g1,FGGY_HUMAN,FGGY carbohydrate kinase domain-containing protein,.,NA,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,.,NA,NA,NA,NA,KEGG:hsa:55277,COG1069^ribulokinase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i4,DN18996_c0_g1,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xla:447059,.,"PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^27-92^E:7.4e-20",NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i28,DN18996_c0_g1,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,KEGG:mmu:75578,COG1069^ribulokinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^3-230^E:6.1e-17","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^253-459^E:1.1e-47",NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i27,DN18996_c0_g1,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,FGGY_XENLA,FGGY carbohydrate kinase domain-containing protein,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,GO:0016301^molecular_function^kinase activity,"GO:0016773^molecular_function^phosphotransferase activity, alcohol group as acceptor",GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xla:447059,.,"PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^27-92^E:2e-19",NA,NA,NA,NA,,
no,AD,DRA,DN18996_c0_g1_i2,DN18996_c0_g1,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,FGGY_MOUSE,FGGY carbohydrate kinase domain-containing protein,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,GO:0005623^cellular_component^cell,GO:0019150^molecular_function^D-ribulokinase activity,GO:0046835^biological_process^carbohydrate phosphorylation,GO:0070050^biological_process^neuron cellular homeostasis,GO:0019321^biological_process^pentose metabolic process,KEGG:mmu:75578,COG1069^ribulokinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^11-267^E:2.1e-27","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^290-496^E:1.4e-47",NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i13,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^17-146^E:7.3e-08,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i1,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i10,DN10878_c0_g1,VNN3_HUMAN,Vascular non-inflammatory molecule 3,VNN3_HUMAN,Vascular non-inflammatory molecule 3,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,KEGG:hsa:55350`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^56-285^E:5.7e-20,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i8,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^27-194^E:2.8e-12,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i11,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^17-146^E:6.1e-08,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i3,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN3_HUMAN,Vascular non-inflammatory molecule 3,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,KEGG:hsa:55350`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^56-179^E:8.5e-14,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i2,DN10878_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^27-194^E:3.3e-12,NA,NA,NA,NA,,
no,AD,DRA,DN10878_c0_g1_i7,DN10878_c0_g1,VNN3_MOUSE,Vascular non-inflammatory molecule 3,VNN3_MOUSE,Vascular non-inflammatory molecule 3,GO:0031225^cellular_component^anchored component of membrane,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,GO:0031225^cellular_component^anchored component of membrane,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,KEGG:mmu:26464`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN26043_c0_g1_i1,DN26043_c0_g1,HACD2_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:201562`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN2095_c1_g1_i1,DN2095_c1_g1,ECHA_RAT,"Trifunctional enzyme subunit alpha, mitochondrial",.,NA,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,.,NA,NA,NA,NA,KEGG:rno:170670`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1126_c0_g1_i12,DN1126_c0_g1,CHST7_MOUSE,Carbohydrate sulfotransferase 7,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0008459^molecular_function^chondroitin 6-sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:mmu:60322`KO:K04743,ENOG4111DKG^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN1126_c0_g1_i11,DN1126_c0_g1,CHST7_MOUSE,Carbohydrate sulfotransferase 7,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0008459^molecular_function^chondroitin 6-sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:mmu:60322`KO:K04743,ENOG4111DKG^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i1,DN6965_c1_g2,AUHM_MOUSE,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,NA,NA,NA,NA,KEGG:mmu:11992`KO:K05607,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i6,DN6965_c1_g2,AUHM_MOUSE,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,NA,NA,NA,NA,KEGG:mmu:11992`KO:K05607,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i3,DN6965_c1_g2,AUHM_MOUSE,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,NA,NA,NA,NA,KEGG:mmu:11992`KO:K05607,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i8,DN6965_c1_g2,AUHM_RAT,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,NA,NA,NA,NA,.,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i2,DN6965_c1_g2,AUHM_RAT,"Methylglutaconyl-CoA hydratase, mitochondrial",AUHM_RAT,"Methylglutaconyl-CoA hydratase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^89-225^E:1.7e-33,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^95-220^E:4.7e-23,NA,NA,NA,,
no,AD,DRA,DN6965_c1_g2_i4,DN6965_c1_g2,AUHM_MOUSE,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,GO:0003730^molecular_function^mRNA 3'-UTR binding,.,NA,NA,NA,NA,KEGG:mmu:11992`KO:K05607,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6931_c0_g1_i2,DN6931_c0_g1,HEM2_MACFA,Delta-aminolevulinic acid dehydratase,.,NA,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN6931_c0_g1_i1,DN6931_c0_g1,HEM2_MACFA,Delta-aminolevulinic acid dehydratase,HEM2_MACFA,Delta-aminolevulinic acid dehydratase,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,.,.,PF00490.21^ALAD^Delta-aminolevulinic acid dehydratase^11-326^E:5.4e-126,NA,NA,NA,NA,,
no,AD,DRA,DN6931_c0_g1_i3,DN6931_c0_g1,HEM2_MACFA,Delta-aminolevulinic acid dehydratase,.,NA,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN6933_c0_g1_i3,DN6933_c0_g1,NSDHL_HUMAN,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",NSDHL_MOUSE,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,KEGG:mmu:18194`KO:K07748,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6933_c0_g1_i8,DN6933_c0_g1,NSDHL_HUMAN,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:hsa:50814`KO:K07748,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN6933_c0_g1_i2,DN6933_c0_g1,NSDHL_HUMAN,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",NSDHL_MOUSE,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,KEGG:mmu:18194`KO:K07748,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^12-260^E:5.7e-13,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^13-228^E:3.4e-36,PF05368.13^NmrA^NmrA-like family^13-116^E:1.2e-06,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^14-264^E:2.5e-69,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^14-227^E:1.3e-17",,
no,AD,DRA,DN6933_c0_g1_i7,DN6933_c0_g1,NSDHL_HUMAN,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",NSDHL_MOUSE,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,KEGG:mmu:18194`KO:K07748,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^12-260^E:5.7e-13,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^13-228^E:3.4e-36,PF05368.13^NmrA^NmrA-like family^13-116^E:1.2e-06,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^14-264^E:2.5e-69,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^14-227^E:1.3e-17",,
no,AD,DRA,DN42622_c2_g1_i1,DN42622_c2_g1,ECHD2_HUMAN,"Enoyl-CoA hydratase domain-containing protein 2, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:55268,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i9,DN24590_c0_g1,BUP1_MOUSE,Beta-ureidopropionase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0008270^molecular_function^zinc ion binding,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,.,NA,NA,NA,NA,KEGG:mmu:103149`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i15,DN24590_c0_g1,BUP1_RAT,Beta-ureidopropionase,BUP1_HUMAN,Beta-ureidopropionase,GO:0005737^cellular_component^cytoplasm,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0008270^molecular_function^zinc ion binding,GO:0019483^biological_process^beta-alanine biosynthetic process,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,KEGG:hsa:51733`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^1-97^E:4.1e-25,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i11,DN24590_c0_g1,BUP1_MOUSE,Beta-ureidopropionase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0008270^molecular_function^zinc ion binding,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,.,NA,NA,NA,NA,KEGG:mmu:103149`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i17,DN24590_c0_g1,BUP1_HUMAN,Beta-ureidopropionase,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,.,NA,NA,NA,NA,KEGG:hsa:51733`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i4,DN24590_c0_g1,BUP1_HUMAN,Beta-ureidopropionase,BUP1_HUMAN,Beta-ureidopropionase,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,KEGG:hsa:51733`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^72-291^E:3.7e-51,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i12,DN24590_c0_g1,BUP1_HUMAN,Beta-ureidopropionase,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,.,NA,NA,NA,NA,KEGG:hsa:51733`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN24590_c0_g1_i1,DN24590_c0_g1,BUP1_PONAB,Beta-ureidopropionase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0003837^molecular_function^beta-ureidopropionase activity,GO:0033396^biological_process^beta-alanine biosynthetic process via 3-ureidopropionate,GO:0051260^biological_process^protein homooligomerization,GO:0046135^biological_process^pyrimidine nucleoside catabolic process,.,NA,NA,NA,NA,KEGG:pon:100172385`KO:K01431,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN15511_c0_g1_i4,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^37-291^E:3.7e-74,PF00041.21^fn3^Fibronectin type III domain^313-399^E:5.9e-12,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^885-1125^E:2e-86,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1183-1415^E:3.7e-59,NA,,
no,AD,DRA,DN15511_c0_g1_i13,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^37-291^E:3.7e-74,PF00041.21^fn3^Fibronectin type III domain^313-399^E:5.9e-12,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^878-1118^E:2e-86,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1176-1408^E:3.6e-59,NA,,
no,AD,DRA,DN15511_c0_g1_i24,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1-42^E:9.6e-09,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^100-332^E:2.2e-60,NA,NA,NA,,
no,AD,DRA,DN15511_c0_g1_i2,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1-121^E:1.8e-30,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^149-205^E:3.1e-17,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^263-495^E:5.7e-60,NA,NA,,
no,AD,DRA,DN15511_c0_g1_i16,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1-177^E:6.9e-56,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^235-467^E:5e-60,NA,NA,NA,,
no,AD,DRA,DN15511_c0_g1_i25,DN15511_c0_g1,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^37-291^E:7.4e-74,PF00041.21^fn3^Fibronectin type III domain^313-399^E:1e-11,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1754-1938^E:7.6e-61,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1966-2022^E:1.8e-16,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^2080-2312^E:7.2e-59,,
no,AD,DRA,DN15511_c0_g5_i1,DN15511_c0_g5,PTPRZ_HUMAN,Receptor-type tyrosine-protein phosphatase zeta,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0072534^cellular_component^perineuronal net,GO:0005886^cellular_component^plasma membrane,GO:0045202^cellular_component^synapse,.,NA,NA,NA,NA,KEGG:hsa:5803`KO:K08114,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,.,NA,NA,NA,NA,,
no,AD,DRA,DN891_c0_g3_i1,DN891_c0_g3,MTNB_DANRE,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:dre:447941`KO:K08964,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DRA,DN5143_c3_g1_i2,DN5143_c3_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^151-386^E:1.2e-68,NA,NA,NA,NA,,
no,AD,DRA,DN5143_c3_g1_i1,DN5143_c3_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^156-391^E:1.2e-68,NA,NA,NA,NA,,
no,AD,DRA,DN5138_c0_g1_i2,DN5138_c0_g1,CAH4_BOVIN,Carbonic anhydrase 4,CAH4_BOVIN,Carbonic anhydrase 4,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,KEGG:bta:280741`KO:K18246,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^23-287^E:4e-92,NA,NA,NA,NA,,
no,AD,DRA,DN5138_c0_g1_i5,DN5138_c0_g1,CAH4_BOVIN,Carbonic anhydrase 4,CAH4_BOVIN,Carbonic anhydrase 4,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,KEGG:bta:280741`KO:K18246,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^23-147^E:1.3e-38,NA,NA,NA,NA,,
no,AD,DRA,DN5138_c0_g1_i3,DN5138_c0_g1,CAH4_BOVIN,Carbonic anhydrase 4,CAH4_BOVIN,Carbonic anhydrase 4,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,KEGG:bta:280741`KO:K18246,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^23-182^E:2.9e-52,NA,NA,NA,NA,,
no,AD,DRA,DN4273_c0_g1_i4,DN4273_c0_g1,ECHM_MOUSE,"Enoyl-CoA hydratase, mitochondrial",ECHM_RAT,"Enoyl-CoA hydratase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,KEGG:rno:100911186`KEGG:rno:140547`KO:K07511,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^60-111^E:6.1e-14,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^63-111^E:4.4e-08,NA,NA,NA,,
no,AD,DRA,DN4273_c0_g1_i1,DN4273_c0_g1,ECHM_MOUSE,"Enoyl-CoA hydratase, mitochondrial",ECHM_RAT,"Enoyl-CoA hydratase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,KEGG:rno:100911186`KEGG:rno:140547`KO:K07511,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^60-165^E:2.9e-31,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^63-155^E:5.6e-15,NA,NA,NA,,
no,AD,DRA,DN4273_c0_g1_i5,DN4273_c0_g1,ECHM_MOUSE,"Enoyl-CoA hydratase, mitochondrial",ECHM_MOUSE,"Enoyl-CoA hydratase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,KEGG:mmu:93747`KO:K07511,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^60-305^E:4.8e-94,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^63-234^E:1.3e-32,NA,NA,NA,,
no,AD,DRA,DN14754_c0_g2_i1,DN14754_c0_g2,FUMH_MACFA,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",FUMH_MACFA,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,.,PF00206.20^Lyase_1^Lyase^57-388^E:3e-123,PF10415.9^FumaraseC_C^Fumarase C C-terminus^454-506^E:3e-27,NA,NA,NA,,
no,AD,DRA,DN14754_c0_g2_i4,DN14754_c0_g2,FUMH_MACFA,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",FUMH_MACFA,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,.,PF00206.20^Lyase_1^Lyase^57-369^E:2.8e-111,NA,NA,NA,NA,,
no,AD,DRA,DN14754_c0_g2_i5,DN14754_c0_g2,FUMH_RAT,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:rno:24368`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN14754_c0_g2_i2,DN14754_c0_g2,FUMH_RAT,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:rno:24368`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN13902_c0_g1_i2,DN13902_c0_g1,SDSL_MOUSE,Serine dehydratase-like,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0042802^molecular_function^identical protein binding,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0006565^biological_process^L-serine catabolic process,.,NA,NA,NA,NA,KEGG:mmu:257635`KO:K17989,COG1171^Threonine dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13902_c0_g1_i6,DN13902_c0_g1,SDSL_MOUSE,Serine dehydratase-like,SDSL_MOUSE,Serine dehydratase-like,GO:0005739^cellular_component^mitochondrion,GO:0042802^molecular_function^identical protein binding,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0006565^biological_process^L-serine catabolic process,GO:0005739^cellular_component^mitochondrion,GO:0042802^molecular_function^identical protein binding,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0006565^biological_process^L-serine catabolic process,KEGG:mmu:257635`KO:K17989,COG1171^Threonine dehydratase,PF00291.25^PALP^Pyridoxal-phosphate dependent enzyme^10-303^E:1.4e-74,NA,NA,NA,NA,,
no,AD,DRA,DN13902_c0_g1_i1,DN13902_c0_g1,SDSL_HUMAN,Serine dehydratase-like,SDSL_MOUSE,Serine dehydratase-like,GO:0005829^cellular_component^cytosol,GO:0042802^molecular_function^identical protein binding,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0005739^cellular_component^mitochondrion,GO:0042802^molecular_function^identical protein binding,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0006565^biological_process^L-serine catabolic process,KEGG:mmu:257635`KO:K17989,COG1171^Threonine dehydratase,PF00291.25^PALP^Pyridoxal-phosphate dependent enzyme^14-114^E:7.9e-30,NA,NA,NA,NA,,
no,AD,DRA,DN54788_c0_g1_i1,DN54788_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,.,NA,NA,NA,NA,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN87254_c0_g1_i1,DN87254_c0_g1,NIT1_MOUSE,Deaminated glutathione amidase {ECO:0000303|PubMed:28373563},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005739^cellular_component^mitochondrion,"GO:0016811^molecular_function^hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides",GO:0006807^biological_process^nitrogen compound metabolic process,NA,.,NA,NA,NA,NA,KEGG:mmu:27045`KO:K11206,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN20300_c1_g1_i1,DN20300_c1_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN20300_c1_g1_i2,DN20300_c1_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN20300_c1_g3_i1,DN20300_c1_g3,HACD3_BOVIN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 {ECO:0000305},HACD3_BOVIN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:bta:100125237`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN20300_c2_g1_i1,DN20300_c2_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN53889_c1_g1_i1,DN53889_c1_g1,CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,KEGG:pon:100172009`KO:K18588,COG2867^Cyclase dehydrase,PF03364.20^Polyketide_cyc^Polyketide cyclase / dehydrase and lipid transport^79-175^E:2.5e-05,NA,NA,NA,NA,,
no,AD,DRA,DN3660_c0_g1_i7,DN3660_c0_g1,CHSTA_CHICK,Carbohydrate sulfotransferase 10,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0030166^biological_process^proteoglycan biosynthetic process,.,NA,NA,NA,NA,KEGG:gga:395206`KO:K09674,ENOG4111GJR^carbohydrate,.,NA,NA,NA,NA,,
no,AD,DRA,DN3660_c0_g1_i12,DN3660_c0_g1,CHSTA_CHICK,Carbohydrate sulfotransferase 10,CHSTA_CHICK,Carbohydrate sulfotransferase 10,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0030166^biological_process^proteoglycan biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0030166^biological_process^proteoglycan biosynthetic process,KEGG:gga:395206`KO:K09674,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^118-354^E:3.7e-51,NA,NA,NA,NA,,
no,AD,DRA,DN3660_c0_g1_i4,DN3660_c0_g1,CHSTA_CHICK,Carbohydrate sulfotransferase 10,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0030166^biological_process^proteoglycan biosynthetic process,.,NA,NA,NA,NA,KEGG:gga:395206`KO:K09674,ENOG4111GJR^carbohydrate,.,NA,NA,NA,NA,,
no,AD,DRA,DN3607_c1_g1_i2,DN3607_c1_g1,NIT2_BOVIN,Omega-amidase NIT2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,.,NA,NA,NA,NA,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN3607_c1_g1_i3,DN3607_c1_g1,NIT2_BOVIN,Omega-amidase NIT2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,.,NA,NA,NA,NA,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN3607_c1_g1_i4,DN3607_c1_g1,NIT2_BOVIN,Omega-amidase NIT2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,.,NA,NA,NA,NA,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2796_c1_g1_i1,DN2796_c1_g1,ECH1_MOUSE,"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,"GO:0051750^molecular_function^delta3,5-delta2,4-dienoyl-CoA isomerase activity",GO:0006635^biological_process^fatty acid beta-oxidation,NA,.,NA,NA,NA,NA,KEGG:mmu:51798`KO:K12663,ENOG410XTHX^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN16971_c0_g1_i2,DN16971_c0_g1,NDUA9_BOVIN,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",NDUA9_BOVIN,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0044877^molecular_function^protein-containing complex binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0044877^molecular_function^protein-containing complex binding,KEGG:bta:404188`KO:K03953,COG0702^epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN16971_c0_g1_i12,DN16971_c0_g1,NDUA9_GORGO,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",NDUA9_RAT,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0050662^molecular_function^coenzyme binding,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0032981^biological_process^mitochondrial respiratory chain complex I assembly,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,KEGG:rno:362440`KO:K03953,COG0702^epimerase dehydratase,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^40-114^E:2e-05,PF05368.13^NmrA^NmrA-like family^40-114^E:9.2e-05,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^41-113^E:2.8e-05,NA,NA,,
no,AD,DRA,DN16971_c0_g1_i9,DN16971_c0_g1,NDUA9_BOVIN,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",NDUA9_BOVIN,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0044877^molecular_function^protein-containing complex binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0044877^molecular_function^protein-containing complex binding,KEGG:bta:404188`KO:K03953,COG0702^epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN16971_c0_g1_i1,DN16971_c0_g1,NDUA9_GORGO,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",NDUA9_RAT,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0050662^molecular_function^coenzyme binding,GO:0003954^molecular_function^NADH dehydrogenase activity,GO:0032981^biological_process^mitochondrial respiratory chain complex I assembly,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,KEGG:rno:362440`KO:K03953,COG0702^epimerase dehydratase,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^49-123^E:2.4e-05,PF05368.13^NmrA^NmrA-like family^49-123^E:0.00011,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^50-121^E:3.4e-05,NA,NA,,
no,AD,DRA,DN16971_c0_g1_i14,DN16971_c0_g1,NDUA9_PANTR,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005654^cellular_component^nucleoplasm,GO:0050662^molecular_function^coenzyme binding,GO:0003954^molecular_function^NADH dehydrogenase activity,.,NA,NA,NA,NA,KEGG:ptr:451766`KO:K03953,COG0702^epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i3,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i4,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^54-153^E:2.3e-35",NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i5,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^54-214^E:2.2e-50",NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i12,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^65-130^E:1.5e-18",NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i7,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i6,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^159-224^E:4.8e-18",NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i10,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN8509_c0_g1_i11,DN8509_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^61-126^E:1.4e-18",NA,NA,NA,NA,,
no,AD,DRA,DN6730_c0_g2_i2,DN6730_c0_g2,NMRL1_CHICK,NmrA-like family domain-containing protein 1,NMRL1_CHICK,NmrA-like family domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0001081^biological_process^nitrogen catabolite repression of transcription from RNA polymerase II promoter,NA,NA,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0001081^biological_process^nitrogen catabolite repression of transcription from RNA polymerase II promoter,NA,NA,KEGG:gga:416672,COG0702^epimerase dehydratase,PF05368.13^NmrA^NmrA-like family^33-180^E:7.4e-27,NA,NA,NA,NA,,
no,AD,DRA,DN6730_c0_g2_i1,DN6730_c0_g2,NMRL1_CHICK,NmrA-like family domain-containing protein 1,NMRL1_CHICK,NmrA-like family domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0001081^biological_process^nitrogen catabolite repression of transcription from RNA polymerase II promoter,NA,NA,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0001081^biological_process^nitrogen catabolite repression of transcription from RNA polymerase II promoter,NA,NA,KEGG:gga:416672,COG0702^epimerase dehydratase,PF05368.13^NmrA^NmrA-like family^44-273^E:8.1e-52,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^44-106^E:9.4e-05,PF13460.6^NAD_binding_10^NAD(P)H-binding^47-189^E:1.8e-11,NA,NA,,
no,AD,DRA,DN6721_c0_g1_i7,DN6721_c0_g1,IP3KA_HUMAN,Inositol-trisphosphate 3-kinase A,CHST8_MOUSE,Carbohydrate sulfotransferase 8,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0005524^molecular_function^ATP binding,GO:0005516^molecular_function^calmodulin binding,GO:0004683^molecular_function^calmodulin-dependent protein kinase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:68947`KO:K09672,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^75-302^E:1.8e-44,NA,NA,NA,NA,,
no,AD,DRA,DN6721_c0_g1_i9,DN6721_c0_g1,IP3KA_HUMAN,Inositol-trisphosphate 3-kinase A,CHST8_MOUSE,Carbohydrate sulfotransferase 8,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0005524^molecular_function^ATP binding,GO:0005516^molecular_function^calmodulin binding,GO:0004683^molecular_function^calmodulin-dependent protein kinase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:68947`KO:K09672,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^75-302^E:1.8e-44,NA,NA,NA,NA,,
no,AD,DRA,DN6721_c0_g1_i8,DN6721_c0_g1,IP3KA_HUMAN,Inositol-trisphosphate 3-kinase A,CHST9_MOUSE,Carbohydrate sulfotransferase 9,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0005524^molecular_function^ATP binding,GO:0005516^molecular_function^calmodulin binding,GO:0004683^molecular_function^calmodulin-dependent protein kinase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:71367`KO:K09673,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^11-174^E:8.3e-35,NA,NA,NA,NA,,
no,AD,DRA,DN6721_c0_g1_i2,DN6721_c0_g1,IP3KA_HUMAN,Inositol-trisphosphate 3-kinase A,CHST9_MOUSE,Carbohydrate sulfotransferase 9,GO:0005829^cellular_component^cytosol,GO:0043197^cellular_component^dendritic spine,GO:0005524^molecular_function^ATP binding,GO:0005516^molecular_function^calmodulin binding,GO:0004683^molecular_function^calmodulin-dependent protein kinase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:71367`KO:K09673,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^11-174^E:8.3e-35,NA,NA,NA,NA,,
no,AD,DRA,DN6754_c0_g1_i2,DN6754_c0_g1,ECHP_PONAB,Peroxisomal bifunctional enzyme,ECHP_HUMAN,Peroxisomal bifunctional enzyme,GO:0005777^cellular_component^peroxisome,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0005829^cellular_component^cytosol,GO:0005782^cellular_component^peroxisomal matrix,GO:0005777^cellular_component^peroxisome,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,KEGG:hsa:1962`KO:K07514,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^8-188^E:1.7e-41,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^13-180^E:4.2e-28,"PF02737.18^3HCDH_N^3-hydroxyacyl-CoA dehydrogenase, NAD binding domain^300-478^E:6.3e-53","PF00725.22^3HCDH^3-hydroxyacyl-CoA dehydrogenase, C-terminal domain^481-585^E:5.1e-25","PF00725.22^3HCDH^3-hydroxyacyl-CoA dehydrogenase, C-terminal domain^622-711^E:2.1e-05",,
no,AD,DRA,DN23339_c0_g1_i1,DN23339_c0_g1,HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:mmu:30963`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^79-133^E:4.9e-13",NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g1_i9,DN23339_c0_g1,HACD1_SHEEP,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:oas:443484`KO:K10703,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g1_i5,DN23339_c0_g1,HACD1_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:9200`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g1_i10,DN23339_c0_g1,HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:mmu:30963`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^79-133^E:3.4e-09",NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g1_i4,DN23339_c0_g1,HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},HACD1_MOUSE,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:mmu:30963`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^79-135^E:5.3e-13",NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g1_i7,DN23339_c0_g1,HACD1_SHEEP,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:oas:443484`KO:K10703,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN23339_c0_g2_i1,DN23339_c0_g2,HACD1_CANLF,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:cfa:574011`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i1,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^10-200^E:1.3e-70,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i6,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^24-86^E:1.6e-16,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i3,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^46-167^E:9.9e-36,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i2,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^35-293^E:2.9e-93,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i4,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^42-300^E:3e-93,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i5,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^35-256^E:2e-82,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g1_i7,DN14286_c0_g1,CAH15_MOUSE,Carbonic anhydrase 15,CAH15_MOUSE,Carbonic anhydrase 15,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^24-282^E:9.9e-94,NA,NA,NA,NA,,
no,AD,DRA,DN14286_c0_g2_i3,DN14286_c0_g2,CAH4_RABIT,Carbonic anhydrase 4,CAH15_MOUSE,Carbonic anhydrase 15,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:80733`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^35-97^E:5.5e-16,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i5,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,TM231_CHICK,Transmembrane protein 231,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0060170^cellular_component^ciliary membrane,GO:0035869^cellular_component^ciliary transition zone,GO:0016021^cellular_component^integral component of membrane,GO:0036038^cellular_component^MKS complex,GO:0043010^biological_process^camera-type eye development,KEGG:gga:425108`KO:K19362,"ENOG410XQ0K^Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog SHH signaling",PF10149.9^TM231^Transmembrane protein 231^1-144^E:1.1e-47,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i21,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,TM231_CHICK,Transmembrane protein 231,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0060170^cellular_component^ciliary membrane,GO:0035869^cellular_component^ciliary transition zone,GO:0016021^cellular_component^integral component of membrane,GO:0036038^cellular_component^MKS complex,GO:0043010^biological_process^camera-type eye development,KEGG:gga:425108`KO:K19362,"ENOG410XQ0K^Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog SHH signaling",PF10149.9^TM231^Transmembrane protein 231^1-144^E:1.1e-47,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i8,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,TM231_CHICK,Transmembrane protein 231,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0060170^cellular_component^ciliary membrane,GO:0035869^cellular_component^ciliary transition zone,GO:0016021^cellular_component^integral component of membrane,GO:0036038^cellular_component^MKS complex,GO:0043010^biological_process^camera-type eye development,KEGG:gga:425108`KO:K19362,"ENOG410XQ0K^Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog SHH signaling",PF10149.9^TM231^Transmembrane protein 231^1-253^E:7.6e-104,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i10,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,TM231_CHICK,Transmembrane protein 231,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0060170^cellular_component^ciliary membrane,GO:0035869^cellular_component^ciliary transition zone,GO:0016021^cellular_component^integral component of membrane,GO:0036038^cellular_component^MKS complex,GO:0043010^biological_process^camera-type eye development,KEGG:gga:425108`KO:K19362,"ENOG410XQ0K^Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog SHH signaling",PF10149.9^TM231^Transmembrane protein 231^1-144^E:1.1e-47,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i2,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,CHST5_MOUSE,Carbohydrate sulfotransferase 5,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:mmu:56773`KO:K09671,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^44-352^E:1.2e-25,PF13469.6^Sulfotransfer_3^Sulfotransferase family^197-297^E:5.5e-10,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i23,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,.,NA,NA,NA,NA,KEGG:mmu:56773`KO:K09671,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i1,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,TM231_CHICK,Transmembrane protein 231,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0060170^cellular_component^ciliary membrane,GO:0035869^cellular_component^ciliary transition zone,GO:0016021^cellular_component^integral component of membrane,GO:0036038^cellular_component^MKS complex,GO:0043010^biological_process^camera-type eye development,KEGG:gga:425108`KO:K19362,"ENOG410XQ0K^Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog SHH signaling",PF10149.9^TM231^Transmembrane protein 231^2-157^E:2e-54,NA,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i16,DN273_c0_g1,CHST5_HUMAN,Carbohydrate sulfotransferase 5,CHST6_HUMAN,Carbohydrate sulfotransferase 6,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031228^cellular_component^intrinsic component of Golgi membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,KEGG:hsa:4166`KO:K09671,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^58-222^E:1.5e-16,PF13469.6^Sulfotransfer_3^Sulfotransferase family^94-194^E:2.2e-10,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i15,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,CHST5_MOUSE,Carbohydrate sulfotransferase 5,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:mmu:56773`KO:K09671,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^44-352^E:1.2e-25,PF13469.6^Sulfotransfer_3^Sulfotransferase family^197-297^E:5.5e-10,NA,NA,NA,,
no,AD,DRA,DN273_c0_g1_i17,DN273_c0_g1,CHST5_MOUSE,Carbohydrate sulfotransferase 5,CHST5_MOUSE,Carbohydrate sulfotransferase 5,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:mmu:56773`KO:K09671,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^44-352^E:1.2e-25,PF13469.6^Sulfotransfer_3^Sulfotransferase family^197-297^E:5.5e-10,NA,NA,NA,,
no,AD,DRA,DN273_c0_g2_i1,DN273_c0_g2,CHST4_HUMAN,Carbohydrate sulfotransferase 4,CHST4_HUMAN,Carbohydrate sulfotransferase 4,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031228^cellular_component^intrinsic component of Golgi membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031228^cellular_component^intrinsic component of Golgi membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,KEGG:hsa:10164`KO:K04746,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^65-377^E:2e-27,PF13469.6^Sulfotransfer_3^Sulfotransferase family^66-318^E:9e-17,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i12,DN235_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i8,DN235_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i9,DN235_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i2,DN235_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i1,DN235_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235_c0_g1_i11,DN235_c0_g1,ECI1_MOUSE,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,.,NA,NA,NA,NA,KEGG:mmu:13177`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i8,DN14343_c0_g1,ACON_BOVIN,"Aconitate hydratase, mitochondrial",ACON_BOVIN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,PF00694.19^Aconitase_C^Aconitase C-terminal domain^3-60^E:1.3e-27,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i12,DN14343_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i6,DN14343_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i4,DN14343_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",ACON_HUMAN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,PF00694.19^Aconitase_C^Aconitase C-terminal domain^3-130^E:5.5e-47,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i9,DN14343_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",ACON_HUMAN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-121^E:1.6e-40,PF00694.19^Aconitase_C^Aconitase C-terminal domain^202-329^E:2.9e-46,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i11,DN14343_c0_g1,ACON_RAT,"Aconitate hydratase, mitochondrial",ACON_HUMAN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,PF00694.19^Aconitase_C^Aconitase C-terminal domain^3-130^E:5.5e-47,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i1,DN14343_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",ACON_HUMAN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,PF00694.19^Aconitase_C^Aconitase C-terminal domain^3-130^E:5.5e-47,NA,NA,NA,NA,,
no,AD,DRA,DN14343_c0_g1_i10,DN14343_c0_g1,ACON_RAT,"Aconitate hydratase, mitochondrial",ACON_RAT,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:rno:79250`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^10-376^E:6.1e-122,NA,NA,NA,NA,,
no,AD,DRA,DN81330_c0_g1_i1,DN81330_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN3108_c0_g1_i1,DN3108_c0_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^6-282^E:8.8e-48,PF02540.17^NAD_synthase^NAD synthase^339-603^E:1e-27,NA,NA,NA,,
no,AD,DRA,DN3108_c0_g1_i3,DN3108_c0_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF02540.17^NAD_synthase^NAD synthase^73-337^E:2.7e-28,NA,NA,NA,NA,,
no,AD,DRA,DN3108_c0_g1_i6,DN3108_c0_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^6-264^E:5.1e-45,NA,NA,NA,NA,,
no,AD,DRA,DN3108_c0_g1_i5,DN3108_c0_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^6-264^E:5.1e-45,NA,NA,NA,NA,,
no,AD,DRA,DN3108_c0_g1_i4,DN3108_c0_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^6-282^E:8.8e-48,PF02540.17^NAD_synthase^NAD synthase^339-603^E:1e-27,NA,NA,NA,,
no,AD,DRA,DN71587_c0_g1_i1,DN71587_c0_g1,PYGB_RAT,"Glycogen phosphorylase, brain form",.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,.,NA,NA,NA,NA,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g1_i7,DN11851_c0_g1,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g1_i3,DN11851_c0_g1,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g1_i1,DN11851_c0_g1,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,PF00596.21^Aldolase_II^Class II Aldolase and Adducin N-terminal domain^45-226^E:8.8e-45,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g1_i6,DN11851_c0_g1,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,PF00596.21^Aldolase_II^Class II Aldolase and Adducin N-terminal domain^45-238^E:6e-48,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g1_i8,DN11851_c0_g1,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,.,NA,NA,NA,NA,,
no,AD,DRA,DN11851_c0_g2_i1,DN11851_c0_g2,MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},MTNB_CHICK,Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116},GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,GO:0005737^cellular_component^cytoplasm,GO:0046570^molecular_function^methylthioribulose 1-phosphate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006915^biological_process^apoptotic process,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,KEGG:gga:428860`KO:K08964,COG0235^Class II aldolase adducin,PF00596.21^Aldolase_II^Class II Aldolase and Adducin N-terminal domain^1-82^E:1.7e-14,NA,NA,NA,NA,,
no,AD,DRA,DN8096_c1_g1_i1,DN8096_c1_g1,CHST2_MOUSE,Carbohydrate sulfotransferase 2,.,NA,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:mmu:54371`KO:K04745,ENOG4111DKG^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN8030_c1_g2_i1,DN8030_c1_g2,DRAM1_HUMAN,DNA damage-regulated autophagy modulator protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,KEGG:hsa:55332`KO:K21955,ENOG4111KNB^DNA-damage regulated autophagy modulator,.,NA,NA,NA,NA,,
no,AD,DRA,DN8089_c0_g2_i2,DN8089_c0_g2,PHS_CHICK,Pterin-4-alpha-carbinolamine dehydratase,PHS_CHICK,Pterin-4-alpha-carbinolamine dehydratase,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0042802^molecular_function^identical protein binding,GO:0004505^molecular_function^phenylalanine 4-monooxygenase activity,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0042802^molecular_function^identical protein binding,GO:0004505^molecular_function^phenylalanine 4-monooxygenase activity,KEGG:gga:395729`KO:K01724,.,PF01329.19^Pterin_4a^Pterin 4 alpha carbinolamine dehydratase^60-151^E:1.1e-30,NA,NA,NA,NA,,
no,AD,DRA,DN10012_c0_g1_i1,DN10012_c0_g1,XYLB_MOUSE,Xylulose kinase,XYLB_MOUSE,Xylulose kinase,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,KEGG:mmu:102448`KO:K00854,COG1070^Carbohydrate kinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^71-223^E:5.3e-14","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^232-415^E:1.3e-19",NA,NA,NA,,
no,AD,DRA,DN10012_c0_g1_i4,DN10012_c0_g1,XYLB_MOUSE,Xylulose kinase,XYLB_MOUSE,Xylulose kinase,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,KEGG:mmu:102448`KO:K00854,COG1070^Carbohydrate kinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^71-223^E:5.3e-14","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^232-415^E:1.3e-19",NA,NA,NA,,
no,AD,DRA,DN10012_c0_g1_i5,DN10012_c0_g1,XYLB_HUMAN,Xylulose kinase,XYLB_HUMAN,Xylulose kinase,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0042732^biological_process^D-xylose metabolic process,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0042732^biological_process^D-xylose metabolic process,KEGG:hsa:9942`KO:K00854,COG1070^Carbohydrate kinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^62-214^E:5.1e-14","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^223-406^E:1.3e-19",NA,NA,NA,,
no,AD,DRA,DN10012_c0_g1_i2,DN10012_c0_g1,XYLB_MOUSE,Xylulose kinase,XYLB_MOUSE,Xylulose kinase,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,KEGG:mmu:102448`KO:K00854,COG1070^Carbohydrate kinase,"PF00370.21^FGGY_N^FGGY family of carbohydrate kinases, N-terminal domain^155-307^E:7.3e-14","PF02782.16^FGGY_C^FGGY family of carbohydrate kinases, C-terminal domain^316-499^E:1.9e-19",NA,NA,NA,,
no,AD,DRA,DN10012_c0_g2_i1,DN10012_c0_g2,XYLB_BOVIN,Xylulose kinase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0004856^molecular_function^xylulokinase activity,GO:0042732^biological_process^D-xylose metabolic process,GO:0016310^biological_process^phosphorylation,.,NA,NA,NA,NA,KEGG:bta:515146`KO:K00854,COG1070^Carbohydrate kinase,.,NA,NA,NA,NA,,
no,AD,DRA,DN15747_c0_g1_i2,DN15747_c0_g1,PYGL_RAT,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,.,NA,NA,NA,NA,KEGG:rno:64035`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN83702_c0_g1_i1,DN83702_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN65523_c0_g1_i1,DN65523_c0_g1,ENOG_HUMAN,Gamma-enolase,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0043204^cellular_component^perikaryon,.,NA,NA,NA,NA,KEGG:hsa:2026`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN39294_c0_g1_i3,DN39294_c0_g1,NMRL1_MOUSE,NmrA-like family domain-containing protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0042802^molecular_function^identical protein binding,GO:0001081^biological_process^nitrogen catabolite repression of transcription from RNA polymerase II promoter,NA,.,NA,NA,NA,NA,KEGG:mmu:67824,COG0702^epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN9205_c0_g1_i2,DN9205_c0_g1,CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,KEGG:hsa:9425`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^53-104^E:7.9e-19,NA,NA,NA,NA,,
no,AD,DRA,DN9205_c0_g1_i5,DN9205_c0_g1,CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,KEGG:hsa:9425`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^53-104^E:1.4e-18,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^354-586^E:6.2e-32,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^354-570^E:1.8e-15,NA,NA,,
no,AD,DRA,DN9205_c0_g1_i3,DN9205_c0_g1,CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,KEGG:hsa:9425`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^208-440^E:3.1e-32,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^208-424^E:9.1e-16,NA,NA,NA,,
no,AD,DRA,DN9205_c0_g1_i4,DN9205_c0_g1,CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},CDYL_HUMAN,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,KEGG:hsa:9425`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^53-104^E:1.1e-18,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^354-491^E:1.3e-18,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^354-487^E:5.6e-12,NA,NA,,
no,AD,DRA,DN9205_c0_g1_i1,DN9205_c0_g1,CDYL_MOUSE,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},.,NA,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,.,NA,NA,NA,NA,KEGG:mmu:12593`KO:K00653,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13120_c0_g1_i1,DN13120_c0_g1,CHST9_HUMAN,Carbohydrate sulfotransferase 9,CHST9_HUMAN,Carbohydrate sulfotransferase 9,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,KEGG:hsa:83539`KO:K09673,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^173-406^E:2.8e-60,NA,NA,NA,NA,,
no,AD,DRA,DN13120_c0_g1_i3,DN13120_c0_g1,CHST9_HUMAN,Carbohydrate sulfotransferase 9,CHST9_HUMAN,Carbohydrate sulfotransferase 9,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,KEGG:hsa:83539`KO:K09673,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^100-333^E:1.6e-60,NA,NA,NA,NA,,
no,AD,DRA,DN13120_c0_g1_i2,DN13120_c0_g1,CHST9_HUMAN,Carbohydrate sulfotransferase 9,CHST9_HUMAN,Carbohydrate sulfotransferase 9,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0005576^cellular_component^extracellular region,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,KEGG:hsa:83539`KO:K09673,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^100-333^E:1.6e-60,NA,NA,NA,NA,,
no,AD,DRA,DN13149_c0_g1_i1,DN13149_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13149_c0_g1_i12,DN13149_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^115-165^E:5.5e-14,NA,NA,NA,NA,,
no,AD,DRA,DN13149_c0_g1_i26,DN13149_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^115-270^E:2.9e-47,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^118-264^E:2.5e-16,PF07993.12^NAD_binding_4^Male sterility protein^118-256^E:6.4e-06,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^122-274^E:8.7e-08",NA,,
no,AD,DRA,DN13149_c0_g1_i14,DN13149_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13149_c0_g1_i7,DN13149_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN37632_c0_g1_i9,DN37632_c0_g1,TSAL_GEOSL,L-threonine ammonia-lyase {ECO:0000303|PubMed:18245290},TSAL_GEOSL,L-threonine ammonia-lyase {ECO:0000303|PubMed:18245290},GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0009097^biological_process^isoleucine biosynthetic process,GO:0006565^biological_process^L-serine catabolic process,GO:0003941^molecular_function^L-serine ammonia-lyase activity,GO:0004794^molecular_function^L-threonine ammonia-lyase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0009097^biological_process^isoleucine biosynthetic process,GO:0006565^biological_process^L-serine catabolic process,KEGG:gsu:GSU0486`KO:K01754,COG1171^Threonine dehydratase,PF00291.25^PALP^Pyridoxal-phosphate dependent enzyme^127-416^E:2.4e-60,NA,NA,NA,NA,,
no,AD,DRA,DN11524_c0_g1_i2,DN11524_c0_g1,ECHD1_CHICK,Ethylmalonyl-CoA decarboxylase,ECHD1_CHICK,Ethylmalonyl-CoA decarboxylase,GO:0005829^cellular_component^cytosol,GO:0016831^molecular_function^carboxy-lyase activity,GO:0015451^molecular_function^decarboxylation-driven active transmembrane transporter activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0005829^cellular_component^cytosol,GO:0016831^molecular_function^carboxy-lyase activity,GO:0015451^molecular_function^decarboxylation-driven active transmembrane transporter activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^82-309^E:1.1e-34,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^86-288^E:4.8e-18,NA,NA,NA,,
no,AD,DRA,DN77656_c1_g1_i1,DN77656_c1_g1,YDJC_DANRE,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},.,NA,GO:0019213^molecular_function^deacetylase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,.,NA,NA,NA,NA,KEGG:dre:569036,COG3394^UPF0249 protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN10617_c0_g1_i2,DN10617_c0_g1,PYGB_HUMAN,"Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}",.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5834`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN10617_c0_g1_i5,DN10617_c0_g1,PYGB_HUMAN,"Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}",.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5834`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN10617_c0_g1_i3,DN10617_c0_g1,PYGB_MOUSE,"Glycogen phosphorylase, brain form",PYGB_RAT,"Glycogen phosphorylase, brain form",GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^1-117^E:4.6e-65,NA,NA,NA,NA,,
no,AD,DRA,DN10617_c0_g1_i4,DN10617_c0_g1,PYGB_PONAB,"Glycogen phosphorylase, brain form",PYGB_HUMAN,"Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}",GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0102499^molecular_function^SHG alpha-glucan phosphorylase activity,GO:0005977^biological_process^glycogen metabolic process,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,KEGG:hsa:5834`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^1-213^E:8.1e-102,NA,NA,NA,NA,,
no,AD,DRA,DN10617_c0_g1_i6,DN10617_c0_g1,PYGB_HUMAN,"Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}",.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5834`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN2840_c0_g1_i7,DN2840_c0_g1,PHS2_CHICK,Pterin-4-alpha-carbinolamine dehydratase 2,PHS2_CHICK,Pterin-4-alpha-carbinolamine dehydratase 2,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0006729^biological_process^tetrahydrobiopterin biosynthetic process,NA,NA,NA,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0006729^biological_process^tetrahydrobiopterin biosynthetic process,NA,NA,NA,KEGG:gga:374030`KO:K01724,.,PF01329.19^Pterin_4a^Pterin 4 alpha carbinolamine dehydratase^40-130^E:1.3e-31,NA,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i9,DN10772_c0_g1,CHSTF_RAT,Carbohydrate sulfotransferase 15,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0019319^biological_process^hexose biosynthetic process,.,NA,NA,NA,NA,KEGG:rno:286974`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,.,NA,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i3,DN10772_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,.,NA,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i13,DN10772_c0_g1,CHSTF_RAT,Carbohydrate sulfotransferase 15,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0019319^biological_process^hexose biosynthetic process,.,NA,NA,NA,NA,KEGG:rno:286974`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,.,NA,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i7,DN10772_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF13469.6^Sulfotransfer_3^Sulfotransferase family^253-497^E:6.4e-13,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^379-517^E:1.3e-12,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i10,DN10772_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF13469.6^Sulfotransfer_3^Sulfotransferase family^253-497^E:6.4e-13,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^379-517^E:1.3e-12,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i5,DN10772_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF13469.6^Sulfotransfer_3^Sulfotransferase family^253-497^E:6.4e-13,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^379-517^E:1.3e-12,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g1_i11,DN10772_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF13469.6^Sulfotransfer_3^Sulfotransferase family^253-497^E:6.4e-13,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^379-517^E:1.3e-12,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g2_i1,DN10772_c0_g2,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^43-89^E:3.7e-05,NA,NA,NA,NA,,
no,AD,DRA,DN10772_c0_g2_i4,DN10772_c0_g2,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^43-89^E:3.7e-05,NA,NA,NA,NA,,
no,AD,DRA,DN1983_c0_g1_i2,DN1983_c0_g1,XRCC5_MOUSE,X-ray repair cross-complementing protein 5,ECHD2_MOUSE,"Enoyl-CoA hydratase domain-containing protein 2, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0043564^cellular_component^Ku70:Ku80 complex,GO:0070419^cellular_component^nonhomologous end joining complex,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0005730^cellular_component^nucleolus,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,NA,KEGG:mmu:52430,COG1024^Enoyl-CoA hydratase,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^12-102^E:5.8e-15,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^13-103^E:1.1e-24,NA,NA,NA,,
no,AD,DRA,DN1983_c0_g1_i4,DN1983_c0_g1,XRCC5_MOUSE,X-ray repair cross-complementing protein 5,ECHD2_MOUSE,"Enoyl-CoA hydratase domain-containing protein 2, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0043564^cellular_component^Ku70:Ku80 complex,GO:0070419^cellular_component^nonhomologous end joining complex,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0005730^cellular_component^nucleolus,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,NA,KEGG:mmu:52430,COG1024^Enoyl-CoA hydratase,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^12-166^E:6.6e-28,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^13-181^E:3.3e-46,NA,NA,NA,,
no,AD,DRA,DN1983_c0_g1_i3,DN1983_c0_g1,ECHD2_HUMAN,"Enoyl-CoA hydratase domain-containing protein 2, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:55268,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN51469_c0_g1_i2,DN51469_c0_g1,PTPRG_HUMAN,Receptor-type tyrosine-protein phosphatase gamma,.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0042802^molecular_function^identical protein binding,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0005001^molecular_function^transmembrane receptor protein tyrosine phosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:5793`KO:K16667,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,.,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g1_i16,DN25109_c0_g1,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,.,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g1_i10,DN25109_c0_g1,SUCHY_HUMAN,Succinate--hydroxymethylglutarate CoA-transferase,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^1-103^E:8e-40,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g1_i12,DN25109_c0_g1,SUCHY_HUMAN,Succinate--hydroxymethylglutarate CoA-transferase,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^1-103^E:7.6e-40,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g1_i9,DN25109_c0_g1,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^7-92^E:3.5e-29,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g1_i17,DN25109_c0_g1,SUCHY_HUMAN,Succinate--hydroxymethylglutarate CoA-transferase,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^1-103^E:7.6e-40,NA,NA,NA,NA,,
no,AD,DRA,DN25109_c0_g4_i1,DN25109_c0_g4,SUCHY_MOUSE,Succinate--hydroxymethylglutarate CoA-transferase,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0047369^molecular_function^succinate-hydroxymethylglutarate CoA-transferase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:192136`KO:K18703,COG1804^l-carnitine dehydratase bile acid-inducible protein F,.,NA,NA,NA,NA,,
no,AD,DRA,DN33456_c0_g1_i3,DN33456_c0_g1,DHB4_HUMAN,Peroxisomal multifunctional enzyme type 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005782^cellular_component^peroxisomal matrix,GO:0005778^cellular_component^peroxisomal membrane,GO:0005777^cellular_component^peroxisome,.,NA,NA,NA,NA,KEGG:hsa:3295`KO:K12405,COG2030^maoc domain protein dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN33456_c0_g1_i1,DN33456_c0_g1,DHB4_HUMAN,Peroxisomal multifunctional enzyme type 2,DHB4_HUMAN,Peroxisomal multifunctional enzyme type 2,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005782^cellular_component^peroxisomal matrix,GO:0005778^cellular_component^peroxisomal membrane,GO:0005777^cellular_component^peroxisome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005782^cellular_component^peroxisomal matrix,GO:0005778^cellular_component^peroxisomal membrane,GO:0005777^cellular_component^peroxisome,KEGG:hsa:3295`KO:K12405,COG2030^maoc domain protein dehydratase,PF00106.25^adh_short^short chain dehydrogenase^43-228^E:6.4e-39,PF08659.10^KR^KR domain^43-200^E:3.1e-15,PF13561.6^adh_short_C2^Enoyl-(Acyl carrier protein) reductase^48-228^E:4.7e-33,PF13452.6^MaoC_dehydrat_N^N-terminal half of MaoC dehydratase^402-482^E:9.5e-08,PF01575.19^MaoC_dehydratas^MaoC like domain^514-630^E:7.7e-39,,
no,AD,DRA,DN33456_c0_g1_i2,DN33456_c0_g1,DHB4_HUMAN,Peroxisomal multifunctional enzyme type 2,DHB4_HUMAN,Peroxisomal multifunctional enzyme type 2,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005782^cellular_component^peroxisomal matrix,GO:0005778^cellular_component^peroxisomal membrane,GO:0005777^cellular_component^peroxisome,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005782^cellular_component^peroxisomal matrix,GO:0005778^cellular_component^peroxisomal membrane,GO:0005777^cellular_component^peroxisome,KEGG:hsa:3295`KO:K12405,COG2030^maoc domain protein dehydratase,PF00106.25^adh_short^short chain dehydrogenase^43-228^E:4.9e-39,PF08659.10^KR^KR domain^43-200^E:2.4e-15,PF13561.6^adh_short_C2^Enoyl-(Acyl carrier protein) reductase^48-228^E:4.3e-33,PF13452.6^MaoC_dehydrat_N^N-terminal half of MaoC dehydratase^402-482^E:7.6e-08,PF01575.19^MaoC_dehydratas^MaoC like domain^514-630^E:6.1e-39,,
no,AD,DRA,DN6823_c0_g1_i2,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^2-298^E:5.4e-100,PF00694.19^Aconitase_C^Aconitase C-terminal domain^427-552^E:2.7e-45,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i1,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^2-298^E:4.5e-100,PF00694.19^Aconitase_C^Aconitase C-terminal domain^427-524^E:1.2e-28,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i3,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^62-564^E:6.8e-181,PF00694.19^Aconitase_C^Aconitase C-terminal domain^693-818^E:5.2e-45,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i7,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^2-115^E:5.3e-40,PF00694.19^Aconitase_C^Aconitase C-terminal domain^244-341^E:6e-29,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i6,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-335^E:2.1e-115,PF00694.19^Aconitase_C^Aconitase C-terminal domain^464-589^E:3.3e-45,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i5,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-152^E:6.6e-35,NA,NA,NA,NA,,
no,AD,DRA,DN6823_c0_g1_i8,DN6823_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,ACOC_CHICK,Cytoplasmic aconitate hydratase,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-398^E:9.4e-148,PF00694.19^Aconitase_C^Aconitase C-terminal domain^527-652^E:3.8e-45,NA,NA,NA,,
no,AD,DRA,DN24388_c1_g1_i7,DN24388_c1_g1,ACON_MOUSE,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0043209^cellular_component^myelin sheath,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:mmu:11429`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN15337_c0_g1_i3,DN15337_c0_g1,HACD2_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,.,NA,NA,NA,NA,KEGG:hsa:201562`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN15382_c0_g1_i2,DN15382_c0_g1,UXS1_DANRE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,GO:0048040^molecular_function^UDP-glucuronate decarboxylase activity,.,NA,NA,NA,NA,KEGG:dre:192315`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN32666_c0_g1_i1,DN32666_c0_g1,ENOA_RAT,Alpha-enolase,.,NA,GO:0099738^cellular_component^cell cortex region,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030426^cellular_component^growth cone,.,NA,NA,NA,NA,KEGG:rno:24333`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i14,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^164-410^E:5e-12",NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i1,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i2,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^269-472^E:1.4e-24",NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i4,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^3-161^E:1.1e-10",NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i6,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN39968_c0_g1_i15,DN39968_c0_g1,ENO4_HUMAN,Enolase 4 {ECO:0000305},ENO4_HUMAN,Enolase 4 {ECO:0000305},GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006096^biological_process^glycolytic process,NA,KEGG:hsa:387712`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^97-343^E:3.1e-12",NA,NA,NA,NA,,
no,AD,DRA,DN39928_c0_g1_i1,DN39928_c0_g1,PYGB_RAT,"Glycogen phosphorylase, brain form",.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,.,NA,NA,NA,NA,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN14518_c0_g1_i2,DN14518_c0_g1,FUMH_DANRE,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:dre:393938`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN14518_c0_g1_i1,DN14518_c0_g1,FUMH_DANRE,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:dre:393938`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN56150_c0_g1_i1,DN56150_c0_g1,CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172009`KO:K18588,COG2867^Cyclase dehydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN31810_c0_g1_i4,DN31810_c0_g1,PYGL_MOUSE,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,.,NA,NA,NA,NA,KEGG:mmu:110095`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN9939_c0_g1_i3,DN9939_c0_g1,DRAXI_CHICK,Draxin {ECO:0000255|HAMAP-Rule:MF_03060},.,NA,GO:0005576^cellular_component^extracellular region,GO:0007411^biological_process^axon guidance,GO:0021528^biological_process^commissural neuron differentiation in spinal cord,GO:0021516^biological_process^dorsal spinal cord development,GO:0030900^biological_process^forebrain development,.,NA,NA,NA,NA,KEGG:gga:419492,ENOG4111MNU^dorsal inhibitory axon guidance protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN9939_c0_g1_i1,DN9939_c0_g1,DRAXI_CHICK,Draxin {ECO:0000255|HAMAP-Rule:MF_03060},.,NA,GO:0005576^cellular_component^extracellular region,GO:0007411^biological_process^axon guidance,GO:0021528^biological_process^commissural neuron differentiation in spinal cord,GO:0021516^biological_process^dorsal spinal cord development,GO:0030900^biological_process^forebrain development,.,NA,NA,NA,NA,KEGG:gga:419492,ENOG4111MNU^dorsal inhibitory axon guidance protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN9939_c0_g1_i9,DN9939_c0_g1,DRAXI_CHICK,Draxin {ECO:0000255|HAMAP-Rule:MF_03060},.,NA,GO:0005576^cellular_component^extracellular region,GO:0007411^biological_process^axon guidance,GO:0021528^biological_process^commissural neuron differentiation in spinal cord,GO:0021516^biological_process^dorsal spinal cord development,GO:0030900^biological_process^forebrain development,.,NA,NA,NA,NA,KEGG:gga:419492,ENOG4111MNU^dorsal inhibitory axon guidance protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN9939_c0_g1_i8,DN9939_c0_g1,DRAXI_CHICK,Draxin {ECO:0000255|HAMAP-Rule:MF_03060},.,NA,GO:0005576^cellular_component^extracellular region,GO:0007411^biological_process^axon guidance,GO:0021528^biological_process^commissural neuron differentiation in spinal cord,GO:0021516^biological_process^dorsal spinal cord development,GO:0030900^biological_process^forebrain development,.,NA,NA,NA,NA,KEGG:gga:419492,ENOG4111MNU^dorsal inhibitory axon guidance protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN3211_c0_g2_i1,DN3211_c0_g2,CAH9_MOUSE,Carbonic anhydrase 9,CAH9_MOUSE,Carbonic anhydrase 9,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031528^cellular_component^microvillus membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031528^cellular_component^microvillus membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,KEGG:mmu:230099`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^89-338^E:2e-93,NA,NA,NA,NA,,
no,AD,DRA,DN29061_c0_g2_i1,DN29061_c0_g2,NIT2_BOVIN,Omega-amidase NIT2,NIT2_BOVIN,Omega-amidase NIT2,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN29061_c0_g3_i2,DN29061_c0_g3,NIT2_BOVIN,Omega-amidase NIT2,NIT2_BOVIN,Omega-amidase NIT2,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^12-263^E:2.5e-65,NA,NA,NA,NA,,
no,AD,DRA,DN29061_c0_g3_i1,DN29061_c0_g3,NIT2_BOVIN,Omega-amidase NIT2,NIT2_BOVIN,Omega-amidase NIT2,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^2-151^E:1.8e-39,NA,NA,NA,NA,,
no,AD,DRA,DN29061_c0_g3_i5,DN29061_c0_g3,NIT2_BOVIN,Omega-amidase NIT2,NIT2_BOVIN,Omega-amidase NIT2,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^7-123^E:1.1e-28,NA,NA,NA,NA,,
no,AD,DRA,DN29061_c0_g3_i3,DN29061_c0_g3,NIT2_BOVIN,Omega-amidase NIT2,NIT2_BOVIN,Omega-amidase NIT2,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,GO:0005737^cellular_component^cytoplasm,GO:0050152^molecular_function^omega-amidase activity,GO:0006528^biological_process^asparagine metabolic process,GO:0006541^biological_process^glutamine metabolic process,GO:0006107^biological_process^oxaloacetate metabolic process,KEGG:bta:520620`KO:K13566,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^12-235^E:3.8e-56,NA,NA,NA,NA,,
no,AD,DRA,DN12931_c0_g1_i1,DN12931_c0_g1,CHST1_HUMAN,Carbohydrate sulfotransferase 1,CHST1_HUMAN,Carbohydrate sulfotransferase 1,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0045130^molecular_function^keratan sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0045130^molecular_function^keratan sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,KEGG:hsa:8534`KO:K01022,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^68-392^E:1.5e-58,PF13469.6^Sulfotransfer_3^Sulfotransferase family^235-333^E:1.1e-10,NA,NA,NA,,
no,AD,DRA,DN12931_c0_g1_i2,DN12931_c0_g1,CHST1_HUMAN,Carbohydrate sulfotransferase 1,CHST1_HUMAN,Carbohydrate sulfotransferase 1,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0045130^molecular_function^keratan sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0045130^molecular_function^keratan sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,KEGG:hsa:8534`KO:K01022,ENOG4110V0B^carbohydrate (N-acetylglucosamine 6-O) sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^68-392^E:1.5e-58,PF13469.6^Sulfotransfer_3^Sulfotransferase family^235-333^E:1.1e-10,NA,NA,NA,,
no,AD,DRA,DN62748_c0_g1_i1,DN62748_c0_g1,ECHD3_HUMAN,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000305}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003824^molecular_function^catalytic activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:79746,ENOG410XPEY^Enoyl-CoA hydratase/isomerase family,.,NA,NA,NA,NA,,
no,AD,DRA,DN62875_c0_g1_i3,DN62875_c0_g1,HEM2_HUMAN,Delta-aminolevulinic acid dehydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:210`KO:K01698,COG0113^delta-aminolevulinic acid dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN7299_c3_g1_i2,DN7299_c3_g1,GMDS_CRIGR,"GDP-mannose 4,6 dehydratase",GMDS_MOUSE,"GDP-mannose 4,6 dehydratase","GO:0008446^molecular_function^GDP-mannose 4,6-dehydratase activity",GO:0042802^molecular_function^identical protein binding,GO:0070401^molecular_function^NADP+ binding,GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,GO:0019673^biological_process^GDP-mannose metabolic process,GO:0005737^cellular_component^cytoplasm,"GO:0008446^molecular_function^GDP-mannose 4,6-dehydratase activity",GO:0042802^molecular_function^identical protein binding,GO:0070401^molecular_function^NADP+ binding,GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,KEGG:mmu:218138`KO:K01711,"COG1089^GDP-mannose 4,6-dehydratase",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^71-319^E:1.1e-73,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^72-403^E:7.4e-164",PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^72-249^E:8.1e-07,NA,NA,,
no,AD,DRA,DN44761_c0_g2_i1,DN44761_c0_g2,CAH2_CHICK,Carbonic anhydrase 2,CAH2_CHICK,Carbonic anhydrase 2,GO:0045177^cellular_component^apical part of cell,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043209^cellular_component^myelin sheath,GO:0045177^cellular_component^apical part of cell,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043209^cellular_component^myelin sheath,KEGG:gga:396257`KO:K18245,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^4-258^E:1e-95,NA,NA,NA,NA,,
no,AD,DRA,DN44761_c0_g2_i2,DN44761_c0_g2,CAH2_CHICK,Carbonic anhydrase 2,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043209^cellular_component^myelin sheath,.,NA,NA,NA,NA,KEGG:gga:396257`KO:K18245,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN35740_c0_g1_i1,DN35740_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN35740_c0_g1_i7,DN35740_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN51010_c0_g2_i2,DN51010_c0_g2,FUMH_PIG,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:ssc:100627128`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN51010_c0_g2_i3,DN51010_c0_g2,FUMH_PIG,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:ssc:100627128`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN51010_c0_g2_i1,DN51010_c0_g2,FUMH_PIG,"Fumarate hydratase, mitochondrial {ECO:0000250|UniProtKB:P07954}",.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0045239^cellular_component^tricarboxylic acid cycle enzyme complex,.,NA,NA,NA,NA,KEGG:ssc:100627128`KO:K01679,COG0114^fumarate hydratase class II,.,NA,NA,NA,NA,,
no,AD,DRA,DN3566_c0_g1_i4,DN3566_c0_g1,CHSTE_HUMAN,Carbohydrate sulfotransferase 14,CHSTE_HUMAN,Carbohydrate sulfotransferase 14,GO:0070062^cellular_component^extracellular exosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0042301^molecular_function^phosphate ion binding,GO:0070062^cellular_component^extracellular exosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0042301^molecular_function^phosphate ion binding,KEGG:hsa:113189`KO:K08105,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^180-404^E:3.8e-52,NA,NA,NA,NA,,
yes,AD,DRA,DN3507_c0_g1_i7,DN3507_c0_g1,DRA_HUMAN,"HLA class II histocompatibility antigen, DR alpha chain",.,NA,GO:0009986^cellular_component^cell surface,GO:0030669^cellular_component^clathrin-coated endocytic vesicle membrane,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0012507^cellular_component^ER to Golgi transport vesicle membrane,GO:0070062^cellular_component^extracellular exosome,.,NA,NA,NA,NA,KEGG:hsa:3122`KO:K06752,ENOG410YHX9^Major histocompatibility complex class II,.,NA,NA,NA,NA,,
yes,AD,DRA,DN3507_c0_g1_i10,DN3507_c0_g1,HA22_MOUSE,"H-2 class II histocompatibility antigen, E-K alpha chain",DRA_HUMAN,"HLA class II histocompatibility antigen, DR alpha chain",GO:0016021^cellular_component^integral component of membrane,GO:0042613^cellular_component^MHC class II protein complex,GO:0002250^biological_process^adaptive immune response,GO:0002504^biological_process^antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,NA,GO:0009986^cellular_component^cell surface,GO:0030669^cellular_component^clathrin-coated endocytic vesicle membrane,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0012507^cellular_component^ER to Golgi transport vesicle membrane,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:3122`KO:K06752,ENOG410YHX9^Major histocompatibility complex class II,"PF00993.20^MHC_II_alpha^Class II histocompatibility antigen, alpha domain^27-108^E:1.8e-33",NA,NA,NA,NA,,
yes,AD,DRA,DN3507_c0_g1_i3,DN3507_c0_g1,DQA2_HUMAN,"HLA class II histocompatibility antigen, DQ alpha 2 chain",DRA_HUMAN,"HLA class II histocompatibility antigen, DR alpha chain",GO:0030669^cellular_component^clathrin-coated endocytic vesicle membrane,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0010008^cellular_component^endosome membrane,GO:0012507^cellular_component^ER to Golgi transport vesicle membrane,GO:0000139^cellular_component^Golgi membrane,GO:0009986^cellular_component^cell surface,GO:0030669^cellular_component^clathrin-coated endocytic vesicle membrane,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0012507^cellular_component^ER to Golgi transport vesicle membrane,GO:0070062^cellular_component^extracellular exosome,KEGG:hsa:3122`KO:K06752,ENOG410YHX9^Major histocompatibility complex class II,"PF00993.20^MHC_II_alpha^Class II histocompatibility antigen, alpha domain^27-108^E:1.8e-33",NA,NA,NA,NA,,
yes,AD,DRA,DN3507_c0_g1_i8,DN3507_c0_g1,DRA_HUMAN,"HLA class II histocompatibility antigen, DR alpha chain",DRA_MACMU,"Mamu class II histocompatibility antigen, DR alpha chain",GO:0009986^cellular_component^cell surface,GO:0030669^cellular_component^clathrin-coated endocytic vesicle membrane,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0012507^cellular_component^ER to Golgi transport vesicle membrane,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0042613^cellular_component^MHC class II protein complex,GO:0002250^biological_process^adaptive immune response,GO:0002504^biological_process^antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,NA,KEGG:hsa:3122`KO:K06752,ENOG410YHX9^Major histocompatibility complex class II,"PF00993.20^MHC_II_alpha^Class II histocompatibility antigen, alpha domain^27-108^E:5.1e-33",PF07654.15^C1-set^Immunoglobulin C1-set domain^115-196^E:8.9e-25,NA,NA,NA,,
no,AD,DRA,DN84783_c0_g1_i2,DN84783_c0_g1,PYGB_RAT,"Glycogen phosphorylase, brain form",.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,.,NA,NA,NA,NA,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN2600_c0_g1_i1,DN2600_c0_g1,ENOA_ANAPL,Alpha-enolase,ENOA_CHICK,Alpha-enolase,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0005212^molecular_function^structural constituent of eye lens,GO:0006096^biological_process^glycolytic process,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:396017`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^2-54^E:4.6e-21","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^63-143^E:8.7e-43",NA,NA,NA,,
no,AD,DRA,DN2600_c0_g1_i5,DN2600_c0_g1,ENOA_CHICK,Alpha-enolase,ENOA_CHICK,Alpha-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:396017`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^1-30^E:2.5e-09","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^39-326^E:1.2e-159",PF13378.6^MR_MLE_C^Enolase C-terminal domain-like^168-267^E:4.9e-09,NA,NA,,
no,AD,DRA,DN2600_c0_g1_i6,DN2600_c0_g1,ENOA_CHICK,Alpha-enolase,ENOA_ANAPL,Alpha-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0005212^molecular_function^structural constituent of eye lens,GO:0006096^biological_process^glycolytic process,KEGG:apla:101793724`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^1-113^E:2.1e-53",NA,NA,NA,NA,,
no,AD,DRA,DN33046_c0_g1_i2,DN33046_c0_g1,.,NA,3BHS7_RAT,3 beta-hydroxysteroid dehydrogenase type 7,.,NA,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",KEGG:rno:246211`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^71-108^E:2.2e-08,NA,NA,NA,NA,,
no,AD,DRA,DN50272_c0_g1_i1,DN50272_c0_g1,HACD3_CHICK,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000305},.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:gga:415539`KO:K10703,COG5198^Protein tyrosine phosphatase-like,.,NA,NA,NA,NA,,
no,AD,DRA,DN1719_c0_g1_i7,DN1719_c0_g1,CAH8_HUMAN,Carbonic anhydrase-related protein,CAH8_HUMAN,Carbonic anhydrase-related protein,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,KEGG:hsa:767`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^22-203^E:1e-52,NA,NA,NA,NA,,
no,AD,DRA,DN1719_c0_g1_i1,DN1719_c0_g1,CAH8_HUMAN,Carbonic anhydrase-related protein,CAH8_HUMAN,Carbonic anhydrase-related protein,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,KEGG:hsa:767`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^22-187^E:7.3e-48,NA,NA,NA,NA,,
no,AD,DRA,DN1719_c0_g1_i3,DN1719_c0_g1,CAH8_HUMAN,Carbonic anhydrase-related protein,CAH8_HUMAN,Carbonic anhydrase-related protein,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,KEGG:hsa:767`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^22-281^E:2.2e-80,NA,NA,NA,NA,,
no,AD,DRA,DN1719_c0_g1_i4,DN1719_c0_g1,CAH8_MOUSE,Carbonic anhydrase-related protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,.,NA,NA,NA,NA,KEGG:mmu:12319`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1719_c0_g1_i5,DN1719_c0_g1,CAH8_HUMAN,Carbonic anhydrase-related protein,CAH8_HUMAN,Carbonic anhydrase-related protein,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0048015^biological_process^phosphatidylinositol-mediated signaling,NA,KEGG:hsa:767`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^22-203^E:1e-52,NA,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i5,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^103-165^E:2.6e-13,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^245-330^E:6.4e-23,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i3,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-345^E:8.2e-106,PF00694.19^Aconitase_C^Aconitase C-terminal domain^474-534^E:1.6e-08,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i8,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^8-168^E:1.3e-46,NA,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i19,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^2-252^E:6e-85,NA,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i7,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-345^E:1.4e-105,PF00694.19^Aconitase_C^Aconitase C-terminal domain^474-600^E:9.6e-41,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i20,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-119^E:1.9e-34,PF00694.19^Aconitase_C^Aconitase C-terminal domain^248-308^E:7e-09,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i12,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-119^E:3.7e-34,PF00694.19^Aconitase_C^Aconitase C-terminal domain^248-374^E:4.7e-41,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i16,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,.,NA,NA,NA,NA,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i18,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^7-102^E:9.9e-23,NA,NA,NA,NA,,
no,AD,DRA,DN1753_c0_g1_i14,DN1753_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,IREB2_CHICK,Iron-responsive element-binding protein 2,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,PF00330.20^Aconitase^Aconitase family (aconitate hydratase)^1-119^E:3.7e-34,PF00694.19^Aconitase_C^Aconitase C-terminal domain^248-374^E:4.7e-41,NA,NA,NA,,
no,AD,DRA,DN7538_c0_g1_i3,DN7538_c0_g1,HACD2_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 {ECO:0000305},HACD2_HUMAN,Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0102343^molecular_function^3-hydroxy-arachidoyl-CoA dehydratase activity,GO:0102344^molecular_function^3-hydroxy-behenoyl-CoA dehydratase activity,KEGG:hsa:201562`KO:K10703,COG5198^Protein tyrosine phosphatase-like,"PF04387.14^PTPLA^Protein tyrosine phosphatase-like protein, PTPLA^103-263^E:4e-60",NA,NA,NA,NA,,
no,AD,DRA,DN82072_c0_g1_i1,DN82072_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN82072_c1_g1_i1,DN82072_c1_g1,ACOC_HUMAN,Cytoplasmic aconitate hydratase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:48`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN82072_c1_g1_i2,DN82072_c1_g1,ACOC_HUMAN,Cytoplasmic aconitate hydratase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:hsa:48`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN47733_c0_g1_i1,DN47733_c0_g1,PHS2_HUMAN,Pterin-4-alpha-carbinolamine dehydratase 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0004505^molecular_function^phenylalanine 4-monooxygenase activity,"GO:0045893^biological_process^positive regulation of transcription, DNA-templated",GO:0051291^biological_process^protein heterooligomerization,.,NA,NA,NA,NA,KEGG:hsa:84105`KO:K01724,COG2154^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN97582_c0_g1_i1,DN97582_c0_g1,PYGL_HUMAN,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,.,NA,NA,NA,NA,KEGG:hsa:5836`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN197_c1_g1_i8,DN197_c1_g1,CAH7_HUMAN,Carbonic anhydrase 7,CAH7_MOUSE,Carbonic anhydrase 7,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0032849^biological_process^positive regulation of cellular pH reduction,"GO:0032230^biological_process^positive regulation of synaptic transmission, GABAergic",KEGG:mmu:12354`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^58-94^E:3.5e-09,NA,NA,NA,NA,,
no,AD,DRA,DN197_c1_g1_i3,DN197_c1_g1,CAH7_HUMAN,Carbonic anhydrase 7,CAH7_HUMAN,Carbonic anhydrase 7,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,KEGG:hsa:766`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^25-280^E:1.8e-99,NA,NA,NA,NA,,
no,AD,DRA,DN197_c1_g1_i1,DN197_c1_g1,CAH7_HUMAN,Carbonic anhydrase 7,CAH7_MOUSE,Carbonic anhydrase 7,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0032849^biological_process^positive regulation of cellular pH reduction,"GO:0032230^biological_process^positive regulation of synaptic transmission, GABAergic",KEGG:mmu:12354`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^58-94^E:3.5e-09,NA,NA,NA,NA,,
no,AD,DRA,DN197_c1_g1_i6,DN197_c1_g1,CAH7_HUMAN,Carbonic anhydrase 7,CAH7_HUMAN,Carbonic anhydrase 7,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,KEGG:hsa:766`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^31-214^E:4.6e-74,NA,NA,NA,NA,,
no,AD,DRA,DN197_c1_g1_i7,DN197_c1_g1,CAH7_HUMAN,Carbonic anhydrase 7,CAH7_HUMAN,Carbonic anhydrase 7,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,KEGG:hsa:766`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^25-141^E:7.6e-41,NA,NA,NA,NA,,
no,AD,DRA,DN4899_c0_g1_i7,DN4899_c0_g1,ECI2_HUMAN,"Enoyl-CoA delta isomerase 2, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:10455`KO:K13239,COG1024^Enoyl-CoA hydratase`COG4281^Acyl-CoA binding domain containing,.,NA,NA,NA,NA,,
no,AD,DRA,DN4899_c0_g1_i10,DN4899_c0_g1,ECI2_HUMAN,"Enoyl-CoA delta isomerase 2, mitochondrial",ECI2_HUMAN,"Enoyl-CoA delta isomerase 2, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:10455`KO:K13239,COG1024^Enoyl-CoA hydratase`COG4281^Acyl-CoA binding domain containing,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^15-176^E:1.7e-26,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^21-173^E:3.4e-08,NA,NA,NA,,
no,AD,DRA,DN4899_c0_g1_i5,DN4899_c0_g1,ECI2_HUMAN,"Enoyl-CoA delta isomerase 2, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:10455`KO:K13239,COG1024^Enoyl-CoA hydratase`COG4281^Acyl-CoA binding domain containing,.,NA,NA,NA,NA,,
no,AD,DRA,DN4899_c0_g1_i8,DN4899_c0_g1,ECI2_HUMAN,"Enoyl-CoA delta isomerase 2, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:10455`KO:K13239,COG1024^Enoyl-CoA hydratase`COG4281^Acyl-CoA binding domain containing,.,NA,NA,NA,NA,,
no,AD,DRA,DN21557_c1_g1_i1,DN21557_c1_g1,ACON_RAT,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:rno:79250`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN21557_c1_g1_i2,DN21557_c1_g1,ACON_RAT,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:rno:79250`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN21557_c2_g1_i1,DN21557_c2_g1,ACON_BOVIN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN21641_c0_g1_i2,DN21641_c0_g1,GNTK_MOUSE,Probable gluconokinase,GNTK_MOUSE,Probable gluconokinase,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,KEGG:mmu:75731`KO:K00851,"COG3265^carbohydrate kinase, thermoresistant glucokinase family",PF01202.22^SKI^Shikimate kinase^47-102^E:4.3e-10,NA,NA,NA,NA,,
no,AD,DRA,DN21641_c0_g1_i3,DN21641_c0_g1,GNTK_HUMAN,Probable gluconokinase,GNTK_HUMAN,Probable gluconokinase,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,KEGG:hsa:414328`KO:K00851,"COG3265^carbohydrate kinase, thermoresistant glucokinase family",.,NA,NA,NA,NA,,
no,AD,DRA,DN21641_c0_g1_i1,DN21641_c0_g1,GNTK_HUMAN,Probable gluconokinase,GNTK_HUMAN,Probable gluconokinase,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,GO:0005524^molecular_function^ATP binding,GO:0046316^molecular_function^gluconokinase activity,GO:0046177^biological_process^D-gluconate catabolic process,NA,NA,KEGG:hsa:414328`KO:K00851,"COG3265^carbohydrate kinase, thermoresistant glucokinase family",PF13671.6^AAA_33^AAA domain^40-190^E:1.5e-09,PF13238.6^AAA_18^AAA domain^41-171^E:1.7e-07,PF01202.22^SKI^Shikimate kinase^47-172^E:1.8e-13,NA,NA,,
no,AD,DRA,DN12593_c1_g1_i3,DN12593_c1_g1,CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,KEGG:pon:100172009`KO:K18588,COG2867^Cyclase dehydrase,PF03364.20^Polyketide_cyc^Polyketide cyclase / dehydrase and lipid transport^74-203^E:1.6e-22,NA,NA,NA,NA,,
no,AD,DRA,DN12593_c1_g1_i2,DN12593_c1_g1,CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,KEGG:pon:100172009`KO:K18588,COG2867^Cyclase dehydrase,PF03364.20^Polyketide_cyc^Polyketide cyclase / dehydrase and lipid transport^65-194^E:1.5e-22,NA,NA,NA,NA,,
no,AD,DRA,DN20801_c0_g1_i8,DN20801_c0_g1,ACON_PIG,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ssc:396999`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN20801_c0_g1_i11,DN20801_c0_g1,ACON_BOVIN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN20801_c0_g1_i12,DN20801_c0_g1,ACON_PIG,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ssc:396999`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN11724_c0_g1_i9,DN11724_c0_g1,TDH_BOVIN,"L-threonine 3-dehydrogenase, mitochondrial {ECO:0000305}",TDH_BOVIN,"L-threonine 3-dehydrogenase, mitochondrial {ECO:0000305}",GO:0005739^cellular_component^mitochondrion,GO:0050662^molecular_function^coenzyme binding,GO:0042802^molecular_function^identical protein binding,GO:0008743^molecular_function^L-threonine 3-dehydrogenase activity,GO:0019518^biological_process^L-threonine catabolic process to glycine,GO:0005739^cellular_component^mitochondrion,GO:0050662^molecular_function^coenzyme binding,GO:0042802^molecular_function^identical protein binding,GO:0008743^molecular_function^L-threonine 3-dehydrogenase activity,GO:0019518^biological_process^L-threonine catabolic process to glycine,KEGG:bta:511957`KO:K15789,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^57-203^E:5.1e-07,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^58-293^E:1.5e-21,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^59-359^E:2.2e-15",PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^59-179^E:9e-07,PF07993.12^NAD_binding_4^Male sterility protein^119-274^E:7.8e-06,,
no,AD,DRA,DN11724_c0_g1_i5,DN11724_c0_g1,TDH_BOVIN,"L-threonine 3-dehydrogenase, mitochondrial {ECO:0000305}",TDH_BOVIN,"L-threonine 3-dehydrogenase, mitochondrial {ECO:0000305}",GO:0005739^cellular_component^mitochondrion,GO:0050662^molecular_function^coenzyme binding,GO:0042802^molecular_function^identical protein binding,GO:0008743^molecular_function^L-threonine 3-dehydrogenase activity,GO:0019518^biological_process^L-threonine catabolic process to glycine,GO:0005739^cellular_component^mitochondrion,GO:0050662^molecular_function^coenzyme binding,GO:0042802^molecular_function^identical protein binding,GO:0008743^molecular_function^L-threonine 3-dehydrogenase activity,GO:0019518^biological_process^L-threonine catabolic process to glycine,KEGG:bta:511957`KO:K15789,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^57-203^E:4e-07,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^58-293^E:1.1e-21,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^59-219^E:7.9e-13",PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^59-179^E:7.2e-07,PF07993.12^NAD_binding_4^Male sterility protein^119-274^E:5.9e-06,,
no,AD,DRA,DN3019_c0_g1_i5,DN3019_c0_g1,HIBCH_CHICK,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",HIBCH_CHICK,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0003860^molecular_function^3-hydroxyisobutyryl-CoA hydrolase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0006574^biological_process^valine catabolic process,NA,GO:0005739^cellular_component^mitochondrion,GO:0003860^molecular_function^3-hydroxyisobutyryl-CoA hydrolase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0006574^biological_process^valine catabolic process,NA,KEGG:gga:423979`KO:K05605,COG1024^Enoyl-CoA hydratase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^41-285^E:2.7e-33,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^46-375^E:5.7e-141,NA,NA,NA,,
no,AD,DRA,DN27099_c0_g1_i1,DN27099_c0_g1,VNN1_PIG,Pantetheinase,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,.,NA,NA,NA,NA,KEGG:ssc:397246`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27097_c0_g1_i1,DN27097_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27097_c0_g2_i1,DN27097_c0_g2,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27033_c0_g1_i1,DN27033_c0_g1,ACON_PIG,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ssc:396999`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27033_c0_g1_i5,DN27033_c0_g1,ACON_PIG,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:ssc:396999`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27033_c1_g1_i2,DN27033_c1_g1,ACON_BOVIN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27033_c2_g1_i2,DN27033_c2_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN27044_c0_g1_i3,DN27044_c0_g1,FCL_DROME,Probable GDP-L-fucose synthase,.,NA,GO:0050662^molecular_function^coenzyme binding,GO:0050577^molecular_function^GDP-L-fucose synthase activity,"GO:0047918^molecular_function^GDP-mannose 3,5-epimerase activity",GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,GO:0033227^biological_process^dsRNA transport,.,NA,NA,NA,NA,KEGG:dme:Dmel_CG3495`KO:K02377,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN86960_c0_g1_i1,DN86960_c0_g1,PYGL_HUMAN,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,.,NA,NA,NA,NA,KEGG:hsa:5836`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN513_c0_g1_i8,DN513_c0_g1,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:67171`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^9-232^E:1.2e-47,NA,NA,NA,NA,,
no,AD,DRA,DN513_c0_g1_i3,DN513_c0_g1,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:67171`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^9-232^E:1.2e-47,NA,NA,NA,NA,,
no,AD,DRA,DN513_c0_g1_i10,DN513_c0_g1,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:67171`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^9-232^E:1.2e-47,NA,NA,NA,NA,,
no,AD,DRA,DN513_c0_g1_i5,DN513_c0_g1,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:67171`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^9-232^E:1.2e-47,NA,NA,NA,NA,,
no,AD,DRA,DN513_c0_g1_i11,DN513_c0_g1,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,DRAM2_MOUSE,DNA damage-regulated autophagy modulator protein 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:mmu:67171`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^9-232^E:1.2e-47,NA,NA,NA,NA,,
no,AD,DRA,DN1292_c6_g1_i1,DN1292_c6_g1,PTPRG_CHICK,Receptor-type tyrosine-protein phosphatase gamma,PTPRG_CHICK,Receptor-type tyrosine-protein phosphatase gamma,GO:0016021^cellular_component^integral component of membrane,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0006470^biological_process^protein dephosphorylation,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0006470^biological_process^protein dephosphorylation,NA,NA,.,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^60-319^E:9.9e-80,PF00041.21^fn3^Fibronectin type III domain^349-429^E:1.1e-09,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^851-1095^E:2.7e-88,PF00102.27^Y_phosphatase^Protein-tyrosine phosphatase^1152-1385^E:2.8e-58,NA,,
no,AD,DRA,DN94190_c0_g1_i1,DN94190_c0_g1,PYGB_PONAB,"Glycogen phosphorylase, brain form",.,NA,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0102499^molecular_function^SHG alpha-glucan phosphorylase activity,GO:0005977^biological_process^glycogen metabolic process,.,NA,NA,NA,NA,KEGG:pon:100173733`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN25432_c0_g1_i1,DN25432_c0_g1,CHST8_HUMAN,Carbohydrate sulfotransferase 8,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:64377`KO:K09672,ENOG4111GJR^carbohydrate,.,NA,NA,NA,NA,,
no,AD,DRA,DN7037_c0_g1_i8,DN7037_c0_g1,CAH5B_HUMAN,"Carbonic anhydrase 5B, mitochondrial",CAH5B_HUMAN,"Carbonic anhydrase 5B, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,KEGG:hsa:11238`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^70-314^E:7.2e-86,NA,NA,NA,NA,,
no,AD,DRA,DN7037_c0_g1_i4,DN7037_c0_g1,CAH5B_HUMAN,"Carbonic anhydrase 5B, mitochondrial",CAH5B_HUMAN,"Carbonic anhydrase 5B, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,KEGG:hsa:11238`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^44-288^E:5e-86,NA,NA,NA,NA,,
no,AD,DRA,DN992_c0_g1_i13,DN992_c0_g1,NIT1_RAT,Deaminated glutathione amidase,NIT1_RAT,Deaminated glutathione amidase,GO:0005739^cellular_component^mitochondrion,"GO:0016811^molecular_function^hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides",GO:0006807^biological_process^nitrogen compound metabolic process,NA,NA,GO:0005739^cellular_component^mitochondrion,"GO:0016811^molecular_function^hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides",GO:0006807^biological_process^nitrogen compound metabolic process,NA,NA,KEGG:rno:289222`KO:K11206,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^36-294^E:2.1e-66,NA,NA,NA,NA,,
no,AD,DRA,DN929_c0_g1_i8,DN929_c0_g1,VNN1_BOVIN,Pantetheinase,VNN2_HUMAN,Vascular non-inflammatory molecule 2,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,KEGG:hsa:8875`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^111-343^E:5.5e-21,NA,NA,NA,NA,,
no,AD,DRA,DN929_c0_g1_i10,DN929_c0_g1,VNN2_HUMAN,Vascular non-inflammatory molecule 2,VNN2_HUMAN,Vascular non-inflammatory molecule 2,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,KEGG:hsa:8875`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN929_c0_g1_i6,DN929_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN929_c0_g1_i4,DN929_c0_g1,VNN1_BOVIN,Pantetheinase,VNN1_BOVIN,Pantetheinase,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^111-362^E:8e-25,NA,NA,NA,NA,,
no,AD,DRA,DN16438_c0_g1_i2,DN16438_c0_g1,CAH13_MOUSE,Carbonic anhydrase 13,CAH13_MOUSE,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:71934`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^16-159^E:4e-47,NA,NA,NA,NA,,
no,AD,DRA,DN16438_c0_g1_i6,DN16438_c0_g1,CAH13_MOUSE,Carbonic anhydrase 13,CAH13_MOUSE,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:mmu:71934`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^1-166^E:5.3e-62,NA,NA,NA,NA,,
no,AD,DRA,DN6101_c0_g1_i5,DN6101_c0_g1,ECHA_HUMAN,"Trifunctional enzyme subunit alpha, mitochondrial",ECHA_MOUSE,"Trifunctional enzyme subunit alpha, mitochondrial",GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,KEGG:mmu:97212`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^9-117^E:1.7e-26,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^12-118^E:1.3e-15,"PF02737.18^3HCDH_N^3-hydroxyacyl-CoA dehydrogenase, NAD binding domain^259-436^E:2.2e-56","PF00725.22^3HCDH^3-hydroxyacyl-CoA dehydrogenase, C-terminal domain^439-534^E:9.7e-26",NA,,
no,AD,DRA,DN6101_c0_g1_i7,DN6101_c0_g1,ECHA_HUMAN,"Trifunctional enzyme subunit alpha, mitochondrial",ECHA_HUMAN,"Trifunctional enzyme subunit alpha, mitochondrial",GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,KEGG:hsa:3030`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^67-244^E:8.6e-40,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^72-245^E:2.4e-24,"PF02737.18^3HCDH_N^3-hydroxyacyl-CoA dehydrogenase, NAD binding domain^386-563^E:3e-56","PF00725.22^3HCDH^3-hydroxyacyl-CoA dehydrogenase, C-terminal domain^566-661^E:1.3e-25",NA,,
no,AD,DRA,DN6101_c0_g1_i3,DN6101_c0_g1,ECHA_MOUSE,"Trifunctional enzyme subunit alpha, mitochondrial",ECHA_HUMAN,"Trifunctional enzyme subunit alpha, mitochondrial",GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,KEGG:hsa:3030`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DRA,DN41978_c1_g2_i2,DN41978_c1_g2,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN41978_c1_g2_i1,DN41978_c1_g2,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i9,DN2400_c1_g1,UXS1_HUMAN,UDP-glucuronic acid decarboxylase 1,UXS1_PONAB,UDP-glucuronic acid decarboxylase 1,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048040^molecular_function^UDP-glucuronate decarboxylase activity,GO:0033320^biological_process^UDP-D-xylose biosynthetic process,NA,KEGG:pon:100173139`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,PF11803.8^UXS1_N^UDP-glucuronate decarboxylase N-terminal^31-103^E:1.3e-38,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^115-288^E:3.8e-08,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^116-341^E:1.3e-49,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^116-222^E:0.00018,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^117-345^E:1.4e-48",,
no,AD,DRA,DN2400_c1_g1_i10,DN2400_c1_g1,UXS1_RAT,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,.,NA,NA,NA,NA,KEGG:rno:246232`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i12,DN2400_c1_g1,UXS1_PONAB,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048040^molecular_function^UDP-glucuronate decarboxylase activity,GO:0033320^biological_process^UDP-D-xylose biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:pon:100173139`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i6,DN2400_c1_g1,UXS1_MOUSE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:67883`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i11,DN2400_c1_g1,UXS1_HUMAN,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,.,NA,NA,NA,NA,KEGG:hsa:80146`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i1,DN2400_c1_g1,UXS1_PONAB,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048040^molecular_function^UDP-glucuronate decarboxylase activity,GO:0033320^biological_process^UDP-D-xylose biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:pon:100173139`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2400_c1_g1_i5,DN2400_c1_g1,UXS1_HUMAN,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,.,NA,NA,NA,NA,KEGG:hsa:80146`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i10,DN2474_c1_g1,NNRD_HUMAN,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},NNRD_HUMAN,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},GO:0005759^cellular_component^mitochondrial matrix,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0034356^biological_process^NAD biosynthesis via nicotinamide riboside salvage pathway,GO:0005759^cellular_component^mitochondrial matrix,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0034356^biological_process^NAD biosynthesis via nicotinamide riboside salvage pathway,KEGG:hsa:55739`KO:K17757,"COG0063^Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)",PF13837.6^Myb_DNA-bind_4^Myb/SANT-like DNA-binding domain^132-219^E:3.2e-20,PF01256.17^Carb_kinase^Carbohydrate kinase^477-687^E:1.2e-52,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i6,DN2474_c1_g1,NNRD_HUMAN,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},NNRD_HUMAN,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},GO:0005759^cellular_component^mitochondrial matrix,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0034356^biological_process^NAD biosynthesis via nicotinamide riboside salvage pathway,GO:0005759^cellular_component^mitochondrial matrix,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0034356^biological_process^NAD biosynthesis via nicotinamide riboside salvage pathway,KEGG:hsa:55739`KO:K17757,"COG0063^Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i2,DN2474_c1_g1,NNRD_MACMU,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},.,NA,GO:0005739^cellular_component^mitochondrion,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,.,NA,NA,NA,NA,.,"COG0063^Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i9,DN2474_c1_g1,NNRD_PONAB,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},.,NA,GO:0005739^cellular_component^mitochondrion,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,.,NA,NA,NA,NA,KEGG:pon:100173186`KO:K17757,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i7,DN2474_c1_g1,NNRD_PONAB,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},NNRD_DANRE,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},GO:0005739^cellular_component^mitochondrion,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,NA,KEGG:pon:100173186`KO:K17757,"COG0063^Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)",PF01256.17^Carb_kinase^Carbohydrate kinase^1-159^E:8e-31,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i8,DN2474_c1_g1,NNRD_PONAB,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},NNRD_HUMAN,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},GO:0005739^cellular_component^mitochondrion,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0034356^biological_process^NAD biosynthesis via nicotinamide riboside salvage pathway,KEGG:hsa:55739`KO:K17757,"COG0063^Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)",PF01256.17^Carb_kinase^Carbohydrate kinase^94-304^E:1.8e-53,NA,NA,NA,NA,,
no,AD,DRA,DN2474_c1_g1_i5,DN2474_c1_g1,NNRD_PONAB,ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157},.,NA,GO:0005739^cellular_component^mitochondrion,GO:0052855^molecular_function^ADP-dependent NAD(P)H-hydrate dehydratase activity,GO:0005524^molecular_function^ATP binding,GO:0047453^molecular_function^ATP-dependent NAD(P)H-hydrate dehydratase activity,GO:0046496^biological_process^nicotinamide nucleotide metabolic process,.,NA,NA,NA,NA,KEGG:pon:100173186`KO:K17757,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN55589_c0_g1_i3,DN55589_c0_g1,HUTU_MOUSE,Urocanate hydratase,HUTU_MOUSE,Urocanate hydratase,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,KEGG:mmu:243537`KO:K01712,COG2987^Urocanate hydratase,PF17392.2^Urocanase_C^Urocanase C-terminal domain^3-210^E:1.3e-89,NA,NA,NA,NA,,
no,AD,DRA,DN55589_c0_g1_i1,DN55589_c0_g1,HUTU_MOUSE,Urocanate hydratase,HUTU_MOUSE,Urocanate hydratase,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,KEGG:mmu:243537`KO:K01712,COG2987^Urocanate hydratase,PF01175.18^Urocanase^Urocanase Rossmann-like domain^2-151^E:4.8e-48,PF17392.2^Urocanase_C^Urocanase C-terminal domain^154-352^E:1.5e-86,NA,NA,NA,,
no,AD,DRA,DN55589_c0_g1_i2,DN55589_c0_g1,HUTU_MOUSE,Urocanate hydratase,HUTU_MOUSE,Urocanate hydratase,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,KEGG:mmu:243537`KO:K01712,COG2987^Urocanate hydratase,PF01175.18^Urocanase^Urocanase Rossmann-like domain^2-151^E:6e-48,PF17392.2^Urocanase_C^Urocanase C-terminal domain^154-361^E:6.1e-89,NA,NA,NA,,
no,AD,DRA,DN63887_c1_g1_i1,DN63887_c1_g1,PYGB_RAT,"Glycogen phosphorylase, brain form",.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,.,NA,NA,NA,NA,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN28475_c1_g1_i2,DN28475_c1_g1,PYGL_HUMAN,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,.,NA,NA,NA,NA,KEGG:hsa:5836`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN28475_c2_g1_i2,DN28475_c2_g1,PYGB_RAT,"Glycogen phosphorylase, brain form",.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0030246^molecular_function^carbohydrate binding,GO:0008144^molecular_function^drug binding,GO:0008184^molecular_function^glycogen phosphorylase activity,.,NA,NA,NA,NA,KEGG:rno:25739`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN28475_c3_g1_i1,DN28475_c3_g1,PYGL_HUMAN,"Glycogen phosphorylase, liver form",PYGL_HUMAN,"Glycogen phosphorylase, liver form",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,KEGG:hsa:5836`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^21-59^E:4.8e-18,NA,NA,NA,NA,,
no,AD,DRA,DN80080_c0_g1_i1,DN80080_c0_g1,NDUA9_RAT,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003954^molecular_function^NADH dehydrogenase activity,.,NA,NA,NA,NA,KEGG:rno:362440`KO:K03953,COG0702^epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i8,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-160^E:3.6e-40,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i1,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-112^E:6.1e-20,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i4,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-153^E:6.1e-40,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i7,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,.,NA,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,.,NA,NA,NA,NA,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i6,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-112^E:1e-19,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i9,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,.,NA,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,.,NA,NA,NA,NA,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i10,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-112^E:7.7e-20,NA,NA,NA,NA,,
no,AD,DRA,DN18670_c0_g1_i3,DN18670_c0_g1,CAH13_HUMAN,Carbonic anhydrase 13,CAH13_HUMAN,Carbonic anhydrase 13,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043209^cellular_component^myelin sheath,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,KEGG:hsa:377677`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^40-153^E:7.3e-40,NA,NA,NA,NA,,
no,AD,DRA,DN35934_c0_g1_i4,DN35934_c0_g1,VDRA_DANRE,Vitamin D3 receptor A,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:1902098^molecular_function^calcitriol binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:dre:30076`KO:K08539,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN10516_c0_g1_i4,DN10516_c0_g1,BTD_MOUSE,Biotinidase,BTD_MOUSE,Biotinidase,GO:0045177^cellular_component^apical part of cell,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0043204^cellular_component^perikaryon,GO:0047708^molecular_function^biotinidase activity,GO:0045177^cellular_component^apical part of cell,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0043204^cellular_component^perikaryon,GO:0047708^molecular_function^biotinidase activity,KEGG:mmu:26363`KO:K01435,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,PF00795.22^CN_hydrolase^Carbon-nitrogen hydrolase^62-233^E:4.2e-15,NA,NA,NA,NA,,
no,AD,DRA,DN26921_c2_g1_i1,DN26921_c2_g1,NADE_CHICK,Glutamine-dependent NAD(+) synthetase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0004359^molecular_function^glutaminase activity,GO:0003952^molecular_function^NAD+ synthase (glutamine-hydrolyzing) activity,GO:0009435^biological_process^NAD biosynthetic process,.,NA,NA,NA,NA,KEGG:gga:422983`KO:K01950,COG0171^nh(3)-dependent nad( ) synthetase`COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN93985_c0_g2_i2,DN93985_c0_g2,PHS2_HUMAN,Pterin-4-alpha-carbinolamine dehydratase 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0004505^molecular_function^phenylalanine 4-monooxygenase activity,"GO:0045893^biological_process^positive regulation of transcription, DNA-templated",GO:0051291^biological_process^protein heterooligomerization,.,NA,NA,NA,NA,KEGG:hsa:84105`KO:K01724,COG2154^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN1890_c0_g1_i4,DN1890_c0_g1,PYGL_RAT,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,.,NA,NA,NA,NA,KEGG:rno:64035`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN1890_c0_g1_i8,DN1890_c0_g1,PYGL_RAT,"Glycogen phosphorylase, liver form",PYGL_RAT,"Glycogen phosphorylase, liver form",GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,KEGG:rno:64035`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^114-828^E:0,NA,NA,NA,NA,,
no,AD,DRA,DN1890_c0_g1_i6,DN1890_c0_g1,PYGL_RAT,"Glycogen phosphorylase, liver form",PYGL_RAT,"Glycogen phosphorylase, liver form",GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,KEGG:rno:64035`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^114-828^E:0,NA,NA,NA,NA,,
no,AD,DRA,DN1890_c0_g1_i5,DN1890_c0_g1,PYGL_RAT,"Glycogen phosphorylase, liver form",PYGL_RAT,"Glycogen phosphorylase, liver form",GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,GO:0005737^cellular_component^cytoplasm,GO:0016208^molecular_function^AMP binding,GO:0005524^molecular_function^ATP binding,GO:0032052^molecular_function^bile acid binding,GO:0030246^molecular_function^carbohydrate binding,KEGG:rno:64035`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^114-828^E:0,NA,NA,NA,NA,,
no,AD,DRA,DN51407_c0_g1_i2,DN51407_c0_g1,HIBCH_CHICK,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003860^molecular_function^3-hydroxyisobutyryl-CoA hydrolase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0006574^biological_process^valine catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:423979`KO:K05605,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN67742_c0_g1_i1,DN67742_c0_g1,VNN3_HUMAN,Vascular non-inflammatory molecule 3,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,.,NA,NA,NA,NA,KEGG:hsa:55350`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN33301_c0_g1_i1,DN33301_c0_g1,ACON_BOVIN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1061_c2_g1_i2,DN1061_c2_g1,ENOG_RAT,Gamma-enolase,.,NA,GO:0099738^cellular_component^cell cortex region,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0030426^cellular_component^growth cone,GO:0045121^cellular_component^membrane raft,.,NA,NA,NA,NA,KEGG:rno:100911625`KEGG:rno:24334`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN1003_c1_g2_i3,DN1003_c1_g2,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,KEGG:hsa:23600`KO:K01796,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^1-266^E:1.6e-52,NA,NA,NA,NA,,
no,AD,DRA,DN1003_c1_g2_i2,DN1003_c1_g2,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,KEGG:hsa:23600`KO:K01796,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^14-197^E:7.3e-56,NA,NA,NA,NA,,
no,AD,DRA,DN1003_c1_g2_i4,DN1003_c1_g2,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,AMACR_HUMAN,Alpha-methylacyl-CoA racemase,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005782^cellular_component^peroxisomal matrix,KEGG:hsa:23600`KO:K01796,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^14-362^E:1.2e-80,NA,NA,NA,NA,,
no,AD,DRA,DN1003_c1_g2_i1,DN1003_c1_g2,AMACR_RAT,Alpha-methylacyl-CoA racemase,AMACR_RAT,Alpha-methylacyl-CoA racemase,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0008111^molecular_function^alpha-methylacyl-CoA racemase activity,GO:0008410^molecular_function^CoA-transferase activity,GO:0006699^biological_process^bile acid biosynthetic process,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0008111^molecular_function^alpha-methylacyl-CoA racemase activity,GO:0008410^molecular_function^CoA-transferase activity,GO:0006699^biological_process^bile acid biosynthetic process,.,COG1804^l-carnitine dehydratase bile acid-inducible protein F,PF02515.17^CoA_transf_3^CoA-transferase family III^14-96^E:1.9e-20,NA,NA,NA,NA,,
no,AD,DRA,DN41585_c0_g1_i2,DN41585_c0_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^1-210^E:2e-53,NA,NA,NA,NA,,
no,AD,DRA,DN41585_c0_g1_i1,DN41585_c0_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,.,NA,NA,NA,NA,,
no,AD,DRA,DN41585_c0_g1_i5,DN41585_c0_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^97-333^E:2.5e-68,NA,NA,NA,NA,,
no,AD,DRA,DN41585_c0_g1_i4,DN41585_c0_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^97-333^E:2.5e-68,NA,NA,NA,NA,,
no,AD,DRA,DN41585_c0_g1_i3,DN41585_c0_g1,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,CHSTB_HUMAN,Carbohydrate sulfotransferase 11,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0001537^molecular_function^N-acetylgalactosamine 4-O-sulfotransferase activity,KEGG:hsa:50515`KO:K01017,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^1-210^E:2e-53,NA,NA,NA,NA,,
no,AD,DRA,DN15230_c0_g1_i3,DN15230_c0_g1,CAH7_HUMAN,Carbonic anhydrase 7,.,NA,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0032849^biological_process^positive regulation of cellular pH reduction,.,NA,NA,NA,NA,KEGG:hsa:766`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN5866_c1_g1_i5,DN5866_c1_g1,TGDS_HUMAN,"dTDP-D-glucose 4,6-dehydratase",TGDS_HUMAN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:hsa:23483`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-277^E:4.6e-23,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-279^E:7.7e-26,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-274^E:1.3e-64",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-258^E:2.7e-61,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-243^E:1.9e-25,,
no,AD,DRA,DN5866_c1_g1_i6,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",TGDS_HUMAN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:hsa:23483`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^6-82^E:3.7e-18,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^6-99^E:9.7e-14",NA,NA,NA,,
no,AD,DRA,DN5866_c1_g1_i4,DN5866_c1_g1,TGDS_HUMAN,"dTDP-D-glucose 4,6-dehydratase",TGDS_HUMAN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:hsa:23483`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-327^E:1.6e-25,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-284^E:2e-26,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-327^E:1.6e-72",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-258^E:5.2e-61,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-243^E:3.5e-25,,
no,AD,DRA,DN5866_c1_g1_i11,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-329^E:4.2e-26,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-285^E:2.1e-26,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-327^E:1.8e-72",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-258^E:5.7e-61,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-243^E:3.8e-25,,
no,AD,DRA,DN5866_c1_g1_i7,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-185^E:3e-19,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-145^E:1.2e-18,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-186^E:1.9e-45",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-186^E:1.2e-37,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-178^E:1.4e-21,,
no,AD,DRA,DN5866_c1_g1_i12,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",.,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN5866_c1_g1_i10,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",.,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN5866_c1_g1_i14,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-185^E:3e-19,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-145^E:1.2e-18,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-186^E:1.9e-45",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-186^E:1.2e-37,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-178^E:1.4e-21,,
no,AD,DRA,DN5866_c1_g1_i2,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",.,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN5866_c1_g1_i8,DN5866_c1_g1,TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase",TGDS_BOVIN,"dTDP-D-glucose 4,6-dehydratase","GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,"GO:0008460^molecular_function^dTDP-glucose 4,6-dehydratase activity",GO:0009225^biological_process^nucleotide-sugar metabolic process,NA,NA,NA,KEGG:bta:534594`KO:K01710,COG1088^dTDP-glucose 4-6-dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^19-185^E:3e-19,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^20-145^E:1.2e-18,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^21-186^E:1.9e-45",PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^21-186^E:1.2e-37,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^21-178^E:1.4e-21,,
no,AD,DRA,DN91371_c0_g1_i1,DN91371_c0_g1,PTPRG_MOUSE,Receptor-type tyrosine-protein phosphatase gamma,.,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042802^molecular_function^identical protein binding,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0010633^biological_process^negative regulation of epithelial cell migration,.,NA,NA,NA,NA,KEGG:mmu:19270`KO:K16667,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,.,NA,NA,NA,NA,,
no,AD,DRA,DN39849_c0_g1_i4,DN39849_c0_g1,HIBCH_CHICK,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003860^molecular_function^3-hydroxyisobutyryl-CoA hydrolase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0006574^biological_process^valine catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:423979`KO:K05605,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN39849_c0_g1_i5,DN39849_c0_g1,HIBCH_CHICK,"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003860^molecular_function^3-hydroxyisobutyryl-CoA hydrolase activity,GO:0006635^biological_process^fatty acid beta-oxidation,GO:0006574^biological_process^valine catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:423979`KO:K05605,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN4997_c0_g1_i2,DN4997_c0_g1,YDJC_XENLA,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},YDJC_XENLA,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},GO:0016787^molecular_function^hydrolase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,GO:0016787^molecular_function^hydrolase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xla:734411,.,PF04794.12^YdjC^YdjC-like protein^5-296^E:3e-65,NA,NA,NA,NA,,
no,AD,DRA,DN4997_c0_g1_i8,DN4997_c0_g1,YDJC_DANRE,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},YDJC_XENTR,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},GO:0019213^molecular_function^deacetylase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,GO:0019213^molecular_function^deacetylase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,KEGG:xtr:448202,COG3394^UPF0249 protein,.,NA,NA,NA,NA,,
no,AD,DRA,DN4997_c0_g1_i3,DN4997_c0_g1,YDJC_XENLA,Carbohydrate deacetylase {ECO:0000250|UniProtKB:Q53WD3},.,NA,GO:0016787^molecular_function^hydrolase activity,GO:0000287^molecular_function^magnesium ion binding,GO:0005975^biological_process^carbohydrate metabolic process,NA,NA,.,NA,NA,NA,NA,KEGG:xla:734411,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN5001_c0_g1_i4,DN5001_c0_g1,HTD2_HUMAN,"Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}",RPP14_PONAB,Ribonuclease P protein subunit p14,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0018812^molecular_function^3-hydroxyacyl-CoA dehydratase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0030681^cellular_component^multimeric ribonuclease P complex,GO:0005730^cellular_component^nucleolus,GO:0004526^molecular_function^ribonuclease P activity,GO:0033204^molecular_function^ribonuclease P RNA binding,GO:0001682^biological_process^tRNA 5'-leader removal,KEGG:pon:100174423`KO:K14529,ENOG4112ADM^Ribonuclease P MRP 14kDa subunit,PF01900.19^RNase_P_Rpp14^Rpp14/Pop5 family^34-121^E:1.2e-10,NA,NA,NA,NA,,
no,AD,DRA,DN5001_c0_g1_i1,DN5001_c0_g1,HTD2_HUMAN,"Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}",HTD2_HUMAN,"Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0018812^molecular_function^3-hydroxyacyl-CoA dehydratase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0018812^molecular_function^3-hydroxyacyl-CoA dehydratase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:109703458`KO:K22540,COG2030^maoc domain protein dehydratase,PF01575.19^MaoC_dehydratas^MaoC like domain^45-153^E:3.3e-21,PF13452.6^MaoC_dehydrat_N^N-terminal half of MaoC dehydratase^49-137^E:2.1e-07,PF03061.22^4HBT^Thioesterase superfamily^98-147^E:0.0002,NA,NA,,
