model_p beta_cntot stde_cntot t_val_cntot pval_cntot beta_loh stde_loh tval_loh pval_loh gene class fdr_model fdr_loh fdr_cntot ass_coeff_CN ass_coeff_LOH 4.04839150963339e-08 204.137876762773 35.2742620202147 5.78716222739932 3.84512295338743e-08 -61.7367338588688 173.607556570037 -0.355610867859678 0.722615494685329 DPM1 other 0.000414555290586459 1 0.000456262289648953 5.78716222739932 -0.355610867859678 0.578848544763637 -16.78204897436 17.6191961635385 -0.95248664119474 0.342362420389199 -33.8379929296045 37.2119731067843 -0.909330790724326 0.364615155513264 FGR other 1 1 1 -0.95248664119474 -0.909330790724326 0.414978079029361 -172.262313060817 149.798043232162 -1.14996370676111 0.251976834675809 -527.694117647059 591.075146339784 -0.892769931056634 0.373400961847544 CFH other 1 1 1 -1.14996370676111 -0.892769931056634 1.13322798360698e-09 142.488156808287 62.9695696306343 2.26280976103365 0.0250546128670394 -519.579333058098 127.540968734475 -4.0738230092936 7.4020697150452e-05 FUCA2 other 1.27578806394474e-05 1 1 2.26280976103365 -4.0738230092936 4.59419208692325e-12 172.757253935141 27.974346574436 6.17555993579537 5.81951359023097e-09 -152.91936008236 83.5468795127999 -1.83034197056914 0.0691705364960292 GCLC other 5.71333727929776e-08 1 7.15392805647093e-05 6.17555993579537 -1.83034197056914 1.78946819311468e-43 315.025617930974 16.1938520316177 19.4534084488299 3.26166964309084e-43 -14.2921924403034 105.479248194623 -0.135497670726022 0.892396509302802 NFYA other 2.60814989146465e-39 1 4.75453583873352e-39 19.4534084488299 -0.135497670726022 2.75752724468259e-08 73.1265001500151 20.0392568661037 3.64916227376216 0.000359011743786777 -80.2625075007498 44.4404903917797 -1.80606709766633 0.0728480436315279 STPG1 other 0.000285762548366457 1 1 3.64916227376216 -1.80606709766633 3.94110392432964e-10 185.652377737774 47.9143026373821 3.87467556697634 0.000157193401216226 -248.264720222022 106.258187128045 -2.33642909720316 0.0207491038899052 NIPAL3 other 4.54369871435964e-06 1 1 3.87467556697634 -2.33642909720316 1.20036332502389e-07 77.6234198270128 25.1915991191219 3.08132165250645 0.0024819190955559 -250.221002439565 74.8369233427413 -3.34355009884082 0.00106138118061567 ENPP4 other 0.00118655914678611 1 1 3.08132165250645 -3.34355009884082 1.78954649903468e-05 413.632204093364 216.647985328147 1.90923632853937 0.0583535518035031 -1521.76825569143 469.771439733702 -3.23938010483156 0.00150817800321815 SEMA3F other 0.143933224917359 1 1 1.90923632853937 -3.23938010483156 0.730660500775256 -0.332461651305952 116.338072163775 -0.00285772013514139 0.997723694830536 -263.861801192716 353.453742322779 -0.746524281957535 0.456527050604806 CFTR other 1 1 1 -0.00285772013514139 -0.746524281957535 4.68572628141862e-09 253.673162978112 44.6950133114489 5.67564800149935 6.86014957389449e-08 -182.474740316278 137.791744009718 -1.32427919849398 0.18741130718116 ANKIB1 other 5.09666447629903e-05 1 0.000803872327068956 5.67564800149935 -1.32427919849398 0.0167648657293627 107.225848907607 57.3930206186026 1.86827331532456 0.0636615402633993 -261.236114767044 176.938853332822 -1.47642029913949 0.141913497757781 CYP51A1 other 1 1 1 1.86827331532456 -1.47642029913949 7.27025024673373e-16 199.740134043372 23.7937186015524 8.39465816118125 3.13287939365453e-14 -91.8506995768116 73.3544469432915 -1.25214902987162 0.212451552413797 KRIT1 other 9.89481058580461e-12 1 4.33057918584865e-10 8.39465816118125 -1.25214902987162 2.28644478761244e-15 71.4836283544862 9.06242104660226 7.88791736632975 8.17316999794345e-13 -63.1485383300659 37.0973426668463 -1.7022388610735 0.0909459936652001 RAD52 other 3.0848713074467e-11 1 1.11155111972031e-08 7.88791736632975 -1.7022388610735 0.100746634400916 135.243297482048 85.8161278794624 1.57596597310952 0.117212936222427 -252.97039917218 257.495833439487 -0.98242521361663 0.327526797929938 BAD other 1 1 1 1.57596597310952 -0.98242521361663 0.0306730427508097 384.284822345749 218.647330893367 1.75755551543029 0.0808631562339043 -206.965207402928 400.853439971173 -0.516311416506272 0.606397229884473 LAP3 other 1 1 1 1.75755551543029 -0.516311416506272 0.459639184211888 -4.500611995104 20.2217781026349 -0.222562623932539 0.824178691810811 -42.8321203189188 37.9885788173368 -1.12749993951792 0.261331487436216 HS3ST1 other 1 1 1 -0.222562623932539 -1.12749993951792 0.693698176559932 -122.322594889035 147.320570442983 -0.830315783608623 0.407654005976007 -208.97333570811 478.058995587046 -0.437128759498597 0.662634322070445 AOC1 other 1 1 1 -0.830315783608623 -0.437128759498597 0.175843970911288 8.95358152686145 7.11643775664731 1.25815496924681 0.210252380896434 -9.17427404515052 16.2708494017529 -0.563847271806362 0.573683611325821 HECW1 other 1 1 1 1.25815496924681 -0.563847271806362 2.71230965234518e-13 174.565377016307 32.1438574425458 5.43075383308699 2.26931828107031e-07 -72.1552888443278 62.9629258927241 -1.14599643871801 0.253658743169729 MAD1L1 other 3.50077806828193e-09 1 0.0025822572720299 5.43075383308699 -1.14599643871801 1.33814910463245e-08 1501.0917789436 235.21758671851 6.38171575469818 1.97947048383625e-09 1197.71771789675 902.540475365753 1.32705152908669 0.186468640280928 LASP1 other 0.000141669845707437 1 2.47473399889208e-05 6.38171575469818 1.32705152908669 3.60766630942818e-06 117.349493521066 22.5380583679977 5.20672595682392 6.10583249159361e-07 54.3162611248564 97.4297090864288 0.557491771597851 0.578006197986996 SNX11 other 0.0311377679166746 1 0.00676587298393488 5.20672595682392 0.557491771597851 0.796864225719068 71.9262446242845 166.119299315595 0.432979460668433 0.665639442812562 333.678067451085 539.06134859268 0.618998316837618 0.53683802785146 TMEM176A other 1 1 1 0.432979460668433 0.618998316837618 4.44674512648033e-19 642.574141992569 68.6842265387247 9.3554834111771 9.85729184548881e-17 -609.683547515994 300.05135975887 -2.03193062682986 0.0438908860875789 M6PR other 6.24856625173016e-15 1 1.39155388982766e-12 9.3554834111771 -2.03193062682986 1.59607338016108e-10 164.823896328006 41.3784104576542 3.98333078784365 0.000104804208613869 -142.626226898087 78.9606632575994 -1.80629469173513 0.0728377047077639 ICA1 other 1.87299211161903e-06 1 0.956967228853235 3.98333078784365 -1.80629469173513 1.00320327814453e-11 554.89038752734 111.789172682343 4.96372210485986 2.04899307709528e-06 -326.97878093529 195.800404514768 -1.66995968034698 0.0972444302741625 DBNDD1 other 1.2334384304787e-07 1 0.0219631567933843 4.96372210485986 -1.66995968034698 7.58491017673579e-06 102.104951512714 25.654948863746 3.97993198329864 0.000105891455127512 -107.798453769496 75.4582434296513 -1.42858419266007 0.15514885491263 ALS2 other 0.0633303268320362 1 0.965670277621204 3.97993198329864 -1.42858419266007 0.0204496834063081 -22.7797677099033 38.5440212852996 -0.591006515414918 0.555376895759719 -315.91189378491 113.394600853617 -2.78595181257992 0.00600379839976618 CASP10 other 1 1 1 -0.591006515414918 -2.78595181257992 0.00138257070217774 -27.492283147389 103.696353228152 -0.265122950726153 0.791269291870826 -1072.14830048202 303.050279976603 -3.53785616223418 0.000533430040447153 CFLAR other 1 1 1 -0.265122950726153 -3.53785616223418 0.679162080621564 13.9097822554436 17.9681984289233 0.77413338407111 0.440031099113737 38.3619475138121 58.8705283646251 0.651632464995228 0.515603324817939 TFPI other 1 1 1 0.77413338407111 0.651632464995228 6.11200934584373e-14 92.7194034660556 10.8129333380086 8.57486128580274 1.05893637458222e-14 6.09067960469781 42.690161409309 0.14267173989578 0.886738383857402 NDUFAF7 other 8.02445707015823e-10 1 1.47255692249403e-10 8.57486128580274 0.14267173989578 3.41736199528648e-06 366.198824994413 111.143814202633 3.29481966784741 0.00125805274139593 -555.24095596922 241.000116093313 -2.30390327179028 0.0227552558729741 RBM5 other 0.0295772680692045 1 1 3.29481966784741 -2.30390327179028 1.89033030248136e-15 48.2588059701493 6.44608011140724 7.48653524872404 5.21705957591064e-12 17.9505804311774 12.1746670381723 1.47442064533637 0.142423035523694 MTMR7 other 2.55515946986405e-11 1 6.99816371512653e-08 7.48653524872404 1.47442064533637 0.00148986218211946 714.851802525833 201.916827654409 3.54032801936318 0.000529754666528257 678.65857890037 381.358919468934 1.779579666959 0.0771299489036295 SLC7A2 other 1 1 1 3.54032801936318 1.779579666959 0.000247047337431538 623.101994360745 156.794308786901 3.974009000592 0.000108028492443368 -73.7438184334614 528.792451193359 -0.1394570180929 0.88927005787815 ARF5 other 1 1 0.984031537666637 3.974009000592 -0.1394570180929 2.70155662498798e-28 356.961895276267 25.6055154119691 13.9408205432728 6.37209466563812e-28 -462.721467642314 164.310322146206 -2.81614363357268 0.0055894853297797 SARM1 other 3.90969274768261e-24 1 9.23635121784246e-24 13.9408205432728 -2.81614363357268 9.14479711295048e-34 765.777445268253 48.21717062025 15.881841166073 1.33518986409856e-32 -1270.37198451184 308.583268660799 -4.11678828221973 6.67816138931059e-05 POLDIP2 other 1.32919626036735e-29 0.959451446802253 1.94096550544007e-28 15.881841166073 -4.11678828221973 0.969295860152764 18.8541406899396 147.309958195742 0.127989586860698 0.898328646504887 136.443864297588 588.273880719254 0.231939354728388 0.816901242017289 PLXND1 other 1 1 1 0.127989586860698 0.231939354728388 4.74409782631574e-07 156.670015754314 139.339241316229 1.12437827473708 0.262625078301573 -1747.27693374588 394.137853104598 -4.43316195078117 1.76982775943933e-05 AK2 other 0.00445186140021469 0.256341852677193 1 1.12437827473708 -4.43316195078117 0.00226493349939432 91.5264866576925 25.7042332709488 3.56075537025011 0.000495826278506028 99.6172867436626 48.5614089481765 2.05136730793729 0.041970758805339 CD38 other 1 1 1 3.56075537025011 2.05136730793729 5.65460402091478e-13 801.817067802379 137.571435081423 5.82836885671664 3.40990525643678e-08 -2113.73621107277 614.850237868079 -3.43780660864978 0.000763021481865888 FKBP4 other 7.23393492395628e-09 1 0.000405574131200591 5.82836885671664 -3.43780660864978 1.81961944569853e-20 1058.35105257233 124.300452288014 8.51445858073023 1.45660716041478e-14 -117.000318425243 273.204616002177 -0.428251616452594 0.669070192815945 KDM1A other 2.57639917316455e-16 1 2.02220772080385e-10 8.51445858073023 -0.428251616452594 0.00010504549846829 195.098513039616 76.6538817104775 2.54518764981147 0.0120294740260424 -360.634584462718 164.74807839964 -2.18900631780301 0.0302902118478682 RBM6 other 0.768302775797072 1 1 2.54518764981147 -2.18900631780301 2.75937284162665e-13 90.5679958723375 11.4682499913669 7.89728127138104 4.75659375834158e-13 -91.1423306552662 64.4577007275538 -1.41398668625338 0.159358384366443 CAMKK1 other 3.55986690298254e-09 1 6.49132350200875e-09 7.89728127138104 -1.41398668625338 2.11331492289546e-26 211.00278867283 17.2811916487099 12.2099675162495 2.76573275483099e-24 -194.124017579501 105.390275274014 -1.8419537957822 0.0674435585341855 RECQL other 3.05141541716875e-22 1 3.99205865832305e-20 12.2099675162495 -1.8419537957822 1.13461789716612e-14 95.9452643193945 12.8750464999305 7.45203245051675 6.46677298229851e-12 -99.0469558652391 39.9476523943852 -2.47941868742106 0.0142514211563815 VPS50 other 1.5115379626047e-10 1 8.65771566870124e-08 7.45203245051675 -2.47941868742106 0.000326952836855222 233.101203554914 67.4658702845562 3.45509814920854 0.000710882049186504 -200.710363034139 291.378582975693 -0.688830184375225 0.491966588854983 HSPB6 other 1 1 1 3.45509814920854 -0.688830184375225 0.000720760262124231 66.9327274716345 29.138674349524 2.297040924675 0.0229725746153901 -258.391449692121 129.372540391334 -1.9972665676234 0.0475692988635003 ARHGAP33 other 1 1 1 2.297040924675 -1.9972665676234 0.000471154143015292 99.5062641184345 103.656854521966 0.959958360470494 0.338561661183254 -604.073825799014 211.454254344254 -2.85675891304397 0.00486374377059281 NDUFAB1 essential 1 1 1 0.959958360470494 -2.85675891304397 0.0279216806179913 82.3285355308378 35.2284319249506 2.33699120375916 0.0207532610439514 -67.5491389822993 112.551739891719 -0.600160770924421 0.549298723622261 PDK4 other 1 1 1 2.33699120375916 -0.600160770924421 0.111007506370817 -66.1816032590013 114.377116211262 -0.578626262413885 0.563827360349182 -514.560907523142 246.223031439569 -2.08981631212445 0.0385533945098397 ZMYND10 other 1 1 1 -0.578626262413885 -2.08981631212445 3.10172232738991e-12 213.479817614904 32.2335783981746 6.62290158969733 5.63645142520467e-10 -211.272055593969 101.567733400551 -2.08010997706111 0.0391829841065439 SLC25A13 other 3.8796342870993e-08 1 7.1712571482879e-06 6.62290158969733 -2.08010997706111 5.26999990772496e-08 251.001119010006 41.0495320697618 6.11459147898302 7.46279917351484e-09 76.6281266456067 169.970527644143 0.450831845424628 0.652736749134398 CDC27 essential 0.000535273890627624 1 9.13392695289444e-05 6.11459147898302 0.450831845424628 6.31325018924055e-25 433.741625684328 34.4002730161748 12.6086681195927 3.23356578958739e-25 93.9494293402697 180.392783511853 0.520804809988958 0.603281068300408 DVL2 other 9.09171159752531e-21 1 4.67153249621691e-21 12.6086681195927 0.520804809988958 0.115788127415508 27.7492177440338 35.189128245498 0.788573605758022 0.431614130998704 -94.4779800783257 75.4075627148977 -1.25289794122547 0.212205544884908 PRSS22 other 1 1 1 0.788573605758022 -1.25289794122547 3.33100991688878e-12 876.641049281012 123.818863272603 7.08002824538113 5.39400805718415e-11 -46.5616941618574 395.099645453938 -0.117847977586418 0.906347900688743 UPF1 essential 4.15943208321902e-08 1 7.07855677344277e-07 7.08002824538113 -0.117847977586418 0.667614083660968 34.8181261498824 54.3962253243075 0.640083497380536 0.523107992486967 -17.0044712677606 114.700010293393 -0.148251697835638 0.882345929113957 SKAP2 other 1 1 1 0.640083497380536 -0.148251697835638 0.000732794828826216 -70.3421096360839 66.5686281724147 -1.05668558249234 0.292331649901637 -353.801181662081 100.817615093447 -3.50931909403078 0.000591293408158677 MCUB other 1 1 1 -1.05668558249234 -3.50931909403078 0.256430557522441 15.4708664803268 10.1906969366117 1.51813625471926 0.131157373005314 6.89275773300714 21.5629801108159 0.31965700926236 0.749688452727392 HOXA11 og 1 1 1 1.51813625471926 0.31965700926236 0.00370765727607809 242.257118274945 101.267094880252 2.39225899154522 0.0179584970182236 -485.301732404843 314.242693690736 -1.5443532726411 0.124568629776376 POLR2J essential 1 1 1 2.39225899154522 -1.5443532726411 4.85294967837898e-25 255.044991001799 20.7721098940037 12.2782419457266 1.02202424933345e-24 -143.70390467361 110.694627023504 -1.29820126358163 0.196122007732355 DHX33 essential 6.99115930667276e-21 1 1.47570081361257e-20 12.2782419457266 -1.29820126358163 0.262816440721172 0.118052278946964 63.3945667352512 0.00186218291292966 0.998516573044991 441.569374980339 270.243188207573 1.63397041719761 0.104281571625023 MEOX1 other 1 1 1 0.00186218291292966 1.63397041719761 0.0488054069684512 3.6859273670558 25.9763729635376 0.141895382093168 0.887349314031919 -87.3150670125377 49.3354438136028 -1.76982429391794 0.0787483185339827 THSD7A other 1 1 1 0.141895382093168 -1.76982429391794 2.58746302131219e-18 417.904149266464 40.6931030122779 10.2696555025645 4.03233942762136e-19 52.6710444089544 157.065274647626 0.335344935582491 0.737827279845946 LIG3 other 3.61882578160722e-14 1 5.75777746870054e-15 10.2696555025645 0.335344935582491 5.10086656673964e-17 143.282513264045 17.512813945938 8.18158142411369 1.14177583774031e-13 -140.725940838724 60.1633084629147 -2.33906585980837 0.0206602653561209 RPAP3 essential 7.03868577544403e-13 1 1.56914253380651e-09 8.18158142411369 -2.33906585980837 0.00206138740276452 318.943575755808 99.865534341927 3.19373022792613 0.00169936573144748 -33.3123583924074 274.462830770739 -0.121372931623785 0.903551853656625 ACSM3 other 1 1 1 3.19373022792613 -0.121372931623785 9.24878900558759e-09 246.156811678516 69.2520852380174 3.55450396666731 0.00050588981173697 -150.179277127994 110.923175945027 -1.35390350887918 0.177790058644855 CIAPIN1 essential 9.88325593137089e-05 1 1 3.55450396666731 -1.35390350887918 0.0136678432319622 260.620646115551 102.247113634538 2.5489291272034 0.0118675838383996 -31.2136221793324 152.745940073256 -0.204349930115083 0.83837265035721 SPPL2B other 1 1 1 2.5489291272034 -0.204349930115083 1.38163792702649e-09 69.7902933167451 14.128024565565 4.93984795913001 2.18198130653198e-06 -64.4608966911529 36.1764559635385 -1.78184664512526 0.0769266941031449 FAM214B other 1.54826346102588e-05 1 0.0233406540359726 4.93984795913001 -1.78184664512526 0.963083605933338 5.31795049162498 20.0585304445961 0.265121640207578 0.791272614786889 6.93976975146817 83.7969944989037 0.0828164517470727 0.934105736718057 COPZ2 other 1 1 1 0.265121640207578 0.0828164517470727 0.558199719926317 17.4788354766258 31.8820727646616 0.548233974799766 0.584325092642536 -70.1298645342524 101.974759434469 -0.687717871786881 0.492664958884735 PRKAR2B other 1 1 1 0.548233974799766 -0.687717871786881 1.11579307976357e-11 1469.42658051034 211.058887468683 6.96216396349752 9.59862787245283e-11 432.929050233303 435.759021333352 0.99350565114776 0.322052985361213 CREBBP og 1.37008232264169e-07 1 1.25127712945295e-06 6.96216396349752 0.99350565114776 0.0628147706165828 183.080270638466 77.2416794439773 2.37022643676789 0.0189994068300975 55.6064173890529 292.359082645185 0.190199041828772 0.849400437823895 TSPOAP1 other 1 1 1 2.37022643676789 0.190199041828772 0.399521789123592 -11.1259376963158 10.3921369187632 -1.07061115372987 0.286052592944128 -37.1852296663095 33.2019629454855 -1.11997082001941 0.264504427735881 PON1 other 1 1 1 -1.07061115372987 -1.11997082001941 9.87304968659204e-06 56.1560248224525 12.6556731541186 4.43722148467286 1.72708420675996e-05 -29.6626868347127 38.0466984995496 -0.779638917554536 0.436799966642775 CROT other 0.0816402478584296 1 0.17130948246852 4.43722148467286 -0.779638917554536 1.49076204083865e-12 859.346056377428 113.837153765746 7.54890673167911 3.59796974114525e-12 -92.1602132666324 354.377621107512 -0.260062170344195 0.795163192710977 KMT2E other 1.88283245757922e-08 1 4.83854970789213e-08 7.54890673167911 -0.260062170344195 0.00439090536659494 501.662969500501 194.738789238169 2.57608138297994 0.0109518422897132 -1012.80633015948 712.733429146272 -1.42101701525723 0.157373625657103 RHBDD2 other 1 1 1 2.57608138297994 -1.42101701525723 1.29140729053824e-05 123.418341769435 36.8866780009751 3.34587847043781 0.00103053799691544 -81.2757912740014 70.9780678175911 -1.14508317531092 0.253951162516526 IBTK other 0.105507975636974 1 1 3.34587847043781 -1.14508317531092 1.5848458278452e-06 -20.4385459972279 54.6082883529517 -0.374275528746235 0.708717536836021 -372.13186227481 85.6675038012094 -4.34390925103104 2.53767968174041e-05 ZNF195 other 0.0142065580008043 0.366923105182845 1 -0.374275528746235 -4.34390925103104 8.89123988215382e-06 293.142215431066 61.7280775225028 4.74892831911381 4.86378386125407e-06 77.0767871278929 113.190662806293 0.680946512874451 0.496991326477261 MYCBP2 other 0.0738417472212875 1 0.0507535845921862 4.74892831911381 0.680946512874451 1.11078454150047e-10 425.938210195069 78.6625677415524 5.41475090915539 2.46570540941416e-07 -283.091099946495 144.554528180607 -1.95836895259897 0.052092769037944 FBXL3 other 1.31328056341601e-06 1 0.00279882221022601 5.41475090915539 -1.95836895259897 0.387409858551515 -42.2848750153646 32.1483476568526 -1.31530476983477 0.190349900755582 -66.0580589109523 68.5740992640127 -0.963309173870829 0.336892850421572 ITGAL other 1 1 1 -1.31530476983477 -0.963309173870829 1.07287709397499e-13 656.932002495321 78.7713379711855 8.33973396180762 3.55905459039071e-14 -352.114472863378 322.480549081941 -1.09189367813284 0.276552580060529 PDK2 other 1.39817342886821e-09 1 4.91576620024765e-10 8.33973396180762 -1.09189367813284 0.000565085259211125 2246.58858124117 616.913784245923 3.64165729249713 0.00036674192816011 -3180.91160274494 2525.19790096561 -1.25966824284488 0.209646612054877 ITGA3 other 1 1 1 3.64165729249713 -1.25966824284488 0.0968613843105205 22.6309092083529 10.7505161720234 2.10509977811544 0.0368848493419099 -14.2395334459118 42.1602559020211 -0.337747794486921 0.736007308316334 ITGA2B other 1 1 1 2.10509977811544 -0.337747794486921 4.8469224266874e-07 442.660184645148 100.999093128148 4.38281345836937 2.13523062514299e-05 -146.574111744929 207.253726118248 -0.707220634775471 0.480477794741239 GDE1 other 0.00454350508277677 1 0.210042636595315 4.38281345836937 -0.707220634775471 0.00840860890214897 56.7628639968015 25.4043275497186 2.2343777407889 0.0269268551959202 -80.0868994469248 82.0457073151891 -0.976125407015637 0.330563527741254 CRLF1 other 1 1 1 2.2343777407889 -0.976125407015637 0.000433468884676855 79.9189070694706 20.1378274640065 3.96859627545793 0.000110278503197656 -41.7045977201672 83.4061312516463 -0.500018369085355 0.617771270236573 OSBPL7 other 1 1 1 3.96859627545793 -0.500018369085355 9.64587078432184e-06 646.476700251889 130.076314369299 4.96998014885693 1.79564089293941e-06 130.826346407582 502.116049676775 0.26055001924714 0.79479451151031 TMEM98 other 0.0798099348694789 1 0.0193139134444563 4.96998014885693 0.26055001924714 0.745021995373232 15.8211314475874 23.54440137297 0.671970002420648 0.502672062951231 65.7750970604548 124.991944014153 0.526234691197436 0.599529133973496 YBX2 other 1 1 1 0.671970002420648 0.526234691197436 0.000130534152816681 62.3256051528898 17.6334032602171 3.53451935699238 0.000536968129648841 -156.651175676143 71.08303157021 -2.20377736030316 0.0289958194438563 MAP3K14 other 0.942456583336439 1 1 3.53451935699238 -2.20377736030316 0.0366873218739051 415.737728454464 213.010667533098 1.95172257459766 0.052833877449293 -707.022273097667 696.935459154356 -1.01447309619681 0.311990617976737 TMEM132A other 1 1 1 1.95172257459766 -1.01447309619681 1.46288268445124e-12 1361.22564550207 178.960773594677 7.60627939944577 2.73614357931812e-12 -1102.18140517592 690.744155030859 -1.5956434768915 0.112645486714819 AP2B1 other 1.84879113660948e-08 1 3.68968961671049e-08 7.60627939944577 -1.5956434768915 5.81898538080443e-11 196.159441513941 30.7015723000371 6.38923113112692 1.93046234548445e-09 3.17148896440246 65.1291966973333 0.0486953490174448 0.961226008328175 ZNF263 other 6.95601512421362e-07 1 2.41500839420104e-05 6.38923113112692 0.0486953490174448 0.141243495788476 121.127351566358 138.402558205877 0.875181449942408 0.382865147337717 -145.876281058264 221.683596419483 -0.658038228422767 0.511515533545591 CX3CL1 other 1 1 1 0.875181449942408 -0.658038228422767 0.011431993342684 217.362331401333 74.2661255860697 2.92680316478101 0.0039335264605596 -166.712143166677 297.849793632943 -0.559718847319822 0.576468898013875 SPATA20 other 1 1 1 2.92680316478101 -0.559718847319822 0.792639910304142 14.4827474134663 36.5901741636544 0.395809742492351 0.692782742007278 85.9516751530257 146.74760178525 0.585710935697658 0.558910786118522 CACNA1G other 1 1 1 0.395809742492351 0.585710935697658 0.0467035637853322 315.369538385584 155.727892761325 2.02513199654561 0.0446394195414004 -71.0253641076278 333.712752357282 -0.212833832707676 0.831747483609993 TNFRSF12A other 1 1 1 2.02513199654561 -0.212833832707676 0.461687537951678 -12.866263975682 11.9158641841942 -1.07975919973547 0.281948602679673 -35.047074837032 37.5467874446712 -0.933424061610522 0.352071793451319 DLX6 other 1 1 1 -1.07975919973547 -0.933424061610522 0.0014240335255885 116.331783343027 33.9065612454058 3.43095197714246 0.000771098334836904 29.0606310140106 49.5493281842167 0.586498991590113 0.55839341880141 MAP3K9 other 1 1 1 3.43095197714246 0.586498991590113 1.75956823873033e-07 246.384289723305 61.4092006274966 4.01217223487166 9.36118532152021e-05 -215.364264580767 138.42475543042 -1.55582188974155 0.121803151870733 RALA other 0.00171645881688144 1 0.859169588809125 4.01217223487166 -1.55582188974155 3.85316754252698e-07 391.282102921321 79.5821988465267 4.91670384322887 2.27182151319134e-06 -355.906515898397 256.700121658661 -1.38646804527679 0.167647697156255 BAIAP2L1 other 0.00364316991145926 1 0.0242630537608836 4.91670384322887 -1.38646804527679 0.0026273981049135 77.2913173997601 22.6964185980205 3.40544113010417 0.000843818443619412 126.758750025411 81.7995370156818 1.54962674178841 0.123297155288876 KDM7A other 1 1 1 3.40544113010417 1.54962674178841 0.659800809279865 -23.2254091008751 34.7292973960332 -0.668755513134219 0.504665829705104 3.01629427358432 66.2022788621549 0.0455617891925562 0.963719328799943 ETV1 other 1 1 1 -0.668755513134219 0.0455617891925562 7.5460260641018e-11 149.260968229954 22.154655881327 6.7372280133567 2.98412480057666e-10 -99.5034039334343 77.6723525798934 -1.28106592150773 0.202083882240948 AGK other 8.9767526058555e-07 1 3.82743846921962e-06 6.7372280133567 -1.28106592150773 0.719195626988383 -88.5639388727175 111.122470092738 -0.796993972495448 0.426689584188582 -2.924788303784 345.770054673694 -0.0084587669297856 0.993261980230107 ALDH3B1 other 1 1 1 -0.796993972495448 -0.0084587669297856 3.82286982061188e-05 44.2230568074335 36.4751187077976 1.21241707701364 0.227209476746355 -406.54256940967 105.677915894735 -3.84699647005364 0.000174701292161771 TTC22 other 0.295123508421571 1 1 1.21241707701364 -3.84699647005364 0.00730271379559919 70.3149154646154 26.9895369658415 2.60526572032738 0.0100803773449031 -96.6968010080302 91.6388276601942 -1.05519465358714 0.292988923808732 PHTF2 other 1 1 1 2.60526572032738 -1.05519465358714 7.28458354014149e-06 152.679352226721 45.4329215211701 3.36054444915187 0.000999384648185404 -179.698866396761 97.2113966505713 -1.84853702948733 0.0666045736836127 FARP2 other 0.0609282567297434 1 1 3.36054444915187 -1.84853702948733 0.516433698188989 -20.9438800999166 47.457944821977 -0.441314519170198 0.659608341537651 -83.662795371673 74.0408633480816 -1.12995434667417 0.260263794259359 USH1C other 1 1 1 -0.441314519170198 -1.12995434667417 0.000493166154674242 4.24340698886016 61.6767469447521 0.0688007587796622 0.945240458787703 -439.892554060007 132.603082468864 -3.3173629592155 0.00114187776049713 GGCT other 1 1 1 0.0688007587796622 -3.3173629592155 2.22368449666895e-05 58.9560702570752 17.3948034935588 3.38929211122771 0.00089005907901357 -120.769042261042 53.9245051944451 -2.23959481548442 0.0265493975041342 DBF4 other 0.177227654384515 1 1 3.38929211122771 -2.23959481548442 0.883801098884616 -2.8844844403419 5.83012576525382 -0.494755097314152 0.621496890177272 -1.93502576770573 8.67012126218076 -0.223183241524701 0.823696539785986 TBXA2R other 1 1 1 -0.494755097314152 -0.223183241524701 6.55695027119631e-08 207.75103311435 38.8252522808566 5.35092551650424 3.16259283445447e-07 -101.63278882902 119.056741480257 -0.853650012300005 0.394642217469311 IFRD1 other 0.000662186407888116 1 0.00356613968013086 5.35092551650424 -0.853650012300005 9.29040101703316e-22 166.792605430388 14.3946482091425 11.5871262018375 9.33875385410592e-23 81.3300596957442 64.5429045816974 1.26009296022304 0.209529674589742 COX10 other 1.32434666497808e-17 1 1.34524749268396e-18 11.5871262018375 1.26009296022304 0.000598548401107145 195.119913419913 59.6014873001938 3.27374235540728 0.00132326418221804 -386.71341991342 244.753268862119 -1.58001329956199 0.11625318785446 GTF2IRD1 other 1 1 1 3.27374235540728 -1.58001329956199 3.07609980684219e-35 280.554773040224 22.1410866659459 12.6712287103655 1.16627017835224e-25 -296.212428372826 81.8714818676406 -3.61801718517449 0.000401990990204982 PAF1 essential 4.47387955907128e-31 1 1.68561028877249e-21 12.6712287103655 -3.61801718517449 4.19694631368702e-14 286.456544026573 44.4206773026656 6.44872076296285 1.36141600754979e-09 -170.330794245765 101.465080077181 -1.67871344620435 0.0952228046161084 VPS41 essential 5.53157524143949e-10 1 1.71061921348632e-05 6.44872076296285 -1.67871344620435 7.56153166404064e-05 139.533148420079 37.3423958901243 3.73658800122626 0.000262311810108594 -321.13117963779 168.922891406386 -1.90105187617958 0.0591632290560338 ARHGAP44 other 0.563863416187511 1 1 3.73658800122626 -1.90105187617958 1.82200027905923e-24 729.419855236434 58.2987950478967 12.5117483926925 2.58693565965887e-25 149.237796649448 261.666493164403 0.570335906766951 0.569270427234274 ELAC2 essential 2.62021860131507e-20 1 3.73760464107514e-21 12.5117483926925 0.570335906766951 0.605922320658331 -64.2856282064525 93.1864072964728 -0.689860571638175 0.491326912471598 -178.088162379919 177.914624004331 -1.0009754025368 0.318419159051642 SCIN other 1 1 1 -0.689860571638175 -1.0009754025368 1.13462689581483e-14 281.420132858332 35.0906048979922 8.01981424020519 3.56561358780097e-13 -125.22242813942 144.755045217298 -0.865064343363254 0.388462551910219 ADIPOR2 other 1.5115379626047e-10 1 4.87205440637125e-09 8.01981424020519 -0.865064343363254 1.21095062426587e-06 10.9496814458458 3.78887162957624 2.88995841410189 0.00439845954446439 -16.0150977332813 6.27150775701076 -2.55362798768421 0.0116132276369662 CDKL3 other 0.0109663688533517 1 1 2.88995841410189 -2.55362798768421 0.000120222393925282 361.484004616811 125.42994394571 2.88195938900581 0.00453656556467472 -360.154219512032 268.786606432125 -1.3399262124431 0.182309213341436 PRSS21 other 0.873295469473245 1 1 2.88195938900581 -1.3399262124431 1.10323681561265e-13 219.345901713859 29.8641617205612 7.34478683065936 1.05312350277176e-11 -232.223820692242 127.227647624142 -1.825262236855 0.0698619029659092 MARK4 other 1.43729692338016e-09 1 1.40339237979364e-07 7.34478683065936 -1.825262236855 0.000277864435147154 539.990529733153 155.013748491814 3.4835008829018 0.000648853929849586 76.6980600205871 292.857832161392 0.261895198275999 0.793761534980222 PROM1 other 1 1 1 3.4835008829018 0.261895198275999 1.95049664115801e-17 442.598675362994 47.6846515101184 9.28178483739316 1.67908920924451e-16 -134.953786784688 235.480394816233 -0.573099883283298 0.567429530425154 CCDC124 other 2.70397349363735e-13 1 2.36650833150922e-12 9.28178483739316 -0.573099883283298 0.998708484482077 -0.0455098934550992 1.57785534121827 -0.0288428807548103 0.977026532358174 0.0882357824823647 4.19886204605827 0.0210142132593275 0.983261001005806 CEACAM21 other 1 1 1 -0.0288428807548103 0.0210142132593275 1.91713329830928e-18 648.867585764669 65.2423717275772 9.94549352794911 3.25561748934946e-18 -305.202041252543 313.27678587269 -0.974224886795701 0.331513357411325 PAFAH1B1 essential 2.6834114776435e-14 1 4.63144144034855e-14 9.94549352794911 -0.974224886795701 0.144734814521891 -21.4952893674294 22.2026811569075 -0.968139352879101 0.334512717727023 -165.186702557201 88.3804303889282 -1.8690416173612 0.0635410932097604 DNAH9 other 1 1 1 -0.968139352879101 -1.8690416173612 1.98154247773253e-08 687.561480955213 111.31649325182 6.17663619172598 7.09919307583911e-09 -717.818404971631 713.581906314105 -1.00593694798038 0.316232322553443 KIAA0100 other 0.00020750712826815 1 8.69935119513325e-05 6.17663619172598 -1.00593694798038 0.467606908661565 -3.59474497188085 9.08623421844927 -0.395625391714188 0.693001319262095 -69.9596592972805 58.2462862906569 -1.20110076972414 0.231799746376597 SLC13A2 other 1 1 1 -0.395625391714188 -1.20110076972414 0.443231362914313 49.085456919443 52.5141759944142 0.934708695127657 0.351401769114513 -167.190910024504 228.332598358499 -0.732225320547536 0.465143960290776 GAS7 other 1 1 1 0.934708695127657 -0.732225320547536 1.09972257751654e-12 140.753543161798 19.9586353393447 7.05226288113639 5.28032093795048e-11 -65.1613282085176 64.0202188020771 -1.01782420347497 0.31032741386418 TRAPPC6A other 1.39444822829097e-08 1 6.93094926315379e-07 7.05226288113639 -1.01782420347497 0.778394238301974 2.64319419237749 16.5045445576846 0.160149477808329 0.872977363270413 -12.1078538130315 24.6652698515657 -0.490886736123138 0.624219207988409 MATK other 1 1 1 0.160149477808329 -0.490886736123138 0.579813209940267 -11.0182049974503 14.9163494084709 -0.738666324831 0.461212457235978 -40.0246200917898 39.474224299778 -1.01394316929022 0.312169909162813 CEACAM7 other 1 1 1 -0.738666324831 -1.01394316929022 0.944550102886985 0.964991352654502 5.50171579159539 0.175398255600309 0.860998625370269 6.63858026308887 22.6813376683852 0.292689097977769 0.770156362621772 CD79B og 1 1 1 0.175398255600309 0.292689097977769 5.75472127475125e-08 76.37830570494 18.9988179673996 4.02016092980093 9.15411059975059e-05 -191.805242926577 63.3330208274177 -3.02851877931491 0.00289123039969934 ST7L other 0.000583356095621534 1 0.841171223011082 4.02016092980093 -3.02851877931491 0.0294037882695189 102.770688988777 38.3482538605614 2.67993138259861 0.00817034717912207 74.2039552794318 62.2594625627093 1.19185023810143 0.235165382318724 PAX6 other 1 1 1 2.67993138259861 1.19185023810143 0.000254526027546762 161.257817215984 63.0153708865073 2.55902353580391 0.0116331753546125 -177.064235482313 134.783008785843 -1.31369849269095 0.19124372631924 RPUSD1 other 1 1 1 2.55902353580391 -1.31369849269095 0.00678760440864776 75.8934248866142 45.8581887978679 1.65495905695566 0.100363791119611 -138.267666658221 100.803568740763 -1.37165447995006 0.172552001575942 RHBDF1 other 1 1 1 1.65495905695566 -1.37165447995006 7.45251868263121e-06 118.662781564345 44.3028764677781 2.67844417846434 0.0083594992825301 -204.431119669598 97.3847456801615 -2.09921090045258 0.0377472421154593 LUC7L other 0.062280698630749 1 1 2.67844417846434 -2.09921090045258 0.326417910838678 68.8488399826542 63.2538469074245 1.08845300876986 0.278334480257124 -68.7530491110148 140.335591266922 -0.489918833065269 0.624986547958176 CACNA2D2 other 1 1 1 1.08845300876986 -0.489918833065269 0.00252144795210154 71.6161142647865 57.91113971678 1.23665523792196 0.218330892403323 -285.012415308552 128.82367294273 -2.21242267665553 0.0285933503056954 BAIAP3 other 1 1 1 1.23665523792196 -2.21242267665553 5.37241685454466e-08 307.638044314227 58.030829684369 5.30128633327281 4.48968458100107e-07 2.90941585790187 129.089923983801 0.0225379004659338 0.982051672612438 TSR3 other 0.000545407759073374 1 0.0050176714877268 5.30128633327281 0.0225379004659338 1.87830228418698e-10 416.518078870304 80.1281844776619 5.19814696396148 7.53128431464128e-07 -215.778010995514 172.015022687637 -1.25441375772944 0.211925236948846 PIGQ other 2.19705018181351e-06 1 0.00828516587453687 5.19814696396148 -1.25441375772944 5.79967464955445e-10 303.009763934101 53.0655723855306 5.71010073598532 6.64471514875956e-08 -73.1410476745406 117.06819903154 -0.624772980874465 0.533151709406662 CRAMP1 other 6.62496835218604e-06 1 0.000779358639798009 5.71010073598532 -0.624772980874465 1.01498014092507e-12 484.730962784391 72.9325826452689 6.64628819113724 5.06210076879845e-10 -272.074702425795 209.682786370224 -1.2975538294565 0.196406476511463 TEAD3 other 1.28861878691846e-08 1 6.45012879960299e-06 6.64628819113724 -1.2975538294565 4.01522293018709e-16 467.445669477402 72.4003208883483 6.45640328304995 1.40424681073205e-09 -364.720462403303 162.89085582819 -2.2390481070834 0.0266242524110976 DNAJC11 essential 5.48118082199839e-12 1 1.76373399427945e-05 6.45640328304995 -2.2390481070834 3.19516413708217e-11 314.769457207763 50.4956771353961 6.23359216203318 4.22872631653114e-09 -157.180146529748 140.210506389914 -1.12102973291205 0.26403165505796 MYLIP other 3.85560456421705e-07 1 5.22416849144257e-05 6.23359216203318 -1.12102973291205 7.49407493660969e-08 68.5943598842095 20.0485653764147 3.42140989124859 0.000801642023773948 -82.9519846457586 44.291671997379 -1.87285737713102 0.0630212658447338 E2F2 other 0.000753754057124203 1 1 3.42140989124859 -1.87285737713102 2.23352449026397e-09 576.725835406205 157.951558589219 3.65128296648266 0.000373032981619073 -882.919539353264 327.31570901731 -2.6974554383718 0.00788542309563212 PSMB1 essential 2.4740750778654e-05 1 1 3.65128296648266 -2.6974554383718 1.9353726360281e-16 248.938031906206 29.2910541267763 8.49877340804341 1.59663672436201e-14 -19.5767553061848 81.3313854585649 -0.240703575818936 0.810107105605331 JARID2 other 2.65262173494011e-12 1 2.21597210974204e-10 8.49877340804341 -0.240703575818936 5.67885139337098e-05 25.0942216857884 6.46658528320696 3.88059858283403 0.00015602554953682 -19.9049051107687 22.1003518515486 -0.900660100095824 0.369222501274836 CAMK1G other 0.42937795385278 1 1 3.88059858283403 -0.900660100095824 2.60893717621932e-12 236.560430107527 39.1230526250965 6.04657393108889 1.34540900046403e-08 -108.32688172043 89.3298738656314 -1.21266130839246 0.227361606315884 CDK11A other 3.27082453782616e-08 1 0.000162834851326162 6.04657393108889 -1.21266130839246 1.1947668730877e-08 277.767120669056 81.3014418583472 3.41650915801732 0.000836815911125342 -510.940597371565 185.636014037445 -2.75237862664139 0.00672424988591323 NADK other 0.000126812555909529 1 1 3.41650915801732 -2.75237862664139 0.00929301309457352 17.2395147445134 32.5963729559484 0.528878313173411 0.597651311257777 -177.739631955984 70.7111004591294 -2.51360296759511 0.0129785885457576 DLEC1 other 1 1 1 0.528878313173411 -2.51360296759511 2.96479578125278e-06 277.089201042578 61.264212226811 4.52285585615211 1.23180246097795e-05 131.945495465169 119.034405221353 1.10846519726634 0.269435097156276 CYTH3 other 0.0257966880926804 1 0.12405482584509 4.52285585615211 1.10846519726634 0.595105923940674 9.47921275459621 10.3384315662308 0.916890796623242 0.360633508946436 -5.04639942024553 32.0495029968038 -0.157456401765381 0.875091423362846 ADAM22 other 1 1 1 0.916890796623242 -0.157456401765381 3.13406579717903e-07 484.709546299472 105.741916764917 4.58389218891374 9.30012459332031e-06 -583.40769623525 331.846136675757 -1.75806686218948 0.0806973267383842 SYPL1 other 0.00298488426523331 1 0.0946845684845941 4.58389218891374 -1.75806686218948 4.68222583752734e-05 477.836977264053 110.413948748416 4.32768669792645 2.69089719277711e-05 -657.883512349381 443.171386328234 -1.48449004751882 0.13970975746724 CYB561 other 0.357581587211963 1 0.26209338657649 4.32768669792645 -1.48449004751882 4.38195253040701e-07 254.71127537511 44.8972525071586 5.67320406375642 6.57576291890564e-08 65.5115842894963 178.106003552109 0.367823560031369 0.71350020658873 SPAG9 other 0.00412604650263124 1 0.000771731536162766 5.67320406375642 0.367823560031369 0.000327054351740532 29.1917501958771 7.41572801477243 3.93646451673065 0.00012521066932234 2.28427849674436 22.9294667897775 0.0996219632007645 0.920774868385776 AASS other 1 1 1 3.93646451673065 0.0996219632007645 2.07277966101763e-12 121.541714614499 15.9542996317287 7.61811658424583 2.62428361141902e-12 8.97734246957491 69.310880397157 0.129522845736975 0.897116320311241 PLEKHG6 other 2.60589858983137e-08 1 3.54147073360997e-08 7.61811658424583 0.129522845736975 9.70309476557963e-06 24.7265503930573 19.6292601223736 1.25967816611049 0.209666814138445 -166.350588881688 43.1539954648672 -3.85481314278579 0.000168909152198674 SS18L2 essential 0.0802737029956403 1 1 1.25967816611049 -3.85481314278579 2.53216044427226e-08 130.631627162548 30.9328545910499 4.22307054714391 4.10796805998087e-05 -50.3957431723332 46.6074234154612 -1.08128146718394 0.281262255584756 MPND other 0.000263040826951002 1 0.391612595157976 4.22307054714391 -1.08128146718394 0.153383993191668 43.7541188258927 125.820970661178 0.34774901668592 0.72852952196267 -797.333665833911 483.356500540251 -1.64957679258006 0.101179416662954 MGST1 other 1 1 1 0.34774901668592 -1.64957679258006 6.23052402412361e-08 60.0874671370094 29.5282455016308 2.03491491337306 0.043552545720325 -219.977520050584 59.8421994786904 -3.67595980707422 0.000325436007793524 CRY1 other 0.000629905978838897 1 1 2.03491491337306 -3.67595980707422 2.17191959570765e-11 1046.35536765126 172.778533334356 6.05604959978671 1.08624685015977e-08 -2256.44551791121 1042.93086552628 -2.16356193156923 0.0320920106001198 NFIX other 2.63888230878479e-07 1 0.000132000717231415 6.05604959978671 -2.16356193156923 0.0305586775176117 171.851557643158 116.134181475191 1.47976724389166 0.140991484138954 -1336.92578745597 715.304743618715 -1.86902966796009 0.0635301755863884 ST3GAL1 other 1 1 1 1.47976724389166 -1.86902966796009 0.195426297847563 3.84919327199385 6.95678736367985 0.553300405887033 0.580881460125271 -17.8144525585933 14.9196584452973 -1.19402549488044 0.234352827222239 MMP25 other 1 1 1 0.553300405887033 -1.19402549488044 0.938535814906844 89.1072237997237 261.981863341961 0.340127452576415 0.734233230887966 149.433024200902 560.938871417648 0.266398054788471 0.790296090809423 IL32 other 1 1 1 0.340127452576415 0.266398054788471 0.0640634881366294 141.598750581511 66.0940465891483 2.14238283005598 0.0339177860625709 58.7361068651556 105.512895202656 0.556672307705542 0.578652966081864 MAPK8IP2 other 1 1 1 2.14238283005598 0.556672307705542 2.68698260678013e-13 228.55236645323 48.9932483361625 4.66497679200693 6.65406297425404e-06 -114.306840400603 89.7144114861274 -1.27411904628365 0.2045406379897 RHOBTB2 other 3.46835714883179e-09 1 0.0686166973905076 4.66497679200693 -1.27411904628365 2.73035106681403e-10 176.638406717471 24.8569747818157 7.10619084856183 4.32422611942109e-11 30.9628139994355 98.9013575663741 0.313067633865955 0.754658429563022 HEATR5B other 3.1713027641045e-06 1 5.69111399577009e-07 7.10619084856183 0.313067633865955 6.37123053815431e-10 689.960513139046 99.0993744790058 6.9623094673036 1.01477605334331e-10 509.778339360641 587.702988602312 0.867408111319982 0.387122650378568 SEC62 other 7.26320281349591e-06 1 1.32255763032233e-06 6.9623094673036 0.867408111319982 1.38010469624046e-17 3258.99115260236 371.873470959813 8.76370972145668 3.49148906866854e-15 -2564.12334492648 1256.47477356359 -2.04072807419297 0.0430082322614932 CSDE1 other 1.91627537072988e-13 1 4.87621363330249e-11 8.76370972145668 -2.04072807419297 0.00214393694072598 289.410635651619 89.7306942162679 3.22532482535 0.00154264798446165 -64.9186863423984 255.566911172512 -0.254018354897975 0.799826945116444 UBE3C other 1 1 1 3.22532482535 -0.254018354897975 1.17393714218287e-14 278.853011148216 36.8126978446349 7.57491375190954 3.10980415394217e-12 82.5324403043162 77.5123460797056 1.06476509199513 0.288648852012788 REV3L essential 1.56344948595914e-10 1 4.18859521494471e-08 7.57491375190954 1.06476509199513 3.95332633073749e-07 15.1270836146391 3.98133420832372 3.79950107755664 0.000207840208900798 -12.3889184355633 9.12096397518105 -1.35829046899808 0.176345235369613 MASP2 other 0.00373549804991385 1 1 3.79950107755664 -1.35829046899808 9.68868326242359e-12 80.3804462886907 15.6557433839583 5.13424653926383 8.49351692743127e-07 -55.869077359529 33.0105976044394 -1.69245882879792 0.0925939289252151 FAM76A other 1.19180492811073e-07 1 0.00931993612447033 5.13424653926383 -1.69245882879792 0.37243339369957 0.0631870235998451 5.67670049544473 0.0111309419354693 0.991133669293783 -25.4757358499362 19.2971018574026 -1.32018455611579 0.188771124469831 TRAF3IP3 other 1 1 1 0.0111309419354693 -1.32018455611579 7.06768160998271e-08 218.630633356658 37.8067361074146 5.78284866314552 3.92710694629798e-08 54.1967490591376 60.1366266743789 0.901226956952475 0.368865868104324 POMT2 other 0.000712492983102357 1 0.000465833425969867 5.78284866314552 0.901226956952475 3.0711276477774e-17 400.525245547219 53.3688155046379 7.50485544338927 4.60367638794804e-12 -111.721443502663 