"Anatomical Structures, Cell Types and Biomarkers Table for Non-FL rLN1",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
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Author Name(s):,Andrea J. Radtke,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
Author ORCID(s):,0000-0003-4379-8967,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
Reviewer(s):,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
General Publication(s):,"Anatomical structures, cell types and biomarkers of the Human Reference Atlas",,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
Data DOI:,https://doi.org/10.1038/s41556-021-00788-6,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
Date:,5/8/2022,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
Version Number:,v1.1,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
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AS/1,AS/1/LABEL,AS/1/ID,AS/2,AS/2/LABEL,AS/2/ID,AS/3,AS/3/LABEL,AS/3/ID,AS/3/NOTES,AS/4,AS/4/LABEL,AS/4/ID,AS/4/NOTES,AS/5,AS/5/LABEL,AS/5/ID,CT/1,CT/1/LABEL,CT/1/ID,CT/1/NOTES,"All Protein Biomarkers from Antibody Based Assays (IHC, FACS)","Transcriptomics/With References (Bulk, scRNA-seq)",BGene/1,BGene/1/LABEL,BGene/1/ID,BGene/2,BGene/2/LABEL,BGene/2/ID,BGene/3,BGene/3/LABEL,BGene/3/ID,BGene/4,BGene/4/LABEL,BGene/4/ID,BGene/5,BGene/5/LABEL,BGene/5/ID,BGene/6,BGene/6/LABEL,BGene/6/ID,BGene/7,BGene/7/LABEL,BGene/7/ID,BGene/8,BGene/8/LABEL,BGene/8/ID,BGene/9,BGene/9/LABEL,BGene/9/ID,BGene/10,BGene/10/LABEL,BGene/10/ID,BGene/11,BGene/11/LABEL,BGene/11/ID,BGene/12,BGene/12/LABEL,BGene/12/ID,BGene/13,BGene/13/LABEL,BGene/13/ID,BGene/14,BGene/14/LABEL,BGene/14/ID,BGene/15,BGene/15/LABEL,BGene/15/ID,BGene/16,BGene/16/LABEL,BGene/16/ID,BGene/17,BGene/17/LABEL,BGene/17/ID,BGene/18,BGene/18/LABEL,BGene/18/ID,BGene/19,BGene/19/LABEL,BGene/19/ID,BGene/20,BGene/20/LABEL,BGene/20/ID,BGene/21,BGene/21/LABEL,BGene/21/ID,BGene/22,BGene/22/LABEL,BGene/22/ID,BGene/23,BGene/23/LABEL,BGene/23/ID,BGene/24,BGene/24/LABEL,BGene/24/ID,BGene/25,BGene/25/LABEL,BGene/25/ID,BGene/26,BGene/26/LABEL,BGene/26/ID,BGene/27,BGene/27/LABEL,BGene/27/ID,BGene/28,BGene/28/LABEL,BGene/28/ID,BGene/29,BGene/29/LABEL,BGene/29/ID,BProtein/1,BProtein/1/LABEL,BProtein/1/ID,BProtein/2,BProtein/2/LABEL,BProtein/2/ID,BProtein/3,BProtein/3/LABEL,BProtein/3/ID,BProtein/4,BProtein/4/LABEL,BProtein/4/ID,BProtein/5,BProtein/5/LABEL,BProtein/5/ID,BProtein/6,BProtein/6/LABEL,BProtein/6/ID,BProtein/7,BProtein/7/LABEL,BProtein/7/ID,BProtein/8,BProtein/8/LABEL,BProtein/8/ID,BProtein/9,BProtein/9/LABEL,BProtein/9/ID,BProtein/10,BProtein/10/LABEL,BProtein/10/ID,BProtein/11,BProtein/11/LABEL,BProtein/11/ID,BProtein/12,BProtein/12/LABEL,BProtein/12/ID,BProtein/13,BProtein/13/LABEL,BProtein/13/ID,BProtein/14,BProtein/14/LABEL,BProtein/14/ID,BProtein/15,BProtein/15/LABEL,BProtein/15/ID,BProtein/16,BProtein/16/LABEL,BProtein/16/ID
lymph node,lymph node,UBERON:0000029,Capsule,capsule of lymph node,UBERON:0002194,,,,,,,,,,,,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Capsule,capsule of lymph node,UBERON:0002194,,,,,,,,,,,,aSMA+ Fibroblast,myofibroblast cell,CL:0000186,,"CD39+, CD49a+, Collagen IV+, Desmin+/-, Lumican+, Smooth Muscle Actin+, Vimentin +/-","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,CD49a+,ITGA1,HGNC:6134,Collagen IV+,COL4A2,HGNC:2203,Desmin+,DES,HGNC:2770,Lumican+,Lumican+,HGNC:6724,Smooth Muscle Actin+,ACTA2,HGNC:130,Vimentin +,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Trabeculae,trabecula of lymph node,UBERON:0002195,,,,,,,,,,,,aSMA+ Fibroblast,myofibroblast cell,CL:0000186,,"CD39+, CD49a+, Collagen IV+, Desmin+/-, Lumican+, Smooth Muscle Actin+, Vimentin +/-","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,CD49a+,ITGA1,HGNC:6134,Collagen IV+,COL4A2,HGNC:2203,Desmin+,DES,HGNC:2770,Lumican+,Lumican+,HGNC:6724,Smooth Muscle Actin+,ACTA2,HGNC:130,Vimentin +,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Trabeculae,trabecula of lymph node,UBERON:0002195,,,,,,,,,,,,Blood Vessel Endothelial Cell,blood vessel endothelial cell,CL:0000071,,"CD31+, CD39+, Collagen IV+","(Endothelial signature from Bulk) ANGPT2,APLN,CDH5,CLEC14A,ECSCR,EMCN,ENG,ESAM,ESM1,FLT1,HHIP,KDR,MMRN1,MMRN2,NOS3,PECAM1,PTPRB,RASIP1,ROBO4,SELE,TEK,TIE1,VWF",ANGPT2,ANGPT2,HGNC: 485,APLN,APLN,HGNC:16665,CDH5,CDH5,HGNC: 1764,CLEC14A,CLEC14A,HGNC: 19832,ECSCR,ECSCR,HGNC: 35454,EMCN,EMCN,HGNC: 16041,ENG,ENG,HGNC: 3349,ESAM,ESAM,HGNC: 17474,ESM1,ESM1,HGNC: 3466,FLT1,FLT1,HGNC: 3763,HHIP,HHIP,HGNC: 14866,KDR,KDR,HGNC: 6307,MMRN1,MMRN1,HGNC: 7178,MMRN2,MMRN2,HGNC: 19888,NOS3,NOS3,HGNC: 7876,PECAM1,PECAM1,HGNC: 8823,PTPRB,PTPRB,HGNC: 9665,RASIP1,RASIP1,HGNC: 24716,ROBO4,ROBO4,HGNC: 17985,SELE,SELE,HGNC: 10718,TEK,TEK,HGNC: 11724,TIE1,TIE1,HGNC: 11809,VWF,VWF,HGNC: 12726,,,,,,,,,,,,,,,,,,,CD31+,PECAM1,HGNC:8823,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,"Macrophage (CD11c+,CD163+)",,,,"CD11c+, CD163+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD163+,CD163,HGNC:1631,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,"Macrophage (CD11c+,DC-SIGN+)",,,,"CD11c+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,"Macrophage (CD163+,DC-SIGN+)",,,,"CD163+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD163+,CD163,HGNC:1631,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,Fibroblast/a-SMA fibroblast (SCS),,,,"CD39+, CD49a+, Collagen IV+, Lumican+, Vimentin +","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,CD49a+,ITGA1,HGNC:6134,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,Vimentin+,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Subcapsular Sinus,subcapsular sinus of lymph node,UBERON:0005463,,,,,,,,,,,,Lymphatic Endothelial Cell,endothelial cell of lymphatic vessel,CL:0002138,,"Collagen IV+, Lyve-1+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lyve-1+,LYVE1,HGNC:14687,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,,,,,,,,,,,,Blood Vessel Endothelial Cell,blood vessel endothelial cell,CL:0000071,,"CD31+, CD39+, Collagen IV+","(Endothelial signature from Bulk) ANGPT2,APLN,CDH5,CLEC14A,ECSCR,EMCN,ENG,ESAM,ESM1,FLT1,HHIP,KDR,MMRN1,MMRN2,NOS3,PECAM1,PTPRB,RASIP1,ROBO4,SELE,TEK,TIE1,VWF",ANGPT2,ANGPT2,HGNC: 485,APLN,APLN,HGNC:16665,CDH5,CDH5,HGNC: 1764,CLEC14A,CLEC14A,HGNC: 19832,ECSCR,ECSCR,HGNC: 35454,EMCN,EMCN,HGNC: 16041,ENG,ENG,HGNC: 3349,ESAM,ESAM,HGNC: 17474,ESM1,ESM1,HGNC: 3466,FLT1,FLT1,HGNC: 3763,HHIP,HHIP,HGNC: 14866,KDR,KDR,HGNC: 6307,MMRN1,MMRN1,HGNC: 7178,MMRN2,MMRN2,HGNC: 19888,NOS3,NOS3,HGNC: 7876,PECAM1,PECAM1,HGNC: 8823,PTPRB,PTPRB,HGNC: 9665,RASIP1,RASIP1,HGNC: 24716,ROBO4,ROBO4,HGNC: 17985,SELE,SELE,HGNC: 10718,TEK,TEK,HGNC: 11724,TIE1,TIE1,HGNC: 11809,VWF,VWF,HGNC: 12726,,,,,,,,,,,,,,,,,,,CD31+,PECAM1,HGNC:8823,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,Follicular Dendritic Cell (CD23+),follicular dendritic