struct_id name action_type EntrezGeneSymbol (NSPD) action_type_simple manual_add 927 distigmine INHIBITOR ACHE inhibitor no 2551 tacrine INHIBITOR ACHE inhibitor no 1897 neostigmine INHIBITOR ACHE inhibitor no 946 donepezil INHIBITOR ACHE inhibitor no 2231 pralidoxime ACTIVATOR ACHE activation no 988 edrophonium INHIBITOR ACHE inhibitor no 801 demecarium INHIBITOR ACHE inhibitor no 2330 pyridostigmine INHIBITOR ACHE inhibitor no 1494 fluostigmine INHIBITOR ACHE inhibitor no 2392 rivastigmine INHIBITOR ACHE inhibitor no 982 echothiophate INHIBITOR ACHE inhibitor no 2159 physostigmine INHIBITOR ACHE inhibitor no 1272 galantamine INHIBITOR ACHE inhibitor no 4908 acotiamide INHIBITOR ACHE inhibitor no 1365 hexafluronium INHIBITOR ACHE inhibitor no 146 ambenonium INHIBITOR ACHE inhibitor no 90 adenosine AGONIST ADORA1 activation no 463 caffeine ANTAGONIST ADORA1 inhibitor no 2620 theophylline ANTAGONIST ADORA1 inhibitor no 4390 choline theophyllinate ANTAGONIST ADORA1 inhibitor no 4426 bufylline ANTAGONIST ADORA1 inhibitor no 2620 theophylline ANTAGONIST ADORA2A inhibitor no 463 caffeine ANTAGONIST ADORA2A inhibitor no 2362 regadenoson AGONIST ADORA2A activation no 90 adenosine AGONIST ADORA2A activation no 4390 choline theophyllinate ANTAGONIST ADORA2A inhibitor no 4426 bufylline ANTAGONIST ADORA2A inhibitor no 4882 istradefylline ANTAGONIST ADORA2A inhibitor no 2149 phenylpropanolamine AGONIST ADRA1A activation no 1694 mephentermine AGONIST ADRA1A activation no 2032 oxymetazoline AGONIST ADRA1A activation no 1960 norepinephrine AGONIST ADRA1A activation no 1028 epinephrine AGONIST ADRA1A activation no 3591 tetryzoline AGONIST ADRA1A activation no 971 droxidopa AGONIST ADRA1A activation no 2142 phentolamine ANTAGONIST ADRA1A inhibitor no 3584 terazosin ANTAGONIST ADRA1A inhibitor no 2695 tolazoline ANTAGONIST ADRA1A inhibitor no 2146 phenylephrine AGONIST ADRA1A activation no 2136 phenoxybenzamine ANTAGONIST ADRA1A inhibitor no 1803 midodrine AGONIST ADRA1A activation no 1753 methoxamine AGONIST ADRA1A activation no 1721 metaraminol AGONIST ADRA1A activation no 954 doxazosin ANTAGONIST ADRA1A inhibitor no 781 dapiprazole ANTAGONIST ADRA1A inhibitor no 429 bunazosin ANTAGONIST ADRA1A inhibitor no 2796 urapidil ANTAGONIST ADRA1A inhibitor no 115 alfuzosin ANTAGONIST ADRA1A inhibitor no 1873 naftopidil ANTAGONIST ADRA1A inhibitor no 4151 silodosin ANTAGONIST ADRA1A inhibitor no 4209 prazosin INVERSE AGONIST ADRA1A inhibitor no 3369 naphazoline AGONIST ADRA2A activation no 1028 epinephrine AGONIST ADRA2A activation no 3952 guanabenz AGONIST ADRA2A activation no 1960 norepinephrine AGONIST ADRA2A activation no 3591 tetryzoline AGONIST ADRA2A activation no 835 dexmedetomidine AGONIST ADRA2A activation no 971 droxidopa AGONIST ADRA2A activation no 704 clonidine AGONIST ADRA2A activation no 229 apraclonidine AGONIST ADRA2A activation no 1593 lofexidine AGONIST ADRA2A activation no 2142 phentolamine ANTAGONIST ADRA2A inhibitor no 2695 tolazoline ANTAGONIST ADRA2A inhibitor no 2683 tizanidine AGONIST ADRA2A activation no 2136 phenoxybenzamine ANTAGONIST ADRA2A inhibitor no 1762 methyldopa AGONIST ADRA2A activation no 1343 guanfacine AGONIST ADRA2A activation no 922 dipivefrine AGONIST ADRA2A activation no 395 brimonidine AGONIST ADRA2A activation no 3659 yohimbine ANTAGONIST ADRA2A inhibitor no 4218 methyldopate AGONIST ADRA2A activation no 4482 corbadrine AGONIST ADRA2A activation no 3658 xylometazoline AGONIST ADRA2B activation no 3369 naphazoline AGONIST ADRA2B activation no 2136 phenoxybenzamine ANTAGONIST ADRA2B inhibitor no 229 apraclonidine AGONIST ADRA2B activation no 2032 oxymetazoline AGONIST ADRA2B activation no 835 dexmedetomidine AGONIST ADRA2B activation no 1028 epinephrine AGONIST ADRA2B activation no 3952 guanabenz AGONIST ADRA2B activation no 3591 tetryzoline AGONIST ADRA2B activation no 971 droxidopa AGONIST ADRA2B activation no 704 clonidine AGONIST ADRA2B activation no 2142 phentolamine ANTAGONIST ADRA2B inhibitor no 2695 tolazoline ANTAGONIST ADRA2B inhibitor no 2683 tizanidine AGONIST ADRA2B activation no 922 dipivefrine AGONIST ADRA2B activation no 395 brimonidine AGONIST ADRA2B activation no 3659 yohimbine ANTAGONIST ADRA2B inhibitor no 4218 methyldopate AGONIST ADRA2B activation no 4482 corbadrine AGONIST ADRA2B activation no 2695 tolazoline ANTAGONIST ADRA2C inhibitor no 2683 tizanidine AGONIST ADRA2C activation no 922 dipivefrine AGONIST ADRA2C activation no 704 clonidine AGONIST ADRA2C activation no 395 brimonidine AGONIST ADRA2C activation no 3369 naphazoline AGONIST ADRA2C activation no 1960 norepinephrine AGONIST ADRA2C activation no 835 dexmedetomidine AGONIST ADRA2C activation no 1028 epinephrine AGONIST ADRA2C activation no 3952 guanabenz AGONIST ADRA2C activation no 3591 tetryzoline AGONIST ADRA2C activation no 971 droxidopa AGONIST ADRA2C activation no 229 apraclonidine AGONIST ADRA2C activation no 2142 phentolamine ANTAGONIST ADRA2C inhibitor no 3659 yohimbine ANTAGONIST ADRA2C inhibitor no 4218 methyldopate AGONIST ADRA2C activation no 4482 corbadrine AGONIST ADRA2C activation no 1545 landiolol ANTAGONIST ADRB1 inhibitor no 237 arbutamine AGONIST ADRB1 activation no 1101 etilefrine AGONIST ADRB1 activation no 4824 etilefrine pivalate AGONIST ADRB1 activation no 13 levdobutamine AGONIST ADRB1 activation no 433 bupranolol ANTAGONIST ADRB1 inhibitor no 3486 practolol ANTAGONIST ADRB1 inhibitor no 522 carvedilol ANTAGONIST ADRB1 inhibitor no 1865 nadolol ANTAGONIST ADRB1 inhibitor no 806 denopamine AGONIST ADRB1 activation no 431 levobunolol ANTAGONIST ADRB1 inhibitor no 1531 labetalol ANTAGONIST ADRB1 inhibitor no 2291 propafenone ANTAGONIST ADRB1 inhibitor no 971 droxidopa AGONIST ADRB1 activation no 1779 metipranolol ANTAGONIST ADRB1 inhibitor no 4061 timolol ANTAGONIST ADRB1 inhibitor no 2464 sotalol ANTAGONIST ADRB1 inhibitor no 2303 propranolol ANTAGONIST ADRB1 inhibitor no 2176 pindolol PARTIAL AGONIST ADRB1 activation no 2078 penbutolol ANTAGONIST ADRB1 inhibitor no 2027 oxprenolol ANTAGONIST ADRB1 inhibitor no 1887 nebivolol ANTAGONIST ADRB1 inhibitor no 1786 metoprolol ANTAGONIST ADRB1 inhibitor no 1499 isoprenaline AGONIST ADRB1 activation no 947 dopamine AGONIST ADRB1 activation no 937 dobutamine AGONIST ADRB1 activation no 520 carteolol ANTAGONIST ADRB1 inhibitor no 380 bisoprolol ANTAGONIST ADRB1 inhibitor no 356 betaxolol ANTAGONIST ADRB1 inhibitor no 255 atenolol ANTAGONIST