108.58620239557 -1.02887329179882 0.305152471610294 VTA1 other 4.24829087517047e-13 1 6.18181665373663e-08 7.50485544338927 -1.02887329179882 0.69452930996179 36.0249477351916 73.8639233833394 0.487720474151219 0.626479428951542 -177.084210748601 293.83333718631 -0.602668888575831 0.547663929998956 MLXIPL other 1 1 1 0.487720474151219 -0.602668888575831 0.00025099403637407 431.168641114983 103.51886756917 4.16512130821835 5.30177888323945e-05 123.679611445465 411.801769068468 0.300337737074903 0.764346774840286 BAZ1B other 1 1 0.500169819844809 4.16512130821835 0.300337737074903 2.85008657741807e-13 304.995515316917 45.5457525963391 6.69646449845757 3.88583703996324e-10 -197.30635368434 128.298043035192 -1.53787500585819 0.126158272666202 RANBP9 other 3.67490163292286e-09 1 4.96493398596103e-06 6.69646449845757 -1.53787500585819 0.0944257755411397 10.5904205486617 17.5600508899858 0.603097372269076 0.547331084683026 -82.9617643846954 51.1401624658768 -1.62224287887336 0.106796821165005 ETV7 other 1 1 1 0.603097372269076 -1.62224287887336 1.55439725894425e-13 78.7589594512928 11.0839651604417 7.10566645701675 3.94310282741824e-11 -65.9172716086239 35.1094811826921 -1.87747780337805 0.0623075562037211 SPRTN essential 2.01807396128732e-09 1 5.1966152162545e-07 7.10566645701675 -1.87747780337805 2.62782567348257e-09 78.6554408716408 16.2550849837195 4.83882064907193 3.12799113123331e-06 -199.410584681133 73.8573523632527 -2.69994223053613 0.00770577975264977 DYRK4 other 2.90138232609211e-05 1 0.0330910181773172 4.83882064907193 -2.69994223053613 0.0087221167625932 148.178354271654 241.87295140641 0.612628875655781 0.54139779209627 -1460.43262277111 552.205325694845 -2.64472752220098 0.00938287906579066 UQCRC1 essential 1 1 1 0.612628875655781 -2.64472752220098 7.36223445709662e-06 84.592618534483 47.467480335084 1.78211731352336 0.0766878796597424 -345.030118534482 110.32771030663 -3.12732057590566 0.00210736364777367 STARD3NL other 0.0615556422957848 1 1 1.78211731352336 -3.12732057590566 0.00429010317375734 1281.30067492736 627.731919445442 2.04115902861734 0.0429422915786568 -4928.71302774846 2699.70679428351 -1.82564752519968 0.0698405422188264 CD9 other 1 1 1 2.04115902861734 -1.82564752519968 8.51821833534908e-16 1334.10438229915 153.627848109457 8.68400097193726 6.01192837277317e-15 -316.46781988536 682.905425560146 -0.463413831608939 0.643739467613833 NCAPD2 essential 1.15737032522388e-11 1 8.38122934448308e-11 8.68400097193726 -0.463413831608939 0.742495016046148 -4.1301074792017 5.36161415713273 -0.770310462140825 0.442327270398818 -7.2439754001903 23.7331201697887 -0.305226424016999 0.760616838684174 IFFO1 other 1 1 1 -0.770310462140825 -0.305226424016999 0.649069021130291 -1.94364540887929 2.10482218036978 -0.923424993810086 0.357202777579414 -3.18486822365682 6.74139342120137 -0.472434706694399 0.637272578354556 GIPR other 1 1 1 -0.923424993810086 -0.472434706694399 5.61773326107362e-05 9.24227391973636 4.44556090095444 2.07898938416344 0.0394046028408754 -26.4620297899096 10.0647842367327 -2.62917010116651 0.00949541634175186 PHF7 other 0.42503769853283 1 1 2.07898938416344 -2.62917010116651 4.62355832717597e-08 60.9950610324567 10.2454672252084 5.95337037264459 1.93876936914247e-08 31.3607397610736 23.1958169787079 1.35199979331879 0.178509846668048 SEMA3G other 0.000471418007038862 1 0.000233137016639382 5.95337037264459 1.35199979331879 6.59873348353257e-10 669.413019601033 137.156102726512 4.8806652149911 2.78832459732583e-06 -652.108541535521 312.090614555206 -2.0894846276134 0.0384353695063765 NISCH other 7.51786524139426e-06 1 0.029600853925211 4.8806652149911 -2.0894846276134 0.848784826343301 -66.5365427847131 124.070981559714 -0.536278039782329 0.592629807310673 -125.85146123308 285.181517539781 -0.441303007006841 0.659684301252994 STAB1 other 1 1 1 -0.536278039782329 -0.441303007006841 7.39484881315596e-07 207.354547987484 55.8176577465151 3.71485577071585 0.000282163647924635 -109.202389729521 97.0592468324756 -1.12511062359678 0.262259252506992 FUZ other 0.00681509266620454 1 1 3.71485577071585 -1.12511062359678 0.122227259205813 24.8623626094509 12.0743084528584 2.05911276049644 0.0413915328925729 43.2978024666977 47.8448173573871 0.904963272056731 0.367085200430918 SLC6A13 other 1 1 1 2.05911276049644 0.904963272056731 0.429098541474088 -0.99712167664126 9.47225771863763 -0.105267583110553 0.916302271708711 -29.1462212152735 24.1958810422598 -1.20459433423265 0.230232213322278 PRSS3 other 1 1 1 -0.105267583110553 -1.20459433423265 6.95094443867929e-05 36.3280133696741 9.18498359755533 3.95515277559593 0.00011665699640526 3.04018455689347 19.5122313059542 0.155809169603568 0.876388825089138 ZNF200 other 0.520417210123918 1 1 3.95515277559593 0.155809169603568 0.919361367231979 -16.7337554782823 66.1971091223183 -0.252786801420011 0.80078852819825 -111.759896915701 290.225108733177 -0.385080041501334 0.700738524806096 CD4 other 1 1 1 -0.252786801420011 -0.385080041501334 0.0901987220270673 27.736543857425 24.4450928330275 1.13464669767792 0.258519261654671 -156.367213430253 107.613464061556 -1.45304507009281 0.148514727414534 LRRC23 other 1 1 1 1.13464669767792 -1.45304507009281 0.0422633042600866 4.44313819577731 7.14432211534412 0.621911795695021 0.534950320789822 -39.5385266188504 19.8435799876729 -1.99250975093266 0.0481418349363305 HFE other 1 1 1 0.621911795695021 -1.99250975093266 1.33100957427941e-20 296.299593652472 27.5914268983229 10.7388282144437 2.26279458119414e-20 -149.942381414917 185.275782597827 -0.809292932473497 0.419611692632092 SCMH1 other 1.88670607154107e-16 1 3.24281091430933e-16 10.7388282144437 -0.809292932473497 4.89127794497241e-10 758.397318684694 128.145650537844 5.91824471218182 2.05875620051491e-08 205.967552755583 270.903020478085 0.760299949377069 0.448245343252998 FYN other 5.61029580288335e-06 1 0.00024721544455783 5.91824471218182 0.760299949377069 5.76930497583772e-07 502.040951393714 114.039863732079 4.40232858023391 2.01587928476757e-05 -77.9397746819013 234.570285360451 -0.332266188627156 0.740149056124901 HIVEP2 other 0.0053717998630025 1 0.198846332649473 4.40232858023391 -0.332266188627156 9.13056030945761e-16 343.158448083364 53.6461564983712 6.39670146907511 1.88355480437514e-09 -186.209115317136 118.319045555373 -1.57378817960452 0.117629350496925 ELOA other 1.23974747881815e-11 1 2.35689212671461e-05 6.39670146907511 -1.57378817960452 1.43424978153677e-12 477.197059918124 95.0326422734131 5.02140157847245 1.42870499731786e-06 -422.79270561965 209.598828030427 -2.01715204990686 0.0454516094942188 LYPLA2 other 1.81317857381878e-08 1 0.0154585880709793 5.02140157847245 -2.01715204990686 2.48927227614247e-14 216.405701948914 31.9901694348225 6.76475635397382 2.61926049985469e-10 -70.0032384100266 73.3204594301868 -0.954757225391929 0.341196765860175 CLCN6 other 3.29579649361263e-10 1 3.36653552046323e-06 6.76475635397382 -0.954757225391929 0.298779431885508 304.176920977622 214.654381163852 1.41705433324203 0.158486912673434 606.852659348687 930.34195051443 0.652289901592774 0.515186605254489 MRC2 other 1 1 1 1.41705433324203 0.652289901592774 3.06980438236551e-07 3253.47639962195 686.709411615371 4.73777750033844 4.80325428695296e-06 -8117.02157113466 2713.81431529362 -2.99100108853852 0.0032296668453776 NME1-NME2 other 0.00292490961551786 1 0.0501507780100759 4.73777750033844 -2.99100108853852 0.00636843210418375 88.6811822812496 44.6360309696809 1.98676227152648 0.0487227657137876 -360.569947263911 211.716195725301 -1.70308155230479 0.0905701283825268 TSPAN9 other 1 1 1 1.98676227152648 -1.70308155230479 1.22744383420732e-09 250.087625519037 45.7302932645533 5.46875184185373 1.76491459796393e-07 -138.619253315194 80.1943341680194 -1.72854173244665 0.0858696969635364 BTBD7 other 1.37964686964902e-05 1 0.00202188616342748 5.46875184185373 -1.72854173244665 3.47649916910674e-09 125.930852994555 31.0244613089409 4.0590826619208 7.90471069936432e-05 -104.27328493648 46.5818513063651 -2.23849593805713 0.0266610293468156 APBA3 other 3.81198133892554e-05 1 0.731185739691199 4.0590826619208 -2.23849593805713 2.07454313794834e-10 136.877679937287 19.0672586830167 7.17867640088214 2.69200972411031e-11 34.5641091991198 72.1694077245994 0.478930204485223 0.632658905822864 MKS1 other 2.42265147649608e-06 1 3.55964445819106e-07 7.17867640088214 0.478930204485223 0.00322391609746322 10.3044709129835 16.9570413294743 0.607680945795213 0.544288393519414 -106.682435491992 37.3632086989646 -2.8552803468121 0.00488919326460589 ABHD5 other 1 1 1 0.607680945795213 -2.8552803468121 9.62607311704699e-21 448.521761479132 42.1812308893221 10.6332070454746 4.63223538915534e-20 -194.580199671685 256.069371994675 -0.759872991275704 0.448515246750573 AKAP8L other 1.36593977530897e-16 1 6.63428752434828e-16 10.6332070454746 -0.759872991275704 1.72092506666024e-12 236.74337021182 29.4330204639052 8.04346161149675 1.99652643242284e-13 55.2929685328292 116.31667037937 0.475365812591521 0.63518694910642 MBTD1 other 2.16888186151189e-08 1 2.73544086506254e-09 8.04346161149675 0.475365812591521 4.71226273647111e-13 193.92172124312 24.2527006667406 7.9958815270853 2.62777206007179e-13 -159.839363151164 95.8445088135714 -1.66769453075366 0.0973697590790538 UTP18 essential 6.0425345069769e-09 1 3.59558050979623e-09 7.9958815270853 -1.66769453075366 1.84006627345475e-16 360.625078941828 56.9710322044869 6.32997270696152 2.61788977231729e-09 -115.062395168647 111.394043893545 -1.03293130536321 0.303276720995088 RNF216 other 2.52273086090646e-12 1 3.25770203267164e-05 6.32997270696152 -1.03293130536321 2.37748417722731e-14 308.669658886894 37.9535160715964 8.1328343414774 1.26021164181724e-13 -303.531630917511 154.295921389052 -1.96720450019004 0.0509447732980105 TTC19 other 3.14969103799074e-10 1 1.73090069003597e-09 8.1328343414774 -1.96720450019004 0.0284460171571659 23.6946010651946 10.4060581963008 2.27700062965415 0.0241814536964859 -13.8019907135733 39.7791318495696 -0.346965609148221 0.729097058248536 DPF1 other 1 1 1 2.27700062965415 -0.346965609148221 0.598412649145829 -52.7855297157623 58.5188593170611 -0.90202595080955 0.368498901459728 -138.45142118863 191.149131418692 -0.724311013924343 0.47001059113358 SYT7 other 1 1 1 -0.90202595080955 -0.724311013924343 6.99882052873223e-09 136.882578178274 26.7091514176866 5.12493175232934 8.74780147220153e-07 -98.82481604587 58.935869984328 -1.67681950011341 0.0955934301681315 LARS2 essential 7.53423029918025e-05 1 0.00958759041353288 5.12493175232934 -1.67681950011341 4.34809886018683e-10 275.220239977566 74.0471162626262 3.71682590583852 0.000281276343131602 -312.416318116456 113.790729291059 -2.74553401725147 0.00675574746682269 PIK3C2A other 4.99900925955679e-06 1 1 3.71682590583852 -2.74553401725147 0.0481289706063704 48.0424189635803 41.653247503338 1.15338951566094 0.250526013823094 -163.793923804083 118.822396694754 -1.37847685588145 0.170042472023705 PLAUR other 1 1 1 1.15338951566094 -1.37847685588145 0.0145292695366416 128.086973632428 63.5077178173738 2.01687256343807 0.0454464908120692 -130.374655647383 155.007977732808 -0.841083520695395 0.401605228589457 ANLN essential 1 1 1 2.01687256343807 -0.841083520695395 1.85363119024966e-30 734.914869323322 51.3533709877652 14.3109372410706 5.81212864946644e-30 -51.3053752450919 312.326197260096 -0.164268561827897 0.869737966372856 WIZ other 2.6870237733859e-26 1 8.43281745751086e-26 14.3109372410706 -0.164268561827897 0.00245751184376696 -628.133786212469 785.560504197026 -0.799599499792223 0.425198930184484 3836.89766937625 1639.16383126224 2.34076520979702 0.0205521498026772 DCN other 1 1 1 -0.799599499792223 2.34076520979702 1.89873210597406e-11 60.9214302306449 12.3992357122392 4.91332140500481 2.23119671882024e-06 -135.760530009001 39.7126782670684 -3.41856897930705 0.000802052807274321 QPCTL other 2.31132659260223e-07 1 0.0238514929241883 4.91332140500481 -3.41856897930705 1.01548606850179e-14 407.626316100967 73.1087019095316 5.57561966570524 1.05243609822691e-07 -362.674941555944 150.139378794946 -2.41558839837263 0.0168581002733275 PPP5C other 1.35445531816769e-10 1 0.00122114160477268 5.57561966570524 -2.41558839837263 9.4083232639673e-15 258.797887323944 29.0628664166521 8.90476127212492 1.57875519393898e-15 97.936555697823 121.024246187951 0.809230867224139 0.419655640091741 MAP4K3 other 1.25554073957644e-10 1 2.21057302255336e-11 8.90476127212492 0.809230867224139 0.254490881827937 -120.631125361041 87.2661113818647 -1.38233643565457 0.168869949484337 121.92733022551 383.273271186608 0.318121140689056 0.750824029644599 TYROBP other 1 1 1 -1.38233643565457 0.318121140689056 0.0555323382119561 27.6830232558138 24.759215816096 1.1180896625093 0.265236620674622 -98.0281395348837 67.0482733862115 -1.46205315340817 0.145725415566423 TMEM159 other 1 1 1 1.1180896625093 -1.46205315340817 1.17419905683457e-07 134.629305581138 22.6693806145405 5.93881711504659 1.82067051773149e-08 92.2834776201877 89.3270341563085 1.03309685015071 0.303167797116643 BRCA1 ts 0.00116116544730371 1 0.000219099490103808 5.93881711504659 1.03309685015071 2.32588138146404e-18 323.680386882086 44.2775155470938 7.31026533179844 1.27584089661469e-11 -548.262435079072 141.909075759924 -3.8634768928141 0.00016316078653643 ERCC1 ts 3.25414064080634e-14 1 1.69801664930449e-07 7.31026533179844 -3.8634768928141 0.677678458088809 176.211517293321 389.770282823858 0.452090693053049 0.651835680749426 -422.27840942008 851.603810818053 -0.495862517353507 0.620693772347591 LTF other 1 1 1 0.452090693053049 -0.495862517353507 2.72446250924083e-11 648.096283560375 107.649766888207 6.0204151137031 1.25308040237215e-08 258.662945818455 197.124401198164 1.31218126343693 0.191437108730701 EXTL3 other 3.29796186743602e-07 1 0.000151823221551409 6.0204151137031 1.31218126343693 9.54589522621461e-05 208.117200834439 80.5782556946054 2.58279605385368 0.010749995265026 -521.839268781664 240.651262468479 -2.16844600534774 0.0316904912827532 ELOVL5 other 0.702005134935823 1 1 2.58279605385368 -2.16844600534774 0.123761902894491 -125.771547685777 81.8187614992751 -1.53719691402187 0.126351832429663 -344.410305085858 183.38012879459 -1.87812227720509 0.0623054095842385 ALOX5 other 1 1 1 -1.53719691402187 -1.87812227720509 0.022132892894062 165.060335689046 78.3766363960297 2.10598902018469 0.0369775362744885 -226.889732458355 209.775729539012 -1.08158237827108 0.281284486897669 CALCOCO1 other 1 1 1 2.10598902018469 -1.08158237827108 8.82457782110002e-05 181.498458578037 54.6153329797769 3.3232143553028 0.00110882474303394 -141.051915455506 95.7754685354883 -1.47273532160525 0.14283715992356 UBR7 other 0.651959809422869 1 1 3.3232143553028 -1.47273532160525 1.20881668158025e-05 192.804119818438 42.5181178145054 4.53463440361091 1.14374065855818e-05 12.8275548499956 69.5197025759353 0.184516825801783 0.853847679567237 MAP4K5 other 0.0990262625550541 1 0.115472056888034 4.53463440361091 0.184516825801783 1.16887889897905e-17 149.636912201515 15.015946107067 9.96520040326269 2.58524148992736e-18 -29.8150190008249 97.6796825660412 -0.305232554176934 0.760606616668268 EHD3 other 1.6238065664617e-13 1 3.67905716431563e-14 9.96520040326269 -0.305232554176934 4.92314591843904e-17 616.788523296689 77.6761478370867 7.94051379311838 3.61474847385686e-13 -362.633170066758 278.693473361114 -1.30119003395849 0.195099728515423 PSMC4 essential 6.79443368203772e-13 1 4.93810789013586e-09 7.94051379311838 -1.30119003395849 0.000170198274091135 153.504790552585 80.9991750971886 1.89514017109926 0.0599477553545694 -314.206795043191 154.329708496317 -2.03594497847891 0.0434697558689543 MAN2B2 other 1 1 1 1.89514017109926 -2.03594497847891 0.000443916293302885 1253.43661932841 322.554449403095 3.88596908722841 0.000150327602641566 -836.355673670524 1264.96048297283 -0.661171384346311 0.509477707694537 SLC25A39 other 1 1 1 3.88596908722841 -0.661171384346311 0.0102571519178419 -223.140944389895 203.843156775937 -1.09466978396125 0.275392924887421 -1331.17558372901 435.48054338916 -3.05679691994742 0.00264363531132333 MVP other 1 1 1 -1.09466978396125 -3.05679691994742 0.0011455368514593 337.48087431694 93.0789514397882 3.62574856180296 0.000393330782708923 20.1720069547941 295.66124231644 0.0682267543650663 0.945695390693956 NUB1 other 1 1 1 3.62574856180296 0.0682267543650663 6.56574329622499e-11 201.977186765377 39.697757780049 5.08787392689681 1.04742095726968e-06 -128.384895266833 76.2222878107133 -1.68434848853734 0.0941532518779216 PGM3 other 7.83293175239642e-07 1 0.0114357420114703 5.08787392689681 -1.68434848853734 3.96854309159578e-06 42.8419231208725 14.0471164993619 3.04987312683129 0.00270169498968875 -49.1787975688015 26.6802274289896 -1.84326755458486 0.0672375343047961 RWDD2A other 0.0341413762169985 1 1 3.04987312683129 -1.84326755458486 0.00423411228688414 77.6867476720419 62.4880624702614 1.24322541939933 0.215698973790375 -478.168937845408 188.248083702771 -2.54009989605206 0.012085763645846 CLK1 other 1 1 1 1.24322541939933 -2.54009989605206 6.94342114035548e-18 104.437741492781 17.6703424412408 5.91034055169374 2.0968686058e-08 -127.728566392761 35.7742159532112 -3.57040854675379 0.000474961850433468 POLR3B essential 9.66593656948887e-14 1 0.000251750044812348 5.91034055169374 -3.57040854675379 3.11644861201404e-12 304.652804377565 44.8988110760879 6.78532008033095 2.3866185603994e-10 -51.2598459212324 71.573852098749 -0.716181180950135 0.474971169909845 ANGEL1 other 3.89743063418476e-08 1 3.07277139651422e-06 6.78532008033095 -0.716181180950135 0.0018782223757134 116.831618498118 53.7457618101289 2.17378290982007 0.031279423348987 -116.596756838499 80.747241684659 -1.44397200951882 0.15081847209336 RNF14 other 1 1 1 2.17378290982007 -1.44397200951882 6.10458854918512e-23 313.705951338915 26.5900071499835 11.7978889426177 4.62537231587948e-23 -341.333605936502 253.885883670994 -1.34443711876013 0.180864074982185 DDX11 essential 8.74116034357818e-19 1 6.66793673057186e-19 11.7978889426177 -1.34443711876013 5.60250456870066e-07 106.173762736536 27.5542851371332 3.853257749498 0.000171077892164027 -261.534648575588 108.669348842872 -2.40670116606428 0.0172892569775127 HEBP1 other 0.0052237752598565 1 1 3.853257749498 -2.40670116606428 0.266151037264281 8.32169456234483 19.2218621154167 0.432928636797914 0.665692636395172 -84.4419316088732 62.1542227177189 -1.35858720319578 0.176330680817706 CD6 other 1 1 1 0.432928636797914 -1.35858720319578 0.000164310170387744 656.464481623696 159.53707049986 4.11480842394101 6.49349747280761e-05 377.428071859573 285.213663588608 1.32331693759235 0.187827269197616 TACC3 essential 1 1 0.606557598934959 4.11480842394101 1.32331693759235 2.21348351776965e-09 218.259864518548 47.0399069890333 4.63988724657624 7.5405195161976e-06 -104.792972220653 95.6241388926031 -1.09588408778611 0.274885877636004 UFL1 essential 2.452318389337e-05 1 0.0773280276386063 4.63988724657624 -1.09588408778611 0.176911143992088 41.4651325840047 49.2240617550191 0.842375275538425 0.400994475095083 -210.519959556897 154.41964216528 -1.36329780722825 0.174946306627128 POLA2 essential 1 1 1 0.842375275538425 -1.36329780722825 1.60688221486303e-09 463.462969168901 71.1755788818163 6.51154478052731 2.08194030867641e-09 -137.18359025916 296.408962593486 -0.462818630917387 0.644376619046312 ZC3H3 other 1.79408399289457e-05 1 2.6011762216603e-05 6.51154478052731 -0.462818630917387 0.000823099622787312 -231.401214064828 395.491394400175 -0.585097975180434 0.559403953001002 -4803.75409460543 1254.81552162682 -3.82825523896736 0.000192398242799514 CAPN1 other 1 1 1 -0.585097975180434 -3.82825523896736 0.506717082701698 177.106096992724 172.634121348176 1.02590435546359 0.306577310351826 -267.216751240444 692.262870535679 -0.386004742726805 0.700036471964199 ACPP other 1 1 1 1.02590435546359 -0.386004742726805 1.79727282596125e-14 374.32992403322 70.7639017774986 5.28984290903316 4.13712551389838e-07 -283.375165428342 122.523659822654 -2.312819955252 0.0220563227106438 SLC30A9 other 2.38605940374615e-10 1 0.00463233943791201 5.28984290903316 -2.312819955252 2.88548000279379e-17 240.839085992042 37.8607839685179 6.36117535739105 2.08788100840469e-09 -155.194281493483 64.8541648891154 -2.39297324634165 0.0178936257325123 COX15 essential 3.99292722786605e-13 1 2.60838974379998e-05 6.36117535739105 -2.39297324634165 2.21654473876887e-06 427.872064154507 87.2778256393751 4.90241434201671 2.36636415285429e-06 -2.01295617936443 153.612851243132 -0.0131040870804384 0.989561601984155 CCDC88C other 0.0195853893117617 1 0.0252420064184967 4.90241434201671 -0.0131040870804384 2.61144869345647e-06 42.305875869086 13.7714228892843 3.07200470199812 0.00254006638314686 -131.262524906733 42.525714324829 -3.0866624345001 0.00242551354131563 YAF2 other 0.0228762905546787 1 1 3.07200470199812 -3.0866624345001 1.31826878202484e-11 411.920673633949 55.5807830418974 7.41120673531063 1.0274770059417e-11 175.418893583157 199.340544710643 0.879996058191722 0.380348298094859 ZMYND11 other 1.6135609891984e-07 1 1.36942135351909e-07 7.41120673531063 0.879996058191722 0.598533113608553 12.1989885128705 12.2074115919968 0.999310002856641 0.319406308625483 9.8768951550431 21.5360720809295 0.458621011200517 0.647233068603672 DPEP1 other 1 1 1 0.999310002856641 0.458621011200517 1.43117661991491e-05 70.1804580127015 75.7210552601994 0.926828842671846 0.355610425557626 -401.501268523808 113.405034618626 -3.54041837625669 0.000542866879177719 BID other 0.116268788601888 1 1 0.926828842671846 -3.54041837625669 4.48439131678995e-07 1255.49616754523 275.114118965467 4.56354683745921 1.03956654721486e-05 -258.369872251509 403.965271354968 -0.639584366707792 0.523418452755094 MATR3 other 0.00421936378996767 1 0.105391256556643 4.56354683745921 -0.639584366707792 0.389094339344804 1.70029376153709 5.14902590094957 0.330216587417734 0.74170645318676 -12.0382386217026 11.970458006213 -1.00566232431996 0.316230556838167 NPC1L1 other 1 1 1 0.330216587417734 -1.00566232431996 3.95629868280468e-12 374.935780415082 48.4665842013459 7.73596461548595 1.13714118769463e-12 -191.478218319189 197.271462054054 -0.970633138343762 0.333214543667318 XYLT2 other 4.93033941851119e-08 1 1.54253202110777e-08 7.73596461548595 -0.970633138343762 1.37315277957461e-08 330.562335007246 89.3787930335869 3.69844259233872 0.000305737379272807 -572.286377801155 207.787863031966 -2.75418578087553 0.00662731092998997 NUDCD3 essential 0.000145213215199728 1 1 3.69844259233872 -2.75418578087553 8.04626253663507e-05 71.9133828184697 29.557342341318 2.43301248089353 0.016199638151505 -135.763726667394 64.6966482124536 -2.09846615579787 0.0376099874536993 CHDH other 0.59775684384662 1 1 2.43301248089353 -2.09846615579787 0.604479535584694 17.9236317954328 42.4811219374403 0.421919925321841 0.673671867361882 -44.022470771787 87.0560608779483 -0.505679562431685 0.613804648335037 IL20RA other 1 1 1 0.421919925321841 -0.505679562431685 6.53744968274126e-16 273.483256356024 42.4358561025837 6.44462681970903 1.68520646176448e-09 -294.317684637631 95.6803514354751 -3.07605145907216 0.00251705027838439 GLT8D1 other 8.90335272292532e-12 1 2.11139517594472e-05 6.44462681970903 -3.07605145907216 1.17303288851362e-12 594.52613475767 75.0843771732737 7.91810703025038 4.70362517683047e-13 -170.537575858342 297.663034166814 -0.572921580053407 0.567544347263944 ATP2C1 other 1.48646727632446e-08 1 6.41997800385591e-09 7.91810703025038 -0.572921580053407 0.728057206619466 82.6748249223885 117.236340688012 0.705197931266054 0.481738680884125 16.7455484014942 240.182981216798 0.0697199623248038 0.94450584448232 IGF1 other 1 1 1 0.705197931266054 0.0697199623248038 1.20540169695422e-21 988.341238347264 102.842913874169 9.6102026004098 2.33927493452032e-17 -191.107029293247 274.995869946013 -0.694945088923572 0.488157697432945 RALBP1 other 1.71781795832946e-17 1 3.31288116226767e-13 9.6102026004098 -0.694945088923572 3.37111448553569e-13 152.415561554949 20.8521834123428 7.30933344201891 1.36430944574503e-11 -13.0398871093855 52.2203746196254 -0.249708800527925 0.803145326735989 RUFY3 other 4.33896145433299e-09 1 1.81480442473004e-07 7.30933344201891 -0.249708800527925 0.278061620747176 17.0325082374329 23.1161527088477 0.736822794517777 0.462428881431206 108.138125923161 67.8980357947124 1.5926547013836 0.113430427910712 CNTN1 other 1 1 1 0.736822794517777 1.5926547013836 0.10797733711442 -41.1844704897446 23.0288465728423 -1.78838615991793 0.0758018222329035 20.1269540951584 59.5124122508228 0.338197584905998 0.735703471855404 SLC11A1 other 1 1 1 -1.78838615991793 0.338197584905998 8.08740468975486e-08 476.114901888131 80.6767005267433 5.90151677968418 2.28382477258945e-08 -276.812516681687 327.259711684692 -0.845849662510216 0.398975004436525 WWTR1 other 0.000810843194194823 1 0.000273739237242572 5.90151677968418 -0.845849662510216 0.00715590169969909 95.7166850557802 35.318772861806 2.71007957808435 0.00754403343626501 -122.762535245801 129.948672693554 -0.94470018585954 0.346394365606108 AGPS other 1 1 1 2.71007957808435 -0.94470018585954 4.84771343383436e-16 120.447408759124 12.885545519672 9.34748230684062 1.03433872404138e-16 -3.68584222346997 52.2606436250375 -0.0705280679265138 0.943865462622922 TTC27 essential 6.61179635240668e-12 1 1.4599691089844e-12 9.34748230684062 -0.0705280679265138 0.000328836580587752 13.3700810733927 3.86128395503378 3.4625998059435 0.000690573076778831 0.550445666603444 7.75991731983836 0.0709344757058455 0.943540759630239 ZNF582 other 1 1 1 3.4625998059435 0.0709344757058455 0.000358726919097918 95.539117020624 38.4192574689166 2.48675074207045 0.014049892401245 -237.147336775031 101.531275976425 -2.33570724384567 0.0209063572137784 VSIG2 other 1 1 1 2.48675074207045 -2.33570724384567 0.779702761228636 -11.8794194181258 17.0042043767227 -0.698616598280113 0.485838542920972 -8.82105578496619 47.3156695297398 -0.186429905201316 0.852351419604376 MARCO other 1 1 1 -0.698616598280113 -0.186429905201316 0.0992804402124316 -35.4552165236001 17.2805687568883 -2.05173898049317 0.0418887740328433 -96.4599074493035 76.4797690891011 -1.26124736774408 0.209126974346645 CYP24A1 other 1 1 1 -2.05173898049317 -1.26124736774408 9.83170349999204e-05 193.851323529411 43.9954955213772 4.40616297718979 2.02470325806708e-05 140.84830882353 77.78707658974 1.8106903485573 0.0722448669704576 PRDM11 other 0.721843670969415 1 0.199676235310576 4.40616297718979 1.8106903485573 0.265856582834082 82.783970588235 53.6138645055246 1.54407766259238 0.12473429214483 118.527426470588 94.7930176746567 1.25038140337922 0.213160568615946 SYT13 other 1 1 1 1.54407766259238 1.25038140337922 0.29275412982474 -3916.79434131493 10355.6795619333 -0.378226684003701 0.705783058583619 -25634.6018420121 16641.4758265913 -1.54040435530668 0.125514090983352 CD74 other 1 1 1 -0.378226684003701 -1.54040435530668 0.584690869216918 -21.2713625215686 23.3749541297077 -0.910006599522451 0.36426932158703 -55.6501559083904 71.7969939259434 -0.775104260852369 0.439490174051887 HGF other 1 1 1 -0.910006599522451 -0.775104260852369 8.45375726160463e-11 372.301170208824 57.4206559112164 6.48374986841799 1.15047202254937e-09 -26.0289054003101 106.467189763674 -0.244478185796833 0.807185927068266 ZRANB1 other 1.00396821238817e-06 1 1.44832922918741e-05 6.48374986841799 -0.244478185796833 1.25699031582544e-10 309.797332153317 53.7304657404279 5.76576673743997 4.52611420442857e-08 -362.570902887353 182.565797120194 -1.98597387137444 0.0488709034282047 NCDN other 1.48211728138977e-06 1 0.000535077221247545 5.76576673743997 -1.98597387137444 0.0375807381579641 121.772123593983 49.3350951810696 2.46826570714124 0.0148269076742306 258.221066540182 168.304006983684 1.53425382537217 0.127307487784291 ADGRA2 other 1 1 1 2.46826570714124 1.53425382537217 2.04353991535954e-10 126.85015173628 19.7468328629337 6.42382262597598 1.5493983558566e-09 -124.468647346352 89.821363695418 -1.38573544450319 0.167818293597978 ZFP64 other 2.38705897513148e-06 1 1.94356529758651e-05 6.42382262597598 -1.38573544450319 9.90865600307016e-07 38.1953976920635 25.1258010933296 1.52016636405689 0.130467807910799 -134.245219031999 34.9757122520954 -3.83824117903292 0.000178865938992099 MNAT1 essential 0.00904263946840183 1 1 1.52016636405689 -3.83824117903292 0.0407144198600214 50.2073161365032 29.2768978217081 1.71491243513087 0.0883343412220362 -37.0991249940917 43.1081613687003 -0.860605598016259 0.390767642505365 SAMD4A other 1 1 1 1.71491243513087 -0.860605598016259 0.000641049750296871 -438.286026508741 134.329696714619 -3.26276346353906 0.00135900289494288 -1099.7263465877 295.757127708215 -3.71834266551527 0.000280303988452727 RUNX3 other 1 1 1 -3.26276346353906 -3.71834266551527 4.50852681806606e-15 203.970139008066 27.5927853563255 7.39215473806115 8.4400479761244e-12 -124.332918597334 77.2346069134853 -1.60980839504506 0.10947442323154 MRE11 other 6.05314810593549e-11 1 1.1263244024138e-07 7.39215473806115 -1.60980839504506 0.00123681409301861 360.717187115233 98.1106122865394 3.67663781428386 0.000326560920161574 152.202992530399 376.138598317959 0.404646035293987 0.686302853859388 PLEKHB1 other 1 1 1 3.67663781428386 0.404646035293987 0.00489617200708823 -260.289085657595 106.765360772984 -2.43795444302435 0.0159973558923733 -850.167624384486 272.775073527139 -3.11673502051096 0.00221084217397693 SERPINB1 other 1 1 1 -2.43795444302435 -3.11673502051096 1.43686468722415e-14 8.44500108726562 0.989738042666983 8.53256187314921 1.4550650147728e-14 1.87235780517314 4.80535170627895 0.389640117855808 0.697355341495386 SLC7A9 other 1.91074266107067e-10 1 2.02021226651055e-10 8.53256187314921 0.389640117855808 4.68233231657102e-16 170.268650472908 18.1139205915908 9.39987837596871 7.207320614779e-17 1.59556727783202 112.309678694303 0.0142068546218088 0.988683339809853 SPAST other 6.3885742127295e-12 1 1.01832232966213e-12 9.39987837596871 0.0142068546218088 0.00150089102160993 61.0972828411044 21.3647623591245 2.85972208883526 0.00482080830819027 -29.8863178186705 34.0641667324202 -0.877353556111695 0.381643781200886 NRXN3 other 1 1 1 2.85972208883526 -0.877353556111695 0.0196167529107835 -46.9930699930699 33.8822203407684 -1.38695367424094 0.167473163031012 -148.992803454342 53.5883417366622 -2.78032121588134 0.00611281818474783 OSBPL5 other 1 1 1 -1.38695367424094 -2.78032121588134 8.36641080136927e-17 502.664539394083 66.2380105971402 7.58876262832365 3.09217737173611e-12 -103.954117340039 97.4321382458908 -1.06693868380153 0.28770240097035 AQR essential 1.1523894237806e-12 1 4.16547213746571e-08 7.58876262832365 -1.06693868380153 0.889470668948815 13.1703541684193 108.169616247073 0.121756502660937 0.90325163193807 -122.078993858837 312.620614828486 -0.390502059263794 0.696708498368045 CPS1 other 1 1 1 0.121756502660937 -0.390502059263794 7.39341174686879e-12 397.33193307354 53.0628368879754 7.48795119854551 5.05954343457182e-12 16.8909120160166 218.263952909558 0.0773875474665102 0.938415700518235 RTFDC1 essential 9.13012416620827e-08 1 6.78889538050847e-08 7.48795119854551 0.0773875474665102 0.0381728635566108 384.414400591025 193.525662175524 1.9863742940839 0.0487322568518488 -95.0249424601504 403.500146034565 -0.235501630901542 0.814126322692133 NLRP2 other 1 1 1 1.9863742940839 -0.235501630901542 4.6624266286878e-08 370.23516695267 60.8412896171866 6.08526165836046 1.01230773782813e-08 131.550397369405 282.910852138406 0.464988869727229 0.642646701562213 SLC45A4 other 0.000475241146262147 1 0.000123147236306792 6.08526165836046 0.464988869727229 4.70408526775768e-11 523.649111333386 138.348684810973 3.7849952245578 0.000218777573592574 -976.344425636684 277.493383364926 -3.51844218336808 0.000568954759055212 RNF10 other 5.64113905309501e-07 1 1 3.7849952245578 -3.51844218336808 4.36902227175873e-06 75.6661125011233 16.1869041527055 4.67452650533404 6.67491437375612e-06 0.454195025280359 27.8228714110238 0.0163245201607912 0.986997936385567 ZNF839 other 0.0373900926017112 1 0.0688050173646781 4.67452650533404 0.0163245201607912 3.93287910299068e-06 137.200293624161 37.0496218904184 3.70314963078321 0.000296775802231044 -114.405285234899 70.497100708927 -1.62283674199969 0.106683003801844 ZDHHC6 other 0.0338463575603378 1 1 3.70314963078321 -1.62283674199969 0.0639761386036973 56.6148365477352 34.4150919527388 1.64505841290451 0.101984248138597 -98.5713892646024 92.2147001739186 -1.06893357651974 0.286761472440721 GRAMD1B other 1 1 1 1.64505841290451 -1.06893357651974 0.00294992628330375 321.27985947346 141.358529917056 2.27280136304457 0.0244681788448353 -242.941363513358 244.210630122717 -0.994802574283023 0.321445092154425 RNH1 other 1 1 1 2.27280136304457 -0.994802574283023 9.94832779108639e-09 399.921569827955 78.7002215307759 5.08158124652248 1.07087599290095e-06 -349.41743096798 225.413284349065 -1.55011907118521 0.123165574198506 NDUFS1 other 0.000106079019236354 1 0.0116843279585423 5.08158124652248 -1.55011907118521 3.27447538644633e-08 274.200795695789 138.250784890784 1.98335796727955 0.0490939835281671 -825.987281291697 207.089159346099 -3.98855876328736 0.000102195064328852 ERP44 other 0.000337598412342616 1 1 1.98335796727955 -3.98855876328736 0.000127582829279203 83.4523287003166 46.42801256178 1.79745640822488 0.0744032747150279 -294.414736243193 106.637604967295 -2.76089036633454 0.00653163285710905 ALAS1 other 0.922934187005758 1 1 1.79745640822488 -2.76089036633454 0.26256509950641 -67.2307282540657 103.661237558227 -0.648561890999055 0.517587523124169 -471.91755180004 288.490376242012 -1.63581731199294 0.103920027043537 BIRC3 og 1 1 1 -0.648561890999055 -1.63581731199294 5.7206472781454e-10 208.054126591153 39.2913934530329 5.29515775101872 4.06562063934666e-07 -58.6115066932498 67.2971639268014 -0.870935761230609 0.385153719628088 AKAP11 other 6.53698364473675e-06 1 0.00455593448845187 5.29515775101872 -0.870935761230609 0.387288211839558 -8.99663022010466 9.50022514973965 -0.94699126371244 0.345229658207606 -43.1263616557735 37.734724878208 -1.14288263118301 0.25498390809011 GLRX2 other 1 1 1 -0.94699126371244 -1.14288263118301 5.7284268415067e-06 75.9155801555402 23.6025558705915 3.21641353469393 0.00158024257537125 -59.3674180419235 33.613053193129 -1.76620129390861 0.0793306787228206 SNAPC1 essential 0.0484166636644147 1 1 3.21641353469393 -1.76620129390861 5.44582438630186e-05 114.980559850297 34.1463700299674 3.36728500714389 0.000969085737315267 -215.130121294 131.58290208024 -1.63493978239523 0.104201287354018 DERA other 0.412684571993955 1 1 3.36728500714389 -1.63493978239523 8.40779363754942e-17 576.429618768329 74.8190980661476 7.70431124762701 1.79711953961747e-12 -808.925912670006 279.930316216005 -2.88974028824305 0.00443978664616371 STRAP essential 1.15800541769968e-12 1 2.43114331319451e-08 7.70431124762701 -2.88974028824305 0.000123785369256298 40.8603063535484 13.2972923363534 3.07282906324023 0.00251090279470218 -55.1746718510281 39.3404271511023 -1.40249295309144 0.162793889921278 DEF6 other 0.89769149784667 1 1 3.07282906324023 -1.40249295309144 0.00525965947023057 69.0977338791012 37.3494777096503 1.85003213207578 0.0662252466140345 -253.286152142532 116.079316796645 -2.18200932889926 0.030624541583818 GCLM other 1 1 1 1.85003213207578 -2.18200932889926 1.7225919825942e-17 247.553214482034 32.1255776008697 7.70579808891381 1.64697179018315e-12 -231.658262955375 93.2364660120089 -2.48463152738476 0.0140673237882287 UBR2 other 2.38957959825467e-13 1 2.2291763180129e-08 7.70579808891381 -2.48463152738476 0.0780256392426286 134.121013971913 174.932164590975 0.766702991902685 0.444409459560466 -372.282488648919 303.137241192407 -1.22809882145963 0.221247803430447 EHD2 other 1 1 1 0.766702991902685 -1.22809882145963 0.00301040051778195 87.4312286550658 38.2182079147394 2.28768520099413 0.0234907787310707 -209.842950073183 115.381540377066 -1.81868736877163 0.0708648281247661 DEPDC1 other 1 1 1 2.28768520099413 -1.81868736877163 1.34818907828081e-07 77.0851964364953 16.517916665855 4.66676264300582 6.60363708297927e-06 -9.80040349020814 33.1501019726986 -0.295637204925627 0.767905401854575 CCDC28A other 0.00132769660429094 1 0.0681099128738482 4.66676264300582 -0.295637204925627 0.150389830270446 1.86057321274925 48.6691586142864 0.0382289989332812 0.969555931516522 -149.737337239757 96.3457055642169 -1.55416721858924 0.122251903899304 RRAGD other 1 1 1 0.0382289989332812 -1.55416721858924 5.45067129143685e-16 121.878903560924 17.7749350849796 6.85678473525989 1.65824144924028e-10 -34.8499593216097 34.7456441764966 -1.00300225100399 0.317453825744642 HSF2 other 7.42708470171186e-12 1 2.1462619077517e-06 6.85678473525989 -1.00300225100399 0.469923525553006 -2.91069574247144 4.91539003244899 -0.592159670597137 0.554764339061255 -14.9591554170993 12.217902532482 -1.22436362357037 0.223012369627003 HSD17B6 other 1 1 1 -0.592159670597137 -1.22436362357037 0.000240472394673129 143.240581837341 37.608235078345 3.80875575625776 0.00020564594770522 -5.30252907304957 74.5370479483618 -0.0711395100691817 0.94338474842355 NR1H3 other 1 1 1 3.80875575625776 -0.0711395100691817 0.0443876206923868 750.414620854658 308.433997432374 2.4329828329615 0.0162549753416025 492.458323918395 492.385709870602 1.00014747391392 0.318989632918755 TYMP other 1 1 1 2.4329828329615 1.00014747391392 0.00100926074972257 135.270071840215 70.9887478222192 1.9055142679651 0.0587782165655026 -155.720981026815 113.427275491383 -1.37287068169635 0.172003378000404 NCAPH2 essential 1 1 1 1.9055142679651 -1.37287068169635 0.00138571283033965 213.352362817438 83.9336068317968 2.54191820023887 0.0120059818789039 -613.549535858799 368.067372327603 -1.66694899354649 0.0975439025471195 TOMM34 other 1 1 1 2.54191820023887 -1.66694899354649 7.13086569299465e-13 335.984452288999 63.725251802785 5.27239112885412 4.54855847312108e-07 -246.089391038764 132.025877856684 -1.86394815193653 0.064257831146915 SEC63 essential 9.09185375856818e-09 1 0.00508164952617087 5.27239112885412 -1.86394815193653 4.25906531257181e-19 777.452023032461 94.1045360630923 8.26157861839114 6.98625701454271e-14 -542.821146787984 264.213075058768 -2.05448252955402 0.0416644621330428 KPNA6 other 5.98569039028842e-15 1 9.62147316042822e-10 8.26157861839114 -2.05448252955402 0.0772027251439905 3950.39948370441 1763.62824398256 2.23992754549211 0.0264997381606885 8496.99092449177 6947.2016506732 1.22308108383012 0.223131751589483 VIM other 1 1 1 2.23992754549211 1.22308108383012 0.0281374540006101 -103.867966624897 41.6787208369524 -2.49211023129115 0.0137304559481117 -168.106706602688 74.4753662617732 -2.25721221714856 0.0253651836734822 FAS ts 1 1 1 -2.49211023129115 -2.25721221714856 4.34044644665858e-06 322.033949219901 378.370661578004 0.851107080757399 0.396014414666655 -2953.81440757749 790.160876672669 -3.73824431806326 0.000259656179875954 RNASET2 other 0.0371542215833974 1 1 0.851107080757399 -3.73824431806326 0.00606706613917266 -438.245107176142 224.617283129363 -1.9510747395326 0.0528397921206853 -1217.56795588692 379.794175454806 -3.20586263448847 0.0016335965888018 CD44 other 1 1 1 -1.9510747395326 -3.20586263448847 0.000450054671172661 133.947678575297 37.7163512611102 3.55144848577684 0.000507728839149197 -157.14842819074 185.268505676346 -0.848219872109671 0.397623511635833 KCNG1 other 1 1 1 3.55144848577684 -0.848219872109671 3.47554724200751e-12 139.436495216289 23.6892493055907 5.88606643535056 2.43845607564288e-08 -43.5589704800068 50.1688166771299 -0.868247915041292 0.38662740471532 AGPAT4 other 4.33852562219797e-08 1 0.000291858807693697 5.88606643535056 -0.868247915041292 0.0011331125234405 144.531949197157 52.0155333793704 2.77863053221097 0.00618200695667016 -261.522637536194 166.412370904103 -1.57153363127612 0.118238311146284 BTN3A1 other 1 1 1 2.77863053221097 -1.57153363127612 5.58229230187549e-12 120.507011927359 29.3857469258438 4.1008660501795 6.64480406495486e-05 -154.654106581296 49.0364407653265 -3.15386076492427 0.00193761092363414 MIPEP essential 6.91980953740486e-08 1 0.619428634935092 4.1008660501795 -3.15386076492427 0.064437974072001 8.17157383958091 41.2028549133724 0.198325428098644 0.843050340705749 -113.062130673214 58.5266513948031 -1.9318059034427 0.0552076177789012 PRKCH other 1 1 1 0.198325428098644 -1.9318059034427 0.000650339195204864 134.737047393269 85.1969823778813 1.58147675695435 0.115820715004643 -355.561364050818 174.593168594484 -2.03651360997209 0.0434119646932504 IFNGR1 other 1 1 1 1.58147675695435 -2.03651360997209 0.00168974475315351 119.101391950383 33.879050938399 3.51548785020397 0.000577747527704283 41.853576165505 54.7033156319237 0.765101268214173 0.445389797685268 B4GALT7 other 1 1 1 3.51548785020397 0.765101268214173 4.15106849803951e-12 144.620791170333 41.1963907339802 3.51052091199447 0.000584887158620907 -334.39709120117 83.0674936619747 -4.02560708719499 8.84293061689227e-05 VEZT essential 5.1689104937588e-08 1 1 3.51052091199447 -4.02560708719499 0.534979564595614 13.9349724778959 12.6603410798909 1.10067907254328 0.272753824393763 13.3804415057315 33.4444057142822 0.400080109661432 0.689651917617962 POU2F2 other 1 1 1 1.10067907254328 0.400080109661432 2.03890567177801e-10 215.568507931971 30.2161013819324 7.13422639165716 8.00235041411056e-11 72.0279691296277 104.293400751654 0.690628252703564 0.491132891302023 BRD9 other 2.38184960577107e-06 1 1.04566712861183e-06 7.13422639165716 0.690628252703564 7.96932852709414e-12 596.92539233342 90.2578429253967 6.61355703821565 5.74399833879024e-10 -131.239540838203 146.598722272224 -0.895229772838673 0.372052386287278 SNX1 other 9.8285728724652e-08 1 7.3057914871073e-06 6.61355703821565 -0.895229772838673 9.65030184508971e-13 186.252451476499 32.3560020656864 5.75634935052806 4.5119252293997e-08 -98.4745905417658 65.2109217673029 -1.51009352226549 0.133068645509307 TBPL1 other 1.2259743464002e-08 1 0.000533444919871927 5.75634935052806 -1.51009352226549 0.000618301635853087 19.1620875214238 5.90026286839751 3.2476667478763 0.00144367487346865 -130.965328556685 73.0024090977832 -1.79398639271293 0.074884812563034 ARNTL2 other 1 1 1 3.2476667478763 -1.79398639271293 5.67343822098733e-12 608.823934127176 87.024467285828 6.9960087446157 7.56928801769194e-11 186.902039279349 177.196224549029 1.05477438785743 0.293180517516163 BCLAF1 essential 7.0316593310917e-08 1 9.89608715433044e-07 6.9960087446157 1.05477438785743 2.74323688656974e-07 283.064220183486 112.475053076204 2.51668447750547 0.0128908465501982 -506.836173942845 161.818086193051 -3.13213551010721 0.00208461195825363 SLC39A9 other 0.00262692364257918 1 1 2.51668447750547 -3.13213551010721 0.00613609633119727 43.4451242259195 13.4780057568376 3.22340893821619 0.00164162942950523 40.9540003481807 39.1240676046269 1.04677255857051 0.297362185558881 ANK1 other 1 1 1 3.22340893821619 1.04677255857051 0.427966575127975 -11.371991576414 16.3975403522903 -0.693518133335503 0.489022412043112 9.6227938227036 24.7827421495626 0.388286080879611 0.698337119477737 IBSP other 1 1 1 -0.693518133335503 0.388286080879611 3.03017951656404e-14 35.0145841843643 7.70451220730982 4.54468540541002 1.11988429209811e-05 -54.1974131718937 15.8976336235564 -3.40914971719983 0.000835825289076727 TFB1M other 4.00347317728441e-10 1 0.113186705402356 4.54468540541002 -3.40914971719983 