Published September 10, 2022 | Version v1
Journal article Open

Macrodactyly- A case report

  • 1. Unit head, Unit-3, MS, Mch PMCH PATNA, India
  • 2. DNB, FIAGES, Mch resident PMCH PATNA, India
  • 3. Mch resident PMCH PATNA, India
  • 4. Assi. Prof ASMC, Sahajanpur UP, India


Macrodactyly is a rare non-hereditary congenital anomaly of finger and toes and it is very difficult to treat this, as it largely depends on exposure of surgeon to the disease process. The disease process may be static or progressive. It accounts for about 1% of upper extremity congenital anomalies. Usually involve fibrofatty tissue and sometimes bones. The first detail study was done by Barsky in 1967. It is linked with mutation in the PIK3CA gene which control cell proliferation and migration. Barsky defined it as an increase in size of all the elements or structures within a digit or digits1. Kelikian coined the term “Nerve territory-oriented macrodactyly” due to involvement of area along the digital nerve2. This is an isolated case as no other deformity is present to group it under congenital deformity syndrome.



Files (1.0 MB)

Name Size Download all
1.0 MB Preview Download

Additional details


  • Gumy LF, Bampton ET, Tolkovsky AM. Hyperglycaemia inhibits Schwann cell proliferation and migration and restricts regeneration of axons and Schwann cells from adult murine DRG. Molecular and Cellular Neuroscience. 2008 Feb 1;37(2):298-311.
  • Cerrato F, Eberlin KR, Waters P, Upton J, Taghinia A, Labow BI. Presentation and treatment of macrodactyly in children. The Journal of hand surgery. 2013 Nov 1;38(11):2112-23.
  • Wu J, Tian G, Ji Y, Higgins JP, Lee WA. Clinical characteristics of 90 macrodactyly cases. The Journal of hand surgery. 2020 Oct 1;45(10):982-e1.
  • Richards A, Dafydd H. Key notes on plastic surgery. John Wiley & Sons; 2014 Oct 23.