Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung
Description
Code and data for the preprint "Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung".
Metagenomic analysis
- uses `targets` (workflow manager) and `renv` (environment manager) R packages.
- calling `targets::tar_make()`, once the environment is configured using renv and a separate project has been created (with the exact file structure including the data), should run the entire pipeline, creating a _targets folder with all the .rds files
- independent objects can be explored using `targets::tar_load(obj)` or `targets::tar_read(plot)`
Targets user manual for more information. Preprocessing/QC scripts can be provided upon reasonable request.
Files
opitz_2023_zenodo.zip
Files
(1.8 GB)
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