GO Category,,p-value,#genes,,#miRNAs,,#genes cellular nitrogen compound metabolic process,200.1312471,7.39E-201,73,BP,73,,2894 biosynthetic process,115.263534,5.45E-116,73,BP,73,,2355 cellular protein modification process,96.04773838,8.96E-97,72,BP,72,,1451 small molecule metabolic process,78.34012871,4.57E-79,72,BP,72,,1400 gene expression,75.08200084,8.28E-76,68,BP,68,,403 neurotrophin TRK receptor signaling pathway,65.88107431,1.31E-66,69,BP,69,,206 catabolic process,61.69081269,2.04E-62,71,BP,71,,1166 viral process,57.21153783,6.14E-58,66,BP,66,,323 "symbiosis, encompassing mutualism through parasitism",55.6917717,2.03E-56,66,BP,66,,355 Fc-epsilon receptor signaling pathway,42.86056865,1.38E-43,65,BP,65,,125 organelle,59.03574037,9.21E-60,73,CC,,,5859 protein complex,49.07727454,8.37E-50,73,CC,67,,2143 cellular_component,39.60906489,2.46E-40,73,CC,71,,9241 cytosol,35.98716278,1.03E-36,72,CC,71,,1545 nucleoplasm,30.7878124,1.63E-31,71,CC,62,,694 platelet alpha granule lumen,6.335358024,4.62E-07,30,CC,70,,29 microtubule organizing center,6.335358024,4.62E-07,70,CC,67,,251 lysosomal lumen,3.465907866,0.000342052,36,CC,71,,35 vacuole,1.538552754,0.028936583,61,CC,70,,151 cell-cell junction,4,0.0001,22,CC,66,,22 ion binding,194.4293013,3.72E-195,73,MF,66,,3597 molecular_function,45.59204883,2.56E-46,73,MF,69,,9160 nucleic acid binding transcription factor activity,45.02737115,9.39E-46,72,MF,52,,627 protein binding transcription factor activity,40.6090663,2.46E-41,70,MF,65,,335 enzyme binding,39.95353901,1.11E-40,71,MF,59,,773 cytoskeletal protein binding,21.46082326,3.46E-22,69,MF,68,,452 enzyme regulator activity,14.73502786,1.84E-15,70,MF,71,,458 RNA binding,6.271023841,5.36E-07,71,MF,54,,929 transmembrane transporter activity,6.242174317,5.73E-07,70,MF,54,,539 "protein binding, bridging",1.751832017,0.017707938,64,MF,52,,83 ,,,,,56,, cellular protein metabolic process,,2.40E-43,295,,66,,295 cellular component assembly,,4.69E-41,774,,62,,774 nucleobase-containing compound catabolic process,,2.02E-37,548,,48,,548 post-translational protein modification,,8.34E-35,127,,73,,127 blood coagulation,,2.68E-34,285,,69,,285 mitotic cell cycle,,2.70E-30,238,,56,,238 macromolecular complex assembly,,2.09E-28,513,,71,,513 response to stress,,3.41E-28,1224,,53,,1224 membrane organization,,9.89E-25,343,,49,,343 epidermal growth factor receptor signaling pathway,,1.26E-24,149,,56,,149 cell death,,9.35E-23,525,,63,,525 Fc-gamma receptor signaling pathway involved in phagocytosis,,4.77E-20,56,,52,,56 platelet activation,,5.94E-20,134,,49,,134 cellular lipid metabolic process,,6.33E-20,99,,48,,99 synaptic transmission,,1.19E-17,250,,72,,250 protein complex assembly,,3.18E-17,425,,53,,425 toll-like receptor TLR1:TLR2 signaling pathway,,8.81E-17,49,,59,,49 toll-like receptor TLR6:TLR2 signaling pathway,,8.81E-17,49,,60,,49 toll-like receptor 10 signaling pathway,,5.27E-16,46,,45,,46 TRIF-dependent toll-like receptor signaling pathway,,4.34E-15,50,,57,,50 fibroblast growth factor receptor signaling pathway,,5.62E-15,127,,58,,127 mRNA metabolic process,,7.52E-15,121,,60,,121 cellular component disassembly involved in execution phase of apoptosis,,1.10E-14,37,,56,,37 biological_process,,3.09E-14,8782,,54,,8782 cell-cell signaling,,4.00E-14,363,,55,,363 MyD88-independent toll-like receptor signaling pathway,,1.28E-13,52,,38,,52 DNA metabolic process,,1.94E-13,419,,48,,419 toll-like receptor 9 signaling pathway,,2.77E-13,50,,34,,50 