ADRB1 inhibitor no 40 acebutolol ANTAGONIST ADRB1 inhibitor no 569 celiprolol ANTAGONIST ADRB1 inhibitor no 389 bopindolol ANTAGONIST ADRB1 inhibitor no 360 bevantolol ANTAGONIST ADRB1 inhibitor no 1960 norepinephrine AGONIST ADRB1 activation no 137 alprenolol ANTAGONIST ADRB1 inhibitor no 4752 levobetaxolol ANTAGONIST ADRB1 inhibitor no 1054 esmolol ANTAGONIST ADRB1 inhibitor no 2368 reproterol AGONIST ADRB2 activation no 2782 tulobuterol AGONIST ADRB2 activation no 4814 olodaterol ANTAGONIST ADRB2 inhibitor no 1960 norepinephrine AGONIST ADRB2 activation no 522 carvedilol ANTAGONIST ADRB2 inhibitor no 433 bupranolol ANTAGONIST ADRB2 inhibitor no 1865 nadolol ANTAGONIST ADRB2 inhibitor no 1024 ephedrine AGONIST ADRB2 activation no 431 levobunolol ANTAGONIST ADRB2 inhibitor no 1531 labetalol ANTAGONIST ADRB2 inhibitor no 1028 epinephrine AGONIST ADRB2 activation no 1720 orciprenaline AGONIST ADRB2 activation no 971 droxidopa AGONIST ADRB2 activation no 1575 levosalbutamol AGONIST ADRB2 activation no 1491 isoetarine AGONIST ADRB2 activation no 1779 metipranolol ANTAGONIST ADRB2 inhibitor no 4799 vilanterol AGONIST ADRB2 activation no 4061 timolol ANTAGONIST ADRB2 inhibitor no 2598 terbutaline AGONIST ADRB2 activation no 2464 sotalol ANTAGONIST ADRB2 inhibitor no 2390 ritodrine AGONIST ADRB2 activation no 2303 propranolol ANTAGONIST ADRB2 inhibitor no 2199 pirbuterol AGONIST ADRB2 activation no 2176 pindolol PARTIAL AGONIST ADRB2 activation no 2078 penbutolol ANTAGONIST ADRB2 inhibitor no 2027 oxprenolol ANTAGONIST ADRB2 inhibitor no 1887 nebivolol ANTAGONIST ADRB2 inhibitor no 1499 isoprenaline AGONIST ADRB2 activation no 937 dobutamine AGONIST ADRB2 activation no 520 carteolol ANTAGONIST ADRB2 inhibitor no 105 salbutamol AGONIST ADRB2 activation no 1155 fenoterol AGONIST ADRB2 activation no 389 bopindolol ANTAGONIST ADRB2 inhibitor no 2318 protokylol AGONIST ADRB2 activation no 1239 formoterol AGONIST ADRB2 activation no 2419 salmeterol AGONIST ADRB2 activation no 137 alprenolol ANTAGONIST ADRB2 inhibitor no 2273 procaterol AGONIST ADRB2 activation no 4943 arformoterol AGONIST ADRB2 activation no 384 bitolterol AGONIST ADRB2 activation no 4183 indacaterol AGONIST ADRB2 activation no 475 candesartan cilexetil ANTAGONIST AGTR1 inhibitor no 4906 fimasartan ANTAGONIST AGTR1 inhibitor no 3839 tasosartan ANTAGONIST AGTR1 inhibitor no 1985 olmesartan medoxomil ANTAGONIST AGTR1 inhibitor no 1610 losartan ANTAGONIST AGTR1 inhibitor no 1037 eprosartan ANTAGONIST AGTR1 inhibitor no 4322 azilsartan medoxomil ANTAGONIST AGTR1 inhibitor no 1481 irbesartan ANTAGONIST AGTR1 inhibitor no 2806 valsartan ANTAGONIST AGTR1 inhibitor no 2583 telmisartan ANTAGONIST AGTR1 inhibitor no 3542 saralasin ANTAGONIST AGTR1 inhibitor no 5272 angiotensin II AGONIST AGTR1 activation no 2607 testosterone AGONIST AR activation no 2033 oxymetholone AGONIST AR activation no 1882 nandrolone phenpropionate AGONIST AR activation no 2011 oxandrolone AGONIST AR activation no 965 drostanolone propionate AGONIST AR activation no 1223 flutamide ANTAGONIST AR inhibitor no 1094 ethylestrenol AGONIST AR activation no 1933 nilutamide ANTAGONIST AR inhibitor no 766 cyproterone acetate ANTAGONIST AR inhibitor no 2477 stanozolol AGONIST AR activation no 1210 fluoxymesterone AGONIST AR activation no 3356 methyltestosterone AGONIST AR activation no 1881 nandrolone decanoate AGONIST AR activation no 367 bicalutamide ANTAGONIST AR inhibitor no 2608 testosterone undecanoate AGONIST AR activation no 1879 nandrolone AGONIST AR activation no 4146 testosterone propionate AGONIST AR activation no 4454 testosterone cypionate AGONIST AR activation no 4609 testosterone enantate AGONIST AR activation no 4628 enzalutamide ANTAGONIST AR inhibitor no 779 danazol AGONIST AR activation no 3341 mestanolone AGONIST AR activation no 5278 apalutamide INHIBITOR AR inhibitor no 5334 darolutamide INHIBITOR AR inhibitor no 732 conivaptan ANTAGONIST AVPR1A inhibitor no 4910 felypressin AGONIST AVPR1A activation no 2810 vasopressin AGONIST AVPR1A activation no 2959 lypressin AGONIST AVPR1A activation no 4186 icatibant ANTAGONIST BDKRB2 inhibitor no 642 cilnidipine BLOCKER CACNA1C inhibitor no 837 dexniguldipine BLOCKER CACNA1C inhibitor no 1631 manidipine BLOCKER CACNA1C inhibitor no 1934 nilvadipine BLOCKER CACNA1C inhibitor no 4099 levamlodipine BLOCKER CACNA1C inhibitor no 342 bepridil BLOCKER CACNA1C inhibitor no 2815 verapamil BLOCKER CACNA1C inhibitor no 1511 isradipine BLOCKER CACNA1C inhibitor no 1142 felodipine BLOCKER CACNA1C inhibitor no 897 diltiazem BLOCKER CACNA1C inhibitor no 674 clevidipine BLOCKER CACNA1C inhibitor no 183 amlodipine BLOCKER CACNA1C inhibitor no 1942 nisoldipine GATING INHIBITOR CACNA1C inhibitor no 1947 nitrendipine BLOCKER CACNA1C inhibitor no 1937 nimodipine BLOCKER CACNA1C inhibitor no 1922 nifedipine BLOCKER CACNA1C inhibitor no 234 aranidipine BLOCKER CACNA1C inhibitor no 992 efonidipine BLOCKER CACNA1C inhibitor no 5 (S)-nicardipine BLOCKER CACNA1C inhibitor no 290 barnidipine BLOCKER CACNA1C inhibitor no 272 azelnidipine BLOCKER CACNA1C inhibitor no 1909 nicardipine BLOCKER CACNA1C inhibitor no 1532 lacidipine BLOCKER CACNA1C inhibitor no 6 (S)-nitrendipine BLOCKER CACNA1C inhibitor no 3880 benidipine BLOCKER CACNA1C inhibitor no 4157 lercanidipine BLOCKER CACNA1C inhibitor no 579 ceruletide AGONIST CCKAR activation no 1736 methanthelinium ANTAGONIST CHRM1 inhibitor no 81 aclatonium AGONIST CHRM1 activation no 4302 glycopyrronium bromide ANTAGONIST CHRM1 inhibitor no 2424 scopolamine ANTAGONIST CHRM1 inhibitor no 2039 oxyphenonium ANTAGONIST CHRM1 inhibitor no 1402 hyoscyamine ANTAGONIST CHRM1 inhibitor no 1086 profenamine ANTAGONIST CHRM1 inhibitor no 763 cycrimine ANTAGONIST CHRM1 inhibitor no 584 cevimeline AGONIST CHRM1 activation no 333 benzatropine ANTAGONIST CHRM1 inhibitor no 260 atropine ANTAGONIST CHRM1 inhibitor no 2276 procyclidine ANTAGONIST CHRM1 inhibitor no 223 octatropine methylbromide ANTAGONIST CHRM1 inhibitor no 2293 propantheline ANTAGONIST CHRM1 inhibitor no 1371 hexocyclium ANTAGONIST CHRM1 inhibitor no 313 diphenidol ANTAGONIST CHRM1 inhibitor no 868 dicycloverine ANTAGONIST CHRM1 inhibitor no 915 diphemanil ANTAGONIST CHRM1 inhibitor no 2745 trihexyphenidyl ANTAGONIST CHRM1 inhibitor no 1780 metixene ANTAGONIST CHRM1 inhibitor no 1757 methscopolamine ANTAGONIST CHRM1 inhibitor no 2737 tridihexethyl ANTAGONIST CHRM1 