8.12683300529226e-22 301.131073785242 26.9888183208389 11.1576235093157 1.18045603407819e-21 -159.727981676392 143.82348221125 -1.11058346815564 0.268445673721971 RABEP1 other 1.15880511822462e-17 1 1.696787503384e-17 11.1576235093157 -1.11058346815564 8.08854634513923e-07 283.264952070019 61.8740364417019 4.57809072044158 9.96352804188317e-06 -111.985609428545 122.939049904529 -0.910903488480753 0.363847698554366 NUP160 essential 0.00743580065508649 1 0.101199554321407 4.57809072044158 -0.910903488480753 0.00281965103712654 9.18056126320776 52.1698915760896 0.175974321315542 0.860543814189373 -482.131925343068 156.591860251735 -3.07890796218909 0.0024579877057165 BAK1 other 1 1 1 0.175974321315542 -3.07890796218909 0.027613241225102 28.568602011028 19.5013164693183 1.46495761227071 0.144984353377186 -81.7054492377559 54.2313900440127 -1.5066080580167 0.133973039711936 IKZF2 other 1 1 1 1.46495761227071 -1.5066080580167 0.00036725406961944 2923.14811431313 720.442849045317 4.05743233927118 7.82096989470928e-05 -44.6053114820822 2825.35781468573 -0.0157874911454512 0.987424100871969 GRN other 1 1 0.72367434435745 4.05743233927118 -0.0157874911454512 3.77748147274233e-05 122.759324370907 38.587253170712 3.18134394868204 0.00177110200203956 -80.1937349189934 57.657518222211 -1.39086345357301 0.166260313848563 FAM13B other 0.291923768213528 1 1 3.18134394868204 -1.39086345357301 2.30312833696445e-08 39.065995525727 8.85600181617069 4.41124520259178 1.94373990330862e-05 -55.7999893469693 24.8364346504662 -2.246698857234 0.0261094707386922 CENPQ other 0.000239893847578217 1 0.191866565855594 4.41124520259178 -2.246698857234 2.95477137195122e-06 188.904840604325 97.3651575645027 1.9401687968222 0.0542603780251842 -1262.38467014834 311.071512957219 -4.05818153564563 7.9796513984723e-05 SARS essential 0.0257183300214634 1 1 1.9401687968222 -4.05818153564563 3.56362634293703e-18 322.218798527113 52.7537489537033 6.10797914684494 7.71646819016772e-09 -282.014654430693 102.161544446612 -2.76047759417017 0.00646371993845111 RANBP3 other 4.97696055054586e-14 1 9.43724059657513e-05 6.10797914684494 -2.76047759417017 9.01713839304845e-08 187.789716039908 32.9033664423416 5.70731011275038 5.5725413937216e-08 53.2606804809415 46.1460348462332 1.15417674906231 0.250181574724366 ARID4A other 0.000900721954081609 1 0.000656055298282844 5.70731011275038 1.15417674906231 1.40766251728347e-21 603.792883989951 63.5378216590532 9.50288927483114 4.05351918237407e-17 -151.019638162379 190.965950558428 -0.790819712732889 0.430273338251068 PNPLA6 other 2.00563755462549e-17 1 5.73410823538636e-13 9.50288927483114 -0.790819712732889 4.16391659965963e-11 69.8280259395014 14.6302544591501 4.77285108980654 4.31910258367305e-06 -50.3987674708987 24.0910570936328 -2.09201145782096 0.0381451072900259 IFT88 other 5.00502775279088e-07 1 0.0452771523846446 4.77285108980654 -2.09201145782096 3.40632432893307e-21 342.133360580133 30.6966981241957 11.1456078825122 1.58425639735592e-21 30.0940277017451 98.0889559728989 0.30680342555649 0.75940744501855 ALG1 essential 4.84481509304151e-17 1 2.27625959172098e-17 11.1456078825122 0.30680342555649 3.4812006513815e-10 82.912298299171 20.4777077952009 4.04890523531164 8.15042425861645e-05 -136.303663323158 45.7018271348546 -2.98245544802749 0.00332856939205422 ZCCHC8 other 4.02391983293188e-06 1 0.752773184525815 4.04890523531164 -2.98245544802749 2.47831771285486e-11 426.808529374764 59.1228692650471 7.2190090684095 2.43623751822832e-11 -34.4849666624732 187.56527387145 -0.183855816968059 0.854374874357241 ABCF2 other 3.00421673152267e-07 1 3.22460397912701e-07 7.2190090684095 -0.183855816968059 0.477307140504018 4.23702389987766 3.50435189764308 1.20907489419866 0.22846336508978 2.45697092672051 10.354096852941 0.237294566741727 0.81273962143082 LRRC7 other 1 1 1 1.20907489419866 0.237294566741727 0.000120030612443031 577.590310476751 192.843737372017 2.99512091161412 0.00320713919464319 -322.162629086628 282.6828937888 -1.13966085732561 0.256232213764256 FUT8 other 0.87202239939862 1 1 2.99512091161412 -1.13966085732561 1.51989219159582e-21 279.996738904179 29.7596237977429 9.40861150689061 7.85867241929681e-17 -52.0315635748484 61.3405137169143 -0.848241405590006 0.397646157277094 UBA6 other 2.16539040536657e-17 1 1.11003747922568e-12 9.40861150689061 -0.848241405590006 0.000158392769807425 757.948008504989 176.176019511652 4.3022200785667 3.05750023387732e-05 550.747348961929 635.313566575036 0.866890584331448 0.387405248296681 GAB2 other 1 1 0.296057747646341 4.3022200785667 0.866890584331448 4.44683944431815e-14 450.841463780845 59.2867546050266 7.60442137176151 2.63495348798987e-12 -95.8904341493812 99.7456307224904 -0.961349719830485 0.337883366255194 PIAS1 other 5.8578216000003e-10 1 3.55560623669354e-08 7.60442137176151 -0.961349719830485 1.04872730568262e-07 188.618049864994 36.4535580397046 5.17420136765673 6.99076255966508e-07 -25.0064782848163 80.2835628219863 -0.311476937567699 0.755856615997684 SLC4A7 other 0.00104182528058968 1 0.00771151017956654 5.17420136765673 -0.311476937567699 6.78872469947404e-06 222.261972947707 43.9472974965639 5.05746622906868 1.19364364095445e-06 161.658106812776 64.6270644756398 2.50139950072636 0.0134159607527007 APBA2 other 0.0569438227791882 1 0.0129832618826616 5.05746622906868 2.50139950072636 0.00120836645071585 179.904403039129 81.9809391114411 2.19446623799437 0.0296709133364694 -377.825905034907 199.752550655054 -1.89146973991517 0.0604032886492959 MAP2K3 other 1 1 1 2.19446623799437 -1.89146973991517 4.12926966891107e-08 50.0459462548841 8.44638355800166 5.92513303607592 2.01105770525029e-08 -25.4216269016544 33.4846775356403 -0.759201783400667 0.448907615524183 ASTE1 other 0.000422589457916359 1 0.000241648693862875 5.92513303607592 -0.759201783400667 1.44919738333249e-05 308.279495686795 64.6809833102401 4.76615351081079 4.35421855025877e-06 130.45737036686 279.976591562774 0.465958134709307 0.641912485937828 RNF19A other 0.117645843578931 1 0.0456104393139606 4.76615351081079 0.465958134709307 4.84278570318657e-21 124.279629560126 15.9451447890117 7.79419887399024 9.25592209545079e-13 -77.6065061552319 32.2959045921864 -2.40298289009709 0.0174594137639287 PEX3 other 6.88111420565779e-17 1 1.25778725355081e-08 7.79419887399024 -2.40298289009709 1.40057314737462e-12 487.918480230406 91.5629084219256 5.32877874501384 3.45391044468131e-07 -188.900810075122 161.664873744928 -1.16847157764875 0.244422247238058 GABARAPL2 other 1.77102474485521e-08 1 0.00388495846817754 5.32877874501384 -1.16847157764875 3.53503002733421e-05 165.416572504709 64.8414158316855 2.55109439519481 0.0117824113992792 -515.870885122411 186.712164223025 -2.76292060171404 0.00647687425448511 SH3YL1 other 0.274530431922775 1 1 2.55109439519481 -2.76292060171404 0.00290631289995572 776.676847709841 381.34688666062 2.03666759813106 0.043515726503036 -1582.85825887296 867.381162899183 -1.82487045670017 0.0700930696412781 VCL other 1 1 1 2.03666759813106 -1.82487045670017 0.0253948345741837 27.9356831778657 40.9063795415608 0.682917517779424 0.495691724147684 -87.339818261276 59.6064991870006 -1.46527340898295 0.1448983071421 DEPDC1B other 1 1 1 0.682917517779424 -1.46527340898295 0.836508832448677 23.1772847972048 38.9503333189535 0.595047149081176 0.552679673515865 19.6374519759913 63.7017332213285 0.308271862992518 0.758289372227962 DAPK2 other 1 1 1 0.595047149081176 0.308271862992518 6.40783824307144e-13 299.36802215369 48.0142244796443 6.23498609835109 4.14672947228162e-09 -290.18412601856 149.199143033571 -1.94494499176357 0.0536033383039248 ADSS other 8.18216865257792e-09 1 5.12494295479285e-05 6.23498609835109 -1.94494499176357 0.585871362756532 499.340529100532 505.424753368705 0.987962156131806 0.324691327207903 669.206613756632 2044.63720245386 0.327298463000422 0.743878148585344 TIMP2 other 1 1 1 0.987962156131806 0.327298463000422 4.51332676767903e-13 322.19821958457 51.6064749573449 6.24336810159737 3.97316773813669e-09 -60.8526706231454 90.2105597411851 -0.674562609939815 0.50096509508551 RFC1 other 5.79150090828573e-09 1 4.91361654175365e-05 6.24336810159737 -0.674562609939815 2.79736216389592e-11 141.750853567255 21.046157632778 6.73523671354087 3.11427281574181e-10 -170.891777520978 93.3733023569473 -1.83019956676367 0.069166144296258 TBC1D23 other 3.38480821831406e-07 1 3.99218632249942e-06 6.73523671354087 -1.83019956676367 1.66103829895284e-13 366.416244207382 56.2070521141515 6.51904397090999 9.71010448705945e-10 -253.119739993158 128.640436101844 -1.96765299981387 0.0509159872019971 CUL3 essential 2.1555294005511e-09 1 1.22599779253613e-05 6.51904397090999 -1.96765299981387 0.00087723335561727 0.359272081799131 5.02062212011981 0.0715592755645503 0.943059343605334 -25.4425235084425 9.49340911832011 -2.68001970539163 0.00828559728413624 MYOM2 other 1 1 1 0.0715592755645503 -2.68001970539163 0.753322712564848 1.47111650485437 3.09608199257582 0.475154246038058 0.635359092138215 3.61966019417475 4.95724821461202 0.730175298365214 0.466406907625244 CYP46A1 other 1 1 1 0.475154246038058 0.730175298365214 4.46342823326212e-15 340.617433985236 44.5769708804741 7.64110766742197 2.0435170187686e-12 -295.074758389772 132.753191437632 -2.22273193732145 0.0276718984827894 ZZZ3 other 5.99349143162437e-11 1 2.76120019576013e-08 7.64110766742197 -2.22273193732145 5.57054322922565e-05 47.5579352092922 12.8316882578847 3.7062882337458 0.000294033345548843 -39.3217675175922 36.2171985894698 -1.0857208466981 0.279321407918219 USP2 other 0.421634417020089 1 1 3.7062882337458 -1.0857208466981 5.46423308409391e-09 110.281199021207 16.959119314934 6.50276685795206 1.04190963759928e-09 -12.6802610114192 66.9095059188608 -0.189513595075656 0.849939852507459 TUBG2 other 5.91609878638861e-05 1 1.31405643494021e-05 6.50276685795206 -0.189513595075656 0.127749901280208 51.0722336173904 31.5029013626332 1.62119142708453 0.10703564618964 -28.4644943012411 52.5668029470622 -0.541491829546996 0.588956255832244 RPL26L1 other 1 1 1 1.62119142708453 -0.541491829546996 0.385235209482939 -22.6723809765506 49.7641479804406 -0.455596687508079 0.649352289232886 -113.030811592732 82.3872672668662 -1.37194514810894 0.172170627682362 FLT4 other 1 1 1 -0.455596687508079 -1.37194514810894 3.94178731520414e-11 321.271076695385 44.7057502597333 7.18634794917548 2.73822180526161e-11 -57.0389379283615 183.568800985092 -0.310722397391448 0.756434569697924 NSUN2 other 4.74472939131122e-07 1 3.61992922655585e-07 7.18634794917548 -0.310722397391448 2.59901497525644e-21 252.653688371523 34.0902882078495 7.41130983789536 8.28961118517394e-12 -222.437235387093 76.5693554577894 -2.90504254681517 0.00422416437971904 FBXO42 other 3.69891811278497e-17 1 1.10649730099702e-07 7.41130983789536 -2.90504254681517 0.059088424020548 46.4388750887153 20.0567650432031 2.31537214444524 0.0219212664764809 13.2411983568832 30.0937358331337 0.439998491058208 0.660559125055518 MFAP3 other 1 1 1 2.31537214444524 0.439998491058208 1.34386021630559e-16 188.80213707111 22.7622693103466 8.29452171472598 5.77842777295061e-14 -366.268937774197 161.100640166113 -2.27354116902659 0.0244128754782138 MRI1 other 1.84485130494431e-12 1 7.96267347112594e-10 8.29452171472598 -2.27354116902659 1.1607481107931e-19 162.224746518913 15.8446518334337 10.2384544781605 9.11426705747631e-19 -67.7814948740044 51.6966418756486 -1.31113922326031 0.19192698765406 METTL1 essential 1.63677091102935e-15 1 1.29923876904325e-14 10.2384544781605 -1.31113922326031 0.832236308189354 -2.68584139695249 4.63747906528556 -0.57915978900211 0.563405473714914 -4.66561227894561 13.2145076759809 -0.353067431140545 0.724565168599321 HOXC8 other 1 1 1 -0.57915978900211 -0.353067431140545 1.12070274442637e-06 108.042462206413 27.777170856057 3.88961362430665 0.000148993888201146 -12.5222969085107 43.8075711611684 -0.285847778742196 0.775378846880646 AGA other 0.0101815844331136 1 1 3.88961362430665 -0.285847778742196 5.54562553343169e-05 56.1865857752624 16.5833724321519 3.38812783739499 0.000896264088108418 -13.9015538823078 30.1218722864928 -0.461510285618651 0.645092317689538 PI4K2B other 0.419803852880779 1 1 3.38812783739499 -0.461510285618651 3.31011720617187e-17 607.268053855568 68.5809302173437 8.85476548555175 2.20647449696704e-15 196.515081875634 128.835953975203 1.52531242880739 0.129286888436555 BOD1L1 other 4.57623703753261e-13 1 3.08619587890779e-11 8.85476548555175 1.52531242880739 1.68477512294208e-06 404.875919615658 107.543271098219 3.76477222127532 0.000238747223310975 -326.154146247486 176.486844932694 -1.8480365852303 0.0665663424513429 MAT2B other 0.0150551504986104 1 1 3.76477222127532 -1.8480365852303 0.288076916696541 -6.49367600930892 4.20863023886038 -1.54294286757472 0.124857861468443 -8.06936152989982 6.36750942702902 -1.26727123412597 0.206934824941751 TLL1 other 1 1 1 -1.54294286757472 -1.26727123412597 1.77846479413071e-17 742.999757572085 99.1528261417489 7.49348038259537 6.2348116405357e-12 70.0704354106376 158.167026702662 0.443015443050357 0.658419375195471 EDC4 essential 2.46673066945929e-13 1 8.34903626784135e-08 7.49348038259537 0.443015443050357 2.4270510760967e-07 545.462487446947 96.7881966628408 5.63563023440814 8.39072979054972e-08 -33.2959075215703 404.471781436572 -0.08231948197551 0.934502408011358 TRIO other 0.00233579395563546 1 0.000978373077068056 5.63563023440814 -0.08231948197551 0.416317966790302 -484.760194552529 485.576402464582 -0.998319094774972 0.319690700070486 -56.8524591439689 705.815914591801 -0.080548565098378 0.935905555024948 VCAN other 1 1 1 -0.998319094774972 -0.080548565098378 1.66554560343545e-15 450.930773411434 51.7878816316153 8.70726430980624 4.36388910360857e-15 218.305613007443 114.144578093716 1.91253598421651 0.0576517904633939 CLEC16A other 2.25348320144817e-11 1 6.08980724408576e-11 8.70726430980624 1.91253598421651 0.172126260237081 -61.2142997026018 79.7401184308824 -0.767672545604024 0.443864866300236 110.502113211672 158.088839978366 0.698987437865913 0.485621081118151 MSR1 other 1 1 1 -0.767672545604024 0.698987437865913 2.18584053345888e-13 2667.82069117001 440.850978600302 6.05152493851849 1.08520992281817e-08 67.5259188753847 714.193500740079 0.0945484925379625 0.924798811301275 CDH1 ts 2.82694756192236e-09 1 0.000131885561920093 6.05152493851849 0.0945484925379625 6.60490283906961e-22 307.937922127734 49.8316220996904 6.17956849792467 5.56399691946197e-09 -305.365440511079 79.7515528430693 -3.82895918167211 0.000187234164222244 SKIV2L2 essential 9.4218938999328e-18 1 6.84315981124628e-05 6.17956849792467 -3.82895918167211 0.11781461496155 11.828751828409 9.77442910249667 1.2101731675958 0.228091033395988 -58.5362843167595 42.3939314500449 -1.38077036770548 0.169376462876152 DNAH5 other 1 1 1 1.2101731675958 -1.38077036770548 3.93483207761372e-10 166.244083174582 41.8381301065292 3.97350652983983 0.000108235508378434 -83.0638823415451 58.8148057682317 -1.41229544596084 0.159867582266953 ZFYVE16 other 4.53725486869638e-06 1 0.985809010310778 3.97350652983983 -1.41229544596084 2.6988902614003e-07 507.424186778594 131.842803516246 3.84870598353189 0.000179880870836093 -88.8367561085289 206.634364889011 -0.42992246791208 0.667913051145071 RIPOR1 other 0.00258607664847376 1 1 3.84870598353189 -0.42992246791208 0.588869529897524 -10.7846792397874 12.2911612576376 -0.877433711406711 0.381635849018242 -35.2491929415762 51.9117822685875 -0.679021050735643 0.498157139902502 C6 other 1 1 1 -0.877433711406711 -0.679021050735643 0.00121039495030172 308.54444535294 84.6318064474999 3.64572680537477 0.000363455640832515 495.277156855962 346.783454403117 1.42820296230232 0.155245313713362 RAI14 other 1 1 1 3.64572680537477 1.42820296230232 0.0510967743604177 11.3590216173482 4.99545975880729 2.2738691063063 0.024364593890164 1.84178642622601 7.98063109028984 0.23078205287135 0.817792435752428 SOX30 other 1 1 1 2.2738691063063 0.23078205287135 4.43727711273803e-12 378.962257276351 78.8010745418622 4.80910012305774 3.52550231233218e-06 -296.560422649921 137.024254571134 -2.16429145028457 0.0319533105984246 PNKP essential 5.51952900053484e-08 1 0.0371693708789181 4.80910012305774 -2.16429145028457 2.50992246255904e-06 65.5840478957874 21.0613732681161 3.11394926916149 0.00219926489297082 -31.0653523103575 33.3662551080106 -0.931041023626873 0.353280200171727 PHLPP2 other 0.0220346092988058 1 1 3.11394926916149 -0.931041023626873 0.020365221436545 72.9719963301221 25.8484144718223 2.82307436727579 0.00539379197094299 35.381437924851 43.0753641171135 0.821384534989787 0.412713721964609 SPDL1 essential 1 1 1 2.82307436727579 0.821384534989787 1.34936103120844e-08 189.322306261624 34.3599855752745 5.50996466069127 1.57959705708889e-07 -98.0986608803474 115.47720449508 -0.849506717012078 0.396990230645208 STAU2 other 0.000142802877932789 1 0.00181590477682939 5.50996466069127 -0.849506717012078 1.25135133026592e-09 117.489140190271 27.5786444379362 4.26014920547208 3.54326850949364e-05 -104.511577813678 60.8895508932986 -1.71641236107689 0.0880973140087666 PQLC2 other 1.40539267902165e-05 1 0.340578969132529 4.26014920547208 -1.71641236107689 9.59293237581858e-23 176.808597218112 14.9627569923348 11.8165788102212 2.04035516877453e-23 20.95787708395 83.9942364487574 0.249515656907433 0.803290175413953 CTNS other 1.37217304703709e-18 1 2.94260022440662e-19 11.8165788102212 0.249515656907433 0.00697218001722815 232.913097583739 76.1859171615389 3.05716733828758 0.00267708159347119 96.1834837014759 117.402481212883 0.819262784804935 0.414028972811251 RTN4R other 1 1 1 3.05716733828758 0.819262784804935 4.68714012161147e-21 296.359747610652 28.0812248535645 10.5536617136924 9.20382907781676e-20 -239.012696792551 147.256107920274 -1.62310888266825 0.106694258081681 PHF23 other 6.66042611280989e-17 1 1.31715997932636e-15 10.5536617136924 -1.62310888266825 1.54833635870821e-26 229.307890668443 17.8925088505297 12.8158601224699 9.11118267139432e-26 -108.687682173432 84.4970805558893 -1.28628920027057 0.200350734144494 INPP4A other 2.23672670378988e-22 1 1.31711256697676e-21 12.8158601224699 -1.28628920027057 0.00907253275603604 -21.0664972292821 14.8975514538564 -1.41409125483026 0.159380088277442 -81.46052247823 27.6874943073992 -2.94214137161774 0.00377047633111654 RAB27B other 1 1 1 -1.41409125483026 -2.94214137161774 4.80752981479312e-06 446.807367577614 126.723827181077 3.52583549216175 0.000557278535709819 -472.85056366921 227.327210032284 -2.08004384341873 0.0391891373124891 PSMA4 other 0.0409313088431486 1 1 3.52583549216175 -2.08004384341873 9.34119050092824e-16 311.938288689689 33.4991019810928 9.31184032532425 1.17272132702936e-16 129.055632122278 124.767518253534 1.03436883195858 0.302574898448887 LSG1 essential 1.26825343431103e-11 1 1.65447524817302e-12 9.31184032532425 1.03436883195858 0.00011535067885998 -3.70292682926835 37.3597419885664 -0.0991154283239321 0.92118739670751 -341.165889792231 85.3415169590886 -3.99765438849395 0.000102746358101537 PARP3 other 0.840214344816096 1 1 -0.0991154283239321 -3.99765438849395 0.983298400272499 -10.3858714813643 293.43377440276 -0.035394260604469 0.971810322224499 -83.0802272994376 474.616010764265 -0.175047249597954 0.86126805201765 TNC other 1 1 1 -0.035394260604469 -0.175047249597954 2.70912696443389e-16 244.360253938806 40.8635990869103 5.97990043459194 1.6039034821895e-08 -273.002185406893 92.2077501090811 -2.96072927800464 0.00357584908965935 THAP3 other 3.70689842543489e-12 1 0.000193414011357783 5.97990043459194 -2.96072927800464 0.343377366723694 3.58373158737221 9.33066161526312 0.38408118685924 0.701451530417982 -55.760874213364 44.9958252557028 -1.23924550547713 0.217152203082948 RIPOR3 other 1 1 1 0.38408118685924 -1.23924550547713 1.8298143389298e-09 182.968598494514 31.9138739520199 5.73319925903054 5.00311991390691e-08 -49.9584715488647 55.141306673288 -0.906008119192176 0.366337784692173 TDP1 other 2.03713230353055e-05 1 0.000590618305836711 5.73319925903054 -0.906008119192176 0.000706006381040576 80.4314208882544 24.4905992891097 3.28417528451499 0.0012628190289752 -31.6705652558725 53.0116390153734 -0.597426637699091 0.551088765387733 AIFM2 other 1 1 1 3.28417528451499 -0.597426637699091 2.05369821325706e-08 32.2900598202969 9.76578785210328 3.30644698710535 0.00117744423789558 -58.4128912336221 16.9646058987492 -3.44322123262109 0.000741657946123957 SPATA7 other 0.000214796296124556 1 1 3.30644698710535 -3.44322123262109 1.11098306349464e-10 108.743721755048 22.7715374625685 4.77542291265136 4.12119854104882e-06 -188.723292431783 63.7395145877868 -2.96085236375403 0.00355076075239633 MED17 essential 1.31340417766336e-06 1 0.0432396150926843 4.77542291265136 -2.96085236375403 0.000102300544127357 364.423779083635 110.471173024584 3.29881333841306 0.00120287891235091 -103.286774512466 227.38109333225 -0.454245218891364 0.650283722959845 AP2S1 essential 0.749658387365272 1 1 3.29881333841306 -0.454245218891364 0.360283455519189 -3.85118431000439 5.5430449857921 -0.694777747587423 0.488228099460343 -24.0647509271222 16.8652317317047 -1.42688528150391 0.155611385599083 USH2A other 1 1 1 -0.694777747587423 -1.42688528150391 0.869315404150679 -1.51153455197013 4.15725199862096 -0.363589831088309 0.716666223479367 -11.5946798063505 25.6402883530979 -0.452205515268693 0.651761406200191 TG other 1 1 1 -0.363589831088309 -0.452205515268693 0.154421276688202 -13.9595026267855 115.573773044923 -0.120784346301123 0.904019295705822 -295.728867651675 210.032891328997 -1.40801217266701 0.161142943091277 ADAM28 other 1 1 1 -0.120784346301123 -1.40801217266701 0.251279965755937 105.924151833917 63.4513340861687 1.6693762764715 0.0970613035318568 99.3552322642585 176.633077911282 0.562495051544998 0.57459139358217 BARX2 other 1 1 1 1.6693762764715 0.562495051544998 2.39238872639263e-09 192.9389917019 28.7539939003032 6.70998931038466 3.61787547231357e-10 -13.6231729172773 122.512858814422 -0.111197902400704 0.911606112195851 DCUN1D1 other 2.64622117026289e-05 1 4.62726272908906e-06 6.70998931038466 -0.111197902400704 3.13251006596654e-05 158.809777662203 96.6673521509445 1.64284811912738 0.102415672339625 -479.134551207038 160.00807315083 -2.99443985401529 0.00319545285376395 JADE2 other 0.244930962057924 1 1 1.64284811912738 -2.99443985401529 0.0294967354124465 249.10532375021 93.4683695149847 2.66512965875878 0.00852731063768575 278.502554344785 192.296368095074 1.44829856696559 0.149593218309491 ZIC2 other 1 1 1 2.66512965875878 1.44829856696559 0.494788959388674 -8.70027179205697 45.4081745253466 -0.191601443638756 0.848310123920623 76.4453051684756 74.9927986017822 1.01936861397061 0.309647735681743 LCP2 other 1 1 1 -0.191601443638756 1.01936861397061 1.67154124497446e-22 162.966000487448 14.5134942204479 11.2285847923409 1.39071077135691e-21 -191.346478186693 104.12400181563 -1.83767887182732 0.0681015416009281 TRIT1 other 2.3886324390685e-18 1 1.99845137843988e-17 11.2285847923409 -1.83767887182732 7.14390329028843e-19 1092.83028100098 116.209755700686 9.40394611804982 9.79175670399081e-17 -109.408211007037 352.609328756704 -0.310281668930341 0.756786242074224 CUL7 other 1.00250394872618e-14 1 1.38240021146942e-12 9.40394611804982 -0.310281668930341 2.33550539732467e-07 1578.69428061319 421.504110520208 3.74538288289719 0.000255122632581153 -1235.12112294526 611.31877305265 -2.02042073201453 0.0450959393732535 CTNNA1 ts 0.00225212785464018 1 1 3.74538288289719 -2.02042073201453 9.83984707251326e-10 79.8688964666616 15.1980813938052 5.25519599462182 4.88846567184318e-07 -33.4548284118117 35.5683271910272 -0.940579190922742 0.348403187841764 CNTLN other 1.11131232836965e-05 1 0.00545308345694107 5.25519599462182 -0.940579190922742 0.229141876716466 -10.8636706948641 6.39326998897766 -1.69923540122561 0.0916126628683608 -7.42451249656693 15.6638992432411 -0.47398878026942 0.636285105648067 EPHA3 other 1 1 1 -1.69923540122561 -0.47398878026942 0.00871330114018369 2725.21086636023 905.501431394383 3.00961519427272 0.00304841270228124 1146.97636805132 1311.31699154105 0.874675136103749 0.383086761231845 HSPA5 essential 1 1 1 3.00961519427272 0.874675136103749 1.14184266092081e-14 889.717967178401 124.090651443606 7.16990326690918 3.18338674297696e-11 -980.359446537749 501.954781813053 -1.95308319007682 0.0526709079006411 DSG2 other 1.52093442434651e-10 1 4.20175216205529e-07 7.16990326690918 -1.95308319007682 0.0922811196113945 35.8986218962845 45.9884124199561 0.780601460395417 0.43627530459962 -256.225359153369 157.703896263074 -1.62472434242174 0.106334790220823 PREX2 other 1 1 1 0.780601460395417 -1.62472434242174 4.0367702763818e-18 175.88451279663 18.1883535810512 9.67017228980349 1.71519249183285e-17 46.013833908423 66.7925527153288 0.688906652580488 0.491946205154446 WDR37 other 5.63412027474607e-14 1 2.43111383792388e-13 9.67017228980349 0.688906652580488 4.92186159990911e-11 120.687142843926 28.5503161502972 4.22717360496443 4.04147302333423e-05 -96.5681869346793 42.7788908840846 -2.25737939761796 0.0253903742494694 YTHDC2 other 5.89835894133108e-07 1 0.385596941156319 4.22717360496443 -2.25737939761796 1.46568271714492e-13 846.578519855596 147.829594982331 5.72671879373532 5.4137255945889e-08 -408.928204855952 255.917079339061 -1.59789337199401 0.112171138828694 POLR2B essential 1.90450812265811e-09 1 0.000637845149554465 5.72671879373532 -1.59789337199401 1.98927725964164e-12 215.357973990417 33.6808857705638 6.39407097121639 1.85721839795622e-09 -82.9561348689106 50.2383366243271 -1.65125162262519 0.100738275867205 FAM214A other 2.50211293717725e-08 1 2.32412310320241e-05 6.39407097121639 -1.65125162262519 2.5259718595357e-05 36.911499911093 31.8170868876603 1.16011563350913 0.24779710594677 -168.330861089534 55.7895217045871 -3.01724868660585 0.00298547339362251 ARAP2 other 0.200107490712418 1 1 1.16011563350913 -3.01724868660585 0.0235747642514728 1724.01990893836 703.943960206322 2.4490868682687 0.015458459672444 -3233.64367504072 2868.37999682111 -1.12734145358161 0.261374604986946 CP other 1 1 1 2.4490868682687 -1.12734145358161 1.9186658567958e-06 199.107150008344 45.9622284682782 4.33197337561127 2.66331937949882e-05 -70.0532871683632 96.3015362929488 -0.727436859940234 0.468070050433247 KIAA0556 other 0.0170492648034874 1 0.25948720714457 4.33197337561127 -0.727436859940234 1.01754451831911e-06 55.3403697180002 13.5525195425748 4.08340084248912 7.13226226923323e-05 -55.5079363484004 37.6307792161114 -1.47506741833916 0.142249265259194 DTNBP1 other 0.00927898846255194 1 0.662587164811767 4.08340084248912 -1.47506741833916 4.54991685430716e-09 39.2550724974261 6.57633922303557 5.96913741309506 1.56578575240402e-08 -21.801063656843 29.6900798646075 -0.734287807788327 0.463882700255559 ANO2 other 4.95131790661e-05 1 0.000188912051027545 5.96913741309506 -0.734287807788327 2.78981573791833e-13 68.349149876627 9.67787388426128 7.06241377951622 5.18233505645871e-11 -79.7094621932064 44.4232891016096 -1.79431698564432 0.0747115984108726 C12orf4 other 3.59830433876706e-09 1 6.80596062964723e-07 7.06241377951622 -1.79431698564432 1.67909701704767e-11 106.74942627549 17.530596325929 6.0893208816633 9.08979202142244e-09 1.13682934943878 32.1394265975366 0.0353717993688761 0.971830298983143 FAM184B other 2.04833045109645e-07 1 0.000110840923909225 6.0893208816633 0.0353717993688761 2.11890421220067e-09 1685.6840367077 309.168098554131 5.4523220364295 2.52002500208464e-07 -1055.10766515141 699.601002316764 -1.50815630860643 0.134017870039606 MAP4 other 2.35219556596396e-05 1 0.00285871636236481 5.4523220364295 -1.50815630860643 1.35781871827067e-18 264.241625262998 34.2606156614678 7.71269342833745 1.32987431645434e-12 -42.0090052979796 71.2926253301024 -0.589247556861142 0.556542152432633 GOPC other 1.90162511493807e-14 1 1.80211268622728e-08 7.71269342833745 -0.589247556861142 0.385238265602076 -19.0737819716609 22.8958921697233 -0.833065679654249 0.406073210366779 16.1399211640321 47.6438683467773 0.338761769857921 0.735241845537822 ROS1 og 1 1 1 -0.833065679654249 0.338761769857921 2.74711902778214e-10 345.288102624165 61.7240397173907 5.59406196038203 1.0142712355556e-07 -160.796404039125 163.416898592884 -0.983964360012196 0.326707009230757 USP28 other 3.19050403886618e-06 1 0.00117817746722139 5.59406196038203 -0.983964360012196 0.000245655367329605 109.959433704965 43.6580493020242 2.51865201178072 0.0127946968708389 -124.136009259752 100.736941351454 -1.2322789196732 0.219710892775865 HDAC9 other 1 1 1 2.51865201178072 -1.2322789196732 0.0387398255853944 205.071998100869 79.5743638507711 2.57711137327404 0.0109206609414059 134.200970122954 129.804735389372 1.03386806128756 0.302850812281029 TSPAN17 other 1 1 1 2.57711137327404 1.03386806128756 5.42950923099107e-05 382.216763447434 128.182169868164 2.98182472523709 0.00333505147785616 -411.233426872638 206.694693602983 -1.98956934841555 0.048420698411861 NOP16 essential 0.411556799709123 1 1 2.98182472523709 -1.98956934841555 0.000281876116340328 41.295364068319 33.0303926938176 1.25022322474684 0.213177964032825 -152.271982608377 62.1086827692484 -2.45170201361557 0.0153740468289061 CC2D2A other 1 1 1 1.25022322474684 -2.45170201361557 0.00029341417261412 119.841833846928 32.1205314772324 3.73100407544234 0.000268829616850206 -77.0957486950504 142.357204627444 -0.54156548589735 0.588910803019766 RRM2B other 1 1 1 3.73100407544234 -0.54156548589735 3.21262510490918e-05 72.7268531111688 18.0855413036374 4.02127046628911 9.04000744101226e-05 -71.3563637207085 59.4030091323477 -1.20122473192779 0.231508229471139 ZNF800 other 0.250841768191309 1 0.831228684201077 4.02127046628911 -1.20122473192779 1.67447587798474e-07 198.415790929203 39.5028371455805 5.02282380878057 1.37799410590786e-06 0.6831390401633 89.1576242220635 0.00766214943616955 0.9938963387477 SNX29 other 0.00163629782796669 1 0.0149305661375116 5.02282380878057 0.00766214943616955 0.334462774345411 162.906931885954 110.076069761146 1.47994865949925 0.141041546908315 284.142250658366 422.870556421392 0.671936710521924 0.502685881887871 LMO3 other 1 1 1 1.47994865949925 0.671936710521924 1.16363645364718e-21 143.206317210344 14.4839532469644 9.88723967611246 4.38451610105918e-18 -363.911968499106 96.3011033070352 -3.7788971881127 0.0002262060900644 MRPS10 essential 1.65841467373796e-17 1 6.23390499248594e-14 9.88723967611246 -3.7788971881127 5.78989752201233e-08 323.640482571805 56.3470889769002 5.74369481100405 5.03655077883871e-08 -145.440735538612 208.81336798611 -0.696510654185159 0.487194234238695 RSF1 other 0.000586574517955069 1 0.000594464088426333 5.74369481100405 -0.696510654185159 7.21696160547043e-09 220.194248412873 51.7058442909938 4.25859496991576 3.56536528594169e-05 -269.358665521741 134.786292554044 -1.99841289806037 0.0474320576274845 VPS13D essential 7.76039881436235e-05 1 0.342453335714699 4.25859496991576 -1.99841289806037 0.48936909064193 29.946923094514 26.243306223702 1.14112615381773 0.255566145174229 0.866671240290602 131.435559542034 0.00659388709806067 0.99474730213415 CELF2 other 1 1 1 1.14112615381773 0.00659388709806067 5.84530808471322e-05 273.92168342044 272.766109192357 1.00423650222348 0.316839941145851 -1356.90603319 423.654213630338 -3.20286212088516 0.00165360128869095 FAM120A other 0.441437666557542 1 1 1.00423650222348 -3.20286212088516 8.58829754636627e-08 233.076672921909 54.546732816001 4.272972199969 3.36590622548759e-05 -329.057683285708 135.939706849197 -2.42061492490008 0.0166577906504154 R3HDM1 other 0.000859516818440337 1 0.324136769514455 4.272972199969 -2.42061492490008 1.10681454729788e-09 689.222478238608 101.624191873143 6.78207093739019 2.51115251991812e-10 127.136947431302 749.14581389425 0.169709214245505 0.865465978956558 COL9A2 other 1.24638386171214e-05 1 3.23034660162266e-06 6.78207093739019 0.169709214245505 0.641973531416495 -11.520138482982 14.6154191668965 -0.788218138079459 0.43182134375685 -26.5753473315049 30.5357676969161 -0.8703022499804 0.385535190727628 KITLG other 1 1 1 -0.788218138079459 -0.8703022499804 1.58048915047239e-13 17.5351237303937 9.80059788262125 1.78918918421166 0.0755626344252309 -64.9895242145205 13.9753507172068 -4.65029647767649 7.1152355988712e-06 ERCC8 other 2.05179101514326e-09 0.103427064665192 1 1.78918918421166 -4.65029647767649 0.0211729538532538 12.0258868187967 12.9306633160091 0.930028609120752 0.353821332723402 -21.9425673022382 17.9506954225215 -1.22237979007256 0.223443787435062 ADAMTS6 other 1 1 1 0.930028609120752 -1.22237979007256 1.86026122838607e-08 890.756259204716 217.393865207455 4.09743052479739 6.75394495346684e-05 -698.68654884634 466.655219075524 -1.49722218950103 0.136395601606545 H6PD other 0.000195197210694551 1 0.629265051314505 4.09743052479739 -1.49722218950103 9.39230613998653e-09 344.324373854614 98.4791652980974 3.49641848417724 0.000617333356536604 -541.334880879657 215.403577854174 -2.51311926325631 0.0130025091862114 VAMP3 other 0.000100319221881196 1 1 3.49641848417724 -2.51311926325631 0.000419894204529709 148.599022602322 61.3524842412345 2.4220538816006 0.0166021338602583 -175.218350641417 134.19635083015 -1.30568640322559 0.193619079338375 PER3 other 1 1 1 2.4220538816006 -1.30568640322559 0.00391107756069896 18.8676847892488 10.3942801870232 1.81519878719492 0.0714517226605225 -30.419218081857 22.7354195654095 -1.3379659871392 0.182892729497528 UTS2 other 1 1 1 1.81519878719492 -1.3379659871392 0.950820869434702 -0.461148442272464 6.25982960435937 -0.0736678905686696 0.941370872157632 -4.06056200366527 13.6921316245411 -0.296561712596111 0.76720333593643 TNFRSF9 other 1 1 1 -0.0736678905686696 -0.296561712596111 0.00762051135187243 325.14625426575 114.424620097406 2.84157599989376 0.00508533120905238 -540.235746980124 458.908408289619 -1.17721910782506 0.240889634588076 EPN3 other 1 1 1 2.84157599989376 -1.17721910782506 0.522554494743012 148.806324375103 130.385114248537 1.14128307692742 0.255523731238452 107.31838467521 528.71728240186 0.202978771920757 0.839419560769935 LTBP1 other 1 1 1 1.14128307692742 0.202978771920757 0.848859909675257 -49.0744129834253 147.826137126384 -0.331973857515258 0.74038186042618 -315.387383852336 607.718061338844 -0.518969903835862 0.604562146955969 ELN other 1 1 1 -0.331973857515258 -0.518969903835862 0.136343880708313 36.7815584415584 32.2469345023611 1.14062186093581 0.255882221508002 -187.954805194805 132.421907367568 -1.41936337371348 0.157910133759435 RFC2 essential 1 1 1 1.14062186093581 -1.41936337371348 5.59508368059807e-21 1038.35348073767 110.060756448595 9.43436620138664 6.42299685702789e-17 127.027601300249 235.035873842104 0.54046048045238 0.589670561612595 ARID1B other 7.9472568599215e-17 1 9.07826375772322e-13 9.43436620138664 0.54046048045238 1.22490691059809e-10 796.336803185438 114.79878453811 6.9368051795102 2.06823954875741e-10 -73.3007015548005 398.379493306558 -0.183997175523276 0.85432114804558 CLPTM1L other 1.44502268243257e-06 1 2.66947678558119e-06 6.9368051795102 -0.183997175523276 4.29149268055982e-15 356.008697776173 68.6868818428124 5.18306681311997 6.71335600879717e-07 -149.140237038295 128.191085612064 -1.16342128102127 0.246446491420214 NEDD4L other 5.76433296852795e-11 1 0.00741355904051472 5.18306681311997 -1.16342128102127 0.000122175598775043 -13.6096884167124 141.198713772467 -0.0963867733146888 0.923339534233286 -632.231392654843 200.783075188707 -3.14882811741298 0.00197147753341188 HEXB other 0.886586532529255 1 1 -0.0963867733146888 -3.14882811741298 3.2130907883739e-14 78.6261507479863 20.040320046188 3.92339795805518 0.000132214641787144 -80.6130789700806 28.6495983621545 -2.81375947931503 0.00554887394128059 PTCD2 other 4.24288638604774e-10 1 1 3.92339795805518 -2.81375947931503 2.07827408492775e-05 88.7291140519244 50.7958146026721 1.74678002008568 0.0826310929348415 -216.446522375998 71.4279316485749 -3.03027845522552 0.00285820462201515 JKAMP other 0.166074882126576 1 1 1.74678002008568 -3.03027845522552 0.00451615583244203 276.884873515746 91.0068078305289 3.04246330704573 0.00276227614961533 101.173276903788 142.523117141554 0.709872748596307 0.478863547037455 DKK3 other 1 1 1 3.04246330704573 0.709872748596307 0.00371087751143413 -17.1433260393877 52.198415684745 -0.328426175670267 0.743050555337977 -326.860545362734 110.951283994996 -2.94598253930506 0.00373710104288513 NFE2L3 other 1 1 1 -0.328426175670267 -2.94598253930506 2.39450414900685e-11 252.256442100313 46.4434561683363 5.43147437576564 2.17098696097304e-07 -305.97474778449 130.826788416428 -2.33877748959607 0.0206491452808163 MCUR1 other 2.90405463191551e-07 1 0.00247297124724439 5.43147437576564 -2.33877748959607 0.33203194629971 -21.0870504272701 59.5615659372688 -0.354037878209571 0.723794762317871 -223.234685209005 151.697485040993 -1.47157802351621 0.143175404225672 LIMA1 other 1 1 1 -0.354037878209571 -1.47157802351621 2.38539009816122e-06 176.40923833438 56.3307146002343 3.1316705208928 0.00208056082777369 -402.309008160703 142.491892391616 -2.82338174760864 0.00538036746172699 LETMD1 other 0.0210009744242114 1 1 3.1316705208928 -2.82338174760864 7.62365902979095e-05 60.8555763543524 18.5347116179551 3.28333008944146 0.00126968397033202 -80.7281703089176 47.5671799414064 -1.69714013755617 0.0916902578836117 SLC4A8 other 0.567886361129128 1 1 3.28333008944146 -1.69714013755617 0.0547729516379608 221.060591133005 95.1507260269058 2.32326751842646 0.0214477747007424 105.062487684729 132.849462760704 0.790838634206402 0.430231181395313 LAMC3 other 1 1 1 2.32326751842646 0.790838634206402 0.964938903321657 2.23958076448831 24.5942880696936 0.0910610121399707 0.927560932671923 -15.7684340320591 74.2180534879141 -0.212460894499569 0.832024843396386 PTGER3 other 1 1 1 0.0910610121399707 -0.212460894499569 0.0797478719301569 -13.2421434327156 13.1052069622709 -1.01044901242986 0.313834950463578 -43.5549707896858 19.7231142471965 -2.20832117300527 0.0286712487976126 TNIP3 other 1 1 1 -1.01044901242986 -2.20832117300527 0.000438961033893442 157.475726479182 44.142855424238 3.56741141835412 0.000486206434469172 2.23796133291832 71.6398504665318 0.0312390564517417 0.975120980499036 MAPK9 other 1 1 1 3.56741141835412 0.0312390564517417 0.138846826762937 120.583399800599 73.8014204742391 1.63388995802174 0.104324658483109 -32.3783603734242 120.619491568311 -0.268433898638074 0.788724595805792 COL23A1 other 1 1 1 1.63388995802174 -0.268433898638074 1.07684184066794e-05 389.045971172773 112.783960915466 3.44947958925092 0.000727066163760407 -81.6472791923303 190.066909337157 -0.429571246657657 0.668115872108447 BCAR1 other 0.0886994624158186 1 1 3.44947958925092 -0.429571246657657 7.66529389311370e-09 150.457420402824 55.595129635474 2.70630577515229 0.00756629232014558 -254.623195359535 89.1133385311434 -2.85729610804054 0.00485981547475289 FAM160A2 other 8.22486034731099e-05 1 1 2.70630577515229 -2.85729610804054 9.66213214576149e-05 230.62212098203 163.715896699768 1.40867274119971 0.161015302150337 -527.852706065972 261.92234009633 -2.01530234447294 0.045671156694275 HERPUD1 other 0.709973470070554 1 1 1.40867274119971 -2.01530234447294 0.00429667907451527 82.9135143959537 34.1196121777854 2.43008372908579 0.0163003506750279 -120.703224530417 114.615640495795 -1.05311303071979 0.294017151393416 HOMER3 other 1 1 1 2.43008372908579 -1.05311303071979 0.000934829467664768 58.4209265999617 21.2254209267408 2.75240367677987 0.00664140122074511 -29.4749512483852 33.2770401111416 -0.885744379606544 0.377163663655747 RAD51 essential 1 1 1 2.75240367677987 -0.885744379606544 2.65896945671392e-07 185.287072780341 34.3518934694959 5.39379504494776 2.55043188776723e-07 -130.020901986631 139.215297662868 -0.933955565009079 0.351788891619024 PIK3CB other 0.00254941991509731 1 0.00289244480391681 5.39379504494776 -0.933955565009079 0.729498486799514 212.195640477911 773.758283000741 0.274240218346985 0.784293036286375 -575.039488470858 1379.67447210161 -0.41679359885156 0.677450027609799 CYBA other 1 1 1 0.274240218346985 -0.41679359885156 0.00496048000560475 200.007615118174 88.816908764073 2.25190921302452 0.0257513819572832 -190.157280321553 143.217919954354 -1.32774781523261 0.186238968904201 THOC3 essential 1 1 1 2.25190921302452 -1.32774781523261 3.9758914541689e-05 301.128306652558 123.101045368952 2.44618805429338 0.0155634291878871 -451.039486708717 247.053686580355 -1.82567397779759 0.0698365334137444 HEBP2 other 0.305984606312839 1 1 2.44618805429338 -1.82567397779759 4.96907531695032e-08 117.920104908792 22.65663220754 5.20466165618158 6.24890707632554e-07 -14.0375401236983 49.7225411834196 -0.282317431683867 0.778086712506884 MPHOSPH9 other 0.000505305268980678 1 0.0069181650242 5.20466165618158 -0.282317431683867 1.42387108042017e-12 142.658965551776 20.517851863465 6.95291917014962 1.1308447849528e-10 -133.992401508941 87.8765761351447 -1.52477949644824 0.129492261028106 PLEKHA5 other 1.80020020697522e-08 1 1.47088981178811e-06 6.95291917014962 -1.52477949644824 0.0910014665093892 217.506071689831 473.06337425447 0.459782100088836 0.646338347693145 -1699.50217020239 980.130109167198 -1.73395568027844 0.0849805241240746 PRSS8 other 1 1 1 0.459782100088836 -1.73395568027844 2.60072778098801e-15 366.833546891208 45.2472711461878 8.10730763643222 1.59459164408979e-13 -251.633229605223 152.880103603627 -1.64595145917505 0.101839939996539 SIKE1 other 3.50604112154993e-11 1 2.18714189903356e-09 8.10730763643222 -1.64595145917505 2.6073040202834e-17 442.270107896026 62.7376448647027 7.04951722127611 5.26470155457159e-11 -186.519985286905 111.618471342739 -1.6710494512523 0.0966914664753052 RRP12 essential 3.60981241608236e-13 1 6.91150020084158e-07 7.04951722127611 -1.6710494512523 0.000237734435822453 63.1732673267326 24.866714695004 2.54047501254458 0.0120472014976199 -35.1762140499765 37.2671650470904 -0.943892941830379 0.346683916951545 FNIP2 other 1 1 1 2.54047501254458 -0.943892941830379 1.12499231250749e-05 141.807345947586 112.320183470094 1.26252772713235 0.208631019762301 -484.645970353133 169.936484438013 -2.8519241877686 0.00493068084595296 MSMO1 other 0.0925081178574906 1 1 1.26252772713235 -2.8519241877686 0.000100402699556958 271.032751909707 118.09304325431 2.29507805405645 0.0230967482583039 -420.923087237205 200.378700354986 -2.1006378746419 0.0373234778543803 TTC17 other 0.73625299585117 1 1 2.29507805405645 -2.1006378746419 0.80882235971759 8.77382251965767 13.5072034922379 0.64956617590752 0.51696594105886 8.94777477178159 23.6449636123294 0.378422014873216 0.705652152810862 ALX4 other 1 1 1 0.64956617590752 0.378422014873216 0.689864672038707 3.74256462623968 19.6130419422434 0.190820202050289 0.848912992275001 -20.0776439207538 32.4301629582997 -0.619104009639749 0.536745153906566 FSTL4 other 1 1 1 0.190820202050289 -0.619104009639749 0.000390110763152186 189.569116258042 65.6457934729945 2.88775725341834 0.00444256969992566 -154.031821410984 114.036371877583 -1.35072537713087 0.178777729540019 FOXN3 other 1 1 1 2.88775725341834 -1.35072537713087 0.00104515933132388 23.6776592170781 13.9077003510345 1.70248557413857 0.0907220573910957 -46.4800993204564 29.1226887842896 -1.5960098899086 0.112577350668374 METTL24 other 1 1 1 1.70248557413857 -1.5960098899086 0.00051443246478428 120.961572980959 91.5260792217661 1.32160772109413 0.188258792470098 -445.972591580024 202.075989317728 -2.20695488407984 