Published February 11, 2021 | Version v1
Project deliverable Open

AESI Case Definition Companion Guide: Acute Disseminated Encephalomyelitis


  • 1. SPEAC


  • 1. SPEAC


This document collates into a single document all SPEAC Acute ADEM resources (Risk factors, background rates, ICD9/10-CM & MedDRA codes), tools (data abstraction & interpretation form, tabular summary of key case definition criteria and algorithm for level of certainty determination, pictorial level of certainty algorithm) and guidance (real time investigation, data collection, analysis and presentation). This guide can be used by stakeholders to assess the occurrence of Acute Disseminated Encephalomyelitis (ADEM) in several settings including as an adverse event following immunization.


The SPEAC project is funded in whole by CEPI.


SPEAC_D2.5.2.1_ADEM Case Definition Companion Guide_V1.0_format.pdf

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