Pretrained nucleAIzer models for microscopy datasets
Description
This upload consists of 4 models trained using the nucleAIzer algorithm (Hollandi et al. & https://github.com/spreka/biomagdsb) for segmenting the following microscopy image types (profiles):
- general nucleus
- fluorescent nucleus
- tiny&clumped fluorescent nucleus
- tissue nucleus
- fluorescent cytoplasm
- tissue nucleus IHC
- tissue nucleus H&E
Models for each type:
- mask_rcnn_general.h5
- mask_rcnn_general.h5
- mask_rcnn_general.h5
- mask_rcnn_general.h5
- mask_rcnn_cytoplasm.h5
- mask_rcnn_tissue_bluebrown.h5
- mask_rcnn_tissue_pink.h5
The above models were trained on resized images such that the median nuclei diameter is 40 pixels.
Additionally, a presegmentation model is also attached (mask_rcnn_presegmentation.h5) for generating the weak labels on the test set (first step in the training pipeline), while the mask_rcnn_fluo_simple.h5 is a general model that can be used for automatic object size estimation.
We additionally attach a profiles.json file describing the parameters for the models for the above segmentation tasks that can be loaded by our prediction and training code used in the napari nucleAIzer plugin (https://pypi.org/project/napari-nucleaizer/ and https://pypi.org/project/nucleaizer-backend/).
If you use our models in your research work, please cite our original paper (Hollandi et al.: nucleAIzer: a parameter-free deep learning framework for nucleus segmentation using image style transfer, Cell Systems, 2020. https://doi.org/10.1016/j.cels.2020.04.003)
Files
fluorescent_cytoplasm.png
Files
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Additional details
Related works
- Is supplemented by
- Journal article: 10.1016/j.cels.2020.04.003 (DOI)