<br>        Inclusion Criteria:<br><br>          -  Male or female patient between 18 and 80 years of age and in good general health<br>             condition.<br><br>          -  Signed written informed consent.<br><br>          -  Existence of moderate to severe DES symptoms defined as Break-up time (TBUT) = 10 s<br>             (mean of 3 consecutive measurements) and OSDI questionnaire = 20.<br><br>        Exclusion Criteria:<br><br>          -  Contraindication for the use of the products (e.g. hypersensitivity to the<br>             constituents of the test products) or any study procedure.<br><br>          -  Concomitant or previous participation in a clinical investigation within the last 3<br>             months.<br><br>          -  Concomitant therapies/manipulations that affect either the tear film, tear secretion<br>             or ocular surface integrity or would alter the effect of the devices being evaluated.<br><br>          -  Concurrent (systemic) DES-associated diseases that are not on a stable therapy since<br>             at least 1 month (therapy not expected to change)<br><br>          -  Glaucoma that is not on a stable dosage since at least 2 weeks (therapy not expected<br>             to change)<br><br>          -  Any diseases or characteristics judged by the investigator to be incompatible with the<br>             assessments and/or procedures for the study evaluation<br><br>          -  Pregnant or lactating females.<br><br>          -  Participants of childbearing age who do not use adequate methods of birth control.<br><br>          -  Subjects unable to understand the informed consent or having a high probability of<br>             noncompliance to the study procedures and/or non-completion of the study according to<br>             investigator's judgment (e.g. illiteracy, insufficient knowledge of local language).<br><br>          -  Subjects not capable of contracting and of understanding the nature, risks,<br>             significance and implications of the clinical investigation and unable to form a<br>             rational intention in the light of these facts.<br>