Screening of 2694 RdRP virtual screening hits in RdRP/Nsp7/Nsp8 biochemical assay and confirmation in cellular SARS-CoV-2 assay
- 1. Janssen Pharmaceutica NV
This report describes the most relevant results of virtually screening the Janssen Pharmaceutica compound collection for potential activity against SARS-CoV-2 RNA polymerase and confirmation of potential hits in a biochemical SARS-CoV RTC assay and A549-hACE2 cell-based anti-SARS-CoV-2 assay.
Screening of 2694 RdRP virtual screening hits in RdRP_Nsp7_Nsp8 biochemical assay and confirmation in cellular SARS-CoV-2 assay.xlsxmd5:4d1f9a568b4945a4686beb4858f3ebcb