inhibitor no 2200 pirenzepine ANTAGONIST CHRM1 inhibitor no 1689 mepenzolate ANTAGONIST CHRM1 inhibitor no 2026 oxyphencyclimine ANTAGONIST CHRM1 inhibitor no 676 clidinium ANTAGONIST CHRM1 inhibitor no 1500 isopropamide ANTAGONIST CHRM1 inhibitor no 2028 oxybutynin ANTAGONIST CHRM1 inhibitor no 374 biperiden ANTAGONIST CHRM1 inhibitor no 5303 revefenacin ANTAGONIST CHRM1 inhibitor no 1736 methanthelinium ANTAGONIST CHRM2 inhibitor no 81 aclatonium AGONIST CHRM2 activation no 4302 glycopyrronium bromide ANTAGONIST CHRM2 inhibitor no 4191 fesoterodine ANTAGONIST CHRM2 inhibitor no 1402 hyoscyamine ANTAGONIST CHRM2 inhibitor no 260 atropine ANTAGONIST CHRM2 inhibitor no 2293 propantheline ANTAGONIST CHRM2 inhibitor no 831 dexetimide ANTAGONIST CHRM2 inhibitor no 358 bethanechol AGONIST CHRM2 activation no 1273 gallamine NEGATIVE ALLOSTERIC MODULATOR CHRM2 inhibitor no 2705 tolterodine ANTAGONIST CHRM2 inhibitor no 2457 solifenacin ANTAGONIST CHRM2 inhibitor no 2776 trospium ANTAGONIST CHRM2 inhibitor no 5303 revefenacin ANTAGONIST CHRM2 inhibitor no 1736 methanthelinium ANTAGONIST CHRM3 inhibitor no 81 aclatonium AGONIST CHRM3 activation no 2166 pilocarpine AGONIST CHRM3 activation no 4302 glycopyrronium bromide ANTAGONIST CHRM3 inhibitor no 4816 umeclidinium ANTAGONIST CHRM3 inhibitor no 4191 fesoterodine ANTAGONIST CHRM3 inhibitor no 2776 trospium ANTAGONIST CHRM3 inhibitor no 2677 tiotropium bromide ANTAGONIST CHRM3 inhibitor no 1475 ipratropium ANTAGONIST CHRM3 inhibitor no 1402 hyoscyamine ANTAGONIST CHRM3 inhibitor no 584 cevimeline AGONIST CHRM3 activation no 488 carbachol AGONIST CHRM3 activation no 260 atropine ANTAGONIST CHRM3 inhibitor no 65 acetylcholine AGONIST CHRM3 activation no 1726 methacholine AGONIST CHRM3 activation no 915 diphemanil ANTAGONIST CHRM3 inhibitor no 223 octatropine methylbromide ANTAGONIST CHRM3 inhibitor no 2293 propantheline ANTAGONIST CHRM3 inhibitor no 676 clidinium ANTAGONIST CHRM3 inhibitor no 1371 hexocyclium ANTAGONIST CHRM3 inhibitor no 358 bethanechol AGONIST CHRM3 activation no 868 dicycloverine ANTAGONIST CHRM3 inhibitor no 2774 tropicamide ANTAGONIST CHRM3 inhibitor no 757 cyclopentolate ANTAGONIST CHRM3 inhibitor no 2737 tridihexethyl ANTAGONIST CHRM3 inhibitor no 2705 tolterodine ANTAGONIST CHRM3 inhibitor no 1689 mepenzolate ANTAGONIST CHRM3 inhibitor no 2026 oxyphencyclimine ANTAGONIST CHRM3 inhibitor no 2039 oxyphenonium ANTAGONIST CHRM3 inhibitor no 1500 isopropamide ANTAGONIST CHRM3 inhibitor no 2028 oxybutynin ANTAGONIST CHRM3 inhibitor no 2457 solifenacin ANTAGONIST CHRM3 inhibitor no 4902 imidafenacin ANTAGONIST CHRM3 inhibitor no 784 darifenacin ANTAGONIST CHRM3 inhibitor no 1757 methscopolamine ANTAGONIST CHRM3 inhibitor no 4484 aclidinium bromide ANTAGONIST CHRM3 inhibitor no 5303 revefenacin ANTAGONIST CHRM3 inhibitor no 1736 methanthelinium ANTAGONIST CHRM4 inhibitor no 81 aclatonium AGONIST CHRM4 activation no 4302 glycopyrronium bromide ANTAGONIST CHRM4 inhibitor no 5303 revefenacin ANTAGONIST CHRM4 inhibitor no 1736 methanthelinium ANTAGONIST CHRM5 inhibitor no 81 aclatonium AGONIST CHRM5 activation no 4302 glycopyrronium bromide ANTAGONIST CHRM5 inhibitor no 5303 revefenacin ANTAGONIST CHRM5 inhibitor no 2808 varenicline AGONIST CHRNA4 activation no 1920 nicotine AGONIST CHRNA4 activation no 4109 dronabinol AGONIST CNR1 activation no 52 paracetamol AGONIST CNR1 activation no 1862 nabilone AGONIST CNR1 activation no 4150 rimonabant ANTAGONIST CNR1 inhibitor no 2105 pergolide AGONIST DRD1 activation no 1211 flupentixol ANTAGONIST DRD1 inhibitor no 1764 methylergometrine ANTAGONIST DRD1 inhibitor no 1153 fenoldopam AGONIST DRD1 activation no 2877 zuclopenthixol ANTAGONIST DRD1 inhibitor no 1567 levodopa AGONIST DRD1 activation no 2407 rotigotine AGONIST DRD2 activation no 5052 aripiprazole lauroxil PARTIAL AGONIST DRD2 activation no 4496 haloperidol decanoate INVERSE AGONIST DRD2 inhibitor no 5014 brexpiprazole AGONIST DRD2 activation no 4168 lurasidone ANTAGONIST DRD2 inhibitor no 4137 paliperidone ANTAGONIST DRD2 inhibitor no 2742 triflupromazine ANTAGONIST DRD2 inhibitor no 2740 trifluoperazine ANTAGONIST DRD2 inhibitor no 2639 thiothixene ANTAGONIST DRD2 inhibitor no 2193 pipotiazine palmitate ANTAGONIST DRD2 inhibitor no 1712 mesoridazine ANTAGONIST DRD2 inhibitor no 1214 fluphenazine enanthate ANTAGONIST DRD2 inhibitor no 966 droperidol ANTAGONIST DRD2 inhibitor no 516 carfenazine ANTAGONIST DRD2 inhibitor no 59 acetophenazine ANTAGONIST DRD2 inhibitor no 460 cabergoline AGONIST DRD2 activation no 945 domperidone ANTAGONIST DRD2 inhibitor no 1211 flupentixol ANTAGONIST DRD2 inhibitor no 2202 piribedil AGONIST DRD2 activation no 228 apomorphine AGONIST DRD2 activation no 623 chlorprothixene ANTAGONIST DRD2 inhibitor no 4115 asenapine ANTAGONIST DRD2 inhibitor no 3294 iloperidone ANTAGONIST DRD2 inhibitor no 2865 ziprasidone ANTAGONIST DRD2 inhibitor no 2637 thioridazine ANTAGONIST DRD2 inhibitor no 2630 thiethylperazine ANTAGONIST DRD2 inhibitor no 2389 risperidone ANTAGONIST DRD2 inhibitor no 2337 quetiapine ANTAGONIST DRD2 inhibitor no 2284 promazine ANTAGONIST DRD2 inhibitor no 2274 prochlorperazine ANTAGONIST DRD2 inhibitor no 2233 pramipexole AGONIST DRD2 activation no 2172 pimozide ANTAGONIST DRD2 inhibitor no 2113 perphenazine ANTAGONIST DRD2 inhibitor no 2105 pergolide AGONIST DRD2 activation no 1982 olanzapine ANTAGONIST DRD2 inhibitor no 1830 molindone ANTAGONIST DRD2 inhibitor no 1782 metoclopramide ANTAGONIST DRD2 inhibitor no 1353 haloperidol INVERSE AGONIST DRD2 inhibitor no 1212 fluphenazine ANTAGONIST DRD2 inhibitor no 722 clozapine ANTAGONIST DRD2 inhibitor no 621 chlorpromazine ANTAGONIST DRD2 inhibitor no 403 bromocriptine AGONIST DRD2 activation no 242 aripiprazole PARTIAL AGONIST DRD2 activation no 2877 zuclopenthixol ANTAGONIST DRD2 inhibitor no 1567 levodopa AGONIST DRD2 activation no 407 bromperidol ANTAGONIST DRD2 inhibitor no 179 amisulpride ANTAGONIST DRD2 inhibitor no 1613 loxapine ANTAGONIST DRD2 inhibitor no 2537 sulpiride ANTAGONIST DRD2 inhibitor no 2365 remoxipride ANTAGONIST DRD2 inhibitor no 2470 spiperone ANTAGONIST DRD2 inhibitor no 4498 paliperidone palmitate ANTAGONIST DRD2 inhibitor no 331 benzquinamide AGONIST DRD2 activation no 388 blonanserin ANTAGONIST DRD2 inhibitor no 2112 perospirone ANTAGONIST DRD2 inhibitor no 2435 sertindole ANTAGONIST DRD2 inhibitor no 1213 fluphenazine decanoate ANTAGONIST