0.0287969742754865 AKR7A2 other 1 1 1 1.32160772109413 -2.20695488407984 4.00278423279086e-09 158.752261022051 43.0632579684224 3.68648979458223 0.000314544891029026 -206.850047636801 95.077277768324 -2.17559918091928 0.0311101022143925 MRTO4 essential 4.37064010378434e-05 1 1 3.68648979458223 -2.17559918091928 0.016642708339091 2.56334551668486 1.14818510986347 2.23251938617255 0.0270719556728152 -4.83342431290643 5.24700914057995 -0.921177033126379 0.358447093503515 NNAT other 1 1 1 2.23251938617255 -0.921177033126379 9.31878095242512e-31 194.285853525743 13.4733179968045 14.420045127104 1.94403834924052e-30 -78.2510311090564 130.647675999994 -0.598946980955557 0.550082607805333 USE1 other 1.35140961372069e-26 1 2.82138285625277e-26 14.420045127104 -0.598946980955557 0.891342666379175 2.65725328920689 6.37491698800042 0.416829473106657 0.677407086342035 7.39558491912849 28.7146263756946 0.257554628166378 0.797108407070425 MCF2L2 other 1 1 1 0.416829473106657 0.257554628166378 2.2067234191775e-07 19.6146755828664 3.78568696408501 5.18127245304531 6.95180152059706e-07 -11.1567331547902 17.0827457718298 -0.653099525322689 0.514685287939194 NRIP2 other 0.00213257751229314 1 0.00766922743752268 5.18127245304531 -0.653099525322689 6.3767288396433e-07 1395.60150309518 260.695902192002 5.35336954421066 3.54103834632704e-07 720.198225994318 797.110577335983 0.90351106417542 0.367840657705558 LAMA3 other 0.00591441599876916 1 0.00398012710127159 5.35336954421066 0.90351106417542 1.7466927240308e-07 220.367468458908 50.9511574351088 4.32507286492102 2.71015814675781e-05 -100.053216994852 71.385516616622 -1.40158987056422 0.163024188641466 AP5M1 other 0.00170424809083685 1 0.263833895586873 4.32507286492102 -1.40158987056422 2.69767549287524e-12 115.096733969594 21.8858362023485 5.25895985446712 4.83859935173338e-07 -68.2611577382379 39.7532145929559 -1.71712296570687 0.0879935056273369 ANAPC4 essential 3.38099669522054e-08 1 0.00539939301659928 5.25895985446712 -1.71712296570687 0.54932655214075 -53.5295008300245 85.0145048270049 -0.629651386418719 0.52987424910725 -155.778100733948 142.776726617032 -1.09106087823255 0.276984002159567 KCNQ1 other 1 1 1 -0.629651386418719 -1.09106087823255 9.3466455541882e-07 138.353183692167 59.8532568808161 2.3115397708042 0.0222021013071454 -841.946174988548 219.392836347294 -3.83761926326421 0.000184431465609856 TRAPPC3 essential 0.00854750735930511 1 1 2.3115397708042 -3.83761926326421 1.08120162028352e-06 486.323248019501 119.387719320168 4.07347799915086 7.54586010563012e-05 -816.597562461914 423.303609743553 -1.92910606870711 0.0556443506818907 THRAP3 other 0.00983785354295971 1 0.699425773190856 4.07347799915086 -1.92910606870711 0.0596221376022302 -51.1261287503643 155.386109761738 -0.329026377124435 0.742690812584114 -540.333416151197 241.262528812547 -2.2396076954454 0.0268982458194769 PHPT1 other 1 1 1 -0.329026377124435 -2.2396076954454 0.0416467285983918 59.8846666123028 71.1782807627852 0.841333423209245 0.401820816342104 -189.965397265487 111.360716497679 -1.70585645674654 0.0906004382041653 ENTPD2 other 1 1 1 0.841333423209245 -1.70585645674654 2.37487472015866e-07 208.872926648975 46.1919685951064 4.52184509562347 1.20175194895769e-05 -332.143293217968 145.588123788384 -2.28139002396066 0.0238694586895724 LY75 other 0.0022886667678169 1 0.121148613974424 4.52184509562347 -2.28139002396066 2.00425388611559e-15 409.606188032869 51.4497674365849 7.96128356727239 3.20753637786289e-13 -257.93657491352 167.838655768169 -1.53681268318665 0.126352075727089 ARID4B other 2.70794742553078e-11 1 4.38470222853857e-09 7.96128356727239 -1.53681268318665 1.60445716588681e-06 263.634732001342 59.3950157378276 4.4386676007468 1.71028882632457e-05 -133.245943718787 183.686420805339 -0.725398987767278 0.469301065234638 OPN3 other 0.0143705079570727 1 0.16978037178924 4.4386676007468 -0.725398987767278 2.267545888011e-05 68.4270424872721 24.7270630686591 2.76729356403032 0.00634092053901122 -168.573668297958 75.5984688364042 -2.22985558957224 0.0271940552257567 SDCCAG8 other 0.180564679062316 1 1 2.76729356403032 -2.22985558957224 0.7544213065303 -7.86738186194988 12.2736955348048 -0.640995357888759 0.522588766829367 -19.2135049802013 30.6650005195685 -0.626561377944228 0.53198189188989 PTPRN other 1 1 1 -0.640995357888759 -0.626561377944228 0.00278507624228183 20.4734195402299 8.82242030473059 2.32061257943606 0.0216113947891637 -43.5508261494253 26.9928685446895 -1.61341971036989 0.108687425302253 HHAT other 1 1 1 2.32061257943606 -1.61341971036989 4.67000494050118e-21 1336.40910785166 131.010514523397 10.2007774926568 6.14447089057464e-19 467.708941755003 284.135913897508 1.64607470889341 0.101814528673383 KIF1B other 6.63654402094623e-17 1 8.76754551376096e-15 10.2007774926568 1.64607470889341 0.310843461400066 -181.835431212838 128.488663448002 -1.41518657236579 0.159282882076616 -376.97923734337 318.345434517565 -1.18418295495477 0.238391085156357 FOXC1 other 1 1 1 -1.41518657236579 -1.18418295495477 5.43382979078175e-09 208.507582515611 52.5688495870432 3.96637141869284 0.000111792604693023 -161.654772524532 81.2382762036349 -1.98988432643895 0.0483856063455887 TBC1D22A other 5.88429428043755e-05 1 1 3.96637141869284 -1.98988432643895 0.0595357120630766 449.161625121972 188.148656842915 2.38726989955064 0.0181712120574446 290.229281438407 271.900919791997 1.06740823701675 0.287436589440741 SYNE2 other 1 1 1 2.38726989955064 1.06740823701675 4.53310237945935e-06 366.578243406037 72.5500558785077 5.05276307464062 1.23414131046423e-06 181.182351684221 107.411046039601 1.68681302682241 0.0936905799382746 PLEKHH1 other 0.0387126943205829 1 0.013404008772952 5.05276307464062 1.68681302682241 0.000612926623794653 454.145849263108 118.574080584915 3.83006005210285 0.00018562202610144 104.494670085009 560.645593389584 0.186382754661905 0.852388328677913 ATP9A other 1 1 1 3.83006005210285 0.186382754661905 2.58469536130004e-10 486.248241860267 74.6521994094523 6.51351528430252 9.99410815329106e-10 -302.82743018131 299.171538505669 -1.01222005172652 0.313030925779789 FAM168A other 3.00393294890291e-06 1 1.26125644894533e-05 6.51351528430252 -1.01222005172652 0.00994132776685631 29.7407558144237 13.1247995992749 2.26599694642704 0.0248633282738274 -71.8238975572547 52.5573435011949 -1.36658158066192 0.173774551489559 RELT other 1 1 1 2.26599694642704 -1.36658158066192 0.000269819244533372 66.0776660329918 34.5754422446052 1.91111557056951 0.0578474998521324 -157.076577543386 60.6927504317497 -2.58806161240003 0.010575356902636 GALC other 1 1 1 1.91111557056951 -2.58806161240003 1.46641676242032e-05 198.667740654102 83.800833460982 2.37071318325972 0.0189913374718484 -772.045548837004 248.036083765964 -3.11263400516141 0.00221091466189968 NOP58 essential 0.118955727767537 1 1 2.37071318325972 -3.11263400516141 9.46139608292484e-11 543.725982455309 159.593688071694 3.40693914041921 0.000840821151711438 -1199.00087486995 358.328680692036 -3.34609239917479 0.00103275712808366 SZRD1 other 1.12127004978742e-06 1 1 3.40693914041921 -3.34609239917479 0.378156122342967 87.4781640741906 62.784459985682 1.39330917386468 0.165547174249644 56.635683472142 205.426714772518 0.27569775204193 0.783152231790045 KCNH2 other 1 1 1 1.39330917386468 0.27569775204193 1.089532258429e-08 304.385570391192 53.3612767272741 5.70424077270276 6.61190719964106e-08 -205.833450456781 185.557734638619 -1.10926904156084 0.269202495713292 CUL1 essential 0.000115904441651677 1 0.000775708952661889 5.70424077270276 -1.10926904156084 0.0501420979512014 17.332948899929 16.8098085068054 1.03112113935812 0.304111226241797 -39.5969202314127 25.2219106879749 -1.56994133875398 0.118494552255926 FAM114A2 other 1 1 1 1.03112113935812 -1.56994133875398 1.72720343019064e-07 404.932528651548 91.0357520381595 4.44806045521338 1.65811721225465e-05 -195.700682760302 144.395270393631 -1.35531227738145 0.177315539151995 CYFIP2 other 0.00168557782752305 1 0.16480026972599 4.44806045521338 -1.35531227738145 7.34552261201117e-16 755.788020468246 93.0874072780059 8.11912204419962 1.3641808090372e-13 141.633539534557 191.183649977133 0.740824539920111 0.459920647672907 TAB2 other 9.9943180659024e-12 1 1.87274741464627e-09 8.11912204419962 0.740824539920111 1.87370558533708e-12 233.617033506238 42.2463850408334 5.52987038489648 1.33110488164825e-07 -144.295524323566 86.7659582173605 -1.66304305614982 0.0983245550087395 GINM1 other 2.35843322026378e-08 1 0.00153609503342208 5.52987038489648 -1.66304305614982 0.00477751620344174 505.066843031959 152.568126998324 3.31043483962745 0.00116352646694271 97.154492481038 607.933219769096 0.159811126159447 0.873242029064186 EIF2AK2 other 1 1 1 3.31043483962745 0.159811126159447 1.68129840008178e-06 371.641164021165 71.5925468179063 5.19105941246125 6.38902324069021e-07 436.989550264551 289.619342279278 1.50884104226424 0.133349192612784 USP36 essential 0.0150291263983311 1 0.00706753750885152 5.19105941246125 1.50884104226424 4.61653494600056e-08 663.572693913703 111.622191628118 5.94480975722527 1.78593422601494e-08 126.001144309536 352.430191912527 0.357520857182432 0.721191413798586 KMT2C other 0.000470748068443677 1 0.000214937184100898 5.94480975722527 0.357520857182432 0.303127641168822 17.9869809149323 32.4944732004495 0.553539699012059 0.580691498013144 -127.910923563825 102.816493227333 -1.24407008592489 0.215351832876188 MCOLN3 other 1 1 1 0.553539699012059 -1.24407008592489 0.662418946446654 9.58451841671479 14.2371749851652 0.673203667630806 0.501813824957424 -27.3554627326742 60.5381972878109 -0.451871115398776 0.651989473048229 CCDC85A other 1 1 1 0.673203667630806 -0.451871115398776 2.21289515204262e-15 798.425842348676 92.4053964520714 8.64046768916577 8.04805808072119e-15 -258.514278171785 307.690257378324 -0.840177002594936 0.402155302129542 PUM2 other 2.98674458671193e-11 1 1.12069208774043e-10 8.64046768916577 -0.840177002594936 4.14671599857559e-08 201.748175119501 71.2234043194181 2.83261067127196 0.00523504099778737 -385.059906124351 130.929514350592 -2.94097101050318 0.00377707542558199 MRPL43 essential 0.000424291980974254 1 1 2.83261067127196 -2.94097101050318 0.0209600093916339 11.4280980982495 10.9321859828344 1.04536257580998 0.29752597466828 -43.6035447902325 24.9402561590472 -1.74831984532024 0.0824410045785151 ITIH4 other 1 1 1 1.04536257580998 -1.74831984532024 1.23801217802271e-08 99.0011836907994 25.4791836245222 3.88557126279024 0.00015126866050836 -58.4783140125829 38.9663231979695 -1.50073984952294 0.135470333046139 HPF1 other 0.000131303571601089 1 1 3.88557126279024 -1.50073984952294 1.78911289098973e-05 340.752111932418 71.8134678701337 4.74496110602301 4.74686572789215e-06 -28.8271058403054 288.237257303349 -0.100011726832271 0.920465942606995 ZFR other 0.143916240951214 1 0.0495905062592892 4.74496110602301 -0.100011726832271 0.186103715530546 4.12868453001829 2.67377712044323 1.54413937438955 0.124633994774808 -1.43107334005916 7.12623575948731 -0.200817568820109 0.841109685491772 NPFFR2 other 1 1 1 1.54413937438955 -0.200817568820109 0.360808002567752 12.9509940483728 13.4377361922792 0.963777965503888 0.336658470168721 29.8812207167279 20.9839930042655 1.42400069951672 0.156456296300309 PHF21B other 1 1 1 0.963777965503888 1.42400069951672 0.00407284530712114 59.8882232958701 19.3014715210966 3.10278018079668 0.00227642972386822 9.24192102850435 28.7530731176125 0.321423765407645 0.748319522940511 TRAF1 other 1 1 1 3.10278018079668 0.321423765407645 9.15726449723721e-10 535.426374021769 85.6794352320304 6.24918187861263 3.85699846903313e-09 74.6252092842412 122.71650157246 0.608110631642944 0.544009900304791 RC3H2 other 1.0357781872825e-05 1 4.77187850588778e-05 6.24918187861263 0.608110631642944 0.00844387991519334 19.3722867152081 21.6452655922968 0.894989559384403 0.372265786276628 -103.323155653249 47.6755150292624 -2.1672163497307 0.0318398798677384 IL17RB other 1 1 1 0.894989559384403 -2.1672163497307 4.89324728587621e-10 144.188210663798 43.3009935077382 3.32990536667549 0.00108877313537942 -249.741997029298 91.5393529293765 -2.72824734977071 0.0071125456451828 TRAF3IP2 other 5.61206531217142e-06 1 1 3.32990536667549 -2.72824734977071 0.290590237004742 -12.5158176640689 15.3516209151406 -0.815276623442749 0.416181295640715 -71.1691550037351 45.0955835399217 -1.5781845896446 0.11658851138367 SERPINB3 other 1 1 1 -0.815276623442749 -1.5781845896446 2.5495769866227e-05 369.924351652296 86.616362563767 4.27083683385985 3.60270989085784e-05 -809.17797952461 537.220708671466 -1.50623005863956 0.134293739556889 PKP2 other 0.201850010030919 1 0.345788095324535 4.27083683385985 -1.50623005863956 4.94640533390339e-10 978.295777181281 178.558844765371 5.47884244248319 1.69585773283666e-07 -1315.86003726559 682.701067240037 -1.92743222532994 0.0557545817566396 GDI2 other 5.67055907478684e-06 1 0.00194599674843007 5.47884244248319 -1.92743222532994 0.33891805844134 -24.3990412390141 20.889579786551 -1.16800057676232 0.244611607604459 0.370628725954253 43.2596182952652 0.00856754498906011 0.993175260343057 PRDM1 other 1 1 1 -1.16800057676232 0.00856754498906011 3.20681991276307e-10 122.569000061459 29.3481430882958 4.17638007599669 4.9423720264787e-05 -123.900328805851 60.7762090308721 -2.03863206971192 0.0431972379135828 ATG5 other 3.71221473101453e-06 1 0.467844936026474 4.17638007599669 -2.03863206971192 6.20248407688325e-14 164.728693710458 34.0134891202083 4.84304015763523 3.13638101853945e-06 -207.770827795204 75.0183019883878 -2.76960184765799 0.00631696625217127 PITHD1 other 8.13951985409388e-10 1 0.0331735020330917 4.84304015763523 -2.76960184765799 4.91888961935375e-19 431.456175810073 41.6679603068692 10.3546267355675 2.25454264614576e-19 72.1966634584533 188.20478996604 0.383606939395541 0.701802321199201 MTA3 other 6.91054802623009e-15 1 3.22264325840075e-15 10.3546267355675 0.383606939395541 0.321130127981883 30.5061576991556 20.9980534112962 1.45280884383046 0.148452461089839 -39.9615467017339 100.158407714831 -0.398983446457251 0.690496454705201 USP13 other 1 1 1 1.45280884383046 -0.398983446457251 0.00240227155973272 132.187944744541 37.3838908966899 3.53596005054266 0.000540787070448197 79.0708205255718 159.272310512093 0.496450514664745 0.620303328149129 ATP11B other 1 1 1 3.53596005054266 0.496450514664745 0.000210255096964425 175.147051956435 44.7007263682653 3.91821489685632 0.000134137389877155 -47.544606355267 136.459713558041 -0.348414965234738 0.728007514505221 CDK14 other 1 1 1 3.91821489685632 -0.348414965234738 0.00025989116627973 990.920555801704 238.84628325489 4.14877946727027 5.65162367584549e-05 53.72534829912 949.082470329576 0.0566076710704218 0.954935120006446 SEC61A1 essential 1 1 0.530970044345684 4.14877946727027 0.0566076710704218 1.38824191920199e-14 288.961527357946 47.7047187924046 6.0572944285745 1.0795274178208e-08 -235.521957680943 103.606952008551 -2.2732254266249 0.0244419763557648 PPP1R12A essential 1.84705587349825e-10 1 0.00013120576236194 6.0572944285745 -2.2732254266249 0.696441295494246 5.27756981630378 7.74836424014071 0.681120511728543 0.496831588699644 10.2973196283924 13.8993932475926 0.740846700641117 0.459929341273672 RASGRF1 other 1 1 1 0.681120511728543 0.740846700641117 0.0288481270195687 1.31916390952542 13.7387931560692 0.096017451790711 0.923636603300434 -72.4709282145507 31.7024625274615 -2.28597157560787 0.0236753964837919 CAMK2B other 1 1 1 0.096017451790711 -2.28597157560787 6.53902223436704e-12 304.791455275617 51.6255935094589 5.90388283322637 2.23350730732874e-08 -96.8219415648325 116.2887826863 -0.832599149532923 0.406377107085313 CROCC other 8.08811660168859e-08 1 0.000267797526148715 5.90388283322637 -0.832599149532923 7.82277429102344e-08 2076.68092575531 367.514332047206 5.65061208412565 7.80951209012447e-08 -1141.40853639164 1305.84001749212 -0.874079918751252 0.383472009255499 ATP2B4 other 0.000785171855590023 1 0.000912385297489242 5.65061208412565 -0.874079918751252 1.79159032774961e-11 757.443512705365 109.154712343248 6.93917373281611 1.1061397275462e-10 -637.356329511973 379.643719557357 -1.67882753402346 0.0952676479674282 ZC3H11A other 2.18340890880229e-07 1 1.43941962745587e-06 6.93917373281611 -1.67882753402346 4.52058681452764e-15 87.6234525166964 20.0129093851222 4.37834653775211 2.18232142287929e-05 -87.7428259217028 29.0213454146367 -3.02338932492945 0.00292317890285058 RIOK2 essential 6.06888779850335e-11 1 0.214282140512518 4.37834653775211 -3.02338932492945 6.39655113434557e-06 30.4917716680675 31.1605017460969 0.978539174899094 0.329362591854332 -414.106156321192 95.4640577137231 -4.33782269723973 2.61042453230586e-05 YIPF1 other 0.0537885984887119 0.377389074635458 1 0.978539174899094 -4.33782269723973 1.11410444394681e-10 351.523076220939 64.5553886370796 5.44529408996586 2.03457430097557e-07 -528.539818128572 197.773431146818 -2.67245107223836 0.00835175857961441 NDC1 other 1.31698286318952e-06 1 0.00232165273484322 5.44529408996586 -2.67245107223836 0.364389574319387 18.7821469876984 16.9077118351051 1.11086273357826 0.268393167831059 -53.1642893024452 71.5214014457202 -0.743333998324867 0.458434474025088 DGKG other 1 1 1 1.11086273357826 -0.743333998324867 1.39550627717957e-06 135.615410275741 31.9205996479999 4.24852326620495 3.77536619199186e-05 -48.8905041798154 68.403360352118 -0.71473833928835 0.475889070667818 FLYWCH1 other 0.012566534026002 1 0.361340298235541 4.24852326620495 -0.71473833928835 9.14032108791418e-12 138.07574428079 24.5052071346045 5.63454711981638 9.60412659941976e-08 -99.6445370250889 54.6998561449291 -1.82165994661992 0.0706880132995863 UNKL other 1.12553913876575e-07 1 0.00111715200604451 5.63454711981638 -1.82165994661992 0.0465637987497362 -5.71102676629897 10.6344150928541 -0.537032522845244 0.592015207536509 87.9409322737516 38.5539396927729 2.28098432934563 0.0239115428203331 TBXAS1 other 1 1 1 -0.537032522845244 2.28098432934563 0.0479470710327412 208.390003818149 84.276353618886 2.47269838892803 0.0144968543548212 69.4561415260539 304.340057260308 0.228218861990444 0.819778847260306 PARP12 other 1 1 1 2.47269838892803 0.228218861990444 2.9535714408392e-10 412.353469726921 120.955283034575 3.40913980259175 0.000828294583193467 -704.582719623054 215.396263534202 -3.2711000091753 0.00131703087833908 ALDH18A1 other 3.42525679994122e-06 1 1 3.40913980259175 -3.2711000091753 3.51568879134782e-13 346.166653555695 47.3584108224541 7.30950738303843 1.30763352727315e-11 -167.41915119572 154.335897499268 -1.08477129370705 0.279696532964455 TARBP1 other 4.52363676782724e-09 1 1.73980640803692e-07 7.30950738303843 -1.08477129370705 1.5345246630589e-21 193.491160142348 22.2401381176527 8.70008806234744 5.07822265030177e-15 -10.7528920521944 34.879651333709 -0.308285537298431 0.758287149920521 GATB other 2.18608383499371e-17 1 7.08158148584582e-11 8.70008806234744 -0.308285537298431 3.14163719185262e-11 105.140967423494 24.7568085083021 4.24695159669858 3.74753641867451e-05 -145.425112005467 49.3244207940098 -2.94833897011779 0.00369633038088735 CDK17 other 3.79195609056611e-07 1 0.358826612088084 4.24695159669858 -2.94833897011779 1.34197688012505e-11 54.0557437483645 11.5160703101009 4.69394005878476 5.79983726301144e-06 -56.0842755952604 17.9182453614752 -3.130009354367 0.00208475700832486 DNAJC25 other 1.64190871283299e-07 1 0.0601211130683766 4.69394005878476 -3.130009354367 0.0113190272622117 166.010991048451 65.353205639674 2.54021190580544 0.0120753857483962 -278.348976912865 298.254730790106 -0.93325921830474 0.352156602586422 SLC2A3 other 1 1 1 2.54021190580544 -0.93325921830474 2.1795164681845e-06 97.7828529890343 28.7625120767955 3.3996631701694 0.000864560093417151 -67.0076830943466 50.800496041712 -1.31903599995022 0.189167161516745 PSD other 0.0192712846116874 1 1 3.3996631701694 -1.31903599995022 5.04754743083012e-15 175.701618962216 31.3608629078302 5.60257603493261 1.46467884221114e-07 -79.1669373015681 57.4024362530473 -1.37915639943532 0.17052286097359 CTDP1 other 6.76977061422936e-11 1 0.00168716355834301 5.60257603493261 -1.37915639943532 6.19140226328881e-09 902.732979463883 176.157457203217 5.12457998540749 8.70727107242421e-07 -1601.22679099917 727.448592722151 -2.20115456544812 0.0291940361978529 YBX3 other 6.68485702367293e-05 1 0.00954578127669866 5.12457998540749 -2.20115456544812 0.139093840405381 -4.9087420631758 4.10333417204137 -1.19628133058774 0.233401816091015 -32.2100985627374 16.944866917991 -1.90087645530806 0.0591623952298493 STYK1 other 1 1 1 -1.19628133058774 -1.90087645530806 2.97157829001316e-10 1830.02141605142 280.316268570879 6.52841672508456 1.17499972390252e-09 -500.966962341315 1141.68455825853 -0.438796302111212 0.661495358628739 WNK1 essential 3.44554502727026e-06 1 1.47873715253132e-05 6.52841672508456 -0.438796302111212 1.23170932070161e-05 260.839357355127 63.0179318272857 4.13912913026111 5.73941540187168e-05 -117.519498514115 135.346680412432 -0.868285045159633 0.386598214127205 CCAR1 essential 0.10080309080622 1 0.538816317927713 4.13912913026111 -0.868285045159633 0.0898418733727766 92.9603155191388 70.7048865817174 1.31476507513663 0.19113841742061 -250.816008316008 247.406972527764 -1.01377906108876 0.312762395852806 OGFR other 1 1 1 1.31476507513663 -1.01377906108876 0.688356490045937 -14.5350435567558 16.9408776754017 -0.8579864535508 0.392277969708846 -8.18478779383379 25.3520315228882 -0.322845440865141 0.747264899174408 GNA15 other 1 1 1 -0.8579864535508 -0.322845440865141 2.271055951335e-08 82.5329814840791 23.8094517268553 3.46639571674756 0.000684858476342718 -109.068666713424 50.2050088781082 -2.17246583858256 0.0313599230498962 PIGV other 0.000236689451248134 1 1 3.46639571674756 -2.17246583858256 0.000950486840299271 87.4612274368235 169.800471817879 0.515082358137562 0.607238836851991 -1147.18767749699 408.820750372825 -2.8060896528633 0.00566696319291563 PTPRU other 1 1 1 0.515082358137562 -2.8060896528633 2.36091818520156e-14 195.694300569301 39.7704795793763 4.92059192242634 2.19598915644356e-06 -380.204525442447 102.01868491548 -3.72681264963804 0.000271810956806394 SNRNP40 essential 3.12798050357355e-10 1 0.0234883000173203 4.92059192242634 -3.72681264963804 0.17293189384484 18.2414409810935 43.3050302014618 0.421231457321041 0.674193087871907 -110.193663771078 83.7264181038166 -1.31611582421266 0.190156326075389 RIMBP2 other 1 1 1 0.421231457321041 -1.31611582421266 0.831105930318744 114.603600579584 221.870215140476 0.516534409573737 0.606273557828198 323.822857750253 688.934386633279 0.47003439519506 0.639041504831908 COL11A1 other 1 1 1 0.516534409573737 0.47003439519506 4.37145702613395e-05 286.641202786115 83.3359507981813 3.43958639747554 0.000749778549398174 -127.253666685542 135.168296229453 -0.941446110036962 0.347950748057906 QSER1 other 0.335203324763951 1 1 3.43958639747554 -0.941446110036962 0.0242547795163155 27.9510869764693 42.3082986808564 0.660652587032921 0.509815817181703 -164.321543532279 88.5890206585602 -1.85487481756467 0.0655137666861352 MPC1 other 1 1 1 0.660652587032921 -1.85487481756467 0.000102355536647607 74.890579645194 38.5632591610223 1.94201893912767 0.0539597575238128 -226.25034301592 83.6550280073069 -2.70456359175635 0.00760933547880625 ACAA1 other 0.749959017017018 1 1 1.94201893912767 -2.70456359175635 2.45893933610265e-69 6514.13166583744 192.720612335776 33.8009078888143 2.35487894465529e-70 3756.21538739879 3402.04114321909 1.10410639650424 0.271388541161634 BCAT1 other 3.59349394578041e-65 1 3.44142008971923e-66 33.8009078888143 1.10410639650424 1.10127782873884e-08 1206.36472739587 212.702898939766 5.67159513767365 7.41282919880651e-08 -716.91434981375 709.098998439799 -1.01102152363936 0.31369024847163 HDAC7 other 0.000117098871529801 1 0.000866782118216446 5.67159513767365 -1.01102152363936 0.189341067611222 43.3743404147928 24.3999837598629 1.77763808540488 0.0774895919180797 70.7879118105898 45.0862097494262 1.57005683564897 0.118508949057624 LZTS1 other 1 1 1 1.77763808540488 1.57005683564897 0.214945946935053 3.79128832582674 5.45239185970698 0.695344066123393 0.487880858027743 13.7226450540716 7.9595463754917 1.72404863376701 0.0866928129812614 PRDM6 other 1 1 1 0.695344066123393 1.72404863376701 2.41552050956318e-08 1002.24734082737 182.640897341993 5.48752965744944 1.6147045039384e-07 -739.730819206479 613.326715008364 -1.20609587207756 0.229606534673524 NCKAP1 other 0.000251262443404762 1 0.00185464959322365 5.48752965744944 -1.20609587207756 7.77637403251109e-23 221.274726973189 19.2061053129542 11.5210618377659 2.99051713961667e-22 -584.836933619637 245.503062061841 -2.38219812293958 0.0184977584419265 MRPS35 essential 1.11295465153299e-18 1 4.30365321562235e-18 11.5210618377659 -2.38219812293958 5.07531519546288e-06 202.516026396411 134.216426523104 1.5088766080473 0.133340107392683 -581.55585670517 209.958660548374 -2.76985886262683 0.00628460907898881 GUCY1B3 other 0.0431503297918254 1 1 1.5088766080473 -2.76985886262683 1.18712146703622e-10 255.065389332586 48.0160772871457 5.31208303017434 3.90287714273733e-07 -128.240533467247 92.8158501202809 -1.38166631346973 0.169156306383922 SFSWAP essential 1.40127817968955e-06 1 0.0043759058524371 5.31208303017434 -1.38166631346973 5.10869984064167e-05 303.37201998517 67.4742765677172 4.49611371054428 1.38814931784441e-05 23.2180588607521 251.063684026391 0.0924787627122987 0.926442726999343 TNK2 other 0.388618796877612 1 0.138870457757155 4.49611371054428 0.0924787627122987 9.55631822000639e-09 157.953215478131 27.5119744234875 5.7412533556037 5.20003701627575e-08 -76.9194748988852 67.8947589271242 -1.13292212999015 0.259091403541461 MON2 other 0.000102013696998568 1 0.000613292365699562 5.7412533556037 -1.13292212999015 6.19618336157723e-13 2525.45218637993 334.010065690748 7.56100622643566 3.5246445082397e-12 1608.29096774194 538.301520811802 2.98771395874287 0.00327815293537857 CDH3 other 7.91686348108723e-09 1 4.7406468635824e-08 7.56100622643566 2.98771395874287 1.88818330003662e-15 354.829279596011 93.1898476079579 3.80759587770493 0.000202169991340119 -471.14917060854 130.864649705426 -3.60027839198047 0.000428131777980437 GPBP1 other 2.5524461849895e-11 1 1 3.80759587770493 -3.60027839198047 4.8966289837628e-05 94.2321183617482 20.5876187702398 4.57712567020934 9.6920107002687e-06 57.7393614615837 74.088289917124 0.779331815138015 0.436988068363459 DGAT2 other 0.3732210611424 1 0.0985483648003321 4.57712567020934 0.779331815138015 3.44495293065832e-13 13.3814637565346 2.35036736564299 5.69334987889175 6.07097200627757e-08 -39.5311965678417 10.1260679690396 -3.90390393277116 0.000140867649635527 ZNF112 other 4.43365442175725e-09 1 0.000713885598218179 5.69334987889175 -3.90390393277116 1.90270729131274e-08 692.68118572293 155.223453450875 4.46247761097616 1.70981456243843e-05 -1091.63448275862 419.802272206783 -2.60035391666701 0.0103658478778731 CS other 0.000199536913639967 1 0.169750389758887 4.46247761097616 -2.60035391666701 0.797543662728732 9.56750971220172 15.5657399893773 0.614651774906364 0.539715954521777 2.21179206638654 22.9340325060565 0.0964414812703542 0.923298680302562 LTK other 1 1 1 0.614651774906364 0.0964414812703542 0.00709951390991242 -14.8464512453201 85.5272226890979 -0.173587435421454 0.862420667216406 -562.670879746983 196.846594010395 -2.85842324362122 0.00485539491786098 MRPS24 essential 1 1 1 -0.173587435421454 -2.85842324362122 3.95154831407891e-08 267.673526121935 44.1556304869544 6.06204742566224 1.00609882742012e-08 156.822811705847 191.588928648507 0.818537964652212 0.414323122615747 ELMO2 other 0.000404954671226806 1 0.000122421120089697 6.06204742566224 0.818537964652212 8.55376628667568e-13 356.361674891782 58.3951423271097 6.10259108361386 8.2073569716056e-09 -121.372875646358 109.705942632507 -1.10634732024439 0.270312719437031 WAPL other 1.08812460932801e-08 1 0.000100236450694219 6.10259108361386 -1.10634732024439 6.72822679149534e-15 320.25620887285 35.9629920398841 8.90516029694292 1.24763908291674e-15 189.134950116749 145.249979319332 1.30213409325819 0.194777643728066 APPBP2 other 9.00573156041651e-11 1 1.74844141079952e-11 8.90516029694292 1.30213409325819 1.03673415091056e-07 261.843817787419 64.4400992981994 4.06336769556677 7.6432912952026e-05 -135.518438177874 115.867895923055 -1.16959436518868 0.243948136013943 POLD1 other 0.00103041007259 1 0.707768773935761 4.06336769556677 -1.16959436518868 0.748373660907137 -25.5361151079137 34.4711610747415 -0.740796489347876 0.460103402716516 9.07386091127063 149.515581824665 0.0606883964904169 0.9516971244202 SEZ6 other 1 1 1 -0.740796489347876 0.0606883964904169 3.38839595822361e-08 1036.76485868125 304.885906541018 3.40050109381416 0.000870629768392539 -2758.48812165626 759.630016859354 -3.63135745090889 0.000391138443761132 EIF4B essential 0.000348878546810315 1 1 3.40050109381416 -3.63135745090889 0.00582532897890949 7.05775909831391 4.55888352326607 1.54813323531846 0.123603629916361 -11.133462610292 7.99507794045453 -1.39253959663825 0.165728093847087 SLC6A16 other 1 1 1 1.54813323531846 -1.39253959663825 1.9106222594199e-11 122.007692202686 44.4553854241426 2.74449745601412 0.00677140568029345 -358.398110734958 85.5588705250786 -4.18890652173705 4.6747907510602e-05 BICRA other 2.32560941416591e-07 0.672982876522626 1 2.74449745601412 -4.18890652173705 9.6303339022272e-12 208.796408303148 41.5970372024779 5.01950192478397 1.39065464061155e-06 -119.761592002239 72.5512389434706 -1.65071739292493 0.100795302327017 SPHK2 other 1.18501258666906e-07 1 0.0150621804124637 5.01950192478397 -1.65071739292493 0.000818115473891493 2798.54580389031 1719.1798178425 1.62783774846914 0.105564454394496 -5393.47498579098 2998.49782915917 -1.79872565967587 0.0739830308377677 RPL18 essential 1 1 1 1.62783774846914 -1.79872565967587 0.644996292758138 11.2465665108627 39.8474547720767 0.282240523897748 0.778130809644191 -37.6060861192874 69.4997145682735 -0.541096986554452 0.5892076680698 CA11 other 1 1 1 0.282240523897748 -0.541096986554452 1.40508858843675e-13 467.877498769248 83.7122433173998 5.58911671970447 1.04779112195871e-07 -371.047649304391 165.583798536194 -2.24084513451529 0.0265048685419441 ISOC2 other 1.82633414725009e-09 1 0.00121606637614528 5.58911671970447 -2.24084513451529 4.48283250133038e-09 617.320534613311 148.923429004842 4.14522106251824 5.63879032390669e-05 -571.044094875571 307.995633060848 -1.85406555671117 0.0656805605581985 U2AF2 essential 4.88045974419838e-05 1 0.529877126737511 4.14522106251824 -1.85406555671117 2.01262672004157e-15 1023.9345721398 186.929599556193 5.47764813368679 1.73295274510071e-07 -1219.31680199145 402.132097456922 -3.03213001325284 0.00285297865739308 EPN1 other 2.71885743610416e-11 1 0.00198700361753247 5.47764813368679 -3.03213001325284 1.03427021793067e-24 376.686745522882 39.5334005390956 9.52831631952245 3.31434241634469e-17 -432.44419632987 145.883183027287 -2.96431834949052 0.00351639030676218 MED29 other 1.48831484360224e-20 1 4.69078882185264e-13 9.52831631952245 -2.96431834949052 0.122034260035603 25.6942179446111 14.5782234866408 1.76250679433998 0.0805297270630032 -22.0320408282127 49.8114788672834 -0.442308506577659 0.659062143517625 AHRR other 1 1 1 1.76250679433998 -0.442308506577659 0.0201567736053037 537.234114743986 208.154815700026 2.58093531459872 0.0108671415215053 51.4984246937516 457.189400498683 0.112641335598724 0.910473994455476 GPC1 other 1 1 1 2.58093531459872 0.112641335598724 4.10058693846209e-07 72.3225545010336 14.5436724158643 4.97278489455964 1.7328674413478e-06 -11.1688921255403 23.0875259403995 -0.483763056915359 0.629236779878912 ADCK1 other 0.00387054401121437 1 0.0186508522712264 4.97278489455964 -0.483763056915359 1.42280598016877e-06 75.7926002157445 30.0809841922716 2.5196183652534 0.012896483097782 -176.332585254161 64.6779265567582 -2.7263178435292 0.00724203669952263 HAGH other 0.0128038310155388 1 1 2.5196183652534 -2.7263178435292 2.97014496090489e-09 525.100525215395 117.680726881474 4.46207751371443 1.5712367455292e-05 -342.756903757412 222.906847223097 -1.53766879764964 0.126208696467455 RNF4 essential 3.27012960195628e-05 1 0.156400905649977 4.46207751371443 -1.53766879764964 0.00138404227247504 92.8852956822411 50.6808979161613 1.83274763276484 0.0687588979813955 -346.374013653693 149.100690547248 -2.32308792388813 0.0214743978245867 CASP8 other 1 1 1 1.83274763276484 -2.32308792388813 0.0982822852526957 -48.9760290886566 65.242280202907 -0.750679297785708 0.453991156970811 -228.470843266707 110.51556000557 -2.06731833286817 0.0403776847053664 LIMCH1 other 1 1 1 -0.750679297785708 -2.06731833286817 1.52373936348905e-55 254.120667514841 9.99447765707611 25.4261079201996 4.61538562757718e-56 -76.2512312185181 123.776165068663 -0.616041312769859 0.538807216671039 INTS13 other 2.22404997494862e-51 1 6.73800147769993e-52 25.4261079201996 -0.616041312769859 5.85656474779394e-39 440.614084899861 24.5803399375594 17.9254675085511 5.06900730118545e-39 -475.940532422684 304.298534335538 -1.56405791918105 0.119925373205801 TM7SF3 other 8.52657261631319e-35 1 7.38250223344649e-35 17.9254675085511 -1.56405791918105 0.117895377270633 29.1788505482267 14.226708165867 2.05099100986926 0.0419194618854968 -11.0363500201626 58.4888345560667 -0.188691570005267 0.850576708120411 DLX3 other 1 1 1 2.05099100986926 -0.188691570005267 0.019688776355803 24.547555843315 37.0722529888323 0.662154411028372 0.508895105031719 -238.180657170605 98.4027276968691 -2.42046803727153 0.0167038241603397 SPA17 other 1 1 1 0.662154411028372 -2.42046803727153 0.00431801957563666 29.4229556970321 9.82549440224184 2.99455218154913 0.00321927480080184 11.2069694672585 16.7146969462521 0.670485950376226 0.503585971829587 TSPAN32 other 1 1 1 2.99455218154913 0.670485950376226 0.512660344966123 1.62455828771263 3.84434342520748 0.422584069118369 0.673184395330791 -14.6566636761448 16.8582935519098 -0.869403752581138 0.385970626860539 WISP2 other 1 1 1 0.422584069118369 -0.869403752581138 0.677340759331755 0.444758143773565 14.1168731254011 0.031505428987195 0.974910087809797 -25.9654974417621 35.0898559687582 -0.739971616437529 0.460521920656129 DMRT3 other 1 1 1 0.031505428987195 -0.739971616437529 0.137651416079348 37.0989487896615 20.4406879162802 1.81495598101244 0.0714639370937702 19.0366476998746 37.6589245741158 0.505501628502665 0.613924634452222 ATP2C2 other 1 1 1 1.81495598101244 0.505501628502665 0.41512292656048 105.208385566334 86.5313363681634 1.21584145099419 0.225881985585367 202.218375730458 356.343242880177 0.567481998805449 0.571202508487476 NGFR other 1 1 1 1.21584145099419 0.567481998805449 4.54632858152811e-05 240.5651760659 59.6408094224698 4.03356658629229 8.64643103278338e-05 -151.565515524577 165.806069559252 -0.914113192161604 0.362095680571001 CDON other 0.347657746629454 1 0.796163369498693 4.03356658629229 -0.914113192161604 1.00021457006585e-09 197.516356604991 29.1859680046328 6.76751090022571 2.75909091100693e-10 67.7309410243631 158.029394895374 0.428597104160308 0.668831297031207 TAF2 essential 1.12924224960435e-05 1 3.5437763660973e-06 6.76751090022571 0.428597104160308 8.15438485832669e-05 542.498680523438 122.578685112235 4.42571789725693 1.80390838407318e-05 731.478616317979 440.013213213692 1.66240147875454 0.0984532630404501 HIPK2 ts 0.60505535648784 1 0.178659086358607 4.42571789725693 1.66240147875454 1.86532832087776e-09 319.315698019628 49.7307702925771 6.42088783545929 1.55212611581454e-09 -137.694308616535 179.763355866403 -0.765975401120497 0.444848378578189 TNPO3 essential 2.07573735547277e-05 1 1.94683178706618e-05 6.42088783545929 -0.765975401120497 8.5062074283943e-09 668.578673059079 118.54308722217 5.63996339833844 8.37381370098048e-08 -191.402731209402 399.577187398781 -0.479013160024025 0.632636242211268 RFXANK other 9.10759629358178e-05 1 0.000976554153808343 5.63996339833844 -0.479013160024025 3.05736302518488e-08 210.873878750387 41.1675099627497 5.12233746809549 9.26555472586467e-07 -139.994324157129 138.764716092618 -1.0088611002792 0.314687807616262 TMEM161A other 0.00031585617413185 1 0.0101439293138766 5.12233746809549 -1.0088611002792 9.96824971248251e-15 192.588258334921 25.7358010148187 7.48328207169569 5.43591030666834e-12 -88.0380415317202 84.0368120865391 -1.04761281807145 0.296479996872131 LPAR2 other 1.32986419414229e-10 1 7.28901213021158e-08 7.48328207169569 -1.04761281807145 0.0454856746377054 574.513000777046 229.125331438761 2.50741808934644 0.013191844291455 690.853376710239 1028.16630917171 0.671927654648391 0.502630047009334 CTSA other 1 1 1 2.50741808934644 0.671927654648391 7.95862559913187e-06 276.974621094959 86.1097931562449 3.21652870066001 0.0015937869607082 -614.296012991028 290.253187791353 -2.11641435419001 0.0359827947306879 SUGP2 other 0.066390854747958 1 1 3.21652870066001 -2.11641435419001 0.00516611732532119 141.805628546182 57.6691335686162 2.45895195178298 0.0150342572320088 -40.4372325830155 85.2834151096884 -0.474151187906894 0.636059354144355 SLC12A2 other 1 1 1 2.45895195178298 -0.474151187906894 1.87105810650138e-05 60.7121799657989 24.6218116252053 2.46578850045494 0.0147612176137006 -71.0952214648711 35.9435742188153 -1.9779674951651 0.0497051621958745 SNX24 other 0.1501711236278 1 1 2.46578850045494 -1.9779674951651 0.0958780248321167 511.279664441054 240.161627369135 2.12889823425124 0.0348742334249299 201.132678107859 1069.57528256315 0.188049108264602 0.851088969137084 EYA2 other 1 1 1 2.12889823425124 0.188049108264602 0.547895920331253 -363.340163553141 348.241005667259 -1.04335835711521 0.298593542433157 -406.347606244418 520.782323834823 -0.78026382165248 0.436562275091949 CNN2 other 1 1 1 -1.04335835711521 -0.78026382165248 0.840615333716599 -20.8389401607622 35.832912601161 -0.581558646731024 0.561805928329015 -18.7270020839537 53.5868757283376 -0.349469936984039 0.727265425162123 ABCA7 other 1 1 1 -0.581558646731024 -0.349469936984039 0.605279397731538 11.12208868229 43.6661217446714 0.254707499496386 0.799286645730372 59.9334039837182 63.744963679712 0.940206104514466 0.348574776614649 SNCAIP other 1 1 1 0.254707499496386 0.940206104514466 7.8393808721377e-13 106.985443508424 18.3379071964795 5.834114131026 3.11552482228384e-08 -219.846520736449 59.268441387774 -3.70933528179128 0.000290205963751507 DDX20 essential 9.98266760258014e-09 1 0.000371121316830451 5.834114131026 -3.70933528179128 5.50739442535766e-07 311.0163257014 66.3352622489498 4.68855198814449 6.10356857197572e-06 -132.506454299819 111.503065136102 -1.18836602507815 0.236554910761812 BTBD1 other 0.00513674678053109 1 0.0631597275828048 4.68855198814449 -1.18836602507815 0.0520109502385288 16.1596599162608 8.30476376096552 1.94583017426881 0.0535959028128952 -69.6179184824404 61.7706572299225 -1.12703865564047 0.261575051180249 FAR2 other 1 1 1 1.94583017426881 -1.12703865564047 0.931500573702226 -1.52982759864387 5.94817671873233 -0.257192694666595 0.797373342624045 4.95873908966311 26.3252435929506 0.188364414260955 0.850838982001982 BCAS1 other 1 1 1 -0.257192694666595 0.188364414260955 0.616888543681286 -73.6749457315026 84.7118287998577 -0.86971261009568 0.385802301958447 -193.08225420113 274.18894441839 -0.704194162936426 0.482368497585779 CHI3L2 other 1 1 1 -0.86971261009568 -0.704194162936426 0.923961883322134 7.65702210663145 193.816928749408 0.0395064670358669 0.968543283776931 -97.2515250898807 290.804555928336 -0.334422288465958 0.73856498818417 SBNO2 other 1 1 1 0.0395064670358669 -0.334422288465958 1.51421986335629e-08 92.1156367111094 16.8249136600538 5.47495449737806 1.76944066613768e-07 -86.0404706093136 60.6786415510867 -1.41796962505949 0.158246474035852 PMS1 other 0.000159674484590921 1 0.0020267173389941 5.47495449737806 -1.41796962505949 6.42694681539795e-06 186.827130684947 128.561184642287 1.45321569029393 0.148266751557242 -681.240351096073 192.391874147325 -3.54089981250668 0.000532508715235785 HMG20B other 0.0540249149302352 1 1 1.45321569029393 -3.54089981250668 0.639396688691624 -7.10613510855585 12.9516470855869 -0.548666517980084 0.58401871522025 23.3933731749755 42.7107478391048 0.547716309325709 0.58466952215597 CALCRL other 1 1 1 -0.548666517980084 0.547716309325709 1.67087496678828e-14 157.994282083863 24.3591724887389 6.48602829824794 1.13689988250875e-09 -170.342439644219 69.8288692227209 -2.43942715298607 0.015846358777679 TAF11 other 2.21959030588155e-10 1 1.43147064206677e-05 6.48602829824794 -2.43942715298607 4.75215042033804e-15 554.663597989535 70.2027224678131 7.9008844456686 4.78424040025021e-13 -84.6764265736431 206.437295644071 -0.410179886872951 0.682240387464895 ANKS1A other 6.37738586409365e-11 1 6.52857445018143e-09 7.9008844456686 -0.410179886872951 0.0113656165127662 532.298058415711 230.094215965088 2.31339173904518 0.0221576966960124 -250.381262496964 345.848009870475 -0.723963288355296 0.470296285296211 AP3D1 other 1 1 1 2.31339173904518 -0.723963288355296 2.23425714411864e-11 153.150368127542 30.255199117092 5.06195208085815 1.17699812023041e-06 -251.345558252362 89.5108888863052 -2.80798862998238 0.00563530816152865 ZNF76 other 2.71350530153209e-07 1 0.0128104475405878 5.06195208085815 -2.80798862998238 0.000243150315182082 164.023218957055 269.173871853203 0.609357876482555 0.543289178961358 -1802.6258361816 567.968834435012 -3.17381117922565 0.00185530548198749 SLC9A3R2 other 1 1 1 0.609357876482555 -3.17381117922565 3.68935210416434e-07 183.55015180157 47.1610067777683 3.8919896826311 0.000154140081726335 -145.259532947623 99.5118206159281 -1.45972138835909 0.146639344426957 NTHL1 other 0.00349270963701238 1 1 3.8919896826311 -1.45972138835909 7.93906726018325e-10 170.829088812961 34.241234995155 4.98898736675627 1.62153929328794e-06 -207.569550960568 98.5562014275697 -2.10610340043507 0.0368171404517261 UHRF1BP1 other 9.00845962012994e-06 1 0.0174883012781105 4.98898736675627 -2.10610340043507 2.16949507926389e-12 1417.9147034931 197.785870084595 7.16893832146169 2.95273738406965e-11 -67.5590826719991 377.504829440464 -0.178962167906924 0.858202638190361 IPO5 other 2.72597056709507e-08 1 3.90027081061761e-07 7.16893832146169 -0.178962167906924 0.410248041090701 106.505689714482 105.23549787467 1.01206999411287 0.31308184556683 -58.8187684898521 191.340611293896 -0.307403473272632 0.758948925795323 OAT other 1 1 1 1.01206999411287 -0.307403473272632 5.4457171246423e-11 285.016100869 43.223095186371 6.59406966669224 7.322063932613e-10 -333.001380654593 157.484949226162 -2.11449654262753 0.0361718975968275 WDR3 essential 6.51688968305944e-07 1 9.27925162180046e-06 6.59406966669224 -2.11449654262753 8.0824335834886e-11 239.714377191645 42.90058421877 5.58767162631704 1.0100720832297e-07 -461.520963561519 140.830639212767 -3.27713462170865 0.00129430227534185 PKN2 other 9.6059723139762e-07 1 0.00117369813153247 5.58767162631704 -3.27713462170865 8.84933026437548e-05 273.758261387318 88.43603598288 3.09555101995202 0.00237628824586692 -195.50401905329 132.253018973619 -1.47825751404803 0.141601311755853 WDR18 essential 0.653346053418842 1 1 3.09555101995202 -1.47825751404803 1.70403309829902e-08 294.227234036711 53.9368481980182 5.45503202108725 1.97549900142063e-07 -97.1203613448845 161.13621309304 -0.602722128568378 0.547603696469977 TRAM2 other 0.00017928132227204 1 0.00225601985962236 5.45503202108725 -0.602722128568378 