no,AD,DRA,DN5001_c0_g1_i8,DN5001_c0_g1,HTD2_HUMAN,"Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}",HTD2_HUMAN,"Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0018812^molecular_function^3-hydroxyacyl-CoA dehydratase activity,GO:0006631^biological_process^fatty acid metabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005730^cellular_component^nucleolus,GO:0018812^molecular_function^3-hydroxyacyl-CoA dehydratase activity,GO:0006631^biological_process^fatty acid metabolic process,KEGG:hsa:109703458`KO:K22540,COG2030^maoc domain protein dehydratase,PF01575.19^MaoC_dehydratas^MaoC like domain^45-153^E:3.3e-21,PF13452.6^MaoC_dehydrat_N^N-terminal half of MaoC dehydratase^49-137^E:2.1e-07,PF03061.22^4HBT^Thioesterase superfamily^98-147^E:0.0002,NA,NA,,
no,AD,DRA,DN22686_c1_g1_i1,DN22686_c1_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN22686_c2_g1_i1,DN22686_c2_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13667_c0_g1_i8,DN13667_c0_g1,UXS1_MOUSE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:67883`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13667_c0_g1_i7,DN13667_c0_g1,UXS1_MOUSE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:67883`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN20028_c0_g1_i3,DN20028_c0_g1,VNN1_BOVIN,Pantetheinase,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,NA,.,NA,NA,NA,NA,KEGG:bta:526704`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN70934_c0_g1_i1,DN70934_c0_g1,DTHAD_DELSH,D-threo-3-hydroxyaspartate dehydratase,DTHAD_DELSH,D-threo-3-hydroxyaspartate dehydratase,GO:0016841^molecular_function^ammonia-lyase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,NA,NA,NA,GO:0016841^molecular_function^ammonia-lyase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,NA,NA,NA,KEGG:ag:BAG24498`KO:K20757,.,"PF01168.20^Ala_racemase_N^Alanine racemase, N-terminal domain^17-168^E:1.3e-13",PF14031.6^D-ser_dehydrat^Putative serine dehydratase domain^184-280^E:7.2e-19,NA,NA,NA,,
no,AD,DRA,DN17461_c0_g2_i3,DN17461_c0_g2,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,KEGG:mmu:71712`KO:K21955,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^19-193^E:1.2e-36,NA,NA,NA,NA,,
no,AD,DRA,DN17461_c0_g2_i4,DN17461_c0_g2,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,KEGG:mmu:71712`KO:K21955,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^19-124^E:3.2e-23,NA,NA,NA,NA,,
no,AD,DRA,DN17461_c0_g2_i6,DN17461_c0_g2,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,KEGG:mmu:71712`KO:K21955,ENOG4111KNB^DNA-damage regulated autophagy modulator,PF10277.9^Frag1^Frag1/DRAM/Sfk1 family^19-235^E:6e-49,NA,NA,NA,NA,,
no,AD,DRA,DN17461_c0_g2_i1,DN17461_c0_g2,DRAM1_MOUSE,DNA damage-regulated autophagy modulator protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,KEGG:mmu:71712`KO:K21955,ENOG4111KNB^DNA-damage regulated autophagy modulator,.,NA,NA,NA,NA,,
no,AD,DRA,DN16636_c0_g1_i3,DN16636_c0_g1,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:59031`KO:K04742,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^160-411^E:1.9e-63,NA,NA,NA,NA,,
no,AD,DRA,DN16636_c0_g1_i1,DN16636_c0_g1,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:59031`KO:K04742,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^160-411^E:1.9e-63,NA,NA,NA,NA,,
no,AD,DRA,DN16636_c0_g1_i2,DN16636_c0_g1,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:mmu:59031`KO:K04742,ENOG4111GJR^carbohydrate,PF03567.14^Sulfotransfer_2^Sulfotransferase family^160-411^E:1.9e-63,NA,NA,NA,NA,,
no,AD,DRA,DN16636_c0_g1_i4,DN16636_c0_g1,CHSTC_MOUSE,Carbohydrate sulfotransferase 12,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0047756^molecular_function^chondroitin 4-sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0016051^biological_process^carbohydrate biosynthetic process,.,NA,NA,NA,NA,KEGG:mmu:59031`KO:K04742,ENOG4111GJR^carbohydrate,.,NA,NA,NA,NA,,
no,AD,DRA,DN9343_c2_g1_i1,DN9343_c2_g1,CDYL2_HUMAN,Chromodomain Y-like protein 2,CDYL2_HUMAN,Chromodomain Y-like protein 2,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,KEGG:hsa:124359`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^96-145^E:6.6e-17,NA,NA,NA,NA,,
no,AD,DRA,DN9343_c2_g1_i3,DN9343_c2_g1,CDYL2_HUMAN,Chromodomain Y-like protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,.,NA,NA,NA,NA,KEGG:hsa:124359`KO:K00653,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN9343_c2_g1_i2,DN9343_c2_g1,CDYL2_HUMAN,Chromodomain Y-like protein 2,CDYL2_HUMAN,Chromodomain Y-like protein 2,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,KEGG:hsa:124359`KO:K00653,COG1024^Enoyl-CoA hydratase,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^96-145^E:6.4e-17,NA,NA,NA,NA,,
no,AD,DRA,DN9343_c2_g1_i6,DN9343_c2_g1,CDYL2_HUMAN,Chromodomain Y-like protein 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0003824^molecular_function^catalytic activity,GO:0035064^molecular_function^methylated histone binding,GO:0003714^molecular_function^transcription corepressor activity,NA,.,NA,NA,NA,NA,KEGG:hsa:124359`KO:K00653,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN9330_c0_g1_i6,DN9330_c0_g1,CHST3_CHICK,Carbohydrate sulfotransferase 3,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0008459^molecular_function^chondroitin 6-sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:gga:396018`KO:K01020,ENOG410YDA4^Carbohydrate (Chondroitin 6) sulfotransferase 3,.,NA,NA,NA,NA,,
no,AD,DRA,DN9330_c0_g1_i1,DN9330_c0_g1,CHST3_CHICK,Carbohydrate sulfotransferase 3,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0008459^molecular_function^chondroitin 6-sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:gga:396018`KO:K01020,ENOG410YDA4^Carbohydrate (Chondroitin 6) sulfotransferase 3,.,NA,NA,NA,NA,,
no,AD,DRA,DN9330_c0_g1_i8,DN9330_c0_g1,CHST3_CHICK,Carbohydrate sulfotransferase 3,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005802^cellular_component^trans-Golgi network,GO:0008459^molecular_function^chondroitin 6-sulfotransferase activity,GO:0001517^molecular_function^N-acetylglucosamine 6-O-sulfotransferase activity,.,NA,NA,NA,NA,KEGG:gga:396018`KO:K01020,ENOG410YDA4^Carbohydrate (Chondroitin 6) sulfotransferase 3,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i14,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i5,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^452-506^E:7.9e-13,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i10,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i12,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i8,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,.,NA,NA,NA,NA,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i18,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^680-734^E:1.3e-12,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i17,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:51085`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^65-193^E:3.3e-09,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i6,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,.,NA,NA,NA,NA,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i2,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:51085`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^52-180^E:2.8e-09,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i7,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_RAT,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^452-506^E:7.9e-13,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i4,DN1650_c0_g1,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,MLXPL_HUMAN,Carbohydrate-responsive element-binding protein,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:51085`KO:K09113,ENOG410XTA5^MLX interacting,PF00010.26^HLH^Helix-loop-helix DNA-binding domain^328-382^E:7.9e-13,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i1,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,.,NA,NA,NA,NA,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1650_c0_g1_i13,DN1650_c0_g1,MLXPL_RAT,Carbohydrate-responsive element-binding protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0035538^molecular_function^carbohydrate response element binding,.,NA,NA,NA,NA,KEGG:rno:171078`KO:K09113,ENOG410XTA5^MLX interacting,.,NA,NA,NA,NA,,
no,AD,DRA,DN1681_c0_g1_i8,DN1681_c0_g1,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",KEGG:hsa:80270`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^3-105^E:9.5e-27,NA,NA,NA,NA,,
no,AD,DRA,DN1681_c0_g1_i3,DN1681_c0_g1,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",KEGG:hsa:80270`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^6-81^E:1.6e-15,NA,NA,NA,NA,,
no,AD,DRA,DN1681_c0_g1_i2,DN1681_c0_g1,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",.,NA,NA,NA,NA,KEGG:hsa:80270`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1681_c0_g1_i7,DN1681_c0_g1,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",.,NA,NA,NA,NA,KEGG:hsa:80270`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN1681_c0_g1_i5,DN1681_c0_g1,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,3BHS7_HUMAN,3 beta-hydroxysteroid dehydrogenase type 7,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,"GO:0047016^molecular_function^cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",KEGG:hsa:80270`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^3-105^E:9.5e-27,NA,NA,NA,NA,,
no,AD,DRA,DN8470_c0_g1_i2,DN8470_c0_g1,T3HPD_HUMAN,"Trans-3-hydroxy-L-proline dehydratase {ECO:0000303|PubMed:22528483, ECO:0000303|PubMed:24649405}",T3HPD_HUMAN,"Trans-3-hydroxy-L-proline dehydratase {ECO:0000303|PubMed:22528483, ECO:0000303|PubMed:24649405}",GO:0016836^molecular_function^hydro-lyase activity,GO:0050346^molecular_function^trans-L-3-hydroxyproline dehydratase activity,NA,NA,NA,GO:0016836^molecular_function^hydro-lyase activity,GO:0050346^molecular_function^trans-L-3-hydroxyproline dehydratase activity,NA,NA,NA,KEGG:hsa:112849`KO:K18384,COG3938^Proline racemase,PF05544.11^Pro_racemase^Proline racemase^40-373^E:2.7e-93,NA,NA,NA,NA,,
no,AD,DRA,DN8470_c0_g1_i3,DN8470_c0_g1,T3HPD_XENTR,Trans-L-3-hydroxyproline dehydratase,.,NA,GO:0016836^molecular_function^hydro-lyase activity,GO:0050346^molecular_function^trans-L-3-hydroxyproline dehydratase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xtr:493490`KO:K18384,COG3938^Proline racemase,.,NA,NA,NA,NA,,
no,AD,DRA,DN8431_c0_g1_i3,DN8431_c0_g1,ENOG_CHICK,Gamma-enolase,.,NA,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,.,NA,NA,NA,NA,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN8431_c0_g1_i5,DN8431_c0_g1,ENOG_CHICK,Gamma-enolase,ENOG_CHICK,Gamma-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^2-54^E:2e-21","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^63-276^E:6.6e-112",NA,NA,NA,,
no,AD,DRA,DN8431_c0_g1_i7,DN8431_c0_g1,ENOG_CHICK,Gamma-enolase,ENOG_CHICK,Gamma-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^2-54^E:2e-21","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^63-276^E:6.6e-112",NA,NA,NA,,
no,AD,DRA,DN8431_c0_g1_i2,DN8431_c0_g1,ENOG_CHICK,Gamma-enolase,ENOG_CHICK,Gamma-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^55-108^E:1.2e-21","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^117-404^E:4.2e-158",PF13378.6^MR_MLE_C^Enolase C-terminal domain-like^259-345^E:3.7e-09,PF07476.11^MAAL_C^Methylaspartate ammonia-lyase C-terminus^283-364^E:7e-05,NA,,
no,AD,DRA,DN8431_c0_g1_i4,DN8431_c0_g1,ENOG_CHICK,Gamma-enolase,ENOG_CHICK,Gamma-enolase,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),"PF03952.16^Enolase_N^Enolase, N-terminal domain^55-186^E:2.5e-59","PF00113.22^Enolase_C^Enolase, C-terminal TIM barrel domain^195-482^E:7e-158",PF13378.6^MR_MLE_C^Enolase C-terminal domain-like^337-423^E:5.3e-09,PF07476.11^MAAL_C^Methylaspartate ammonia-lyase C-terminus^361-442^E:9.3e-05,NA,,
no,AD,DRA,DN8431_c0_g2_i1,DN8431_c0_g2,ENOG_CHICK,Gamma-enolase,.,NA,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,.,NA,NA,NA,NA,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN56686_c0_g1_i1,DN56686_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,.,NA,NA,NA,NA,,
no,AD,DRA,DN56686_c0_g1_i3,DN56686_c0_g1,CHSTF_HUMAN,Carbohydrate sulfotransferase 15,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0050656^molecular_function^3'-phosphoadenosine 5'-phosphosulfate binding,GO:0050659^molecular_function^N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,GO:0030206^biological_process^chondroitin sulfate biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:51363`KO:K08106,ENOG410XSMU^Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,.,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i15,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^31-155^E:2e-08,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^33-164^E:3.2e-27,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^33-163^E:1.7e-17,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^33-145^E:5.4e-08,PF13460.6^NAD_binding_10^NAD(P)H-binding^36-146^E:5.9e-09,,
no,AD,DRA,DN14023_c0_g1_i16,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i18,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^31-155^E:2e-08,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^33-164^E:3.2e-27,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^33-163^E:1.7e-17,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^33-145^E:5.4e-08,PF13460.6^NAD_binding_10^NAD(P)H-binding^36-146^E:5.9e-09,,
no,AD,DRA,DN14023_c0_g1_i8,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i10,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i3,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^31-211^E:3.8e-10,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^33-299^E:5e-65,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^33-261^E:2.2e-31,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^33-145^E:2.7e-07,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^34-285^E:1.8e-14",,
no,AD,DRA,DN14023_c0_g1_i17,DN14023_c0_g1,VWA3A_HUMAN,von Willebrand factor A domain-containing protein 3A,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,KEGG:hsa:146177,COG0451^Nad-dependent epimerase dehydratase,PF04321.17^RmlD_sub_bind^RmlD substrate binding domain^31-211^E:1.7e-10,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^33-289^E:1.4e-62,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^33-261^E:8.8e-32,PF02719.15^Polysacc_synt_2^Polysaccharide biosynthesis protein^33-145^E:1.5e-07,"PF16363.5^GDP_Man_Dehyd^GDP-mannose 4,6 dehydratase^34-285^E:7.8e-15",,
no,AD,DRA,DN14023_c0_g1_i14,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^2-60^E:1.3e-09,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i6,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^2-60^E:1.3e-09,NA,NA,NA,NA,,
no,AD,DRA,DN14023_c0_g1_i19,DN14023_c0_g1,D42E2_HUMAN,Putative short-chain dehydrogenase/reductase family 42E member 2,.,NA,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0016491^molecular_function^oxidoreductase activity,"GO:0016616^molecular_function^oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",GO:0006694^biological_process^steroid biosynthetic process,NA,.,NA,NA,NA,NA,.,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN90124_c0_g1_i1,DN90124_c0_g1,PTPRG_MOUSE,Receptor-type tyrosine-protein phosphatase gamma,.,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042802^molecular_function^identical protein binding,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0010633^biological_process^negative regulation of epithelial cell migration,.,NA,NA,NA,NA,KEGG:mmu:19270`KO:K16667,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,.,NA,NA,NA,NA,,
no,AD,DRA,DN13210_c0_g2_i1,DN13210_c0_g2,ECHD3_HUMAN,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000305}",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003824^molecular_function^catalytic activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:79746,ENOG410XPEY^Enoyl-CoA hydratase/isomerase family,.,NA,NA,NA,NA,,
no,AD,DRA,DN13210_c0_g3_i1,DN13210_c0_g3,ECHD3_XENLA,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0003824^molecular_function^catalytic activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xla:100127325,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN13210_c0_g4_i1,DN13210_c0_g4,ECHD3_RAT,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000305}",ECHD3_RAT,"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000305}",GO:0005739^cellular_component^mitochondrion,GO:0003824^molecular_function^catalytic activity,NA,NA,NA,GO:0005739^cellular_component^mitochondrion,GO:0003824^molecular_function^catalytic activity,NA,NA,NA,KEGG:rno:684538,ENOG410XPEY^Enoyl-CoA hydratase/isomerase family,PF00378.20^ECH_1^Enoyl-CoA hydratase/isomerase^39-285^E:2.3e-54,PF16113.5^ECH_2^Enoyl-CoA hydratase/isomerase^43-224^E:3.2e-32,NA,NA,NA,,
no,AD,DRA,DN129055_c0_g1_i1,DN129055_c0_g1,3BHS7_MOUSE,3 beta-hydroxysteroid dehydrogenase type 7,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:mmu:101502`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN129055_c0_g1_i2,DN129055_c0_g1,3BHS7_MOUSE,3 beta-hydroxysteroid dehydrogenase type 7,3BHS7_MOUSE,3 beta-hydroxysteroid dehydrogenase type 7,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,KEGG:mmu:101502`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,PF01073.19^3Beta_HSD^3-beta hydroxysteroid dehydrogenase/isomerase family^1-138^E:2e-41,PF07993.12^NAD_binding_4^Male sterility protein^1-93^E:9.3e-06,PF01370.21^Epimerase^NAD dependent epimerase/dehydratase family^2-136^E:7.1e-07,NA,NA,,
no,AD,DRA,DN111490_c0_g1_i1,DN111490_c0_g1,UXS1_MOUSE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:mmu:67883`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN185980_c0_g1_i1,DN185980_c0_g1,PHS2_HUMAN,Pterin-4-alpha-carbinolamine dehydratase 2,.,NA,GO:0005634^cellular_component^nucleus,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0004505^molecular_function^phenylalanine 4-monooxygenase activity,"GO:0045893^biological_process^positive regulation of transcription, DNA-templated",GO:0051291^biological_process^protein heterooligomerization,.,NA,NA,NA,NA,KEGG:hsa:84105`KO:K01724,COG2154^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN187672_c0_g1_i1,DN187672_c0_g1,ECHA_RAT,"Trifunctional enzyme subunit alpha, mitochondrial",.,NA,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,.,NA,NA,NA,NA,KEGG:rno:170670`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DRA,DN193154_c0_g1_i1,DN193154_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,.,NA,NA,NA,NA,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN170736_c0_g1_i1,DN170736_c0_g1,PYGM_BOVIN,"Glycogen phosphorylase, muscle form",PYGM_SHEEP,"Glycogen phosphorylase, muscle form",GO:0005737^cellular_component^cytoplasm,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,GO:0000166^molecular_function^nucleotide binding,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,GO:0030170^molecular_function^pyridoxal phosphate binding,GO:0102499^molecular_function^SHG alpha-glucan phosphorylase activity,GO:0005980^biological_process^glycogen catabolic process,KEGG:oas:442998`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^1-134^E:1.9e-50,NA,NA,NA,NA,,
no,AD,DRA,DN137476_c0_g1_i1,DN137476_c0_g1,DSD1_SCHPO,D-serine dehydratase,DSD1_SCHPO,D-serine dehydratase,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008721^molecular_function^D-serine ammonia-lyase activity,GO:0036088^biological_process^D-serine catabolic process,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0008721^molecular_function^D-serine ammonia-lyase activity,GO:0036088^biological_process^D-serine catabolic process,NA,KEGG:spo:SPAC1039.06`KO:K20498,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN163029_c0_g1_i1,DN163029_c0_g1,3BHS7_MOUSE,3 beta-hydroxysteroid dehydrogenase type 7,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:mmu:101502`KO:K12408,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN155842_c0_g1_i2,DN155842_c0_g1,HEM2_PONAB,Delta-aminolevulinic acid dehydratase,.,NA,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:pon:100174182`KO:K01698,COG0113^delta-aminolevulinic acid dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN155842_c0_g1_i1,DN155842_c0_g1,HEM2_PONAB,Delta-aminolevulinic acid dehydratase,.,NA,GO:0004655^molecular_function^porphobilinogen synthase activity,GO:0008270^molecular_function^zinc ion binding,GO:0006783^biological_process^heme biosynthetic process,GO:0006782^biological_process^protoporphyrinogen IX biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:pon:100174182`KO:K01698,COG0113^delta-aminolevulinic acid dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN105298_c0_g1_i2,DN105298_c0_g1,HUTU_MOUSE,Urocanate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,.,NA,NA,NA,NA,KEGG:mmu:243537`KO:K01712,COG2987^Urocanate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN105298_c0_g2_i1,DN105298_c0_g2,HUTU_MOUSE,Urocanate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,.,NA,NA,NA,NA,KEGG:mmu:243537`KO:K01712,COG2987^Urocanate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN111611_c0_g1_i1,DN111611_c0_g1,VNN2_HUMAN,Vascular non-inflammatory molecule 2,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0017159^molecular_function^pantetheine hydrolase activity,GO:0015939^biological_process^pantothenate metabolic process,.,NA,NA,NA,NA,KEGG:hsa:8875`KO:K08069,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN127311_c0_g1_i3,DN127311_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",.,NA,GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",.,NA,NA,NA,NA,KEGG:hsa:50`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN127311_c0_g1_i1,DN127311_c0_g1,ACON_HUMAN,"Aconitate hydratase, mitochondrial",ACON_BOVIN,"Aconitate hydratase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,KEGG:bta:280976`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN172771_c0_g1_i1,DN172771_c0_g1,CAH3_PIG,Carbonic anhydrase 3,.,NA,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0016151^molecular_function^nickel cation binding,GO:0008270^molecular_function^zinc ion binding,GO:0009617^biological_process^response to bacterium,.,NA,NA,NA,NA,KEGG:ssc:494016`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN120707_c0_g1_i1,DN120707_c0_g1,IREB2_CHICK,Iron-responsive element-binding protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,GO:0030350^molecular_function^iron-responsive element binding,.,NA,NA,NA,NA,KEGG:gga:427490`KO:K22416,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN128146_c0_g1_i1,DN128146_c0_g1,NSDHL_BOVIN,"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating",.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005811^cellular_component^lipid droplet,GO:0003854^molecular_function^3-beta-hydroxy-delta5-steroid dehydrogenase activity,.,NA,NA,NA,NA,KEGG:bta:616694`KO:K07748,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN111348_c0_g1_i1,DN111348_c0_g1,PHS2_CHICK,Pterin-4-alpha-carbinolamine dehydratase 2,.,NA,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0006729^biological_process^tetrahydrobiopterin biosynthetic process,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:374030`KO:K01724,.,.,NA,NA,NA,NA,,
no,AD,DRA,DN125979_c1_g1_i1,DN125979_c1_g1,DRAM1_XENTR,DNA damage-regulated autophagy modulator protein 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005764^cellular_component^lysosome,GO:0006915^biological_process^apoptotic process,GO:0006914^biological_process^autophagy,.,NA,NA,NA,NA,KEGG:xtr:548586`KO:K21956,ENOG4111KNB^DNA-damage regulated autophagy modulator,.,NA,NA,NA,NA,,
no,AD,DRA,DN110532_c0_g1_i2,DN110532_c0_g1,FCER2_MOUSE,Low affinity immunoglobulin epsilon Fc receptor,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,GO:0019863^molecular_function^IgE binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:14128`KO:K06468,ENOG410XZ77^carbohydrate binding,.,NA,NA,NA,NA,,
no,AD,DRA,DN110532_c0_g1_i3,DN110532_c0_g1,FCER2_MOUSE,Low affinity immunoglobulin epsilon Fc receptor,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,GO:0019863^molecular_function^IgE binding,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:14128`KO:K06468,ENOG410XZ77^carbohydrate binding,.,NA,NA,NA,NA,,
no,AD,DRA,DN150146_c0_g1_i1,DN150146_c0_g1,AUHM_HUMAN,"Methylglutaconyl-CoA hydratase, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0050011^molecular_function^itaconyl-CoA hydratase activity,GO:0004490^molecular_function^methylglutaconyl-CoA hydratase activity,.,NA,NA,NA,NA,KEGG:hsa:549`KO:K05607,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN135073_c0_g1_i1,DN135073_c0_g1,ECHA_RAT,"Trifunctional enzyme subunit alpha, mitochondrial",.,NA,GO:0016507^cellular_component^mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0042645^cellular_component^mitochondrial nucleoid,GO:0005739^cellular_component^mitochondrion,GO:0003857^molecular_function^3-hydroxyacyl-CoA dehydrogenase activity,.,NA,NA,NA,NA,KEGG:rno:170670`KO:K07515,COG1024^Enoyl-CoA hydratase`COG1250^Dehydrogenase,.,NA,NA,NA,NA,,
no,AD,DRA,DN170548_c0_g1_i1,DN170548_c0_g1,PYGM_HUMAN,"Glycogen phosphorylase, muscle form",PYGM_HUMAN,"Glycogen phosphorylase, muscle form",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0008184^molecular_function^glycogen phosphorylase activity,GO:0102250^molecular_function^linear malto-oligosaccharide phosphorylase activity,KEGG:hsa:5837`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",PF00343.20^Phosphorylase^Carbohydrate phosphorylase^2-157^E:1.3e-70,NA,NA,NA,NA,,
no,AD,DRA,DN132664_c0_g1_i1,DN132664_c0_g1,PYGL_HUMAN,"Glycogen phosphorylase, liver form",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1904813^cellular_component^ficolin-1-rich granule lumen,.,NA,NA,NA,NA,KEGG:hsa:5836`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN200995_c0_g1_i1,DN200995_c0_g1,CDYL_MOUSE,Chromodomain Y-like protein {ECO:0000303|PubMed:10192397},.,NA,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,.,NA,NA,NA,NA,KEGG:mmu:12593`KO:K00653,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN211995_c0_g1_i1,DN211995_c0_g1,CAH14_HUMAN,Carbonic anhydrase 14,CAH14_HUMAN,Carbonic anhydrase 14,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,KEGG:hsa:23632`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^1-67^E:8.9e-18,NA,NA,NA,NA,,
no,AD,DRA,DN211995_c0_g2_i1,DN211995_c0_g2,CAH14_MOUSE,Carbonic anhydrase 14,CAH14_MOUSE,Carbonic anhydrase 14,GO:0016021^cellular_component^integral component of membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015670^biological_process^carbon dioxide transport,GO:0006885^biological_process^regulation of pH,GO:0016021^cellular_component^integral component of membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015670^biological_process^carbon dioxide transport,GO:0006885^biological_process^regulation of pH,KEGG:mmu:23831`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^7-120^E:2.5e-31,NA,NA,NA,NA,,
no,AD,DRA,DN230618_c0_g1_i2,DN230618_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN230618_c0_g1_i1,DN230618_c0_g1,ACOC_CHICK,Cytoplasmic aconitate hydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,"GO:0051538^molecular_function^3 iron, 4 sulfur cluster binding","GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003994^molecular_function^aconitate hydratase activity,.,NA,NA,NA,NA,KEGG:gga:373916`KO:K01681,COG1048^aconitate hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN233374_c0_g1_i1,DN233374_c0_g1,UXS1_DANRE,UDP-glucuronic acid decarboxylase 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0070403^molecular_function^NAD+ binding,GO:0048040^molecular_function^UDP-glucuronate decarboxylase activity,.,NA,NA,NA,NA,KEGG:dre:192315`KO:K08678,COG0451^Nad-dependent epimerase dehydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN235593_c0_g1_i1,DN235593_c0_g1,GMDS_MOUSE,"GDP-mannose 4,6 dehydratase",.,NA,GO:0005737^cellular_component^cytoplasm,"GO:0008446^molecular_function^GDP-mannose 4,6-dehydratase activity",GO:0042802^molecular_function^identical protein binding,GO:0070401^molecular_function^NADP+ binding,GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,.,NA,NA,NA,NA,KEGG:mmu:218138`KO:K01711,"COG1089^GDP-mannose 4,6-dehydratase",.,NA,NA,NA,NA,,
no,AD,DRA,DN234132_c0_g1_i1,DN234132_c0_g1,CQ10B_PONAB,"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial",.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172009`KO:K18588,COG2867^Cyclase dehydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN215602_c0_g1_i1,DN215602_c0_g1,HUTU_MOUSE,Urocanate hydratase,HUTU_HUMAN,Urocanate hydratase,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,GO:0005829^cellular_component^cytosol,GO:0016153^molecular_function^urocanate hydratase activity,GO:0006548^biological_process^histidine catabolic process,GO:0019556^biological_process^histidine catabolic process to glutamate and formamide,GO:0019557^biological_process^histidine catabolic process to glutamate and formate,KEGG:hsa:131669`KO:K01712,COG2987^Urocanate hydratase,PF17391.2^Urocanase_N^Urocanase N-terminal domain^1-90^E:3.8e-43,PF01175.18^Urocanase^Urocanase Rossmann-like domain^93-153^E:6e-26,NA,NA,NA,,
no,AD,DRA,DN267381_c0_g1_i1,DN267381_c0_g1,CAH3_PIG,Carbonic anhydrase 3,.,NA,GO:0005829^cellular_component^cytosol,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0016151^molecular_function^nickel cation binding,GO:0008270^molecular_function^zinc ion binding,GO:0009617^biological_process^response to bacterium,.,NA,NA,NA,NA,KEGG:ssc:494016`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN251428_c0_g1_i1,DN251428_c0_g1,PYGB_HUMAN,"Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}",.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5834`KO:K00688,"COG0058^Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)",.,NA,NA,NA,NA,,
no,AD,DRA,DN265383_c0_g1_i1,DN265383_c0_g1,ENOG_CHICK,Gamma-enolase,.,NA,GO:0005829^cellular_component^cytosol,GO:0000015^cellular_component^phosphopyruvate hydratase complex,GO:0000287^molecular_function^magnesium ion binding,GO:0004634^molecular_function^phosphopyruvate hydratase activity,GO:0006094^biological_process^gluconeogenesis,.,NA,NA,NA,NA,KEGG:gga:395689`KO:K01689,COG0148^Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity),.,NA,NA,NA,NA,,
no,AD,DRA,DN224508_c0_g1_i1,DN224508_c0_g1,CAH10_PONAB,Carbonic anhydrase-related protein 10,CAH10_PONAB,Carbonic anhydrase-related protein 10,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,NA,NA,.,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^45-300^E:3.9e-66,NA,NA,NA,NA,,
no,AD,DRA,DN257891_c0_g1_i1,DN257891_c0_g1,PTPRG_CHICK,Receptor-type tyrosine-protein phosphatase gamma,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004725^molecular_function^protein tyrosine phosphatase activity,GO:0006470^biological_process^protein dephosphorylation,NA,NA,.,NA,NA,NA,NA,.,COG3338^Carbonic anhydrase`COG5599^protein tyrosine phosphatase,.,NA,NA,NA,NA,,
no,AD,DRA,DN263819_c0_g1_i1,DN263819_c0_g1,CAH12_RABIT,Carbonic anhydrase 12,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,NA,NA,.,NA,NA,NA,NA,KEGG:ocu:100008777`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN346102_c0_g1_i1,DN346102_c0_g1,CAH12_HUMAN,Carbonic anhydrase 12,CAH12_HUMAN,Carbonic anhydrase 12,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015701^biological_process^bicarbonate transport,KEGG:hsa:771`KO:K01672,COG3338^Carbonic anhydrase,PF00194.21^Carb_anhydrase^Eukaryotic-type carbonic anhydrase^1-176^E:4.7e-60,NA,NA,NA,NA,,
no,AD,DRA,DN399776_c0_g1_i1,DN399776_c0_g1,CDYL_RAT,Chromodomain Y-like protein {ECO:0000250|UniProtKB:Q9Y232},.,NA,GO:0005694^cellular_component^chromosome,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,GO:0120092^molecular_function^crotonyl-CoA hydratase activity,.,NA,NA,NA,NA,KEGG:rno:361237`KO:K00653,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN309315_c0_g1_i1,DN309315_c0_g1,GMDS_HUMAN,"GDP-mannose 4,6 dehydratase",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,"GO:0008446^molecular_function^GDP-mannose 4,6-dehydratase activity",GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:hsa:2762`KO:K01711,"COG1089^GDP-mannose 4,6-dehydratase",.,NA,NA,NA,NA,,
no,AD,DRA,DN372047_c0_g1_i1,DN372047_c0_g1,CAH12_MOUSE,Carbonic anhydrase 12,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004089^molecular_function^carbonate dehydratase activity,GO:0008270^molecular_function^zinc ion binding,GO:0015670^biological_process^carbon dioxide transport,GO:0055064^biological_process^chloride ion homeostasis,.,NA,NA,NA,NA,KEGG:mmu:76459`KO:K01672,COG3338^Carbonic anhydrase,.,NA,NA,NA,NA,,
no,AD,DRA,DN393515_c0_g1_i1,DN393515_c0_g1,BTD_BOVIN,Biotinidase,.,NA,GO:0005615^cellular_component^extracellular space,GO:0047708^molecular_function^biotinidase activity,GO:0006768^biological_process^biotin metabolic process,NA,NA,.,NA,NA,NA,NA,KEGG:bta:537669`KO:K01435,COG0388^nitrilase cyanide hydratase and apolipoprotein n-acyltransferase,.,NA,NA,NA,NA,,
no,AD,DRA,DN370892_c0_g1_i1,DN370892_c0_g1,ECI1_HUMAN,"Enoyl-CoA delta isomerase 1, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004165^molecular_function^dodecenoyl-CoA delta-isomerase activity,GO:0004300^molecular_function^enoyl-CoA hydratase activity,GO:0006635^biological_process^fatty acid beta-oxidation,.,NA,NA,NA,NA,KEGG:hsa:1632`KO:K13238,COG1024^Enoyl-CoA hydratase,.,NA,NA,NA,NA,,
no,AD,DRA,DN430633_c0_g1_i1,DN430633_c0_g1,PHS_MOUSE,Pterin-4-alpha-carbinolamine dehydratase,.,NA,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008124^molecular_function^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:13180`KO:K01724,COG2154^4-alpha-hydroxytetrahydrobiopterin dehydratase activity,.,NA,NA,NA,NA,,
no,AD,DRA,DN401599_c0_g1_i1,DN401599_c0_g1,GMDS_CRIGR,"GDP-mannose 4,6 dehydratase",.,NA,"GO:0008446^molecular_function^GDP-mannose 4,6-dehydratase activity",GO:0042802^molecular_function^identical protein binding,GO:0070401^molecular_function^NADP+ binding,GO:0042351^biological_process^'de novo' GDP-L-fucose biosynthetic process,GO:0019673^biological_process^GDP-mannose metabolic process,.,NA,NA,NA,NA,KEGG:cge:100689436`KO:K01711,.,.,NA,NA,NA,NA,,
yes,AD,EFNA,DN3819_c0_g1_i4,DN3819_c0_g1,EFNA3_MOUSE,Ephrin-A3,EFNA3_MOUSE,Ephrin-A3,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,KEGG:mmu:13638`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^51-161^E:5.5e-39,NA,NA,NA,NA,,
yes,AD,EFNA,DN3819_c0_g1_i5,DN3819_c0_g1,EFNA3_MOUSE,Ephrin-A3,EFNA3_MOUSE,Ephrin-A3,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,KEGG:mmu:13638`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^51-176^E:9e-42,NA,NA,NA,NA,,
yes,AD,EFNA,DN3819_c0_g1_i1,DN3819_c0_g1,EFNA3_MOUSE,Ephrin-A3,EFNA3_MOUSE,Ephrin-A3,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,KEGG:mmu:13638`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN3819_c0_g1_i3,DN3819_c0_g1,EFNA3_MOUSE,Ephrin-A3,EFNA3_MOUSE,Ephrin-A3,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0048013^biological_process^ephrin receptor signaling pathway,KEGG:mmu:13638`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^51-161^E:4.6e-39,NA,NA,NA,NA,,
yes,AD,EFNA,DN12600_c0_g1_i3,DN12600_c0_g1,EFNA2_CHICK,Ephrin-A2,EFNA2_CHICK,Ephrin-A2,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,KEGG:gga:395831`KO:K05462,.,PF00812.17^Ephrin^Ephrin^26-153^E:6e-42,NA,NA,NA,NA,,
yes,AD,EFNA,DN12600_c0_g1_i1,DN12600_c0_g1,EFNA2_CHICK,Ephrin-A2,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,.,NA,NA,NA,NA,KEGG:gga:395831`KO:K05462,.,.,NA,NA,NA,NA,,
yes,AD,EFNA,DN12600_c0_g1_i2,DN12600_c0_g1,EFNA2_CHICK,Ephrin-A2,EFNA2_CHICK,Ephrin-A2,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,KEGG:gga:395831`KO:K05462,.,PF00812.17^Ephrin^Ephrin^51-178^E:8.5e-42,NA,NA,NA,NA,,
yes,AD,EFNA,DN1434_c0_g1_i7,DN1434_c0_g1,EFNA1_PIG,Ephrin-A1,EFNA1_PIG,Ephrin-A1,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,KEGG:ssc:100144501`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^33-161^E:1.6e-43,NA,NA,NA,NA,,
yes,AD,EFNA,DN1434_c0_g1_i11,DN1434_c0_g1,EFNA1_PIG,Ephrin-A1,EFNA1_PIG,Ephrin-A1,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,KEGG:ssc:100144501`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^2-116^E:1e-35,NA,NA,NA,NA,,
yes,AD,EFNA,DN1434_c0_g1_i9,DN1434_c0_g1,EFNA1_PIG,Ephrin-A1,.,NA,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,.,NA,NA,NA,NA,KEGG:ssc:100144501`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN1434_c0_g1_i1,DN1434_c0_g1,EFNA1_PIG,Ephrin-A1,.,NA,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,.,NA,NA,NA,NA,KEGG:ssc:100144501`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN1434_c0_g1_i5,DN1434_c0_g1,EFNA1_PIG,Ephrin-A1,EFNA1_PIG,Ephrin-A1,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,GO:0046658^cellular_component^anchored component of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0001525^biological_process^angiogenesis,KEGG:ssc:100144501`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^1-84^E:9.2e-23,NA,NA,NA,NA,,
yes,AD,EFNA,DN28471_c0_g1_i4,DN28471_c0_g1,EFNA4_MOUSE,Ephrin-A4,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,.,NA,NA,NA,NA,KEGG:mmu:13639`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN28471_c0_g1_i2,DN28471_c0_g1,EFNA4_MOUSE,Ephrin-A4,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,.,NA,NA,NA,NA,KEGG:mmu:13639`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN28471_c0_g1_i6,DN28471_c0_g1,EFNA4_MOUSE,Ephrin-A4,EFNA4_MOUSE,Ephrin-A4,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,KEGG:mmu:13639`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^37-163^E:5.4e-39,NA,NA,NA,NA,,
yes,AD,EFNA,DN28471_c0_g1_i5,DN28471_c0_g1,EFNA4_MOUSE,Ephrin-A4,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,.,NA,NA,NA,NA,KEGG:mmu:13639`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN28471_c0_g1_i11,DN28471_c0_g1,EFNA4_MOUSE,Ephrin-A4,EFNA4_MOUSE,Ephrin-A4,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,GO:0031225^cellular_component^anchored component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0046849^biological_process^bone remodeling,KEGG:mmu:13639`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^1-77^E:6.4e-18,NA,NA,NA,NA,,
yes,AD,EFNA,DN110263_c0_g1_i3,DN110263_c0_g1,EFNA5_HUMAN,Ephrin-A5,.,NA,GO:0005912^cellular_component^adherens junction,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0005604^cellular_component^basement membrane,GO:0005901^cellular_component^caveola,GO:0098982^cellular_component^GABA-ergic synapse,.,NA,NA,NA,NA,KEGG:hsa:1946`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN110263_c0_g1_i2,DN110263_c0_g1,EFNA5_HUMAN,Ephrin-A5,.,NA,GO:0005912^cellular_component^adherens junction,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0005604^cellular_component^basement membrane,GO:0005901^cellular_component^caveola,GO:0098982^cellular_component^GABA-ergic synapse,.,NA,NA,NA,NA,KEGG:hsa:1946`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN110263_c0_g1_i4,DN110263_c0_g1,EFNA5_HUMAN,Ephrin-A5,.,NA,GO:0005912^cellular_component^adherens junction,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0005604^cellular_component^basement membrane,GO:0005901^cellular_component^caveola,GO:0098982^cellular_component^GABA-ergic synapse,.,NA,NA,NA,NA,KEGG:hsa:1946`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",.,NA,NA,NA,NA,,
yes,AD,EFNA,DN110263_c0_g1_i1,DN110263_c0_g1,EFNA5_CHICK,Ephrin-A5,EFNA5_CHICK,Ephrin-A5,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,GO:0046875^molecular_function^ephrin receptor binding,GO:0007411^biological_process^axon guidance,KEGG:gga:396100`KO:K05462,"ENOG4111FMJ^ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells",PF00812.17^Ephrin^Ephrin^30-157^E:4.3e-40,NA,NA,NA,NA,,
no,AD,EGF,DN4707_c0_g1_i5,DN4707_c0_g1,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:gga:395654`KO:K08523,ENOG41120D3^heparin-binding EGF-like growth factor,PF00008.27^EGF^EGF-like domain^130-160^E:3.6e-05,NA,NA,NA,NA,,
no,AD,EGF,DN4707_c0_g1_i4,DN4707_c0_g1,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:gga:395654`KO:K08523,ENOG41120D3^heparin-binding EGF-like growth factor,.,NA,NA,NA,NA,,
no,AD,EGF,DN4707_c0_g1_i2,DN4707_c0_g1,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:gga:395654`KO:K08523,ENOG41120D3^heparin-binding EGF-like growth factor,.,NA,NA,NA,NA,,
no,AD,EGF,DN4707_c0_g1_i1,DN4707_c0_g1,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:gga:395654`KO:K08523,ENOG41120D3^heparin-binding EGF-like growth factor,.,NA,NA,NA,NA,,
no,AD,EGF,DN4707_c0_g1_i3,DN4707_c0_g1,HBEGF_CHICK,Proheparin-binding EGF-like growth factor,.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005154^molecular_function^epidermal growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:gga:395654`KO:K08523,ENOG41120D3^heparin-binding EGF-like growth factor,.,NA,NA,NA,NA,,
yes,AD,EGF,DN3813_c0_g1_i3,DN3813_c0_g1,EGFR_MOUSE,Epidermal growth factor receptor,EGFR_MOUSE,Epidermal growth factor receptor,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,KEGG:mmu:13649`KO:K04361,ENOG410XNSR^erythroblastic leukemia viral oncogene homolog,PF01030.24^Recep_L_domain^Receptor L domain^151-262^E:1.9e-29,PF00757.20^Furin-like^Furin-like cysteine rich region^281-433^E:5.3e-30,PF01030.24^Recep_L_domain^Receptor L domain^456-575^E:6.4e-27,PF14843.6^GF_recep_IV^Growth factor receptor domain IV^600-734^E:2.1e-47,PF00069.25^Pkinase^Protein kinase domain^809-1062^E:1.3e-39,,
yes,AD,EGF,DN3813_c0_g1_i6,DN3813_c0_g1,EGFR_MOUSE,Epidermal growth factor receptor,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,.,NA,NA,NA,NA,KEGG:mmu:13649`KO:K04361,ENOG410XNSR^erythroblastic leukemia viral oncogene homolog,.,NA,NA,NA,NA,,
yes,AD,EGF,DN3813_c0_g1_i10,DN3813_c0_g1,EGFR_MOUSE,Epidermal growth factor receptor,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009925^cellular_component^basal plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,.,NA,NA,NA,NA,KEGG:mmu:13649`KO:K04361,ENOG410XNSR^erythroblastic leukemia viral oncogene homolog,.,NA,NA,NA,NA,,
no,AD,EGF,DN2943_c7_g1_i1,DN2943_c7_g1,EGFLA_BOVIN,Pikachurin,EGFLA_BOVIN,Pikachurin,GO:0005604^cellular_component^basement membrane,GO:0030054^cellular_component^cell junction,GO:0045202^cellular_component^synapse,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0005604^cellular_component^basement membrane,GO:0030054^cellular_component^cell junction,GO:0045202^cellular_component^synapse,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,KEGG:bta:534427,ENOG410XTD2^heparan sulfate proteoglycan,PF00041.21^fn3^Fibronectin type III domain^162-246^E:9.3e-14,PF00054.23^Laminin_G_1^Laminin G domain^439-570^E:4.9e-26,PF02210.24^Laminin_G_2^Laminin G domain^439-567^E:4.4e-21,PF12661.7^hEGF^Human growth factor-like EGF^598-620^E:0.0013,PF00054.23^Laminin_G_1^Laminin G domain^665-793^E:1.1e-25,,
Yes,,EGF,DN44225_c0_g1_i1,DN44225_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,VWCE_MOUSE,von Willebrand factor C and EGF domain-containing protein,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,KEGG:mmu:71768,ENOG4110VWF^von Willebrand factor C and EGF domains,.,NA,NA,NA,NA,,
Yes,,EGF,DN44225_c0_g1_i5,DN44225_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,KEGG:hsa:220001,ENOG4110VWF^von Willebrand factor C and EGF domains,PF07645.15^EGF_CA^Calcium-binding EGF domain^165-202^E:1.6e-06,NA,NA,NA,NA,,
Yes,,EGF,DN44225_c0_g1_i4,DN44225_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,.,NA,NA,NA,NA,KEGG:hsa:220001,ENOG4110VWF^von Willebrand factor C and EGF domains,.,NA,NA,NA,NA,,
Yes,,EGF,DN44225_c0_g1_i3,DN44225_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,.,NA,NA,NA,NA,KEGG:hsa:220001,ENOG4110VWF^von Willebrand factor C and EGF domains,.,NA,NA,NA,NA,,
Yes,,EGF,DN44225_c0_g1_i2,DN44225_c0_g1,VWCE_MOUSE,von Willebrand factor C and EGF domain-containing protein,VWCE_MOUSE,von Willebrand factor C and EGF domain-containing protein,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,KEGG:mmu:71768,ENOG4110VWF^von Willebrand factor C and EGF domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN42630_c0_g1_i1,DN42630_c0_g1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00028.17^Cadherin^Cadherin domain^34-122^E:5.9e-18,PF00028.17^Cadherin^Cadherin domain^136-224^E:7.2e-24,PF00028.17^Cadherin^Cadherin domain^239-331^E:3.3e-19,PF00028.17^Cadherin^Cadherin domain^347-432^E:1.5e-18,NA,,
no,AD,EGF,DN894_c0_g1_i5,DN894_c0_g1,SREC2_HUMAN,Scavenger receptor class F member 2,SREC2_HUMAN,Scavenger receptor class F member 2,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,KEGG:hsa:91179,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^49-77^E:0.006,PF00053.24^Laminin_EGF^Laminin EGF domain^138-165^E:0.031,NA,NA,NA,,
no,AD,EGF,DN894_c0_g1_i13,DN894_c0_g1,SREC2_HUMAN,Scavenger receptor class F member 2,SREC2_HUMAN,Scavenger receptor class F member 2,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,KEGG:hsa:91179,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN894_c0_g1_i6,DN894_c0_g1,SREC2_HUMAN,Scavenger receptor class F member 2,.,NA,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:91179,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN894_c0_g1_i8,DN894_c0_g1,SREC2_HUMAN,Scavenger receptor class F member 2,SREC2_HUMAN,Scavenger receptor class F member 2,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,KEGG:hsa:91179,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^49-77^E:0.006,PF00053.24^Laminin_EGF^Laminin EGF domain^138-165^E:0.031,NA,NA,NA,,
no,AD,EGF,DN894_c0_g1_i7,DN894_c0_g1,SREC2_HUMAN,Scavenger receptor class F member 2,.,NA,GO:0005925^cellular_component^focal adhesion,GO:0016021^cellular_component^integral component of membrane,GO:0007157^biological_process^heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:91179,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN40978_c0_g1_i1,DN40978_c0_g1,TEFF2_HUMAN,Tomoregulin-2,TEFF2_HUMAN,Tomoregulin-2,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0030336^biological_process^negative regulation of cell migration,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0030336^biological_process^negative regulation of cell migration,KEGG:hsa:23671,ENOG4110TEU^transmembrane protein with EGF-like and two follistatin-like domains 2,PF07648.15^Kazal_2^Kazal-type serine protease inhibitor domain^95-139^E:1.6e-10,PF00050.21^Kazal_1^Kazal-type serine protease inhibitor domain^98-139^E:7.3e-09,PF07648.15^Kazal_2^Kazal-type serine protease inhibitor domain^186-231^E:2.7e-09,PF00050.21^Kazal_1^Kazal-type serine protease inhibitor domain^189-231^E:4.7e-06,NA,,
no,AD,EGF,DN38251_c0_g1_i3,DN38251_c0_g1,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,KEGG:hsa:84465,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^53-94^E:0.0086,PF12661.7^hEGF^Human growth factor-like EGF^55-74^E:0.0025,PF00053.24^Laminin_EGF^Laminin EGF domain^141-177^E:0.0034,PF00053.24^Laminin_EGF^Laminin EGF domain^227-264^E:0.0013,PF00053.24^Laminin_EGF^Laminin EGF domain^270-298^E:0.00033,,
no,AD,EGF,DN38251_c0_g1_i1,DN38251_c0_g1,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,KEGG:hsa:84465,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN38251_c0_g1_i5,DN38251_c0_g1,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,MEG11_HUMAN,Multiple epidermal growth factor-like domains protein 11,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0034109^biological_process^homotypic cell-cell adhesion,GO:0010842^biological_process^retina layer formation,NA,KEGG:hsa:84465,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^53-94^E:0.0081,PF12661.7^hEGF^Human growth factor-like EGF^55-74^E:0.0024,PF00053.24^Laminin_EGF^Laminin EGF domain^141-177^E:0.0032,PF00053.24^Laminin_EGF^Laminin EGF domain^227-264^E:0.00021,PF00053.24^Laminin_EGF^Laminin EGF domain^270-298^E:0.00032,,
no,AD,EGF,DN53844_c1_g1_i2,DN53844_c1_g1,MEG10_HUMAN,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634},MEG10_MOUSE,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|MGI:MGI:2685177},GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,KEGG:mmu:70417,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^22-50^E:0.0008,NA,NA,NA,NA,,
no,AD,EGF,DN53844_c1_g1_i1,DN53844_c1_g1,MEG10_HUMAN,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634},MEG10_HUMAN,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634},GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,KEGG:hsa:84466,ENOG410XQWV^multiple EGF-like-domains,PF12661.7^hEGF^Human growth factor-like EGF^111-128^E:0.049,PF00053.24^Laminin_EGF^Laminin EGF domain^150-193^E:0.047,PF12661.7^hEGF^Human growth factor-like EGF^195-214^E:8.6e-06,PF12661.7^hEGF^Human growth factor-like EGF^238-257^E:0.0013,PF00053.24^Laminin_EGF^Laminin EGF domain^279-322^E:0.00065,,
no,AD,EGF,DN53844_c1_g1_i3,DN53844_c1_g1,MEG10_HUMAN,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634},MEG10_HUMAN,Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634},GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,GO:0042995^cellular_component^cell projection,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0001849^molecular_function^complement component C1q binding,KEGG:hsa:84466,ENOG410XQWV^multiple EGF-like-domains,PF12661.7^hEGF^Human growth factor-like EGF^195-214^E:6.5e-05,PF12661.7^hEGF^Human growth factor-like EGF^238-257^E:0.0024,PF00053.24^Laminin_EGF^Laminin EGF domain^279-322^E:0.0013,PF12661.7^hEGF^Human growth factor-like EGF^281-300^E:0.0071,PF00053.24^Laminin_EGF^Laminin EGF domain^322-366^E:0.015,,
no,AD,EGF,DN26806_c0_g1_i2,DN26806_c0_g1,SREC_HUMAN,Scavenger receptor class F member 1,SREC_HUMAN,Scavenger receptor class F member 1,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030169^molecular_function^low-density lipoprotein particle binding,GO:0005044^molecular_function^scavenger receptor activity,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030169^molecular_function^low-density lipoprotein particle binding,GO:0005044^molecular_function^scavenger receptor activity,KEGG:hsa:8578,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN43090_c0_g1_i1,DN43090_c0_g1,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,.,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN2753_c0_g3_i1,DN2753_c0_g3,SREC_HUMAN,Scavenger receptor class F member 1,SREC_HUMAN,Scavenger receptor class F member 1,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030169^molecular_function^low-density lipoprotein particle binding,GO:0005044^molecular_function^scavenger receptor activity,GO:0030666^cellular_component^endocytic vesicle membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030169^molecular_function^low-density lipoprotein particle binding,GO:0005044^molecular_function^scavenger receptor activity,KEGG:hsa:8578,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN84884_c0_g1_i1,DN84884_c0_g1,TEFF2_HUMAN,Tomoregulin-2,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0030336^biological_process^negative regulation of cell migration,.,NA,NA,NA,NA,KEGG:hsa:23671,ENOG4110TEU^transmembrane protein with EGF-like and two follistatin-like domains 2,.,NA,NA,NA,NA,,
no,AD,EGF,DN15057_c0_g2_i7,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",.,NA,NA,NA,NA,,
no,AD,EGF,DN15057_c0_g2_i20,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:1e-09,PF12947.7^EGF_3^EGF domain^62-97^E:5.2e-10,PF00008.27^EGF^EGF-like domain^62-93^E:1.9e-05,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:0.00047,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:1.3e-07,,
no,AD,EGF,DN15057_c0_g2_i15,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",.,NA,NA,NA,NA,,
no,AD,EGF,DN15057_c0_g2_i5,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^63-110^E:4.9e-14,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^117-164^E:3.6e-13,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^173-220^E:1.2e-15,PF00431.20^CUB^CUB domain^225-334^E:8.8e-18,NA,,
no,AD,EGF,DN15057_c0_g2_i13,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^83-118^E:6.9e-12,PF12662.7^cEGF^Complement Clr-like EGF-like^102-123^E:1.6e-09,PF07645.15^EGF_CA^Calcium-binding EGF domain^120-159^E:2.2e-07,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^124-159^E:1e-12,PF12662.7^cEGF^Complement Clr-like EGF-like^141-164^E:1.3e-08,,
no,AD,EGF,DN15057_c0_g2_i12,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^81-128^E:6.1e-14,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^135-182^E:4.4e-13,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^191-238^E:1.5e-15,PF00431.20^CUB^CUB domain^243-352^E:1.2e-17,NA,,
no,AD,EGF,DN15057_c0_g2_i17,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:3.5e-10,PF12947.7^EGF_3^EGF domain^62-97^E:1.8e-10,PF00008.27^EGF^EGF-like domain^62-93^E:6.8e-06,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:0.00017,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:4.6e-08,,
no,AD,EGF,DN15057_c0_g2_i21,DN15057_c0_g2,SCUB1_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:64706,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:5.7e-10,PF12947.7^EGF_3^EGF domain^62-97^E:2.8e-10,PF00008.27^EGF^EGF-like domain^62-93^E:1.1e-05,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:0.00027,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:7.2e-08,,
no,AD,EGF,DN15057_c0_g2_i8,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",.,NA,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",.,NA,NA,NA,NA,,
no,AD,EGF,DN15057_c0_g2_i10,DN15057_c0_g2,SCUB1_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:64706,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:1.1e-09,PF12947.7^EGF_3^EGF domain^62-97^E:5.3e-10,PF00008.27^EGF^EGF-like domain^62-93^E:2e-05,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:0.00048,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:1.3e-07,,
no,AD,EGF,DN15057_c0_g2_i3,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^3-38^E:7e-13,PF12662.7^cEGF^Complement Clr-like EGF-like^22-43^E:2e-10,PF07645.15^EGF_CA^Calcium-binding EGF domain^40-79^E:2.1e-08,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^44-79^E:1e-13,PF12662.7^cEGF^Complement Clr-like EGF-like^61-84^E:1.6e-09,,
no,AD,EGF,DN15057_c0_g2_i16,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^83-118^E:6.9e-12,PF12662.7^cEGF^Complement Clr-like EGF-like^102-123^E:1.6e-09,PF07645.15^EGF_CA^Calcium-binding EGF domain^120-159^E:2.2e-07,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^124-159^E:1e-12,PF12662.7^cEGF^Complement Clr-like EGF-like^141-164^E:1.3e-08,,
no,AD,EGF,DN15057_c0_g2_i6,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^63-110^E:7.8e-15,NA,NA,NA,NA,,
no,AD,EGF,DN15057_c0_g2_i9,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:1.5e-10,PF12947.7^EGF_3^EGF domain^62-97^E:7.6e-11,PF00008.27^EGF^EGF-like domain^62-93^E:3e-06,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:7.9e-05,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:2.2e-08,,
no,AD,EGF,DN15057_c0_g2_i19,DN15057_c0_g2,SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",SCUB1_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 1",GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:80274,"ENOG411030G^Signal peptide, CUB domain, EGF-like",PF07645.15^EGF_CA^Calcium-binding EGF domain^58-97^E:1.5e-10,PF12947.7^EGF_3^EGF domain^62-97^E:7.9e-11,PF00008.27^EGF^EGF-like domain^62-93^E:3.1e-06,PF12661.7^hEGF^Human growth factor-like EGF^69-90^E:8.2e-05,PF12662.7^cEGF^Complement Clr-like EGF-like^81-102^E:2.2e-08,,
no,AD,EGF,DN6792_c0_g1_i8,DN6792_c0_g1,ALDOC_CHICK,Fructose-bisphosphate aldolase C,EGFL7_RAT,Epidermal growth factor-like protein 7,GO:0005829^cellular_component^cytosol,GO:0004332^molecular_function^fructose-bisphosphate aldolase activity,"GO:0030388^biological_process^fructose 1,6-bisphosphate metabolic process",GO:0006094^biological_process^gluconeogenesis,GO:0006096^biological_process^glycolytic process,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005102^molecular_function^signaling receptor binding,KEGG:rno:245963,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07546.13^EMI^EMI domain^46-80^E:3e-07,NA,NA,NA,NA,,
no,AD,EGF,DN6792_c0_g1_i6,DN6792_c0_g1,ALDOC_CHICK,Fructose-bisphosphate aldolase C,EGFL7_RAT,Epidermal growth factor-like protein 7,GO:0005829^cellular_component^cytosol,GO:0004332^molecular_function^fructose-bisphosphate aldolase activity,"GO:0030388^biological_process^fructose 1,6-bisphosphate metabolic process",GO:0006094^biological_process^gluconeogenesis,GO:0006096^biological_process^glycolytic process,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005102^molecular_function^signaling receptor binding,KEGG:rno:245963,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07546.13^EMI^EMI domain^53-87^E:3.5e-07,NA,NA,NA,NA,,
no,AD,EGF,DN6792_c0_g1_i10,DN6792_c0_g1,ALDOC_CHICK,Fructose-bisphosphate aldolase C,EGFL7_RAT,Epidermal growth factor-like protein 7,GO:0005829^cellular_component^cytosol,GO:0004332^molecular_function^fructose-bisphosphate aldolase activity,"GO:0030388^biological_process^fructose 1,6-bisphosphate metabolic process",GO:0006094^biological_process^gluconeogenesis,GO:0006096^biological_process^glycolytic process,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005102^molecular_function^signaling receptor binding,KEGG:rno:245963,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07546.13^EMI^EMI domain^45-79^E:3e-07,NA,NA,NA,NA,,
no,AD,EGF,DN237_c0_g1_i13,DN237_c0_g1,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN237_c0_g1_i5,DN237_c0_g1,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN237_c0_g1_i14,DN237_c0_g1,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN237_c0_g1_i12,DN237_c0_g1,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN237_c0_g1_i7,DN237_c0_g1,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",PF06119.14^NIDO^Nidogen-like^196-283^E:1.5e-26,PF00008.27^EGF^EGF-like domain^299-334^E:7e-06,PF12661.7^hEGF^Human growth factor-like EGF^305-330^E:0.077,PF07645.15^EGF_CA^Calcium-binding EGF domain^338-373^E:8e-07,PF00008.27^EGF^EGF-like domain^342-371^E:2e-08,,
no,AD,EGF,DN237_c0_g1_i8,DN237_c0_g1,SNED1_HUMAN,"Sushi, nidogen and EGF-like domain-containing protein 1",SNED1_HUMAN,"Sushi, nidogen and EGF-like domain-containing protein 1",GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,KEGG:hsa:25992,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",PF00041.21^fn3^Fibronectin type III domain^4-82^E:2.2e-09,PF00041.21^fn3^Fibronectin type III domain^103-183^E:5.1e-10,PF00041.21^fn3^Fibronectin type III domain^202-278^E:9.2e-14,PF00008.27^EGF^EGF-like domain^402-432^E:1.3e-09,PF12661.7^hEGF^Human growth factor-like EGF^407-428^E:3.6e-05,,
no,AD,EGF,DN237_c0_g1_i15,DN237_c0_g1,SNED1_HUMAN,"Sushi, nidogen and EGF-like domain-containing protein 1",SNED1_HUMAN,"Sushi, nidogen and EGF-like domain-containing protein 1",GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,KEGG:hsa:25992,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",PF00041.21^fn3^Fibronectin type III domain^4-82^E:2e-09,PF00041.21^fn3^Fibronectin type III domain^103-183^E:4.6e-10,PF00041.21^fn3^Fibronectin type III domain^202-278^E:8.3e-14,PF00008.27^EGF^EGF-like domain^402-432^E:1.2e-09,PF00053.24^Laminin_EGF^Laminin EGF domain^402-435^E:0.049,,
no,AD,EGF,DN237_c5_g1_i1,DN237_c5_g1,FBLN4_HUMAN,EGF-containing fibulin-like extracellular matrix protein 2,FBLN4_HUMAN,EGF-containing fibulin-like extracellular matrix protein 2,GO:0005604^cellular_component^basement membrane,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1903561^cellular_component^extracellular vesicle,GO:0005604^cellular_component^basement membrane,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1903561^cellular_component^extracellular vesicle,KEGG:hsa:30008`KO:K19866,ENOG410ZNNG^EGF containing fibulin-like extracellular matrix protein 2,PF07645.15^EGF_CA^Calcium-binding EGF domain^74-101^E:3.8e-06,NA,NA,NA,NA,,
no,AD,EGF,DN237_c5_g1_i2,DN237_c5_g1,FBLN4_HUMAN,EGF-containing fibulin-like extracellular matrix protein 2,FBLN3_RAT,EGF-containing fibulin-like extracellular matrix protein 1,GO:0005604^cellular_component^basement membrane,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:1903561^cellular_component^extracellular vesicle,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005154^molecular_function^epidermal growth factor receptor binding,KEGG:hsa:30008`KO:K19866,ENOG410YCRW^epidermal growth factor-activated receptor activity,PF07645.15^EGF_CA^Calcium-binding EGF domain^74-101^E:6.5e-06,NA,NA,NA,NA,,
no,AD,EGF,DN3186_c0_g1_i1,DN3186_c0_g1,CCBE1_HUMAN,Collagen and calcium-binding EGF domain-containing protein 1,CCBE1_HUMAN,Collagen and calcium-binding EGF domain-containing protein 1,GO:0005581^cellular_component^collagen trimer,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005518^molecular_function^collagen binding,GO:0005581^cellular_component^collagen trimer,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0005518^molecular_function^collagen binding,KEGG:hsa:147372`KO:K19638,ENOG4111SKA^Collagen and calcium binding EGF domains 1,PF07645.15^EGF_CA^Calcium-binding EGF domain^138-178^E:1.3e-09,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^142-178^E:4.2e-09,PF12661.7^hEGF^Human growth factor-like EGF^153-169^E:0.062,PF01391.18^Collagen^Collagen triple helix repeat (20 copies)^247-291^E:1e-07,NA,,
no,AD,EGF,DN3193_c0_g1_i14,DN3193_c0_g1,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,.,ENOG410YF0N^Multiple EGF-like-domains 8,PF00053.24^Laminin_EGF^Laminin EGF domain^116-140^E:0.0025,NA,NA,NA,NA,,
no,AD,EGF,DN36254_c0_g1_i1,DN36254_c0_g1,SNED1_RAT,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,.,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN18137_c0_g1_i2,DN18137_c0_g1,EDIL3_HUMAN,EGF-like repeat and discoidin I-like domain-containing protein 3,EDIL3_HUMAN,EGF-like repeat and discoidin I-like domain-containing protein 3,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:1903561^cellular_component^extracellular vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:1903561^cellular_component^extracellular vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,KEGG:hsa:10085,ENOG41114BV^Milk fat globule-EGF factor 8 protein,PF00008.27^EGF^EGF-like domain^46-77^E:9e-08,PF12661.7^hEGF^Human growth factor-like EGF^51-74^E:0.0003,PF00008.27^EGF^EGF-like domain^98-135^E:2.2e-07,PF00008.27^EGF^EGF-like domain^143-166^E:0.00018,PF12661.7^hEGF^Human growth factor-like EGF^148-166^E:0.00068,,
no,AD,EGF,DN18137_c0_g1_i1,DN18137_c0_g1,EDIL3_HUMAN,EGF-like repeat and discoidin I-like domain-containing protein 3,EDIL3_HUMAN,EGF-like repeat and discoidin I-like domain-containing protein 3,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:1903561^cellular_component^extracellular vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:1903561^cellular_component^extracellular vesicle,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,KEGG:hsa:10085,ENOG41114BV^Milk fat globule-EGF factor 8 protein,PF00008.27^EGF^EGF-like domain^46-77^E:8.8e-08,PF12661.7^hEGF^Human growth factor-like EGF^51-74^E:0.00029,PF00008.27^EGF^EGF-like domain^88-125^E:2.1e-07,PF00008.27^EGF^EGF-like domain^133-156^E:0.00018,PF12661.7^hEGF^Human growth factor-like EGF^138-156^E:0.00067,,
no,AD,EGF,DN94281_c0_g1_i1,DN94281_c0_g1,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,KEGG:hsa:1954,ENOG410YF0N^Multiple EGF-like-domains 8,PF01437.25^PSI^Plexin repeat^158-212^E:3.9e-05,PF01437.25^PSI^Plexin repeat^213-246^E:1.4e-05,NA,NA,NA,,
no,AD,EGF,DN94281_c0_g1_i3,DN94281_c0_g1,MEGF8_MOUSE,Multiple epidermal growth factor-like domains protein 8,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,KEGG:mmu:269878,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN92620_c0_g1_i2,DN92620_c0_g1,EGFLA_BOVIN,Pikachurin,.,NA,GO:0005604^cellular_component^basement membrane,GO:0030054^cellular_component^cell junction,GO:0045202^cellular_component^synapse,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,.,NA,NA,NA,NA,KEGG:bta:534427,ENOG410XTD2^heparan sulfate proteoglycan,.,NA,NA,NA,NA,,
no,AD,EGF,DN92620_c0_g1_i1,DN92620_c0_g1,EGFLA_BOVIN,Pikachurin,.,NA,GO:0005604^cellular_component^basement membrane,GO:0030054^cellular_component^cell junction,GO:0045202^cellular_component^synapse,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,.,NA,NA,NA,NA,KEGG:bta:534427,ENOG410XTD2^heparan sulfate proteoglycan,.,NA,NA,NA,NA,,
no,AD,EGF,DN15703_c0_g2_i4,DN15703_c0_g2,SNED1_MOUSE,"Sushi, nidogen and EGF-like domain-containing protein 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0005112^molecular_function^Notch binding,GO:0007160^biological_process^cell-matrix adhesion,NA,.,NA,NA,NA,NA,KEGG:mmu:208777,"ENOG410ZK2K^sushi, nidogen and EGF-like domains 1",.,NA,NA,NA,NA,,
no,AD,EGF,DN15792_c0_g1_i2,DN15792_c0_g1,MEGF6_MOUSE,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN15792_c0_g1_i3,DN15792_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN15792_c0_g1_i4,DN15792_c0_g1,MEGF6_MOUSE,Multiple epidermal growth factor-like domains protein 6,MEGF6_MOUSE,Multiple epidermal growth factor-like domains protein 6,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,ENOG410XQWV^multiple EGF-like-domains,PF12661.7^hEGF^Human growth factor-like EGF^16-35^E:0.00018,PF00053.24^Laminin_EGF^Laminin EGF domain^57-100^E:0.036,PF12661.7^hEGF^Human growth factor-like EGF^59-78^E:0.00075,PF12661.7^hEGF^Human growth factor-like EGF^102-121^E:0.016,PF12661.7^hEGF^Human growth factor-like EGF^145-163^E:0.074,,
no,AD,EGF,DN7433_c1_g2_i3,DN7433_c1_g2,TEFF1_HUMAN,Tomoregulin-1,CAVN4_XENLA,Caveolae-associated protein 4,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0009888^biological_process^tissue development,NA,GO:0005901^cellular_component^caveola,GO:0005886^cellular_component^plasma membrane,GO:0030017^cellular_component^sarcomere,GO:0030154^biological_process^cell differentiation,GO:0007517^biological_process^muscle organ development,KEGG:xla:100037205,ENOG410XQG4^transmembrane protein with EGF-like and two follistatin-like domains 1,PF15237.6^PTRF_SDPR^PTRF/SDPR family^28-254^E:4.6e-92,NA,NA,NA,NA,,
no,AD,EGF,DN6540_c0_g1_i4,DN6540_c0_g1,SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,KEGG:hsa:79987`KO:K17495,ENOG410XPJ1^c-type lectin domain family,PF00092.28^VWA^von Willebrand factor type A domain^70-241^E:8e-33,PF13519.6^VWA_2^von Willebrand factor type A domain^70-183^E:6.1e-12,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^296-346^E:5e-12,PF00084.20^Sushi^Sushi repeat (SCR repeat)^364-419^E:3.3e-06,PF00084.20^Sushi^Sushi repeat (SCR repeat)^424-479^E:1e-09,,
no,AD,EGF,DN6540_c0_g1_i9,DN6540_c0_g1,SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,KEGG:hsa:79987`KO:K17495,ENOG410XPJ1^c-type lectin domain family,PF00092.28^VWA^von Willebrand factor type A domain^70-241^E:8.6e-33,PF13519.6^VWA_2^von Willebrand factor type A domain^70-183^E:6.5e-12,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^296-346^E:5.3e-12,PF00084.20^Sushi^Sushi repeat (SCR repeat)^364-419^E:3.4e-06,PF00084.20^Sushi^Sushi repeat (SCR repeat)^424-479^E:1.1e-09,,
no,AD,EGF,DN6540_c0_g1_i11,DN6540_c0_g1,SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,KEGG:hsa:79987`KO:K17495,ENOG410XPJ1^c-type lectin domain family,PF00092.28^VWA^von Willebrand factor type A domain^70-241^E:8.7e-33,PF13519.6^VWA_2^von Willebrand factor type A domain^70-183^E:6.7e-12,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^296-346^E:5.4e-12,PF00084.20^Sushi^Sushi repeat (SCR repeat)^364-419^E:3.5e-06,PF00084.20^Sushi^Sushi repeat (SCR repeat)^424-479^E:1.1e-09,,
no,AD,EGF,DN6540_c0_g1_i12,DN6540_c0_g1,SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,KEGG:hsa:79987`KO:K17495,ENOG410XPJ1^c-type lectin domain family,PF00092.28^VWA^von Willebrand factor type A domain^70-241^E:8.4e-33,PF13519.6^VWA_2^von Willebrand factor type A domain^70-183^E:6.4e-12,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^296-346^E:5.2e-12,PF00084.20^Sushi^Sushi repeat (SCR repeat)^364-419^E:3.5e-06,PF00084.20^Sushi^Sushi repeat (SCR repeat)^424-479^E:1.1e-09,,
no,AD,EGF,DN6540_c0_g1_i5,DN6540_c0_g1,SVEP1_HUMAN,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:hsa:79987`KO:K17495,ENOG410XPJ1^c-type lectin domain family,.,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i13,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,VEGFA_COTJA,Vascular endothelial growth factor A,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,KEGG:cjo:107311307`KO:K05448,.,PF00341.17^PDGF^PDGF/VEGF domain^143-221^E:8.7e-26,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i5,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i4,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,VEGFA_COTJA,Vascular endothelial growth factor A,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,KEGG:cjo:107311307`KO:K05448,.,PF00341.17^PDGF^PDGF/VEGF domain^143-221^E:8.7e-26,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i12,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,VEGFA_COTJA,Vascular endothelial growth factor A,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,KEGG:cjo:107311307`KO:K05448,.,PF00341.17^PDGF^PDGF/VEGF domain^143-221^E:1.3e-25,PF14554.6^VEGF_C^VEGF heparin-binding domain^230-283^E:3.6e-30,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i14,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i15,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN6537_c0_g1_i10,DN6537_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN12208_c0_g1_i6,DN12208_c0_g1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:hsa:2202`KO:K18262,ENOG410YCRW^epidermal growth factor-activated receptor activity,.,NA,NA,NA,NA,,
no,AD,EGF,DN12208_c0_g1_i1,DN12208_c0_g1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:hsa:2202`KO:K18262,ENOG410YCRW^epidermal growth factor-activated receptor activity,.,NA,NA,NA,NA,,
no,AD,EGF,DN12208_c0_g1_i2,DN12208_c0_g1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,KEGG:hsa:2202`KO:K18262,ENOG410YCRW^epidermal growth factor-activated receptor activity,PF07645.15^EGF_CA^Calcium-binding EGF domain^1-39^E:1.1e-06,PF12662.7^cEGF^Complement Clr-like EGF-like^21-44^E:2.1e-06,PF07645.15^EGF_CA^Calcium-binding EGF domain^41-74^E:3.8e-07,PF12661.7^hEGF^Human growth factor-like EGF^55-71^E:0.08,PF12662.7^cEGF^Complement Clr-like EGF-like^63-84^E:1.8e-07,,
no,AD,EGF,DN12208_c0_g1_i4,DN12208_c0_g1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,KEGG:hsa:2202`KO:K18262,ENOG410YCRW^epidermal growth factor-activated receptor activity,PF07645.15^EGF_CA^Calcium-binding EGF domain^47-74^E:2.3e-07,PF07645.15^EGF_CA^Calcium-binding EGF domain^134-173^E:1.9e-14,PF12661.7^hEGF^Human growth factor-like EGF^151-166^E:0.00046,PF12662.7^cEGF^Complement Clr-like EGF-like^157-178^E:2.4e-07,PF07645.15^EGF_CA^Calcium-binding EGF domain^175-213^E:2.4e-08,,
no,AD,EGF,DN12208_c0_g1_i8,DN12208_c0_g1,FBLN3_HUMAN,EGF-containing fibulin-like extracellular matrix protein 1,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:hsa:2202`KO:K18262,ENOG410YCRW^epidermal growth factor-activated receptor activity,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i4,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},CREL1_BOVIN,Protein disulfide isomerase CRELD1 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:bta:504854,ENOG41107X2^cysteine-rich with egf-like domains,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^35-87^E:7.3e-05,PF00053.24^Laminin_EGF^Laminin EGF domain^152-194^E:0.00011,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i19,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:171508,ENOG41107X2^cysteine-rich with egf-like domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i17,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:171508,ENOG41107X2^cysteine-rich with egf-like domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i15,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:171508,ENOG41107X2^cysteine-rich with egf-like domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i18,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:171508,ENOG41107X2^cysteine-rich with egf-like domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i23,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:171508,ENOG41107X2^cysteine-rich with egf-like domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7773_c0_g1_i2,DN7773_c0_g1,CREL1_MOUSE,Protein disulfide isomerase Creld1 {ECO:0000305},CREL1_RAT,Protein disulfide isomerase Creld1 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:rno:312638,ENOG41107X2^cysteine-rich with egf-like domains,PF00053.24^Laminin_EGF^Laminin EGF domain^132-174^E:0.0001,NA,NA,NA,NA,,
no,AD,EGF,DN6870_c0_g1_i1,DN6870_c0_g1,EGFL7_HUMAN,Epidermal growth factor-like protein 7,EGFL7_HUMAN,Epidermal growth factor-like protein 7,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,KEGG:hsa:51162,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07645.15^EGF_CA^Calcium-binding EGF domain^10-49^E:1.7e-10,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^14-49^E:9.2e-09,NA,NA,NA,,
no,AD,EGF,DN6870_c0_g1_i3,DN6870_c0_g1,EGFL7_HUMAN,Epidermal growth factor-like protein 7,EGFL7_HUMAN,Epidermal growth factor-like protein 7,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,KEGG:hsa:51162,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07645.15^EGF_CA^Calcium-binding EGF domain^10-49^E:1.4e-10,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^14-49^E:7.4e-09,NA,NA,NA,,
no,AD,EGF,DN6870_c0_g1_i2,DN6870_c0_g1,EGFL7_HUMAN,Epidermal growth factor-like protein 7,EGFL7_HUMAN,Epidermal growth factor-like protein 7,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,KEGG:hsa:51162,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07645.15^EGF_CA^Calcium-binding EGF domain^10-49^E:1.7e-10,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^14-49^E:9.2e-09,NA,NA,NA,,
no,AD,EGF,DN6870_c0_g2_i1,DN6870_c0_g2,EGFL7_HUMAN,Epidermal growth factor-like protein 7,EGFL7_HUMAN,Epidermal growth factor-like protein 7,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,KEGG:hsa:51162,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),PF07546.13^EMI^EMI domain^28-95^E:1e-21,PF12661.7^hEGF^Human growth factor-like EGF^112-130^E:0.015,NA,NA,NA,,
no,AD,EGF,DN75041_c0_g1_i1,DN75041_c0_g1,SVEP1_MOUSE,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:64817`KO:K17495,ENOG410XPJ1^c-type lectin domain family,.,NA,NA,NA,NA,,
no,AD,EGF,DN75041_c0_g1_i2,DN75041_c0_g1,SVEP1_MOUSE,"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:64817`KO:K17495,ENOG410XPJ1^c-type lectin domain family,.,NA,NA,NA,NA,,
no,AD,EGF,DN5900_c0_g2_i1,DN5900_c0_g2,MEGF6_RAT,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:rno:65049,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN5900_c0_g2_i5,DN5900_c0_g2,MEGF6_RAT,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:rno:65049,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN2302_c0_g2_i1,DN2302_c0_g2,FBLN4_CRIGR,EGF-containing fibulin-like extracellular matrix protein 2,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0048251^biological_process^elastic fiber assembly,NA,NA,.,NA,NA,NA,NA,KEGG:cge:100736553`KO:K19866,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN7253_c0_g1_i3,DN7253_c0_g1,PEAR1_MOUSE,Platelet endothelial aggregation receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:73182,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7253_c0_g1_i2,DN7253_c0_g1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,KEGG:hsa:375033,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^22-65^E:0.0072,PF12661.7^hEGF^Human growth factor-like EGF^24-43^E:0.012,PF00053.24^Laminin_EGF^Laminin EGF domain^65-109^E:0.0049,PF12661.7^hEGF^Human growth factor-like EGF^67-86^E:0.0091,PF00053.24^Laminin_EGF^Laminin EGF domain^109-148^E:0.006,,
no,AD,EGF,DN7253_c0_g1_i13,DN7253_c0_g1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,KEGG:hsa:375033,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^188-221^E:0.014,PF12661.7^hEGF^Human growth factor-like EGF^230-250^E:0.082,PF00053.24^Laminin_EGF^Laminin EGF domain^272-315^E:0.01,PF12661.7^hEGF^Human growth factor-like EGF^274-293^E:0.017,PF00053.24^Laminin_EGF^Laminin EGF domain^315-359^E:0.0018,,
no,AD,EGF,DN7253_c0_g1_i10,DN7253_c0_g1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,.,NA,NA,NA,NA,KEGG:hsa:375033,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7253_c0_g1_i9,DN7253_c0_g1,PEAR1_MOUSE,Platelet endothelial aggregation receptor 1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0005886^cellular_component^plasma membrane,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,KEGG:hsa:375033,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^64-108^E:0.00039,PF12661.7^hEGF^Human growth factor-like EGF^66-85^E:0.0092,PF00053.24^Laminin_EGF^Laminin EGF domain^108-147^E:0.0064,PF12661.7^hEGF^Human growth factor-like EGF^155-174^E:0.00079,PF12661.7^hEGF^Human growth factor-like EGF^241-260^E:0.057,,
no,AD,EGF,DN7253_c0_g1_i12,DN7253_c0_g1,MEG10_XENTR,Multiple epidermal growth factor-like domains protein 10,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005112^molecular_function^Notch binding,GO:0043277^biological_process^apoptotic cell clearance,GO:0007155^biological_process^cell adhesion,.,NA,NA,NA,NA,KEGG:xtr:780183,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN7253_c0_g1_i1,DN7253_c0_g1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,PEAR1_HUMAN,Platelet endothelial aggregation receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,GO:0016021^cellular_component^integral component of membrane,GO:0001891^cellular_component^phagocytic cup,GO:0038023^molecular_function^signaling receptor activity,GO:0045746^biological_process^negative regulation of Notch signaling pathway,GO:0014065^biological_process^phosphatidylinositol 3-kinase signaling,KEGG:hsa:375033,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^16-48^E:0.014,PF12661.7^hEGF^Human growth factor-like EGF^56-75^E:0.0007,PF12661.7^hEGF^Human growth factor-like EGF^142-161^E:0.051,PF00053.24^Laminin_EGF^Laminin EGF domain^183-226^E:0.0084,PF12661.7^hEGF^Human growth factor-like EGF^228-247^E:0.017,,
no,AD,EGF,DN10375_c1_g1_i2,DN10375_c1_g1,ESM1_MOUSE,Endothelial cell-specific molecule 1,ESM1_MOUSE,Endothelial cell-specific molecule 1,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,KEGG:mmu:71690,ENOG410XQWV^multiple EGF-like-domains,PF00219.18^IGFBP^Insulin-like growth factor binding protein^28-83^E:9.3e-09,NA,NA,NA,NA,,
no,AD,EGF,DN10375_c1_g1_i1,DN10375_c1_g1,ESM1_MOUSE,Endothelial cell-specific molecule 1,ESM1_MOUSE,Endothelial cell-specific molecule 1,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,KEGG:mmu:71690,ENOG410XQWV^multiple EGF-like-domains,PF00219.18^IGFBP^Insulin-like growth factor binding protein^28-83^E:7e-09,NA,NA,NA,NA,,
no,AD,EGF,DN10375_c1_g1_i3,DN10375_c1_g1,ESM1_MOUSE,Endothelial cell-specific molecule 1,ESM1_MOUSE,Endothelial cell-specific molecule 1,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,GO:0005576^cellular_component^extracellular region,GO:0005171^molecular_function^hepatocyte growth factor receptor binding,GO:0005520^molecular_function^insulin-like growth factor binding,GO:0005178^molecular_function^integrin binding,GO:0001525^biological_process^angiogenesis,KEGG:mmu:71690,ENOG410XQWV^multiple EGF-like-domains,PF00219.18^IGFBP^Insulin-like growth factor binding protein^28-83^E:3.5e-09,NA,NA,NA,NA,,
no,AD,EGF,DN94540_c0_g1_i1,DN94540_c0_g1,MEGF8_MOUSE,Multiple epidermal growth factor-like domains protein 8,MEGF8_MOUSE,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,KEGG:mmu:269878,ENOG410YF0N^Multiple EGF-like-domains 8,PF00431.20^CUB^CUB domain^5-95^E:6.4e-14,"PF13418.6^Kelch_4^Galactose oxidase, central domain^189-233^E:1.8e-09","PF13415.6^Kelch_3^Galactose oxidase, central domain^197-233^E:2.8e-06",PF01344.25^Kelch_1^Kelch motif^197-227^E:0.00022,PF07646.15^Kelch_2^Kelch motif^197-227^E:0.00017,,
no,AD,EGF,DN76510_c0_g1_i1,DN76510_c0_g1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00028.17^Cadherin^Cadherin domain^17-108^E:5.2e-23,PF00028.17^Cadherin^Cadherin domain^124-202^E:1.5e-12,NA,NA,NA,,
no,AD,EGF,DN14171_c0_g1_i2,DN14171_c0_g1,CELR2_RAT,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00008.27^EGF^EGF-like domain^105-135^E:0.00015,PF00008.27^EGF^EGF-like domain^145-173^E:0.00012,PF07645.15^EGF_CA^Calcium-binding EGF domain^149-173^E:0.0027,PF12661.7^hEGF^Human growth factor-like EGF^150-171^E:5.2e-05,PF02210.24^Laminin_G_2^Laminin G domain^208-366^E:4.7e-25,,
no,AD,EGF,DN14171_c0_g1_i4,DN14171_c0_g1,CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,.,NA,NA,NA,NA,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN14171_c0_g2_i3,DN14171_c0_g2,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00008.27^EGF^EGF-like domain^210-238^E:4.7e-06,PF12661.7^hEGF^Human growth factor-like EGF^215-236^E:0.00014,PF02210.24^Laminin_G_2^Laminin G domain^273-431^E:3.1e-26,PF00054.23^Laminin_G_1^Laminin G domain^273-435^E:6.9e-16,PF00008.27^EGF^EGF-like domain^456-486^E:2.3e-07,,
no,AD,EGF,DN14171_c0_g2_i2,DN14171_c0_g2,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00008.27^EGF^EGF-like domain^210-238^E:4.6e-06,PF12661.7^hEGF^Human growth factor-like EGF^215-236^E:0.00014,PF02210.24^Laminin_G_2^Laminin G domain^273-431^E:3.1e-26,PF00054.23^Laminin_G_1^Laminin G domain^273-435^E:6.9e-16,PF00008.27^EGF^EGF-like domain^456-486^E:2.2e-07,,
no,AD,EGF,DN14171_c0_g2_i1,DN14171_c0_g2,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00008.27^EGF^EGF-like domain^210-238^E:4.7e-06,PF12661.7^hEGF^Human growth factor-like EGF^215-236^E:0.00014,PF02210.24^Laminin_G_2^Laminin G domain^273-431^E:3.2e-26,PF00054.23^Laminin_G_1^Laminin G domain^273-435^E:7e-16,PF00008.27^EGF^EGF-like domain^456-486^E:2.3e-07,,
no,AD,EGF,DN14171_c0_g2_i4,DN14171_c0_g2,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00008.27^EGF^EGF-like domain^210-238^E:4.6e-06,PF12661.7^hEGF^Human growth factor-like EGF^215-236^E:0.00014,PF02210.24^Laminin_G_2^Laminin G domain^273-431^E:3.1e-26,PF00054.23^Laminin_G_1^Laminin G domain^273-435^E:6.9e-16,PF00008.27^EGF^EGF-like domain^456-486^E:2.2e-07,,
no,AD,EGF,DN6641_c2_g1_i2,DN6641_c2_g1,CELR2_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 2,CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00028.17^Cadherin^Cadherin domain^72-165^E:5.3e-19,PF00028.17^Cadherin^Cadherin domain^181-274^E:4.3e-20,PF00028.17^Cadherin^Cadherin domain^288-379^E:5.3e-23,PF00028.17^Cadherin^Cadherin domain^395-485^E:5.7e-22,PF00028.17^Cadherin^Cadherin domain^501-587^E:9.5e-18,,
no,AD,EGF,DN62317_c0_g1_i2,DN62317_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN62317_c0_g1_i1,DN62317_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^2-33^E:0.024,PF00053.24^Laminin_EGF^Laminin EGF domain^37-76^E:0.0064,PF12661.7^hEGF^Human growth factor-like EGF^82-101^E:0.00038,NA,NA,,
no,AD,EGF,DN9781_c0_g1_i4,DN9781_c0_g1,VEGFA_PIG,Vascular endothelial growth factor A,PLGF_HUMAN,Placenta growth factor,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030141^cellular_component^secretory granule,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:5228`KO:K16859,ENOG410YNR0^Placental growth factor,PF00341.17^PDGF^PDGF/VEGF domain^90-168^E:5.6e-26,NA,NA,NA,NA,,
no,AD,EGF,DN9781_c0_g1_i10,DN9781_c0_g1,VEGFA_PIG,Vascular endothelial growth factor A,PLGF_HUMAN,Placenta growth factor,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030141^cellular_component^secretory granule,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:5228`KO:K16859,ENOG410YNR0^Placental growth factor,PF00341.17^PDGF^PDGF/VEGF domain^90-168^E:6.8e-26,NA,NA,NA,NA,,
no,AD,EGF,DN9781_c0_g1_i8,DN9781_c0_g1,VEGFA_SHEEP,Vascular endothelial growth factor A,.,NA,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0001525^biological_process^angiogenesis,GO:0097475^biological_process^motor neuron migration,.,NA,NA,NA,NA,KEGG:oas:443103`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN9781_c0_g1_i11,DN9781_c0_g1,VEGFA_PIG,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0030141^cellular_component^secretory granule,.,NA,NA,NA,NA,KEGG:ssc:397157`KO:K05448,ENOG410ZWYU^Vascular endothelial growth factor A,.,NA,NA,NA,NA,,
no,AD,EGF,DN18004_c0_g1_i1,DN18004_c0_g1,EGFL6_HUMAN,Epidermal growth factor-like protein 6,EGFL6_HUMAN,Epidermal growth factor-like protein 6,GO:0005604^cellular_component^basement membrane,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,GO:0005604^cellular_component^basement membrane,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,KEGG:hsa:25975,"ENOG410XR84^EGF-like-domain, multiple 6",PF07645.15^EGF_CA^Calcium-binding EGF domain^105-136^E:8.2e-07,PF12662.7^cEGF^Complement Clr-like EGF-like^166-188^E:3.7e-06,PF07645.15^EGF_CA^Calcium-binding EGF domain^185-218^E:5.4e-10,PF07645.15^EGF_CA^Calcium-binding EGF domain^230-269^E:1.1e-10,PF12947.7^EGF_3^EGF domain^234-269^E:2.1e-09,,
no,AD,EGF,DN18004_c0_g1_i2,DN18004_c0_g1,EGFL6_HUMAN,Epidermal growth factor-like protein 6,EGFL6_HUMAN,Epidermal growth factor-like protein 6,GO:0005604^cellular_component^basement membrane,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,GO:0005604^cellular_component^basement membrane,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,KEGG:hsa:25975,"ENOG410XR84^EGF-like-domain, multiple 6",PF12662.7^cEGF^Complement Clr-like EGF-like^126-148^E:3.4e-06,PF07645.15^EGF_CA^Calcium-binding EGF domain^145-178^E:4.9e-10,PF07645.15^EGF_CA^Calcium-binding EGF domain^190-229^E:1e-10,PF12947.7^EGF_3^EGF domain^194-229^E:1.9e-09,PF12661.7^hEGF^Human growth factor-like EGF^201-222^E:0.0016,,
no,AD,EGF,DN18004_c0_g1_i3,DN18004_c0_g1,EGFL6_MOUSE,Epidermal growth factor-like protein 6,EGFL6_HUMAN,Epidermal growth factor-like protein 6,GO:0005604^cellular_component^basement membrane,GO:0031012^cellular_component^extracellular matrix,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,GO:0005604^cellular_component^basement membrane,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005178^molecular_function^integrin binding,KEGG:hsa:25975,"ENOG410XR84^EGF-like-domain, multiple 6","PF00629.23^MAM^MAM domain, meprin/A5/mu^50-170^E:1.8e-17",NA,NA,NA,NA,,
no,AD,EGF,DN42726_c0_g1_i1,DN42726_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,.,NA,NA,NA,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,.,NA,NA,NA,NA,,
no,AD,EGF,DN42726_c0_g2_i6,DN42726_c0_g2,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^28-179^E:2.6e-12,PF00008.27^EGF^EGF-like domain^725-758^E:3.5e-05,PF12661.7^hEGF^Human growth factor-like EGF^728-755^E:0.039,PF00008.27^EGF^EGF-like domain^767-794^E:5.1e-05,PF12661.7^hEGF^Human growth factor-like EGF^773-791^E:0.006,,
no,AD,EGF,DN42726_c0_g2_i4,DN42726_c0_g2,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF12661.7^hEGF^Human growth factor-like EGF^462-480^E:0.02,PF07974.13^EGF_2^EGF-like domain^549-581^E:3.7e-05,PF12661.7^hEGF^Human growth factor-like EGF^558-576^E:0.0089,NA,NA,,
no,AD,EGF,DN42726_c0_g2_i5,DN42726_c0_g2,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^28-179^E:2.3e-12,PF00008.27^EGF^EGF-like domain^725-758^E:3.3e-05,PF12661.7^hEGF^Human growth factor-like EGF^728-755^E:0.04,PF00008.27^EGF^EGF-like domain^767-794^E:4.8e-05,PF12661.7^hEGF^Human growth factor-like EGF^773-791^E:0.0056,,
no,AD,EGF,DN57173_c0_g1_i1,DN57173_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,KEGG:hsa:220001,ENOG4110VWF^von Willebrand factor C and EGF domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN57173_c0_g1_i2,DN57173_c0_g1,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,VWCE_HUMAN,von Willebrand factor C and EGF domain-containing protein,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0098586^biological_process^cellular response to virus,NA,KEGG:hsa:220001,ENOG4110VWF^von Willebrand factor C and EGF domains,PF00093.18^VWC^von Willebrand factor type C domain^27-82^E:3.6e-06,NA,NA,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i1,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF00341.17^PDGF^PDGF/VEGF domain^62-142^E:6.6e-24,PF03128.14^CXCXC^CXCXC repeat^214-226^E:0.00048,PF03128.14^CXCXC^CXCXC repeat^262-274^E:0.0022,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i5,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF03128.14^CXCXC^CXCXC repeat^117-129^E:0.00033,PF03128.14^CXCXC^CXCXC repeat^165-177^E:0.0015,NA,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i6,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF03128.14^CXCXC^CXCXC repeat^46-58^E:0.00022,PF03128.14^CXCXC^CXCXC repeat^94-106^E:0.001,NA,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i4,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF00341.17^PDGF^PDGF/VEGF domain^164-244^E:1e-23,PF03128.14^CXCXC^CXCXC repeat^316-328^E:0.00065,PF03128.14^CXCXC^CXCXC repeat^364-376^E:0.003,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i2,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF03128.14^CXCXC^CXCXC repeat^72-84^E:0.00026,PF03128.14^CXCXC^CXCXC repeat^120-132^E:0.0012,NA,NA,NA,,
no,AD,EGF,DN14871_c0_g1_i3,DN14871_c0_g1,VEGFC_HUMAN,Vascular endothelial growth factor C,VEGFC_HUMAN,Vascular endothelial growth factor C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:7424`KO:K05449,ENOG410YGVZ^vascular endothelial growth factor c,PF00341.17^PDGF^PDGF/VEGF domain^164-244^E:8.8e-24,PF03128.14^CXCXC^CXCXC repeat^316-328^E:0.00059,PF03128.14^CXCXC^CXCXC repeat^364-376^E:0.0027,NA,NA,,
no,AD,EGF,DN31014_c0_g1_i6,DN31014_c0_g1,CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,.,NA,NA,NA,NA,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN31014_c0_g1_i7,DN31014_c0_g1,CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,.,NA,NA,NA,NA,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN31014_c0_g1_i4,DN31014_c0_g1,CELR2_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},CELR2_RAT,Cadherin EGF LAG seven-pass G-type receptor 2 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007166^biological_process^cell surface receptor signaling pathway,KEGG:hsa:1952`KO:K04601,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF16489.5^GAIN^GPCR-Autoproteolysis INducing (GAIN) domain^27-96^E:2.7e-14,"PF01825.21^GPS^GPCR proteolysis site, GPS, motif^125-170^E:6.1e-16",PF00002.24^7tm_2^7 transmembrane receptor (Secretin family)^184-411^E:1.4e-38,NA,NA,,
no,AD,EGF,DN72966_c0_g1_i10,DN72966_c0_g1,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,.,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN72966_c0_g1_i1,DN72966_c0_g1,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,KEGG:hsa:1954,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN72966_c0_g1_i13,DN72966_c0_g1,MEGF8_MOUSE,Multiple epidermal growth factor-like domains protein 8,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:269878,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN72966_c0_g1_i8,DN72966_c0_g1,MEGF8_MOUSE,Multiple epidermal growth factor-like domains protein 8,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,.,NA,NA,NA,NA,KEGG:mmu:269878,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
no,AD,EGF,DN63840_c0_g1_i1,DN63840_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,PF12662.7^cEGF^Complement Clr-like EGF-like^17-38^E:1e-06,PF07645.15^EGF_CA^Calcium-binding EGF domain^36-74^E:4.4e-05,PF07645.15^EGF_CA^Calcium-binding EGF domain^76-115^E:7.2e-09,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^80-115^E:4.7e-09,PF12661.7^hEGF^Human growth factor-like EGF^90-106^E:0.015,,
no,AD,EGF,DN9539_c0_g1_i13,DN9539_c0_g1,CELR3_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,.,NA,NA,NA,NA,KEGG:hsa:1951`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN9539_c0_g1_i4,DN9539_c0_g1,CELR3_HUMAN,Cadherin EGF LAG seven-pass G-type receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,.,NA,NA,NA,NA,KEGG:hsa:1951`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN9539_c0_g1_i9,DN9539_c0_g1,CELR3_RAT,Cadherin EGF LAG seven-pass G-type receptor 3,CELR3_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,KEGG:mmu:107934`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF16489.5^GAIN^GPCR-Autoproteolysis INducing (GAIN) domain^108-353^E:2.8e-64,"PF01825.21^GPS^GPCR proteolysis site, GPS, motif^381-426^E:9.9e-08",PF00002.24^7tm_2^7 transmembrane receptor (Secretin family)^441-623^E:2.6e-43,NA,NA,,
no,AD,EGF,DN9539_c0_g1_i12,DN9539_c0_g1,CELR3_RAT,Cadherin EGF LAG seven-pass G-type receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,.,NA,NA,NA,NA,KEGG:rno:83466`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN9539_c0_g1_i10,DN9539_c0_g1,CELR3_RAT,Cadherin EGF LAG seven-pass G-type receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,.,NA,NA,NA,NA,KEGG:rno:83466`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN9539_c0_g1_i1,DN9539_c0_g1,CELR3_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 3,CELR3_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 3,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0007413^biological_process^axonal fasciculation,KEGG:mmu:107934`KO:K04602,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN1826_c0_g1_i12,DN1826_c0_g1,MFGM_MOUSE,Lactadherin,MFGM_MOUSE,Lactadherin,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005178^molecular_function^integrin binding,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005178^molecular_function^integrin binding,KEGG:mmu:17304`KO:K17253,ENOG41114BV^Milk fat globule-EGF factor 8 protein,PF00008.27^EGF^EGF-like domain^28-59^E:7.6e-06,PF12661.7^hEGF^Human growth factor-like EGF^33-56^E:0.00013,PF00008.27^EGF^EGF-like domain^69-104^E:8.8e-09,PF12661.7^hEGF^Human growth factor-like EGF^74-101^E:0.026,PF00008.27^EGF^EGF-like domain^113-142^E:1.6e-09,,
no,AD,EGF,DN1826_c0_g1_i7,DN1826_c0_g1,MFGM_MOUSE,Lactadherin,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005178^molecular_function^integrin binding,.,NA,NA,NA,NA,KEGG:mmu:17304`KO:K17253,ENOG41114BV^Milk fat globule-EGF factor 8 protein,.,NA,NA,NA,NA,,
no,AD,EGF,DN8609_c0_g1_i2,DN8609_c0_g1,DKK2_HUMAN,Dickkopf-related protein 2,.,NA,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,.,NA,NA,NA,NA,KEGG:hsa:27123`KO:K02165,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN1039_c0_g1_i5,DN1039_c0_g1,SCUB2_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000303|PubMed:19480626}",.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0008289^molecular_function^lipid binding,.,NA,NA,NA,NA,KEGG:hsa:57758,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN1039_c0_g1_i3,DN1039_c0_g1,SCUB2_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000303|PubMed:19480626}",SCUB2_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000303|PubMed:19480626}",GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0008289^molecular_function^lipid binding,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0008289^molecular_function^lipid binding,KEGG:hsa:57758,.,PF07645.15^EGF_CA^Calcium-binding EGF domain^28-67^E:1.9e-07,PF12947.7^EGF_3^EGF domain^32-67^E:3.2e-09,PF00008.27^EGF^EGF-like domain^37-63^E:0.00023,PF12661.7^hEGF^Human growth factor-like EGF^39-60^E:0.023,PF07645.15^EGF_CA^Calcium-binding EGF domain^69-109^E:0.0049,,
no,AD,EGF,DN1039_c0_g1_i6,DN1039_c0_g1,SCUB2_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000303|PubMed:19480626}",SCUB2_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000303|PubMed:19480626}",GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0008289^molecular_function^lipid binding,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005509^molecular_function^calcium ion binding,GO:0008289^molecular_function^lipid binding,KEGG:hsa:57758,.,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^6-53^E:5.1e-14,PF07699.13^Ephrin_rec_like^Putative ephrin-receptor like^62-109^E:8.3e-16,PF00431.20^CUB^CUB domain^114-223^E:6.5e-20,NA,NA,,
no,AD,EGF,DN1039_c0_g1_i1,DN1039_c0_g1,SCUB2_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000250|UniProtKB:Q9NQ36}",.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0097108^molecular_function^hedgehog family protein binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i10,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,.,NA,NA,NA,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,.,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i25,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF12661.7^hEGF^Human growth factor-like EGF^799-814^E:0.027,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i15,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^424-581^E:2.7e-10,PF12661.7^hEGF^Human growth factor-like EGF^1237-1252^E:0.064,PF07974.13^EGF_2^EGF-like domain^1580-1607^E:5.7e-05,PF12661.7^hEGF^Human growth factor-like EGF^1584-1602^E:0.078,PF12661.7^hEGF^Human growth factor-like EGF^1648-1666^E:0.03,,
no,AD,EGF,DN30982_c0_g1_i13,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,.,NA,NA,NA,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,.,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i21,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^424-581^E:1.7e-10,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i23,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^11-168^E:4.8e-11,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i11,DN30982_c0_g1,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,.,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),.,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i1,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF07974.13^EGF_2^EGF-like domain^330-357^E:8.9e-06,PF12661.7^hEGF^Human growth factor-like EGF^334-352^E:0.013,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i18,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^424-581^E:2.7e-10,PF12661.7^hEGF^Human growth factor-like EGF^1237-1252^E:0.064,PF07974.13^EGF_2^EGF-like domain^1580-1607^E:5.7e-05,PF12661.7^hEGF^Human growth factor-like EGF^1584-1602^E:0.078,PF12661.7^hEGF^Human growth factor-like EGF^1648-1666^E:0.03,,
no,AD,EGF,DN30982_c0_g1_i3,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,.,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i6,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^57-214^E:1e-10,NA,NA,NA,NA,,
no,AD,EGF,DN30982_c0_g1_i2,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF12661.7^hEGF^Human growth factor-like EGF^151-169^E:0.0044,PF07974.13^EGF_2^EGF-like domain^179-206^E:0.00014,PF12661.7^hEGF^Human growth factor-like EGF^183-201^E:0.041,PF12661.7^hEGF^Human growth factor-like EGF^247-265^E:0.0054,PF12661.7^hEGF^Human growth factor-like EGF^279-295^E:0.025,,
no,AD,EGF,DN30982_c0_g1_i12,DN30982_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF00094.25^VWD^von Willebrand factor type D domain^424-581^E:1.7e-10,NA,NA,NA,NA,,
no,AD,EGF,DN9884_c0_g1_i3,DN9884_c0_g1,DKK2_HUMAN,Dickkopf-related protein 2,DKK2_HUMAN,Dickkopf-related protein 2,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,KEGG:hsa:27123`KO:K02165,ENOG410XQWV^multiple EGF-like-domains,PF04706.12^Dickkopf_N^Dickkopf N-terminal cysteine-rich region^3-28^E:1e-07,NA,NA,NA,NA,,
no,AD,EGF,DN9884_c0_g1_i2,DN9884_c0_g1,DKK2_HUMAN,Dickkopf-related protein 2,DKK2_HUMAN,Dickkopf-related protein 2,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,KEGG:hsa:27123`KO:K02165,ENOG410XQWV^multiple EGF-like-domains,PF04706.12^Dickkopf_N^Dickkopf N-terminal cysteine-rich region^32-82^E:1.3e-16,NA,NA,NA,NA,,
no,AD,EGF,DN9884_c0_g1_i1,DN9884_c0_g1,DKK2_MOUSE,Dickkopf-related protein 2,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0039706^molecular_function^co-receptor binding,GO:0048019^molecular_function^receptor antagonist activity,GO:0007275^biological_process^multicellular organism development,.,NA,NA,NA,NA,KEGG:mmu:56811`KO:K02165,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN1368_c0_g2_i1,DN1368_c0_g2,SCUB3_HUMAN,"Signal peptide, CUB and EGF-like domain-containing protein 3",.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0022617^biological_process^extracellular matrix disassembly,.,NA,NA,NA,NA,KEGG:hsa:222663,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),.,NA,NA,NA,NA,,
no,AD,EGF,DN18379_c0_g1_i2,DN18379_c0_g1,SREC_MOUSE,Scavenger receptor class F member 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030169^molecular_function^low-density lipoprotein particle binding,GO:0005044^molecular_function^scavenger receptor activity,GO:0007155^biological_process^cell adhesion,.,NA,NA,NA,NA,KEGG:mmu:380713,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g1_i2,DN6240_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,PF04577.14^DUF563^Protein of unknown function (DUF563)^245-469^E:1e-27,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g1_i9,DN6240_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g1_i6,DN6240_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,PF04577.14^DUF563^Protein of unknown function (DUF563)^2-76^E:2.5e-16,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g1_i1,DN6240_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g1_i8,DN6240_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,PF04577.14^DUF563^Protein of unknown function (DUF563)^245-469^E:1e-27,NA,NA,NA,NA,,
no,AD,EGF,DN6240_c0_g2_i1,DN6240_c0_g2,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
yes,AD,EGF,DN93689_c0_g1_i1,DN93689_c0_g1,EGF_CANLF,Pro-epidermal growth factor,EGF_CANLF,Pro-epidermal growth factor,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005509^molecular_function^calcium ion binding,GO:0008083^molecular_function^growth factor activity,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005509^molecular_function^calcium ion binding,GO:0008083^molecular_function^growth factor activity,KEGG:cfa:403657`KO:K04357,ENOG410ZVIM^epidermal growth factor,PF00058.17^Ldl_recept_b^Low-density lipoprotein receptor repeat class B^25-65^E:3.8e-08,PF00058.17^Ldl_recept_b^Low-density lipoprotein receptor repeat class B^68-107^E:8.1e-12,NA,NA,NA,,
yes,AD,EGF,DN93689_c0_g1_i2,DN93689_c0_g1,EGF_CANLF,Pro-epidermal growth factor,EGF_CANLF,Pro-epidermal growth factor,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005509^molecular_function^calcium ion binding,GO:0008083^molecular_function^growth factor activity,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005509^molecular_function^calcium ion binding,GO:0008083^molecular_function^growth factor activity,KEGG:cfa:403657`KO:K04357,ENOG410ZVIM^epidermal growth factor,PF07645.15^EGF_CA^Calcium-binding EGF domain^23-63^E:9.1e-07,PF07645.15^EGF_CA^Calcium-binding EGF domain^381-420^E:1.7e-07,PF00008.27^EGF^EGF-like domain^426-451^E:4.2e-05,PF14670.6^FXa_inhibition^Coagulation Factor Xa inhibitory site^468-501^E:3.8e-08,PF00058.17^Ldl_recept_b^Low-density lipoprotein receptor repeat class B^549-589^E:1.1e-05,,
no,AD,EGF,DN32059_c2_g1_i1,DN32059_c2_g1,.,NA,MFGM_PIG,Lactadherin,.,NA,NA,NA,NA,GO:0002080^cellular_component^acrosomal membrane,GO:0005576^cellular_component^extracellular region,GO:0001525^biological_process^angiogenesis,GO:0007155^biological_process^cell adhesion,GO:0007338^biological_process^single fertilization,.,ENOG41114BV^Milk fat globule-EGF factor 8 protein,.,NA,NA,NA,NA,,
no,AD,EGF,DN1663_c0_g1_i7,DN1663_c0_g1,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,KEGG:mmu:230316,ENOG410XPEG^laminin beta,PF00053.24^Laminin_EGF^Laminin EGF domain^100-147^E:4.1e-07,PF00053.24^Laminin_EGF^Laminin EGF domain^150-193^E:5.9e-07,PF00053.24^Laminin_EGF^Laminin EGF domain^197-239^E:4.8e-09,PF00053.24^Laminin_EGF^Laminin EGF domain^242-286^E:5.5e-05,PF00053.24^Laminin_EGF^Laminin EGF domain^293-341^E:2.6e-07,,
no,AD,EGF,DN1663_c0_g1_i14,DN1663_c0_g1,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,KEGG:mmu:230316,ENOG410XPEG^laminin beta,PF00053.24^Laminin_EGF^Laminin EGF domain^100-147^E:4.1e-07,PF00053.24^Laminin_EGF^Laminin EGF domain^150-193^E:5.9e-07,PF00053.24^Laminin_EGF^Laminin EGF domain^197-239^E:4.8e-09,PF00053.24^Laminin_EGF^Laminin EGF domain^242-286^E:5.5e-05,PF00053.24^Laminin_EGF^Laminin EGF domain^293-341^E:2.6e-07,,
no,AD,EGF,DN1663_c0_g1_i1,DN1663_c0_g1,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,MEGF9_HUMAN,Multiple epidermal growth factor-like domains protein 9,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,KEGG:hsa:1955,ENOG410XPEG^laminin beta,.,NA,NA,NA,NA,,
no,AD,EGF,DN1663_c0_g1_i12,DN1663_c0_g1,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,MEGF9_HUMAN,Multiple epidermal growth factor-like domains protein 9,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,KEGG:hsa:1955,ENOG410XPEG^laminin beta,.,NA,NA,NA,NA,,
no,AD,EGF,DN1663_c0_g1_i11,DN1663_c0_g1,MEGF9_MOUSE,Multiple epidermal growth factor-like domains protein 9,MEGF9_HUMAN,Multiple epidermal growth factor-like domains protein 9,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,GO:0005604^cellular_component^basement membrane,GO:0016021^cellular_component^integral component of membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0016477^biological_process^cell migration,GO:0034446^biological_process^substrate adhesion-dependent cell spreading,KEGG:hsa:1955,ENOG410XPEG^laminin beta,.,NA,NA,NA,NA,,
no,AD,EGF,DN40361_c0_g1_i3,DN40361_c0_g1,VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:2277`KO:K05449,ENOG4111ICH^c-fos induced growth factor (vascular endothelial growth factor D),PF00341.17^PDGF^PDGF/VEGF domain^16-96^E:5.9e-23,PF03128.14^CXCXC^CXCXC repeat^166-177^E:0.034,NA,NA,NA,,
no,AD,EGF,DN40361_c0_g1_i2,DN40361_c0_g1,VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:2277`KO:K05449,ENOG4111ICH^c-fos induced growth factor (vascular endothelial growth factor D),.,NA,NA,NA,NA,,
no,AD,EGF,DN40361_c0_g1_i4,DN40361_c0_g1,VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:2277`KO:K05449,ENOG4111ICH^c-fos induced growth factor (vascular endothelial growth factor D),PF00341.17^PDGF^PDGF/VEGF domain^111-191^E:1.1e-22,PF03128.14^CXCXC^CXCXC repeat^261-272^E:0.049,NA,NA,NA,,
no,AD,EGF,DN40361_c0_g1_i5,DN40361_c0_g1,VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:2277`KO:K05449,ENOG4111ICH^c-fos induced growth factor (vascular endothelial growth factor D),PF00341.17^PDGF^PDGF/VEGF domain^111-191^E:4e-23,NA,NA,NA,NA,,
no,AD,EGF,DN40361_c0_g1_i1,DN40361_c0_g1,VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},VEGFD_HUMAN,Vascular endothelial growth factor D {ECO:0000312|HGNC:HGNC:3708},GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:2277`KO:K05449,ENOG4111ICH^c-fos induced growth factor (vascular endothelial growth factor D),PF00341.17^PDGF^PDGF/VEGF domain^111-167^E:3.6e-18,NA,NA,NA,NA,,
no,AD,EGF,DN31208_c0_g1_i2,DN31208_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN46883_c0_g1_i1,DN46883_c0_g1,MEGF6_RAT,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:rno:65049,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN46883_c0_g1_i2,DN46883_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,PF07546.13^EMI^EMI domain^9-43^E:3.8e-08,PF12661.7^hEGF^Human growth factor-like EGF^61-81^E:0.0021,PF07645.15^EGF_CA^Calcium-binding EGF domain^89-128^E:2.3e-06,PF12662.7^cEGF^Complement Clr-like EGF-like^110-133^E:8.3e-07,PF07645.15^EGF_CA^Calcium-binding EGF domain^130-169^E:1.4e-08,,
no,AD,EGF,DN162286_c0_g1_i1,DN162286_c0_g1,EGF_HUMAN,Pro-epidermal growth factor,EGF_HUMAN,Pro-epidermal growth factor,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0030665^cellular_component^clathrin-coated vesicle membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:1950`KO:K04357,ENOG410ZVIM^epidermal growth factor,PF07645.15^EGF_CA^Calcium-binding EGF domain^108-148^E:5.7e-09,PF12661.7^hEGF^Human growth factor-like EGF^119-141^E:0.039,PF07645.15^EGF_CA^Calcium-binding EGF domain^150-183^E:2.2e-08,PF00008.27^EGF^EGF-like domain^214-249^E:1.7e-05,NA,,
no,AD,EGF,DN155354_c0_g1_i1,DN155354_c0_g1,EYS_DANRE,Protein eyes shut homolog {ECO:0000303|PubMed:27737822},.,NA,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0033165^cellular_component^interphotoreceptor matrix,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:dre:557044`KO:K19601,ENOG411061Z^EGF-like domain,.,NA,NA,NA,NA,,
no,AD,EGF,DN155407_c0_g1_i1,DN155407_c0_g1,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,KEGG:hsa:1954,ENOG410YF0N^Multiple EGF-like-domains 8,"PF13418.6^Kelch_4^Galactose oxidase, central domain^43-96^E:1.5e-08","PF13415.6^Kelch_3^Galactose oxidase, central domain^55-105^E:3.1e-08",NA,NA,NA,,
no,AD,EGF,DN154348_c0_g1_i1,DN154348_c0_g1,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,.,NA,NA,NA,NA,,
no,AD,EGF,DN168724_c0_g1_i1,DN168724_c0_g1,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,.,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),.,NA,NA,NA,NA,,
no,AD,EGF,DN168724_c0_g1_i4,DN168724_c0_g1,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,.,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),.,NA,NA,NA,NA,,
no,AD,EGF,DN110994_c0_g1_i9,DN110994_c0_g1,STAN_DROME,Protocadherin-like wing polarity protein stan,STAN_DROME,Protocadherin-like wing polarity protein stan,GO:0005911^cellular_component^cell-cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005911^cellular_component^cell-cell junction,GO:0016021^cellular_component^integral component of membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:dme:Dmel_CG11895`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN122505_c0_g1_i1,DN122505_c0_g1,DNER_HUMAN,Delta and Notch-like epidermal growth factor-related receptor,DNER_HUMAN,Delta and Notch-like epidermal growth factor-related receptor,GO:0030425^cellular_component^dendrite,GO:0005769^cellular_component^early endosome,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0005886^cellular_component^plasma membrane,GO:0030425^cellular_component^dendrite,GO:0005769^cellular_component^early endosome,GO:0016021^cellular_component^integral component of membrane,GO:0043025^cellular_component^neuronal cell body,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:92737,ENOG410ZUAK^Delta notch-like EGF repeat containing,PF00008.27^EGF^EGF-like domain^26-54^E:8.1e-05,PF00008.27^EGF^EGF-like domain^277-311^E:2.1e-06,PF12661.7^hEGF^Human growth factor-like EGF^282-308^E:0.0076,PF00008.27^EGF^EGF-like domain^322-346^E:1.7e-05,PF12661.7^hEGF^Human growth factor-like EGF^325-346^E:4.7e-05,,
no,AD,EGF,DN129295_c0_g1_i1,DN129295_c0_g1,MEGF6_HUMAN,Multiple epidermal growth factor-like domains protein 6,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:1953,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN171945_c0_g1_i1,DN171945_c0_g1,CRE2A_XENLA,Cysteine-rich with EGF-like domain protein 2-A,CRE2A_XENLA,Cysteine-rich with EGF-like domain protein 2-A,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,KEGG:xla:495074,.,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^94-149^E:3.8e-06,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^150-190^E:0.0004,PF07645.15^EGF_CA^Calcium-binding EGF domain^294-323^E:1.1e-05,PF07645.15^EGF_CA^Calcium-binding EGF domain^352-392^E:4.4e-11,PF12661.7^hEGF^Human growth factor-like EGF^367-385^E:0.0035,,
no,AD,EGF,DN171945_c0_g1_i2,DN171945_c0_g1,CRE2A_XENLA,Cysteine-rich with EGF-like domain protein 2-A,CRE2B_XENLA,Cysteine-rich with EGF-like domain protein 2-B,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,KEGG:xla:734593,.,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^94-149^E:2.2e-06,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^150-190^E:0.00025,NA,NA,NA,,
no,AD,EGF,DN171945_c0_g1_i6,DN171945_c0_g1,CRE2A_XENLA,Cysteine-rich with EGF-like domain protein 2-A,CRE2B_XENLA,Cysteine-rich with EGF-like domain protein 2-B,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,KEGG:xla:734593,.,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^94-149^E:2.7e-06,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^150-190^E:0.0003,PF07645.15^EGF_CA^Calcium-binding EGF domain^294-319^E:2.1e-06,NA,NA,,
no,AD,EGF,DN171945_c0_g1_i5,DN171945_c0_g1,CRE2A_XENLA,Cysteine-rich with EGF-like domain protein 2-A,CRE2B_XENLA,Cysteine-rich with EGF-like domain protein 2-B,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,KEGG:xla:734593,.,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^94-149^E:2.7e-06,PF11938.8^DUF3456^TLR4 regulator and MIR-interacting MSAP^150-190^E:0.0003,PF07645.15^EGF_CA^Calcium-binding EGF domain^294-319^E:2.1e-06,NA,NA,,
no,AD,EGF,DN171945_c0_g1_i3,DN171945_c0_g1,CRE2B_XENLA,Cysteine-rich with EGF-like domain protein 2-B,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,.,NA,NA,NA,NA,KEGG:xla:734593,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN156560_c0_g1_i1,DN156560_c0_g1,VEGFA_COTJA,Vascular endothelial growth factor A,.,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:cjo:107311307`KO:K05448,.,.,NA,NA,NA,NA,,
yes,AD,EGF,DN235343_c0_g1_i1,DN235343_c0_g1,EGFR_CHICK,Epidermal growth factor receptor,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031965^cellular_component^nuclear membrane,.,NA,NA,NA,NA,KEGG:gga:396494`KO:K04361,ENOG410XNSR^erythroblastic leukemia viral oncogene homolog,.,NA,NA,NA,NA,,
no,AD,EGF,DN270971_c0_g1_i1,DN270971_c0_g1,MEG10_XENTR,Multiple epidermal growth factor-like domains protein 10,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005112^molecular_function^Notch binding,GO:0043277^biological_process^apoptotic cell clearance,GO:0007155^biological_process^cell adhesion,.,NA,NA,NA,NA,KEGG:xtr:780183,ENOG410XQWV^multiple EGF-like-domains,.,NA,NA,NA,NA,,
no,AD,EGF,DN239462_c0_g1_i1,DN239462_c0_g1,EYS_DANRE,Protein eyes shut homolog {ECO:0000303|PubMed:27737822},EYS_DANRE,Protein eyes shut homolog {ECO:0000303|PubMed:27737822},GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0033165^cellular_component^interphotoreceptor matrix,GO:0005509^molecular_function^calcium ion binding,GO:0005929^cellular_component^cilium,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0033165^cellular_component^interphotoreceptor matrix,GO:0005509^molecular_function^calcium ion binding,KEGG:dre:557044`KO:K19601,ENOG411061Z^EGF-like domain,PF00008.27^EGF^EGF-like domain^3-28^E:2.4e-07,PF12661.7^hEGF^Human growth factor-like EGF^4-25^E:7.8e-06,PF07645.15^EGF_CA^Calcium-binding EGF domain^99-129^E:0.0092,PF00008.27^EGF^EGF-like domain^102-131^E:9.4e-08,PF12661.7^hEGF^Human growth factor-like EGF^107-128^E:8e-07,,
no,AD,EGF,DN210199_c0_g1_i1,DN210199_c0_g1,SCUB2_MOUSE,"Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000250|UniProtKB:Q9NQ36}",.,NA,GO:0009986^cellular_component^cell surface,GO:0005615^cellular_component^extracellular space,GO:0019897^cellular_component^extrinsic component of plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0097108^molecular_function^hedgehog family protein binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,EGF,DN242362_c0_g1_i1,DN242362_c0_g1,EOGT_CANLF,EGF domain-specific O-linked N-acetylglucosamine transferase,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,.,NA,NA,NA,NA,KEGG:cfa:494221`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
no,AD,EGF,DN216946_c0_g1_i1,DN216946_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
no,AD,EGF,DN257168_c0_g1_i1,DN257168_c0_g1,VWDE_MOUSE,von Willebrand factor D and EGF domain-containing protein,.,NA,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410XP6K^Notch ligand involved in the mediation of Notch signaling (By similarity),.,NA,NA,NA,NA,,
no,AD,EGF,DN381001_c0_g1_i1,DN381001_c0_g1,TEFF2_HUMAN,Tomoregulin-2,.,NA,GO:0005576^cellular_component^extracellular region,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0009887^biological_process^animal organ morphogenesis,GO:0030336^biological_process^negative regulation of cell migration,.,NA,NA,NA,NA,KEGG:hsa:23671,ENOG4110TEU^transmembrane protein with EGF-like and two follistatin-like domains 2,.,NA,NA,NA,NA,,
no,AD,EGF,DN347607_c0_g1_i1,DN347607_c0_g1,MEGF8_RAT,Multiple epidermal growth factor-like domains protein 8,MEGF8_HUMAN,Multiple epidermal growth factor-like domains protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,GO:0030509^biological_process^BMP signaling pathway,GO:0070062^cellular_component^extracellular exosome,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0009887^biological_process^animal organ morphogenesis,KEGG:hsa:1954,ENOG410YF0N^Multiple EGF-like-domains 8,.,NA,NA,NA,NA,,
yes,AD,EGF,DN309889_c0_g1_i1,DN309889_c0_g1,EGFR_MACMU,Epidermal growth factor receptor,.,NA,GO:0009925^cellular_component^basal plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005768^cellular_component^endosome,GO:0010008^cellular_component^endosome membrane,.,NA,NA,NA,NA,KEGG:mcc:613027`KO:K04361,ENOG410XNSR^erythroblastic leukemia viral oncogene homolog,.,NA,NA,NA,NA,,
no,AD,EGF,DN303332_c0_g1_i1,DN303332_c0_g1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,.,NA,NA,NA,NA,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",.,NA,NA,NA,NA,,
no,AD,EGF,DN301696_c0_g1_i1,DN301696_c0_g1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,CELR1_MOUSE,Cadherin EGF LAG seven-pass G-type receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005887^cellular_component^integral component of plasma membrane,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:mmu:12614`KO:K04600,"ENOG410XTGH^cadherin, EGF LAG seven-pass G-type receptor",PF00028.17^Cadherin^Cadherin domain^12-65^E:2.3e-11,PF00028.17^Cadherin^Cadherin domain^81-157^E:6e-19,NA,NA,NA,,
no,AD,EGF,DN354776_c0_g1_i1,DN354776_c0_g1,EOGT_CHICK,EGF domain-specific O-linked N-acetylglucosamine transferase,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0016262^molecular_function^protein N-acetylglucosaminyltransferase activity,GO:0006493^biological_process^protein O-linked glycosylation,NA,NA,.,NA,NA,NA,NA,KEGG:gga:426961`KO:K18134,ENOG410ZHQA^glycosyltransferase,.,NA,NA,NA,NA,,
no,AD,EGF,DN439089_c0_g1_i1,DN439089_c0_g1,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,VWDE_HUMAN,von Willebrand factor D and EGF domain-containing protein,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005102^molecular_function^signaling receptor binding,GO:0048856^biological_process^anatomical structure development,NA,KEGG:hsa:221806,ENOG410Z37Q^von Willebrand factor D and EGF,PF12661.7^hEGF^Human growth factor-like EGF^97-115^E:0.0018,PF12661.7^hEGF^Human growth factor-like EGF^129-150^E:0.00022,PF12661.7^hEGF^Human growth factor-like EGF^164-182^E:0.021,NA,NA,,
no,AD,EGF,DN429978_c0_g1_i1,DN429978_c0_g1,MEGF6_RAT,Multiple epidermal growth factor-like domains protein 6,MEGF6_RAT,Multiple epidermal growth factor-like domains protein 6,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,NA,NA,NA,KEGG:rno:65049,ENOG410XQWV^multiple EGF-like-domains,PF00053.24^Laminin_EGF^Laminin EGF domain^65-103^E:0.0019,PF12661.7^hEGF^Human growth factor-like EGF^67-86^E:0.0066,PF00053.24^Laminin_EGF^Laminin EGF domain^108-151^E:0.012,PF00053.24^Laminin_EGF^Laminin EGF domain^151-195^E:0.038,PF00053.24^Laminin_EGF^Laminin EGF domain^193-236^E:0.0041,,
