<br>        Inclusion Criteria:<br><br>          -  adult patients, >=18 years of age;<br><br>          -  positive Hepatitis B surface antigen (HBsAg) for >6 months, positive HBeAg, HBV DNA<br>             >500,000 copies/mL, and anti-HBs negative;<br><br>          -  liver disease consistent with Chronic Hepatitis B.<br><br>        Exclusion Criteria:<br><br>          -  antiviral therapy for CHB within previous 6 months;<br><br>          -  co-infection with Hepatitis A virus (HAV), Hepatitis C virus (HCV), Hepatitis D virus<br>             (HDV) or Human immuno deficiency virus (HIV);<br><br>          -  evidence of decompensated liver disease;<br><br>          -  medical condition associated with chronic liver disease.<br>      ;<br>        Inclusion Criteria:<br><br>          -  adult patients, >=18 years of age;<br><br>          -  positive Hepatitis B surface antigen (HBsAg) for >6 months, positive HBeAg, HBV DNA<br>             >500,000 copies/mL, and anti-HBs negative;<br><br>          -  liver disease consistent with Chronic Hepatitis B.<br><br>        Exclusion Criteria:<br><br>          -  antiviral therapy for CHB within previous 6 months;<br><br>          -  co-infection with Hepatitis A virus (HAV), Hepatitis C virus (HCV), Hepatitis D virus<br>             (HDV) or Human immuno deficiency virus (HIV);<br><br>          -  evidence of decompensated liver disease;<br><br>          -  medical condition associated with chronic liver disease.<br>      ;<br>        Inclusion Criteria:<br><br>          -  adult patients, >=18 years of age;<br><br>          -  positive Hepatitis B surface antigen (HBsAg) for >6 months, positive HBeAg, HBV DNA<br>             >500,000 copies/mL, and anti-HBs negative;<br><br>          -  liver disease consistent with Chronic Hepatitis B.<br><br>        Exclusion Criteria:<br><br>          -  antiviral therapy for CHB within previous 6 months;<br><br>          -  co-infection with Hepatitis A virus (HAV), Hepatitis C virus (HCV), Hepatitis D virus<br>             (HDV) or Human immuno deficiency virus (HIV);<br><br>          -  evidence of decompensated liver disease;<br><br>          -  medical condition associated with chronic liver disease.<br>      ;<br>        Inclusion Criteria:<br><br>          -  adult patients, >=18 years of age;<br><br>          -  positive Hepatitis B surface antigen (HBsAg) for >6 months, positive HBeAg, HBV DNA<br>             >500,000 copies/mL, and anti-HBs negative;<br><br>          -  liver disease consistent with Chronic Hepatitis B.<br><br>        Exclusion Criteria:<br><br>          -  antiviral therapy for CHB within previous 6 months;<br><br>          -  co-infection with Hepatitis A virus (HAV), Hepatitis C virus (HCV), Hepatitis D virus<br>             (HDV) or Human immuno deficiency virus (HIV);<br><br>          -  evidence of decompensated liver disease;<br><br>          -  medical condition associated with chronic liver disease.<br>