Protocol for an individual patient data meta-analysis for the Hyperion and TTM2-trials for participants with a non-shockable rhythm

The Hyperion trial (Lascarrou et al, NEJM 2019) and the TTM2 trial (Dankiewicz et al, NEJM 2021)) were randomized clinical trials comparing 33°C targeted temperature management with normothermia in patients with a cardiac arrest. In this individual patient data meta analysis we have analysed the participants with an out-of-hospital cardiac arrest with initial non-shockable rhythm.