no,AD,EPO,DN9663_c0_g1_i1,DN9663_c0_g1,EPHX4_HUMAN,Epoxide hydrolase 4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:253152`KO:K22369,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN9663_c0_g1_i2,DN9663_c0_g1,EPHX4_HUMAN,Epoxide hydrolase 4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:253152`KO:K22369,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN9663_c0_g2_i1,DN9663_c0_g2,EPHX4_MOUSE,Epoxide hydrolase 4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:384214`KO:K22369,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN83383_c0_g1_i1,DN83383_c0_g1,HYES_PIG,Bifunctional epoxide hydrolase 2,.,NA,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0042577^molecular_function^lipid phosphatase activity,GO:0000287^molecular_function^magnesium ion binding,.,NA,NA,NA,NA,KEGG:ssc:414425`KO:K08726,COG1011^Hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i1,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,PF07884.14^VKOR^Vitamin K epoxide reductase family^6-143^E:1.9e-26,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i2,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,.,NA,NA,NA,NA,KEGG:mmu:27973`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i8,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,PF07884.14^VKOR^Vitamin K epoxide reductase family^6-143^E:1.9e-26,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i9,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,.,NA,NA,NA,NA,KEGG:mmu:27973`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i5,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,.,NA,NA,NA,NA,KEGG:mmu:27973`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN4242_c0_g1_i10,DN4242_c0_g1,VKOR1_MOUSE,Vitamin K epoxide reductase complex subunit 1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0048038^molecular_function^quinone binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,PF07884.14^VKOR^Vitamin K epoxide reductase family^6-143^E:1.9e-26,NA,NA,NA,NA,,
no,AD,EPO,DN63311_c0_g1_i2,DN63311_c0_g1,OPSD_SEPOF,Rhodopsin,OPSD_SEPOF,Rhodopsin,GO:0016021^cellular_component^integral component of membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0009881^molecular_function^photoreceptor activity,GO:0016918^molecular_function^retinal binding,GO:0007602^biological_process^phototransduction,GO:0016021^cellular_component^integral component of membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0009881^molecular_function^photoreceptor activity,GO:0016918^molecular_function^retinal binding,GO:0007602^biological_process^phototransduction,.,.,.,NA,NA,NA,NA,,
no,AD,EPO,DN63311_c0_g1_i1,DN63311_c0_g1,OPSD_SEPOF,Rhodopsin,OPSD_SEPOF,Rhodopsin,GO:0016021^cellular_component^integral component of membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0009881^molecular_function^photoreceptor activity,GO:0016918^molecular_function^retinal binding,GO:0007602^biological_process^phototransduction,GO:0016021^cellular_component^integral component of membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0009881^molecular_function^photoreceptor activity,GO:0016918^molecular_function^retinal binding,GO:0007602^biological_process^phototransduction,.,.,.,NA,NA,NA,NA,,
no,AD,EPO,DN5299_c0_g1_i3,DN5299_c0_g1,RAD50_MOUSE,DNA repair protein RAD50,RAD50_MOUSE,DNA repair protein RAD50,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016234^cellular_component^inclusion body,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016234^cellular_component^inclusion body,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",.,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),.,NA,NA,NA,NA,,
no,AD,EPO,DN5299_c0_g1_i1,DN5299_c0_g1,RAD50_HUMAN,DNA repair protein RAD50,RAD50_HUMAN,DNA repair protein RAD50,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",KEGG:hsa:10111`KO:K10866,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),PF13476.6^AAA_23^AAA domain^6-233^E:6.1e-34,PF13175.6^AAA_15^AAA ATPase domain^24-339^E:3e-10,PF04423.14^Rad50_zn_hook^Rad50 zinc hook motif^660-712^E:8.9e-13,NA,NA,,
no,AD,EPO,DN5299_c0_g1_i4,DN5299_c0_g1,RAD50_HUMAN,DNA repair protein RAD50,RAD50_MOUSE,DNA repair protein RAD50,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016234^cellular_component^inclusion body,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",KEGG:hsa:10111`KO:K10866,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),.,NA,NA,NA,NA,,
no,AD,EPO,DN5299_c0_g1_i5,DN5299_c0_g1,RAD50_MOUSE,DNA repair protein RAD50,RAD50_HUMAN,DNA repair protein RAD50,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016234^cellular_component^inclusion body,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",KEGG:hsa:10111`KO:K10866,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),PF13476.6^AAA_23^AAA domain^6-234^E:1.8e-34,PF13175.6^AAA_15^AAA ATPase domain^24-340^E:2e-08,NA,NA,NA,,
no,AD,EPO,DN5299_c0_g1_i8,DN5299_c0_g1,RAD50_HUMAN,DNA repair protein RAD50,RAD50_HUMAN,DNA repair protein RAD50,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0016020^cellular_component^membrane,GO:0030870^cellular_component^Mre11 complex,GO:0000790^cellular_component^nuclear chromatin,"GO:0000784^cellular_component^nuclear chromosome, telomeric region",KEGG:hsa:10111`KO:K10866,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),PF13476.6^AAA_23^AAA domain^6-233^E:8.9e-34,PF04423.14^Rad50_zn_hook^Rad50 zinc hook motif^660-712^E:1.3e-12,"PF13558.6^SbcCD_C^Putative exonuclease SbcCD, C subunit^1175-1249^E:2.7e-06",NA,NA,,
yes,AD,EPO,DN23904_c0_g1_i2,DN23904_c0_g1,IL1B_CAVPO,Interleukin-1 beta,IL1B_CAVPO,Interleukin-1 beta,GO:0005776^cellular_component^autophagosome,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005764^cellular_component^lysosome,GO:0030141^cellular_component^secretory granule,GO:0005776^cellular_component^autophagosome,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005764^cellular_component^lysosome,GO:0030141^cellular_component^secretory granule,.,"ENOG410XU2E^Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells",PF00340.19^IL1^Interleukin-1 / 18^231-325^E:9.8e-22,NA,NA,NA,NA,,
yes,AD,EPO,DN23904_c0_g1_i8,DN23904_c0_g1,IL1B_CAVPO,Interleukin-1 beta,.,NA,GO:0005776^cellular_component^autophagosome,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005764^cellular_component^lysosome,GO:0030141^cellular_component^secretory granule,.,NA,NA,NA,NA,.,"ENOG410XU2E^Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells",.,NA,NA,NA,NA,,
no,AD,EPO,DN9237_c0_g1_i5,DN9237_c0_g1,COF2_PIG,Cofilin-2,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,.,NA,NA,NA,NA,KEGG:ssc:497233`KO:K05765,ENOG41122P5^actin-depolymerizing factor,.,NA,NA,NA,NA,,
no,AD,EPO,DN9237_c0_g1_i2,DN9237_c0_g1,COF2_CHICK,Cofilin-2,COF2_CHICK,Cofilin-2,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0005634^cellular_component^nucleus,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0005634^cellular_component^nucleus,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,KEGG:gga:423320`KO:K05765,ENOG41122P5^actin-depolymerizing factor,PF00241.20^Cofilin_ADF^Cofilin/tropomyosin-type actin-binding protein^10-129^E:2.1e-33,NA,NA,NA,NA,,
no,AD,EPO,DN9237_c0_g1_i1,DN9237_c0_g1,COF2_CHICK,Cofilin-2,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0005634^cellular_component^nucleus,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,.,NA,NA,NA,NA,KEGG:gga:423320`KO:K05765,ENOG41122P5^actin-depolymerizing factor,.,NA,NA,NA,NA,,
no,AD,EPO,DN9237_c0_g1_i7,DN9237_c0_g1,COF2_CHICK,Cofilin-2,COF2_CHICK,Cofilin-2,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0005634^cellular_component^nucleus,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0016363^cellular_component^nuclear matrix,GO:0005634^cellular_component^nucleus,GO:0030018^cellular_component^Z disc,GO:0051015^molecular_function^actin filament binding,KEGG:gga:423320`KO:K05765,ENOG41122P5^actin-depolymerizing factor,PF00241.20^Cofilin_ADF^Cofilin/tropomyosin-type actin-binding protein^70-148^E:1.1e-15,NA,NA,NA,NA,,
no,AD,EPO,DN8365_c0_g1_i6,DN8365_c0_g1,HYES_HUMAN,Bifunctional epoxide hydrolase 2,HYES_HUMAN,Bifunctional epoxide hydrolase 2,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005782^cellular_component^peroxisomal matrix,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005782^cellular_component^peroxisomal matrix,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,KEGG:hsa:2053`KO:K08726,COG1011^Hydrolase,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^4-110^E:1.8e-14,NA,NA,NA,NA,,
no,AD,EPO,DN8365_c0_g1_i4,DN8365_c0_g1,HYES_HUMAN,Bifunctional epoxide hydrolase 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005782^cellular_component^peroxisomal matrix,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:2053`KO:K08726,COG1011^Hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN8365_c0_g1_i1,DN8365_c0_g1,HYES_PIG,Bifunctional epoxide hydrolase 2,.,NA,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0042577^molecular_function^lipid phosphatase activity,GO:0000287^molecular_function^magnesium ion binding,.,NA,NA,NA,NA,KEGG:ssc:414425`KO:K08726,COG1011^Hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN8365_c0_g1_i3,DN8365_c0_g1,HYES_HUMAN,Bifunctional epoxide hydrolase 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005782^cellular_component^peroxisomal matrix,GO:0005777^cellular_component^peroxisome,GO:0033885^molecular_function^10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:2053`KO:K08726,COG1011^Hydrolase,.,NA,NA,NA,NA,,
yes,AD,EPO,DN36892_c0_g1_i1,DN36892_c0_g1,EPOR_CANLF,Erythropoietin receptor,EPOR_PIG,Erythropoietin receptor,GO:0016021^cellular_component^integral component of membrane,GO:0004896^molecular_function^cytokine receptor activity,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0004900^molecular_function^erythropoietin receptor activity,GO:0042802^molecular_function^identical protein binding,GO:0007420^biological_process^brain development,GO:0046697^biological_process^decidualization,KEGG:ssc:397554`KO:K05079,ENOG4111PGS^erythropoietin receptor,"PF09067.10^EpoR_lig-bind^Erythropoietin receptor, ligand binding^38-139^E:4.1e-18",PF00041.21^fn3^Fibronectin type III domain^146-223^E:4.2e-06,NA,NA,NA,,
yes,AD,EPO,DN36892_c0_g1_i3,DN36892_c0_g1,EPOR_PIG,Erythropoietin receptor,EPOR_PIG,Erythropoietin receptor,GO:0016021^cellular_component^integral component of membrane,GO:0004900^molecular_function^erythropoietin receptor activity,GO:0042802^molecular_function^identical protein binding,GO:0007420^biological_process^brain development,GO:0046697^biological_process^decidualization,GO:0016021^cellular_component^integral component of membrane,GO:0004900^molecular_function^erythropoietin receptor activity,GO:0042802^molecular_function^identical protein binding,GO:0007420^biological_process^brain development,GO:0046697^biological_process^decidualization,KEGG:ssc:397554`KO:K05079,ENOG4111PGS^erythropoietin receptor,"PF09067.10^EpoR_lig-bind^Erythropoietin receptor, ligand binding^38-139^E:1.8e-18",NA,NA,NA,NA,,
no,AD,EPO,DN11468_c0_g3_i2,DN11468_c0_g3,LAMA2_MOUSE,Laminin subunit alpha-2,.,NA,GO:0005604^cellular_component^basement membrane,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0043197^cellular_component^dendritic spine,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:mmu:16773`KO:K05637,COG0419^Involved in DNA double-strand break repair (DSBR). The Rad50 Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and or repositioning DNA ends into the Mre11 active site (By similarity),.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i1,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,"PF00400.32^WD40^WD domain, G-beta repeat^137-171^E:6.9e-06","PF00400.32^WD40^WD domain, G-beta repeat^185-216^E:1.1e-05","PF00400.32^WD40^WD domain, G-beta repeat^265-304^E:0.00018",NA,NA,,
no,AD,EPO,DN2811_c0_g1_i4,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,"PF00400.32^WD40^WD domain, G-beta repeat^54-86^E:0.21","PF00400.32^WD40^WD domain, G-beta repeat^183-217^E:3.9e-06","PF00400.32^WD40^WD domain, G-beta repeat^231-262^E:6.3e-06",NA,NA,,
no,AD,EPO,DN2811_c0_g1_i8,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i11,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i10,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,.,NA,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,.,NA,NA,NA,NA,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i7,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i3,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,.,NA,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,.,NA,NA,NA,NA,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i2,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN2811_c0_g1_i9,DN2811_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,WDR1_CHICK,WD repeat-containing protein 1,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN24447_c0_g1_i10,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^99-217^E:3.5e-17,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^102-364^E:1.2e-26,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^124-208^E:2.2e-07",NA,NA,,
no,AD,EPO,DN24447_c0_g1_i9,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^99-217^E:3.5e-17,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^102-364^E:1.2e-26,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^124-208^E:2.2e-07",NA,NA,,
no,AD,EPO,DN24447_c0_g1_i3,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN24447_c0_g1_i4,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN24447_c0_g1_i5,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^99-217^E:3.5e-17,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^102-364^E:1.2e-26,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^124-208^E:2.2e-07",NA,NA,,
no,AD,EPO,DN24447_c0_g1_i6,DN24447_c0_g1,EPHX3_XENTR,Epoxide hydrolase 3,EPHX3_XENTR,Epoxide hydrolase 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0031090^cellular_component^organelle membrane,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0006629^biological_process^lipid metabolic process,KEGG:xtr:779884`KO:K22368,ENOG410XRPK^hydrolase,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^99-217^E:3.5e-17,PF12697.7^Abhydrolase_6^Alpha/beta hydrolase family^102-364^E:1.2e-26,"PF12146.8^Hydrolase_4^Serine aminopeptidase, S33^124-208^E:2.2e-07",NA,NA,,
no,AD,EPO,DN7279_c0_g1_i3,DN7279_c0_g1,HYEP_RAT,Epoxide hydrolase 1,HYEP_RAT,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,KEGG:rno:25315`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^76-185^E:1.8e-34,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^171-433^E:3.4e-21,NA,NA,NA,,
no,AD,EPO,DN7279_c0_g1_i2,DN7279_c0_g1,HYEP_RAT,Epoxide hydrolase 1,HYEP_RAT,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,KEGG:rno:25315`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^76-185^E:1.4e-34,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^171-401^E:1.2e-20,NA,NA,NA,,
no,AD,EPO,DN7279_c0_g2_i1,DN7279_c0_g2,HYEP_HUMAN,Epoxide hydrolase 1,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0004301^molecular_function^epoxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,.,NA,NA,NA,NA,KEGG:hsa:2052`KO:K01253,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN7279_c0_g3_i1,DN7279_c0_g3,HYEP_PIG,Epoxide hydrolase 1,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,.,NA,NA,NA,NA,KEGG:ssc:397639`KO:K01253,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN69656_c0_g1_i1,DN69656_c0_g1,WDR1_MOUSE,WD repeat-containing protein 1,.,NA,GO:0015629^cellular_component^actin cytoskeleton,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030054^cellular_component^cell junction,GO:0042995^cellular_component^cell projection,GO:0005911^cellular_component^cell-cell junction,.,NA,NA,NA,NA,KEGG:mmu:22388,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN932_c0_g1_i1,DN932_c0_g1,DEST_CHICK,Destrin,DEST_CHICK,Destrin,GO:0015629^cellular_component^actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0051014^biological_process^actin filament severing,GO:0030836^biological_process^positive regulation of actin filament depolymerization,GO:0015629^cellular_component^actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0051014^biological_process^actin filament severing,GO:0030836^biological_process^positive regulation of actin filament depolymerization,KEGG:gga:396539`KO:K10363,ENOG41122P5^actin-depolymerizing factor,PF00241.20^Cofilin_ADF^Cofilin/tropomyosin-type actin-binding protein^27-151^E:2.7e-32,NA,NA,NA,NA,,
no,AD,EPO,DN932_c0_g1_i5,DN932_c0_g1,DEST_CHICK,Destrin,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0051014^biological_process^actin filament severing,GO:0030836^biological_process^positive regulation of actin filament depolymerization,.,NA,NA,NA,NA,KEGG:gga:396539`KO:K10363,ENOG41122P5^actin-depolymerizing factor,.,NA,NA,NA,NA,,
no,AD,EPO,DN7108_c0_g1_i3,DN7108_c0_g1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,PF07884.14^VKOR^Vitamin K epoxide reductase family^29-165^E:1.1e-25,NA,NA,NA,NA,,
no,AD,EPO,DN7108_c0_g1_i1,DN7108_c0_g1,VKORL_RAT,Vitamin K epoxide reductase complex subunit 1-like protein 1,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,GO:0034599^biological_process^cellular response to oxidative stress,.,NA,NA,NA,NA,KEGG:rno:103693015`KEGG:rno:399684`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN7108_c0_g1_i5,DN7108_c0_g1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,.,NA,NA,NA,NA,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN5369_c0_g1_i7,DN5369_c0_g1,HYEP_PIG,Epoxide hydrolase 1,HYEP_PIG,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,KEGG:ssc:397639`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^49-156^E:1.3e-31,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^141-250^E:1.1e-17,NA,NA,NA,,
no,AD,EPO,DN5369_c0_g1_i13,DN5369_c0_g1,HYEP_PIG,Epoxide hydrolase 1,HYEP_PIG,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,KEGG:ssc:397639`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^49-156^E:1.3e-31,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^141-250^E:1.1e-17,NA,NA,NA,,
no,AD,EPO,DN5369_c0_g1_i3,DN5369_c0_g1,HYEP_PIG,Epoxide hydrolase 1,HYEP_PIG,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,KEGG:ssc:397639`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^49-156^E:1.3e-31,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^141-250^E:1.1e-17,NA,NA,NA,,
no,AD,EPO,DN5369_c0_g1_i11,DN5369_c0_g1,HYEP_RABIT,Epoxide hydrolase 1,HYEP_PIG,Epoxide hydrolase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0033961^molecular_function^cis-stilbene-oxide hydrolase activity,GO:0019439^biological_process^aromatic compound catabolic process,GO:0009636^biological_process^response to toxic substance,KEGG:ssc:397639`KO:K01253,COG0596^Alpha beta hydrolase,PF06441.12^EHN^Epoxide hydrolase N terminus^50-157^E:2.6e-31,PF00561.20^Abhydrolase_1^alpha/beta hydrolase fold^142-365^E:2.1e-18,NA,NA,NA,,
no,AD,EPO,DN5369_c0_g2_i1,DN5369_c0_g2,HYEP_MOUSE,Epoxide hydrolase 1,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:mmu:13849`KO:K01253,COG0596^Alpha beta hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN110323_c0_g1_i1,DN110323_c0_g1,WDR1_CHICK,WD repeat-containing protein 1,.,NA,"GO:0042643^cellular_component^actomyosin, actin portion",GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0051015^molecular_function^actin filament binding,GO:0030042^biological_process^actin filament depolymerization,GO:0040011^biological_process^locomotion,.,NA,NA,NA,NA,KEGG:gga:422842,ENOG410XQN1^actin filament depolymerization,.,NA,NA,NA,NA,,
no,AD,EPO,DN107121_c0_g1_i1,DN107121_c0_g1,EPHX4_MOUSE,Epoxide hydrolase 4,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0016787^molecular_function^hydrolase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:384214`KO:K22369,ENOG410XRPK^hydrolase,.,NA,NA,NA,NA,,
no,AD,EPO,DN199807_c0_g1_i2,DN199807_c0_g1,EPOP_HUMAN,Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8},.,NA,GO:0005694^cellular_component^chromosome,GO:0070449^cellular_component^elongin complex,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0003682^molecular_function^chromatin binding,GO:0035616^biological_process^histone H2B conserved C-terminal lysine deubiquitination,.,NA,NA,NA,NA,KEGG:hsa:100170841,ENOG41116AE^SKI DACH domain containing 1,.,NA,NA,NA,NA,,
no,AD,EPO,DN199807_c0_g1_i1,DN199807_c0_g1,EPOP_HUMAN,Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8},EPOP_HUMAN,Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8},GO:0005694^cellular_component^chromosome,GO:0070449^cellular_component^elongin complex,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0003682^molecular_function^chromatin binding,GO:0035616^biological_process^histone H2B conserved C-terminal lysine deubiquitination,GO:0005694^cellular_component^chromosome,GO:0070449^cellular_component^elongin complex,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0003682^molecular_function^chromatin binding,GO:0035616^biological_process^histone H2B conserved C-terminal lysine deubiquitination,KEGG:hsa:100170841,ENOG41116AE^SKI DACH domain containing 1,PF15223.6^EPOP^Elongin BC and Polycomb repressive complex 2-associated protein^245-357^E:2.8e-25,NA,NA,NA,NA,,
no,AD,EPO,DN199807_c0_g1_i3,DN199807_c0_g1,EPOP_HUMAN,Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8},EPOP_HUMAN,Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8},GO:0005694^cellular_component^chromosome,GO:0070449^cellular_component^elongin complex,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0003682^molecular_function^chromatin binding,GO:0035616^biological_process^histone H2B conserved C-terminal lysine deubiquitination,GO:0005694^cellular_component^chromosome,GO:0070449^cellular_component^elongin complex,GO:0035098^cellular_component^ESC/E(Z) complex,GO:0003682^molecular_function^chromatin binding,GO:0035616^biological_process^histone H2B conserved C-terminal lysine deubiquitination,KEGG:hsa:100170841,ENOG41116AE^SKI DACH domain containing 1,PF15223.6^EPOP^Elongin BC and Polycomb repressive complex 2-associated protein^240-352^E:2.7e-25,NA,NA,NA,NA,,
no,AD,EPO,DN215269_c0_g1_i1,DN215269_c0_g1,FAXD_PSEPO,Venom prothrombin activator porpharin-D,FA10_RAT,Coagulation factor X,GO:0005576^cellular_component^extracellular region,GO:0005509^molecular_function^calcium ion binding,GO:0016504^molecular_function^peptidase activator activity,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0090729^molecular_function^toxin activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005615^cellular_component^extracellular space,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005509^molecular_function^calcium ion binding,KEGG:rno:29243`KO:K01314,COG5640^protease,PF00594.20^Gla^Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain^58-97^E:3.2e-19,NA,NA,NA,NA,,
no,AD,EPO,DN222364_c0_g1_i1,DN222364_c0_g1,VKORL_HUMAN,Vitamin K epoxide reductase complex subunit 1-like protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0048038^molecular_function^quinone binding,GO:0047057^molecular_function^vitamin-K-epoxide reductase (warfarin-sensitive) activity,.,NA,NA,NA,NA,KEGG:hsa:154807`KO:K05357,ENOG4111UX7^vitamin K epoxide reductase complex subunit,.,NA,NA,NA,NA,,
no,AD,EPO,DN310110_c0_g1_i1,DN310110_c0_g1,STMD1_HUMAN,Stathmin domain-containing protein 1,STMD1_HUMAN,Stathmin domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0043005^cellular_component^neuron projection,GO:0015631^molecular_function^tubulin binding,GO:0007019^biological_process^microtubule depolymerization,GO:0031175^biological_process^neuron projection development,GO:0005737^cellular_component^cytoplasm,GO:0043005^cellular_component^neuron projection,GO:0015631^molecular_function^tubulin binding,GO:0007019^biological_process^microtubule depolymerization,GO:0031175^biological_process^neuron projection development,KEGG:hsa:401236,ENOG41128DM^regulation of microtubule polymerization or depolymerization,.,NA,NA,NA,NA,,
yes,AD,FGF,DN86_c1_g1_i3,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,.,NA,NA,NA,NA,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN86_c1_g1_i8,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,FGFR3_CHICK,Fibroblast growth factor receptor 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,PF07679.16^I-set^Immunoglobulin I-set domain^129-191^E:7.2e-07,PF00047.25^ig^Immunoglobulin domain^133-196^E:3e-05,PF00047.25^ig^Immunoglobulin domain^238-312^E:8.1e-08,PF07679.16^I-set^Immunoglobulin I-set domain^243-322^E:6.6e-14,PF13927.6^Ig_3^Immunoglobulin domain^243-309^E:2.1e-12,,
yes,AD,FGF,DN86_c1_g1_i4,DN86_c1_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,FGFR2_CHICK,Fibroblast growth factor receptor 2,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,PF00047.25^ig^Immunoglobulin domain^96-170^E:5e-08,PF13927.6^Ig_3^Immunoglobulin domain^99-167^E:3.6e-12,PF13895.6^Ig_2^Immunoglobulin domain^101-171^E:1.1e-10,PF07679.16^I-set^Immunoglobulin I-set domain^104-180^E:9.3e-15,PF07679.16^I-set^Immunoglobulin I-set domain^195-291^E:2.6e-11,,
yes,AD,FGF,DN86_c1_g1_i12,DN86_c1_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,FGFR2_CHICK,Fibroblast growth factor receptor 2,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,PF00047.25^ig^Immunoglobulin domain^96-170^E:5e-08,PF13927.6^Ig_3^Immunoglobulin domain^99-167^E:3.6e-12,PF13895.6^Ig_2^Immunoglobulin domain^101-171^E:1.1e-10,PF07679.16^I-set^Immunoglobulin I-set domain^104-180^E:9.3e-15,PF07679.16^I-set^Immunoglobulin I-set domain^195-289^E:3e-11,,
yes,AD,FGF,DN86_c1_g1_i11,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,FGFR3_CHICK,Fibroblast growth factor receptor 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,PF07679.16^I-set^Immunoglobulin I-set domain^129-191^E:7.2e-07,PF00047.25^ig^Immunoglobulin domain^133-196^E:3e-05,PF00047.25^ig^Immunoglobulin domain^238-312^E:8.1e-08,PF07679.16^I-set^Immunoglobulin I-set domain^243-322^E:6.6e-14,PF13927.6^Ig_3^Immunoglobulin domain^243-309^E:2.1e-12,,
yes,AD,FGF,DN86_c1_g1_i7,DN86_c1_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,FGFR2_CHICK,Fibroblast growth factor receptor 2,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,PF13927.6^Ig_3^Immunoglobulin domain^67-131^E:5.5e-07,PF07679.16^I-set^Immunoglobulin I-set domain^72-142^E:1.1e-05,PF00047.25^ig^Immunoglobulin domain^185-259^E:5.8e-08,PF13927.6^Ig_3^Immunoglobulin domain^188-256^E:4.1e-12,PF13895.6^Ig_2^Immunoglobulin domain^190-260^E:1.3e-10,,
yes,AD,FGF,DN86_c1_g1_i6,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,FGFR3_CHICK,Fibroblast growth factor receptor 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,PF18123.1^FGFR3_TM^Fibroblast growth factor receptor 3 transmembrane domain^6-36^E:5.5e-14,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^109-385^E:1.7e-105,PF00069.25^Pkinase^Protein kinase domain^112-383^E:2.8e-45,NA,NA,,
yes,AD,FGF,DN86_c1_g1_i5,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,FGFR3_CHICK,Fibroblast growth factor receptor 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,PF18123.1^FGFR3_TM^Fibroblast growth factor receptor 3 transmembrane domain^6-36^E:5.5e-14,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^109-385^E:1.7e-105,PF00069.25^Pkinase^Protein kinase domain^112-383^E:2.8e-45,NA,NA,,
yes,AD,FGF,DN86_c1_g1_i10,DN86_c1_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,FGFR3_CHICK,Fibroblast growth factor receptor 3,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,PF18123.1^FGFR3_TM^Fibroblast growth factor receptor 3 transmembrane domain^42-72^E:6.1e-14,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^145-421^E:2.1e-105,PF00069.25^Pkinase^Protein kinase domain^148-419^E:3.5e-45,NA,NA,,
yes,AD,FGF,DN86_c1_g1_i2,DN86_c1_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,FGFR2_CHICK,Fibroblast growth factor receptor 2,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,PF13927.6^Ig_3^Immunoglobulin domain^67-131^E:5.5e-07,PF07679.16^I-set^Immunoglobulin I-set domain^72-142^E:1.1e-05,PF00047.25^ig^Immunoglobulin domain^185-259^E:5.8e-08,PF13927.6^Ig_3^Immunoglobulin domain^188-256^E:4.1e-12,PF13895.6^Ig_2^Immunoglobulin domain^190-260^E:1.3e-10,,
yes,AD,FGF,DN86_c1_g2_i5,DN86_c1_g2,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF13895.6^Ig_2^Immunoglobulin domain^23-122^E:1.6e-06,PF07679.16^I-set^Immunoglobulin I-set domain^30-126^E:1.3e-12,PF13927.6^Ig_3^Immunoglobulin domain^30-113^E:2.1e-12,PF00047.25^ig^Immunoglobulin domain^33-116^E:4.4e-08,PF18123.1^FGFR3_TM^Fibroblast growth factor receptor 3 transmembrane domain^139-168^E:2.1e-14,,
yes,AD,FGF,DN86_c1_g2_i1,DN86_c1_g2,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF13895.6^Ig_2^Immunoglobulin domain^44-116^E:3.2e-06,PF00047.25^ig^Immunoglobulin domain^159-234^E:3.1e-10,PF07679.16^I-set^Immunoglobulin I-set domain^163-241^E:2.5e-14,PF13895.6^Ig_2^Immunoglobulin domain^163-239^E:5.7e-10,PF13927.6^Ig_3^Immunoglobulin domain^164-230^E:4.4e-13,,
yes,AD,FGF,DN86_c1_g2_i3,DN86_c1_g2,FGFR4_COTCO,Fibroblast growth factor receptor 4,FGFR4_PLEWA,Fibroblast growth factor receptor 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,.,PF13895.6^Ig_2^Immunoglobulin domain^44-116^E:3.1e-06,PF00047.25^ig^Immunoglobulin domain^159-234^E:3.1e-10,PF07679.16^I-set^Immunoglobulin I-set domain^163-241^E:2.5e-14,PF13895.6^Ig_2^Immunoglobulin domain^163-239^E:5.7e-10,PF13927.6^Ig_3^Immunoglobulin domain^164-230^E:4.4e-13,,
yes,AD,FGF,DN86_c1_g2_i4,DN86_c1_g2,FGFR4_COTCO,Fibroblast growth factor receptor 4,FGFR4_COTCO,Fibroblast growth factor receptor 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,.,PF13895.6^Ig_2^Immunoglobulin domain^44-116^E:3.5e-06,PF00047.25^ig^Immunoglobulin domain^159-234^E:3.4e-10,PF07679.16^I-set^Immunoglobulin I-set domain^163-241^E:2.7e-14,PF13895.6^Ig_2^Immunoglobulin domain^163-239^E:6.3e-10,PF13927.6^Ig_3^Immunoglobulin domain^164-230^E:4.9e-13,,
yes,AD,FGF,DN86_c1_g2_i2,DN86_c1_g2,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF18123.1^FGFR3_TM^Fibroblast growth factor receptor 3 transmembrane domain^49-78^E:1.9e-14,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^157-432^E:1.8e-105,PF00069.25^Pkinase^Protein kinase domain^159-430^E:6.4e-46,NA,NA,,
yes,AD,FGF,DN28399_c0_g1_i1,DN28399_c0_g1,FGFP2_CHICK,Fibroblast growth factor-binding protein 2,FGFP2_CHICK,Fibroblast growth factor-binding protein 2,GO:0005615^cellular_component^extracellular space,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,NA,KEGG:gga:395094,ENOG4111Z5F^fibroblast growth factor binding protein 2,PF06473.12^FGF-BP1^FGF binding protein 1 (FGF-BP1)^20-208^E:4.2e-53,NA,NA,NA,NA,,
yes,AD,FGF,DN28399_c0_g1_i2,DN28399_c0_g1,FGFP2_CHICK,Fibroblast growth factor-binding protein 2,FGFP2_CHICK,Fibroblast growth factor-binding protein 2,GO:0005615^cellular_component^extracellular space,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,NA,KEGG:gga:395094,ENOG4111Z5F^fibroblast growth factor binding protein 2,PF06473.12^FGF-BP1^FGF binding protein 1 (FGF-BP1)^20-208^E:4.2e-53,NA,NA,NA,NA,,
yes,AD,FGF,DN12024_c0_g1_i1,DN12024_c0_g1,FGFR3_PLEWA,Fibroblast growth factor receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005007^molecular_function^fibroblast growth factor-activated receptor activity,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN44866_c0_g2_i1,DN44866_c0_g2,FGF5_RAT,Fibroblast growth factor 5,FGF5_CANLF,Fibroblast growth factor 5,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005163^molecular_function^nerve growth factor receptor binding,GO:0008283^biological_process^cell population proliferation,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0051781^biological_process^positive regulation of cell division,KEGG:cfa:608459`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^61-124^E:1.2e-16,NA,NA,NA,NA,,
yes,AD,FGF,DN44866_c0_g2_i2,DN44866_c0_g2,FGF5_RAT,Fibroblast growth factor 5,FGF5_CANLF,Fibroblast growth factor 5,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005163^molecular_function^nerve growth factor receptor binding,GO:0008283^biological_process^cell population proliferation,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0051781^biological_process^positive regulation of cell division,KEGG:cfa:608459`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^37-100^E:9.4e-17,NA,NA,NA,NA,,
yes,AD,FGF,DN3662_c0_g1_i3,DN3662_c0_g1,FGF9_HUMAN,Fibroblast growth factor 9,.,NA,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,.,NA,NA,NA,NA,KEGG:hsa:2254`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN3662_c0_g1_i1,DN3662_c0_g1,FGF9_RAT,Fibroblast growth factor 9,FGF9_RAT,Fibroblast growth factor 9,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:rno:25444`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^40-134^E:2e-33,NA,NA,NA,NA,,
yes,AD,FGF,DN3662_c0_g1_i2,DN3662_c0_g1,FGF9_HUMAN,Fibroblast growth factor 9,FGF9_HUMAN,Fibroblast growth factor 9,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,KEGG:hsa:2254`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^62-188^E:2.3e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i2,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,.,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,.,NA,NA,NA,NA,KEGG:mcf:101865789`KO:K16546,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i17,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_MACFA,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,KEGG:mcf:101865789`KO:K16546,.,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^143-223^E:1.9e-28,PF16045.5^LisH_2^LisH^164-187^E:6.6e-07,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i3,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_HUMAN,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,KEGG:hsa:11116`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i7,DN2780_c0_g1,FR1OP_BOVIN,FGFR1 oncogene partner,.,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,.,NA,NA,NA,NA,KEGG:bta:506246`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i6,DN2780_c0_g1,.,NA,FR1OP_HUMAN,FGFR1 oncogene partner,.,NA,NA,NA,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,KEGG:hsa:11116`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i10,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_HUMAN,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,KEGG:hsa:11116`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i9,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_HUMAN,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,KEGG:hsa:11116`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i5,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_MACFA,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,KEGG:mcf:101865789`KO:K16546,.,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^143-223^E:2e-28,PF16045.5^LisH_2^LisH^164-187^E:6.9e-07,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i8,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,.,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,.,NA,NA,NA,NA,KEGG:mcf:101865789`KO:K16546,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i12,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_BOVIN,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,KEGG:bta:506246`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i13,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_BOVIN,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,KEGG:bta:506246`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^143-223^E:2.6e-28,PF16045.5^LisH_2^LisH^164-187^E:8.4e-07,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g1_i4,DN2780_c0_g1,FR1OP_MACFA,FGFR1 oncogene partner,FR1OP_MACFA,FGFR1 oncogene partner,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,KEGG:mcf:101865789`KO:K16546,.,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^143-223^E:1.5e-28,PF16045.5^LisH_2^LisH^164-187^E:5.6e-07,NA,NA,NA,,
yes,AD,FGF,DN2780_c0_g2_i1,DN2780_c0_g2,FR1OP_BOVIN,FGFR1 oncogene partner,.,NA,GO:0042995^cellular_component^cell projection,GO:0005814^cellular_component^centriole,GO:0030030^biological_process^cell projection organization,GO:0034453^biological_process^microtubule anchoring,NA,.,NA,NA,NA,NA,KEGG:bta:506246`KO:K16546,ENOG4111J6Y^FGFR1 oncogene partner,.,NA,NA,NA,NA,,
yes,AD,FGF,DN7680_c0_g1_i4,DN7680_c0_g1,FGF12_RAT,Fibroblast growth factor 12,FGF12_RAT,Fibroblast growth factor 12,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,KEGG:rno:170630`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^13-136^E:1.7e-40,NA,NA,NA,NA,,
yes,AD,FGF,DN7680_c0_g1_i5,DN7680_c0_g1,FGF12_RAT,Fibroblast growth factor 12,FGF12_RAT,Fibroblast growth factor 12,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,KEGG:rno:170630`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^75-198^E:4e-40,NA,NA,NA,NA,,
yes,AD,FGF,DN7680_c0_g1_i7,DN7680_c0_g1,FGF12_RAT,Fibroblast growth factor 12,FGF12_RAT,Fibroblast growth factor 12,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,KEGG:rno:170630`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^75-152^E:3.1e-19,NA,NA,NA,NA,,
yes,AD,FGF,DN7680_c0_g1_i2,DN7680_c0_g1,FGF12_RAT,Fibroblast growth factor 12,FGF12_RAT,Fibroblast growth factor 12,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,KEGG:rno:170630`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^13-90^E:8e-20,NA,NA,NA,NA,,
yes,AD,FGF,DN7680_c0_g1_i8,DN7680_c0_g1,FGF12_RAT,Fibroblast growth factor 12,FGF12_RAT,Fibroblast growth factor 12,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0044325^molecular_function^ion channel binding,GO:0017080^molecular_function^sodium channel regulator activity,GO:0008344^biological_process^adult locomotory behavior,KEGG:rno:170630`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^13-136^E:1.7e-40,NA,NA,NA,NA,,
no,AD,FGF,DN7663_c0_g1_i10,DN7663_c0_g1,TF3C2_HUMAN,General transcription factor 3C polypeptide 2,TF3C2_MOUSE,General transcription factor 3C polypeptide 2,GO:0005654^cellular_component^nucleoplasm,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0042791^biological_process^5S class rRNA transcription by RNA polymerase III,GO:0006383^biological_process^transcription by RNA polymerase III,GO:0042797^biological_process^tRNA transcription by RNA polymerase III,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0006383^biological_process^transcription by RNA polymerase III,NA,NA,NA,KEGG:mmu:71752`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa","PF00400.32^WD40^WD domain, G-beta repeat^548-584^E:0.025",NA,NA,NA,NA,,
no,AD,FGF,DN7663_c0_g1_i3,DN7663_c0_g1,TF3C2_HUMAN,General transcription factor 3C polypeptide 2,TF3C2_HUMAN,General transcription factor 3C polypeptide 2,GO:0005654^cellular_component^nucleoplasm,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0042791^biological_process^5S class rRNA transcription by RNA polymerase III,GO:0006383^biological_process^transcription by RNA polymerase III,GO:0042797^biological_process^tRNA transcription by RNA polymerase III,GO:0005654^cellular_component^nucleoplasm,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0042791^biological_process^5S class rRNA transcription by RNA polymerase III,GO:0006383^biological_process^transcription by RNA polymerase III,GO:0042797^biological_process^tRNA transcription by RNA polymerase III,KEGG:hsa:2976`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa","PF00400.32^WD40^WD domain, G-beta repeat^307-343^E:0.016",NA,NA,NA,NA,,
no,AD,FGF,DN7663_c0_g1_i4,DN7663_c0_g1,TF3C2_MOUSE,General transcription factor 3C polypeptide 2,TF3C2_MOUSE,General transcription factor 3C polypeptide 2,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0006383^biological_process^transcription by RNA polymerase III,NA,NA,NA,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0006383^biological_process^transcription by RNA polymerase III,NA,NA,NA,KEGG:mmu:71752`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa",.,NA,NA,NA,NA,,
no,AD,FGF,DN7663_c0_g1_i1,DN7663_c0_g1,TF3C2_PONAB,General transcription factor 3C polypeptide 2,TF3C2_PONAB,General transcription factor 3C polypeptide 2,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,KEGG:pon:100174311`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa",.,NA,NA,NA,NA,,
no,AD,FGF,DN7663_c0_g1_i8,DN7663_c0_g1,TF3C2_HUMAN,General transcription factor 3C polypeptide 2,TF3C2_HUMAN,General transcription factor 3C polypeptide 2,GO:0005654^cellular_component^nucleoplasm,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0042791^biological_process^5S class rRNA transcription by RNA polymerase III,GO:0006383^biological_process^transcription by RNA polymerase III,GO:0042797^biological_process^tRNA transcription by RNA polymerase III,GO:0005654^cellular_component^nucleoplasm,GO:0000127^cellular_component^transcription factor TFIIIC complex,GO:0042791^biological_process^5S class rRNA transcription by RNA polymerase III,GO:0006383^biological_process^transcription by RNA polymerase III,GO:0042797^biological_process^tRNA transcription by RNA polymerase III,KEGG:hsa:2976`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa",.,NA,NA,NA,NA,,
yes,AD,FGF,DN40554_c0_g1_i2,DN40554_c0_g1,FGF13_RAT,Fibroblast growth factor 13,FGF13_RAT,Fibroblast growth factor 13,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,KEGG:rno:84488`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^81-205^E:2e-43,NA,NA,NA,NA,,
yes,AD,FGF,DN40554_c0_g1_i3,DN40554_c0_g1,FGF13_RAT,Fibroblast growth factor 13,FGF13_RAT,Fibroblast growth factor 13,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,KEGG:rno:84488`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^25-149^E:1e-43,NA,NA,NA,NA,,
yes,AD,FGF,DN40554_c0_g1_i4,DN40554_c0_g1,FGF13_RAT,Fibroblast growth factor 13,FGF13_RAT,Fibroblast growth factor 13,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0005576^cellular_component^extracellular region,KEGG:rno:84488`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^71-195^E:1.8e-43,NA,NA,NA,NA,,
yes,AD,FGF,DN71517_c0_g1_i5,DN71517_c0_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN17338_c0_g1_i1,DN17338_c0_g1,FGF16_HUMAN,Fibroblast growth factor 16,FGF16_HUMAN,Fibroblast growth factor 16,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009887^biological_process^animal organ morphogenesis,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009887^biological_process^animal organ morphogenesis,KEGG:hsa:8823`KO:K04358,.,PF00167.18^FGF^Fibroblast growth factor^93-219^E:1.1e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN49203_c0_g1_i3,DN49203_c0_g1,FGF14_RAT,Fibroblast growth factor 14,FGF14_RAT,Fibroblast growth factor 14,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0007399^biological_process^nervous system development,GO:1901843^biological_process^positive regulation of high voltage-gated calcium channel activity,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0007399^biological_process^nervous system development,GO:1901843^biological_process^positive regulation of high voltage-gated calcium channel activity,KEGG:rno:63851`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^1-113^E:1.3e-33,NA,NA,NA,NA,,
yes,AD,FGF,DN49203_c0_g1_i1,DN49203_c0_g1,FGF14_MOUSE,Fibroblast growth factor 14,FGF14_MOUSE,Fibroblast growth factor 14,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,KEGG:mmu:14169`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^78-202^E:1.9e-40,NA,NA,NA,NA,,
yes,AD,FGF,DN49203_c0_g1_i2,DN49203_c0_g1,FGF14_MOUSE,Fibroblast growth factor 14,FGF14_RAT,Fibroblast growth factor 14,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,GO:0007399^biological_process^nervous system development,GO:1901843^biological_process^positive regulation of high voltage-gated calcium channel activity,KEGG:rno:63851`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^1-113^E:1.3e-33,NA,NA,NA,NA,,
yes,AD,FGF,DN3464_c0_g1_i1,DN3464_c0_g1,FGF2_CHICK,Fibroblast growth factor 2,FGF2_CHICK,Fibroblast growth factor 2,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,KEGG:gga:396413`KO:K18497,.,PF00167.18^FGF^Fibroblast growth factor^64-183^E:1.8e-41,NA,NA,NA,NA,,
yes,AD,FGF,DN57380_c0_g1_i1,DN57380_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i6,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,PF05769.11^SIKE^SIKE family^2-182^E:1.1e-73,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i3,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,PF05769.11^SIKE^SIKE family^2-182^E:1.1e-73,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i4,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,PF05769.11^SIKE^SIKE family^4-184^E:1.1e-73,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i1,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,PF05769.11^SIKE^SIKE family^2-182^E:1.1e-73,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i5,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,.,NA,NA,NA,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,.,NA,NA,NA,NA,,
yes,AD,FGF,DN2568_c0_g1_i2,DN2568_c0_g1,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,FGOP2_CHICK,FGFR1 oncogene partner 2 homolog,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,GO:0005737^cellular_component^cytoplasm,GO:0042803^molecular_function^protein homodimerization activity,GO:0009611^biological_process^response to wounding,GO:0042060^biological_process^wound healing,NA,KEGG:gga:418214,ENOG410XS48^FGFR1 oncogene partner 2,PF05769.11^SIKE^SIKE family^2-182^E:1.1e-73,NA,NA,NA,NA,,
yes,AD,FGF,DN31117_c0_g1_i2,DN31117_c0_g1,FGFR2_DANRE,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN31117_c0_g1_i1,DN31117_c0_g1,FGFR2_DANRE,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN20602_c0_g1_i3,DN20602_c0_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN35058_c0_g1_i5,DN35058_c0_g1,FGFR2_NOTVI,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN35058_c0_g1_i1,DN35058_c0_g1,FGFR2_NOTVI,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN22793_c1_g1_i6,DN22793_c1_g1,FGFR2_HUMAN,Fibroblast growth factor receptor 2,.,NA,GO:0005938^cellular_component^cell cortex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0060076^cellular_component^excitatory synapse,.,NA,NA,NA,NA,KEGG:hsa:2263`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN7231_c0_g1_i1,DN7231_c0_g1,FGFR1_PLEWA,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0016021^cellular_component^integral component of membrane,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN24098_c0_g1_i1,DN24098_c0_g1,FGFR4_COTCO,Fibroblast growth factor receptor 4,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN24098_c0_g1_i2,DN24098_c0_g1,FGFR4_COTCO,Fibroblast growth factor receptor 4,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN24082_c0_g1_i1,DN24082_c0_g1,FGF11_MOUSE,Fibroblast growth factor 11,FGF11_MOUSE,Fibroblast growth factor 11,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,KEGG:mmu:14166`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^39-134^E:4.9e-25,NA,NA,NA,NA,,
yes,AD,FGF,DN24082_c0_g1_i5,DN24082_c0_g1,FGF11_MOUSE,Fibroblast growth factor 11,FGF11_MOUSE,Fibroblast growth factor 11,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,KEGG:mmu:14166`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^15-110^E:3.3e-25,NA,NA,NA,NA,,
yes,AD,FGF,DN24082_c0_g1_i3,DN24082_c0_g1,FGF11_MOUSE,Fibroblast growth factor 11,FGF11_MOUSE,Fibroblast growth factor 11,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0008083^molecular_function^growth factor activity,NA,NA,KEGG:mmu:14166`KO:K22413,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^25-149^E:3.9e-32,NA,NA,NA,NA,,
yes,AD,FGF,DN4852_c0_g1_i10,DN4852_c0_g1,FGF1_CHICK,Fibroblast growth factor 1,FGF1_CHICK,Fibroblast growth factor 1,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,KEGG:gga:396094`KO:K18496,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^28-148^E:3.1e-41,NA,NA,NA,NA,,
yes,AD,FGF,DN4852_c0_g1_i5,DN4852_c0_g1,FGF1_CHICK,Fibroblast growth factor 1,FGF1_CHICK,Fibroblast growth factor 1,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,KEGG:gga:396094`KO:K18496,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^28-148^E:3.1e-41,NA,NA,NA,NA,,
yes,AD,FGF,DN4852_c0_g1_i1,DN4852_c0_g1,FGF1_CHICK,Fibroblast growth factor 1,FGF1_CHICK,Fibroblast growth factor 1,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,KEGG:gga:396094`KO:K18496,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^28-148^E:3.1e-41,NA,NA,NA,NA,,
yes,AD,FGF,DN4852_c0_g1_i2,DN4852_c0_g1,FGF1_CHICK,Fibroblast growth factor 1,FGF1_CHICK,Fibroblast growth factor 1,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005938^cellular_component^cell cortex,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,KEGG:gga:396094`KO:K18496,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^28-148^E:3.1e-41,NA,NA,NA,NA,,
yes,AD,FGF,DN28958_c0_g1_i4,DN28958_c0_g1,FGF4_CHICK,Fibroblast growth factor 4,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0030154^biological_process^cell differentiation,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN28958_c0_g1_i3,DN28958_c0_g1,FGF4_CHICK,Fibroblast growth factor 4,FGF4_CHICK,Fibroblast growth factor 4,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0030154^biological_process^cell differentiation,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0030154^biological_process^cell differentiation,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,.,PF00167.18^FGF^Fibroblast growth factor^104-136^E:0.00022,NA,NA,NA,NA,,
yes,AD,FGF,DN11726_c0_g1_i1,DN11726_c0_g1,FGF19_HUMAN,Fibroblast growth factor 19,FGF19_HUMAN,Fibroblast growth factor 19,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0007507^biological_process^heart development,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0007507^biological_process^heart development,KEGG:hsa:9965`KO:K22603,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^18-120^E:2.1e-24,NA,NA,NA,NA,,
yes,AD,FGF,DN17256_c0_g1_i3,DN17256_c0_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN17256_c0_g1_i1,DN17256_c0_g1,FGFR2_CHICK,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:gga:396259`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN30265_c0_g1_i5,DN30265_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i13,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i3,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,FOPNL_CHICK,LisH domain-containing protein FOPNL,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^70-101^E:8.1e-07,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i14,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,FOPNL_CHICK,LisH domain-containing protein FOPNL,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^70-139^E:4.3e-24,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i6,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i5,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i4,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i10,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i9,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,FOPNL_CHICK,LisH domain-containing protein FOPNL,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^70-101^E:8.1e-07,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i12,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,FOPNL_CHICK,LisH domain-containing protein FOPNL,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,PF09398.10^FOP_dimer^FOP N terminal dimerisation domain^70-101^E:8.1e-07,NA,NA,NA,NA,,
no,AD,FGF,DN4682_c0_g1_i1,DN4682_c0_g1,FOPNL_CHICK,LisH domain-containing protein FOPNL,.,NA,GO:0034451^cellular_component^centriolar satellite,GO:0036064^cellular_component^ciliary basal body,GO:0031514^cellular_component^motile cilium,GO:0060271^biological_process^cilium assembly,GO:0034453^biological_process^microtubule anchoring,.,NA,NA,NA,NA,KEGG:gga:416598`KO:K16535,ENOG4111YXQ^fgfr1op N-terminal like,.,NA,NA,NA,NA,,
yes,AD,FGF,DN61277_c0_g1_i2,DN61277_c0_g1,FGFR4_COTCO,Fibroblast growth factor receptor 4,FGFR4_COTCO,Fibroblast growth factor receptor 4,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,.,PF00047.25^ig^Immunoglobulin domain^8-47^E:4.7e-05,PF13927.6^Ig_3^Immunoglobulin domain^12-45^E:1.9e-07,PF07679.16^I-set^Immunoglobulin I-set domain^12-47^E:3.3e-07,NA,NA,,
yes,AD,FGF,DN9572_c0_g1_i12,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF00047.25^ig^Immunoglobulin domain^61-136^E:3.2e-09,PF13927.6^Ig_3^Immunoglobulin domain^64-132^E:4.3e-11,PF13895.6^Ig_2^Immunoglobulin domain^65-136^E:9.7e-11,PF07679.16^I-set^Immunoglobulin I-set domain^66-145^E:2.2e-14,NA,,
yes,AD,FGF,DN9572_c0_g1_i2,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN9572_c0_g1_i3,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF07679.16^I-set^Immunoglobulin I-set domain^131-214^E:6.2e-07,PF00047.25^ig^Immunoglobulin domain^138-211^E:1.8e-09,PF00047.25^ig^Immunoglobulin domain^258-333^E:1.5e-08,PF13927.6^Ig_3^Immunoglobulin domain^261-329^E:2.1e-10,PF13895.6^Ig_2^Immunoglobulin domain^262-333^E:4.8e-10,,
yes,AD,FGF,DN9572_c0_g1_i13,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN9572_c0_g1_i4,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN9572_c0_g1_i9,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF07679.16^I-set^Immunoglobulin I-set domain^131-214^E:2.2e-07,PF00047.25^ig^Immunoglobulin domain^138-211^E:6.6e-10,NA,NA,NA,,
yes,AD,FGF,DN9572_c0_g1_i7,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF07679.16^I-set^Immunoglobulin I-set domain^132-210^E:1.2e-06,PF00047.25^ig^Immunoglobulin domain^134-207^E:1.7e-09,PF00047.25^ig^Immunoglobulin domain^254-329^E:1.5e-08,PF13927.6^Ig_3^Immunoglobulin domain^257-325^E:2e-10,PF13895.6^Ig_2^Immunoglobulin domain^258-329^E:4.7e-10,,
yes,AD,FGF,DN9572_c0_g1_i11,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,FGFR1_CHICK,Fibroblast growth factor receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,KEGG:gga:396516`KO:K04362,.,PF00047.25^ig^Immunoglobulin domain^170-245^E:9.3e-09,PF13927.6^Ig_3^Immunoglobulin domain^173-241^E:1.2e-10,PF13895.6^Ig_2^Immunoglobulin domain^174-245^E:2.9e-10,PF07679.16^I-set^Immunoglobulin I-set domain^176-254^E:6.4e-14,NA,,
yes,AD,FGF,DN9572_c0_g1_i8,DN9572_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN8672_c0_g1_i2,DN8672_c0_g1,FGFP1_RAT,Fibroblast growth factor-binding protein 1,FGFP1_RAT,Fibroblast growth factor-binding protein 1,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,KEGG:rno:64535,ENOG4111SHY^fibroblast growth factor binding protein 1,PF06473.12^FGF-BP1^FGF binding protein 1 (FGF-BP1)^9-235^E:4.5e-62,NA,NA,NA,NA,,
yes,AD,FGF,DN8672_c0_g1_i1,DN8672_c0_g1,FGFP1_RAT,Fibroblast growth factor-binding protein 1,FGFP1_RAT,Fibroblast growth factor-binding protein 1,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,GO:0005615^cellular_component^extracellular space,GO:0005886^cellular_component^plasma membrane,GO:0019838^molecular_function^growth factor binding,GO:0007267^biological_process^cell-cell signaling,NA,KEGG:rno:64535,ENOG4111SHY^fibroblast growth factor binding protein 1,PF06473.12^FGF-BP1^FGF binding protein 1 (FGF-BP1)^9-235^E:4.5e-62,NA,NA,NA,NA,,
yes,AD,FGF,DN33317_c0_g1_i4,DN33317_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN4994_c0_g1_i2,DN4994_c0_g1,FGF7_PONAB,Fibroblast growth factor 7,FGF7_PONAB,Fibroblast growth factor 7,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,KEGG:pon:100172539`KO:K04358,COG0153^Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity),PF00167.18^FGF^Fibroblast growth factor^65-189^E:8.1e-49,NA,NA,NA,NA,,
yes,AD,FGF,DN4994_c0_g1_i4,DN4994_c0_g1,FGF7_CANLF,Fibroblast growth factor 7,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,GO:0042056^molecular_function^chemoattractant activity,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:cfa:403915`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN4994_c0_g1_i5,DN4994_c0_g1,FGF7_PONAB,Fibroblast growth factor 7,FGF7_PONAB,Fibroblast growth factor 7,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,KEGG:pon:100172539`KO:K04358,COG0153^Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity),PF00167.18^FGF^Fibroblast growth factor^65-189^E:8.1e-49,NA,NA,NA,NA,,
yes,AD,FGF,DN4994_c0_g1_i1,DN4994_c0_g1,FGF7_PONAB,Fibroblast growth factor 7,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,KEGG:pon:100172539`KO:K04358,COG0153^Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity),.,NA,NA,NA,NA,,
yes,AD,FGF,DN4994_c0_g1_i3,DN4994_c0_g1,FGF7_CEREL,Fibroblast growth factor 7,FGF7_CEREL,Fibroblast growth factor 7,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,.,PF00167.18^FGF^Fibroblast growth factor^48-172^E:6.1e-49,NA,NA,NA,NA,,
yes,AD,FGF,DN9835_c0_g1_i2,DN9835_c0_g1,FGFR3_PLEWA,Fibroblast growth factor receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005007^molecular_function^fibroblast growth factor-activated receptor activity,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN9835_c0_g1_i1,DN9835_c0_g1,FGFR3_PLEWA,Fibroblast growth factor receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005007^molecular_function^fibroblast growth factor-activated receptor activity,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN32184_c0_g1_i1,DN32184_c0_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,.,NA,NA,NA,NA,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN47613_c0_g1_i5,DN47613_c0_g1,FGF22_MOUSE,Fibroblast growth factor 22,FGF22_MOUSE,Fibroblast growth factor 22,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:mmu:67112`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^53-112^E:2.9e-17,NA,NA,NA,NA,,
yes,AD,FGF,DN47613_c0_g1_i4,DN47613_c0_g1,FGF22_MOUSE,Fibroblast growth factor 22,FGF22_MOUSE,Fibroblast growth factor 22,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:mmu:67112`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^64-159^E:1.3e-34,NA,NA,NA,NA,,
yes,AD,FGF,DN47613_c0_g1_i2,DN47613_c0_g1,FGF22_MOUSE,Fibroblast growth factor 22,FGF22_MOUSE,Fibroblast growth factor 22,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0009986^cellular_component^cell surface,GO:0005794^cellular_component^Golgi apparatus,GO:0005730^cellular_component^nucleolus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:mmu:67112`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^53-112^E:2.9e-17,NA,NA,NA,NA,,
yes,AD,FGF,DN13236_c1_g1_i4,DN13236_c1_g1,FGF10_HUMAN,Fibroblast growth factor 10,FGF10_HUMAN,Fibroblast growth factor 10,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:2255`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^82-206^E:7.4e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN13236_c1_g1_i3,DN13236_c1_g1,FGF10_HUMAN,Fibroblast growth factor 10,FGF10_HUMAN,Fibroblast growth factor 10,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:2255`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^82-206^E:7.4e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN13236_c1_g1_i2,DN13236_c1_g1,FGF10_HUMAN,Fibroblast growth factor 10,FGF10_HUMAN,Fibroblast growth factor 10,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:2255`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^82-206^E:7.4e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN13236_c1_g1_i1,DN13236_c1_g1,FGF10_HUMAN,Fibroblast growth factor 10,FGF10_HUMAN,Fibroblast growth factor 10,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:2255`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^82-206^E:7.4e-47,NA,NA,NA,NA,,
yes,AD,FGF,DN13236_c1_g4_i1,DN13236_c1_g4,FGF10_HUMAN,Fibroblast growth factor 10,FGF10_RAT,Fibroblast growth factor 10,GO:0009986^cellular_component^cell surface,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0009986^cellular_component^cell surface,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:rno:25443`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^82-114^E:3.3e-05,NA,NA,NA,NA,,
yes,AD,FGF,DN105547_c0_g1_i1,DN105547_c0_g1,FGFR3_PLEWA,Fibroblast growth factor receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005007^molecular_function^fibroblast growth factor-activated receptor activity,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,FGF,DN112646_c0_g1_i1,DN112646_c0_g1,TF3C2_PONAB,General transcription factor 3C polypeptide 2,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100174311`KO:K15200,"ENOG410YFGF^General transcription factor IIIC, polypeptide 2, beta 110kDa",.,NA,NA,NA,NA,,
yes,AD,FGF,DN124720_c0_g1_i1,DN124720_c0_g1,FGF18_HUMAN,Fibroblast growth factor 18,FGF18_HUMAN,Fibroblast growth factor 18,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0008083^molecular_function^growth factor activity,GO:0005105^molecular_function^type 1 fibroblast growth factor receptor binding,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0008083^molecular_function^growth factor activity,GO:0005105^molecular_function^type 1 fibroblast growth factor receptor binding,KEGG:hsa:8817`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^150-272^E:5e-42,NA,NA,NA,NA,,
yes,AD,FGF,DN124720_c0_g1_i2,DN124720_c0_g1,FGF18_HUMAN,Fibroblast growth factor 18,FGF18_HUMAN,Fibroblast growth factor 18,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0008083^molecular_function^growth factor activity,GO:0005105^molecular_function^type 1 fibroblast growth factor receptor binding,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0008083^molecular_function^growth factor activity,GO:0005105^molecular_function^type 1 fibroblast growth factor receptor binding,KEGG:hsa:8817`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^104-226^E:3.4e-42,NA,NA,NA,NA,,
yes,AD,FGF,DN100381_c0_g1_i1,DN100381_c0_g1,FGFR2_NOTVI,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN126997_c0_g1_i1,DN126997_c0_g1,FGF19_HUMAN,Fibroblast growth factor 19,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0007507^biological_process^heart development,.,NA,NA,NA,NA,KEGG:hsa:9965`KO:K22603,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN143217_c0_g1_i1,DN143217_c0_g1,FGFR2_NOTVI,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN100201_c0_g1_i1,DN100201_c0_g1,FGFR3_MOUSE,Fibroblast growth factor receptor 3,.,NA,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN197114_c0_g1_i1,DN197114_c0_g1,FGFR1_CHICK,Fibroblast growth factor receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:gga:396516`KO:K04362,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN162947_c0_g1_i1,DN162947_c0_g1,FGF4_CHICK,Fibroblast growth factor 4,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0030154^biological_process^cell differentiation,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN239616_c0_g1_i1,DN239616_c0_g1,FGFR2_MOUSE,Fibroblast growth factor receptor 2,.,NA,GO:0005938^cellular_component^cell cortex,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0060076^cellular_component^excitatory synapse,.,NA,NA,NA,NA,KEGG:mmu:14183`KO:K05093,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN291946_c0_g1_i1,DN291946_c0_g1,FGF5_RAT,Fibroblast growth factor 5,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005163^molecular_function^nerve growth factor receptor binding,GO:0008283^biological_process^cell population proliferation,.,NA,NA,NA,NA,KEGG:rno:60662`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN232378_c0_g1_i1,DN232378_c0_g1,FGFR3_PLEWA,Fibroblast growth factor receptor 3,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005007^molecular_function^fibroblast growth factor-activated receptor activity,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN266621_c0_g1_i1,DN266621_c0_g1,FGF16_RAT,Fibroblast growth factor 16,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,GO:0070349^biological_process^positive regulation of brown fat cell proliferation,.,NA,NA,NA,NA,KEGG:rno:60464`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN238186_c0_g1_i1,DN238186_c0_g1,FGF8_CHICK,Fibroblast growth factor 8,FGF8_CHICK,Fibroblast growth factor 8,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0051216^biological_process^cartilage development,GO:0030154^biological_process^cell differentiation,GO:0005576^cellular_component^extracellular region,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0051216^biological_process^cartilage development,GO:0030154^biological_process^cell differentiation,KEGG:gga:396313`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,PF00167.18^FGF^Fibroblast growth factor^20-100^E:2.7e-25,NA,NA,NA,NA,,
yes,AD,FGF,DN226261_c0_g1_i2,DN226261_c0_g1,FGFR2_XENLA,Fibroblast growth factor receptor 2,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN350667_c0_g1_i1,DN350667_c0_g1,FGFR4_COTCO,Fibroblast growth factor receptor 4,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN335643_c0_g1_i1,DN335643_c0_g1,FGFR3_CHICK,Fibroblast growth factor receptor 3,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0030133^cellular_component^transport vesicle,.,NA,NA,NA,NA,KEGG:gga:396515`KO:K05094,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN325636_c0_g1_i1,DN325636_c0_g1,FGFR3_HUMAN,Fibroblast growth factor receptor 3,.,NA,GO:0009986^cellular_component^cell surface,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:2261`KO:K05094,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,FGF,DN372011_c0_g1_i1,DN372011_c0_g1,FGF17_RAT,Fibroblast growth factor 17,.,NA,GO:0005576^cellular_component^extracellular region,GO:0008083^molecular_function^growth factor activity,GO:0005105^molecular_function^type 1 fibroblast growth factor receptor binding,GO:0005111^molecular_function^type 2 fibroblast growth factor receptor binding,GO:0008543^biological_process^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,KEGG:rno:29368`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGF,DN434701_c0_g1_i1,DN434701_c0_g1,FGF2_CHICK,Fibroblast growth factor 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005615^cellular_component^extracellular space,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005104^molecular_function^fibroblast growth factor receptor binding,.,NA,NA,NA,NA,KEGG:gga:396413`KO:K18497,.,.,NA,NA,NA,NA,,
yes,AD,FGF,DN415530_c0_g1_i1,DN415530_c0_g1,FGF9_RAT,Fibroblast growth factor 9,.,NA,GO:0005604^cellular_component^basement membrane,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005104^molecular_function^fibroblast growth factor receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:rno:25444`KO:K04358,ENOG4111IPH^fibroblast growth factor receptor signaling pathway,.,NA,NA,NA,NA,,
yes,AD,FGL,DN89948_c0_g1_i1,DN89948_c0_g1,FGL1_HUMAN,Fibrinogen-like protein 1 {ECO:0000303|PubMed:18039467},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005577^cellular_component^fibrinogen complex,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,.,NA,NA,NA,NA,KEGG:hsa:2267,ENOG410ZYS4^fibrinogen,.,NA,NA,NA,NA,,
yes,AD,FGL,DN26478_c0_g1_i1,DN26478_c0_g1,FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},ANGL1_MOUSE,Angiopoietin-related protein 1,GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0005102^molecular_function^signaling receptor binding,GO:0007169^biological_process^transmembrane receptor protein tyrosine kinase signaling pathway,NA,NA,KEGG:mmu:72713,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^2-184^E:6.6e-40",NA,NA,NA,NA,,
yes,AD,FGL,DN26478_c0_g1_i2,DN26478_c0_g1,FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,.,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^49-266^E:2.1e-45",NA,NA,NA,NA,,
yes,AD,FGL,DN2825_c2_g1_i2,DN2825_c2_g1,FGL1_BOVIN,Fibrinogen-like protein 1,FGL1_BOVIN,Fibrinogen-like protein 1,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,KEGG:bta:508090,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^81-305^E:1e-77",NA,NA,NA,NA,,
yes,AD,FGL,DN2825_c2_g1_i1,DN2825_c2_g1,FGL1_BOVIN,Fibrinogen-like protein 1,FGL1_BOVIN,Fibrinogen-like protein 1,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,KEGG:bta:508090,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^6-206^E:2.6e-72",NA,NA,NA,NA,,
yes,AD,FGL,DN6319_c1_g1_i4,DN6319_c1_g1,FGL2_HUMAN,Fibroleukin,FGL2_HUMAN,Fibroleukin,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005577^cellular_component^fibrinogen complex,GO:1904813^cellular_component^ficolin-1-rich granule lumen,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005577^cellular_component^fibrinogen complex,GO:1904813^cellular_component^ficolin-1-rich granule lumen,KEGG:hsa:10875,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^246-471^E:5.9e-88",NA,NA,NA,NA,,
yes,AD,FGL,DN3002_c0_g1_i3,DN3002_c0_g1,FGL1_BOVIN,Fibrinogen-like protein 1,.,NA,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,.,NA,NA,NA,NA,KEGG:bta:508090,ENOG410ZYS4^fibrinogen,.,NA,NA,NA,NA,,
yes,AD,FGL,DN3002_c0_g1_i6,DN3002_c0_g1,FGL1_BOVIN,Fibrinogen-like protein 1,FGL1_BOVIN,Fibrinogen-like protein 1,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,GO:0005576^cellular_component^extracellular region,GO:0002250^biological_process^adaptive immune response,GO:0072574^biological_process^hepatocyte proliferation,GO:0050868^biological_process^negative regulation of T cell activation,GO:0050776^biological_process^regulation of immune response,KEGG:bta:508090,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^95-319^E:2e-74",NA,NA,NA,NA,,
yes,AD,FGL,DN213795_c0_g1_i1,DN213795_c0_g1,FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,.,ENOG410ZYS4^fibrinogen,"PF00147.18^Fibrinogen_C^Fibrinogen beta and gamma chains, C-terminal globular domain^4-130^E:4e-39",NA,NA,NA,NA,,
yes,AD,FGL,DN348960_c0_g1_i1,DN348960_c0_g1,FGL1L_CHICK,Fibrinogen-like protein 1-like protein {ECO:0000305},.,NA,GO:0004126^molecular_function^cytidine deaminase activity,GO:0047844^molecular_function^deoxycytidine deaminase activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG410ZYS4^fibrinogen,.,NA,NA,NA,NA,,
no,AD,GDF,DN3691_c1_g1_i2,DN3691_c1_g1,DERR_XENTR,Derriere protein,GDF3_XENLA,Growth/differentiation factor 3,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0019838^molecular_function^growth factor binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:xla:394305`KO:K22672,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
no,AD,GDF,DN3691_c1_g1_i5,DN3691_c1_g1,DERR_XENTR,Derriere protein,GDF3_XENLA,Growth/differentiation factor 3,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0019838^molecular_function^growth factor binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:xla:394305`KO:K22672,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
no,AD,GDF,DN3691_c1_g1_i15,DN3691_c1_g1,DERR_XENTR,Derriere protein,GDF3_XENLA,Growth/differentiation factor 3,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0019838^molecular_function^growth factor binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:xla:394305`KO:K22672,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
no,AD,GDF,DN3691_c1_g1_i7,DN3691_c1_g1,DERR_XENTR,Derriere protein,GDF3_XENLA,Growth/differentiation factor 3,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0019838^molecular_function^growth factor binding,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:xla:394305`KO:K22672,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,GDF,DN290_c5_g1_i1,DN290_c5_g1,GDF6A_DANRE,Growth/differentiation factor 6-A,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0006915^biological_process^apoptotic process,.,NA,NA,NA,NA,KEGG:dre:566470`KO:K20012,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,GDF,DN290_c5_g1_i2,DN290_c5_g1,GDF6A_DANRE,Growth/differentiation factor 6-A,GDF6_RAT,Growth/differentiation factor 6,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0006915^biological_process^apoptotic process,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,KEGG:rno:252834`KO:K20012,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^50-203^E:6.4e-14,PF00019.20^TGF_beta^Transforming growth factor beta like domain^266-367^E:2.6e-33,NA,NA,NA,,
yes,AD,GDF,DN27162_c0_g1_i51,DN27162_c0_g1,GDF8_ANSAN,Growth/differentiation factor 8,GDF8_ANSAN,Growth/differentiation factor 8,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,.,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^26-108^E:2.1e-12,NA,NA,NA,NA,,
yes,AD,GDF,DN27162_c0_g1_i21,DN27162_c0_g1,GDF8_ANSAN,Growth/differentiation factor 8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,GDF,DN16541_c0_g1_i1,DN16541_c0_g1,GDF15_RAT,Growth/differentiation factor 15,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005634^cellular_component^nucleus,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:rno:29455`KO:K05504,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,GDF,DN3046_c4_g1_i1,DN3046_c4_g1,GDF11_RAT,Growth/differentiation factor 11,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005654^cellular_component^nucleoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:rno:29454`KO:K22679,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,GDF,DN16080_c0_g1_i1,DN16080_c0_g1,GDF6_HUMAN,Growth/differentiation factor 6,GDF6_RAT,Growth/differentiation factor 6,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,KEGG:rno:252834`KO:K20012,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^71-171^E:2.8e-11,NA,NA,NA,NA,,
yes,AD,GDF,DN15234_c0_g1_i2,DN15234_c0_g1,GDF8_SYNCH,Growth/differentiation factor 8,GDF8_ANSAN,Growth/differentiation factor 8,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,.,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^76-158^E:7.2e-12,NA,NA,NA,NA,,
yes,AD,GDF,DN15234_c0_g1_i6,DN15234_c0_g1,GDF8_MELGA,Growth/differentiation factor 8,GDF8_MELGA,Growth/differentiation factor 8,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,KEGG:mgp:100303659`KO:K05497,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^4-109^E:1.2e-15,PF00019.20^TGF_beta^Transforming growth factor beta like domain^150-244^E:1.9e-28,NA,NA,NA,,
yes,AD,GDF,DN15234_c0_g1_i1,DN15234_c0_g1,GDF8_ANAPL,Growth/differentiation factor 8,GDF8_ANAPL,Growth/differentiation factor 8,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,.,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^76-275^E:1.3e-33,PF00019.20^TGF_beta^Transforming growth factor beta like domain^317-411^E:5.4e-28,NA,NA,NA,,
yes,AD,GDF,DN15234_c0_g1_i5,DN15234_c0_g1,GDF8_MELGA,Growth/differentiation factor 8,GDF8_ANSAN,Growth/differentiation factor 8,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0033002^biological_process^muscle cell proliferation,GO:2000818^biological_process^negative regulation of myoblast proliferation,KEGG:mgp:100303659`KO:K05497,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^76-158^E:6.1e-12,NA,NA,NA,NA,,
yes,AD,GDF,DN15234_c0_g1_i7,DN15234_c0_g1,GDF8_CHICK,Growth/differentiation factor 8,.,NA,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0008201^molecular_function^heparin binding,.,NA,NA,NA,NA,KEGG:gga:373964`KO:K05497,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,GDF,DN32455_c2_g1_i1,DN32455_c2_g1,GDF11_HUMAN,Growth/differentiation factor 11 {ECO:0000303|PubMed:10391213},GDF11_RAT,Growth/differentiation factor 11,GO:0005615^cellular_component^extracellular space,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005125^molecular_function^cytokine activity,GO:0005615^cellular_component^extracellular space,GO:0005654^cellular_component^nucleoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,KEGG:rno:29454`KO:K22679,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^58-123^E:2.6e-13,NA,NA,NA,NA,,
yes,AD,GDF,DN70926_c0_g1_i1,DN70926_c0_g1,GDF9_PAPAN,Growth/differentiation factor 9,GDF9_SHEEP,Growth/differentiation factor 9,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,NA,NA,KEGG:oas:100217402`KO:K22673,.,.,NA,NA,NA,NA,,
yes,AD,GDF,DN18272_c0_g1_i1,DN18272_c0_g1,GDF10_MOUSE,Growth/differentiation factor 10,GDF10_MOUSE,Growth/differentiation factor 10,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0048468^biological_process^cell development,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005160^molecular_function^transforming growth factor beta receptor binding,GO:0048468^biological_process^cell development,KEGG:mmu:14560`KO:K22674,ENOG410XT8Z^bone morphogenetic protein,PF00019.20^TGF_beta^Transforming growth factor beta like domain^353-454^E:7.2e-30,NA,NA,NA,NA,,
yes,AD,GDF,DN239999_c0_g1_i1,DN239999_c0_g1,GDF9_PAPAN,Growth/differentiation factor 9,GDF9_PAPAN,Growth/differentiation factor 9,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i8,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^261-300^E:2.1e-13,PF00051.18^Kringle^Kringle domain^313-391^E:4e-29,PF00051.18^Kringle^Kringle domain^400-478^E:1.6e-28,PF00089.26^Trypsin^Trypsin^515-676^E:2.3e-24,NA,,
yes,AD,HGF,DN5240_c0_g1_i16,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00024.26^PAN_1^PAN domain^58-110^E:2.7e-10,PF14295.6^PAN_4^PAN domain^58-85^E:0.025,PF00051.18^Kringle^Kringle domain^115-151^E:1.2e-07,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i9,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_BOVIN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,KEGG:bta:514667`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^28-76^E:2.4e-14,PF00051.18^Kringle^Kringle domain^81-120^E:3.8e-10,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i10,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^31-76^E:1.2e-13,PF00051.18^Kringle^Kringle domain^81-158^E:2e-28,PF00051.18^Kringle^Kringle domain^171-249^E:2.9e-29,PF00051.18^Kringle^Kringle domain^258-336^E:1.2e-28,PF00089.26^Trypsin^Trypsin^373-534^E:1.5e-24,,
yes,AD,HGF,DN5240_c0_g1_i7,DN5240_c0_g1,HGFL_BOVIN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^106-150^E:2.7e-15,PF00089.26^Trypsin^Trypsin^187-225^E:2.7e-08,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i2,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00024.26^PAN_1^PAN domain^58-110^E:2e-09,PF14295.6^PAN_4^PAN domain^58-85^E:0.15,PF00051.18^Kringle^Kringle domain^115-191^E:1.2e-24,PF00051.18^Kringle^Kringle domain^196-273^E:2.7e-28,PF00051.18^Kringle^Kringle domain^286-364^E:3.8e-29,,
yes,AD,HGF,DN5240_c0_g1_i6,DN5240_c0_g1,HGFL_BOVIN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^1-36^E:3.2e-12,PF00051.18^Kringle^Kringle domain^45-123^E:1.9e-29,PF00089.26^Trypsin^Trypsin^160-198^E:2.2e-08,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i5,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^27-66^E:5.9e-14,PF00051.18^Kringle^Kringle domain^79-157^E:9.3e-30,PF00051.18^Kringle^Kringle domain^166-244^E:3.7e-29,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i13,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^261-300^E:2.4e-13,PF00051.18^Kringle^Kringle domain^313-391^E:4.7e-29,PF00051.18^Kringle^Kringle domain^400-478^E:1.9e-28,PF00089.26^Trypsin^Trypsin^515-641^E:4.9e-18,NA,,
yes,AD,HGF,DN5240_c0_g1_i14,DN5240_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,HGFL_BOVIN,Hepatocyte growth factor-like protein,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,KEGG:bta:514667`KO:K23441,COG5640^protease,PF00089.26^Trypsin^Trypsin^52-213^E:1.5e-25,NA,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g1_i1,DN5240_c0_g1,HGFL_BOVIN,Hepatocyte growth factor-like protein,HGFL_HUMAN,Hepatocyte growth factor-like protein,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,KEGG:hsa:4485`KO:K23441,COG5640^protease,PF00051.18^Kringle^Kringle domain^76-118^E:5.9e-14,PF00051.18^Kringle^Kringle domain^127-157^E:1.5e-08,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g2_i1,DN5240_c0_g2,HGFL_BOVIN,Hepatocyte growth factor-like protein,HGFL_BOVIN,Hepatocyte growth factor-like protein,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,KEGG:bta:514667`KO:K23441,COG5640^protease,PF00089.26^Trypsin^Trypsin^5-93^E:4e-17,NA,NA,NA,NA,,
yes,AD,HGF,DN5240_c0_g2_i2,DN5240_c0_g2,HGFL_MOUSE,Hepatocyte growth factor-like protein,HGFL_BOVIN,Hepatocyte growth factor-like protein,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005773^cellular_component^vacuole,GO:0019899^molecular_function^enzyme binding,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0045721^biological_process^negative regulation of gluconeogenesis,GO:0033601^biological_process^positive regulation of mammary gland epithelial cell proliferation,KEGG:bta:514667`KO:K23441,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN64715_c0_g1_i1,DN64715_c0_g1,HGFL_HUMAN,Hepatocyte growth factor-like protein,.,NA,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030971^molecular_function^receptor tyrosine kinase binding,GO:0004252^molecular_function^serine-type endopeptidase activity,.,NA,NA,NA,NA,KEGG:hsa:4485`KO:K23441,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN12277_c0_g1_i4,DN12277_c0_g1,HGF_CANLF,Hepatocyte growth factor,.,NA,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,.,NA,NA,NA,NA,KEGG:cfa:403441`KO:K05460,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN12277_c0_g1_i7,DN12277_c0_g1,HGF_FELCA,Hepatocyte growth factor,HGF_FELCA,Hepatocyte growth factor,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,KEGG:fca:493705`KO:K05460,COG5640^protease,PF00024.26^PAN_1^PAN domain^59-117^E:1.2e-09,PF00051.18^Kringle^Kringle domain^124-202^E:6.9e-28,PF00051.18^Kringle^Kringle domain^207-284^E:2.3e-28,PF00051.18^Kringle^Kringle domain^301-379^E:1e-29,PF00051.18^Kringle^Kringle domain^387-467^E:3.7e-24,,
yes,AD,HGF,DN12277_c0_g1_i2,DN12277_c0_g1,HGF_BOVIN,Hepatocyte growth factor,HGF_BOVIN,Hepatocyte growth factor,GO:0008083^molecular_function^growth factor activity,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,GO:0048012^biological_process^hepatocyte growth factor receptor signaling pathway,GO:0043066^biological_process^negative regulation of apoptotic process,GO:0008083^molecular_function^growth factor activity,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,GO:0048012^biological_process^hepatocyte growth factor receptor signaling pathway,GO:0043066^biological_process^negative regulation of apoptotic process,KEGG:bta:282879`KO:K05460,COG5640^protease,PF00051.18^Kringle^Kringle domain^13-91^E:7.3e-30,PF00051.18^Kringle^Kringle domain^99-179^E:2.7e-24,PF00089.26^Trypsin^Trypsin^206-428^E:4.9e-48,NA,NA,,
yes,AD,HGF,DN12277_c0_g1_i5,DN12277_c0_g1,HGF_FELCA,Hepatocyte growth factor,.,NA,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,.,NA,NA,NA,NA,KEGG:fca:493705`KO:K05460,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN12277_c0_g1_i8,DN12277_c0_g1,HGF_CANLF,Hepatocyte growth factor,HGF_HUMAN,Hepatocyte growth factor,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,KEGG:hsa:3082`KO:K05460,COG5640^protease,PF00089.26^Trypsin^Trypsin^21-109^E:1.1e-17,NA,NA,NA,NA,,
yes,AD,HGF,DN12277_c0_g1_i10,DN12277_c0_g1,HGF_CANLF,Hepatocyte growth factor,HGF_BOVIN,Hepatocyte growth factor,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,GO:0008083^molecular_function^growth factor activity,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,GO:0048012^biological_process^hepatocyte growth factor receptor signaling pathway,GO:0043066^biological_process^negative regulation of apoptotic process,KEGG:bta:282879`KO:K05460,COG5640^protease,PF00024.26^PAN_1^PAN domain^59-117^E:1.8e-09,PF00051.18^Kringle^Kringle domain^124-202^E:1.1e-27,PF00051.18^Kringle^Kringle domain^207-284^E:3.5e-28,PF00051.18^Kringle^Kringle domain^301-379^E:1.5e-29,PF00051.18^Kringle^Kringle domain^387-467^E:5.6e-24,,
yes,AD,HGF,DN12277_c0_g1_i3,DN12277_c0_g1,HGF_CANLF,Hepatocyte growth factor,HGF_CANLF,Hepatocyte growth factor,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,KEGG:cfa:403441`KO:K05460,COG5640^protease,PF00024.26^PAN_1^PAN domain^59-117^E:1.7e-09,PF00051.18^Kringle^Kringle domain^124-202^E:9.9e-28,PF00051.18^Kringle^Kringle domain^207-284^E:3.2e-28,PF00051.18^Kringle^Kringle domain^301-379^E:1.4e-29,PF00051.18^Kringle^Kringle domain^387-467^E:5.3e-24,,
yes,AD,HGF,DN12277_c0_g1_i9,DN12277_c0_g1,HGF_CANLF,Hepatocyte growth factor,HGF_CANLF,Hepatocyte growth factor,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,KEGG:cfa:403441`KO:K05460,COG5640^protease,PF00024.26^PAN_1^PAN domain^59-117^E:1.8e-09,PF00051.18^Kringle^Kringle domain^124-197^E:1e-24,PF00051.18^Kringle^Kringle domain^202-279^E:3.4e-28,PF00051.18^Kringle^Kringle domain^296-374^E:1.5e-29,PF00051.18^Kringle^Kringle domain^382-462^E:5.6e-24,,
yes,AD,HGF,DN12277_c0_g1_i11,DN12277_c0_g1,HGF_HUMAN,Hepatocyte growth factor,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0042056^molecular_function^chemoattractant activity,.,NA,NA,NA,NA,KEGG:hsa:3082`KO:K05460,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN49745_c0_g2_i1,DN49745_c0_g2,HGF_FELCA,Hepatocyte growth factor,.,NA,GO:0042056^molecular_function^chemoattractant activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0000187^biological_process^activation of MAPK activity,.,NA,NA,NA,NA,KEGG:fca:493705`KO:K05460,COG5640^protease,.,NA,NA,NA,NA,,
yes,AD,HGF,DN82470_c0_g1_i1,DN82470_c0_g1,HGFA_CANLF,Hepatocyte growth factor activator,HGFA_MOUSE,Hepatocyte growth factor activator,GO:0005615^cellular_component^extracellular space,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0005509^molecular_function^calcium ion binding,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0006508^biological_process^proteolysis,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0006508^biological_process^proteolysis,KEGG:mmu:54426`KO:K09631,COG5640^protease,PF00089.26^Trypsin^Trypsin^2-140^E:1.5e-37,PF09342.11^DUF1986^Domain of unknown function (DUF1986)^14-123^E:5.7e-07,NA,NA,NA,,
yes,AD,HGF,DN133058_c0_g1_i1,DN133058_c0_g1,HGFA_MOUSE,Hepatocyte growth factor activator,HGFA_MOUSE,Hepatocyte growth factor activator,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0006508^biological_process^proteolysis,GO:0005737^cellular_component^cytoplasm,GO:0005615^cellular_component^extracellular space,GO:0005791^cellular_component^rough endoplasmic reticulum,GO:0004252^molecular_function^serine-type endopeptidase activity,GO:0006508^biological_process^proteolysis,KEGG:mmu:54426`KO:K09631,COG5640^protease,PF00040.19^fn2^Fibronectin type II domain^1-19^E:1.3e-06,PF00008.27^EGF^EGF-like domain^30-61^E:2.8e-05,PF12661.7^hEGF^Human growth factor-like EGF^35-55^E:0.088,PF00039.18^fn1^Fibronectin type I domain^68-103^E:7.6e-11,PF00051.18^Kringle^Kringle domain^152-233^E:4.7e-25,,
yes,AD,HSP70,DN71_c0_g1_i10,DN71_c0_g1,HSP70_CHICK,Heat shock 70 kDa protein,HSP70_CHICK,Heat shock 70 kDa protein,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0043204^cellular_component^perikaryon,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0043204^cellular_component^perikaryon,KEGG:gga:423504`KO:K03283,COG0443^Heat shock protein,PF00012.20^HSP70^Hsp70 protein^7-615^E:1.3e-263,PF06723.13^MreB_Mbl^MreB/Mbl protein^127-377^E:9.3e-16,NA,NA,NA,,
yes,AD,HSP70,DN71_c0_g1_i8,DN71_c0_g1,HSP70_CHICK,Heat shock 70 kDa protein,HSP70_CHICK,Heat shock 70 kDa protein,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0043204^cellular_component^perikaryon,GO:0005623^cellular_component^cell,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0043204^cellular_component^perikaryon,KEGG:gga:423504`KO:K03283,COG0443^Heat shock protein,PF00012.20^HSP70^Hsp70 protein^1-164^E:1.1e-45,NA,NA,NA,NA,,
yes,AD,HSP70,DN43383_c0_g1_i1,DN43383_c0_g1,F10A1_CHICK,Hsc70-interacting protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,.,NA,NA,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),.,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i4,DN1159_c0_g1,PFD5_HUMAN,Prefoldin subunit 5,PFD5_PONAB,Prefoldin subunit 5,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,NA,KEGG:pon:100172545`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i6,DN1159_c0_g1,PFD5_PONAB,Prefoldin subunit 5,.,NA,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,NA,.,NA,NA,NA,NA,KEGG:pon:100172545`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i9,DN1159_c0_g1,PFD5_HUMAN,Prefoldin subunit 5,PFD5_PONAB,Prefoldin subunit 5,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,NA,KEGG:pon:100172545`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF02996.17^Prefoldin^Prefoldin subunit^78-178^E:1.4e-25,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i1,DN1159_c0_g1,PFD5_HUMAN,Prefoldin subunit 5,PFD5_HUMAN,Prefoldin subunit 5,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,KEGG:hsa:5204`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF02996.17^Prefoldin^Prefoldin subunit^28-100^E:1.7e-16,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i3,DN1159_c0_g1,PFD5_PONAB,Prefoldin subunit 5,.,NA,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,NA,.,NA,NA,NA,NA,KEGG:pon:100172545`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i5,DN1159_c0_g1,PFD5_HUMAN,Prefoldin subunit 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,.,NA,NA,NA,NA,KEGG:hsa:5204`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i7,DN1159_c0_g1,PFD5_HUMAN,Prefoldin subunit 5,PFD5_MOUSE,Prefoldin subunit 5,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0003714^molecular_function^transcription corepressor activity,GO:0051082^molecular_function^unfolded protein binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,KEGG:mmu:56612`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF02996.17^Prefoldin^Prefoldin subunit^28-146^E:2.3e-27,PF12998.7^ING^Inhibitor of growth proteins N-terminal histone-binding^110-149^E:0.054,NA,NA,NA,,
no,AD,HSP70,DN1159_c0_g1_i10,DN1159_c0_g1,PFD5_PONAB,Prefoldin subunit 5,PFD5_MOUSE,Prefoldin subunit 5,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051082^molecular_function^unfolded protein binding,GO:0090090^biological_process^negative regulation of canonical Wnt signaling pathway,KEGG:mmu:56612`KO:K04797,"COG1730^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF02996.17^Prefoldin^Prefoldin subunit^78-194^E:9.6e-27,NA,NA,NA,NA,,
yes,AD,HSP70,DN75143_c0_g1_i1,DN75143_c0_g1,F10A1_RAT,Hsc70-interacting protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0051087^molecular_function^chaperone binding,GO:0032564^molecular_function^dATP binding,GO:0030544^molecular_function^Hsp70 protein binding,.,NA,NA,NA,NA,KEGG:rno:81800`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),.,NA,NA,NA,NA,,
yes,AD,HSP70,DN5464_c0_g1_i1,DN5464_c0_g1,HPBP1_MOUSE,Hsp70-binding protein 1,HPBP1_MOUSE,Hsp70-binding protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005783^cellular_component^endoplasmic reticulum,GO:0000774^molecular_function^adenyl-nucleotide exchange factor activity,GO:0031625^molecular_function^ubiquitin protein ligase binding,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0005737^cellular_component^cytoplasm,GO:0005783^cellular_component^endoplasmic reticulum,GO:0000774^molecular_function^adenyl-nucleotide exchange factor activity,GO:0031625^molecular_function^ubiquitin protein ligase binding,GO:0032436^biological_process^positive regulation of proteasomal ubiquitin-dependent protein catabolic process,KEGG:mmu:66245`KO:K09562,"ENOG410Y90B^HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1",PF00514.23^Arm^Armadillo/beta-catenin-like repeat^250-288^E:0.00015,NA,NA,NA,NA,,
yes,AD,HSP70,DN7755_c0_g1_i7,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,F10A1_CHICK,Hsc70-interacting protein,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),PF13181.6^TPR_8^Tetratricopeptide repeat^52-82^E:0.021,PF13432.6^TPR_16^Tetratricopeptide repeat^55-110^E:0.00019,PF17830.1^STI1^STI1 domain^210-257^E:2.2e-12,NA,NA,,
yes,AD,HSP70,DN7755_c0_g1_i8,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,F10A1_CHICK,Hsc70-interacting protein,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),PF18253.1^HipN^Hsp70-interacting protein N N-terminal domain^2-43^E:7.2e-20,PF13181.6^TPR_8^Tetratricopeptide repeat^148-178^E:0.032,PF13432.6^TPR_16^Tetratricopeptide repeat^151-206^E:0.00031,PF17830.1^STI1^STI1 domain^306-353^E:3.5e-12,NA,,
yes,AD,HSP70,DN7755_c0_g1_i5,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,.,NA,NA,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),.,NA,NA,NA,NA,,
yes,AD,HSP70,DN7755_c0_g1_i6,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,F10A1_CHICK,Hsc70-interacting protein,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),PF13181.6^TPR_8^Tetratricopeptide repeat^132-162^E:0.03,PF13432.6^TPR_16^Tetratricopeptide repeat^135-190^E:0.00029,PF17830.1^STI1^STI1 domain^290-337^E:3.3e-12,NA,NA,,
yes,AD,HSP70,DN7755_c0_g1_i3,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,F10A1_CHICK,Hsc70-interacting protein,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),PF13181.6^TPR_8^Tetratricopeptide repeat^132-162^E:0.03,PF13432.6^TPR_16^Tetratricopeptide repeat^135-190^E:0.00029,PF17830.1^STI1^STI1 domain^290-337^E:3.3e-12,NA,NA,,
yes,AD,HSP70,DN7755_c0_g1_i4,DN7755_c0_g1,F10A1_CHICK,Hsc70-interacting protein,F10A1_CHICK,Hsc70-interacting protein,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0046983^molecular_function^protein dimerization activity,GO:0051085^biological_process^chaperone cofactor-dependent protein refolding,NA,NA,KEGG:gga:418003`KO:K09560,ENOG410XR19^suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),PF13181.6^TPR_8^Tetratricopeptide repeat^132-162^E:0.026,PF13432.6^TPR_16^Tetratricopeptide repeat^135-190^E:0.00024,NA,NA,NA,,
no,AD,HSP70,DN1764_c1_g1_i4,DN1764_c1_g1,PFD4_HUMAN,Prefoldin subunit 4,PFD4_HUMAN,Prefoldin subunit 4,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,KEGG:hsa:5203`KO:K09550,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF01920.20^Prefoldin_2^Prefoldin subunit^20-126^E:3.2e-25,NA,NA,NA,NA,,
no,AD,HSP70,DN1764_c1_g1_i5,DN1764_c1_g1,PFD4_BOVIN,Prefoldin subunit 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,.,NA,NA,NA,NA,KEGG:bta:514621`KO:K09550,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN1764_c1_g2_i1,DN1764_c1_g2,PFD4_HUMAN,Prefoldin subunit 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,.,NA,NA,NA,NA,KEGG:hsa:5203`KO:K09550,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
no,AD,HSP70,DN24060_c1_g1_i3,DN24060_c1_g1,PFD6_BOVIN,Prefoldin subunit 6,PFD6_BOVIN,Prefoldin subunit 6,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016272^cellular_component^prefoldin complex,GO:0051087^molecular_function^chaperone binding,GO:0051082^molecular_function^unfolded protein binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016272^cellular_component^prefoldin complex,GO:0051087^molecular_function^chaperone binding,GO:0051082^molecular_function^unfolded protein binding,KEGG:bta:509914`KO:K04798,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF01920.20^Prefoldin_2^Prefoldin subunit^49-143^E:1.7e-22,NA,NA,NA,NA,,
no,AD,HSP70,DN24060_c1_g1_i4,DN24060_c1_g1,PFD6_MOUSE,Prefoldin subunit 6,PFD6_BOVIN,Prefoldin subunit 6,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,GO:0051087^molecular_function^chaperone binding,GO:0051082^molecular_function^unfolded protein binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016272^cellular_component^prefoldin complex,GO:0051087^molecular_function^chaperone binding,GO:0051082^molecular_function^unfolded protein binding,KEGG:bta:509914`KO:K04798,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",PF01920.20^Prefoldin_2^Prefoldin subunit^30-134^E:3.5e-25,NA,NA,NA,NA,,
no,AD,HSP70,DN302112_c0_g1_i1,DN302112_c0_g1,PFD4_BOVIN,Prefoldin subunit 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0016272^cellular_component^prefoldin complex,.,NA,NA,NA,NA,KEGG:bta:514621`KO:K09550,"COG1382^Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity)",.,NA,NA,NA,NA,,
yes,AD,HSP90,DN22936_c0_g2_i2,DN22936_c0_g2,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,KEGG:bta:510572,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN221_c4_g1_i1,DN221_c4_g1,CD37L_PONAB,Hsp90 co-chaperone Cdc37-like 1,.,NA,GO:0005737^cellular_component^cytoplasm,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172709,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN4003_c2_g1_i1,DN4003_c2_g1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,KEGG:bta:510572,ENOG410XTCZ^cell division cycle 37 homolog (S,PF08565.11^CDC37_M^Cdc37 Hsp90 binding domain^66-167^E:9.6e-20,NA,NA,NA,NA,,
yes,AD,HSP90,DN4003_c2_g1_i2,DN4003_c2_g1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,KEGG:bta:510572,ENOG410XTCZ^cell division cycle 37 homolog (S,PF08565.11^CDC37_M^Cdc37 Hsp90 binding domain^162-263^E:2e-19,NA,NA,NA,NA,,
yes,AD,HSP90,DN10010_c2_g1_i1,DN10010_c2_g1,CDC37_CHICK,Hsp90 co-chaperone Cdc37,CDC37_CHICK,Hsp90 co-chaperone Cdc37,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0019901^molecular_function^protein kinase binding,GO:0051082^molecular_function^unfolded protein binding,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0019901^molecular_function^protein kinase binding,GO:0051082^molecular_function^unfolded protein binding,KEGG:gga:395430`KO:K09554,.,PF03234.14^CDC37_N^Cdc37 N terminal kinase binding^36-146^E:5.1e-15,PF08565.11^CDC37_M^Cdc37 Hsp90 binding domain^198-307^E:1.2e-26,PF08564.10^CDC37_C^Cdc37 C terminal domain^327-407^E:7e-17,NA,NA,,
yes,AD,HSP90,DN36971_c0_g1_i1,DN36971_c0_g1,CDC37_CHICK,Hsp90 co-chaperone Cdc37,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0019901^molecular_function^protein kinase binding,GO:0051082^molecular_function^unfolded protein binding,.,NA,NA,NA,NA,KEGG:gga:395430`KO:K09554,.,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN17919_c0_g1_i1,DN17919_c0_g1,CDC37_RAT,Hsp90 co-chaperone Cdc37,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0032587^cellular_component^ruffle membrane,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,.,NA,NA,NA,NA,KEGG:rno:114562`KO:K09554,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN17919_c0_g2_i2,DN17919_c0_g2,CDC37_MOUSE,Hsp90 co-chaperone Cdc37,.,NA,GO:0101031^cellular_component^chaperone complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:1990565^cellular_component^HSP90-CDC37 chaperone complex,GO:0032991^cellular_component^protein-containing complex,.,NA,NA,NA,NA,KEGG:mmu:12539`KO:K09554,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN1856_c2_g1_i3,DN1856_c2_g1,CD37L_BOVIN,Hsp90 co-chaperone Cdc37-like 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0051087^molecular_function^chaperone binding,GO:0031072^molecular_function^heat shock protein binding,GO:0051082^molecular_function^unfolded protein binding,GO:0006457^biological_process^protein folding,.,NA,NA,NA,NA,KEGG:bta:510572,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,AD,HSP90,DN28085_c0_g1_i1,DN28085_c0_g1,CDC37_MOUSE,Hsp90 co-chaperone Cdc37,.,NA,GO:0101031^cellular_component^chaperone complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:1990565^cellular_component^HSP90-CDC37 chaperone complex,GO:0032991^cellular_component^protein-containing complex,.,NA,NA,NA,NA,KEGG:mmu:12539`KO:K09554,ENOG410XTCZ^cell division cycle 37 homolog (S,.,NA,NA,NA,NA,,
yes,JO,IFI6,DN2932_c0_g1_i6,DN2932_c0_g1,IFI6_BOVIN,Interferon alpha-inducible protein 6 {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0006915^biological_process^apoptotic process,GO:0098586^biological_process^cellular response to virus,.,NA,NA,NA,NA,KEGG:bta:512913,"ENOG41115QI^Interferon, alpha-inducible protein 6",.,NA,NA,NA,NA,,
yes,JO,IFIH1,DN24849_c0_g1_i14,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:2.1e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:2.3e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:3.6e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:5.1e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:8.7e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i1,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:2.2e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:2.4e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:3.8e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:5.5e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:9.2e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i10,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:1.2e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:1.8e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:2.2e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:3.7e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i7,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,.,NA,NA,NA,NA,KEGG:hsa:64135`KO:K12647,COG1111^helicase,.,NA,NA,NA,NA,,
yes,JO,IFIH1,DN24849_c0_g1_i8,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_MOUSE,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:mmu:71586`KO:K12647,COG1111^helicase,PF11648.8^RIG-I_C-RD^C-terminal domain of RIG-I^10-94^E:2.1e-24,NA,NA,NA,NA,,
yes,JO,IFIH1,DN24849_c0_g1_i13,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1.2e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:1.4e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:2.2e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:2.7e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:4.6e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i11,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:1.2e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:1.8e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:2.2e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:3.7e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i6,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1.5e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:1.6e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:2.6e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:3.4e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:5.7e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i5,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1.5e-20,NA,NA,NA,NA,,
yes,JO,IFIH1,DN24849_c0_g1_i3,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,PF16739.5^CARD_2^Caspase recruitment domain^11-97^E:1.9e-19,PF16739.5^CARD_2^Caspase recruitment domain^108-198^E:2.1e-21,PF00619.21^CARD^Caspase recruitment domain^114-197^E:3.4e-08,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^303-486^E:4.7e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^305-484^E:7.9e-17,,
yes,JO,IFIH1,DN24849_c0_g1_i4,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:hsa:64135`KO:K12647,COG1111^helicase,"PF04851.15^ResIII^Type III restriction enzyme, res subunit^31-214^E:3.2e-19",PF00270.29^DEAD^DEAD/DEAH box helicase^33-212^E:5.5e-17,PF18766.1^SWI2_SNF2^SWI2/SNF2 ATPase^53-185^E:4.1e-06,PF18119.1^RIG-I_C^RIG-I receptor C-terminal domain^246-396^E:4.8e-38,PF00271.31^Helicase_C^Helicase conserved C-terminal domain^413-529^E:8.7e-19,,
yes,JO,IFIH1,DN24849_c0_g1_i16,DN24849_c0_g1,IFIH1_HUMAN,Interferon-induced helicase C domain-containing protein 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,.,NA,NA,NA,NA,KEGG:hsa:64135`KO:K12647,COG1111^helicase,.,NA,NA,NA,NA,,
yes,JO,IFIH1,DN406680_c0_g1_i1,DN406680_c0_g1,IFIH1_MOUSE,Interferon-induced helicase C domain-containing protein 1,IFIH1_MOUSE,Interferon-induced helicase C domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0003677^molecular_function^DNA binding,GO:0003725^molecular_function^double-stranded RNA binding,KEGG:mmu:71586`KO:K12647,COG1111^helicase,.,NA,NA,NA,NA,,
yes,JO,IFIT5,DN6178_c0_g1_i1,DN6178_c0_g1,IFIT5_HUMAN,Interferon-induced protein with tetratricopeptide repeats 5,IFIT5_HUMAN,Interferon-induced protein with tetratricopeptide repeats 5,GO:0015629^cellular_component^actin cytoskeleton,GO:0045177^cellular_component^apical part of cell,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,GO:0015629^cellular_component^actin cytoskeleton,GO:0045177^cellular_component^apical part of cell,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:24138,COG0457^repeat-containing protein,PF13181.6^TPR_8^Tetratricopeptide repeat^96-118^E:0.13,PF13181.6^TPR_8^Tetratricopeptide repeat^147-171^E:0.13,PF02071.20^NSF^Aromatic-di-Alanine (AdAR) repeat^153-162^E:410,PF08238.12^Sel1^Sel1 repeat^157-167^E:1400,PF13181.6^TPR_8^Tetratricopeptide repeat^258-281^E:0.094,,
yes,JO,IFN,DN39690_c0_g1_i3,DN39690_c0_g1,IFNG_ANAPL,Interferon gamma,IFNG_ANAPL,Interferon gamma,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,KEGG:apla:101790439`KO:K04687,.,PF00714.17^IFN-gamma^Interferon gamma^12-123^E:6.7e-22,NA,NA,NA,NA,,
yes,JO,IFN,DN39690_c0_g1_i2,DN39690_c0_g1,IFNG_ANAPL,Interferon gamma,IFNG_ANAPL,Interferon gamma,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,KEGG:apla:101790439`KO:K04687,.,PF00714.17^IFN-gamma^Interferon gamma^5-120^E:1.7e-22,NA,NA,NA,NA,,
yes,JO,IFN,DN39690_c0_g1_i5,DN39690_c0_g1,IFNG_ANAPL,Interferon gamma,IFNG_ANAPL,Interferon gamma,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005133^molecular_function^interferon-gamma receptor binding,GO:0048143^biological_process^astrocyte activation,GO:0007050^biological_process^cell cycle arrest,KEGG:apla:101790439`KO:K04687,.,PF00714.17^IFN-gamma^Interferon gamma^27-153^E:1.7e-26,NA,NA,NA,NA,,
yes,JO,IFN,DN30848_c1_g1_i2,DN30848_c1_g1,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,PF00143.19^Interferon^Interferon alpha/beta domain^34-190^E:2.5e-39,NA,NA,NA,NA,,
yes,JO,IFN,DN30848_c1_g1_i3,DN30848_c1_g1,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,PF00143.19^Interferon^Interferon alpha/beta domain^34-189^E:1.4e-38,NA,NA,NA,NA,,
yes,JO,IFN,DN30848_c1_g1_i4,DN30848_c1_g1,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,PF00143.19^Interferon^Interferon alpha/beta domain^34-190^E:1.7e-38,NA,NA,NA,NA,,
yes,JO,IFN,DN30848_c1_g2_i3,DN30848_c1_g2,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,PF00143.19^Interferon^Interferon alpha/beta domain^34-189^E:1.1e-38,NA,NA,NA,NA,,
yes,JO,IFN,DN30848_c1_g2_i2,DN30848_c1_g2,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,PF00143.19^Interferon^Interferon alpha/beta domain^34-189^E:1.1e-38,NA,NA,NA,NA,,
yes,JO,IFN,DN30475_c0_g1_i1,DN30475_c0_g1,IFNL3_CHICK,Interferon lambda-3,IFNL3_CHICK,Interferon lambda-3,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0051607^biological_process^defense response to virus,GO:0045087^biological_process^innate immune response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0051607^biological_process^defense response to virus,GO:0045087^biological_process^innate immune response,KEGG:gga:101751261`KEGG:gga:770778`KO:K22669,"ENOG410ZDRD^interferon, lambda",PF15177.6^IL28A^Interleukin-28A^73-224^E:3.1e-50,NA,NA,NA,NA,,
yes,JO,IFN,DN30475_c0_g1_i2,DN30475_c0_g1,IFNL3_CHICK,Interferon lambda-3,IFNL3_CHICK,Interferon lambda-3,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0051607^biological_process^defense response to virus,GO:0045087^biological_process^innate immune response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0051607^biological_process^defense response to virus,GO:0045087^biological_process^innate immune response,KEGG:gga:101751261`KEGG:gga:770778`KO:K22669,"ENOG410ZDRD^interferon, lambda",PF15177.6^IL28A^Interleukin-28A^73-126^E:6.5e-11,NA,NA,NA,NA,,
yes,JO,IFN,DN195013_c0_g1_i2,DN195013_c0_g1,IFN_ANAPL,Interferon,IFN_ANAPL,Interferon,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,IFN,DN178217_c0_g1_i1,DN178217_c0_g1,IFNA2_HORSE,Interferon alpha-2,IFNA2_HORSE,Interferon alpha-2,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0002250^biological_process^adaptive immune response,GO:0030183^biological_process^B cell differentiation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0002250^biological_process^adaptive immune response,GO:0030183^biological_process^B cell differentiation,.,"ENOG410ZH91^Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes a protein kinase and an oligoadenylate synthetase",PF00143.19^Interferon^Interferon alpha/beta domain^27-181^E:3e-48,NA,NA,NA,NA,,
yes,JO,IFN,DN385347_c0_g1_i1,DN385347_c0_g1,IFN_ANAPL,Interferon,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005132^molecular_function^type I interferon receptor binding,GO:0051607^biological_process^defense response to virus,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,MJ,IGF,DN3160_c0_g1_i6,DN3160_c0_g1,PIGF_MOUSE,Phosphatidylinositol-glycan biosynthesis class F protein,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016780^molecular_function^phosphotransferase activity, for other substituted phosphate groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:mmu:18701`KO:K05287,"ENOG4111B1J^phosphatidylinositol glycan anchor biosynthesis, class F",.,NA,NA,NA,NA,,
no,MJ,IGF,DN3160_c0_g1_i2,DN3160_c0_g1,PIGF_MOUSE,Phosphatidylinositol-glycan biosynthesis class F protein,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016780^molecular_function^phosphotransferase activity, for other substituted phosphate groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:mmu:18701`KO:K05287,"ENOG4111B1J^phosphatidylinositol glycan anchor biosynthesis, class F",.,NA,NA,NA,NA,,
no,MJ,IGF,DN3160_c0_g1_i1,DN3160_c0_g1,PIGF_MOUSE,Phosphatidylinositol-glycan biosynthesis class F protein,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016780^molecular_function^phosphotransferase activity, for other substituted phosphate groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:mmu:18701`KO:K05287,"ENOG4111B1J^phosphatidylinositol glycan anchor biosynthesis, class F",.,NA,NA,NA,NA,,
no,MJ,IGF,DN89142_c0_g1_i1,DN89142_c0_g1,IGFN1_HUMAN,Immunoglobulin-like and fibronectin type III domain-containing protein 1,IGFN1_HUMAN,Immunoglobulin-like and fibronectin type III domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,KEGG:hsa:91156,ENOG410XQFD^myosin light chain kinase,PF00041.21^fn3^Fibronectin type III domain^59-141^E:1.9e-14,PF07679.16^I-set^Immunoglobulin I-set domain^171-248^E:3.3e-12,PF13927.6^Ig_3^Immunoglobulin domain^173-235^E:3.2e-07,PF11465.8^Receptor_2B4^Natural killer cell receptor 2B4^211-250^E:3.5e-05,PF00041.21^fn3^Fibronectin type III domain^261-338^E:1.5e-06,,
no,MJ,IGF,DN95796_c0_g2_i1,DN95796_c0_g2,IGF1_CHICK,Insulin-like growth factor I,IGF1_CHICK,Insulin-like growth factor I,GO:0035867^cellular_component^alphav-beta3 integrin-IGF-1-IGF1R complex,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0042567^cellular_component^insulin-like growth factor ternary complex,GO:0008083^molecular_function^growth factor activity,GO:0035867^cellular_component^alphav-beta3 integrin-IGF-1-IGF1R complex,GO:0005623^cellular_component^cell,GO:0005615^cellular_component^extracellular space,GO:0042567^cellular_component^insulin-like growth factor ternary complex,GO:0008083^molecular_function^growth factor activity,KEGG:gga:418090`KO:K05459,ENOG4111MIV^Insulin-like growth factor 1 (Somatomedin C),PF00049.18^Insulin^Insulin/IGF/Relaxin family^52-109^E:5.5e-12,NA,NA,NA,NA,,
no,MJ,IGF,DN19970_c0_g2_i2,DN19970_c0_g2,IGF1R_HUMAN,Insulin-like growth factor 1 receptor,IGF1R_HUMAN,Insulin-like growth factor 1 receptor,GO:0035867^cellular_component^alphav-beta3 integrin-IGF-1-IGF1R complex,GO:0030424^cellular_component^axon,GO:0005899^cellular_component^insulin receptor complex,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0035867^cellular_component^alphav-beta3 integrin-IGF-1-IGF1R complex,GO:0030424^cellular_component^axon,GO:0005899^cellular_component^insulin receptor complex,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:hsa:3480`KO:K05087,COG0515^Serine Threonine protein kinase,PF01030.24^Recep_L_domain^Receptor L domain^51-160^E:1.4e-27,PF00757.20^Furin-like^Furin-like cysteine rich region^176-333^E:7.6e-40,PF01030.24^Recep_L_domain^Receptor L domain^351-459^E:1.2e-29,PF00041.21^fn3^Fibronectin type III domain^835-916^E:1.2e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^1001-1197^E:2.1e-65,,
no,MJ,IGF,DN19970_c0_g2_i1,DN19970_c0_g2,IGF1R_HUMAN,Insulin-like growth factor 1 receptor,IGF1R_RAT,Insulin-like growth factor 1 receptor,GO:0035867^cellular_component^alphav-beta3 integrin-IGF-1-IGF1R complex,GO:0030424^cellular_component^axon,GO:0005899^cellular_component^insulin receptor complex,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0030424^cellular_component^axon,GO:0005901^cellular_component^caveola,GO:0005737^cellular_component^cytoplasm,GO:0005899^cellular_component^insulin receptor complex,GO:0005887^cellular_component^integral component of plasma membrane,KEGG:rno:25718`KO:K05087,COG0515^Serine Threonine protein kinase,PF01030.24^Recep_L_domain^Receptor L domain^51-160^E:1.7e-27,PF00757.20^Furin-like^Furin-like cysteine rich region^176-333^E:9.1e-40,PF01030.24^Recep_L_domain^Receptor L domain^351-459^E:1.4e-29,PF00041.21^fn3^Fibronectin type III domain^835-916^E:1.4e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^1001-1264^E:5.9e-95,,
no,MJ,IGF,DN16086_c2_g1_i1,DN16086_c2_g1,IGF2_CHICK,Insulin-like growth factor II,IGF2_CHICK,Insulin-like growth factor II,GO:0005615^cellular_component^extracellular space,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,GO:0005158^molecular_function^insulin receptor binding,GO:0005159^molecular_function^insulin-like growth factor receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,GO:0005158^molecular_function^insulin receptor binding,GO:0005159^molecular_function^insulin-like growth factor receptor binding,KEGG:gga:395097`KO:K13769,ENOG4111KP2^insulin-like growth factor 2 (somatomedin A),PF00049.18^Insulin^Insulin/IGF/Relaxin family^67-94^E:2.4e-05,PF00049.18^Insulin^Insulin/IGF/Relaxin family^96-121^E:3.7e-06,PF08365.11^IGF2_C^Insulin-like growth factor II E-peptide^154-210^E:9.8e-29,NA,NA,,
no,MJ,IGF,DN114088_c0_g1_i1,DN114088_c0_g1,IGFN1_MOUSE,Immunoglobulin-like and fibronectin type III domain-containing protein 1,IGFN1_MOUSE,Immunoglobulin-like and fibronectin type III domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,KEGG:mmu:226438,ENOG410YB5P^immunoglobulin-like and fibronectin type III domain containing 1,.,NA,NA,NA,NA,,
no,MJ,IGF,DN163154_c0_g1_i1,DN163154_c0_g1,IGF1R_RAT,Insulin-like growth factor 1 receptor,.,NA,GO:0030424^cellular_component^axon,GO:0005901^cellular_component^caveola,GO:0005737^cellular_component^cytoplasm,GO:0005899^cellular_component^insulin receptor complex,GO:0005887^cellular_component^integral component of plasma membrane,.,NA,NA,NA,NA,KEGG:rno:25718`KO:K05087,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,MJ,IGF,DN116207_c0_g1_i1,DN116207_c0_g1,IGFN1_HUMAN,Immunoglobulin-like and fibronectin type III domain-containing protein 1,IGFN1_HUMAN,Immunoglobulin-like and fibronectin type III domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,KEGG:hsa:91156,ENOG410XQFD^myosin light chain kinase,PF07679.16^I-set^Immunoglobulin I-set domain^42-114^E:5.8e-08,NA,NA,NA,NA,,
no,MJ,IGF,DN235681_c0_g1_i1,DN235681_c0_g1,IGFN1_MOUSE,Immunoglobulin-like and fibronectin type III domain-containing protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:226438,ENOG410YB5P^immunoglobulin-like and fibronectin type III domain containing 1,.,NA,NA,NA,NA,,
no,MJ,IGF,DN302927_c0_g1_i1,DN302927_c0_g1,IGFN1_MOUSE,Immunoglobulin-like and fibronectin type III domain-containing protein 1,IGFN1_MOUSE,Immunoglobulin-like and fibronectin type III domain-containing protein 1,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,GO:0005634^cellular_component^nucleus,GO:0030017^cellular_component^sarcomere,GO:0030018^cellular_component^Z disc,NA,NA,KEGG:mmu:226438,ENOG410YB5P^immunoglobulin-like and fibronectin type III domain containing 1,PF00047.25^ig^Immunoglobulin domain^2-78^E:0.00016,PF07679.16^I-set^Immunoglobulin I-set domain^3-85^E:1.1e-15,PF13927.6^Ig_3^Immunoglobulin domain^5-72^E:6.1e-09,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i13,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^43-172^E:7.5e-09,PF00168.30^C2^C2 domain^48-156^E:1.4e-09,PF18111.1^RPGR1_C^Retinitis pigmentosa G-protein regulator interacting C-terminal^364-526^E:1.5e-56,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i8,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^339-479^E:1e-59,PF00168.30^C2^C2 domain^527-629^E:1.5e-08,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i10,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,.,NA,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i11,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^596-736^E:2.7e-59,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^779-908^E:3.1e-08,PF00168.30^C2^C2 domain^784-892^E:5.1e-09,PF18111.1^RPGR1_C^Retinitis pigmentosa G-protein regulator interacting C-terminal^1100-1262^E:6.5e-56,NA,,
no,MJ,IgM,DN2003_c1_g1_i1,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^339-479^E:7.1e-60,NA,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i2,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^331-471^E:2e-59,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^514-643^E:2.3e-08,PF00168.30^C2^C2 domain^519-627^E:3.7e-09,PF18111.1^RPGR1_C^Retinitis pigmentosa G-protein regulator interacting C-terminal^835-997^E:4.6e-56,NA,,
no,MJ,IgM,DN2003_c1_g1_i4,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,PF11618.8^C2-C2_1^First C2 domain of RPGR-interacting protein 1^25-129^E:7.2e-08,PF00168.30^C2^C2 domain^30-132^E:6.6e-10,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i7,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,.,NA,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g1_i9,DN2003_c1_g1,FTM_HUMAN,Protein fantom,FTM_HUMAN,Protein fantom,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,.,NA,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g2_i1,DN2003_c1_g2,FTM_HUMAN,Protein fantom,.,NA,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,.,NA,NA,NA,NA,KEGG:hsa:23322`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,.,NA,NA,NA,NA,,
no,MJ,IgM,DN2003_c1_g3_i1,DN2003_c1_g3,FTM_MOUSE,Protein fantom,.,NA,GO:0005879^cellular_component^axonemal microtubule,GO:0005930^cellular_component^axoneme,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005813^cellular_component^centrosome,.,NA,NA,NA,NA,KEGG:mmu:244585`KO:K16550,ENOG410YNUX^retinitis pigmentosa GTPase regulator interacting protein 1,.,NA,NA,NA,NA,,
no,MJ,IgM,DN5124_c0_g3_i1,DN5124_c0_g3,MPIP1_MOUSE,M-phase inducer phosphatase 1,AP5S1_HUMAN,AP-5 complex subunit sigma-1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0051087^molecular_function^chaperone binding,GO:0004721^molecular_function^phosphoprotein phosphatase activity,GO:0019901^molecular_function^protein kinase binding,GO:0030119^cellular_component^AP-type membrane coat adaptor complex,GO:0005829^cellular_component^cytosol,GO:0005770^cellular_component^late endosome,GO:0031902^cellular_component^late endosome membrane,GO:0005765^cellular_component^lysosomal membrane,KEGG:hsa:55317`KO:K19024,"ENOG4111NAX^adaptor-related protein complex 5, sigma 1 subunit",PF15001.6^AP-5_subunit_s1^AP-5 complex subunit sigma-1^1-192^E:4.5e-31,NA,NA,NA,NA,,
no,MJ,IgM,DN8249_c1_g2_i1,DN8249_c1_g2,.,NA,RSGI2_CLOTH,Anti-sigma-I factor RsgI2 {ECO:0000305},.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030248^molecular_function^cellulose binding,GO:0046872^molecular_function^metal ion binding,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:cth:Cthe_0267,ENOG41123G8^NA,.,NA,NA,NA,NA,,
no,MJ,IgM,DN66763_c0_g1_i7,DN66763_c0_g1,.,NA,RSGI2_CLOTH,Anti-sigma-I factor RsgI2 {ECO:0000305},.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030248^molecular_function^cellulose binding,GO:0046872^molecular_function^metal ion binding,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:cth:Cthe_0267,ENOG41123G8^NA,.,NA,NA,NA,NA,,
no,MJ,IgM,DN92037_c0_g1_i1,DN92037_c0_g1,SGMR1_CHICK,Sigma non-opioid intracellular receptor 1,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:gga:100859748`KO:K20719,.,.,NA,NA,NA,NA,,
no,MJ,IgM,DN202_c0_g3_i1,DN202_c0_g3,IGM_HUMAN,Immunoglobulin mu heavy chain {ECO:0000305},.,NA,GO:0005576^cellular_component^extracellular region,GO:0019814^cellular_component^immunoglobulin complex,GO:0005886^cellular_component^plasma membrane,GO:0002250^biological_process^adaptive immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i2,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i9,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i10,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i17,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i11,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g1_i3,DN248_c0_g1,AP3S2_PONAB,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0008089^biological_process^anterograde axonal transport,.,NA,NA,NA,NA,KEGG:pon:100171891`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g2_i2,DN248_c0_g2,AP3S1_MOUSE,AP-3 complex subunit sigma-1,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN248_c0_g2_i1,DN248_c0_g2,AP3S1_MOUSE,AP-3 complex subunit sigma-1,AP3S1_MOUSE,AP-3 complex subunit sigma-1,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^58-204^E:4.2e-53,NA,NA,NA,NA,,
