Authors: L.T. Riemann, C.S. Aigner, S.L.R. Ellison, R. Brühl, R. Mekle, S. Schmitter, O. Speck, G. Rose, B. Ittermann, A. Fillmer
Data from the Paper: "Assessment of Measurement Precision in Single Voxel Spectroscopy at 7 T: Towards Minimal Detectable Changes of Metabolite Concentrations in the Human Brain In-Vivo"
DOI: 10.1002/mrm.29034
Journal: Magnetic Resonance in Medicine (MRM)
Publisher: Wiley

Correspondence: layla.riemann@ptb.de, ariane.fillmer@ptb.de

Code to generate the restricted maximum-likelihood estimation (REML) and the Bland-Altman (BA) plots of the spectral shape can be found under https://gitlab1.ptb.de/LRiemann/repeatability_reproducibility.git

Following data sets are provided:

1. ConcentrationsPaper-mrm29034_20211012_Riemann-Fillmer.xls

Data that is used with the R code to obtain the REML analysis of the metabolite concentrations. Note that the zeros indicate that the metabolite concentration could not be quantified.

2. RawData-mrm29034_20211012_Riemann-Fillmer.zip folder

Raw spectral data from Magnetom Siemens 7 T scanner
file names have the following structure: "SubjectNumber_Session_ScanBlock_Pulse.dat", e.g. "p1_T1_1_GOIA.dat"

3. npy-files-mrm29034_20211012_Riemann-Fillmer.zip folder

Spectral data in a python format to generate the BA plots with the shared code;
data names have the following structure: "SubjectNumber_PulseSessionScanBlock", e.g. "p1_GOIAT11.npy" for Subject p1, GOIA Pulse (AHS for hyperbolic secant), Session T1, ScanBlock 1 

4. AnonymizedVolunteerData-mrm29034_20211012_Riemann-Fillmer.xlsx

Anonymized measurement data for each individual volunteer and measurement:
age, gender, transmit voltage, linewidth, peak voltages for all three pulses (HS, GOIA, WURST), CSF -, gray and white matter fraction in the scanned voxel for each subject.