DRD2 inhibitor no 5037 cariprazine PARTIAL AGONIST DRD2 activation no 2402 ropinirole AGONIST DRD2 activation no 5358 lumateperone ANTAGONIST DRD2 inhibitor no 4809 macitentan ANTAGONIST EDNRA inhibitor no 4337 ambrisentan ANTAGONIST EDNRA inhibitor no 3548 sitaxentan ANTAGONIST EDNRA inhibitor no 392 bosentan ANTAGONIST EDNRA inhibitor no 4809 macitentan ANTAGONIST EDNRB inhibitor no 392 bosentan ANTAGONIST EDNRB inhibitor no 1754 methoxyflurane POSITIVE MODULATOR GABRA1 activation no 811 desflurane POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2302 propofol POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1493 isoflurane POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1356 halothane POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1740 metharbital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2439 sevoflurane POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2556 talbutal POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2735 triclofos POSITIVE MODULATOR GABRA1 activation no 2626 thiamylal POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 852 diazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2873 zopiclone POSITIVE MODULATOR GABRA1 activation no 2870 zolpidem POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2857 zaleplon POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2729 triazolam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2706 topiramate POSITIVE MODULATOR GABRA1 activation no 2633 thiopental POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2585 temazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2428 secobarbital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2267 primidone POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2240 prazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2095 pentobarbital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2015 oxazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1945 nitrazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1802 midazolam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1774 methyprylon POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1748 methohexital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1704 meprobamate AGONIST GABRA1 activation no 1606 lorazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1313 glutethimide POSITIVE MODULATOR GABRA1 activation no 1218 flurazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1195 flumazenil ALLOSTERIC ANTAGONIST GABRA1 inhibitor no 1109 etomidate POSITIVE MODULATOR GABRA1 activation no 1078 ethchlorvynol POSITIVE MODULATOR GABRA1 activation no 1068 eszopiclone POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1056 estazolam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 711 clorazepate POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 703 clonazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 682 clobazam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 594 chlordiazepoxide POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 441 butalbital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 439 secbutabarbital POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 136 alprazolam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 38 acamprosate POSITIVE MODULATOR GABRA1 activation no 2336 quazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 1348 halazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 3249 fospropofol POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 93 adinazolam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation no 2870 zolpidem ALLOSTERIC MODULATOR GABRA1 activation no 1202 flunitrazepam ALLOSTERIC MODULATOR GABRA1 activation no 5271 macimorelin AGONIST GHSR activation no 2232 pralmorelin AGONIST GHSR activation no 1679 memantine NEGATIVE ALLOSTERIC MODULATOR GRIN1 inhibitor no 38 acamprosate ANTAGONIST GRIN1 inhibitor no 1523 ketamine BLOCKER GRIN1 inhibitor no 144 amantadine BLOCKER GRIN1 inhibitor no 4976 triamcinolone hexacetonide AGONIST NR3C1 activation no 1770 methylprednisolone acetate AGONIST NR3C1 activation no 4647 fluorometholone acetate AGONIST NR3C1 activation no 2726 triamcinolone acetonide AGONIST NR3C1 activation no 2253 prednisone AGONIST NR3C1 activation no 2245 prednisolone AGONIST NR3C1 activation no 1805 mifepristone ANTAGONIST NR3C1 inhibitor no 1768 methylprednisolone AGONIST NR3C1 activation no 1388 hydrocortisone AGONIST NR3C1 activation no 1225 fluticasone propionate AGONIST NR3C1 activation no 1201 flunisolide AGONIST NR3C1 activation no 824 dexamethasone AGONIST NR3C1 activation no 734 cortisone acetate AGONIST NR3C1 activation no 633 ciclesonide AGONIST NR3C1 activation no 419 budesonide AGONIST NR3C1 activation no 348 betamethasone AGONIST NR3C1 activation no 1832 mometasone furoate AGONIST NR3C1 activation no 1611 loteprednol etabonate AGONIST NR3C1 activation no 1198 flumetasone pivalate AGONIST NR3C1 activation no 294 beclometasone dipropionate AGONIST NR3C1 activation no 819 desoximetasone AGONIST NR3C1 activation no 1204 fluocinolone acetonide AGONIST NR3C1 activation no 1205 fluocinonide AGONIST NR3C1 activation no 1208 fluorometholone AGONIST NR3C1 activation no 1217 fludroxycortide AGONIST NR3C1 activation no 2725 triamcinolone AGONIST NR3C1 activation no 4452 clobetasol propionate AGONIST NR3C1 activation no 4485 diflorasone diacetate AGONIST NR3C1 activation no 4507 halcinonide AGONIST NR3C1 activation no 4667 betamethasone phosphate AGONIST NR3C1 activation no 1662 medrysone AGONIST NR3C1 activation no 2384 rimexolone AGONIST NR3C1 activation no 1702 meprednisone AGONIST NR3C1 activation no 1216 fluprednisolone AGONIST NR3C1 activation no 2247 prednisolone acetate AGONIST NR3C1 activation no 4451 prednisolone sodium phosphate AGONIST NR3C1 activation no 3135 desonide AGONIST NR3C1 activation no 3959 hydrocortisone butyrate AGONIST NR3C1 activation no 826 dexamethasone acetate AGONIST NR3C1 activation no 349 betamethasone acetate AGONIST NR3C1 activation no 2251 prednisolone tebutate AGONIST NR3C1 activation no 3920 dexamethasone phosphate AGONIST NR3C1 activation no 1771 methylprednisolone succinate AGONIST NR3C1 activation no 1387 hydrocortamate AGONIST NR3C1 activation no 354 betamethasone valerate AGONIST NR3C1 activation no 2727 triamcinolone diacetate AGONIST NR3C1 activation no 1349 ulobetasol propionate AGONIST NR3C1 activation no 1390 hydrocortisone