R package for functional interrogation of genesets in the context of cancer

Database of molecular biology prior knowledge: gene regulatory interactions, enzyme-PTM relationships, protein complexes, protein annotations etc.

Gene set resource containing signed transcription factor (TF) - target interactions

R package used to calculate enrichment of tissue-specific genes in a set of input genes

Crossmapped phenotype ontologies for the oncology domain

High quality reference gene annotation and experimental validation

The Cancer Genome Atlas - Tumor gene expression and somatic DNA aberrations

Comprehensive resource of protein sequence and functional information

Manually curated resource of signal transduction pathways in humans

A database of biological pathways maintained by and for the scientific community

Molecular Signatures Database - collection of annotated gene sets

Manually curated and peer-reviewed pathway database

A manually curated database of literature-supported ligand-receptor interactions in human and mouse

Knowledgebase that contains the largest structural source of information on the functions of genes

Collection of manually drawn pathway maps representing our knowledge on the molecular interaction, reaction and relation networks

Literature-mined database of tumor suppressor genes/proto-oncogenes

Network of cancer genes - a web resource to analyze duplicability, orthology and network properties of cancer genes

Knowledge resource on human proteins in relation to tissue/cell type specificity and cancer prognosis

Ongoing effort to build a comprehensive public resource to study tissue-specific gene expression and regulation

Database with systematic genome-scale CRISPR/Cas9 drop-out screens in a large number of highly-annotated cancer models

Comprehensive and robust data integration for target-disease associations