Published April 3, 2023
| Version v1
Dataset
Open
Epiphany model files
Description
Epiphany, a neural network to predict cell-type-specific Hi-C contact maps from widely available epigenomic tracks. Epiphany uses bidirectional long short-term memory layers to capture long-range dependencies and optionally a generative adversarial network architecture to encourage contact map realism. Epiphany shows excellent generalization to held-out chromosomes within and across cell types, yields accurate TAD and interaction calls, and predicts structural changes caused by perturbations of epigenomic signals.
Files
Files
(4.8 GB)
Name | Size | Download all |
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md5:c5960db549639ed0bca0c7bbb2c835df
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1.2 GB | Download |
md5:f49a204a3da859569a252694975793df
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2.5 GB | Download |
md5:dde7edc93a39b75c34b87bb51a02fc7f
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366.7 MB | Download |
md5:4f1b7daa947c466e3dbfc6084ef5432b
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831.1 MB | Download |