cell,CL:0000442,,"CD21+, CD23+, CD35+, CXCL13+","(FDC signature from scRNA-seq) CD81, CR2, CXCL13, FCER2, FDCSP, VIM",CD81,CD81,HGNC: 1701,CR2,CR2,HGNC:2336,CXCL13,CXCL13,HGNC:10639,FCER2,FCER2,HGNC: 3612,FDCSP,FDCSP,HGNC: 19215,VIM,VIM,HGNC: 12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD21+,CR2,HGNC:2336,CD23+,FCER2,HGNC:3612,CD35+,CR1,HGNC:2334,CXCL13+,CXCL13,HGNC:10639,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,BCL6+Ki-67+ B cell,,,,"BCL6+, CD20+, CD45+, HLA-DR+, Ki-67+","(Cycling B cell signature scRNA-seq) AICDA, BCL6, CD19, CD81, GMDS, ITGAE, MK167, MME, MS4A1, UBE2C, VIM",AICDA,AICDA,HGNC:13203,BCL6,BCL6,HGNC:1001,CD19,CD19,HGNC: 1633,CD81,CD81,HGNC: 1701,GMDS,GMDS,HGNC: 4369,ITGAE,ITGAE,HGNC: 6147,MK167,MKI67,HGNC: 7107,MME,MME,HGNC: 7154,MS4A1,MS4A1,HGNC: 7315,UBE2C,UBE2C,HGNC: 15937,VIM,VIM,HGNC: 12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BCL6+,BCL6,HGNC:1001,CD20+,MS4A1,HGNC:7315,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,Ki-67+,MKI67,HGNC:7107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,IRF4+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IRF4+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,Plasma cell,plasma cell,CL:0000786,,"CD138+, IRF4+","(PC signature from scRNA-seq) CD19, CD27, IRF4, JCHAIN, MZB1, SDC1, XBP1",CD19,CD19,HGNC: 1633,CD27,CD27,HGNC: 11922,IRF4,IRF4,HGNC: 6119,JCHAIN,JCHAIN,HGNC: 5713,MZB1,MZB1,HGNC: 30125,SDC1,SDC1,HGNC:10658,XBP1,XBP1,HGNC: 12801,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD138+,SDC1,HGNC:10658,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,Fibroblast/a-SMA fibroblast (Follicle),,,,"CD39+, Collagen IV+, CXCL13+, Vimentin +","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,CXCL13+,CXCL13,HGNC:10639,Vimentin+,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,"T Follicular Helper Cell (CD3+, CD4+, ICOS+, PD-1+)",,,,"CD3+, CD4+, ICOS+, PD-1+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,ICOS+,ICOS,HGNC:5351,PD-1+,PDCD1,HGNC:8760,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,"T Follicular Helper Cell (CD3+, CD4+, CD69+, ICOS+, PD-1+)",T follicular helper cell,CL:0002038,,"CD3+, CD4+, CD69+, ICOS+, PD-1+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD69+,CD69,HGNC:1694,ICOS+,ICOS,HGNC:5351,PD-1+,PDCD1,HGNC:8760,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,"T Follicular Helper Cell (CD3+, CD4+)",,,,"CD3+, CD4+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,"Tingible Body Macrophage (CD11c+, CD68+, SPARC+)",lymph node tingible body macrophage,CL:0000888,,"CD11c+, CD68+, SPARC+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD68+,CD68,HGNC:1693,SPARC+,SPARC,HGNC:11219,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,"Tingible Body Macrophage (CD11c+, CD68+)",,,,"CD11c+, CD68+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD68+,CD68,HGNC:1693,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Light Zone,lymph node germinal center light zone,UBERON:8410052,CD20+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IgD+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IgD+,IGHD,HGNC:5480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,CD20+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IgD+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IgD+,IGHD,HGNC:5480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,Plasma cell,plasma cell,CL:0000786,,"CD138+, IRF4+","(PC signature