<br>        Inclusion Criteria:<br><br>          -  A liver biopsy required within 3 years prior to screening unless the patient has a<br>             contraindication for a liver biopsy<br><br>          -  Patients with bridging fibrosis or cirrhosis and without a liver biopsy result within<br>             2 years prior screening must have an ultrasound taken within 2 months prior to the<br>             screening visit or during screening with no findings suspicious for hepatocellular<br>             carcinoma (HCC)<br><br>          -  Genotype-1 hepatitis C virus (HCV) infection<br><br>          -  Plasma HCV ribonucleic acid (RNA) of more than 10,000 IU per mL<br><br>          -  Documented human immunodeficiency virus-type 1 (HIV-1) infection at least 6 months<br>             prior to screening<br><br>        Exclusion Criteria:<br><br>          -  Patient showing evidence of hepatic decompensation (ie, history or current evidence of<br>             ascites, bleeding varices or hepatic encephalopathy, albumin serum concentration less<br>             than 3.3 gm per dL, prolonged prothrombin time [PT] expressed as international<br>             normalized ratio [INR] more than 1.5)<br><br>          -  Any liver disease of non-HCV etiology<br><br>          -  Co-infection with hepatitis B virus (hepatitis B surface antigen [HBsAg] positive)<br><br>          -  An acute HIV-1 infection; or HIV-2 infection<br><br>          -  Change in antiretroviral (ARV) regimen within the last 4 weeks prior screening<br>      ;<br>        Inclusion Criteria:<br><br>          -  A liver biopsy required within 3 years prior to screening unless the patient has a<br>             contraindication for a liver biopsy<br><br>          -  Patients with bridging fibrosis or cirrhosis and without a liver biopsy result within<br>             2 years prior screening must have an ultrasound taken within 2 months prior to the<br>             screening visit or during screening with no findings suspicious for hepatocellular<br>             carcinoma (HCC)<br><br>          -  Genotype-1 hepatitis C virus (HCV) infection<br><br>          -  Plasma HCV ribonucleic acid (RNA) of more than 10,000 IU per mL<br><br>          -  Documented human immunodeficiency virus-type 1 (HIV-1) infection at least 6 months<br>             prior to screening<br><br>        Exclusion Criteria:<br><br>          -  Patient showing evidence of hepatic decompensation (ie, history or current evidence of<br>             ascites, bleeding varices or hepatic encephalopathy, albumin serum concentration less<br>             than 3.3 gm per dL, prolonged prothrombin time [PT] expressed as international<br>             normalized ratio [INR] more than 1.5)<br><br>          -  Any liver disease of non-HCV etiology<br><br>          -  Co-infection with hepatitis B virus (hepatitis B surface antigen [HBsAg] positive)<br><br>          -  An acute HIV-1 infection; or HIV-2 infection<br><br>          -  Change in antiretroviral (ARV) regimen within the last 4 weeks prior screening<br>      ;<br>        Inclusion Criteria:<br><br>          -  A liver biopsy required within 3 years prior to screening unless the patient has a<br>             contraindication for a liver biopsy<br><br>          -  Patients with bridging fibrosis or cirrhosis and without a liver biopsy result within<br>             2 years prior screening must have an ultrasound taken within 2 months prior to the<br>             screening visit or during screening with no findings suspicious for hepatocellular<br>             carcinoma (HCC)<br><br>          -  Genotype-1 hepatitis C virus (HCV) infection<br><br>          -  Plasma HCV ribonucleic acid (RNA) of more than 10,000 IU per mL<br><br>          -  Documented human immunodeficiency virus-type 1 (HIV-1) infection at least 6 months<br>             prior to screening<br><br>        Exclusion Criteria:<br><br>          -  Patient showing evidence of hepatic decompensation (ie, history or current evidence of<br>             ascites, bleeding varices or hepatic encephalopathy, albumin serum concentration less<br>             than 3.3 gm per dL, prolonged prothrombin time [PT] expressed as international<br>             normalized ratio [INR] more than 1.5)<br><br>          -  Any liver disease of non-HCV etiology<br><br>          -  Co-infection with hepatitis B virus (hepatitis B surface antigen [HBsAg] positive)<br><br>          -  An acute HIV-1 infection; or HIV-2 infection<br><br>          -  Change in antiretroviral (ARV) regimen within the last 4 weeks prior screening<br>      ;<br>        Inclusion Criteria:<br><br>          -  A liver biopsy required within 3 years prior to screening unless the patient has a<br>             contraindication for a liver biopsy<br><br>          -  Patients with bridging fibrosis or cirrhosis and without a liver biopsy result within<br>             2 years prior screening must have an ultrasound taken within 2 months prior to the<br>             screening visit or during screening with no findings suspicious for hepatocellular<br>             carcinoma (HCC)<br><br>          -  Genotype-1 hepatitis C virus (HCV) infection<br><br>          -  Plasma HCV ribonucleic acid (RNA) of more than 10,000 IU per mL<br><br>          -  Documented human immunodeficiency virus-type 1 (HIV-1) infection at least 6 months<br>             prior to screening<br><br>        Exclusion Criteria:<br><br>          -  Patient showing evidence of hepatic decompensation (ie, history or current evidence of<br>             ascites, bleeding varices or hepatic encephalopathy, albumin serum concentration less<br>             than 3.3 gm per dL, prolonged prothrombin time [PT] expressed as international<br>             normalized ratio [INR] more than 1.5)<br><br>          -  Any liver disease of non-HCV etiology<br><br>          -  Co-infection with hepatitis B virus (hepatitis B surface antigen [HBsAg] positive)<br><br>          -  An acute HIV-1 infection; or HIV-2 infection<br><br>          -  Change in antiretroviral (ARV) regimen within the last 4 weeks prior screening<br>