no AM, no metric: Change in relation to what other measurement?
Zusätzlich investigator reported outcomes und Effectiveness assessed at 3 months: lesion complete response
rate
no measure for response vs. Stable disease
No AM; Two further secondary outcomes mentioned in paper
Follow up after 3.5 instead of 3 years. Outcome 7 (remission rate) not reported
no AM, no time frame, no metric, no measure
no AM, no metric, no measure of clinical response
no AM, no metric, no measure, no time frame
Additional scales: KHQ and SF-36. MCC (that is outcome 3) not assessed. Different time frames for number of micturitions.
Registration: no AM, no measure (definition of blood test); Paper: Endpoint 2 of 3 not assessed. Unclear to the rater whether the other endpoints were assessed.
Explicitly mentioned that no AM could be conducted
definitions of "response", "stable disease" etc. missing
no AM, no measure, no type of outcome (insufficient for checking)
unclear to this assessor what is meant by "equal results" and what variables are of interest here
some additional outcomes given in description without details
no AM; not reported due to data sparsity (metioned as limitation in paper)
No intermediate time frames reported, only the last one
unclear to this assesor how missed indications can be recorded
No AM, no time frame, no metric, no measure
Aggregation Method missing; Article: One day difference in follow-up length
no measure (unclear if the CT parameters are pre-defined)
no measure; best response reported only at end of study, not at all timepoints that are mentioned in register
no AM, no time frame ("selected time points")
Aggregation Method missing; Article: Not reported.
info on secondary endpoints only in objectives section
no AM, no time frame, no measure, no metric
secondary endpoints are mentioned in the secondary objectives but no details given
no AM; SCORAD was assessed according to article, but not reported

NCT: Anticipated 180 ICTRP: 180 DRKS: NA
NCT: Anticipated 810 ICTRP: 810 DRKS: NA
NCT: Anticipated 280 ICTRP: 280 DRKS: NA
NCT: Anticipated 150 ICTRP: 150 DRKS: NA
NCT: Anticipated 200 ICTRP: 200 DRKS: NA
NCT: Anticipated 250 ICTRP: 250 DRKS: NA
NCT: Anticipated 240 ICTRP: 240 DRKS: NA
NCT: Anticipated 106 ICTRP: 106 DRKS: NA
NCT: Anticipated 176 ICTRP: 176 DRKS: NA
NCT: Anticipated 500 ICTRP: 500 DRKS: NA
NCT: Anticipated 960 ICTRP: 960 DRKS: NA
NCT: Anticipated 1000 ICTRP: 1000 DRKS: NA
NCT: Anticipated 450 ICTRP: 450 DRKS: NA
NCT: Anticipated 210 ICTRP: 210 DRKS: NA
NCT: Anticipated 3700 ICTRP: 3700 DRKS: NA
NCT: Anticipated 1234 ICTRP: 1234 DRKS: NA
NCT: Anticipated 155 ICTRP: 155 DRKS: NA
NCT: Anticipated 220 ICTRP: 220 DRKS: NA
NCT: Anticipated 120 ICTRP: 120 DRKS: NA
NCT: Anticipated 604 ICTRP: 604 DRKS: NA
NCT: Anticipated 192 ICTRP: 192 DRKS: NA
NCT: Anticipated 1500 ICTRP: 1500 DRKS: NA
NCT: Anticipated 300 ICTRP: 300 DRKS: NA
NCT: Anticipated 100 ICTRP: 100 DRKS: NA
NCT: Anticipated 50000 ICTRP: 50000 DRKS: NA
NCT: Anticipated 138 ICTRP: 138 DRKS: NA
NCT: Actual 696 ICTRP: 850 DRKS: [---]* 850
NCT: Anticipated 360 ICTRP: 360 DRKS: NA
NCT: Anticipated 720 ICTRP: 720 DRKS: NA
NCT: Anticipated 166 ICTRP: 166 DRKS: NA
NCT: Anticipated 256 ICTRP: 256 DRKS: NA
NCT: NA ICTRP: 100 DRKS: Tatsächlich 100
NCT: NA ICTRP: 110 DRKS: Tatsächlich 110
NCT: NA ICTRP: 892 DRKS: Tatsächlich 892
NCT: NA ICTRP: 3746 DRKS: Tatsächlich 3746
NCT: NA ICTRP: 130 DRKS: Tatsächlich 130
NCT: NA ICTRP: 200 DRKS: Tatsächlich 200
NCT: NA ICTRP: 960 DRKS: Tatsächlich 960
NCT: NA ICTRP: 250 DRKS: Tatsächlich 250
NCT: NA ICTRP: 139 DRKS: Tatsächlich 139
NCT: NA ICTRP: 22000 DRKS: Tatsächlich 22000
NCT: NA ICTRP: 52500 DRKS: Tatsächlich 47400
NCT: NA ICTRP: 260 DRKS: Tatsächlich 260
NCT: NA ICTRP: 220 DRKS: Tatsächlich 220
NCT: NA ICTRP: 141 DRKS: Tatsächlich 141
NCT: NA ICTRP: 180 DRKS: Tatsächlich 180
NCT: NA ICTRP: 280 DRKS: Tatsächlich 280
NCT: NA ICTRP: 108 DRKS: Tatsächlich 108
NCT: NA ICTRP: 125 DRKS: Tatsächlich 125
NCT: NA ICTRP: 90000 DRKS: Tatsächlich 90000