Published October 21, 2015
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Stereoselective Synthesis of C1 -C6 and C7 -C22 Fragments of (-) Callystatin A
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The stereoselective synthesis of the two major fragments (C1 -C6 and C7 -C22) of cytotoxic polyketide marine natural product (-) callystatin A, has been achieved with Sharpless epoxidation, desymmetrization strategy, Horner-Wadsworth-Emmons reaction and witting olefination.
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IJBCMB-2332-2756-03-101.pdf
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