from scRNA-seq) CD19, CD27, IRF4, JCHAIN, MZB1, SDC1, XBP1",CD19,CD19,HGNC: 1633,CD27,CD27,HGNC: 11922,IRF4,IRF4,HGNC: 6119,JCHAIN,JCHAIN,HGNC: 5713,MZB1,MZB1,HGNC: 30125,SDC1,SDC1,HGNC:10658,XBP1,XBP1,HGNC: 12801,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD138+,SDC1,HGNC:10658,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,BCL6+Ki-67+ B cell,,,,"BCL6+, CD20+, CD45+, HLA-DR+, Ki-67+","(Cycling B cell signature scRNA-seq) AICDA, BCL6, CD19, CD81, GMDS, ITGAE, MK167, MME, MS4A1, UBE2C, VIM",AICDA,AICDA,HGNC:13203,BCL6,BCL6,HGNC:1001,CD19,CD19,HGNC: 1633,CD81,CD81,HGNC: 1701,GMDS,GMDS,HGNC: 4369,ITGAE,ITGAE,HGNC: 6147,MK167,MKI67,HGNC: 7107,MME,MME,HGNC: 7154,MS4A1,MS4A1,HGNC: 7315,UBE2C,UBE2C,HGNC: 15937,VIM,VIM,HGNC: 12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BCL6+,BCL6,HGNC:1001,CD20+,MS4A1,HGNC:7315,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,Ki-67+,MKI67,HGNC:7107,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,IRF4+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IRF4+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,Follicular Dendritic Cell,,,,"CD21+, CD35+, CXCL13+","(FDC signature from scRNA-seq) CD81, CR2, CXCL13, FCER2, FDCSP, VIM",CD81,CD81,HGNC: 1701,CR2,CR2,HGNC:2336,CXCL13,CXCL13,HGNC:10639,FCER2,FCER2,HGNC: 3612,FDCSP,FDCSP,HGNC: 19215,VIM,VIM,HGNC: 12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD21+,CR2,HGNC:2336,CD35+,CR1,HGNC:2334,CXCL13+,CXCL13,HGNC:10639,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,Fibroblast/a-SMA fibroblast (Follicle),,,,"CD39+, Collagen IV+, CXCL13+, Vimentin +","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,CXCL13+,CXCL13,HGNC:10639,Vimentin+,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,"Tingible Body Macrophage (CD11c+, CD68+, SPARC+)",lymph node tingible body macrophage,CL:0000888,,"CD11c+, CD68+, SPARC+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD68+,CD68,HGNC:1693,SPARC+,SPARC,HGNC:11219,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,"Tingible Body Macrophage (CD11c+, CD68+)",,,,"CD11c+, CD68+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD68+,CD68,HGNC:1693,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,"T Follicular Helper Cell (CD3+, CD4+, ICOS+, PD-1+)",,,,"CD3+, CD4+, ICOS+, PD-1+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,ICOS+,ICOS,HGNC:5351,PD-1+,PDCD1,HGNC:8760,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,"T Follicular Helper Cell (CD3+, CD4+)",,,,"CD3+, CD4+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Germinal Center,lymph node germinal center,UBERON:0009039,,Dark Zone,lymph node germinal center dark zone,UBERON:8410053,"T Follicular Helper Cell (CD3+, CD4+, CD69+, ICOS+, PD-1+)",T follicular helper cell,CL:0002038,,"CD3+, CD4+, CD69+, ICOS+, PD-1+","(Tfh signature scRNA-seq) BCL6, CD3D, CD3E, CD4, CD27, ICOS, PDCD1, TIGIT, TOX2, TXNIP",BCL6,BCL6,HGNC:1001,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,CD27,CD27,HGNC: 11922,ICOS,ICOS,HGNC:5351,PDCD1,PDCD1,HGNC:8760,TIGIT,TIGIT,HGNC: 26838,TOX2,TOX2,HGNC: 16095,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD69+,CD69,HGNC:1694,ICOS+,ICOS,HGNC:5351,PD-1+,PDCD1,HGNC:8760,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Secondary Follicle,lymph node secondary follicle,UBERON:0010753,,Mantle Zone,lymph node germinal center mantle zone,UBERON:0010420,,,,,BCL2+ B