Published September 25, 2022 | Version v1
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EXCRETORY FUNCTION OF THE LIVER OF FISH AS AN INDICATOR OF ANTHROPOGENIC CHEMICAL POLLUTION OF WATER BODIES

  • 1. T.H.Shevchenko National University "Chernihiv Colehium", Chernihiv, Ukraine

Description

The results of the study of the excretory function of the liver in the detoxification of exogenous toxins of the aquatic environment are considered in the article. The ratios of the main pigment fractions of the carp gallbladder of different age groups were determined under the conditions of toxicant action of different chemical composition.

Аrticle's purpose. To show the presence of fish in an environment with high concentrations of toxic substances (herbicides and phosphates) affects the liver excretory function and can serve as an indicator of chemical anthropogenic contamination of water bodies.

Methodology. Biotesting, ichthyotoxicological experiment, physiological and biochemical method, thin-layer chromatography, densitometry, statistical methods of processing results.

Scientific novelty is to determine changes in the ratio of pigment constituents of bile in response to anthropogenic contamination of reservoirs with toxicants of different chemical structure

Conclusions. In conditions of exogenous toxicosis, which was caused by different concentrations of chemicals of different chemical composition, namely herbicides and phosphate- containing substances on fish of different ages, we observed a significant decrease in the content of dominant fractions and the total amount of bile pigments in bile. These changes can be caused by the corresponding qualitative and quantitative changes in the course of their biosynthesis, conjugation in hepatocytes and translocation through the canalicular membranes. But, at the same time, there was an increase in the content of individual pigment fractions in the gallbladder, in particular biliverdin monoglucuronide and carbohydrate compounds of this substance, which may indicate activation in the liver and the reticulo-endothelial system of alternative detoxifying mechanisms in conditions of toxicosis. The established changes in the excretory function of the liver can be used as one of the indicators of chemical anthropogenic pollution of reservoirs.

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