Raw data.zip
Raw data
Figure 1
DLS
Silica 1 um
SiO2 Cy5 1 um_DLS_H20_90deg_final.jpg
141.8 kB
SiO2 Cy5 1 um_H20_20ugmL
SIO2 CY5 1 um_H20
90°
SIO2 CY5 1 um_H2020.dat
17.6 kB
SIO2 CY5 1 um_H2021.dat
17.4 kB
SIO2 CY5 1 um_H2022.dat
17.4 kB
SIO2 CY5 1 um_H2023.dat
17.6 kB
SIO2 CY5 1 um_H2024.dat
17.6 kB
SIO2 CY5 1 um_H2025.dat
17.6 kB
SIO2 CY5 1 um_H2026.dat
17.4 kB
SIO2 CY5 1 um_H2027.dat
17.6 kB
SIO2 CY5 1 um_H2028.dat
17.6 kB
SIO2 CY5 1 um_H2029.dat
17.8 kB
SiO2 Cy5 1 um_cRPMI_20ugmL
90°
SiO2_1um_cRPMI_vv.dat
3.5 kB
SiO2_1um_cRPMI_vv0.dat
11.0 kB
SiO2_1um_cRPMI_vv1.dat
11.2 kB
SiO2_1um_cRPMI_vv10.dat
11.2 kB
SiO2_1um_cRPMI_vv11.dat
11.2 kB
SiO2_1um_cRPMI_vv12.dat
11.0 kB
SiO2_1um_cRPMI_vv13.dat
11.1 kB
SiO2_1um_cRPMI_vv14.dat
11.2 kB
SiO2_1um_cRPMI_vv15.dat
11.0 kB
SiO2_1um_cRPMI_vv16.dat
11.2 kB
SiO2_1um_cRPMI_vv17.dat
11.2 kB
SiO2_1um_cRPMI_vv18.dat
11.2 kB
SiO2_1um_cRPMI_vv19.dat
11.2 kB
SiO2_1um_cRPMI_vv2.dat
11.0 kB
SiO2_1um_cRPMI_vv20.dat
11.2 kB
SiO2_1um_cRPMI_vv21.dat
11.0 kB
SiO2_1um_cRPMI_vv22.dat
11.2 kB
SiO2_1um_cRPMI_vv23.dat
11.0 kB
SiO2_1um_cRPMI_vv24.dat
11.4 kB
SiO2_1um_cRPMI_vv25.dat
11.2 kB
SiO2_1um_cRPMI_vv26.dat
11.0 kB
SiO2_1um_cRPMI_vv27.dat
11.0 kB
SiO2_1um_cRPMI_vv28.dat
11.2 kB
SiO2_1um_cRPMI_vv29.dat
11.0 kB
SiO2_1um_cRPMI_vv3.dat
11.2 kB
SiO2_1um_cRPMI_vv30.dat
11.2 kB
SiO2_1um_cRPMI_vv31.dat
11.2 kB
SiO2_1um_cRPMI_vv32.dat
11.2 kB
SiO2_1um_cRPMI_vv33.dat
11.0 kB
SiO2_1um_cRPMI_vv34.dat
11.0 kB
SiO2_1um_cRPMI_vv35.dat
11.2 kB
SiO2_1um_cRPMI_vv36.dat
11.2 kB
SiO2_1um_cRPMI_vv4.dat
11.2 kB
SiO2_1um_cRPMI_vv5.dat
11.2 kB
SiO2_1um_cRPMI_vv6.dat
11.4 kB
SiO2_1um_cRPMI_vv7.dat
11.0 kB
SiO2_1um_cRPMI_vv8.dat
11.0 kB
SiO2_1um_cRPMI_vv9.dat
11.0 kB
Thumbs.db
14.8 kB
SiO2_1um_cRPMI_vv_90deg.jpg
142.3 kB
Silica 130 nm
DLS_130 nm SiO2 Cy5_cRPMI_90deg_final.jpg
137.9 kB
SIO2 CY5 130 nm_cRPMI_24h
90°
DLS_130 nm SiO2 Cy5_cRPMI_24h0.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h1.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h2.dat
23.8 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h3.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h4.dat