cell,,,,"BCL2+, CD20+, CD45+, HLA-DR+, IgD+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,BCL2+,BCL2,HGNC:990,CD20+,MS4A1,HGNC:7315,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,CD20+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IgD+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IgD+,IGHD,HGNC:5480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Plasma cell,plasma cell,CL:0000786,,"CD138+, IRF4+","(PC signature from scRNA-seq) CD19, CD27, IRF4, JCHAIN, MZB1, SDC1, XBP1",CD19,CD19,HGNC: 1633,CD27,CD27,HGNC: 11922,IRF4,IRF4,HGNC: 6119,JCHAIN,JCHAIN,HGNC: 5713,MZB1,MZB1,HGNC: 30125,SDC1,SDC1,HGNC:10658,XBP1,XBP1,HGNC: 12801,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD138+,SDC1,HGNC:10658,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Fibroblast/a-SMA fibroblast,lymph node fibroblastic reticular cell,CL:0009102,,"CD39+, CD49a+, Collagen IV+, Desmin+/-, Lumican+, Vimentin +","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,CD49a+,ITGA1,HGNC:6134,Collagen IV+,COL4A2,HGNC:2203,Desmin+,DES,HGNC:2770,Lumican+,Lumican+,HGNC:6724,Vimentin+,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,T Regulatory Cell,regulatory T cell,CL:0000815,,"CD3+, CD4+, CD25+, FOXP3+","(Treg signature scRNA-seq) CD3D, CD3E, CD4, CD27, CD44, CTLA4, FOXP3, ICOS, IKZF2, LAG3, TIGIT, TXNIP",CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC: 1678,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CTLA4,CTLA4,HGNC: 2505,FOXP3,FOXP3,HGNC: 6106,ICOS,ICOS,HGNC: 5351,IKZF2,IKZF2,HGNC: 13177,LAG3,LAG3,HGNC: 6476,TIGIT,TIGIT,HGNC: 26838,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD25+,IL2RA,HGNC:6008,FOXP3+,FOXP3,HGNC:6106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Blood Vessel Endothelial Cell,blood vessel endothelial cell,CL:0000071,,"CD31+, CD39+, Collagen IV+","(Endothelial signature from Bulk) ANGPT2,APLN,CDH5,CLEC14A,ECSCR,EMCN,ENG,ESAM,ESM1,FLT1,HHIP,KDR,MMRN1,MMRN2,NOS3,PECAM1,PTPRB,RASIP1,ROBO4,SELE,TEK,TIE1,VWF",ANGPT2,ANGPT2,HGNC: 485,APLN,APLN,HGNC:16665,CDH5,CDH5,HGNC: 1764,CLEC14A,CLEC14A,HGNC: 19832,ECSCR,ECSCR,HGNC: 35454,EMCN,EMCN,HGNC: 16041,ENG,ENG,HGNC: 3349,ESAM,ESAM,HGNC: 17474,ESM1,ESM1,HGNC: 3466,FLT1,FLT1,HGNC: 3763,HHIP,HHIP,HGNC: 14866,KDR,KDR,HGNC: 6307,MMRN1,MMRN1,HGNC: 7178,MMRN2,MMRN2,HGNC: 19888,NOS3,NOS3,HGNC: 7876,PECAM1,PECAM1,HGNC: 8823,PTPRB,PTPRB,HGNC: 9665,RASIP1,RASIP1,HGNC: 24716,ROBO4,ROBO4,HGNC: 17985,SELE,SELE,HGNC: 10718,TEK,TEK,HGNC: 11724,TIE1,TIE1,HGNC: 11809,VWF,VWF,HGNC: 12726,,,,,,,,,,,,,,,,,,,CD31+,PECAM1,HGNC:8823,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Lymphatic Endothelial Cell,endothelial cell of lymphatic vessel,CL:0002138,,"Collagen IV+, Lyve-1+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lyve-1+,LYVE1,HGNC:14687,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,CD4+ T cell,,,,"CD3+, CD4+, CD45+","(Inferred CD4+ T cell signature scRNA-seq) CD3D, CD3E, CD4",CD3D,CD3D,HGNC:1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD45+,PTPRC,HGNC:9666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,CD8+ T cell (Cytoxic),,,,"CD3+, CD8+, CD45+","(Cytotoxic CD8+ T cell signature scRNA-seq) CD3D, CD3E, CD8A, CD27, CD44, CXCR3, CXCR6, FCRL3, GZMA, NKG7, TXNIP",CD3D,CD3D,HGNC:1673,CD3E,CD3E,HGNC: 1674,CD8A,CD8A,HGNC:1706,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CXCR3,CXCR3,HGNC: 4540,CXCR6,CXCR6,HGNC: 16647,FCRL3,FCRL3,HGNC: 18506,GZMA,GZMA,HGNC: 4708,NKG7,NKG7,HGNC: 