Published July 4, 2022 | Version v1
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An Artificial Metalloenzyme Based on a Copper Heteroscorpionate Enables sp3 C–H Functionalization via Intramolecular Carbene Insertion

Creators

  • 1. Department of Chemistry, University of Basel
  • 2. Department of Biomedizin, University of Basel

Description

Data underlying the figures in the publication: Rumo, C. et al. “An Artificial Metalloenzyme Based on a Copper Heteroscorpionate Enables Sp3 C–H Functionalization Via Intramolecular Carbene Insertion” J. Am. Chem. Soc. 2022, https://doi.org/10.1021/jacs.2c03311

TOC

  1. Table_1.xlsx Source data for Table 1
  2. Figure_2_Relative_contribution.xlsx Source data for Figure 2
  3. Figure_S6_CD_titration.xlsx Source data for Figure S6
  4. Table_S2_Double_saturation.xlsx Source data for Table S2
  5. Table_S3_Complementary_data_of_selected_Sav_mutants.xlsx Source data for Table S3
  6. Table_S4_Substrate_scope.xlsx Source data for Table S4

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Additional details

Related works

Cites
Journal article: 10.1021/jacs.2c03311 (DOI)

Funding

European Commission
DrEAM – Directed Evolution of Artificial Metalloenzymes for In Vivo Applications 694424
Swiss National Science Foundation
NCCR Catalysis (phase I) 51NF40_180544