23.8 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h5.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h6.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h7.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h8.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h9.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h.dat
1.1 kB
SiO2 Cy5 130 nm_H20
90°
SiO2 Cy5 130 nm_H2020.dat
17.5 kB
SiO2 Cy5 130 nm_H2021.dat
17.8 kB
SiO2 Cy5 130 nm_H2022.dat
17.8 kB
SiO2 Cy5 130 nm_H2023.dat
17.5 kB
SiO2 Cy5 130 nm_H2024.dat
17.6 kB
SiO2 Cy5 130 nm_H2025.dat
17.8 kB
SiO2 Cy5 130 nm_H2026.dat
17.4 kB
SiO2 Cy5 130 nm_H2027.dat
17.7 kB
SiO2 Cy5 130 nm_H2028.dat
17.8 kB
SiO2 Cy5 130 nm_H2029.dat
17.7 kB
SiO2 Cy5 130 nm_H20.dat
2.9 kB
SiO2 Cy5 130 nm_H20_90deg_final.jpg
128.4 kB
cRPMI
90°
cRPMI20.dat
17.7 kB
cRPMI21.dat
17.6 kB
cRPMI22.dat
17.8 kB
cRPMI23.dat
17.8 kB
cRPMI24.dat
17.5 kB
cRPMI25.dat
17.7 kB
cRPMI26.dat
17.5 kB
cRPMI27.dat
17.5 kB
cRPMI28.dat
17.6 kB
cRPMI29.dat
17.6 kB
cRPMI.dat
2.9 kB
TEM
Silica 1 um
Results_Sio2Cy5 1um_0002_1.csv
25.3 kB
Results_Sio2Cy5 1um_0003_1.csv
16.1 kB
SiO2Cy5 1um_07012022_1_0000_1.ser
8.4 MB
SiO2Cy5 1um_07012022_1_0001_1.jpg
350.0 kB
SiO2Cy5 1um_07012022_1_0002_1.jpg
738.4 kB
SiO2Cy5 1um_07012022_1_0002_1.ser
8.4 MB
SiO2Cy5 1um_07012022_1_0003_1.ser
8.4 MB
Sio2Cy5 1um_0002_1_watershed.jpg
197.0 kB
Sio2Cy5 1um_0003_1_watershed.jpg
193.4 kB
Silica 130 nm
Results_07012022_1_0000_1.csv
171.0 kB
SiO2Cy5 120nm_07012022_1_0000_1.jpg
567.7 kB
SiO2Cy5 120nm_07012022_1_0003_1.jpg
782.1 kB
SiO2Cy5 120nm_07012022_1_0003_1.ser
8.4 MB
Silica NPs histogram.pzfx
69.7 kB
TEM calculation of NPs.xlsx
71.7 kB
Figure 2
CLSM
24 h
1 um 24h_for paper.jpg
232.3 kB
130 nm 24h_for paper.jpg
241.7 kB
Thumbs.db
33.3 kB
XZ 149_1 um 24h_for paper.tif
635.1 kB
XZ 20_130 nm 24h_ for paper.tif
602.8 kB
6 h
1 um 6h_for paper.jpg
100.7 kB
130 nm 6h treated_for paper.jpg
234.6 kB
Control 6h_for paper.jpg
104.0 kB
Thumbs.db
64.5 kB
XZ 278_130 nm 6h_for paper.tif
1.0 MB
XZ 66_1 um 6h_for paper.tif
229.4 kB
XZ 709 Control 6h_for paper.tif
213.8 kB
Figure 3
Flow cytometry
08122021_SIO2 NPs_EGF_EIPA_6h
09-Dec-2021.wsp
716.0 kB
A549 P10_117nm.fcs
681.7 kB
A549 P10_1um.fcs
764.2 kB
A549 P10_Control.fcs
748.1 kB
A549 P10_Dextran.fcs
554.9 kB
A549 P10_EGF+117nm.fcs
755.4 kB
A549 P10_EGF+1um.fcs
765.8 kB
A549 P10_EGF+Dextran.fcs
756.5 kB