0.825873979350071 94.7715413433237 176.399402160163 0.537255456553505 0.591892588457829 382.735242172872 846.557115791078 0.452107997243895 0.651848669169821 NTN1 other 1 1 1 0.537255456553505 0.452107997243895 3.50980839893248e-14 92.8230352343325 11.5050959851722 8.06799311835058 1.83253335630635e-13 -36.563435996103 57.4193065920784 -0.636779476559324 0.525207819698847 MCM10 other 4.63189414407119e-10 1 2.51221997816037e-09 8.06799311835058 -0.636779476559324 0.932703478606156 11.698051370646 41.7138383103548 0.280435746133247 0.779566243736126 -15.6042580219002 114.559452184647 -0.136211004193258 0.891854426233176 DGKA other 1 1 1 0.280435746133247 -0.136211004193258 0.0589515968599248 277.597060800801 239.192173304016 1.16056080333353 0.24796380345291 -1011.18709976984 652.11775973216 -1.55062039743428 0.123442593780141 ERBB3 other 1 1 1 1.16056080333353 -1.55062039743428 0.0293663497345319 13.917530745739 5.95044895475756 2.33890431655774 0.0206337915401751 -10.5857321200116 20.6507258419503 -0.512608234743376 0.608964642183735 ANKRD44 other 1 1 1 2.33890431655774 -0.512608234743376 8.73075349679436e-17 1255.02763737626 153.797834054481 8.16024260089174 1.10764261082926e-13 341.025166006818 271.547811807027 1.25585680008781 0.21106988809145 KARS essential 1.20222475650858e-12 1 1.52234400432374e-09 8.16024260089174 1.25585680008781 4.72275946383127e-18 154.180987621354 18.8171724686541 8.19363206019348 9.13135736830996e-14 22.433067304627 33.2238879674232 0.675208973935355 0.500555539695615 ADAT1 other 6.5863603482591e-14 1 1.25583557886367e-09 8.19363206019348 0.675208973935355 2.77024194643568e-14 100.674903004266 16.5894561493462 6.06860780112034 9.96376101927949e-09 -152.022253274071 49.1760404472515 -3.09138864966439 0.00237306205150635 TBC1D22B other 3.66336794996654e-10 1 0.000121288862887689 6.06860780112034 -3.09138864966439 6.37101048935503e-13 1028.26769527808 164.484548838286 6.25145463534711 3.86081580339226e-09 -263.682554204155 381.974671364228 -0.690314238015857 0.491042438326732 SPEN other 8.13578039490637e-09 1 4.77621523037657e-05 6.25145463534711 -0.690314238015857 0.0318312060361747 354.348197644958 133.450622697959 2.65527571532551 0.00876884668494302 210.240878002136 579.373766690205 0.362876074288247 0.717201569440663 MYLK other 1 1 1 2.65527571532551 0.362876074288247 2.10310170426668e-08 259.667624291757 54.9298588659857 4.72725817346949 5.00303002024134e-06 -438.577185722267 183.792182654976 -2.38626681171519 0.0182037142303356 ZC3H15 other 0.000219816190129953 1 0.0521465819009755 4.72725817346949 -2.38626681171519 3.85027544792566e-09 189.841118242982 29.0617868892486 6.53232779410453 9.05980694662708e-10 5.37224499264731 111.306545795904 0.0482653104921435 0.961567746807009 MAP2K4 other 4.20758100949316e-05 1 1.1450156295316e-05 6.53232779410453 0.0482653104921435 2.50626411197778e-07 55.0999919293302 11.7828707414899 4.67627907818014 6.28351805641761e-06 -51.3296208252628 35.2229393561584 -1.45727817619765 0.147049630936847 TMEM206 other 0.00240952231725544 1 0.0649275920769632 4.67627907818014 -1.45727817619765 2.94815738083244e-05 100.765240409694 55.7084903072515 1.80879503023576 0.0724209349506704 -236.955896045902 95.2733693634381 -2.48711573474419 0.0139375822927507 SLK other 0.23137139124773 1 1 1.80879503023576 -2.48711573474419 0.0979855573423884 25.7608468928941 16.6714251059425 1.5452096463974 0.12437502757194 -13.5209229267974 31.6646774739938 -0.42700333638017 0.669981118976263 CYB5R4 other 1 1 1 1.5452096463974 -0.42700333638017 3.7290230406788e-12 185.779324968407 47.9000398576699 3.87847954866908 0.000154971176662657 -283.309055798257 82.2493797355118 -3.44451297638098 0.00073606451082537 GSTO2 other 4.6508375363346e-08 1 1 3.87847954866908 -3.44451297638098 2.03330627113636e-17 102.689967131506 11.5749401570425 8.87174929099105 1.77407984900724e-15 -77.2171873504163 58.7097335421152 -1.31523654923463 0.190398112744376 SEC61A2 other 2.818162491795e-13 1 2.48300215667053e-11 8.87174929099105 -1.31523654923463 4.58579443714096e-06 69.0471408168063 16.6419672682186 4.14897708329631 5.50522643404317e-05 -79.3583093787474 64.4961751579492 -1.23043435032234 0.220410635539571 PRKCQ other 0.0391443413154353 1 0.518041807443463 4.14897708329631 -1.23043435032234 0.0627524273590767 51.156180509178 96.9938239871807 0.527416884975471 0.598688574078446 -255.398645227104 145.151303867742 -1.75953393749613 0.0805392358448597 TLE2 other 1 1 1 0.527416884975471 -1.75953393749613 2.13780458907708e-09 148.232374029078 24.5441027882288 6.03942932068264 1.22331530090843e-08 4.29031069508067 54.8148662062945 0.0782691082184564 0.937721157614568 ASB1 other 2.37253553295774e-05 1 0.000148351446541166 6.03942932068264 0.0782691082184564 1.08847670322332e-06 174.457809649086 34.1755977078626 5.10474787128446 9.52668992485494e-07 -51.6060168880215 170.622967769255 -0.302456448640677 0.762707024886812 FAM107B other 0.00990078409251933 1 0.0104221987777913 5.10474787128446 -0.302456448640677 0.130538445705706 1.60935768401323 15.3933577631931 0.104548839101327 0.916871641596374 -47.8933983636022 29.237195123743 -1.63809825672056 0.103469634569123 ME1 other 1 1 1 0.104548839101327 -1.63809825672056 5.11778503095597e-06 330.276519293862 92.4357088612246 3.57304036895213 0.000471410482060079 -141.318543977502 161.34560691885 -0.875874755292096 0.382462237934526 TBC1D1 other 0.0435011727631258 1 1 3.57304036895213 -0.875874755292096 2.91242024380057e-12 326.153720064027 57.3385424627926 5.68821086227768 6.33823650800327e-08 -231.627926901844 129.135070264455 -1.79368723327826 0.0748380718946779 CDK13 other 3.64635014523832e-08 1 0.000744616024960224 5.68821086227768 -1.79368723327826 1.20264508417544e-06 114.049548485191 24.0741941590149 4.73741915230352 4.87965248638221e-06 -139.728520942274 110.275784603497 -1.26708253715606 0.207038594488651 FOXJ2 other 0.0108959644626295 1 0.0508996550854528 4.73741915230352 -1.26708253715606 1.47924731422997e-08 4018.90143567896 694.99615803218 5.78262396019299 4.12866785509632e-08 -2492.63779745838 3024.20765113924 -0.824228388060386 0.411118477770874 YBX1 essential 0.000156119761543831 1 0.000489123280793261 5.78262396019299 -0.824228388060386 0.0106804898174152 16.6252245107163 24.7857136757961 0.670758354113937 0.50337921327643 -236.90103130606 98.4289195784338 -2.40682344498645 0.0172758542965036 PDE4A other 1 1 1 0.670758354113937 -2.40682344498645 0.00111793759540126 128.894824499618 66.8165009867453 1.92908671654608 0.0555354061824516 -459.285936491167 199.73685648267 -2.29945511599165 0.0228053957375747 PPP2R5A other 1 1 1 1.92908671654608 -2.29945511599165 7.2985084621186e-12 249.259858227803 49.0095402877938 5.08594564984897 1.05000880102081e-06 -407.9502431532 158.583801778654 -2.57245846409082 0.0110430360645068 ELAVL1 other 9.0151176524089e-08 1 0.0114629460807442 5.08594564984897 -2.57245846409082 0.645565278834146 6.51362204951905 18.5962463360147 0.350265420871757 0.726624416264085 -62.0436862193716 85.3978504762559 -0.726525151082371 0.468634238485848 TIE1 other 1 1 1 0.350265420871757 -0.726525151082371 7.52719296231608e-06 254.104688063469 61.043417390999 4.16268778721647 5.24882183952705e-05 -170.872124053371 153.290240271151 -1.11469669400426 0.266739802041751 DIP2B other 0.0628821700071886 1 0.49564624630654 4.16268778721647 -1.11469669400426 4.12542855152304e-13 596.095434144962 96.7729172792663 6.15973405477439 6.15173803747219e-09 -674.892928137259 246.442680536869 -2.73853914698144 0.0069039299902863 SMARCD1 other 5.29870043157620e-09 1 7.55802535283833e-05 6.15973405477439 -2.73853914698144 7.41778317787681e-15 678.266814830389 79.6479846759208 8.51580636459523 1.49576468846404e-14 -160.105026053789 347.177516259014 -0.461161851086985 0.645341696635145 KDM4A other 9.91980144377465e-11 1 2.07642054052578e-10 8.51580636459523 -0.461161851086985 2.27641660276277e-29 490.861447078214 35.5571908181711 13.8048432900207 1.69057830706181e-28 -424.16978923649 248.772424851307 -1.70505147220404 0.090254960296595 NFYC other 3.29693416578133e-25 1 2.45100042957821e-24 13.8048432900207 -1.70505147220404 0.000187858712026138 51.8517278269287 12.8190882627874 4.04488421984341 8.30114391760647e-05 -3.75358046494255 57.3232764185619 -0.0654809128064268 0.947877146387606 ZMYND12 other 1 1 0.765863537838373 4.04488421984341 -0.0654809128064268 0.371904871658963 -9.56242235250978 7.98209774611792 -1.19798361992754 0.233284199847554 8.61305296582265 27.5714037707621 0.312390803073883 0.755285730658144 SLC9A3 other 1 1 1 -1.19798361992754 0.312390803073883 0.0449902224671913 44.164657810529 60.8314739694703 0.726016565580739 0.468909539322171 -249.00533681991 135.702242163777 -1.83493900210867 0.0684072360650803 NGEF other 1 1 1 0.726016565580739 -1.83493900210867 0.00317233114093136 122.03526517851 41.1122467105628 2.96834337558 0.00346994729283495 -196.109726660383 152.555833773731 -1.28549477138482 0.200536768401946 ASPM other 1 1 1 2.96834337558 -1.28549477138482 0.533123628390498 -71.6675647888823 67.6005777483804 -1.06016201600584 0.290797972274165 -105.200275345364 135.962858174577 -0.773742746789613 0.440317096018892 SPI1 other 1 1 1 -1.06016201600584 -0.773742746789613 1.22394188911097e-06 98.7605573134634 21.6733095161034 4.55678249046753 1.0423540491983e-05 -56.471746452996 64.4422988610662 -0.876314896443184 0.382206263326241 ZNRD1 essential 0.0110778980383434 1 0.10565300642674 4.55678249046753 -0.876314896443184 0.0233848623310366 235.034837037719 98.5564422188961 2.38477396044493 0.018298302517843 -6.20890185443506 160.956913331693 -0.0385749311782591 0.969278928388578 MPPED2 other 1 1 1 2.38477396044493 -0.0385749311782591 7.52278154849813e-12 134.342882124352 17.6275744462336 7.62117797511596 2.39803813532379e-12 -2.77169041450775 78.1005734433202 -0.0354887332103809 0.971735988954393 ZBTB11 essential 9.28762609977579e-08 1 3.23807089412772e-08 7.62117797511596 -0.0354887332103809 2.38407726247451e-13 202.397845741149 26.6673000560719 7.58973894303427 2.73068809538974e-12 -18.5778748861234 46.5377206647753 -0.399200360927542 0.690291537764426 ATXN3 other 3.08118145402206e-09 1 3.6826059654426e-08 7.58973894303427 -0.399200360927542 4.77143777792414e-16 315.878122415447 42.5805565395299 7.41836528421605 7.13840145300742e-12 -198.785271022254 74.5085294190633 -2.66795322055294 0.00843753304838617 GOLGA5 other 6.50967256042191e-12 1 9.54761194339742e-08 7.41836528421605 -2.66795322055294 2.52452402944121e-07 702.752254168947 136.76717242515 5.13831090975833 8.23220787341447e-07 27.5075172735194 238.93262731633 0.115126668059031 0.908493729918926 FGFR2 og 0.00242632004469594 1 0.00903896424500909 5.13831090975833 0.115126668059031 4.24377099541494e-06 56.6191122071516 16.1451317273204 3.50688450013337 0.000592340830903718 -125.984134812988 48.7210789233718 -2.58582399234498 0.0106292180289953 LRRC40 other 0.0364013196596564 1 1 3.50688450013337 -2.58582399234498 4.85389773206826e-05 174.755323848291 58.8256403343542 2.97073389860296 0.00344771036924291 -111.432913433915 87.413979279203 -1.27477223154428 0.204309885158751 ISOC1 other 0.370158241047526 1 1 2.97073389860296 -1.27477223154428 2.06206918302993e-06 165.250485436893 35.5320212378143 4.65074824567053 7.13440661520192e-06 -24.8805825242716 56.8915969490099 -0.437333171479985 0.662490471397204 EML1 other 0.0182719950308282 1 0.0733202967844301 4.65074824567053 -0.437333171479985 7.03744154533661e-11 119.155395227146 19.8313340243017 6.00844073732665 1.3764536041348e-08 15.3192737651628 38.3614478706494 0.399340343378533 0.690214252830397 TRMT11 other 8.38651908957764e-07 1 0.000166495827956145 6.00844073732665 0.399340343378533 5.32182792577399e-14 280.98452891469 40.3972461123696 6.95553672478314 9.09330642635734e-11 -188.446094304579 111.024715347548 -1.69733463143476 0.0916275233888105 THUMPD1 other 6.99713935680764e-10 1 1.18622182331832e-06 6.95553672478314 -1.69733463143476 2.08817209706657e-07 51.2112091333677 24.1684655311521 2.11892679191233 0.0356701087751944 -127.594533817679 36.2662083944096 -3.51827608858464 0.000568351377960734 MSANTD3 other 0.00202385639647692 1 1 2.11892679191233 -3.51827608858464 0.690907638905356 2.66749143123693 18.146991910555 0.146993586837134 0.883342681706546 -26.2266682891543 37.3429992749562 -0.702318206849096 0.483614448182582 KIF26A other 1 1 1 0.146993586837134 -0.702318206849096 8.95792216604297e-08 179.830367036794 36.3388302942838 4.94871094034862 1.95022947781515e-06 -59.966548316335 59.9680145204749 -0.999975550230374 0.318901222731185 ATG2B other 0.000895165162052674 1 0.0209357134443456 4.94871094034862 -0.999975550230374 2.93031834134107e-09 311.837266530502 54.8801017257528 5.68215540286017 6.90901655698243e-08 -219.112557521471 193.392296009367 -1.13299527459386 0.259060785559889 ARFGEF1 other 3.22715958931892e-05 1 0.000809460379816062 5.68215540286017 -1.13299527459386 0.0219706025537938 43.3044169761701 17.7303828094835 2.44238477203142 0.0157371179154114 -89.0534496379296 107.623552680708 -0.827453168193848 0.409277438862957 ZFAT other 1 1 1 2.44238477203142 -0.827453168193848 0.0130425211046582 58.7886997285961 23.6132488772707 2.48964892692865 0.0139164702726745 -49.6006661732052 88.5056177566607 -0.560423930485162 0.576055190593825 MTFR1 other 1 1 1 2.48964892692865 -0.560423930485162 0.102784456845054 57.7191214087727 28.0148523593967 2.06030432244676 0.04103046451776 -1.38196757717078 92.2316375425761 -0.0149836608564261 0.988064361365154 STAG3 other 1 1 1 2.06030432244676 -0.0149836608564261 1.00236443596156e-10 106.077576964937 34.9965240389641 3.03108894034257 0.00285938635538656 -145.210087203858 65.1136692597111 -2.23010143422691 0.0271867731476863 FECH other 1.18699996506568e-06 1 1 3.03108894034257 -2.23010143422691 1.8790421047016e-05 137.791982182628 39.5299619339982 3.4857605583505 0.000644924559683076 -117.199554565701 69.084667811368 -1.69646259117448 0.0918864826689767 MYO9A other 0.150774338481256 1 1 3.4857605583505 -1.69646259117448 0.000981453538967269 513.671808709836 152.662159264607 3.36476184526839 0.000968470602428142 -297.453206039125 663.737098064598 -0.448149134508941 0.654679529350231 PFKP other 1 1 1 3.36476184526839 -0.448149134508941 0.000159573880632107 145.092825843053 47.1474702334546 3.07742547213274 0.00248285008554098 -262.057173804131 173.1382599821 -1.51357171910601 0.132238690976867 IDI1 other 1 1 1 3.07742547213274 -1.51357171910601 0.0364645288193044 -25.3356370780766 90.3722199645247 -0.280347623285364 0.779577544955902 -510.841957635524 210.660574180564 -2.42495284000159 0.0164378273894814 SP100 other 1 1 1 -0.280347623285364 -2.42495284000159 0.077333030099961 290.810135158501 171.695322070107 1.69375689245486 0.0923331046633439 1521.22182362155 745.204303385533 2.04134868345566 0.0429232091124421 KLF6 other 1 1 1 1.69375689245486 2.04134868345566 0.000463114937080574 113.13055920126 42.1286478523009 2.68535936870999 0.00804479865161772 -43.0899450447385 67.423554438552 -0.639093346584234 0.523717845285365 PLPP1 other 1 1 1 2.68535936870999 -0.639093346584234 4.31326828293302e-06 1241.03576284439 245.955885901184 5.04576565954999 1.28136544165644e-06 347.908116259094 426.581530407932 0.815572385251644 0.416029347198922 NEO1 other 0.0369431428433213 1 0.0139053777728556 5.04576565954999 0.815572385251644 0.00226970090579112 900.618383258104 380.821247266758 2.36493732879152 0.0193128551143012 -1770.37890393471 1270.86078585557 -1.39305494641009 0.165664240002961 TRAM1 other 1 1 1 2.36493732879152 -1.39305494641009 2.55894478440072e-06 472.039698078744 111.453248677888 4.23531573712124 3.97883827550381e-05 -793.840935559232 492.840378741972 -1.61074654147778 0.10935139914479 TNFRSF1A other 0.0224342689248411 1 0.379740325014084 4.23531573712124 -1.61074654147778 0.00320481668313421 49.8542883828148 19.0366481714456 2.6188585266599 0.00971001618183785 -135.977842693056 73.0444765194719 -1.86157597634104 0.0645812946438915 CACNB1 other 1 1 1 2.6188585266599 -1.86157597634104 1.61955604492604e-06 67.0759591824075 17.1955124970847 3.90078278817101 0.000142530885585278 -148.646009739152 55.9691560848009 -2.65585583448736 0.00873778058226711 EVI5 other 0.0144934070460431 1 1 3.90078278817101 -2.65585583448736 0.000128812727724773 22.0179035466586 13.9593017699899 1.57729261172599 0.116834842627829 -76.0586211222423 24.2708317554821 -3.1337459667019 0.00207634809826274 STOML1 other 0.93080077053921 1 1 1.57729261172599 -3.1337459667019 0.00302432149741798 6081.6612263926 2346.60829191544 2.5916814695257 0.0105073971829222 -4579.87038820229 4097.18450816707 -1.11780916360322 0.265459708670924 PKM essential 1 1 1 2.5916814695257 -1.11780916360322 5.82950218658599e-14 145.382393814896 30.1356421892419 4.82426732113231 3.36759613948551e-06 -127.250213917698 48.1249872445072 -2.64416099003168 0.00904294736610591 DHX29 other 7.65763407229936e-10 1 0.0355449772522695 4.82426732113231 -2.64416099003168 6.01404430590055e-09 199.464025856167 40.3016737895516 4.94927399039887 1.93439563697271e-06 -383.55104629379 129.918707622115 -2.95223877541482 0.003649127287948 DNTTIP2 essential 6.49757346809495e-05 1 0.020771540349813 4.94927399039887 -2.95223877541482 1.72665712580668e-12 117.060670964458 15.4155834989284 7.59365812994339 2.866652410203e-12 54.2046399185682 35.1631031536896 1.54152037383198 0.125255915132959 METTL22 other 2.17593330994158e-08 1 3.86424744895365e-08 7.59365812994339 1.54152037383198 8.74972649653818e-14 625.627422135969 87.1716614313208 7.1769587944458 3.99370117810766e-11 -121.239030892377 159.587769478607 -0.759701268389675 0.448729013332603 TP53BP1 other 1.14358925309754e-09 1 5.26130193203903e-07 7.1769587944458 -0.759701268389675 1.66201897495609e-12 106.152404115752 17.7859992463587 5.96831263992572 1.53964287584059e-08 -145.464156701138 54.9177660086635 -2.64876318308707 0.00890411724644413 RRP15 essential 2.09580592741963e-08 1 0.000185819498685201 5.96831263992572 -2.64876318308707 2.39351056053443e-05 418.012484685841 457.380905291321 0.913926401058642 0.362473855540191 -3851.24354471734 989.169403361861 -3.89341151437583 0.000158298173282755 RHOA other 0.189996868295223 1 1 0.913926401058642 -3.89341151437583 1.67047031223743e-13 429.099650844579 50.7857887374043 8.44920718005 1.93251357771091e-14 117.623709016178 216.493528875255 0.543312816910816 0.587689952325585 DHX8 essential 2.16743523012806e-09 1 2.68039633228503e-10 8.44920718005 0.543312816910816 4.12539085687025e-10 224.298136956196 45.1850304859558 4.96399215722364 2.03197595933781e-06 -160.337889216323 101.032258650185 -1.58699697857372 0.114835639535648 PRKCZ other 4.75080011077178e-06 1 0.0217909101879386 4.96399215722364 -1.58699697857372 1.59462857068381e-13 487.841364452424 68.1312491056479 7.16031734125338 3.03562851745867e-11 -298.878539796531 206.434904214281 -1.4478101023376 0.149689832515383 IARS2 essential 2.06998734760466e-09 1 4.00824389445243e-07 7.16031734125338 -1.4478101023376 6.95731974028196e-06 47.7984069551233 11.15113896271 4.28641478820805 3.23386621150162e-05 0.0117928874147397 24.1996845232488 0.000487315750063197 0.999611825793921 SYT1 other 0.0582953821038225 1 0.312294460044711 4.28641478820805 0.000487315750063197 0.657613413414129 -4.47209117544816 12.0008740027741 -0.37264712340238 0.709937109366912 -23.8152323252388 26.2704992271237 -0.90653900861732 0.366104577550026 NAV3 other 1 1 1 -0.37264712340238 -0.90653900861732 7.74729199696149e-16 202.18369850254 23.1461682729463 8.73508289226673 3.56965568356452e-15 -76.0770387329358 72.9456789398162 -1.04292728285802 0.298595479540019 ROGDI other 1.05339929282685e-11 1 4.98466719652949e-11 8.73508289226673 -1.04292728285802 5.4969419168139e-12 341.050203953562 53.7467445100494 6.34550440333727 3.6442244304982e-09 -29.5470662064643 119.402397054001 -0.247457898128304 0.804956653050354 ROCK1 other 6.81620797684923e-08 1 4.51264311228592e-05 6.34550440333727 -0.247457898128304 8.08299313143621e-14 292.430941373602 70.2561833853828 4.16235165763992 5.41534471623264e-05 -279.069623894699 111.376540309423 -2.50564098255696 0.0133437622680488 CBFB other 1.05725550159186e-09 1 0.510179625716278 4.16235165763992 -2.50564098255696 1.41151945527322e-05 168.859543727827 85.9861679738013 1.96379891913867 0.0516550024564605 -610.189419004666 185.104989893919 -3.29645040554745 0.00125796501961918 HYAL2 other 0.114756531713713 1 1 1.96379891913867 -3.29645040554745 9.38431635438024e-09 199.387685403967 36.7005978876382 5.43281845201564 2.26672945839174e-07 -56.3617437404444 81.6230831868364 -0.690512310242332 0.490968358944224 HDAC4 other 0.00010024326729749 1 0.0025795381236498 5.43281845201564 -0.690512310242332 0.00283581286408579 19.0374677581812 21.1006317002597 0.90222264568254 0.368581975096993 -122.692672327479 45.4239595701244 -2.70105630351464 0.00781889076602889 RASSF1 other 1 1 1 0.90222264568254 -2.70105630351464 0.18839012487716 95.1910840617365 64.2751416649873 1.48099376517734 0.140793002047127 -5.31898837849626 114.395512095388 -0.046496477712002 0.962978962081563 FGFR3 og 1 1 1 1.48099376517734 -0.046496477712002 0.0176538869626395 159.952050837666 72.5567465467118 2.2045096900078 0.028952680557231 598.920999422297 287.916293147886 2.08019140866983 0.0391432085993191 IFI35 other 1 1 1 2.2045096900078 2.08019140866983 4.03095183321811e-09 166.81248084976 25.3051023613352 6.5920492423947 6.3388605296642e-10 70.5866612194867 101.2308828697 0.697283864552907 0.486663020858163 HEATR6 other 4.39978392595757e-05 1 8.0509867587265e-06 6.5920492423947 0.697283864552907 2.25030606731324e-09 341.995342671873 69.3451335227002 4.93178576921941 2.06721855044364e-06 -1107.43816501272 276.335782604138 -4.00758148140071 9.47701751221457e-05 COASY essential 2.49198893894268e-05 1 0.022152313986554 4.93178576921941 -4.00758148140071 9.92618342547898e-06 165.297804320108 35.777962985677 4.62010104896921 8.08639483054584e-06 -189.01612540314 140.829661183185 -1.34216133032712 0.181531948031895 PLEKHH3 other 0.0820399060115837 1 0.0827723374854672 4.62010104896921 -1.34216133032712 1.72529519759815e-05 221.292759491076 53.4702873859711 4.13861174700056 5.73370969492993e-05 -121.559047753277 106.076677104998 -1.14595452149161 0.253591539947305 MEF2A other 0.138972528166531 1 0.538395340353921 4.13861174700056 -1.14595452149161 0.00454645194791398 108.461975383652 35.9645388536788 3.01580331183804 0.00303055355771786 28.6414933672108 67.7001112577143 0.423064199380428 0.67287956141992 INPP5A other 1 1 1 3.01580331183804 0.423064199380428 0.000458489358271711 129.990245949309 33.6693744823052 3.86078589068011 0.000165185897488015 154.339529302643 129.556197859618 1.19129406275012 0.235347509405022 PRR11 other 1 1 1 3.86078589068011 1.19129406275012 0.0440261756615921 395.101456012355 160.848150404397 2.45636306677452 0.0151609045544909 113.573517593483 296.542305555003 0.382992630278911 0.702260301960862 ATP11A other 1 1 1 2.45636306677452 0.382992630278911 0.0011677838434645 982.143025398647 342.072959643326 2.87115072299988 0.00468604448246724 -1788.62375430884 1139.02998132162 -1.57030436743507 0.118465492811784 LAPTM4A other 1 1 1 2.87115072299988 -1.57030436743507 0.000997069572330466 148.552235379641 39.1799171898606 3.79154031030176 0.000215458053531816 162.716312436631 174.418549350891 0.93290715375279 0.352347432656085 TTC7A other 1 1 1 3.79154031030176 0.93290715375279 1.14830957526223e-11 556.123085569763 102.22508468562 5.44018219481106 2.66302521757258e-07 -676.177238198021 222.69815424137 -3.03629475736539 0.00291106644371864 IP6K2 other 1.40955000363439e-07 1 0.00301694126898798 5.44018219481106 -3.03629475736539 4.25445907495594e-05 135.736489095134 29.8247272155558 4.55113933194124 1.08077220800621e-05 -17.544527884812 132.966204954758 -0.131947271043658 0.895199355994013 STON1-GTF2A1L other 0.32640210023062 1 0.109438993782709 4.55113933194124 -0.131947271043658 8.16870238519958e-11 85.4618047058002 12.4877593410575 6.84364603542742 1.80996497377713e-10 -54.4208824249205 53.0301097326955 -1.02622609493428 0.306426164870155 SRBD1 essential 9.70605217409414e-07 1 2.34064670408858e-06 6.84364603542742 -1.02622609493428 1.31470236960523e-07 147.072412442823 66.2972364939283 2.21837922997427 0.0279921548050479 -214.619679763846 91.5022201080187 -2.34551336033691 0.0202759699171315 KIF2A other 0.00129550771500899 1 1 2.21837922997427 -2.34551336033691 0.296884405922527 12.9147479679822 10.1607114265875 1.27104760934242 0.205761107618655 -16.0890842785178 30.8556651789183 -0.52143047914295 0.602867945915837 RASGRP2 other 1 1 1 1.27104760934242 -0.52143047914295 1.6823915577278e-11 479.449111655375 63.0146512536188 7.60853392214627 2.51442724467764e-12 141.311457147304 268.290211718328 0.526711191743602 0.599147114714615 PSME4 other 2.05184474380483e-07 1 3.39422533759034e-08 7.60853392214627 0.526711191743602 3.01678377094867e-10 156.417039700594 23.2483163883611 6.72810181553199 3.28736144756327e-10 208.462831144052 94.9023186845446 2.19660419295953 0.0295632499732514 IFT80 other 3.49584903377532e-06 1 4.21045254203904e-06 6.72810181553199 2.19660419295953 7.93404096681647e-18 312.590809551339 39.2953480569183 7.95490624230022 3.6083617028535e-13 -259.540699473847 136.769747768147 -1.89764698487141 0.0596140254600301 SIRT2 other 1.10386311971318e-13 1 4.92974375843845e-09 7.95490624230022 -1.89764698487141 0.000879391410200558 162.077333467128 42.5477374650674 3.80930557353836 0.000200450623130961 198.165780275283 179.294330241559 1.10525402564766 0.270762181498981 ERLEC1 other 1 1 1 3.80930557353836 1.10525402564766 0.259053111134455 12.7583751091063 27.9704191248522 0.456138145522826 0.648977822331282 -118.52441275751 85.0072117627269 -1.39428655874912 0.165378606982254 PPP2R5B other 1 1 1 0.456138145522826 -1.39428655874912 0.930262867638046 -11.8692863986154 69.3828013538619 -0.171069575846043 0.86440920367387 -78.7934450041723 210.699073900299 -0.373961990176837 0.70898264145836 PYGM other 1 1 1 -0.171069575846043 -0.373961990176837 0.369150124482887 -55.0024077046561 168.871406394542 -0.32570586625039 0.745080595932754 -373.741974317818 275.731378989026 -1.35545680614281 0.177218802847048 PITX1 other 1 1 1 -0.32570586625039 -1.35545680614281 0.00218449309937017 105.885605116108 143.283324238928 0.738994615587933 0.461072816496178 -396.946923966957 209.156172458853 -1.89784943614346 0.0596500354462898 MAST4 other 1 1 1 0.738994615587933 -1.89784943614346 0.953118683348215 0.297617205632064 14.8108961515868 0.0200944765654966 0.983994890109725 11.8785639078733 41.1860869370368 0.288412053469237 0.773432166990359 ADGRF5 other 1 1 1 0.0200944765654966 0.288412053469237 0.0626600904740584 97.6520766108046 43.4038957394455 2.24984589394952 0.0258666112853725 139.801589986469 178.260069292651 0.784256342663903 0.434086601203149 SDK2 other 1 1 1 2.24984589394952 0.784256342663903 1.20239901969473e-16 339.567477682479 40.8107388407177 8.32054227216502 3.98245743751393e-14 -171.784818250773 126.813336231312 -1.35462738664514 0.177482496014314 NUP133 essential 1.65197601315859e-12 1 5.49778249248798e-10 8.32054227216502 -1.35462738664514 1.98227677046962e-12 2135.54537283758 301.151981403021 7.0912545980551 4.42851022715807e-11 -2340.5981810919 1135.3656682885 -2.06153686558112 0.0409220232669849 NUCKS1 other 2.49350594957373e-08 1 5.82304809769015e-07 7.0912545980551 -2.06153686558112 6.4680220498013e-08 827.158096209654 188.437199685479 4.38956903196538 2.25197549550546e-05 -38.6696544415485 279.058928140837 -0.138571643986364 0.889992130721572 VPS35 essential 0.000653528947911923 1 0.220783677579355 4.38956903196538 -0.138571643986364 0.000412155679840828 147.33711163663 92.3562111225268 1.59531351325318 0.112834543185294 -224.803508199676 136.910217487554 -1.64197758447146 0.102776771095855 DNAJA2 other 1 1 1 1.59531351325318 -1.64197758447146 0.00279055334368234 -24.0747849106551 34.1775774583642 -0.704402906846851 0.482303965219013 -251.128155431597 77.7783715247775 -3.22876592179094 0.00153565817422042 KCNAB2 other 1 1 1 -0.704402906846851 -3.22876592179094 0.855339236548135 6.56251770583841 14.6048784702532 0.449337371701159 0.653841220988493 -17.0952586983955 88.2143762713922 -0.193792207358604 0.846602531252527 ABCC9 other 1 1 1 0.449337371701159 -0.193792207358604 0.669628334063187 -30.9796121540177 37.4278155139399 -0.827716278084126 0.409112017431111 17.7719899610723 113.083644118855 0.157157917040535 0.875326251032266 GAL other 1 1 1 -0.827716278084126 0.157157917040535 0.00884811132119312 37.6430837399355 16.0327203488401 2.34789124496011 0.020143274103697 -88.9695551226129 69.3391482345463 -1.28310712473226 0.201369748311501 CLEC2D other 1 1 1 2.34789124496011 -1.28310712473226 0.0688803122953248 13.5659292435512 25.385467537963 0.534397454892798 0.593873886471241 -70.6360846183719 39.0762843601669 -1.80764588483689 0.0727061903484107 RORA other 1 1 1 0.534397454892798 -1.80764588483689 0.0463898610022258 29.9667481733483 13.9289638249099 2.15139823392729 0.0330565357837832 1.96278076313446 24.063641823622 0.0815662391221142 0.93510111279974 DRD4 other 1 1 1 2.15139823392729 0.0815662391221142 0.00338350157298484 125.260026790199 52.3919204396439 2.39082716837036 0.0180102134824405 -309.991069933582 179.023606926597 -1.73156532401162 0.0853406280433243 TGFBR3 other 1 1 1 2.39082716837036 -1.73156532401162 1.57295495463711e-12 47.0428252497628 6.47423243358745 7.26616255012886 1.69611508890817e-11 -31.3915834124016 22.1225034817575 -1.4189887432174 0.157910054781185 KIAA1107 other 1.98519553874641e-08 1 2.25108394599892e-07 7.26616255012886 -1.4189887432174 0.0352658765115556 41.0428874508999 22.809635223892 1.7993662348405 0.0740693599635433 -28.0089754206485 50.9575545243221 -0.549653053057713 0.583414763452614 HES2 other 1 1 1 1.7993662348405 -0.549653053057713 0.189984560783485 120.317765601173 98.6498869084564 1.21964423246449 0.22444051799456 -440.762613365242 387.267545563799 -1.13813465242372 0.256809167382747 ATP1B3 other 1 1 1 1.21964423246449 -1.13813465242372 0.594866612648381 -6.11980057820514 14.2254633364954 -0.430200439412388 0.66765916182375 -21.7496705803685 21.3038590037126 -1.02092632966536 0.30891149963049 NEDD4 other 1 1 1 -0.430200439412388 -1.02092632966536 1.32222609369075e-08 56.1846158275038 17.2202124481081 3.26271327934032 0.00135922782690636 -91.742954198693 25.6678124792953 -3.57424125147776 0.000469418576064989 PIGB other 0.000140023743321851 1 1 3.26271327934032 -3.57424125147776 4.51512666022313e-06 269.461703267275 56.5871607879691 4.76188767054318 4.43506190607257e-06 30.8560867753951 84.7602435892604 0.364039618915214 0.716334313845601 MAPK6 other 0.038568211931626 1 0.0464306630946737 4.76188767054318 0.364039618915214 4.68567176356961e-13 257.901446170327 33.1607594386997 7.77730819606465 1.04531030354896e-12 47.0504464782429 49.6705261138784 0.947250817725818 0.34501448154769 GNB5 other 6.00937403677802e-09 1 1.41890420603736e-08 7.77730819606465 0.947250817725818 0.0131784374234911 -26.3571174604981 35.8645714998611 -0.734906799614217 0.463506695390033 -156.216363498452 53.3361424264598 -2.92890254884564 0.00391521669846568 RAB27A other 1 1 1 -0.734906799614217 -2.92890254884564 1.16174507132604e-07 193.352186660152 50.7454447622992 3.81023730436985 0.000206107482440405 -136.247055949181 76.0415652965248 -1.791744494184 0.0753034857476493 HDHD5 other 0.00114954674807712 1 1 3.81023730436985 -1.791744494184 4.68114116063864e-11 241.756815571541 66.1668160695865 3.6537471489831 0.000362816343077296 -367.257432502107 105.483897319663 -3.48164451479408 0.000662528643607973 UFD1 other 5.61409259395392e-07 1 1 3.6537471489831 -3.48164451479408 1.97175867617559e-11 456.534456172703 64.5295637545819 7.07481082483356 4.75489061026107e-11 -25.962813563094 279.540287533069 -0.0928768221289844 0.926120589405106 LRP6 other 2.39864442956761e-07 1 6.24982821812715e-07 7.07481082483356 -0.0928768221289844 1.78791472225656e-07 424.59234739243 80.7459273062853 5.2583747757564 4.95810747755589e-07 87.0280859782731 139.496454857598 0.623873101772469 0.53366488773619 PHRF1 other 0.00174303806272792 1 0.00552828983747482 5.2583747757564 0.623873101772469 0.157017755110638 377.63886885144 198.778816242187 1.89979433417762 0.0593540248900708 413.755490952056 807.096019210084 0.51264717097354 0.608942324308028 PFN2 other 1 1 1 1.89979433417762 0.51264717097354 3.22718929170815e-06 170.052310776858 54.867754733387 3.09931236667464 0.00229686689648799 -204.991273782433 87.6897994074379 -2.33768665417936 0.0206573516243206 PTPN3 other 0.0279894127269848 1 1 3.09931236667464 -2.33768665417936 0.0219724593099862 -6.29390164409336 31.2352641089282 -0.201499869575117 0.840573642415138 -102.923075251684 47.2535193185502 -2.17810391132665 0.0309195835683368 DAPP1 other 1 1 1 -0.201499869575117 -2.17810391132665 1.69793029073776e-07 466.871028923661 130.34690774702 3.58175761123367 0.000454710171290542 -451.165280112648 204.434668335626 -2.20689222520692 0.028772978308006 SLC44A1 other 0.00165802892890542 1 1 3.58175761123367 -2.20689222520692 1.92655597737237e-07 144.591945288754 29.5145117259844 4.89901193796325 2.37675841160233e-06 -17.3834853090169 42.9899232318554 -0.404361859761028 0.686496964407952 TMEM260 other 0.00187299772120142 1 0.0253505052181505 4.89901193796325 -0.404361859761028 8.99273852441958e-16 338.344834479451 38.1628824716936 8.86580919904071 2.15215517816369e-15 -185.364345114344 174.198474247127 -1.06409855720881 0.289005488259865 SMG6 essential 1.22130381900142e-11 1 3.01043466321536e-11 8.86580919904071 -1.06409855720881 5.6551471455709e-06 183.326911850554 51.7476293957116 3.54271130854445 0.00052264405873172 -110.425017837452 73.0142166431115 -1.51237694402999 0.132461186708432 EXOC5 essential 0.0478199242629476 1 1 3.54271130854445 -1.51237694402999 0.000109256321749337 44.1546273348243 11.9856695407998 3.68395167116196 0.000325730001750936 -0.0919315438198887 19.1076918952772 -0.00481123226833122 0.996167959405833 CLTCL1 other 0.798008174057161 1 1 3.68395167116196 -0.00481123226833122 0.102036779841281 103.79927450888 48.2802279444364 2.14993339775318 0.0332911833202022 62.4519055919349 72.0570276872874 0.866701106004028 0.387599436272194 FSTL3 other 1 1 1 2.14993339775318 0.866701106004028 4.08840219117271e-16 1299.05227688859 169.618839496714 7.65865561126985 2.580033853607e-12 -162.873940921337 268.804743803275 -0.605919146428965 0.545529004005305 DGCR2 other 5.57903363007429e-12 1 3.48227169221336e-08 7.65865561126985 -0.605919146428965 0.000543201693345064 186.542507184246 72.5512520249628 2.57118246725863 0.0111862928579553 -164.995741272907 108.280921579877 -1.52377481522627 0.129836900516234 RNF126 other 1 1 1 2.57118246725863 -1.52377481522627 4.87909708775487e-10 333.09648706385 48.4360459590726 6.87703714182841 1.54188222383476e-10 6.79507872458212 221.505998780283 0.0306767255153317 0.975568131782091 MNT other 5.59730017907239e-06 1 1.99797098564509e-06 6.87703714182841 0.0306767255153317 7.73172881984248e-10 194.965286400691 28.1278087565324 6.93140685391684 1.13217605092309e-10 58.0304486314311 119.662560107527 0.484950753011516 0.628414060929623 ZXDC other 8.77937807493113e-06 1 1.47250817183057e-06 6.93140685391684 0.484950753011516 2.99331821218671e-10 118.349877040018 16.6880486134376 7.09189431199999 4.25194792720128e-11 59.8667560921073 73.4792338627563 0.814743879936551 0.41645308134104 JMJD6 essential 3.46925580792439e-06 1 5.59768944616049e-07 7.09189431199999 0.814743879936551 8.05072367154352e-14 210.158411685695 24.1308100657442 8.70913206449018 2.92091664557192e-14 154.481615177972 68.1761114811985 2.26592000954138 0.0253608139836321 POLB other 1.05311516347461e-09 1 4.04021190415508e-10 8.70913206449018 2.26592000954138 0.611861392518026 -72.7312765481775 86.9438237384754 -0.836531836544838 0.404127212863827 192.550776883526 382.822803635499 0.502976246594916 0.615685839791075 ST6GALNAC1 other 1 1 1 -0.836531836544838 0.502976246594916 0.00574687843710646 76.2363291966037 23.3697821070035 3.26217543867288 0.00135477224283216 -7.56032658393226 94.8109218110832 -0.0797410935313623 0.936544084441049 WIPI1 other 1 1 1 3.26217543867288 -0.0797410935313623 2.29694550136808e-11 126.053106866202 17.4441856513355 7.22608147985125 2.34400732918212e-11 50.6362481605907 38.7550756444518 1.30657074766515 0.193358273763486 FRMPD1 other 2.78803244956058e-07 1 3.10346570383713e-07 7.22608147985125 1.30657074766515 1.60103103743733e-13 469.547095469019 68.937178080859 6.81123174085064 2.97165811492983e-10 -254.035114370016 180.139624206156 -1.41021230331474 0.160794018960743 GBA2 other 2.07813828659365e-09 1 3.8117458640205e-06 6.81123174085064 -1.41021230331474 0.000121827642792628 703.468096372782 183.159540575273 3.84073957689185 0.000179228386063851 -67.8009332803819 293.885132307051 -0.230705557467751 0.817851759793654 NDST1 other 0.884590514317272 1 1 3.84073957689185 -0.230705557467751 0.213477335441024 69.3507809844162 52.2267634472952 1.32787820662871 0.186183162359337 -118.464640997656 167.602675095622 -0.706818318562451 0.480747496129713 ASNS other 1 1 1 1.32787820662871 -0.706818318562451 7.06319104707591e-13 205.769884284155 25.4753840309325 8.0772044116904 7.64349502730522e-13 99.4281406982061 74.6519631771942 1.33188916227431 0.185553361820992 AP3M2 other 9.0062749041265e-09 1 1.03974462856433e-08 8.0772044116904 1.33188916227431 0.0163845412630387 -0.0759087776079094 13.7174206266007 -0.00553375008860687 0.995592180803466 -44.9504255446673 21.137993507248 -2.12652281917176 0.0351185058691134 CNGB1 other 1 1 1 -0.00553375008860687 -2.12652281917176 3.54581947669313e-05 701.573753632909 150.202256833985 4.67086026815392 6.40201529840154e-06 296.581209479099 661.356340233278 0.448443889378133 0.654451156648399 ST6GALNAC2 other 0.275297424170455 1 0.0661008079559959 4.67086026815392 0.448443889378133 3.2203985333197e-13 80.4539553413982 10.6030603967258 7.58780506109746 2.82555405721074e-12 -37.917315549234 34.1017499456206 -1.11188767760299 0.267908067479089 TESK2 other 4.14561903194244e-09 1 3.80941197993152e-08 7.58780506109746 -1.11188767760299 9.24748820123845e-11 187.645113669915 53.6827024333761 3.49544835047742 0.000622591634194287 -197.551569148474 84.3849438268524 -2.34107602837095 0.0205444701260489 CFAP20 other 1.09675210066688e-06 1 1 3.49544835047742 -2.34107602837095 4.57005014636334e-15 446.947741364039 69.2117046326993 6.45769012244321 1.39494040706783e-09 -30.6943364768409 108.795301705226 -0.282129246352983 0.778233298429575 CSNK2A2 other 6.13437831146351e-11 1 1.75260312744002e-05 6.45769012244321 -0.282129246352983 2.84515789645095e-07 133.118082521332 25.6656961499598 5.18661491757514 6.69340617382326e-07 -3.10291149663773 44.5850787355919 -0.0695952902772537 0.944606663122953 PTPN21 other 0.00271968643321746 1 0.00739353645960517 5.18661491757514 -0.0695952902772537 4.9745297426112e-07 51.5468348516703 15.592043288987 3.3059704809875 0.0011809463479179 -185.546017285681 53.7239367836064 -3.45369361208651 0.000716620309498125 EIF2B3 essential 0.00465635063999643 1 1 3.3059704809875 -3.45369361208651 0.00129069749778061 351.861795075456 108.973092893491 3.22888692733868 0.00152089632949616 -50.4514495631457 174.850688761968 -0.288540182028265 0.773323817492368 TCOF1 other 1 1 1 3.22888692733868 -0.288540182028265 0.000172967409740088 196.801119991705 276.11953174505 0.71273885895699 0.477129573109745 -1725.10591032659 590.659620125592 -2.9206430430436 0.00404044577382885 CDC42 essential 1 1 1 0.71273885895699 -2.9206430430436 0.00142101468714328 168.024610452848 108.933688575274 1.54244855425732 0.125057731756671 -414.368517691934 231.37585995465 -1.79088915227868 0.0753143181792744 OSBPL3 other 1 1 1 1.54244855425732 -1.79088915227868 1.81793493948346e-07 88.3850798086287 25.0983289424627 3.52155237152439 0.000568646438708434 -122.819585926584 48.2757662966934 -2.5441250413667 0.0119666509321968 RAD18 other 0.00177103221804479 1 1 3.52155237152439 -2.5441250413667 2.40846491021492e-11 506.968730007947 92.0538454691884 5.50730637513276 1.54450992777136e-07 -233.161308527573 193.643811189661 -1.20407312320045 0.230457901864664 ATP2B1 other 2.92074539661763e-07 1 0.00177680422090817 5.50730637513276 -1.20407312320045 0.489073738458807 21.6273289978398 18.0526018514249 1.19801728171016 0.232812482031674 24.0205327983311 30.7102886312845 0.782165647699626 0.43535844769532 TRPM5 other 1 1 1 1.19801728171016 0.782165647699626 3.87518661835071e-11 384.919634033401 67.8102543351388 5.67642221382937 6.58933420408171e-08 -508.181665620398 185.688086169153 -2.73674890029006 0.00693009553262757 NCK2 other 4.66533716983242e-07 1 0.000773258368848989 5.67642221382937 -2.73674890029006 0.0293491434869365 298.641175036255 149.163532681958 2.00210580740944 0.0470405577318431 -386.447587941633 410.538582933898 -0.941318560559889 0.348025498822934 MAP4K4 other 1 1 1 2.00210580740944 -0.941318560559889 0.00883534376103116 61.7395915604199 28.9015917573071 2.13620038919865 0.0343191422158459 -236.74822294934 135.262696159594 -1.75028466584759 0.0821555975900985 MGAT4A other 1 1 1 2.13620038919865 -1.75028466584759 0.0280128936803414 1148.70388273067 1089.65569660206 1.05418976499892 0.293447180688755 -6112.18235432126 3094.32926705922 -1.9752850543052 0.0500232552789212 RPL31 essential 1 1 1 1.05418976499892 -1.9752850543052 1.33974125502015e-10 1463.98868099409 307.717472941404 4.75757410523408 4.58812053249119e-06 -1002.92381438328 581.092305141235 -1.72592857539134 0.0864332373428416 WDR1 essential 1.57741135366073e-06 1 0.0479963288903904 4.75757410523408 -1.72592857539134 5.39632354237597e-17 208.899785450888 33.5260609408337 6.23096718160692 4.2325685709478e-09 -180.594585987261 76.4950642848795 -2.3608658633804 0.0194845214752273 SNX13 other 7.44530759141612e-13 1 5.22849195569182e-05 6.23096718160692 -2.3608658633804 0.00848900377326951 33.4098095898513 18.4509131351016 1.81074017015946 0.0721302360710463 -22.1863305745924 29.0633407905989 -0.763378537052731 0.44640554884302 ARHGAP10 other 1 1 1 1.81074017015946 -0.763378537052731 0.0925918836259881 25.7557115034961 67.2461895399218 0.383006259235043 0.702236509942479 -220.989892130019 140.431892520839 -1.57364461991585 0.117595549095245 RPS6KA2 other 1 1 1 0.383006259235043 -1.57364461991585 2.5389044006483e-07 51.5158896695031 10.9448994501987 4.70683992154609 5.6178269911757e-06 -58.9769725126525 33.8522280055578 -1.7421888007776 0.083498120035337 ING3 essential 0.00243963323858295 1 0.0583018085144214 4.70683992154609 -1.7421888007776 0.115236133522978 121.232231920199 58.4094213362993 2.07555954410488 0.0395866189365373 107.545150282189 92.7871220506979 1.15905254851452 0.248217268091293 VASH1 other 1 1 1 2.07555954410488 1.15905254851452 0.325364027014511 22.7195457155995 54.3250134310622 0.418215188191906 0.676387914506246 -113.487224045963 104.684852379888 -1.08408448276865 0.280066741883813 LMCD1 other 1 1 1 0.418215188191906 -1.08408448276865 4.36951637996867e-10 358.109199632015 56.0654319182822 6.38734399039276 2.12327222526928e-09 -414.342477210003 224.178611334118 -1.84826944347721 0.0665864599328314 BUD23 other 5.02275907877399e-06 1 2.6517546821388e-05 6.38734399039276 -1.84826944347721 7.11321816919341e-06 311.856343139526 100.497055791976 3.10313909877174 0.00227625974062152 -351.55767894371 155.555096495278 -2.26002031990242 0.0252129723690966 SEL1L other 0.0595660889488257 1 1 3.10313909877174 -2.26002031990242 5.73305747258475e-07 270.288352150922 48.3851140636541 5.586188177532 1.4728875959108e-07 131.848034872089 167.005267412578 0.789484289416845 0.431386178641101 TRIP13 other 0.00534034303571269 1 0.00169632464421047 5.586188177532 0.789484289416845 1.44790459727337e-07 819.565144695121 163.536392654816 5.01151536603241 1.59300087336237e-06 -138.089682727703 244.389613983512 -0.565039080331048 0.572945096499054 TCF3 other 0.00142198710498218 1 0.0171948514270734 5.01151536603241 -0.565039080331048 0.198897125193711 -82.2226626689495 130.537460220388 -0.629877910372483 0.529701882540711 -744.954389028933 412.408112811849 -1.80635241132805 0.0728032752208244 TRIB2 other 1 1 1 -0.629877910372483 -1.80635241132805 0.0637541567880537 223.924577373212 118.88366062137 1.88356058522108 0.0617134644054738 -75.3564407557565 178.374047908021 -0.422463030017764 0.673339854236991 DAZAP1 other 1 1 1 1.88356058522108 -0.422463030017764 0.000480757475257169 346.162427821277 103.036832050308 3.35959890199518 0.00100597195672582 -71.2369237381572 154.871704003913 -0.459973784083614 0.646248590766221 MBD3 other 1 1 1 3.35959890199518 -0.459973784083614 3.63994070235561e-15 473.207330219189 51.809032821323 9.13368392440693 4.06133991364343e-16 218.368966343274 204.275862692425 1.06899054770886 0.2867798310082 HLTF other 4.89244429803618e-11 1 5.71146232055676e-12 9.13368392440693 1.06899054770886 0.00955140160591334 68.7895089327824 25.942987645606 2.65156464908672 0.00884461263979388 -60.7613805723772 80.1957068936048 -0.757663756901464 0.449802635276598 MYO3B other 1 1 1 2.65156464908672 -0.757663756901464 0.0137220146452847 394.220319957741 196.029898579512 2.01102139425859 0.0460567655656464 -912.071660346744 605.973240384604 -1.50513520987802 0.134324386361432 CYBRD1 other 1 1 1 2.01102139425859 -1.50513520987802 5.03830380049235e-15 306.83351128737 56.1882055647547 5.46081705588118 2.22593634539126e-07 -357.19394447834 116.436219478326 -3.06772193462387 0.00261052114196253 PDCD2 essential 6.75787688760039e-11 1 0.00253400593559341 5.46081705588118 -3.06772193462387 0.240835597785773 17.7368344426903 16.7070954000126 1.06163483346584 0.290119219508174 -18.0535949080288 34.937194844387 -0.516744260334606 0.606100838608207 SLC6A15 other 1 1 1 1.06163483346584 -0.516744260334606 0.000507395723294539 249.405626584371 95.5577029660481 2.61000022858425 0.00995382143925651 -174.869279424912 141.211120994761 -1.23835345398469 0.217481717122343 RDH11 other 1 1 1 2.61000022858425 -1.23835345398469 1.14615131695554e-13 371.338762541907 49.94784634257 7.43453000946347 7.2902149639148e-12 -678.010855797166 353.481634158787 -1.91809358755142 0.0569865156986158 PRKACA other 1.49251824493951e-09 1 9.74847544974687e-08 7.43453000946347 -1.91809358755142 1.62657242554931e-21 738.833415847596 65.671012921127 11.2505256578722 9.61319149855153e-22 338.442673678031 464.621632874041 0.728426422128698 0.467473335980173 ADGRL1 other 2.31688976295243e-17 1 1.38237693749171e-17 11.2505256578722 0.728426422128698 7.50301680034455e-06 1182.57148433687 480.594641216736 2.46064226047739 0.0150034357572913 -1719.73960082514 687.817383153478 -2.500285167177 0.0134849073785051 ACTN1 other 0.0626877053668787 1 1 2.46064226047739 -2.500285167177 6.03813254524961e-07 351.813286093888 68.0129541308336 5.17273937869424 7.1305028191902e-07 83.0893375278698 100.111002926462 0.82997208197888 0.407847705045926 ZFYVE26 other 0.00561425564057309 1 0.00785924020731144 5.17273937869424 0.82997208197888 1.02039721438811e-10 456.360430204819 68.1438714340232 6.69701354797058 3.6380059153043e-10 -95.7339804228007 191.148799161527 -0.500834851397117 0.617193264449395 EPN2 other 1.20804826211408e-06 1 4.65191816389961e-06 6.69701354797058 -0.500834851397117 0.0233358865529347 19.3861325325878 110.243730253095 0.175847937003596 0.860647462586966 -647.024539099745 264.829724884057 -2.44317188858998 0.015704161717457 PTPN18 other 1 1 1 0.175847937003596 -2.44317188858998 6.44134460869117e-05 236.426470588236 53.9253627885 4.38432786285595 2.17778446578911e-05 98.5217086834734 129.389428904428 0.761435532389941 0.447592427062381 LIMS2 other 0.484002633897054 1 0.213858434540491 4.38432786285595 0.761435532389941 1.89664635884119e-06 23.6360055053281 30.9336206493866 0.764087908532519 0.446109959868197 -200.150226229427 52.8446144933643 -3.78752363222481 0.00022573318671306 LNX1 other 0.0168673335939553 1 1 0.764087908532519 -3.78752363222481 0.0134946227287682 48.5875221515488 39.5196268184064 1.22945295953349 0.220753129971403 -521.663003371494 261.911530676072 -1.99175271903809 0.04814356990284 ALDH3A2 other 1 1 1 1.22945295953349 -1.99175271903809 0.140217379035847 445.71669662939 249.271946123446 1.78807404347322 0.0758239716253224 1188.46737565471 931.441218679692 1.27594458117212 0.203987520083733 TFRC essential 1 1 1 1.78807404347322 1.27594458117212 0.0940422079648457 32.4174073951684 203.636467190609 0.159192544647835 0.873735687896054 -1318.22102897929 628.161055201419 -2.09853988569317 0.0375675744765452 SREBF1 other 1 1 1 0.159192544647835 -2.09853988569317 6.36511582767806e-07 425.225262061273 118.236242769448 3.5964037092284 0.000434051121133511 -351.138355444512 196.482597151456 -1.78712191580938 0.0758847107338192 AFF4 og 0.00590428144175417 1 1 3.5964037092284 -1.78712191580938 0.212121265596981 35.7439988741017 33.9606436603332 1.05251240911701 0.294223939786183 -70.4982803662689 73.2931279972122 -0.961867535097566 0.337633837842901 UBE2D1 other 1 1 1 1.05251240911701 -0.961867535097566 2.33989632219244e-10 202.1913627366 37.1563825005692 5.44163207313042 2.06988443999246e-07 -62.466756368623 53.9488085516573 -1.15788945197575 0.248725307333256 MPP5 other 2.72504325682531e-06 1 0.0023607032038114 5.44163207313042 -1.15788945197575 0.000430871167062506 124.048890702895 31.1672142448388 3.98010838339319 0.000105820271505752 49.4776328886702 71.1410630365151 0.695486274407714 0.487798765876777 RHOBTB1 other 1 1 0.965292516675468 3.98010838339319 0.695486274407714 0.00180172930921367 231.983311367885 102.997119875248 2.25232813935834 0.0258034418990018 -746.452723204708 338.573906847396 -2.20469654662771 0.0290511349404616 MARK2 other 1 1 1 2.25232813935834 -2.20469654662771 0.0249420633185652 150.051799496695 55.8122309705252 2.68851104654709 0.00798898865083481 154.817189437815 91.592197745656 1.69028796391293 0.093049953038369 HMMR other 1 1 1 2.68851104654709 1.69028796391293 1.83406263645187e-08 138.48331917991 30.5334373478926 4.53546443533546 1.18449059558673e-05 -71.7785333009828 58.2140622570644 -1.23301021296229 0.219540101062284 CHFR other 0.000192539895574718 1 0.119503256188746 4.53546443533546 -1.23301021296229 0.290683805613275 12.4303839639246 15.110565636706 0.822628633684578 0.411991151752654 80.0737323938276 51.9456117985794 1.54149175688441 0.125249474736943 TRHDE other 1 1 1 0.822628633684578 1.54149175688441 0.0651086268568284 92.359583728347 76.9976856324888 1.19951116672754 0.232171490199153 -128.042919934499 120.869181471891 -1.05935126204421 0.291098550558632 P4HA2 other 1 1 1 1.19951116672754 -1.05935126204421 4.48196012766278e-20 715.110655737705 90.2124691519961 7.92696023576118 4.73007696873895e-13 20.4177917068456 143.081951162333 0.142699980961825 0.886718634732059 NFATC3 other 6.33525064045134e-16 1 6.45560904693492e-09 7.92696023576118 0.142699980961825 9.00970669495803e-08 82.0833715879798 20.7957765149526 3.94711741246882 0.000121870307690636 -86.2056393234224 39.8601130930915 -2.16270433358011 0.0321700508716992 TRNT1 essential 0.000900069698826307 1 1 3.94711741246882 -2.16270433358011 2.08029518557543e-10 969.792010763665 153.946528215442 6.29953804093897 3.22846060451828e-09 -1483.57225263675 807.285532987252 -1.83772926927972 0.0681075371371102 ACADVL other 2.42916068819643e-06 1 4.00296830354221e-05 6.29953804093897 -1.83772926927972 0.91923756618818 16.1629649451431 42.8575412551085 0.377132342915649 0.706601268177958 20.9620551244313 71.6211870884535 0.292679526500207 0.770166271977614 STK10 other 1 1 1 0.377132342915649 0.292679526500207 0.00069000934535516 226.858924270805 68.3145965648196 3.32079724800179 0.00112401254613606 -74.5473160289001 114.163630440604 -0.652986557463102 0.514751388429192 FBXW11 other 1 1 1 3.32079724800179 -0.652986557463102 0.0104411603870453 29.9150721563927 10.066060236154 2.97187493960621 0.00346636741269049 -0.266771174325195 53.517401742642 -0.00498475571755262 0.996029608311384 ACAP1 other 1 1 1 2.97187493960621 -0.00498475571755262 0.0300977433080561 144.48693379791 59.166444246909 2.44204186404962 0.0157290027657692 57.4558094344681 112.044786554642 0.512793242784643 0.608825982115356 CRMP1 other 1 1 1 2.44204186404962 0.512793242784643 0.000574387560864954 133.670949477352 48.5523833745583 2.75312848076159 0.00660824711717961 -67.5115836906995 91.9447078688652 -0.734262854877813 0.463897861427185 EVC other 1 1 1 2.75312848076159 -0.734262854877813 2.44516757101607e-25 297.735452909417 24.5781399060474 12.1138318053174 2.88111485769523e-24 -284.342858700987 130.976970741754 -2.17093781517991 0.0314379354231232 DERL2 other 3.52470905361966e-21 1 4.15802496262576e-20 12.1138318053174 -2.17093781517991 0.864894498700024 -20.4199626478523 37.9140957135879 -0.538584984384424 0.590940942015511 -20.8053261395864 59.0820523071865 -0.352142915269986 0.725206342228725 MRVI1 other 1 1 1 -0.538584984384424 -0.352142915269986 3.06392145873111e-07 66.425889351863 12.5685211931976 5.28509984037057 4.25901779570409e-07 -37.340976420434 73.6800133478045 -0.506799262429107 0.613025280648623 TMEM38A other 0.00291961075802488 1 0.00476754452051116 5.28509984037057 -0.506799262429107 5.42076563069187e-14 311.964121270077 37.4335888076671 8.3338021067908 4.60648251455603e-14 47.719249078526 227.687281786613 0.209582409276809 0.834277989429655 AP1M1 other 7.12505434498139e-10 1 6.35464262883004e-10 8.3338021067908 0.209582409276809 4.35514484210133e-09 62.1213059788101 20.0973864229793 3.09101415832762 0.00236309356493648 -383.699533942222 85.3659638097594 -4.49476016925561 1.35071074604674e-05 PVR other 4.74405927650098e-05 0.19593410082154 1 3.09101415832762 -4.49476016925561 7.04408263710843e-26 344.963477411542 33.0634331358014 10.433383490295 1.3059791216923e-19 -191.431145785597 94.0215870793654 -2.03603397615493 0.0434607065246068 XRCC1 other 1.016320242882e-21 1 1.86781133984433e-15 10.433383490295 -2.03603397615493 1.27361933828181e-05 159.095617529881 79.3980344587911 2.00377274594189 0.0469194054777083 -538.994757810862 182.254902546492 -2.95736767724735 0.00361283681146786 SCARB1 other 0.10408017232439 1 1 2.00377274594189 -2.95736767724735 0.177586999552542 11.6985234361587 25.831593818084 0.452876563426329 0.65131923245095 -50.3082584559033 48.4933767715011 -1.0374253517744 0.301276574954242 CYP2W1 other 1 1 1 0.452876563426329 -1.0374253517744 0.000351630176903572 594.971667874048 145.428279471234 4.09116899434773 7.06965308964801e-05 214.424687486562 600.473732245524 0.357092535396515 0.721538148076249 MCM2 essential 1 1 0.657053558151886 4.09116899434773 0.357092535396515 0.485050115154611 43.3755190537493 36.9879847312566 1.17269214229709 0.242803331781419 54.9457473890022 59.5705477365834 0.922364313854697 0.357839772652098 PANX2 other 1 1 1 1.17269214229709 0.922364313854697 1.41578879649701e-07 140.981222111448 40.7015993684086 3.46377597684462 0.000696873556689689 -118.972026753652 65.5514645025297 -1.81494078975246 0.0715577861074412 SELENOO other 0.00139228670247516 1 1 3.46377597684462 -1.81494078975246 0.681211791408714 -4.037571023465 5.09871654622798 -0.791879875427078 0.429681217152202 -10.6477478506854 19.4658697169303 -0.54699574206153 0.585194502960168 TP63 other 1 1 1 -0.791879875427078 -0.54699574206153 2.2578250865832e-08 138.591132293472 39.5895525537064 3.50069963800328 0.000607214056941918 -98.447676817694 59.880302522784 -1.6440744730746 0.102200739432893 ALPK1 other 0.000235446000028897 1 1 3.50069963800328 -1.6440744730746 1.48956526547312e-09 774.032917892414 115.55992743178 6.69810837627396 3.67341081228215e-10 -734.637088936748 536.341923690867 -1.3697178170994 0.1727560360892 LLGL2 other 1.66637666248478e-05 1 4.69682306458395e-06 6.69810837627396 -1.3697178170994 0.00155666028577659 61.7521643028183 26.5535325248232 2.32557247308208 0.0213461588821583 -80.5479241112543 46.5986059423761 -1.72854793576572 0.0858942758831809 PDE8A other 1 1 1 2.32557247308208 -1.72854793576572 7.38240219370004e-18 138.66964577981 19.3243139360365 7.17591559725262 2.95778878000688e-11 -450.636296906153 74.5870540967286 -6.04174950148511 1.12647895834335e-08 NLE1 essential 1.02763038536305e-13 0.000164713753288965 3.90664742063309e-07 7.17591559725262 -6.04174950148511 5.54334705241373e-08 821.330229476687 140.567353170718 5.84296574524801 4.49728245265603e-08 -25.0613952066135 480.296364526829 -0.0521790233230334 0.958472808459508 SDHA ts 0.000562261691526325 1 0.000531803650026576 5.84296574524801 -0.0521790233230334 2.3258632774113e-17 839.003507797032 88.1014510377803 9.52315197892988 3.41967013789681e-17 -393.066804431635 363.271938057991 -1.0820180786133 0.280935866762455 SMARCE1 other 3.2215532255424e-13 1 4.83883324512398e-13 9.52315197892988 -1.0820180786133 3.06526484185221e-09 7.38336325672286 1.73888763770219 4.24602665326864 3.77400049719111e-05 -29.9853590310773 6.7116745634918 -4.46764197927338 1.53556461442768e-05 FNDC8 other 3.37271090548999e-05 0.222580090861292 0.361247327591133 4.24602665326864 -4.46764197927338 4.72789077367342e-115 287.442290406459 4.22814328819744 67.9831005748629 3.20161511270163e-116 245.675987117514 134.068374346764 1.83246786063118 0.0688258741839789 GSDMB other 6.91548583465211e-111 1 4.68300242534867e-112 67.9831005748629 1.83246786063118 6.49622420000305e-20 442.561100068829 43.6168294288848 10.1465674113338 2.33648590115818e-18 -112.377358409568 172.833023595589 -0.650207674851068 0.516654935363109 KDM5A other 9.17331819282431e-16 1 3.32575403170856e-14 10.1465674113338 -0.650207674851068 0.000498558679002417 29.3780394861 7.41224302816501 3.96344795690987 0.000111895488684826 26.1080786818612 29.2026780118841 0.894030289661668 0.372674145230233 ADAM11 other 1 1 1 3.96344795690987 0.894030289661668 5.38988830341093e-13 205.67165814463 25.7914877212904 7.97440071573895 3.41267939655591e-13 -95.0851716581448 99.1483804678229 -0.959018908927143 0.339072190727724 PPP2R3A other 6.90121298368736e-09 1 4.6637676633333e-09 7.97440071573895 -0.959018908927143 0.00342422557418609 212.544901539622 79.055792346211 2.68854305588158 0.00795125147073866 -101.612848218531 122.108131249466 -0.832154641781695 0.406585628532687 FERMT2 other 1 1 1 2.68854305588158 -0.832154641781695 0.177570436818708 14.0344661525801 8.14906212387159 1.72221857426611 0.0869992473545399 31.2732360023165 25.5401366734438 1.22447410529458 0.222607572736643 DHRS9 other 1 1 1 1.72221857426611 1.22447410529458 8.8410830406546e-05 528.275484911903 120.381096258161 4.38835914717874 2.13410037987068e-05 623.721410950416 507.477956419067 1.22906109134592 0.220960770566507 IGF2BP2 other 0.652825571721935 1 0.209952795371678 4.38835914717874 1.22906109134592 0.00224413226680961 234.452485806759 66.0165108298349 3.55142195277613 0.000512320593285602 188.245901204436 278.298498786714 0.6764172355407 0.499817454126393 MAP3K13 other 1 1 1 3.55142195277613 0.6764172355407 0.356073367473296 142.50661081401 342.246504568367 0.416385876588385 0.677718911023232 -1870.74432341209 1428.53470531624 -1.30955469016621 0.192335547008141 ST6GAL1 other 1 1 1 0.416385876588385 -1.30955469016621 0.000152989374389473 65.6533605800183 28.8813321918884 2.2732109496825 0.0244051875137974 -91.7077256482754 48.4519078957423 -1.89275778046986 0.0602786512566487 FRY other 1 1 1 2.2732109496825 -1.89275778046986 1.15683073597262e-07 459.490602622012 100.097775783068 4.5904177093587 9.04768111453948e-06 -607.240953325254 343.500240738505 -1.76780357422668 0.0790486695271403 PICALM other 0.00114479969631851 1 0.0921777751949282 4.5904177093587 -1.76780357422668 2.04543784276063e-08 253.7476855665 41.110186056134 6.17237988706789 5.70113396472718e-09 -150.308289131214 171.352726231932 -0.877186447140424 0.381751735634017 NSF essential 0.000213952798352762 1 7.00954420963207e-05 6.17237988706789 -0.877186447140424 0.423451434984489 45.5923507622903 38.0418367901766 1.19847921680962 0.232559720957805 1.29401274395864 100.292038360284 0.0129024473439267 0.989722214268391 GLI2 other 1 1 1 1.19847921680962 0.0129024473439267 1.24178491061582e-13 474.111710014829 70.2691127589552 6.74708547468329 2.83160591968856e-10 -347.44317316555 185.254791750331 -1.87548818512507 0.0626063566119087 CLASP1 other 1.61618306116649e-09 1 3.63549884028815e-06 6.74708547468329 -1.87548818512507 1.32980471825371e-05 270.74980471414 100.239508845382 2.70102884414334 0.00778553341486367 -438.975991204902 215.527641972993 -2.03675030815727 0.0436013072160097 MRPS34 essential 0.10849876696232 1 1 2.70102884414334 -2.03675030815727 2.70570018704644e-09 1635.87655991968 258.451993777492 6.32951805095398 2.77137736107457e-09 -1236.90549395186 1818.44675747747 -0.68019890539313 0.497441165567067 NOTCH3 other 2.98411673629352e-05 1 3.44537633528791e-05 6.32951805095398 -0.68019890539313 1.98539459803524e-06 436.67730249957 87.0532012743764 5.01621188086168 1.48034633067704e-06 -215.434486613541 322.605346294417 -0.667795773033875 0.50529700683736 CLNS1A essential 0.0176183916629647 1 0.0160069848736108 5.01621188086168 -0.667795773033875 0.420280952795501 -1.23150623885909 45.6667851317632 -0.0269672199456521 0.978520793053821 -94.9859368572602 87.0100421256459 -1.09166637018859 0.276684727769903 PPP2R2C other 1 1 1 -0.0269672199456521 -1.09166637018859 3.11679501843519e-06 686.40421238909 167.351990744805 4.10155988784016 6.57031409587835e-05 -58.7401533131015 293.49120298129 -0.200142807404167 0.841627907571782 TEAD2 other 0.0270631311450728 1 0.613076008286409 4.10155988784016 -0.200142807404167 0.526278166609568 17.0549243180638 19.4675370414397 0.876069955935351 0.382392782118873 -9.26086305363632 31.9473452283492 -0.289878955119516 0.772309165488127 CDHR2 other 1 1 1 0.876069955935351 -0.289878955119516 0.053548198817987 10.5336924387187 5.59104765009341 1.88402837857101 0.0614834519128981 -5.70577668572325 9.12033003657761 -0.625610768781382 0.532514683868814 SNCB other 1 1 1 1.88402837857101 -0.625610768781382 1.15458514644472e-76 612.396900674772 17.4242766481161 35.1461878758098 5.10699142362575e-76 -110.886639422599 101.041027718239 -1.09744172171146 0.274139412203502 TSG101 essential 1.68811894261682e-72 1 7.46591076219848e-72 35.1461878758098 -1.09744172171146 4.52715178376591e-14 301.882582737526 37.7504913958855 7.996785513908 2.68613361538676e-13 -423.227389990415 212.177959021284 -1.99468121921165 0.0478195855775048 NCBP3 other 5.96225889921971e-10 1 3.67436217248755e-09 7.996785513908 -1.99468121921165 0.326389603008837 30.5824426122545 20.4665892349976 1.49426180694333 0.137114336306902 45.4102556498001 116.570613901994 0.3895514841157 0.697396140655241 ATP2A3 other 1 1 1 1.49426180694333 0.3895514841157 0.278630479138504 -57.0139901672875 171.526332528944 -0.332392055066337 0.740051184582845 -437.704787672814 281.057935969973 -1.55734719306975 0.121467755266413 CA12 other 1 1 1 -0.332392055066337 -1.55734719306975 0.0407733224388601 -247.799968000788 96.9801549046386 -2.55516160233453 0.0116371680814572 -178.510276670112 385.361512582613 -0.463228088019931 0.643890655297147 MGLL other 1 1 1 -2.55516160233453 -0.463228088019931 0.905756027210993 -37.7343824968811 125.050822018283 -0.301752374657434 0.763242726269829 -109.183528180578 248.829648842989 -0.438788258104533 0.661422071601466 NTN4 other 1 1 1 -0.301752374657434 -0.438788258104533 4.48206011214503e-06 70.7563998164789 22.1225313560907 3.19838623698 0.00169052979880684 -148.774278706993 58.3451822116224 -2.54989826182011 0.0117923580077272 BCS1L essential 0.0383081677785035 1 1 3.19838623698 -2.54989826182011 0.996853767888984 -1.61209885247088 52.8723860164369 -0.0304903745401183 0.975715194497223 -8.33547689369706 107.041963765176 -0.0778711133512372 0.938031011401406 NUAK1 other 1 1 1 -0.0304903745401183 -0.0778711133512372 2.03337145457065e-10 214.375410986737 36.7321395057687 5.83618089964704 2.99410252873781e-08 -95.9528168753924 60.9206480954319 -1.57504589782241 0.11727168470417 DPP8 other 2.37579120752034e-06 1 0.000356956903476122 5.83618089964704 -1.57504589782241 5.60417412102605e-13 124.893143448225 19.1072973200135 6.53641074174361 8.49236254446289e-10 -65.3676123979459 31.6896579330622 -2.06274275777989 0.0407949507432269 SLC24A1 other 7.17054078785283e-09 1 1.07470848000178e-05 6.53641074174361 -2.06274275777989 6.5013805033182e-11 560.047643536915 123.433111009502 4.5372561621152 1.14058005510359e-05 -126.762913720862 231.247953174694 -0.548168803142226 0.584369727683429 ZNF532 other 7.75809735460961e-07 1 0.115187179764911 4.5372561621152 -0.548168803142226 0.931673550450873 -2.87217591919022 8.41114315793856 -0.341472718423467 0.733248995307319 3.05669985243124 38.467051874435 0.0794628052705725 0.936775607875906 SCARF1 other 1 1 1 -0.341472718423467 0.0794628052705725 5.836681365792e-17 869.832917917703 184.652519496346 4.71064743817328 5.42333906807661e-06 -824.330411673972 346.950720354541 -2.37592938510578 0.0187186462829307 LMAN1 other 8.05170194411007e-13 1 0.0563701862735883 4.71064743817328 -2.37592938510578 8.6243078805244e-06 747.77830728878 156.167415607903 4.78831198158688 3.87813399349737e-06 130.146433189258 259.005336967317 0.502485526797005 0.616034615647536 HACD3 other 0.0717024957186799 1 0.0407630664056508 4.78831198158688 0.502485526797005 0.162181305969712 19.7040620676462 10.6575168157781 1.84884175256238 0.0664624557789583 13.8925160262826 21.9943463416576 0.631640322948355 0.528589809407258 IPCEF1 other 1 1 1 1.84884175256238 0.631640322948355 2.55809952568198e-19 353.472329917568 34.0060000563818 10.3944106725729 1.38664368360012e-19 -139.039163992509 193.091033178255 -0.720070537217297 0.472552202962917 ZZEF1 other 3.60052508239738e-15 1 1.98290046754818e-15 10.3944106725729 -0.720070537217297 2.07391999476888e-06 3123.50061087092 1706.34610072057 1.83051996869328 0.0691308076701592 -10816.1587796445 3631.09633798878 -2.97875841697868 0.00336996241228479 ENO1 essential 0.0183687093936679 1 1 1.83051996869328 -2.97875841697868 0.149576445425559 19.6236891726488 16.1414792140219 1.21573053574928 0.226010252806662 46.7304023729972 24.159116825065 1.93427610418749 0.0549742017052635 SLC12A1 other 1 1 1 1.21573053574928 1.93427610418749 9.52958198256936e-06 159.329777072932 133.376326726881 1.19458813256416 0.234084597359982 -710.646552856036 225.97874319888 -3.14474955828305 0.00199516664710607 MYDGF other 0.078866820487744 1 1 1.19458813256416 -3.14474955828305 2.08568551263842e-23 134.736368762833 11.5862548445205 11.6289837027497 7.18770187475433e-23 -127.070759852018 116.734183340787 -1.08854798325058 0.278042899653147 ANO8 other 2.99024731946971e-19 1 1.0357478401521e-18 11.6289837027497 -1.08854798325058 2.89971042913633e-17 73.3700283264135 13.1492509862636 5.57978765505803 1.06694787726828e-07 -81.5167048232512 27.4747521544409 -2.9669677951972 0.00349113717764315 TUBE1 essential 4.01232932079594e-13 1 0.00123765953763121 5.57978765505803 -2.9669677951972 1.45033816323308e-07 95.4723639575373 37.8909638880529 2.51966047207472 0.0127595731921783 -250.353634456027 83.9887712517431 -2.9807988701922 0.00333930953574471 ARHGEF10L other 0.00142423207629488 1 1 2.51966047207472 -2.9807988701922 0.656264625753047 10.6695075010303 12.4201368081796 0.859049112406204 0.391657318576567 4.25895432745003 23.3770649315644 0.182185160537389 0.855678580210763 TXK other 1 1 1 0.859049112406204 0.182185160537389 0.12919114790198 -14.5192864934886 15.6248083924403 -0.929245730815713 0.354206645937173 -63.83287311652 31.4804472003371 -2.02769905745927 0.0443040477058171 WSCD2 other 1 1 1 -0.929245730815713 -2.02769905745927 0.111446118857342 17.3525596072932 8.27836798121777 2.09613291492516 0.0376845955815357 18.6824684431977 18.0601339298434 1.03445901983738 0.302522577834623 TACR2 other 1 1 1 2.09613291492516 1.03445901983738 8.24585874319856e-13 48.2884251938134 15.8748096975653 3.04182702745844 0.00276217973637017 -151.190573533382 31.930719089193 -4.73495673902792 4.9080525164743e-06 ACTR6 essential 1.04961535942175e-08 0.0714072560621846 1 3.04182702745844 -4.73495673902792 3.64598315587693e-07 47.9633711553916 9.73000975597905 4.92942683083317 2.08892166147034e-06 -13.5830715874297 16.4166086008724 -0.827398150109268 0.409275302458636 TIPIN other 0.00345383984356222 1 0.0223807066809932 4.92942683083317 -0.827398150109268 0.0142527698409281 83.199678202559 83.0040993597469 1.00235625522499 0.317743934581355 -604.700073223369 255.924257398264 -2.36280874416038 0.0193863307684617 SRI other 1 1 1 1.00235625522499 -2.36280874416038 9.41111814045482e-14 488.072966213188 85.0934449245973 5.7357293108262 4.98810654850426e-08 -339.178658595089 201.858216609066 -1.68028165656476 0.0949298765726032 EIF4G3 other 1.22880969559919e-09 1 0.000588895859116413 5.7357293108262 -1.68028165656476 8.60284092484947e-12 68.748330297511 23.5195648478806 2.92302730693192 0.00398241264457084 -208.81983082188 47.1007664940232 -4.43346990644786 1.74073392438083e-05 NUP37 other 1.0603001439877e-07 0.252162716285808 1 2.92302730693192 -4.43346990644786 0.187638272180482 33.8259404343566 83.3727957447477 0.405719157336613 0.685519504437864 -426.38445680709 271.249165656157 -1.5719290998579 0.118046266534573 SEMA3A other 1 1 1 0.405719157336613 -1.5719290998579 0.10657182419162 119.763130543237 56.218869768777 2.13030128559703 0.0347563328267228 112.250658259423 86.7925909234952 1.29332074391428 0.197862231760366 GTSE1 other 1 1 1 2.13030128559703 1.29332074391428 0.496491813818605 -76.2878647462712 65.7510526830203 -1.16025313106465 0.247776916828597 -125.390272750081 201.956671397593 -0.620877101421544 0.535616541066035 SEMA3C other 1 1 1 -1.16025313106465 -0.620877101421544 0.00154430188231617 81.3732677383592 44.4759773867536 1.82960043869873 0.0692690697542409 -106.416643569845 68.6635168427916 -1.5498280376971 0.123262401646735 TTC38 other 1 1 1 1.82960043869873 -1.5498280376971 2.68520563641541e-07 131.360679893072 39.510994789933 3.32466141618235 0.00110497014700505 -257.662708943927 104.636816936846 -2.46244788867612 0.014894079552215 ACAT1 other 0.00257376960250417 1 1 3.32466141618235 -2.46244788867612 0.000136333719950792 236.769955654103 59.1648307866551 4.00186990321803 9.79072939863721e-05 84.3697339246114 91.3406650941942 0.923682062503114 0.357115853701194 GRAMD4 other 0.981602783645703 1 0.897026627503141 4.00186990321803 0.923682062503114 6.30550007459427e-06 2221.61599223948 436.490558340029 5.08972290417523 1.04530514007247e-06 1878.50845343681 673.868874059335 2.78764686387845 0.00598748410181941 CELSR1 other 0.0530544776276362 1 0.0114136868244513 5.08972290417523 2.78764686387845 3.32662457268383e-05 51.335279664979 21.0467200899869 2.43911067593863 0.015867238287539 -199.986976653968 64.1369125219059 -3.11812603367308 0.00217497017278971 SLC25A40 other 0.259310385440704 1 1 2.43911067593863 -3.11812603367308 3.81909961964124e-17 75.0108347057293 20.4678181184583 3.66481831485903 0.000340731049766065 -157.880384848748 38.9147525793881 -4.05708309532904 7.89719665991285e-05 TIMM21 other 5.27646803449633e-13 1 1 3.66481831485903 -4.05708309532904 5.16728488613254e-10 176.945347478334 35.7216793144955 4.9534442633701 2.12752949004425e-06 -62.4753069556376 63.1557818952268 -0.989225453012076 0.324309556789224 VPS9D1 other 5.91912483706483e-06 1 0.0227810430877875 4.9534442633701 -0.989225453012076 3.05365889623081e-05 119.313950421941 27.5360029677328 4.33301632636208 2.76619852495529e-05 -37.2301511954993 124.739860724445 -0.298462343787141 0.765786612012096 ZNF37A other 0.239101491574872 1 0.268985144566652 4.33301632636208 -0.298462343787141 1.68463502264984e-10 451.891214203895 71.062214035449 6.35909280814797 2.41729641342068e-09 -37.0511615120278 122.882970762844 -0.301515834798086 0.763447287415055 MARK3 other 1.97388685603882e-06 1 3.01219306076351e-05 6.35909280814797 -0.301515834798086 2.20088092872446e-10 792.534296774498 403.523045842682 1.96403725868851 0.0513619965298227 -3837.24764450634 809.90249378007 -4.73791311173361 4.9416786143015e-06 SLC25A3 essential 2.56556689861411e-06 0.0718865988022439 1 1.96403725868851 -4.73791311173361 6.50146069792324e-07 384.570390706571 68.7154249828681 5.59656570271451 1.02045816962254e-07 115.491464474251 373.246645408624 0.309423985171556 0.757431313110884 FNDC3B other 0.00602685406697484 1 0.00118516011819962 5.59656570271451 0.309423985171556 0.618381760825146 276.482585818091 282.706201223685 0.977985571668907 0.329733062237759 146.944642111418 1070.51739078856 0.137265067691405 0.891014358312229 FOSL2 other 1 1 1 0.977985571668907 0.137265067691405 0.00961846266019171 423.981872257961 137.057299576865 3.09346436539253 0.00234479874426657 18.4497483379556 551.622438039362 0.0334463340605428 0.973361416917715 CACNG4 other 1 1 1 3.09346436539253 0.0334463340605428 1.20528681335748e-07 210.574893875075 47.3139874095514 4.45058439172189 1.70344526418348e-05 -89.623321493546 89.7221128394685 -0.998898918641169 0.319519245860186 FRYL other 0.00119118495764119 1 0.169152114733419 4.45058439172189 -0.998898918641169 2.04402958790264e-21 432.415631894681 40.7675331506661 10.6068628262737 6.66160807952811e-20 -406.977721252788 193.082721569436 -2.10778943835444 0.0367346619167993 TMEM131 other 2.91049373021457e-17 1 9.53609196584449e-16 10.6068628262737 -2.10778943835444 0.0202503321825439 923.950664708146 393.277696324369 2.34935943060978 0.0201005692102609 347.067689484681 772.724884116425 0.44914781006637 0.653969004238739 FSCN1 other 1 1 1 2.34935943060978 0.44914781006637 0.0494117234430031 -2545.19332604294 5910.51019151569 -0.43062159501839 0.667357563996175 -24131.704648555 11613.1637911166 -2.07796127589403 0.0394055470825027 ACTB essential 1 1 1 -0.43062159501839 -2.07796127589403 8.16390158946378e-05 37.4434771434997 13.6266913027758 2.74780402017857 0.00672576373702105 -44.5641340412935 34.8440893686419 -1.27895820636366 0.202860900437887 MOCOS other 0.605598219906423 1 1 2.74780402017857 -1.27895820636366 1.68557746895252e-07 79.6612240653113 13.5448662872923 5.88128537969025 2.57727067740794e-08 -22.6008843608163 72.9405886668854 -0.309853330962723 0.757105426606792 PLD1 other 0.00164630351392593 1 0.000308190027604441 5.88128537969025 -0.309853330962723 0.728062643660458 35.307695753449 64.2363544161797 0.549652857394344 0.583343522393921 -19.2671653825482 106.536684085798 -0.180850056934677 0.85672001264034 ATP12A other 1 1 1 0.549652857394344 -0.180850056934677 2.88323015506833e-08 80.8629263370124 16.5676071515925 4.88078487117192 2.64509664504093e-06 -124.439972026518 72.7618836316849 -1.71023571429822 0.0892626306697111 WDR62 other 0.000298443153351123 1 0.0281253126267202 4.88078487117192 -1.71023571429822 3.20729746026799e-12 382.286965921375 47.7561084876555 8.00498570816741 4.00036193731886e-13 227.324789971743 186.561492416625 1.21849791737346 0.225069654346289 DLG1 other 4.00880109558897e-08 1 5.46249422540891e-09 8.00498570816741 1.21849791737346 1.53923371260014e-05 990.950486100455 209.580976017094 4.72824635581251 5.12552765908266e-06 -456.577802574866 855.156406534978 -0.533911456530953 0.594182752133585 RAB7A other 0.124585576697855 1 0.0533669939863686 4.72824635581251 -0.533911456530953 0.00221802677462788 102.732294649733 31.9133819505756 3.21909770668728 0.00156837791228766 -41.6713528557949 103.048456533953 -0.404385997203799 0.68648996534643 BCAP29 other 1 1 1 3.21909770668728 -0.404385997203799 0.270602166032347 -24.1166516539835 19.7570826671811 -1.2206585385222 0.224057162841117 6.38234301392556 36.3734539320232 0.175467059736841 0.860940201557298 SEC31B other 1 1 1 -1.2206585385222 0.175467059736841 1.9575012080355e-17 329.460618518173 52.6937412680553 6.25236718042456 3.74778568121444e-09 -350.260010173679 105.483612277534 -3.32051588499002 0.00112039372178179 SART3 essential 2.71348817457881e-13 1 4.63900911620723e-05 6.25236718042456 -3.32051588499002 0.0537910980407601 -11.0443859069208 5.83676848917687 -1.89220900698742 0.0603158639379836 14.8106621593531 15.6158317605289 0.948438891150774 0.344372996389906 ARHGAP15 other 1 1 1 -1.89220900698742 0.948438891150774 0.193108503194947 7.19460070781618 6.4852225417789 1.10938378158457 0.269005322708837 28.0217000263237 15.8184904460616 1.77145222054361 0.0784763299369389 TUBA3D other 1 1 1 1.10938378158457 1.77145222054361 0.0068350646880684 849.720266025681 307.643117952826 2.76203242146303 0.0064390412218849 109.735440399933 564.594225954441 0.194361605831917 0.84614725605514 PAX2 other 1 1 1 2.76203242146303 0.194361605831917 1.51075992178189e-08 76.6090907792658 19.1857978168309 3.99301042941565 0.000100471079862916 -126.130624390836 42.3349910296884 -2.97934690248037 0.0033543019748506 EXOSC7 essential 0.000159339848950336 1 0.919396730390711 3.99301042941565 -2.97934690248037 4.52433779585899e-07 137.532417582418 38.6777870740636 3.55585021756955 0.000498226579769539 -159.985714285714 75.2162956585744 -2.12700868721227 0.0349818950773921 MKRN2 other 0.0042546872632258 1 1 3.55585021756955 -2.12700868721227 0.202162616507755 57.4175741281605 98.4434266314277 0.583254525902801 0.560575142571581 -345.256441572005 247.768365904917 -1.39346457854309 0.165487189463384 MCM6 essential 1 1 1 0.583254525902801 -1.39346457854309 5.22375012799174e-09 133.011102225819 47.8557583517794 2.77941687284688 0.00613833348619107 -475.971010942606 126.116239879997 -3.77406598385349 0.000230246432666678 REXO2 other 5.66620176383264e-05 1 1 2.77941687284688 -3.77406598385349 3.03061010101544e-08 158.74638020986 45.0595678216195 3.52303379469374 0.000565720812802285 -321.824286300486 119.942019352114 -2.68316548311318 0.00811175313665256 RBM7 other 0.000313243860040956 1 1 3.52303379469374 -2.68316548311318 7.76015276318433e-07 284.409412281386 66.4779875353235 4.27824943001264 3.59011528578469e-05 -304.550677403417 172.735191417112 -1.76310730259941 0.0801964515823689 RBMS2 other 0.0071401165574059 1 0.34465106743533 4.27824943001264 -1.76310730259941 1.24809406841178e-06 710.782419004856 161.856047370337 4.39144802157773 2.28873004579911e-05 -602.239574575053 420.563804066367 -1.4319814704739 0.154512808848305 BAZ2A other 0.0112865146606477 1 0.224295544488313 4.39144802157773 -1.4319814704739 5.01619917863433e-13 1211.4759219118 163.876296639579 7.39262447806134 1.99073173476702e-11 -296.294088524945 376.731320346228 -0.786486475965528 0.433107574783515 PTPN23 essential 6.4282592474199e-09 1 2.63871491443368e-07 7.39262447806134 -0.786486475965528 5.39584765659309e-10 114.464526352097 23.6289565993643 4.84424802554236 3.05466949665633e-06 -126.646687589431 51.860678843234 -2.44205610906603 0.0157284057091159 MLH1 ts 6.17554764297079e-06 1 0.0323458953000938 4.84424802554236 -2.44205610906603 2.37970250157639e-06 263.997247247247 101.255646674807 2.60723481521088 0.0100191732469211 -514.148940607274 202.889566942358 -2.53413198300801 0.0122649491353352 UNG other 0.0209532805263801 1 1 2.60723481521088 -2.53413198300801 0.262874932439898 -24.9291746911095 26.4891173688309 -0.941110054517824 0.348380665578621 -95.0481224016572 57.8508138204034 -1.64298678142596 0.10278383195674 RGS11 other 1 1 1 -0.941110054517824 -1.64298678142596 6.26219601069024e-27 307.962058106258 23.2471681771354 13.2472934234266 3.0404212926769e-26 -473.91484028562 149.023366615743 -3.18013779347509 0.00182339999406639 SLC46A1 other 9.05137811385167e-23 1 4.39796939985714e-22 13.2472934234266 -3.18013779347509 0.575532117534671 11.4903397220612 92.8365582734618 0.123769557335538 0.901664542401117 -294.534443899377 314.119752614006 -0.937650184199987 0.349941591522682 PLXNA2 other 1 1 1 0.123769557335538 -0.937650184199987 6.88866164832877e-18 272.234556419908 26.3357894986149 10.3370569708656 7.68789479964598e-19 245.178992659886 168.822627498656 1.45228750607995 0.148724864966244 SPAG5 other 9.59039474680331e-14 1 1.09652443527351e-14 10.3370569708656 1.45228750607995 0.000509948206455106 176.819366388196 73.0616183630987 2.42014029184853 0.0166864359956077 -208.99115402698 144.388537241389 -1.44742206008769 0.14982463497951 ANKRD13A other 1 1 1 2.42014029184853 -1.44742206008769 3.18699341805162e-09 467.011673907351 89.7656160770078 5.20256746755586 6.26558307607422e-07 -467.218137232763 278.951175536894 -1.67491008537072 0.0960080410985863 TPD52 other 3.50218706709692e-05 1 0.00693537390690656 5.20256746755586 -1.67491008537072 0.000172137154047854 105.902152152152 38.2124827927222 2.77140202395647 0.00626524438920855 -99.1375959292626 76.5677208156801 -1.29477010511929 0.197324966982268 ACACB other 1 1 1 2.77140202395647 -1.29477010511929 1.02602724028172e-08 432.629900824916 92.4462890294308 4.67979737604379 6.85742676897543e-06 -1386.88667469953 372.104050056191 -3.72714748600587 0.000283119191124657 TRAF4 other 0.000109251380545198 1 0.07061092344014 4.67979737604379 -3.72714748600587 0.939737340529463 6.08949323110105 17.360922872094 0.350758613235321 0.726255099505666 9.70172916417084 54.9137135911378 0.17667224687089 0.860001025423755 PAG1 other 1 1 1 0.350758613235321 0.17667224687089 6.41355346888631e-39 91.1763686849849 5.5469262959177 16.4372778401773 1.2710026155815e-35 -53.0145053669858 26.5854491570188 -1.99411734794743 0.0479160896204492 GPATCH1 other 9.33685114000469e-35 1 1.84969010645576e-31 16.4372778401773 -1.99411734794743 3.16182471406817e-12 105.961671983487 17.3008445783006 6.12465313493352 7.17442386456836e-09 -135.378654531807 69.2352961714156 -1.95534159623772 0.0523412503730124 ICAM3 other 3.95354562247083e-08 1 8.7893866764827e-05 6.12465313493352 -1.95534159623772 1.31968179825276e-09 189.459728874135 82.7060031664599 2.29076151210952 0.0233162509131958 -558.700210191364 143.617339785361 -3.89020024341317 0.000147959313113164 NT5C2 other 1.48068297763959e-05 1 1 2.29076151210952 -3.89020024341317 5.72303605783804e-17 403.297649418683 57.1972321618296 7.05099939587327 5.72407362436602e-11 -389.740696021344 171.909006696935 -2.26713366280123 0.0247828260295189 CAMSAP3 other 7.89550054539336e-13 1 7.5082673730809e-07 7.05099939587327 -2.26713366280123 1.5248022964013e-06 526.628324372843 140.774769284884 3.74092834282763 0.000258742151360296 -255.178065425888 311.529755018952 -0.819112978182016 0.413996019077283 RAP1GAP other 0.0136851006102016 1 1 3.74092834282763 -0.819112978182016 4.42737173923127e-32 581.384818495573 46.828670917537 12.4151466848026 6.36748426181449e-25 -238.478351490706 140.704960250319 -1.69488233439991 0.0921320617250673 XAB2 essential 6.42765829101596e-28 1 9.1952840224863e-21 12.4151466848026 -1.69488233439991 6.19557623041446e-14 405.588028608259 82.8401168887373 4.89603399706696 2.46033190236724e-06 -909.545651586343 248.907669715573 -3.65414875574418 0.000354019591133012 STXBP2 other 8.13107424479594e-10 1 0.02622221741543 4.89603399706696 -3.65414875574418 2.97287387095457e-27 365.201885319657 36.6456148499688 9.96577317135582 2.43873993782071e-18 -262.628655300803 101.908571661862 -2.57710073861323 0.0109082358306782 MAP2K7 other 4.29818104262612e-23 1 3.47105855350021e-14 9.96577317135582 -2.57710073861323 5.62198671394323e-07 190.341476858442 34.3251000556503 5.54525628621176 1.22693903632009e-07 126.970291830145 77.2429159778241 1.64377911194597 0.102235705117099 DGKD other 0.00524081601473788 1 0.00141932307721508 5.54525628621176 1.64377911194597 0.0142472852667565 110.319812041781 44.4042376222307 2.48444333129481 0.0140819477737959 -97.0830243156792 137.044912598446 -0.708402978811344 0.479801831686042 CTTNBP2 other 1 1 1 2.48444333129481 -0.708402978811344 0.169233081283054 -29.9338875900317 17.5624742026553 -1.70442314930239 0.0903319203658951 -57.7743046454818 38.6083215397421 -1.49642103933503 0.136603955882187 RARB og 1 1 1 -1.70442314930239 -1.49642103933503 8.99613637790889e-14 529.994720039292 146.290592534762 3.62288996753742 0.0003921950443394 -1115.93271119843 259.34550154786 -4.30288053788544 2.9448227298723e-05 TM9SF3 other 1.1753452177738e-09 0.42523240219356 1 3.62288996753742 -4.30288053788544 4.66745665959996e-06 227.751261352169 107.788455980318 2.11294669063407 0.036249971346657 -493.099725815164 189.017892471263 -2.608746290461 0.0100009485247895 NFKB2 other 0.0397760656531108 1 1 2.11294669063407 -2.608746290461 0.0177402639834864 80.3578764446398 37.228651900797 2.15849546899439 0.0325016416602159 -181.509276734191 137.596151951391 -1.3191450063103 0.189157928294471 UBE2T other 1 1 1 2.15849546899439 -1.3191450063103 0.361988378657646 45.7125688717968 37.8665816492635 1.20720083199498 0.229306960390875 145.63791923973 139.813339967004 1.04165968193093 0.29929131511318 PPP1R12B other 1 1 1 1.20720083199498 1.04165968193093 9.3618255951169e-11 1066.73002366945 155.760946585649 6.84850758198801 1.64678718596634e-10 -210.26484668133 523.002154853496 -0.402034379266047 0.688212559072682 DNAJC10 other 1.10993804255706e-06 1 2.13160133351484e-06 6.84850758198801 -0.402034379266047 4.57976733680456e-10 755.504218121771 116.00577833187 6.51264298197648 1.00396583353195e-09 211.074125263258 237.59602174774 0.888373987538223 0.375734115942661 GTF3C1 essential 5.25986278632004e-06 1 1.26690448533397e-05 6.51264298197648 0.888373987538223 0.287490582919796 -51.6616976593912 68.7640715326722 -0.751289103566895 0.453632717304756 -223.219889790351 140.838414002102 -1.58493612251995 0.115045577769997 IL4R other 1 1 1 -0.751289103566895 -1.58493612251995 3.66223362027063e-11 272.698462826268 50.1030631558429 5.44275031604464 1.99562706966993e-07 -474.229244349745 149.210262684153 -3.17826157409555 0.00178678741379147 USP33 other 4.41189284234003e-07 1 0.00227820786273519 5.44275031604464 -3.17826157409555 1.74931585714983e-05 177.998091727291 54.1371163519703 3.28791231823365 0.0012456473909395 -280.577368455316 180.382418759551 -1.55545851078383 0.121850426551417 SNRPA other 0.140767447024847 1 1 3.28791231823365 -1.55545851078383 0.278174177023562 -11.4978383873651 18.4540288719163 -0.623053018241603 0.534249071334826 86.569358156793 75.1853182769905 1.15141307027341 0.251497347787883 SPAG6 other 1 1 1 -0.623053018241603 1.15141307027341 7.63389690407219e-18 246.724505327245 34.9941442912986 7.05045116329916 5.33279257409983e-11 -240.873059360731 93.1236092819321 -2.58659497004123 0.0106005399222313 EXOSC5 essential 1.06225675420165e-13 1 6.99929025350603e-07 7.05045116329916 -2.58659497004123 1.31278804721565e-09 276.34804837097 49.3775136625131 5.59663757595738 9.67591225819437e-08 -325.938781670345 152.637185312176 -2.13538254786165 0.0343010416609504 DYNC1I2 essential 1.47307946778068e-05 1 0.00112530859562801 5.59663757595738 -2.13538254786165 0.850451277675906 -1.40796738213134 19.6333435874081 -0.0717130719921972 0.942922110096436 41.1113511809742 81.9203518998331 0.501845392842581 0.616483826632514 APBB1IP other 1 1 1 -0.0717130719921972 0.501845392842581 5.11827338539603e-10 503.681314272196 85.1152330651035 