cypionate AGONIST NR3C1 activation no 2243 prednicarbate AGONIST NR3C1 activation no 351 betamethasone benzoate AGONIST NR3C1 activation no 150 amcinonide AGONIST NR3C1 activation no 353 betamethasone dipropionate AGONIST NR3C1 activation no 3142 difluprednate AGONIST NR3C1 activation no 4213 hydrocortisone acetate AGONIST NR3C1 activation no 4456 hydrocortisone succinate AGONIST NR3C1 activation no 4493 alclometasone dipropionate AGONIST NR3C1 activation no 4504 hydrocortisone valerate AGONIST NR3C1 activation no 4554 fluticasone furoate AGONIST NR3C1 activation no 4569 hydrocortisone probutate AGONIST NR3C1 activation no 4606 clocortolone pivalate AGONIST NR3C1 activation no 736 cortivazol AGONIST NR3C1 activation no 1354 halopredone acetate AGONIST NR3C1 activation no 3911 clobetasone butyrate AGONIST NR3C1 activation no 4353 bilastine ANTAGONIST HRH1 inhibitor no 2437 setastine ANTAGONIST HRH1 inhibitor no 3579 talastine ANTAGONIST HRH1 inhibitor no 1852 moxastine ANTAGONIST HRH1 inhibitor no 999 emedastine ANTAGONIST HRH1 inhibitor no 2298 propiomazine ANTAGONIST HRH1 inhibitor no 2286 promethazine ANTAGONIST HRH1 inhibitor no 1999 orphenadrine ANTAGONIST HRH1 inhibitor no 1986 olopatadine ANTAGONIST HRH1 inhibitor no 1605 loratadine ANTAGONIST HRH1 inhibitor no 1566 levocetirizine ANTAGONIST HRH1 inhibitor no 1564 levocabastine ANTAGONIST HRH1 inhibitor no 1530 ketotifen ANTAGONIST HRH1 inhibitor no 1400 hydroxyzine ANTAGONIST HRH1 inhibitor no 1170 fexofenadine ANTAGONIST HRH1 inhibitor no 1027 epinastine ANTAGONIST HRH1 inhibitor no 956 doxepin ANTAGONIST HRH1 inhibitor no 920 diphenylpyraline ANTAGONIST HRH1 inhibitor no 916 diphenhydramine ANTAGONIST HRH1 inhibitor no 814 desloratadine ANTAGONIST HRH1 inhibitor no 765 cyproheptadine ANTAGONIST HRH1 inhibitor no 671 clemastine ANTAGONIST HRH1 inhibitor no 616 chlorphenamine ANTAGONIST HRH1 inhibitor no 581 cetirizine ANTAGONIST HRH1 inhibitor no 404 bromazine ANTAGONIST HRH1 inhibitor no 271 azelastine ANTAGONIST HRH1 inhibitor no 82 acrivastine ANTAGONIST HRH1 inhibitor no 1375 histamine AGONIST HRH1 activation no 408 brompheniramine ANTAGONIST HRH1 inhibitor no 830 dexbrompheniramine ANTAGONIST HRH1 inhibitor no 341 bepotastine ANTAGONIST HRH1 inhibitor no 268 azatadine ANTAGONIST HRH1 inhibitor no 749 cyclizine ANTAGONIST HRH1 inhibitor no 901 dimenhydrinate ANTAGONIST HRH1 inhibitor no 2132 pheniramine ANTAGONIST HRH1 inhibitor no 2762 tripelennamine ANTAGONIST HRH1 inhibitor no 224 antazoline ANTAGONIST HRH1 inhibitor no 962 doxylamine ANTAGONIST HRH1 inhibitor no 2763 triprolidine ANTAGONIST HRH1 inhibitor no 2331 mepyramine ANTAGONIST HRH1 inhibitor no 499 carbinoxamine ANTAGONIST HRH1 inhibitor no 1742 methdilazine ANTAGONIST HRH1 inhibitor no 2749 alimemazine ANTAGONIST HRH1 inhibitor no 2600 terfenadine ANTAGONIST HRH1 inhibitor no 2014 oxatomide ANTAGONIST HRH1 inhibitor no 1824 mizolastine ANTAGONIST HRH1 inhibitor no 1643 mebhydrolin ANTAGONIST HRH1 inhibitor no 977 ebastine ANTAGONIST HRH1 inhibitor no 249 astemizole ANTAGONIST HRH1 inhibitor no 1649 meclozine ANTAGONIST HRH1 inhibitor no 2413 rupatadine ANTAGONIST HRH1 inhibitor no 4411 dexchlorpheniramine ANTAGONIST HRH1 inhibitor no 50 aceprometazine ANTAGONIST HRH1 inhibitor no 416 buclizine ANTAGONIST HRH1 inhibitor no 4165 alcaftadine ANTAGONIST HRH1 inhibitor no 2150 phenyltoloxamine ANTAGONIST HRH1 inhibitor no 383 bisulepine ANTAGONIST HRH1 inhibitor no 288 bamipine ANTAGONIST HRH1 inhibitor no 4002 niperotidine ANTAGONIST HRH2 inhibitor no 2358 ranitidine ANTAGONIST HRH2 inhibitor no 1955 nizatidine ANTAGONIST HRH2 inhibitor no 1129 famotidine ANTAGONIST HRH2 inhibitor no 645 cimetidine ANTAGONIST HRH2 inhibitor no 357 betazole AGONIST HRH2 activation no 2408 roxatidine acetate ANTAGONIST HRH2 inhibitor no 979 ebrotidine ANTAGONIST HRH2 inhibitor no 5052 aripiprazole lauroxil PARTIAL AGONIST HTR1A activation no 5022 flibanserin AGONIST HTR1A activation no 5014 brexpiprazole AGONIST HTR1A activation no 4806 vortioxetine AGONIST HTR1A activation no 437 buspirone PARTIAL AGONIST HTR1A activation no 242 aripiprazole PARTIAL AGONIST HTR1A activation no 4223 vilazodone AGONIST HTR1A activation no 5037 cariprazine PARTIAL AGONIST HTR1A activation no 5142 pimavanserin INVERSE AGONIST HTR2A inhibitor no 5052 aripiprazole lauroxil ANTAGONIST HTR2A inhibitor no 5022 flibanserin ANTAGONIST HTR2A inhibitor no 5014 brexpiprazole ANTAGONIST HTR2A inhibitor no 4168 lurasidone ANTAGONIST HTR2A inhibitor no 4137 paliperidone ANTAGONIST HTR2A inhibitor no 1712 mesoridazine ANTAGONIST HTR2A inhibitor no 1830 molindone ANTAGONIST HTR2A inhibitor no 2601 terguride AGONIST HTR2A activation no 966 droperidol ANTAGONIST HTR2A inhibitor no 1816 mirtazapine ANTAGONIST HTR2A inhibitor no 4115 asenapine ANTAGONIST HTR2A inhibitor no 3294 iloperidone ANTAGONIST HTR2A inhibitor no 2865 ziprasidone ANTAGONIST HTR2A inhibitor no 2717 trazodone ANTAGONIST HTR2A inhibitor no 2389 risperidone ANTAGONIST HTR2A inhibitor no 2337 quetiapine ANTAGONIST HTR2A inhibitor no 2284 promazine ANTAGONIST HTR2A inhibitor no 1982 olanzapine ANTAGONIST HTR2A inhibitor no 1890 nefazodone ANTAGONIST HTR2A inhibitor no 751 cyclobenzaprine ANTAGONIST HTR2A inhibitor no 722 clozapine ANTAGONIST HTR2A inhibitor no 242 aripiprazole ANTAGONIST HTR2A inhibitor no 1796 mianserin ANTAGONIST HTR2A inhibitor no 1613 loxapine ANTAGONIST HTR2A inhibitor no 2470 spiperone ANTAGONIST HTR2A inhibitor no 4498 paliperidone palmitate ANTAGONIST HTR2A inhibitor no 516 carfenazine ANTAGONIST HTR2A inhibitor no 388 blonanserin ANTAGONIST HTR2A inhibitor no 2435 sertindole ANTAGONIST HTR2A inhibitor no 5037 cariprazine ANTAGONIST HTR2A inhibitor no 5358 lumateperone ANTAGONIST HTR2A inhibitor no 2601 terguride ANTAGONIST HTR2B inhibitor no 1588 lisuride ANTAGONIST HTR2B inhibitor no 1796 mianserin ANTAGONIST HTR2B inhibitor no 1775 methysergide AGONIST HTR2B activation no 4374 lorcaserin AGONIST HTR2C activation no 99 agomelatine ANTAGONIST HTR2C inhibitor no 1816 mirtazapine ANTAGONIST HTR2C inhibitor no 1780 metixene ANTAGONIST HTR2C inhibitor no 2717 trazodone ANTAGONIST HTR2C inhibitor no 1796 mianserin ANTAGONIST HTR2C inhibitor no 1775 methysergide AGONIST HTR2C activation no 2435 sertindole INVERSE AGONIST HTR2C inhibitor no 4806 vortioxetine ANTAGONIST HTR3A inhibitor no 1992 ondansetron ANTAGONIST HTR3A inhibitor no 1782 metoclopramide