A549 P10_EIPA+117.fcs
578.6 kB
A549 P10_EIPA+1um.fcs
515.6 kB
A549 P10_EIPA+Dextran.fcs
478.3 kB
A549 P10_EIPA+EGF+117nm.fcs
549.3 kB
A549 P10_EIPA+EGF+1um.fcs
756.2 kB
A549 P10_EIPA+EGF+dextran.fcs
722.2 kB
Table.xls
6.1 kB
a549 p11_117nm.fcs
765.0 kB
a549 p11_1um.fcs
759.2 kB
a549 p11_Control.fcs
751.9 kB
a549 p11_Dextran.fcs
747.7 kB
a549 p11_EGF+117nm.fcs
762.1 kB
a549 p11_EGF+1um.fcs
774.4 kB
a549 p11_EGF+Dextran.fcs
757.3 kB
a549 p11_EIPA+117.fcs
647.7 kB
a549 p11_EIPA+1um.fcs
649.9 kB
a549 p11_EIPA+Dextran.fcs
722.1 kB
a549 p11_EIPA+EGF+117nm.fcs
678.8 kB
a549 p11_EIPA+EGF+1um.fcs
621.3 kB
a549 p11_EIPA+EGF+dextran.fcs
570.7 kB
09122021_SIO2 NPs_EGF_EIPA_24h_
24h_p10 and p11.wsp
863.9 kB
24h_p10 and p11.xls
6.1 kB
A549 P10_117nm.fcs
758.3 kB
A549 P10_1um.fcs
765.7 kB
A549 P10_Control.fcs
746.2 kB
A549 P10_Dextran.fcs
756.4 kB
A549 P10_EGF+117nm.fcs
760.8 kB
A549 P10_EGF+1um.fcs
764.3 kB
A549 P10_EGF+Dextran.fcs
757.4 kB
A549 P10_EIPA+117nm.fcs
788.3 kB
A549 P10_EIPA+1um.fcs
823.1 kB
A549 P10_EIPA+EGF+117nm.fcs
801.5 kB
A549 P10_EIPA+EGF+1um.fcs
787.0 kB
a549 p11_117nm.fcs
778.6 kB
a549 p11_1um.fcs
781.3 kB
a549 p11_Control.fcs
774.1 kB
a549 p11_Dextran.fcs
756.1 kB
a549 p11_EGF+117nm.fcs
765.3 kB
a549 p11_EGF+1um.fcs
794.4 kB
a549 p11_EGF+Dextran.fcs
764.5 kB
a549 p11_EIPA+117.fcs
842.3 kB
a549 p11_EIPA+1um.fcs
797.0 kB
a549 p11_EIPA+EGF+117nm.fcs
806.4 kB
a549 p11_EIPA+EGF+1um.fcs
794.6 kB
16122021_SIO2 NPs_EGF_EIPA_24h__002
16-Dec-2021_data_a549_p12_24h.wsp
343.2 kB
A549 P12_117nm.fcs
744.9 kB
A549 P12_1um.fcs
745.1 kB
A549 P12_Control.fcs
746.7 kB
A549 P12_Dextran.fcs
743.4 kB
A549 P12_EGF+117nm.fcs
753.4 kB
A549 P12_EGF+1um.fcs
757.0 kB
A549 P12_EGF+Dextran.fcs
751.2 kB
A549 P12_EIPA+117nm.fcs
775.2 kB
A549 P12_EIPA+1um.fcs
788.3 kB
A549 P12_EIPA+Dextran.fcs
794.9 kB
A549 P12_EIPA+EGF+117nm.fcs
795.4 kB
A549 P12_EIPA+EGF+1um.fcs
722.7 kB
Median Fluorescence intensity_24h_A549_p12.xls
5.6 kB
16122021_SIO2 NPs_EGF_EIPA_6h__001_p12
16-Dec-2021_data_a549_p12_6h.wsp
327.0 kB
A549 P12_117nm.fcs
375.4 kB
A549 P12_1um.fcs
380.0 kB
A549 P12_Control.fcs
372.0 kB
A549 P12_Dextran.fcs
377.4 kB
A549 P12_EGF+117nm.fcs
375.6 kB
A549 P12_EGF+1um.fcs
381.2 kB
A549 P12_EGF+Dextran.fcs
375.8 kB
A549 P12_EIPA+117nm.fcs
