Type species (original binomen): Macrocypris sapeloensis Darby, 1965 (original designation).
Additional species (listed by original binomen): Macropyxis adrecta Maddocks, 1990; Macrocypris adriatica Breman, 1975; Macropyxis adunca Maddocks, 1990; Macropyxis amanda Maddocks, 1990; Macropyxis amoena Maddocks, 1990; Macropyxis andreseni Jellinek & Swanson, 2003; Macropyxis antonbruunae Maddocks, 1990; Macropyxis arta Maddocks, 1990; Macropyxis audens Maddocks, 1990; Macrocypris bathyalensis Hulings, 1967; Macropyxis eltaninae Maddocks, 1990; Macropyxis improcera Maddocks, 1990; Macropyxis kaesleri Maddocks, 1990; Macropyxis kalbi Maddocks, 1990; Macropyxis kornickeri Maddocks, 1990; Macropyxis labutisi Maddocks, 1990; Macrocypris longanavan den Bold, 1960; Macrocypris rhodanavan den Bold, 1960; Macrocypris similis Brady, 1880; Macropyxis simulans Maddocks, 1990; Macropyxis sonneae Jellinek & Swanson, 2003; Macropyxis steinecki Maddocks, 1990; Macrocypris tenuicauda Brady, 1880; Macropyxis thiedei Jellinek & Swanson, 2003.