Published April 3, 2023 | Version v1
Dataset Open

Epiphany model files

Description

Epiphany, a neural network to predict cell-type-specific Hi-C contact maps from widely available epigenomic tracks. Epiphany uses bidirectional long short-term memory layers to capture long-range dependencies and optionally a generative adversarial network architecture to encourage contact map realism. Epiphany shows excellent generalization to held-out chromosomes within and across cell types, yields accurate TAD and interaction calls, and predicts structural changes caused by perturbations of epigenomic signals. 

 

**Related repo**: github, preprint

Files

Files (4.8 GB)

Name Size Download all
md5:c5960db549639ed0bca0c7bbb2c835df
1.2 GB Download
md5:f49a204a3da859569a252694975793df
2.5 GB Download
md5:dde7edc93a39b75c34b87bb51a02fc7f
366.7 MB Download
md5:4f1b7daa947c466e3dbfc6084ef5432b
831.1 MB Download