374.5 kB
A549 P12_EIPA+1um.fcs
375.6 kB
A549 P12_EIPA+EGF+117nm.fcs
374.4 kB
A549 P12_EIPA+EGF+1um.fcs
373.0 kB
Median fluorescence intensity_FITC and Cy5_a549_p12_6h.xls
5.1 kB
Flow cytometry results_Final.xls
49.2 kB
Raw data_Flow repository.txt
125 Bytes
Figure 4
Colocalization
19012022_Coloclization_SiO2 NPs and lysotracker_EGFR_6h
1 um SiO2 6h treated.tif
126.9 MB
120 nm SiO2 6h treated.tif
136.6 MB
Control 6h_treated.tif
78.4 MB
EGF + 1 um SiO2 6h treated.tif
136.6 MB
EGF + 120 nm SiO2 6h_treated.tif
146.3 MB
EGF 6h_treated.tif
84.9 MB
Thumbs.db
108.5 kB
28012022_SiO2 NPs_EGFR_ 24h
1 um 24h treated.tif
361.3 MB
Control 24h treated.tif
382.5 MB
EGF + 1 um 24h treated.tif
382.5 MB
EGF + 120 nm 24h treated.tif
403.7 MB
EGF 24h treated.tif
340.1 MB
Thumbs.db
553.5 kB
Colocalization results_final_cell by cell_24h.xlsx
97.9 kB
Colocalization results_final_cell by cell_6h.xlsx
81.9 kB
Figure 5
Wound healing assay
15092021_wound healing assay_A549_EGF_SiO2 NPs
117 24h.bmp
2.8 MB
117 nm 0h.bmp
2.8 MB
117 nm 6h.bmp
2.8 MB
1um 0h.bmp
2.8 MB
1um 24h.bmp
2.8 MB
1um 6h.bmp
2.8 MB
Control 0h.bmp
2.8 MB
Control 24h.bmp
2.8 MB
Control 6h.bmp
2.8 MB
Drawing of Control 0h.jpg
32.3 kB
Drawing of Control 24h.jpg
44.0 kB
Drawing of Control 6h.jpg
40.4 kB
Drawing of EGF + 117nm 0h.jpg
31.7 kB
Drawing of EGF + 117nm 24h.jpg
41.8 kB
Drawing of EGF + 1um 24h.jpg
55.2 kB
Drawing of EGF 0h.jpg
46.0 kB
Drawing of EGF 6h.jpg
44.2 kB
EGF + 117nm 0h.bmp
2.8 MB
EGF + 117nm 24h.bmp
2.8 MB
EGF + 117nm 6h.bmp
2.8 MB
EGF + 1um 0h.bmp
2.8 MB
EGF + 1um 24h.bmp
2.8 MB
EGF + 1um 6h.bmp
2.8 MB
EGF 0h.bmp
2.8 MB
EGF 24h.bmp
2.8 MB
EGF 6h.bmp
2.8 MB
Results 1 um_0h.csv
39 Bytes
Results 1 um_24h.csv
39 Bytes
Results 1 um_6h.csv
39 Bytes
Results 130 nm_0h.csv
38 Bytes
Results 130 nm_6h.csv
38 Bytes
Results 130nm_24h.csv
36 Bytes
Results Control_0h.csv
39 Bytes
Results Control_24h.csv
39 Bytes
Results Control_6h.csv
39 Bytes
Results EGF+1 um_0h.csv
42 Bytes
Results EGF+1 um_24h.csv
177 Bytes
Results EGF+1 um_6h.csv
42 Bytes
Results EGF+130 nm_0h.csv
44 Bytes
Results EGF+130 nm_24h.csv
73 Bytes
Results EGF+130nm_6h.csv
44 Bytes
Results EGF_0h.csv
35 Bytes
Results EGF_24h.csv
95 Bytes
Results EGF_6h.csv
35 Bytes
Results_total area.csv