no,MJ,IgM,DN6539_c0_g1_i3,DN6539_c0_g1,RPGR_HUMAN,X-linked retinitis pigmentosa GTPase regulator,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0001750^cellular_component^photoreceptor outer segment,GO:0036126^cellular_component^sperm flagellum,.,NA,NA,NA,NA,KEGG:hsa:6103`KO:K19607,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,MJ,IgM,DN6539_c0_g1_i4,DN6539_c0_g1,RPGR_CANLF,X-linked retinitis pigmentosa GTPase regulator,RPGR_CANLF,X-linked retinitis pigmentosa GTPase regulator,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0036126^cellular_component^sperm flagellum,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0036126^cellular_component^sperm flagellum,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,KEGG:cfa:403726`KO:K19607,COG5184^regulator of chromosome condensation,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^77-105^E:6.3e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^92-140^E:4.7e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^131-157^E:1.2e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^144-194^E:1.9e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^181-210^E:1.5e-08,,
no,MJ,IgM,DN6539_c0_g1_i5,DN6539_c0_g1,RPGR_CANLF,X-linked retinitis pigmentosa GTPase regulator,RPGR_CANLF,X-linked retinitis pigmentosa GTPase regulator,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0036126^cellular_component^sperm flagellum,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0036126^cellular_component^sperm flagellum,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,KEGG:cfa:403726`KO:K19607,COG5184^regulator of chromosome condensation,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^77-105^E:6.1e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^92-140^E:4.5e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^131-157^E:1.2e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^144-194^E:1.8e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^181-210^E:1.4e-08,,
no,MJ,IgM,DN6539_c0_g1_i1,DN6539_c0_g1,RPGR_HUMAN,X-linked retinitis pigmentosa GTPase regulator,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0001750^cellular_component^photoreceptor outer segment,GO:0036126^cellular_component^sperm flagellum,.,NA,NA,NA,NA,KEGG:hsa:6103`KO:K19607,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,MJ,IgM,DN6539_c0_g1_i7,DN6539_c0_g1,RPGR_HUMAN,X-linked retinitis pigmentosa GTPase regulator,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005794^cellular_component^Golgi apparatus,GO:0001750^cellular_component^photoreceptor outer segment,GO:0036126^cellular_component^sperm flagellum,.,NA,NA,NA,NA,KEGG:hsa:6103`KO:K19607,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,MJ,IgM,DN12995_c0_g1_i6,DN12995_c0_g1,PEDF_MOUSE,Pigment epithelium-derived factor,.,NA,GO:0030424^cellular_component^axon,GO:0043203^cellular_component^axon hillock,GO:0005604^cellular_component^basement membrane,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,.,NA,NA,NA,NA,KEGG:mmu:20317`KO:K19614,COG4826^serine-type endopeptidase inhibitor activity,.,NA,NA,NA,NA,,
no,MJ,IgM,DN8169_c0_g1_i14,DN8169_c0_g1,.,NA,RSGI2_CLOTH,Anti-sigma-I factor RsgI2 {ECO:0000305},.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0030248^molecular_function^cellulose binding,GO:0046872^molecular_function^metal ion binding,GO:0005975^biological_process^carbohydrate metabolic process,KEGG:cth:Cthe_0267,ENOG41123G8^NA,.,NA,NA,NA,NA,,
no,MJ,IgM,DN26284_c0_g1_i5,DN26284_c0_g1,AP3S2_BOVIN,AP-3 complex subunit sigma-2,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:bta:508867`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN17245_c0_g1_i2,DN17245_c0_g1,AP2S1_RAT,AP-2 complex subunit sigma,AP2S1_RAT,AP-2 complex subunit sigma,GO:0030122^cellular_component^AP-2 adaptor complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,GO:0035615^molecular_function^clathrin adaptor activity,GO:0072583^biological_process^clathrin-dependent endocytosis,GO:0030122^cellular_component^AP-2 adaptor complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,GO:0035615^molecular_function^clathrin adaptor activity,GO:0072583^biological_process^clathrin-dependent endocytosis,KEGG:rno:65046`KO:K11827,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^18-107^E:3.4e-38,NA,NA,NA,NA,,
no,MJ,IgM,DN17245_c0_g1_i1,DN17245_c0_g1,AP2S1_RAT,AP-2 complex subunit sigma,AP2S1_RAT,AP-2 complex subunit sigma,GO:0030122^cellular_component^AP-2 adaptor complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,GO:0035615^molecular_function^clathrin adaptor activity,GO:0072583^biological_process^clathrin-dependent endocytosis,GO:0030122^cellular_component^AP-2 adaptor complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005886^cellular_component^plasma membrane,GO:0035615^molecular_function^clathrin adaptor activity,GO:0072583^biological_process^clathrin-dependent endocytosis,KEGG:rno:65046`KO:K11827,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^18-158^E:2.9e-62,NA,NA,NA,NA,,
no,MJ,IgM,DN7047_c1_g1_i4,DN7047_c1_g1,NLK_CANLF,Serine/threonine-protein kinase NLK,SGMR2_XENTR,Sigma intracellular receptor 2 {ECO:0000250|UniProtKB:Q5BJF2},GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004707^molecular_function^MAP kinase activity,GO:0016021^cellular_component^integral component of membrane,GO:0005764^cellular_component^lysosome,GO:0031965^cellular_component^nuclear membrane,GO:0005886^cellular_component^plasma membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,KEGG:xtr:448515,ENOG4111RR6^Transmembrane protein 97,PF10914.8^DUF2781^Protein of unknown function (DUF2781)^11-158^E:1.4e-45,NA,NA,NA,NA,,
no,MJ,IgM,DN7047_c1_g1_i5,DN7047_c1_g1,NLK_CANLF,Serine/threonine-protein kinase NLK,SGMR2_XENTR,Sigma intracellular receptor 2 {ECO:0000250|UniProtKB:Q5BJF2},GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004707^molecular_function^MAP kinase activity,GO:0016021^cellular_component^integral component of membrane,GO:0005764^cellular_component^lysosome,GO:0031965^cellular_component^nuclear membrane,GO:0005886^cellular_component^plasma membrane,GO:0005791^cellular_component^rough endoplasmic reticulum,KEGG:xtr:448515,ENOG4111RR6^Transmembrane protein 97,PF10914.8^DUF2781^Protein of unknown function (DUF2781)^11-158^E:1.4e-45,NA,NA,NA,NA,,
no,MJ,IgM,DN16417_c0_g1_i1,DN16417_c0_g1,1433S_SHEEP,14-3-3 protein sigma,1433S_HUMAN,14-3-3 protein sigma,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005634^cellular_component^nucleus,GO:0019904^molecular_function^protein domain specific binding,GO:0061436^biological_process^establishment of skin barrier,GO:0005829^cellular_component^cytosol,GO:0070062^cellular_component^extracellular exosome,GO:0005615^cellular_component^extracellular space,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,KEGG:hsa:2810`KO:K06644,COG5040^Tyrosine 3-monooxygenase tryptophan 5-monooxygenase activation protein,PF00244.20^14-3-3^14-3-3 protein^9-229^E:2.3e-102,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g1_i2,DN38381_c0_g1,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^1-141^E:9.7e-44,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g1_i5,DN38381_c0_g1,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},.,NA,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,.,NA,NA,NA,NA,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g1_i1,DN38381_c0_g1,AP4S1_MOUSE,AP-4 complex subunit sigma-1 {ECO:0000305},.,NA,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005802^cellular_component^trans-Golgi network,GO:0006886^biological_process^intracellular protein transport,GO:0016192^biological_process^vesicle-mediated transport,.,NA,NA,NA,NA,KEGG:mmu:11782`KO:K12403,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g1_i3,DN38381_c0_g1,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,PF01217.20^Clat_adaptor_s^Clathrin adaptor complex small chain^1-141^E:9.7e-44,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g1_i4,DN38381_c0_g1,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},.,NA,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,.,NA,NA,NA,NA,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN38381_c0_g4_i1,DN38381_c0_g4,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},.,NA,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,.,NA,NA,NA,NA,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN22086_c0_g1_i2,DN22086_c0_g1,AP3S1_MOUSE,AP-3 complex subunit sigma-1,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN7341_c1_g1_i3,DN7341_c1_g1,OPSX_HUMAN,Visual pigment-like receptor peropsin,OPSX_HUMAN,Visual pigment-like receptor peropsin,GO:0005887^cellular_component^integral component of plasma membrane,GO:0001750^cellular_component^photoreceptor outer segment,GO:0008020^molecular_function^G protein-coupled photoreceptor activity,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0071482^biological_process^cellular response to light stimulus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0001750^cellular_component^photoreceptor outer segment,GO:0008020^molecular_function^G protein-coupled photoreceptor activity,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0071482^biological_process^cellular response to light stimulus,KEGG:hsa:10692`KO:K04253,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^37-308^E:4.4e-12,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^43-294^E:1.5e-44,NA,NA,NA,,
no,MJ,IgM,DN10599_c0_g1_i1,DN10599_c0_g1,PEDF_MOUSE,Pigment epithelium-derived factor,PEDF_MOUSE,Pigment epithelium-derived factor,GO:0030424^cellular_component^axon,GO:0043203^cellular_component^axon hillock,GO:0005604^cellular_component^basement membrane,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030424^cellular_component^axon,GO:0043203^cellular_component^axon hillock,GO:0005604^cellular_component^basement membrane,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,KEGG:mmu:20317`KO:K19614,COG4826^serine-type endopeptidase inhibitor activity,PF00079.20^Serpin^Serpin (serine protease inhibitor)^56-414^E:1.7e-88,NA,NA,NA,NA,,
no,MJ,IgM,DN10599_c0_g1_i2,DN10599_c0_g1,PEDF_MOUSE,Pigment epithelium-derived factor,PEDF_MOUSE,Pigment epithelium-derived factor,GO:0030424^cellular_component^axon,GO:0043203^cellular_component^axon hillock,GO:0005604^cellular_component^basement membrane,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0030424^cellular_component^axon,GO:0043203^cellular_component^axon hillock,GO:0005604^cellular_component^basement membrane,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,KEGG:mmu:20317`KO:K19614,COG4826^serine-type endopeptidase inhibitor activity,PF00079.20^Serpin^Serpin (serine protease inhibitor)^56-414^E:1.7e-88,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i3,DN13693_c0_g1,RP9_HUMAN,Retinitis pigmentosa 9 protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:6100`KO:K19604,ENOG4111TFK^Retinitis pigmentosa 9 (Autosomal dominant),.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i1,DN13693_c0_g1,RP9_HUMAN,Retinitis pigmentosa 9 protein,RP9_HUMAN,Retinitis pigmentosa 9 protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:6100`KO:K19604,ENOG4111TFK^Retinitis pigmentosa 9 (Autosomal dominant),.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i7,DN13693_c0_g1,RP9_HUMAN,Retinitis pigmentosa 9 protein,RP9_HUMAN,Retinitis pigmentosa 9 protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:6100`KO:K19604,ENOG4111TFK^Retinitis pigmentosa 9 (Autosomal dominant),.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i6,DN13693_c0_g1,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,KEGG:mmu:55934`KO:K19604,"ENOG410ZVMR^corepressor interacting with RBPJ, 1",.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i9,DN13693_c0_g1,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,KEGG:mmu:55934`KO:K19604,"ENOG410ZVMR^corepressor interacting with RBPJ, 1",.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i4,DN13693_c0_g1,RP9_HUMAN,Retinitis pigmentosa 9 protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:6100`KO:K19604,ENOG4111TFK^Retinitis pigmentosa 9 (Autosomal dominant),.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i5,DN13693_c0_g1,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,.,NA,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,.,NA,NA,NA,NA,KEGG:mmu:55934`KO:K19604,"ENOG410ZVMR^corepressor interacting with RBPJ, 1",.,NA,NA,NA,NA,,
no,MJ,IgM,DN13693_c0_g1_i2,DN13693_c0_g1,RP9_HUMAN,Retinitis pigmentosa 9 protein,RP9_MOUSE,Retinitis pigmentosa 9 protein homolog,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005785^cellular_component^signal recognition particle receptor complex,GO:0046872^molecular_function^metal ion binding,GO:0003723^molecular_function^RNA binding,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0050890^biological_process^cognition,KEGG:mmu:55934`KO:K19604,"ENOG410ZVMR^corepressor interacting with RBPJ, 1",.,NA,NA,NA,NA,,
no,MJ,IgM,DN28086_c0_g1_i4,DN28086_c0_g1,AP3S1_MOUSE,AP-3 complex subunit sigma-1,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN28086_c0_g1_i2,DN28086_c0_g1,AP3S1_MOUSE,AP-3 complex subunit sigma-1,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN28086_c0_g1_i3,DN28086_c0_g1,AP3S1_MOUSE,AP-3 complex subunit sigma-1,.,NA,GO:0030123^cellular_component^AP-3 adaptor complex,GO:1904115^cellular_component^axon cytoplasm,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:mmu:11777`KO:K12399,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
no,MJ,IgM,DN5364_c0_g1_i3,DN5364_c0_g1,PIGM_CHICK,GPI mannosyltransferase 1,PIGM_CHICK,GPI mannosyltransferase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016758^molecular_function^transferase activity, transferring hexosyl groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016758^molecular_function^transferase activity, transferring hexosyl groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,KEGG:gga:428583`KO:K05284,ENOG410XRDY^Mannosyltransferase,PF06728.13^PIG-U^GPI transamidase subunit PIG-U^59-381^E:4.2e-16,PF05007.13^Mannosyl_trans^Mannosyltransferase (PIG-M)^148-423^E:7.1e-100,NA,NA,NA,,
no,MJ,IgM,DN5364_c0_g1_i4,DN5364_c0_g1,PIGM_CHICK,GPI mannosyltransferase 1,PIGM_CHICK,GPI mannosyltransferase 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016758^molecular_function^transferase activity, transferring hexosyl groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0016758^molecular_function^transferase activity, transferring hexosyl groups",GO:0006506^biological_process^GPI anchor biosynthetic process,NA,KEGG:gga:428583`KO:K05284,ENOG410XRDY^Mannosyltransferase,PF06728.13^PIG-U^GPI transamidase subunit PIG-U^59-381^E:6.3e-16,PF05007.13^Mannosyl_trans^Mannosyltransferase (PIG-M)^148-423^E:9.4e-100,NA,NA,NA,,
no,MJ,IgM,DN1685_c1_g2_i2,DN1685_c1_g2,SGMR1_CHICK,Sigma non-opioid intracellular receptor 1,SGMR1_CHICK,Sigma non-opioid intracellular receptor 1,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,KEGG:gga:100859748`KO:K20719,.,PF04622.12^ERG2_Sigma1R^ERG2 and Sigma1 receptor like protein^27-222^E:2.1e-68,NA,NA,NA,NA,,
no,MJ,IgM,DN404021_c0_g1_i1,DN404021_c0_g1,AP4S1_HUMAN,AP-4 complex subunit sigma-1 {ECO:0000305},.,NA,GO:0030124^cellular_component^AP-4 adaptor complex,GO:0031904^cellular_component^endosome lumen,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0032588^cellular_component^trans-Golgi network membrane,GO:0008104^biological_process^protein localization,.,NA,NA,NA,NA,KEGG:hsa:11154`KO:K12403,COG5030^Adaptor-related protein complex,.,NA,NA,NA,NA,,
yes,JO,IL10,DN186640_c0_g2_i4,DN186640_c0_g2,IL10_CHICK,Interleukin-10,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,.,NA,NA,NA,NA,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,.,NA,NA,NA,NA,,
yes,JO,IL10,DN186640_c0_g2_i2,DN186640_c0_g2,IL10_CHICK,Interleukin-10,IL10_CHICK,Interleukin-10,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,PF00726.17^IL10^Interleukin 10^49-175^E:7.6e-41,PF14565.6^IL22^Interleukin 22 IL-10-related T-cell-derived-inducible factor^60-172^E:5.1e-09,NA,NA,NA,,
yes,JO,IL10,DN186640_c0_g2_i5,DN186640_c0_g2,IL10_CHICK,Interleukin-10,IL10_CHICK,Interleukin-10,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,PF00726.17^IL10^Interleukin 10^1-106^E:1.6e-28,NA,NA,NA,NA,,
yes,JO,IL10,DN186640_c0_g2_i6,DN186640_c0_g2,IL10_CHICK,Interleukin-10,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,.,NA,NA,NA,NA,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,.,NA,NA,NA,NA,,
yes,JO,IL10,DN186640_c0_g2_i1,DN186640_c0_g2,IL10_CHICK,Interleukin-10,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,.,NA,NA,NA,NA,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,.,NA,NA,NA,NA,,
yes,JO,IL10,DN368828_c0_g1_i1,DN368828_c0_g1,IL10_CHICK,Interleukin-10,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0046983^molecular_function^protein dimerization activity,GO:0035729^biological_process^cellular response to hepatocyte growth factor stimulus,.,NA,NA,NA,NA,KEGG:gga:428264`KO:K05443,ENOG4111PXC^Interleukin 10,.,NA,NA,NA,NA,,
yes,JO,IL12,DN59329_c0_g1_i1,DN59329_c0_g1,IL12B_MARMO,Interleukin-12 subunit beta,IL12B_MARMO,Interleukin-12 subunit beta,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005125^molecular_function^cytokine activity,GO:0004896^molecular_function^cytokine receptor activity,NA,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005125^molecular_function^cytokine activity,GO:0004896^molecular_function^cytokine receptor activity,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,IL12,DN51560_c0_g2_i1,DN51560_c0_g2,IL12A_PIG,Interleukin-12 subunit alpha,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005143^molecular_function^interleukin-12 receptor binding,GO:0006955^biological_process^immune response,.,NA,NA,NA,NA,KEGG:ssc:397053`KO:K05406,"ENOG410ZGHJ^Interleukin 12A (Natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)",.,NA,NA,NA,NA,,
yes,JO,IL12,DN267130_c0_g1_i1,DN267130_c0_g1,IL12B_SHEEP,Interleukin-12 subunit beta,.,NA,GO:0005615^cellular_component^extracellular space,GO:0043514^cellular_component^interleukin-12 complex,GO:0016020^cellular_component^membrane,GO:0005125^molecular_function^cytokine activity,GO:0004896^molecular_function^cytokine receptor activity,.,NA,NA,NA,NA,KEGG:oas:443472`KO:K05425,.,.,NA,NA,NA,NA,,
yes,JO,IL12,DN288619_c0_g1_i1,DN288619_c0_g1,IL12B_FELCA,Interleukin-12 subunit beta,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0043235^cellular_component^receptor complex,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:fca:768273`KO:K05425,"ENOG410YWXR^interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)",.,NA,NA,NA,NA,,
yes,JO,IL17,DN2937_c0_g1_i8,DN2937_c0_g1,PCYXL_HUMAN,Prenylcysteine oxidase-like,IL17B_MOUSE,Interleukin-17B,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0001735^molecular_function^prenylcysteine oxidase activity,GO:0002576^biological_process^platelet degranulation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0006954^biological_process^inflammatory response,GO:0030593^biological_process^neutrophil chemotaxis,KEGG:mmu:56069`KO:K05490,ENOG410ZKTD^interleukin 17B,.,NA,NA,NA,NA,,
yes,JO,IL17,DN2937_c0_g1_i11,DN2937_c0_g1,PCYXL_HUMAN,Prenylcysteine oxidase-like,IL17B_MOUSE,Interleukin-17B,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0031093^cellular_component^platelet alpha granule lumen,GO:0001735^molecular_function^prenylcysteine oxidase activity,GO:0002576^biological_process^platelet degranulation,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0006954^biological_process^inflammatory response,GO:0030593^biological_process^neutrophil chemotaxis,KEGG:mmu:56069`KO:K05490,ENOG410ZKTD^interleukin 17B,.,NA,NA,NA,NA,,
yes,JO,IL17,DN69135_c0_g1_i1,DN69135_c0_g1,IL17C_HUMAN,Interleukin-17C,IL17C_HUMAN,Interleukin-17C,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0007267^biological_process^cell-cell signaling,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0007166^biological_process^cell surface receptor signaling pathway,GO:0007267^biological_process^cell-cell signaling,KEGG:hsa:27189`KO:K05491,ENOG4111VTD^interleukin,PF06083.11^IL17^Interleukin-17^123-207^E:2.3e-29,NA,NA,NA,NA,,
yes,JO,IL17,DN124002_c0_g1_i1,DN124002_c0_g1,IL17F_RAT,Interleukin-17F,IL17F_RAT,Interleukin-17F,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0006954^biological_process^inflammatory response,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0006954^biological_process^inflammatory response,NA,NA,KEGG:rno:301291`KO:K05494,ENOG410YVBI^Interleukin 17F,PF06083.11^IL17^Interleukin-17^97-153^E:2.9e-20,NA,NA,NA,NA,,
yes,JO,IL17,DN126876_c0_g1_i1,DN126876_c0_g1,IL17D_HUMAN,Interleukin-17D,IL17D_HUMAN,Interleukin-17D,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0048018^molecular_function^receptor ligand activity,GO:0006954^biological_process^inflammatory response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0048018^molecular_function^receptor ligand activity,GO:0006954^biological_process^inflammatory response,KEGG:hsa:53342`KO:K05492,ENOG4112BXJ^interleukin 17D,PF06083.11^IL17^Interleukin-17^153-234^E:2.5e-27,NA,NA,NA,NA,,
yes,JO,IL17,DN108801_c0_g1_i1,DN108801_c0_g1,IL17F_RAT,Interleukin-17F,IL17F_RAT,Interleukin-17F,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0006954^biological_process^inflammatory response,NA,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0006954^biological_process^inflammatory response,NA,NA,KEGG:rno:301291`KO:K05494,ENOG410YVBI^Interleukin 17F,PF06083.11^IL17^Interleukin-17^99-176^E:4e-30,NA,NA,NA,NA,,
yes,JO,IL17,DN346699_c0_g1_i1,DN346699_c0_g1,IL17B_MOUSE,Interleukin-17B,IL17B_MOUSE,Interleukin-17B,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0006954^biological_process^inflammatory response,GO:0030593^biological_process^neutrophil chemotaxis,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0005102^molecular_function^signaling receptor binding,GO:0006954^biological_process^inflammatory response,GO:0030593^biological_process^neutrophil chemotaxis,KEGG:mmu:56069`KO:K05490,ENOG410ZKTD^interleukin 17B,PF06083.11^IL17^Interleukin-17^36-128^E:4.2e-30,NA,NA,NA,NA,,
yes,JO,IL18,DN76285_c0_g1_i1,DN76285_c0_g1,IL18_CHICK,Interleukin-18,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,.,NA,NA,NA,NA,.,ENOG410ZGS8^interleukin 18 (interferon-gamma-inducing factor),.,NA,NA,NA,NA,,
yes,JO,IL18,DN12243_c0_g1_i1,DN12243_c0_g1,IL18_CHICK,Interleukin-18,IL18_CHICK,Interleukin-18,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,.,ENOG410ZGS8^interleukin 18 (interferon-gamma-inducing factor),PF00340.19^IL1^Interleukin-1 / 18^2-109^E:4.9e-12,NA,NA,NA,NA,,
yes,JO,IL18,DN12243_c0_g1_i5,DN12243_c0_g1,IL18_CHICK,Interleukin-18,IL18_CHICK,Interleukin-18,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,.,ENOG410ZGS8^interleukin 18 (interferon-gamma-inducing factor),PF00340.19^IL1^Interleukin-1 / 18^18-126^E:4.2e-12,NA,NA,NA,NA,,
yes,JO,IL18,DN12243_c0_g1_i7,DN12243_c0_g1,IL18_CHICK,Interleukin-18,IL18_CHICK,Interleukin-18,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,.,ENOG410ZGS8^interleukin 18 (interferon-gamma-inducing factor),.,NA,NA,NA,NA,,
yes,JO,IL18,DN12243_c0_g1_i2,DN12243_c0_g1,IL18_CHICK,Interleukin-18,IL18_CHICK,Interleukin-18,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,"GO:0035710^biological_process^CD4-positive, alpha-beta T cell activation",GO:0006955^biological_process^immune response,GO:0006954^biological_process^inflammatory response,.,ENOG410ZGS8^interleukin 18 (interferon-gamma-inducing factor),PF00340.19^IL1^Interleukin-1 / 18^75-183^E:1.2e-11,NA,NA,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i11,DN599_c0_g1,IL18R_HUMAN,Interleukin-18 receptor 1,ILRL1_MOUSE,Interleukin-1 receptor-like 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,KEGG:mmu:17082`KO:K05171,ENOG4110Z8K^Interleukin 1 receptor accessory protein-like,PF00047.25^ig^Immunoglobulin domain^20-95^E:1.2e-05,PF18452.1^Ig_6^Immunoglobulin domain^61-112^E:3.6e-10,PF13895.6^Ig_2^Immunoglobulin domain^127-188^E:1.4e-06,PF00047.25^ig^Immunoglobulin domain^215-312^E:5.9e-06,PF07679.16^I-set^Immunoglobulin I-set domain^216-314^E:1.2e-05,,
yes,JO,IL18,DN599_c0_g1_i3,DN599_c0_g1,IL18R_HUMAN,Interleukin-18 receptor 1,IL18R_HUMAN,Interleukin-18 receptor 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,PF01582.20^TIR^TIR domain^3-129^E:1.8e-34,PF13676.6^TIR_2^TIR domain^5-74^E:3e-07,NA,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i5,DN599_c0_g1,ILRL1_MOUSE,Interleukin-1 receptor-like 1,IL18R_HUMAN,Interleukin-18 receptor 1,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,PF13895.6^Ig_2^Immunoglobulin domain^135-202^E:2.6e-07,NA,NA,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i21,DN599_c0_g1,IL18R_HUMAN,Interleukin-18 receptor 1,IL18R_HUMAN,Interleukin-18 receptor 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,PF13895.6^Ig_2^Immunoglobulin domain^135-202^E:4.7e-07,PF01582.20^TIR^TIR domain^385-538^E:6.1e-39,PF13676.6^TIR_2^TIR domain^386-482^E:1.2e-08,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i17,DN599_c0_g1,I18RA_HUMAN,Interleukin-18 receptor accessory protein,IL18R_HUMAN,Interleukin-18 receptor 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0008283^biological_process^cell population proliferation,GO:0070301^biological_process^cellular response to hydrogen peroxide,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,PF03231.13^Bunya_NS-S_2^Bunyavirus non-structural protein NS-S^69-173^E:0.00056,PF13895.6^Ig_2^Immunoglobulin domain^135-202^E:3.9e-07,PF01582.20^TIR^TIR domain^385-445^E:1.5e-09,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i14,DN599_c0_g1,IL18R_HUMAN,Interleukin-18 receptor 1,ILRL1_MOUSE,Interleukin-1 receptor-like 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,KEGG:mmu:17082`KO:K05171,ENOG4110Z8K^Interleukin 1 receptor accessory protein-like,PF00047.25^ig^Immunoglobulin domain^20-95^E:1.2e-05,PF18452.1^Ig_6^Immunoglobulin domain^61-112^E:3.6e-10,PF13895.6^Ig_2^Immunoglobulin domain^127-188^E:1.4e-06,PF00047.25^ig^Immunoglobulin domain^215-312^E:5.9e-06,PF07679.16^I-set^Immunoglobulin I-set domain^216-314^E:1.2e-05,,
yes,JO,IL18,DN599_c0_g1_i18,DN599_c0_g1,I18RA_HUMAN,Interleukin-18 receptor accessory protein,IL18R_HUMAN,Interleukin-18 receptor 1,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0042008^molecular_function^interleukin-18 receptor activity,GO:0008283^biological_process^cell population proliferation,GO:0070301^biological_process^cellular response to hydrogen peroxide,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,PF03231.13^Bunya_NS-S_2^Bunyavirus non-structural protein NS-S^69-173^E:0.00056,PF13895.6^Ig_2^Immunoglobulin domain^135-202^E:3.9e-07,PF01582.20^TIR^TIR domain^385-445^E:1.5e-09,NA,NA,,
yes,JO,IL18,DN599_c0_g1_i13,DN599_c0_g1,IL18R_HUMAN,Interleukin-18 receptor 1,.,NA,GO:0045092^cellular_component^interleukin-18 receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0004908^molecular_function^interleukin-1 receptor activity,GO:0042007^molecular_function^interleukin-18 binding,GO:0042008^molecular_function^interleukin-18 receptor activity,.,NA,NA,NA,NA,KEGG:hsa:8809`KO:K05173,ENOG410ZKHN^Interleukin 18 receptor 1,.,NA,NA,NA,NA,,
yes,JO,IL22,DN57056_c0_g2_i2,DN57056_c0_g2,IL22_HUMAN,Interleukin-22,IL22_HUMAN,Interleukin-22,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0045518^molecular_function^interleukin-22 receptor binding,GO:0006953^biological_process^acute-phase response,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0045518^molecular_function^interleukin-22 receptor binding,GO:0006953^biological_process^acute-phase response,KEGG:hsa:50616`KO:K05445,ENOG4112217^Interleukin 22,PF14565.6^IL22^Interleukin 22 IL-10-related T-cell-derived-inducible factor^46-184^E:1.6e-76,PF00726.17^IL10^Interleukin 10^52-183^E:4.5e-06,NA,NA,NA,,
yes,JO,IL22,DN57056_c0_g2_i3,DN57056_c0_g2,IL22B_MOUSE,Interleukin-22b,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:116849,ENOG4112217^Interleukin 22,.,NA,NA,NA,NA,,
yes,JO,IL6,DN73360_c0_g1_i4,DN73360_c0_g1,IL6_CHICK,Interleukin-6,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005138^molecular_function^interleukin-6 receptor binding,GO:0006953^biological_process^acute-phase response,.,NA,NA,NA,NA,KEGG:gga:395337`KO:K05405,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN73360_c0_g1_i5,DN73360_c0_g1,IL6_CHICK,Interleukin-6,IL6_CHICK,Interleukin-6,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005138^molecular_function^interleukin-6 receptor binding,GO:0006953^biological_process^acute-phase response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005138^molecular_function^interleukin-6 receptor binding,GO:0006953^biological_process^acute-phase response,KEGG:gga:395337`KO:K05405,.,PF16647.5^GCSF^Granulocyte colony-stimulating factor^1-95^E:3.3e-07,PF00489.17^IL6^Interleukin-6/G-CSF/MGF family^2-147^E:4e-48,NA,NA,NA,,
yes,JO,IL6,DN73360_c0_g1_i2,DN73360_c0_g1,IL6_CHICK,Interleukin-6,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005138^molecular_function^interleukin-6 receptor binding,GO:0006953^biological_process^acute-phase response,.,NA,NA,NA,NA,KEGG:gga:395337`KO:K05405,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10250_c1_g1_i14,DN10250_c1_g1,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:16195`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^461-543^E:3.5e-12,NA,NA,NA,NA,,
yes,JO,IL6,DN10250_c1_g1_i18,DN10250_c1_g1,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)","PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^81-118^E:1.8e-05",PF00041.21^fn3^Fibronectin type III domain^175-247^E:1.5e-05,NA,NA,NA,,
yes,JO,IL6,DN10250_c1_g1_i17,DN10250_c1_g1,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:16195`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^169-251^E:2.4e-12,NA,NA,NA,NA,,
yes,JO,IL6,DN10250_c1_g1_i11,DN10250_c1_g1,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:16195`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)","PF09240.10^IL6Ra-bind^Interleukin-6 receptor alpha chain, binding^81-118^E:3.4e-05",PF00041.21^fn3^Fibronectin type III domain^461-543^E:3.1e-12,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i1,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF06328.11^Lep_receptor_Ig^Ig-like C2-type domain^29-115^E:7e-29,PF00041.21^fn3^Fibronectin type III domain^229-315^E:2e-08,PF00041.21^fn3^Fibronectin type III domain^531-605^E:3.5e-09,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i4,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",.,NA,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i7,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^58-133^E:3.4e-10,NA,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i8,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",.,NA,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i3,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^175-249^E:1.8e-09,NA,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i6,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^4-59^E:1.9e-06,PF00041.21^fn3^Fibronectin type III domain^275-349^E:2.3e-09,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g1_i2,DN11302_c1_g1,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",.,NA,NA,NA,NA,,
yes,JO,IL6,DN11302_c1_g2_i1,DN11302_c1_g2,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,IL6RB_HUMAN,Interleukin-6 receptor subunit beta,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3572`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF00041.21^fn3^Fibronectin type III domain^5-91^E:2.4e-10,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i2,DN10585_c0_g1,.,NA,IL6RA_HUMAN,Interleukin-6 receptor subunit alpha,.,NA,NA,NA,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3570`KO:K05055,ENOG4111XGC^Interleukin 6 receptor,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i7,DN10585_c0_g1,IL6RA_PIG,Interleukin-6 receptor subunit alpha,IL6RA_PIG,Interleukin-6 receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,KEGG:ssc:399522`KO:K05055,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i3,DN10585_c0_g1,IL6RA_PIG,Interleukin-6 receptor subunit alpha,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:ssc:399522`KO:K05055,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i6,DN10585_c0_g1,IL6RA_PIG,Interleukin-6 receptor subunit alpha,IL6RA_PIG,Interleukin-6 receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,KEGG:ssc:399522`KO:K05055,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i5,DN10585_c0_g1,IL6RA_PIG,Interleukin-6 receptor subunit alpha,.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,.,NA,NA,NA,NA,KEGG:ssc:399522`KO:K05055,.,.,NA,NA,NA,NA,,
yes,JO,IL6,DN10585_c0_g1_i1,DN10585_c0_g1,IL6RA_PIG,Interleukin-6 receptor subunit alpha,IL6RA_HUMAN,Interleukin-6 receptor subunit alpha,GO:0009897^cellular_component^external side of plasma membrane,GO:0043514^cellular_component^interleukin-12 complex,GO:0070743^cellular_component^interleukin-23 complex,GO:0005896^cellular_component^interleukin-6 receptor complex,GO:0043235^cellular_component^receptor complex,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3570`KO:K05055,ENOG4111XGC^Interleukin 6 receptor,.,NA,NA,NA,NA,,
yes,JO,IL6,DN9881_c0_g2_i5,DN9881_c0_g2,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:16195`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF06328.11^Lep_receptor_Ig^Ig-like C2-type domain^27-101^E:6.7e-13,NA,NA,NA,NA,,
yes,JO,IL6,DN9881_c0_g2_i8,DN9881_c0_g2,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,IL6RB_MOUSE,Interleukin-6 receptor subunit beta,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0044297^cellular_component^cell body,GO:0070110^cellular_component^ciliary neurotrophic factor receptor complex,GO:0030425^cellular_component^dendrite,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,KEGG:mmu:16195`KO:K05060,"ENOG410YNQ4^interleukin 6 signal transducer (gp130, oncostatin M receptor)",PF06328.11^Lep_receptor_Ig^Ig-like C2-type domain^27-102^E:3e-13,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i11,DN67239_c0_g1,PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,KEGG:hsa:285755`KO:K12739,.,PF00160.21^Pro_isomerase^Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD^41-200^E:2.1e-43,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i4,DN67239_c0_g1,PPIL6_BOVIN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305},PPIL6_BOVIN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305},GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,KEGG:bta:614498`KO:K12739,COG0652^peptidyl-prolyl cis-trans isomerase activity,PF00160.21^Pro_isomerase^Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD^56-196^E:1.3e-34,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i2,DN67239_c0_g1,PPIL6_BOVIN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305},PPIL6_BOVIN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305},GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,KEGG:bta:614498`KO:K12739,COG0652^peptidyl-prolyl cis-trans isomerase activity,PF00160.21^Pro_isomerase^Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD^56-217^E:1.7e-43,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i12,DN67239_c0_g1,PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},.,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,.,NA,NA,NA,NA,KEGG:hsa:285755`KO:K12739,.,.,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i8,DN67239_c0_g1,PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},.,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,.,NA,NA,NA,NA,KEGG:hsa:285755`KO:K12739,.,.,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g1_i6,DN67239_c0_g1,PPIL6_BOVIN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305},.,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,.,NA,NA,NA,NA,KEGG:bta:614498`KO:K12739,COG0652^peptidyl-prolyl cis-trans isomerase activity,.,NA,NA,NA,NA,,
no,AD,IL6,DN67239_c0_g2_i1,DN67239_c0_g2,PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},PPIL6_HUMAN,Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357},GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,GO:0016018^molecular_function^cyclosporin A binding,GO:0003755^molecular_function^peptidyl-prolyl cis-trans isomerase activity,GO:0051082^molecular_function^unfolded protein binding,GO:0042026^biological_process^protein refolding,NA,KEGG:hsa:285755`KO:K12739,.,PF00160.21^Pro_isomerase^Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD^62-122^E:2.3e-11,NA,NA,NA,NA,,
yes,JO,IL6,DN431799_c0_g1_i1,DN431799_c0_g1,IL6_CHICK,Interleukin-6,.,NA,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005138^molecular_function^interleukin-6 receptor binding,GO:0006953^biological_process^acute-phase response,.,NA,NA,NA,NA,KEGG:gga:395337`KO:K05405,.,.,NA,NA,NA,NA,,
yes,JO,IL8,DN861_c0_g1_i2,DN861_c0_g1,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^31-90^E:7.4e-15",NA,NA,NA,NA,,
yes,JO,IL8,DN861_c0_g1_i1,DN861_c0_g1,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^31-90^E:7.4e-15",NA,NA,NA,NA,,
yes,JO,IL8,DN23713_c0_g1_i2,DN23713_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN31594_c0_g1_i5,DN31594_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN31594_c0_g1_i4,DN31594_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN7951_c0_g1_i8,DN7951_c0_g1,IL8H_GAHVM,Viral interleukin-8 homolog,.,NA,GO:0005576^cellular_component^extracellular region,GO:0008009^molecular_function^chemokine activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0006952^biological_process^defense response,GO:0030683^biological_process^evasion or tolerance by virus of host immune response,.,NA,NA,NA,NA,KEGG:vg:4811462`KEGG:vg:4811544`KO:K22625,.,.,NA,NA,NA,NA,,
yes,JO,IL8,DN7951_c0_g1_i2,DN7951_c0_g1,IL8H_GAHVM,Viral interleukin-8 homolog,.,NA,GO:0005576^cellular_component^extracellular region,GO:0008009^molecular_function^chemokine activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0006952^biological_process^defense response,GO:0030683^biological_process^evasion or tolerance by virus of host immune response,.,NA,NA,NA,NA,KEGG:vg:4811462`KEGG:vg:4811544`KO:K22625,.,.,NA,NA,NA,NA,,
yes,JO,IL8,DN7951_c0_g1_i3,DN7951_c0_g1,IL8H_GAHVM,Viral interleukin-8 homolog,.,NA,GO:0005576^cellular_component^extracellular region,GO:0008009^molecular_function^chemokine activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0006952^biological_process^defense response,GO:0030683^biological_process^evasion or tolerance by virus of host immune response,.,NA,NA,NA,NA,KEGG:vg:4811462`KEGG:vg:4811544`KO:K22625,.,.,NA,NA,NA,NA,,
yes,JO,IL8,DN7951_c0_g1_i6,DN7951_c0_g1,IL8H_GAHVM,Viral interleukin-8 homolog,IL8H_GAHVM,Viral interleukin-8 homolog,GO:0005576^cellular_component^extracellular region,GO:0008009^molecular_function^chemokine activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0006952^biological_process^defense response,GO:0030683^biological_process^evasion or tolerance by virus of host immune response,GO:0005576^cellular_component^extracellular region,GO:0008009^molecular_function^chemokine activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0006952^biological_process^defense response,GO:0030683^biological_process^evasion or tolerance by virus of host immune response,KEGG:vg:4811462`KEGG:vg:4811544`KO:K22625,.,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^77-136^E:4.5e-12",NA,NA,NA,NA,,
yes,JO,IL8,DN89028_c0_g2_i1,DN89028_c0_g2,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^60-118^E:7.7e-16",NA,NA,NA,NA,,
yes,JO,IL8,DN89028_c0_g2_i2,DN89028_c0_g2,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^60-118^E:6.5e-16",NA,NA,NA,NA,,
yes,JO,IL8,DN6496_c0_g1_i3,DN6496_c0_g1,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^32-90^E:3e-18",NA,NA,NA,NA,,
yes,JO,IL8,DN6496_c0_g1_i4,DN6496_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN6496_c0_g1_i2,DN6496_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN6496_c0_g1_i1,DN6496_c0_g1,IL8_CHICK,Interleukin-8,.,NA,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,.,NA,NA,NA,NA,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus",.,NA,NA,NA,NA,,
yes,JO,IL8,DN238344_c0_g1_i1,DN238344_c0_g1,IL8_CHICK,Interleukin-8,IL8_CHICK,Interleukin-8,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,GO:0005615^cellular_component^extracellular space,GO:0008009^molecular_function^chemokine activity,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005153^molecular_function^interleukin-8 receptor binding,KEGG:gga:396495`KO:K10030,"ENOG410Z1BP^IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus","PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^32-90^E:1.7e-13",NA,NA,NA,NA,,
yes,JO,INHB,DN7922_c0_g1_i1,DN7922_c0_g1,INHBB_CHICK,Inhibin beta B chain,INHBB_CHICK,Inhibin beta B chain,GO:0005615^cellular_component^extracellular space,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,GO:0005615^cellular_component^extracellular space,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,KEGG:gga:396126`KO:K22687,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^161-365^E:7.3e-10,PF00019.20^TGF_beta^Transforming growth factor beta like domain^390-494^E:2e-28,NA,NA,NA,,
yes,JO,INHB,DN7922_c0_g1_i2,DN7922_c0_g1,INHBB_CHICK,Inhibin beta B chain,INHBB_CHICK,Inhibin beta B chain,GO:0005615^cellular_component^extracellular space,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,GO:0005615^cellular_component^extracellular space,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005179^molecular_function^hormone activity,KEGG:gga:396126`KO:K22687,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^75-195^E:1.8e-05,PF00019.20^TGF_beta^Transforming growth factor beta like domain^220-324^E:9.3e-29,NA,NA,NA,,
yes,JO,INHB,DN2585_c0_g2_i1,DN2585_c0_g2,INHBA_CHICK,Inhibin beta A chain,INHBA_CHICK,Inhibin beta A chain,GO:0043509^cellular_component^activin A complex,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043512^cellular_component^inhibin A complex,GO:0005125^molecular_function^cytokine activity,GO:0043509^cellular_component^activin A complex,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043512^cellular_component^inhibin A complex,GO:0005125^molecular_function^cytokine activity,KEGG:gga:396361`KO:K04667,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^51-292^E:2.7e-09,PF00019.20^TGF_beta^Transforming growth factor beta like domain^319-423^E:1.6e-30,NA,NA,NA,,
yes,JO,INHB,DN345138_c0_g1_i1,DN345138_c0_g1,INHBA_CHICK,Inhibin beta A chain,.,NA,GO:0043509^cellular_component^activin A complex,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043512^cellular_component^inhibin A complex,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:gga:396361`KO:K04667,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,JO,interferon,DN28863_c0_g1_i1,DN28863_c0_g1,IFM10_MOUSE,Interferon-induced transmembrane protein 10,IFM10_MOUSE,Interferon-induced transmembrane protein 10,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,NA,NA,NA,KEGG:mmu:320802`KO:K06566,ENOG41114HW^Interferon induced transmembrane protein 10,PF04505.12^CD225^Interferon-induced transmembrane protein^64-129^E:3.8e-21,NA,NA,NA,NA,,
yes,JO,interferon,DN62_c1_g1_i5,DN62_c1_g1,IRF5_HUMAN,Interferon regulatory factor 5,IRF5_HUMAN,Interferon regulatory factor 5,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:hsa:3663`KO:K09446,ENOG410XRXT^interferon regulatory factor,PF10401.9^IRF-3^Interferon-regulatory factor 3^111-292^E:3.6e-71,NA,NA,NA,NA,,
yes,JO,interferon,DN62_c1_g1_i6,DN62_c1_g1,IRF5_HUMAN,Interferon regulatory factor 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:hsa:3663`KO:K09446,ENOG410XRXT^interferon regulatory factor,.,NA,NA,NA,NA,,
yes,JO,interferon,DN62_c1_g1_i1,DN62_c1_g1,IRF5_HUMAN,Interferon regulatory factor 5,IRF5_HUMAN,Interferon regulatory factor 5,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:hsa:3663`KO:K09446,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^9-114^E:4e-41,NA,NA,NA,NA,,
yes,JO,interferon,DN62_c1_g1_i2,DN62_c1_g1,IRF5_BOVIN,Interferon regulatory factor 5,IRF5_HUMAN,Interferon regulatory factor 5,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:hsa:3663`KO:K09446,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^9-114^E:8.4e-40,PF10401.9^IRF-3^Interferon-regulatory factor 3^252-433^E:7.8e-71,NA,NA,NA,,
yes,JO,interferon,DN69_c0_g1_i5,DN69_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN69_c16_g1_i1,DN69_c16_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN95_c0_g1_i3,DN95_c0_g1,I20L2_HUMAN,Interferon-stimulated 20 kDa exonuclease-like 2,I20L2_RAT,Interferon-stimulated 20 kDa exonuclease-like 2,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0003676^molecular_function^nucleic acid binding,KEGG:rno:361977`KO:K18329,COG0847^DNA polymerase iii,PF00929.24^RNase_T^Exonuclease^27-182^E:7.8e-12,NA,NA,NA,NA,,
yes,JO,interferon,DN95_c0_g1_i1,DN95_c0_g1,I20L2_HUMAN,Interferon-stimulated 20 kDa exonuclease-like 2,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,.,NA,NA,NA,NA,KEGG:hsa:81875`KO:K18329,COG0847^DNA polymerase iii,.,NA,NA,NA,NA,,
yes,JO,interferon,DN95_c0_g1_i2,DN95_c0_g1,I20L2_RAT,Interferon-stimulated 20 kDa exonuclease-like 2,I20L2_RAT,Interferon-stimulated 20 kDa exonuclease-like 2,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0003676^molecular_function^nucleic acid binding,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0003676^molecular_function^nucleic acid binding,KEGG:rno:361977`KO:K18329,COG0847^DNA polymerase iii,PF00929.24^RNase_T^Exonuclease^87-242^E:1.1e-11,NA,NA,NA,NA,,
yes,JO,interferon,DN95_c0_g1_i4,DN95_c0_g1,I20L2_RAT,Interferon-stimulated 20 kDa exonuclease-like 2,I20L2_RAT,Interferon-stimulated 20 kDa exonuclease-like 2,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0003676^molecular_function^nucleic acid binding,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000175^molecular_function^3'-5'-exoribonuclease activity,GO:0004527^molecular_function^exonuclease activity,GO:0003676^molecular_function^nucleic acid binding,KEGG:rno:361977`KO:K18329,COG0847^DNA polymerase iii,PF00929.24^RNase_T^Exonuclease^80-235^E:1e-11,NA,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g1_i1,DN20681_c0_g1,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},.,NA,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,NA,NA,NA,NA,.,ENOG4111M85^transmembrane protein 173,.,NA,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g3_i1,DN20681_c0_g3,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,ENOG4111M85^transmembrane protein 173,PF15009.6^TMEM173^Transmembrane protein 173^52-140^E:1e-19,NA,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g3_i3,DN20681_c0_g3,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},.,NA,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,NA,NA,NA,NA,.,ENOG4111M85^transmembrane protein 173,.,NA,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g3_i2,DN20681_c0_g3,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,ENOG4111M85^transmembrane protein 173,PF15009.6^TMEM173^Transmembrane protein 173^52-177^E:2.6e-43,NA,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g3_i5,DN20681_c0_g3,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,ENOG4111M85^transmembrane protein 173,PF15009.6^TMEM173^Transmembrane protein 173^52-256^E:5.3e-76,PF15009.6^TMEM173^Transmembrane protein 173^256-320^E:1.3e-21,NA,NA,NA,,
yes,JO,interferon,DN20681_c0_g3_i4,DN20681_c0_g3,STING_CHICK,Stimulator of interferon genes protein {ECO:0000303|PubMed:30842659},.,NA,GO:0000421^cellular_component^autophagosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,.,NA,NA,NA,NA,.,ENOG4111M85^transmembrane protein 173,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3882_c0_g1_i4,DN3882_c0_g1,IRF2_CHICK,Interferon regulatory factor 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396115`KO:K10153,ENOG411152R^interferon regulatory factor 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3882_c0_g1_i3,DN3882_c0_g1,IRF2_CHICK,Interferon regulatory factor 2,IRF2_CHICK,Interferon regulatory factor 2,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:gga:396115`KO:K10153,ENOG411152R^interferon regulatory factor 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3882_c0_g1_i2,DN3882_c0_g1,IRF2_CHICK,Interferon regulatory factor 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005925^cellular_component^focal adhesion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396115`KO:K10153,ENOG411152R^interferon regulatory factor 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3852_c0_g1_i6,DN3852_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3852_c0_g1_i2,DN3852_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3852_c0_g1_i7,DN3852_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3852_c0_g1_i8,DN3852_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3852_c0_g1_i4,DN3852_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i4,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i5,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i10,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i7,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i2,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i8,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8768_c0_g1_i6,DN8768_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i15,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF00350.23^Dynamin_N^Dynamin family^146-219^E:9.4e-19,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i6,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF02212.18^GED^Dynamin GTPase effector domain^54-143^E:2.2e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i11,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i12,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF02212.18^GED^Dynamin GTPase effector domain^54-143^E:2.2e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i2,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,.,NA,NA,NA,NA,KEGG:apla:101793492`KO:K14754,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i13,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF00350.23^Dynamin_N^Dynamin family^4-52^E:6.1e-10,PF01031.20^Dynamin_M^Dynamin central region^65-281^E:6.4e-64,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i14,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF01031.20^Dynamin_M^Dynamin central region^2-153^E:8.4e-35,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i7,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,.,NA,NA,NA,NA,KEGG:apla:101793492`KO:K14754,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i5,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF00350.23^Dynamin_N^Dynamin family^4-52^E:1e-09,PF01031.20^Dynamin_M^Dynamin central region^65-349^E:6.2e-78,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i1,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF01031.20^Dynamin_M^Dynamin central region^2-221^E:8.4e-49,PF02212.18^GED^Dynamin GTPase effector domain^244-333^E:1.5e-22,NA,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i16,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,PF00350.23^Dynamin_N^Dynamin family^38-213^E:5.1e-49,PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^38-191^E:9.6e-05,PF01031.20^Dynamin_M^Dynamin central region^226-277^E:1.6e-19,NA,NA,,
yes,JO,interferon,DN2085_c0_g2_i10,DN2085_c0_g2,MX_ANAPL,Interferon-induced GTP-binding protein Mx,MX_ANAPL,Interferon-induced GTP-binding protein Mx,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,KEGG:apla:101793492`KO:K14754,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN43363_c0_g1_i1,DN43363_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7870_c0_g1_i1,DN7870_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN876_c0_g1_i4,DN876_c0_g1,E2AK2_HUMAN,"Interferon-induced, double-stranded RNA-activated protein kinase",E2AK2_RAT,"Interferon-induced, double-stranded RNA-activated protein kinase",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0022626^cellular_component^cytosolic ribosome,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0022626^cellular_component^cytosolic ribosome,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:rno:54287`KO:K16195,ENOG410XS0B^eukaryotic translation initiation factor 2alpha kinase,PF00035.26^dsrm^Double-stranded RNA binding motif^6-68^E:4e-17,PF00035.26^dsrm^Double-stranded RNA binding motif^106-171^E:3.1e-13,PF00069.25^Pkinase^Protein kinase domain^287-544^E:1.1e-52,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^290-546^E:7e-33,PF14531.6^Kinase-like^Kinase-like^379-491^E:8.8e-06,,
yes,JO,interferon,DN876_c0_g1_i7,DN876_c0_g1,E2AK2_HUMAN,"Interferon-induced, double-stranded RNA-activated protein kinase",E2AK2_RAT,"Interferon-induced, double-stranded RNA-activated protein kinase",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0022626^cellular_component^cytosolic ribosome,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0022626^cellular_component^cytosolic ribosome,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:rno:54287`KO:K16195,ENOG410XS0B^eukaryotic translation initiation factor 2alpha kinase,PF00035.26^dsrm^Double-stranded RNA binding motif^6-68^E:4e-17,PF00035.26^dsrm^Double-stranded RNA binding motif^106-171^E:3.1e-13,PF00069.25^Pkinase^Protein kinase domain^287-544^E:1.1e-52,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^290-546^E:7e-33,PF14531.6^Kinase-like^Kinase-like^379-491^E:8.8e-06,,
yes,JO,interferon,DN876_c0_g1_i1,DN876_c0_g1,E2AK2_RAT,"Interferon-induced, double-stranded RNA-activated protein kinase",E2AK2_RAT,"Interferon-induced, double-stranded RNA-activated protein kinase",GO:0005737^cellular_component^cytoplasm,GO:0022626^cellular_component^cytosolic ribosome,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0022626^cellular_component^cytosolic ribosome,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:rno:54287`KO:K16195,ENOG410XS0B^eukaryotic translation initiation factor 2alpha kinase,PF00035.26^dsrm^Double-stranded RNA binding motif^1-31^E:7.3e-06,PF00069.25^Pkinase^Protein kinase domain^96-350^E:1.4e-51,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^99-352^E:1.1e-32,PF14531.6^Kinase-like^Kinase-like^187-297^E:8.5e-06,NA,,
yes,JO,interferon,DN5174_c0_g1_i5,DN5174_c0_g1,INAR2_HUMAN,Interferon alpha/beta receptor 2,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,.,NA,NA,NA,NA,KEGG:hsa:3455`KO:K05131,"ENOG410YTXY^interferon (alpha, beta and omega) receptor 2",.,NA,NA,NA,NA,,
yes,JO,interferon,DN5174_c0_g1_i1,DN5174_c0_g1,.,NA,INAR2_HUMAN,Interferon alpha/beta receptor 2,.,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3455`KO:K05131,"ENOG410YTXY^interferon (alpha, beta and omega) receptor 2",.,NA,NA,NA,NA,,
yes,JO,interferon,DN5174_c0_g1_i8,DN5174_c0_g1,INAR2_HUMAN,Interferon alpha/beta receptor 2,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,.,NA,NA,NA,NA,KEGG:hsa:3455`KO:K05131,"ENOG410YTXY^interferon (alpha, beta and omega) receptor 2",.,NA,NA,NA,NA,,
yes,JO,interferon,DN5174_c0_g1_i11,DN5174_c0_g1,INAR2_HUMAN,Interferon alpha/beta receptor 2,INAR2_HUMAN,Interferon alpha/beta receptor 2,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3455`KO:K05131,"ENOG410YTXY^interferon (alpha, beta and omega) receptor 2","PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^56-160^E:6.7e-19",NA,NA,NA,NA,,
yes,JO,interferon,DN5174_c0_g1_i16,DN5174_c0_g1,INAR2_HUMAN,Interferon alpha/beta receptor 2,I22R1_HUMAN,Interleukin-22 receptor subunit alpha-1,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0004904^molecular_function^interferon receptor activity,GO:0042015^molecular_function^interleukin-20 binding,KEGG:hsa:58985`KO:K05138,"ENOG4111CQU^interleukin 22 receptor, alpha 1",PF01108.17^Tissue_fac^Tissue factor^17-113^E:2.8e-22,NA,NA,NA,NA,,
yes,JO,interferon,DN5174_c0_g1_i12,DN5174_c0_g1,.,NA,INAR2_HUMAN,Interferon alpha/beta receptor 2,.,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3455`KO:K05131,"ENOG410YTXY^interferon (alpha, beta and omega) receptor 2",.,NA,NA,NA,NA,,
yes,JO,interferon,DN5109_c0_g1_i8,DN5109_c0_g1,IRF4_HUMAN,Interferon regulatory factor 4,.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0000790^cellular_component^nuclear chromatin,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:3662`KO:K09445,ENOG411023V^Interferon regulatory factor 4,.,NA,NA,NA,NA,,
yes,JO,interferon,DN5109_c0_g1_i6,DN5109_c0_g1,IRF4_MOUSE,Interferon regulatory factor 4,.,NA,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:mmu:16364`KO:K09445,ENOG411023V^Interferon regulatory factor 4,.,NA,NA,NA,NA,,
yes,JO,interferon,DN5109_c0_g1_i2,DN5109_c0_g1,IRF4_HUMAN,Interferon regulatory factor 4,.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0000790^cellular_component^nuclear chromatin,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:3662`KO:K09445,ENOG411023V^Interferon regulatory factor 4,.,NA,NA,NA,NA,,
yes,JO,interferon,DN5109_c0_g1_i5,DN5109_c0_g1,IRF4_MOUSE,Interferon regulatory factor 4,.,NA,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:mmu:16364`KO:K09445,ENOG411023V^Interferon regulatory factor 4,.,NA,NA,NA,NA,,
yes,JO,interferon,DN5109_c0_g1_i9,DN5109_c0_g1,IRF4_MOUSE,Interferon regulatory factor 4,IRF4_MOUSE,Interferon regulatory factor 4,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:mmu:16364`KO:K09445,ENOG411023V^Interferon regulatory factor 4,PF10401.9^IRF-3^Interferon-regulatory factor 3^1-92^E:1.6e-36,NA,NA,NA,NA,,
yes,JO,interferon,DN4226_c1_g1_i2,DN4226_c1_g1,INLR1_CHICK,Interferon lambda receptor 1,INLR1_CHICK,Interferon lambda receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,.,"ENOG410YYBX^interleukin 28 receptor, alpha (interferon, lambda receptor)",PF01108.17^Tissue_fac^Tissue factor^10-110^E:2e-23,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^123-217^E:1.7e-06",NA,NA,NA,,
yes,JO,interferon,DN4226_c1_g1_i3,DN4226_c1_g1,INLR1_CHICK,Interferon lambda receptor 1,INLR1_CHICK,Interferon lambda receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,.,"ENOG410YYBX^interleukin 28 receptor, alpha (interferon, lambda receptor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN4226_c1_g1_i1,DN4226_c1_g1,INLR1_CHICK,Interferon lambda receptor 1,INLR1_CHICK,Interferon lambda receptor 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,.,"ENOG410YYBX^interleukin 28 receptor, alpha (interferon, lambda receptor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i9,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i2,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i1,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i4,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i10,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i5,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i8,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i6,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i7,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c0_g1_i11,DN14691_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c1_g1_i5,DN14691_c1_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14691_c1_g1_i3,DN14691_c1_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i8,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i9,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i13,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i11,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i2,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN8288_c0_g1_i7,DN8288_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN4523_c0_g1_i4,DN4523_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN4523_c0_g1_i5,DN4523_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN76610_c0_g1_i1,DN76610_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN43033_c0_g1_i2,DN43033_c0_g1,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,.,NA,NA,NA,NA,KEGG:hsa:5612,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN16927_c0_g1_i1,DN16927_c0_g1,IRF5_BOVIN,Interferon regulatory factor 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0019221^biological_process^cytokine-mediated signaling pathway,.,NA,NA,NA,NA,KEGG:bta:615340`KO:K09446,ENOG410XRXT^interferon regulatory factor,.,NA,NA,NA,NA,,
yes,JO,interferon,DN42272_c0_g1_i1,DN42272_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN49474_c0_g1_i1,DN49474_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i7,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i1,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i8,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i5,DN7679_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i3,DN7679_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i12,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i6,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i4,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g1_i2,DN7679_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7679_c0_g2_i1,DN7679_c0_g2,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14377_c0_g1_i1,DN14377_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14377_c0_g1_i2,DN14377_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g1_i4,DN14317_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g1_i2,DN14317_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g1_i3,DN14317_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g1_i1,DN14317_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g2_i1,DN14317_c0_g2,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c0_g2_i2,DN14317_c0_g2,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c1_g1_i2,DN14317_c1_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c1_g1_i3,DN14317_c1_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c1_g1_i1,DN14317_c1_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c2_g1_i1,DN14317_c2_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c2_g2_i3,DN14317_c2_g2,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN14317_c7_g1_i1,DN14317_c7_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN38890_c0_g1_i1,DN38890_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN63340_c0_g1_i1,DN63340_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i13,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i8,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i1,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-141^E:1.1e-45,PF04836.12^IFRD_C^Interferon-related protein conserved region^186-239^E:2.2e-24,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i15,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-211^E:3.7e-76,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i6,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i5,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,IFRD1_PIG,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,KEGG:ssc:493185,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^26-173^E:9e-51,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i14,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i2,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-141^E:4.8e-46,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i10,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i12,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,.,NA,NA,NA,NA,KEGG:ssc:493185,ENOG410XSIZ^Interferon-related developmental regulator,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i4,DN3126_c0_g1,IFRD1_HUMAN,Interferon-related developmental regulator 1,IFRD1_HUMAN,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0007518^biological_process^myoblast fate determination,GO:0030517^biological_process^negative regulation of axon extension,KEGG:hsa:3475,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-91^E:1.1e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN3126_c0_g1_i7,DN3126_c0_g1,IFRD1_PIG,Interferon-related developmental regulator 1,IFRD1_PIG,Interferon-related developmental regulator 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0042692^biological_process^muscle cell differentiation,GO:0030517^biological_process^negative regulation of axon extension,GO:0048671^biological_process^negative regulation of collateral sprouting,KEGG:ssc:493185,ENOG410XSIZ^Interferon-related developmental regulator,PF05004.13^IFRD^Interferon-related developmental regulator (IFRD)^1-139^E:8.7e-48,NA,NA,NA,NA,,
yes,JO,interferon,DN16598_c0_g1_i1,DN16598_c0_g1,IFM5_HUMAN,Interferon-induced transmembrane protein 5,IFM1_HUMAN,Interferon-induced transmembrane protein 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0032991^cellular_component^protein-containing complex,GO:0007166^biological_process^cell surface receptor signaling pathway,KEGG:hsa:8519`KO:K19831,ENOG4112C1U^Interferon induced transmembrane protein,PF04505.12^CD225^Interferon-induced transmembrane protein^90-161^E:1.8e-18,NA,NA,NA,NA,,
yes,JO,interferon,DN33815_c0_g1_i1,DN33815_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN33815_c0_g1_i4,DN33815_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN33815_c0_g1_i6,DN33815_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN33815_c0_g1_i5,DN33815_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN33815_c0_g2_i2,DN33815_c0_g2,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN46791_c0_g1_i1,DN46791_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN46791_c0_g1_i2,DN46791_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN21364_c0_g1_i1,DN21364_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN21364_c0_g2_i1,DN21364_c0_g2,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN37710_c0_g1_i2,DN37710_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN37710_c0_g1_i1,DN37710_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i13,DN3725_c0_g1,GILT_PIG,Gamma-interferon-inducible-lysosomal thiol reductase,.,NA,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,"GO:0016667^molecular_function^oxidoreductase activity, acting on a sulfur group of donors",.,NA,NA,NA,NA,KEGG:ssc:100174943`KO:K08059,ENOG4111IDT^Lysosomal thiol,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i12,DN3725_c0_g1,GILT_PIG,Gamma-interferon-inducible-lysosomal thiol reductase,.,NA,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,"GO:0016667^molecular_function^oxidoreductase activity, acting on a sulfur group of donors",.,NA,NA,NA,NA,KEGG:ssc:100174943`KO:K08059,ENOG4111IDT^Lysosomal thiol,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i8,DN3725_c0_g1,GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,.,.,PF03227.16^GILT^Gamma interferon inducible lysosomal thiol reductase (GILT)^59-185^E:5e-28,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i9,DN3725_c0_g1,GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,.,.,PF03227.16^GILT^Gamma interferon inducible lysosomal thiol reductase (GILT)^59-152^E:8.3e-31,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i1,DN3725_c0_g1,GILT_BOVIN,Gamma-interferon-inducible lysosomal thiol reductase,GILT_BOVIN,Gamma-interferon-inducible lysosomal thiol reductase,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,"GO:0016667^molecular_function^oxidoreductase activity, acting on a sulfur group of donors",GO:0042590^biological_process^antigen processing and presentation of exogenous peptide antigen via MHC class I,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,"GO:0016667^molecular_function^oxidoreductase activity, acting on a sulfur group of donors",GO:0042590^biological_process^antigen processing and presentation of exogenous peptide antigen via MHC class I,NA,KEGG:bta:615930`KO:K08059,ENOG4111IDT^Lysosomal thiol,PF03227.16^GILT^Gamma interferon inducible lysosomal thiol reductase (GILT)^123-215^E:4.6e-18,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i14,DN3725_c0_g1,GILT_DANRE,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:22982335},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0002376^biological_process^immune system process,NA,.,NA,NA,NA,NA,KEGG:dre:336503`KO:K08059,ENOG4111IDT^Lysosomal thiol,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i2,DN3725_c0_g1,GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},.,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3725_c0_g1_i7,DN3725_c0_g1,GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GILT_CARAU,Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000303|PubMed:25447639},GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,GO:0005576^cellular_component^extracellular region,GO:0005764^cellular_component^lysosome,GO:0047134^molecular_function^protein-disulfide reductase activity,GO:0019882^biological_process^antigen processing and presentation,NA,.,.,PF03227.16^GILT^Gamma interferon inducible lysosomal thiol reductase (GILT)^59-161^E:9.3e-32,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i3,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i13,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i11,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i10,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i9,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i4,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i6,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g1_i2,DN10711_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c0_g2_i1,DN10711_c0_g2,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c3_g1_i1,DN10711_c3_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c4_g1_i1,DN10711_c4_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN10711_c5_g1_i1,DN10711_c5_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN52239_c0_g1_i8,DN52239_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i12,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF00605.17^IRF^Interferon regulatory factor transcription factor^14-114^E:7.6e-42,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i1,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,.,NA,NA,NA,NA,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i7,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF00605.17^IRF^Interferon regulatory factor transcription factor^90-142^E:7.8e-17,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i10,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,.,NA,NA,NA,NA,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i6,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF10401.9^IRF-3^Interferon-regulatory factor 3^164-284^E:5.6e-29,PF10401.9^IRF-3^Interferon-regulatory factor 3^330-386^E:2.1e-13,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i13,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF00605.17^IRF^Interferon regulatory factor transcription factor^90-142^E:7.8e-17,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i11,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF00605.17^IRF^Interferon regulatory factor transcription factor^14-114^E:6.1e-41,PF10401.9^IRF-3^Interferon-regulatory factor 3^297-471^E:9.5e-50,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i16,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,.,NA,NA,NA,NA,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i3,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF00605.17^IRF^Interferon regulatory factor transcription factor^90-142^E:2.3e-16,PF10401.9^IRF-3^Interferon-regulatory factor 3^401-575^E:1.4e-49,NA,NA,NA,,
yes,JO,interferon,DN1934_c0_g1_i9,DN1934_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,IRF3_CHICK,Interferon regulatory factor 3,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,PF10401.9^IRF-3^Interferon-regulatory factor 3^204-378^E:6.1e-50,NA,NA,NA,NA,,
yes,JO,interferon,DN25108_c0_g1_i1,DN25108_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN5925_c1_g1_i1,DN5925_c1_g1,INGR1_HUMAN,Interferon gamma receptor 1 {ECO:0000312|HGNC:HGNC:5439},INGR1_HUMAN,Interferon gamma receptor 1 {ECO:0000312|HGNC:HGNC:5439},GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019955^molecular_function^cytokine binding,GO:0004896^molecular_function^cytokine receptor activity,GO:0004906^molecular_function^interferon-gamma receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0019955^molecular_function^cytokine binding,GO:0004896^molecular_function^cytokine receptor activity,GO:0004906^molecular_function^interferon-gamma receptor activity,KEGG:hsa:3459`KO:K05132,ENOG411218K^interferon gamma receptor 1,PF01108.17^Tissue_fac^Tissue factor^46-143^E:3.8e-20,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^157-262^E:3.1e-07",PF07140.11^IFNGR1^Interferon gamma receptor (IFNGR1)^192-336^E:5.1e-08,NA,NA,,
yes,JO,interferon,DN15388_c0_g1_i8,DN15388_c0_g1,IRF4_MOUSE,Interferon regulatory factor 4,IRF4_MOUSE,Interferon regulatory factor 4,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:mmu:16364`KO:K09445,ENOG411023V^Interferon regulatory factor 4,PF00605.17^IRF^Interferon regulatory factor transcription factor^33-138^E:1.5e-42,PF10401.9^IRF-3^Interferon-regulatory factor 3^232-413^E:1e-53,NA,NA,NA,,
yes,JO,interferon,DN15388_c0_g1_i7,DN15388_c0_g1,IRF8_MOUSE,Interferon regulatory factor 8,IRF8_MOUSE,Interferon regulatory factor 8,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:mmu:15900`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,PF00605.17^IRF^Interferon regulatory factor transcription factor^33-138^E:4.6e-43,NA,NA,NA,NA,,
yes,JO,interferon,DN15388_c0_g1_i4,DN15388_c0_g1,IRF4_MOUSE,Interferon regulatory factor 4,.,NA,GO:0000788^cellular_component^nuclear nucleosome,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:mmu:16364`KO:K09445,ENOG411023V^Interferon regulatory factor 4,.,NA,NA,NA,NA,,
yes,JO,interferon,DN23584_c0_g1_i1,DN23584_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN56136_c0_g1_i1,DN56136_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i7,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,IRF8_CHICK,Interferon regulatory factor 8,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,PF00605.17^IRF^Interferon regulatory factor transcription factor^17-121^E:4.3e-42,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i1,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i4,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i8,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i3,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,IRF8_CHICK,Interferon regulatory factor 8,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,PF10401.9^IRF-3^Interferon-regulatory factor 3^4-180^E:4.4e-68,NA,NA,NA,NA,,
yes,JO,interferon,DN3285_c0_g1_i6,DN3285_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,IRF8_CHICK,Interferon regulatory factor 8,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,PF10401.9^IRF-3^Interferon-regulatory factor 3^1-127^E:1e-47,NA,NA,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i6,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_SHEEP,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0019962^molecular_function^type I interferon binding,GO:0004905^molecular_function^type I interferon receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^19-119^E:5.4e-22",PF00041.21^fn3^Fibronectin type III domain^54-103^E:1.2e-05,NA,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i2,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_HUMAN,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^15-122^E:4.9e-19,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^135-231^E:1.8e-20",NA,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i1,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_HUMAN,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^15-122^E:1.1e-18,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^135-231^E:3.9e-20",PF01108.17^Tissue_fac^Tissue factor^227-326^E:1.9e-15,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i8,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_SHEEP,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0019962^molecular_function^type I interferon binding,GO:0004905^molecular_function^type I interferon receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^2-43^E:1.9e-07,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^58-158^E:7.3e-22",PF00041.21^fn3^Fibronectin type III domain^93-142^E:1.5e-05,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i3,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_HUMAN,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^15-122^E:2.8e-18,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^135-231^E:9.2e-20",PF01108.17^Tissue_fac^Tissue factor^227-326^E:4.8e-15,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^341-441^E:2.5e-21",NA,,
yes,JO,interferon,DN3283_c3_g2_i9,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_HUMAN,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^15-122^E:4.9e-19,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^135-231^E:1.8e-20",NA,NA,NA,,
yes,JO,interferon,DN3283_c3_g2_i5,DN3283_c3_g2,INAR1_HUMAN,Interferon alpha/beta receptor 1,INAR1_HUMAN,Interferon alpha/beta receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005770^cellular_component^late endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,KEGG:hsa:3454`KO:K05130,ENOG4111QEU^interferon receptor activity,PF01108.17^Tissue_fac^Tissue factor^15-122^E:4.9e-19,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^135-231^E:1.8e-20",NA,NA,NA,,
yes,JO,interferon,DN19227_c0_g1_i2,DN19227_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN19227_c0_g2_i1,DN19227_c0_g2,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN11158_c0_g1_i1,DN11158_c0_g1,.,NA,IRF9_MOUSE,Interferon regulatory factor 9,.,NA,NA,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0002376^biological_process^immune system process,KEGG:mmu:16391`KO:K04693,ENOG4111AEC^Interferon regulatory factor 9,PF00605.17^IRF^Interferon regulatory factor transcription factor^31-68^E:7e-07,NA,NA,NA,NA,,
yes,JO,interferon,DN11158_c0_g1_i4,DN11158_c0_g1,IRF9_HUMAN,Interferon regulatory factor 9,IRF9_HUMAN,Interferon regulatory factor 9,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:10379`KO:K04693,ENOG4111AEC^Interferon regulatory factor 9,PF00605.17^IRF^Interferon regulatory factor transcription factor^1-50^E:2.5e-08,NA,NA,NA,NA,,
yes,JO,interferon,DN11158_c0_g1_i3,DN11158_c0_g1,IRF9_HUMAN,Interferon regulatory factor 9,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:10379`KO:K04693,ENOG4111AEC^Interferon regulatory factor 9,.,NA,NA,NA,NA,,
yes,JO,interferon,DN11158_c0_g1_i2,DN11158_c0_g1,IRF9_HUMAN,Interferon regulatory factor 9,IRF9_HUMAN,Interferon regulatory factor 9,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:10379`KO:K04693,ENOG4111AEC^Interferon regulatory factor 9,PF00605.17^IRF^Interferon regulatory factor transcription factor^1-50^E:2.5e-08,NA,NA,NA,NA,,
yes,JO,interferon,DN61969_c0_g2_i3,DN61969_c0_g2,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN61969_c0_g2_i5,DN61969_c0_g2,IRF1_CHICK,Interferon regulatory factor 1,IRF1_CHICK,Interferon regulatory factor 1,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN61969_c0_g2_i1,DN61969_c0_g2,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i2,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_BOVIN,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:bta:614253`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^60-109^E:2.9e-15,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i10,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF10401.9^IRF-3^Interferon-regulatory factor 3^123-252^E:8e-45,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i13,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF10401.9^IRF-3^Interferon-regulatory factor 3^48-230^E:5.9e-69,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i12,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^9-114^E:2.2e-39,PF10401.9^IRF-3^Interferon-regulatory factor 3^218-400^E:1.9e-68,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i9,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF10401.9^IRF-3^Interferon-regulatory factor 3^17-199^E:4.2e-69,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i8,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^60-165^E:2.7e-39,PF10401.9^IRF-3^Interferon-regulatory factor 3^269-451^E:2.4e-68,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i11,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF10401.9^IRF-3^Interferon-regulatory factor 3^1-130^E:1e-45,NA,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i1,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^11-116^E:2.2e-39,PF10401.9^IRF-3^Interferon-regulatory factor 3^220-402^E:1.9e-68,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i7,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^10-115^E:1.4e-39,PF10401.9^IRF-3^Interferon-regulatory factor 3^219-348^E:1.7e-44,NA,NA,NA,,
yes,JO,interferon,DN6305_c0_g1_i6,DN6305_c0_g1,IRF6_MOUSE,Interferon regulatory factor 6,IRF6_MOUSE,Interferon regulatory factor 6,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,KEGG:mmu:54139`KO:K10154,ENOG410XRXT^interferon regulatory factor,PF00605.17^IRF^Interferon regulatory factor transcription factor^9-114^E:1.3e-39,PF10401.9^IRF-3^Interferon-regulatory factor 3^218-347^E:1.7e-44,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i3,DN34888_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i2,DN34888_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i9,DN34888_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i8,DN34888_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i4,DN34888_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i7,DN34888_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34888_c0_g1_i6,DN34888_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN34979_c0_g1_i1,DN34979_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN16856_c0_g1_i1,DN16856_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN66617_c0_g2_i1,DN66617_c0_g2,INLR1_CHICK,Interferon lambda receptor 1,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0004896^molecular_function^cytokine receptor activity,GO:0019221^biological_process^cytokine-mediated signaling pathway,GO:0051607^biological_process^defense response to virus,.,NA,NA,NA,NA,.,"ENOG410YYBX^interleukin 28 receptor, alpha (interferon, lambda receptor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN74907_c0_g1_i7,DN74907_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN74907_c0_g1_i4,DN74907_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN74907_c0_g1_i2,DN74907_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN74907_c0_g1_i5,DN74907_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7583_c0_g1_i2,DN7583_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7583_c0_g1_i6,DN7583_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7583_c0_g1_i1,DN7583_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN7583_c0_g1_i3,DN7583_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN169_c0_g1_i1,DN169_c0_g1,I2BP2_MOUSE,Interferon regulatory factor 2-binding protein 2,I2BP2_MOUSE,Interferon regulatory factor 2-binding protein 2,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,KEGG:mmu:270110`KO:K22383,ENOG4110EVD^interferon regulatory factor 2 binding protein 2,PF11261.8^IRF-2BP1_2^Interferon regulatory factor 2-binding protein zinc finger^37-88^E:4.4e-35,NA,NA,NA,NA,,
yes,JO,interferon,DN169_c0_g2_i1,DN169_c0_g2,I2BPL_MOUSE,Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7},I2BPL_MOUSE,Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7},GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,KEGG:mmu:238330`KO:K22383,ENOG410Z1AW^Interferon regulatory factor 2 binding,PF11261.8^IRF-2BP1_2^Interferon regulatory factor 2-binding protein zinc finger^10-61^E:5.7e-35,NA,NA,NA,NA,,
yes,JO,interferon,DN169_c0_g3_i1,DN169_c0_g3,I2BP2_MOUSE,Interferon regulatory factor 2-binding protein 2,I2B2A_DANRE,Interferon regulatory factor 2-binding protein 2-A,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,NA,KEGG:dre:335866`KO:K22383,ENOG4110EVD^interferon regulatory factor 2 binding protein 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN169_c0_g4_i1,DN169_c0_g4,I2BP2_XENTR,Interferon regulatory factor 2-binding protein 2,.,NA,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,NA,.,NA,NA,NA,NA,KEGG:xtr:394851`KO:K22383,ENOG4110EVD^interferon regulatory factor 2 binding protein 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN169_c0_g5_i1,DN169_c0_g5,I2BPL_MOUSE,Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7},I2BPL_MOUSE,Probable E3 ubiquitin-protein ligase IRF2BPL {ECO:0000250|UniProtKB:Q9H1B7},GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,KEGG:mmu:238330`KO:K22383,ENOG410Z1AW^Interferon regulatory factor 2 binding,.,NA,NA,NA,NA,,
yes,JO,interferon,DN133_c0_g2_i4,DN133_c0_g2,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,KEGG:hsa:5612,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",PF05485.12^THAP^THAP domain^46-127^E:1.1e-16,PF14291.6^DUF4371^Domain of unknown function (DUF4371)^200-376^E:2.7e-12,PF05699.14^Dimer_Tnp_hAT^hAT family C-terminal dimerisation region^678-770^E:4.9e-09,NA,NA,,
yes,JO,interferon,DN133_c0_g2_i9,DN133_c0_g2,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,P52K_MOUSE,52 kDa repressor of the inhibitor of the protein kinase,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,NA,KEGG:mmu:72981,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN133_c0_g2_i10,DN133_c0_g2,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,KEGG:hsa:5612,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",PF14291.6^DUF4371^Domain of unknown function (DUF4371)^40-216^E:2.1e-12,PF05699.14^Dimer_Tnp_hAT^hAT family C-terminal dimerisation region^518-610^E:3.6e-09,NA,NA,NA,,
yes,JO,interferon,DN133_c0_g2_i8,DN133_c0_g2,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,P52K_HUMAN,52 kDa repressor of the inhibitor of the protein kinase,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,GO:0000790^cellular_component^nuclear chromatin,GO:0003677^molecular_function^DNA binding,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,KEGG:hsa:5612,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",PF14291.6^DUF4371^Domain of unknown function (DUF4371)^4-159^E:3.5e-11,PF05699.14^Dimer_Tnp_hAT^hAT family C-terminal dimerisation region^461-553^E:3.1e-09,NA,NA,NA,,
yes,JO,interferon,DN37937_c0_g1_i8,DN37937_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN37937_c0_g1_i9,DN37937_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN37937_c0_g1_i4,DN37937_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN37937_c1_g1_i1,DN37937_c1_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN11725_c0_g1_i3,DN11725_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN11725_c0_g1_i2,DN11725_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN11725_c0_g1_i1,DN11725_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN18045_c0_g1_i8,DN18045_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN18045_c0_g1_i2,DN18045_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN18045_c0_g1_i3,DN18045_c0_g1,IRF8_CHICK,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:gga:396385`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i4,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i5,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i3,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i2,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i1,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26297_c0_g1_i9,DN26297_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN26272_c0_g1_i2,DN26272_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN25413_c0_g1_i1,DN25413_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i5,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,IN35_HUMAN,Interferon-induced 35 kDa protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,PF07292.13^NID^Nmi/IFP 35 domain (NID)^143-240^E:2.4e-28,PF07292.13^NID^Nmi/IFP 35 domain (NID)^252-338^E:1.9e-26,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i1,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,.,NA,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i6,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,IN35_HUMAN,Interferon-induced 35 kDa protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,PF07292.13^NID^Nmi/IFP 35 domain (NID)^40-137^E:5.8e-29,NA,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i3,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,IN35_HUMAN,Interferon-induced 35 kDa protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,PF07292.13^NID^Nmi/IFP 35 domain (NID)^59-156^E:1.4e-28,PF07292.13^NID^Nmi/IFP 35 domain (NID)^168-254^E:1.1e-26,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i10,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,IN35_HUMAN,Interferon-induced 35 kDa protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,PF07292.13^NID^Nmi/IFP 35 domain (NID)^215-312^E:3.3e-28,PF07292.13^NID^Nmi/IFP 35 domain (NID)^324-410^E:2.6e-26,NA,NA,NA,,
yes,JO,interferon,DN6170_c0_g1_i11,DN6170_c0_g1,IN35_HUMAN,Interferon-induced 35 kDa protein,IN35_HUMAN,Interferon-induced 35 kDa protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0060337^biological_process^type I interferon signaling pathway,NA,NA,KEGG:hsa:3430,ENOG4111RNW^Interferon-induced protein 35,PF07292.13^NID^Nmi/IFP 35 domain (NID)^161-217^E:5.5e-09,NA,NA,NA,NA,,
yes,JO,interferon,DN39110_c1_g1_i1,DN39110_c1_g1,I2BP2_MOUSE,Interferon regulatory factor 2-binding protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:270110`KO:K22383,ENOG4110EVD^interferon regulatory factor 2 binding protein 2,.,NA,NA,NA,NA,,
yes,JO,interferon,DN40078_c0_g1_i1,DN40078_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1551_c0_g1_i3,DN1551_c0_g1,INGR2_HUMAN,Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440},INGR2_HUMAN,Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440},GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,KEGG:hsa:3460`KO:K05133,ENOG410YR1U^Interferon gamma receptor 2 (Interferon gamma transducer 1),PF01108.17^Tissue_fac^Tissue factor^61-169^E:5.2e-23,"PF09294.10^Interfer-bind^Interferon-alpha/beta receptor, fibronectin type III^181-277^E:8.8e-13",NA,NA,NA,,
yes,JO,interferon,DN1551_c0_g1_i6,DN1551_c0_g1,.,NA,INGR2_HUMAN,Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440},.,NA,NA,NA,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,KEGG:hsa:3460`KO:K05133,ENOG410YR1U^Interferon gamma receptor 2 (Interferon gamma transducer 1),.,NA,NA,NA,NA,,
yes,JO,interferon,DN1551_c0_g1_i7,DN1551_c0_g1,INGR2_HUMAN,Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440},INGR2_HUMAN,Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440},GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0005887^cellular_component^integral component of plasma membrane,KEGG:hsa:3460`KO:K05133,ENOG410YR1U^Interferon gamma receptor 2 (Interferon gamma transducer 1),.,NA,NA,NA,NA,,
yes,JO,interferon,DN55695_c0_g1_i1,DN55695_c0_g1,P52K_MOUSE,52 kDa repressor of the inhibitor of the protein kinase,.,NA,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,NA,.,NA,NA,NA,NA,KEGG:mmu:72981,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN55695_c0_g1_i2,DN55695_c0_g1,P52K_MOUSE,52 kDa repressor of the inhibitor of the protein kinase,.,NA,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0046983^molecular_function^protein dimerization activity,NA,.,NA,NA,NA,NA,KEGG:mmu:72981,"ENOG4110ZMY^protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",.,NA,NA,NA,NA,,
yes,JO,interferon,DN20360_c1_g1_i1,DN20360_c1_g1,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c0_g1_i2,DN22673_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c0_g1_i3,DN22673_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c0_g1_i1,DN22673_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c1_g1_i7,DN22673_c1_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c1_g1_i4,DN22673_c1_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22673_c1_g1_i2,DN22673_c1_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN718_c0_g1_i3,DN718_c0_g1,IFM5_HUMAN,Interferon-induced transmembrane protein 5,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:387733`KO:K06566,ENOG410YP9N^interferon induced transmembrane protein 5,.,NA,NA,NA,NA,,
yes,JO,interferon,DN718_c0_g1_i1,DN718_c0_g1,DSA2B_TORMA,Dispanin subfamily A member 2b,IFM3_HUMAN,Interferon-induced transmembrane protein 3,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0031902^cellular_component^late endosome membrane,GO:0005765^cellular_component^lysosomal membrane,GO:0005886^cellular_component^plasma membrane,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:10410`KO:K06566,ENOG4112C1U^Interferon induced transmembrane protein,PF04505.12^CD225^Interferon-induced transmembrane protein^61-128^E:1.3e-21,NA,NA,NA,NA,,
yes,JO,interferon,DN9824_c0_g1_i1,DN9824_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN28197_c0_g1_i2,DN28197_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN71800_c0_g1_i4,DN71800_c0_g1,.,NA,IFI27_HUMAN,"Interferon alpha-inducible protein 27, mitochondrial {ECO:0000305}",.,NA,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0005739^cellular_component^mitochondrion,KEGG:hsa:3429,ENOG410Z2RX^interferon alpha-inducible protein,PF06140.13^Ifi-6-16^Interferon-induced 6-16 family^29-103^E:1.6e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN71800_c0_g1_i2,DN71800_c0_g1,.,NA,IFI27_HUMAN,"Interferon alpha-inducible protein 27, mitochondrial {ECO:0000305}",.,NA,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0005739^cellular_component^mitochondrion,KEGG:hsa:3429,ENOG410Z2RX^interferon alpha-inducible protein,PF06140.13^Ifi-6-16^Interferon-induced 6-16 family^29-103^E:1.6e-23,NA,NA,NA,NA,,
yes,JO,interferon,DN70005_c0_g1_i2,DN70005_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN52810_c0_g1_i1,DN52810_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN52810_c0_g1_i2,DN52810_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN17443_c0_g1_i8,DN17443_c0_g1,IRF8_HUMAN,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:3394`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN17443_c0_g1_i4,DN17443_c0_g1,IRF8_HUMAN,Interferon regulatory factor 8,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:3394`KO:K10155,ENOG410XNYR^interferon regulatory factor 8,.,NA,NA,NA,NA,,
yes,JO,interferon,DN50155_c0_g1_i1,DN50155_c0_g1,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN50155_c0_g2_i1,DN50155_c0_g2,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN50155_c1_g1_i1,DN50155_c1_g1,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN50155_c3_g1_i1,DN50155_c3_g1,IRF1_CHICK,Interferon regulatory factor 1,IRF1_CHICK,Interferon regulatory factor 1,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN66604_c0_g1_i2,DN66604_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN1634_c0_g1_i7,DN1634_c0_g1,IRF1_CHICK,Interferon regulatory factor 1,IRF1_CHICK,Interferon regulatory factor 1,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",PF00605.17^IRF^Interferon regulatory factor transcription factor^95-199^E:6e-40,NA,NA,NA,NA,,
yes,JO,interferon,DN1634_c0_g1_i9,DN1634_c0_g1,IRF1_CHICK,Interferon regulatory factor 1,IRF1_CHICK,Interferon regulatory factor 1,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",PF00605.17^IRF^Interferon regulatory factor transcription factor^95-199^E:7.8e-40,NA,NA,NA,NA,,
yes,JO,interferon,DN1634_c0_g1_i5,DN1634_c0_g1,IRF1_CHICK,Interferon regulatory factor 1,IRF1_CHICK,Interferon regulatory factor 1,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",PF00605.17^IRF^Interferon regulatory factor transcription factor^95-199^E:2.8e-40,NA,NA,NA,NA,,
yes,JO,interferon,DN1634_c0_g1_i6,DN1634_c0_g1,IRF1_CHICK,Interferon regulatory factor 1,.,NA,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0006915^biological_process^apoptotic process,GO:0002376^biological_process^immune system process,.,NA,NA,NA,NA,KEGG:gga:396384`KO:K09444,"ENOG4111HM7^regulation of CD8-positive, alpha-beta T cell proliferation",.,NA,NA,NA,NA,,
yes,JO,interferon,DN14059_c0_g1_i2,DN14059_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN31392_c0_g1_i9,DN31392_c0_g1,IFRD2_HUMAN,Interferon-related developmental regulator 2,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:7866,ENOG410XSIZ^Interferon-related developmental regulator,.,NA,NA,NA,NA,,
yes,JO,interferon,DN22255_c0_g1_i1,DN22255_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN30579_c0_g1_i1,DN30579_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN110170_c0_g1_i1,DN110170_c0_g1,MX_ANAPL,Interferon-induced GTP-binding protein Mx,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,NA,.,NA,NA,NA,NA,KEGG:apla:101793492`KO:K14754,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN118895_c0_g1_i1,DN118895_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN112672_c0_g1_i1,DN112672_c0_g1,IFRD2_HUMAN,Interferon-related developmental regulator 2,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:7866,ENOG410XSIZ^Interferon-related developmental regulator,.,NA,NA,NA,NA,,
yes,JO,interferon,DN107879_c0_g1_i4,DN107879_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN107879_c0_g1_i1,DN107879_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN107879_c0_g1_i3,DN107879_c0_g1,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN109777_c0_g1_i1,DN109777_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN117645_c0_g1_i1,DN117645_c0_g1,GVIN1_HUMAN,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,JO,interferon,DN117645_c0_g2_i1,DN117645_c0_g2,GVIN1_MOUSE,Interferon-induced very large GTPase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005525^molecular_function^GTP binding,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:100042856,ENOG410Y9GN^Up-regulator of cell proliferation,.,NA,NA,NA,NA,,
yes,JO,interferon,DN113690_c0_g1_i1,DN113690_c0_g1,IRF3_CHICK,Interferon regulatory factor 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0044212^molecular_function^transcription regulatory region DNA binding,GO:0051607^biological_process^defense response to virus,.,NA,NA,NA,NA,KEGG:gga:396330`KO:K09447,ENOG4111G85^interferon regulatory factor 7,.,NA,NA,NA,NA,,
yes,JO,interferon,DN151844_c0_g1_i1,DN151844_c0_g1,IFM5_HUMAN,Interferon-induced transmembrane protein 5,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:387733`KO:K06566,ENOG410YP9N^interferon induced transmembrane protein 5,.,NA,NA,NA,NA,,
yes,JO,interferon,DN151844_c0_g2_i1,DN151844_c0_g2,IFM5_HUMAN,Interferon-induced transmembrane protein 5,IFM5_HUMAN,Interferon-induced transmembrane protein 5,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,KEGG:hsa:387733`KO:K06566,ENOG410YP9N^interferon induced transmembrane protein 5,PF04505.12^CD225^Interferon-induced transmembrane protein^47-114^E:1e-25,NA,NA,NA,NA,,
yes,JO,interferon,DN231641_c0_g1_i1,DN231641_c0_g1,IRF5_HUMAN,Interferon regulatory factor 5,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:hsa:3663`KO:K09446,ENOG410XRXT^interferon regulatory factor,.,NA,NA,NA,NA,,
yes,JO,interferon,DN393489_c0_g1_i1,DN393489_c0_g1,IFM5_HUMAN,Interferon-induced transmembrane protein 5,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0030282^biological_process^bone mineralization,GO:0060349^biological_process^bone morphogenesis,GO:0001701^biological_process^in utero embryonic development,.,NA,NA,NA,NA,KEGG:hsa:387733`KO:K06566,ENOG410YP9N^interferon induced transmembrane protein 5,.,NA,NA,NA,NA,,
no,AD,LEP,DN13938_c0_g2_i1,DN13938_c0_g2,P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i11,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,PF13640.6^2OG-FeII_Oxy_3^2OG-Fe(II) oxygenase superfamily^577-666^E:2.7e-10,PF03171.20^2OG-FeII_Oxy^2OG-Fe(II) oxygenase superfamily^596-667^E:2.6e-08,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i3,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},.,NA,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,.,NA,NA,NA,NA,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i12,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i5,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i8,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN5432_c0_g1_i15,DN5432_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},.,NA,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,.,NA,NA,NA,NA,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
yes,AD,LEP,DN88674_c0_g1_i1,DN88674_c0_g1,OBRG_MELGA,Leptin receptor gene-related protein,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,.,NA,NA,NA,NA,KEGG:mgp:100303675,ENOG4111UCZ^Leptin receptor overlapping,.,NA,NA,NA,NA,,
yes,AD,LEP,DN1476_c1_g1_i4,DN1476_c1_g1,OBRG_MELGA,Leptin receptor gene-related protein,OBRG_MELGA,Leptin receptor gene-related protein,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,KEGG:mgp:100303675,ENOG4111UCZ^Leptin receptor overlapping,PF04133.14^Vps55^Vacuolar protein sorting 55^7-122^E:4.4e-39,NA,NA,NA,NA,,
yes,AD,LEP,DN1476_c1_g1_i1,DN1476_c1_g1,OBRG_MELGA,Leptin receptor gene-related protein,OBRG_MELGA,Leptin receptor gene-related protein,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,GO:0010008^cellular_component^endosome membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,KEGG:mgp:100303675,ENOG4111UCZ^Leptin receptor overlapping,PF04133.14^Vps55^Vacuolar protein sorting 55^7-95^E:4.9e-28,NA,NA,NA,NA,,
no,AD,LEP,DN14166_c0_g1_i8,DN14166_c0_g1,TBA_LEPDS,Tubulin alpha chain,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0005200^molecular_function^structural constituent of cytoskeleton,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,LEP,DN14166_c0_g1_i4,DN14166_c0_g1,TBA_LEPDS,Tubulin alpha chain,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0005200^molecular_function^structural constituent of cytoskeleton,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,LEP,DN14166_c0_g1_i20,DN14166_c0_g1,TBA_LEPDS,Tubulin alpha chain,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005874^cellular_component^microtubule,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0005200^molecular_function^structural constituent of cytoskeleton,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,LEP,DN72266_c1_g1_i1,DN72266_c1_g1,LERL1_PONAB,Leptin receptor overlapping transcript-like 1,.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100171961,ENOG4111UCZ^Leptin receptor overlapping,.,NA,NA,NA,NA,,
no,AD,LEP,DN10921_c0_g1_i3,DN10921_c0_g1,SC65_MOUSE,Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653},SC65_MOUSE,Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0000795^cellular_component^synaptonemal complex,GO:0046849^biological_process^bone remodeling,GO:0032964^biological_process^collagen biosynthetic process,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0000795^cellular_component^synaptonemal complex,GO:0046849^biological_process^bone remodeling,GO:0032964^biological_process^collagen biosynthetic process,KEGG:mmu:66180`KO:K22461,ENOG41118PR^leprecan-like 4,.,NA,NA,NA,NA,,
no,AD,LEP,DN10921_c0_g1_i1,DN10921_c0_g1,SC65_MOUSE,Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653},SC65_HUMAN,Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0000795^cellular_component^synaptonemal complex,GO:0046849^biological_process^bone remodeling,GO:0032964^biological_process^collagen biosynthetic process,GO:1902494^cellular_component^catalytic complex,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005730^cellular_component^nucleolus,GO:0000795^cellular_component^synaptonemal complex,KEGG:hsa:10609`KO:K22461,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN2465_c0_g1_i6,DN2465_c0_g1,ARRD3_HUMAN,Arrestin domain-containing protein 3,LERL1_BOVIN,Leptin receptor overlapping transcript-like 1,GO:0005769^cellular_component^early endosome,GO:0005768^cellular_component^endosome,GO:0005764^cellular_component^lysosome,GO:0005886^cellular_component^plasma membrane,GO:0031699^molecular_function^beta-3 adrenergic receptor binding,GO:0005768^cellular_component^endosome,GO:0016021^cellular_component^integral component of membrane,GO:0032511^biological_process^late endosome to vacuole transport via multivesicular body sorting pathway,GO:2000009^biological_process^negative regulation of protein localization to cell surface,NA,KEGG:bta:513036,ENOG4111UCZ^Leptin receptor overlapping,PF04133.14^Vps55^Vacuolar protein sorting 55^33-149^E:1.7e-39,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i9,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i13,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},.,NA,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,.,NA,NA,NA,NA,KEGG:hsa:10536`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i4,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i3,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:hsa:10536`KO:K22460,ENOG410XPXF^leprecan-like,PF13640.6^2OG-FeII_Oxy_3^2OG-Fe(II) oxygenase superfamily^251-340^E:1.3e-10,PF03171.20^2OG-FeII_Oxy^2OG-Fe(II) oxygenase superfamily^273-341^E:1.3e-06,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i6,DN1565_c0_g1,P3H1_CHICK,Prolyl 3-hydroxylase 1 {ECO:0000250|UniProtKB:Q32P28},P3H2_RAT,Prolyl 3-hydroxylase 2 {ECO:0000312|RGD:1304568},GO:0005783^cellular_component^endoplasmic reticulum,GO:0032991^cellular_component^protein-containing complex,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,KEGG:rno:288016`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i8,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},.,NA,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,.,NA,NA,NA,NA,KEGG:hsa:10536`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN1565_c0_g1_i12,DN1565_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN39371_c0_g1_i1,DN39371_c0_g1,P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,PF13640.6^2OG-FeII_Oxy_3^2OG-Fe(II) oxygenase superfamily^17-56^E:2.6e-06,NA,NA,NA,NA,,
no,AD,LEP,DN39371_c1_g1_i1,DN39371_c1_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},.,NA,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,.,NA,NA,NA,NA,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN22221_c0_g1_i4,DN22221_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},.,NA,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,.,NA,NA,NA,NA,KEGG:hsa:10536`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN22221_c0_g1_i1,DN22221_c0_g1,P3H3_HUMAN,Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318},.,NA,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,.,NA,NA,NA,NA,KEGG:hsa:10536`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
yes,AD,LEP,DN139149_c0_g1_i7,DN139149_c0_g1,LEPR_MACMU,Leptin receptor,.,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0019955^molecular_function^cytokine binding,.,NA,NA,NA,NA,KEGG:mcc:574126`KO:K05062,.,.,NA,NA,NA,NA,,
yes,AD,LEP,DN139149_c0_g1_i6,DN139149_c0_g1,LEPR_PIG,Leptin receptor,LEPR_PIG,Leptin receptor,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0019955^molecular_function^cytokine binding,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0019955^molecular_function^cytokine binding,KEGG:ssc:396836`KO:K05062,ENOG4110JZP^Leptin receptor,PF18589.1^ObR_Ig^Obesity receptor immunoglobulin like domain^1-101^E:1.7e-36,PF06328.11^Lep_receptor_Ig^Ig-like C2-type domain^201-257^E:3.7e-14,NA,NA,NA,,
yes,AD,LEP,DN139149_c0_g1_i1,DN139149_c0_g1,LEPR_RAT,Leptin receptor,LEPR_MACMU,Leptin receptor,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0019955^molecular_function^cytokine binding,KEGG:mcc:574126`KO:K05062,ENOG4110JZP^Leptin receptor,PF18589.1^ObR_Ig^Obesity receptor immunoglobulin like domain^1-101^E:2.1e-36,PF06328.11^Lep_receptor_Ig^Ig-like C2-type domain^201-290^E:3.1e-25,NA,NA,NA,,
yes,AD,LEP,DN139149_c0_g1_i4,DN139149_c0_g1,LEPR_PIG,Leptin receptor,.,NA,GO:0016323^cellular_component^basolateral plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0019955^molecular_function^cytokine binding,.,NA,NA,NA,NA,KEGG:ssc:396836`KO:K05062,ENOG4110JZP^Leptin receptor,.,NA,NA,NA,NA,,
no,AD,LEP,DN153970_c0_g1_i1,DN153970_c0_g1,P3H2_CHICK,Prolyl 3-hydroxylase 2 {ECO:0000250|UniProtKB:Q8IVL5},.,NA,GO:0005604^cellular_component^basement membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016529^cellular_component^sarcoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,.,NA,NA,NA,NA,KEGG:gga:414143`KO:K22459,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LEP,DN200447_c0_g1_i1,DN200447_c0_g1,P3H3_MOUSE,Prolyl 3-hydroxylase 3 {ECO:0000312|MGI:MGI:1315208},.,NA,GO:1902494^cellular_component^catalytic complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005506^molecular_function^iron ion binding,GO:0031418^molecular_function^L-ascorbic acid binding,GO:0019797^molecular_function^procollagen-proline 3-dioxygenase activity,.,NA,NA,NA,NA,KEGG:mmu:14789`KO:K22460,ENOG410XPXF^leprecan-like,.,NA,NA,NA,NA,,
no,AD,LGP2,DN114958_c0_g1_i1,DN114958_c0_g1,DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,.,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",.,NA,NA,NA,NA,,
no,AD,LGP2,DN114958_c0_g1_i2,DN114958_c0_g1,DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,.,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",.,NA,NA,NA,NA,,
no,AD,LGP2,DN144989_c0_g1_i2,DN144989_c0_g1,DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,KEGG:mmu:244310,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",PF03359.13^GKAP^Guanylate-kinase-associated protein (GKAP) protein^1-149^E:7.1e-89,NA,NA,NA,NA,,
no,AD,LGP2,DN144989_c0_g1_i1,DN144989_c0_g1,DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,KEGG:mmu:244310,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",PF03359.13^GKAP^Guanylate-kinase-associated protein (GKAP) protein^1-155^E:2e-85,NA,NA,NA,NA,,
no,AD,LGP2,DN144989_c1_g1_i1,DN144989_c1_g1,DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,.,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",PF03359.13^GKAP^Guanylate-kinase-associated protein (GKAP) protein^514-698^E:2.2e-69,NA,NA,NA,NA,,
no,AD,LGP2,DN147997_c0_g1_i5,DN147997_c0_g1,DLGP2_HUMAN,Disks large-associated protein 2 {ECO:0000305},.,NA,GO:0030054^cellular_component^cell junction,GO:0005883^cellular_component^neurofilament,GO:0005886^cellular_component^plasma membrane,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,.,NA,NA,NA,NA,.,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",.,NA,NA,NA,NA,,
no,AD,LGP2,DN261549_c0_g1_i1,DN261549_c0_g1,DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},DLGP2_MOUSE,Disks large-associated protein 2 {ECO:0000250|UniProtKB:Q9P1A6},GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,GO:0030054^cellular_component^cell junction,GO:0030425^cellular_component^dendrite,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0045211^cellular_component^postsynaptic membrane,KEGG:mmu:244310,"ENOG4111JKV^Discs, large (Drosophila) homolog-associated protein",.,NA,NA,NA,NA,,
no,AD,LIF,DN5608_c0_g1_i2,DN5608_c0_g1,KI67_HUMAN,Proliferation marker protein Ki-67 {ECO:0000305},KI67_MOUSE,Proliferation marker protein Ki-67 {ECO:0000305},GO:0005694^cellular_component^chromosome,GO:0016020^cellular_component^membrane,GO:0016604^cellular_component^nuclear body,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000793^cellular_component^condensed chromosome,GO:0005737^cellular_component^cytoplasm,GO:0016604^cellular_component^nuclear body,GO:0005730^cellular_component^nucleolus,KEGG:mmu:17345`KO:K17582,ENOG410ZXYW^antigen identified by monoclonal antibody Ki-67,PF00498.26^FHA^FHA domain^27-91^E:2.6e-11,PF02178.19^AT_hook^AT hook motif^548-555^E:21,PF15276.6^PP1_bind^Protein phosphatase 1 binding^665-718^E:2.6e-20,PF02178.19^AT_hook^AT hook motif^1394-1400^E:9.6,NA,,
no,AD,LIF,DN54010_c0_g1_i5,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.022",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^549-805^E:6.9e-29,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i8,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.024",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^549-805^E:7.6e-29,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i11,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",.,NA,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,.,NA,NA,NA,NA,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,.,NA,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i12,DN54010_c0_g1,BCAS3_MOUSE,Breast carcinoma-amplified sequence 3 homolog {ECO:0000250|UniProtKB:Q9H6U6},.,NA,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,.,NA,NA,NA,NA,KEGG:mmu:192197,ENOG410XSW7^Breast carcinoma amplified sequence,.,NA,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i9,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.025",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^604-820^E:1.5e-26,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i4,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.026",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^549-805^E:8.8e-29,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i6,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.025",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^549-805^E:8e-29,NA,NA,NA,,
no,AD,LIF,DN54010_c0_g1_i3,DN54010_c0_g1,BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",BCAS3_HUMAN,"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}",GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,KEGG:hsa:54828,ENOG410XSW7^Breast carcinoma amplified sequence,"PF00400.32^WD40^WD domain, G-beta repeat^372-406^E:0.025",PF12490.8^BCAS3^Breast carcinoma amplified sequence 3^549-805^E:8.5e-29,NA,NA,NA,,
no,AD,LIF,DN8767_c0_g1_i6,DN8767_c0_g1,PI16_HUMAN,Peptidase inhibitor 16,CF089_RAT,Bombesin receptor-activated protein C6orf89 homolog,GO:0005615^cellular_component^extracellular space,GO:0030414^molecular_function^peptidase inhibitor activity,GO:0061052^biological_process^negative regulation of cell growth involved in cardiac muscle cell development,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005886^cellular_component^plasma membrane,KEGG:rno:294311,ENOG410YJCN^epithelial cell proliferation,.,NA,NA,NA,NA,,
no,AD,LIF,DN8767_c0_g1_i4,DN8767_c0_g1,CF089_RAT,Bombesin receptor-activated protein C6orf89 homolog,CF089_RAT,Bombesin receptor-activated protein C6orf89 homolog,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005886^cellular_component^plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005886^cellular_component^plasma membrane,KEGG:rno:294311,ENOG410YJCN^epithelial cell proliferation,.,NA,NA,NA,NA,,
no,AD,LIF,DN8767_c0_g1_i3,DN8767_c0_g1,CF089_HUMAN,Bombesin receptor-activated protein C6orf89,CF089_PONAB,Bombesin receptor-activated protein C6orf89 homolog,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005730^cellular_component^nucleolus,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005886^cellular_component^plasma membrane,KEGG:pon:100172815,ENOG410YJCN^epithelial cell proliferation,.,NA,NA,NA,NA,,
no,AD,LIF,DN8767_c0_g1_i5,DN8767_c0_g1,CF089_RAT,Bombesin receptor-activated protein C6orf89 homolog,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030496^cellular_component^midbody,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:rno:294311,ENOG410YJCN^epithelial cell proliferation,.,NA,NA,NA,NA,,
no,AD,LIF,DN6992_c0_g1_i4,DN6992_c0_g1,TNFB_MACEU,Lymphotoxin-alpha,TNFA_CAMBA,Tumor necrosis factor,GO:0005615^cellular_component^extracellular space,GO:0016020^cellular_component^membrane,GO:0005125^molecular_function^cytokine activity,GO:0005164^molecular_function^tumor necrosis factor receptor binding,GO:0050830^biological_process^defense response to Gram-positive bacterium,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005125^molecular_function^cytokine activity,GO:0005164^molecular_function^tumor necrosis factor receptor binding,.,"ENOG410YQC4^Cytokine that binds to TNFRSF1A TNFR1 and TNFRSF1B TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation",PF00229.18^TNF^TNF(Tumour Necrosis Factor) family^99-176^E:1.4e-12,NA,NA,NA,NA,,
no,AD,LIF,DN878_c2_g1_i3,DN878_c2_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,"PF16095.5^COR^C-terminal of Roc, COR, domain^16-244^E:1.1e-13",NA,NA,NA,NA,,
no,AD,LIF,DN5196_c1_g1_i5,DN5196_c1_g1,LFG3_HUMAN,Protein lifeguard 3,LFG3_HUMAN,Protein lifeguard 3,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,PF01027.20^Bax1-I^Inhibitor of apoptosis-promoting Bax1^28-237^E:1.6e-33,NA,NA,NA,NA,,
no,AD,LIF,DN5196_c1_g1_i6,DN5196_c1_g1,LFG3_HUMAN,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN5196_c1_g1_i3,DN5196_c1_g1,LFG3_HUMAN,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN5196_c1_g1_i7,DN5196_c1_g1,LFG3_HUMAN,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN5196_c1_g1_i4,DN5196_c1_g1,LFG3_HUMAN,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN91608_c0_g1_i1,DN91608_c0_g1,.,NA,PPARD_MOUSE,Peroxisome proliferator-activated receptor delta,.,NA,NA,NA,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:mmu:19015`KO:K04504,ENOG410XRZC^receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i1,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^163-247^E:9.6e-41,PF00412.22^LIM^LIM domain^290-350^E:1.6e-12,PF00412.22^LIM^LIM domain^355-411^E:1.8e-13,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i6,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^24-108^E:5.3e-41,PF00412.22^LIM^LIM domain^151-211^E:1.6e-12,PF00412.22^LIM^LIM domain^216-272^E:1.1e-13,PF00412.22^LIM^LIM domain^276-329^E:8.1e-05,NA,,
no,AD,LIF,DN5418_c0_g1_i4,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^159-243^E:9.4e-41,PF00412.22^LIM^LIM domain^286-346^E:1.6e-12,PF00412.22^LIM^LIM domain^351-407^E:1.8e-13,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i5,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^163-247^E:5.8e-41,NA,NA,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i3,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^159-243^E:8.4e-41,PF00412.22^LIM^LIM domain^286-346^E:1.4e-12,PF00412.22^LIM^LIM domain^351-407^E:1.6e-13,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i2,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF00412.22^LIM^LIM domain^12-54^E:4.1e-13,PF00412.22^LIM^LIM domain^59-115^E:3.7e-14,PF00412.22^LIM^LIM domain^119-172^E:2.7e-05,NA,NA,,
no,AD,LIF,DN5418_c0_g1_i8,DN5418_c0_g1,TES_CHICK,Testin,TES_CHICK,Testin,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",PF06297.14^PET^PET Domain^159-243^E:6.6e-41,PF00412.22^LIM^LIM domain^286-346^E:1e-12,NA,NA,NA,,
no,AD,LIF,DN5493_c0_g1_i1,DN5493_c0_g1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,KEGG:hsa:23082`KO:K17963,"ENOG4111HH9^Peroxisome proliferator-activated receptor gamma, coactivator-related 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN5493_c0_g2_i3,DN5493_c0_g2,PPRC1_MOUSE,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:mmu:226169`KO:K17963,"ENOG4111HH9^Peroxisome proliferator-activated receptor gamma, coactivator-related 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN5493_c0_g2_i1,DN5493_c0_g2,PPRC1_MOUSE,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,KEGG:hsa:23082`KO:K17963,"ENOG4111HH9^Peroxisome proliferator-activated receptor gamma, coactivator-related 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN4519_c0_g1_i7,DN4519_c0_g1,LFG4_MOUSE,Protein lifeguard 4,LFG4_MOUSE,Protein lifeguard 4,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0005795^cellular_component^Golgi stack,GO:0016021^cellular_component^integral component of membrane,GO:0006915^biological_process^apoptotic process,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0005795^cellular_component^Golgi stack,GO:0016021^cellular_component^integral component of membrane,GO:0006915^biological_process^apoptotic process,KEGG:mmu:68212`KO:K06890,COG0670^Membrane,PF01027.20^Bax1-I^Inhibitor of apoptosis-promoting Bax1^51-250^E:1.8e-49,NA,NA,NA,NA,,