7830,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD8+,CD8A,HGNC:1706,CD45+,PTPRC,HGNC:9666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,CD69+ ICOS+ PD-1+ CD8+ T cell,,,,"CD3+, CD8+, CD45+, CD69+, ICOS+, PD-1+",(Exhauted CD8+ T cell signature from scRNA-seq),CADM1,CADM1,HGNC: 5951,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD8A,CD8A,HGNC:1706,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CD81,CD81,HGNC: 1701,CXCR3,CXCR3,HGNC: 4540,CXCR6,CXCR6,HGNC: 16647,FCRL3,FCRL3,HGNC: 18506,GZMA,GZMA,HGNC: 4708,HAVCR2,HAVCR2,HGNC: 18457,IFNG,IFNG,HGNC: 5438,ITGAE,ITGAE,HGNC: 6147,LAG3,LAG3,HGNC: 6476,NKG7,NKG7,HGNC: 7830,PRF1,PRF1,HGNC: 9360,TIGIT,TIGIT,HGNC: 26838,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD8+,CD8A,HGNC:1706,CD45+,PTPRC,HGNC:9666,CD69+,CD69,HGNC:1694,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,Dendritic Cell (CD11c+),dendritic cell,CL:0000451,,CD11c+,"(cDC signature from Bulk) ANPEP, AXL, CCDC103, CD1c, CD3G, CD14, CD19, CD207, CLEC4C, CLEC9A, CLEC10A, FCER1A, FCGR3A, HLA-DRA, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IL3RA, ITGAE, ITGAX, NCAM1, PTPRC, SIGLEC6, THBD",ANPEP,ANPEP,HGNC: 500,AXL,AXL,HGNC: 905,CCDC103,CCDC103,HGNC: 32700,CD1c,CD1c,HGNC: 1636,CD3G,CD3G,HGNC: 1675,CD14,CD14,HGNC: 1628,CD19,CD19,HGNC: 1633,CD207,CD207,HGNC: 17935,CLEC4C,CLEC4C,HGNC: 13258,CLEC9A,CLEC9A,HGNC: 26705,CLEC10A,CLEC10A,HGNC: 16916,FCER1A,FCER1A,HGNC: 3609,FCGR3A,FCGR3A,HGNC: 3619,HLA-DRA,HLA-DRA,HGNC: 4947,HLA-DPA1,HLA-DPA1,HGNC: 4938,HLA-DPB1,HLA-DPB1,HGNC: 4940,HLA-DQB1,HLA-DQB1,HGNC: 4944,HLA-DRB1,HLA-DRB1,HGNC: 4948,IL3RA,IL3RA,HGNC: 6012,ITGAE,ITGAE,HGNC: 6147,ITGAX,ITGAX,HGNC: 6152,NCAM1,NCAM1,HGNC: 7656,PTPRC,PTPRC,HGNC:9666,SIGLEC6,SIGLEC6,HGNC: 10875,THBD,THBD,HGNC: 11784,,,,,,,,,,,,,CD11c+,ITGAX,HGNC:6152,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,"Macrophage (CD11c+,CD163+)",,,,"CD11c+, CD163+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD163+,CD163,HGNC:1631,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,"Macrophage (CD11c+,DC-SIGN+)",,,,"CD11c+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Interfollicular Cortex,lymph node interfollicular cortex,UBERON:8410067,,,,,,,,,"Macrophage (CD163+,DC-SIGN+)",,,,"CD163+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD163+,CD163,HGNC:1631,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,CD20+ B cell,,,,"CD20+, CD44+, CD45+, HLA-DR+, IgD+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD20+,MS4A1,HGNC:7315,CD44+,CD44,HGNC:1681,CD45+,PTPRC,HGNC:9666,HLA-DR+,CD74,HGNC:1697,IgD+,IGHD,HGNC:5480,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Plasma cell,plasma cell,CL:0000786,,"CD138+, IRF4+","(PC signature from scRNA-seq) CD19, CD27, IRF4, JCHAIN, MZB1, SDC1, XBP1",CD19,CD19,HGNC: 1633,CD27,CD27,HGNC: 11922,IRF4,IRF4,HGNC: 6119,JCHAIN,JCHAIN,HGNC: 5713,MZB1,MZB1,HGNC: 30125,SDC1,SDC1,HGNC:10658,XBP1,XBP1,HGNC: 12801,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD138+,SDC1,HGNC:10658,IRF4+,IRF4,HGNC:6119,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Fibroblast/a-SMA fibroblast,lymph node fibroblastic reticular cell,CL:0009102,,"CD39+, CD49a+, Collagen IV+, Desmin+/-, Lumican+, Vimentin +","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,CD39+,ENTPD1,HGNC:3363,CD49a+,ITGA1,HGNC:6134,Collagen IV+,COL4A2,HGNC:2203,Desmin+,DES,HGNC:2770,Lumican+,Lumican+,HGNC:6724,Vimentin+,VIM,HGNC:12692,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,T