54 Bytes
Thumbs.db
466.4 kB
22092021_wound healing assay_A549_EGF_SIO2NPs
1 um 0h.bmp
2.8 MB
1 um 0h_treated.jpg
52.0 kB
117 nm 0h.bmp
2.8 MB
117 nm 0h_treated.jpg
41.0 kB
117 nm 24h.bmp
2.8 MB
117 nm 24h_treated.jpg
68.5 kB
117 nm 6h.bmp
2.8 MB
117 nm 6h_treated.jpg
54.4 kB
1um 24h.bmp
2.8 MB
1um 24h_treated.jpg
48.7 kB
1um 6h.bmp
2.8 MB
1um 6h_treated.jpg
72.4 kB
Control 0h.bmp
2.8 MB
Control 0h_treated.jpg
55.1 kB
Control 24h.bmp
2.8 MB
Control 24h_treated.jpg
61.2 kB
Control 6h.bmp
2.8 MB
Control 6h_treated.jpg
61.6 kB
EGF +117nm 24h.bmp
2.8 MB
EGF +117nm 24h_treated.jpg
65.6 kB
EGF 0h.bmp
2.8 MB
EGF 0h_results.csv
45 Bytes
EGF 0h_treated.jpg
52.3 kB
EGF 24h.bmp
2.8 MB
EGF 24h_treated.jpg
66.1 kB
EGF 6h.bmp
2.8 MB
EGF 6h_treated.jpg
66.8 kB
EGF+1 um 0h.bmp
2.8 MB
EGF+1 um 0h_treated.jpg
56.0 kB
EGF+1 um 24h.bmp
2.8 MB
EGF+1 um 24h_treated.jpg
70.7 kB
EGF+1 um 6h.bmp
2.8 MB
EGF+1 um 6h_treated.jpg
59.0 kB
EGF+117nm 0h.bmp
2.8 MB
EGF+117nm 0h_treated.jpg
46.9 kB
EGF+117nm 6h.bmp
2.8 MB
EGF+117nm 6h_treated.jpg
42.6 kB
Results_1 um 0h.csv
46 Bytes
Results_1 um 24h.csv
36 Bytes
Results_1 um 6h.csv
45 Bytes
Results_117 nm 24h.csv
49 Bytes
Results_117 nm_0h.csv
48 Bytes
Results_117 nm_6h.csv
48 Bytes
Results_Control 24h.csv
50 Bytes
Results_Control 6h.csv
49 Bytes
Results_EGF +117 nm_0h.csv
51 Bytes
Results_EGF 1um 6h.csv
50 Bytes
Results_EGF 24h.csv
45 Bytes
Results_EGF 6h.csv
45 Bytes
Results_EGF+1um_0h.csv
50 Bytes
Results_EGF+1um_24h.csv
86 Bytes
Results_control 0h.csv
49 Bytes
Thumbs.db
552.4 kB
Final data_% Confluency.xlsx
47.7 kB
Figure 6
1 h
EGFR P19.gel
3.1 MB
EGFR P19_original.jpg
78.0 kB
EGFR P19_thresholding_results.csv
72 Bytes
EGFR_A549_P4_16092021.gel
3.1 MB
EGFR_A549_P4_16092021.jpg
11.7 kB
EGFR_A549_P4_16092021_thresholding_results.csv
72 Bytes
EGFR_P20_rep_1h.gel
3.1 MB
EGFR_P20_rep_1h_THRESHOLD.jpg
8.6 kB
EGFR_p14_1h.gel
3.1 MB
EGFR_p14_1h.jpg
9.8 kB
GAPDH P19.gel
3.1 MB
GAPDH P19_original.jpg
37.3 kB
GAPDH P19_threshold_results.csv
68 Bytes
GAPDH_A549_P4_16092021.gel
3.1 MB
GAPDH_A549_P4_16092021.jpg
7.0 kB
GAPDH_A549_P4_16092021_results.csv
72 Bytes
GAPDH_P20_rep_1h.gel
3.1 MB
GAPDH_P20_rep_1h_threshold.jpg
9.2 kB
GAPDH_p14_1h.gel
3.1 MB
GAPDH_p14_1h.jpg
8.7 kB
Results_EGFR_1h_P20.csv