no,AD,LIF,DN92096_c0_g1_i3,DN92096_c0_g1,PDPFL_HUMAN,Pancreatic progenitor cell differentiation and proliferation factor-like protein,.,NA,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:492307,ENOG41114JA^chromosome 8 open reading frame 22,.,NA,NA,NA,NA,,
no,AD,LIF,DN233_c0_g2_i2,DN233_c0_g2,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,KEGG:mmu:68183`KO:K12861,ENOG41101IB^Breast carcinoma amplified sequence 2,PF05700.11^BCAS2^Breast carcinoma amplified sequence 2 (BCAS2)^20-223^E:1.1e-78,NA,NA,NA,NA,,
no,AD,LIF,DN233_c0_g2_i5,DN233_c0_g2,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,KEGG:mmu:68183`KO:K12861,ENOG41101IB^Breast carcinoma amplified sequence 2,PF05700.11^BCAS2^Breast carcinoma amplified sequence 2 (BCAS2)^20-165^E:8.4e-57,NA,NA,NA,NA,,
no,AD,LIF,DN233_c0_g2_i6,DN233_c0_g2,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,KEGG:mmu:68183`KO:K12861,ENOG41101IB^Breast carcinoma amplified sequence 2,PF05700.11^BCAS2^Breast carcinoma amplified sequence 2 (BCAS2)^20-148^E:2.8e-52,NA,NA,NA,NA,,
no,AD,LIF,DN233_c0_g2_i1,DN233_c0_g2,SPF27_MOUSE,Pre-mRNA-splicing factor SPF27,.,NA,GO:0005813^cellular_component^centrosome,GO:0005662^cellular_component^DNA replication factor A complex,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:68183`KO:K12861,ENOG41101IB^Breast carcinoma amplified sequence 2,.,NA,NA,NA,NA,,
no,AD,LIF,DN233_c0_g2_i3,DN233_c0_g2,SPF27_PONAB,Pre-mRNA-splicing factor SPF27,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0000974^cellular_component^Prp19 complex,GO:0071007^cellular_component^U2-type catalytic step 2 spliceosome,"GO:0000398^biological_process^mRNA splicing, via spliceosome",.,NA,NA,NA,NA,KEGG:pon:100172547`KO:K12861,ENOG41101IB^Breast carcinoma amplified sequence 2,.,NA,NA,NA,NA,,
no,AD,LIF,DN31514_c0_g1_i2,DN31514_c0_g1,PA2G4_RAT,Proliferation-associated protein 2G4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0003676^molecular_function^nucleic acid binding,GO:0003723^molecular_function^RNA binding,GO:0043066^biological_process^negative regulation of apoptotic process,.,NA,NA,NA,NA,KEGG:rno:288778,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i3,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^618-800^E:1e-66,PF00595.24^PDZ^PDZ domain^946-1015^E:4.8e-05,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1424-1646^E:6.8e-71,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i1,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^2-141^E:2.9e-45,NA,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i8,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^618-800^E:3.7e-67,NA,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i9,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF00595.24^PDZ^PDZ domain^96-166^E:2e-05,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^571-677^E:1.4e-28,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^689-749^E:6e-07,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i5,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^179-401^E:5.9e-72,NA,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i10,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^15-77^E:1.5e-08,NA,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i6,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^618-800^E:9.9e-67,PF00595.24^PDZ^PDZ domain^946-1015^E:4.6e-05,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1420-1526^E:3.1e-28,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1538-1598^E:1.3e-06,NA,,
no,AD,LIF,DN21754_c0_g1_i2,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^618-800^E:1e-66,PF00595.24^PDZ^PDZ domain^946-1015^E:4.7e-05,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1420-1642^E:6.6e-71,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i7,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF00595.24^PDZ^PDZ domain^96-166^E:2e-06,PF17820.1^PDZ_6^PDZ domain^115-165^E:1.7e-06,NA,NA,NA,,
no,AD,LIF,DN21754_c0_g1_i11,DN21754_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^618-800^E:9.9e-67,PF00595.24^PDZ^PDZ domain^946-1015^E:4.6e-05,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1420-1642^E:6.4e-71,NA,NA,,
yes ,AD,LIF,DN12675_c0_g1_i1,DN12675_c0_g1,LIFR_CANLF,Leukemia inhibitory factor receptor,LIFR_CANLF,Leukemia inhibitory factor receptor,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,KEGG:cfa:449478`KO:K05058,ENOG410ZMDF^Leukemia inhibitory factor receptor alpha,PF17971.1^LIFR_D2^Leukemia inhibitory factor receptor D2 domain^117-228^E:8.2e-52,NA,NA,NA,NA,,
yes ,AD,LIF,DN12675_c0_g1_i2,DN12675_c0_g1,LIFR_CANLF,Leukemia inhibitory factor receptor,LIFR_HUMAN,Leukemia inhibitory factor receptor,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:3977`KO:K05058,ENOG410ZMDF^Leukemia inhibitory factor receptor alpha,.,NA,NA,NA,NA,,
yes ,AD,LIF,DN12675_c0_g1_i3,DN12675_c0_g1,LIFR_CANLF,Leukemia inhibitory factor receptor,LIFR_CANLF,Leukemia inhibitory factor receptor,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,KEGG:cfa:449478`KO:K05058,ENOG410ZMDF^Leukemia inhibitory factor receptor alpha,PF17971.1^LIFR_D2^Leukemia inhibitory factor receptor D2 domain^117-228^E:8.2e-52,NA,NA,NA,NA,,
no,AD,LIF,DN620_c0_g1_i8,DN620_c0_g1,PCNA_MACFA,Proliferating cell nuclear antigen,.,NA,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0016604^cellular_component^nuclear body,GO:0043596^cellular_component^nuclear replication fork,GO:0043626^cellular_component^PCNA complex,.,NA,NA,NA,NA,KEGG:mcf:102124021`KO:K04802,.,.,NA,NA,NA,NA,,
no,AD,LIF,DN620_c0_g1_i9,DN620_c0_g1,PCNA_CHICK,Proliferating cell nuclear antigen,PCNA_CHICK,Proliferating cell nuclear antigen,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,KEGG:gga:373984`KO:K04802,COG0592^DNA polymerase processivity factor activity,"PF02747.15^PCNA_C^Proliferating cell nuclear antigen, C-terminal domain^1-116^E:5.5e-57",NA,NA,NA,NA,,
no,AD,LIF,DN620_c0_g1_i10,DN620_c0_g1,PCNA_CHICK,Proliferating cell nuclear antigen,PCNA_COTJA,Proliferating cell nuclear antigen,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,GO:0070557^cellular_component^PCNA-p21 complex,GO:0003677^molecular_function^DNA binding,GO:0030337^molecular_function^DNA polymerase processivity factor activity,GO:0006260^biological_process^DNA replication,GO:0006275^biological_process^regulation of DNA replication,KEGG:cjo:107323623`KO:K04802,COG0592^DNA polymerase processivity factor activity,"PF00705.18^PCNA_N^Proliferating cell nuclear antigen, N-terminal domain^34-106^E:2.4e-34",NA,NA,NA,NA,,
no,AD,LIF,DN620_c0_g1_i1,DN620_c0_g1,PCNA_CHICK,Proliferating cell nuclear antigen,.,NA,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,.,NA,NA,NA,NA,KEGG:gga:373984`KO:K04802,COG0592^DNA polymerase processivity factor activity,.,NA,NA,NA,NA,,
no,AD,LIF,DN620_c0_g1_i4,DN620_c0_g1,PCNA_CHICK,Proliferating cell nuclear antigen,PCNA_CHICK,Proliferating cell nuclear antigen,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,KEGG:gga:373984`KO:K04802,COG0592^DNA polymerase processivity factor activity,"PF00705.18^PCNA_N^Proliferating cell nuclear antigen, N-terminal domain^34-157^E:3.2e-58",PF02144.16^Rad1^Repair protein Rad1/Rec1/Rad17^35-263^E:6.8e-06,PF04139.13^Rad9^Rad9^47-246^E:1.5e-06,"PF02747.15^PCNA_C^Proliferating cell nuclear antigen, C-terminal domain^160-287^E:1.8e-63",NA,,
no,AD,LIF,DN620_c0_g1_i2,DN620_c0_g1,PCNA_CHICK,Proliferating cell nuclear antigen,PCNA_CHICK,Proliferating cell nuclear antigen,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,GO:0005813^cellular_component^centrosome,GO:0000785^cellular_component^chromatin,GO:0000307^cellular_component^cyclin-dependent protein kinase holoenzyme complex,GO:0016604^cellular_component^nuclear body,GO:0005652^cellular_component^nuclear lamina,KEGG:gga:373984`KO:K04802,COG0592^DNA polymerase processivity factor activity,"PF00705.18^PCNA_N^Proliferating cell nuclear antigen, N-terminal domain^34-157^E:1.7e-58","PF02747.15^PCNA_C^Proliferating cell nuclear antigen, C-terminal domain^160-228^E:3.3e-30",NA,NA,NA,,
no,AD,LIF,DN52770_c0_g1_i3,DN52770_c0_g1,PA2G4_MOUSE,Proliferation-associated protein 2G4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:mmu:18813,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN5274_c0_g1_i1,DN5274_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN5274_c0_g1_i2,DN5274_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN5274_c0_g1_i4,DN5274_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,SIPA1_MOUSE,Signal-induced proliferation-associated protein 1,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0030133^cellular_component^transport vesicle,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN5274_c0_g1_i6,DN5274_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN5274_c0_g1_i3,DN5274_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN3420_c0_g4_i1,DN3420_c0_g4,PPARD_HUMAN,Peroxisome proliferator-activated receptor delta,PPARD_HUMAN,Peroxisome proliferator-activated receptor delta,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,KEGG:hsa:5467`KO:K04504,ENOG410XRZC^receptor,"PF00105.18^zf-C4^Zinc finger, C4 type (two domains)^74-140^E:4.4e-28",PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^247-417^E:4.4e-16,NA,NA,NA,,
no,AD,LIF,DN29483_c0_g1_i1,DN29483_c0_g1,PPARD_HUMAN,Peroxisome proliferator-activated receptor delta,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:hsa:5467`KO:K04504,ENOG410XRZC^receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN7499_c3_g1_i1,DN7499_c3_g1,.,NA,MFHA1_MOUSE,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},.,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0031625^molecular_function^ubiquitin protein ligase binding,GO:0006952^biological_process^defense response,KEGG:mmu:52065,COG4886^leucine Rich Repeat,PF13855.6^LRR_8^Leucine rich repeat^78-137^E:4.2e-12,PF00560.33^LRR_1^Leucine Rich Repeat^79-89^E:1100,PF13516.6^LRR_6^Leucine Rich repeat^79-86^E:1600,PF13516.6^LRR_6^Leucine Rich repeat^102-113^E:140,PF00560.33^LRR_1^Leucine Rich Repeat^103-124^E:0.74,,
no,AD,LIF,DN11470_c0_g1_i2,DN11470_c0_g1,PRGC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PRGC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,GO:0097440^cellular_component^apical dendrite,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043025^cellular_component^neuronal cell body,GO:0097440^cellular_component^apical dendrite,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043025^cellular_component^neuronal cell body,KEGG:hsa:10891`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha","PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^698-758^E:7.8e-07",NA,NA,NA,NA,,
no,AD,LIF,DN11470_c0_g1_i8,DN11470_c0_g1,PRGC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,.,NA,GO:0097440^cellular_component^apical dendrite,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043025^cellular_component^neuronal cell body,.,NA,NA,NA,NA,KEGG:hsa:10891`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha",.,NA,NA,NA,NA,,
no,AD,LIF,DN11470_c0_g1_i5,DN11470_c0_g1,PRGC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PRGC1_PIG,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,GO:0097440^cellular_component^apical dendrite,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043025^cellular_component^neuronal cell body,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0031490^molecular_function^chromatin DNA binding,GO:0003677^molecular_function^DNA binding,GO:0016922^molecular_function^nuclear receptor binding,KEGG:ssc:397013`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha","PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^181-241^E:1.9e-07",NA,NA,NA,NA,,
no,AD,LIF,DN11470_c0_g1_i7,DN11470_c0_g1,PRGC1_PIG,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,.,NA,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0031490^molecular_function^chromatin DNA binding,GO:0003677^molecular_function^DNA binding,GO:0016922^molecular_function^nuclear receptor binding,.,NA,NA,NA,NA,KEGG:ssc:397013`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha",.,NA,NA,NA,NA,,
no,AD,LIF,DN11470_c0_g1_i6,DN11470_c0_g1,PRGC1_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PRGC1_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,GO:0097440^cellular_component^apical dendrite,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0097440^cellular_component^apical dendrite,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,KEGG:rno:83516`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha",.,NA,NA,NA,NA,,
no,AD,LIF,DN11470_c0_g1_i1,DN11470_c0_g1,PRGC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,PRGC1_BOVIN,Peroxisome proliferator-activated receptor gamma coactivator 1-alpha,GO:0097440^cellular_component^apical dendrite,GO:0022626^cellular_component^cytosolic ribosome,GO:1990844^cellular_component^interfibrillar mitochondrion,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0043025^cellular_component^neuronal cell body,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0031490^molecular_function^chromatin DNA binding,GO:0003677^molecular_function^DNA binding,GO:0016922^molecular_function^nuclear receptor binding,KEGG:bta:338446`KO:K07202,"ENOG410YQI0^peroxisome proliferator-activated receptor gamma, coactivator 1 alpha",.,NA,NA,NA,NA,,
no,AD,LIF,DN11576_c1_g1_i1,DN11576_c1_g1,MFHA1_HUMAN,Malignant fibrous histiocytoma-amplified sequence 1 {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0051721^molecular_function^protein phosphatase 2A binding,GO:0031625^molecular_function^ubiquitin protein ligase binding,GO:0030218^biological_process^erythrocyte differentiation,.,NA,NA,NA,NA,KEGG:hsa:9258,COG4886^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,LIF,DN10673_c0_g1_i3,DN10673_c0_g1,LIF_BOVIN,Leukemia inhibitory factor,LIF_BOVIN,Leukemia inhibitory factor,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,KEGG:bta:280840`KO:K05419,ENOG410YVPP^Leukemia inhibitory factor,PF01291.17^LIF_OSM^LIF / OSM family^55-213^E:2.5e-32,NA,NA,NA,NA,,
yes,AD,LIF,DN10673_c0_g1_i2,DN10673_c0_g1,LIF_BOVIN,Leukemia inhibitory factor,LIF_BOVIN,Leukemia inhibitory factor,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,KEGG:bta:280840`KO:K05419,ENOG410YVPP^Leukemia inhibitory factor,PF01291.17^LIF_OSM^LIF / OSM family^46-204^E:2.2e-32,NA,NA,NA,NA,,
yes,AD,LIF,DN10673_c0_g1_i1,DN10673_c0_g1,LIF_BOVIN,Leukemia inhibitory factor,LIF_BOVIN,Leukemia inhibitory factor,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0005146^molecular_function^leukemia inhibitory factor receptor binding,GO:0006955^biological_process^immune response,KEGG:bta:280840`KO:K05419,ENOG410YVPP^Leukemia inhibitory factor,PF01291.17^LIF_OSM^LIF / OSM family^80-238^E:3.5e-32,NA,NA,NA,NA,,
no,AD,LIF,DN7716_c0_g1_i4,DN7716_c0_g1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,KEGG:hsa:56654,"ENOG4111QDP^neural proliferation, differentiation and control, 1",PF06809.11^NPDC1^Neural proliferation differentiation control-1 protein (NPDC1)^96-285^E:3.3e-65,NA,NA,NA,NA,,
no,AD,LIF,DN7716_c0_g1_i2,DN7716_c0_g1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,KEGG:hsa:56654,"ENOG4111QDP^neural proliferation, differentiation and control, 1",PF06809.11^NPDC1^Neural proliferation differentiation control-1 protein (NPDC1)^38-173^E:5.2e-32,NA,NA,NA,NA,,
no,AD,LIF,DN7716_c0_g1_i1,DN7716_c0_g1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,KEGG:hsa:56654,"ENOG4111QDP^neural proliferation, differentiation and control, 1",PF06809.11^NPDC1^Neural proliferation differentiation control-1 protein (NPDC1)^11-325^E:8.8e-80,NA,NA,NA,NA,,
no,AD,LIF,DN7716_c0_g1_i6,DN7716_c0_g1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,NPDC1_HUMAN,Neural proliferation differentiation and control protein 1,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0050776^biological_process^regulation of immune response,NA,NA,KEGG:hsa:56654,"ENOG4111QDP^neural proliferation, differentiation and control, 1",PF06809.11^NPDC1^Neural proliferation differentiation control-1 protein (NPDC1)^11-304^E:7.5e-68,NA,NA,NA,NA,,
no,AD,LIF,DN7716_c0_g2_i1,DN7716_c0_g2,NPDC1_MOUSE,Neural proliferation differentiation and control protein 1,.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:18146,"ENOG4111QDP^neural proliferation, differentiation and control, 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN41687_c0_g1_i1,DN41687_c0_g1,LFG2_HUMAN,Protein lifeguard 2,LFG2_HUMAN,Protein lifeguard 2,GO:0030054^cellular_component^cell junction,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,GO:0030054^cellular_component^cell junction,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,KEGG:hsa:23017,COG0670^Membrane,PF01027.20^Bax1-I^Inhibitor of apoptosis-promoting Bax1^96-306^E:1.2e-31,NA,NA,NA,NA,,
no,AD,LIF,DN5986_c0_g1_i3,DN5986_c0_g1,F120B_BOVIN,Constitutive coactivator of peroxisome proliferator-activated receptor gamma,F120B_BOVIN,Constitutive coactivator of peroxisome proliferator-activated receptor gamma,GO:0005634^cellular_component^nucleus,GO:0045444^biological_process^fat cell differentiation,GO:0035357^biological_process^peroxisome proliferator activated receptor signaling pathway,NA,NA,GO:0005634^cellular_component^nucleus,GO:0045444^biological_process^fat cell differentiation,GO:0035357^biological_process^peroxisome proliferator activated receptor signaling pathway,NA,NA,KEGG:bta:524306,ENOG410ZBE9^family with sequence similarity 120B,PF12813.7^XPG_I_2^XPG domain containing^194-280^E:1.8e-06,NA,NA,NA,NA,,
no,AD,LIF,DN5986_c0_g1_i5,DN5986_c0_g1,F120B_BOVIN,Constitutive coactivator of peroxisome proliferator-activated receptor gamma,F120B_BOVIN,Constitutive coactivator of peroxisome proliferator-activated receptor gamma,GO:0005634^cellular_component^nucleus,GO:0045444^biological_process^fat cell differentiation,GO:0035357^biological_process^peroxisome proliferator activated receptor signaling pathway,NA,NA,GO:0005634^cellular_component^nucleus,GO:0045444^biological_process^fat cell differentiation,GO:0035357^biological_process^peroxisome proliferator activated receptor signaling pathway,NA,NA,KEGG:bta:524306,ENOG410ZBE9^family with sequence similarity 120B,PF12813.7^XPG_I_2^XPG domain containing^145-229^E:5.2e-07,NA,NA,NA,NA,,
no,AD,LIF,DN14532_c0_g1_i1,DN14532_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,KEGG:hsa:23094`KO:K17703,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^70-265^E:8.2e-50,NA,NA,NA,NA,,
no,AD,LIF,DN14532_c0_g1_i3,DN14532_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,KEGG:hsa:23094`KO:K17703,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^9-153^E:1.2e-29,NA,NA,NA,NA,,
no,AD,LIF,DN22803_c0_g1_i4,DN22803_c0_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,PF13516.6^LRR_6^Leucine Rich repeat^48-63^E:2.6,PF00560.33^LRR_1^Leucine Rich Repeat^52-62^E:130,PF13516.6^LRR_6^Leucine Rich repeat^71-84^E:83,PF00560.33^LRR_1^Leucine Rich Repeat^73-89^E:330,PF13516.6^LRR_6^Leucine Rich repeat^96-107^E:630,,
no,AD,LIF,DN22803_c0_g1_i2,DN22803_c0_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,PF00025.21^Arf^ADP-ribosylation factor family^36-120^E:1e-07,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^43-159^E:1e-16",PF00071.22^Ras^Ras family^43-175^E:6.4e-07,PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^45-133^E:8.4e-05,"PF16095.5^COR^C-terminal of Roc, COR, domain^304-521^E:1.1e-09",,
no,AD,LIF,DN63549_c0_g1_i8,DN63549_c0_g1,LFG1_MOUSE,Protein lifeguard 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0044325^molecular_function^ion channel binding,GO:0032469^biological_process^endoplasmic reticulum calcium ion homeostasis,.,NA,NA,NA,NA,KEGG:mmu:66168`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN8146_c0_g1_i30,DN8146_c0_g1,MTCP1_MOUSE,Protein p13 MTCP-1,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0032991^cellular_component^protein-containing complex,GO:0019901^molecular_function^protein kinase binding,GO:0043539^molecular_function^protein serine/threonine kinase activator activity,GO:0033138^biological_process^positive regulation of peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:mmu:17763`KO:K16837,ENOG41116AR^Mature T-cell proliferation 1,.,NA,NA,NA,NA,,
no,AD,LIF,DN8146_c0_g1_i22,DN8146_c0_g1,MTCP1_MOUSE,Protein p13 MTCP-1,.,NA,GO:0005739^cellular_component^mitochondrion,GO:0032991^cellular_component^protein-containing complex,GO:0019901^molecular_function^protein kinase binding,GO:0043539^molecular_function^protein serine/threonine kinase activator activity,GO:0033138^biological_process^positive regulation of peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:mmu:17763`KO:K16837,ENOG41116AR^Mature T-cell proliferation 1,.,NA,NA,NA,NA,,
no,AD,LIF,DN20182_c0_g1_i1,DN20182_c0_g1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,.,NA,NA,NA,NA,KEGG:hsa:23082`KO:K17963,"ENOG4111HH9^Peroxisome proliferator-activated receptor gamma, coactivator-related 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN20182_c0_g1_i2,DN20182_c0_g1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,PPRC1_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator-related protein 1,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030374^molecular_function^nuclear receptor transcription coactivator activity,GO:0003723^molecular_function^RNA binding,GO:0003712^molecular_function^transcription coregulator activity,KEGG:hsa:23082`KO:K17963,"ENOG4111HH9^Peroxisome proliferator-activated receptor gamma, coactivator-related 1",.,NA,NA,NA,NA,,
no,AD,LIF,DN27481_c0_g1_i2,DN27481_c0_g1,HEMGN_MOUSE,Hemogen,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,GO:0045667^biological_process^regulation of osteoblast differentiation,NA,.,NA,NA,NA,NA,KEGG:mmu:93966,ENOG411096P^Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB),.,NA,NA,NA,NA,,
no,AD,LIF,DN11153_c0_g1_i1,DN11153_c0_g1,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,KEGG:ssc:397671`KO:K08530,ENOG410XRZC^receptor,PF12577.8^PPARgamma_N^PPAR gamma N-terminal region^1-78^E:1.6e-34,"PF00105.18^zf-C4^Zinc finger, C4 type (two domains)^108-174^E:2.9e-27",PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^290-455^E:1.4e-16,NA,NA,,
no,AD,LIF,DN11153_c0_g1_i3,DN11153_c0_g1,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,KEGG:ssc:397671`KO:K08530,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^41-206^E:1.9e-17,NA,NA,NA,NA,,
no,AD,LIF,DN11153_c0_g1_i2,DN11153_c0_g1,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,PPARG_PIG,Peroxisome proliferator-activated receptor gamma,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0033613^molecular_function^activating transcription factor binding,GO:0051393^molecular_function^alpha-actinin binding,KEGG:ssc:397671`KO:K08530,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^129-294^E:5.7e-17,NA,NA,NA,NA,,
no,AD,LIF,DN95361_c0_g1_i1,DN95361_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,.,NA,NA,NA,NA,KEGG:hsa:23094`KO:K17703,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN6394_c1_g1_i1,DN6394_c1_g1,PRGC2_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,.,NA,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,.,NA,NA,NA,NA,KEGG:hsa:133522`KO:K17962,"ENOG4111PZ5^Peroxisome proliferator-activated receptor gamma, coactivator 1 beta",.,NA,NA,NA,NA,,
no,AD,LIF,DN6394_c1_g1_i5,DN6394_c1_g1,PRGC2_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,KEGG:rno:291567`KO:K17962,"ENOG4111PZ5^Peroxisome proliferator-activated receptor gamma, coactivator 1 beta",.,NA,NA,NA,NA,,
no,AD,LIF,DN6394_c1_g1_i3,DN6394_c1_g1,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,KEGG:rno:291567`KO:K17962,"ENOG4111PZ5^Peroxisome proliferator-activated receptor gamma, coactivator 1 beta",.,NA,NA,NA,NA,,
no,AD,LIF,DN6394_c1_g1_i4,DN6394_c1_g1,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,KEGG:rno:291567`KO:K17962,"ENOG4111PZ5^Peroxisome proliferator-activated receptor gamma, coactivator 1 beta",.,NA,NA,NA,NA,,
no,AD,LIF,DN6394_c1_g1_i2,DN6394_c1_g1,PRGC2_RAT,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,PRGC2_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-beta,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,GO:0030331^molecular_function^estrogen receptor binding,GO:0016592^cellular_component^mediator complex,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0050682^molecular_function^AF-2 domain binding,KEGG:hsa:133522`KO:K17962,"ENOG4111PZ5^Peroxisome proliferator-activated receptor gamma, coactivator 1 beta","PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^918-981^E:1.1e-10",NA,NA,NA,NA,,
no,AD,LIF,DN10365_c1_g1_i1,DN10365_c1_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,.,NA,NA,NA,NA,,
no,AD,LIF,DN34976_c0_g1_i2,DN34976_c0_g1,NBAS_HUMAN,Neuroblastoma-amplified sequence,.,NA,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:51594`KO:K20473,ENOG410YJNG^Neuroblastoma amplified sequence,.,NA,NA,NA,NA,,
no,AD,LIF,DN34976_c0_g3_i1,DN34976_c0_g3,NBAS_HUMAN,Neuroblastoma-amplified sequence,NBAS_HUMAN,Neuroblastoma-amplified sequence,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,KEGG:hsa:51594`KO:K20473,ENOG410YJNG^Neuroblastoma amplified sequence,"PF15492.6^Nbas_N^Neuroblastoma-amplified sequence, N terminal^108-388^E:2.3e-172",PF08314.11^Sec39^Secretory pathway protein Sec39^741-1377^E:6.4e-29,NA,NA,NA,,
no,AD,LIF,DN34976_c0_g3_i3,DN34976_c0_g3,NBAS_HUMAN,Neuroblastoma-amplified sequence,NBAS_HUMAN,Neuroblastoma-amplified sequence,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,KEGG:hsa:51594`KO:K20473,ENOG410YJNG^Neuroblastoma amplified sequence,"PF15492.6^Nbas_N^Neuroblastoma-amplified sequence, N terminal^108-388^E:2.4e-172",PF08314.11^Sec39^Secretory pathway protein Sec39^741-1377^E:6.9e-29,NA,NA,NA,,
no,AD,LIF,DN34976_c0_g3_i2,DN34976_c0_g3,NBAS_HUMAN,Neuroblastoma-amplified sequence,NBAS_HUMAN,Neuroblastoma-amplified sequence,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0005829^cellular_component^cytosol,GO:0070939^cellular_component^Dsl1/NZR complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,KEGG:hsa:51594`KO:K20473,ENOG410YJNG^Neuroblastoma amplified sequence,"PF15492.6^Nbas_N^Neuroblastoma-amplified sequence, N terminal^108-388^E:2.3e-172",PF08314.11^Sec39^Secretory pathway protein Sec39^741-1377^E:6.3e-29,NA,NA,NA,,
no,AD,LIF,DN51052_c0_g1_i1,DN51052_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN3587_c0_g1_i6,DN3587_c0_g1,SI1L3_MOUSE,Signal-induced proliferation-associated 1-like protein 3,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0005096^molecular_function^GTPase activator activity,.,NA,NA,NA,NA,KEGG:mmu:74206`KO:K17703,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN3587_c0_g1_i1,DN3587_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,KEGG:hsa:23094`KO:K17703,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN3587_c0_g1_i8,DN3587_c0_g1,SIPA1_HUMAN,Signal-induced proliferation-associated protein 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0032991^cellular_component^protein-containing complex,.,NA,NA,NA,NA,KEGG:hsa:6494`KO:K08013,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN3587_c0_g1_i7,DN3587_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,.,NA,NA,NA,NA,KEGG:hsa:23094`KO:K17703,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN3587_c0_g1_i2,DN3587_c0_g1,SI1L3_HUMAN,Signal-induced proliferation-associated 1-like protein 3,SI1L3_MOUSE,Signal-induced proliferation-associated 1-like protein 3,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0045177^cellular_component^apical part of cell,GO:0016324^cellular_component^apical plasma membrane,GO:0001725^cellular_component^stress fiber,GO:0061689^cellular_component^tricellular tight junction,GO:0005096^molecular_function^GTPase activator activity,KEGG:mmu:74206`KO:K17703,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^567-749^E:1.7e-68,NA,NA,NA,NA,,
no,AD,LIF,DN58466_c0_g1_i1,DN58466_c0_g1,MCTS1_RAT,Malignant T-cell-amplified sequence 1,.,NA,GO:0022627^cellular_component^cytosolic small ribosomal subunit,GO:0005886^cellular_component^plasma membrane,GO:0003723^molecular_function^RNA binding,GO:0007049^biological_process^cell cycle,GO:0006974^biological_process^cellular response to DNA damage stimulus,.,NA,NA,NA,NA,KEGG:rno:302500`KO:K07575,COG2016^Rna-binding protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN7551_c0_g2_i6,DN7551_c0_g2,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,KEGG:hsa:26037`KO:K17701,ENOG410XTIX^gtpase activating protein,PF02145.15^Rap_GAP^Rap/ran-GAP^628-810^E:1.4e-68,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1487-1730^E:4.3e-85,NA,NA,NA,,
no,AD,LIF,DN7551_c0_g2_i1,DN7551_c0_g2,SI1L1_MOUSE,Signal-induced proliferation-associated 1-like protein 1,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0098978^cellular_component^glutamatergic synapse,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,KEGG:hsa:26037`KO:K17701,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^1-236^E:2.9e-87,NA,NA,NA,NA,,
no,AD,LIF,DN7551_c0_g2_i5,DN7551_c0_g2,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,KEGG:hsa:26037`KO:K17701,ENOG410XTIX^gtpase activating protein,PF11881.8^SPAR_C^C-terminal domain of SPAR protein^2-235^E:1.6e-83,NA,NA,NA,NA,,
no,AD,LIF,DN46996_c0_g1_i1,DN46996_c0_g1,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:cfa:403654`KO:K07294,ENOG410XRZC^receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i5,DN4885_c0_g1,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,KEGG:hsa:5465`KO:K07294,ENOG410XRZC^receptor,"PF00105.18^zf-C4^Zinc finger, C4 type (two domains)^101-167^E:2.5e-28",PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^276-448^E:1.2e-15,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i3,DN4885_c0_g1,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:cfa:403654`KO:K07294,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^32-205^E:1.5e-16,NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i8,DN4885_c0_g1,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:cfa:403654`KO:K07294,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^32-205^E:1.5e-16,NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i2,DN4885_c0_g1,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,KEGG:hsa:5465`KO:K07294,ENOG410XRZC^receptor,"PF00105.18^zf-C4^Zinc finger, C4 type (two domains)^101-124^E:3.9e-09",NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i4,DN4885_c0_g1,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:cfa:403654`KO:K07294,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^32-205^E:1.5e-16,NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i6,DN4885_c0_g1,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:cfa:403654`KO:K07294,ENOG410XRZC^receptor,PF00104.30^Hormone_recep^Ligand-binding domain of nuclear hormone receptor^72-245^E:2.5e-16,NA,NA,NA,NA,,
no,AD,LIF,DN4885_c0_g1_i7,DN4885_c0_g1,PPARA_CANLF,Peroxisome proliferator-activated receptor alpha,PPARA_HUMAN,Peroxisome proliferator-activated receptor alpha,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,KEGG:hsa:5465`KO:K07294,ENOG410XRZC^receptor,"PF00105.18^zf-C4^Zinc finger, C4 type (two domains)^101-167^E:8.8e-29",NA,NA,NA,NA,,
No,JO,LIF,DN522_c0_g1_i2,DN522_c0_g1,BCAS4_HUMAN,Breast carcinoma-amplified sequence 4,BCAS4_HUMAN,Breast carcinoma-amplified sequence 4,GO:0031083^cellular_component^BLOC-1 complex,NA,NA,NA,NA,GO:0031083^cellular_component^BLOC-1 complex,NA,NA,NA,NA,KEGG:hsa:55653`KO:K08366,ENOG410XVQ5^Breast carcinoma amplified sequence 4,.,NA,NA,NA,NA,,
No,JO,LIF,DN522_c0_g1_i1,DN522_c0_g1,BCAS4_HUMAN,Breast carcinoma-amplified sequence 4,BCAS4_HUMAN,Breast carcinoma-amplified sequence 4,GO:0031083^cellular_component^BLOC-1 complex,NA,NA,NA,NA,GO:0031083^cellular_component^BLOC-1 complex,NA,NA,NA,NA,KEGG:hsa:55653`KO:K08366,ENOG410XVQ5^Breast carcinoma amplified sequence 4,.,NA,NA,NA,NA,,
No,JO,LIF,DN8840_c0_g1_i5,DN8840_c0_g1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,KEGG:hsa:8537,ENOG41119UT^breast carcinoma amplified sequence 1,.,NA,NA,NA,NA,,
No,JO,LIF,DN8840_c0_g1_i3,DN8840_c0_g1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,KEGG:hsa:8537,ENOG41119UT^breast carcinoma amplified sequence 1,.,NA,NA,NA,NA,,
No,JO,LIF,DN8840_c0_g1_i2,DN8840_c0_g1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,KEGG:hsa:8537,ENOG41119UT^breast carcinoma amplified sequence 1,.,NA,NA,NA,NA,,
No,JO,LIF,DN8840_c0_g1_i8,DN8840_c0_g1,BCAS1_MOUSE,Breast carcinoma-amplified sequence 1 homolog,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0014069^cellular_component^postsynaptic density,GO:0042803^molecular_function^protein homodimerization activity,GO:0042552^biological_process^myelination,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,KEGG:hsa:8537,ENOG41119UT^breast carcinoma amplified sequence 1,.,NA,NA,NA,NA,,
No,JO,LIF,DN8840_c0_g1_i9,DN8840_c0_g1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,BCAS1_HUMAN,Breast carcinoma-amplified sequence 1,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0014069^cellular_component^postsynaptic density,GO:0042552^biological_process^myelination,NA,KEGG:hsa:8537,ENOG41119UT^breast carcinoma amplified sequence 1,.,NA,NA,NA,NA,,
No,JO,LIF,DN18044_c0_g1_i2,DN18044_c0_g1,PPDPF_XENTR,Pancreatic progenitor cell differentiation and proliferation factor,.,NA,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xtr:100037910,ENOG4111Z27^Pancreatic progenitor cell differentiation and proliferation factor homolog (Zebrafish),.,NA,NA,NA,NA,,
No,JO,LIF,DN18044_c0_g1_i10,DN18044_c0_g1,PPDPF_XENTR,Pancreatic progenitor cell differentiation and proliferation factor,PPDPF_XENTR,Pancreatic progenitor cell differentiation and proliferation factor,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,KEGG:xtr:100037910,ENOG4111Z27^Pancreatic progenitor cell differentiation and proliferation factor homolog (Zebrafish),PF15060.6^PPDFL^Differentiation and proliferation regulator^72-137^E:5.1e-25,NA,NA,NA,NA,,
No,JO,LIF,DN18044_c0_g1_i9,DN18044_c0_g1,PPDPF_XENTR,Pancreatic progenitor cell differentiation and proliferation factor,.,NA,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,.,NA,NA,NA,NA,KEGG:xtr:100037910,ENOG4111Z27^Pancreatic progenitor cell differentiation and proliferation factor homolog (Zebrafish),.,NA,NA,NA,NA,,
no,AD,LIF,DN18044_c0_g1_i8,DN18044_c0_g1,.,NA,PDPFA_XENLA,Pancreatic progenitor cell differentiation and proliferation factor A,.,NA,NA,NA,NA,GO:0030154^biological_process^cell differentiation,GO:0007275^biological_process^multicellular organism development,NA,NA,NA,KEGG:xla:379077,.,PF15060.6^PPDFL^Differentiation and proliferation regulator^55-98^E:1.9e-18,NA,NA,NA,NA,,
no,AD,LIF,DN6197_c0_g1_i6,DN6197_c0_g1,LFG1_HUMAN,Protein lifeguard 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0044325^molecular_function^ion channel binding,GO:0032469^biological_process^endoplasmic reticulum calcium ion homeostasis,.,NA,NA,NA,NA,KEGG:hsa:2907`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN56386_c0_g1_i9,DN56386_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN56386_c0_g1_i8,DN56386_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN56386_c0_g1_i2,DN56386_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN2472_c0_g1_i7,DN2472_c0_g1,MCTS1_CHICK,Malignant T-cell-amplified sequence 1,MCTS1_CHICK,Malignant T-cell-amplified sequence 1,GO:0022627^cellular_component^cytosolic small ribosomal subunit,GO:0003723^molecular_function^RNA binding,GO:0007049^biological_process^cell cycle,GO:0001731^biological_process^formation of translation preinitiation complex,GO:0040008^biological_process^regulation of growth,GO:0022627^cellular_component^cytosolic small ribosomal subunit,GO:0003723^molecular_function^RNA binding,GO:0007049^biological_process^cell cycle,GO:0001731^biological_process^formation of translation preinitiation complex,GO:0040008^biological_process^regulation of growth,KEGG:gga:422363`KO:K07575,COG2016^Rna-binding protein,PF17832.1^Pre-PUA^Pre-PUA-like domain^5-89^E:1.2e-25,PF01472.20^PUA^PUA domain^94-155^E:2.2e-15,NA,NA,NA,,
no,AD,LIF,DN2472_c0_g1_i8,DN2472_c0_g1,MCTS1_CHICK,Malignant T-cell-amplified sequence 1,.,NA,GO:0022627^cellular_component^cytosolic small ribosomal subunit,GO:0003723^molecular_function^RNA binding,GO:0007049^biological_process^cell cycle,GO:0001731^biological_process^formation of translation preinitiation complex,GO:0040008^biological_process^regulation of growth,.,NA,NA,NA,NA,KEGG:gga:422363`KO:K07575,COG2016^Rna-binding protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN28515_c0_g1_i1,DN28515_c0_g1,PPARD_HUMAN,Peroxisome proliferator-activated receptor delta,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:hsa:5467`KO:K04504,ENOG410XRZC^receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN69396_c0_g1_i2,DN69396_c0_g1,TES_CHICK,Testin,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005925^cellular_component^focal adhesion,GO:0008270^molecular_function^zinc ion binding,GO:0042127^biological_process^regulation of cell population proliferation,NA,.,NA,NA,NA,NA,KEGG:gga:395332,"ENOG410XQU0^Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor",.,NA,NA,NA,NA,,
yes,AD,LIF,DN10589_c0_g1_i12,DN10589_c0_g1,LIFR_CANLF,Leukemia inhibitory factor receptor,OSMR_HUMAN,Oncostatin-M-specific receptor subunit beta,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043235^cellular_component^receptor complex,GO:0005127^molecular_function^ciliary neurotrophic factor receptor binding,GO:0019955^molecular_function^cytokine binding,GO:0016324^cellular_component^apical plasma membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005900^cellular_component^oncostatin-M receptor complex,GO:0005886^cellular_component^plasma membrane,GO:0043235^cellular_component^receptor complex,KEGG:hsa:9180`KO:K05057,ENOG410Y9XY^oncostatin M receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN9585_c0_g1_i3,DN9585_c0_g1,.,NA,LFG1_BOVIN,Protein lifeguard 1,.,NA,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,KEGG:bta:510225`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN9585_c0_g1_i5,DN9585_c0_g1,.,NA,LFG1_RAT,Protein lifeguard 1,.,NA,NA,NA,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0005261^molecular_function^cation channel activity,GO:0044325^molecular_function^ion channel binding,KEGG:rno:266668`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN1850_c0_g3_i1,DN1850_c0_g3,M126_CHICK,Protein MRP-126,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0050786^molecular_function^RAGE receptor binding,GO:0061844^biological_process^antimicrobial humoral immune response mediated by antimicrobial peptide,.,NA,NA,NA,NA,KEGG:gga:426356`KO:K21128,"ENOG4111C30^S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K AKT, and ERK1 2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8 A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH- oxidase by facilitating the enzyme complex assembly at the cell membrane, transfering arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2 P67PHOX. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF- kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2 ) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect",.,NA,NA,NA,NA,,
no,AD,LIF,DN51347_c0_g1_i1,DN51347_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN51347_c0_g1_i2,DN51347_c0_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN1035_c3_g1_i2,DN1035_c3_g1,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,.,NA,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,.,NA,NA,NA,NA,KEGG:hsa:26037`KO:K17701,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
Yes,AD,LIF,DN376_c0_g1_i9,DN376_c0_g1,IL15_HUMAN,Interleukin-15,IL15_HUMAN,Interleukin-15,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005768^cellular_component^endosome,GO:0005576^cellular_component^extracellular region,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005768^cellular_component^endosome,GO:0005576^cellular_component^extracellular region,KEGG:hsa:3600`KO:K05433,"ENOG41119SX^Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha",PF02372.15^IL15^Interleukin 15^55-99^E:1.7e-11,NA,NA,NA,NA,,
no,AD,LIF,DN5816_c0_g1_i5,DN5816_c0_g1,.,NA,PDPN_HUMAN,Podoplanin {ECO:0000303|Ref.9},.,NA,NA,NA,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0030054^cellular_component^cell junction,GO:0042995^cellular_component^cell projection,GO:0031410^cellular_component^cytoplasmic vesicle,KEGG:hsa:10630`KO:K16778,"ENOG41116TP^May be involved in cell migration and or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels",PF05808.11^Podoplanin^Podoplanin^23-145^E:9.9e-25,NA,NA,NA,NA,,
no,AD,LIF,DN5816_c0_g1_i4,DN5816_c0_g1,.,NA,PDPN_HUMAN,Podoplanin {ECO:0000303|Ref.9},.,NA,NA,NA,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0016323^cellular_component^basolateral plasma membrane,GO:0030054^cellular_component^cell junction,GO:0042995^cellular_component^cell projection,GO:0031410^cellular_component^cytoplasmic vesicle,KEGG:hsa:10630`KO:K16778,"ENOG41116TP^May be involved in cell migration and or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels",PF05808.11^Podoplanin^Podoplanin^23-147^E:7.2e-27,NA,NA,NA,NA,,
no,AD,LIF,DN44569_c0_g1_i2,DN44569_c0_g1,PPARD_CANLF,Peroxisome proliferator-activated receptor delta,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:cfa:481756`KO:K04504,ENOG410XRZC^receptor,.,NA,NA,NA,NA,,
no,AD,LIF,DN5392_c1_g1_i1,DN5392_c1_g1,PA2G4_MOUSE,Proliferation-associated protein 2G4,PA2G4_HUMAN,Proliferation-associated protein 2G4,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003677^molecular_function^DNA binding,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),PF00557.24^Peptidase_M24^Metallopeptidase family M24^46-190^E:4.5e-21,NA,NA,NA,NA,,
no,AD,LIF,DN5392_c1_g1_i2,DN5392_c1_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,PA2G4_HUMAN,Proliferation-associated protein 2G4,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),PF00557.24^Peptidase_M24^Metallopeptidase family M24^46-253^E:5.8e-23,NA,NA,NA,NA,,
no,AD,LIF,DN5392_c1_g1_i3,DN5392_c1_g1,PA2G4_HUMAN,Proliferation-associated protein 2G4,.,NA,GO:0035578^cellular_component^azurophil granule lumen,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:5036,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN67396_c0_g1_i2,DN67396_c0_g1,PA2G4_MOUSE,Proliferation-associated protein 2G4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:mmu:18813,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN67396_c0_g1_i3,DN67396_c0_g1,PA2G4_MOUSE,Proliferation-associated protein 2G4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:mmu:18813,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN149520_c0_g2_i2,DN149520_c0_g2,LFG3_HUMAN,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0070062^cellular_component^extracellular exosome,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,.,NA,NA,NA,NA,KEGG:hsa:64114`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN149520_c1_g1_i2,DN149520_c1_g1,LFG3_MOUSE,Protein lifeguard 3,.,NA,GO:0010008^cellular_component^endosome membrane,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005765^cellular_component^lysosomal membrane,.,NA,NA,NA,NA,KEGG:mmu:69660`KO:K06890,COG0670^Membrane,.,NA,NA,NA,NA,,
no,AD,LIF,DN171340_c2_g1_i1,DN171340_c2_g1,MCTS1_CHICK,Malignant T-cell-amplified sequence 1,.,NA,GO:0022627^cellular_component^cytosolic small ribosomal subunit,GO:0003723^molecular_function^RNA binding,GO:0007049^biological_process^cell cycle,GO:0001731^biological_process^formation of translation preinitiation complex,GO:0040008^biological_process^regulation of growth,.,NA,NA,NA,NA,KEGG:gga:422363`KO:K07575,COG2016^Rna-binding protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN115279_c0_g1_i1,DN115279_c0_g1,SI1L1_HUMAN,Signal-induced proliferation-associated 1-like protein 1,.,NA,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005856^cellular_component^cytoskeleton,GO:0043197^cellular_component^dendritic spine,GO:0014069^cellular_component^postsynaptic density,.,NA,NA,NA,NA,KEGG:hsa:26037`KO:K17701,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN122499_c0_g1_i1,DN122499_c0_g1,BCAS3_MOUSE,Breast carcinoma-amplified sequence 3 homolog {ECO:0000250|UniProtKB:Q9H6U6},.,NA,GO:0031252^cellular_component^cell leading edge,GO:0071944^cellular_component^cell periphery,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0045111^cellular_component^intermediate filament cytoskeleton,.,NA,NA,NA,NA,KEGG:mmu:192197,ENOG410XSW7^Breast carcinoma amplified sequence,.,NA,NA,NA,NA,,
no,AD,LIF,DN143292_c0_g1_i6,DN143292_c0_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,.,NA,NA,NA,NA,,
no,AD,LIF,DN143292_c0_g1_i1,DN143292_c0_g1,MFHA1_XENTR,Malignant fibrous histiocytoma-amplified sequence 1 homolog {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0006954^biological_process^inflammatory response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,KEGG:xtr:100125009,COG4886^leucine Rich Repeat,.,NA,NA,NA,NA,,
no,AD,LIF,DN198145_c0_g1_i1,DN198145_c0_g1,PA2G4_MOUSE,Proliferation-associated protein 2G4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:mmu:18813,COG0024^Removes the N-terminal methionine from nascent proteins (By similarity),.,NA,NA,NA,NA,,
no,AD,LIF,DN210413_c0_g1_i1,DN210413_c0_g1,SI1L2_HUMAN,Signal-induced proliferation-associated 1-like protein 2,.,NA,GO:0005096^molecular_function^GTPase activator activity,GO:0051056^biological_process^regulation of small GTPase mediated signal transduction,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:57568`KO:K17702,ENOG410XTIX^gtpase activating protein,.,NA,NA,NA,NA,,
no,AD,LIF,DN347196_c0_g1_i1,DN347196_c0_g1,M126_CHICK,Protein MRP-126,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005509^molecular_function^calcium ion binding,GO:0050786^molecular_function^RAGE receptor binding,GO:0061844^biological_process^antimicrobial humoral immune response mediated by antimicrobial peptide,.,NA,NA,NA,NA,KEGG:gga:426356`KO:K21128,"ENOG4111C30^S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K AKT, and ERK1 2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8 A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH- oxidase by facilitating the enzyme complex assembly at the cell membrane, transfering arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2 P67PHOX. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF- kappa-B signaling pathways resulting in the amplification of the proinflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2 ) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect",.,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i7,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-111^E:1.9e-10,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i6,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-144^E:2.5e-25,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i2,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-144^E:2.5e-25,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i1,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-111^E:1.9e-10,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i8,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-144^E:2.5e-25,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i5,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-144^E:2.5e-25,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i4,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,.,NA,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,.,NA,NA,NA,NA,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,.,NA,NA,NA,NA,,
yes,AD,LITAF,DN4777_c0_g1_i3,DN4777_c0_g1,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_CHICK,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:gga:374125`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^75-144^E:2.5e-25,NA,NA,NA,NA,,
yes,AD,LITAF,DN452651_c0_g1_i1,DN452651_c0_g1,LITAF_RAT,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,LITAF_XENTR,Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0005829^cellular_component^cytosol,GO:0098559^cellular_component^cytoplasmic side of early endosome membrane,GO:0098560^cellular_component^cytoplasmic side of late endosome membrane,GO:0098574^cellular_component^cytoplasmic side of lysosomal membrane,GO:0009898^cellular_component^cytoplasmic side of plasma membrane,GO:0000139^cellular_component^Golgi membrane,KEGG:xtr:394567`KO:K19363,ENOG41122PJ^lipopolysaccharide-induced TNF factor,PF10601.9^zf-LITAF-like^LITAF-like zinc ribbon domain^67-136^E:1.1e-18,NA,NA,NA,NA,,
yes,AD,LY6E,DN7889_c0_g1_i1,DN7889_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN7889_c0_g1_i2,DN7889_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN7889_c0_g2_i2,DN7889_c0_g2,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN7889_c0_g2_i3,DN7889_c0_g2,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN49878_c0_g1_i2,DN49878_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,LY6E_CHICK,Lymphocyte antigen 6E,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^23-97^E:3.6e-08,PF00087.21^Toxin_TOLIP^Snake toxin and toxin-like protein^24-97^E:8.3e-08,NA,NA,NA,,
yes,AD,LY6E,DN13896_c0_g1_i5,DN13896_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,LY6E_CHICK,Lymphocyte antigen 6E,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",PF00087.21^Toxin_TOLIP^Snake toxin and toxin-like protein^46-120^E:9.8e-11,PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^47-120^E:4.2e-09,NA,NA,NA,,
yes,AD,LY6E,DN13896_c0_g1_i3,DN13896_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN13896_c0_g1_i1,DN13896_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN13896_c0_g1_i2,DN13896_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN13500_c0_g2_i2,DN13500_c0_g2,LY6E_CHICK,Lymphocyte antigen 6E,LY6E_CHICK,Lymphocyte antigen 6E,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",PF00087.21^Toxin_TOLIP^Snake toxin and toxin-like protein^22-96^E:3.4e-13,PF00021.21^UPAR_LY6^u-PAR/Ly-6 domain^23-96^E:3.3e-10,NA,NA,NA,,
yes,AD,LY6E,DN13500_c0_g2_i1,DN13500_c0_g2,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
yes,AD,LY6E,DN183393_c0_g1_i1,DN183393_c0_g1,LY6E_CHICK,Lymphocyte antigen 6E,.,NA,GO:0031225^cellular_component^anchored component of membrane,GO:0009986^cellular_component^cell surface,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030550^molecular_function^acetylcholine receptor inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:395550`KO:K06846,"ENOG4111AYX^lymphocyte antigen 6 complex, locus E",.,NA,NA,NA,NA,,
no,AD,MHC,DN8718_c0_g1_i4,DN8718_c0_g1,NHLC1_HUMAN,E3 ubiquitin-protein ligase NHLRC1,NHLC1_HUMAN,E3 ubiquitin-protein ligase NHLRC1,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0046872^molecular_function^metal ion binding,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0046872^molecular_function^metal ion binding,KEGG:hsa:378884`KO:K10602,ENOG410ZMHC^NHL repeat containing 1,PF14634.6^zf-RING_5^zinc-RING finger domain^34-80^E:5e-09,PF13639.6^zf-RING_2^Ring finger domain^34-79^E:5.2e-08,PF13445.6^zf-RING_UBOX^RING-type zinc-finger^35-76^E:1.7e-07,"PF00097.25^zf-C3HC4^Zinc finger, C3HC4 type (RING finger)^35-78^E:5.8e-06",NA,,
Yes,JO,MHC,DN265_c6_g1_i1,DN265_c6_g1,HMR1_PANTR,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,.,NA,NA,NA,NA,KEGG:ptr:457562,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN38847_c0_g1_i2,DN38847_c0_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,.,NA,NA,NA,NA,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN3261_c0_g1_i5,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,.,NA,NA,NA,NA,KEGG:hsa:4261`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN3261_c0_g1_i1,DN3261_c0_g1,C2TA_MOUSE,MHC class II transactivator,C2TA_MOUSE,MHC class II transactivator,GO:0009986^cellular_component^cell surface,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,GO:0009986^cellular_component^cell surface,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,KEGG:mmu:12265`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,PF05729.12^NACHT^NACHT domain^470-638^E:4.1e-34,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^779-887^E:9.4e-12,PF13516.6^LRR_6^Leucine Rich repeat^924-940^E:2700,PF13516.6^LRR_6^Leucine Rich repeat^1062-1076^E:0.17,PF13516.6^LRR_6^Leucine Rich repeat^1083-1104^E:8.6e-05,,
Yes,JO,MHC,DN3261_c0_g1_i16,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,.,NA,NA,NA,NA,KEGG:hsa:4261`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN3261_c0_g1_i4,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,C2TA_MOUSE,MHC class II transactivator,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,GO:0009986^cellular_component^cell surface,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,KEGG:mmu:12265`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,PF05729.12^NACHT^NACHT domain^389-557^E:3.8e-34,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^698-806^E:8.8e-12,PF13516.6^LRR_6^Leucine Rich repeat^843-859^E:2000,PF00560.33^LRR_1^Leucine Rich Repeat^972-994^E:450,PF13516.6^LRR_6^Leucine Rich repeat^981-995^E:0.18,,
Yes,JO,MHC,DN3261_c0_g1_i10,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,.,NA,NA,NA,NA,KEGG:hsa:4261`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN3261_c0_g1_i17,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,C2TA_MOUSE,MHC class II transactivator,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,GO:0009986^cellular_component^cell surface,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,KEGG:mmu:12265`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,PF05729.12^NACHT^NACHT domain^364-532^E:3.6e-34,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^673-781^E:8.2e-12,PF13516.6^LRR_6^Leucine Rich repeat^818-834^E:1900,PF13516.6^LRR_6^Leucine Rich repeat^956-970^E:0.17,PF13516.6^LRR_6^Leucine Rich repeat^977-998^E:7.7e-05,,
Yes,JO,MHC,DN3261_c0_g1_i8,DN3261_c0_g1,C2TA_HUMAN,MHC class II transactivator,C2TA_HUMAN,MHC class II transactivator,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,GO:0005654^cellular_component^nucleoplasm,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,KEGG:hsa:4261`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,PF05729.12^NACHT^NACHT domain^89-257^E:1.7e-34,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^398-506^E:4.4e-12,NA,NA,NA,,
Yes,JO,MHC,DN2354_c0_g2_i1,DN2354_c0_g2,RFX1_HUMAN,MHC class II regulatory factor RFX1,.,NA,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:hsa:5989`KO:K09173,ENOG410XSHE^influences HLA class II expression,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN20425_c0_g1_i1,DN20425_c0_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,.,NA,NA,NA,NA,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN20425_c0_g1_i4,DN20425_c0_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,HMR1_RAT,Major histocompatibility complex class I-related gene protein,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,"PF00129.18^MHC_I^Class I Histocompatibility antigen, domains alpha 1 and 2^45-101^E:7.3e-20",NA,NA,NA,NA,,
Yes,JO,MHC,DN9599_c0_g2_i1,DN9599_c0_g2,RFX1_HUMAN,MHC class II regulatory factor RFX1,RFX1_HUMAN,MHC class II regulatory factor RFX1,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:hsa:5989`KO:K09173,ENOG410XSHE^influences HLA class II expression,PF04589.13^RFX1_trans_act^RFX1 transcription activation region^6-122^E:8.7e-32,NA,NA,NA,NA,,
Yes,JO,MHC,DN31649_c0_g1_i1,DN31649_c0_g1,HMR1_PONAB,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0002367^biological_process^cytokine production involved in immune response,.,NA,NA,NA,NA,KEGG:pon:100172054,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN20069_c0_g1_i13,DN20069_c0_g1,HMR1_PONAB,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0002474^biological_process^antigen processing and presentation of peptide antigen via MHC class I,GO:0002367^biological_process^cytokine production involved in immune response,.,NA,NA,NA,NA,KEGG:pon:100172054,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN20069_c0_g1_i14,DN20069_c0_g1,HA1F_CHICK,"Class I histocompatibility antigen, F10 alpha chain",HMR1_HUMAN,Major histocompatibility complex class I-related gene protein,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0005886^cellular_component^plasma membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:3140,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,"PF00129.18^MHC_I^Class I Histocompatibility antigen, domains alpha 1 and 2^75-114^E:3.1e-11",NA,NA,NA,NA,,
Yes,JO,MHC,DN20069_c0_g1_i15,DN20069_c0_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,.,NA,NA,NA,NA,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN32094_c1_g1_i3,DN32094_c1_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,.,NA,NA,NA,NA,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,.,NA,NA,NA,NA,,
Yes,JO,MHC,DN32094_c1_g1_i6,DN32094_c1_g1,HMR1_RAT,Major histocompatibility complex class I-related gene protein,HA1F_CHICK,"Class I histocompatibility antigen, F10 alpha chain",GO:0005783^cellular_component^endoplasmic reticulum,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0009897^cellular_component^external side of plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0042612^cellular_component^MHC class I protein complex,GO:0005886^cellular_component^plasma membrane,KEGG:rno:25119,ENOG4111K8F^antigen processing and presentation of peptide antigen via MHC class I,"PF00129.18^MHC_I^Class I Histocompatibility antigen, domains alpha 1 and 2^90-133^E:3.3e-11",NA,NA,NA,NA,,
Yes,JO,MHC,DN116860_c0_g1_i1,DN116860_c0_g1,C2TA_MOUSE,MHC class II transactivator,.,NA,GO:0009986^cellular_component^cell surface,GO:0016605^cellular_component^PML body,GO:0033613^molecular_function^activating transcription factor binding,GO:0005524^molecular_function^ATP binding,GO:0005525^molecular_function^GTP binding,.,NA,NA,NA,NA,KEGG:mmu:12265`KO:K08060,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,MSTN,DN96_c0_g1_i4,DN96_c0_g1,MSTN1_CHICK,Musculoskeletal embryonic nuclear protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0002062^biological_process^chondrocyte differentiation,GO:0035988^biological_process^chondrocyte proliferation,GO:0032332^biological_process^positive regulation of chondrocyte differentiation,GO:1902732^biological_process^positive regulation of chondrocyte proliferation,.,NA,NA,NA,NA,KEGG:gga:404773,"ENOG410YWMF^musculoskeletal, embryonic nuclear protein 1",.,NA,NA,NA,NA,,
yes,AD,MSTN,DN96_c0_g1_i1,DN96_c0_g1,MSTN1_CHICK,Musculoskeletal embryonic nuclear protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0002062^biological_process^chondrocyte differentiation,GO:0035988^biological_process^chondrocyte proliferation,GO:0032332^biological_process^positive regulation of chondrocyte differentiation,GO:1902732^biological_process^positive regulation of chondrocyte proliferation,.,NA,NA,NA,NA,KEGG:gga:404773,"ENOG410YWMF^musculoskeletal, embryonic nuclear protein 1",.,NA,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i11,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:mmu:12169`KO:K08896,COG0515^Serine Threonine protein kinase,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^4-109^E:6.9e-36,PF00069.25^Pkinase^Protein kinase domain^21-107^E:1.9e-10,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i13,DN2916_c0_g1,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:mmu:12169`KO:K08896,COG0515^Serine Threonine protein kinase,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^4-109^E:6.9e-36,PF00069.25^Pkinase^Protein kinase domain^21-107^E:1.9e-10,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i9,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^32-114^E:3e-24,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^155-275^E:1.5e-38,PF00069.25^Pkinase^Protein kinase domain^157-274^E:5.9e-23,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i12,DN2916_c0_g1,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:12169`KO:K08896,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i8,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^25-145^E:2.7e-39,PF00069.25^Pkinase^Protein kinase domain^27-144^E:1e-23,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i5,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^3-37^E:7.7e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^78-325^E:2.4e-93,PF00069.25^Pkinase^Protein kinase domain^80-323^E:1.7e-45,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i7,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^3-37^E:7.5e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^78-319^E:1.9e-92,PF00069.25^Pkinase^Protein kinase domain^80-319^E:6.8e-45,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i1,DN2916_c0_g1,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:12169`KO:K08896,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,MX,DN2916_c0_g1_i4,DN2916_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,PF00169.29^PH^PH domain^7-110^E:1.2e-18,PF00779.19^BTK^BTK motif^119-147^E:3.5e-11,PF00018.28^SH3_1^SH3 domain^191-236^E:4.2e-05,NA,NA,,
no,AD,MX,DN18982_c0_g1_i6,DN18982_c0_g1,CPLX1_RAT,Complexin-1,CPLX1_RAT,Complexin-1,GO:0044305^cellular_component^calyx of Held,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0043025^cellular_component^neuronal cell body,GO:0044305^cellular_component^calyx of Held,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0043025^cellular_component^neuronal cell body,KEGG:rno:64832`KO:K15294,ENOG4111MX0^Complexin,PF05835.12^Synaphin^Synaphin protein^1-131^E:8.1e-41,NA,NA,NA,NA,,
no,AD,MX,DN8773_c0_g4_i1,DN8773_c0_g4,PRP2_SOYBN,Repetitive proline-rich cell wall protein 2,.,NA,GO:0005618^cellular_component^cell wall,GO:0005576^cellular_component^extracellular region,GO:0005199^molecular_function^structural constituent of cell wall,GO:0007275^biological_process^multicellular organism development,NA,.,NA,NA,NA,NA,KEGG:gmx:547830,.,.,NA,NA,NA,NA,,
no,AD,MX,DN5132_c3_g1_i6,DN5132_c3_g1,TMX3_XENLA,Protein disulfide-isomerase TMX3,TMX3_XENLA,Protein disulfide-isomerase TMX3,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0045454^biological_process^cell redox homeostasis,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0045454^biological_process^cell redox homeostasis,NA,KEGG:xla:444355`KO:K09585,.,.,NA,NA,NA,NA,,
no,AD,MX,DN5132_c3_g1_i10,DN5132_c3_g1,TMX3_MOUSE,Protein disulfide-isomerase TMX3,TMX3_HUMAN,Protein disulfide-isomerase TMX3,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0016972^molecular_function^thiol oxidase activity,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,KEGG:hsa:54495`KO:K09585,COG0526^Thioredoxin,PF00085.20^Thioredoxin^Thioredoxin^48-143^E:5.3e-25,PF13848.6^Thioredoxin_6^Thioredoxin-like domain^176-353^E:8.8e-25,NA,NA,NA,,
no,AD,MX,DN5132_c3_g1_i7,DN5132_c3_g1,TMX3_MOUSE,Protein disulfide-isomerase TMX3,TMX3_HUMAN,Protein disulfide-isomerase TMX3,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0016972^molecular_function^thiol oxidase activity,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,KEGG:hsa:54495`KO:K09585,COG0526^Thioredoxin,PF00085.20^Thioredoxin^Thioredoxin^1-80^E:4.4e-22,NA,NA,NA,NA,,
no,AD,MX,DN5132_c3_g1_i3,DN5132_c3_g1,TMX3_HUMAN,Protein disulfide-isomerase TMX3,TMX3_HUMAN,Protein disulfide-isomerase TMX3,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,KEGG:hsa:54495`KO:K09585,COG0526^Thioredoxin,PF00085.20^Thioredoxin^Thioredoxin^7-58^E:2e-07,PF13848.6^Thioredoxin_6^Thioredoxin-like domain^91-268^E:5.7e-25,NA,NA,NA,,
no,AD,MX,DN4215_c0_g1_i1,DN4215_c0_g1,MXI1_MOUSE,Max-interacting protein 1,MXI1_RAT,Max-interacting protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,GO:0090575^cellular_component^RNA polymerase II transcription factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046983^molecular_function^protein dimerization activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:mmu:17859`KO:K09114,"ENOG4111MIN^transcription, DNA-dependent",PF00010.26^HLH^Helix-loop-helix DNA-binding domain^103-154^E:1.5e-11,NA,NA,NA,NA,,
no,AD,MX,DN4215_c0_g1_i2,DN4215_c0_g1,MXI1_RAT,Max-interacting protein 1,MXI1_RAT,Max-interacting protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046983^molecular_function^protein dimerization activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046983^molecular_function^protein dimerization activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",.,"ENOG4111MIN^transcription, DNA-dependent",PF00010.26^HLH^Helix-loop-helix DNA-binding domain^127-178^E:1.8e-11,NA,NA,NA,NA,,
no,AD,MX,DN90007_c0_g1_i1,DN90007_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,.,NA,NA,NA,NA,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN78244_c0_g1_i1,DN78244_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",.,NA,NA,NA,NA,KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i9,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,PF06984.13^MRP-L47^Mitochondrial 39-S ribosomal protein L47 (MRP-L47)^75-160^E:3.7e-36,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i4,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i6,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,PF06984.13^MRP-L47^Mitochondrial 39-S ribosomal protein L47 (MRP-L47)^32-117^E:2.5e-36,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i5,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,.,NA,NA,NA,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i7,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i1,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,PF06984.13^MRP-L47^Mitochondrial 39-S ribosomal protein L47 (MRP-L47)^75-160^E:3.7e-36,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i8,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,PF06984.13^MRP-L47^Mitochondrial 39-S ribosomal protein L47 (MRP-L47)^1-39^E:1.9e-10,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g1_i3,DN11264_c0_g1,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,PF06984.13^MRP-L47^Mitochondrial 39-S ribosomal protein L47 (MRP-L47)^75-160^E:3.7e-36,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g2_i1,DN11264_c0_g2,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,.,NA,NA,NA,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g3_i1,DN11264_c0_g3,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,.,NA,NA,NA,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g4_i1,DN11264_c0_g4,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,.,NA,NA,NA,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11264_c0_g5_i1,DN11264_c0_g5,RM47_MOUSE,"39S ribosomal protein L47, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0032543^biological_process^mitochondrial translation,NA,.,NA,NA,NA,NA,KEGG:mmu:74600`KO:K17428,ENOG41121MX^(ribosomal) protein,.,NA,NA,NA,NA,,
no,AD,MX,DN5453_c1_g2_i1,DN5453_c1_g2,MXRA7_MOUSE,Matrix-remodeling-associated protein 7,.,NA,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:67622,ENOG410Y304^Matrix-remodelling associated 7,.,NA,NA,NA,NA,,
no,AD,MX,DN4551_c1_g1_i1,DN4551_c1_g1,CPLX2_RAT,Complexin-2,CPLX2_RAT,Complexin-2,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:116657`KO:K15294,ENOG4111MX0^Complexin,PF05835.12^Synaphin^Synaphin protein^1-131^E:1.3e-39,NA,NA,NA,NA,,
no,AD,MX,DN4551_c1_g1_i2,DN4551_c1_g1,CPLX2_RAT,Complexin-2,CPLX2_RAT,Complexin-2,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:116657`KO:K15294,ENOG4111MX0^Complexin,PF05835.12^Synaphin^Synaphin protein^1-131^E:1.3e-39,NA,NA,NA,NA,,
no,AD,MX,DN3658_c0_g1_i8,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,PF03456.18^uDENN^uDENN domain^309-372^E:1.8e-14,PF02141.21^DENN^DENN (AEX-3) domain^408-590^E:5.9e-63,PF03455.19^dDENN^dDENN domain^697-746^E:6.2e-13,PF01535.20^PPR^PPR repeat^919-949^E:0.18,NA,,
no,AD,MX,DN3658_c0_g1_i3,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN3658_c0_g1_i1,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN3658_c0_g1_i4,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,PF03456.18^uDENN^uDENN domain^309-372^E:3.7e-14,PF02141.21^DENN^DENN (AEX-3) domain^408-590^E:1.4e-62,PF03455.19^dDENN^dDENN domain^697-746^E:1.2e-12,PF01535.20^PPR^PPR repeat^919-949^E:0.36,NA,,
no,AD,MX,DN3658_c0_g1_i5,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN3658_c0_g1_i7,DN3658_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,DEN4C_HUMAN,DENN domain-containing protein 4C,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN15069_c0_g1_i3,DN15069_c0_g1,HMX3_CHICK,Homeobox protein HMX3,.,NA,GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0030154^biological_process^cell differentiation,GO:0007399^biological_process^nervous system development,"GO:0006355^biological_process^regulation of transcription, DNA-templated",.,NA,NA,NA,NA,KEGG:gga:429199`KO:K09349,ENOG4111R8D^H6 family homeobox,.,NA,NA,NA,NA,,
no,AD,MX,DN15069_c0_g1_i1,DN15069_c0_g1,HMX3_CHICK,Homeobox protein HMX3,HMX3_DANRE,Homeobox protein HMX3,GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0030154^biological_process^cell differentiation,GO:0007399^biological_process^nervous system development,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0030154^biological_process^cell differentiation,GO:0042472^biological_process^inner ear morphogenesis,GO:0007399^biological_process^nervous system development,KEGG:gga:429199`KO:K09349,ENOG4111R8D^H6 family homeobox,PF00046.29^Homeodomain^Homeodomain^2-37^E:1.4e-14,NA,NA,NA,NA,,
no,AD,MX,DN15069_c1_g1_i1,DN15069_c1_g1,HMX2_MOUSE,Homeobox protein HMX2,HMX2_HUMAN,Homeobox protein HMX2,GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,GO:0042472^biological_process^inner ear morphogenesis,GO:0000790^cellular_component^nuclear chromatin,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,KEGG:hsa:3167`KO:K09349,ENOG4111R8D^H6 family homeobox,PF00046.29^Homeodomain^Homeodomain^1-42^E:1.7e-15,NA,NA,NA,NA,,
no,AD,MX,DN15069_c1_g2_i1,DN15069_c1_g2,HMX2_HUMAN,Homeobox protein HMX2,HMX2_MOUSE,Homeobox protein HMX2,GO:0000790^cellular_component^nuclear chromatin,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,GO:0042472^biological_process^inner ear morphogenesis,KEGG:mmu:15372`KO:K09349,ENOG4111R8D^H6 family homeobox,.,NA,NA,NA,NA,,
no,AD,MX,DN15069_c1_g2_i2,DN15069_c1_g2,HMX2_HUMAN,Homeobox protein HMX2,HMX2_MOUSE,Homeobox protein HMX2,GO:0000790^cellular_component^nuclear chromatin,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,GO:0005634^cellular_component^nucleus,GO:0043565^molecular_function^sequence-specific DNA binding,GO:0007420^biological_process^brain development,GO:0030154^biological_process^cell differentiation,GO:0042472^biological_process^inner ear morphogenesis,KEGG:mmu:15372`KO:K09349,ENOG4111R8D^H6 family homeobox,.,NA,NA,NA,NA,,
no,AD,MX,DN6731_c0_g1_i6,DN6731_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,MYCPP_HUMAN,C-myc promoter-binding protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,PF03456.18^uDENN^uDENN domain^211-274^E:2e-16,PF02141.21^DENN^DENN (AEX-3) domain^309-492^E:8.7e-62,PF03455.19^dDENN^dDENN domain^599-648^E:4e-14,PF13812.6^PPR_3^Pentatricopeptide repeat domain^796-849^E:0.00086,PF01535.20^PPR^PPR repeat^811-841^E:0.047,,
no,AD,MX,DN6731_c0_g1_i2,DN6731_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,MYCPP_HUMAN,C-myc promoter-binding protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN6731_c0_g1_i8,DN6731_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,MYCPP_HUMAN,C-myc promoter-binding protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,PF03456.18^uDENN^uDENN domain^211-274^E:2.1e-16,PF02141.21^DENN^DENN (AEX-3) domain^309-492^E:9.6e-62,PF03455.19^dDENN^dDENN domain^599-648^E:4.3e-14,PF13812.6^PPR_3^Pentatricopeptide repeat domain^796-849^E:0.00095,PF01535.20^PPR^PPR repeat^811-841^E:0.051,,
no,AD,MX,DN6731_c0_g1_i9,DN6731_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,MYCPP_HUMAN,C-myc promoter-binding protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,PF03456.18^uDENN^uDENN domain^211-274^E:2.1e-16,PF02141.21^DENN^DENN (AEX-3) domain^309-492^E:9.6e-62,PF03455.19^dDENN^dDENN domain^599-648^E:4.3e-14,PF13812.6^PPR_3^Pentatricopeptide repeat domain^796-849^E:0.00095,PF01535.20^PPR^PPR repeat^811-841^E:0.051,,
no,AD,MX,DN6731_c0_g1_i4,DN6731_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,MYCPP_HUMAN,C-myc promoter-binding protein,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN21760_c0_g1_i1,DN21760_c0_g1,TMX3_XENLA,Protein disulfide-isomerase TMX3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0045454^biological_process^cell redox homeostasis,NA,.,NA,NA,NA,NA,KEGG:xla:444355`KO:K09585,.,.,NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i9,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",PF00852.19^Glyco_transf_10^Glycosyltransferase family 10 (fucosyltransferase) C-term^83-232^E:2.5e-36,NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i12,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",.,NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i15,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",.,NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i16,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",PF00852.19^Glyco_transf_10^Glycosyltransferase family 10 (fucosyltransferase) C-term^3-93^E:2e-25,NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i10,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase","PF17039.5^Glyco_tran_10_N^Fucosyltransferase, N-terminal^5-50^E:4.1e-07",NA,NA,NA,NA,,
no,AD,MX,DN36265_c0_g1_i14,DN36265_c0_g1,FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",FUT11_CHICK,"Alpha-(1,3)-fucosyltransferase 11",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,KEGG:gga:395071`KO:K11257,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",PF00852.19^Glyco_transf_10^Glycosyltransferase family 10 (fucosyltransferase) C-term^1-124^E:6.5e-28,NA,NA,NA,NA,,
no,AD,MX,DN44505_c0_g1_i4,DN44505_c0_g1,LMX1B_CHICK,LIM/homeobox protein LMX-1.2,LMX1B_CHICK,LIM/homeobox protein LMX-1.2,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0072164^biological_process^mesonephric tubule development,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0072164^biological_process^mesonephric tubule development,KEGG:gga:396312`KO:K09371,ENOG410YIJ3^sequence-specific DNA binding,PF00412.22^LIM^LIM domain^56-110^E:7.7e-17,PF00412.22^LIM^LIM domain^115-172^E:1.1e-16,PF00046.29^Homeodomain^Homeodomain^219-275^E:9.7e-18,PF05920.11^Homeobox_KN^Homeobox KN domain^244-271^E:0.00029,NA,,
no,AD,MX,DN44505_c0_g1_i2,DN44505_c0_g1,LMX1B_CHICK,LIM/homeobox protein LMX-1.2,LMX1B_CHICK,LIM/homeobox protein LMX-1.2,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0072164^biological_process^mesonephric tubule development,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0072164^biological_process^mesonephric tubule development,KEGG:gga:396312`KO:K09371,ENOG410YIJ3^sequence-specific DNA binding,PF00412.22^LIM^LIM domain^56-109^E:2.5e-17,NA,NA,NA,NA,,
no,AD,MX,DN4321_c0_g1_i5,DN4321_c0_g1,PPR26_MOUSE,Protein phosphatase 1 regulatory subunit 26,PPR26_MOUSE,Protein phosphatase 1 regulatory subunit 26,GO:0005730^cellular_component^nucleolus,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0010923^biological_process^negative regulation of phosphatase activity,NA,NA,GO:0005730^cellular_component^nucleolus,GO:0004864^molecular_function^protein phosphatase inhibitor activity,GO:0010923^biological_process^negative regulation of phosphatase activity,NA,NA,KEGG:mmu:241289`KO:K17565,"ENOG4111MX8^protein phosphatase 1, regulatory subunit 26",PF15740.5^PPP1R26_N^Protein phosphatase 1 regulatory subunit 26 N-terminus^1-874^E:0,NA,NA,NA,NA,,
no,AD,MX,DN2548_c0_g1_i7,DN2548_c0_g1,TMX2_BOVIN,Thioredoxin-related transmembrane protein 2,TMX2_RAT,Thioredoxin-related transmembrane protein 2,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,KEGG:rno:295701,ENOG410XVTA^thioredoxin-related transmembrane protein,PF00085.20^Thioredoxin^Thioredoxin^17-105^E:4.3e-11,NA,NA,NA,NA,,
no,AD,MX,DN2548_c0_g1_i4,DN2548_c0_g1,TMX2_BOVIN,Thioredoxin-related transmembrane protein 2,.,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,.,NA,NA,NA,NA,KEGG:bta:509244,ENOG410XVTA^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN2548_c0_g1_i10,DN2548_c0_g1,TMX2_BOVIN,Thioredoxin-related transmembrane protein 2,.,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,.,NA,NA,NA,NA,KEGG:bta:509244,ENOG410XVTA^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN2548_c0_g1_i12,DN2548_c0_g1,TMX2_BOVIN,Thioredoxin-related transmembrane protein 2,TMX2_MACFA,Thioredoxin-related transmembrane protein 2,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,KEGG:mcf:101865953,ENOG410XVTA^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i1,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,P33MX_CHICK,Putative monooxygenase p33MONOX,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,KEGG:gga:416230,ENOG410YBU1^NA,PF15302.6^P33MONOX^P33 mono-oxygenase^9-184^E:4.4e-82,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i3,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,SIMC1_HUMAN,SUMO-interacting motif-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,GO:0032184^molecular_function^SUMO polymer binding,NA,NA,NA,NA,KEGG:hsa:375484,ENOG410XQXC^SUMO-interacting motifs containing 1,.,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i9,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:416230,ENOG410YBU1^NA,.,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i12,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:416230,ENOG410YBU1^NA,.,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i7,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,SIMC1_HUMAN,SUMO-interacting motif-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,GO:0032184^molecular_function^SUMO polymer binding,NA,NA,NA,NA,KEGG:hsa:375484,ENOG410XQXC^SUMO-interacting motifs containing 1,.,NA,NA,NA,NA,,
no,AD,MX,DN2547_c0_g1_i2,DN2547_c0_g1,P33MX_CHICK,Putative monooxygenase p33MONOX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016491^molecular_function^oxidoreductase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:gga:416230,ENOG410YBU1^NA,.,NA,NA,NA,NA,,
no,AD,MX,DN64795_c1_g1_i1,DN64795_c1_g1,DMXL1_MOUSE,DmX-like protein 1,.,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:240283,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN7446_c0_g1_i5,DN7446_c0_g1,DMXL1_HUMAN,DmX-like protein 1,DMXL1_HUMAN,DmX-like protein 1,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^860-1103^E:2.6e-08,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^1184-1563^E:1.5e-74,NA,NA,NA,,
no,AD,MX,DN7446_c0_g1_i1,DN7446_c0_g1,DMXL1_HUMAN,DmX-like protein 1,DMXL1_HUMAN,DmX-like protein 1,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,"PF00400.32^WD40^WD domain, G-beta repeat^144-179^E:0.078",PF12234.8^Rav1p_C^RAVE protein 1 C terminal^1106-1348^E:2.9e-08,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^1429-1808^E:1.8e-74,NA,NA,,
no,AD,MX,DN7446_c0_g1_i7,DN7446_c0_g1,DMXL1_MOUSE,DmX-like protein 1,.,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:240283,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN7446_c0_g1_i8,DN7446_c0_g1,DMXL1_HUMAN,DmX-like protein 1,DMXL1_HUMAN,DmX-like protein 1,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^228-471^E:2.1e-08,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^551-931^E:1.2e-74,"PF00400.32^WD40^WD domain, G-beta repeat^2044-2081^E:0.0063",NA,NA,,
no,AD,MX,DN7446_c0_g1_i3,DN7446_c0_g1,DMXL1_HUMAN,DmX-like protein 1,DMXL1_HUMAN,DmX-like protein 1,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^818-1061^E:2.5e-08,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^1142-1521^E:1.5e-74,NA,NA,NA,,
no,AD,MX,DN7446_c0_g1_i6,DN7446_c0_g1,DMXL1_MOUSE,DmX-like protein 1,DMXL1_HUMAN,DmX-like protein 1,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,"PF00400.32^WD40^WD domain, G-beta repeat^181-218^E:0.00055",NA,NA,NA,NA,,
no,AD,MX,DN77695_c0_g1_i3,DN77695_c0_g1,MXRA8_CHICK,Matrix remodeling-associated protein 8,MXRA8_CHICK,Matrix remodeling-associated protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,KEGG:gga:395347,ENOG41113W9^matrix-remodelling associated 8,.,NA,NA,NA,NA,,
no,AD,MX,DN77695_c0_g1_i2,DN77695_c0_g1,MXRA8_CHICK,Matrix remodeling-associated protein 8,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,.,NA,NA,NA,NA,KEGG:gga:395347,ENOG41113W9^matrix-remodelling associated 8,.,NA,NA,NA,NA,,
no,AD,MX,DN2895_c0_g1_i3,DN2895_c0_g1,RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",KEGG:mmu:209003`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^1-50^E:5.9e-12",NA,NA,NA,NA,,
no,AD,MX,DN2895_c0_g1_i8,DN2895_c0_g1,RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",.,NA,GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",.,NA,NA,NA,NA,KEGG:mmu:209003`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,.,NA,NA,NA,NA,,
no,AD,MX,DN2895_c0_g1_i7,DN2895_c0_g1,RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",.,NA,GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",.,NA,NA,NA,NA,KEGG:mmu:209003`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,.,NA,NA,NA,NA,,
no,AD,MX,DN2895_c0_g1_i5,DN2895_c0_g1,RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",KEGG:mmu:209003`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,"PF13893.6^RRM_5^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^32-119^E:0.019",PF16367.5^RRM_7^RNA recognition motif^45-101^E:9.6e-07,"PF00076.22^RRM_1^RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)^48-118^E:1.7e-20",NA,NA,,
no,AD,MX,DN2895_c0_g1_i2,DN2895_c0_g1,RBMX2_MOUSE,"RNA-binding motif protein, X-linked 2",.,NA,GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",.,NA,NA,NA,NA,KEGG:mmu:209003`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,.,NA,NA,NA,NA,,
no,AD,MX,DN25295_c0_g1_i1,DN25295_c0_g1,LMX1A_HUMAN,LIM homeobox transcription factor 1-alpha,LMX1A_HUMAN,LIM homeobox transcription factor 1-alpha,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,KEGG:hsa:4009`KO:K09371,ENOG410YIJ3^sequence-specific DNA binding,PF00412.22^LIM^LIM domain^9-66^E:1.4e-16,PF00046.29^Homeodomain^Homeodomain^110-166^E:6.1e-18,PF05920.11^Homeobox_KN^Homeobox KN domain^134-162^E:0.00019,NA,NA,,
no,AD,MX,DN25295_c0_g1_i4,DN25295_c0_g1,LMX1A_HUMAN,LIM homeobox transcription factor 1-alpha,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:hsa:4009`KO:K09371,ENOG410YIJ3^sequence-specific DNA binding,.,NA,NA,NA,NA,,
no,AD,MX,DN3222_c0_g1_i2,DN3222_c0_g1,TMX4_MOUSE,Thioredoxin-related transmembrane protein 4,TMX4_HUMAN,Thioredoxin-related transmembrane protein 4,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,GO:0045454^biological_process^cell redox homeostasis,GO:0055114^biological_process^oxidation-reduction process,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,GO:0045454^biological_process^cell redox homeostasis,GO:0055114^biological_process^oxidation-reduction process,NA,KEGG:hsa:56255,ENOG4111H66^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN3222_c0_g1_i5,DN3222_c0_g1,TMX4_MOUSE,Thioredoxin-related transmembrane protein 4,TMX4_HUMAN,Thioredoxin-related transmembrane protein 4,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,GO:0045454^biological_process^cell redox homeostasis,GO:0055114^biological_process^oxidation-reduction process,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005637^cellular_component^nuclear inner membrane,GO:0045454^biological_process^cell redox homeostasis,GO:0055114^biological_process^oxidation-reduction process,NA,KEGG:hsa:56255,ENOG4111H66^thioredoxin-related transmembrane protein,PF00085.20^Thioredoxin^Thioredoxin^85-168^E:1.3e-16,NA,NA,NA,NA,,
no,AD,MX,DN9080_c1_g2_i2,DN9080_c1_g2,FUT4_BOVIN,"Alpha-(1,3)-fucosyltransferase 4",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:bta:282854`KO:K07632,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",.,NA,NA,NA,NA,,
no,AD,MX,DN11074_c0_g1_i1,DN11074_c0_g1,RBMX_RAT,"RNA-binding motif protein, X chromosome",.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0070062^cellular_component^extracellular exosome,GO:0005719^cellular_component^nuclear euchromatin,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,.,NA,NA,NA,NA,KEGG:rno:302855`KO:K12885,ENOG4111GI6^RNA binding motif protein,.,NA,NA,NA,NA,,
no,AD,MX,DN11094_c0_g1_i3,DN11094_c0_g1,.,NA,BRK1C_BOMMX,Kininogen-1c,.,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005179^molecular_function^hormone activity,GO:0090729^molecular_function^toxin activity,GO:0006952^biological_process^defense response,GO:0042311^biological_process^vasodilation,.,.,PF05001.13^RNA_pol_Rpb1_R^RNA polymerase Rpb1 C-terminal repeat^82-94^E:0.28,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i6,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,.,NA,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,.,NA,NA,NA,NA,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,.,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i5,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,.,NA,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,.,NA,NA,NA,NA,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,.,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i3,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,.,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i10,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^135-173^E:5.1e-20,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i12,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^135-173^E:5.2e-20,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i11,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^347-385^E:6.1e-20,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i8,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^347-385^E:6.2e-20,NA,NA,NA,NA,,
no,AD,MX,DN10252_c0_g1_i7,DN10252_c0_g1,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,BCL9_HUMAN,B-cell CLL/lymphoma 9 protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005801^cellular_component^cis-Golgi network,GO:0005654^cellular_component^nucleoplasm,GO:0008013^molecular_function^beta-catenin binding,GO:0003713^molecular_function^transcription coactivator activity,KEGG:hsa:607`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^352-390^E:6.2e-20,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i5,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^9-271^E:9.4e-67,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i13,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i6,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i12,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^9-353^E:4.2e-68,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i2,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^9-353^E:4e-68,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i8,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,"PF00400.32^WD40^WD domain, G-beta repeat^420-456^E:0.0017",NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i9,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i11,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i10,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i1,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i4,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,"PF00400.32^WD40^WD domain, G-beta repeat^669-705^E:0.0028",NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i19,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN10378_c0_g1_i14,DN10378_c0_g1,DMXL2_HUMAN,DmX-like protein 2,DMXL2_HUMAN,DmX-like protein 2,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,PF12234.8^Rav1p_C^RAVE protein 1 C terminal^9-353^E:4e-68,NA,NA,NA,NA,,
no,AD,MX,DN51023_c0_g1_i1,DN51023_c0_g1,TMX3_XENLA,Protein disulfide-isomerase TMX3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0045454^biological_process^cell redox homeostasis,NA,.,NA,NA,NA,NA,KEGG:xla:444355`KO:K09585,.,.,NA,NA,NA,NA,,
no,AD,MX,DN3563_c0_g1_i5,DN3563_c0_g1,MXRA8_CHICK,Matrix remodeling-associated protein 8,MXRA8_CHICK,Matrix remodeling-associated protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,KEGG:gga:395347,ENOG41113W9^matrix-remodelling associated 8,PF07686.17^V-set^Immunoglobulin V-set domain^41-157^E:1.3e-07,PF07686.17^V-set^Immunoglobulin V-set domain^175-292^E:9.7e-16,NA,NA,NA,,
Yes,,MX,DN3563_c0_g1_i2,DN3563_c0_g1,MXRA8_CHICK,Matrix remodeling-associated protein 8,MXRA8_CHICK,Matrix remodeling-associated protein 8,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0007155^biological_process^cell adhesion,NA,NA,KEGG:gga:395347,ENOG41113W9^matrix-remodelling associated 8,PF07686.17^V-set^Immunoglobulin V-set domain^41-157^E:1.3e-07,PF07686.17^V-set^Immunoglobulin V-set domain^175-292^E:9.7e-16,NA,NA,NA,,
Yes,,MX,DN5715_c0_g1_i5,DN5715_c0_g1,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,KEGG:hsa:25878,COG4886^leucine Rich Repeat,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^126-240^E:7.4e-06,PF13855.6^LRR_8^Leucine rich repeat^148-207^E:1.2e-11,PF13855.6^LRR_8^Leucine rich repeat^195-251^E:7.8e-10,PF13855.6^LRR_8^Leucine rich repeat^248-286^E:5.7e-08,PF13927.6^Ig_3^Immunoglobulin domain^548-619^E:3.7e-09,,
Yes,,MX,DN5715_c0_g1_i6,DN5715_c0_g1,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,KEGG:hsa:25878,COG4886^leucine Rich Repeat,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^126-240^E:7.4e-06,PF13855.6^LRR_8^Leucine rich repeat^148-207^E:1.2e-11,PF13855.6^LRR_8^Leucine rich repeat^195-251^E:7.8e-10,PF13855.6^LRR_8^Leucine rich repeat^248-286^E:5.7e-08,PF13927.6^Ig_3^Immunoglobulin domain^548-619^E:3.7e-09,,
Yes,,MX,DN5715_c0_g1_i1,DN5715_c0_g1,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,MXRA5_HUMAN,Matrix-remodeling-associated protein 5,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,GO:0062023^cellular_component^collagen-containing extracellular matrix,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005201^molecular_function^extracellular matrix structural constituent,GO:0071559^biological_process^response to transforming growth factor beta,KEGG:hsa:25878,COG4886^leucine Rich Repeat,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^126-240^E:7.4e-06,PF13855.6^LRR_8^Leucine rich repeat^148-207^E:1.2e-11,PF13855.6^LRR_8^Leucine rich repeat^195-251^E:7.8e-10,PF13855.6^LRR_8^Leucine rich repeat^248-286^E:5.7e-08,PF13927.6^Ig_3^Immunoglobulin domain^548-619^E:3.7e-09,,
no,AD,MX,DN45019_c0_g1_i3,DN45019_c0_g1,BMX_MOUSE,Cytoplasmic tyrosine-protein kinase BMX,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:12169`KO:K08896,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,AD,MX,DN34462_c0_g1_i2,DN34462_c0_g1,PRP2_SOYBN,Repetitive proline-rich cell wall protein 2,.,NA,GO:0005618^cellular_component^cell wall,GO:0005576^cellular_component^extracellular region,GO:0005199^molecular_function^structural constituent of cell wall,GO:0007275^biological_process^multicellular organism development,NA,.,NA,NA,NA,NA,KEGG:gmx:547830,.,.,NA,NA,NA,NA,,
no,AD,MX,DN34451_c1_g1_i2,DN34451_c1_g1,CPLX2_RAT,Complexin-2,CPLX2_RAT,Complexin-2,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:116657`KO:K15294,ENOG4111MX0^Complexin,PF05835.12^Synaphin^Synaphin protein^13-133^E:2.5e-33,NA,NA,NA,NA,,
no,AD,MX,DN34451_c1_g1_i1,DN34451_c1_g1,CPLX2_RAT,Complexin-2,CPLX2_RAT,Complexin-2,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,KEGG:rno:116657`KO:K15294,ENOG4111MX0^Complexin,PF05835.12^Synaphin^Synaphin protein^13-72^E:4.6e-17,NA,NA,NA,NA,,
no,AD,MX,DN34451_c1_g2_i1,DN34451_c1_g2,CPLX2_RAT,Complexin-2,.,NA,GO:0044305^cellular_component^calyx of Held,GO:0030054^cellular_component^cell junction,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0098978^cellular_component^glutamatergic synapse,.,NA,NA,NA,NA,KEGG:rno:116657`KO:K15294,ENOG4111MX0^Complexin,.,NA,NA,NA,NA,,
no,AD,MX,DN2466_c0_g1_i1,DN2466_c0_g1,RBMX_PANTR,"RNA-binding motif protein, X chromosome",RBMX_RAT,"RNA-binding motif protein, X chromosome",GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0070062^cellular_component^extracellular exosome,GO:0005719^cellular_component^nuclear euchromatin,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0070062^cellular_component^extracellular exosome,GO:0005719^cellular_component^nuclear euchromatin,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,KEGG:rno:302855`KO:K12885,ENOG4111GI6^RNA binding motif protein,PF08081.11^RBM1CTR^RBM1CTR (NUC064) family^89-133^E:2.5e-21,NA,NA,NA,NA,,
no,AD,MX,DN2466_c0_g1_i4,DN2466_c0_g1,RBMX_RAT,"RNA-binding motif protein, X chromosome",.,NA,GO:0071013^cellular_component^catalytic step 2 spliceosome,GO:0070062^cellular_component^extracellular exosome,GO:0005719^cellular_component^nuclear euchromatin,GO:0005634^cellular_component^nucleus,GO:1990904^cellular_component^ribonucleoprotein complex,.,NA,NA,NA,NA,KEGG:rno:302855`KO:K12885,ENOG4111GI6^RNA binding motif protein,.,NA,NA,NA,NA,,
no,AD,MX,DN2420_c2_g1_i3,DN2420_c2_g1,BCL9L_MOUSE,B-cell CLL/lymphoma 9-like protein,BCL9L_MOUSE,B-cell CLL/lymphoma 9-like protein,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008013^molecular_function^beta-catenin binding,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008013^molecular_function^beta-catenin binding,KEGG:mmu:80288`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,PF11502.8^BCL9^B-cell lymphoma 9 protein^467-504^E:8e-16,NA,NA,NA,NA,,
no,AD,MX,DN37540_c0_g1_i1,DN37540_c0_g1,BCL9L_HUMAN,B-cell CLL/lymphoma 9-like protein,.,NA,GO:1990907^cellular_component^beta-catenin-TCF complex,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0008013^molecular_function^beta-catenin binding,.,NA,NA,NA,NA,KEGG:hsa:283149`KO:K22649,ENOG410XRMX^B-cell CLL lymphoma,.,NA,NA,NA,NA,,
no,AD,MX,DN6482_c1_g1_i2,DN6482_c1_g1,TMX3_HUMAN,Protein disulfide-isomerase TMX3,.,NA,GO:0009986^cellular_component^cell surface,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0031092^cellular_component^platelet alpha granule membrane,.,NA,NA,NA,NA,KEGG:hsa:54495`KO:K09585,COG0526^Thioredoxin,.,NA,NA,NA,NA,,
no,AD,MX,DN1894_c0_g1_i3,DN1894_c0_g1,TMX1_HUMAN,Thioredoxin-related transmembrane protein 1,TMX1_HUMAN,Thioredoxin-related transmembrane protein 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015036^molecular_function^disulfide oxidoreductase activity,GO:0045454^biological_process^cell redox homeostasis,GO:0034976^biological_process^response to endoplasmic reticulum stress,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015036^molecular_function^disulfide oxidoreductase activity,GO:0045454^biological_process^cell redox homeostasis,GO:0034976^biological_process^response to endoplasmic reticulum stress,KEGG:hsa:81542,ENOG4111H66^thioredoxin-related transmembrane protein,PF00085.20^Thioredoxin^Thioredoxin^42-136^E:3.5e-21,NA,NA,NA,NA,,
no,AD,MX,DN1894_c0_g1_i6,DN1894_c0_g1,TMX1_HUMAN,Thioredoxin-related transmembrane protein 1,TMX1_BOVIN,Thioredoxin-related transmembrane protein 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015036^molecular_function^disulfide oxidoreductase activity,GO:0045454^biological_process^cell redox homeostasis,GO:0034976^biological_process^response to endoplasmic reticulum stress,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015036^molecular_function^disulfide oxidoreductase activity,GO:0045454^biological_process^cell redox homeostasis,GO:0034976^biological_process^response to endoplasmic reticulum stress,KEGG:bta:509037,ENOG4111H66^thioredoxin-related transmembrane protein,PF00085.20^Thioredoxin^Thioredoxin^42-136^E:8.2e-22,NA,NA,NA,NA,,
no,AD,MX,DN9842_c0_g1_i1,DN9842_c0_g1,FUT7_MOUSE,"Alpha-(1,3)-fucosyltransferase 7",.,NA,GO:0005794^cellular_component^Golgi apparatus,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0008417^molecular_function^fucosyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:14347`KO:K07635,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",.,NA,NA,NA,NA,,
no,AD,MX,DN18284_c0_g1_i2,DN18284_c0_g1,TMX3_PONAB,Protein disulfide-isomerase TMX3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003756^molecular_function^protein disulfide isomerase activity,GO:0045454^biological_process^cell redox homeostasis,NA,.,NA,NA,NA,NA,KEGG:pon:100173147`KO:K09585,COG0526^Thioredoxin,.,NA,NA,NA,NA,,
no,AD,MX,DN1669_c1_g1_i4,DN1669_c1_g1,FUT10_CHICK,"Alpha-(1,3)-fucosyltransferase 10",FUT10_CHICK,"Alpha-(1,3)-fucosyltransferase 10",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,.,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase",PF00852.19^Glyco_transf_10^Glycosyltransferase family 10 (fucosyltransferase) C-term^18-201^E:1.1e-37,NA,NA,NA,NA,,
no,AD,MX,DN1669_c1_g1_i9,DN1669_c1_g1,FUT10_CHICK,"Alpha-(1,3)-fucosyltransferase 10",FUT10_CHICK,"Alpha-(1,3)-fucosyltransferase 10",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,.,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase","PF17039.5^Glyco_tran_10_N^Fucosyltransferase, N-terminal^78-176^E:1.2e-10",PF00852.19^Glyco_transf_10^Glycosyltransferase family 10 (fucosyltransferase) C-term^211-394^E:4.1e-37,NA,NA,NA,,
no,AD,MX,DN31298_c0_g1_i2,DN31298_c0_g1,BMX_HUMAN,Cytoplasmic tyrosine-protein kinase BMX,.,NA,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005886^cellular_component^plasma membrane,GO:0032587^cellular_component^ruffle membrane,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:660`KO:K08896,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
no,AD,MX,DN126473_c0_g1_i1,DN126473_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN113028_c0_g1_i1,DN113028_c0_g1,TMX2_HUMAN,Thioredoxin-related transmembrane protein 2,TMX2_HUMAN,Thioredoxin-related transmembrane protein 2,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,KEGG:hsa:51075,ENOG410XVTA^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN116575_c0_g1_i1,DN116575_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,.,NA,NA,NA,NA,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN151679_c0_g1_i1,DN151679_c0_g1,.,NA,AGLZ_MYXXD,Adventurous-gliding motility protein Z,.,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0000160^biological_process^phosphorelay signal transduction system,NA,NA,NA,KEGG:mxa:MXAN_2991,ENOG41122PT^NA,.,NA,NA,NA,NA,,
no,AD,MX,DN109385_c0_g1_i1,DN109385_c0_g1,RBMX2_HUMAN,"RNA-binding motif protein, X-linked 2",.,NA,GO:0005634^cellular_component^nucleus,GO:0005686^cellular_component^U2 snRNP,GO:0071005^cellular_component^U2-type precatalytic spliceosome,GO:0003723^molecular_function^RNA binding,"GO:0000398^biological_process^mRNA splicing, via spliceosome",.,NA,NA,NA,NA,KEGG:hsa:51634`KO:K13107,ENOG4111KW0^RNA binding motif protein X-linked 2,.,NA,NA,NA,NA,,
no,AD,MX,DN183753_c0_g1_i1,DN183753_c0_g1,NMS_BOMOR,Neuromedin-S,NMS_BOMMX,Neuromedin-S,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,.,.,PF02070.15^NMU^Neuromedin U^92-101^E:0.0045,NA,NA,NA,NA,,
no,AD,MX,DN183786_c0_g1_i1,DN183786_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN123882_c0_g1_i1,DN123882_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",.,NA,NA,NA,NA,KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN134061_c0_g1_i1,DN134061_c0_g1,DEN4C_HUMAN,DENN domain-containing protein 4C,.,NA,GO:0030659^cellular_component^cytoplasmic vesicle membrane,GO:0005829^cellular_component^cytosol,GO:0032593^cellular_component^insulin-responsive compartment,GO:0005886^cellular_component^plasma membrane,GO:0030904^cellular_component^retromer complex,.,NA,NA,NA,NA,KEGG:hsa:55667`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN155739_c0_g1_i1,DN155739_c0_g1,DMXL2_HUMAN,DmX-like protein 2,.,NA,GO:0030054^cellular_component^cell junction,GO:0005615^cellular_component^extracellular space,GO:0043291^cellular_component^RAVE complex,GO:0008021^cellular_component^synaptic vesicle,GO:0030672^cellular_component^synaptic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:23312,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN278133_c0_g1_i1,DN278133_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN274516_c0_g1_i1,DN274516_c0_g1,EMX2_HUMAN,Homeobox protein EMX2,.,NA,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0001162^molecular_function^RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding,.,NA,NA,NA,NA,KEGG:hsa:2018`KO:K09317,ENOG4111SRW^homeobox,.,NA,NA,NA,NA,,
no,AD,MX,DN209737_c0_g1_i1,DN209737_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN250109_c0_g1_i1,DN250109_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN288571_c0_g1_i1,DN288571_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,PF11971.8^CAMSAP_CH^CAMSAP CH domain^94-133^E:0.00024,NA,NA,NA,NA,,
no,AD,MX,DN248208_c0_g1_i1,DN248208_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN210215_c0_g1_i1,DN210215_c0_g1,MYCPP_HUMAN,C-myc promoter-binding protein,.,NA,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0017112^molecular_function^Rab guanyl-nucleotide exchange factor activity,"GO:0006355^biological_process^regulation of transcription, DNA-templated",.,NA,NA,NA,NA,KEGG:hsa:10260`KO:K20163,ENOG410XQMX^DENN MADD domain containing,.,NA,NA,NA,NA,,
no,AD,MX,DN345347_c0_g1_i1,DN345347_c0_g1,LMX1A_MESAU,LIM homeobox transcription factor 1-alpha,LMX1A_MESAU,LIM homeobox transcription factor 1-alpha,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0007411^biological_process^axon guidance,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0046872^molecular_function^metal ion binding,GO:0000977^molecular_function^RNA polymerase II regulatory region sequence-specific DNA binding,GO:0007411^biological_process^axon guidance,.,.,PF00412.22^LIM^LIM domain^49-100^E:1.8e-14,NA,NA,NA,NA,,
no,AD,MX,DN345415_c0_g1_i1,DN345415_c0_g1,EMX2_MOUSE,Homeobox protein EMX2,EMX2_MOUSE,Homeobox protein EMX2,GO:0005634^cellular_component^nucleus,"GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0001162^molecular_function^RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0009952^biological_process^anterior/posterior pattern specification,GO:0005634^cellular_component^nucleus,"GO:0001227^molecular_function^DNA-binding transcription repressor activity, RNA polymerase II-specific",GO:0001162^molecular_function^RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding,GO:0000978^molecular_function^RNA polymerase II proximal promoter sequence-specific DNA binding,GO:0009952^biological_process^anterior/posterior pattern specification,KEGG:mmu:13797`KO:K09317,ENOG4111SRW^homeobox,PF00046.29^Homeodomain^Homeodomain^55-111^E:5.7e-22,NA,NA,NA,NA,,
no,AD,MX,DN307497_c0_g1_i1,DN307497_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN395758_c0_g1_i1,DN395758_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN356263_c0_g1_i1,DN356263_c0_g1,DMXL1_HUMAN,DmX-like protein 1,.,NA,GO:0043291^cellular_component^RAVE complex,GO:0007035^biological_process^vacuolar acidification,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:1657,ENOG410XPUM^Dmx-like 1,.,NA,NA,NA,NA,,
no,AD,MX,DN416369_c0_g1_i1,DN416369_c0_g1,FUT9_CANLF,"Alpha-(1,3)-fucosyltransferase 9",FUT9_CANLF,"Alpha-(1,3)-fucosyltransferase 9",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046920^molecular_function^alpha-(1->3)-fucosyltransferase activity,GO:0036065^biological_process^fucosylation,GO:0006486^biological_process^protein glycosylation,KEGG:cfa:449027`KO:K03663,"ENOG410ZIMX^(Alpha (1,3) fucosyltransferase","PF17039.5^Glyco_tran_10_N^Fucosyltransferase, N-terminal^55-162^E:2.6e-40",NA,NA,NA,NA,,
no,AD,MX,DN435545_c0_g1_i1,DN435545_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN408537_c0_g1_i1,DN408537_c0_g1,TMX2_RAT,Thioredoxin-related transmembrane protein 2,.,NA,GO:0005623^cellular_component^cell,GO:0016021^cellular_component^integral component of membrane,GO:0045454^biological_process^cell redox homeostasis,NA,NA,.,NA,NA,NA,NA,KEGG:rno:295701,ENOG410XVTA^thioredoxin-related transmembrane protein,.,NA,NA,NA,NA,,
no,AD,MX,DN447377_c0_g1_i1,DN447377_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
no,AD,MX,DN458197_c0_g1_i1,DN458197_c0_g1,CFA47_HUMAN,Cilia- and flagella-associated protein 47 {ECO:0000305},.,NA,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:286464,ENOG410ZNN9^chromosome X open reading frame 22`ENOG410ZSPY^chromosome X open reading frame 59`ENOG410ZVMX^chromosome X open reading frame 30,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN2043_c0_g1_i3,DN2043_c0_g1,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:gga:420032`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^6-110^E:1.6e-11,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^6-111^E:2.8e-07",PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^6-97^E:0.00015,NA,NA,,
yes,AD,NF-kappa-B,DN2043_c0_g1_i5,DN2043_c0_g1,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:gga:420032`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00025.21^Arf^ADP-ribosylation factor family^3-132^E:1.5e-07,PF00071.22^Ras^Ras family^6-169^E:3.9e-25,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^6-124^E:2.1e-10",PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^6-116^E:4.8e-05,NA,,
yes,AD,NF-kappa-B,DN2043_c0_g1_i7,DN2043_c0_g1,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,KBRS2_CHICK,NF-kappa-B inhibitor-interacting Ras-like protein 2,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:gga:420032`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00025.21^Arf^ADP-ribosylation factor family^3-132^E:1.5e-07,PF00071.22^Ras^Ras family^6-169^E:3.9e-25,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^6-124^E:2.1e-10",PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^6-116^E:4.8e-05,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i7,DN825_c0_g1,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,.,NA,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,.,NA,NA,NA,NA,KEGG:hsa:64332`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i10,DN825_c0_g1,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:hsa:64332`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i8,DN825_c0_g1,IKBZ_BOVIN,NF-kappa-B inhibitor zeta,.,NA,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,.,NA,NA,NA,NA,KEGG:bta:282713`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i2,DN825_c0_g1,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:hsa:64332`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i11,DN825_c0_g1,IKBZ_BOVIN,NF-kappa-B inhibitor zeta,IKBZ_BOVIN,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:bta:282713`KO:K14242,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^1-58^E:0.024,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^38-132^E:1.9e-13,PF00023.30^Ank^Ankyrin repeat^62-82^E:0.023,PF00023.30^Ank^Ankyrin repeat^97-132^E:4.8e-05,NA,,
yes,AD,NF-kappa-B,DN825_c0_g1_i12,DN825_c0_g1,IKBZ_HUMAN,NF-kappa-B inhibitor zeta,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:mmu:80859`KO:K14242,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^40-75^E:1.9e-05,PF13606.6^Ank_3^Ankyrin repeat^40-72^E:0.0044,NA,NA,NA,,
yes,AD,NF-kappa-B,DN78251_c0_g1_i1,DN78251_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN5474_c0_g1_i7,DN5474_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,PF16179.5^RHD_dimer^Rel homology dimerisation domain^1-75^E:2.1e-25,PF13857.6^Ank_5^Ankyrin repeats (many copies)^293-340^E:5.5e-07,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^301-355^E:1.7e-06,PF00023.30^Ank^Ankyrin repeat^302-330^E:0.00012,PF00023.30^Ank^Ankyrin repeat^332-355^E:0.0055,,
yes,AD,NF-kappa-B,DN5474_c0_g1_i1,DN5474_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN5474_c0_g1_i4,DN5474_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,PF16179.5^RHD_dimer^Rel homology dimerisation domain^1-60^E:1.3e-19,PF13857.6^Ank_5^Ankyrin repeats (many copies)^278-325^E:5.3e-07,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^285-340^E:1.7e-06,PF00023.30^Ank^Ankyrin repeat^287-315^E:0.00012,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^289-382^E:7.8e-09,,
yes,AD,NF-kappa-B,DN5474_c0_g1_i5,DN5474_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,PF00554.22^RHD_DNA_bind^Rel homology DNA-binding domain^49-247^E:1.1e-70,PF16179.5^RHD_dimer^Rel homology dimerisation domain^256-357^E:6.5e-40,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^525-610^E:8.8e-08,PF13857.6^Ank_5^Ankyrin repeats (many copies)^575-622^E:8.4e-07,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^582-637^E:2.5e-06,,
yes,AD,NF-kappa-B,DN5474_c0_g1_i6,DN5474_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,PF00531.22^Death^Death domain^1-75^E:5.2e-10,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN5474_c0_g2_i1,DN5474_c0_g2,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN4512_c1_g1_i12,DN4512_c1_g1,CD14_BOVIN,Monocyte differentiation antigen CD14,TLR2_GIRCA,Toll-like receptor 2,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0071726^biological_process^cellular response to diacyl bacterial lipopeptide,KEGG:bta:281048`KO:K04391,"ENOG41118N2^In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity)",PF13516.6^LRR_6^Leucine Rich repeat^164-176^E:3400,PF00560.33^LRR_1^Leucine Rich Repeat^165-176^E:17000,PF00560.33^LRR_1^Leucine Rich Repeat^189-206^E:38,PF13516.6^LRR_6^Leucine Rich repeat^189-205^E:14,PF13516.6^LRR_6^Leucine Rich repeat^216-226^E:1400,,
yes,AD,NF-kappa-B,DN4512_c1_g1_i4,DN4512_c1_g1,CD14_BOVIN,Monocyte differentiation antigen CD14,TLR2_GIRCA,Toll-like receptor 2,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0071726^biological_process^cellular response to diacyl bacterial lipopeptide,KEGG:bta:281048`KO:K04391,"ENOG41118N2^In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity)",PF13516.6^LRR_6^Leucine Rich repeat^164-176^E:3400,PF00560.33^LRR_1^Leucine Rich Repeat^165-176^E:17000,PF00560.33^LRR_1^Leucine Rich Repeat^189-206^E:38,PF13516.6^LRR_6^Leucine Rich repeat^189-205^E:14,PF13516.6^LRR_6^Leucine Rich repeat^216-226^E:1400,,
yes,AD,NF-kappa-B,DN4512_c1_g1_i7,DN4512_c1_g1,CD14_BOVIN,Monocyte differentiation antigen CD14,.,NA,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:bta:281048`KO:K04391,"ENOG41118N2^In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity)",.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN4512_c1_g1_i2,DN4512_c1_g1,CD14_BOVIN,Monocyte differentiation antigen CD14,.,NA,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:bta:281048`KO:K04391,"ENOG41118N2^In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity)",.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN4512_c1_g1_i6,DN4512_c1_g1,CD14_BOVIN,Monocyte differentiation antigen CD14,TLR2_GIRCA,Toll-like receptor 2,GO:0031362^cellular_component^anchored component of external side of plasma membrane,GO:0009986^cellular_component^cell surface,GO:0009897^cellular_component^external side of plasma membrane,GO:0005576^cellular_component^extracellular region,GO:0005794^cellular_component^Golgi apparatus,GO:0005794^cellular_component^Golgi apparatus,GO:0016021^cellular_component^integral component of membrane,GO:0045121^cellular_component^membrane raft,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0071726^biological_process^cellular response to diacyl bacterial lipopeptide,KEGG:bta:281048`KO:K04391,"ENOG41118N2^In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2 TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity)",PF13516.6^LRR_6^Leucine Rich repeat^164-176^E:3400,PF00560.33^LRR_1^Leucine Rich Repeat^165-176^E:17000,PF00560.33^LRR_1^Leucine Rich Repeat^189-206^E:38,PF13516.6^LRR_6^Leucine Rich repeat^189-205^E:14,PF13516.6^LRR_6^Leucine Rich repeat^216-226^E:1400,,
yes,AD,NF-kappa-B,DN3184_c1_g1_i15,DN3184_c1_g1,NEMO_MOUSE,NF-kappa-B essential modulator,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:16151`KO:K07210,"ENOG410Y1FG^Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma",.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN3184_c1_g1_i13,DN3184_c1_g1,NEMO_MOUSE,NF-kappa-B essential modulator,NEMO_BOVIN,NF-kappa-B essential modulator,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,KEGG:bta:281855`KO:K07210,"ENOG410Y1FG^Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","PF16516.5^CC2-LZ^Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator^263-349^E:3.3e-26",PF18414.1^zf_C2H2_10^C2H2 type zinc-finger^391-416^E:7.9e-16,NA,NA,NA,,
yes,AD,NF-kappa-B,DN3184_c1_g1_i10,DN3184_c1_g1,NEMO_MOUSE,NF-kappa-B essential modulator,NEMO_BOVIN,NF-kappa-B essential modulator,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,KEGG:bta:281855`KO:K07210,"ENOG410Y1FG^Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","PF16516.5^CC2-LZ^Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator^263-349^E:3.3e-26",PF18414.1^zf_C2H2_10^C2H2 type zinc-finger^391-416^E:7.9e-16,NA,NA,NA,,
yes,AD,NF-kappa-B,DN3184_c1_g1_i19,DN3184_c1_g1,NEMO_BOVIN,NF-kappa-B essential modulator,NEMO_BOVIN,NF-kappa-B essential modulator,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,KEGG:bta:281855`KO:K07210,"ENOG410Y1FG^Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma",PF11577.8^NEMO^NF-kappa-B essential modulator NEMO^2-64^E:1.1e-10,"PF16516.5^CC2-LZ^Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator^284-370^E:3.3e-26",NA,NA,NA,,
yes,AD,NF-kappa-B,DN3184_c1_g1_i18,DN3184_c1_g1,NEMO_BOVIN,NF-kappa-B essential modulator,NEMO_BOVIN,NF-kappa-B essential modulator,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,GO:0005737^cellular_component^cytoplasm,GO:0008385^cellular_component^IkappaB kinase complex,GO:0072686^cellular_component^mitotic spindle,GO:0005634^cellular_component^nucleus,GO:0000922^cellular_component^spindle pole,KEGG:bta:281855`KO:K07210,"ENOG410Y1FG^Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","PF16516.5^CC2-LZ^Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator^292-378^E:3.4e-26",NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN7919_c0_g1_i8,DN7919_c0_g1,IKBE_MOUSE,NF-kappa-B inhibitor epsilon,.,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005794^cellular_component^Golgi apparatus,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,.,NA,NA,NA,NA,KEGG:mmu:18037`KO:K05872,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN7919_c0_g1_i9,DN7919_c0_g1,IKBE_MOUSE,NF-kappa-B inhibitor epsilon,IKBE_MOUSE,NF-kappa-B inhibitor epsilon,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005794^cellular_component^Golgi apparatus,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005794^cellular_component^Golgi apparatus,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:mmu:18037`KO:K05872,COG0666^Ankyrin Repeat,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^143-203^E:1.8e-08,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^149-247^E:4.2e-12,PF00023.30^Ank^Ankyrin repeat^177-204^E:0.0013,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^215-280^E:1.8e-09,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^222-313^E:1e-13,,
yes,AD,NF-kappa-B,DN7919_c0_g1_i7,DN7919_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,PF00554.22^RHD_DNA_bind^Rel homology DNA-binding domain^50-229^E:4.2e-65,PF16179.5^RHD_dimer^Rel homology dimerisation domain^238-336^E:5.2e-38,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^481-553^E:6.7e-10,PF13857.6^Ank_5^Ankyrin repeats (many copies)^518-565^E:3.8e-07,PF00023.30^Ank^Ankyrin repeat^526-555^E:3.6e-05,,
yes,AD,NF-kappa-B,DN7919_c0_g1_i4,DN7919_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,PF00554.22^RHD_DNA_bind^Rel homology DNA-binding domain^111-290^E:4.7e-65,PF16179.5^RHD_dimer^Rel homology dimerisation domain^299-397^E:5.7e-38,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^542-614^E:6.4e-10,PF13857.6^Ank_5^Ankyrin repeats (many copies)^579-626^E:4.1e-07,PF00023.30^Ank^Ankyrin repeat^587-616^E:3.9e-05,,
yes,AD,NF-kappa-B,DN8041_c0_g1_i1,DN8041_c0_g1,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:mmu:80859`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8041_c0_g1_i5,DN8041_c0_g1,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,IKBZ_BOVIN,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:bta:282713`KO:K14242,COG0666^Ankyrin Repeat,PF13606.6^Ank_3^Ankyrin repeat^15-41^E:0.0028,PF13637.6^Ank_4^Ankyrin repeats (many copies)^16-66^E:1.1e-09,PF00023.30^Ank^Ankyrin repeat^16-44^E:3.4e-05,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^18-94^E:5.7e-10,PF00023.30^Ank^Ankyrin repeat^47-67^E:0.011,,
yes,AD,NF-kappa-B,DN8041_c0_g1_i3,DN8041_c0_g1,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:mmu:80859`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8041_c0_g1_i9,DN8041_c0_g1,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,IKBZ_MOUSE,NF-kappa-B inhibitor zeta,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,KEGG:mmu:80859`KO:K14242,COG0666^Ankyrin Repeat,PF13606.6^Ank_3^Ankyrin repeat^148-175^E:0.0033,PF13637.6^Ank_4^Ankyrin repeats (many copies)^149-200^E:7.6e-10,PF00023.30^Ank^Ankyrin repeat^149-178^E:4.6e-05,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^167-228^E:6.5e-07,PF00023.30^Ank^Ankyrin repeat^181-201^E:0.023,,
yes,AD,NF-kappa-B,DN8041_c0_g1_i6,DN8041_c0_g1,IKBZ_BOVIN,NF-kappa-B inhibitor zeta,.,NA,GO:0036464^cellular_component^cytoplasmic ribonucleoprotein granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0006954^biological_process^inflammatory response,GO:0050729^biological_process^positive regulation of inflammatory response,.,NA,NA,NA,NA,KEGG:bta:282713`KO:K14242,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8032_c1_g2_i1,DN8032_c1_g2,NKRF_HUMAN,NF-kappa-B-repressing factor,NKRF_HUMAN,NF-kappa-B-repressing factor,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003723^molecular_function^RNA binding,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0003723^molecular_function^RNA binding,KEGG:hsa:55922,COG5048^Zinc finger protein,"PF11952.8^XTBD^XRN-Two Binding Domain, XTBD^72-147^E:1.1e-25",PF01585.23^G-patch^G-patch domain^687-728^E:7.1e-13,PF12656.7^G-patch_2^G-patch domain^687-730^E:0.00011,PF01424.22^R3H^R3H domain^740-797^E:2.6e-13,NA,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i3,DN8072_c0_g1,OBF1_BOVIN,POU domain class 2-associating factor 1,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^6-62^E:0.0004,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^46-137^E:4.9e-12,PF00023.30^Ank^Ankyrin repeat^102-137^E:1.2e-08,PF13606.6^Ank_3^Ankyrin repeat^102-134^E:0.00027,PF13637.6^Ank_4^Ankyrin repeats (many copies)^104-147^E:6.7e-06,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i15,DN8072_c0_g1,OBF1_BOVIN,POU domain class 2-associating factor 1,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^6-62^E:0.0004,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^46-137^E:4.9e-12,PF00023.30^Ank^Ankyrin repeat^102-137^E:1.2e-08,PF13606.6^Ank_3^Ankyrin repeat^102-134^E:0.00027,PF13637.6^Ank_4^Ankyrin repeats (many copies)^104-147^E:6.7e-06,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i14,DN8072_c0_g1,OBF1_BOVIN,POU domain class 2-associating factor 1,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^6-62^E:0.0004,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^46-137^E:4.9e-12,PF00023.30^Ank^Ankyrin repeat^102-137^E:1.2e-08,PF13606.6^Ank_3^Ankyrin repeat^102-134^E:0.00027,PF13637.6^Ank_4^Ankyrin repeats (many copies)^104-147^E:6.7e-06,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i6,DN8072_c0_g1,IKBD_HUMAN,NF-kappa-B inhibitor delta,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^71-102^E:0.0036,PF13857.6^Ank_5^Ankyrin repeats (many copies)^90-144^E:1.5e-10,PF00023.30^Ank^Ankyrin repeat^104-125^E:0.011,PF00023.30^Ank^Ankyrin repeat^139-195^E:0.0011,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^179-270^E:1.8e-11,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i10,DN8072_c0_g1,IKBD_HUMAN,NF-kappa-B inhibitor delta,.,NA,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,.,NA,NA,NA,NA,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i7,DN8072_c0_g1,OBF1_BOVIN,POU domain class 2-associating factor 1,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^6-62^E:0.0004,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^46-137^E:4.9e-12,PF00023.30^Ank^Ankyrin repeat^102-137^E:1.2e-08,PF13606.6^Ank_3^Ankyrin repeat^102-134^E:0.00027,PF13637.6^Ank_4^Ankyrin repeats (many copies)^104-147^E:6.7e-06,,