Regulatory Cell,regulatory T cell,CL:0000815,,"CD3+, CD4+, CD25+, FOXP3+","(Treg signature scRNA-seq) CD3D, CD3E, CD4, CD27, CD44, CTLA4, FOXP3, ICOS, IKZF2, LAG3, TIGIT, TXNIP",CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC: 1678,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CTLA4,CTLA4,HGNC: 2505,FOXP3,FOXP3,HGNC: 6106,ICOS,ICOS,HGNC: 5351,IKZF2,IKZF2,HGNC: 13177,LAG3,LAG3,HGNC: 6476,TIGIT,TIGIT,HGNC: 26838,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD25+,IL2RA,HGNC:6008,FOXP3+,FOXP3,HGNC:6106,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Extracellular Matrix,,,,"Collagen IV+, Lumican+","(Fibroblast signature from Bulk) ACTA2,ADAMTS2,CD248,COL16A1,COL1A1,COL1A2,COL3A1,COL4A1,COL5A1,COL6A1,COL6A2,COL6A3,FAP,FBLN2,FBN1,FGF2,LOXL1,MFAP5,PCOLCE,PDGFRA,PDGFRB,TAGLN,THBS2,THY1,VEGFC",ACTA2,ACTA2,HGNC:130,ADAMTS2,ADAMTS2,HGNC:218,CD248,CD248,HGNC: 18219,COL16A1,COL16A1,HGNC: 2193,COL1A1,COL1A1,HGNC: 2197,COL1A2,COL1A2,HGNC: 2198,COL3A1,COL3A1,HGNC: 2201,COL4A1,COL4A1,HGNC: 2202,COL5A1,COL5A1,HGNC: 2209,COL6A1,COL6A1,HGNC: 2211,COL6A2,COL6A2,HGNC: 2212,COL6A3,COL6A3,HGNC: 2213,FAP,FAP,HGNC: 3590,FBLN2,FBLN2,HGNC: 3601,FBN1,FBN1,HGNC: 3603,FGF2,FGF2,HGNC: 3676,LOXL1,LOXL1,HGNC: 6665,MFAP5,MFAP5,HGNC: 29673,PCOLCE,PCOLCE,HGNC: 8738,PDGFRA,PDGFRA,HGNC: 8803,PDGFRB,PDGFRB,HGNC: 8804,TAGLN,TAGLN,HGNC: 11553,THBS2,THBS2,HGNC: 11786,THY1,THY1,HGNC: 11801,VEGFC,VEGFC,HGNC: 12682,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lumican+,Lumican+,HGNC:6724,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Blood Vessel Endothelial Cell,blood vessel endothelial cell,CL:0000071,,"CD31+, CD39+, Collagen IV+","(Endothelial signature from Bulk) ANGPT2,APLN,CDH5,CLEC14A,ECSCR,EMCN,ENG,ESAM,ESM1,FLT1,HHIP,KDR,MMRN1,MMRN2,NOS3,PECAM1,PTPRB,RASIP1,ROBO4,SELE,TEK,TIE1,VWF",ANGPT2,ANGPT2,HGNC: 485,APLN,APLN,HGNC:16665,CDH5,CDH5,HGNC: 1764,CLEC14A,CLEC14A,HGNC: 19832,ECSCR,ECSCR,HGNC: 35454,EMCN,EMCN,HGNC: 16041,ENG,ENG,HGNC: 3349,ESAM,ESAM,HGNC: 17474,ESM1,ESM1,HGNC: 3466,FLT1,FLT1,HGNC: 3763,HHIP,HHIP,HGNC: 14866,KDR,KDR,HGNC: 6307,MMRN1,MMRN1,HGNC: 7178,MMRN2,MMRN2,HGNC: 19888,NOS3,NOS3,HGNC: 7876,PECAM1,PECAM1,HGNC: 8823,PTPRB,PTPRB,HGNC: 9665,RASIP1,RASIP1,HGNC: 24716,ROBO4,ROBO4,HGNC: 17985,SELE,SELE,HGNC: 10718,TEK,TEK,HGNC: 11724,TIE1,TIE1,HGNC: 11809,VWF,VWF,HGNC: 12726,,,,,,,,,,,,,,,,,,,CD31+,PECAM1,HGNC:8823,CD39+,ENTPD1,HGNC:3363,Collagen IV+,COL4A2,HGNC:2203,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Lymphatic Endothelial Cell,endothelial cell of lymphatic vessel,CL:0002138,,"Collagen IV+, Lyve-1+",NA from bulk and scRNA-seq,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Collagen IV+,COL4A2,HGNC:2203,Lyve-1+,LYVE1,HGNC:14687,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,CD4+ T cell,,,,"CD3+, CD4+, CD45+","(Inferred CD4+ T cell signature scRNA-seq) CD3D, CD3E, CD4",CD3D,CD3D,HGNC:1673,CD3E,CD3E,HGNC: 1674,CD4,CD4,HGNC:1678,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD4+,CD4,HGNC:1678,CD45+,PTPRC,HGNC:9666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,CD8+ T cell (Cytoxic),,,,"CD3+, CD8+, CD45+","(Cytotoxic CD8+ T cell signature scRNA-seq) CD3D, CD3E, CD8A, CD27, CD44, CXCR3, CXCR6, FCRL3, GZMA, NKG7, TXNIP",CD3D,CD3D,HGNC:1673,CD3E,CD3E,HGNC: 1674,CD8A,CD8A,HGNC:1706,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CXCR3,CXCR3,HGNC: 4540,CXCR6,CXCR6,HGNC: 16647,FCRL3,FCRL3,HGNC: 