72 Bytes
Results_EGFR_P14 1h.csv
72 Bytes
Results_GAPDH_1h_P20.csv
72 Bytes
Results_GAPDH_p14_1h.csv
72 Bytes
24 h
13082021_EGFR_A549_p22.gel
3.1 MB
13082021_EGFR_A549_p22.jpg
6.5 kB
13082021_GAPDH_A549_p22.gel
3.1 MB
13082021_GAPDH_A549_p22.jpg
12.0 kB
A549_P4_EGFR.gel
3.1 MB
A549_P4_EGFR_original_24 h.tif
7.4 MB
A549_P4_GAPDH.gel
3.1 MB
A549_P4_GAPDH_original_24h.tif
7.6 MB
EGFR P21 19082021.gel
3.1 MB
EGFR_p10_24h_flip vertically.gel
3.1 MB
EGFR_p10_24h_flip vertically.jpg
10.1 kB
GAPDH P21 19082021.gel
3.1 MB
GAPDH P21 19082021_thresholding.jpg
15.2 kB
GAPDH_p10_24h_flip horizontally.gel
3.1 MB
GAPDH_p10_24h_flip horizontally.jpg
11.5 kB
Results_A549_EGFR_P4.csv
72 Bytes
Results_A549_EGFR_p22.csv
71 Bytes
Results_A549_P4_GAPDH.csv
72 Bytes
Results_EGFR_P10_24h.csv
71 Bytes
Results_EGFR_P21.csv
72 Bytes
Results_GAPDH_P21.csv
72 Bytes
Results_GAPDH_p10_24h.csv
72 Bytes
Results_a549_gapdh_p22.csv
72 Bytes
Western blot EGFR
Uncropped blots_Western Blot
Figure 6A_EGFR.tif
7.7 MB
Figure 6A_GAPDH.tif
5.2 MB
Figure 6B_EGFR.tif
7.4 MB
Figure 6B_GAPDH.tif
7.6 MB
Thumbs.db
51.2 kB
Figure 7
1 h
03032022_p-erk_A549_p20_1h and 6h.gel
3.1 MB
03032022_p-erk_A549_p20_1h_results.csv
86 Bytes
03032022_total erk_A549_p20_1h and 6h.gel
3.1 MB
03032022_total erk_A549_p20_1h_results.csv
86 Bytes
03032022_tubulin_A549_p20_1h and 6h.gel
3.1 MB
03032022_tubulin_A549_p20_1h_results.csv
86 Bytes
04032022_p-erk12_A549_p6_1h and 6h.gel
3.1 MB
04032022_p-erk12_A549_p6_1h_results.csv
85 Bytes
04032022_total erk 12_A549_p6_1h and 6h.gel
3.1 MB
04032022_total erk 12_A549_p6_1h_results.csv
111 Bytes
04032022_tubulin_A549_p6_1h and 6h.gel
3.1 MB
04032022_tubulin_A549_p6_1h_results.csv
86 Bytes
17032022_p-erk12_p8 1h.gel
3.1 MB
17032022_total-erk12_p8 1h and 24h.gel
3.1 MB
17032022_tubulin_p8 1h and 24h.gel
3.1 MB
Results_p-erk_p8 1h.csv
85 Bytes
Results_total-erk_p8 1h.csv
86 Bytes
Results_tubulin_p8 1h.csv
86 Bytes
24 h
02032022_p-ERK12_A549_p8_24h.gel
3.1 MB
02032022_totalERK12_A549_p8_24h.gel
3.1 MB
03032022_p-ERK12_A549_p8_24h_2nd.gel
3.1 MB
04032022_p-erk12_A549_p6_24h.gel
3.1 MB
04032022_p-erk12_A549_p6_24h_results.csv
86 Bytes
04032022_total erk 12_A549_p6_24h.gel
3.1 MB
04032022_total erk 12_A549_p6_24h_results.csv
86 Bytes
