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{"sheet":"Sheet1","index":0,"n_rows":125,"n_cols":19,"rows_kept":125,"merged":[[1,1,1,2],[1,4,1,5],[2,8,2,9],[14,1,14,2],[27,1,27,2],[27,4,27,5],[27,7,27,8],[28,11,28,12],[38,1,38,2],[52,1,52,7],[53,2,53,4],[53,5,53,7],[53,10,53,11],[65,1,65,2],[65,4,65,5],[66,8,66,9],[78,1,78,2],[78,4,78,5],[78,7,78,8],[92,1,92,2],[106,1,106,2],[116,1,116,7],[117,2,117,4],[117,5,117,7],[117,10,117,11]]}
["Figure 4B"]
[null,"N.Ob/BS(/mm)",null,null,"OS/BS(%)",null,null,"Test details"]
[null,"WT","DTAhet",null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,91.243533,64.032291,null,46.2086,14.2741]
[null,87.817141,47.521235,null,44.6246,33.9596,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,95.255466,53.423442,null,47.0187,36.634,null,"N.Ob/BS(/mm)",0.0002,97.65,63.28,-34.37,5.895,5.83,10]
[null,115.399473,74.200352,null,51.0654,21.2425,null,"OS/BS(%)",0.0024,50.61,28.58,-22.03,5.47,4.027,10]
[null,101.310183,70.26611,null,70.5929,31.6063]
[null,94.893357,70.264399,null,44.164,33.7791]
[]
[]
[]
[]
["Figure 4D"]
[null,"Ad.V/TV(%)",null,null,"Test details"]
[null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,0.3658,1.6064]
[null,0.6549,2.5799,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,0.1722,1.1042,null,"Ad.V/TV(%)",1E-4,0.4745,1.741,1.266,0.2141,5.916,10]
[null,0.4785,1.6576]
[null,0.7768,1.6882]
[null,0.3987,1.8093]
[]
[]
[]
[]
["Figure 4F"]
[null,"MS/BS(%)",null,null,"MAR(μm/d)",null,null,"BFR/BS(μm3/μm2/d)",null,null,"Test details"]
[null,"WT","DTAhet",null,"WT","DTAhet",null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,44.6901,35.5988,null,1.218431,0.987809,null,0.534974,0.351648]
[null,46.0109,36.3031,null,1.649988,1.041343,null,1.250553,0.465377,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,75.7916,43.8478,null,1.748986,0.914826,null,1.657635,0.401131,null,"MS/BS(%)",0.0442,57.33,37.85,-19.48,7.677,2.538,6]
[null,62.8277,35.6425,null,1.358069,1.162713,null,0.853244,0.434279,null,"MAR(μm/d)",0.0132,1.494,1.027,-0.4672,0.1343,3.478,6]
[{"$nulls":10},"BFR/BS(μm3/μm2/d)",0.0355,1.074,0.4131,-0.661,0.2446,2.702,6]
[]
[]
[]
["Figure 4G"]
[null,"P1NP(ng/mL)",null,null,"Test details"]
[null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,63.23,40.58]
[null,50.94,61.67,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,78.93,40.01,null,"P1NP(ng/mL)",0.0061,73.12,50.6,-22.52,6.653,3.385,11]
[null,82.72,38.18]
[null,79.6,61.96]
[null,83.29,51.54]
[null,null,60.23]
[]
[]
[]
[]
["Figure 4J"]
[null,"Fold change",{"$nulls":7},"Test details"]
[null,"Gene name","WT",null,null,"DTAhet",{"$nulls":3},"Test name","Multiple t tests"]
[null,"Alpl",1.17789342,1.25047308,0.67892165,0.10551756,0.04040579,0.00731336]
[null,"Bglap",0.82680499,1.76184988,0.68648019,0.06282659,0.0283082,4.04821E-3,null,"Gene name","Discovery?","P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df","q value"]
[null,"Col1a1",1.16772886,1.20667264,0.70968973,0.1576932,0.03660857,0.00967603,null,"Alpl","No",0.005647,1.036,0.05108,0.9847,0.1819,5.412,4,0.011618]
[null,"Spp1",1.28352227,1.03845977,0.75025157,0.24759539,0.09230121,0.02527378,null,"Bglap","No",0.034962,1.092,0.03173,1.06,0.3379,3.137,4,0.042374]
[null,"Sp7",1.05949859,1.65720453,0.56953905,0.36132617,0.22843422,0.28681804,null,"Col1a1","No",0.004434,1.028,0.06799,0.96,0.1659,5.786,4,0.011618]