yes,AD,NF-kappa-B,DN8072_c0_g1_i13,DN8072_c0_g1,IKBD_HUMAN,NF-kappa-B inhibitor delta,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^18-74^E:0.00046,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^58-149^E:5.8e-12,PF00023.30^Ank^Ankyrin repeat^114-149^E:1.4e-08,PF13606.6^Ank_3^Ankyrin repeat^114-146^E:0.00031,PF13637.6^Ank_4^Ankyrin repeats (many copies)^116-159^E:7.3e-06,,
yes,AD,NF-kappa-B,DN40287_c0_g1_i2,DN40287_c0_g1,NFKB2_HUMAN,Nuclear factor NF-kappa-B p100 subunit,.,NA,GO:0033257^cellular_component^Bcl3/NF-kappaB2 complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:4791`KO:K04469,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN40287_c0_g1_i4,DN40287_c0_g1,NFKB1_HUMAN,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005576^cellular_component^extracellular region,GO:0033256^cellular_component^I-kappaB/NF-kappaB complex,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:4790`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i2,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i6,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,PF12845.7^TBD^TBD domain^190-245^E:4.1e-27,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i7,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,PF12845.7^TBD^TBD domain^190-245^E:4.1e-27,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i4,DN8303_c0_g1,TANK_HUMAN,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0031625^molecular_function^ubiquitin protein ligase binding,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i3,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,PF12845.7^TBD^TBD domain^190-245^E:3.7e-27,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i1,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,.,NA,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,.,NA,NA,NA,NA,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN8303_c0_g1_i5,DN8303_c0_g1,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,TANK_MOUSE,TRAF family member-associated NF-kappa-B activator,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,GO:0005829^cellular_component^cytosol,GO:0032991^cellular_component^protein-containing complex,GO:0035800^molecular_function^deubiquitinase activator activity,GO:0046872^molecular_function^metal ion binding,GO:0004843^molecular_function^thiol-dependent ubiquitin-specific protease activity,KEGG:mmu:21353`KO:K12650,ENOG410Y7D3^TRAF family member-associated NFKB activator,PF12845.7^TBD^TBD domain^168-223^E:3.8e-27,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN27902_c0_g1_i2,DN27902_c0_g1,IKBA_CHICK,NF-kappa-B inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,.,NA,NA,NA,NA,.,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN27902_c0_g1_i4,DN27902_c0_g1,IKBA_CHICK,NF-kappa-B inhibitor alpha,IKBA_CHICK,NF-kappa-B inhibitor alpha,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,.,COG0666^Ankyrin Repeat,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^186-254^E:3.8e-06,PF13857.6^Ank_5^Ankyrin repeats (many copies)^220-264^E:2.3e-10,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^223-279^E:6e-09,PF13606.6^Ank_3^Ankyrin repeat^225-252^E:0.0042,PF00023.30^Ank^Ankyrin repeat^226-254^E:0.00053,,
yes,AD,NF-kappa-B,DN27902_c0_g1_i1,DN27902_c0_g1,IKBA_CHICK,NF-kappa-B inhibitor alpha,IKBA_CHICK,NF-kappa-B inhibitor alpha,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,.,COG0666^Ankyrin Repeat,PF13857.6^Ank_5^Ankyrin repeats (many copies)^220-264^E:3.5e-10,PF00023.30^Ank^Ankyrin repeat^226-254^E:0.00078,PF13637.6^Ank_4^Ankyrin repeats (many copies)^226-276^E:5.5e-06,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^247-325^E:2.1e-13,PF00023.30^Ank^Ankyrin repeat^257-276^E:0.0031,,
yes,AD,NF-kappa-B,DN27902_c0_g1_i3,DN27902_c0_g1,IKBA_CHICK,NF-kappa-B inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,.,NA,NA,NA,NA,.,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN27902_c0_g1_i5,DN27902_c0_g1,IKBA_CHICK,NF-kappa-B inhibitor alpha,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0048145^biological_process^regulation of fibroblast proliferation,NA,NA,NA,.,NA,NA,NA,NA,.,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN2830_c2_g1_i5,DN2830_c2_g1,IKBB_MOUSE,NF-kappa-B inhibitor beta,IKBB_MOUSE,NF-kappa-B inhibitor beta,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007253^biological_process^cytoplasmic sequestering of NF-kappaB,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007253^biological_process^cytoplasmic sequestering of NF-kappaB,KEGG:mmu:18036`KO:K02581,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^4-34^E:1.7e-06,PF13606.6^Ank_3^Ankyrin repeat^4-32^E:2.7e-06,PF13637.6^Ank_4^Ankyrin repeats (many copies)^5-45^E:6.4e-05,NA,NA,,
yes,AD,NF-kappa-B,DN2830_c2_g1_i4,DN2830_c2_g1,IKBB_MOUSE,NF-kappa-B inhibitor beta,IKBB_MOUSE,NF-kappa-B inhibitor beta,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007253^biological_process^cytoplasmic sequestering of NF-kappaB,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007253^biological_process^cytoplasmic sequestering of NF-kappaB,KEGG:mmu:18036`KO:K02581,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^4-34^E:1.6e-06,PF13606.6^Ank_3^Ankyrin repeat^4-32^E:2.5e-06,PF13637.6^Ank_4^Ankyrin repeats (many copies)^5-45^E:6e-05,NA,NA,,
yes,AD,NF-kappa-B,DN2830_c2_g2_i2,DN2830_c2_g2,IKBB_HUMAN,NF-kappa-B inhibitor beta,IKBB_HUMAN,NF-kappa-B inhibitor beta,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003713^molecular_function^transcription coactivator activity,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007165^biological_process^signal transduction,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003713^molecular_function^transcription coactivator activity,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007165^biological_process^signal transduction,KEGG:hsa:4793`KO:K02581,COG0666^Ankyrin Repeat,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^99-187^E:9.9e-13,PF00023.30^Ank^Ankyrin repeat^117-138^E:0.0029,PF00023.30^Ank^Ankyrin repeat^158-186^E:2.2e-07,PF13606.6^Ank_3^Ankyrin repeat^158-186^E:1.6e-05,PF13606.6^Ank_3^Ankyrin repeat^222-250^E:1.2e-05,,
yes,AD,NF-kappa-B,DN2830_c2_g2_i1,DN2830_c2_g2,IKBB_HUMAN,NF-kappa-B inhibitor beta,IKBB_HUMAN,NF-kappa-B inhibitor beta,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003713^molecular_function^transcription coactivator activity,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007165^biological_process^signal transduction,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0003713^molecular_function^transcription coactivator activity,GO:0071222^biological_process^cellular response to lipopolysaccharide,GO:0007165^biological_process^signal transduction,KEGG:hsa:4793`KO:K02581,COG0666^Ankyrin Repeat,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^99-187^E:6.3e-13,PF00023.30^Ank^Ankyrin repeat^117-138^E:0.0025,PF00023.30^Ank^Ankyrin repeat^158-186^E:1.9e-07,PF13606.6^Ank_3^Ankyrin repeat^158-186^E:1.4e-05,PF13637.6^Ank_4^Ankyrin repeats (many copies)^160-213^E:9.3e-11,,
yes,AD,NF-kappa-B,DN86248_c0_g1_i1,DN86248_c0_g1,KBRS2_MOUSE,NF-kappa-B inhibitor-interacting Ras-like protein 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,.,NA,NA,NA,NA,KEGG:mmu:71966`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN99300_c0_g1_i2,DN99300_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,.,NA,NA,NA,NA,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN7590_c0_g2_i6,DN7590_c0_g2,IKBD_MOUSE,NF-kappa-B inhibitor delta,IKBD_MOUSE,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:mmu:243910`KO:K14214,COG0666^Ankyrin Repeat,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^116-181^E:4e-06,PF13857.6^Ank_5^Ankyrin repeats (many copies)^121-175^E:3.6e-06,PF00023.30^Ank^Ankyrin repeat^135-167^E:0.0047,PF00023.30^Ank^Ankyrin repeat^170-222^E:0.0033,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^207-295^E:1.5e-10,,
yes,AD,NF-kappa-B,DN7590_c0_g2_i9,DN7590_c0_g2,IKBD_HUMAN,NF-kappa-B inhibitor delta,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^39-74^E:6.1e-06,PF13606.6^Ank_3^Ankyrin repeat^39-71^E:0.0024,NA,NA,NA,,
yes,AD,NF-kappa-B,DN7590_c0_g2_i1,DN7590_c0_g2,IKBD_MOUSE,NF-kappa-B inhibitor delta,IKBD_HUMAN,NF-kappa-B inhibitor delta,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,GO:0005634^cellular_component^nucleus,GO:0051059^molecular_function^NF-kappaB binding,GO:0006954^biological_process^inflammatory response,GO:0043124^biological_process^negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0032088^biological_process^negative regulation of NF-kappaB transcription factor activity,KEGG:hsa:84807`KO:K14214,COG0666^Ankyrin Repeat,PF00023.30^Ank^Ankyrin repeat^16-68^E:0.0016,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^53-141^E:6.2e-11,PF00023.30^Ank^Ankyrin repeat^107-142^E:2e-05,NA,NA,,
yes,AD,NF-kappa-B,DN40061_c0_g1_i1,DN40061_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,.,NA,NA,NA,NA,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN772_c3_g3_i1,DN772_c3_g3,NKAP_RAT,NF-kappa-B-activating protein,.,NA,GO:0005634^cellular_component^nucleus,GO:0003682^molecular_function^chromatin binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0007219^biological_process^Notch signaling pathway,GO:0046638^biological_process^positive regulation of alpha-beta T cell differentiation,.,NA,NA,NA,NA,KEGG:rno:298342,ENOG4111VW4^NF-kB activating protein,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN18242_c0_g1_i1,DN18242_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g1_i7,DN32095_c0_g1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^6-109^E:1.1e-13,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^6-105^E:1.3e-08",PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^6-95^E:7.6e-06,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g1_i6,DN32095_c0_g1,KBRS1_MACFA,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00025.21^Arf^ADP-ribosylation factor family^3-157^E:8e-09,PF00071.22^Ras^Ras family^6-168^E:3.9e-26,"PF08477.13^Roc^Ras of Complex, Roc, domain of DAPkinase^6-123^E:5.5e-11",PF01926.23^MMR_HSR1^50S ribosome-binding GTPase^6-117^E:6.6e-06,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g1_i5,DN32095_c0_g1,KBRS1_MACFA,NF-kappa-B inhibitor-interacting Ras-like protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,.,NA,NA,NA,NA,KEGG:mcf:102137307`KO:K17197,.,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g1_i3,DN32095_c0_g1,KBRS1_MACFA,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^3-130^E:3.2e-20,PF00025.21^Arf^ADP-ribosylation factor family^18-120^E:3.2e-05,NA,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g1_i4,DN32095_c0_g1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^45-179^E:5e-21,PF00025.21^Arf^ADP-ribosylation factor family^67-168^E:6.5e-05,PF14049.6^Dppa2_A^Dppa2/4 conserved region in higher vertebrates^130-191^E:1.3,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g2_i2,DN32095_c0_g2,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^40-86^E:2.3e-05,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN32095_c0_g2_i1,DN32095_c0_g2,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,KBRS1_HUMAN,NF-kappa-B inhibitor-interacting Ras-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,GO:0005737^cellular_component^cytoplasm,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0007249^biological_process^I-kappaB kinase/NF-kappaB signaling,NA,KEGG:hsa:28512`KO:K17197,ENOG4110VES^NFKB inhibitor interacting Ras-like,PF00071.22^Ras^Ras family^40-90^E:9.3e-06,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN124001_c0_g1_i1,DN124001_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN124001_c0_g1_i2,DN124001_c0_g1,NFKB1_CHICK,Nuclear factor NF-kappa-B p105 subunit,.,NA,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0042805^molecular_function^actinin binding,GO:0003682^molecular_function^chromatin binding,.,NA,NA,NA,NA,KEGG:gga:396033`KO:K02580,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN106894_c0_g1_i1,DN106894_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,.,NA,NA,NA,NA,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NF-kappa-B,DN221914_c0_g1_i4,DN221914_c0_g1,NFKB2_CHICK,Nuclear factor NF-kappa-B p100 subunit,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0048511^biological_process^rhythmic process,.,NA,NA,NA,NA,KEGG:gga:386574`KO:K04469,COG0666^Ankyrin Repeat,.,NA,NA,NA,NA,,
yes,AD,NFRKB,DN4096_c0_g1_i3,DN4096_c0_g1,NFRKB_HUMAN,Nuclear factor related to kappa-B-binding protein,NFRKB_MOUSE,Nuclear factor related to kappa-B-binding protein,GO:0031011^cellular_component^Ino80 complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,GO:0031011^cellular_component^Ino80 complex,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,GO:0006310^biological_process^DNA recombination,KEGG:mmu:235134`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,PF14465.6^NFRKB_winged^NFRKB Winged Helix-like^379-478^E:1.3e-31,NA,NA,NA,NA,,
yes,AD,NFRKB,DN16885_c0_g1_i1,DN16885_c0_g1,NFRKB_HUMAN,Nuclear factor related to kappa-B-binding protein,.,NA,GO:0031011^cellular_component^Ino80 complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,.,NA,NA,NA,NA,KEGG:hsa:4798`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,.,NA,NA,NA,NA,,
yes,AD,NFRKB,DN16885_c0_g1_i2,DN16885_c0_g1,NFRKB_HUMAN,Nuclear factor related to kappa-B-binding protein,.,NA,GO:0031011^cellular_component^Ino80 complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,.,NA,NA,NA,NA,KEGG:hsa:4798`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,.,NA,NA,NA,NA,,
yes,AD,NFRKB,DN82684_c0_g1_i1,DN82684_c0_g1,NFRKB_MOUSE,Nuclear factor related to kappa-B-binding protein,.,NA,GO:0031011^cellular_component^Ino80 complex,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,GO:0006310^biological_process^DNA recombination,.,NA,NA,NA,NA,KEGG:mmu:235134`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,.,NA,NA,NA,NA,,
yes,AD,NFRKB,DN233511_c0_g1_i1,DN233511_c0_g1,NFRKB_HUMAN,Nuclear factor related to kappa-B-binding protein,.,NA,GO:0031011^cellular_component^Ino80 complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,.,NA,NA,NA,NA,KEGG:hsa:4798`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,.,NA,NA,NA,NA,,
yes,AD,NFRKB,DN336317_c0_g1_i1,DN336317_c0_g1,NFRKB_HUMAN,Nuclear factor related to kappa-B-binding protein,.,NA,GO:0031011^cellular_component^Ino80 complex,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0002020^molecular_function^protease binding,.,NA,NA,NA,NA,KEGG:hsa:4798`KO:K11671,ENOG410YHF2^Nuclear factor related to kappaB binding protein,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN19731_c0_g2_i1,DN19731_c0_g2,NLRC3_MOUSE,Protein NLRC3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:268857,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN7775_c0_g1_i1,DN7775_c0_g1,NLRC3_MOUSE,Protein NLRC3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:268857,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN7775_c0_g1_i2,DN7775_c0_g1,NLRC3_MOUSE,Protein NLRC3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:268857,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN17674_c1_g1_i1,DN17674_c1_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:197358`KO:K22614,.,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN2695_c0_g1_i2,DN2695_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:hsa:197358`KO:K22614,.,PF00619.21^CARD^Caspase recruitment domain^4-87^E:4.6e-06,PF13516.6^LRR_6^Leucine Rich repeat^27-34^E:2000,PF05729.12^NACHT^NACHT domain^168-333^E:3.9e-27,PF17779.1^NOD2_WH^NOD2 winged helix domain^425-481^E:4.3e-16,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^483-609^E:1.8e-23,,
yes,AD,NLRC,DN2695_c0_g1_i3,DN2695_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:197358`KO:K22614,.,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN2695_c0_g1_i4,DN2695_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:hsa:197358`KO:K22614,.,PF13516.6^LRR_6^Leucine Rich repeat^9-31^E:3.5,PF00560.33^LRR_1^Leucine Rich Repeat^12-23^E:1800,PF13516.6^LRR_6^Leucine Rich repeat^36-59^E:0.003,PF00560.33^LRR_1^Leucine Rich Repeat^40-49^E:1100,PF13516.6^LRR_6^Leucine Rich repeat^65-87^E:1.3,,
yes,AD,NLRC,DN2695_c0_g1_i10,DN2695_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,KEGG:hsa:197358`KO:K22614,.,PF00619.21^CARD^Caspase recruitment domain^4-87^E:3.1e-06,PF13516.6^LRR_6^Leucine Rich repeat^27-34^E:1500,PF05729.12^NACHT^NACHT domain^168-333^E:2.5e-27,PF17779.1^NOD2_WH^NOD2 winged helix domain^425-481^E:3e-16,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^483-609^E:1.2e-23,,
yes,AD,NLRC,DN3089_c0_g1_i9,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,NLRC5_HUMAN,Protein NLRC5,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",PF00560.33^LRR_1^Leucine Rich Repeat^51-61^E:18000,PF13516.6^LRR_6^Leucine Rich repeat^74-95^E:0.0019,PF00560.33^LRR_1^Leucine Rich Repeat^79-99^E:11,PF13516.6^LRR_6^Leucine Rich repeat^104-124^E:190,PF00560.33^LRR_1^Leucine Rich Repeat^105-115^E:530,,
yes,AD,NLRC,DN3089_c0_g1_i13,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,NLRC5_HUMAN,Protein NLRC5,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",PF18461.1^Atypical_Card^Atypical caspase recruitment domain^7-99^E:3.2e-31,PF05729.12^NACHT^NACHT domain^241-411^E:3.8e-35,PF00004.29^AAA^ATPase family associated with various cellular activities (AAA)^243-384^E:3.1e-06,PF17779.1^NOD2_WH^NOD2 winged helix domain^495-551^E:6.4e-07,PF17776.1^NLRC4_HD2^NLRC4 helical domain HD2^553-668^E:6e-21,,
yes,AD,NLRC,DN3089_c0_g1_i7,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,NLRC5_HUMAN,Protein NLRC5,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",PF13516.6^LRR_6^Leucine Rich repeat^1-9^E:1300,PF13516.6^LRR_6^Leucine Rich repeat^22-43^E:0.0024,PF00560.33^LRR_1^Leucine Rich Repeat^23-34^E:98,PF13516.6^LRR_6^Leucine Rich repeat^52-63^E:84,PF00560.33^LRR_1^Leucine Rich Repeat^52-68^E:170,,
yes,AD,NLRC,DN3089_c0_g1_i12,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",.,NA,NA,NA,NA,,
yes,AD,NLRC,DN3089_c0_g1_i6,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",.,NA,NA,NA,NA,,
yes,AD,NLRC,DN3089_c0_g1_i4,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",.,NA,NA,NA,NA,,
yes,AD,NLRC,DN3089_c0_g1_i3,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",.,NA,NA,NA,NA,,
yes,AD,NLRC,DN3089_c0_g1_i1,DN3089_c0_g1,NLRC5_HUMAN,Protein NLRC5,.,NA,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:84166`KO:K22615,"ENOG4112B0K^NLR family, CARD domain containing 5",.,NA,NA,NA,NA,,
yes,AD,NLRC,DN38343_c0_g1_i2,DN38343_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:197358`KO:K22614,.,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN38343_c0_g1_i1,DN38343_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:197358`KO:K22614,.,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN38343_c0_g1_i3,DN38343_c0_g1,NLRC3_HUMAN,NLR family CARD domain-containing protein 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:197358`KO:K22614,.,.,NA,NA,NA,NA,,
yes,AD,NLRC,DN234909_c0_g1_i1,DN234909_c0_g1,NLRC3_MOUSE,Protein NLRC3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005815^cellular_component^microtubule organizing center,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:mmu:268857,ENOG410ZBX3^leucine Rich Repeat,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i9,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO1_HUMAN,Nodal modulator 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:23420,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i18,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO2_HUMAN,Nodal modulator 2,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:283820,ENOG410XTI0^nodal modulator,PF13620.6^CarboxypepD_reg^Carboxypeptidase regulatory-like domain^373-431^E:7.1e-09,PF09430.10^DUF2012^Protein of unknown function (DUF2012)^387-441^E:1.5e-07,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i8,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO2_HUMAN,Nodal modulator 2,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:283820,ENOG410XTI0^nodal modulator,PF13620.6^CarboxypepD_reg^Carboxypeptidase regulatory-like domain^373-431^E:4.1e-09,PF09430.10^DUF2012^Protein of unknown function (DUF2012)^387-441^E:8.8e-08,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i14,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,.,NA,NA,NA,NA,KEGG:hsa:283820,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i1,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO2_HUMAN,Nodal modulator 2,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:283820,ENOG410XTI0^nodal modulator,PF13620.6^CarboxypepD_reg^Carboxypeptidase regulatory-like domain^373-431^E:9.4e-09,PF09430.10^DUF2012^Protein of unknown function (DUF2012)^387-441^E:2.1e-07,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i17,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO1_HUMAN,Nodal modulator 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:23420,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i11,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO2_HUMAN,Nodal modulator 2,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:283820,ENOG410XTI0^nodal modulator,PF13620.6^CarboxypepD_reg^Carboxypeptidase regulatory-like domain^373-431^E:6.3e-09,PF09430.10^DUF2012^Protein of unknown function (DUF2012)^387-441^E:1.3e-07,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i4,DN6012_c0_g1,NOMO2_HUMAN,Nodal modulator 2,NOMO1_HUMAN,Nodal modulator 1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0030246^molecular_function^carbohydrate binding,NA,KEGG:hsa:23420,ENOG410XTI0^nodal modulator,PF13620.6^CarboxypepD_reg^Carboxypeptidase regulatory-like domain^373-431^E:1e-08,PF09430.10^DUF2012^Protein of unknown function (DUF2012)^387-441^E:2.3e-07,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i3,DN6012_c0_g1,NOMO3_HUMAN,Nodal modulator 3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:408050,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN6012_c0_g1_i5,DN6012_c0_g1,NOMO3_HUMAN,Nodal modulator 3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:408050,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN90717_c0_g1_i1,DN90717_c0_g1,NOMO1_MOUSE,Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0032991^cellular_component^protein-containing complex,GO:0030246^molecular_function^carbohydrate binding,NA,.,NA,NA,NA,NA,KEGG:mmu:211548,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN238331_c0_g1_i1,DN238331_c0_g1,NOMO3_HUMAN,Nodal modulator 3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:408050,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
yes,AD,NODAL,DN304724_c0_g1_i1,DN304724_c0_g1,NOMO3_HUMAN,Nodal modulator 3,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0030246^molecular_function^carbohydrate binding,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:408050,ENOG410XTI0^nodal modulator,.,NA,NA,NA,NA,,
no,AD,NRG,DN3816_c0_g2_i8,DN3816_c0_g2,SYNRG_HUMAN,Synergin gamma,SYNRG_HUMAN,Synergin gamma,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,KEGG:hsa:11276,ENOG410Z4AG^synergin gamma,.,NA,NA,NA,NA,,
no,AD,NRG,DN3816_c0_g2_i6,DN3816_c0_g2,SYNRG_HUMAN,Synergin gamma,SYNRG_HUMAN,Synergin gamma,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,KEGG:hsa:11276,ENOG410Z4AG^synergin gamma,.,NA,NA,NA,NA,,
no,AD,NRG,DN3816_c0_g2_i9,DN3816_c0_g2,SYNRG_HUMAN,Synergin gamma,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:hsa:11276,ENOG410Z4AG^synergin gamma,.,NA,NA,NA,NA,,
no,AD,NRG,DN3816_c0_g2_i3,DN3816_c0_g2,SYNRG_HUMAN,Synergin gamma,.,NA,GO:0030121^cellular_component^AP-1 adaptor complex,GO:0005737^cellular_component^cytoplasm,GO:0005794^cellular_component^Golgi apparatus,GO:0006897^biological_process^endocytosis,GO:0006886^biological_process^intracellular protein transport,.,NA,NA,NA,NA,KEGG:hsa:11276,ENOG410Z4AG^synergin gamma,.,NA,NA,NA,NA,,
no,AD,NRG,DN2077_c0_g1_i21,DN2077_c0_g1,C19L1_PONAB,CWF19-like protein 1,C19L1_PONAB,CWF19-like protein 1,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^329-436^E:2.6e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^455-543^E:1.6e-14,NA,NA,NA,,
no,AD,NRG,DN2077_c0_g1_i15,DN2077_c0_g1,C19L1_PONAB,CWF19-like protein 1,C19L1_PONAB,CWF19-like protein 1,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^329-436^E:2.6e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^455-543^E:1.6e-14,NA,NA,NA,,
yes,AD,NRG,DN2077_c0_g1_i22,DN2077_c0_g1,IKKA_CHICK,Inhibitor of nuclear factor kappa-B kinase subunit alpha,C19L1_PONAB,CWF19-like protein 1,GO:0005829^cellular_component^cytosol,GO:0008385^cellular_component^IkappaB kinase complex,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0008384^molecular_function^IkappaB kinase activity,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^283-390^E:2.2e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^409-497^E:1.4e-14,NA,NA,NA,,
no,AD,NRG,DN2077_c0_g1_i20,DN2077_c0_g1,C19L1_PONAB,CWF19-like protein 1,C19L1_PONAB,CWF19-like protein 1,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^329-436^E:2.6e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^455-543^E:1.6e-14,NA,NA,NA,,
no,AD,NRG,DN2077_c0_g1_i7,DN2077_c0_g1,C19L1_PONAB,CWF19-like protein 1,C19L1_PONAB,CWF19-like protein 1,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^329-436^E:2.6e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^455-543^E:1.6e-14,NA,NA,NA,,
no,AD,NRG,DN2077_c0_g1_i16,DN2077_c0_g1,C19L1_PONAB,CWF19-like protein 1,C19L1_PONAB,CWF19-like protein 1,.,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^283-390^E:2.2e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^409-497^E:1.4e-14,NA,NA,NA,,
yes,AD,NRG,DN2077_c0_g1_i9,DN2077_c0_g1,IKKA_CHICK,Inhibitor of nuclear factor kappa-B kinase subunit alpha,C19L1_PONAB,CWF19-like protein 1,GO:0005829^cellular_component^cytosol,GO:0008385^cellular_component^IkappaB kinase complex,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0008384^molecular_function^IkappaB kinase activity,.,NA,NA,NA,NA,KEGG:pon:100173021,"ENOG410XNRG^CWF19-like 1, cell cycle control (S. pombe)",PF04677.15^CwfJ_C_1^Protein similar to CwfJ C-terminus 1^283-390^E:2.2e-33,PF04676.14^CwfJ_C_2^Protein similar to CwfJ C-terminus 2^409-497^E:1.4e-14,NA,NA,NA,,
yes,AD,NRG,DN9494_c0_g1_i5,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:gga:373906`KO:K05455,ENOG4110ST7^Neuregulin 1,PF13927.6^Ig_3^Immunoglobulin domain^69-149^E:1.1e-11,PF07679.16^I-set^Immunoglobulin I-set domain^74-163^E:3.3e-14,PF00047.25^ig^Immunoglobulin domain^76-160^E:1.5e-10,PF13895.6^Ig_2^Immunoglobulin domain^76-162^E:6.4e-09,PF07686.17^V-set^Immunoglobulin V-set domain^77-154^E:7.3e-06,,
yes,AD,NRG,DN9494_c0_g1_i2,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:gga:373906`KO:K05455,ENOG4110ST7^Neuregulin 1,PF13927.6^Ig_3^Immunoglobulin domain^69-149^E:2.1e-12,PF07679.16^I-set^Immunoglobulin I-set domain^74-163^E:5.6e-15,PF00047.25^ig^Immunoglobulin domain^76-160^E:2.7e-11,PF13895.6^Ig_2^Immunoglobulin domain^76-162^E:1.1e-09,PF07686.17^V-set^Immunoglobulin V-set domain^77-155^E:1.3e-06,,
yes,AD,NRG,DN9494_c0_g1_i7,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",NRG1_HUMAN,"Pro-neuregulin-1, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,KEGG:hsa:3084`KO:K05455,ENOG4110ST7^Neuregulin 1,PF13927.6^Ig_3^Immunoglobulin domain^69-149^E:2.7e-12,PF07679.16^I-set^Immunoglobulin I-set domain^74-163^E:7.4e-15,PF00047.25^ig^Immunoglobulin domain^76-160^E:3.5e-11,PF13895.6^Ig_2^Immunoglobulin domain^76-162^E:1.4e-09,PF07686.17^V-set^Immunoglobulin V-set domain^77-155^E:1.7e-06,,
yes,AD,NRG,DN9494_c0_g1_i4,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:gga:373906`KO:K05455,ENOG4110ST7^Neuregulin 1,PF13927.6^Ig_3^Immunoglobulin domain^69-149^E:1.1e-11,PF07679.16^I-set^Immunoglobulin I-set domain^74-163^E:3.3e-14,PF00047.25^ig^Immunoglobulin domain^76-160^E:1.5e-10,PF13895.6^Ig_2^Immunoglobulin domain^76-162^E:6.3e-09,PF07686.17^V-set^Immunoglobulin V-set domain^77-154^E:7.2e-06,,
yes,AD,NRG,DN9494_c0_g1_i3,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",.,NA,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:gga:373906`KO:K05455,ENOG4110ST7^Neuregulin 1,.,NA,NA,NA,NA,,
yes,AD,NRG,DN9494_c0_g1_i1,DN9494_c0_g1,NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",NRG1_CHICK,"Pro-neuregulin-1, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0043125^molecular_function^ErbB-3 class receptor binding,GO:0008083^molecular_function^growth factor activity,KEGG:gga:373906`KO:K05455,ENOG4110ST7^Neuregulin 1,PF13927.6^Ig_3^Immunoglobulin domain^69-149^E:1.1e-11,PF07679.16^I-set^Immunoglobulin I-set domain^74-163^E:3.2e-14,PF00047.25^ig^Immunoglobulin domain^76-160^E:1.5e-10,PF13895.6^Ig_2^Immunoglobulin domain^76-162^E:6.3e-09,PF07686.17^V-set^Immunoglobulin V-set domain^77-154^E:7.1e-06,,
no,AD,NRG,DN4350_c0_g1_i6,DN4350_c0_g1,TRI13_HUMAN,E3 ubiquitin-protein ligase TRIM13,KCNRG_XENTR,Putative potassium channel regulatory protein,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0044322^cellular_component^endoplasmic reticulum quality control compartment,GO:0016021^cellular_component^integral component of membrane,GO:0097038^cellular_component^perinuclear endoplasmic reticulum,GO:0005783^cellular_component^endoplasmic reticulum,GO:1902260^biological_process^negative regulation of delayed rectifier potassium channel activity,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:xtr:394457,ENOG410YH9X^tripartite motif containing,PF02214.22^BTB_2^BTB/POZ domain^7-94^E:1.2e-19,NA,NA,NA,NA,,
no,AD,NRG,DN4350_c0_g1_i2,DN4350_c0_g1,TRI13_HUMAN,E3 ubiquitin-protein ligase TRIM13,KCNRG_XENTR,Putative potassium channel regulatory protein,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0044322^cellular_component^endoplasmic reticulum quality control compartment,GO:0016021^cellular_component^integral component of membrane,GO:0097038^cellular_component^perinuclear endoplasmic reticulum,GO:0005783^cellular_component^endoplasmic reticulum,GO:1902260^biological_process^negative regulation of delayed rectifier potassium channel activity,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:xtr:394457,ENOG410YH9X^tripartite motif containing,PF02214.22^BTB_2^BTB/POZ domain^7-94^E:1.2e-19,NA,NA,NA,NA,,
yes,AD,NRG,DN84006_c0_g1_i1,DN84006_c0_g1,NRG3_HUMAN,"Pro-neuregulin-3, membrane-bound isoform",NRG3_HUMAN,"Pro-neuregulin-3, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045499^molecular_function^chemorepellent activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045499^molecular_function^chemorepellent activity,KEGG:hsa:10718`KO:K05457,ENOG4111KAZ^neuregulin 3,.,NA,NA,NA,NA,,
yes,AD,NRG,DN84006_c0_g1_i2,DN84006_c0_g1,NRG3_HUMAN,"Pro-neuregulin-3, membrane-bound isoform",NRG3_HUMAN,"Pro-neuregulin-3, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045499^molecular_function^chemorepellent activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0005887^cellular_component^integral component of plasma membrane,GO:0045499^molecular_function^chemorepellent activity,KEGG:hsa:10718`KO:K05457,ENOG4111KAZ^neuregulin 3,.,NA,NA,NA,NA,,
yes,AD,NRG,DN84006_c0_g1_i4,DN84006_c0_g1,NRG3_MOUSE,"Pro-neuregulin-3, membrane-bound isoform",.,NA,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,.,NA,NA,NA,NA,KEGG:mmu:18183`KO:K05457,ENOG4111KAZ^neuregulin 3,.,NA,NA,NA,NA,,
yes,AD,NRG,DN84006_c0_g1_i3,DN84006_c0_g1,NRG3_MOUSE,"Pro-neuregulin-3, membrane-bound isoform",.,NA,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,.,NA,NA,NA,NA,KEGG:mmu:18183`KO:K05457,ENOG4111KAZ^neuregulin 3,.,NA,NA,NA,NA,,
no,AD,NRG,DN20763_c0_g1_i4,DN20763_c0_g1,TRI13_HUMAN,E3 ubiquitin-protein ligase TRIM13,KCNRG_XENTR,Putative potassium channel regulatory protein,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0044322^cellular_component^endoplasmic reticulum quality control compartment,GO:0016021^cellular_component^integral component of membrane,GO:0097038^cellular_component^perinuclear endoplasmic reticulum,GO:0005783^cellular_component^endoplasmic reticulum,GO:1902260^biological_process^negative regulation of delayed rectifier potassium channel activity,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:xtr:394457,ENOG410YH9X^tripartite motif containing,PF02214.22^BTB_2^BTB/POZ domain^7-94^E:2.8e-19,NA,NA,NA,NA,,
no,AD,NRG,DN20763_c0_g1_i6,DN20763_c0_g1,TRI13_HUMAN,E3 ubiquitin-protein ligase TRIM13,KCNRG_XENTR,Putative potassium channel regulatory protein,GO:0005737^cellular_component^cytoplasm,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0044322^cellular_component^endoplasmic reticulum quality control compartment,GO:0016021^cellular_component^integral component of membrane,GO:0097038^cellular_component^perinuclear endoplasmic reticulum,GO:0005783^cellular_component^endoplasmic reticulum,GO:1902260^biological_process^negative regulation of delayed rectifier potassium channel activity,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:xtr:394457,ENOG410YH9X^tripartite motif containing,PF02214.22^BTB_2^BTB/POZ domain^7-94^E:2.8e-19,NA,NA,NA,NA,,
no,AD,NRG,DN20763_c1_g1_i7,DN20763_c1_g1,KCNRG_HUMAN,Potassium channel regulatory protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0042802^molecular_function^identical protein binding,GO:1902260^biological_process^negative regulation of delayed rectifier potassium channel activity,GO:0051260^biological_process^protein homooligomerization,NA,.,NA,NA,NA,NA,KEGG:hsa:283518,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i12,DN10155_c0_g1,NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:9542`KO:K05456,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^40-397^E:5.2e-168,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i3,DN10155_c0_g1,NRG2_RAT,"Pro-neuregulin-2, membrane-bound isoform",NRG2_RAT,"Pro-neuregulin-2, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,KEGG:rno:432361`KO:K05456,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^71-270^E:3.7e-79,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i6,DN10155_c0_g1,NRG2_RAT,"Pro-neuregulin-2, membrane-bound isoform",.,NA,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:rno:432361`KO:K05456,ENOG410Y95Z^neuregulin 2,.,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i1,DN10155_c0_g1,NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,.,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^1-351^E:3.6e-162,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i13,DN10155_c0_g1,NRG2_RAT,"Pro-neuregulin-2, membrane-bound isoform",.,NA,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:rno:432361`KO:K05456,ENOG410Y95Z^neuregulin 2,.,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i10,DN10155_c0_g1,NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,.,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^1-351^E:3.6e-162,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i4,DN10155_c0_g1,NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,.,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^1-351^E:3.6e-162,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i8,DN10155_c0_g1,NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:9542`KO:K05456,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^40-397^E:5.2e-168,NA,NA,NA,NA,,
yes,AD,NRG,DN10155_c0_g1_i14,DN10155_c0_g1,NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:9542`KO:K05456,ENOG410Y95Z^neuregulin 2,PF13927.6^Ig_3^Immunoglobulin domain^32-111^E:1.6e-16,PF07679.16^I-set^Immunoglobulin I-set domain^36-124^E:2.8e-19,PF00047.25^ig^Immunoglobulin domain^39-118^E:3.1e-13,PF13895.6^Ig_2^Immunoglobulin domain^40-122^E:1.5e-13,PF02158.15^Neuregulin^Neuregulin intracellular region^248-605^E:1.9e-167,,
yes,AD,NRG,DN10155_c0_g1_i7,DN10155_c0_g1,NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",NRG2_HUMAN,"Pro-neuregulin-2, membrane-bound isoform",GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:9542`KO:K05456,ENOG410Y95Z^neuregulin 2,PF13927.6^Ig_3^Immunoglobulin domain^32-111^E:1.5e-16,PF07679.16^I-set^Immunoglobulin I-set domain^36-124^E:2.7e-19,PF00047.25^ig^Immunoglobulin domain^39-118^E:2.9e-13,PF13895.6^Ig_2^Immunoglobulin domain^40-122^E:1.4e-13,PF02158.15^Neuregulin^Neuregulin intracellular region^226-583^E:1.7e-167,,
yes,AD,NRG,DN10155_c0_g1_i5,DN10155_c0_g1,NRG2_RAT,"Pro-neuregulin-2, membrane-bound isoform",NRG2_MOUSE,"Pro-neuregulin-2, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005615^cellular_component^extracellular space,GO:0098982^cellular_component^GABA-ergic synapse,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,KEGG:rno:432361`KO:K05456,ENOG410Y95Z^neuregulin 2,PF02158.15^Neuregulin^Neuregulin intracellular region^64-421^E:6.4e-168,NA,NA,NA,NA,,
no,AD,NRG,DN232621_c0_g1_i1,DN232621_c0_g1,SYNRG_MOUSE,Synergin gamma,.,NA,GO:0030130^cellular_component^clathrin coat of trans-Golgi network vesicle,GO:0005829^cellular_component^cytosol,GO:0006897^biological_process^endocytosis,GO:0015031^biological_process^protein transport,NA,.,NA,NA,NA,NA,KEGG:mmu:217030,"ENOG410XU79^synergin, gamma",.,NA,NA,NA,NA,,
yes,AD,NRG,DN389437_c0_g1_i1,DN389437_c0_g1,NRG3_MOUSE,"Pro-neuregulin-3, membrane-bound isoform",NRG3_MOUSE,"Pro-neuregulin-3, membrane-bound isoform",GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,GO:0005615^cellular_component^extracellular space,GO:0098978^cellular_component^glutamatergic synapse,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0045499^molecular_function^chemorepellent activity,KEGG:mmu:18183`KO:K05457,ENOG4111KAZ^neuregulin 3,.,NA,NA,NA,NA,,
yes,AD,OASL,DN15488_c0_g1_i1,DN15488_c0_g1,OASL2_RAT,2'-5'-oligoadenylate synthase-like protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0001730^molecular_function^2'-5'-oligoadenylate synthetase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:rno:304549`KO:K14608,COG5272^ubiquitin,.,NA,NA,NA,NA,,
yes,AD,OASL,DN6190_c0_g1_i1,DN6190_c0_g1,OASL1_RAT,2'-5'-oligoadenylate synthase-like protein 1,OAS3_MOUSE,2'-5'-oligoadenylate synthase 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,KEGG:mmu:246727`KO:K14216,COG5272^ubiquitin,PF01909.23^NTP_transf_2^Nucleotidyltransferase domain^36-93^E:2.6e-07,"PF10421.9^OAS1_C^2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus^156-287^E:2.3e-56",NA,NA,NA,,
yes,AD,OASL,DN6190_c0_g1_i4,DN6190_c0_g1,OASL2_MOUSE,2'-5'-oligoadenylate synthase-like protein 2,OASL1_RAT,2'-5'-oligoadenylate synthase-like protein 1,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0001730^molecular_function^2'-5'-oligoadenylate synthetase activity,GO:0005524^molecular_function^ATP binding,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:rno:304545`KO:K14608,COG5272^ubiquitin,"PF10421.9^OAS1_C^2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus^2-49^E:1.8e-10",PF00240.23^ubiquitin^Ubiquitin family^57-128^E:9.6e-08,PF14560.6^Ubiquitin_2^Ubiquitin-like domain^66-117^E:0.0051,PF11976.8^Rad60-SLD^Ubiquitin-2 like Rad60 SUMO-like^133-199^E:5.2e-11,PF00240.23^ubiquitin^Ubiquitin family^135-206^E:1.7e-23,,
yes,AD,OASL,DN6190_c0_g1_i2,DN6190_c0_g1,OASL1_RAT,2'-5'-oligoadenylate synthase-like protein 1,OASL1_RAT,2'-5'-oligoadenylate synthase-like protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:rno:304545`KO:K14608,COG5272^ubiquitin,PF01909.23^NTP_transf_2^Nucleotidyltransferase domain^36-92^E:6.7e-07,"PF10421.9^OAS1_C^2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus^156-333^E:1.4e-73",PF00240.23^ubiquitin^Ubiquitin family^341-412^E:4.1e-07,PF14560.6^Ubiquitin_2^Ubiquitin-like domain^350-401^E:0.02,PF11976.8^Rad60-SLD^Ubiquitin-2 like Rad60 SUMO-like^417-483^E:2.1e-10,,
yes,AD,OASL,DN17476_c0_g1_i2,DN17476_c0_g1,OASL2_RAT,2'-5'-oligoadenylate synthase-like protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0001730^molecular_function^2'-5'-oligoadenylate synthetase activity,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:rno:304549`KO:K14608,COG5272^ubiquitin,.,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i8,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^33-81^E:2.6e-08,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i2,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^3-158^E:1.3e-36,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i11,DN20874_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF18606.1^HTH_53^Zap helix turn helix N-terminal domain^37-87^E:3e-21,PF02825.20^WWE^WWE domain^443-518^E:1.3e-15,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i10,DN20874_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^8-92^E:3.7e-15,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i3,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^8-92^E:3.7e-15,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i4,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^9-57^E:1.6e-08,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i1,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^9-57^E:1.7e-08,NA,NA,NA,NA,,
yes,AD,PARP12,DN20874_c0_g1_i9,DN20874_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,KEGG:mmu:243771`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^9-57^E:1.3e-07,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^108-279^E:8.9e-40,NA,NA,NA,,
yes,AD,PARP12,DN7047_c0_g1_i1,DN7047_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},.,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,.,NA,NA,NA,NA,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",.,NA,NA,NA,NA,,
yes,AD,PARP12,DN7047_c0_g1_i3,DN7047_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^4-76^E:2.9e-13,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^123-294^E:1.4e-33,NA,NA,NA,,
yes,AD,PARP12,DN7047_c0_g1_i4,DN7047_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^4-76^E:2.9e-13,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^123-294^E:1.4e-33,NA,NA,NA,,
yes,AD,PARP12,DN7047_c0_g1_i5,DN7047_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^31-202^E:4.6e-34,NA,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i10,DN5594_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^10-57^E:1.6e-07,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^107-274^E:6.3e-39,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i3,DN5594_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^8-127^E:7.5e-31,NA,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i1,DN5594_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF02825.20^WWE^WWE domain^10-57^E:4.7e-08,NA,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i6,DN5594_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^5-154^E:3.3e-36,NA,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i2,DN5594_c0_g1,PAR12_MOUSE,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0070213^biological_process^protein auto-ADP-ribosylation,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^5-154^E:3.3e-36,NA,NA,NA,NA,,
yes,AD,PARP12,DN5594_c0_g1_i11,DN5594_c0_g1,PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},PAR12_HUMAN,Protein mono-ADP-ribosyltransferase PARP12 {ECO:0000305},GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003950^molecular_function^NAD+ ADP-ribosyltransferase activity,GO:1990404^molecular_function^protein ADP-ribosylase activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:64761`KO:K15259,"ENOG410ZFB8^poly (ADP-ribose) polymerase family, member 12",PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^26-111^E:7.2e-15,NA,NA,NA,NA,,
yes,AD,PARP9,DN17001_c1_g2_i2,DN17001_c1_g2,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,.,NA,NA,NA,NA,,
yes,AD,PARP9,DN17001_c1_g2_i1,DN17001_c1_g2,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,.,NA,NA,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i3,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,.,NA,NA,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i5,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^13-166^E:3.8e-06,NA,NA,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i6,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,PF01661.21^Macro^Macro domain^75-194^E:4.5e-30,PF01661.21^Macro^Macro domain^281-373^E:1.4e-08,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^598-771^E:3.9e-06,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i1,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,PF01661.21^Macro^Macro domain^10-94^E:1.4e-08,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^319-492^E:1.7e-06,NA,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i7,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,PF01661.21^Macro^Macro domain^75-194^E:4.5e-30,PF01661.21^Macro^Macro domain^281-373^E:1.4e-08,PF00644.20^PARP^Poly(ADP-ribose) polymerase catalytic domain^598-771^E:3.9e-06,NA,NA,,
yes,AD,PARP9,DN161_c0_g1_i2,DN161_c0_g1,PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},PARP9_HUMAN,Protein mono-ADP-ribosyltransferase PARP9 {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:83666`KO:K15260,COG2110^appr-1-p processing domain protein,PF01661.21^Macro^Macro domain^90-209^E:9.8e-31,NA,NA,NA,NA,,
yes,AD,PDGFD,DN1091_c2_g1_i4,DN1091_c2_g1,PDGFD_HUMAN,Platelet-derived growth factor D,PDGFD_HUMAN,Platelet-derived growth factor D,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,KEGG:hsa:80310`KO:K05450,ENOG41106HA^Platelet derived growth factor D,PF00431.20^CUB^CUB domain^57-163^E:6.7e-20,PF00341.17^PDGF^PDGF/VEGF domain^282-375^E:1.4e-16,NA,NA,NA,,
yes,AD,PDGFD,DN1091_c2_g1_i2,DN1091_c2_g1,PDGFD_HUMAN,Platelet-derived growth factor D,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:80310`KO:K05450,ENOG41106HA^Platelet derived growth factor D,.,NA,NA,NA,NA,,
yes,AD,PDGFD,DN1091_c2_g1_i3,DN1091_c2_g1,PDGFD_HUMAN,Platelet-derived growth factor D,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:80310`KO:K05450,ENOG41106HA^Platelet derived growth factor D,.,NA,NA,NA,NA,,
yes,AD,PDGFD,DN1091_c2_g1_i6,DN1091_c2_g1,PDGFD_HUMAN,Platelet-derived growth factor D,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:80310`KO:K05450,ENOG41106HA^Platelet derived growth factor D,.,NA,NA,NA,NA,,
yes,AD,PDGFD,DN1091_c2_g1_i1,DN1091_c2_g1,PDGFD_HUMAN,Platelet-derived growth factor D,.,NA,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0000139^cellular_component^Golgi membrane,GO:0008083^molecular_function^growth factor activity,.,NA,NA,NA,NA,KEGG:hsa:80310`KO:K05450,ENOG41106HA^Platelet derived growth factor D,.,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i10,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^94-181^E:9e-16,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^250-317^E:1.1e-21",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^407-486^E:4.9e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^528-633^E:1.7e-13,PF00617.19^RasGEF^RasGEF domain^803-980^E:1.2e-51,,
yes,AD,PGF,DN11648_c0_g1_i4,DN11648_c0_g1,RPGF4_RAT,Rap guanine nucleotide exchange factor 4,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0016323^cellular_component^basolateral plasma membrane,GO:0005903^cellular_component^brush border,GO:0005929^cellular_component^cilium,.,NA,NA,NA,NA,.,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i17,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,.,NA,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,.,NA,NA,NA,NA,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i14,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^84-151^E:9.1e-22",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^241-320^E:3.9e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^362-467^E:1.4e-13,PF00617.19^RasGEF^RasGEF domain^637-814^E:8.8e-52,NA,,
yes,AD,PGF,DN11648_c0_g1_i1,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^94-181^E:9.2e-16,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^268-335^E:1.2e-21",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^425-504^E:5e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^546-651^E:1.8e-13,PF00617.19^RasGEF^RasGEF domain^821-998^E:1.2e-51,,
yes,AD,PGF,DN11648_c0_g1_i8,DN11648_c0_g1,RPGF4_RAT,Rap guanine nucleotide exchange factor 4,RPGF4_RAT,Rap guanine nucleotide exchange factor 4,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0016323^cellular_component^basolateral plasma membrane,GO:0005903^cellular_component^brush border,GO:0005929^cellular_component^cilium,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0016323^cellular_component^basolateral plasma membrane,GO:0005903^cellular_component^brush border,GO:0005929^cellular_component^cilium,.,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00617.19^RasGEF^RasGEF domain^1-52^E:7.4e-11,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i12,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^89-156^E:8.7e-22",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^246-325^E:3.7e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^367-472^E:1.3e-13,PF00617.19^RasGEF^RasGEF domain^642-818^E:2.5e-51,NA,,
yes,AD,PGF,DN11648_c0_g1_i6,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00617.19^RasGEF^RasGEF domain^60-237^E:8.8e-53,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i16,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^92-159^E:9.2e-22",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^249-328^E:3.9e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^370-475^E:1.4e-13,PF00617.19^RasGEF^RasGEF domain^645-822^E:9e-52,NA,,
yes,AD,PGF,DN11648_c0_g1_i11,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^94-181^E:7.9e-16,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^268-335^E:1e-21",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^425-504^E:4.3e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^546-651^E:1.5e-13,PF00617.19^RasGEF^RasGEF domain^821-932^E:3.6e-29,,
yes,AD,PGF,DN11648_c0_g1_i15,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^71-138^E:1.8e-22",NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i9,DN11648_c0_g1,RPGF4_RAT,Rap guanine nucleotide exchange factor 4,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0016323^cellular_component^basolateral plasma membrane,GO:0005903^cellular_component^brush border,GO:0005929^cellular_component^cilium,.,NA,NA,NA,NA,.,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN11648_c0_g1_i2,DN11648_c0_g1,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,RPGF4_HUMAN,Rap guanine nucleotide exchange factor 4,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,GO:0005829^cellular_component^cytosol,GO:0098686^cellular_component^hippocampal mossy fiber to CA3 synapse,GO:0016020^cellular_component^membrane,GO:0005886^cellular_component^plasma membrane,GO:0030552^molecular_function^cAMP binding,KEGG:hsa:11069`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^54-121^E:8.7e-22",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^211-290^E:3.7e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^332-437^E:1.3e-13,PF00617.19^RasGEF^RasGEF domain^607-784^E:8.3e-52,NA,,
yes,AD,PGF,DN2935_c0_g1_i10,DN2935_c0_g1,PGFRB_CANLF,Platelet-derived growth factor receptor beta,PGFRB_MOUSE,Platelet-derived growth factor receptor beta,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,KEGG:mmu:18596`KO:K05089,COG0515^Serine Threonine protein kinase,PF13927.6^Ig_3^Immunoglobulin domain^114-191^E:7.6e-10,PF13895.6^Ig_2^Immunoglobulin domain^114-207^E:5.1e-11,PF07679.16^I-set^Immunoglobulin I-set domain^116-201^E:6.6e-09,PF00047.25^ig^Immunoglobulin domain^118-197^E:2.2e-07,PF07679.16^I-set^Immunoglobulin I-set domain^215-310^E:3.1e-09,,
yes,AD,PGF,DN2935_c0_g1_i2,DN2935_c0_g1,PGFRB_CANLF,Platelet-derived growth factor receptor beta,PGFRB_MOUSE,Platelet-derived growth factor receptor beta,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,KEGG:mmu:18596`KO:K05089,COG0515^Serine Threonine protein kinase,PF13927.6^Ig_3^Immunoglobulin domain^212-289^E:8.5e-10,PF13895.6^Ig_2^Immunoglobulin domain^212-305^E:5.8e-11,PF07679.16^I-set^Immunoglobulin I-set domain^214-299^E:7.4e-09,PF00047.25^ig^Immunoglobulin domain^216-295^E:2.5e-07,PF07679.16^I-set^Immunoglobulin I-set domain^313-408^E:3.5e-09,,
yes,AD,PGF,DN2935_c0_g1_i7,DN2935_c0_g1,PGFRB_CANLF,Platelet-derived growth factor receptor beta,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005887^cellular_component^integral component of plasma membrane,GO:0031226^cellular_component^intrinsic component of plasma membrane,.,NA,NA,NA,NA,KEGG:cfa:442985`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN50906_c0_g2_i1,DN50906_c0_g2,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN50906_c1_g1_i1,DN50906_c1_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN50906_c1_g2_i1,DN50906_c1_g2,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN50906_c2_g1_i1,DN50906_c2_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN50906_c5_g1_i1,DN50906_c5_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN7986_c0_g1_i2,DN7986_c0_g1,PGFRA_CHICK,Platelet-derived growth factor receptor alpha,PGFRA_CHICK,Platelet-derived growth factor receptor alpha,GO:0005929^cellular_component^cilium,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0005929^cellular_component^cilium,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,COG0515^Serine Threonine protein kinase,PF07679.16^I-set^Immunoglobulin I-set domain^222-305^E:6.4e-08,PF07679.16^I-set^Immunoglobulin I-set domain^328-409^E:2.8e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^594-948^E:7.4e-108,PF00069.25^Pkinase^Protein kinase domain^596-689^E:1.7e-12,PF00069.25^Pkinase^Protein kinase domain^778-946^E:9.1e-29,,
yes,AD,PGF,DN7986_c0_g1_i5,DN7986_c0_g1,PGFRA_CHICK,Platelet-derived growth factor receptor alpha,PGFRA_CHICK,Platelet-derived growth factor receptor alpha,GO:0005929^cellular_component^cilium,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,GO:0005929^cellular_component^cilium,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,COG0515^Serine Threonine protein kinase,PF07679.16^I-set^Immunoglobulin I-set domain^241-324^E:6.6e-08,PF07679.16^I-set^Immunoglobulin I-set domain^347-428^E:2.8e-06,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^613-967^E:7.7e-108,PF00069.25^Pkinase^Protein kinase domain^615-708^E:1.7e-12,PF00069.25^Pkinase^Protein kinase domain^797-965^E:9.3e-29,,
yes,AD,PGF,DN1973_c0_g2_i4,DN1973_c0_g2,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^112-179^E:3.6e-15",PF00618.20^RasGEF_N^RasGEF N-terminal motif^361-461^E:9.8e-13,PF00617.19^RasGEF^RasGEF domain^637-813^E:3e-51,NA,NA,,
yes,AD,PGF,DN1973_c0_g2_i6,DN1973_c0_g2,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^112-179^E:3.4e-15",PF00618.20^RasGEF_N^RasGEF N-terminal motif^319-419^E:9.1e-13,PF00617.19^RasGEF^RasGEF domain^595-771^E:2.7e-51,NA,NA,,
yes,AD,PGF,DN1973_c0_g2_i2,DN1973_c0_g2,RPGF5_HUMAN,Rap guanine nucleotide exchange factor 5,RPGF5_HUMAN,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:hsa:9771`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00618.20^RasGEF_N^RasGEF N-terminal motif^67-167^E:5.3e-13,PF00617.19^RasGEF^RasGEF domain^343-519^E:1.4e-51,NA,NA,NA,,
yes,AD,PGF,DN1973_c0_g2_i1,DN1973_c0_g2,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^112-179^E:3.4e-15",PF00618.20^RasGEF_N^RasGEF N-terminal motif^319-419^E:9.1e-13,PF00617.19^RasGEF^RasGEF domain^595-771^E:2.7e-51,NA,NA,,
yes,AD,PGF,DN1973_c0_g2_i5,DN1973_c0_g2,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^112-179^E:3.6e-15",PF00618.20^RasGEF_N^RasGEF N-terminal motif^361-461^E:9.8e-13,PF00617.19^RasGEF^RasGEF domain^637-813^E:3e-51,NA,NA,,
yes,AD,PGF,DN1973_c0_g2_i3,DN1973_c0_g2,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,PF00618.20^RasGEF_N^RasGEF N-terminal motif^98-198^E:5.8e-13,PF00617.19^RasGEF^RasGEF domain^374-550^E:1.6e-51,NA,NA,NA,,
yes,AD,PGF,DN58738_c0_g1_i1,DN58738_c0_g1,RPGF2_RAT,Rap guanine nucleotide exchange factor 2,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005770^cellular_component^late endosome,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,.,NA,NA,NA,NA,KEGG:rno:310533`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN58738_c0_g1_i2,DN58738_c0_g1,RPGF2_RAT,Rap guanine nucleotide exchange factor 2,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005770^cellular_component^late endosome,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,.,NA,NA,NA,NA,KEGG:rno:310533`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN57978_c0_g1_i2,DN57978_c0_g1,RPGF3_MOUSE,Rap guanine nucleotide exchange factor 3,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0043679^cellular_component^axon terminus,GO:0009925^cellular_component^basal plasma membrane,GO:1990794^cellular_component^basolateral part of cell,GO:0031526^cellular_component^brush border membrane,.,NA,NA,NA,NA,KEGG:mmu:223864`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN32617_c0_g1_i1,DN32617_c0_g1,PGFRA_TAKRU,Platelet-derived growth factor receptor alpha,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005018^molecular_function^platelet-derived growth factor alpha-receptor activity,GO:0006935^biological_process^chemotaxis,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN3240_c0_g1_i5,DN3240_c0_g1,RPGFL_HUMAN,Rap guanine nucleotide exchange factor-like 1,.,NA,GO:0016020^cellular_component^membrane,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0007399^biological_process^nervous system development,GO:0007264^biological_process^small GTPase mediated signal transduction,.,NA,NA,NA,NA,KEGG:hsa:51195,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i7,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i12,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,PF00617.19^RasGEF^RasGEF domain^61-230^E:1.5e-53,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i13,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i17,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i10,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,PF00618.20^RasGEF_N^RasGEF N-terminal motif^74-122^E:4.4e-10,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i3,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,PF00617.19^RasGEF^RasGEF domain^83-252^E:1.8e-53,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i1,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i2,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,PF00617.19^RasGEF^RasGEF domain^61-230^E:1.5e-53,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i11,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g1_i6,DN9030_c0_g1,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9030_c0_g2_i1,DN9030_c0_g2,RPGF1_HUMAN,Rap guanine nucleotide exchange factor 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005769^cellular_component^early endosome,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0030670^cellular_component^phagocytic vesicle membrane,.,NA,NA,NA,NA,KEGG:hsa:2889`KO:K06277,ENOG410XP7D^Rap guanine nucleotide exchange factor (GEF) 1,.,NA,NA,NA,NA,,
no,AD,PGF,DN7282_c0_g2_i1,DN7282_c0_g2,HCFC1_MESAU,Host cell factor 1,RPGFL_HUMAN,Rap guanine nucleotide exchange factor-like 1,GO:0005737^cellular_component^cytoplasm,GO:0000123^cellular_component^histone acetyltransferase complex,GO:0071339^cellular_component^MLL1 complex,GO:0043025^cellular_component^neuronal cell body,GO:0005634^cellular_component^nucleus,GO:0016020^cellular_component^membrane,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0007399^biological_process^nervous system development,GO:0007264^biological_process^small GTPase mediated signal transduction,KEGG:hsa:51195,ENOG410XPX9^rap guanine nucleotide exchange factor,PF13854.6^Kelch_5^Kelch motif^31-69^E:4.6e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^34-71^E:1.3e-05",PF01344.25^Kelch_1^Kelch motif^34-71^E:6e-06,PF01344.25^Kelch_1^Kelch motif^256-310^E:1.8e-05,"PF13415.6^Kelch_3^Galactose oxidase, central domain^266-332^E:7.1e-06",,
no,AD,PGF,DN7282_c0_g2_i2,DN7282_c0_g2,HCFC1_MESAU,Host cell factor 1,RPGFL_HUMAN,Rap guanine nucleotide exchange factor-like 1,GO:0005737^cellular_component^cytoplasm,GO:0000123^cellular_component^histone acetyltransferase complex,GO:0071339^cellular_component^MLL1 complex,GO:0043025^cellular_component^neuronal cell body,GO:0005634^cellular_component^nucleus,GO:0016020^cellular_component^membrane,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0007399^biological_process^nervous system development,GO:0007264^biological_process^small GTPase mediated signal transduction,KEGG:hsa:51195,ENOG410XPX9^rap guanine nucleotide exchange factor,PF13854.6^Kelch_5^Kelch motif^31-69^E:4.6e-05,"PF13418.6^Kelch_4^Galactose oxidase, central domain^34-71^E:1.3e-05",PF01344.25^Kelch_1^Kelch motif^34-71^E:6e-06,PF01344.25^Kelch_1^Kelch motif^256-310^E:1.8e-05,"PF13415.6^Kelch_3^Galactose oxidase, central domain^266-332^E:7.1e-06",,
yes,AD,PGF,DN34815_c0_g1_i3,DN34815_c0_g1,PGFRB_HUMAN,Platelet-derived growth factor receptor beta,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005925^cellular_component^focal adhesion,.,NA,NA,NA,NA,KEGG:hsa:5159`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN34815_c0_g1_i4,DN34815_c0_g1,PGFRB_HUMAN,Platelet-derived growth factor receptor beta,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005925^cellular_component^focal adhesion,.,NA,NA,NA,NA,KEGG:hsa:5159`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN34815_c0_g1_i1,DN34815_c0_g1,PGFRB_HUMAN,Platelet-derived growth factor receptor beta,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005925^cellular_component^focal adhesion,.,NA,NA,NA,NA,KEGG:hsa:5159`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN67038_c0_g1_i2,DN67038_c0_g1,PGFRL_HUMAN,Platelet-derived growth factor receptor-like protein,PGFRL_HUMAN,Platelet-derived growth factor receptor-like protein,GO:0005576^cellular_component^extracellular region,GO:0004992^molecular_function^platelet activating factor receptor activity,GO:0005019^molecular_function^platelet-derived growth factor beta-receptor activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0004992^molecular_function^platelet activating factor receptor activity,GO:0005019^molecular_function^platelet-derived growth factor beta-receptor activity,NA,NA,KEGG:hsa:5157,COG0515^Serine Threonine protein kinase,PF13927.6^Ig_3^Immunoglobulin domain^297-387^E:3.1e-08,PF07679.16^I-set^Immunoglobulin I-set domain^307-399^E:8.7e-07,PF00047.25^ig^Immunoglobulin domain^319-395^E:1.4e-05,NA,NA,,
yes,AD,PGF,DN67038_c0_g1_i1,DN67038_c0_g1,PGFRL_MACFA,Platelet-derived growth factor receptor-like protein,PGFRL_HUMAN,Platelet-derived growth factor receptor-like protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0004992^molecular_function^platelet activating factor receptor activity,GO:0005019^molecular_function^platelet-derived growth factor beta-receptor activity,NA,NA,KEGG:hsa:5157,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN67038_c0_g1_i3,DN67038_c0_g1,PGFRL_MOUSE,Platelet-derived growth factor receptor-like protein,PGFRL_HUMAN,Platelet-derived growth factor receptor-like protein,GO:0005576^cellular_component^extracellular region,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0004992^molecular_function^platelet activating factor receptor activity,GO:0005019^molecular_function^platelet-derived growth factor beta-receptor activity,NA,NA,KEGG:hsa:5157,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN94830_c0_g1_i1,DN94830_c0_g1,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,.,NA,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN39824_c0_g1_i1,DN39824_c0_g1,PGFRA_TAKRU,Platelet-derived growth factor receptor alpha,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0005018^molecular_function^platelet-derived growth factor alpha-receptor activity,GO:0006935^biological_process^chemotaxis,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i1,DN2238_c1_g1,RPGF3_HUMAN,Rap guanine nucleotide exchange factor 3,.,NA,GO:0012505^cellular_component^endomembrane system,GO:0070062^cellular_component^extracellular exosome,GO:0030175^cellular_component^filopodium,GO:0030027^cellular_component^lamellipodium,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:10411`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i12,DN2238_c1_g1,RPGF3_HUMAN,Rap guanine nucleotide exchange factor 3,.,NA,GO:0012505^cellular_component^endomembrane system,GO:0070062^cellular_component^extracellular exosome,GO:0030175^cellular_component^filopodium,GO:0030027^cellular_component^lamellipodium,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:10411`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i14,DN2238_c1_g1,RPGF3_RAT,Rap guanine nucleotide exchange factor 3,RPGF3_HUMAN,Rap guanine nucleotide exchange factor 3,GO:0045177^cellular_component^apical part of cell,GO:0043679^cellular_component^axon terminus,GO:0009925^cellular_component^basal plasma membrane,GO:1990794^cellular_component^basolateral part of cell,GO:0031526^cellular_component^brush border membrane,GO:0012505^cellular_component^endomembrane system,GO:0070062^cellular_component^extracellular exosome,GO:0030175^cellular_component^filopodium,GO:0030027^cellular_component^lamellipodium,GO:0016020^cellular_component^membrane,KEGG:hsa:10411`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,"PF00610.21^DEP^Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)^171-239^E:6.6e-20",PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^325-404^E:2.2e-16,PF00618.20^RasGEF_N^RasGEF N-terminal motif^444-499^E:1.4e-07,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i4,DN2238_c1_g1,RPGF3_RAT,Rap guanine nucleotide exchange factor 3,.,NA,GO:0045177^cellular_component^apical part of cell,GO:0043679^cellular_component^axon terminus,GO:0009925^cellular_component^basal plasma membrane,GO:1990794^cellular_component^basolateral part of cell,GO:0031526^cellular_component^brush border membrane,.,NA,NA,NA,NA,KEGG:rno:59326`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i6,DN2238_c1_g1,RPGF3_HUMAN,Rap guanine nucleotide exchange factor 3,.,NA,GO:0012505^cellular_component^endomembrane system,GO:0070062^cellular_component^extracellular exosome,GO:0030175^cellular_component^filopodium,GO:0030027^cellular_component^lamellipodium,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:10411`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN2238_c1_g1_i13,DN2238_c1_g1,RPGF3_HUMAN,Rap guanine nucleotide exchange factor 3,.,NA,GO:0012505^cellular_component^endomembrane system,GO:0070062^cellular_component^extracellular exosome,GO:0030175^cellular_component^filopodium,GO:0030027^cellular_component^lamellipodium,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:10411`KO:K08014,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN9350_c0_g1_i3,DN9350_c0_g1,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:hsa:9693`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00618.20^RasGEF_N^RasGEF N-terminal motif^476-562^E:2.4e-11,PF00595.24^PDZ^PDZ domain^607-667^E:7e-10,PF17820.1^PDZ_6^PDZ domain^617-668^E:3.1e-09,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^812-895^E:6.7e-11,PF00617.19^RasGEF^RasGEF domain^925-1103^E:2.3e-52,,
yes,AD,PGF,DN9350_c0_g1_i1,DN9350_c0_g1,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:hsa:9693`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00618.20^RasGEF_N^RasGEF N-terminal motif^271-357^E:2.1e-11,PF00595.24^PDZ^PDZ domain^402-462^E:6.1e-10,PF17820.1^PDZ_6^PDZ domain^412-463^E:2.7e-09,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^607-690^E:5.8e-11,PF00617.19^RasGEF^RasGEF domain^720-898^E:1.9e-52,,
yes,AD,PGF,DN9350_c0_g1_i2,DN9350_c0_g1,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,RPGF2_HUMAN,Rap guanine nucleotide exchange factor 2,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016324^cellular_component^apical plasma membrane,GO:0005923^cellular_component^bicellular tight junction,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:hsa:9693`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00618.20^RasGEF_N^RasGEF N-terminal motif^476-562^E:2.4e-11,PF00595.24^PDZ^PDZ domain^607-667^E:7e-10,PF17820.1^PDZ_6^PDZ domain^617-668^E:3.1e-09,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^812-895^E:6.8e-11,PF00617.19^RasGEF^RasGEF domain^925-1103^E:2.3e-52,,
yes,AD,PGF,DN9350_c0_g2_i12,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^316-394^E:1.5e-06,PF00618.20^RasGEF_N^RasGEF N-terminal motif^429-515^E:1.1e-12,PF00595.24^PDZ^PDZ domain^543-620^E:3.6e-11,PF17820.1^PDZ_6^PDZ domain^570-621^E:8.5e-11,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^764-847^E:4.4e-12,,
yes,AD,PGF,DN9350_c0_g2_i9,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^215-293^E:1.4e-06,PF00618.20^RasGEF_N^RasGEF N-terminal motif^328-414^E:1e-12,PF00595.24^PDZ^PDZ domain^442-519^E:3.3e-11,PF17820.1^PDZ_6^PDZ domain^469-520^E:7.9e-11,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^663-746^E:4.1e-12,,
yes,AD,PGF,DN9350_c0_g2_i6,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN9350_c0_g2_i11,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN9350_c0_g2_i14,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),PF00027.29^cNMP_binding^Cyclic nucleotide-binding domain^188-266^E:1.3e-06,PF00618.20^RasGEF_N^RasGEF N-terminal motif^301-387^E:1e-12,PF00595.24^PDZ^PDZ domain^415-492^E:3.2e-11,PF17820.1^PDZ_6^PDZ domain^442-493^E:7.7e-11,PF00788.23^RA^Ras association (RalGDS/AF-6) domain^636-719^E:4e-12,,
yes,AD,PGF,DN9350_c0_g2_i2,DN9350_c0_g2,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN9350_c0_g3_i1,DN9350_c0_g3,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,RPGF6_HUMAN,Rap guanine nucleotide exchange factor 6,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,GO:0016324^cellular_component^apical plasma membrane,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0030139^cellular_component^endocytic vesicle,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:51735`KO:K08020,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN89217_c0_g1_i1,DN89217_c0_g1,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,.,NA,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN105683_c0_g1_i1,DN105683_c0_g1,PGFRA_CHICK,Platelet-derived growth factor receptor alpha,.,NA,GO:0005929^cellular_component^cilium,GO:0005794^cellular_component^Golgi apparatus,GO:0005887^cellular_component^integral component of plasma membrane,GO:0043235^cellular_component^receptor complex,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,.,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN105781_c0_g1_i2,DN105781_c0_g1,RPGF4_MOUSE,Rap guanine nucleotide exchange factor 4,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0030424^cellular_component^axon,GO:0016323^cellular_component^basolateral plasma membrane,GO:0005903^cellular_component^brush border,GO:0005929^cellular_component^cilium,.,NA,NA,NA,NA,KEGG:mmu:56508`KO:K04351,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN110539_c0_g1_i1,DN110539_c0_g1,RPGFL_PONPY,Rap guanine nucleotide exchange factor-like 1,.,NA,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007264^biological_process^small GTPase mediated signal transduction,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,PGF,DN130940_c0_g1_i1,DN130940_c0_g1,RPGF5_MOUSE,Rap guanine nucleotide exchange factor 5,.,NA,GO:0016604^cellular_component^nuclear body,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030742^molecular_function^GTP-dependent protein binding,GO:0017034^molecular_function^Rap guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:217944`KO:K08019,ENOG410XPX9^rap guanine nucleotide exchange factor,.,NA,NA,NA,NA,,
yes,AD,PGF,DN268906_c0_g1_i1,DN268906_c0_g1,PGFRB_MOUSE,Platelet-derived growth factor receptor beta,.,NA,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,.,NA,NA,NA,NA,KEGG:mmu:18596`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PGF,DN289457_c0_g1_i1,DN289457_c0_g1,RPGF2_BOVIN,Rap guanine nucleotide exchange factor 2,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005770^cellular_component^late endosome,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,.,NA,NA,NA,NA,KEGG:bta:100139484`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN439203_c0_g1_i1,DN439203_c0_g1,RPGF2_RAT,Rap guanine nucleotide exchange factor 2,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005770^cellular_component^late endosome,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,.,NA,NA,NA,NA,KEGG:rno:310533`KO:K08018,ENOG410XS6B^Rap guanine nucleotide exchange factor (GEF),.,NA,NA,NA,NA,,
yes,AD,PGF,DN408585_c0_g1_i1,DN408585_c0_g1,PGFRB_MOUSE,Platelet-derived growth factor receptor beta,PGFRB_MOUSE,Platelet-derived growth factor receptor beta,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,GO:0016324^cellular_component^apical plasma membrane,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005794^cellular_component^Golgi apparatus,KEGG:mmu:18596`KO:K05089,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN12044_c0_g1_i2,DN12044_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN12044_c0_g3_i1,DN12044_c0_g3,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN12044_c0_g4_i1,DN12044_c0_g4,PIAS2_MOUSE,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016604^cellular_component^nuclear body,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,.,NA,NA,NA,NA,KEGG:mmu:17344`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN54004_c0_g1_i2,DN54004_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN57731_c0_g1_i3,DN57731_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN57731_c0_g1_i2,DN57731_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN57731_c0_g1_i1,DN57731_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN57731_c0_g2_i1,DN57731_c0_g2,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN6102_c0_g1_i6,DN6102_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN91717_c0_g1_i2,DN91717_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN91717_c0_g1_i1,DN91717_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN23490_c0_g1_i1,DN23490_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN23490_c0_g2_i2,DN23490_c0_g2,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN23490_c0_g2_i1,DN23490_c0_g2,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i3,DN2260_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i5,DN2260_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,PF14324.6^PINIT^PINIT domain^146-297^E:9.7e-35,PF02891.20^zf-MIZ^MIZ/SP-RING zinc finger^342-390^E:1.2e-21,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i10,DN2260_c0_g1,PIAS2_RAT,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:83422`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i2,DN2260_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,.,NA,NA,NA,NA,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i4,DN2260_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,PF14324.6^PINIT^PINIT domain^146-297^E:7.7e-35,PF02891.20^zf-MIZ^MIZ/SP-RING zinc finger^342-390^E:1e-21,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i9,DN2260_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,PIAS2_MOUSE,E3 SUMO-protein ligase PIAS2,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0016604^cellular_component^nuclear body,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,KEGG:mmu:17344`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
yes,AD,PIAS2,DN2260_c0_g1_i1,DN2260_c0_g1,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,PIAS2_HUMAN,E3 SUMO-protein ligase PIAS2,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0050681^molecular_function^androgen receptor binding,KEGG:hsa:9063`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,PF02891.20^zf-MIZ^MIZ/SP-RING zinc finger^3-43^E:3.3e-19,NA,NA,NA,NA,,
yes,AD,PIAS2,DN28135_c0_g1_i1,DN28135_c0_g1,PIAS2_MOUSE,E3 SUMO-protein ligase PIAS2,.,NA,GO:0016604^cellular_component^nuclear body,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,.,NA,NA,NA,NA,KEGG:mmu:17344`KO:K16063,ENOG410XQ2E^Protein inhibitor of activated STAT,.,NA,NA,NA,NA,,
no,AD,PKR,DN4597_c0_g1_i5,DN4597_c0_g1,PKR1_BOVIN,Prokineticin receptor 1,PKR1_BOVIN,Prokineticin receptor 1,GO:0005887^cellular_component^integral component of plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,GO:0005887^cellular_component^integral component of plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,GO:0007186^biological_process^G protein-coupled receptor signaling pathway,KEGG:bta:281800`KO:K08379,ENOG410XRW9^Receptor,PF10320.9^7TM_GPCR_Srsx^Serpentine type 7TM GPCR chemoreceptor Srsx^79-353^E:0.00012,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^83-345^E:9.5e-47,NA,NA,NA,,
no,AD,PKR,DN4597_c0_g1_i4,DN4597_c0_g1,PKR2_HUMAN,Prokineticin receptor 2,PKR2_HUMAN,Prokineticin receptor 2,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,KEGG:hsa:128674`KO:K08380,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^2-168^E:2.3e-18,NA,NA,NA,NA,,
no,AD,PKR,DN4597_c0_g1_i3,DN4597_c0_g1,PKR2_HUMAN,Prokineticin receptor 2,PKR2_HUMAN,Prokineticin receptor 2,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,KEGG:hsa:128674`KO:K08380,ENOG410XRW9^Receptor,PF00001.21^7tm_1^7 transmembrane receptor (rhodopsin family)^2-168^E:2.3e-18,NA,NA,NA,NA,,
no,AD,PKR,DN4597_c0_g1_i1,DN4597_c0_g1,PKR2_HUMAN,Prokineticin receptor 2,.,NA,GO:0005887^cellular_component^integral component of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0004930^molecular_function^G protein-coupled receptor activity,GO:0004983^molecular_function^neuropeptide Y receptor activity,GO:0007623^biological_process^circadian rhythm,.,NA,NA,NA,NA,KEGG:hsa:128674`KO:K08380,ENOG410XRW9^Receptor,.,NA,NA,NA,NA,,
no,AD,PKR,DN5912_c0_g1_i3,DN5912_c0_g1,PKRI1_CHICK,PRKR-interacting protein 1 homolog,PKRI1_CHICK,PRKR-interacting protein 1 homolog,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,KEGG:gga:417508,ENOG4111T1J^PRKR interacting protein 1 (IL11 inducible),PF06658.12^DUF1168^Protein of unknown function (DUF1168)^58-192^E:2.7e-47,NA,NA,NA,NA,,
no,AD,PKR,DN5912_c0_g2_i2,DN5912_c0_g2,PKRI1_CHICK,PRKR-interacting protein 1 homolog,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:417508,ENOG4111T1J^PRKR interacting protein 1 (IL11 inducible),.,NA,NA,NA,NA,,
no,AD,PKR,DN5912_c0_g2_i5,DN5912_c0_g2,PKRI1_CHICK,PRKR-interacting protein 1 homolog,PKRI1_BOVIN,PRKR-interacting protein 1,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,KEGG:bta:780786,ENOG4111T1J^PRKR interacting protein 1 (IL11 inducible),PF06658.12^DUF1168^Protein of unknown function (DUF1168)^58-86^E:5e-05,NA,NA,NA,NA,,
no,AD,PKR,DN5912_c0_g2_i1,DN5912_c0_g2,PKRI1_CHICK,PRKR-interacting protein 1 homolog,PKRI1_BOVIN,PRKR-interacting protein 1,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,KEGG:bta:780786,ENOG4111T1J^PRKR interacting protein 1 (IL11 inducible),PF06658.12^DUF1168^Protein of unknown function (DUF1168)^58-86^E:5e-05,NA,NA,NA,NA,,
no,AD,PKR,DN5912_c0_g3_i1,DN5912_c0_g3,PKRI1_CHICK,PRKR-interacting protein 1 homolog,.,NA,GO:0005730^cellular_component^nucleolus,GO:0005681^cellular_component^spliceosomal complex,GO:0003725^molecular_function^double-stranded RNA binding,GO:0019901^molecular_function^protein kinase binding,GO:0004860^molecular_function^protein kinase inhibitor activity,.,NA,NA,NA,NA,KEGG:gga:417508,ENOG4111T1J^PRKR interacting protein 1 (IL11 inducible),.,NA,NA,NA,NA,,
yes,AD,RNF135,DN22_c0_g1_i6,DN22_c0_g1,MIRO1_CHICK,Mitochondrial Rho GTPase 1,RN135_HUMAN,E3 ubiquitin-protein ligase RNF135,GO:0031307^cellular_component^integral component of mitochondrial outer membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0019725^biological_process^cellular homeostasis,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0042802^molecular_function^identical protein binding,GO:0046872^molecular_function^metal ion binding,GO:0043021^molecular_function^ribonucleoprotein complex binding,KEGG:hsa:84282`KO:K16272,ENOG4111G04^tripartite motif containing,PF00622.28^SPRY^SPRY domain^32-140^E:1.4e-11,NA,NA,NA,NA,,
yes,AD,RNF135,DN22_c0_g1_i12,DN22_c0_g1,MIRO1_CHICK,Mitochondrial Rho GTPase 1,RN135_HUMAN,E3 ubiquitin-protein ligase RNF135,GO:0031307^cellular_component^integral component of mitochondrial outer membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0019725^biological_process^cellular homeostasis,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0042802^molecular_function^identical protein binding,GO:0046872^molecular_function^metal ion binding,GO:0043021^molecular_function^ribonucleoprotein complex binding,KEGG:hsa:84282`KO:K16272,ENOG4111G04^tripartite motif containing,PF00622.28^SPRY^SPRY domain^32-140^E:1.4e-11,NA,NA,NA,NA,,
yes,AD,RNF135,DN22_c0_g1_i4,DN22_c0_g1,MIRO1_CHICK,Mitochondrial Rho GTPase 1,RN135_HUMAN,E3 ubiquitin-protein ligase RNF135,GO:0031307^cellular_component^integral component of mitochondrial outer membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0019725^biological_process^cellular homeostasis,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0042802^molecular_function^identical protein binding,GO:0046872^molecular_function^metal ion binding,GO:0043021^molecular_function^ribonucleoprotein complex binding,KEGG:hsa:84282`KO:K16272,ENOG4111G04^tripartite motif containing,PF00622.28^SPRY^SPRY domain^32-140^E:1.4e-11,NA,NA,NA,NA,,
yes,AD,RNF135,DN22_c0_g1_i3,DN22_c0_g1,MIRO1_CHICK,Mitochondrial Rho GTPase 1,RN135_HUMAN,E3 ubiquitin-protein ligase RNF135,GO:0031307^cellular_component^integral component of mitochondrial outer membrane,GO:0005509^molecular_function^calcium ion binding,GO:0005525^molecular_function^GTP binding,GO:0003924^molecular_function^GTPase activity,GO:0019725^biological_process^cellular homeostasis,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0042802^molecular_function^identical protein binding,GO:0046872^molecular_function^metal ion binding,GO:0043021^molecular_function^ribonucleoprotein complex binding,KEGG:hsa:84282`KO:K16272,ENOG4111G04^tripartite motif containing,PF00622.28^SPRY^SPRY domain^32-140^E:1.4e-11,NA,NA,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i3,DN1920_c0_g1,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,.,NA,NA,NA,NA,KEGG:bta:506415`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,.,NA,NA,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i9,DN1920_c0_g1,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,KEGG:bta:506415`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,PF13353.6^Fer4_12^4Fe-4S single cluster domain^85-175^E:4.2e-08,PF04055.21^Radical_SAM^Radical SAM superfamily^87-217^E:4.5e-16,PF13394.6^Fer4_14^4Fe-4S single cluster domain^88-171^E:2e-06,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i10,DN1920_c0_g1,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,KEGG:bta:506415`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,PF13353.6^Fer4_12^4Fe-4S single cluster domain^85-175^E:2.6e-08,PF04055.21^Radical_SAM^Radical SAM superfamily^87-217^E:3.3e-16,PF13394.6^Fer4_14^4Fe-4S single cluster domain^88-171^E:1.3e-06,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i6,DN1920_c0_g1,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,KEGG:bta:506415`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,.,NA,NA,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i1,DN1920_c0_g1,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,RSAD2_BOVIN,Radical S-adenosyl methionine domain-containing protein 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0001650^cellular_component^fibrillar center,GO:0005811^cellular_component^lipid droplet,GO:0005743^cellular_component^mitochondrial inner membrane,KEGG:bta:506415`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,PF13353.6^Fer4_12^4Fe-4S single cluster domain^85-171^E:3.6e-08,PF04055.21^Radical_SAM^Radical SAM superfamily^87-179^E:1.4e-10,PF13394.6^Fer4_14^4Fe-4S single cluster domain^88-169^E:1.1e-06,NA,NA,,
yes,AD,RSAD2,DN1920_c0_g1_i11,DN1920_c0_g1,RSAD2_PIG,Radical S-adenosyl methionine domain-containing protein 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005811^cellular_component^lipid droplet,"GO:0051539^molecular_function^4 iron, 4 sulfur cluster binding",GO:0003824^molecular_function^catalytic activity,.,NA,NA,NA,NA,KEGG:ssc:396752`KO:K15045,ENOG410XQM5^Radical S-adenosyl methionine domain containing 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN88470_c4_g1_i1,DN88470_c4_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN28741_c0_g1_i3,DN28741_c0_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN12_c0_g1_i4,DN12_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^64-176^E:1.2e-21,NA,NA,NA,NA,,
no,AD,SAT,DN12_c0_g1_i1,DN12_c0_g1,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^1-350^E:2e-15,PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^2-430^E:1.6e-25,PF13476.6^AAA_23^AAA domain^6-344^E:8.1e-09,"PF13304.6^AAA_21^AAA domain, putative AbiEii toxin, Type IV TA system^28-55^E:2e-06",PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^530-642^E:5.9e-21,,
no,AD,SAT,DN12_c0_g1_i5,DN12_c0_g1,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^64-176^E:5.6e-21,PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^383-730^E:1.7e-28,NA,NA,NA,,
no,AD,SAT,DN12_c0_g1_i2,DN12_c0_g1,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,SMC3_RAT,Structural maintenance of chromosomes protein 3,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^1-349^E:5.4e-15,PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^2-133^E:1e-34,PF13476.6^AAA_23^AAA domain^6-344^E:1.1e-09,"PF13304.6^AAA_21^AAA domain, putative AbiEii toxin, Type IV TA system^28-57^E:7.4e-07",NA,,
no,AD,SAT,DN12_c0_g1_i3,DN12_c0_g1,SMC3_PONAB,Structural maintenance of chromosomes protein 3,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^1-350^E:7.3e-16,PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^2-1196^E:3.9e-63,PF13476.6^AAA_23^AAA domain^6-344^E:8.2e-09,"PF13304.6^AAA_21^AAA domain, putative AbiEii toxin, Type IV TA system^28-55^E:3.4e-06",PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^530-642^E:1.1e-20,,
no,AD,SAT,DN12_c0_g1_i6,DN12_c0_g1,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,SMC3_MOUSE,Structural maintenance of chromosomes protein 3,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000800^cellular_component^lateral element,KEGG:mmu:13006`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^79-427^E:2.3e-32,NA,NA,NA,NA,,
no,AD,SAT,DN94_c0_g1_i6,DN94_c0_g1,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:8924`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^509-562^E:9.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^549-577^E:6.1e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^565-608^E:6.1e-14,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^619-668^E:8e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^655-680^E:0.00011,,
no,AD,SAT,DN94_c0_g1_i7,DN94_c0_g1,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:8924`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^246-299^E:9.2e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^286-314^E:5.7e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^302-345^E:5.7e-14,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^356-405^E:7.5e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^392-417^E:0.00011,,
no,AD,SAT,DN94_c0_g1_i9,DN94_c0_g1,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:8924`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^514-567^E:9.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^554-582^E:6.1e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^570-613^E:6.1e-14,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^624-673^E:8e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^660-685^E:0.00011,,
no,AD,SAT,DN94_c0_g1_i1,DN94_c0_g1,HERC2_MOUSE,E3 ubiquitin-protein ligase HERC2,.,NA,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005634^cellular_component^nucleus,GO:0032183^molecular_function^SUMO binding,.,NA,NA,NA,NA,KEGG:mmu:15204`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN40_c0_g1_i1,DN40_c0_g1,SRGEF_MOUSE,Secretion-regulating guanine nucleotide exchange factor,.,NA,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:27414`KO:K15421,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN40_c0_g1_i5,DN40_c0_g1,SRGEF_MOUSE,Secretion-regulating guanine nucleotide exchange factor,.,NA,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:27414`KO:K15421,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN40_c0_g1_i4,DN40_c0_g1,SRGEF_MOUSE,Secretion-regulating guanine nucleotide exchange factor,.,NA,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:27414`KO:K15421,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN40_c0_g2_i1,DN40_c0_g2,SRGEF_MOUSE,Secretion-regulating guanine nucleotide exchange factor,SRGEF_MOUSE,Secretion-regulating guanine nucleotide exchange factor,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:27414`KO:K15421,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^17-65^E:2.7e-09,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^52-81^E:3.7e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^69-116^E:2.2e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^104-133^E:7.8e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^121-168^E:1.7e-09,,
no,AD,SAT,DN27912_c0_g1_i1,DN27912_c0_g1,KCTD8_HUMAN,BTB/POZ domain-containing protein KCTD8,KCTD8_HUMAN,BTB/POZ domain-containing protein KCTD8,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,KEGG:hsa:386617`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i5,DN11687_c0_g1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^42-130^E:4.1e-17,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i7,DN11687_c0_g1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^32-120^E:3.8e-17,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i3,DN11687_c0_g1,KCTD1_BOVIN,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^149-237^E:7.8e-17,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i4,DN11687_c0_g1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^32-120^E:3.8e-17,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i6,DN11687_c0_g1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^32-120^E:3.8e-17,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i1,DN11687_c0_g1,KCTD1_BOVIN,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN11687_c0_g1_i2,DN11687_c0_g1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,KCTD1_MOUSE,BTB/POZ domain-containing protein KCTD1,GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",GO:0005634^cellular_component^nucleus,GO:0042802^molecular_function^identical protein binding,GO:0003714^molecular_function^transcription corepressor activity,GO:0008134^molecular_function^transcription factor binding,"GO:0045892^biological_process^negative regulation of transcription, DNA-templated",KEGG:mmu:106931`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^86-174^E:5.6e-17,NA,NA,NA,NA,,
no,AD,SAT,DN2934_c1_g2_i1,DN2934_c1_g2,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,PF16294.5^RSB_motif^RNSP1-SAP18 binding (RSB) motif^16-68^E:1.4e-22,NA,NA,NA,NA,,
no,AD,SAT,DN2934_c1_g2_i3,DN2934_c1_g2,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,PF16294.5^RSB_motif^RNSP1-SAP18 binding (RSB) motif^106-166^E:1.5e-23,NA,NA,NA,NA,,
no,AD,SAT,DN68745_c0_g1_i1,DN68745_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN2054_c1_g1_i4,DN2054_c1_g1,KCD12_HUMAN,BTB/POZ domain-containing protein KCTD12,KCD12_MOUSE,BTB/POZ domain-containing protein KCTD12,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:239217`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN2033_c0_g1_i2,DN2033_c0_g1,SAT2_HUMAN,Diamine acetyltransferase 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:112483`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN2033_c0_g1_i7,DN2033_c0_g1,SAT2_BOVIN,Diamine acetyltransferase 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:bta:359722`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN2033_c0_g1_i1,DN2033_c0_g1,SAT2_BOVIN,Diamine acetyltransferase 2,SAT2_HUMAN,Diamine acetyltransferase 2,GO:0005737^cellular_component^cytoplasm,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,KEGG:hsa:112483`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,PF00583.25^Acetyltransf_1^Acetyltransferase (GNAT) family^15-112^E:0.00041,NA,NA,NA,NA,,
no,AD,SAT,DN2033_c0_g1_i16,DN2033_c0_g1,SAT2_BOVIN,Diamine acetyltransferase 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:bta:359722`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN7845_c1_g1_i1,DN7845_c1_g1,SATT_BOVIN,Neutral amino acid transporter A,SATT_BOVIN,Neutral amino acid transporter A,GO:0005813^cellular_component^centrosome,GO:0016021^cellular_component^integral component of membrane,GO:0005882^cellular_component^intermediate filament,GO:0042470^cellular_component^melanosome,GO:0005254^molecular_function^chloride channel activity,GO:0005813^cellular_component^centrosome,GO:0016021^cellular_component^integral component of membrane,GO:0005882^cellular_component^intermediate filament,GO:0042470^cellular_component^melanosome,GO:0005254^molecular_function^chloride channel activity,KEGG:bta:326577`KO:K05615,COG1301^sodium dicarboxylate symporter,PF00375.18^SDF^Sodium:dicarboxylate symporter family^3-432^E:2.4e-119,NA,NA,NA,NA,,
no,AD,SAT,DN1128_c0_g1_i7,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-82^E:8.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^86-134^E:6.3e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-150^E:8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^137-187^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^190-255^E:1e-12,,
no,AD,SAT,DN1128_c0_g1_i3,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-82^E:8.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^86-134^E:6.3e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-150^E:8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^137-187^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^190-255^E:1e-12,,
no,AD,SAT,DN1128_c0_g1_i5,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^39-86^E:8.9e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^90-138^E:6.4e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^125-154^E:8.1e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^141-191^E:1.3e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^194-259^E:1e-12,,
no,AD,SAT,DN1128_c0_g1_i1,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-82^E:8.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^86-134^E:6.3e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-150^E:8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^137-187^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^190-255^E:1e-12,,
no,AD,SAT,DN1128_c0_g1_i2,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-82^E:8.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^86-134^E:6.3e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-150^E:8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^137-187^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^190-255^E:1e-12,,
no,AD,SAT,DN1128_c0_g1_i4,DN1128_c0_g1,RCC1_HUMAN,Regulator of chromosome condensation,RCC1_HUMAN,Regulator of chromosome condensation,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,GO:0000785^cellular_component^chromatin,GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005737^cellular_component^cytoplasm,GO:0000790^cellular_component^nuclear chromatin,GO:0031965^cellular_component^nuclear membrane,KEGG:hsa:1104`KO:K11493,.,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-82^E:8.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^86-134^E:6.3e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-150^E:8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^137-187^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^190-255^E:1e-12,,
no,AD,SAT,DN42608_c0_g1_i3,DN42608_c0_g1,KCTD8_HUMAN,BTB/POZ domain-containing protein KCTD8,KCTD8_HUMAN,BTB/POZ domain-containing protein KCTD8,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,KEGG:hsa:386617`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN92432_c0_g1_i1,DN92432_c0_g1,KCD16_HUMAN,BTB/POZ domain-containing protein KCTD16,.,NA,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0051260^biological_process^protein homooligomerization,NA,.,NA,NA,NA,NA,KEGG:hsa:57528`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i4,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^57-330^E:2.6e-67,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i6,DN15463_c0_g1,HMGC2_MOUSE,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^15-136^E:4.4e-36,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i13,DN15463_c0_g1,HMGC2_MOUSE,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^57-187^E:1.3e-22,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i15,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_DANRE,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:dre:571388`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^57-141^E:5.2e-10,PF00682.19^HMGL-like^HMGL-like^140-259^E:1.8e-34,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i1,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^27-157^E:7.4e-23,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i12,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",.,NA,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,.,NA,NA,NA,NA,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i7,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^57-274^E:1.4e-49,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i11,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:hsa:54511`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^27-300^E:1.9e-67,NA,NA,NA,NA,,
no,AD,SAT,DN15463_c0_g1_i10,DN15463_c0_g1,HMGC2_HUMAN,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",HMGC2_MOUSE,"3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic",GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016020^cellular_component^membrane,GO:0048471^cellular_component^perinuclear region of cytoplasm,KEGG:mmu:208982`KO:K01640,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^57-137^E:1.8e-10,NA,NA,NA,NA,,
no,AD,SAT,DN6073_c0_g1_i17,DN6073_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,.,NA,NA,NA,NA,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN83394_c0_g1_i1,DN83394_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN14750_c0_g1_i9,DN14750_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN14750_c0_g1_i1,DN14750_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN14750_c0_g1_i7,DN14750_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN47287_c0_g1_i3,DN47287_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,.,NA,NA,NA,NA,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN47287_c0_g1_i4,DN47287_c0_g1,IBTK_XENLA,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g1_i2,DN38192_c0_g1,HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,KEGG:mmu:67432`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^52-251^E:1.5e-37,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g1_i11,DN38192_c0_g1,HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,KEGG:mmu:67432`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^52-175^E:2.8e-19,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g1_i6,DN38192_c0_g1,HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,KEGG:mmu:67432`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^52-129^E:5.1e-07,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g1_i4,DN38192_c0_g1,HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,.,NA,NA,NA,NA,KEGG:hsa:112817`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g1_i9,DN38192_c0_g1,HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,KEGG:hsa:112817`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN38192_c0_g2_i1,DN38192_c0_g2,HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,KEGG:hsa:112817`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN13908_c0_g4_i1,DN13908_c0_g4,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN72781_c0_g1_i1,DN72781_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,.,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,.,NA,NA,NA,NA,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30009_c0_g1_i1,DN30009_c0_g1,SMC3_BOVIN,Structural maintenance of chromosomes protein 3,.,NA,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0016363^cellular_component^nuclear matrix,.,NA,NA,NA,NA,KEGG:bta:281729`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN63752_c0_g1_i1,DN63752_c0_g1,HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",.,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,.,NA,NA,NA,NA,KEGG:hsa:112817`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i11,DN8265_c0_g1,SMC5_CHICK,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i10,DN8265_c0_g1,SMC5_CHICK,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i9,DN8265_c0_g1,SMC5_CHICK,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i1,DN8265_c0_g1,SMC5_MOUSE,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,GO:0030054^cellular_component^cell junction,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,KEGG:mmu:226026`KO:K22803,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i4,DN8265_c0_g1,SMC5_CHICK,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8265_c0_g1_i2,DN8265_c0_g1,SMC5_CHICK,Structural maintenance of chromosomes protein 5,SMC5_CHICK,Structural maintenance of chromosomes protein 5,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,.,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13476.6^AAA_23^AAA domain^57-299^E:2.1e-09,NA,NA,NA,NA,,
no,AD,SAT,DN79069_c0_g1_i1,DN79069_c0_g1,SATB1_HUMAN,DNA-binding protein SATB1,.,NA,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:6304`KO:K23225,.,.,NA,NA,NA,NA,,
no,AD,SAT,DN17722_c0_g1_i1,DN17722_c0_g1,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,.,NA,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:22985`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN17722_c0_g1_i2,DN17722_c0_g1,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:22985`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN17722_c0_g1_i4,DN17722_c0_g1,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,.,NA,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:22985`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN2728_c0_g1_i1,DN2728_c0_g1,RCC2_HUMAN,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,.,NA,NA,NA,NA,KEGG:hsa:55920,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN2728_c0_g1_i4,DN2728_c0_g1,RCC2_MOUSE,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,.,NA,NA,NA,NA,KEGG:mmu:108911,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN2728_c0_g1_i3,DN2728_c0_g1,RCC2_MOUSE,Protein RCC2,RCC2_MOUSE,Protein RCC2,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,KEGG:mmu:108911,COG5184^regulator of chromosome condensation,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^73-94^E:4.6e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^81-130^E:1.7e-15,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^121-146^E:3.2e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^133-181^E:2.6e-12,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^185-258^E:8.3e-11,,
no,AD,SAT,DN2728_c0_g1_i2,DN2728_c0_g1,RCC2_MOUSE,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,.,NA,NA,NA,NA,KEGG:mmu:108911,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i2,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i9,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,NPL_CHICK,N-acetylneuraminate lyase,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^32-120^E:2.9e-16,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i5,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,NPL_CHICK,N-acetylneuraminate lyase,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i4,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i7,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i8,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,NPL_CHICK,N-acetylneuraminate lyase,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^1-107^E:3.8e-11,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i10,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i1,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,NPL_PONAB,N-acetylneuraminate lyase,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,KEGG:pon:100171523`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^17-89^E:7e-15,NA,NA,NA,NA,,
no,AD,SAT,DN8503_c0_g1_i6,DN8503_c0_g1,NPL_CHICK,N-acetylneuraminate lyase,NPL_CHICK,N-acetylneuraminate lyase,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^37-162^E:1.6e-15,NA,NA,NA,NA,,
no,AD,SAT,DN6794_c0_g1_i2,DN6794_c0_g1,KCD12_HUMAN,BTB/POZ domain-containing protein KCTD12,KCD12_HUMAN,BTB/POZ domain-containing protein KCTD12,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:115207`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^22-111^E:9.8e-15,NA,NA,NA,NA,,
no,AD,SAT,DN6794_c0_g3_i1,DN6794_c0_g3,KCD12_HUMAN,BTB/POZ domain-containing protein KCTD12,KCD12_HUMAN,BTB/POZ domain-containing protein KCTD12,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0042802^molecular_function^identical protein binding,GO:0003723^molecular_function^RNA binding,KEGG:hsa:115207`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^25-114^E:2.3e-15,NA,NA,NA,NA,,
no,AD,SAT,DN39680_c0_g1_i1,DN39680_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^49-119^E:9.8e-23,NA,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i3,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:79677`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^56-342^E:1.4e-09,PF13476.6^AAA_23^AAA domain^58-347^E:1.2e-14,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i2,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:79677`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^56-342^E:2.1e-09,PF13476.6^AAA_23^AAA domain^58-347^E:7.7e-15,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i9,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:79677`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^56-1060^E:2.1e-15,PF13175.6^AAA_15^AAA ATPase domain^56-342^E:1.8e-09,PF13476.6^AAA_23^AAA domain^58-347^E:1.4e-14,NA,NA,,
no,AD,SAT,DN290_c0_g1_i5,DN290_c0_g1,SMC6_MOUSE,Structural maintenance of chromosomes protein 6,.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:67241`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i11,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:79677`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),PF13175.6^AAA_15^AAA ATPase domain^56-342^E:2.1e-09,PF13476.6^AAA_23^AAA domain^58-347^E:7.7e-15,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i4,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:79677`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^56-1056^E:6e-15,PF13175.6^AAA_15^AAA ATPase domain^56-342^E:1.7e-09,PF13476.6^AAA_23^AAA domain^58-347^E:1.3e-14,NA,NA,,
no,AD,SAT,DN290_c0_g1_i1,DN290_c0_g1,SMC6_MOUSE,Structural maintenance of chromosomes protein 6,.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:mmu:67241`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN290_c0_g1_i8,DN290_c0_g1,SMC6_HUMAN,Structural maintenance of chromosomes protein 6,SMC6_XENLA,Structural maintenance of chromosomes protein 6,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0035061^cellular_component^interchromatin granule,GO:0005622^cellular_component^intracellular,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0016605^cellular_component^PML body,GO:0030915^cellular_component^Smc5-Smc6 complex,GO:0005524^molecular_function^ATP binding,GO:0090398^biological_process^cellular senescence,KEGG:xla:398986`KO:K22804,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN14345_c0_g1_i3,DN14345_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN14345_c0_g1_i2,DN14345_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN64066_c0_g2_i1,DN64066_c0_g2,CYGB1_ORYLA,Cytoglobin-1,CYGB1_ORYLA,Cytoglobin-1,GO:0005737^cellular_component^cytoplasm,GO:0020037^molecular_function^heme binding,GO:0005506^molecular_function^iron ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,GO:0005737^cellular_component^cytoplasm,GO:0020037^molecular_function^heme binding,GO:0005506^molecular_function^iron ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,KEGG:ola:100049376`KO:K21894,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",PF00042.22^Globin^Globin^12-115^E:5.1e-31,NA,NA,NA,NA,,
no,AD,SAT,DN64066_c0_g2_i3,DN64066_c0_g2,CYGB1_ORYLA,Cytoglobin-1,CYGB1_ORYLA,Cytoglobin-1,GO:0005737^cellular_component^cytoplasm,GO:0020037^molecular_function^heme binding,GO:0005506^molecular_function^iron ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,GO:0005737^cellular_component^cytoplasm,GO:0020037^molecular_function^heme binding,GO:0005506^molecular_function^iron ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,KEGG:ola:100049376`KO:K21894,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",PF00042.22^Globin^Globin^1-83^E:9.8e-25,NA,NA,NA,NA,,
no,AD,SAT,DN30756_c0_g1_i1,DN30756_c0_g1,SMC3_BOVIN,Structural maintenance of chromosomes protein 3,.,NA,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0016363^cellular_component^nuclear matrix,.,NA,NA,NA,NA,KEGG:bta:281729`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN30756_c0_g1_i2,DN30756_c0_g1,SMC3_BOVIN,Structural maintenance of chromosomes protein 3,.,NA,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0016363^cellular_component^nuclear matrix,.,NA,NA,NA,NA,KEGG:bta:281729`KO:K06669,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i19,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^119-252^E:7.2e-28,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i18,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^79-212^E:4.5e-28,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i2,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^2-49^E:1.3e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^36-65^E:2.7e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^52-99^E:7.3e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-115^E:1.4e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^102-152^E:8.4e-15,,
no,AD,SAT,DN647_c0_g1_i7,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,KEGG:mmu:67345`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-117^E:7.7e-39,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i12,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^2-49^E:1.3e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^36-65^E:2.7e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^52-99^E:7.3e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-115^E:1.4e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^102-152^E:8.4e-15,,
no,AD,SAT,DN647_c0_g1_i16,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,KEGG:mmu:67345`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-117^E:7.7e-39,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i11,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^110-338^E:2.2e-60,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i6,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^110-305^E:1.9e-48,NA,NA,NA,NA,,
no,AD,SAT,DN647_c0_g1_i5,DN647_c0_g1,HERC4_HUMAN,Probable E3 ubiquitin-protein ligase HERC4,HERC4_HUMAN,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:hsa:26091`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^2-49^E:5.2e-09,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^36-65^E:1.7e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^52-81^E:1.3e-06,NA,NA,,
no,AD,SAT,DN647_c0_g1_i8,DN647_c0_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,KEGG:mmu:67345`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-117^E:7.7e-39,NA,NA,NA,NA,,
no,AD,SAT,DN3127_c1_g1_i6,DN3127_c1_g1,SATB1_HUMAN,DNA-binding protein SATB1,SATB1_MOUSE,DNA-binding protein SATB1,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0000785^cellular_component^chromatin,GO:0016604^cellular_component^nuclear body,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:20230`KO:K23225,ENOG410YYG8^SATB homeobox,PF16534.5^ULD^Ubiquitin-like oligomerisation domain of SATB^73-170^E:1.4e-36,PF16557.5^CUTL^CUT1-like DNA-binding domain of SATB^177-247^E:2.1e-42,PF02376.15^CUT^CUT domain^368-445^E:1.4e-23,PF02376.15^CUT^CUT domain^493-567^E:5.2e-20,PF00046.29^Homeodomain^Homeodomain^670-722^E:7.3e-07,,
no,AD,SAT,DN3127_c1_g1_i1,DN3127_c1_g1,SATB1_HUMAN,DNA-binding protein SATB1,SATB1_HUMAN,DNA-binding protein SATB1,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:6304`KO:K23225,.,PF16534.5^ULD^Ubiquitin-like oligomerisation domain of SATB^73-170^E:1.3e-36,PF16557.5^CUTL^CUT1-like DNA-binding domain of SATB^177-247^E:2e-42,PF02376.15^CUT^CUT domain^368-445^E:1.3e-23,PF02376.15^CUT^CUT domain^493-567^E:4.9e-20,PF00046.29^Homeodomain^Homeodomain^638-690^E:6.9e-07,,
no,AD,SAT,DN3127_c1_g1_i5,DN3127_c1_g1,SATB1_HUMAN,DNA-binding protein SATB1,SATB1_MOUSE,DNA-binding protein SATB1,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0000785^cellular_component^chromatin,GO:0016604^cellular_component^nuclear body,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:20230`KO:K23225,ENOG410YYG8^SATB homeobox,PF00046.29^Homeodomain^Homeodomain^57-109^E:7.2e-08,NA,NA,NA,NA,,
no,AD,SAT,DN3127_c1_g1_i4,DN3127_c1_g1,SATB1_HUMAN,DNA-binding protein SATB1,SATB1_MOUSE,DNA-binding protein SATB1,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0000785^cellular_component^chromatin,GO:0016604^cellular_component^nuclear body,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:20230`KO:K23225,ENOG410YYG8^SATB homeobox,PF00046.29^Homeodomain^Homeodomain^88-140^E:9.8e-08,NA,NA,NA,NA,,
no,AD,SAT,DN3127_c1_g1_i2,DN3127_c1_g1,SATB1_HUMAN,DNA-binding protein SATB1,SATB1_HUMAN,DNA-binding protein SATB1,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,GO:0005720^cellular_component^nuclear heterochromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:6304`KO:K23225,.,PF16534.5^ULD^Ubiquitin-like oligomerisation domain of SATB^73-170^E:1.3e-36,PF16557.5^CUTL^CUT1-like DNA-binding domain of SATB^177-247^E:2e-42,PF02376.15^CUT^CUT domain^368-445^E:1.3e-23,PF02376.15^CUT^CUT domain^493-567^E:4.9e-20,PF00046.29^Homeodomain^Homeodomain^638-690^E:6.9e-07,,
no,AD,SAT,DN87937_c0_g1_i1,DN87937_c0_g1,FADS1_PAPAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0062076^molecular_function^acyl-CoA delta5-desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,SAT,DN8055_c0_g3_i1,DN8055_c0_g3,SMC1B_MOUSE,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:mmu:140557`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN17392_c0_g1_i4,DN17392_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN17392_c0_g1_i5,DN17392_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN76203_c0_g1_i1,DN76203_c0_g1,KCTD3_MOUSE,BTB/POZ domain-containing protein KCTD3,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:226823`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN2596_c0_g1_i1,DN2596_c0_g1,UN45A_RAT,Protein unc-45 homolog A,RCCD1_HUMAN,RCC1 domain-containing protein 1,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016607^cellular_component^nuclear speck,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0051879^molecular_function^Hsp90 protein binding,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0006325^biological_process^chromatin organization,NA,KEGG:hsa:91433,COG5184^regulator of chromosome condensation,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^3-30^E:2.6e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^18-97^E:4.7e-08,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-113^E:8.2e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^100-149^E:7.1e-14,NA,,
no,AD,SAT,DN2596_c0_g1_i9,DN2596_c0_g1,RCCD1_HUMAN,RCC1 domain-containing protein 1,RCCD1_MACFA,RCC1 domain-containing protein 1,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0006325^biological_process^chromatin organization,NA,GO:0005694^cellular_component^chromosome,GO:0006325^biological_process^chromatin organization,NA,NA,NA,KEGG:mcf:101864818,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^112-160^E:3.4e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^150-177^E:5e-08,NA,NA,NA,,
no,AD,SAT,DN13168_c0_g1_i4,DN13168_c0_g1,RCC2_HUMAN,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,.,NA,NA,NA,NA,KEGG:hsa:55920,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13168_c0_g1_i6,DN13168_c0_g1,RCC2_HUMAN,Protein RCC2,RCC2_HUMAN,Protein RCC2,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,KEGG:hsa:55920,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13168_c0_g1_i7,DN13168_c0_g1,RCC2_HUMAN,Protein RCC2,RCC2_HUMAN,Protein RCC2,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,KEGG:hsa:55920,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13168_c0_g1_i3,DN13168_c0_g1,RCC2_DANRE,Protein RCC2 homolog,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005737^cellular_component^cytoplasm,GO:0030496^cellular_component^midbody,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:dre:406455,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13168_c0_g1_i2,DN13168_c0_g1,RCC2_DANRE,Protein RCC2 homolog,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005737^cellular_component^cytoplasm,GO:0030496^cellular_component^midbody,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:dre:406455,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13108_c0_g1_i1,DN13108_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN13108_c0_g1_i3,DN13108_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^51-123^E:3.1e-16,NA,NA,NA,NA,,
no,AD,SAT,DN97390_c0_g1_i2,DN97390_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN97390_c0_g1_i1,DN97390_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30390_c0_g2_i1,DN30390_c0_g2,KCTD5_BOVIN,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:bta:100125308`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN30390_c0_g2_i9,DN30390_c0_g2,KCTD5_BOVIN,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:bta:100125308`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN30390_c0_g2_i6,DN30390_c0_g2,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN96516_c1_g1_i1,DN96516_c1_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN96516_c1_g1_i3,DN96516_c1_g1,NPL_CHICK,N-acetylneuraminate lyase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008747^molecular_function^N-acetylneuraminate lyase activity,GO:0005975^biological_process^carbohydrate metabolic process,GO:0019262^biological_process^N-acetylneuraminate catabolic process,NA,.,NA,NA,NA,NA,KEGG:gga:429074`KO:K01639,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g1_i6,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^1-238^E:6.6e-57,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g1_i10,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^373-418^E:0.00025,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^476-526^E:3.7e-12,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^513-541^E:1.1e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^529-576^E:3.3e-13,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^583-629^E:9.1e-08,,