04032022_tubulin_A549_p6_24h.gel
3.1 MB
04032022_tubulin_A549_p6_24h_results.csv
85 Bytes
13042022_p-erk12 SIO2 NPs_24h_p20.gel
3.1 MB
13042022_total erk12 SIO2 NPs_24h_p20.gel
3.1 MB
13042022_tubulin SIO2 NPs_24h_p20.gel
3.1 MB
23032022_p-erk_A549_p8_24_results.csv
85 Bytes
23032022_total-erk_A549_p8_24_results.csv
86 Bytes
23032022_tubulin_A549_p8_24_results.csv
86 Bytes
Results_p20_24h_pERK.csv
86 Bytes
Results_p20_24h_total ERK.csv
83 Bytes
Results_p20_24h_tubulin.csv
86 Bytes
6 h
03032022_p-erk_A549_p20_1h and 6h.gel
3.1 MB
03032022_p-erk_A549_p20_6h_results.csv
86 Bytes
03032022_total erk_A549_p20_1h and 6h.gel
3.1 MB
03032022_total erk_A549_p20_6h_results.csv
86 Bytes
03032022_tubulin_A549_p20_1h and 6h.gel
3.1 MB
03032022_tubulin_A549_p20_6h_results.csv
86 Bytes
09032022_p-erk12_A549_p8_6h.gel
3.1 MB
09032022_p-erk12_A549_p8_6h_results.csv
84 Bytes
09032022_total erk12_A549_p8_6h.gel
3.1 MB
09032022_total erk12_A549_p8_6h_results.csv
85 Bytes
09032022_tubulin_A549_p8_6h.gel
3.1 MB
09032022_tubulin_A549_p8_6h_results.csv
85 Bytes
17032022_p-erk12_p6 6h and p20 24h.gel
3.1 MB
17032022_total-erk12_p6 6h and p20 24h.gel
3.1 MB
17032022_tubulin_p6 6h and p20 24h.gel
3.1 MB
Results_p-erk_p6 6h.csv
86 Bytes
Results_total-erk_p6 6h.csv
99 Bytes
Results_tubulin_p6 6h.csv
86 Bytes
Western blot ERK12
Figure 7A_p-erk12.tif
2.2 MB
Figure 7A_t-erk12.tif
985.2 kB
Figure 7A_α-tubulin.tif
1.9 MB
Figure 7B_p-erk12.tif
5.6 MB
Figure 7B_t-erk12.tif
6.2 MB
Figure 7B_α-tubulin.tif
4.5 MB
Figure 7C_p-erk12.tif
4.4 MB
Figure 7C_t-erk 12.tif
2.9 MB
Figure 7C_α-tubulin.tif
6.6 MB
Figure S1
DLS
Silica 1 um
SiO2 Cy5 1 um_DLS_H20_90deg_final.jpg
141.8 kB
SiO2 Cy5 1 um_cRPMI_20ugmL
Thumbs.db
14.8 kB
SiO2_1um_cRPMI_vv_90deg.jpg
142.3 kB
Silica 130 nm
DLS_130 nm SiO2 Cy5_cRPMI_90deg_final.jpg
137.9 kB
SIO2 CY5 130 nm_cRPMI_24h
90°
DLS_130 nm SiO2 Cy5_cRPMI_24h0.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h1.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h2.dat
23.8 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h3.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h4.dat
23.8 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h5.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h6.dat
