Streptomycin for Tuberculosis Dataset Codebook

Source: This data set is from a prospective, randomized, placebo-controlled clinical trial, Streptomycin Treatment of Pulmonary Tuberculosis published on October 30, 1948 in the British Medical Journal, pages 769-782, by the Streptomycin in Tuberculosis Trials Committee. This is often considered the first modern randomized clinical trial ever published.

This dataset is reconstructed from the article to the best of my ability, and particularly from tables 1-4, which can be reconstructed exactly with janitor::tabyl(), or a more modern Table 1 can be created with gtsummary::tbl_summary(). The particpant_id variable was added to this reconstructed dataset. The radnum variable and the improved variable were added to allow for multivariate and logistic regression modeling (though you can also use logistic regression for the dichotomous outcome of death, radnum =1). You can read the original study in a the BMJ here.

Codebook