no,AD,SAT,DN3739_c0_g1_i11,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,"PF00400.32^WD40^WD domain, G-beta repeat^349-382^E:0.00036","PF00400.32^WD40^WD domain, G-beta repeat^546-576^E:0.14","PF00400.32^WD40^WD domain, G-beta repeat^664-700^E:0.0017",PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^924-968^E:5e-05,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^1013-1038^E:5.3e-07,,
no,AD,SAT,DN3739_c0_g1_i7,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^1-238^E:6.6e-57,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g1_i5,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^1-238^E:6.6e-57,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g1_i2,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,"PF00400.32^WD40^WD domain, G-beta repeat^349-382^E:0.00044","PF00400.32^WD40^WD domain, G-beta repeat^546-576^E:0.17","PF00400.32^WD40^WD domain, G-beta repeat^664-700^E:0.002",PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^924-968^E:6.1e-05,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^1013-1038^E:6.5e-07,,
no,AD,SAT,DN3739_c0_g1_i3,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g1_i1,DN3739_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^1-238^E:6.6e-57,NA,NA,NA,NA,,
no,AD,SAT,DN3739_c0_g3_i1,DN3739_c0_g3,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN70395_c0_g1_i1,DN70395_c0_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN70395_c0_g1_i3,DN70395_c0_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN18868_c0_g1_i3,DN18868_c0_g1,BACD2_CHICK,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,BACD2_CHICK,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,KEGG:gga:417672`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN18868_c0_g1_i1,DN18868_c0_g1,BACD2_CHICK,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,BACD2_CHICK,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,KEGG:gga:417672`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^34-124^E:1.3e-20,PF00651.31^BTB^BTB/POZ domain^34-131^E:2.7e-06,NA,NA,NA,,
no,AD,SAT,DN18868_c0_g1_i5,DN18868_c0_g1,BACD2_CHICK,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,.,NA,NA,NA,NA,KEGG:gga:417672`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN10798_c0_g1_i1,DN10798_c0_g1,HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,.,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^52-326^E:1.1e-69,NA,NA,NA,NA,,
no,AD,SAT,DN10798_c0_g1_i6,DN10798_c0_g1,HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,.,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^64-338^E:1.2e-69,NA,NA,NA,NA,,
no,AD,SAT,DN10798_c0_g1_i5,DN10798_c0_g1,HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,.,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^52-326^E:1.1e-69,NA,NA,NA,NA,,
no,AD,SAT,DN10798_c0_g1_i2,DN10798_c0_g1,HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,.,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^64-338^E:1.2e-69,NA,NA,NA,NA,,
no,AD,SAT,DN10798_c0_g2_i1,DN10798_c0_g2,HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",HMGCL_CHICK,"Hydroxymethylglutaryl-CoA lyase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0005777^cellular_component^peroxisome,GO:0004419^molecular_function^hydroxymethylglutaryl-CoA lyase activity,GO:0046872^molecular_function^metal ion binding,.,COG0119^Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity),PF00682.19^HMGL-like^HMGL-like^52-117^E:2.6e-17,NA,NA,NA,NA,,
no,AD,SAT,DN1954_c0_g1_i2,DN1954_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,PF00173.28^Cyt-b5^Cytochrome b5-like Heme/Steroid binding domain^14-91^E:6.4e-19,PF00487.24^FA_desaturase^Fatty acid desaturase^156-414^E:3.8e-31,NA,NA,NA,,
no,AD,SAT,DN1954_c0_g1_i5,DN1954_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,PF00173.28^Cyt-b5^Cytochrome b5-like Heme/Steroid binding domain^14-91^E:6.6e-19,PF00487.24^FA_desaturase^Fatty acid desaturase^156-414^E:4e-31,NA,NA,NA,,
no,AD,SAT,DN1954_c0_g1_i6,DN1954_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN42442_c0_g1_i1,DN42442_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN7703_c0_g1_i3,DN7703_c0_g1,SMC1A_HUMAN,Structural maintenance of chromosomes protein 1A,.,NA,GO:0005694^cellular_component^chromosome,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0008278^cellular_component^cohesin complex,GO:0000777^cellular_component^condensed chromosome kinetochore,GO:0000794^cellular_component^condensed nuclear chromosome,.,NA,NA,NA,NA,KEGG:hsa:8243`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN7789_c0_g1_i1,DN7789_c0_g1,CYGB_RAT,Cytoglobin,CYGB_RAT,Cytoglobin,GO:0005737^cellular_component^cytoplasm,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,GO:0016607^cellular_component^nuclear speck,GO:0004096^molecular_function^catalase activity,GO:0005737^cellular_component^cytoplasm,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,GO:0016607^cellular_component^nuclear speck,GO:0004096^molecular_function^catalase activity,KEGG:rno:170520`KO:K21894,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",PF00042.22^Globin^Globin^160-268^E:4.2e-24,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i13,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_MOUSE,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:mmu:108837,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i3,DN7783_c0_g1,IBTK_MOUSE,Inhibitor of Bruton tyrosine kinase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,.,NA,NA,NA,NA,KEGG:mmu:108837,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i5,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i8,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i2,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i7,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,PF12796.7^Ank_2^Ankyrin repeats (3 copies)^34-117^E:1.7e-08,PF13637.6^Ank_4^Ankyrin repeats (many copies)^53-103^E:7.9e-06,PF13857.6^Ank_5^Ankyrin repeats (many copies)^87-126^E:4.2e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^144-193^E:2.4e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^196-245^E:5.2e-11,,
no,AD,SAT,DN7783_c0_g1_i11,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i6,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_MOUSE,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:mmu:108837,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7783_c0_g1_i14,DN7783_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,PF00651.31^BTB^BTB/POZ domain^80-170^E:3e-14,PF00651.31^BTB^BTB/POZ domain^284-393^E:2.3e-16,NA,NA,NA,,
no,AD,SAT,DN49719_c0_g1_i1,DN49719_c0_g1,SATB2_HUMAN,DNA-binding protein SATB2,SATB2_HUMAN,DNA-binding protein SATB2,GO:0000118^cellular_component^histone deacetylase complex,GO:0000790^cellular_component^nuclear chromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0000118^cellular_component^histone deacetylase complex,GO:0000790^cellular_component^nuclear chromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:23314`KO:K23226,ENOG41113K2^SATB homeobox 2,PF16534.5^ULD^Ubiquitin-like oligomerisation domain of SATB^59-156^E:3.6e-36,PF16557.5^CUTL^CUT1-like DNA-binding domain of SATB^163-233^E:1.8e-42,PF02376.15^CUT^CUT domain^356-434^E:1.9e-24,PF02376.15^CUT^CUT domain^481-556^E:1.8e-21,PF00046.29^Homeodomain^Homeodomain^614-669^E:6e-06,,
no,AD,SAT,DN49719_c0_g1_i3,DN49719_c0_g1,SATB2_HUMAN,DNA-binding protein SATB2,.,NA,GO:0000118^cellular_component^histone deacetylase complex,GO:0000790^cellular_component^nuclear chromatin,GO:0016363^cellular_component^nuclear matrix,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:23314`KO:K23226,ENOG41113K2^SATB homeobox 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i6,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i3,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,PF02214.22^BTB_2^BTB/POZ domain^14-99^E:4.7e-23,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i4,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,PF02214.22^BTB_2^BTB/POZ domain^14-99^E:7.8e-23,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i1,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i2,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,PF02214.22^BTB_2^BTB/POZ domain^14-99^E:1.3e-22,NA,NA,NA,NA,,
no,AD,SAT,DN6897_c0_g1_i5,DN6897_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN24343_c1_g1_i1,DN24343_c1_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN23507_c0_g1_i2,DN23507_c0_g1,SAT2_HUMAN,Diamine acetyltransferase 2,SAT2_HUMAN,Diamine acetyltransferase 2,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,KEGG:hsa:112483`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,PF00583.25^Acetyltransf_1^Acetyltransferase (GNAT) family^36-142^E:2.8e-18,PF13508.7^Acetyltransf_7^Acetyltransferase (GNAT) domain^58-142^E:3.2e-09,NA,NA,NA,,
no,AD,SAT,DN23507_c0_g1_i1,DN23507_c0_g1,SAT2_HUMAN,Diamine acetyltransferase 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0070062^cellular_component^extracellular exosome,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:112483`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g2_i4,DN23677_c0_g2,FADS2_BOVIN,Acyl-CoA 6-desaturase,FADS2_BOVIN,Acyl-CoA 6-desaturase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,PF00487.24^FA_desaturase^Fatty acid desaturase^36-294^E:1.5e-33,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g2_i1,DN23677_c0_g2,FADS2_BOVIN,Acyl-CoA 6-desaturase,FADS2_BOVIN,Acyl-CoA 6-desaturase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,PF00487.24^FA_desaturase^Fatty acid desaturase^150-408^E:4.1e-33,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g2_i3,DN23677_c0_g2,FADS2_BOVIN,Acyl-CoA 6-desaturase,FADS2_BOVIN,Acyl-CoA 6-desaturase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,PF00173.28^Cyt-b5^Cytochrome b5-like Heme/Steroid binding domain^22-95^E:3.1e-21,PF00487.24^FA_desaturase^Fatty acid desaturase^158-416^E:3.7e-33,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g3_i3,DN23677_c0_g3,FADS2_RAT,Acyl-CoA 6-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0045485^molecular_function^omega-6 fatty acid desaturase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,.,NA,NA,NA,NA,KEGG:rno:83512`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g3_i1,DN23677_c0_g3,FADS2_MOUSE,Acyl-CoA 6-desaturase {ECO:0000305|PubMed:9867867},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,.,NA,NA,NA,NA,KEGG:mmu:56473`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g3_i4,DN23677_c0_g3,FADS2_BOVIN,Acyl-CoA 6-desaturase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN23677_c0_g4_i1,DN23677_c0_g4,FADS2_BOVIN,Acyl-CoA 6-desaturase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN40901_c0_g1_i1,DN40901_c0_g1,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,.,NA,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:8924`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN22855_c0_g1_i1,DN22855_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN64358_c0_g1_i1,DN64358_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN64375_c0_g1_i3,DN64375_c0_g1,RCBT2_RAT,RCC1 and BTB domain-containing protein 2,.,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:rno:290363`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN3268_c0_g1_i3,DN3268_c0_g1,HBE_CHICK,Hemoglobin subunit epsilon,HBE_CHICK,Hemoglobin subunit epsilon,GO:0031838^cellular_component^haptoglobin-hemoglobin complex,GO:0005833^cellular_component^hemoglobin complex,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0043177^molecular_function^organic acid binding,GO:0031838^cellular_component^haptoglobin-hemoglobin complex,GO:0005833^cellular_component^hemoglobin complex,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0043177^molecular_function^organic acid binding,KEGG:gga:107049060,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",PF00042.22^Globin^Globin^99-202^E:4.1e-29,NA,NA,NA,NA,,
no,AD,SAT,DN3268_c0_g3_i1,DN3268_c0_g3,HBE_CHICK,Hemoglobin subunit epsilon,.,NA,GO:0031838^cellular_component^haptoglobin-hemoglobin complex,GO:0005833^cellular_component^hemoglobin complex,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0043177^molecular_function^organic acid binding,.,NA,NA,NA,NA,KEGG:gga:107049060,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",.,NA,NA,NA,NA,,
no,AD,SAT,DN63610_c0_g1_i4,DN63610_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN63610_c0_g1_i2,DN63610_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN63610_c0_g1_i3,DN63610_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN1481_c0_g1_i6,DN1481_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^70-125^E:4.5e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^136-194^E:6.9e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^181-210^E:1.1e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^199-249^E:2.7e-08,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^237-266^E:6.5e-07,,
no,AD,SAT,DN1481_c0_g1_i1,DN1481_c0_g1,RCC1L_HUMAN,RCC1-like G exchanging factor-like protein,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005525^molecular_function^GTP binding,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0003723^molecular_function^RNA binding,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^70-125^E:1.8e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^136-194^E:2.6e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^181-210^E:5.2e-08,NA,NA,,
no,AD,SAT,DN1481_c0_g1_i2,DN1481_c0_g1,RCC1L_HUMAN,RCC1-like G exchanging factor-like protein,RCC1L_HUMAN,RCC1-like G exchanging factor-like protein,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005525^molecular_function^GTP binding,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0003723^molecular_function^RNA binding,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005525^molecular_function^GTP binding,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0003723^molecular_function^RNA binding,KEGG:hsa:81554`KO:K23495,COG5184^regulator of chromosome condensation,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^1-28^E:3.7e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^15-63^E:0.00011,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^68-116^E:4.5e-06,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^179-223^E:5.6e-10,NA,,
no,AD,SAT,DN8127_c0_g1_i4,DN8127_c0_g1,NGB_MACMU,Neuroglobin,.,NA,GO:0043204^cellular_component^perikaryon,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,.,NA,NA,NA,NA,KEGG:mcc:641331`KO:K21893,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",.,NA,NA,NA,NA,,
no,AD,SAT,DN8127_c0_g1_i7,DN8127_c0_g1,NGB_MACMU,Neuroglobin,NGB_BOVIN,Neuroglobin,GO:0043204^cellular_component^perikaryon,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,GO:0043204^cellular_component^perikaryon,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,KEGG:bta:414920`KO:K21893,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",PF00042.22^Globin^Globin^15-123^E:6.2e-16,NA,NA,NA,NA,,
no,AD,SAT,DN53725_c0_g1_i1,DN53725_c0_g1,BACD3_HUMAN,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033},.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017049^molecular_function^GTP-Rho binding,GO:0005112^molecular_function^Notch binding,.,NA,NA,NA,NA,KEGG:hsa:83892`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN11075_c0_g1_i3,DN11075_c0_g1,KCD21_HUMAN,BTB/POZ domain-containing protein KCTD21,KCD21_HUMAN,BTB/POZ domain-containing protein KCTD21,GO:0097602^molecular_function^cullin family protein binding,GO:0042826^molecular_function^histone deacetylase binding,GO:0042802^molecular_function^identical protein binding,GO:0045879^biological_process^negative regulation of smoothened signaling pathway,GO:0051260^biological_process^protein homooligomerization,GO:0097602^molecular_function^cullin family protein binding,GO:0042826^molecular_function^histone deacetylase binding,GO:0042802^molecular_function^identical protein binding,GO:0045879^biological_process^negative regulation of smoothened signaling pathway,GO:0051260^biological_process^protein homooligomerization,KEGG:hsa:283219`KO:K21922,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^5-93^E:2.8e-21,PF16017.5^BTB_3^BTB/POZ domain^5-90^E:7.3e-05,NA,NA,NA,,
no,AD,SAT,DN11075_c0_g1_i7,DN11075_c0_g1,KCD21_HUMAN,BTB/POZ domain-containing protein KCTD21,KCD21_HUMAN,BTB/POZ domain-containing protein KCTD21,GO:0097602^molecular_function^cullin family protein binding,GO:0042826^molecular_function^histone deacetylase binding,GO:0042802^molecular_function^identical protein binding,GO:0045879^biological_process^negative regulation of smoothened signaling pathway,GO:0051260^biological_process^protein homooligomerization,GO:0097602^molecular_function^cullin family protein binding,GO:0042826^molecular_function^histone deacetylase binding,GO:0042802^molecular_function^identical protein binding,GO:0045879^biological_process^negative regulation of smoothened signaling pathway,GO:0051260^biological_process^protein homooligomerization,KEGG:hsa:283219`KO:K21922,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^5-93^E:2.8e-21,PF16017.5^BTB_3^BTB/POZ domain^5-90^E:7.3e-05,NA,NA,NA,,
no,AD,SAT,DN11117_c1_g1_i6,DN11117_c1_g1,DHDDS_MOUSE,Dehydrodolichyl diphosphate synthase complex subunit Dhdds {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:67422`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN11117_c1_g1_i5,DN11117_c1_g1,DHDDS_MOUSE,Dehydrodolichyl diphosphate synthase complex subunit Dhdds {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:67422`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN43926_c0_g1_i1,DN43926_c0_g1,RCC2_HUMAN,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0005829^cellular_component^cytosol,GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,.,NA,NA,NA,NA,KEGG:hsa:55920,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN34894_c0_g1_i1,DN34894_c0_g1,FADS2_BOVIN,Acyl-CoA 6-desaturase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,.,NA,NA,NA,NA,KEGG:bta:521822`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN51030_c0_g1_i12,DN51030_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^103-237^E:1.2e-19,NA,NA,NA,NA,,
no,AD,SAT,DN51030_c0_g1_i14,DN51030_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN58382_c0_g1_i2,DN58382_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN2638_c0_g1_i1,DN2638_c0_g1,SCD5_BOVIN,Stearoyl-CoA desaturase 5,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005506^molecular_function^iron ion binding,GO:0016491^molecular_function^oxidoreductase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,.,NA,NA,NA,NA,KEGG:bta:617419`KO:K00507,COG1398^desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN2638_c0_g2_i1,DN2638_c0_g2,SCD5_BOVIN,Stearoyl-CoA desaturase 5,SCD5_BOVIN,Stearoyl-CoA desaturase 5,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005506^molecular_function^iron ion binding,GO:0016491^molecular_function^oxidoreductase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005506^molecular_function^iron ion binding,GO:0016491^molecular_function^oxidoreductase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,KEGG:bta:617419`KO:K00507,COG1398^desaturase,PF00487.24^FA_desaturase^Fatty acid desaturase^60-263^E:8.3e-17,NA,NA,NA,NA,,
no,AD,SAT,DN2638_c0_g3_i1,DN2638_c0_g3,ACOD_CYPCA,Acyl-CoA desaturase,ACOD_BOVIN,Acyl-CoA desaturase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005506^molecular_function^iron ion binding,GO:0016491^molecular_function^oxidoreductase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,GO:0005623^cellular_component^cell,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005730^cellular_component^nucleolus,KEGG:bta:280924`KO:K00507,COG1398^desaturase,PF00487.24^FA_desaturase^Fatty acid desaturase^103-306^E:4.5e-15,NA,NA,NA,NA,,
no,AD,SAT,DN57558_c0_g1_i1,DN57558_c0_g1,RCC2_MOUSE,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,.,NA,NA,NA,NA,KEGG:mmu:108911,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN48590_c0_g1_i2,DN48590_c0_g1,RCBT2_PONAB,RCC1 and BTB domain-containing protein 2,.,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:pon:100172062`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN23292_c0_g1_i1,DN23292_c0_g1,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN40425_c0_g3_i1,DN40425_c0_g3,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN40425_c1_g1_i1,DN40425_c1_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN7548_c1_g1_i1,DN7548_c1_g1,DEGS1_CHICK,Sphingolipid delta(4)-desaturase DES1,DEGS1_CHICK,Sphingolipid delta(4)-desaturase DES1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0046513^biological_process^ceramide biosynthetic process,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0046513^biological_process^ceramide biosynthetic process,KEGG:gga:421327`KO:K04712,ENOG410XQVT^sphingolipid delta-4 desaturase activity,PF08557.10^Lipid_DES^Sphingolipid Delta4-desaturase (DES)^7-41^E:1.2e-19,PF00487.24^FA_desaturase^Fatty acid desaturase^67-285^E:4.7e-25,NA,NA,NA,,
no,AD,SAT,DN7548_c1_g1_i8,DN7548_c1_g1,DEGS1_CHICK,Sphingolipid delta(4)-desaturase DES1,DEGS1_CHICK,Sphingolipid delta(4)-desaturase DES1,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0046513^biological_process^ceramide biosynthetic process,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0046513^biological_process^ceramide biosynthetic process,KEGG:gga:421327`KO:K04712,ENOG410XQVT^sphingolipid delta-4 desaturase activity,PF08557.10^Lipid_DES^Sphingolipid Delta4-desaturase (DES)^7-41^E:1.2e-19,PF00487.24^FA_desaturase^Fatty acid desaturase^67-285^E:4.7e-25,NA,NA,NA,,
no,AD,SAT,DN31408_c2_g1_i1,DN31408_c2_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN13365_c0_g1_i3,DN13365_c0_g1,FADS6_BOVIN,Fatty acid desaturase 6,FADS6_HUMAN,Fatty acid desaturase 6,GO:0016021^cellular_component^integral component of membrane,GO:0016491^molecular_function^oxidoreductase activity,GO:0006633^biological_process^fatty acid biosynthetic process,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0016491^molecular_function^oxidoreductase activity,GO:0006633^biological_process^fatty acid biosynthetic process,NA,NA,KEGG:hsa:283985`KO:K12419,"ENOG4110K0A^Fatty acid desaturase domain family, member 6",PF00487.24^FA_desaturase^Fatty acid desaturase^141-384^E:5.2e-12,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i8,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i3,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i7,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i5,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i4,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g2_i2,DN30667_c0_g2,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN30667_c0_g3_i1,DN30667_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN37924_c1_g1_i1,DN37924_c1_g1,HERC4_RAT,Probable E3 ubiquitin-protein ligase HERC4,.,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,.,NA,NA,NA,NA,KEGG:rno:309758`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN96793_c0_g1_i1,DN96793_c0_g1,RCC2_DANRE,Protein RCC2 homolog,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005737^cellular_component^cytoplasm,GO:0030496^cellular_component^midbody,GO:0005730^cellular_component^nucleolus,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:dre:406455,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN80447_c0_g1_i1,DN80447_c0_g1,DEGS2_MOUSE,Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0000170^molecular_function^sphingosine hydroxylase activity,GO:0046513^biological_process^ceramide biosynthetic process,.,NA,NA,NA,NA,KEGG:mmu:70059`KO:K04712,ENOG410XQVT^sphingolipid delta-4 desaturase activity,.,NA,NA,NA,NA,,
no,AD,SAT,DN8872_c1_g1_i6,DN8872_c1_g1,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,.,NA,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN8872_c1_g1_i5,DN8872_c1_g1,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:22985`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN8872_c1_g1_i7,DN8872_c1_g1,ACINU_HUMAN,Apoptotic chromatin condensation inducer in the nucleus,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN8872_c1_g1_i9,DN8872_c1_g1,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,.,NA,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN18059_c0_g2_i2,DN18059_c0_g2,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN18059_c0_g2_i6,DN18059_c0_g2,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN18059_c0_g2_i1,DN18059_c0_g2,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN1277_c0_g1_i9,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^118-168^E:1e-14,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^155-184^E:2.1e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^171-221^E:1.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^211-237^E:8.9e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^224-273^E:1.7e-15,,
no,AD,SAT,DN1277_c0_g1_i8,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^32-82^E:8.9e-15,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^69-98^E:1.8e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^85-135^E:1.6e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^125-151^E:7.9e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^138-187^E:1.5e-15,,
no,AD,SAT,DN1277_c0_g1_i4,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^118-168^E:8e-15,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^155-184^E:1.7e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^171-221^E:1.4e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^211-237^E:7.3e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^224-263^E:2.4e-09,,
no,AD,SAT,DN1277_c0_g1_i5,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^118-168^E:1.2e-14,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^155-184^E:2.4e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^171-221^E:2.1e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^211-237^E:0.0001,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^224-273^E:2e-15,,
no,AD,SAT,DN1277_c0_g1_i3,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^118-168^E:1e-14,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^155-184^E:2.1e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^171-221^E:1.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^211-237^E:8.9e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^224-273^E:1.7e-15,,
no,AD,SAT,DN1277_c0_g1_i1,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^32-82^E:6.1e-15,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^69-98^E:1.3e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^85-135^E:1.1e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^125-151^E:5.8e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^138-187^E:1e-15,,
no,AD,SAT,DN1277_c0_g1_i10,DN1277_c0_g1,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^118-168^E:1.2e-14,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^155-184^E:2.4e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^171-221^E:2.1e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^211-237^E:0.0001,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^224-273^E:2e-15,,
no,AD,SAT,DN1277_c0_g3_i1,DN1277_c0_g3,RCBT2_MOUSE,RCC1 and BTB domain-containing protein 2,.,NA,GO:0001669^cellular_component^acrosomal vesicle,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:105670`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i15,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^283-579^E:2.1e-82,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i12,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^30-77^E:3.2e-05,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^64-93^E:5.8e-10,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^80-127^E:2.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^114-143^E:2.5e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^131-180^E:1.6e-12,,
no,AD,SAT,DN1211_c0_g1_i8,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^283-579^E:2.1e-82,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i13,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^35-99^E:9.6e-08,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^475-771^E:4e-82,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i5,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^110-217^E:1.8e-17,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i17,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^110-406^E:7.5e-83,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i11,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^1-117^E:3.6e-38,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i7,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^4-40^E:6.2e-07,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^28-58^E:2.5e-05,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^45-109^E:4.7e-09,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i9,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i2,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i14,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^309-416^E:7e-17,NA,NA,NA,NA,,
no,AD,SAT,DN1211_c0_g1_i16,DN1211_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^110-406^E:7.5e-83,NA,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i2,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^133-160^E:1.1e-07,NA,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i10,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^1-78^E:6.2e-33,NA,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i12,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^117-222^E:7.2e-49,PF02214.22^BTB_2^BTB/POZ domain^118-206^E:3.5e-05,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i3,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^117-222^E:7.2e-49,PF02214.22^BTB_2^BTB/POZ domain^118-206^E:3.5e-05,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i8,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^1-78^E:2.8e-33,NA,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i11,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^258-363^E:1.4e-48,PF02214.22^BTB_2^BTB/POZ domain^259-347^E:6.8e-05,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i9,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,PF16017.5^BTB_3^BTB/POZ domain^117-222^E:7.2e-49,PF02214.22^BTB_2^BTB/POZ domain^118-206^E:3.5e-05,NA,NA,NA,,
no,AD,SAT,DN1271_c0_g2_i5,DN1271_c0_g2,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,.,NA,NA,NA,NA,,
no,AD,SAT,DN68851_c0_g1_i1,DN68851_c0_g1,RCC2_MOUSE,Protein RCC2,.,NA,"GO:0034506^cellular_component^chromosome, centromeric core domain",GO:0031901^cellular_component^early endosome membrane,GO:0005874^cellular_component^microtubule,GO:0030496^cellular_component^midbody,GO:1990023^cellular_component^mitotic spindle midzone,.,NA,NA,NA,NA,KEGG:mmu:108911,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN42728_c0_g1_i1,DN42728_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN74481_c0_g1_i1,DN74481_c0_g1,KCTD8_MOUSE,BTB/POZ domain-containing protein KCTD8,KCTD8_MOUSE,BTB/POZ domain-containing protein KCTD8,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0043235^cellular_component^receptor complex,GO:0051260^biological_process^protein homooligomerization,KEGG:mmu:243043`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^29-123^E:7.1e-16,NA,NA,NA,NA,,
no,AD,SAT,DN31039_c0_g1_i2,DN31039_c0_g1,KCD20_HUMAN,BTB/POZ domain-containing protein KCTD20,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0042327^biological_process^positive regulation of phosphorylation,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:222658,ENOG410YA9I^Potassium channel tetramerisation domain containing 20,.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i26,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,RT29_BOVIN,"28S ribosomal protein S29, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0006915^biological_process^apoptotic process,KEGG:bta:535567,ENOG410XSDC^Death associated protein 3,PF10236.9^DAP3^Mitochondrial ribosomal death-associated protein 3^2-73^E:7.7e-15,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i34,DN1517_c0_g1,MSTO1_MOUSE,Protein misato homolog 1,MSTO1_HUMAN,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:hsa:55154,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^2-186^E:6.9e-25,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i31,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,RT29_BOVIN,"28S ribosomal protein S29, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003735^molecular_function^structural constituent of ribosome,GO:0006915^biological_process^apoptotic process,KEGG:bta:535567,ENOG410XSDC^Death associated protein 3,PF10236.9^DAP3^Mitochondrial ribosomal death-associated protein 3^2-73^E:7.7e-15,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i22,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,MSTO1_DANRE,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0000070^biological_process^mitotic sister chromatid segregation,KEGG:dre:334306,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i41,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,MSTO1_DANRE,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0000070^biological_process^mitotic sister chromatid segregation,KEGG:dre:334306,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i30,DN1517_c0_g1,MSTO1_HUMAN,Protein misato homolog 1,MSTO1_HUMAN,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:hsa:55154,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^28-216^E:5.6e-25,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i3,DN1517_c0_g1,MSTO1_HUMAN,Protein misato homolog 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,.,NA,NA,NA,NA,KEGG:hsa:55154,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i19,DN1517_c0_g1,RT29_MOUSE,"28S ribosomal protein S29, mitochondrial",MSTO1_DANRE,Protein misato homolog 1,GO:0005759^cellular_component^mitochondrial matrix,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003735^molecular_function^structural constituent of ribosome,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0000070^biological_process^mitotic sister chromatid segregation,KEGG:dre:334306,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i43,DN1517_c0_g1,MSTO1_MACFA,Protein misato homolog 1,MSTO1_HUMAN,Protein misato homolog 1,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:hsa:55154,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^78-266^E:3.6e-25,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i39,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,MSTO1_BOVIN,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^2-186^E:5.3e-24,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i13,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,RT29_MOUSE,"28S ribosomal protein S29, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005759^cellular_component^mitochondrial matrix,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003735^molecular_function^structural constituent of ribosome,KEGG:mmu:65111`KO:K17408,ENOG410XSDC^Death associated protein 3,PF10236.9^DAP3^Mitochondrial ribosomal death-associated protein 3^3-99^E:9e-20,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i10,DN1517_c0_g1,RT29_MOUSE,"28S ribosomal protein S29, mitochondrial",MSTO1_BOVIN,Protein misato homolog 1,GO:0005759^cellular_component^mitochondrial matrix,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003735^molecular_function^structural constituent of ribosome,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^2-186^E:5.3e-24,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i20,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,MSTO1_DANRE,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0000070^biological_process^mitotic sister chromatid segregation,KEGG:dre:334306,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i4,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,MSTO1_BOVIN,Protein misato homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),PF14881.6^Tubulin_3^Tubulin domain^35-223^E:1.2e-24,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i24,DN1517_c0_g1,RT29_MOUSE,"28S ribosomal protein S29, mitochondrial",MSTO1_DANRE,Protein misato homolog 1,GO:0005759^cellular_component^mitochondrial matrix,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003735^molecular_function^structural constituent of ribosome,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0000070^biological_process^mitotic sister chromatid segregation,KEGG:dre:334306,ENOG410XPM0^Misato homolog 1 (Drosophila),PF10644.9^Misat_Tub_SegII^Misato Segment II tubulin-like domain^5-70^E:3.4e-06,NA,NA,NA,NA,,
no,AD,SAT,DN1517_c0_g1_i5,DN1517_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,RT29_MOUSE,"28S ribosomal protein S29, mitochondrial",GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,GO:0005759^cellular_component^mitochondrial matrix,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0003735^molecular_function^structural constituent of ribosome,KEGG:mmu:65111`KO:K17408,ENOG410XSDC^Death associated protein 3,PF10236.9^DAP3^Mitochondrial ribosomal death-associated protein 3^98-157^E:9.7e-21,NA,NA,NA,NA,,
no,AD,SAT,DN1514_c0_g1_i2,DN1514_c0_g1,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,KEGG:gga:417547`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^119-173^E:3.6e-10,NA,NA,NA,NA,,
no,AD,SAT,DN1514_c0_g1_i4,DN1514_c0_g1,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,KEGG:gga:417547`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i4,DN1584_c0_g1,PP16B_BOVIN,Protein phosphatase 1 regulatory inhibitor subunit 16B,SHKB1_MOUSE,SH3KBP1-binding protein 1,GO:0042995^cellular_component^cell projection,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:mmu:192192`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i5,DN1584_c0_g1,PP16B_BOVIN,Protein phosphatase 1 regulatory inhibitor subunit 16B,SHKB1_HUMAN,SH3KBP1-binding protein 1,GO:0042995^cellular_component^cell projection,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:hsa:92799`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i1,DN1584_c0_g1,SHKB1_RAT,SH3KBP1-binding protein 1,SHKB1_RAT,SH3KBP1-binding protein 1,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:rno:292735`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i11,DN1584_c0_g1,SHKB1_RAT,SH3KBP1-binding protein 1,SHKB1_MOUSE,SH3KBP1-binding protein 1,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:mmu:192192`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i2,DN1584_c0_g1,PP16B_BOVIN,Protein phosphatase 1 regulatory inhibitor subunit 16B,SHKB1_MOUSE,SH3KBP1-binding protein 1,GO:0042995^cellular_component^cell projection,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:mmu:192192`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i13,DN1584_c0_g1,PP16B_BOVIN,Protein phosphatase 1 regulatory inhibitor subunit 16B,SHKB1_HUMAN,SH3KBP1-binding protein 1,GO:0042995^cellular_component^cell projection,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0048471^cellular_component^perinuclear region of cytoplasm,GO:0005886^cellular_component^plasma membrane,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:hsa:92799`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN1584_c0_g1_i14,DN1584_c0_g1,SHKB1_RAT,SH3KBP1-binding protein 1,SHKB1_RAT,SH3KBP1-binding protein 1,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0005764^cellular_component^lysosome,GO:0045742^biological_process^positive regulation of epidermal growth factor receptor signaling pathway,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:rno:292735`KO:K21953,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN30210_c0_g1_i6,DN30210_c0_g1,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN30210_c0_g1_i3,DN30210_c0_g1,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,ACINU_MOUSE,Apoptotic chromatin condensation inducer in the nucleus,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,GO:0061574^cellular_component^ASAP complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005730^cellular_component^nucleolus,GO:0005654^cellular_component^nucleoplasm,KEGG:mmu:56215`KO:K12875,ENOG4111HR1^Apoptotic chromatin condensation inducer 1,.,NA,NA,NA,NA,,
no,AD,SAT,DN21164_c0_g1_i3,DN21164_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN21172_c0_g1_i1,DN21172_c0_g1,OXSM_HUMAN,"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial",OXSM_HUMAN,"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial",GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0004315^molecular_function^3-oxoacyl-[acyl-carrier-protein] synthase activity,GO:0006637^biological_process^acyl-CoA metabolic process,GO:0006633^biological_process^fatty acid biosynthetic process,GO:0005829^cellular_component^cytosol,GO:0005739^cellular_component^mitochondrion,GO:0004315^molecular_function^3-oxoacyl-[acyl-carrier-protein] synthase activity,GO:0006637^biological_process^acyl-CoA metabolic process,GO:0006633^biological_process^fatty acid biosynthetic process,KEGG:hsa:54995`KO:K09458,COG0304^Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity),"PF00109.26^ketoacyl-synt^Beta-ketoacyl synthase, N-terminal domain^42-293^E:4.6e-56","PF02801.22^Ketoacyl-synt_C^Beta-ketoacyl synthase, C-terminal domain^301-415^E:5e-38",NA,NA,NA,,
no,AD,SAT,DN19543_c0_g1_i1,DN19543_c0_g1,RCC1L_MOUSE,RCC1-like G exchanging factor-like protein,.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0005739^cellular_component^mitochondrion,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0005087^molecular_function^Ran guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:mmu:94254`KO:K23495,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN20452_c0_g1_i1,DN20452_c0_g1,KCTD5_MOUSE,BTB/POZ domain-containing protein KCTD5,KCTD5_RAT,BTB/POZ domain-containing protein KCTD5,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,KEGG:rno:287109`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN20452_c0_g1_i3,DN20452_c0_g1,KCTD5_MOUSE,BTB/POZ domain-containing protein KCTD5,KCTD5_HUMAN,BTB/POZ domain-containing protein KCTD5,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,KEGG:hsa:54442`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^52-140^E:2.5e-22,NA,NA,NA,NA,,
no,AD,SAT,DN20452_c0_g1_i5,DN20452_c0_g1,KCTD5_MOUSE,BTB/POZ domain-containing protein KCTD5,KCTD5_HUMAN,BTB/POZ domain-containing protein KCTD5,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,KEGG:hsa:54442`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^52-140^E:1.8e-22,NA,NA,NA,NA,,
no,AD,SAT,DN20452_c0_g1_i2,DN20452_c0_g1,KCTD5_MOUSE,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:mmu:69259`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN20452_c0_g1_i6,DN20452_c0_g1,KCTD5_RAT,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:rno:287109`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i15,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^5-92^E:1.9e-21,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i6,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^5-92^E:1.9e-21,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i8,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^14-101^E:2e-21,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i10,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^14-101^E:2e-21,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i14,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^14-101^E:2e-21,NA,NA,NA,NA,,
no,AD,SAT,DN5560_c0_g1_i3,DN5560_c0_g1,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,KCTD6_HUMAN,BTB/POZ domain-containing protein KCTD6,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,GO:0005829^cellular_component^cytosol,GO:0031430^cellular_component^M band,GO:0030506^molecular_function^ankyrin binding,GO:0097602^molecular_function^cullin family protein binding,GO:0042802^molecular_function^identical protein binding,KEGG:hsa:200845`KO:K21916,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^5-92^E:1.9e-21,NA,NA,NA,NA,,
no,AD,SAT,DN78372_c0_g1_i1,DN78372_c0_g1,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,.,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,.,NA,NA,NA,NA,KEGG:gga:417547`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN69361_c0_g1_i3,DN69361_c0_g1,SRGEF_BOVIN,Secretion-regulating guanine nucleotide exchange factor,.,NA,GO:0016235^cellular_component^aggresome,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0050709^biological_process^negative regulation of protein secretion,.,NA,NA,NA,NA,KEGG:bta:534377`KO:K15421,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN69361_c0_g2_i1,DN69361_c0_g2,SRGEF_HUMAN,Secretion-regulating guanine nucleotide exchange factor,SRGEF_HUMAN,Secretion-regulating guanine nucleotide exchange factor,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:26297`KO:K15421,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^56-102^E:1.7e-10,NA,NA,NA,NA,,
no,AD,SAT,DN10574_c0_g1_i6,DN10574_c0_g1,KCD14_HUMAN,BTB/POZ domain-containing protein KCTD14,KCD14_HUMAN,BTB/POZ domain-containing protein KCTD14,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,KEGG:hsa:65987`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^25-109^E:2.4e-16,NA,NA,NA,NA,,
no,AD,SAT,DN10574_c0_g1_i8,DN10574_c0_g1,KCD14_HUMAN,BTB/POZ domain-containing protein KCTD14,.,NA,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:65987`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN9581_c0_g1_i1,DN9581_c0_g1,SMC1A_MOUSE,Structural maintenance of chromosomes protein 1A,SMC1A_BOVIN,Structural maintenance of chromosomes protein 1A,GO:0008278^cellular_component^cohesin complex,GO:0005829^cellular_component^cytosol,GO:0000776^cellular_component^kinetochore,GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0005829^cellular_component^cytosol,GO:0000776^cellular_component^kinetochore,GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,GO:0016363^cellular_component^nuclear matrix,KEGG:bta:282370`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^10-136^E:4.1e-32,PF13175.6^AAA_15^AAA ATPase domain^11-337^E:2e-12,PF13555.6^AAA_29^P-loop containing region of AAA domain^11-57^E:4e-08,PF13476.6^AAA_23^AAA domain^14-303^E:2.5e-14,"PF13304.6^AAA_21^AAA domain, putative AbiEii toxin, Type IV TA system^34-58^E:1.7e-08",,
no,AD,SAT,DN8614_c0_g3_i1,DN8614_c0_g3,DEGS2_MOUSE,Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042284^molecular_function^sphingolipid delta-4 desaturase activity,GO:0000170^molecular_function^sphingosine hydroxylase activity,GO:0046513^biological_process^ceramide biosynthetic process,.,NA,NA,NA,NA,KEGG:mmu:70059`KO:K04712,ENOG410XQVT^sphingolipid delta-4 desaturase activity,.,NA,NA,NA,NA,,
no,AD,SAT,DN1097_c0_g1_i5,DN1097_c0_g1,NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,.,NA,NA,NA,NA,KEGG:hsa:116150`KO:K19177,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN1097_c0_g1_i8,DN1097_c0_g1,NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,KEGG:hsa:116150`KO:K19177,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),PF01255.19^Prenyltransf^Putative undecaprenyl diphosphate synthase^138-251^E:2.2e-07,NA,NA,NA,NA,,
no,AD,SAT,DN1097_c0_g1_i1,DN1097_c0_g1,NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,KEGG:hsa:116150`KO:K19177,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN1097_c0_g1_i4,DN1097_c0_g1,NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},NGBR_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0001525^biological_process^angiogenesis,KEGG:hsa:116150`KO:K19177,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i13,DN391_c0_g1,CBX7_HUMAN,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^128-154^E:6.7e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i14,DN391_c0_g1,CBX7_HUMAN,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^128-154^E:6.7e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i5,DN391_c0_g1,CBX7_MOUSE,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^128-154^E:6.7e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i12,DN391_c0_g1,CBX7_MOUSE,Chromobox protein homolog 7,CBX7_MOUSE,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:52609`KO:K11454,ENOG410ZMH7^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^110-136^E:5.6e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i6,DN391_c0_g1,CBX7_HUMAN,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^45-94^E:3.1e-15,PF17218.3^CBX7_C^CBX family C-terminal motif^240-266^E:1.4e-10,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i11,DN391_c0_g1,CBX7_MOUSE,Chromobox protein homolog 7,CBX7_MOUSE,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:52609`KO:K11454,ENOG410ZMH7^Chromo (CHRromatin Organisation MOdifier) domain,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^45-94^E:2.2e-15,PF17218.3^CBX7_C^CBX family C-terminal motif^183-209^E:1e-10,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i7,DN391_c0_g1,CBX7_HUMAN,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^128-154^E:6.7e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i3,DN391_c0_g1,CBX7_MOUSE,Chromobox protein homolog 7,CBX7_MOUSE,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005829^cellular_component^cytosol,GO:0000792^cellular_component^heterochromatin,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:52609`KO:K11454,ENOG410ZMH7^Chromo (CHRromatin Organisation MOdifier) domain,PF17218.3^CBX7_C^CBX family C-terminal motif^110-136^E:5.6e-11,NA,NA,NA,NA,,
no,AD,SAT,DN391_c0_g1_i4,DN391_c0_g1,CBX7_HUMAN,Chromobox protein homolog 7,CBX7_HUMAN,Chromobox protein homolog 7,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0031519^cellular_component^PcG protein complex,KEGG:hsa:23492`KO:K11454,ENOG410YM4V^Chromo (CHRromatin Organisation MOdifier) domain,PF00385.24^Chromo^Chromo (CHRromatin Organisation MOdifier) domain^45-94^E:3.1e-15,PF17218.3^CBX7_C^CBX family C-terminal motif^240-266^E:1.4e-10,NA,NA,NA,,
no,AD,SAT,DN324_c0_g1_i4,DN324_c0_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN324_c0_g1_i5,DN324_c0_g1,RCBT1_MOUSE,RCC1 and BTB domain-containing protein 1,RCBT1_MOUSE,RCC1 and BTB domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,KEGG:mmu:71330`KO:K11494,COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^99-149^E:4.1e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^136-165^E:5.8e-11,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^152-202^E:5e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^189-218^E:1.2e-07,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^205-254^E:9.1e-15,,
no,AD,SAT,DN324_c0_g2_i1,DN324_c0_g2,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,PF00651.31^BTB^BTB/POZ domain^80-180^E:3.9e-20,NA,NA,NA,NA,,
no,AD,SAT,DN74025_c0_g1_i2,DN74025_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN39832_c0_g1_i1,DN39832_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN31738_c0_g2_i1,DN31738_c0_g2,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN31738_c0_g2_i2,DN31738_c0_g2,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN31738_c1_g1_i1,DN31738_c1_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i2,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i1,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i15,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,SAT1_CHICK,Diamine acetyltransferase 1,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i7,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,SAT1_CHICK,Diamine acetyltransferase 1,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,PF00583.25^Acetyltransf_1^Acetyltransferase (GNAT) family^24-122^E:1.5e-16,PF13508.7^Acetyltransf_7^Acetyltransferase (GNAT) domain^31-122^E:7.1e-08,PF13673.7^Acetyltransf_10^Acetyltransferase (GNAT) domain^45-126^E:2.6e-05,NA,NA,,
no,AD,SAT,DN768_c0_g1_i12,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i5,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,SAT1_CHICK,Diamine acetyltransferase 1,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i11,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,SAT1_CHICK,Diamine acetyltransferase 1,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i10,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,SAT1_CHICK,Diamine acetyltransferase 1,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i3,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN768_c0_g1_i8,DN768_c0_g1,SAT1_CHICK,Diamine acetyltransferase 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:gga:374006`KO:K00657,COG0454^acetyltransferase,.,NA,NA,NA,NA,,
no,AD,SAT,DN55243_c0_g1_i2,DN55243_c0_g1,BACD1_MOUSE,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0016604^cellular_component^nuclear body,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:233877`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN63469_c0_g1_i1,DN63469_c0_g1,BACD3_HUMAN,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033},.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017049^molecular_function^GTP-Rho binding,GO:0005112^molecular_function^Notch binding,.,NA,NA,NA,NA,KEGG:hsa:83892`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN2293_c0_g3_i1,DN2293_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC4_HUMAN,Probable E3 ubiquitin-protein ligase HERC4,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:hsa:26091`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-141^E:5.2e-35,NA,NA,NA,NA,,
no,AD,SAT,DN2293_c0_g3_i7,DN2293_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC4_HUMAN,Probable E3 ubiquitin-protein ligase HERC4,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0007283^biological_process^spermatogenesis,KEGG:hsa:26091`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^2-141^E:5.2e-35,NA,NA,NA,NA,,
no,AD,SAT,DN2293_c0_g3_i5,DN2293_c0_g3,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,KEGG:mmu:67345`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^133-356^E:2.1e-48,NA,NA,NA,NA,,
no,AD,SAT,DN2293_c0_g3_i3,DN2293_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^70-99^E:0.00019,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-115^E:1.7e-09,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^103-152^E:6.1e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^140-168^E:3.9e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^155-204^E:1.6e-15,,
no,AD,SAT,DN2293_c0_g3_i8,DN2293_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^70-99^E:0.00024,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-115^E:2.1e-09,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^103-152^E:7.8e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^140-168^E:4.9e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^155-204^E:2.1e-15,,
no,AD,SAT,DN2293_c0_g3_i9,DN2293_c0_g3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^70-99^E:0.00018,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^86-115^E:1.7e-09,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^103-152^E:6e-13,PF13540.6^RCC1_2^Regulator of chromosome condensation (RCC1) repeat^140-168^E:3.8e-08,PF00415.18^RCC1^Regulator of chromosome condensation (RCC1) repeat^155-204^E:1.6e-15,,
no,AD,SAT,DN2293_c0_g3_i11,DN2293_c0_g3,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,HERC4_MOUSE,Probable E3 ubiquitin-protein ligase HERC4,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0061630^molecular_function^ubiquitin protein ligase activity,GO:0004842^molecular_function^ubiquitin-protein transferase activity,GO:0030154^biological_process^cell differentiation,KEGG:mmu:67345`KO:K10615,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,PF00632.25^HECT^HECT-domain (ubiquitin-transferase)^95-175^E:2.9e-08,NA,NA,NA,NA,,
no,AD,SAT,DN62690_c0_g1_i1,DN62690_c0_g1,HERC2_HUMAN,E3 ubiquitin-protein ligase HERC2,.,NA,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:8924`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN17545_c0_g1_i1,DN17545_c0_g1,RCBT1_HUMAN,RCC1 and BTB domain-containing protein 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0007049^biological_process^cell cycle,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:55213`KO:K11494,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN59029_c0_g1_i1,DN59029_c0_g1,SATT_BOVIN,Neutral amino acid transporter A,SATT_BOVIN,Neutral amino acid transporter A,GO:0005813^cellular_component^centrosome,GO:0016021^cellular_component^integral component of membrane,GO:0005882^cellular_component^intermediate filament,GO:0042470^cellular_component^melanosome,GO:0005254^molecular_function^chloride channel activity,GO:0005813^cellular_component^centrosome,GO:0016021^cellular_component^integral component of membrane,GO:0005882^cellular_component^intermediate filament,GO:0042470^cellular_component^melanosome,GO:0005254^molecular_function^chloride channel activity,KEGG:bta:326577`KO:K05615,COG1301^sodium dicarboxylate symporter,PF00375.18^SDF^Sodium:dicarboxylate symporter family^2-75^E:3.7e-20,NA,NA,NA,NA,,
no,AD,SAT,DN34760_c0_g1_i2,DN34760_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN34760_c0_g1_i1,DN34760_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN15981_c0_g1_i3,DN15981_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN48489_c0_g1_i2,DN48489_c0_g1,NGB_BOVIN,Neuroglobin,.,NA,GO:0043204^cellular_component^perikaryon,GO:0020037^molecular_function^heme binding,GO:0046872^molecular_function^metal ion binding,GO:0019825^molecular_function^oxygen binding,GO:0005344^molecular_function^oxygen carrier activity,.,NA,NA,NA,NA,KEGG:bta:414920`KO:K21893,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",.,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i17,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_MOUSE,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:mmu:70099`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i12,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_HUMAN,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:10051`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^377-492^E:1.9e-23,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i14,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_HUMAN,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:10051`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^384-499^E:2e-23,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i3,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_MOUSE,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:mmu:70099`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i10,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_HUMAN,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:10051`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^377-492^E:2.1e-23,NA,NA,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i7,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_MOUSE,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:mmu:70099`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),PF02463.19^SMC_N^RecF/RecN/SMC N terminal domain^80-692^E:6.9e-29,PF13175.6^AAA_15^AAA ATPase domain^80-491^E:3.5e-09,PF06470.13^SMC_hinge^SMC proteins Flexible Hinge Domain^610-725^E:3.2e-23,NA,NA,,
no,AD,SAT,DN9355_c0_g1_i6,DN9355_c0_g1,SMC4_XENLA,Structural maintenance of chromosomes protein 4,SMC4_MOUSE,Structural maintenance of chromosomes protein 4,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,GO:0046982^molecular_function^protein heterodimerization activity,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0005524^molecular_function^ATP binding,KEGG:mmu:70099`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN1610_c3_g1_i10,DN1610_c3_g1,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),PF01255.19^Prenyltransf^Putative undecaprenyl diphosphate synthase^32-250^E:2.3e-77,NA,NA,NA,NA,,
no,AD,SAT,DN1610_c3_g1_i11,DN1610_c3_g1,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN1610_c3_g1_i1,DN1610_c3_g1,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),PF01255.19^Prenyltransf^Putative undecaprenyl diphosphate synthase^32-250^E:2.5e-77,NA,NA,NA,NA,,
no,AD,SAT,DN1610_c3_g1_i2,DN1610_c3_g1,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),PF01255.19^Prenyltransf^Putative undecaprenyl diphosphate synthase^32-250^E:4.8e-77,NA,NA,NA,NA,,
no,AD,SAT,DN1613_c0_g1_i1,DN1613_c0_g1,BACD3_HUMAN,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033},.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017049^molecular_function^GTP-Rho binding,GO:0005112^molecular_function^Notch binding,.,NA,NA,NA,NA,KEGG:hsa:83892`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN1613_c0_g1_i4,DN1613_c0_g1,BACD3_HUMAN,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033},BACD3_HUMAN,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033},GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017049^molecular_function^GTP-Rho binding,GO:0005112^molecular_function^Notch binding,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0017049^molecular_function^GTP-Rho binding,GO:0005112^molecular_function^Notch binding,KEGG:hsa:83892`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^54-144^E:1.9e-20,PF00651.31^BTB^BTB/POZ domain^75-151^E:0.00028,NA,NA,NA,,
no,AD,SAT,DN40353_c1_g1_i1,DN40353_c1_g1,RCCD1_HUMAN,RCC1 domain-containing protein 1,.,NA,GO:0005694^cellular_component^chromosome,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0006325^biological_process^chromatin organization,NA,.,NA,NA,NA,NA,KEGG:hsa:91433,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g1_i17,DN46812_c0_g1,KCD15_BOVIN,BTB/POZ domain-containing protein KCTD15,.,NA,GO:0042802^molecular_function^identical protein binding,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,.,NA,NA,NA,NA,KEGG:bta:512578`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g1_i21,DN46812_c0_g1,KC15L_DANRE,BTB/POZ domain-containing protein kctd15-like,.,NA,GO:0007420^biological_process^brain development,GO:0014033^biological_process^neural crest cell differentiation,GO:0014036^biological_process^neural crest cell fate specification,GO:0060037^biological_process^pharyngeal system development,GO:0051260^biological_process^protein homooligomerization,.,NA,NA,NA,NA,KEGG:dre:449991`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g1_i4,DN46812_c0_g1,KC15L_DANRE,BTB/POZ domain-containing protein kctd15-like,.,NA,GO:0007420^biological_process^brain development,GO:0014033^biological_process^neural crest cell differentiation,GO:0014036^biological_process^neural crest cell fate specification,GO:0060037^biological_process^pharyngeal system development,GO:0051260^biological_process^protein homooligomerization,.,NA,NA,NA,NA,KEGG:dre:449991`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g1_i8,DN46812_c0_g1,KC15L_DANRE,BTB/POZ domain-containing protein kctd15-like,.,NA,GO:0007420^biological_process^brain development,GO:0014033^biological_process^neural crest cell differentiation,GO:0014036^biological_process^neural crest cell fate specification,GO:0060037^biological_process^pharyngeal system development,GO:0051260^biological_process^protein homooligomerization,.,NA,NA,NA,NA,KEGG:dre:449991`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g2_i2,DN46812_c0_g2,KCD15_BOVIN,BTB/POZ domain-containing protein KCTD15,KCD15_BOVIN,BTB/POZ domain-containing protein KCTD15,GO:0042802^molecular_function^identical protein binding,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,GO:0042802^molecular_function^identical protein binding,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,KEGG:bta:512578`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^81-169^E:2.1e-16,NA,NA,NA,NA,,
no,AD,SAT,DN46812_c0_g2_i1,DN46812_c0_g2,KCD15_XENTR,BTB/POZ domain-containing protein kctd15,KCD15_XENTR,BTB/POZ domain-containing protein kctd15,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:xtr:394848`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^18-75^E:1.7e-09,NA,NA,NA,NA,,
no,AD,SAT,DN111463_c0_g1_i1,DN111463_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN190301_c0_g1_i1,DN190301_c0_g1,FADS1_RAT,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:rno:84575`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN192265_c0_g1_i1,DN192265_c0_g1,SMC3_RAT,Structural maintenance of chromosomes protein 3,.,NA,GO:0005604^cellular_component^basement membrane,GO:0000785^cellular_component^chromatin,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0030893^cellular_component^meiotic cohesin complex,GO:0097431^cellular_component^mitotic spindle pole,.,NA,NA,NA,NA,.,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN139825_c0_g2_i1,DN139825_c0_g2,DHDDS_HUMAN,Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305},.,NA,GO:1904423^cellular_component^dehydrodolichyl diphosphate synthase complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0045547^molecular_function^dehydrodolichyl diphosphate synthase activity,GO:0002094^molecular_function^polyprenyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:79947`KO:K11778,COG0020^Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN154792_c0_g1_i1,DN154792_c0_g1,SMC1B_MOUSE,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0000794^cellular_component^condensed nuclear chromosome,GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:mmu:140557`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN149100_c0_g1_i1,DN149100_c0_g1,IBTK_HUMAN,Inhibitor of Bruton tyrosine kinase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016020^cellular_component^membrane,GO:0005654^cellular_component^nucleoplasm,GO:0019901^molecular_function^protein kinase binding,GO:0030292^molecular_function^protein tyrosine kinase inhibitor activity,.,NA,NA,NA,NA,KEGG:hsa:25998,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN178761_c0_g1_i1,DN178761_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,.,NA,NA,NA,NA,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN116593_c0_g1_i1,DN116593_c0_g1,KCTD3_HUMAN,BTB/POZ domain-containing protein KCTD3,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:51133`KO:K21915,ENOG410XSWI^Potassium channel tetramerisation domain containing 3,.,NA,NA,NA,NA,,
no,AD,SAT,DN131989_c0_g2_i2,DN131989_c0_g2,FADS1_RAT,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:rno:84575`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN107838_c2_g1_i1,DN107838_c2_g1,KCTD5_HUMAN,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:hsa:54442`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN144488_c0_g1_i1,DN144488_c0_g1,KCTD7_CHICK,BTB/POZ domain-containing protein KCTD7,.,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0030007^biological_process^cellular potassium ion homeostasis,GO:0090461^biological_process^glutamate homeostasis,GO:0060081^biological_process^membrane hyperpolarization,.,NA,NA,NA,NA,KEGG:gga:417547`KO:K21917,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN128679_c0_g1_i2,DN128679_c0_g1,HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_MOUSE,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0009436^biological_process^glyoxylate catabolic process,KEGG:mmu:67432`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^15-63^E:5.5e-10,NA,NA,NA,NA,,
no,AD,SAT,DN125940_c0_g1_i1,DN125940_c0_g1,RCC1_XENLA,Regulator of chromosome condensation,.,NA,GO:0005694^cellular_component^chromosome,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005085^molecular_function^guanyl-nucleotide exchange factor activity,GO:0007049^biological_process^cell cycle,.,NA,NA,NA,NA,KEGG:xla:397722`KO:K11493,.,.,NA,NA,NA,NA,,
no,AD,SAT,DN148751_c0_g1_i1,DN148751_c0_g1,SMC2_MOUSE,Structural maintenance of chromosomes protein 2,.,NA,GO:0000793^cellular_component^condensed chromosome,GO:0000796^cellular_component^condensin complex,GO:0005737^cellular_component^cytoplasm,GO:0000228^cellular_component^nuclear chromosome,GO:0005730^cellular_component^nucleolus,.,NA,NA,NA,NA,KEGG:mmu:14211`KO:K06674,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN132955_c0_g1_i1,DN132955_c0_g1,KCTD4_MOUSE,BTB/POZ domain-containing protein KCTD4,KCTD4_MOUSE,BTB/POZ domain-containing protein KCTD4,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,KEGG:mmu:67516,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^11-61^E:4.8e-09,NA,NA,NA,NA,,
no,AD,SAT,DN186774_c0_g1_i1,DN186774_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN107344_c0_g1_i2,DN107344_c0_g1,FADS2_DANRE,Fatty acid desaturase 2,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0001889^biological_process^liver development,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,.,NA,NA,NA,NA,KEGG:dre:140615`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN156342_c0_g1_i1,DN156342_c0_g1,KCTD2_HUMAN,BTB/POZ domain-containing protein KCTD2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0097602^molecular_function^cullin family protein binding,GO:0044877^molecular_function^protein-containing complex binding,GO:0043161^biological_process^proteasome-mediated ubiquitin-dependent protein catabolic process,.,NA,NA,NA,NA,KEGG:hsa:23510`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN119848_c0_g1_i1,DN119848_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN119856_c0_g1_i2,DN119856_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN119856_c0_g1_i1,DN119856_c0_g1,FADS1_HUMAN,Acyl-CoA (8-3)-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005739^cellular_component^mitochondrion,.,NA,NA,NA,NA,KEGG:hsa:3992`KO:K10224,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN161723_c0_g1_i1,DN161723_c0_g1,SCD5_BOVIN,Stearoyl-CoA desaturase 5,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005506^molecular_function^iron ion binding,GO:0016491^molecular_function^oxidoreductase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,.,NA,NA,NA,NA,KEGG:bta:617419`KO:K00507,COG1398^desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN287642_c0_g1_i1,DN287642_c0_g1,SCD1_TACFU,Acyl-CoA desaturase 1 {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0046872^molecular_function^metal ion binding,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,GO:0006633^biological_process^fatty acid biosynthetic process,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,SAT,DN206789_c0_g1_i1,DN206789_c0_g1,FADS2_TACFU,Fatty acid desaturase 2 {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0006636^biological_process^unsaturated fatty acid biosynthetic process,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,SAT,DN297139_c0_g1_i1,DN297139_c0_g1,HERC2_MOUSE,E3 ubiquitin-protein ligase HERC2,.,NA,GO:0005814^cellular_component^centriole,GO:0005737^cellular_component^cytoplasm,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005634^cellular_component^nucleus,GO:0032183^molecular_function^SUMO binding,.,NA,NA,NA,NA,KEGG:mmu:15204`KO:K10595,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN256728_c0_g1_i1,DN256728_c0_g1,SMC1B_HUMAN,Structural maintenance of chromosomes protein 1B,.,NA,"GO:0000775^cellular_component^chromosome, centromeric region",GO:0005829^cellular_component^cytosol,GO:0000800^cellular_component^lateral element,GO:0030893^cellular_component^meiotic cohesin complex,GO:0034991^cellular_component^nuclear meiotic cohesin complex,.,NA,NA,NA,NA,KEGG:hsa:27127`KO:K06636,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN295701_c0_g1_i1,DN295701_c0_g1,BACD2_XENTR,BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0017049^molecular_function^GTP-Rho binding,.,NA,NA,NA,NA,KEGG:xtr:549563`KO:K15074,ENOG410XQYZ^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN238816_c0_g1_i1,DN238816_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN208235_c0_g1_i1,DN208235_c0_g1,SRGEF_HUMAN,Secretion-regulating guanine nucleotide exchange factor,.,NA,GO:0016235^cellular_component^aggresome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:26297`KO:K15421,COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN388976_c0_g1_i1,DN388976_c0_g1,HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",HOGA1_HUMAN,"4-hydroxy-2-oxoglutarate aldolase, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0008700^molecular_function^4-hydroxy-2-oxoglutarate aldolase activity,GO:0042803^molecular_function^protein homodimerization activity,GO:0019470^biological_process^4-hydroxyproline catabolic process,KEGG:hsa:112817`KO:K18123,COG0329^Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity),PF00701.22^DHDPS^Dihydrodipicolinate synthetase family^32-79^E:1.6e-05,NA,NA,NA,NA,,
no,AD,SAT,DN382915_c0_g1_i1,DN382915_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN392622_c0_g1_i1,DN392622_c0_g1,KCD16_HUMAN,BTB/POZ domain-containing protein KCTD16,KCD16_HUMAN,BTB/POZ domain-containing protein KCTD16,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0051260^biological_process^protein homooligomerization,NA,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0051260^biological_process^protein homooligomerization,NA,KEGG:hsa:57528`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,PF02214.22^BTB_2^BTB/POZ domain^18-109^E:7.5e-16,NA,NA,NA,NA,,
no,AD,SAT,DN387028_c0_g1_i1,DN387028_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN313968_c0_g1_i1,DN313968_c0_g1,CYGB_HUMAN,Cytoglobin,.,NA,GO:0005829^cellular_component^cytosol,GO:0043005^cellular_component^neuron projection,GO:0043025^cellular_component^neuronal cell body,GO:0016607^cellular_component^nuclear speck,GO:0004096^molecular_function^catalase activity,.,NA,NA,NA,NA,KEGG:hsa:114757`KO:K21894,"COG1018^Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)",.,NA,NA,NA,NA,,
no,AD,SAT,DN305268_c0_g1_i1,DN305268_c0_g1,MSTO1_BOVIN,Protein misato homolog 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005741^cellular_component^mitochondrial outer membrane,GO:0000002^biological_process^mitochondrial genome maintenance,GO:0048311^biological_process^mitochondrion distribution,GO:0007005^biological_process^mitochondrion organization,.,NA,NA,NA,NA,KEGG:bta:535567,ENOG410XPM0^Misato homolog 1 (Drosophila),.,NA,NA,NA,NA,,
no,AD,SAT,DN339767_c0_g1_i1,DN339767_c0_g1,KCTD4_MOUSE,BTB/POZ domain-containing protein KCTD4,.,NA,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:67516,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN341569_c0_g1_i1,DN341569_c0_g1,HERC3_HUMAN,Probable E3 ubiquitin-protein ligase HERC3,.,NA,GO:0031410^cellular_component^cytoplasmic vesicle,GO:0005829^cellular_component^cytosol,GO:0004842^molecular_function^ubiquitin-protein transferase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:8916`KO:K10614,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN442712_c0_g1_i1,DN442712_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN437854_c0_g1_i1,DN437854_c0_g1,FADS2_RAT,Acyl-CoA 6-desaturase {ECO:0000305},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016213^molecular_function^linoleoyl-CoA desaturase activity,GO:0045485^molecular_function^omega-6 fatty acid desaturase activity,GO:0004768^molecular_function^stearoyl-CoA 9-desaturase activity,.,NA,NA,NA,NA,KEGG:rno:83512`KO:K10226,ENOG410XVSZ^Fatty acid desaturase,.,NA,NA,NA,NA,,
no,AD,SAT,DN410400_c0_g1_i1,DN410400_c0_g1,SMC4_HUMAN,Structural maintenance of chromosomes protein 4,.,NA,GO:0000796^cellular_component^condensin complex,GO:0005829^cellular_component^cytosol,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:10051`KO:K06675,COG1196^Required for chromosome condensation and partitioning (By similarity),.,NA,NA,NA,NA,,
no,AD,SAT,DN447690_c0_g1_i1,DN447690_c0_g1,KCD15_XENTR,BTB/POZ domain-containing protein kctd15,KCD15_XENTR,BTB/POZ domain-containing protein kctd15,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,GO:0007275^biological_process^multicellular organism development,GO:0051260^biological_process^protein homooligomerization,NA,NA,NA,KEGG:xtr:394848`KO:K21754,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN469546_c0_g1_i1,DN469546_c0_g1,SAT2_BOVIN,Diamine acetyltransferase 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0004145^molecular_function^diamine N-acetyltransferase activity,GO:0042802^molecular_function^identical protein binding,GO:0008080^molecular_function^N-acetyltransferase activity,GO:0019809^molecular_function^spermidine binding,.,NA,NA,NA,NA,KEGG:bta:359722`KO:K00657,ENOG4111PFJ^spermidine spermine N1-acetyltransferase family member 2,.,NA,NA,NA,NA,,
no,AD,SAT,DN414051_c0_g1_i1,DN414051_c0_g1,HERC1_HUMAN,Probable E3 ubiquitin-protein ligase HERC1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016020^cellular_component^membrane,GO:0005086^molecular_function^ARF guanyl-nucleotide exchange factor activity,.,NA,NA,NA,NA,KEGG:hsa:8925`KO:K10594,COG5021^ubiquitin protein ligase`COG5184^regulator of chromosome condensation,.,NA,NA,NA,NA,,
no,AD,SAT,DN470494_c0_g1_i1,DN470494_c0_g1,KCD16_HUMAN,BTB/POZ domain-containing protein KCTD16,.,NA,GO:0030054^cellular_component^cell junction,GO:0045211^cellular_component^postsynaptic membrane,GO:0042734^cellular_component^presynaptic membrane,GO:0051260^biological_process^protein homooligomerization,NA,.,NA,NA,NA,NA,KEGG:hsa:57528`KO:K21918,ENOG410Z155^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
no,AD,SAT,DN401737_c0_g1_i1,DN401737_c0_g1,KCTD5_BOVIN,BTB/POZ domain-containing protein KCTD5,.,NA,GO:0031463^cellular_component^Cul3-RING ubiquitin ligase complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0097602^molecular_function^cullin family protein binding,.,NA,NA,NA,NA,KEGG:bta:100125308`KO:K21914,ENOG410XT4J^potassium channel tetramerisation domain containing,.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i1,DN2336_c0_g1,SEPP1_HUMAN,Selenoprotein P {ECO:0000303|PubMed:27645994},.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0031089^cellular_component^platelet dense granule lumen,GO:0008430^molecular_function^selenium binding,.,NA,NA,NA,NA,KEGG:hsa:6414,"ENOG4111JK7^selenoprotein P, plasma, 1",.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i10,DN2336_c0_g1,SEPP1_RAT,Selenoprotein P {ECO:0000303|PubMed:2037562},.,NA,GO:0005615^cellular_component^extracellular space,GO:0008430^molecular_function^selenium binding,GO:0010269^biological_process^response to selenium ion,GO:0001887^biological_process^selenium compound metabolic process,NA,.,NA,NA,NA,NA,KEGG:rno:29360,.,.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i6,DN2336_c0_g1,SEPP1_RAT,Selenoprotein P {ECO:0000303|PubMed:2037562},.,NA,GO:0005615^cellular_component^extracellular space,GO:0008430^molecular_function^selenium binding,GO:0010269^biological_process^response to selenium ion,GO:0001887^biological_process^selenium compound metabolic process,NA,.,NA,NA,NA,NA,KEGG:rno:29360,.,.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i7,DN2336_c0_g1,SEPP1_HUMAN,Selenoprotein P {ECO:0000303|PubMed:27645994},.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0031089^cellular_component^platelet dense granule lumen,GO:0008430^molecular_function^selenium binding,.,NA,NA,NA,NA,KEGG:hsa:6414,"ENOG4111JK7^selenoprotein P, plasma, 1",.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i9,DN2336_c0_g1,SEPP1_HUMAN,Selenoprotein P {ECO:0000303|PubMed:27645994},.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0031089^cellular_component^platelet dense granule lumen,GO:0008430^molecular_function^selenium binding,.,NA,NA,NA,NA,KEGG:hsa:6414,"ENOG4111JK7^selenoprotein P, plasma, 1",.,NA,NA,NA,NA,,
yes,AD,SEPP,DN2336_c0_g1_i5,DN2336_c0_g1,SEPP1_RAT,Selenoprotein P {ECO:0000303|PubMed:2037562},.,NA,GO:0005615^cellular_component^extracellular space,GO:0008430^molecular_function^selenium binding,GO:0010269^biological_process^response to selenium ion,GO:0001887^biological_process^selenium compound metabolic process,NA,.,NA,NA,NA,NA,KEGG:rno:29360,.,.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN4778_c0_g1_i5,DN4778_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,KEGG:ptr:456832`KO:K00781,.,PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^93-354^E:3e-70,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN4778_c0_g1_i4,DN4778_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,KEGG:ptr:456832`KO:K00781,.,PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^151-412^E:4.7e-70,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN4778_c0_g1_i1,DN4778_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:456832`KO:K00781,.,.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g1_i4,DN3871_c0_g1,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^139-359^E:3.6e-36,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g1_i2,DN3871_c0_g1,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^139-207^E:1.5e-21,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g1_i3,DN3871_c0_g1,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^65-282^E:4.1e-36,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g1_i6,DN3871_c0_g1,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g2_i1,DN3871_c0_g2,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g2_i2,DN3871_c0_g2,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^2-66^E:1.3e-21,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3871_c0_g4_i1,DN3871_c0_g4,SIA7E_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006688^biological_process^glycosphingolipid biosynthetic process,.,NA,NA,NA,NA,KEGG:hsa:81849`KO:K03375,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i6,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i5,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^66-192^E:1e-20,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i2,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^66-190^E:1.1e-20,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i1,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^66-190^E:1.1e-20,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i4,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i3,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^66-190^E:1.1e-20,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN2928_c0_g1_i8,DN2928_c0_g1,SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",SIA7F_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0005737^cellular_component^cytoplasm,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:30815`KO:K03376,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^66-229^E:1.6e-31,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN454_c0_g1_i8,DN454_c0_g1,SIAT9_BOVIN,"Lactosylceramide alpha-2,3-sialyltransferase",SIAT9_PANTR,"Lactosylceramide alpha-2,3-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,KEGG:ptr:459371`KO:K03370,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^94-168^E:3.5e-16,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN454_c0_g1_i2,DN454_c0_g1,SIAT9_BOVIN,"Lactosylceramide alpha-2,3-sialyltransferase",SIAT9_PANTR,"Lactosylceramide alpha-2,3-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,KEGG:ptr:459371`KO:K03370,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^94-231^E:1.6e-37,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN454_c0_g1_i1,DN454_c0_g1,SIAT9_PANTR,"Lactosylceramide alpha-2,3-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:ptr:459371`KO:K03370,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN454_c0_g1_i4,DN454_c0_g1,SIAT9_BOVIN,"Lactosylceramide alpha-2,3-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047291^molecular_function^lactosylceramide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:bta:404164`KO:K03370,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN42605_c0_g1_i4,DN42605_c0_g1,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15454_c0_g1_i2,DN15454_c0_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15589_c0_g1_i2,DN15589_c0_g1,SIA7C_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",SIA7C_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005654^cellular_component^nucleoplasm,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity","GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005654^cellular_component^nucleoplasm,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity","GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:256435`KO:K03373,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^2-208^E:1.8e-28,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15589_c0_g1_i3,DN15589_c0_g1,SIA7C_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",SIA7C_HUMAN,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005654^cellular_component^nucleoplasm,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity","GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005654^cellular_component^nucleoplasm,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity","GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",KEGG:hsa:256435`KO:K03373,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^72-296^E:4.6e-36,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15555_c0_g1_i15,DN15555_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:456832`KO:K00781,.,.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15555_c0_g1_i16,DN15555_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:456832`KO:K00781,.,.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN15555_c0_g1_i8,DN15555_c0_g1,SIAT6_RAT,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:rno:64445`KO:K00781,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN5182_c0_g1_i8,DN5182_c0_g1,SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,KEGG:hsa:27090`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^56-287^E:4.8e-36,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN5182_c0_g1_i1,DN5182_c0_g1,SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,.,NA,NA,NA,NA,KEGG:hsa:27090`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN5182_c0_g1_i3,DN5182_c0_g1,SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,.,NA,NA,NA,NA,KEGG:hsa:27090`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN5182_c0_g1_i6,DN5182_c0_g1,SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,.,NA,NA,NA,NA,KEGG:hsa:27090`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN5182_c0_g1_i16,DN5182_c0_g1,SIA7D_MOUSE,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:mmu:20448`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i12,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^318-528^E:6.5e-38,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i7,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i3,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^51-157^E:4.9e-13,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i13,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^430-640^E:9.6e-38,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i8,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^362-572^E:7.6e-38,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i2,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^318-528^E:6.5e-38,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN21079_c0_g1_i1,DN21079_c0_g1,SIAT2_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 2",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,NA,.,NA,NA,NA,NA,KEGG:gga:403122`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN95432_c0_g1_i1,DN95432_c0_g1,SIA4C_HUMAN,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_HUMAN,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,KEGG:hsa:6484`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^1-140^E:1.1e-27,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3612_c1_g1_i7,DN3612_c1_g1,SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:mmu:20444`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^94-255^E:2.5e-43,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3612_c1_g1_i1,DN3612_c1_g1,SIA4B_HUMAN,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_HUMAN,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",KEGG:hsa:6483`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^88-319^E:3.1e-79,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3612_c1_g1_i2,DN3612_c1_g1,SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:mmu:20444`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^94-346^E:1.3e-80,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3612_c1_g1_i4,DN3612_c1_g1,SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:20444`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i1,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^151-396^E:6.4e-65,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i12,DN8528_c0_g1,SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:mmu:20443`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i13,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i15,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i14,DN8528_c0_g1,SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i4,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i8,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^112-357^E:4.7e-65,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i2,DN8528_c0_g1,SIA4C_PANTR,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:466845`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i17,DN8528_c0_g1,SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",KEGG:mmu:20443`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^45-229^E:6.1e-46,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i9,DN8528_c0_g1,SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",KEGG:mmu:20443`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^1-197^E:4e-52,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8528_c0_g1_i11,DN8528_c0_g1,SIA4C_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:mmu:20443`KO:K03494,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13484_c0_g1_i4,DN13484_c0_g1,SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,KEGG:ptr:461971`KO:K06614,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^96-168^E:7.8e-22,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13484_c0_g1_i1,DN13484_c0_g1,SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,KEGG:ptr:461971`KO:K06614,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^96-256^E:1.7e-45,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13484_c0_g1_i2,DN13484_c0_g1,SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,.,NA,NA,NA,NA,KEGG:ptr:461971`KO:K06614,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13484_c0_g1_i3,DN13484_c0_g1,SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,KEGG:ptr:461971`KO:K06614,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^96-353^E:3.4e-77,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i16,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^3-85^E:2.2e-26,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i6,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,.,NA,NA,NA,NA,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i3,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,.,NA,NA,NA,NA,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i12,DN7946_c0_g1,SIA7B_MOUSE,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",SIA7B_MOUSE,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006493^biological_process^protein O-linked glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006493^biological_process^protein O-linked glycosylation,KEGG:mmu:20446`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^2-150^E:1.9e-37,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i14,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,.,NA,NA,NA,NA,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i15,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^29-192^E:2.9e-39,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i7,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^273-465^E:1.6e-39,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g1_i13,DN7946_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^29-280^E:1.8e-69,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7946_c0_g2_i2,DN7946_c0_g2,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,.,NA,NA,NA,NA,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN52723_c0_g1_i1,DN52723_c0_g1,SIA10_PONAB,"Type 2 lactosamine alpha-2,3-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0052798^molecular_function^beta-galactoside alpha-2,3-sialyltransferase activity",GO:0006464^biological_process^cellular protein modification process,GO:0071354^biological_process^cellular response to interleukin-6,.,NA,NA,NA,NA,KEGG:pon:100171770`KO:K03792,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN85253_c0_g1_i1,DN85253_c0_g1,SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",KEGG:hsa:8128`KO:K06612,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^135-269^E:6.2e-41,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN85253_c0_g1_i2,DN85253_c0_g1,SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",KEGG:hsa:8128`KO:K06612,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^89-223^E:3.8e-41,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN85253_c0_g1_i3,DN85253_c0_g1,SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",SIA8B_HUMAN,"Alpha-2,8-sialyltransferase 8B",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0005769^cellular_component^early endosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0055037^cellular_component^recycling endosome,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",KEGG:hsa:8128`KO:K06612,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^92-226^E:3.9e-41,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN25700_c0_g1_i2,DN25700_c0_g1,SIA8E_HUMAN,"Alpha-2,8-sialyltransferase 8E",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005975^biological_process^carbohydrate metabolic process,.,NA,NA,NA,NA,KEGG:hsa:29906`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN4385_c0_g2_i5,DN4385_c0_g2,SIA10_HUMAN,"Type 2 lactosamine alpha-2,3-sialyltransferase",.,NA,GO:0070062^cellular_component^extracellular exosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0052798^molecular_function^beta-galactoside alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:10402`KO:K03792,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN4385_c0_g2_i6,DN4385_c0_g2,SIA10_HUMAN,"Type 2 lactosamine alpha-2,3-sialyltransferase",SIA10_HUMAN,"Type 2 lactosamine alpha-2,3-sialyltransferase",GO:0070062^cellular_component^extracellular exosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0052798^molecular_function^beta-galactoside alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0070062^cellular_component^extracellular exosome,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0052798^molecular_function^beta-galactoside alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,KEGG:hsa:10402`KO:K03792,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^106-348^E:2.2e-65,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13002_c0_g1_i3,DN13002_c0_g1,SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,KEGG:gga:396140`KO:K00780,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^85-287^E:4.7e-62,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13002_c0_g1_i2,DN13002_c0_g1,SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,KEGG:gga:396140`KO:K00780,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^85-339^E:6.2e-80,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN13002_c0_g1_i1,DN13002_c0_g1,SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,KEGG:gga:396140`KO:K00780,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^85-339^E:6.2e-80,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN18849_c2_g3_i1,DN18849_c2_g3,SIA8A_BOVIN,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",SIA8A_BOVIN,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,KEGG:bta:282352`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN10666_c0_g1_i1,DN10666_c0_g1,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7287_c2_g1_i9,DN7287_c2_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN7287_c2_g1_i7,DN7287_c2_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN18456_c0_g1_i10,DN18456_c0_g1,SIA8C_HUMAN,"Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0042802^molecular_function^identical protein binding,GO:0033691^molecular_function^sialic acid binding,.,NA,NA,NA,NA,KEGG:hsa:51046`KO:K06613,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN18456_c0_g1_i6,DN18456_c0_g1,SIA8C_HUMAN,"Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0042802^molecular_function^identical protein binding,GO:0033691^molecular_function^sialic acid binding,.,NA,NA,NA,NA,KEGG:hsa:51046`KO:K06613,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN1762_c0_g1_i3,DN1762_c0_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN1762_c0_g1_i8,DN1762_c0_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF01442.18^Apolipoprotein^Apolipoprotein A1/A4/E domain^138-209^E:0.018,PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^369-457^E:1.9e-18,NA,NA,NA,,
yes,AD,sialyltransferase,DN1762_c0_g1_i7,DN1762_c0_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN1762_c0_g2_i1,DN1762_c0_g2,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN31441_c0_g1_i3,DN31441_c0_g1,SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",SIA7A_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0009312^biological_process^oligosaccharide biosynthetic process,GO:0006486^biological_process^protein glycosylation,KEGG:gga:396168`KO:K03479,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN53401_c1_g1_i1,DN53401_c1_g1,SIAT2_BOVIN,"Beta-galactoside alpha-2,6-sialyltransferase 2",.,NA,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0005975^biological_process^carbohydrate metabolic process,GO:0006486^biological_process^protein glycosylation,.,NA,NA,NA,NA,KEGG:bta:493992`KO:K00779,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN537_c0_g4_i1,DN537_c0_g4,SIA8A_PANTR,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",SIA8A_PANTR,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,KEGG:ptr:465341`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^101-352^E:2e-78,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g1_i1,DN539_c0_g1,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i5,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^15-84^E:2.9e-09,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i11,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^170-392^E:4.3e-37,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i6,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i8,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^170-242^E:5.2e-22,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i4,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^15-84^E:2.9e-09,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g2_i3,DN539_c0_g2,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN539_c0_g3_i1,DN539_c0_g3,SIAT1_CHICK,"Beta-galactoside alpha-2,6-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003835^molecular_function^beta-galactoside alpha-2,6-sialyltransferase activity",.,NA,NA,NA,NA,KEGG:gga:396169`KO:K00778,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8806_c0_g1_i4,DN8806_c0_g1,SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:hsa:338596`KO:K06615,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^144-396^E:5.1e-79,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8806_c0_g1_i3,DN8806_c0_g1,SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:hsa:338596`KO:K06615,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^144-396^E:5.1e-79,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN8806_c0_g1_i1,DN8806_c0_g1,SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",SIA8F_HUMAN,"Alpha-2,8-sialyltransferase 8F",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0001835^biological_process^blastocyst hatching,GO:0016051^biological_process^carbohydrate biosynthetic process,KEGG:hsa:338596`KO:K06615,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^144-396^E:5.1e-79,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN59826_c0_g1_i3,DN59826_c0_g1,SIA4A_CHICK,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,.,NA,NA,NA,NA,KEGG:gga:396140`KO:K00780,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3366_c0_g1_i3,DN3366_c0_g1,SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,KEGG:ptr:455402`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^153-406^E:6.4e-78,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3366_c0_g1_i4,DN3366_c0_g1,SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,KEGG:ptr:455402`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^117-370^E:4.9e-78,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN3366_c0_g1_i2,DN3366_c0_g1,SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,KEGG:ptr:455402`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^153-406^E:6.4e-78,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN75962_c0_g1_i2,DN75962_c0_g1,SIA7B_CHICK,"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0001665^molecular_function^alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",GO:0006493^biological_process^protein O-linked glycosylation,GO:1990743^biological_process^protein sialylation,.,NA,NA,NA,NA,KEGG:gga:396159`KO:K06616,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN366_c1_g1_i4,DN366_c1_g1,SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:rno:64442`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN366_c1_g1_i3,DN366_c1_g1,SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_MOUSE,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0047288^molecular_function^monosialoganglioside sialyltransferase activity,KEGG:mmu:20444`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^53-116^E:1.7e-15,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN366_c1_g1_i1,DN366_c1_g1,SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,KEGG:rno:64442`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^87-323^E:1.2e-74,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN366_c1_g1_i7,DN366_c1_g1,SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",SIA4B_RAT,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2",GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,KEGG:rno:64442`KO:K03368,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^87-214^E:2.3e-37,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN23064_c0_g1_i2,DN23064_c0_g1,SIA4A_PIG,"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003836^molecular_function^beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",GO:0006054^biological_process^N-acetylneuraminate metabolic process,.,NA,NA,NA,NA,KEGG:ssc:445537`KO:K00780,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN155023_c0_g1_i1,DN155023_c0_g1,SIAT6_RAT,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:rno:64445`KO:K00781,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN113726_c0_g1_i3,DN113726_c0_g1,SIA8A_MOUSE,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0034605^biological_process^cellular response to heat,.,NA,NA,NA,NA,KEGG:mmu:20449`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN156618_c0_g1_i1,DN156618_c0_g1,SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,.,NA,NA,NA,NA,KEGG:ptr:455402`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN176981_c0_g1_i1,DN176981_c0_g1,SIA7D_HUMAN,"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0047290^molecular_function^(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0006664^biological_process^glycolipid metabolic process,.,NA,NA,NA,NA,KEGG:hsa:27090`KO:K03374,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN166103_c0_g1_i1,DN166103_c0_g1,SIA8A_MOUSE,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,GO:0034605^biological_process^cellular response to heat,.,NA,NA,NA,NA,KEGG:mmu:20449`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN214029_c0_g1_i1,DN214029_c0_g1,SIA8A_BOVIN,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,.,NA,NA,NA,NA,KEGG:bta:282352`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN244154_c0_g1_i1,DN244154_c0_g1,SIA8D_PANTR,"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0001574^biological_process^ganglioside biosynthetic process,GO:0006491^biological_process^N-glycan processing,.,NA,NA,NA,NA,KEGG:ptr:461971`KO:K06614,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN280455_c0_g1_i1,DN280455_c0_g1,SIA8B_RAT,"Alpha-2,8-sialyltransferase 8B",SIA8B_RAT,"Alpha-2,8-sialyltransferase 8B",GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,KEGG:rno:117523`KO:K06612,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",PF00777.18^Glyco_transf_29^Glycosyltransferase family 29 (sialyltransferase)^6-108^E:6.2e-28,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN205731_c0_g1_i1,DN205731_c0_g1,SIA8E_PANTR,"Alpha-2,8-sialyltransferase 8E",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0008373^molecular_function^sialyltransferase activity,GO:0006486^biological_process^protein glycosylation,NA,.,NA,NA,NA,NA,KEGG:ptr:455402`KO:K03369,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN242180_c0_g1_i2,DN242180_c0_g1,SIAT6_PANTR,"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase",.,NA,GO:0005576^cellular_component^extracellular region,GO:0032580^cellular_component^Golgi cisterna membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0008118^molecular_function^N-acetyllactosaminide alpha-2,3-sialyltransferase activity",GO:0008373^molecular_function^sialyltransferase activity,.,NA,NA,NA,NA,KEGG:ptr:456832`KO:K00781,.,.,NA,NA,NA,NA,,
yes,AD,sialyltransferase,DN448843_c0_g1_i1,DN448843_c0_g1,SIA8A_BOVIN,"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase",.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,"GO:0003828^molecular_function^alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",GO:0006486^biological_process^protein glycosylation,GO:0006665^biological_process^sphingolipid metabolic process,.,NA,NA,NA,NA,KEGG:bta:282352`KO:K03371,"ENOG410XT8P^ST3 beta-galactoside alpha-2,3-sialyltransferase",.,NA,NA,NA,NA,,
yes,AD,SLC35,DN19387_c0_g2_i1,DN19387_c0_g2,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,.,NA,NA,NA,NA,KEGG:pon:100174008`KO:K15274,COG0697^membrane,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN2336_c1_g1_i2,DN2336_c1_g1,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,KEGG:pon:100174008`KO:K15274,COG0697^membrane,PF04142.15^Nuc_sug_transp^Nucleotide-sugar transporter^1-285^E:8.7e-39,NA,NA,NA,NA,,
yes,AD,SLC35,DN2336_c1_g1_i5,DN2336_c1_g1,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,KEGG:pon:100174008`KO:K15274,COG0697^membrane,PF04142.15^Nuc_sug_transp^Nucleotide-sugar transporter^27-380^E:9.4e-49,PF00892.20^EamA^EamA-like transporter family^105-165^E:3.1e-06,NA,NA,NA,,
yes,AD,SLC35,DN3098_c0_g1_i1,DN3098_c0_g1,S35U4_HUMAN,SLC35A4 upstream open reading frame protein {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0032056^biological_process^positive regulation of translation in response to stress,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN3098_c0_g1_i2,DN3098_c0_g1,S35U4_HUMAN,SLC35A4 upstream open reading frame protein {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0032056^biological_process^positive regulation of translation in response to stress,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN3098_c0_g2_i7,DN3098_c0_g2,S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,KEGG:xtr:100124906`KO:K15273,COG0697^membrane,PF04142.15^Nuc_sug_transp^Nucleotide-sugar transporter^52-318^E:2.4e-43,NA,NA,NA,NA,,
yes,AD,SLC35,DN3098_c0_g2_i3,DN3098_c0_g2,S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,KEGG:xtr:100124906`KO:K15273,COG0697^membrane,PF04142.15^Nuc_sug_transp^Nucleotide-sugar transporter^52-318^E:2.4e-43,NA,NA,NA,NA,,
yes,AD,SLC35,DN3098_c0_g2_i2,DN3098_c0_g2,S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},S35A4_XENTR,Probable UDP-sugar transporter protein SLC35A4 {ECO:0000305},GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,GO:0005794^cellular_component^Golgi apparatus,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0015136^molecular_function^sialic acid transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,KEGG:xtr:100124906`KO:K15273,COG0697^membrane,PF04142.15^Nuc_sug_transp^Nucleotide-sugar transporter^52-318^E:2.4e-43,NA,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i7,DN9532_c0_g1,S35F3_MOUSE,Putative thiamine transporter SLC35F3 {ECO:0000250|UniProtKB:Q8IY50},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:210027`KO:K15288,ENOG4110PN8^solute carrier family 35 member,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i11,DN9532_c0_g1,S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},S35F3_MOUSE,Putative thiamine transporter SLC35F3 {ECO:0000250|UniProtKB:Q8IY50},GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,KEGG:mmu:210027`KO:K15288,ENOG4110PN8^solute carrier family 35 member,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i9,DN9532_c0_g1,S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,KEGG:hsa:148641`KO:K15288,ENOG4110PN8^solute carrier family 35 member,PF00892.20^EamA^EamA-like transporter family^37-97^E:5.6e-07,PF06027.12^SLC35F^Solute carrier family 35^37-246^E:1.1e-05,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i5,DN9532_c0_g1,S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,KEGG:hsa:148641`KO:K15288,ENOG4110PN8^solute carrier family 35 member,PF00892.20^EamA^EamA-like transporter family^222-376^E:1.7e-07,PF06027.12^SLC35F^Solute carrier family 35^316-525^E:6e-05,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i12,DN9532_c0_g1,S35F3_MOUSE,Putative thiamine transporter SLC35F3 {ECO:0000250|UniProtKB:Q8IY50},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:210027`KO:K15288,ENOG4110PN8^solute carrier family 35 member,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i10,DN9532_c0_g1,S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,KEGG:hsa:148641`KO:K15288,ENOG4110PN8^solute carrier family 35 member,PF00892.20^EamA^EamA-like transporter family^44-198^E:1.2e-07,PF06027.12^SLC35F^Solute carrier family 35^138-347^E:2.5e-05,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i2,DN9532_c0_g1,S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},S35F3_HUMAN,Putative thiamine transporter SLC35F3 {ECO:0000305},GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,KEGG:hsa:148641`KO:K15288,ENOG4110PN8^solute carrier family 35 member,PF00892.20^EamA^EamA-like transporter family^91-245^E:1.2e-07,PF06027.12^SLC35F^Solute carrier family 35^185-394^E:3.3e-05,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g1_i3,DN9532_c0_g1,S35F3_MOUSE,Putative thiamine transporter SLC35F3 {ECO:0000250|UniProtKB:Q8IY50},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:210027`KO:K15288,ENOG4110PN8^solute carrier family 35 member,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN9532_c0_g2_i1,DN9532_c0_g2,S35F3_MOUSE,Putative thiamine transporter SLC35F3 {ECO:0000250|UniProtKB:Q8IY50},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0015888^biological_process^thiamine transport,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:210027`KO:K15288,ENOG4110PN8^solute carrier family 35 member,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN32441_c1_g1_i1,DN32441_c1_g1,S35A5_PONAB,Probable UDP-sugar transporter protein SLC35A5,.,NA,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015165^molecular_function^pyrimidine nucleotide-sugar transmembrane transporter activity,GO:0008643^biological_process^carbohydrate transport,NA,.,NA,NA,NA,NA,KEGG:pon:100174008`KO:K15274,COG0697^membrane,.,NA,NA,NA,NA,,
yes,AD,SLC35,DN116491_c0_g1_i1,DN116491_c0_g1,S35U4_HUMAN,SLC35A4 upstream open reading frame protein {ECO:0000305},.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0032056^biological_process^positive regulation of translation in response to stress,NA,NA,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,MJ,ST3,DN7_c0_g1_i5,DN7_c0_g1,MAST3_XENLA,Microtubule-associated serine/threonine-protein kinase 3,.,NA,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:xla:447257`KO:K08789,.,.,NA,NA,NA,NA,,
no,MJ,ST3,DN7_c0_g1_i4,DN7_c0_g1,MAST3_XENLA,Microtubule-associated serine/threonine-protein kinase 3,MAST3_XENLA,Microtubule-associated serine/threonine-protein kinase 3,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,KEGG:xla:447257`KO:K08789,.,PF00595.24^PDZ^PDZ domain^295-356^E:1.9e-08,PF13180.6^PDZ_2^PDZ domain^306-340^E:3.2e-06,PF17820.1^PDZ_6^PDZ domain^309-355^E:2.7e-11,NA,NA,,
no,MJ,ST3,DN7_c0_g1_i1,DN7_c0_g1,MAST3_XENLA,Microtubule-associated serine/threonine-protein kinase 3,.,NA,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:xla:447257`KO:K08789,.,.,NA,NA,NA,NA,,
no,MJ,ST3,DN98986_c0_g1_i2,DN98986_c0_g1,BEST3_HUMAN,Bestrophin-3,BEST3_HUMAN,Bestrophin-3,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,KEGG:hsa:144453`KO:K13880,ENOG410XS3J^bestrophin,"PF01062.21^Bestrophin^Bestrophin, RFP-TM, chloride channel^25-117^E:2.7e-27",NA,NA,NA,NA,,
no,MJ,ST3,DN98986_c0_g1_i1,DN98986_c0_g1,BEST3_HUMAN,Bestrophin-3,BEST3_HUMAN,Bestrophin-3,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,KEGG:hsa:144453`KO:K13880,ENOG410XS3J^bestrophin,"PF01062.21^Bestrophin^Bestrophin, RFP-TM, chloride channel^8-124^E:6.7e-35",NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i9,DN14297_c0_g1,ST3A1_MOUSE,Amine sulfotransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0051923^biological_process^sulfation,NA,.,NA,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i1,DN14297_c0_g1,ST3A1_RABIT,Amine sulfotransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ocu:100009006`KO:K16949,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i8,DN14297_c0_g1,ST3A1_MOUSE,Amine sulfotransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0051923^biological_process^sulfation,NA,.,NA,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i5,DN14297_c0_g1,ST3A1_RABIT,Amine sulfotransferase,ST3A1_RABIT,Amine sulfotransferase,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,NA,NA,NA,KEGG:ocu:100009006`KO:K16949,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^11-185^E:3.8e-52,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i6,DN14297_c0_g1,ST3A1_RABIT,Amine sulfotransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,NA,NA,NA,.,NA,NA,NA,NA,KEGG:ocu:100009006`KO:K16949,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i4,DN14297_c0_g1,ST3A1_MOUSE,Amine sulfotransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0051923^biological_process^sulfation,NA,.,NA,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN14297_c0_g1_i2,DN14297_c0_g1,ST3A1_MOUSE,Amine sulfotransferase,ST3A1_MOUSE,Amine sulfotransferase,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0051923^biological_process^sulfation,NA,GO:0005737^cellular_component^cytoplasm,GO:0047685^molecular_function^amine sulfotransferase activity,GO:0008146^molecular_function^sulfotransferase activity,GO:0051923^biological_process^sulfation,NA,.,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^35-254^E:7.6e-65,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i4,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00069.25^Pkinase^Protein kinase domain^90-383^E:4e-62,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^93-243^E:1.5e-20,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^282-348^E:1.5e-06,PF00433.24^Pkinase_C^Protein kinase C terminal domain^402-443^E:1.2e-07,NA,,
no,MJ,ST3,DN4058_c0_g1_i13,DN4058_c0_g1,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i15,DN4058_c0_g1,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00433.24^Pkinase_C^Protein kinase C terminal domain^91-114^E:0.00016,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i3,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00069.25^Pkinase^Protein kinase domain^28-182^E:1.2e-42,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^31-181^E:1.6e-21,PF12330.8^Haspin_kinase^Haspin like kinase domain^88-190^E:6.7e-06,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i14,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00069.25^Pkinase^Protein kinase domain^28-297^E:7.9e-60,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^31-181^E:5.4e-21,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^220-284^E:1e-06,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i7,DN4058_c0_g1,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i2,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00069.25^Pkinase^Protein kinase domain^90-383^E:3.6e-62,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^93-243^E:1.4e-20,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^282-348^E:1.4e-06,PF00433.24^Pkinase_C^Protein kinase C terminal domain^402-425^E:0.00082,NA,,
no,MJ,ST3,DN4058_c0_g1_i8,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,PF00069.25^Pkinase^Protein kinase domain^28-162^E:1e-34,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^31-162^E:1.5e-14,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g1_i6,DN4058_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g2_i1,DN4058_c0_g2,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN4058_c0_g2_i2,DN4058_c0_g2,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN621_c1_g1_i2,DN621_c1_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,ST32C_HUMAN,Serine/threonine-protein kinase 32C,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^91-231^E:1.5e-36,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-233^E:5.6e-22,NA,NA,NA,,
no,MJ,ST3,DN621_c1_g1_i1,DN621_c1_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,ST32C_HUMAN,Serine/threonine-protein kinase 32C,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^91-231^E:1.6e-36,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-233^E:4.9e-22,NA,NA,NA,,
no,MJ,ST3,DN621_c1_g2_i6,DN621_c1_g2,ST32C_HUMAN,Serine/threonine-protein kinase 32C,ST32C_HUMAN,Serine/threonine-protein kinase 32C,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^91-342^E:3.4e-63,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^92-340^E:4.3e-35,PF14531.6^Kinase-like^Kinase-like^179-338^E:6.4e-10,NA,NA,,
no,MJ,ST3,DN621_c1_g2_i5,DN621_c1_g2,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN56559_c0_g1_i1,DN56559_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN38503_c0_g1_i2,DN38503_c0_g1,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,KEGG:hsa:9348`KO:K02578,ENOG410XQN4^N-deacetylase N-sulfotransferase (Heparan glucosaminyl),PF00685.27^Sulfotransfer_1^Sulfotransferase domain^12-176^E:6.3e-27,NA,NA,NA,NA,,
no,MJ,ST3,DN23631_c0_g1_i2,DN23631_c0_g1,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,KEGG:hsa:9348`KO:K02578,ENOG410XQN4^N-deacetylase N-sulfotransferase (Heparan glucosaminyl),PF12062.8^HSNSD^heparan sulfate-N-deacetylase^1-103^E:1.1e-58,NA,NA,NA,NA,,
no,MJ,ST3,DN23631_c0_g1_i1,DN23631_c0_g1,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,KEGG:hsa:9348`KO:K02578,ENOG410XQN4^N-deacetylase N-sulfotransferase (Heparan glucosaminyl),PF12062.8^HSNSD^heparan sulfate-N-deacetylase^1-138^E:2.7e-86,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^228-338^E:2.4e-20,NA,NA,NA,,
no,MJ,ST3,DN23631_c0_g1_i3,DN23631_c0_g1,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,KEGG:hsa:9348`KO:K02578,ENOG410XQN4^N-deacetylase N-sulfotransferase (Heparan glucosaminyl),PF12062.8^HSNSD^heparan sulfate-N-deacetylase^1-138^E:9.7e-87,NA,NA,NA,NA,,
no,MJ,ST3,DN33005_c0_g1_i1,DN33005_c0_g1,MGST3_HUMAN,Microsomal glutathione S-transferase 3 {ECO:0000305},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,.,NA,NA,NA,NA,KEGG:hsa:4259`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN33065_c0_g1_i2,DN33065_c0_g1,H6ST3_MOUSE,Heparan-sulfate 6-O-sulfotransferase 3,H6ST3_MOUSE,Heparan-sulfate 6-O-sulfotransferase 3,GO:0016021^cellular_component^integral component of membrane,GO:0017095^molecular_function^heparan sulfate 6-O-sulfotransferase activity,"GO:0015015^biological_process^heparan sulfate proteoglycan biosynthetic process, enzymatic modification",NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0017095^molecular_function^heparan sulfate 6-O-sulfotransferase activity,"GO:0015015^biological_process^heparan sulfate proteoglycan biosynthetic process, enzymatic modification",NA,NA,KEGG:mmu:50787`KO:K08103,ENOG410XSW4^Heparan sulfate 6-o-sulfotransferase,PF03567.14^Sulfotransfer_2^Sulfotransferase family^1-169^E:3.6e-48,NA,NA,NA,NA,,