ANTAGONIST HTR3A inhibitor no 1329 granisetron ANTAGONIST HTR3A inhibitor no 2357 ramosetron ANTAGONIST HTR3A inhibitor no 129 alosetron ANTAGONIST HTR3A inhibitor no 2046 palonosetron ANTAGONIST HTR3A inhibitor no 2775 tropisetron ANTAGONIST HTR3A inhibitor no 1438 indisetron ANTAGONIST HTR3A inhibitor no 267 azasetron ANTAGONIST HTR3A inhibitor no 3931 dolasetron ANTAGONIST HTR3A inhibitor no 4806 vortioxetine ANTAGONIST HTR7 inhibitor no 1344 guanidine BLOCKER KCNH2 inhibitor no 2464 sotalol BLOCKER KCNH2 inhibitor no 176 amiodarone BLOCKER KCNH2 inhibitor no 942 dofetilide BLOCKER KCNH2 inhibitor no 4163 fampridine BLOCKER KCNH2 inhibitor no 4336 amifampridine BLOCKER KCNH2 inhibitor no 2131 pheniprazine INHIBITOR MAOA inhibitor no 4865 mebanazine INHIBITOR MAOA inhibitor no 2206 pirlindole INHIBITOR MAOA inhibitor no 2065 pargyline INHIBITOR MAOA inhibitor no 1490 isocarboxazid INHIBITOR MAOA inhibitor no 2123 phenelzine INHIBITOR MAOA inhibitor no 1480 iproniazid INHIBITOR MAOA inhibitor no 2702 toloxatone INHIBITOR MAOA inhibitor no 1825 moclobemide INHIBITOR MAOA inhibitor no 5001 eluxadoline ANTAGONIST OPRD1 inhibitor no 1874 nalbuphine AGONIST OPRD1 activation no 1765 naltrexone ANTAGONIST OPRD1 inhibitor no 2034 oxymorphone AGONIST OPRD1 activation no 1876 nalmefene ANTAGONIST OPRD1 inhibitor no 2034 oxymorphone AGONIST OPRK1 activation no 1874 nalbuphine AGONIST OPRK1 activation no 1765 naltrexone ANTAGONIST OPRK1 inhibitor no 847 dezocine ANTAGONIST OPRK1 inhibitor no 434 buprenorphine ANTAGONIST OPRK1 inhibitor no 454 butorphanol PARTIAL AGONIST OPRK1 activation no 1876 nalmefene ANTAGONIST OPRK1 inhibitor no 4673 nalfurafine AGONIST OPRK1 activation no 5001 eluxadoline AGONIST OPRM1 activation no 4283 tapentadol AGONIST OPRM1 activation no 2029 oxycodone AGONIST OPRM1 activation no 1878 naloxone ANTAGONIST OPRM1 inhibitor no 1874 nalbuphine AGONIST OPRM1 activation no 1845 morphine AGONIST OPRM1 activation no 847 dezocine PARTIAL AGONIST OPRM1 activation no 1690 pethidine AGONIST OPRM1 activation no 1574 levorphanol AGONIST OPRM1 activation no 2711 tramadol AGONIST OPRM1 activation no 1560 levallorphan ANTAGONIST OPRM1 inhibitor no 1393 hydromorphone AGONIST OPRM1 activation no 1386 hydrocodone AGONIST OPRM1 activation no 725 codeine AGONIST OPRM1 activation no 886 dihydrocodeine AGONIST OPRM1 activation no 4616 methylnaltrexone ANTAGONIST OPRM1 inhibitor no 2491 sufentanil AGONIST OPRM1 activation no 2363 remifentanil AGONIST OPRM1 activation no 2034 oxymorphone AGONIST OPRM1 activation no 1765 naltrexone ANTAGONIST OPRM1 inhibitor no 1728 methadone AGONIST OPRM1 activation no 1599 loperamide AGONIST OPRM1 activation no 1571 levomethadyl acetate AGONIST OPRM1 activation no 1164 fentanyl AGONIST OPRM1 activation no 918 diphenoxylate AGONIST OPRM1 activation no 844 dextropropoxyphene AGONIST OPRM1 activation no 434 buprenorphine PARTIAL AGONIST OPRM1 activation no 220 anileridine AGONIST OPRM1 activation no 143 alvimopan ANTAGONIST OPRM1 inhibitor no 114 alfentanil AGONIST OPRM1 activation no 2663 tilidine AGONIST OPRM1 activation no 2299 propiram AGONIST OPRM1 activation no 1706 meptazinol PARTIAL AGONIST OPRM1 activation no 454 butorphanol PARTIAL AGONIST OPRM1 activation no 1876 nalmefene ANTAGONIST OPRM1 inhibitor no 4832 naloxegol ANTAGONIST OPRM1 inhibitor no 878 difenoxin AGONIST OPRM1 activation no 3713 ciramadol MODULATOR OPRM1 activation no 1729 acetylmethadol AGONIST OPRM1 activation no 5220 naldemedine ANTAGONIST OPRM1 inhibitor no 1987 olprinone INHIBITOR PDE3A inhibitor no 2620 theophylline INHIBITOR PDE3A inhibitor no 644 cilostazol INHIBITOR PDE3A inhibitor no 201 amrinone INHIBITOR PDE3A inhibitor no 209 anagrelide INHIBITOR PDE3A inhibitor no 1809 milrinone INHIBITOR PDE3A inhibitor no 976 diprophylline INHIBITOR PDE3A inhibitor no 924 dipyridamole INHIBITOR PDE3A inhibitor no 4390 choline theophyllinate INHIBITOR PDE3A inhibitor no 4426 bufylline INHIBITOR PDE3A inhibitor no 2171 pimobendan INHIBITOR PDE3A inhibitor no 5201 crisaborole INHIBITOR PDE4D inhibitor no 4829 apremilast INHIBITOR PDE4D inhibitor no 182 amlexanox INHIBITOR PDE4D inhibitor no 1175 flavoxate INHIBITOR PDE4D inhibitor no 3531 roflumilast INHIBITOR PDE4D inhibitor no 4390 choline theophyllinate INHIBITOR PDE4D inhibitor no 4426 bufylline INHIBITOR PDE4D inhibitor no 5047 saroglitazar AGONIST PPARG activation no 2767 troglitazone AGONIST PPARG activation no 2405 rosiglitazone AGONIST PPARG activation no 2179 pioglitazone AGONIST PPARG activation no 1988 olsalazine AGONIST PPARG activation no 284 balsalazide AGONIST PPARG activation no 1710 mesalazine AGONIST PPARG activation no 5078 lobeglitazone AGONIST PPARG activation no 2165 piketoprofen INHIBITOR PTGS1 inhibitor no 2050 aminosalicylic acid INHIBITOR PTGS1 inhibitor no 1141 felbinac INHIBITOR PTGS1 inhibitor no 2013 oxaprozin INHIBITOR PTGS1 inhibitor no 1615 loxoprofen INHIBITOR PTGS1 inhibitor no 833 dexketoprofen INHIBITOR PTGS1 inhibitor no 1988 olsalazine INHIBITOR PTGS1 inhibitor no 2145 phenylbutazone INHIBITOR PTGS1 inhibitor no 2036 oxyphenbutazone INHIBITOR PTGS1 inhibitor no 2699 tolmetin INHIBITOR PTGS1 inhibitor no 2546 suprofen INHIBITOR PTGS1 inhibitor no 2210 piroxicam INHIBITOR PTGS1 inhibitor no 1883 naproxen INHIBITOR PTGS1 inhibitor no 1710 mesalazine INHIBITOR PTGS1 inhibitor no 1663 mefenamic acid INHIBITOR PTGS1 inhibitor no 1650 meclofenamic acid INHIBITOR PTGS1 inhibitor no 1529 ketorolac INHIBITOR PTGS1 inhibitor no 1528 ketoprofen INHIBITOR PTGS1 inhibitor no 1440 indomethacin INHIBITOR PTGS1 inhibitor no 1407 ibuprofen INHIBITOR PTGS1 inhibitor no 1219 flurbiprofen INHIBITOR PTGS1 inhibitor no 1154 fenoprofen INHIBITOR PTGS1 inhibitor no 880 diflunisal INHIBITOR PTGS1 inhibitor no 865 diclofenac INHIBITOR PTGS1 inhibitor no 401 bromfenac INHIBITOR PTGS1 inhibitor no 284 balsalazide INHIBITOR PTGS1 inhibitor no 1899 nepafenac INHIBITOR PTGS1 inhibitor no 74 acetylsalicylic acid INHIBITOR PTGS1 inhibitor no 2652 tiaprofenic acid INHIBITOR PTGS1 inhibitor no 1193 flufenamic acid INHIBITOR PTGS1 inhibitor no 1145 fenbufen INHIBITOR PTGS1 inhibitor no 2525 sulfasalazine INHIBITOR PTGS1 inhibitor no 4257 bismuth subsalicylate INHIBITOR PTGS1 inhibitor no 47 acemetacin INHIBITOR PTGS1 inhibitor no 1178 floctafenine INHIBITOR PTGS1 inhibitor no 2165 piketoprofen INHIBITOR PTGS2 inhibitor no 2063 parecoxib INHIBITOR PTGS2 inhibitor