5.91764007609469 2.10936614193965e-08 -473.544768469343 286.155894254038 -1.65484890571203 0.100032203540741 LRCH4 other 5.86400581764824e-06 1 0.000253208311678435 5.91764007609469 -1.65484890571203 9.12677270057658e-12 103.484739732706 16.7053370265896 6.19471128107087 5.0290921995017e-09 -65.5111995062778 46.987552486238 -1.39422455607717 0.165245125354676 FAM76B other 1.12405332580301e-07 1 6.19634449900605e-05 6.19471128107087 -1.39422455607717 4.37870859026017e-08 72.9804864464963 29.8065374623972 2.44847247146924 0.0154914569997847 -130.84021329831 43.4469587812723 -3.01149302433358 0.00304850555287238 SIRT6 other 0.000447328869580979 1 1 2.44847247146924 -3.01149302433358 1.89914714052293e-05 125.508845790704 27.3106427985516 4.59560204117055 8.88967971453934e-06 1.71408670887057 104.870693233838 0.0163447637849456 0.986980365920192 POLD3 essential 0.152292609198534 1 0.0906658434085867 4.59560204117055 0.0163447637849456 2.34304560116048e-07 448.122447288846 223.138068195332 2.00827429812006 0.0463623648245129 -1547.40933128979 492.655713742134 -3.14095480500147 0.0020196023247196 CAPZB other 0.00225893026407882 1 1 2.00827429812006 -3.14095480500147 0.567904791075132 11.4003582624272 30.3477383648247 0.37565759020913 0.707675336120605 -75.2557163931405 94.5833868063699 -0.795654701466794 0.427426490534564 GPR137B other 1 1 1 0.37565759020913 -0.795654701466794 0.843597372410098 2.68866541847048 5.28597784562293 0.508641068311861 0.611731745471875 -1.33420029312839 16.4542244842398 -0.0810855774093954 0.935479179933902 NAALAD2 other 1 1 1 0.508641068311861 -0.0810855774093954 7.72824435820562e-14 230.249242401105 45.593882782386 5.05000294666844 1.21969741624307e-06 -137.940562845925 67.1395437889455 -2.05453530157345 0.041592294520605 JADE1 other 1.01162718648912e-09 1 0.0132568912171459 5.05000294666844 -2.05453530157345 8.60744155543054e-21 2706.1431841585 235.609564793176 11.4857102110181 9.14446682072468e-22 2468.90764548325 837.401188451076 2.94829727916907 0.00376212459740635 FGFR1 og 1.22165417996226e-16 1 1.31534010749304e-17 11.4857102110181 2.94829727916907 0.181736602062561 24.8277060774363 13.759000583656 1.80447016674515 0.0731116510529947 15.121388899988 21.4641213194437 0.704496059957039 0.482187919282908 SMC1B other 1 1 1 1.80447016674515 0.704496059957039 0.135806403013631 1790.70435929196 891.945171379209 2.007639501566 0.046430600013805 1503.86738322611 1391.43967996608 1.08079955234766 0.281475930200254 FBLN1 other 1 1 1 2.007639501566 1.08079955234766 0.998561064531039 0.582969088220707 11.236396351998 0.0518822111607916 0.958688084230929 0.161268268263621 56.8372884894127 0.00283736737887595 0.997739690677767 ITGA8 other 1 1 1 0.0518822111607916 0.00283736737887595 0.330842225113564 -16.4801833840353 11.2345414549312 -1.46692087524424 0.144505076382852 -32.0222588799862 43.3329082705116 -0.738982453706612 0.461080179406737 CST7 other 1 1 1 -1.46692087524424 -0.738982453706612 0.000107838692050451 198.679194779339 49.6799812059944 3.99918015177038 9.86511189752731e-05 -34.7567525716183 147.206577467217 -0.236108692761088 0.813664107301266 MAP2 other 0.7883008388888 1 0.903150994218625 3.99918015177038 -0.236108692761088 6.85061559706822e-13 170.986989322241 46.179328169159 3.70267381751204 0.000299799092353883 -256.963404763657 93.2278065007154 -2.75629572773103 0.00657661748820411 PIAS2 other 8.73864525562023e-09 1 1 3.70267381751204 -2.75629572773103 0.924411182013449 -5.87087716739292 15.0192822251326 -0.390889330088549 0.696415795829311 -8.94281364523126 34.591836441088 -0.2585238184871 0.796345643718998 AMPH other 1 1 1 -0.390889330088549 -0.2585238184871 9.31596494781202e-08 189.232388235683 31.7617725750128 5.95786610425368 1.72908359417934e-08 -53.3066590265456 139.811335644275 -0.38127565823543 0.703534651462982 MCCC1 other 0.000929360663193728 1 0.000208268118918901 5.95786610425368 -0.38127565823543 0.110951736961723 113.176508832053 60.2188879137537 1.87941877960527 0.0621141701749003 -221.470943665128 265.075984986376 -0.83549984234336 0.404756390993214 LAMP3 other 1 1 1 1.87941877960527 -0.83549984234336 0.372497971362897 -51.5477834266384 47.9077030477492 -1.07598110840883 0.283629459568895 80.405725570876 137.892830631047 0.583103017052521 0.560682435187731 FAP other 1 1 1 -1.07598110840883 0.583103017052521 0.000574419097739726 110.095975453119 28.5609300047071 3.85477557751004 0.000168932819672253 66.7856857428288 116.141929222087 0.575035098780915 0.566095979180963 NEBL other 1 1 1 3.85477557751004 0.575035098780915 0.014002865418322 89.3521547267088 32.1518743571834 2.77906518712014 0.00613996786668608 191.724502279248 116.786711696021 1.64166367470196 0.10272716351976 ACER3 other 1 1 1 2.77906518712014 1.64166367470196 1.13086383198614e-14 369.210349132429 84.5865949910594 4.36488014645174 2.31377069638634e-05 -532.649869314968 145.193686638349 -3.66854703980141 0.00033488303628117 UBE2K other 1.50676296973833e-10 1 0.226633839711042 4.36488014645174 -3.66854703980141 2.11791653724183e-20 181.282544721092 24.9269794921181 7.27254358188139 1.89923077180765e-11 -72.4990444069703 48.7941789420078 -1.48581338960813 0.139455531081419 PIK3C3 essential 2.99791085846582e-16 1 2.51875984957131e-07 7.27254358188139 -1.48581338960813 2.82904028999013e-12 166.701161073699 23.7840720477813 7.00894114089475 6.93020383479998e-11 43.4479515443361 40.7577621996364 1.06600434370079 0.288079337554545 N4BP2 other 3.54309005918363e-08 1 9.06836380562719e-07 7.00894114089475 1.06600434370079 2.08134688894282e-07 44.5026431609279 9.17955564276016 4.84801714732529 3.00473254503811e-06 -58.2568614862107 42.1359132201352 -1.38259401622205 0.168778168220795 TIGAR other 0.00201807394351895 1 0.0318321365821338 4.84801714732529 -1.38259401622205 7.11457449291892e-24 263.76655942485 25.1259257794935 10.4977847081011 9.34780601004164e-20 -307.929596926823 119.111735342321 -2.58521627648064 0.0106654662303785 TULP3 other 1.02136831420344e-19 1 1.33767104003696e-15 10.4977847081011 -2.58521627648064 0.000157035129000189 145.791430958448 37.582270338063 3.87926087612624 0.000155258635677 59.0292056511784 79.2763651612994 0.744600304656688 0.457655535997991 SYNJ2 other 1 1 1 3.87926087612624 0.744600304656688 0.157930040567442 12.7249316084166 7.42605116712717 1.71355291285172 0.0886361965922112 39.8471288318463 30.9840900296863 1.2860512861171 0.200368008191533 ADCY2 other 1 1 1 1.71355291285172 1.2860512861171 1.27812527478037e-10 478.801586876105 91.4372183387506 5.23639712116211 5.40481056663005e-07 -339.992416525736 148.248189869247 -2.29340012060589 0.0232047603123459 PPP2R5C other 1.5060150112737e-06 1 0.00601014935009262 5.23639712116211 -2.29340012060589 0.92222152659454 2.95744807372702 7.34775449340971 0.402496854839065 0.687876545527677 2.51816906131474 23.7963412855216 0.105821690448139 0.915861541686414 RBFOX1 other 1 1 1 0.402496854839065 0.105821690448139 3.65838849956509e-16 1945.8576344086 303.191218121923 6.41792214979693 2.12903194672706e-09 -1781.16215053764 692.278118774013 -2.57289968039432 0.0111571030222536 GNB1 other 4.996627012706e-12 1 2.65873509507275e-05 6.41792214979693 -2.57289968039432 0.264382693412559 -21.2370072124563 29.3240617175886 -0.724217791415925 0.470030818682106 -133.785219374338 81.6810699594559 -1.63789748886425 0.103484725616863 EDN1 other 1 1 1 -0.724217791415925 -1.63789748886425 4.19772688542396e-13 231.983715855827 30.5696066576644 7.5887046390132 2.94736987506036e-12 -36.9980281234853 118.550351543614 -0.312087038475579 0.755399283240199 MLLT10 og 5.39030109357291e-09 1 3.97158090664384e-08 7.5887046390132 -0.312087038475579 4.09177849599883e-12 38.6670254724043 5.71058570158843 6.77111376888168 2.53208221840139e-10 -37.6911523550832 18.7688021003737 -2.00818103113425 0.0463723848806995 ZCWPW1 other 5.09712847246574e-08 1 3.25676414930787e-06 6.77111376888168 -2.00818103113425 4.95998934436963e-08 554.123916983467 93.9131930982842 5.90038416012064 2.34669854630597e-08 358.700479621607 233.105089533417 1.53879299821201 0.125975801170332 ADCYAP1R1 other 0.000504430916322391 1 0.00028108755187653 5.90038416012064 1.53879299821201 1.00230685075721e-08 578.856691084731 98.3016593893194 5.88857497096966 4.22610907536361e-08 12.2520197403367 279.342220784603 0.043860250362168 0.965094604658843 VDAC3 other 0.000106835887222211 1 0.000500371314523052 5.88857497096966 0.043860250362168 2.94818903778846e-15 800.642255420099 122.565980532332 6.53233672135387 9.05938467862648e-10 25.4070979760501 232.409568829537 0.109320361050561 0.913091647158225 PCM1 other 3.96973653938216e-11 1 1.1450156295316e-05 6.53233672135387 0.109320361050561 0.054441763295071 113.206805050848 51.803146152074 2.18532682780534 0.0303373495247303 232.513319913207 210.08126073039 1.10677801106499 0.270072132275663 TNRC6C other 1 1 1 2.18532682780534 1.10677801106499 0.670391306743712 -0.725698231086309 6.15167319853689 -0.117967617535162 0.906246049847765 7.11729912570931 9.87766273776284 0.720544861133949 0.472274853630492 BRINP1 other 1 1 1 -0.117967617535162 0.720544861133949 0.00302143117439108 12.1140918815449 6.34261278644591 1.9099529309802 0.0579743647769651 -16.8521562887062 10.3002728999258 -1.63608833012838 0.103837067062762 PKD2L2 other 1 1 1 1.9099529309802 -1.63608833012838 2.38866511456713e-07 638.0865993996 181.410759177334 3.51735807894313 0.000611389946540622 -864.565898098731 403.967817128665 -2.14018508762386 0.0343142070025909 SDF4 other 0.00230123997137398 1 1 3.51735807894313 -2.14018508762386 0.115047282780019 12.9663125657958 26.2433211153054 0.494080475135964 0.622029231809308 -84.4441228825724 58.4568969370622 -1.44455363365403 0.150833725305257 TP73 other 1 1 1 0.494080475135964 -1.44455363365403 0.0003187815883807 165.418499195931 59.3587295081173 2.78675942977031 0.0060030912153988 -92.9151800740498 102.614912541886 -0.905474436146144 0.366647126528518 TOLLIP other 1 1 1 2.78675942977031 -0.905474436146144 4.71784399169508e-11 173.334793473467 31.872571414591 5.43836865933309 2.1187976601677e-07 -127.786188446274 73.3771245293565 -1.74149899257976 0.0836326682009623 UBE2D4 other 5.65716673044157e-07 1 0.00241542933259117 5.43836865933309 -1.74149899257976 4.01980473785495e-07 57.6128827050744 14.6053754310331 3.94463551978679 0.000125881493333387 -57.0574574755663 38.6155689453103 -1.47757650693622 0.141767278063584 CLUL1 other 0.00379630359443021 1 1 3.94463551978679 -1.47757650693622 0.000679033496204126 77.9079486093464 20.4857888730305 3.80302409110112 0.000207496953732243 29.1469342501931 80.4520783728963 0.362289388163432 0.717645702726799 RUNX1T1 other 1 1 1 3.80302409110112 0.362289388163432 4.01393102149915e-21 210.846831806472 20.948015161552 10.0652415124016 2.89226837780607e-18 16.926562291596 55.5464689218149 0.304727962373652 0.761025877903871 THOC1 essential 5.70660573326534e-17 1 4.11511944794248e-14 10.0652415124016 0.304727962373652 0.00368914765568718 96.4730030728208 28.4652590820074 3.38914895504325 0.000901673221281323 132.596875152422 108.196777650445 1.22551593524168 0.222354141421333 FKBP7 other 1 1 1 3.38914895504325 1.22551593524168 0.716250823121353 -4.26987009128273 5.33844174161975 -0.799834539355149 0.425115058219032 -7.42151829781616 20.2399380109952 -0.366676928248717 0.714394540377617 OSBPL6 other 1 1 1 -0.799834539355149 -0.366676928248717 0.0595659601059219 120.588737101884 84.6117966423849 1.42520005350503 0.156219182304848 -593.307222945532 351.929347596343 -1.68587026628437 0.0939422209201014 SLC1A3 other 1 1 1 1.42520005350503 -1.68587026628437 4.01808051340432e-11 1847.2230963481 289.105665167554 6.38943929126232 2.04025202859041e-09 -724.531711344213 781.183681416981 -0.927479322187059 0.355187789182526 XRCC5 essential 4.83415266567674e-07 1 2.54949893492658e-05 6.38943929126232 -0.927479322187059 0.972797219423767 -3.84293796300789 22.1827366458438 -0.173240030045072 0.862693244630112 -14.4384412131823 87.7683500827078 -0.164506239431143 0.869551196025122 LXN other 1 1 1 -0.173240030045072 -0.164506239431143 0.331383679879978 -5.78251046239952 6.18008174171639 -0.935668928675618 0.350871556885701 8.58887262830893 14.2938114051907 0.600880505894316 0.548780598493876 SP140 other 1 1 1 -0.935668928675618 0.600880505894316 3.39130994398935e-07 93.1996613739946 32.8380182602937 2.83816339449106 0.00514125561265273 -436.519216697674 110.499556458251 -3.95041600789229 0.000117871823970627 MKNK1 other 0.00322185313990155 1 1 2.83816339449106 -3.95041600789229 0.0232081105542772 400.923894416453 350.513007979651 1.14382030135591 0.254678391924041 -1748.620610277 934.95423908692 -1.8702740061211 0.0635640278754019 TNS1 other 1 1 1 1.14382030135591 -1.8702740061211 7.68163890197558e-07 248.002030084543 71.327958550452 3.47692595056012 0.000656201181603627 -400.072254638088 156.438906552415 -2.55737056372254 0.0114940555506896 SAR1A other 0.00707094860926852 1 1 3.47692595056012 -2.55737056372254 8.36198107557973e-05 55.001155663212 16.9889863642447 3.23745952136193 0.00147879872106724 -100.378169984191 52.2372664881205 -1.92158159744094 0.0565174016616994 CDC14A other 0.619622797700458 1 1 3.23745952136193 -1.92158159744094 0.077489877045028 215.691912400125 117.672209946439 1.83298939059869 0.0688411090596896 -267.250932331452 410.438239272484 -0.651135558921516 0.515982509163341 RAPGEF3 other 1 1 1 1.83298939059869 -0.651135558921516 0.010925627851692 -70.2042065500804 46.9309746238806 -1.49590344357258 0.13671215411365 -390.087918840943 127.988381104718 -3.04783852623136 0.00271061555973288 CEACAM1 other 1 1 1 -1.49590344357258 -3.04783852623136 9.11074318807178e-08 96.3655864408577 28.4377257995484 3.38865305615923 0.000904677673131493 -271.646044441307 81.95637647981 -3.31451994474435 0.00115966812455861 SENP1 other 0.000909616599897086 1 1 3.38865305615923 -3.31451994474435 6.16826155899466e-13 1217.32859591116 215.824201441323 5.6403711343842 7.98154075211276e-08 -1243.02569710119 571.443449864073 -2.17523833267642 0.0311476639715179 CIC og 7.88180462008338e-09 1 0.000931844882809165 5.6403711343842 -2.17523833267642 5.19482778267979e-06 45.1987051581013 11.8715655711977 3.80730788092184 0.000201935755623699 -29.1410456745216 31.4571384105486 -0.926373063379143 0.355692282292934 LIPE other 0.0441144775305168 1 1 3.80730788092184 -0.926373063379143 1.17457581457025e-07 470.559193548391 245.995371251106 1.91287824301399 0.05764405742931 -1210.94541103017 472.31353037098 -2.56385924425886 0.0113214566197413 FDFT1 other 0.00116142056544706 1 1 1.91287824301399 -2.56385924425886 3.8005901378822e-11 445.845039033828 75.3034821343857 5.92064306187299 2.03448174110202e-08 -170.726668827269 198.489295362053 -0.860130358747339 0.39106296318694 PAFAH1B3 other 4.57667064403775e-07 1 0.000244381946741174 5.92064306187299 -0.860130358747339 0.000115272053048346 288.288166951593 81.3050496906092 3.5457596797323 0.000522577471351193 -129.538667446464 177.296394658508 -0.730633398924829 0.46614276909618 KIF22 other 0.8397569064572 1 1 3.5457596797323 -0.730633398924829 3.52159065405087e-07 103.598716297814 22.2506094582454 4.65599454667624 6.88221632486694e-06 -77.1932225328433 64.6059215418535 -1.19483200131795 0.233977734155168 CARMIL1 other 0.00334058089443265 1 0.0708455348481803 4.65599454667624 -1.19483200131795 0.00211759367995042 63.3826423818308 105.24940391027 0.602213789598915 0.54790614690071 -1108.47789337027 342.277889162153 -3.23853198955872 0.00146807043079549 PGM1 other 1 1 1 0.602213789598915 -3.23853198955872 7.6387247885287e-16 529.65737773717 60.938292141705 8.69170039267778 4.78506185054007e-15 -83.0693030352044 190.852939047447 -0.435252941085455 0.663984297191015 DDX1 essential 1.03879018399202e-11 1 6.67372576294824e-11 8.69170039267778 -0.435252941085455 1.53237730752077e-22 1262.73957006184 123.100374962911 10.2578044172675 3.63229913891591e-19 -606.355646478996 500.464562658579 -1.21158557812346 0.227514897115071 DNM2 other 2.19022688563943e-18 1 5.18801286011359e-15 10.2578044172675 -1.21158557812346 2.98630858078408e-10 1396.50174986186 226.974231687954 6.15268852096733 6.08242797081317e-09 443.874009946585 470.160908496477 0.944089570028368 0.346574471464022 EPB41L2 other 3.46143027598683e-06 1 7.47408749053523e-05 6.15268852096733 0.944089570028368 0.828413331060988 19.2960371573853 31.9398633332518 0.604136497268497 0.54662488597154 17.7360727784428 64.2423117483746 0.276080861596509 0.782849036147977 MOXD1 other 1 1 1 0.604136497268497 0.276080861596509 3.38417749968797e-12 227.516546117033 42.4634547414165 5.35793772556912 2.95042518905178e-07 -123.058883510985 85.4089596110159 -1.44081937154417 0.151627094057881 STX7 other 4.22514560836044e-08 1 0.0033330953360718 5.35793772556912 -1.44081937154417 0.000240725684434234 160.323699421965 62.3504979197158 2.5713298974517 0.0112135205130877 -103.028457092041 98.1867617136375 -1.04931108118755 0.295909818744368 RABL2B other 1 1 1 2.5713298974517 -1.04931108118755 1.46451075889296e-20 506.595201903235 56.9184786386426 8.90036441626362 1.38539100119804e-15 -535.515668641004 228.584057227711 -2.34275161240809 0.0204129740713998 KEAP1 other 2.07535819642722e-16 1 1.94051717537809e-11 8.90036441626362 -2.34275161240809 0.168234440365749 7.38005622364517 5.50091258022136 1.3416058001322 0.181764973332411 -3.92709831740056 10.5028965279657 -0.373906217865139 0.70900560848462 DDX43 other 1 1 1 1.3416058001322 -0.373906217865139 0.56971983073574 -5.239852398524 13.6780766761669 -0.383084005345144 0.702182344223739 -28.2278597785978 27.2365013550454 -1.03639815593895 0.301630599172565 PTPRH other 1 1 1 -0.383084005345144 -1.03639815593895 5.68325238678139e-12 358.015445701078 49.0297859980163 7.30199894642743 1.39149160555888e-11 -73.1141998428315 213.123638340632 -0.343060020991076 0.73201813930442 SLC35C2 other 7.04325468293818e-08 1 1.85054468623275e-07 7.30199894642743 -0.343060020991076 6.04436160527773e-20 318.214834644248 31.7059799068113 10.036429581408 2.10715881149758e-18 146.560600363948 76.3289980746642 1.92011691573082 0.0567666319285849 RFX3 other 8.53886963977584e-16 1 3.0003834316914e-14 10.036429581408 1.92011691573082 5.59425652093757e-10 344.434433525109 55.5961051090858 6.19529790529911 4.83948492308818e-09 -226.976451552717 163.156113828296 -1.39116117825401 0.166132402986821 RIF1 other 6.39703233169211e-06 1 5.96514911619849e-05 6.19529790529911 -1.39116117825401 1.80506914933359e-10 205.187080521274 37.1408518223 5.52456582048762 1.37634652531032e-07 -354.941962474713 129.668921458593 -2.73729401372444 0.00692398272863904 RAB21 other 2.1124724254651e-06 1 0.00158747808229293 5.52456582048762 -2.73729401372444 0.887450559535731 -3.69133765740619 10.7697059604168 -0.342751944293876 0.732255522529574 4.60103757222466 28.7749855797472 0.159897128687461 0.873173010761493 SLC4A4 other 1 1 1 -0.342751944293876 0.159897128687461 8.83305500795635e-05 106.236600846625 88.0205473346598 1.20695228629636 0.229376048614091 -684.75764679054 228.012336139858 -3.0031605236066 0.00313795886352098 SMARCA2 other 0.652409442887656 1 1 1.20695228629636 -3.0031605236066 3.44442087811018e-09 75.1941061651402 19.536370183588 3.84892922577342 0.000174267552548728 -83.7129072650937 41.1055697727088 -2.03653440952114 0.0434324731554358 SESN1 other 3.77818526119906e-05 1 1 3.84892922577342 -2.03653440952114 0.568529798686131 -35.0614717115277 41.8612856263014 -0.837563184860683 0.403591095477532 -135.315217226177 138.840761926225 -0.974607279223077 0.331303586021567 COL5A3 other 1 1 1 -0.837563184860683 -0.974607279223077 1.19483426610089e-06 989.038016392705 225.719738954664 4.38170813493345 2.16033912324379e-05 -466.499601915278 481.47195464414 -0.96890295979975 0.334103052350405 SRCAP essential 0.0108287829536724 1 0.212253318858702 4.38170813493345 -0.96890295979975 2.2528084835227e-21 248.393247492139 25.8943809750852 9.59255398810788 3.02809161346634e-17 -16.1977092379096 66.206372991368 -0.244654834664051 0.807062573431607 PUM3 other 3.20709815714291e-17 1 4.28717210634564e-13 9.59255398810788 -0.244654834664051 0.704690208754124 3.94420620759498 6.40428533445095 0.615869843646359 0.538895544779572 -3.23483063956701 11.4885128528442 -0.281570877014442 0.778653039680821 CHRNA3 other 1 1 1 0.615869843646359 -0.281570877014442 3.54759039403005e-11 177.293434569004 23.9994121135535 7.38740739690366 8.30556742914691e-12 35.2529585085843 84.3182751308038 0.418093923931627 0.676449740634822 CNOT4 other 4.27591070192442e-07 1 1.10854408476824e-07 7.38740739690366 0.418093923931627 5.44215398333072e-13 441.301838374607 76.3408447396509 5.78067795659848 3.96900842909827e-08 -217.141243898089 114.973728347007 -1.88861618232233 0.0608114798997045 PSEN1 other 6.96704552945998e-09 1 0.000470645019522473 5.78067795659848 -1.88861618232233 0.0114466269539243 61.366898580611 37.0844745940476 1.65478678752701 0.100130722658267 -100.016535101618 63.742674834033 -1.56906711809681 0.118811983641647 MOK other 1 1 1 1.65478678752701 -1.56906711809681 1.68343685005005e-05 4535.08888029749 1290.11930654874 3.51524766529501 0.000586603703425126 -2992.11970251146 2166.15577877994 -1.38130402800335 0.169310402689184 HSP90AA1 other 0.135701844482535 1 1 3.51524766529501 -1.38130402800335 0.0412769671978637 24.5869225619282 11.7966325916241 2.08423229010162 0.0388574687492159 -41.9409729970988 58.1744437919304 -0.720951852107207 0.472076412509487 RBL1 other 1 1 1 2.08423229010162 -0.720951852107207 0.0277301227513015 19.1734287784564 8.93570668865372 2.14570928148326 0.0335496593685568 -20.6533542484493 25.151925053373 -0.821144075637248 0.412903005735003 IGSF9B other 1 1 1 2.14570928148326 -0.821144075637248 3.32682753670993e-08 52.0954383873646 10.8158025450091 4.81660405416736 3.49994011591002e-06 -11.20431682241 24.5289034680331 -0.456780175151809 0.64848114729667 CROCCP3 other 0.000342729772831857 1 0.0369103684623871 4.81660405416736 -0.456780175151809 2.8297807140886e-08 102.965646408962 19.7650136695056 5.20949027056947 6.24409191658953e-07 -21.149475371308 52.4415820773117 -0.403295906292998 0.68731258879364 NDC80 essential 0.000293080388558157 1 0.00691345857004793 5.20949027056947 -0.403295906292998 0.000115738848219435 46.8991161261878 13.9223104300637 3.36863025442344 0.000954519559562001 -19.8978835130475 20.8272516382983 -0.955377303669687 0.340884221365229 AP4E1 other 0.842694553885704 1 1 3.36863025442344 -0.955377303669687 5.15048476708003e-14 166.936388598326 24.7674569286935 6.74015055639112 3.03414514153102e-10 -230.038753218539 78.6201369668217 -2.92595207911704 0.00395754226195064 RSBN1 other 6.77494766261707e-10 1 3.89098772949939e-06 6.74015055639112 -2.92595207911704 0.000691386726191822 70.6066291841002 35.5664205387037 1.98520481157966 0.0489091825430755 -284.566472883811 112.899635284436 -2.52052605986621 0.0127429290253995 MAGI3 other 1 1 1 1.98520481157966 -2.52052605986621 0.728140440019148 -25.331141586298 35.8997549974366 -0.705607645180496 0.481519294194815 -53.4820806462011 77.919103990298 -0.686379564283239 0.49352641204961 CXCL2 other 1 1 1 -0.705607645180496 -0.686379564283239 0.0103570674039845 41.8109641340002 14.462426813642 2.89100609965134 0.00438457261435784 14.4227025864386 32.9512480854508 0.437698218563284 0.662206607408095 COL4A4 other 1 1 1 2.89100609965134 0.437698218563284 0.029069477432159 177.737065761489 82.085496186046 2.16526760535929 0.031877162053579 -37.2617053730633 136.24117131953 -0.273498128445127 0.784829791509892 TCF7 other 1 1 1 2.16526760535929 -0.273498128445127 0.0129394519987854 4.24562331184905 22.3223472817394 0.190196096237699 0.84940924355546 -104.812880206174 46.435361008675 -2.25717810585328 0.0254218936215889 OSTM1 other 1 1 1 0.190196096237699 -2.25717810585328 0.000126841599449957 627.818643262198 147.774743748393 4.24848405984141 3.71237198004478e-05 -42.6306173267604 629.811169826397 -0.0676879346844725 0.946121856002165 IMPG2 other 0.918206338418242 1 0.355570988248689 4.24848405984141 -0.0676879346844725 4.63931626673972e-07 418.554462435234 84.6240331923934 4.9460472001334 1.96224387793833e-06 -632.615291450778 374.934483446453 -1.68726889464977 0.0935761056567347 PCNP other 0.00435724583772194 1 0.0210588012980342 4.9460472001334 -1.68726889464977 1.93465924535879e-13 256.21898514374 40.5016003001854 6.32614472625089 2.70579924589316e-09 -88.2730278696268 57.8511152666204 -1.52586562009738 0.129135164601179 EXD2 other 2.5057706545887e-09 1 3.36547310204192e-05 6.32614472625089 -1.52586562009738 1.59062553797172e-07 85.4099250523534 26.3340002842205 3.24333273071056 0.0014505856777653 -98.696936576166 38.9152688374309 -2.53620081589244 0.0122088057473811 ARG2 other 0.00155722240167431 1 1 3.24333273071056 -2.53620081589244 0.414891304936121 -40.4994757174394 41.4864253163967 -0.976210300322809 0.330501227382008 -3.0330771050143 60.617989400267 -0.0500359239067889 0.9601590221272 MEF2C other 1 1 1 -0.976210300322809 -0.0500359239067889 0.336671897873819 -51.7765265265265 36.520540091451 -1.41773715276042 0.158287709422101 20.8746037704377 133.44495270865 0.156428574829752 0.875900094936239 PTPRC other 1 1 1 -1.41773715276042 0.156428574829752 0.554725082676072 -6.42719278006527 8.84640285483077 -0.726531776309007 0.468615697769341 22.8925040820673 35.7173539373161 0.640935051410685 0.522517524666902 PKP1 other 1 1 1 -0.726531776309007 0.640935051410685 1.09418460939252e-07 103.007434847636 17.2322981671895 5.9775796500413 1.60389759812408e-08 40.2152265679588 69.7586383161491 0.576490991491286 0.565153212355754 UBA5 other 0.0010852122955955 1 0.000193414011357783 5.9775796500413 0.576490991491286 0.151431994974965 -117.047800453515 61.798273244371 -1.8940302747727 0.0600960137744517 -226.974149659864 213.287003773451 -1.06417243265769 0.288916337912196 STK17B other 1 1 1 -1.8940302747727 -1.06417243265769 1.26573202476626e-05 68.085869080247 36.6609304548793 1.85717787943337 0.065171275021216 -160.652291414367 56.5374009644004 -2.84152240240976 0.00509008193385057 CDC14B other 0.103473593024642 1 1 1.85717787943337 -2.84152240240976 8.35677774632671e-10 78.1160541586072 15.2844775614468 5.11080956771761 9.21212913080096e-07 -29.0671643294649 23.3962317278423 -1.24238658035148 0.215946465146783 ZNF510 other 9.47157189768669e-06 1 0.010087281398227 5.11080956771761 -1.24238658035148 0.62268942493988 69.059882198953 82.7419894431268 0.834641306835167 0.405204250703372 -56.1198734729492 258.816013524266 -0.216833080414043 0.828623567169154 LRP2 other 1 1 1 0.834641306835167 -0.216833080414043 6.49750729689121e-09 101.526254081252 22.5865009716682 4.4949969988093 1.36013638414733e-05 -172.441632185237 76.2341305231956 -2.26200037964319 0.025096557512242 ZNF506 other 7.0062621182378e-05 1 0.136217658872355 4.4949969988093 -2.26200037964319 1.71474915684591e-07 113.80765297302 25.3072505057905 4.49703743782756 1.3596881531272e-05 -145.527822270731 80.6063051957825 -1.80541487315741 0.0729887946591682 JMJD4 other 0.00167393812691298 1 0.136203196591486 4.49703743782756 -1.80541487315741 1.1492358670426e-06 138.274072842176 40.4809804764691 3.41577874880161 0.000815892660081109 -190.427277240165 92.5311258233258 -2.05798076642617 0.0412999240720109 AACS other 0.0104324437291355 1 1 3.41577874880161 -2.05798076642617 1.14457485129254e-09 177.506419400856 60.7381853855644 2.92248473137698 0.00401040471486928 -363.964336661911 91.0429529962896 -3.99772112704587 0.000100021758472838 KIAA0141 other 1.28787562267437e-05 1 1 2.92248473137698 -3.99772112704587 0.614632178354897 22.1814632696618 22.9518891315414 0.966433008739971 0.335352683455807 35.405524185196 70.9673518980164 0.498898764548458 0.618567243009881 CADPS2 other 1 1 1 0.966433008739971 0.498898764548458 0.0537610043438247 4.02237562485124 5.13886950667797 0.782735506247854 0.435033083091005 -23.3112099160064 12.2725235874943 -1.89946344366862 0.0594490951039394 PCDHB4 other 1 1 1 0.782735506247854 -1.89946344366862 0.0871504534133621 33.7181923244325 67.1542774677031 0.502100440893714 0.616374552298874 -184.298167409609 106.55412624508 -1.72962018369625 0.0858711142365556 PCDHA6 other 1 1 1 0.502100440893714 -1.72962018369625 0.0565760846520623 310.062439078075 171.85071555532 1.8042545710452 0.0733258765153103 -135.919632843861 299.827075945085 -0.453326746476878 0.651010352650933 PCDHGA2 other 1 1 1 1.8042545710452 -0.453326746476878 3.2538541314959e-05 8.77016198042861 39.3949807568168 0.222621303829703 0.824129119702337 -522.066206980485 120.691404369663 -4.32562873642152 2.74229723307148e-05 HSPB11 other 0.25386569933931 0.396316796123491 1 0.222621303829703 -4.32562873642152 2.05956499464799e-11 28.6770628375264 12.9210425686588 2.21940781366089 0.0279302845490611 -187.482898647801 37.9207730258416 -4.94406847982868 1.99070692233716e-06 PHLPP1 other 2.50422507699249e-07 0.0290205255138312 1 2.21940781366089 -4.94406847982868 4.42144542331463e-08 111.25330316452 101.728678085929 1.09362772875655 0.275814977389672 -617.930634880776 189.493883552984 -3.26095293048335 0.00136538289386724 ATP8B1 other 0.000451562221083123 1 1 1.09362772875655 -3.26095293048335 0.311349257876493 12.5900959505611 8.22542810347976 1.53063108596559 0.127873020780059 9.07116604325908 24.8327333128114 0.365290680207933 0.715386081650919 IL12RB2 other 1 1 1 1.53063108596559 0.365290680207933 0.849295925183241 -66.9224564142601 181.487258338662 -0.36874465473152 0.712834556676834 -302.293142194783 576.486385321225 -0.524371693576669 0.600788949890153 SMARCD3 other 1 1 1 -0.36874465473152 -0.524371693576669 9.26123429951102e-15 146.002116056331 16.8270989059589 8.67660651858581 6.77035182155363e-15 -74.0388218610511 70.4169163401312 -1.05143516230426 0.294772500764926 WDR70 essential 1.23618955429873e-10 1 9.4371934040636e-11 8.67660651858581 -1.05143516230426 0.0110600614942714 32.2315143186452 16.4896233062491 1.95465437384676 0.0524231296859164 -70.528681620711 48.5116547440199 -1.45385025501331 0.148009636542086 STRADB other 1 1 1 1.95465437384676 -1.45385025501331 0.000918773717219156 296.48241729124 96.5813915783357 3.06976750330594 0.00253795874532359 -331.792073586191 290.955762864647 -1.14035230070539 0.255933201354056 BZW1 other 1 1 1 3.06976750330594 -1.14035230070539 0.0865953660993506 187.338278126865 84.576771924732 2.21500861127195 0.0282085957980527 190.696072911074 234.152767115126 0.814408794995424 0.416652274277154 PGR other 1 1 1 2.21500861127195 0.814408794995424 0.405462564566139 31.1485224101392 33.6064452841547 0.926861563214052 0.355448711149504 153.191600434613 137.703020258579 1.11247814424804 0.267666201204476 C1QTNF3 other 1 1 1 0.926861563214052 1.11247814424804 1.78103190821078e-09 274.57239600129 55.8825774141283 4.91338103406577 2.2795136815254e-06 20.3860045146726 113.161760004152 0.180149235164994 0.857273795465 ME2 other 1.98406954574681e-05 1 0.0243429266050098 4.91338103406577 0.180149235164994 1.1643203402432e-13 239.845805620364 28.2954528719754 8.47647877224521 1.88175235108332e-14 66.9498903088764 118.677583338664 0.564132571842358 0.57349536106251 C5orf22 other 1.51571221892859e-09 1 2.61055503665788e-10 8.47647877224521 0.564132571842358 2.61658463001415e-11 232.062387983039 37.191726648347 6.23962394048604 4.10079359553868e-09 -165.068934144956 91.805046540608 -1.7980376936244 0.0741427444154487 CCNT2 other 3.17025393772515e-07 1 5.06899096344537e-05 6.23962394048604 -1.7980376936244 1.10467649981596e-13 96.0741579068519 14.1388483422092 6.79504833643616 2.38459353972919e-10 -10.2394008371909 27.3391009917984 -0.37453319479169 0.70853662167449 FAM135A other 1.43895160866027e-09 1 3.07040264175531e-06 6.79504833643616 -0.37453319479169 0.122065865415375 40.6358416181009 19.6771991761537 2.065123255313 0.0406098726780667 54.1091189578336 52.0564678794756 1.03943123999712 0.300254813946207 EPB41L3 other 1 1 1 2.065123255313 1.03943123999712 0.129305890712801 29.3896979963919 30.8733444776006 0.951944095908201 0.342588562947035 -141.201896358407 95.5394391010821 -1.47794353501504 0.141426219683332 COBLL1 other 1 1 1 0.951944095908201 -1.47794353501504 0.000317636178017128 30.0388587471755 8.98821171998485 3.34202839040669 0.00104104270243721 -24.3858703687919 27.0217581872419 -0.902453134241482 0.368207510429033 KCNK2 other 1 1 1 3.34202839040669 -0.902453134241482 0.386799011006737 -36.9247997862322 27.3903874224044 -1.34809337366396 0.179595159867617 -14.4991286634859 84.7577530574191 -0.171065514840436 0.864395363062016 SERTAD4 other 1 1 1 -1.34809337366396 -0.171065514840436 0.0114302420164607 56.1634883401565 31.296132977826 1.7945823651743 0.0746690795920992 -150.301413359364 93.5048457404052 -1.60741844092916 0.109997751942994 TRAF5 other 1 1 1 1.7945823651743 -1.60741844092916 0.00369003552532695 131.460620415606 48.1306626807314 2.73132787070964 0.00706472203618696 -43.5499059853733 75.5144719890801 -0.576709402029201 0.56500022433977 MRPL22 other 1 1 1 2.73132787070964 -0.576709402029201 2.09331548627202e-08 223.219675899074 40.1306136064725 5.56232900119602 1.19019479796253e-07 -8.34061350951089 62.9628168054243 -0.132468875007389 0.894790972578764 GEMIN5 essential 0.000218814267780014 1 0.00137800753708102 5.56232900119602 -0.132468875007389 6.86486202097246e-08 1278.73997417649 215.00797533467 5.94740717029718 1.78192252370847e-08 1332.73919024851 929.457371441707 1.43388952651079 0.153644341625561 NFE2L1 other 0.000692595929295912 1 0.000214525652629262 5.94740717029718 1.43388952651079 0.0304759322508654 415.556124478028 164.283642985374 2.52950395381131 0.0124412718571138 -315.825884867765 743.184165657082 -0.424963151076463 0.671464510616891 SEMA5B other 1 1 1 2.52950395381131 -0.424963151076463 0.00109439307435894 945.201986241426 254.32781058669 3.71647121115465 0.000283389913735057 -33.371309722946 1045.91033304467 -0.0319064729246925 0.974588494349217 ITGB5 other 1 1 1 3.71647121115465 -0.0319064729246925 3.22348667926555e-17 555.908464206746 59.8778584292364 9.28404052499169 2.80630435893427e-16 -23.3970399501068 246.250511789173 -0.0950131627346146 0.924440229726941 ERC1 other 4.45711503142048e-13 1 3.94987338519998e-12 9.28404052499169 -0.0950131627346146 0.00613533164710771 80.7440895802651 27.7730297959712 2.90728415925215 0.00419562537527983 -138.492143514317 112.659462574663 -1.22929881209521 0.22087191747483 RNF13 other 1 1 1 2.90728415925215 -1.22929881209521 1.45359109954315e-13 102.003010301104 15.0633796241395 6.77158863722989 2.44537471510592e-10 -28.2956849903451 30.7284619142277 -0.920829850492574 0.358561064729355 PALB2 other 1.88894163385633e-09 1 3.14744179581282e-06 6.77158863722989 -0.920829850492574 5.60796035899349e-11 130.060995836344 22.5599320148066 5.76513243705619 4.36448346841362e-08 -32.2180241560856 43.7464377234346 -0.736471946807834 0.46257124887381 DOPEY1 other 6.70768138539211e-07 1 0.000516492973652068 5.76513243705619 -0.736471946807834 1.80161011771654e-11 261.5361432588 45.2490385056527 5.77992708565791 4.225691539548e-08 -53.8594845756922 89.8444821716263 -0.599474595143268 0.549766918457994 LYRM2 other 2.19526192843761e-07 1 0.000500364135197878 5.77992708565791 -0.599474595143268 1.77789909606311e-07 127.646112405358 28.2400671375257 4.52003572738467 1.24632556103712e-05 -35.9650553290622 54.426374095864 -0.660801971957843 0.509752916358951 BCKDHB other 0.00173362940857114 1 0.125442667718386 4.52003572738467 -0.660801971957843 3.61651897516781e-12 695.567129195326 89.407300915435 7.77975760450728 3.57643244486836e-12 337.830960792967 261.995286414808 1.28945434635832 0.199850202650415 KAT6A other 4.51281320963239e-08 1 4.80994399510345e-08 7.77975760450728 1.28945434635832 0.000627879777946074 46.9697390338703 26.1949566771681 1.79308328747151 0.0749480256778973 -86.0847285695979 39.1602784618313 -2.1982665075659 0.0294422138613592 ZCCHC6 other 1 1 1 1.79308328747151 -2.1982665075659 7.17848164808221e-08 65.384876114234 12.9256940676039 5.05851954813864 1.17383635128581e-06 -90.3015235990041 81.9285874830307 -1.10219797964548 0.272073160058096 ULK2 other 0.00072301667159484 1 0.0127772086837461 5.05851954813864 -1.10219797964548 0.000501900201479848 132.845329962747 34.7556616935613 3.82226444525892 0.000194220424023377 18.6552402493732 152.697243787842 0.122171427503255 0.902928986863128 GRHL2 other 1 1 1 3.82226444525892 0.122171427503255 8.79781746373933e-09 347.132547710918 112.636393802295 3.08188620030062 0.00244012267668248 -301.127316021831 159.827352252758 -1.8840787373216 0.0614514280599258 TNPO1 other 9.41190512270833e-05 1 1 3.08188620030062 -1.8840787373216 0.000161070358494692 1007.63249573193 321.443166017088 3.13471432047296 0.00206039064329594 -535.96987036807 736.737598751561 -0.72749086143601 0.468029866550133 PLOD1 other 1 1 1 3.13471432047296 -0.72749086143601 0.465870508402337 14.9718759166911 12.1587600879876 1.23136535373231 0.22003934300837 4.89164711058955 68.5340479892481 0.0713754294997572 0.943190386567482 P2RX5 other 1 1 1 1.23136535373231 0.0713754294997572 8.26776665641353e-15 96.8662364329715 11.3772270188423 8.51404619706957 1.31970747525449e-14 -86.1463772367257 64.1288599208608 -1.34333243009522 0.181115264644328 ITGAE other 1.10482165829654e-10 1 1.83307368312848e-10 8.51404619706957 -1.34333243009522 9.08844190681509e-15 325.765135901636 39.137997664557 8.32350031531239 5.78931673772273e-14 53.6302647571737 73.7522352268967 0.727167991480959 0.468295467521515 DIS3 essential 1.21367053223609e-10 1 7.97652060123438e-10 8.32350031531239 0.727167991480959 5.41921408120627e-14 119.111233872692 15.2615942667023 7.80463900370939 1.11648299190032e-12 4.07848029082616 28.8088574500174 0.141570358973875 0.887617246775377 PIBF1 other 7.12355690974564e-10 1 1.51473247511117e-08 7.80463900370939 0.141570358973875 1.87976416781867e-08 63.7628778203493 16.5889576236782 3.84369405642086 0.000182732883124278 -70.9078685965659 29.1036134812876 -2.43639397706256 0.0160813896203848 TDRD3 other 0.000197149665920822 1 1 3.84369405642086 -2.43639397706256 1.03139128849971e-20 91.9114875342957 11.4547136855229 8.02390090731457 2.64745852822075e-13 -41.7131098652034 19.7092461875979 -2.11642340189811 0.035948604795579 NUFIP1 other 1.46292540360799e-16 1 3.62225275831163e-09 8.02390090731457 -2.11642340189811 3.56929652848361e-15 260.961086391112 32.7773239659679 7.96163489923896 3.37829101182833e-13 29.6293918275984 55.2072191498684 0.536694154928632 0.592248390496 PDS5B other 4.79784839358767e-11 1 4.61744815496696e-09 7.96163489923896 0.536694154928632 7.41353874458964e-06 162.696110943624 35.9932746169534 4.52018085809263 1.25646761971813e-05 -225.925283891065 151.76779461459 -1.48862467471966 0.138713959343776 OXCT1 other 0.0619697703660248 1 0.126413207219841 4.52018085809263 -1.48862467471966 0.0641088483730451 -42.1059044666853 88.9434106574412 -0.473401055294057 0.636610753433536 299.199529258521 185.590824640308 1.61214612758145 0.109018297621267 EPYC other 1 1 1 -0.473401055294057 1.61214612758145 0.0519025323199681 99.4352338143676 46.7028018347029 2.12910638994 0.0348893337314326 39.8147937859793 69.2730876010837 0.574751251384332 0.566326335929459 CYLD other 1 1 1 2.12910638994 0.574751251384332 1.82403369972378e-09 82.2867070259208 19.1147017835636 4.30489096600386 3.16061981330627e-05 -52.3485370785421 33.8745175638272 -1.5453662765796 0.124564551773579 SLC27A5 other 2.03106152464243e-05 1 0.305726754541115 4.30489096600386 -1.5453662765796 1.31896822423517e-15 95.7374395275293 15.6874870578502 6.10279002458976 9.93004111212472e-09 -51.9740338615914 27.7983697486475 -1.86967920534693 0.0636472480672473 ZNF324 other 1.78707004701623e-11 1 0.000120898250540119 6.10279002458976 -1.86967920534693 0.0539519003985483 20.0777016652145 9.30173188715736 2.15849068848514 0.0324490264804853 4.17130027137266 18.5111344553684 0.22534006661936 0.82201543738147 ZNF671 other 1 1 1 2.15849068848514 0.22534006661936 1.6532356093832e-08 39.6152323781831 7.88706858191094 5.02280815321436 1.40265140965551e-06 -7.53397739530074 15.7307202145203 -0.478934040689787 0.632669319172331 ZNF416 other 0.000173989530468487 1 0.0151879094637498 5.02280815321436 -0.478934040689787 0.0020883774659338 12.6446808717743 14.349815058318 0.881173786587911 0.3796059059974 -67.6689963302933 28.1876931921532 -2.40065747377763 0.017566582193328 ZNF586 other 1 1 1 0.881173786587911 -2.40065747377763 4.9292490798382e-09 110.631970497953 25.2260313526731 4.38562724953681 2.28801563420701e-05 -55.4052846667316 44.704837762971 -1.23935769458543 0.217331984279828 ZNF446 other 5.35464327542824e-05 1 0.224248412308629 4.38562724953681 -1.23935769458543 2.77220895337753e-09 188.741588772254 39.9604017141169 4.723215500248 5.16233219930893e-06 -107.784638806169 79.5245116117267 -1.35536373152998 0.177273456196114 ZNF264 other 3.05636037109873e-05 1 0.0537347158626067 4.723215500248 -1.35536373152998 1.64213423302601e-05 8406.96679239098 2441.64588787379 3.44315563290459 0.000760105175339599 -2654.02605069578 4308.44057534516 -0.616006186991022 0.538897870056319 RPS5 essential 0.132569496632189 1 1 3.44315563290459 -0.616006186991022 0.00262259383755615 729.478058350738 244.665489068491 2.98153229999074 0.00332867228701379 173.403278273527 416.070702825341 0.416763970873282 0.677423958096325 FAT1 other 1 1 1 2.98153229999074 0.416763970873282 4.83323081334034e-14 254.688450158147 43.4386416088993 5.86317713272987 2.673868072874e-08 -208.526451382512 89.8671545073217 -2.32038560167745 0.0216325434268907 YTHDC1 essential 6.36101507343722e-10 1 0.000319473757346986 5.86317713272987 -2.32038560167745 0.168656666817578 -61.0502903970854 42.4503593845922 -1.43815720955343 0.152686609673633 -179.364379890284 102.689971358815 -1.74665916755938 0.0829541361305918 CHMP2B other 1 1 1 -1.43815720955343 -1.74665916755938 3.3730586670491e-07 93.4166239972692 19.663968981269 4.75064947906771 4.6785051359545e-06 -321.578534448427 144.957413932038 -2.21843454381158 0.0280175822303567 SMAP2 other 0.00320520589118953 1 0.0488997356809964 4.75064947906771 -2.21843454381158 1.20521037997475e-27 250.775082170177 19.0571456239969 13.1591103472705 9.94970252574873e-27 -254.375058587704 138.98399712652 -1.83024710647904 0.0692112844069897 PPIE essential 1.74321629359548e-23 1 1.44041843465264e-22 13.1591103472705 -1.83024710647904 3.09919546272913e-20 421.271718723332 40.2650903830171 10.4624555592955 1.31848820275309e-19 -446.648187972918 296.823259801809 -1.50476141347935 0.134474267329591 ZMPSTE24 other 4.38412190157663e-16 1 1.88556997875719e-15 10.4624555592955 -1.50476141347935 5.25522659703298e-07 542.265758335184 132.441562290754 4.0943775424872 7.00494088594418e-05 -1242.81224502744 471.381627496708 -2.63653093911922 0.00928831269678741 STARD7 other 0.00491153477758702 1 0.651599601210528 4.0943775424872 -2.63653093911922 1.62290335661414e-11 219.398014440433 71.2480514849841 3.07935459100482 0.00246778858207525 -465.507945777589 123.34196847942 -3.77412450536055 0.000230718928251798 NOA1 other 1.98091583708322e-07 1 1 3.07935459100482 -3.77412450536055 1.65611566746337e-07 636.672683513839 135.879412930594 4.68557134434374 6.21163716760863e-06 -10.4087798777764 235.229370030135 -0.0442494909391755 0.964764383872658 REST other 0.00161918428807894 1 0.064215905038738 4.68557134434374 -0.0442494909391755 0.12999816079008 18.1811168933237 9.8807989594336 1.84004521982157 0.0676742145025185 5.58812630604755 19.6855478726226 0.283869483450808 