Study of Formation Constants of Substituted Salicylanils and 2'-Hydroxysalicylanils

Physical Chemistry Laboratory, The Institute of Science, 15, Madam Cama Road, Bombay-400 032

Manuscript received 12 February 1983, revised 9 March 1984, accepted 17 June 1984

The proton-ligand stability constants of some substituted salicylanils l!nd 2'- hydroxysalicylanils
have been studied by the Bjerrum-Calvm pH titration technique m water dioxane medium (1: 3 v/v) at  \(\mu\)  \(\sim\)0.1 (NaCIO₄) and at 30^o (±0.1). The results have been discussed on the basis or the electrometric effects of substituent groups with regard to their nature and position in the salicylaldehyde and aniline nucleus.The proton-ligand stability constants for closely related substituted anils are round to vary in the following order in terms or their substituents. 2'-CH₃, <3'-CH₃. <4'-CH₃, and similarly 2'-chloro <3'-chloro<4'-chloro and further as propiophenone < acetophenone.