[null,"Runx2",1.23062141,1.25916383,0.645347,0.17334402,0.05225819,7.30089E-3,null,"Spp1","No",0.005752,1.024,0.1217,0.9024,0.1676,5.384,4,0.011618]
[{"$nulls":9},"Sp7","No",0.064314,1.095,0.2922,0.8032,0.3168,2.535,4,0.064957]
[{"$nulls":9},"Runx2","No",0.009346,1.045,0.07763,0.9674,0.2061,4.695,4,0.01416]
[]
[]
["Figure 4L"]
[null,"Oc.S/BS(%)",null,null,"N. Oc/BS(/mm)",null,null,"Test details"]
[null,"WT","DTAhet",null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,21.73,46.4387,null,8.634381,24.788235]
[null,10.3638,57.798,null,4.768369,18.468837,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,8.6461,46.3141,null,3.315796,17.486352,null,"Oc.S/BS(%)",0.0013,18.32,44.61,26.29,5.92,4.441,10]
[null,24.6411,57.5221,null,7.948999,26.093711,null,"N. Oc/BS(/mm)",2E-3,6.686,18.18,11.49,2.781,4.131,10]
[null,19.1187,31.5225,null,6.990879,11.999415]
[null,25.4314,28.0746,null,8.45701,10.220669]
[]
[]
[]
[]
["Figure 4M"]
[null,"RANKL(ng/mL)",null,null,"OPG(ng/mL)",null,null,"RANKL/OPG",null,null,"Test details"]
[null,"WT","DTAhet",null,"WT","DTAhet",null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,90.87,89.46,null,838.46,810.55,null,0.110079,0.110369]
[null,89.41,106.16,null,920.85,705.33,null,0.116387,0.158498,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,81.35,119.71,null,609.95,539.2,null,0.106638,0.209283,null,"RANKL(ng/mL)",0.008,92.76,109.2,16.47,5.1,3.229,11]
[null,99.49,104.12,null,791,677.86,null,0.088345,0.194778,null,"OPG(ng/mL)",0.0259,803.3,652.7,-150.6,58.51,2.574,11]
[null,98.37,112.79,null,825.48,714.43,null,0.163105,0.193104,null,"RANKL/OPG",0.0075,0.1182,0.1716,0.05344,0.01637,3.264,11]
[null,97.08,120.56,null,834.14,507.26,null,0.12436,0.166388]
[null,null,111.79,null,null,614.58,null,null,0.168744]
[]
[]
[]
[]
["Figure 4N"]
[null,"CTX(ng/mL)",null,null,"Test details"]
[null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,3.54,3.39]
[null,3.07,4,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,2.24,4.09,null,"CTX(ng/mL)",0.0068,2.452,3.619,1.167,0.3511,3.324,11]
[null,1.81,3.74]
[null,1.94,4.01]
[null,2.11,3.66]
[null,null,2.44]
[]
[]
[]
[]
["Figure 4P"]
[null,"TRAP+ MNCs (number/well)",null,null,"Test details"]
[null,"WT","DTAhet",null,"Test name","Unpaired t test"]
[null,11,45]
[null,22,42,null,null,"P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df"]
[null,18,41,null,"TRAP+ MNCs (number/well)",0.0017,17,42.67,25.67,3.432,7.479,4]
[]
[]
[]
[]
["Figure 4Q"]
[null,"Fold change",{"$nulls":7},"Test details"]
[null,"Gene name","WT",null,null,"DTAhet",{"$nulls":3},"Test name","Multiple t tests"]
[null,"Acp5",1.013824,0.943952,1.044931,2.792494,2.045181,2.113952]
[null,"Calcr",1.022578,0.934064,1.046952,2.749241,2.155785,2.171424,null,"Gene name","Discovery?","P value","Mean of WT","Mean of DTAhet","Difference","SE of difference","t ratio","df","q value"]
[null,"Ocstamp",1.027302,0.946616,1.028319,2.048115,1.559951,1.613618,null,"Acp5","No",0.005409,1.001,2.317,-1.316,0.2403,5.477,4,0.013352]
[null,"Atp6v0d2",1.026044,0.935286,1.042052,2.384461,1.686875,1.841729,null,"Calcr","No",0.00238,1.001,2.359,-1.358,0.1983,6.848,4,0.012019]
[null,"Tyrobp",1.011055,0.933528,1.059493,1.9761,1.411571,1.388677,null,"Ocstamp","No",0.009206,1.001,1.741,-0.7398,0.1569,4.715,4,0.013352]
[{"$nulls":9},"Atp6v0d2","No",0.010576,1.001,1.971,-0.9699,0.2141,4.53,4,0.013352]
[{"$nulls":9},"Tyrobp","No",0.039141,1.001,1.592,-0.5908,0.1956,3.021,4,0.039532]