no,MJ,ST3,DN19944_c0_g1_i6,DN19944_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,ST32A_MOUSE,Serine/threonine-protein kinase 32A,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF14531.6^Kinase-like^Kinase-like^8-134^E:1.2e-09,PF00069.25^Pkinase^Protein kinase domain^9-146^E:9.2e-31,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^11-136^E:3.4e-16,NA,NA,,
no,MJ,ST3,DN19944_c0_g1_i2,DN19944_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,ST32A_MOUSE,Serine/threonine-protein kinase 32A,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^23-280^E:1.4e-64,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^24-270^E:3.4e-40,PF14531.6^Kinase-like^Kinase-like^127-268^E:8.4e-14,NA,NA,,
no,MJ,ST3,DN19944_c0_g1_i4,DN19944_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,ST32A_MOUSE,Serine/threonine-protein kinase 32A,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF14531.6^Kinase-like^Kinase-like^8-134^E:1.7e-09,PF00069.25^Pkinase^Protein kinase domain^9-146^E:1.3e-30,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^11-136^E:4.8e-16,NA,NA,,
no,MJ,ST3,DN19944_c0_g1_i1,DN19944_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,ST32A_MOUSE,Serine/threonine-protein kinase 32A,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^4-111^E:3.2e-17,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^16-101^E:4.7e-09,NA,NA,NA,,
no,MJ,ST3,DN19944_c0_g2_i2,DN19944_c0_g2,ST32A_MOUSE,Serine/threonine-protein kinase 32A,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,.,NA,NA,NA,NA,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN19944_c0_g2_i1,DN19944_c0_g2,ST32A_MOUSE,Serine/threonine-protein kinase 32A,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,.,NA,NA,NA,NA,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN19944_c0_g3_i1,DN19944_c0_g3,ST32B_MOUSE,Serine/threonine-protein kinase 32B,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:mmu:64293`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN19944_c0_g3_i2,DN19944_c0_g3,ST32B_MOUSE,Serine/threonine-protein kinase 32B,ST32B_HUMAN,Serine/threonine-protein kinase 32B,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,KEGG:hsa:55351`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,PF00069.25^Pkinase^Protein kinase domain^27-287^E:4e-63,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^28-275^E:3.1e-35,PF14531.6^Kinase-like^Kinase-like^116-224^E:3.2e-10,NA,NA,,
no,MJ,ST3,DN16456_c1_g1_i1,DN16456_c1_g1,H6ST3_HUMAN,Heparan-sulfate 6-O-sulfotransferase 3,H6ST3_MOUSE,Heparan-sulfate 6-O-sulfotransferase 3,GO:0016021^cellular_component^integral component of membrane,GO:0017095^molecular_function^heparan sulfate 6-O-sulfotransferase activity,"GO:0015015^biological_process^heparan sulfate proteoglycan biosynthetic process, enzymatic modification",NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0017095^molecular_function^heparan sulfate 6-O-sulfotransferase activity,"GO:0015015^biological_process^heparan sulfate proteoglycan biosynthetic process, enzymatic modification",NA,NA,KEGG:mmu:50787`KO:K08103,ENOG410XSW4^Heparan sulfate 6-o-sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g1_i2,DN6141_c0_g1,MGST3_BOVIN,Microsomal glutathione S-transferase 3 {ECO:0000250|UniProtKB:O14880},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005635^cellular_component^nuclear envelope,GO:0004602^molecular_function^glutathione peroxidase activity,.,NA,NA,NA,NA,KEGG:bta:507346`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g1_i4,DN6141_c0_g1,MGST3_BOVIN,Microsomal glutathione S-transferase 3 {ECO:0000250|UniProtKB:O14880},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005635^cellular_component^nuclear envelope,GO:0004602^molecular_function^glutathione peroxidase activity,.,NA,NA,NA,NA,KEGG:bta:507346`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g1_i3,DN6141_c0_g1,MGST3_BOVIN,Microsomal glutathione S-transferase 3 {ECO:0000250|UniProtKB:O14880},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005635^cellular_component^nuclear envelope,GO:0004602^molecular_function^glutathione peroxidase activity,.,NA,NA,NA,NA,KEGG:bta:507346`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g2_i4,DN6141_c0_g2,MGST3_BOVIN,Microsomal glutathione S-transferase 3 {ECO:0000250|UniProtKB:O14880},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005635^cellular_component^nuclear envelope,GO:0004602^molecular_function^glutathione peroxidase activity,.,NA,NA,NA,NA,KEGG:bta:507346`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g2_i1,DN6141_c0_g2,MGST3_HUMAN,Microsomal glutathione S-transferase 3 {ECO:0000305},MGST3_HUMAN,Microsomal glutathione S-transferase 3 {ECO:0000305},GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,KEGG:hsa:4259`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,PF01124.18^MAPEG^MAPEG family^65-179^E:4.4e-22,NA,NA,NA,NA,,
no,MJ,ST3,DN6141_c0_g4_i1,DN6141_c0_g4,MGST3_BOVIN,Microsomal glutathione S-transferase 3 {ECO:0000250|UniProtKB:O14880},.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005635^cellular_component^nuclear envelope,GO:0004602^molecular_function^glutathione peroxidase activity,.,NA,NA,NA,NA,KEGG:bta:507346`KO:K00799,ENOG4111URX^microsomal glutathione S-transferase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN30268_c0_g1_i2,DN30268_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,.,NA,NA,NA,NA,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN30268_c0_g1_i1,DN30268_c0_g1,ST32A_MOUSE,Serine/threonine-protein kinase 32A,.,NA,GO:0005886^cellular_component^plasma membrane,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,.,NA,NA,NA,NA,KEGG:mmu:269019`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN11340_c0_g1_i8,DN11340_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN11340_c0_g1_i5,DN11340_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN11340_c0_g1_i4,DN11340_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN11340_c0_g1_i9,DN11340_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN30885_c0_g1_i1,DN30885_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN30885_c0_g1_i2,DN30885_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN142003_c0_g1_i1,DN142003_c0_g1,ST32B_MOUSE,Serine/threonine-protein kinase 32B,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:mmu:64293`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN110947_c0_g1_i2,DN110947_c0_g1,ST32C_HUMAN,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:hsa:282974`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN100131_c0_g1_i1,DN100131_c0_g1,MAST3_HUMAN,Microtubule-associated serine/threonine-protein kinase 3,.,NA,GO:0005524^molecular_function^ATP binding,GO:0000287^molecular_function^magnesium ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0007010^biological_process^cytoskeleton organization,GO:0035556^biological_process^intracellular signal transduction,.,NA,NA,NA,NA,KEGG:hsa:23031`KO:K08789,ENOG410XPWX^microtubule associated serine threonine kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN276099_c0_g1_i1,DN276099_c0_g1,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,NDST3_HUMAN,Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,GO:0005794^cellular_component^Golgi apparatus,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0015016^molecular_function^[heparan sulfate]-glucosamine N-sulfotransferase activity,GO:0019213^molecular_function^deacetylase activity,KEGG:hsa:9348`KO:K02578,ENOG410XQN4^N-deacetylase N-sulfotransferase (Heparan glucosaminyl),PF12062.8^HSNSD^heparan sulfate-N-deacetylase^1-101^E:4.9e-23,NA,NA,NA,NA,,
no,MJ,ST3,DN203668_c0_g1_i1,DN203668_c0_g1,ST38L_HUMAN,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:hsa:23012`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN247387_c0_g1_i1,DN247387_c0_g1,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN323733_c0_g1_i1,DN323733_c0_g1,ST38L_MOUSE,Serine/threonine-protein kinase 38-like,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0016020^cellular_component^membrane,GO:0003779^molecular_function^actin binding,.,NA,NA,NA,NA,KEGG:mmu:232533`KO:K08790,ENOG410XQC0^serine threonine-protein kinase,.,NA,NA,NA,NA,,
no,MJ,ST3,DN398530_c0_g1_i1,DN398530_c0_g1,BEST3_HUMAN,Bestrophin-3,BEST3_HUMAN,Bestrophin-3,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0043271^biological_process^negative regulation of ion transport,NA,KEGG:hsa:144453`KO:K13880,ENOG410XS3J^bestrophin,"PF01062.21^Bestrophin^Bestrophin, RFP-TM, chloride channel^1-84^E:2.8e-37",NA,NA,NA,NA,,
no,MJ,ST3,DN442781_c0_g1_i1,DN442781_c0_g1,ST32C_MOUSE,Serine/threonine-protein kinase 32C,.,NA,GO:0005524^molecular_function^ATP binding,GO:0046872^molecular_function^metal ion binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,GO:0035556^biological_process^intracellular signal transduction,GO:0018105^biological_process^peptidyl-serine phosphorylation,.,NA,NA,NA,NA,KEGG:mmu:57740`KO:K08793,ENOG410XNPH^protein serine/threonine kinase activity,.,NA,NA,NA,NA,,
no,MJ,ST3,DN441417_c0_g1_i1,DN441417_c0_g1,BEST3_MOUSE,Bestrophin-3,BEST3_MOUSE,Bestrophin-3,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0015698^biological_process^inorganic anion transport,GO:0043271^biological_process^negative regulation of ion transport,GO:0034707^cellular_component^chloride channel complex,GO:0005886^cellular_component^plasma membrane,GO:0005254^molecular_function^chloride channel activity,GO:0015698^biological_process^inorganic anion transport,GO:0043271^biological_process^negative regulation of ion transport,KEGG:mmu:382427`KO:K13880,ENOG410XS3J^bestrophin,.,NA,NA,NA,NA,,
no,MJ,ST6,DN18563_c0_g1_i4,DN18563_c0_g1,ST6B1_MOUSE,Sulfotransferase 6B1,ST6B1_MOUSE,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,KEGG:mmu:73671`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^16-247^E:4.5e-58,NA,NA,NA,NA,,
no,MJ,ST6,DN18563_c0_g1_i1,DN18563_c0_g1,ST6B1_MOUSE,Sulfotransferase 6B1,ST6B1_MOUSE,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,KEGG:mmu:73671`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^16-247^E:6e-58,NA,NA,NA,NA,,
no,MJ,ST6,DN18563_c0_g1_i2,DN18563_c0_g1,ST6B1_MOUSE,Sulfotransferase 6B1,ST6B1_MOUSE,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,KEGG:mmu:73671`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^9-250^E:1.2e-64,NA,NA,NA,NA,,
no,MJ,ST6,DN3291_c0_g1_i2,DN3291_c0_g1,ST65G_HUMAN,STAGA complex 65 subunit gamma,ST65G_MOUSE,STAGA complex 65 subunit gamma,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,KEGG:mmu:72195`KO:K11316,ENOG410YK24^Suppressor of Ty 7 (S. cerevisiae)-like,PF07524.13^Bromo_TP^Bromodomain associated^149-227^E:1.4e-21,NA,NA,NA,NA,,
no,MJ,ST6,DN3291_c0_g1_i3,DN3291_c0_g1,ST65G_HUMAN,STAGA complex 65 subunit gamma,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,.,NA,NA,NA,NA,KEGG:hsa:9913`KO:K11316,ENOG410YK24^Suppressor of Ty 7 (S. cerevisiae)-like,.,NA,NA,NA,NA,,
no,MJ,ST6,DN3291_c0_g1_i1,DN3291_c0_g1,ST65G_HUMAN,STAGA complex 65 subunit gamma,ST65G_MOUSE,STAGA complex 65 subunit gamma,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,KEGG:mmu:72195`KO:K11316,ENOG410YK24^Suppressor of Ty 7 (S. cerevisiae)-like,PF07524.13^Bromo_TP^Bromodomain associated^149-227^E:1.4e-21,NA,NA,NA,NA,,
no,MJ,ST6,DN985_c0_g2_i4,DN985_c0_g2,ST6B1_MOUSE,Sulfotransferase 6B1,ST6B1_MOUSE,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,KEGG:mmu:73671`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^57-300^E:5.7e-58,PF13469.6^Sulfotransfer_3^Sulfotransferase family^144-238^E:2e-06,NA,NA,NA,,
no,MJ,ST6,DN985_c0_g2_i2,DN985_c0_g2,ST6B1_MOUSE,Sulfotransferase 6B1,ST6B1_PANTR,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,KEGG:mmu:73671`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^57-107^E:3.2e-06,NA,NA,NA,NA,,
no,MJ,ST6,DN985_c0_g2_i5,DN985_c0_g2,ST6B1_PANTR,Sulfotransferase 6B1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,.,NA,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,.,NA,NA,NA,NA,,
no,MJ,ST6,DN985_c0_g2_i3,DN985_c0_g2,ST6B1_PANTR,Sulfotransferase 6B1,ST6B1_HUMAN,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005829^cellular_component^cytosol,GO:0008146^molecular_function^sulfotransferase activity,GO:0050427^biological_process^3'-phosphoadenosine 5'-phosphosulfate metabolic process,NA,NA,KEGG:hsa:391365`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^1-90^E:2.5e-16,NA,NA,NA,NA,,
no,MJ,ST6,DN229761_c0_g1_i1,DN229761_c0_g1,ST6B1_PANTR,Sulfotransferase 6B1,ST6B1_PANTR,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^74-122^E:5.2e-13,NA,NA,NA,NA,,
no,MJ,ST6,DN229761_c0_g1_i3,DN229761_c0_g1,ST6B1_PANTR,Sulfotransferase 6B1,ST6B1_PANTR,Sulfotransferase 6B1,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0008146^molecular_function^sulfotransferase activity,NA,NA,NA,.,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^74-122^E:5.2e-13,NA,NA,NA,NA,,
no,MJ,ST6,DN379320_c0_g1_i1,DN379320_c0_g1,ST65G_MOUSE,STAGA complex 65 subunit gamma,.,NA,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0030914^cellular_component^STAGA complex,GO:0004402^molecular_function^histone acetyltransferase activity,GO:0046982^molecular_function^protein heterodimerization activity,.,NA,NA,NA,NA,KEGG:mmu:72195`KO:K11316,ENOG410YK24^Suppressor of Ty 7 (S. cerevisiae)-like,.,NA,NA,NA,NA,,
no,MJ,ST6,DN348693_c0_g1_i1,DN348693_c0_g1,ST6B1_DANRE,Sulfotransferase 6B1 {ECO:0000305},ST6B1_DANRE,Sulfotransferase 6B1 {ECO:0000305},GO:0008146^molecular_function^sulfotransferase activity,GO:0071466^biological_process^cellular response to xenobiotic stimulus,NA,NA,NA,GO:0008146^molecular_function^sulfotransferase activity,GO:0071466^biological_process^cellular response to xenobiotic stimulus,NA,NA,NA,KEGG:dre:322462`KO:K22523,ENOG4111H56^Sulfotransferase,PF00685.27^Sulfotransfer_1^Sulfotransferase domain^1-157^E:1e-44,NA,NA,NA,NA,,
yes,AD,STAT1,DN15046_c0_g1_i11,DN15046_c0_g1,STAT1_HUMAN,Signal transducer and activator of transcription 1-alpha/beta,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:6772`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN23650_c0_g1_i3,DN23650_c0_g1,STAT1_MOUSE,Signal transducer and activator of transcription 1,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,.,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN23650_c0_g1_i4,DN23650_c0_g1,STAT1_MOUSE,Signal transducer and activator of transcription 1,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,.,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN18052_c0_g1_i2,DN18052_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN2413_c0_g1_i2,DN2413_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,STAT1_PIG,Signal transducer and activator of transcription 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,"PF02864.15^STAT_bind^STAT protein, DNA binding domain^4-92^E:1.4e-24",PF00017.24^SH2^SH2 domain^214-272^E:4.3e-10,PF12162.8^STAT1_TAZ2bind^STAT1 TAZ2 binding domain^349-373^E:6.3e-15,NA,NA,,
yes,AD,STAT1,DN2413_c0_g1_i3,DN2413_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,STAT1_PIG,Signal transducer and activator of transcription 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^55-172^E:3.2e-41","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^194-363^E:2e-56","PF02864.15^STAT_bind^STAT protein, DNA binding domain^378-423^E:3.1e-08",NA,NA,,
yes,AD,STAT1,DN2413_c0_g1_i5,DN2413_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,STAT1_PIG,Signal transducer and activator of transcription 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,"PF02864.15^STAT_bind^STAT protein, DNA binding domain^4-92^E:1.4e-24",PF00017.24^SH2^SH2 domain^214-272^E:4.4e-10,PF12162.8^STAT1_TAZ2bind^STAT1 TAZ2 binding domain^349-373^E:6.4e-15,NA,NA,,
yes,AD,STAT1,DN2413_c0_g1_i6,DN2413_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,STAT1_PIG,Signal transducer and activator of transcription 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,"PF02864.15^STAT_bind^STAT protein, DNA binding domain^4-92^E:1.3e-24",PF00017.24^SH2^SH2 domain^214-272^E:4.1e-10,PF12162.8^STAT1_TAZ2bind^STAT1 TAZ2 binding domain^349-371^E:1.2e-12,NA,NA,,
yes,AD,STAT1,DN2413_c0_g1_i8,DN2413_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,STAT1_PIG,Signal transducer and activator of transcription 1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^55-172^E:8.4e-41","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^194-363^E:6.1e-56","PF02864.15^STAT_bind^STAT protein, DNA binding domain^378-513^E:3.9e-40",PF00017.24^SH2^SH2 domain^635-692^E:1.2e-09,PF12162.8^STAT1_TAZ2bind^STAT1 TAZ2 binding domain^770-794^E:1.5e-14,,
yes,AD,STAT1,DN51353_c0_g2_i1,DN51353_c0_g2,STAT1_PIG,Signal transducer and activator of transcription 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN51353_c0_g2_i5,DN51353_c0_g2,STAT1_PIG,Signal transducer and activator of transcription 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN51353_c2_g1_i2,DN51353_c2_g1,STAT1_HUMAN,Signal transducer and activator of transcription 1-alpha/beta,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:6772`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN42376_c0_g1_i2,DN42376_c0_g1,STAT1_MOUSE,Signal transducer and activator of transcription 1,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,.,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN194798_c0_g1_i1,DN194798_c0_g1,STAT1_HUMAN,Signal transducer and activator of transcription 1-alpha/beta,.,NA,GO:0030424^cellular_component^axon,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0030425^cellular_component^dendrite,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:6772`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN114396_c0_g1_i1,DN114396_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT1,DN200365_c0_g1_i1,DN200365_c0_g1,STAT1_PIG,Signal transducer and activator of transcription 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005730^cellular_component^nucleolus,GO:0005634^cellular_component^nucleus,"GO:0001228^molecular_function^DNA-binding transcription activator activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:ssc:396655`KO:K11220,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN42282_c0_g1_i1,DN42282_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN75497_c0_g1_i1,DN75497_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN75497_c0_g1_i2,DN75497_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i3,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i14,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STA31_XENLA,Signal transducer and activator of transcription 3.1,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005886^cellular_component^plasma membrane,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:xla:779100`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,PF00017.24^SH2^SH2 domain^151-194^E:1.5e-10,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i7,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i1,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^43-160^E:2.9e-38","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^182-353^E:1.8e-53","PF02864.15^STAT_bind^STAT protein, DNA binding domain^367-505^E:5.9e-38",NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i8,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i2,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i15,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^43-160^E:4.4e-38","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^182-353^E:2.9e-53","PF02864.15^STAT_bind^STAT protein, DNA binding domain^367-505^E:9.4e-38",PF00017.24^SH2^SH2 domain^625-715^E:2.7e-13,NA,,
yes,AD,STAT3,DN2688_c0_g1_i13,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^43-160^E:1.4e-38","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^182-353^E:8e-54","PF02864.15^STAT_bind^STAT protein, DNA binding domain^367-411^E:2.1e-07",NA,NA,,
yes,AD,STAT3,DN2688_c0_g1_i5,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^43-160^E:3.9e-38","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^182-353^E:2.6e-53","PF02864.15^STAT_bind^STAT protein, DNA binding domain^367-505^E:8.3e-38",PF00017.24^SH2^SH2 domain^625-715^E:2.4e-13,NA,,
yes,AD,STAT3,DN2688_c0_g1_i4,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,"PF02865.17^STAT_int^STAT protein, protein interaction domain^43-160^E:5.5e-38","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^182-229^E:3.6e-08","PF01017.20^STAT_alpha^STAT protein, all-alpha domain^361-487^E:1.3e-42","PF02864.15^STAT_bind^STAT protein, DNA binding domain^501-639^E:1.2e-37",PF00017.24^SH2^SH2 domain^759-849^E:3.3e-13,,
yes,AD,STAT3,DN2688_c0_g1_i11,DN2688_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN44376_c0_g1_i3,DN44376_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN64245_c0_g1_i2,DN64245_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN132834_c0_g1_i1,DN132834_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
yes,AD,STAT3,DN115923_c0_g1_i2,DN115923_c0_g1,STAT3_CHICK,Signal transducer and activator of transcription 3,STAT3_CHICK,Signal transducer and activator of transcription 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:gga:420027`KO:K04692,ENOG410XPN8^signal transducer and activator of transcription,.,NA,NA,NA,NA,,
no,AD,TAP,DN79361_c0_g1_i2,DN79361_c0_g1,SMAD3_RAT,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:rno:25631`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN79361_c0_g1_i1,DN79361_c0_g1,SMAD3_RAT,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:rno:25631`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN19726_c0_g1_i1,DN19726_c0_g1,SMAD6_HUMAN,Mothers against decapentaplegic homolog 6,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005794^cellular_component^Golgi apparatus,GO:0016604^cellular_component^nuclear body,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4091`KO:K04677,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN11662_c0_g1_i6,DN11662_c0_g1,.,NA,LSTP_STASI,Lysostaphin,.,NA,NA,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0046872^molecular_function^metal ion binding,GO:0008237^molecular_function^metallopeptidase activity,GO:0071555^biological_process^cell wall organization,NA,KEGG:ag:AAA26655`KEGG:ag:AAB53783`KO:K08259,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN26076_c0_g1_i3,DN26076_c0_g1,SMAD6_CHICK,Mothers against decapentaplegic homolog 6,.,NA,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003682^molecular_function^chromatin binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN26076_c0_g1_i11,DN26076_c0_g1,SMAD6_CHICK,Mothers against decapentaplegic homolog 6,.,NA,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003682^molecular_function^chromatin binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i11,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i10,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,TAP2_HUMAN,Antigen peptide transporter 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,PF00664.23^ABC_membrane^ABC transporter transmembrane region^10-103^E:7.7e-11,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i4,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,TAP2_HUMAN,Antigen peptide transporter 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,PF00664.23^ABC_membrane^ABC transporter transmembrane region^10-113^E:5.4e-13,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i3,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i5,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i7,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN52432_c0_g1_i8,DN52432_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,TAP,DN8782_c0_g2_i9,DN8782_c0_g2,SMAD4_MOUSE,Mothers against decapentaplegic homolog 4,SMAD4_PIG,Mothers against decapentaplegic homolog 4,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:ssc:397142`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^37-90^E:3e-14,NA,NA,NA,NA,,
no,AD,TAP,DN8782_c0_g2_i10,DN8782_c0_g2,SMAD4_MOUSE,Mothers against decapentaplegic homolog 4,SMAD4_PIG,Mothers against decapentaplegic homolog 4,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:ssc:397142`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^37-90^E:3e-14,NA,NA,NA,NA,,
no,AD,TAP,DN8782_c0_g2_i1,DN8782_c0_g2,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,SMAD4_PIG,Mothers against decapentaplegic homolog 4,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:ssc:397142`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^37-90^E:3e-14,NA,NA,NA,NA,,
no,AD,TAP,DN8782_c0_g2_i2,DN8782_c0_g2,SMAD4_RAT,Mothers against decapentaplegic homolog 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0032991^cellular_component^protein-containing complex,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,.,NA,NA,NA,NA,KEGG:rno:50554`KO:K04501,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN8782_c0_g2_i6,DN8782_c0_g2,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,SMAD4_PIG,Mothers against decapentaplegic homolog 4,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:ssc:397142`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^37-90^E:3e-14,NA,NA,NA,NA,,
no,AD,TAP,DN1102_c1_g2_i1,DN1102_c1_g2,SMAD6_CHICK,Mothers against decapentaplegic homolog 6,SMAD6_CHICK,Mothers against decapentaplegic homolog 6,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003682^molecular_function^chromatin binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003682^molecular_function^chromatin binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,.,PF03165.16^MH1^MH1 domain^57-153^E:3.5e-28,PF03166.14^MH2^MH2 domain^213-376^E:1.1e-55,NA,NA,NA,,
no,AD,TAP,DN17171_c0_g1_i4,DN17171_c0_g1,MTAP2_HUMAN,Microtubule-associated protein 2,MTAP2_HUMAN,Microtubule-associated protein 2,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0097442^cellular_component^CA3 pyramidal cell dendrite,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0097442^cellular_component^CA3 pyramidal cell dendrite,KEGG:hsa:4133`KO:K10430,ENOG4111J07^Microtubule-associated protein,PF10522.9^RII_binding_1^RII binding domain^85-103^E:0.001,"PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^307-337^E:2.1e-11","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^338-367^E:9.1e-16","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^369-400^E:3.3e-15",NA,,
no,AD,TAP,DN17171_c0_g1_i3,DN17171_c0_g1,MTAP2_RAT,Microtubule-associated protein 2,MTAP2_RAT,Microtubule-associated protein 2,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,.,ENOG4111J07^Microtubule-associated protein,PF08377.10^MAP2_projctn^MAP2/Tau projection domain^287-1449^E:0,"PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^1608-1638^E:1e-10","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^1639-1669^E:1.1e-13","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^1670-1699^E:4.2e-15","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^1701-1732^E:1.5e-14",,
no,AD,TAP,DN17171_c0_g1_i5,DN17171_c0_g1,MTAP2_RAT,Microtubule-associated protein 2,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,.,NA,NA,NA,NA,.,ENOG4111J07^Microtubule-associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN17171_c0_g1_i6,DN17171_c0_g1,MTAP2_HUMAN,Microtubule-associated protein 2,MTAP2_HUMAN,Microtubule-associated protein 2,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0097442^cellular_component^CA3 pyramidal cell dendrite,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0097442^cellular_component^CA3 pyramidal cell dendrite,KEGG:hsa:4133`KO:K10430,ENOG4111J07^Microtubule-associated protein,PF08377.10^MAP2_projctn^MAP2/Tau projection domain^210-1332^E:0,NA,NA,NA,NA,,
no,AD,TAP,DN17171_c0_g1_i8,DN17171_c0_g1,MTAP2_RAT,Microtubule-associated protein 2,MTAP2_RAT,Microtubule-associated protein 2,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,.,ENOG4111J07^Microtubule-associated protein,PF10522.9^RII_binding_1^RII binding domain^85-103^E:0.0011,"PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^308-338^E:2.3e-11","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^339-369^E:2.6e-14","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^370-399^E:9.9e-16","PF00418.19^Tubulin-binding^Tau and MAP protein, tubulin-binding repeat^401-432^E:3.6e-15",,
no,AD,TAP,DN17171_c0_g1_i2,DN17171_c0_g1,MTAP2_HUMAN,Microtubule-associated protein 2,.,NA,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,GO:0097442^cellular_component^CA3 pyramidal cell dendrite,.,NA,NA,NA,NA,KEGG:hsa:4133`KO:K10430,ENOG4111J07^Microtubule-associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN17171_c0_g3_i1,DN17171_c0_g3,MTAP2_RAT,Microtubule-associated protein 2,.,NA,GO:0015629^cellular_component^actin cytoskeleton,GO:0150014^cellular_component^apical distal dendrite,GO:0043203^cellular_component^axon hillock,GO:0043194^cellular_component^axon initial segment,GO:0097441^cellular_component^basal dendrite,.,NA,NA,NA,NA,.,ENOG4111J07^Microtubule-associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN25312_c0_g1_i17,DN25312_c0_g1,.,NA,SMAD3_RAT,Mothers against decapentaplegic homolog 3,.,NA,NA,NA,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,KEGG:rno:25631`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN49992_c0_g1_i4,DN49992_c0_g1,COQ8A_HUMAN,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",.,NA,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:56997`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN24545_c4_g1_i1,DN24545_c4_g1,SNPH_HUMAN,Syntaphilin,SNPH_HUMAN,Syntaphilin,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,KEGG:hsa:9751,ENOG410XQEB^syntabulin (syntaxin-interacting),PF15290.6^Syntaphilin^Golgi-localised syntaxin-1-binding clamp^98-302^E:4.8e-125,NA,NA,NA,NA,,
no,AD,TAP,DN24545_c4_g1_i2,DN24545_c4_g1,SNPH_HUMAN,Syntaphilin,SNPH_MOUSE,Syntaphilin,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,KEGG:mmu:241727,ENOG410XQEB^syntabulin (syntaxin-interacting),PF15290.6^Syntaphilin^Golgi-localised syntaxin-1-binding clamp^1-113^E:1.9e-67,NA,NA,NA,NA,,
no,AD,TAP,DN24545_c4_g1_i3,DN24545_c4_g1,SNPH_HUMAN,Syntaphilin,SNPH_HUMAN,Syntaphilin,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,KEGG:hsa:9751,ENOG410XQEB^syntabulin (syntaxin-interacting),PF15290.6^Syntaphilin^Golgi-localised syntaxin-1-binding clamp^131-335^E:6.6e-125,NA,NA,NA,NA,,
no,AD,TAP,DN27571_c0_g1_i4,DN27571_c0_g1,JAZF1_PONAB,Juxtaposed with another zinc finger protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,GO:0006629^biological_process^lipid metabolic process,NA,.,NA,NA,NA,NA,KEGG:pon:100171957`KO:K19495,COG5189^JAZF zinc finger 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN27571_c0_g1_i5,DN27571_c0_g1,JAZF1_PONAB,Juxtaposed with another zinc finger protein 1,.,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,GO:0006629^biological_process^lipid metabolic process,NA,.,NA,NA,NA,NA,KEGG:pon:100171957`KO:K19495,COG5189^JAZF zinc finger 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN27571_c0_g1_i1,DN27571_c0_g1,JAZF1_PONAB,Juxtaposed with another zinc finger protein 1,JAZF1_PONAB,Juxtaposed with another zinc finger protein 1,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,GO:0006629^biological_process^lipid metabolic process,NA,GO:0005634^cellular_component^nucleus,GO:0046872^molecular_function^metal ion binding,GO:0003676^molecular_function^nucleic acid binding,GO:0006629^biological_process^lipid metabolic process,NA,KEGG:pon:100171957`KO:K19495,COG5189^JAZF zinc finger 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN86462_c0_g1_i5,DN86462_c0_g1,STAP1_HUMAN,Signal-transducing adaptor protein 1,STAP1_HUMAN,Signal-transducing adaptor protein 1,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:26228,ENOG4111PK4^signal transducing adaptor family member 1,PF00017.24^SH2^SH2 domain^212-287^E:5.3e-06,NA,NA,NA,NA,,
no,AD,TAP,DN86462_c0_g1_i1,DN86462_c0_g1,STAP1_HUMAN,Signal-transducing adaptor protein 1,STAP1_HUMAN,Signal-transducing adaptor protein 1,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:26228,ENOG4111PK4^signal transducing adaptor family member 1,PF00017.24^SH2^SH2 domain^50-125^E:1.5e-06,NA,NA,NA,NA,,
no,AD,TAP,DN86462_c0_g1_i7,DN86462_c0_g1,STAP1_HUMAN,Signal-transducing adaptor protein 1,STAP1_HUMAN,Signal-transducing adaptor protein 1,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:26228,ENOG4111PK4^signal transducing adaptor family member 1,PF00017.24^SH2^SH2 domain^236-311^E:6e-06,NA,NA,NA,NA,,
no,AD,TAP,DN86462_c0_g1_i6,DN86462_c0_g1,STAP1_HUMAN,Signal-transducing adaptor protein 1,STAP1_HUMAN,Signal-transducing adaptor protein 1,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0005739^cellular_component^mitochondrion,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:26228,ENOG4111PK4^signal transducing adaptor family member 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i15,DN4539_c0_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,PF00953.21^Glycos_transf_4^Glycosyl transferase family 4^1-26^E:0.00018,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i1,DN4539_c0_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i13,DN4539_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i19,DN4539_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i9,DN4539_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i11,DN4539_c0_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,PF00953.21^Glycos_transf_4^Glycosyl transferase family 4^1-26^E:0.00018,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i16,DN4539_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c0_g1_i4,DN4539_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN4539_c2_g1_i1,DN4539_c2_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN3626_c0_g1_i1,DN3626_c0_g1,SMAD9_HUMAN,Mothers against decapentaplegic homolog 9,SMAD9_HUMAN,Mothers against decapentaplegic homolog 9,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:4093`KO:K16791,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^35-135^E:3.5e-42,PF03166.14^MH2^MH2 domain^271-443^E:1.8e-74,NA,NA,NA,,
no,AD,TAP,DN3626_c0_g1_i2,DN3626_c0_g1,SMAD9_HUMAN,Mothers against decapentaplegic homolog 9,SMAD9_HUMAN,Mothers against decapentaplegic homolog 9,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,KEGG:hsa:4093`KO:K16791,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^35-135^E:3.6e-42,PF03166.14^MH2^MH2 domain^280-452^E:1.9e-74,NA,NA,NA,,
no,AD,TAP,DN60262_c0_g1_i1,DN60262_c0_g1,SMAD9_HUMAN,Mothers against decapentaplegic homolog 9,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005622^cellular_component^intracellular,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:hsa:4093`KO:K16791,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN2772_c0_g1_i1,DN2772_c0_g1,ADCK5_HUMAN,Uncharacterized aarF domain-containing protein kinase 5,ADCK5_MOUSE,Uncharacterized aarF domain-containing protein kinase 5,GO:0016021^cellular_component^integral component of membrane,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,KEGG:mmu:268822`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^198-313^E:5.1e-34,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i8,DN9493_c0_g1,KTAP2_HUMAN,Keratinocyte-associated protein 2,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0008250^cellular_component^oligosaccharyltransferase complex,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:200185,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i7,DN9493_c0_g1,KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:cfa:480131,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i3,DN9493_c0_g1,KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:cfa:480131,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i9,DN9493_c0_g1,KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:cfa:480131,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i6,DN9493_c0_g1,KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,KEGG:cfa:480131,ENOG4111ZNW^Keratinocyte associated protein 2,PF09775.9^Keratin_assoc^Keratinocyte-associated protein 2^16-108^E:1e-40,NA,NA,NA,NA,,
no,AD,TAP,DN9493_c0_g1_i4,DN9493_c0_g1,KTAP2_BOVIN,Keratinocyte-associated protein 2,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0008250^cellular_component^oligosaccharyltransferase complex,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:bta:540389,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN7633_c2_g1_i1,DN7633_c2_g1,SMAD1_COTJA,Mothers against decapentaplegic homolog 1,SMAD1_COTJA,Mothers against decapentaplegic homolog 1,GO:0005737^cellular_component^cytoplasm,GO:0005637^cellular_component^nuclear inner membrane,GO:0005667^cellular_component^transcription factor complex,GO:0070410^molecular_function^co-SMAD binding,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0005737^cellular_component^cytoplasm,GO:0005637^cellular_component^nuclear inner membrane,GO:0005667^cellular_component^transcription factor complex,GO:0070410^molecular_function^co-SMAD binding,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,KEGG:cjo:107313166`KO:K04676,.,PF03165.16^MH1^MH1 domain^31-131^E:5.6e-42,PF03166.14^MH2^MH2 domain^269-441^E:2.8e-75,NA,NA,NA,,
no,AD,TAP,DN48800_c1_g1_i1,DN48800_c1_g1,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN249_c0_g1_i1,DN249_c0_g1,SMAD2_HUMAN,Mothers against decapentaplegic homolog 2,SMAD2_HUMAN,Mothers against decapentaplegic homolog 2,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4087`KO:K04500,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^41-171^E:4.6e-43,PF03166.14^MH2^MH2 domain^273-443^E:1.7e-79,NA,NA,NA,,
no,AD,TAP,DN249_c0_g1_i3,DN249_c0_g1,SMAD2_HUMAN,Mothers against decapentaplegic homolog 2,SMAD2_HUMAN,Mothers against decapentaplegic homolog 2,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4087`KO:K04500,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^22-84^E:6.4e-30,PF03166.14^MH2^MH2 domain^186-356^E:1.1e-79,NA,NA,NA,,
no,AD,TAP,DN249_c0_g2_i1,DN249_c0_g2,SMAD2_RAT,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:rno:29357`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN3914_c0_g2_i4,DN3914_c0_g2,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,PF05346.11^DUF747^Eukaryotic membrane protein family^1-88^E:3e-13,NA,NA,NA,NA,,
no,AD,TAP,DN3914_c0_g2_i3,DN3914_c0_g2,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN3914_c0_g2_i7,DN3914_c0_g2,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN3914_c0_g2_i2,DN3914_c0_g2,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN3914_c0_g2_i5,DN3914_c0_g2,TAPT1_XENLA,Transmembrane anterior posterior transformation protein 1 homolog,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005737^cellular_component^cytoplasm,GO:0016021^cellular_component^integral component of membrane,GO:0051216^biological_process^cartilage development,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,PF05346.11^DUF747^Eukaryotic membrane protein family^180-231^E:2.6e-17,NA,NA,NA,NA,,
no,AD,TAP,DN3120_c0_g1_i3,DN3120_c0_g1,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,KEGG:gga:395679`KO:K16790,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^32-132^E:5.3e-42,PF03166.14^MH2^MH2 domain^269-419^E:1.1e-58,NA,NA,NA,,
no,AD,TAP,DN3120_c0_g1_i4,DN3120_c0_g1,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,KEGG:gga:395679`KO:K16790,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^32-132^E:5.8e-42,PF03166.14^MH2^MH2 domain^269-441^E:8.3e-76,PF10401.9^IRF-3^Interferon-regulatory factor 3^321-403^E:0.00025,NA,NA,,
no,AD,TAP,DN3120_c0_g1_i6,DN3120_c0_g1,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,KEGG:gga:395679`KO:K16790,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^32-132^E:5.8e-42,PF03166.14^MH2^MH2 domain^269-441^E:8.3e-76,PF10401.9^IRF-3^Interferon-regulatory factor 3^321-403^E:0.00025,NA,NA,,
no,AD,TAP,DN3120_c0_g1_i7,DN3120_c0_g1,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,SMAD5_CHICK,Mothers against decapentaplegic homolog 5,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,KEGG:gga:395679`KO:K16790,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^32-132^E:3.3e-42,PF03166.14^MH2^MH2 domain^269-339^E:6.4e-25,NA,NA,NA,,
no,AD,TAP,DN25591_c0_g2_i4,DN25591_c0_g2,KTAP2_CANLF,Keratinocyte-associated protein 2 {ECO:0000250|UniProtKB:Q8N6L1},.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042543^biological_process^protein N-linked glycosylation via arginine,NA,NA,.,NA,NA,NA,NA,KEGG:cfa:480131,ENOG4111ZNW^Keratinocyte associated protein 2,.,NA,NA,NA,NA,,
no,AD,TAP,DN84495_c0_g1_i5,DN84495_c0_g1,CFA69_PAPAN,Cilia- and flagella-associated protein 69 {ECO:0000250|UniProtKB:A5D8W1},CFA69_CALJA,Cilia- and flagella-associated protein 69 {ECO:0000250|UniProtKB:A5D8W1},GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,KEGG:cjc:100405268,ENOG410XTAP^chromosome 7 open reading frame 63,.,NA,NA,NA,NA,,
no,AD,TAP,DN84495_c0_g1_i4,DN84495_c0_g1,CFA69_HUMAN,Cilia- and flagella-associated protein 69 {ECO:0000312|HGNC:HGNC:26107},CFA69_HUMAN,Cilia- and flagella-associated protein 69 {ECO:0000312|HGNC:HGNC:26107},GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,KEGG:hsa:79846,ENOG410XTAP^chromosome 7 open reading frame 63,.,NA,NA,NA,NA,,
no,AD,TAP,DN84495_c0_g1_i3,DN84495_c0_g1,CFA69_MOUSE,Cilia- and flagella-associated protein 69 {ECO:0000312|MGI:MGI:2443778},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,.,NA,NA,NA,NA,KEGG:mmu:207686,ENOG410XTAP^chromosome 7 open reading frame 63,.,NA,NA,NA,NA,,
no,AD,TAP,DN5263_c0_g1_i1,DN5263_c0_g1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,KEGG:gga:419456`KO:K00810,"COG1575^1,4-dihydroxy-2-naphthoate octaprenyltransferase",PF01040.18^UbiA^UbiA prenyltransferase family^58-312^E:3.4e-41,NA,NA,NA,NA,,
no,AD,TAP,DN5263_c0_g1_i8,DN5263_c0_g1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,KEGG:gga:419456`KO:K00810,"COG1575^1,4-dihydroxy-2-naphthoate octaprenyltransferase",PF01040.18^UbiA^UbiA prenyltransferase family^10-264^E:2e-41,NA,NA,NA,NA,,
no,AD,TAP,DN5263_c0_g1_i4,DN5263_c0_g1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,KEGG:gga:419456`KO:K00810,"COG1575^1,4-dihydroxy-2-naphthoate octaprenyltransferase",PF01040.18^UbiA^UbiA prenyltransferase family^58-312^E:3.4e-41,NA,NA,NA,NA,,
no,AD,TAP,DN4313_c0_g1_i2,DN4313_c0_g1,STAP2_HUMAN,Signal-transducing adaptor protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,.,NA,NA,NA,NA,KEGG:hsa:55620,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN4313_c0_g1_i5,DN4313_c0_g1,STAP2_HUMAN,Signal-transducing adaptor protein 2,STAP2_HUMAN,Signal-transducing adaptor protein 2,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,KEGG:hsa:55620,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN4313_c0_g1_i4,DN4313_c0_g1,STAP2_HUMAN,Signal-transducing adaptor protein 2,STAP2_HUMAN,Signal-transducing adaptor protein 2,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,KEGG:hsa:55620,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN4313_c0_g1_i8,DN4313_c0_g1,STAP2_HUMAN,Signal-transducing adaptor protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,.,NA,NA,NA,NA,KEGG:hsa:55620,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN4313_c0_g1_i6,DN4313_c0_g1,STAP2_HUMAN,Signal-transducing adaptor protein 2,.,NA,GO:0005829^cellular_component^cytosol,GO:0005886^cellular_component^plasma membrane,GO:0035591^molecular_function^signaling adaptor activity,GO:0042531^biological_process^positive regulation of tyrosine phosphorylation of STAT protein,NA,.,NA,NA,NA,NA,KEGG:hsa:55620,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN36827_c0_g1_i1,DN36827_c0_g1,FL2D_DANRE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0016607^cellular_component^nuclear speck,GO:0005634^cellular_component^nucleus,GO:0036396^cellular_component^RNA N6-methyladenosine methyltransferase complex,GO:0007049^biological_process^cell cycle,.,NA,NA,NA,NA,KEGG:dre:334058`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN11518_c0_g1_i1,DN11518_c0_g1,ADCK1_CHICK,Uncharacterized aarF domain-containing protein kinase 1,.,NA,GO:0005576^cellular_component^extracellular region,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:gga:423382`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN11518_c0_g1_i3,DN11518_c0_g1,ADCK1_CHICK,Uncharacterized aarF domain-containing protein kinase 1,ADCK1_CHICK,Uncharacterized aarF domain-containing protein kinase 1,GO:0005576^cellular_component^extracellular region,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,GO:0005576^cellular_component^extracellular region,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,KEGG:gga:423382`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^90-204^E:1.5e-38,NA,NA,NA,NA,,
no,AD,TAP,DN10620_c0_g1_i4,DN10620_c0_g1,COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,KEGG:rno:360887`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^318-432^E:1.2e-33,NA,NA,NA,NA,,
no,AD,TAP,DN10620_c0_g1_i10,DN10620_c0_g1,COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",COQ8A_MOUSE,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,KEGG:mmu:67426`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN10620_c0_g1_i1,DN10620_c0_g1,COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",.,NA,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:rno:360887`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN10620_c0_g1_i8,DN10620_c0_g1,COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,KEGG:rno:360887`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^318-432^E:1.2e-33,NA,NA,NA,NA,,
no,AD,TAP,DN10620_c0_g1_i7,DN10620_c0_g1,COQ8A_RAT,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",COQ8A_DANRE,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,KEGG:dre:437001`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i6,DN1928_c7_g1,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,SMAD4_MOUSE,Mothers against decapentaplegic homolog 4,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,KEGG:mmu:17128`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^9-109^E:2.3e-39,NA,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i3,DN1928_c7_g1,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:bta:540248`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^39-139^E:4.5e-38,PF03166.14^MH2^MH2 domain^325-534^E:6e-77,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i8,DN1928_c7_g1,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,KEGG:bta:540248`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^9-109^E:4e-38,PF03166.14^MH2^MH2 domain^288-497^E:5.2e-77,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i2,DN1928_c7_g1,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:bta:540248`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i1,DN1928_c7_g1,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:bta:540248`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN1928_c7_g1_i4,DN1928_c7_g1,SMAD4_BOVIN,Mothers against decapentaplegic homolog 4,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4089`KO:K04501,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^9-109^E:1.1e-38,NA,NA,NA,NA,,
yes,AD,TAP,DN1977_c0_g1_i12,DN1977_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,TAP2_HUMAN,Antigen peptide transporter 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,PF00664.23^ABC_membrane^ABC transporter transmembrane region^152-414^E:7.4e-41,PF00005.27^ABC_tran^ABC transporter^483-632^E:2.4e-31,NA,NA,NA,,
yes,AD,TAP,DN1977_c0_g1_i9,DN1977_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,TAP2_MOUSE,Antigen peptide transporter 2,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,KEGG:mmu:21355`KO:K05654,COG1132^(ABC) transporter,PF00664.23^ABC_membrane^ABC transporter transmembrane region^152-245^E:3.3e-08,NA,NA,NA,NA,,
yes,AD,TAP,DN60592_c0_g1_i3,DN60592_c0_g1,TAP2_RAT,Antigen peptide transporter 2,TAP1_HUMAN,Antigen peptide transporter 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,GO:0042825^cellular_component^TAP complex,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,KEGG:hsa:6890`KO:K05653,COG1132^(ABC) transporter,PF00005.27^ABC_tran^ABC transporter^1-59^E:1.6e-11,NA,NA,NA,NA,,
yes,AD,TAP,DN60592_c0_g1_i1,DN60592_c0_g1,TAP2_MOUSE,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,.,NA,NA,NA,NA,KEGG:mmu:21355`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN60592_c0_g1_i2,DN60592_c0_g1,TAP2_RAT,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,GO:0042825^cellular_component^TAP complex,.,NA,NA,NA,NA,KEGG:rno:24812`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN34245_c0_g1_i5,DN34245_c0_g1,TAP2_RAT,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,GO:0042825^cellular_component^TAP complex,.,NA,NA,NA,NA,KEGG:rno:24812`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN34245_c0_g1_i4,DN34245_c0_g1,TAP2_HUMAN,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6891`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN34245_c0_g1_i3,DN34245_c0_g1,TAP2_RAT,Antigen peptide transporter 2,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0042824^cellular_component^MHC class I peptide loading complex,GO:0042825^cellular_component^TAP complex,.,NA,NA,NA,NA,KEGG:rno:24812`KO:K05654,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,TAP,DN49757_c0_g1_i1,DN49757_c0_g1,SMAD2_RAT,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:rno:29357`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN6835_c0_g1_i1,DN6835_c0_g1,TMP_BPLSK,Probable tape measure protein {ECO:0000250|UniProtKB:Q9MCC1},.,NA,GO:0019012^cellular_component^virion,GO:0098003^biological_process^viral tail assembly,NA,NA,NA,.,NA,NA,NA,NA,KEGG:vg:1261262,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN64361_c0_g1_i2,DN64361_c0_g1,SMAD2_RAT,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:rno:29357`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN64361_c0_g1_i3,DN64361_c0_g1,SMAD3_RAT,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:rno:25631`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN9963_c0_g3_i1,DN9963_c0_g3,.,NA,SMAD6_CHICK,Mothers against decapentaplegic homolog 6,.,NA,NA,NA,NA,GO:0005768^cellular_component^endosome,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003682^molecular_function^chromatin binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,.,.,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i3,DN3236_c0_g1,TAP1_GORGO,Antigen peptide transporter 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042825^cellular_component^TAP complex,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i2,DN3236_c0_g1,TAP1_GORGO,Antigen peptide transporter 1,TAP1_GORGO,Antigen peptide transporter 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042825^cellular_component^TAP complex,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042825^cellular_component^TAP complex,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,.,.,PF00005.27^ABC_tran^ABC transporter^2-90^E:1.4e-12,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i6,DN3236_c0_g1,TAP1_HUMAN,Antigen peptide transporter 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6890`KO:K05653,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i4,DN3236_c0_g1,TAP1_HUMAN,Antigen peptide transporter 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6890`KO:K05653,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i10,DN3236_c0_g1,TAP1_GORGO,Antigen peptide transporter 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042825^cellular_component^TAP complex,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TAP,DN3236_c0_g1_i8,DN3236_c0_g1,TAP1_HUMAN,Antigen peptide transporter 1,TAP1_GORGO,Antigen peptide transporter 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0016021^cellular_component^integral component of membrane,GO:0042825^cellular_component^TAP complex,GO:0005524^molecular_function^ATP binding,GO:0016887^molecular_function^ATPase activity,KEGG:hsa:6890`KO:K05653,COG1132^(ABC) transporter,PF00664.23^ABC_membrane^ABC transporter transmembrane region^1-82^E:8.7e-11,PF00005.27^ABC_tran^ABC transporter^147-296^E:1.6e-32,NA,NA,NA,,
no,AD,TAP,DN2304_c0_g1_i10,DN2304_c0_g1,COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^1-136^E:8.9e-24,NA,NA,NA,NA,,
no,AD,TAP,DN2304_c0_g1_i1,DN2304_c0_g1,COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^2-194^E:1.5e-38,NA,NA,NA,NA,,
no,AD,TAP,DN2304_c0_g1_i6,DN2304_c0_g1,COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",.,NA,GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",.,NA,NA,NA,NA,KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),.,NA,NA,NA,NA,,
no,AD,TAP,DN2304_c0_g1_i11,DN2304_c0_g1,COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^1-119^E:9.2e-21,NA,NA,NA,NA,,
no,AD,TAP,DN2304_c0_g1_i7,DN2304_c0_g1,COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^1-92^E:9.2e-12,NA,NA,NA,NA,,
no,AD,TAP,DN18491_c0_g1_i2,DN18491_c0_g1,MTAP_MACMU,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},MTAP_MACMU,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,KEGG:mcc:709020`KO:K00772,"COG0005^The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)",PF01048.20^PNP_UDP_1^Phosphorylase superfamily^8-252^E:5.5e-46,NA,NA,NA,NA,,
no,AD,TAP,DN18458_c0_g1_i19,DN18458_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN18458_c0_g1_i6,DN18458_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN18458_c0_g1_i1,DN18458_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN18458_c0_g1_i15,DN18458_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN18458_c0_g1_i7,DN18458_c0_g1,GPT_MOUSE,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0043231^cellular_component^intracellular membrane-bounded organelle,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:13478`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN10359_c0_g1_i1,DN10359_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_DANRE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:dre:799071`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^209-317^E:1.9e-24,NA,NA,NA,NA,,
no,AD,TAP,DN10359_c0_g1_i13,DN10359_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_DANRE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:dre:799071`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^209-272^E:3.7e-16,NA,NA,NA,NA,,
no,AD,TAP,DN10359_c0_g1_i3,DN10359_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",.,NA,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,.,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN10359_c0_g1_i12,DN10359_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_DANRE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:dre:799071`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN1769_c0_g1_i2,DN1769_c0_g1,TAP26_MOUSE,Thyroid transcription factor 1-associated protein 26,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:52713,ENOG4111ZBH^Coiled-coil domain containing 59,.,NA,NA,NA,NA,,
no,AD,TAP,DN1769_c0_g1_i4,DN1769_c0_g1,TAP26_MOUSE,Thyroid transcription factor 1-associated protein 26,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:52713,ENOG4111ZBH^Coiled-coil domain containing 59,.,NA,NA,NA,NA,,
no,AD,TAP,DN1769_c0_g1_i5,DN1769_c0_g1,TAP26_BOVIN,Thyroid transcription factor 1-associated protein 26,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:615189,ENOG4111ZBH^Coiled-coil domain containing 59,.,NA,NA,NA,NA,,
no,AD,TAP,DN1769_c0_g1_i1,DN1769_c0_g1,TAP26_MOUSE,Thyroid transcription factor 1-associated protein 26,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:mmu:52713,ENOG4111ZBH^Coiled-coil domain containing 59,.,NA,NA,NA,NA,,
no,AD,TAP,DN1769_c0_g1_i3,DN1769_c0_g1,TAP26_BOVIN,Thyroid transcription factor 1-associated protein 26,.,NA,GO:0005634^cellular_component^nucleus,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:615189,ENOG4111ZBH^Coiled-coil domain containing 59,.,NA,NA,NA,NA,,
no,AD,TAP,DN82052_c0_g1_i3,DN82052_c0_g1,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN82052_c0_g1_i1,DN82052_c0_g1,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
yes,AD,TAP,DN29756_c0_g1_i1,DN29756_c0_g1,TAP1_HUMAN,Antigen peptide transporter 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0033116^cellular_component^endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,.,NA,NA,NA,NA,KEGG:hsa:6890`KO:K05653,COG1132^(ABC) transporter,.,NA,NA,NA,NA,,
no,AD,TAP,DN45023_c0_g1_i1,DN45023_c0_g1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,.,NA,NA,NA,NA,KEGG:gga:419456`KO:K00810,"COG1575^1,4-dihydroxy-2-naphthoate octaprenyltransferase",.,NA,NA,NA,NA,,
no,AD,TAP,DN45023_c6_g1_i1,DN45023_c6_g1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,UBIA1_CHICK,UbiA prenyltransferase domain-containing protein 1,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0030173^cellular_component^integral component of Golgi membrane,GO:0005739^cellular_component^mitochondrion,GO:0016209^molecular_function^antioxidant activity,KEGG:gga:419456`KO:K00810,"COG1575^1,4-dihydroxy-2-naphthoate octaprenyltransferase",PF01040.18^UbiA^UbiA prenyltransferase family^7-117^E:2.8e-15,NA,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i4,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4092`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.8e-29,PF03166.14^MH2^MH2 domain^271-435^E:8.1e-49,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i6,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_MOUSE,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0016342^cellular_component^catenin complex,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:mmu:17131`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.2e-29,PF03166.14^MH2^MH2 domain^247-411^E:7.1e-49,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i3,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_MOUSE,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0016342^cellular_component^catenin complex,GO:0005913^cellular_component^cell-cell adherens junction,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,KEGG:mmu:17131`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.2e-29,PF03166.14^MH2^MH2 domain^247-411^E:2e-49,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i2,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4092`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.8e-29,PF03166.14^MH2^MH2 domain^272-436^E:2.3e-49,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i7,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4092`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.8e-29,PF03166.14^MH2^MH2 domain^272-436^E:2.3e-49,NA,NA,NA,,
no,AD,TAP,DN11708_c0_g1_i5,DN11708_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4092`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^117-214^E:5.8e-29,PF03166.14^MH2^MH2 domain^271-435^E:8.1e-49,NA,NA,NA,,
no,AD,TAP,DN8885_c0_g1_i3,DN8885_c0_g1,CRTAP_HUMAN,Cartilage-associated protein,CRTAP_HUMAN,Cartilage-associated protein,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005615^cellular_component^extracellular space,GO:0032991^cellular_component^protein-containing complex,GO:0061077^biological_process^chaperone-mediated protein folding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005615^cellular_component^extracellular space,GO:0032991^cellular_component^protein-containing complex,GO:0061077^biological_process^chaperone-mediated protein folding,KEGG:hsa:10491`KO:K19606,ENOG410Y7XP^Cartilage associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN8885_c0_g1_i1,DN8885_c0_g1,CRTAP_HUMAN,Cartilage-associated protein,CRTAP_HUMAN,Cartilage-associated protein,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005615^cellular_component^extracellular space,GO:0032991^cellular_component^protein-containing complex,GO:0061077^biological_process^chaperone-mediated protein folding,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005788^cellular_component^endoplasmic reticulum lumen,GO:0005615^cellular_component^extracellular space,GO:0032991^cellular_component^protein-containing complex,GO:0061077^biological_process^chaperone-mediated protein folding,KEGG:hsa:10491`KO:K19606,ENOG410Y7XP^Cartilage associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN1226_c0_g1_i1,DN1226_c0_g1,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,KEGG:gga:395132`KO:K04500,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^113-213^E:1.1e-43,PF03166.14^MH2^MH2 domain^314-484^E:3.2e-79,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g1_i3,DN5512_c0_g1,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,KEGG:mmu:57869`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^58-138^E:2.4e-15,NA,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g1_i2,DN5512_c0_g1,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,KEGG:mmu:57869`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^7-87^E:3.6e-15,NA,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g1_i6,DN5512_c0_g1,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,KEGG:mmu:57869`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^7-87^E:1.7e-15,NA,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g1_i1,DN5512_c0_g1,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,KEGG:mmu:57869`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",PF03109.16^ABC1^ABC1 family^7-87^E:3.5e-15,NA,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g2_i1,DN5512_c0_g2,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_MOUSE,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,KEGG:mmu:57869`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN5512_c0_g3_i1,DN5512_c0_g3,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:90956`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i2,DN1844_c3_g1,FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,.,NA,NA,NA,NA,KEGG:hsa:9589`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i10,DN1844_c3_g1,FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:9589`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,PF17098.5^Wtap^WTAP/Mum2p family^68-202^E:1.7e-53,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i3,DN1844_c3_g1,FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:9589`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,PF17098.5^Wtap^WTAP/Mum2p family^68-168^E:1.4e-26,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i1,DN1844_c3_g1,FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:60532`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,PF17098.5^Wtap^WTAP/Mum2p family^68-222^E:1.4e-61,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i4,DN1844_c3_g1,FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_HUMAN,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:hsa:9589`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,PF17098.5^Wtap^WTAP/Mum2p family^68-151^E:4.3e-28,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i9,DN1844_c3_g1,FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:60532`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN1844_c3_g1_i6,DN1844_c3_g1,FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},FL2D_MOUSE,Pre-mRNA-splicing regulator WTAP {ECO:0000305},GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,GO:0005737^cellular_component^cytoplasm,GO:0031965^cellular_component^nuclear membrane,GO:0016607^cellular_component^nuclear speck,GO:0005654^cellular_component^nucleoplasm,GO:0005634^cellular_component^nucleus,KEGG:mmu:60532`KO:K22824,ENOG410XNW7^wilms tumor 1 associated protein,PF17098.5^Wtap^WTAP/Mum2p family^1-65^E:2e-23,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i7,DN16008_c0_g1,.,NA,COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",.,NA,NA,NA,NA,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:rno:308453`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i24,DN16008_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_HUMAN,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:79934`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i1,DN16008_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_HUMAN,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:79934`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i3,DN16008_c0_g1,COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:rno:308453`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i25,DN16008_c0_g1,COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:rno:308453`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i5,DN16008_c0_g1,COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:rno:308453`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i15,DN16008_c0_g1,COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_RAT,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:rno:308453`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN16008_c0_g1_i11,DN16008_c0_g1,COQ8B_MOUSE,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",COQ8B_HUMAN,"Atypical kinase COQ8B, mitochondrial {ECO:0000305}",GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,GO:0005829^cellular_component^cytosol,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:79934`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN5861_c0_g1_i1,DN5861_c0_g1,COQ2_MOUSE,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,GO:0004659^molecular_function^prenyltransferase activity,GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^130-201^E:4.9e-18,NA,NA,NA,NA,,
no,AD,TAP,DN5861_c0_g1_i2,DN5861_c0_g1,COQ2_MOUSE,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_MOUSE,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,GO:0004659^molecular_function^prenyltransferase activity,GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,GO:0004659^molecular_function^prenyltransferase activity,KEGG:mmu:71883`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^149-220^E:5.9e-18,NA,NA,NA,NA,,
no,AD,TAP,DN5861_c0_g1_i3,DN5861_c0_g1,COQ2_MOUSE,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",COQ2_BOVIN,"4-hydroxybenzoate polyprenyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03189}",GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,GO:0004659^molecular_function^prenyltransferase activity,GO:0031305^cellular_component^integral component of mitochondrial inner membrane,GO:0005739^cellular_component^mitochondrion,GO:0002083^molecular_function^4-hydroxybenzoate decaprenyltransferase activity,GO:0047293^molecular_function^4-hydroxybenzoate nonaprenyltransferase activity,"GO:0016765^molecular_function^transferase activity, transferring alkyl or aryl (other than methyl) groups",KEGG:bta:504633`KO:K06125,COG0382^Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity),PF01040.18^UbiA^UbiA prenyltransferase family^82-153^E:2.3e-18,NA,NA,NA,NA,,
no,AD,TAP,DN22667_c0_g1_i2,DN22667_c0_g1,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:gga:395132`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN22667_c0_g1_i4,DN22667_c0_g1,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:gga:395132`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN22667_c0_g1_i5,DN22667_c0_g1,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:gga:395132`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN22667_c0_g1_i3,DN22667_c0_g1,SMAD3_RAT,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:rno:25631`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN778_c0_g1_i2,DN778_c0_g1,TPRN_MOUSE,Taperin,TPRN_MOUSE,Taperin,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,KEGG:mmu:97031,ENOG410ZR6R^sensory perception of sound,PF13914.6^Phostensin^Phostensin PP1-binding and SH3-binding region^426-555^E:7e-42,NA,NA,NA,NA,,
no,AD,TAP,DN54500_c0_g1_i1,DN54500_c0_g1,COQ8A_HUMAN,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",.,NA,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:56997`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN8923_c0_g1_i1,DN8923_c0_g1,TPSNR_HUMAN,Tapasin-related protein,TPSNR_HUMAN,Tapasin-related protein,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,KEGG:hsa:55080,ENOG4111SQB^TAP binding protein-like,PF07686.17^V-set^Immunoglobulin V-set domain^3-102^E:1.2e-15,PF00047.25^ig^Immunoglobulin domain^4-95^E:4.9e-05,PF13927.6^Ig_3^Immunoglobulin domain^105-194^E:3.3e-07,PF07654.15^C1-set^Immunoglobulin C1-set domain^119-198^E:3.9e-14,NA,,
no,AD,TAP,DN8923_c0_g1_i5,DN8923_c0_g1,TPSNR_HUMAN,Tapasin-related protein,TPSNR_HUMAN,Tapasin-related protein,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,KEGG:hsa:55080,ENOG4111SQB^TAP binding protein-like,PF07686.17^V-set^Immunoglobulin V-set domain^201-305^E:3.7e-16,PF00047.25^ig^Immunoglobulin domain^201-298^E:2.9e-05,NA,NA,NA,,
no,AD,TAP,DN8923_c0_g1_i4,DN8923_c0_g1,TPSNR_HUMAN,Tapasin-related protein,TPSNR_HUMAN,Tapasin-related protein,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0000139^cellular_component^Golgi membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005886^cellular_component^plasma membrane,GO:0023024^molecular_function^MHC class I protein complex binding,KEGG:hsa:55080,ENOG4111SQB^TAP binding protein-like,PF07686.17^V-set^Immunoglobulin V-set domain^201-305^E:5.8e-16,PF00047.25^ig^Immunoglobulin domain^201-298^E:4.5e-05,PF07654.15^C1-set^Immunoglobulin C1-set domain^323-401^E:1.2e-13,NA,NA,,
no,AD,TAP,DN52813_c1_g2_i1,DN52813_c1_g2,TPRN_RAT,Taperin,TPRN_RAT,Taperin,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,KEGG:rno:499749,ENOG410ZR6R^sensory perception of sound,"PF13916.6^Phostensin_N^PP1-regulatory protein, Phostensin N-terminal^35-132^E:1.6e-24",NA,NA,NA,NA,,
no,AD,TAP,DN52813_c1_g2_i2,DN52813_c1_g2,TPRN_RAT,Taperin,TPRN_RAT,Taperin,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,GO:0032420^cellular_component^stereocilium,GO:0019902^molecular_function^phosphatase binding,GO:0007605^biological_process^sensory perception of sound,GO:0120045^biological_process^stereocilium maintenance,NA,KEGG:rno:499749,ENOG410ZR6R^sensory perception of sound,"PF13916.6^Phostensin_N^PP1-regulatory protein, Phostensin N-terminal^2-55^E:3.5e-11",NA,NA,NA,NA,,
no,AD,TAP,DN10110_c0_g1_i2,DN10110_c0_g1,SND1_PONAB,Staphylococcal nuclease domain-containing protein 1,SND1_PONAB,Staphylococcal nuclease domain-containing protein 1,GO:0042470^cellular_component^melanosome,GO:0005634^cellular_component^nucleus,GO:0016442^cellular_component^RISC complex,GO:0004519^molecular_function^endonuclease activity,GO:0003676^molecular_function^nucleic acid binding,GO:0042470^cellular_component^melanosome,GO:0005634^cellular_component^nucleus,GO:0016442^cellular_component^RISC complex,GO:0004519^molecular_function^endonuclease activity,GO:0003676^molecular_function^nucleic acid binding,.,COG1525^nuclease,PF00565.17^SNase^Staphylococcal nuclease homologue^62-177^E:7.8e-15,PF00565.17^SNase^Staphylococcal nuclease homologue^231-338^E:1.4e-12,PF00565.17^SNase^Staphylococcal nuclease homologue^379-506^E:4e-11,PF00565.17^SNase^Staphylococcal nuclease homologue^564-670^E:5e-16,PF00567.24^TUDOR^Tudor domain^690-809^E:8.2e-28,,
no,AD,TAP,DN25757_c0_g1_i10,DN25757_c0_g1,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,KEGG:hsa:90956`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN25757_c0_g1_i1,DN25757_c0_g1,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:90956`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN25757_c0_g1_i2,DN25757_c0_g1,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,KEGG:hsa:90956`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN25757_c0_g1_i7,DN25757_c0_g1,ADCK2_HUMAN,Uncharacterized aarF domain-containing protein kinase 2,.,NA,GO:0016021^cellular_component^integral component of membrane,GO:0005524^molecular_function^ATP binding,GO:0004674^molecular_function^protein serine/threonine kinase activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:90956`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN48472_c0_g1_i3,DN48472_c0_g1,SMAD2_MOUSE,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:17126`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN8417_c0_g1_i3,DN8417_c0_g1,TPSN_CHICK,Tapasin,TPSN_CHICK,Tapasin,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,NA,NA,NA,.,ENOG4111QPK^TAP binding protein (tapasin),PF07686.17^V-set^Immunoglobulin V-set domain^184-287^E:3.1e-06,PF00047.25^ig^Immunoglobulin domain^300-393^E:0.00012,PF07654.15^C1-set^Immunoglobulin C1-set domain^308-387^E:4.4e-07,NA,NA,,
no,AD,TAP,DN98216_c0_g1_i3,DN98216_c0_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN98216_c0_g1_i2,DN98216_c0_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN98216_c1_g1_i1,DN98216_c1_g1,GPT_BOVIN,UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase,.,NA,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0016021^cellular_component^integral component of membrane,GO:0016020^cellular_component^membrane,GO:0046872^molecular_function^metal ion binding,GO:0008963^molecular_function^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,KEGG:bta:537812`KO:K01001,COG0472^phospho-N-acetylmuramoyl-pentapeptide-transferase activity,.,NA,NA,NA,NA,,
no,AD,TAP,DN22238_c0_g1_i7,DN22238_c0_g1,SMAD4_MOUSE,Mothers against decapentaplegic homolog 4,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:mmu:17128`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN22238_c0_g1_i6,DN22238_c0_g1,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4089`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN55910_c0_g1_i2,DN55910_c0_g1,SNPH_HUMAN,Syntaphilin,SNPH_HUMAN,Syntaphilin,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,KEGG:hsa:9751,ENOG410XQEB^syntabulin (syntaxin-interacting),.,NA,NA,NA,NA,,
no,AD,TAP,DN121894_c1_g1_i3,DN121894_c1_g1,MTAP_BOVIN,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:bta:782907`KO:K00772,"COG0005^The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN121894_c1_g1_i1,DN121894_c1_g1,MTAP_BOVIN,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:bta:782907`KO:K00772,"COG0005^The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN181347_c0_g1_i3,DN181347_c0_g1,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4089`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN181347_c0_g1_i1,DN181347_c0_g1,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4089`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN116585_c1_g1_i1,DN116585_c1_g1,JAZF1_MOUSE,Juxtaposed with another zinc finger protein 1,.,NA,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0005634^cellular_component^nucleus,GO:0017053^cellular_component^transcriptional repressor complex,GO:0046872^molecular_function^metal ion binding,.,NA,NA,NA,NA,KEGG:mmu:231986`KO:K19495,COG5189^JAZF zinc finger 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN172408_c0_g1_i1,DN172408_c0_g1,SMAD2_MOUSE,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005654^cellular_component^nucleoplasm,.,NA,NA,NA,NA,KEGG:mmu:17126`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN112691_c0_g1_i1,DN112691_c0_g1,SMAD4_HUMAN,Mothers against decapentaplegic homolog 4,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4089`KO:K04501,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN102473_c0_g1_i1,DN102473_c0_g1,COQ8A_HUMAN,"Atypical kinase COQ8A, mitochondrial {ECO:0000305}",.,NA,GO:0031314^cellular_component^extrinsic component of mitochondrial inner membrane,GO:0016021^cellular_component^integral component of membrane,GO:0005739^cellular_component^mitochondrion,GO:0043531^molecular_function^ADP binding,GO:0005524^molecular_function^ATP binding,.,NA,NA,NA,NA,KEGG:hsa:56997`KO:K08869,"COG0661^Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN161778_c0_g1_i1,DN161778_c0_g1,MTAP_XENTR,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,.,"COG0005^The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN277518_c0_g1_i1,DN277518_c0_g1,SMAD2_DANRE,Mothers against decapentaplegic homolog 2,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003700^molecular_function^DNA-binding transcription factor activity,"GO:0000981^molecular_function^DNA-binding transcription factor activity, RNA polymerase II-specific",.,NA,NA,NA,NA,KEGG:dre:30639`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN253549_c0_g1_i1,DN253549_c0_g1,CRTAP_CHICK,Cartilage-associated protein,.,NA,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005576^cellular_component^extracellular region,GO:0032991^cellular_component^protein-containing complex,GO:0061077^biological_process^chaperone-mediated protein folding,GO:1904027^biological_process^negative regulation of collagen fibril organization,.,NA,NA,NA,NA,KEGG:gga:395992`KO:K19606,ENOG410Y7XP^Cartilage associated protein,.,NA,NA,NA,NA,,
no,AD,TAP,DN254622_c0_g1_i1,DN254622_c0_g1,SMAD3_CHICK,Mothers against decapentaplegic homolog 3,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,GO:0005637^cellular_component^nuclear inner membrane,.,NA,NA,NA,NA,KEGG:gga:395132`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN206491_c0_g1_i1,DN206491_c0_g1,TAPT1_DANRE,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:dre:559710`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN250455_c0_g1_i1,DN250455_c0_g1,TAPT1_CHICK,Transmembrane anterior posterior transformation protein 1 homolog,.,NA,GO:0005813^cellular_component^centrosome,GO:0036064^cellular_component^ciliary basal body,GO:0005783^cellular_component^endoplasmic reticulum,GO:0030176^cellular_component^integral component of endoplasmic reticulum membrane,GO:0051216^biological_process^cartilage development,.,NA,NA,NA,NA,KEGG:gga:422824`KO:K23404,ENOG410XT6F^transmembrane anterior posterior transformation 1,.,NA,NA,NA,NA,,
no,AD,TAP,DN242770_c0_g1_i1,DN242770_c0_g1,SNPH_MOUSE,Syntaphilin,.,NA,GO:0030054^cellular_component^cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005881^cellular_component^cytoplasmic microtubule,GO:0016021^cellular_component^integral component of membrane,GO:0031966^cellular_component^mitochondrial membrane,.,NA,NA,NA,NA,KEGG:mmu:241727,.,.,NA,NA,NA,NA,,
no,AD,TAP,DN224264_c0_g1_i1,DN224264_c0_g1,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,SMAD7_HUMAN,Mothers against decapentaplegic homolog 7,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,GO:0005813^cellular_component^centrosome,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001650^cellular_component^fibrillar center,GO:0000790^cellular_component^nuclear chromatin,KEGG:hsa:4092`KO:K19631,ENOG410XQKU^SMAD family member,PF03165.16^MH1^MH1 domain^16-111^E:3.3e-29,NA,NA,NA,NA,,
no,AD,TAP,DN229661_c0_g1_i1,DN229661_c0_g1,SMAD5_RAT,Mothers against decapentaplegic homolog 5,.,NA,GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0005667^cellular_component^transcription factor complex,GO:0017151^molecular_function^DEAD/H-box RNA helicase binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:rno:59328`KO:K16790,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN313137_c0_g1_i1,DN313137_c0_g1,SMAD2_HUMAN,Mothers against decapentaplegic homolog 2,.,NA,GO:0032444^cellular_component^activin responsive factor complex,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0071144^cellular_component^heteromeric SMAD protein complex,GO:0000790^cellular_component^nuclear chromatin,.,NA,NA,NA,NA,KEGG:hsa:4087`KO:K04500,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
no,AD,TAP,DN302427_c0_g1_i1,DN302427_c0_g1,CFA69_HUMAN,Cilia- and flagella-associated protein 69 {ECO:0000312|HGNC:HGNC:26107},CFA69_HUMAN,Cilia- and flagella-associated protein 69 {ECO:0000312|HGNC:HGNC:26107},GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,GO:0005737^cellular_component^cytoplasm,GO:0097730^cellular_component^non-motile cilium,GO:0097225^cellular_component^sperm midpiece,GO:0030154^biological_process^cell differentiation,GO:0042048^biological_process^olfactory behavior,KEGG:hsa:79846,ENOG410XTAP^chromosome 7 open reading frame 63,.,NA,NA,NA,NA,,
no,AD,TAP,DN343298_c0_g1_i1,DN343298_c0_g1,MTAP_MOUSE,S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155},.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0005634^cellular_component^nucleus,GO:0017061^molecular_function^S-methyl-5-thioadenosine phosphorylase activity,GO:0019509^biological_process^L-methionine salvage from methylthioadenosine,.,NA,NA,NA,NA,KEGG:mmu:66902`KO:K00772,"COG0005^The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)",.,NA,NA,NA,NA,,
no,AD,TAP,DN432258_c0_g1_i1,DN432258_c0_g1,SMAD1_DANRE,Mothers against decapentaplegic homolog 1,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0005667^cellular_component^transcription factor complex,GO:0003677^molecular_function^DNA binding,GO:0003700^molecular_function^DNA-binding transcription factor activity,.,NA,NA,NA,NA,KEGG:dre:30628`KO:K04676,ENOG410XQKU^SMAD family member,.,NA,NA,NA,NA,,
yes,AD,TGFB,DN61046_c0_g1_i1,DN61046_c0_g1,TGFB3_CHICK,Transforming growth factor beta-3 proprotein,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:gga:396438`KO:K13377,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,TGFB,DN14900_c0_g1_i2,DN14900_c0_g1,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^6-89^E:1.3e-12,PF00019.20^TGF_beta^Transforming growth factor beta like domain^151-248^E:5.2e-24,NA,NA,NA,,
yes,AD,TGFB,DN14900_c0_g1_i1,DN14900_c0_g1,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^22-252^E:3e-36,PF00019.20^TGF_beta^Transforming growth factor beta like domain^314-411^E:1.4e-23,NA,NA,NA,,
yes,AD,TGFB,DN14900_c0_g1_i3,DN14900_c0_g1,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,TGFB2_CHICK,Transforming growth factor beta-2 proprotein,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,GO:0030424^cellular_component^axon,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0043025^cellular_component^neuronal cell body,.,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^22-252^E:2.2e-36,PF00019.20^TGF_beta^Transforming growth factor beta like domain^314-359^E:1.6e-10,NA,NA,NA,,
yes,AD,TGFB,DN14900_c0_g2_i1,DN14900_c0_g2,TGFB2_BOVIN,Transforming growth factor beta-2 proprotein,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005576^cellular_component^extracellular region,GO:0005615^cellular_component^extracellular space,GO:0001540^molecular_function^amyloid-beta binding,GO:0005125^molecular_function^cytokine activity,.,NA,NA,NA,NA,KEGG:bta:534069`KO:K13376,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,TGFB,DN7768_c0_g1_i4,DN7768_c0_g1,TGFB1_CHICK,Transforming growth factor beta-1 proprotein,.,NA,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005902^cellular_component^microvillus,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TGFB,DN7768_c0_g1_i1,DN7768_c0_g1,TGFB1_CHICK,Transforming growth factor beta-1 proprotein,TGFB1_CHICK,Transforming growth factor beta-1 proprotein,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005902^cellular_component^microvillus,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005902^cellular_component^microvillus,.,.,PF00688.18^TGFb_propeptide^TGF-beta propeptide^22-259^E:8.1e-36,PF00019.20^TGF_beta^Transforming growth factor beta like domain^290-387^E:6.1e-22,NA,NA,NA,,
yes,AD,TGFB,DN7768_c0_g1_i3,DN7768_c0_g1,TGFB1_CHICK,Transforming growth factor beta-1 proprotein,.,NA,GO:0009986^cellular_component^cell surface,GO:0005737^cellular_component^cytoplasm,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005902^cellular_component^microvillus,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TGFB,DN3046_c0_g1_i1,DN3046_c0_g1,TGFB3_CHICK,Transforming growth factor beta-3 proprotein,TGFB3_CHICK,Transforming growth factor beta-3 proprotein,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,KEGG:gga:396438`KO:K13377,ENOG410XT8Z^bone morphogenetic protein,PF00688.18^TGFb_propeptide^TGF-beta propeptide^124-330^E:2.9e-36,PF00019.20^TGF_beta^Transforming growth factor beta like domain^413-510^E:1.1e-23,NA,NA,NA,,
yes,AD,TGFB,DN128935_c0_g1_i3,DN128935_c0_g1,TGFB3_CHICK,Transforming growth factor beta-3 proprotein,.,NA,GO:0031012^cellular_component^extracellular matrix,GO:0005615^cellular_component^extracellular space,GO:0005125^molecular_function^cytokine activity,GO:0008083^molecular_function^growth factor activity,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:gga:396438`KO:K13377,ENOG410XT8Z^bone morphogenetic protein,.,NA,NA,NA,NA,,
yes,AD,TLR3,DN9538_c0_g1_i5,DN9538_c0_g1,TLR3_HUMAN,Toll-like receptor 3,TLR3_HUMAN,Toll-like receptor 3,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,KEGG:hsa:7098`KO:K05401,COG4886^leucine Rich Repeat,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^9-124^E:0.005,PF00560.33^LRR_1^Leucine Rich Repeat^19-41^E:9.6,PF13855.6^LRR_8^Leucine rich repeat^46-106^E:9.5e-13,PF00560.33^LRR_1^Leucine Rich Repeat^71-84^E:750,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^88-179^E:0.039,,
yes,AD,TLR3,DN9538_c0_g1_i7,DN9538_c0_g1,TLR3_HUMAN,Toll-like receptor 3,TLR3_HUMAN,Toll-like receptor 3,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,KEGG:hsa:7098`KO:K05401,COG4886^leucine Rich Repeat,PF13855.6^LRR_8^Leucine rich repeat^53-112^E:9.3e-08,PF00560.33^LRR_1^Leucine Rich Repeat^57-64^E:1800,PF00560.33^LRR_1^Leucine Rich Repeat^77-99^E:370,PF13855.6^LRR_8^Leucine rich repeat^101-159^E:7.7e-12,PF00560.33^LRR_1^Leucine Rich Repeat^102-123^E:260,,
yes,AD,TLR3,DN9538_c0_g1_i8,DN9538_c0_g1,TLR3_BOSTR,Toll-like receptor 3,TLR3_BOSTR,Toll-like receptor 3,GO:0005769^cellular_component^early endosome,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003725^molecular_function^double-stranded RNA binding,GO:0005769^cellular_component^early endosome,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0016021^cellular_component^integral component of membrane,GO:0003725^molecular_function^double-stranded RNA binding,.,.,PF00560.33^LRR_1^Leucine Rich Repeat^44-48^E:12000,PF13855.6^LRR_8^Leucine rich repeat^53-112^E:1.4e-08,PF13516.6^LRR_6^Leucine Rich repeat^53-64^E:30,PF00560.33^LRR_1^Leucine Rich Repeat^57-64^E:310,PF00560.33^LRR_1^Leucine Rich Repeat^77-99^E:64,,
yes,AD,TLR3,DN9538_c0_g1_i6,DN9538_c0_g1,TLR3_HUMAN,Toll-like receptor 3,TLR3_HUMAN,Toll-like receptor 3,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,KEGG:hsa:7098`KO:K05401,COG4886^leucine Rich Repeat,PF13855.6^LRR_8^Leucine rich repeat^53-112^E:7.9e-08,PF00560.33^LRR_1^Leucine Rich Repeat^57-64^E:1700,PF00560.33^LRR_1^Leucine Rich Repeat^77-99^E:340,PF13855.6^LRR_8^Leucine rich repeat^101-159^E:7.5e-12,PF00560.33^LRR_1^Leucine Rich Repeat^102-123^E:230,,
yes,AD,TLR3,DN9538_c0_g1_i4,DN9538_c0_g1,TLR3_HUMAN,Toll-like receptor 3,TLR3_HUMAN,Toll-like receptor 3,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,GO:0005737^cellular_component^cytoplasm,GO:0005769^cellular_component^early endosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0010008^cellular_component^endosome membrane,KEGG:hsa:7098`KO:K05401,COG4886^leucine Rich Repeat,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^9-124^E:0.005,PF00560.33^LRR_1^Leucine Rich Repeat^19-41^E:9.6,PF13855.6^LRR_8^Leucine rich repeat^46-106^E:9.5e-13,PF00560.33^LRR_1^Leucine Rich Repeat^71-84^E:750,PF13306.6^LRR_5^BspA type Leucine rich repeat region (6 copies)^88-179^E:0.039,,
yes,AD,TLR7,DN3300_c0_g1_i5,DN3300_c0_g1,TLR7_HUMAN,Toll-like receptor 7,TLR7_HUMAN,Toll-like receptor 7,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,KEGG:hsa:51284`KO:K05404,COG4886^leucine Rich Repeat,PF13516.6^LRR_6^Leucine Rich repeat^87-96^E:10000,PF00560.33^LRR_1^Leucine Rich Repeat^124-142^E:340,PF00560.33^LRR_1^Leucine Rich Repeat^169-179^E:4300,PF00560.33^LRR_1^Leucine Rich Repeat^201-218^E:25,PF13516.6^LRR_6^Leucine Rich repeat^201-213^E:26,,
yes,AD,TLR7,DN3300_c0_g1_i6,DN3300_c0_g1,TLR7_HUMAN,Toll-like receptor 7,TLR7_HUMAN,Toll-like receptor 7,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,KEGG:hsa:51284`KO:K05404,COG4886^leucine Rich Repeat,PF13516.6^LRR_6^Leucine Rich repeat^111-120^E:10000,PF00560.33^LRR_1^Leucine Rich Repeat^148-166^E:330,PF00560.33^LRR_1^Leucine Rich Repeat^193-203^E:4400,PF00560.33^LRR_1^Leucine Rich Repeat^225-244^E:13,PF13516.6^LRR_6^Leucine Rich repeat^225-237^E:27,,
yes,AD,TLR7,DN3300_c0_g1_i11,DN3300_c0_g1,TLR7_HUMAN,Toll-like receptor 7,TLR7_HUMAN,Toll-like receptor 7,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,GO:0005737^cellular_component^cytoplasm,GO:0032009^cellular_component^early phagosome,GO:0036020^cellular_component^endolysosome membrane,GO:0005783^cellular_component^endoplasmic reticulum,GO:0005789^cellular_component^endoplasmic reticulum membrane,KEGG:hsa:51284`KO:K05404,COG4886^leucine Rich Repeat,PF13516.6^LRR_6^Leucine Rich repeat^111-120^E:10000,PF00560.33^LRR_1^Leucine Rich Repeat^148-166^E:330,PF00560.33^LRR_1^Leucine Rich Repeat^193-203^E:4400,PF00560.33^LRR_1^Leucine Rich Repeat^225-244^E:13,PF13516.6^LRR_6^Leucine Rich repeat^225-237^E:27,,
no,AD,TRD,DN8263_c1_g1_i8,DN8263_c1_g1,H3_STRDR,"Histone H3, embryonic",.,NA,GO:0000786^cellular_component^nucleosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046982^molecular_function^protein heterodimerization activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TRD,DN8263_c1_g1_i10,DN8263_c1_g1,H3_STRDR,"Histone H3, embryonic",.,NA,GO:0000786^cellular_component^nucleosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046982^molecular_function^protein heterodimerization activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TRD,DN8263_c1_g1_i2,DN8263_c1_g1,H3_STRDR,"Histone H3, embryonic",.,NA,GO:0000786^cellular_component^nucleosome,GO:0005634^cellular_component^nucleus,GO:0003677^molecular_function^DNA binding,GO:0046982^molecular_function^protein heterodimerization activity,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i8,DN8271_c0_g1,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,KEGG:hsa:1787`KO:K15336,COG0270^Cytosine-specific methyltransferase,PF00145.17^DNA_methylase^C-5 cytosine-specific DNA methylase^81-137^E:1.7e-09,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i4,DN8271_c0_g1,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,KEGG:hsa:1787`KO:K15336,COG0270^Cytosine-specific methyltransferase,PF00145.17^DNA_methylase^C-5 cytosine-specific DNA methylase^81-137^E:1.7e-09,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i3,DN8271_c0_g1,TRDMT_BOVIN,tRNA (cytosine-5-)-methyltransferase,TRDMT_BOVIN,tRNA (cytosine-5-)-methyltransferase,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0008175^molecular_function^tRNA methyltransferase activity,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0008175^molecular_function^tRNA methyltransferase activity,NA,KEGG:bta:353353`KO:K15336,COG0270^Cytosine-specific methyltransferase,PF00145.17^DNA_methylase^C-5 cytosine-specific DNA methylase^5-109^E:2e-17,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i1,DN8271_c0_g1,TRDMT_MOUSE,tRNA (cytosine(38)-C(5))-methyltransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:13434`KO:K15336,COG0270^Cytosine-specific methyltransferase,.,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i9,DN8271_c0_g1,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,.,NA,NA,NA,NA,KEGG:hsa:1787`KO:K15336,COG0270^Cytosine-specific methyltransferase,.,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i7,DN8271_c0_g1,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,KEGG:hsa:1787`KO:K15336,COG0270^Cytosine-specific methyltransferase,PF00145.17^DNA_methylase^C-5 cytosine-specific DNA methylase^5-203^E:7.3e-31,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i6,DN8271_c0_g1,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,TRDMT_HUMAN,tRNA (cytosine(38)-C(5))-methyltransferase,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,GO:0005737^cellular_component^cytoplasm,GO:0005654^cellular_component^nucleoplasm,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,KEGG:hsa:1787`KO:K15336,COG0270^Cytosine-specific methyltransferase,PF00145.17^DNA_methylase^C-5 cytosine-specific DNA methylase^5-400^E:5.9e-42,NA,NA,NA,NA,,
no,AD,TRD,DN8271_c0_g1_i5,DN8271_c0_g1,TRDMT_MOUSE,tRNA (cytosine(38)-C(5))-methyltransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:13434`KO:K15336,COG0270^Cytosine-specific methyltransferase,.,NA,NA,NA,NA,,
no,AD,TRD,DN2397_c2_g1_i7,DN2397_c2_g1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,.,NA,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:617088,ENOG4111N6W^peptidyl-tRNA hydrolase domain containing 1,.,NA,NA,NA,NA,,
no,AD,TRD,DN2397_c2_g1_i2,DN2397_c2_g1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,.,NA,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:617088,ENOG4111N6W^peptidyl-tRNA hydrolase domain containing 1,.,NA,NA,NA,NA,,
no,AD,TRD,DN2397_c2_g1_i6,DN2397_c2_g1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,.,NA,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:617088,ENOG4111N6W^peptidyl-tRNA hydrolase domain containing 1,.,NA,NA,NA,NA,,
no,AD,TRD,DN2397_c2_g1_i5,DN2397_c2_g1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,KEGG:bta:617088,ENOG4111N6W^peptidyl-tRNA hydrolase domain containing 1,PF01981.16^PTH2^Peptidyl-tRNA hydrolase PTH2^13-123^E:1.8e-21,NA,NA,NA,NA,,
no,AD,TRD,DN2397_c2_g1_i4,DN2397_c2_g1,PTRD1_BOVIN,Putative peptidyl-tRNA hydrolase PTRHD1,.,NA,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,NA,NA,NA,NA,.,NA,NA,NA,NA,KEGG:bta:617088,ENOG4111N6W^peptidyl-tRNA hydrolase domain containing 1,.,NA,NA,NA,NA,,
yes,AD,TRD,DN716_c0_g1_i7,DN716_c0_g1,TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,.,.,.,NA,NA,NA,NA,,
yes,AD,TRD,DN716_c0_g1_i11,DN716_c0_g1,TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,.,.,.,NA,NA,NA,NA,,
yes,AD,TRD,DN716_c0_g1_i2,DN716_c0_g1,TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,.,.,.,NA,NA,NA,NA,,
yes,AD,TRD,DN15835_c0_g1_i2,DN15835_c0_g1,TRDC_HUMAN,T cell receptor delta constant {ECO:0000303|Ref.4},.,NA,GO:0009897^cellular_component^external side of plasma membrane,"GO:0042571^cellular_component^immunoglobulin complex, circulating",GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0003823^molecular_function^antigen binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TRD,DN138649_c0_g1_i1,DN138649_c0_g1,TRDMT_MOUSE,tRNA (cytosine(38)-C(5))-methyltransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:13434`KO:K15336,COG0270^Cytosine-specific methyltransferase,.,NA,NA,NA,NA,,
no,AD,TRD,DN138649_c0_g1_i2,DN138649_c0_g1,TRDMT_MOUSE,tRNA (cytosine(38)-C(5))-methyltransferase,.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005634^cellular_component^nucleus,GO:0003723^molecular_function^RNA binding,GO:0016428^molecular_function^tRNA (cytosine-5-)-methyltransferase activity,GO:0008175^molecular_function^tRNA methyltransferase activity,.,NA,NA,NA,NA,KEGG:mmu:13434`KO:K15336,COG0270^Cytosine-specific methyltransferase,.,NA,NA,NA,NA,,
yes,AD,TRG,DN21428_c0_g1_i3,DN21428_c0_g1,TRGV9_HUMAN,T cell receptor gamma variable 9 {ECO:0000303|Ref.3},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0042287^molecular_function^MHC protein binding,GO:0042605^molecular_function^peptide antigen binding,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TRG,DN43493_c0_g1_i1,DN43493_c0_g1,TRGV8_HUMAN,T cell receptor gamma variable 8 {ECO:0000303|Ref.2},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TRG,DN5467_c0_g1_i1,DN5467_c0_g1,TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TRG,DN5467_c0_g1_i12,DN5467_c0_g1,TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^17-88^E:7.9e-10,NA,NA,NA,NA,,
yes,AD,TRG,DN5467_c0_g1_i10,DN5467_c0_g1,TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^60-131^E:7.7e-10,NA,NA,NA,NA,,
yes,AD,TRG,DN5467_c0_g1_i4,DN5467_c0_g1,TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,.,.,PF07654.15^C1-set^Immunoglobulin C1-set domain^60-131^E:7.7e-10,NA,NA,NA,NA,,
yes,AD,TRG,DN5467_c0_g1_i3,DN5467_c0_g1,TRGC1_HUMAN,T cell receptor gamma constant 1 {ECO:0000303|Ref.3},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0016021^cellular_component^integral component of membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TRG,DN9434_c0_g1_i1,DN9434_c0_g1,TVC4_MOUSE,T-cell receptor gamma chain V region 5/10-13,TRGV3_HUMAN,T cell receptor gamma variable 3 {ECO:0000303|Ref.4},GO:0009897^cellular_component^external side of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,NA,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0005886^cellular_component^plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0042287^molecular_function^MHC protein binding,GO:0042605^molecular_function^peptide antigen binding,.,.,PF07686.17^V-set^Immunoglobulin V-set domain^63-174^E:3.2e-15,NA,NA,NA,NA,,
no,AD,TRG,DN9092_c0_g1_i10,DN9092_c0_g1,.,NA,SSP5_STRGN,Agglutinin receptor,.,NA,NA,NA,NA,GO:0005618^cellular_component^cell wall,GO:0005576^cellular_component^extracellular region,GO:0046872^molecular_function^metal ion binding,NA,NA,.,ENOG410Z98C^Streptococcal surface antigen repeat,.,NA,NA,NA,NA,,
no,AD,TRG,DN6308_c0_g1_i15,DN6308_c0_g1,RT36_BOVIN,"28S ribosomal protein S36, mitochondrial",.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0009353^cellular_component^mitochondrial oxoglutarate dehydrogenase complex,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0006103^biological_process^2-oxoglutarate metabolic process,GO:0055114^biological_process^oxidation-reduction process,.,NA,NA,NA,NA,KEGG:bta:613835`KO:K17414,ENOG410XTRG^Mitochondrial ribosomal protein S36,.,NA,NA,NA,NA,,
no,AD,TRG,DN6308_c0_g1_i10,DN6308_c0_g1,RT36_BOVIN,"28S ribosomal protein S36, mitochondrial",RT36_BOVIN,"28S ribosomal protein S36, mitochondrial",GO:0005743^cellular_component^mitochondrial inner membrane,GO:0009353^cellular_component^mitochondrial oxoglutarate dehydrogenase complex,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0006103^biological_process^2-oxoglutarate metabolic process,GO:0055114^biological_process^oxidation-reduction process,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0009353^cellular_component^mitochondrial oxoglutarate dehydrogenase complex,GO:0005763^cellular_component^mitochondrial small ribosomal subunit,GO:0006103^biological_process^2-oxoglutarate metabolic process,GO:0055114^biological_process^oxidation-reduction process,KEGG:bta:613835`KO:K17414,ENOG410XTRG^Mitochondrial ribosomal protein S36,.,NA,NA,NA,NA,,
yes,AD,TRG,DN21692_c0_g1_i5,DN21692_c0_g1,TRGV9_HUMAN,T cell receptor gamma variable 9 {ECO:0000303|Ref.3},TRGV9_HUMAN,T cell receptor gamma variable 9 {ECO:0000303|Ref.3},GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0042287^molecular_function^MHC protein binding,GO:0042605^molecular_function^peptide antigen binding,GO:0009897^cellular_component^external side of plasma membrane,GO:0005887^cellular_component^integral component of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0042287^molecular_function^MHC protein binding,GO:0042605^molecular_function^peptide antigen binding,.,.,PF00047.25^ig^Immunoglobulin domain^26-122^E:2e-05,PF07686.17^V-set^Immunoglobulin V-set domain^32-119^E:1.3e-13,NA,NA,NA,,
no,AD,TRG,DN32826_c0_g1_i10,DN32826_c0_g1,SSP5_STRGN,Agglutinin receptor,.,NA,GO:0005618^cellular_component^cell wall,GO:0005576^cellular_component^extracellular region,GO:0046872^molecular_function^metal ion binding,NA,NA,.,NA,NA,NA,NA,.,ENOG410Z98C^Streptococcal surface antigen repeat,.,NA,NA,NA,NA,,
yes,AD,TRG,DN24287_c0_g2_i1,DN24287_c0_g2,TRGV4_HUMAN,T cell receptor gamma variable 4 {ECO:0000303|Ref.2},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
yes,AD,TRG,DN26509_c1_g2_i6,DN26509_c1_g2,TRGV8_HUMAN,T cell receptor gamma variable 8 {ECO:0000303|Ref.2},.,NA,GO:0009897^cellular_component^external side of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,GO:0045087^biological_process^innate immune response,NA,.,NA,NA,NA,NA,.,.,.,NA,NA,NA,NA,,
no,AD,TRG,DN26509_c1_g2_i3,DN26509_c1_g2,KV6A9_MOUSE,Ig kappa chain V-VI region NQ6-8.3.1,TRGV8_HUMAN,T cell receptor gamma variable 8 {ECO:0000303|Ref.2},GO:0005615^cellular_component^extracellular space,GO:0019814^cellular_component^immunoglobulin complex,GO:0002250^biological_process^adaptive immune response,GO:0006955^biological_process^immune response,GO:0002377^biological_process^immunoglobulin production,GO:0009897^cellular_component^external side of plasma membrane,GO:0042101^cellular_component^T cell receptor complex,GO:0002250^biological_process^adaptive immune response,GO:0045087^biological_process^innate immune response,NA,.,.,PF07686.17^V-set^Immunoglobulin V-set domain^5-89^E:9.2e-12,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i11,DN3886_c0_g1,ICT1_HUMAN,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",.,NA,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,.,NA,NA,NA,NA,KEGG:hsa:3396`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i3,DN3886_c0_g1,ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,KEGG:aml:100466987`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^75-166^E:3.4e-16,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i6,DN3886_c0_g1,ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,.,NA,NA,NA,NA,KEGG:aml:100466987`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i2,DN3886_c0_g1,ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",ICT1_BOVIN,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,GO:0005743^cellular_component^mitochondrial inner membrane,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",KEGG:bta:515465`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^75-100^E:5.4e-07,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i5,DN3886_c0_g1,ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,.,NA,NA,NA,NA,KEGG:aml:100466987`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN3886_c0_g1_i12,DN3886_c0_g1,ICT1_AILME,"Peptidyl-tRNA hydrolase ICT1, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0004045^molecular_function^aminoacyl-tRNA hydrolase activity,"GO:0016150^molecular_function^translation release factor activity, codon nonspecific",GO:0070126^biological_process^mitochondrial translational termination,.,NA,NA,NA,NA,KEGG:aml:100466987`KO:K15033,COG1186^Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN50857_c0_g1_i1,DN50857_c0_g1,GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:8833`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN3999_c0_g1_i2,DN3999_c0_g1,GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,KEGG:hsa:8833`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),PF00117.28^GATase^Glutamine amidotransferase class-I^32-211^E:8.2e-40,PF07722.13^Peptidase_C26^Peptidase C26^98-194^E:1.2e-11,PF02540.17^NAD_synthase^NAD synthase^227-302^E:7e-09,PF06508.13^QueC^Queuosine biosynthesis protein QueC^240-302^E:3.1e-07,PF03054.16^tRNA_Me_trans^tRNA methyl transferase^240-307^E:2.1e-05,,
no,AD,UAA,DN3999_c0_g1_i4,DN3999_c0_g1,GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],GUAA_MOUSE,GMP synthase [glutamine-hydrolyzing],GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,KEGG:mmu:229363`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),PF00117.28^GATase^Glutamine amidotransferase class-I^63-242^E:2.4e-40,PF07722.13^Peptidase_C26^Peptidase C26^129-225^E:4.8e-12,PF02540.17^NAD_synthase^NAD synthase^258-334^E:5.4e-09,PF02568.14^ThiI^Thiamine biosynthesis protein (ThiI)^269-348^E:9.6e-05,PF00733.21^Asn_synthase^Asparagine synthase^270-326^E:0.00031,,
no,AD,UAA,DN11866_c0_g1_i5,DN11866_c0_g1,NDUAA_PONPY,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial",NDUAA_PONPY,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial",GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,"GO:0006120^biological_process^mitochondrial electron transport, NADH to ubiquinone",GO:0032981^biological_process^mitochondrial respiratory chain complex I assembly,NA,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,"GO:0006120^biological_process^mitochondrial electron transport, NADH to ubiquinone",GO:0032981^biological_process^mitochondrial respiratory chain complex I assembly,NA,.,.,PF01712.19^dNK^Deoxynucleoside kinase^77-288^E:1.7e-33,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i2,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",RF1M_HUMAN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,GO:0003747^molecular_function^translation release factor activity,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,KEGG:hsa:9617`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i3,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^90-289^E:2.2e-50,PF00472.20^RF-1^RF-1 domain^297-406^E:7.6e-40,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i7,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i10,DN12226_c0_g1,RF1M_HUMAN,"Peptide chain release factor 1, mitochondrial",RF1M_HUMAN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,GO:0003747^molecular_function^translation release factor activity,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,GO:0003747^molecular_function^translation release factor activity,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,KEGG:hsa:9617`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^98-249^E:2.3e-29,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i11,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^90-289^E:2.2e-50,PF00472.20^RF-1^RF-1 domain^297-406^E:7.6e-40,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i9,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i6,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i4,DN12226_c0_g1,RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",RF1M_BOVIN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:504754`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^90-289^E:2.2e-50,PF00472.20^RF-1^RF-1 domain^297-406^E:7.6e-40,NA,NA,NA,,
no,AD,UAA,DN12226_c0_g1_i8,DN12226_c0_g1,RF1M_HUMAN,"Peptide chain release factor 1, mitochondrial",RF1M_HUMAN,"Peptide chain release factor 1, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,GO:0003747^molecular_function^translation release factor activity,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,GO:0003747^molecular_function^translation release factor activity,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,KEGG:hsa:9617`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^98-189^E:8.8e-06,NA,NA,NA,NA,,
no,AD,UAA,DN20573_c0_g1_i4,DN20573_c0_g1,GUAA_MOUSE,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:mmu:229363`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN20573_c0_g1_i13,DN20573_c0_g1,GUAA_MOUSE,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:mmu:229363`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN20573_c0_g1_i9,DN20573_c0_g1,GUAA_MOUSE,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:mmu:229363`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN20573_c0_g1_i5,DN20573_c0_g1,GUAA_MOUSE,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:mmu:229363`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN45199_c0_g1_i2,DN45199_c0_g1,GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:8833`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN45199_c0_g1_i1,DN45199_c0_g1,GUAA_HUMAN,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,GO:0016462^molecular_function^pyrophosphatase activity,.,NA,NA,NA,NA,KEGG:hsa:8833`KO:K01951,COG0518^Catalyzes the synthesis of GMP from XMP (By similarity)`COG0519^Catalyzes the synthesis of GMP from XMP (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN55558_c0_g1_i4,DN55558_c0_g1,GUAA_RAT,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0019899^molecular_function^enzyme binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,.,NA,NA,NA,NA,KEGG:rno:295088`KO:K01951,.,.,NA,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i4,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^2-100^E:2.5e-43,PF00472.20^RF-1^RF-1 domain^109-190^E:6.1e-31,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i7,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^2-100^E:4.7e-43,PF00472.20^RF-1^RF-1 domain^109-217^E:1.6e-38,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i6,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:2.2e-13,PF00472.20^RF-1^RF-1 domain^38-119^E:1.9e-31,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i14,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:4.1e-13,PF00472.20^RF-1^RF-1 domain^38-146^E:7.2e-39,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i5,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:4.1e-13,PF00472.20^RF-1^RF-1 domain^38-146^E:7.2e-39,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i8,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:4.1e-13,PF00472.20^RF-1^RF-1 domain^38-146^E:7.2e-39,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i10,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i15,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:2.2e-13,PF00472.20^RF-1^RF-1 domain^38-119^E:1.9e-31,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i16,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_HUMAN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005759^cellular_component^mitochondrial matrix,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,KEGG:hsa:54516`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i3,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:4.1e-13,PF00472.20^RF-1^RF-1 domain^38-146^E:7.2e-39,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i17,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF03462.18^PCRF^PCRF domain^1-29^E:4.1e-13,PF00472.20^RF-1^RF-1 domain^38-146^E:7.2e-39,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i12,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN1843_c0_g1_i13,DN1843_c0_g1,RF1ML_BOVIN,"Peptide chain release factor 1-like, mitochondrial",.,NA,GO:0005739^cellular_component^mitochondrion,GO:0043022^molecular_function^ribosome binding,"GO:0016149^molecular_function^translation release factor activity, codon specific",GO:0070126^biological_process^mitochondrial translational termination,GO:0006415^biological_process^translational termination,.,NA,NA,NA,NA,KEGG:bta:534354`KO:K02835,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN22684_c0_g1_i1,DN22684_c0_g1,NDUAA_MOUSE,"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial",.,NA,GO:0005737^cellular_component^cytoplasm,GO:0005759^cellular_component^mitochondrial matrix,GO:0005747^cellular_component^mitochondrial respiratory chain complex I,GO:0005739^cellular_component^mitochondrion,GO:0043209^cellular_component^myelin sheath,.,NA,NA,NA,NA,KEGG:mmu:67273`KO:K03954,ENOG41101CN^NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex,.,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i5,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",CL065_DANRE,"Probable peptide chain release factor C12orf65 homolog, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0003747^molecular_function^translation release factor activity,NA,NA,NA,KEGG:dre:100004874`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^53-153^E:2.1e-22,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i4,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:91574`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i8,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",CL065_DANRE,"Probable peptide chain release factor C12orf65 homolog, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0003747^molecular_function^translation release factor activity,NA,NA,NA,KEGG:dre:100004874`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^53-153^E:2.1e-22,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i7,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",.,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,.,NA,NA,NA,NA,KEGG:hsa:91574`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),.,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i1,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,KEGG:hsa:91574`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^64-105^E:8.1e-10,NA,NA,NA,NA,,
no,AD,UAA,DN35538_c0_g1_i2,DN35538_c0_g1,CL065_HUMAN,"Probable peptide chain release factor C12orf65, mitochondrial",CL065_DANRE,"Probable peptide chain release factor C12orf65 homolog, mitochondrial",GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0005739^cellular_component^mitochondrion,GO:0003747^molecular_function^translation release factor activity,NA,NA,GO:0005762^cellular_component^mitochondrial large ribosomal subunit,GO:0003747^molecular_function^translation release factor activity,NA,NA,NA,KEGG:dre:100004874`KO:K23498,COG0216^Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity),PF00472.20^RF-1^RF-1 domain^53-153^E:2.1e-22,NA,NA,NA,NA,,
no,AD,UAA,DN30459_c0_g1_i3,DN30459_c0_g1,GUAA_RAT,GMP synthase [glutamine-hydrolyzing],.,NA,GO:0005829^cellular_component^cytosol,GO:0005524^molecular_function^ATP binding,GO:0019899^molecular_function^enzyme binding,GO:0003922^molecular_function^GMP synthase (glutamine-hydrolyzing) activity,GO:0003921^molecular_function^GMP synthase activity,.,NA,NA,NA,NA,KEGG:rno:295088`KO:K01951,.,.,NA,NA,NA,NA,,
Yes,,XCL1,DN5624_c0_g2_i1,DN5624_c0_g2,XCL1_RAT,Lymphotactin,XCL1_RAT,Lymphotactin,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,GO:0005615^cellular_component^extracellular space,GO:0048020^molecular_function^CCR chemokine receptor binding,GO:0008009^molecular_function^chemokine activity,GO:0071346^biological_process^cellular response to interferon-gamma,GO:0071347^biological_process^cellular response to interleukin-1,KEGG:rno:171371`KO:K05507,ENOG4111C3M^Chemokine (C motif) ligand,"PF00048.20^IL8^Small cytokines (intecrine/chemokine), interleukin-8 like^51-102^E:4.7e-10",NA,NA,NA,NA,,
yes,AD,ZAP,DN443_c1_g1_i6,DN443_c1_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,PF13912.6^zf-C2H2_6^C2H2-type zinc finger^7-30^E:0.044,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^8-30^E:0.00038","PF00096.26^zf-C2H2^Zinc finger, C2H2 type^123-145^E:0.00057",NA,NA,,
yes,AD,ZAP,DN443_c1_g1_i5,DN443_c1_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,PF13912.6^zf-C2H2_6^C2H2-type zinc finger^39-62^E:0.073,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^40-62^E:0.00062","PF00096.26^zf-C2H2^Zinc finger, C2H2 type^155-177^E:0.00094","PF00096.26^zf-C2H2^Zinc finger, C2H2 type^183-205^E:4.3e-05",PF12874.7^zf-met^Zinc-finger of C2H2 type^183-203^E:0.044,,
yes,AD,ZAP,DN443_c1_g1_i4,DN443_c1_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^9-28^E:0.0074",PF13912.6^zf-C2H2_6^C2H2-type zinc finger^39-62^E:0.031,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^40-62^E:0.00026","PF00096.26^zf-C2H2^Zinc finger, C2H2 type^155-177^E:0.0004",NA,,
yes,AD,ZAP,DN443_c1_g1_i3,DN443_c1_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,PF00651.31^BTB^BTB/POZ domain^38-137^E:1.9e-18,PF13912.6^zf-C2H2_6^C2H2-type zinc finger^290-313^E:0.11,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^291-313^E:0.00096","PF00096.26^zf-C2H2^Zinc finger, C2H2 type^406-428^E:0.0014",NA,,
yes,AD,ZAP,DN443_c1_g1_i2,DN443_c1_g1,TZAP_PONAB,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005634^cellular_component^nucleus,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0046872^molecular_function^metal ion binding,GO:0044212^molecular_function^transcription regulatory region DNA binding,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,PF13894.6^zf-C2H2_4^C2H2-type zinc finger^16-39^E:0.00044,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^16-39^E:0.012",PF13894.6^zf-C2H2_4^C2H2-type zinc finger^46-67^E:0.00029,"PF00096.26^zf-C2H2^Zinc finger, C2H2 type^46-67^E:3.7e-05",PF13913.6^zf-C2HC_2^zinc-finger of a C2HC-type^47-65^E:0.16,,
yes,AD,ZAP,DN6081_c0_g1_i7,DN6081_c0_g1,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:7535`KO:K07360,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN6081_c0_g1_i1,DN6081_c0_g1,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,.,NA,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,.,NA,NA,NA,NA,KEGG:hsa:7535`KO:K07360,COG0515^Serine Threonine protein kinase,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN6081_c0_g1_i2,DN6081_c0_g1,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:7535`KO:K07360,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^10-87^E:1.5e-16,PF00017.24^SH2^SH2 domain^163-238^E:1e-22,PF00069.25^Pkinase^Protein kinase domain^329-529^E:1.6e-44,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^331-530^E:1e-73,NA,,
yes,AD,ZAP,DN6081_c0_g1_i4,DN6081_c0_g1,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,KEGG:hsa:7535`KO:K07360,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^50-119^E:5.3e-21,NA,NA,NA,NA,,
yes,AD,ZAP,DN6081_c0_g1_i5,DN6081_c0_g1,ZAP70_HUMAN,Tyrosine-protein kinase ZAP-70,ZAP70_MOUSE,Tyrosine-protein kinase ZAP-70,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0005886^cellular_component^plasma membrane,GO:0005911^cellular_component^cell-cell junction,GO:0005737^cellular_component^cytoplasm,GO:0005829^cellular_component^cytosol,GO:0001772^cellular_component^immunological synapse,GO:0016020^cellular_component^membrane,KEGG:mmu:22637`KO:K07360,COG0515^Serine Threonine protein kinase,PF00017.24^SH2^SH2 domain^10-87^E:1.8e-16,PF00017.24^SH2^SH2 domain^163-238^E:1.2e-22,PF00069.25^Pkinase^Protein kinase domain^329-575^E:5.8e-48,PF07714.17^Pkinase_Tyr^Protein tyrosine kinase^331-579^E:6.7e-92,NA,,
no,AD,ZAP,DN11717_c0_g1_i2,DN11717_c0_g1,MYZAP_HUMAN,Myocardial zonula adherens protein,.,NA,GO:0030054^cellular_component^cell junction,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0031674^cellular_component^I band,GO:0030018^cellular_component^Z disc,.,NA,NA,NA,NA,KEGG:hsa:100820829`KEGG:hsa:145781`KO:K22031,ENOG410ZUQB^GRINL1A complex locus,.,NA,NA,NA,NA,,
no,AD,ZAP,DN11717_c0_g1_i3,DN11717_c0_g1,MYZAP_HUMAN,Myocardial zonula adherens protein,.,NA,GO:0030054^cellular_component^cell junction,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0031674^cellular_component^I band,GO:0030018^cellular_component^Z disc,.,NA,NA,NA,NA,KEGG:hsa:100820829`KEGG:hsa:145781`KO:K22031,ENOG410ZUQB^GRINL1A complex locus,.,NA,NA,NA,NA,,
no,AD,ZAP,DN11717_c0_g1_i6,DN11717_c0_g1,MYZAP_HUMAN,Myocardial zonula adherens protein,.,NA,GO:0030054^cellular_component^cell junction,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0031674^cellular_component^I band,GO:0030018^cellular_component^Z disc,.,NA,NA,NA,NA,KEGG:hsa:100820829`KEGG:hsa:145781`KO:K22031,ENOG410ZUQB^GRINL1A complex locus,.,NA,NA,NA,NA,,
no,AD,ZAP,DN11717_c0_g2_i2,DN11717_c0_g2,MYZAP_HUMAN,Myocardial zonula adherens protein,MYZAP_HUMAN,Myocardial zonula adherens protein,GO:0030054^cellular_component^cell junction,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0031674^cellular_component^I band,GO:0030018^cellular_component^Z disc,GO:0030054^cellular_component^cell junction,GO:0030864^cellular_component^cortical actin cytoskeleton,GO:0031234^cellular_component^extrinsic component of cytoplasmic side of plasma membrane,GO:0031674^cellular_component^I band,GO:0030018^cellular_component^Z disc,KEGG:hsa:100820829`KEGG:hsa:145781`KO:K22031,ENOG410ZUQB^GRINL1A complex locus,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN69807_c0_g1_i3,DN69807_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i4,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i8,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i1,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i3,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i2,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,
yes,AD,ZAP,DN15947_c0_g1_i7,DN15947_c0_g1,TZAP_MOUSE,Telomere zinc finger-associated protein {ECO:0000250|UniProtKB:P10074},.,NA,"GO:0000781^cellular_component^chromosome, telomeric region",GO:0005829^cellular_component^cytosol,GO:0005654^cellular_component^nucleoplasm,GO:0003691^molecular_function^double-stranded telomeric DNA binding,GO:0042802^molecular_function^identical protein binding,.,NA,NA,NA,NA,KEGG:mmu:100090`KO:K10519,COG5048^Zinc finger protein,.,NA,NA,NA,NA,,