18506,GZMA,GZMA,HGNC: 4708,NKG7,NKG7,HGNC: 7830,TXNIP,TXNIP,HGNC: 16952,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD8+,CD8A,HGNC:1706,CD45+,PTPRC,HGNC:9666,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,CD69+ ICOS+ PD-1+ CD8+ T cell,,,,"CD3+, CD8+, CD45+, CD69+, ICOS+, PD-1+",(Exhauted CD8+ T cell signature from scRNA-seq),CADM1,CADM1,HGNC: 5951,CD3D,CD3D,HGNC: 1673,CD3E,CD3E,HGNC: 1674,CD8A,CD8A,HGNC:1706,CD27,CD27,HGNC: 11922,CD44,CD44,HGNC: 1681,CD81,CD81,HGNC: 1701,CXCR3,CXCR3,HGNC: 4540,CXCR6,CXCR6,HGNC: 16647,FCRL3,FCRL3,HGNC: 18506,GZMA,GZMA,HGNC: 4708,HAVCR2,HAVCR2,HGNC: 18457,IFNG,IFNG,HGNC: 5438,ITGAE,ITGAE,HGNC: 6147,LAG3,LAG3,HGNC: 6476,NKG7,NKG7,HGNC: 7830,PRF1,PRF1,HGNC: 9360,TIGIT,TIGIT,HGNC: 26838,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,CD3E+,CD3E+,HGNC:1674,CD8+,CD8A,HGNC:1706,CD45+,PTPRC,HGNC:9666,CD69+,CD69,HGNC:1694,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,Dendritic Cell (CD11c+),dendritic cell,CL:0000451,,CD11c+,"(cDC signature from Bulk) ANPEP, AXL, CCDC103, CD1c, CD3G, CD14, CD19, CD207, CLEC4C, CLEC9A, CLEC10A, FCER1A, FCGR3A, HLA-DRA, HLA-DPA1, HLA-DPB1, HLA-DQB1, HLA-DRB1, IL3RA, ITGAE, ITGAX, NCAM1, PTPRC, SIGLEC6, THBD",ANPEP,ANPEP,HGNC: 500,AXL,AXL,HGNC: 905,CCDC103,CCDC103,HGNC: 32700,CD1c,CD1c,HGNC: 1636,CD3G,CD3G,HGNC: 1675,CD14,CD14,HGNC: 1628,CD19,CD19,HGNC: 1633,CD207,CD207,HGNC: 17935,CLEC4C,CLEC4C,HGNC: 13258,CLEC9A,CLEC9A,HGNC: 26705,CLEC10A,CLEC10A,HGNC: 16916,FCER1A,FCER1A,HGNC: 3609,FCGR3A,FCGR3A,HGNC: 3619,HLA-DRA,HLA-DRA,HGNC: 4947,HLA-DPA1,HLA-DPA1,HGNC: 4938,HLA-DPB1,HLA-DPB1,HGNC: 4940,HLA-DQB1,HLA-DQB1,HGNC: 4944,HLA-DRB1,HLA-DRB1,HGNC: 4948,IL3RA,IL3RA,HGNC: 6012,ITGAE,ITGAE,HGNC: 6147,ITGAX,ITGAX,HGNC: 6152,NCAM1,NCAM1,HGNC: 7656,PTPRC,PTPRC,HGNC:9666,SIGLEC6,SIGLEC6,HGNC: 10875,THBD,THBD,HGNC: 11784,,,,,,,,,,,,,CD11c+,ITGAX,HGNC:6152,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,"Macrophage (CD11c+,CD163+)",,,,"CD11c+, CD163+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,CD163+,CD163,HGNC:1631,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,"Macrophage (CD11c+,DC-SIGN+)",,,,"CD11c+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD11c+,ITGAX,HGNC:6152,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
lymph node,lymph node,UBERON:0000029,Cortex,cortex of lymph node,UBERON:0002006,Paracortex,lymph node paracortex,UBERON:8410066,,,,,,,,,"Macrophage (CD163+,DC-SIGN+)",,,,"CD163+, DC-SIGN+","(Macrophage signature from Bulk) ADAP2,ADORA3,C1QA,C1QC,C3AR1,C5AR1,CCL7,CCR1,CD14,CD163,CD33,CD4,CD68,CLEC5A,CMKLR1,CSF1R,CYBB,FPR3,IL10,IL4I1,MRC1,MS4A4A,MSR1,PLA2G7,RAB7B,SIGLEC1,TREM2,VSIG4,MS4A7",ADAP2,ADAP2,HGNC: 16487,ADORA3,ADORA3,HGNC: 268,C1QA,C1QA,HGNC: 1241,C1QC,C1QC,HGNC: 1245,C3AR1,C3AR1,HGNC: 1319,C5AR1,C5AR1,HGNC: 1338,CCL7,CCL7,HGNC: 10634,CCR1,CCR1,HGNC: 1602,CD14,CD14,HGNC: 1628,CD163,CD163,HGNC: 1631,CD33,CD33,HGNC: 1659,CD4,CD4,HGNC: 1678,CD68,CD68,HGNC: 1693,CLEC5A,CLEC5A,HGNC: 2054,CMKLR1,CMKLR1,HGNC: 2121,CSF1R,CSF1R,HGNC: 2433,CYBB,CYBB,HGNC: 2578,FPR3,FPR3,HGNC: 3828,IL10,IL10,HGNC: 5962,IL4I1,IL4I1,HGNC: 19094,MRC1,MRC1,HGNC: 7228,MS4A4A,MS4A4A,HGNC: 13371,MSR1,MSR1,HGNC: 7376,PLA2G7,PLA2G7,HGNC: 9040,RAB7B,RAB7B,HGNC: 30513,SIGLEC1,SIGLEC1,HGNC: 11127,TREM2,TREM2,HGNC: 17761,VSIG4,VSIG4,HGNC: 17032,MS4A7,MS4A7,HGNC: 13378,CD163+,CD163,HGNC:1631,DC-SIGN+,CD209,HGNC:1641,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,