no 43 aceclofenac INHIBITOR PTGS2 inhibitor no 2050 aminosalicylic acid INHIBITOR PTGS2 inhibitor no 1710 mesalazine INHIBITOR PTGS2 inhibitor no 1863 nabumetone INHIBITOR PTGS2 inhibitor no 1883 naproxen INHIBITOR PTGS2 inhibitor no 1615 loxoprofen INHIBITOR PTGS2 inhibitor no 833 dexketoprofen INHIBITOR PTGS2 inhibitor no 568 celecoxib INHIBITOR PTGS2 inhibitor no 518 carprofen INHIBITOR PTGS2 inhibitor no 1103 etodolac INHIBITOR PTGS2 inhibitor no 401 bromfenac INHIBITOR PTGS2 inhibitor no 284 balsalazide INHIBITOR PTGS2 inhibitor no 1618 lumiracoxib INHIBITOR PTGS2 inhibitor no 1899 nepafenac INHIBITOR PTGS2 inhibitor no 74 acetylsalicylic acid INHIBITOR PTGS2 inhibitor no 1988 olsalazine INHIBITOR PTGS2 inhibitor no 52 paracetamol INHIBITOR PTGS2 inhibitor no 2036 oxyphenbutazone INHIBITOR PTGS2 inhibitor no 2799 valdecoxib INHIBITOR PTGS2 inhibitor no 2699 tolmetin INHIBITOR PTGS2 inhibitor no 2546 suprofen INHIBITOR PTGS2 inhibitor no 2534 sulindac INHIBITOR PTGS2 inhibitor no 2397 rofecoxib INHIBITOR PTGS2 inhibitor no 2210 piroxicam INHIBITOR PTGS2 inhibitor no 2013 oxaprozin INHIBITOR PTGS2 inhibitor no 1663 mefenamic acid INHIBITOR PTGS2 inhibitor no 1650 meclofenamic acid INHIBITOR PTGS2 inhibitor no 1529 ketorolac INHIBITOR PTGS2 inhibitor no 1528 ketoprofen INHIBITOR PTGS2 inhibitor no 1440 indomethacin INHIBITOR PTGS2 inhibitor no 1407 ibuprofen INHIBITOR PTGS2 inhibitor no 1219 flurbiprofen INHIBITOR PTGS2 inhibitor no 1154 fenoprofen INHIBITOR PTGS2 inhibitor no 1113 etoricoxib INHIBITOR PTGS2 inhibitor no 880 diflunisal INHIBITOR PTGS2 inhibitor no 865 diclofenac INHIBITOR PTGS2 inhibitor no 2652 tiaprofenic acid INHIBITOR PTGS2 inhibitor no 1193 flufenamic acid INHIBITOR PTGS2 inhibitor no 1145 fenbufen INHIBITOR PTGS2 inhibitor no 1676 meloxicam INHIBITOR PTGS2 inhibitor no 2525 sulfasalazine INHIBITOR PTGS2 inhibitor no 4257 bismuth subsalicylate INHIBITOR PTGS2 inhibitor no 47 acemetacin INHIBITOR PTGS2 inhibitor no 1141 felbinac INHIBITOR PTGS2 inhibitor no 1178 floctafenine INHIBITOR PTGS2 inhibitor no 5240 polmacoxib INHIBITOR PTGS2 inhibitor no 5250 imrecoxib INHIBITOR PTGS2 inhibitor no 323 benzocaine BLOCKER SCN5A inhibitor no 1434 indecainide BLOCKER SCN5A inhibitor no 1247 fosphenytoin BLOCKER SCN5A inhibitor no 859 cinchocaine BLOCKER SCN5A inhibitor no 1579 lidocaine BLOCKER SCN5A inhibitor no 1088 ethotoin BLOCKER SCN5A inhibitor no 2120 phenazopyridine BLOCKER SCN5A inhibitor no 1695 mephenytoin BLOCKER SCN5A inhibitor no 3534 rufinamide BLOCKER SCN5A inhibitor no 1540 lamotrigine BLOCKER SCN5A inhibitor no 2610 tetracaine BLOCKER SCN5A inhibitor no 2706 topiramate BLOCKER SCN5A inhibitor no 2403 ropivacaine BLOCKER SCN5A inhibitor no 2382 riluzole BLOCKER SCN5A inhibitor no 2152 phenytoin BLOCKER SCN5A inhibitor no 2017 oxcarbazepine BLOCKER SCN5A inhibitor no 1999 orphenadrine BLOCKER SCN5A inhibitor no 1842 moracizine BLOCKER SCN5A inhibitor no 1794 mexiletine BLOCKER SCN5A inhibitor no 1700 mepivacaine BLOCKER SCN5A inhibitor no 1097 etidocaine BLOCKER SCN5A inhibitor no 926 disopyramide BLOCKER SCN5A inhibitor no 489 carbamazepine BLOCKER SCN5A inhibitor no 2346 quinidine BLOCKER SCN5A inhibitor no 2291 propafenone BLOCKER SCN5A inhibitor no 1176 flecainide BLOCKER SCN5A inhibitor no 2359 ranolazine BLOCKER SCN5A inhibitor no 4303 eslicarbazepine acetate BLOCKER SCN5A inhibitor no 2270 procainamide BLOCKER SCN5A inhibitor no 2686 tocainide BLOCKER SCN5A inhibitor no 4864 levomilnacipran INHIBITOR SLC6A2 inhibitor no 4283 tapentadol INHIBITOR SLC6A2 inhibitor no 195 amfetamine RELEASING AGENT SLC6A2 inhibitor no 2326 pseudoephedrine RELEASING AGENT SLC6A2 inhibitor no 1339 guanadrel SUBSTRATE SLC6A2 inhibitor no 359 betanidine SUBSTRATE SLC6A2 inhibitor no 191 amoxapine INHIBITOR SLC6A2 inhibitor no 2122 phendimetrazine INHIBITOR SLC6A2 inhibitor no 874 diethylpropion INHIBITOR SLC6A2 inhibitor no 1767 methylphenidate INHIBITOR SLC6A2 inhibitor no 2820 viloxazine INHIBITOR SLC6A2 inhibitor no 329 benzphetamine RELEASING AGENT SLC6A2 inhibitor no 435 bupropion INHIBITOR SLC6A2 inhibitor no 394 bretylium SUBSTRATE SLC6A2 inhibitor no 256 atomoxetine INHIBITOR SLC6A2 inhibitor no 1640 mazindol INHIBITOR SLC6A2 inhibitor no 972 duloxetine INHIBITOR SLC6A2 inhibitor no 4380 desvenlafaxine INHIBITOR SLC6A2 inhibitor no 2813 venlafaxine INHIBITOR SLC6A2 inhibitor no 2758 trimipramine INHIBITOR SLC6A2 inhibitor no 2440 sibutramine INHIBITOR SLC6A2 inhibitor no 2320 protriptyline INHIBITOR SLC6A2 inhibitor no 2140 phentermine INHIBITOR SLC6A2 inhibitor no 2133 phenmetrazine INHIBITOR SLC6A2 inhibitor no 1971 nortriptyline INHIBITOR SLC6A2 inhibitor no 1890 nefazodone INHIBITOR SLC6A2 inhibitor no 1808 milnacipran INHIBITOR SLC6A2 inhibitor no 1634 maprotiline INHIBITOR SLC6A2 inhibitor no 1427 imipramine INHIBITOR SLC6A2 inhibitor no 1342 guanethidine SUBSTRATE SLC6A2 inhibitor no 956 doxepin INHIBITOR SLC6A2 inhibitor no 836 dexmethylphenidate INHIBITOR SLC6A2 inhibitor no 812 desipramine INHIBITOR SLC6A2 inhibitor no 180 amitriptyline INHIBITOR SLC6A2 inhibitor no 701 clomipramine INHIBITOR SLC6A2 inhibitor no 1958 nomifensine INHIBITOR SLC6A2 inhibitor no 1592 lofepramine INHIBITOR SLC6A2 inhibitor no 951 dosulepin INHIBITOR SLC6A2 inhibitor no 841 dexamfetamine INHIBITOR SLC6A2 inhibitor no 4135 lisdexamfetamine RELEASING AGENT SLC6A2 inhibitor no 4501 armodafinil INHIBITOR SLC6A3 inhibitor no 2440 sibutramine INHIBITOR SLC6A3 inhibitor no 2133 phenmetrazine INHIBITOR SLC6A3 inhibitor no 841 dexamfetamine RELEASING AGENT SLC6A3 inhibitor no 435 bupropion INHIBITOR SLC6A3 inhibitor no 2758 trimipramine INHIBITOR SLC6A3 inhibitor no 1732 methamphetamine INHIBITOR SLC6A3 inhibitor no 195 amfetamine RELEASING AGENT SLC6A3 inhibitor no 4135 lisdexamfetamine RELEASING AGENT SLC6A3 inhibitor no 1826 modafinil INHIBITOR SLC6A3 inhibitor no 2122 phendimetrazine INHIBITOR SLC6A3 inhibitor no 874 diethylpropion INHIBITOR SLC6A3 inhibitor no 1767 methylphenidate INHIBITOR SLC6A3 inhibitor no 836 dexmethylphenidate INHIBITOR SLC6A3 inhibitor no 1640 mazindol INHIBITOR SLC6A3 inhibitor no 1958 nomifensine INHIBITOR SLC6A3 inhibitor no 723 cocaine INHIBITOR SLC6A3 inhibitor no 4864 levomilnacipran INHIBITOR SLC6A4 inhibitor no 4806 vortioxetine INHIBITOR SLC6A4 inhibitor no 2758 trimipramine INHIBITOR SLC6A4 inhibitor no 701 clomipramine INHIBITOR SLC6A4 inhibitor no 191 amoxapine