water-soluble vitamin metabolic process,,4.07E-13,49,,47,,49 glycosaminoglycan metabolic process,,4.40E-13,69,,60,,69 RNA metabolic process,,8.16E-13,136,,44,,136 toll-like receptor 5 signaling pathway,,1.28E-12,46,,66,,46 vitamin metabolic process,,2.47E-12,52,,32,,52 cell junction assembly,,4.78E-12,46,,64,,46 immune system process,,5.14E-12,816,,25,,816 extracellular matrix disassembly,,5.40E-12,71,,34,,71 phosphatidylinositol-mediated signaling,,8.73E-12,91,,46,,91 cell junction organization,,1.31E-11,99,,29,,99 platelet degranulation,,1.66E-11,50,,56,,50 protein N-linked glycosylation via asparagine,,3.00E-11,66,,60,,66 toll-like receptor 4 signaling pathway,,3.08E-11,63,,56,,63 toll-like receptor signaling pathway,,7.72E-11,71,,64,,71 toll-like receptor 3 signaling pathway,,1.55E-10,52,,63,,52 toll-like receptor 2 signaling pathway,,3.71E-10,50,,57,,50 energy reserve metabolic process,,7.70E-10,63,,46,,63 activation of signaling protein activity involved in unfolded protein response,,1.20E-08,41,,54,,41 glycerophospholipid biosynthetic process,,2.78E-08,53,,57,,53 O-glycan processing,,3.65E-08,36,,69,,36 stress-activated MAPK cascade,,3.99E-08,37,,36,,37 transcription initiation from RNA polymerase II promoter,,4.43E-08,127,,38,,127 inositol phosphate metabolic process,,7.69E-08,30,,71,,30 extracellular matrix organization,,8.39E-08,205,,70,,205 "nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",,8.67E-08,28,,55,,28 insulin receptor signaling pathway,,1.04E-07,103,,68,,103 nucleotide-binding oligomerization domain containing signaling pathway,,1.27E-07,19,,34,,19 nucleobase-containing small molecule metabolic process,,1.83E-07,40,,48,,40 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,,2.68E-07,43,,53,,43 hexose transport,,3.68E-07,26,,45,,26 phospholipid metabolic process,,4.02E-07,96,,38,,96 chromatin organization,,4.43E-07,76,,42,,76 G2/M transition of mitotic cell cycle,,4.48E-07,86,,29,,86 generation of precursor metabolites and energy,,7.10E-07,171,,46,,171 sulfur compound metabolic process,,7.96E-07,149,,47,,149 apoptotic signaling pathway,,8.69E-07,81,,40,,81 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,,8.81E-07,41,,42,,41 xenobiotic metabolic process,,9.70E-07,75,,72,,75 MyD88-dependent toll-like receptor signaling pathway,,1.47E-06,55,,31,,55 innate immune response,,1.57E-06,362,,34,,362 chondroitin sulfate metabolic process,,3.32E-06,30,,61,,30 termination of RNA polymerase II transcription,,5.15E-06,29,,44,,29 axon guidance,,5.98E-06,248,,26,,248 homeostatic process,,1.21E-05,407,,55,,407 anatomical structure morphogenesis,,1.54E-05,63,,73,,63 cell motility,,1.60E-05,286,,30,,286 mRNA 3'-end processing,,1.89E-05,26,,16,,26 activation of phospholipase C activity,,2.25E-05,40,,48,,40 cell-cell junction organization,,3.12E-05,50,,47,,50 phosphatidylinositol biosynthetic process,,4.68E-05,39,,55,,39 regulation of transcription from RNA polymerase II promoter in response to hypoxia,,4.98E-05,20,,60,,20 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,,6.21E-05,36,,44,,36 keratan sulfate biosynthetic process,,6.26E-05,18,,65,,18 intrinsic apoptotic signaling pathway,,8.10E-05,42,,43,,42 viral life cycle,,9.00E-05,53,,24,,53 regulation of cellular amino acid metabolic process,,0.000139278,30,,27,,30 post-Golgi vesicle-mediated transport,,0.000198874,30,,55,,30 vesicle-mediated transport,,0.000206667,514,,60,,514 keratan sulfate metabolic