24.0 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h7.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h8.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h9.dat
23.9 kB
DLS_130 nm SiO2 Cy5_cRPMI_24h.dat
1.1 kB
SiO2 Cy5 130 nm_H20
90°
SiO2 Cy5 130 nm_H2020.dat
17.5 kB
SiO2 Cy5 130 nm_H2021.dat
17.8 kB
SiO2 Cy5 130 nm_H2022.dat
17.8 kB
SiO2 Cy5 130 nm_H2023.dat
17.5 kB
SiO2 Cy5 130 nm_H2024.dat
17.6 kB
SiO2 Cy5 130 nm_H2025.dat
17.8 kB
SiO2 Cy5 130 nm_H2026.dat
17.4 kB
SiO2 Cy5 130 nm_H2027.dat
17.7 kB
SiO2 Cy5 130 nm_H2028.dat
17.8 kB
SiO2 Cy5 130 nm_H2029.dat
17.7 kB
SiO2 Cy5 130 nm_H20.dat
2.9 kB
SiO2 Cy5 130 nm_H20_90deg_final.jpg
128.4 kB
cRPMI
90°
cRPMI20.dat
17.7 kB
cRPMI21.dat
17.6 kB
cRPMI22.dat
17.8 kB
cRPMI23.dat
17.8 kB
cRPMI24.dat
17.5 kB
cRPMI25.dat
17.7 kB
cRPMI26.dat
17.5 kB
cRPMI27.dat
17.5 kB
cRPMI28.dat
17.6 kB
cRPMI29.dat
17.6 kB
cRPMI.dat
2.9 kB
Zeta potential
Zeta potential_SiO2 Cy5_1 um_12042022.pdf
195.4 kB
Zeta potential_SiO2 Cy5_130nm_12042022.pdf
198.8 kB
Figure S2
Cytotoxicity_LDH
Calculation LDH.xlsx
37.8 kB
Mitochondrial activity_WST1
Calculation_WST1_.xlsx
27.8 kB
WST1_EGF_SIO2 NPs_with reference wavelenght 650_24h_p16.xls
10.2 kB
WST1_EGF_SIO2 NPs_with reference wavelenght 650_24h_p17.xls
10.1 kB
WST1_EGF_SIO2 NPs_with reference wavelenght 650_48h_p16.xls
10.2 kB
WST1_EGF_SIO2 NPs_with reference wavelenght 650_48h_p17.xls
10.1 kB
WST1_EGF_SiO2 NPs_17022022_24h_p6.xls
10.1 kB
WST1_EGF_SiO2 NPs_17022022_48h_p6.xls
10.2 kB
Figure S3
CLSM
Max proj intens_ 1 um 24h_EGFR_for paper.jpg
1.2 MB
Max proj intens_ 1 um 24h_particles_for paper.jpg
390.5 kB
Max proj intens_ 130 nm 24h_EGFR_for paper.jpg
1.1 MB
Max proj intens_ 130 nm 24h_merged_for paper.jpg
1.2 MB
Max proj intens_ 130 nm 24h_particles_for paper.jpg
307.8 kB
Max proj intens_1 um 24h_merged_for paper.jpg
1.3 MB
Max proj intens_EGF + 1 um 24h_EGFR_for paper.jpg
1.1 MB
Max proj intens_EGF + 1 um 24h_merged_for paper.jpg
1.1 MB
Max proj intens_EGF + 1 um 24h_particles_for paper.jpg
319.9 kB
Max proj intens_EGF + 130 nm 24h_for paper.jpg
1.2 MB
Max proj intens_EGF + 130 nm 24h_merged_for paper.jpg
1.3 MB
Max proj intens_EGF + 130 nm 24h_particles_for paper.jpg
452.6 kB
Thumbs.db
208.9 kB
Figure S4
WST1
Calculation_WST1_.xlsx
27.8 kB