INHIBITOR SLC6A4 inhibitor no 1640 mazindol INHIBITOR SLC6A4 inhibitor no 972 duloxetine INHIBITOR SLC6A4 inhibitor no 2436 sertraline INHIBITOR SLC6A4 inhibitor no 4380 desvenlafaxine INHIBITOR SLC6A4 inhibitor no 2813 venlafaxine INHIBITOR SLC6A4 inhibitor no 2717 trazodone INHIBITOR SLC6A4 inhibitor no 2440 sibutramine INHIBITOR SLC6A4 inhibitor no 2320 protriptyline INHIBITOR SLC6A4 inhibitor no 1971 nortriptyline INHIBITOR SLC6A4 inhibitor no 1890 nefazodone INHIBITOR SLC6A4 inhibitor no 1808 milnacipran INHIBITOR SLC6A4 inhibitor no 1427 imipramine INHIBITOR SLC6A4 inhibitor no 1230 fluvoxamine INHIBITOR SLC6A4 inhibitor no 1209 fluoxetine INHIBITOR SLC6A4 inhibitor no 1053 escitalopram INHIBITOR SLC6A4 inhibitor no 663 citalopram INHIBITOR SLC6A4 inhibitor no 618 chlorphentermine SUBSTRATE SLC6A4 inhibitor no 180 amitriptyline INHIBITOR SLC6A4 inhibitor no 1592 lofepramine INHIBITOR SLC6A4 inhibitor no 951 dosulepin INHIBITOR SLC6A4 inhibitor no 2068 paroxetine INHIBITOR SLC6A4 inhibitor no 4223 vilazodone INHIBITOR SLC6A4 inhibitor no 4381 dapoxetine INHIBITOR SLC6A4 inhibitor no 5027 rolapitant ANTAGONIST TACR1 inhibitor no 4898 netupitant ANTAGONIST TACR1 inhibitor no 4470 fosaprepitant ANTAGONIST TACR1 inhibitor no 230 aprepitant ANTAGONIST TACR1 inhibitor no 4401 casopitant ANTAGONIST TACR1 inhibitor no 5283 fosnetupitant ANTAGONIST TACR1 inhibitor no 2354 ramatroban INVERSE AGONIST TBXA2R inhibitor no 5048 pitolisant INVERSE AGONIST HRH3 inhibitor no 346 betahistine INVERSE AGONIST HRH3 inhibitor no 3070 articaine BLOCKER SCN5A inhibitor yes 4359 bosutinib INHIBITOR SRC inhibitor yes 4359 bosutinib INHIBITOR ABL1 inhibitor yes 399 bromazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation yes 700 clomifene MODULATOR ESR1 activation yes 4187 crizotinib INHIBITOR ALK inhibitor yes 4187 crizotinib INHIBITOR MET inhibitor yes 1000157 cyproterone MODULATOR AR activation yes 818 desogestrel MODULATOR PGR activation yes 842 dextromethorphan INHIBITOR GRIN1 inhibitor yes 995 eletriptan ANTAGONIST HTR1B inhibitor yes 995 eletriptan ANTAGONIST HTR1D inhibitor yes 995 eletriptan ANTAGONIST HTR1F inhibitor yes 1059 estradiol cypionate MODULATOR ESR1 activation yes 1110 etonogestrel MODULATOR PGR activation yes 1000149 fludrocortisone INHIBITOR NR3C2 inhibitor yes 1191 fludrocortisone acetate INHIBITOR NR3C2 inhibitor yes 1282 gefitinib INHIBITOR EGFR inhibitor yes 1547 lansoprazole INHIBITOR ATP4A inhibitor yes 1547 lansoprazole INHIBITOR ATP4B inhibitor yes 4308 lasofoxifene MODULATOR ESR1 activation yes 1752 levomepromazine ANTAGONIST DRD2 inhibitor yes 1608 lormetazepam POSITIVE ALLOSTERIC MODULATOR GABRA1 activation yes 1667 megestrol acetate MODULATOR PGR activation yes 2107 periciazine ANTAGONIST DRD2 inhibitor yes 2255 pregabalin INHIBITOR CACNA2D1 inhibitor yes 2255 pregabalin INHIBITOR CACNA2D2 inhibitor yes 458 scopolamine butylbromide ANTAGONIST CHRM1 inhibitor yes 2544 sunitinib INHIBITOR KDR inhibitor yes 2579 tegaserod ANTAGONIST HTR4 inhibitor yes 2655 tibolone MODULATOR ESR1 activation yes 5227 valbenazine INHIBITOR SLC18A2 inhibitor yes 2803 valproic acid INHIBITOR ALDH5A1 inhibitor yes 4178 vandetanib INHIBITOR EGFR inhibitor yes 4189 hydroxyprogesterone caproate AGONIST PGR activation no 4942 lenvatinib INHIBITOR FLT1 inhibitor no 4942 lenvatinib INHIBITOR KDR inhibitor no 4942 lenvatinib INHIBITOR FLT4 inhibitor no 4942 lenvatinib INHIBITOR FGFR1 inhibitor no 4942 lenvatinib INHIBITOR PDGFRA inhibitor no 4942 lenvatinib INHIBITOR KIT inhibitor no 4942 lenvatinib INHIBITOR RET inhibitor no 4715 cabozantinib INHIBITOR KDR inhibitor no 4715 cabozantinib INHIBITOR MET inhibitor no 4715 cabozantinib INHIBITOR RET inhibitor no 4715 cabozantinib INHIBITOR TEK inhibitor no 4715 cabozantinib INHIBITOR FLT3 inhibitor no 4715 cabozantinib INHIBITOR KIT inhibitor no 2722 tretinoin AGONIST RARG activation no 2722 tretinoin AGONIST RARB activation no 2852 ximelagatran INHIBITOR F2 inhibitor no 2609 tetrabenazine INHIBITOR SLC18A2 inhibitor no 2370 reserpine INHIBITOR SLC18A2 inhibitor no 2351 raloxifene MODULATOR ESR2 activation no 1255 fulvestrant ANTAGONIST ESR2 inhibitor no 2279 progesterone AGONIST PGR activation no 1968 norgestimate AGONIST PGR activation no 1963 norethindrone acetate AGONIST PGR activation no 1962 norethisterone AGONIST PGR activation no 1659 medroxyprogesterone AGONIST PGR activation no 1572 levonorgestrel AGONIST PGR activation no 1095 etynodiol AGONIST PGR activation no 968 drospirenone AGONIST PGR activation no 2722 tretinoin AGONIST RARA activation no 1255 fulvestrant ANTAGONIST ESR1 inhibitor no 1082 ethinylestradiol AGONIST ESR1 activation no 1057 estradiol AGONIST ESR1 activation no 968 drospirenone ANTAGONIST NR3C2 inhibitor no 2342 quinestrol AGONIST ESR1 activation no 975 dydrogesterone AGONIST PGR activation no 870 dienestrol AGONIST ESR1 activation no 385 bivalirudin INHIBITOR F2 inhibitor no 362 bezafibrate AGONIST PPARA activation no 76 acipimox AGONIST HCAR2 activation no 694 clofibrate AGONIST PPARA activation no 1714 mestranol AGONIST ESR1 activation no 282 baclofen AGONIST GABBR1|GABBR2 activation no 875 diethylstilbestrol AGONIST ESR1 activation no 3188 estrone AGONIST ESR1 activation no 658 ciprofibrate AGONIST PPARA activation no 1965 norethynodrel AGONIST PGR activation no 2351 raloxifene ANTAGONIST ESR1 inhibitor no 2571 tazarotene AGONIST RARB activation no 2571 tazarotene AGONIST RARA activation no 2571 tazarotene AGONIST RARG activation no 1064 estradiol valerate AGONIST ESR1 activation no 2561 tamoxifen MODULATOR ESR1 activation no 4166 ulipristal ANTAGONIST PGR inhibitor no 2459 sorafenib INHIBITOR FLT3 inhibitor no 2459 sorafenib INHIBITOR FLT1 inhibitor no 2459 sorafenib INHIBITOR KDR inhibitor no 2459 sorafenib INHIBITOR RAF1 inhibitor no 2459 sorafenib INHIBITOR BRAF inhibitor no 2459 sorafenib INHIBITOR PDGFRB inhibitor no 2459 sorafenib INHIBITOR KIT inhibitor no 2459 sorafenib INHIBITOR FLT4 inhibitor no 2459 sorafenib INHIBITOR RET inhibitor no 362 bezafibrate INHIBITOR HMGCR inhibitor no 4225 axitinib INHIBITOR FLT1 inhibitor no 4225 axitinib INHIBITOR KDR inhibitor no 4225 axitinib INHIBITOR FLT4 inhibitor no 4334 bazedoxifene MODULATOR ESR1 activation no 4334 bazedoxifene MODULATOR ESR2 activation no 4497 estradiol acetate AGONIST ESR1 activation no 5062 osimertinib INHIBITOR EGFR inhibitor no 3187 estriol AGONIST ESR1 activation no