process,,0.000234802,19,,23,,19 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,,0.000234802,19,,68,,19 protein targeting,,0.000286016,149,,57,,149 "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",,0.000307805,35,,13,,35 JAK-STAT cascade involved in growth hormone signaling pathway,,0.000315258,17,,28,,17 cellular component movement,,0.000321327,60,,39,,60 "transcription, DNA-templated",,0.000371323,1256,,66,,1256 cellular response to glucagon stimulus,,0.000580758,24,,50,,24 long-chain fatty-acyl-CoA biosynthetic process,,0.000616557,12,,31,,12 "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",,0.000616557,40,,22,,40 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,,0.000620774,45,,22,,45 leukocyte migration,,0.000626932,59,,32,,59 protein maturation,,0.00064282,105,,58,,105 collagen catabolic process,,0.000759271,45,,17,,45 nucleocytoplasmic transport,,0.001093767,184,,31,,184 adherens junction organization,,0.001120226,28,,52,,28 regulation of defense response to virus by virus,,0.001386507,16,,28,,16 regulation of glucose transport,,0.001479854,18,,17,,18 ribonucleoprotein complex assembly,,0.001559443,77,,15,,77 G1/S transition of mitotic cell cycle,,0.001826249,95,,39,,95 activation of protein kinase A activity,,0.002514033,12,,24,,12 cytoskeleton organization,,0.002818834,327,,50,,327 regulation of small GTPase mediated signal transduction,,0.003974776,109,,20,,109 pyrimidine nucleoside catabolic process,,0.004288496,10,,29,,10 negative regulation of type I interferon production,,0.004288496,22,,31,,22 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion,,0.005417656,17,,68,,17 nervous system development,,0.005417656,230,,30,,230 antigen processing and presentation of exogenous peptide antigen via MHC class II,,0.007000182,59,,41,,59 blood circulation,,0.007760335,26,,12,,26 pyrimidine nucleobase metabolic process,,0.008259766,16,,28,,16 regulation of rhodopsin mediated signaling pathway,,0.008259766,16,,43,,16 positive regulation of muscle cell differentiation,,0.009532857,19,,34,,19 cofactor metabolic process,,0.009773762,115,,18,,115 interaction with host,,0.010302699,18,,26,,18 triglyceride biosynthetic process,,0.010389373,29,,18,,29 muscle cell differentiation,,0.010389373,29,,,,29 C-terminal protein lipidation,,0.011795873,16,,,,16 3'-phosphoadenosine 5'-phosphosulfate metabolic process,,0.012137565,11,,,,11 ncRNA metabolic process,,0.013080233,13,,,,13 nuclear-transcribed mRNA poly(A) tail shortening,,0.016053643,22,,,,22 cell communication by electrical coupling involved in cardiac conduction,,0.016249565,9,,,,9 muscle contraction,,0.019045369,62,,,,62 branched-chain amino acid catabolic process,,0.019057841,14,,,,14 glutamate secretion,,0.023428984,16,,,,16 'de novo' posttranslational protein folding,,0.023428984,21,,,,21 cell proliferation,,0.025600731,320,,,,320 mitotic nuclear envelope disassembly,,0.026334068,19,,,,19 positive regulation of type I interferon production,,0.026499029,31,,,,31 sulfur amino acid metabolic process,,0.027117504,14,,,,14 regulation of nitric-oxide synthase activity,,0.027117504,14,,,,14 transcription elongation from RNA polymerase II promoter,,0.027575436,39,,,,39 dolichol-linked oligosaccharide biosynthetic process,,0.027684368,23,,,,23 glutathione derivative biosynthetic process,,0.02870147,13,,,,13 intracellular transport of virus,,0.03586897,11,,,,11 "nucleotide-excision repair, DNA damage removal",,0.042152074,13,,,,13