0.776889239713085 HAL other 1 1 1 1.84004521982157 0.283869483450808 4.01024985666149e-06 257.743934722352 70.9920996981819 3.63060024732517 0.000383647305192785 -176.559903592278 142.113711023795 -1.24238472361555 0.215971009761459 SSH1 other 0.0344881487672888 1 1 3.63060024732517 -1.24238472361555 0.06036380291924 1551.75603217158 1064.83810765097 1.45726943938431 0.147104856927685 -5660.59490616622 3493.15256986075 -1.62048315753694 0.107201274027663 GSTP1 other 1 1 1 1.45726943938431 -1.62048315753694 7.55334504982557e-11 4184.39352872385 642.587255349096 6.51179041272863 9.79903202455687e-10 -1764.07147834981 1788.80659285642 -0.986172281226273 0.325585485021168 APLP2 other 8.98470393676751e-07 1 1.23702980278006e-05 6.51179041272863 -0.986172281226273 1.75353540277549e-06 29.8221341458091 7.01512464410959 4.25111963917133 3.6981333868704e-05 -41.924223244607 27.6807153575889 -1.51456429875513 0.131959464129899 FAM234B other 0.0156467963989657 1 0.354317058616092 4.25111963917133 -1.51456429875513 3.35256529803928e-25 79.2283170944068 6.17036719572975 12.8401300248772 5.62783084275861e-26 77.3280177453459 37.630315693435 2.05493938385525 0.0416081705797494 SLCO1A2 other 4.8313818510044e-21 1 8.14009453096605e-22 12.8401300248772 2.05493938385525 1.61894325909738e-22 838.92457496405 78.7106620025531 10.6583346349804 4.24801259535087e-20 -443.150006378439 298.128384674966 -1.48644016859241 0.139261607168961 WBP11 essential 2.31379370590198e-18 1 6.08485324158058e-16 10.6583346349804 -1.48644016859241 9.35059796155537e-11 665.284436497089 159.93910977329 4.15961072585757 5.34647893467264e-05 -1572.60201008039 452.407565249856 -3.47607363553232 0.000665700912346621 EIF3I essential 1.10874694702602e-06 1 0.50417296353963 4.15961072585757 -3.47607363553232 0.712672932903424 6.28132761234193 16.1017708560218 0.390101664500636 0.697000398651098 -17.4186264683082 41.3040402055795 -0.421717255300251 0.673819492019832 NKAIN1 other 1 1 1 0.390101664500636 -0.421717255300251 0.482362080435155 -84.8766768469478 73.1757112435499 -1.15990231464172 0.247931475535891 -50.9246014870942 193.003149707611 -0.263853732771938 0.792254770679154 COL16A1 other 1 1 1 -1.15990231464172 -0.263853732771938 8.91498203985199e-14 470.962385442078 81.8047805621924 5.75714991477823 4.67216934400796e-08 -671.274114854618 229.679604523565 -2.92265443528202 0.00400833922796503 TXLNA other 1.16492070314746e-09 1 0.000552110251381421 5.75714991477823 -2.92265443528202 3.44658379297198e-06 300.702101050526 59.2598699700326 5.07429566083404 1.11346288937946e-06 1.20318492579558 201.823438710363 0.00596157182477833 0.995251148091933 NCOA1 other 0.0298163963930006 1 0.0121378589571255 5.07429566083404 0.00596157182477833 9.29912121101156e-05 968.011005290367 227.018406625097 4.26401990781725 3.67145359640732e-05 -327.963105930812 832.41157320021 -0.393991525934649 0.694186749966566 AGBL5 other 0.684787285978891 1 0.351908827215641 4.26401990781725 -0.393991525934649 0.00156786200763989 43.2933424931303 12.6130654216857 3.4324203550626 0.000772064100369892 -15.4485224044929 41.5396977055558 -0.371897805178942 0.710490312386126 EFR3B other 1 1 1 3.4324203550626 -0.371897805178942 7.7698666480043e-10 234.831357583631 35.9279431466134 6.53617594041884 9.1474139955229e-10 -100.410030949697 127.374128898221 -0.788307891235358 0.431752453562759 KIF3C other 8.82190659214408e-06 1 1.15586723247427e-05 6.53617594041884 -0.788307891235358 8.06955734468384e-15 845.112617733029 98.4837586584503 8.58123846251592 1.05708672132476e-14 -229.422353514318 349.151158432657 -0.657086044176963 0.51212586173175 RAB10 other 1.07873842583734e-10 1 1.47009050334634e-10 8.58123846251592 -0.657086044176963 4.78364281825243e-06 457.306390061707 118.217671162107 3.8683420639764 0.0001625102076447 -1013.25093374472 419.113134954652 -2.41760720253818 0.0168143823907056 HADHA other 0.0407327185974194 1 1 3.8683420639764 -2.41760720253818 0.0556421910806257 -63.4111518293154 27.1400906093274 -2.33643847185692 0.0208474398265231 -111.680652940722 100.277089665113 -1.11372052493439 0.267254640440895 MAPRE3 other 1 1 1 -2.33643847185692 -1.11372052493439 7.44705868027873e-17 1324.950474592 135.456190790002 9.7813947584432 1.44872107737522e-17 172.88400310249 509.281309259743 0.33946661689545 0.73476334089385 CAD other 1.02627915672921e-12 1 2.05370699928712e-13 9.7813947584432 0.33946661689545 0.000697328439873543 191.737248429349 465.838335497902 0.411596113541008 0.681204064438682 -2488.64185124055 773.219336806773 -3.21854580295172 0.00156927826381618 CD59 other 1 1 1 0.411596113541008 -3.21854580295172 0.000310911725682601 -518.656521234042 250.683819282812 -2.06896688712451 0.0402885937363261 -1811.81953963854 438.577384301535 -4.13112851800143 6.01499687890577e-05 CD82 other 1 0.864896401217861 1 -2.06896688712451 -4.13112851800143 9.17346742222228e-15 46.2499999999999 23.8632227800427 1.93812882804245 0.0545777183251489 -158.78125 34.4414949562173 -4.61017299631872 8.84099011028297e-06 AK6 essential 1.22484137021512e-10 0.128441904322191 1 1.93812882804245 -4.61017299631872 0.423311473188732 -32.3152330512775 28.6548010353889 -1.12774236370959 0.26121748649183 -45.200117692417 38.5597257683796 -1.17221055885939 0.242958620015808 FCN1 other 1 1 1 -1.12774236370959 -1.17221055885939 2.96620926305695e-15 197.054415805076 21.839755491313 9.02273909996182 8.54020756309153e-16 246.164431349866 129.147409409014 1.90607331944426 0.0585662442798428 MYNN other 3.99311090992727e-11 1 1.19827652317737e-11 9.02273909996182 1.90607331944426 5.84582673806338e-08 633.240425673932 104.323280402329 6.06998191805132 1.0256437265144e-08 518.496751882033 619.89269114644 0.836429851952466 0.404261581350125 MECOM og 0.000592006873763678 1 0.000124738790018681 6.06998191805132 0.836429851952466 7.31682389774711e-16 234.401183512102 74.3280290752793 3.1536041844282 0.00194145623934136 -432.091722187889 104.884092288822 -4.1197069332309 6.19236182996179e-05 SCAMP1 other 9.95673396005427e-12 0.890213936675307 1 3.1536041844282 -4.1197069332309 1.0648317038711e-16 225.761437526888 36.9013225236314 6.11797686606791 7.50704706891168e-09 -174.19076885256 76.4178668634834 -2.27945081434611 0.0240136429603395 PREP other 1.46414359282276e-12 1 9.18712420293412e-05 6.11797686606791 -2.27945081434611 5.74899383860045e-18 120.728452935559 13.1976227198592 9.14774240014394 3.28602284673739e-16 53.276897371385 26.6536412040236 1.99886000428874 0.0473831091825966 HACE1 other 8.01064801470586e-14 1 4.62409134992886e-12 9.14774240014394 1.99886000428874 1.04893540369933e-23 320.761432192197 35.9215213149072 8.92950577956404 1.90926081031645e-15 -257.559020216804 96.2378764842651 -2.67627497224458 0.00831401621306167 SEH1L essential 1.5050125172278e-19 1 2.67143772579477e-11 8.92950577956404 -2.67627497224458 1.40416962021827e-06 49.0534304246234 13.8156549918903 3.55056857263862 0.000514804968851279 -124.467478446539 44.1614716931954 -2.81846310085082 0.0054812335596116 WDR47 other 0.0126403349212048 1 1 3.55056857263862 -2.81846310085082 1.50292319004042e-05 294.578832276405 71.8243841810099 4.10137637287659 6.65104699574769e-05 -106.365952328887 167.775261679765 -0.633978759824014 0.527041373646667 WDFY1 other 0.121796895320875 1 0.6198923898996 4.10137637287659 -0.633978759824014 0.198506799969068 848.86892708727 561.796590516825 1.51098981627203 0.132840267746709 -877.538326407254 1817.46293643758 -0.482836986006066 0.629897154064892 OVGP1 other 1 1 1 1.51098981627203 -0.482836986006066 8.16112657523341e-05 113.295959026785 67.9899278233621 1.66636386673521 0.09771399865748 -741.980771165805 215.746571917405 -3.43913122035542 0.000754541550087644 SLC25A24 other 0.605473980616567 1 1 1.66636386673521 -3.43913122035542 5.12547245158775e-16 140.495927712814 22.2665292556893 6.30973629071157 2.90386034094233e-09 -94.9299983645429 47.1557967014596 -2.01311408151025 0.0458679246096592 MAP3K4 other 6.98806914049474e-12 1 3.60717531551856e-05 6.30973629071157 -2.01311408151025 0.0999498091553384 30.3142365298094 16.8332539691211 1.80085422494176 0.0736700049907456 -35.7757594784069 55.3725844710749 -0.646091559932429 0.51917548681208 PILRA other 1 1 1 1.80085422494176 -0.646091559932429 0.993083257926636 0.169855957129147 1.96389886498329 0.0864891569304879 0.931189926039136 0.607970828193439 5.90406113445736 0.102975022505304 0.918116765934372 ABCB1 other 1 1 1 0.0864891569304879 0.102975022505304 2.70706849109618e-18 277.08307166105 32.1347966479414 8.62252450814252 8.0087817396013e-15 -31.0689445424613 68.3766402592587 -0.454379513597912 0.650203894271226 ZNF213 other 3.78502316425068e-14 1 1.11530294505688e-10 8.62252450814252 -0.454379513597912 0.0128253341117563 356.896936224266 123.986774650075 2.87850810888119 0.00455656525325721 -91.5075577422429 453.524845574043 -0.201769668487332 0.840359664276855 AKR1B1 other 1 1 1 2.87850810888119 -0.201769668487332 8.65115496779393e-08 591.800149018959 109.508738733175 5.40413628962451 2.44854173059015e-07 -69.5740403455031 360.731328229509 -0.192869415270852 0.847317019785906 CPNE3 other 0.000865721077627139 1 0.00278031913508511 5.40413628962451 -0.192869415270852 6.12704968198934e-21 266.135600656779 26.1643512235915 10.1716873612678 5.83553870435717e-19 44.1046539797042 67.1955387707749 0.656362829832485 0.512557700532564 RRN3 essential 8.70163595836126e-17 1 8.32789728498812e-15 10.1716873612678 0.656362829832485 0.000217415016876663 518.97790782736 159.309706974947 3.25766657714696 0.00138202569473009 -1016.41357392506 543.298466779779 -1.87081988276078 0.0632674395660817 CTTN other 1 1 1 3.25766657714696 -1.87081988276078 0.000137907765505274 324.732883817427 75.3263633952304 4.31101236247905 2.89855056335859e-05 137.445307286075 273.273593154105 0.502958612647827 0.615716617763729 WNT11 other 0.992384280575951 1 0.281217375657051 4.31101236247905 0.502958612647827 1.47531746129212e-12 258.913396203105 32.56559840501 7.95051861117567 3.60066440693927e-13 15.2332495984845 138.870263931475 0.10969410705521 0.912793865902134 MTIF2 other 1.86408380720828e-08 1 4.91958777920112e-09 7.95051861117567 0.10969410705521 2.08221951600612e-30 330.618022944818 22.1245951253361 14.9434609343974 1.03880984334821e-30 127.788380019515 77.3641835451116 1.65177701313167 0.10083734783885 DDHD2 other 3.01817718845087e-26 1 1.50814413057293e-26 14.9434609343974 1.65177701313167 0.0423653029947441 8.30277400411935 55.800721625617 0.148793308800288 0.881911394125249 -427.061169785413 181.198621589296 -2.35686765185989 0.0196879673077671 TTC39A other 1 1 1 0.148793308800288 -2.35686765185989 2.72384909982282e-16 287.034948946053 42.754547671473 6.7135536353147 3.43815738655068e-10 -597.902836817272 138.834496742211 -4.30658698556356 2.94046274779464e-05 EPS15 other 3.72677033837759e-12 0.424661630036502 4.3998100075689e-06 6.7135536353147 -4.30658698556356 0.00125389065539584 35.9211000345458 16.1484804218111 2.22442602005007 0.0276032547276897 -106.039040780404 50.1303831281839 -2.11526491846794 0.0360487833073698 ORC1 other 1 1 1 2.22442602005007 -2.11526491846794 0.00147040746119033 -84.6260023162692 137.040909531213 -0.617523647542592 0.537801428795058 -687.690486504649 216.637735321702 -3.17437996424512 0.00181358214473777 MGST2 other 1 1 1 -0.617523647542592 -3.17437996424512 2.08509584577086e-39 1274.84072352417 72.245797476786 17.6458807023869 1.0176274906218e-38 305.759816790707 423.524075791298 0.721941996377503 0.471432052932629 CHERP essential 3.03652508019611e-35 1 1.4817673890944e-34 17.6458807023869 0.721941996377503 2.95708213215916e-08 120.372761045798 26.2667696539659 4.58270136113306 9.3079924928918e-06 -102.161824603068 58.5956463627945 -1.74350537871932 0.0832028957786499 ATG16L1 other 0.000305851004929222 1 0.0947553635776385 4.58270136113306 -1.74350537871932 6.07817050179479e-09 215.4189770708 40.4791479030772 5.32172706763977 3.49356389703094e-07 -84.3609754008866 90.0245432672062 -0.937088624270947 0.350152240633044 USP40 other 6.56442414193838e-05 1 0.00392746453304218 5.32172706763977 -0.937088624270947 2.72338754259942e-15 461.533704537377 63.5745422213512 7.25972517317432 1.72233517380321e-11 -690.910193631612 213.770109416177 -3.23202432519001 0.00149974360773007 POMGNT1 other 3.66976471365272e-11 1 2.28553877563686e-07 7.25972517317432 -3.23202432519001 1.79600111270763e-06 99.9034719009322 22.3956620446282 4.46084030478102 1.55475946500147e-05 -119.057333451459 75.3611470370801 -1.57982379690795 0.116172725085113 RAD54L other 0.0160131459209013 1 0.154869590308796 4.46084030478102 -1.57982379690795 9.05282364832331e-06 208.111645385486 72.3908477402775 2.87483365483086 0.0046071838160039 -743.305196379504 240.57782819095 -3.08966625049725 0.00237321408328086 MAST2 other 0.0751203306337868 1 1 2.87483365483086 -3.08966625049725 5.07775866310594e-10 683.246216992125 181.952946218032 3.75507091912323 0.000248478403162644 -1595.18629763371 451.467821023774 -3.53333332598629 0.000547768326267548 DNAJA1 other 5.81911142791941e-06 1 1 3.75507091912323 -3.53333332598629 0.00720614433683754 320.4454910742 325.534636162284 0.984366809172506 0.326530917398463 -1814.11941749581 802.841905756708 -2.25962223009016 0.0252948532544412 B4GALT1 other 1 1 1 0.984366809172506 -2.25962223009016 1.0557480629611e-09 285.437932713886 69.9879296840459 4.07838800208078 7.35886523941035e-05 -548.420870059303 177.983411885238 -3.08130327568346 0.0024554146456042 CHMP5 other 1.19056709060124e-05 1 0.682829105564886 4.07838800208078 -3.08130327568346 4.42677377432949e-18 274.355395972001 34.9121646048355 7.85844702204462 7.16771272933315e-13 -203.848761423647 88.7836831396389 -2.29601604951479 0.0230694190125334 NFX1 other 6.17667744732193e-14 1 9.75454025334948e-09 7.85844702204462 -2.29601604951479 0.476287759732011 -13.3983107749938 13.084563121221 -1.02397845849847 0.307461722012775 -33.710375658197 33.3212524733759 -1.01167792792699 0.313289302630485 AQP6 other 1 1 1 -1.02397845849847 -1.01167792792699 1.21151775523843e-09 44.492351252846 72.9439330884058 0.609952731763486 0.542792093132614 -445.334354600651 100.675867863831 -4.42344689000333 1.82771164195885e-05 DIMT1 essential 1.36210941221456e-05 0.264670922872062 1 0.609952731763486 -4.42344689000333 3.33424978236503e-19 962.198839499725 186.339410411213 5.16368940620962 7.53028692069713e-07 -1197.86510667584 362.420857890428 -3.30517706306517 0.00118572658470662 EIF2AK1 other 4.68995574387465e-15 1 0.00828482167015098 5.16368940620962 -3.30517706306517 0.202751165783452 -51.165638794102 46.2078392799589 -1.10729347209043 0.269882482796533 -189.031556209498 105.940438040706 -1.78431918637966 0.076328038918082 EPDR1 other 1 1 1 -1.10729347209043 -1.78431918637966 0.499192696086819 7.20720081135904 33.4904976800733 0.21520136488289 0.829904608718254 -58.929753389559 71.382199282655 -0.825552504430586 0.410377823539036 SNX10 other 1 1 1 0.21520136488289 -0.825552504430586 5.71233537804934e-14 383.685523668248 47.6113752102792 8.05869441858531 1.93343991730527e-13 -106.622194153559 237.617500453089 -0.448713558345876 0.65426498359448 SEPHS1 other 7.50543745321903e-10 1 2.64977940666687e-09 8.05869441858531 -0.448713558345876 2.80232283824546e-06 308.468097079183 72.8234690016037 4.23583360293356 4.25974771847866e-05 -39.4495563716099 159.042556545312 -0.248044028142685 0.804488733405994 MRPL28 essential 0.0244670807007211 1 0.405655775230723 4.23583360293356 -0.248044028142685 4.36835999050364e-19 161.49006053175 23.2178004534357 6.95544183246923 8.94140265117265e-11 -288.011150338127 77.5605423029273 -3.71337205473945 0.000283688427595831 ITPKC other 6.13885629465477e-15 1 1.16703187403105e-06 6.95544183246923 -3.71337205473945 0.660325947822548 -2.4356085918854 24.9848653720602 -0.0974833586499557 0.922466887214683 -54.6356021663301 65.784351556337 -0.830525814631474 0.407502741484542 CEACAM6 other 1 1 1 -0.0974833586499557 -0.830525814631474 0.267708037317825 -142.459720808012 121.413586858343 -1.17334249398483 0.242470045368682 -296.377053703398 197.486057007189 -1.50074925893431 0.135467900169556 FAT2 other 1 1 1 -1.17334249398483 -1.50074925893431 8.06731579686142e-07 305.607712611672 70.8921399978673 4.31088287955289 2.88002106340176e-05 -153.3066045945 113.549174663012 -1.35013402826995 0.178941208773055 RBM22 essential 0.00741789687521408 1 0.279477243992507 4.31088287955289 -1.35013402826995 1.32987188241624e-08 304.694601698343 282.245070618523 1.07953914316598 0.282057474848899 -3411.96933548995 668.707552090159 -5.10233408434713 9.87544583628943e-07 TMED2 essential 0.000140806834910231 0.0144102505643135 1 1.07953914316598 -5.10233408434713 0.542007687657606 -7.04433497536947 16.3196359456962 -0.431647801385373 0.666585836670872 -56.3734787018256 50.862651464665 -1.10834722686428 0.269396187091323 ERO1B other 1 1 1 -0.431647801385373 -1.10834722686428 0.00092111283668448 206.163866932534 75.3247898212185 2.73699890065221 0.00692990354989695 -191.73042218365 133.63983380269 -1.43468019023974 0.153405898274165 ZFAND6 other 1 1 1 2.73699890065221 -1.43468019023974 0.0295322519084248 -36.3354112554113 13.718337647801 -2.64867451059099 0.00896375181017916 -2.37783549783549 56.3342986013478 -0.04220937433982 0.966389067178919 LAT2 other 1 1 1 -2.64867451059099 -0.04220937433982 7.04183376857384e-16 115.274713588395 16.909664187155 6.81709064784154 2.04936888241443e-10 -94.09122507623 44.7636450493741 -2.10195628556271 0.0372060102379798 ZW10 essential 9.58745667591328e-12 1 2.64553029030879e-06 6.81709064784154 -2.10195628556271 2.18914363701879e-15 199.644729642687 26.7969112941231 7.45028885797265 6.68085187014561e-12 -64.7246351717307 68.9065686175242 -0.939310090029212 0.349071668706146 ALG9 other 2.95512499561167e-11 1 8.9423202281899e-08 7.45028885797265 -0.939310090029212 0.215475883812371 -13.9547297934547 16.5774163476679 -0.841791597724926 0.401193216520713 -52.0554018232495 29.8073772846966 -1.74639322762474 0.0827110029978983 MYBPC2 other 1 1 1 -0.841791597724926 -1.74639322762474 0.0371770147422207 65.6696629023103 28.8259749016985 2.27814195794783 0.0240934229510619 -29.127803146471 89.7296727042399 -0.324617289561279 0.745911268008513 NOX4 other 1 1 1 2.27814195794783 -0.324617289561279 4.12305352667774e-08 52.7850339625123 15.6685798003438 3.36884610061175 0.000960994315044896 -65.5371756896947 29.7343905790571 -2.20408672965555 0.0290523017383491 ACOX3 other 0.000421994528455467 1 1 3.36884610061175 -2.20408672965555 2.00923209266825e-10 183.983512389149 36.3066002184155 5.06749492605558 1.13410442086087e-06 -232.575844983887 100.98607169057 -2.30304873821134 0.0226057110760108 MTMR2 other 2.34798862349212e-06 1 0.0123537994564375 5.06749492605558 -2.30304873821134 0.000211888823223081 116.736803953872 117.328908499218 0.994953464129861 0.321289879518682 -555.026490939044 207.059766970079 -2.6805134530034 0.00813581444109852 PPP1R15A other 1 1 1 0.994953464129861 -2.6805134530034 0.0584797920559535 140.315288303131 64.5585692083281 2.17345721913908 0.0312444648504767 55.5383690280067 113.931702486495 0.487470719877901 0.626604763077258 HSD17B14 other 1 1 1 2.17345721913908 0.487470719877901 0.609278713756849 5.0164387835835 5.07868150816784 0.987744314250808 0.324868498179207 2.7682256321109 17.2922111364604 0.160085116372083 0.873029399169803 ACHE other 1 1 1 0.987744314250808 0.160085116372083 0.00897905433982702 7543.01517298189 3530.98381102334 2.13623612474049 0.0342101547764328 -3275.54397858321 6231.41129017226 -0.525650422681803 0.599872755541785 FTL other 1 1 1 2.13623612474049 -0.525650422681803 0.0102593537333096 134.078161533523 74.5045709285338 1.79959645243959 0.0739753851847653 -465.254276838303 250.447519809624 -1.85769169202379 0.0652133142045376 SRRT essential 1 1 1 1.79959645243959 -1.85769169202379 0.000107192694847469 123.483196046129 42.6893201091496 2.89260160926439 0.00436350141106961 -68.4635090609556 75.3372786551624 -0.908760049249061 0.364869690684967 BAX og 0.783685792029842 1 1 2.89260160926439 -0.908760049249061 8.05770322211728e-38 183.559802180455 9.85197855581846 18.6317703738856 6.8139991940909e-39 68.5963445315965 62.9990432312174 1.08884740169523 0.27819023969454 NLK other 1.17287928101139e-33 1 9.92322702635458e-35 18.6317703738856 1.08884740169523 2.18989840870228e-34 650.840070088329 38.3901870720108 16.9532924876742 2.38575882142672e-35 36.3545407737702 246.095992375799 0.147725041853812 0.882778555678096 PIGS other 3.18345531673051e-30 1 3.47127908517588e-31 16.9532924876742 0.147725041853812 0.951401841545414 -9.75648055832502 84.9613895077165 -0.114834286666638 0.908726060520081 28.8560454998641 138.85911056326 0.207808082471608 0.83565338248749 ADAMTS2 other 1 1 1 -0.114834286666638 0.207808082471608 8.09681259161751e-10 528.702098786088 76.3186370375235 6.92756211731273 1.07633491090124e-10 295.194597810125 299.258516667909 0.986420039426 0.325464332445338 ATXN7L3 other 9.18340484141258e-06 1 1.40138805399342e-06 6.92756211731273 0.986420039426 5.32917034157882e-10 218.267387477338 32.5953249265718 6.69627892862038 3.54261600355848e-10 284.606965500933 131.857573803219 2.15844230476798 0.0324032298650273 PGS1 essential 6.10190004110775e-06 1 4.53242291495272e-06 6.69627892862038 2.15844230476798 1.63852070561315e-10 600.165363545176 82.8651222969679 7.24267758145983 2.05278689414949e-11 50.7334559296333 346.025887567485 0.14661751548788 0.883628206702524 PSMC5 essential 1.92132937940198e-06 1 2.71994263474807e-07 7.24267758145983 0.14661751548788 8.58926851889175e-06 63.8816200368078 18.9333116409756 3.37403309300391 0.00094144505440009 -60.8378641632078 30.8847396155154 -1.96983574802894 0.050686663001788 UIMC1 other 0.0714283570031038 1 1 3.37403309300391 -1.96983574802894 0.889572062200636 -1.32531848477178 2.86067673311495 -0.463288448299664 0.64383362138532 -1.94240557945948 4.57667923091587 -0.424413746617495 0.671876267210287 CETP other 1 1 1 -0.463288448299664 -0.424413746617495 0.977200090960094 44.8438102119446 1049.22608695811 0.0427398925449466 0.965964243633978 293.97025529865 1626.17931629216 0.180773579120985 0.856782986134609 MMP2 other 1 1 1 0.0427398925449466 0.180773579120985 0.710053645257578 4.59565217391317 12.2828002469786 0.374153456989065 0.708804802113233 -5.0635265700481 19.1501391155452 -0.26441199928087 0.791816002099217 MT3 other 1 1 1 0.374153456989065 -0.26441199928087 0.000521557894049081 -39.625441554271 63.5961867448791 -0.623078891714552 0.534154328993898 -321.122149967887 98.5667481633106 -3.25791563536046 0.00138089230247464 LPCAT2 other 1 1 1 -0.623078891714552 -3.25791563536046 0.00708227134236145 279.606942379058 87.5695289379577 3.19297072589207 0.001707611701929 286.868648098281 136.120171660175 2.10746610586453 0.0366971136813385 GNAO1 other 1 1 1 3.19297072589207 2.10746610586453 9.83153486208353e-11 139.487801932367 49.6804853279174 2.80769805310222 0.00563579592376954 -221.252455716586 77.4569468058761 -2.85645722998988 0.00487596077231603 OGFOD1 other 1.16454530441379e-06 1 1 2.80769805310222 -2.85645722998988 2.91939725326475e-07 597.23254576673 155.716695306073 3.83537901695656 0.000183258132225907 -394.719764939177 294.953290402734 -1.3382449960135 0.182815034944809 SH3BP2 other 0.00278685661796653 1 1 3.83537901695656 -1.3382449960135 1.15570508236845e-10 299.134605082223 59.2587278305693 5.04794172999291 1.31045769425374e-06 -147.370768209076 113.181044188324 -1.30207994868701 0.194939528047283 NOP14 essential 1.36488770227713e-06 1 0.0142145346095703 5.04794172999291 -1.30207994868701 4.55059326985264e-14 1319.8085037267 205.311393996127 6.4283256668726 1.62321966676963e-09 -446.510557470538 388.958445298328 -1.14796468072076 0.252810657025783 ADD1 other 5.99267627706894e-10 1 2.0342188863957e-05 6.4283256668726 -1.14796468072076 2.25412580871659e-10 149.389974096896 23.3315742947819 6.40291015983035 1.72684437110482e-09 -6.14365841124173 38.1989421258981 -0.160833208181345 0.872434199271728 L2HGDH other 2.62650739231656e-06 1 2.1630452592459e-05 6.40291015983035 -0.160833208181345 0.00640084244714866 92.0119869355867 34.2457611107077 2.68681389904391 0.00799067382968826 -24.7155908728689 52.6154019932479 -0.469740607057239 0.639192127664302 TXNDC16 other 1 1 1 2.68681389904391 -0.469740607057239 0.373373883154903 -142.76189433988 129.874155679811 -1.09923251160024 0.27334940716004 64.7393234340071 199.539466725133 0.32444370277478 0.746034004331997 NID2 other 1 1 1 -1.09923251160024 0.32444370277478 6.68808897982612e-49 225.512315990764 10.0488065095394 22.4417014873044 2.45514954739017e-49 -137.239486320662 128.361066884127 -1.06916754162342 0.286746688448008 KLHL42 other 9.75591539487236e-45 1 3.58132664477804e-45 22.4417014873044 -1.06916754162342 3.56290158425787e-09 7219.01489235006 1133.93651413396 6.36633074459511 2.32960570699562e-09 -314.331420465156 4601.28511274636 -0.068313832497448 0.945628646950306 GNAS other 3.90351497571292e-05 1 2.90455239548213e-05 6.36633074459511 -0.068313832497448 2.11853117565726e-25 758.707885044804 58.2778155836717 13.0188113168981 7.84397745125395e-26 -221.157004900966 361.73955762119 -0.611370805988985 0.541952696895248 DNM1L essential 3.0540745428275e-21 1 1.13431757922583e-21 13.0188113168981 -0.611370805988985 0.79388131122612 -1.11161222588612 1.70115452424258 -0.653445768767571 0.514489734990073 -5.71002706019787 21.6616908298543 -0.263600247323642 0.792457117677337 PTHLH other 1 1 1 -0.653445768767571 -0.263600247323642 0.141867486455551 -0.876396769878779 2.74214440204156 -0.319602705541799 0.749729538482372 -21.4834090739156 10.9210689907784 -1.96715258296196 0.0510742533415131 PHACTR3 other 1 1 1 -0.319602705541799 -1.96715258296196 3.40918912422857e-06 107.949671024524 23.6986669138765 4.55509465645577 1.09663777623111e-05 -306.322609587285 176.270183340288 -1.73780161671434 0.0843543165772723 ERGIC2 other 0.0295099410593225 1 0.110957810199064 4.55509465645577 -1.73780161671434 0.193098127015733 -100.9254585106 55.3620781989578 -1.82300704370054 0.07024165939273 -112.665146044117 227.721447583042 -0.494749823698676 0.621481821348169 TFAP2C other 1 1 1 -1.82300704370054 -0.494749823698676 0.0236745935569434 83.721441748514 38.066814522476 2.19932880643537 0.0293453449122679 -154.025035445979 156.848723025298 -0.981997382415007 0.327641364891179 AURKA essential 1 1 1 2.19932880643537 -0.981997382415007 0.580744709611773 -3.13494911256077 3.00710176221042 -1.04251513931353 0.298806720800582 -4.44605540068634 12.3903215261509 -0.358832931922109 0.720211548454392 CASS4 other 1 1 1 -1.04251513931353 -0.358832931922109 0.000273985495506254 63.966403846987 15.3579505015906 4.16503516145347 5.26815637413498e-05 56.8055711995841 56.9170517469195 0.998041350633707 0.319888283862531 AAMDC other 1 1 0.497208598590859 4.16503516145347 0.998041350633707 0.0297076219910863 97.5015228102629 43.018029146292 2.266526959631 0.0247936329029928 19.7558365534704 81.9777972756047 0.240990087682551 0.809879241285426 RFX2 other 1 1 1 2.266526959631 0.240990087682551 2.38993872621628e-10 143.56879509958 20.1020395664229 7.14200141857185 3.29237519409903e-11 35.2240723517525 82.8545757640526 0.425131286074786 0.67132681101439 METTL2A other 2.78188867731575e-06 1 4.34461830613308e-07 7.14200141857185 0.425131286074786 0.117706278353551 -33.6426032591638 22.7765703326604 -1.47707063740506 0.14165980222499 -81.9500882230685 39.7256272958588 -2.06290230769022 0.0407689819550692 SULT2B1 other 1 1 1 -1.47707063740506 -2.06290230769022 2.31646899015234e-07 57.4601288496409 19.0945988687675 3.00923466601996 0.00304917201855076 -236.1839793015 59.9701952461994 -3.9383560172162 0.000122789216634573 ALG6 other 0.00223423434100193 1 1 3.00923466601996 -3.9383560172162 7.16263524240802e-14 451.171323283868 85.6987688533849 5.26461849242829 4.58460965772841e-07 -478.783175834412 176.973117880778 -2.70540058042576 0.00758098295044428 CNOT3 other 9.38305216755451e-10 1 0.00512100898768264 5.26461849242829 -2.70540058042576 0.0693914241509686 2.47130111101639 2.92713381230992 0.844273364143264 0.399801296254599 -8.00554087460575 6.1030609969366 -1.31172552242622 0.191527633520249 GP6 other 1 1 1 0.844273364143264 -1.31172552242622 1.12300474327749e-12 191.282468168463 29.5049199198566 6.48307023669402 1.13842755703153e-09 -145.984792093313 78.701149637736 -1.85492578908041 0.0655064410980229 PTPN4 other 1.42363311305287e-08 1 1.43328029430269e-05 6.48307023669402 -1.85492578908041 2.99608957205342e-12 285.067581608797 53.5187992236353 5.3264943486046 3.46566052019355e-07 -524.600672496897 147.917866438905 -3.54656732906281 0.000516502568991898 DDX18 essential 3.74930649046765e-08 1 0.00389782838706168 5.3264943486046 -3.54656732906281 0.000371257558885932 164.342825061097 90.6329399030701 1.81327920331017 0.0718013087486932 -311.695499012909 135.632237801409 -2.29809302025444 0.0229477619206454 GNA11 other 1 1 1 1.81327920331017 -2.29809302025444 2.93835473552165e-08 275.435521523952 60.9759442761057 4.51711777150592 1.25615840677379e-05 -89.3623587636566 134.709215991329 -0.663372272684065 0.508103638445511 ASAP3 other 0.00030394341384236 1 0.126394658889579 4.51711777150592 -0.663372272684065 0.926220873441113 -5.65028008499187 15.6222944688082 -0.361680551872412 0.718089763680916 -0.685306805744721 30.2778547021199 -0.022633928740557 0.981971771368093 SLC15A1 other 1 1 1 -0.361680551872412 -0.022633928740557 0.0649154328739968 86.838403837486 81.3964080930796 1.06685793478974 0.287716528755999 -225.37806644775 157.755867579978 -1.42865092693614 0.155142908348628 DOCK9 other 1 1 1 1.06685793478974 -1.42865092693614 2.70490461184639e-09 353.710837999319 56.2542386746893 6.28771886941323 3.20800020268356e-09 23.9440199082063 102.520487147415 0.233553512809366 0.815643814646716 ANKRD10 other 2.98350978686656e-05 1 3.97824105134788e-05 6.28771886941323 0.233553512809366 2.44211018897699e-06 96.2353942956797 21.4263241510506 4.49145609938703 1.40907548003616e-05 -26.2148453971205 40.0096817712038 -0.655212544479375 0.51334121626164 TGDS other 0.0214612643407298 1 0.140865275739215 4.49145609938703 -0.655212544479375 0.00821964312819706 26.8999207816214 17.344326322077 1.55093488683855 0.12319117465725 -73.5021442752495 39.5248343995779 -1.85964458527964 0.0650496520835739 DOCK3 other 1 1 1 1.55093488683855 -1.85964458527964 3.18395891916406e-10 50.4081002542681 8.42073049785876 5.98619089722512 1.78197389906436e-08 -19.6191064293497 18.5760523816886 -1.05615046869104 0.292758350932323 C3orf18 other 3.68606924071623e-06 1 0.000214525652629262 5.98619089722512 -1.05615046869104 3.38859526879753e-11 286.783783783781 100.385829668482 2.85681539646449 0.00488703099191597 -469.555221888559 155.967508822219 -3.01059640840827 0.00306012712346114 COQ9 other 4.08596817511607e-07 1 1 2.85681539646449 -3.01059640840827 0.897416936586167 -2.13186813186812 5.51351281731043 -0.386662406075275 0.69952971052133 -4.44285714285714 10.7220718028683 -0.414365546560565 0.679171998582629 TMEM40 other 1 1 1 -0.386662406075275 -0.414365546560565 0.000658264715076242 79.0130306851617 31.5881756510548 2.50134833863136 0.0135586024035026 -130.516762235599 70.93554865146 -1.83993448583714 0.0679580604871571 KIF9 other 1 1 1 2.50134833863136 -1.83993448583714 0.00277367186479065 42.7090710124462 13.5133108281777 3.16051865863915 0.00190326288474307 10.6558673017632 37.1029206156926 0.287197533912095 0.774354813112076 ARHGAP28 other 1 1 1 3.16051865863915 0.287197533912095 1.65145122721207e-11 209.894304684127 33.5043173042394 6.26469427143255 3.56312276623529e-09 -221.034761954328 115.605547952831 -1.91197365410623 0.0577364589794129 CRLS1 essential 2.01510078744417e-07 1 4.41328385825903e-05 6.26469427143255 -1.91197365410623 1.3266595360741e-13 746.709776120539 94.6029112063607 7.89309511302157 6.06367695034096e-13 57.4057318954321 186.180501594339 0.30833374818439 0.758261938798147 PPP1R13B other 1.72532072666437e-09 1 8.2641853156197e-09 7.89309511302157 0.30833374818439 3.49461462153294e-18 805.920729004303 82.0960860798578 9.81679843080894 7.08718104284307e-18 177.402811342608 305.993613033668 0.579759850487757 0.562946355037349 ATRN other 4.88127770335721e-14 1 1.00623796446286e-13 9.81679843080894 0.579759850487757 0.0120988020198067 40.9502093775775 13.9398091235729 2.93764491425701 0.00381562355252268 26.4614079055898 50.7039417361272 0.521880686186094 0.602503215455695 SMOX other 1 1 1 2.93764491425701 0.521880686186094 0.756174679698841 18.7963656591879 49.6592189561562 0.378507073898666 0.705600020451355 -85.5972000741702 184.334366270074 -0.464358338633173 0.643078019553484 SIGLEC1 other 1 1 1 0.378507073898666 -0.464358338633173 6.60942618678181e-10 288.120068339293 52.8445457204352 5.45221960774422 1.93829852537531e-07 -371.471034897332 185.173442114834 -2.00607079857038 0.0465995883664889 NSFL1C other 7.52794043998457e-06 1 0.00221469989509382 5.45221960774422 -2.00607079857038 0.0183862473633887 215.923600605143 89.0393479754772 2.42503573436557 0.0165031965701789 -181.46293494705 330.62120122094 -0.548854502605797 0.583926827687912 SLC4A11 other 1 1 1 2.42503573436557 -0.548854502605797 3.58897087280381e-09 120.438731403297 20.3846922142777 5.90829285707537 2.23277844431771e-08 -55.6780400942045 75.8947417869307 -0.733621839712121 0.464324322962987 C20orf194 other 3.93064089989474e-05 1 0.000267732463258137 5.90829285707537 -0.733621839712121 3.6591311541434e-07 49.4811379872163 11.0824605496413 4.46481517038362 1.54739406654906e-05 -65.0629778167692 39.1639719102929 -1.66129671336195 0.0987016186714974 ZNF343 other 0.00346483128985838 1 0.154151396909617 4.46481517038362 -1.66129671336195 0.00351505641032087 157.596351025332 47.2599846044547 3.33466784520443 0.00107620468742673 83.3899707048076 175.954794446059 0.473928380112267 0.636240085295557 EBF4 other 1 1 1 3.33466784520443 0.473928380112267 0.00358612327069372 1153.32860876558 352.381676251856 3.27295284202368 0.00132112915265616 341.575463840541 1311.960761951 0.260354938765538 0.794947053414119 CPXM1 other 1 1 1 3.27295284202368 0.260354938765538 9.5560971031545e-14 858.504601423241 110.601725671062 7.76212664146396 1.10991195275218e-12 -178.776631659761 410.704363080225 -0.435292750042785 0.663963375202634 MAVS other 1.24726179390372e-09 1 1.50592853749415e-08 7.76212664146396 -0.435292750042785 6.79178401871094e-10 739.473716513827 133.857818098479 5.52432220260604 1.43757993410691e-07 -980.931889439102 510.149915219145 -1.92283064286647 0.0564089406505839 LZTS3 other 7.72972939169492e-06 1 0.00165630749410999 5.52432220260604 -1.92283064286647 4.27504464143483e-11 459.878973014485 72.4153714689517 6.35057120726997 2.32386730887269e-09 -314.439805619555 254.538301502237 -1.23533395077986 0.218599782861129 XRN2 essential 5.13518362329152e-07 1 2.89763014743336e-05 6.35057120726997 -1.23533395077986 8.87666848314263e-05 115.86838007468 27.6931707844233 4.18400554333969 4.81089831463095e-05 18.132080718201 97.3408340203124 0.186274145898702 0.852476529180351 KIZ other 0.655186900740757 1 0.456159819263907 4.18400554333969 0.186274145898702 0.0166900612661555 -155.007915288144 257.681913555362 -0.601547517050867 0.548348551558682 -1413.56398591983 516.846445791109 -2.73497863326923 0.00696094045820861 DYNLL1 essential 1 1 1 -0.601547517050867 -2.73497863326923 0.0035619700804623 7.51309401969464 4.84789283800796 1.54976487120161 0.123237360520886 -17.7755103452091 9.39679341747221 -1.89165703187192 0.0604019284849944 TESC other 1 1 1 1.54976487120161 -1.89165703187192 9.15212074969019e-10 314.066965237791 68.3902258001812 4.59227852464494 9.05407749512081e-06 -674.723181915119 216.473242545977 -3.1168895239873 0.00218113529794393 SNX5 other 1.03528789920495e-05 1 0.0922338874427957 4.59227852464494 -3.1168895239873 7.09409917953782e-09 2159.90518804035 740.46979114759 2.91693896748023 0.00406740662465943 -5210.99704681299 1481.03874903629 -3.51847448299633 0.000571768140559509 RPL6 essential 7.63183189734679e-05 1 1 2.91693896748023 -3.51847448299633 0.536147730137871 2.27826168692819 3.63625378845435 0.626540890562153 0.531893926468885 -8.07175084597065 12.8500472067399 -0.628149509189119 0.530842510728615 SIRPG other 1 1 1 0.626540890562153 -0.628149509189119 6.1312336147537e-18 244.657935887412 41.6487581633639 5.8743152659621 2.55706456150966e-08 -325.562621260823 82.9033857398514 -3.92701236934315 0.000129761093471131 MAPKAPK5 other 8.54203467207486e-14 1 0.00030585049220217 5.8743152659621 -3.92701236934315 0.444177582315023 8.46733487888214 11.9638178684264 0.707745217455058 0.480159534098623 -14.1872296829864 25.9696552912741 -0.546300269443829 0.585640012665422 P2RX7 other 1 1 1 0.707745217455058 -0.546300269443829 2.05938966698045e-07 122.052275721495 22.5737917967057 5.40681321156271 2.45617097719612e-07 -23.6657958189367 70.1174616807209 -0.33751643672868 0.736196348448803 ESF1 essential 0.00199781391593773 1 0.00278873652750848 5.40681321156271 -0.33751643672868 8.41286545502343e-13 224.868323813634 29.9058964338359 7.51919690189308 4.24897107079514e-12 0.240986566435533 94.7692179843303 0.00254287807329358 0.997974370053817 RBBP9 other 1.07062125780628e-08 1 5.70849263361327e-08 7.51919690189308 0.00254287807329358 8.08836455375655e-15 401.402137052915 98.8730259478832 4.05977396974274 7.77179086701436e-05 -1042.58501823533 215.355753650694 -4.84122202709477 3.09534165414519e-06 ANAPC5 essential 1.08117168990064e-10 0.0450743651676622 0.719356962650849 4.05977396974274 -4.84122202709477 0.00166581407512418 129.416619407984 38.5789607333692 3.35459060969583 0.00100078396134638 -21.5512081375169 132.979844835168 -0.162063718484784 0.871468118320853 SLC23A2 other 1 1 1 3.35459060969583 -0.162063718484784 0.0341146570448402 40.1313650174106 58.7266809347476 0.683358302881128 0.495400680868678 -218.332366254271 117.98087290773 -1.85057425727832 0.0661343006500459 SLC8B1 other 1 1 1 0.683358302881128 -1.85057425727832 7.30695720652743e-12 812.378765631773 111.204269593054 7.30528394822097 1.39516603014173e-11 11.7789698578126 383.315834184759 0.0307291502394213 0.975525332239167 TMEM230 other 9.02409215006137e-08 1 1.85529178688248e-07 7.30528394822097 0.0307291502394213 4.39093232261531e-06 33.206881437153 7.34486035538939 4.52110453165893 1.22012922104399e-05 -12.1783609461408 23.2752318133766 -0.523232638187593 0.601564424940242 DZANK1 other 0.0375556441553287 1 0.122940220312392 4.52110453165893 -0.523232638187593 0.900950048151962 3.28910637574328 7.73815542706026 0.425050440863633 0.671397091785181 0.369952140667423 25.572069690224 0.0144670394359535 0.988476222821472 CFAP61 other 1 1 1 0.425050440863633 0.0144670394359535 8.51651863251352e-13 51.5359343428044 7.56439961623764 6.81295766450229 2.13118665093874e-10 -48.5883952403522 23.4774834520098 -2.06957425141717 0.0401961190284838 TASP1 other 1.0835566656147e-08 1 2.74859142371569e-06 6.81295766450229 -2.06957425141717 0.232820871979231 -121.834700489418 259.339978484321 -0.469787578457688 0.639180060448567 -861.012897222029 518.373373658586 -1.66098982118845 0.0987768114265822 OAS1 other 1 1 1 -0.469787578457688 -1.66098982118845 4.03200329011964e-13 1072.90778116118 182.41149573896 5.88179915314418 2.41478414013277e-08 -676.921929680425 356.954023498106 -1.89638408623797 0.0597698585955706 GCN1 other 5.18031782714571e-09 1 0.000289097957256695 5.88179915314418 -1.89638408623797 1.1863746166346e-06 2124.98862035332 2376.58852210015 0.894134007882656 0.372636461819951 -19129.6808280048 4650.65445424049 -4.11333093357693 6.31116225495951e-05 RPLP0 essential 0.0107568586490259 0.90710335090533 1 0.894134007882656 -4.11333093357693 1.89648455070331e-06 540.195995045015 173.074655030103 3.12117331651511 0.00214916313563768 -740.260673214792 348.655155229551 -2.12318866396056 0.0353260791920362 PXN other 0.0168673335939553 1 1 3.12117331651511 -2.12318866396056 0.000102570811348544 5.15085059618482 1.89301472302551 2.72097756743934 0.00725336068024771 -5.93774596093365 3.81680833172465 -1.55568355675084 0.121822829890455 SIRT4 other 0.751433763939432 1 1 2.72097756743934 -1.55568355675084 3.2828895144877e-08 53.5912526607834 11.1205812584222 4.81910535208722 3.444086372908e-06 -64.2626113705214 34.8470107084648 -1.84413555320862 0.0670974649344521 KIF16B other 0.000338433080048537 1 0.0363247789750607 4.81910535208722 -1.84413555320862 5.67509630582223e-18 165.062925933342 18.4193046122326 8.96140920671459 1.04166361382719e-15 -88.2589778290259 63.5134775188226 -1.38961022568587 0.166666056512433 TRMT6 other 7.90824670216328e-14 1 1.46041238658572e-11 8.96140920671459 -1.38961022568587 0.605004326761725 -5.89243866905108 7.63759473378884 -0.771504495123686 0.44159787215596 -23.0260445076607 26.3359671624203 -0.874319305064952 0.383314721727353 CHGB other 1 1 1 -0.771504495123686 -0.874319305064952 1.15874803001314e-06 286.803599634947 228.493923196468 1.2551913662419 0.21129839492212 -1757.87152409702 442.447939437045 -3.97305844916731 0.00010842043453427 PEBP1 other 0.0105144796243392 1 1 1.2551913662419 -3.97305844916731 6.13860766170233e-18 119.840433649138 20.946670207356 5.72121642546571 5.35239568294582e-08 -174.843952014582 41.1245899605877 -4.25156705956574 3.66694210246575e-05 BRAP other 8.55169433351751e-14 0.528699712333511 0.000630779831235165 5.72121642546571 -4.25156705956574 1.00624544960115e-09 236.370015637217 120.886475932662 1.95530570159795 0.0523690888388396 -1097.69972200504 240.628978796118 -4.5617935441396 1.03360696937695e-05 ERP29 other 1.13595048805474e-05 0.150100404092921 1 1.95530570159795 -4.5617935441396 0.366046053602567 -1.12362856738479 10.325191895428 -0.108823988819262 0.913483762940803 -25.8103941443606 20.0176827612782 -1.28937971753093 0.199199307368457 NOS1 other 1 1 1 -0.108823988819262 -1.28937971753093 0.0057189939768036 932.742062911486 291.664474123906 3.19799682739295 0.00168831292170421 483.530748597901 604.293522646467 0.800158748153229 0.424884249352497 FUS other 1 1 1 3.19799682739295 0.800158748153229 2.67695035988674e-08 484.807632515922 77.8124500386202 6.23046353475954 4.14078797270577e-09 632.874354345319 349.50522602119 1.81077222091937 0.0721002430663479 FXYD5 other 0.00027770683033465 1 5.11801393426433e-05 6.23046353475954 1.81077222091937 7.24638928589904e-27 198.589863200377 16.3960647833055 12.112044312156 3.18907374005352e-24 -82.851177268783 71.8145425961079 -1.15368244750574 0.250394855255515 ZNF302 other 1.04724817959813e-22 1 4.60215231427124e-20 12.112044312156 -1.15368244750574 2.1492636654663e-20 1070.52748106915 102.026592888662 10.4926318791943 8.00419139397448e-20 243.398901760193 458.266349279908 0.531129772331428 0.596084250569972 GRAMD1A other 3.04163793936791e-16 1 1.14563991421957e-15 10.4926318791943 0.531129772331428 5.88142198002841e-12 187.255934008337 24.7870608252767 7.55458403593306 3.40547522429322e-12 -2.43166813053352 78.4004440884709 -0.0310159994475223 0.975296681615704 CDIP1 other 7.28649369105719e-08 1 4.58274800933138e-08 7.55458403593306 -0.0310159994475223 4.66186030130947e-11 25.8233691040679 4.64840597948967 5.55531707385485 1.31205950007708e-07 2.61090092338408 7.22297929089378 0.361471467414522 0.718280553894826 CMTM1 other 5.59190143142071e-07 1 0.001514903898789 5.55531707385485 0.361471467414522 0.000672546729285916 102.083477750037 29.0320083468623 3.51623892258455 0.000576238334485496 7.20157144955204 93.8780154795905 0.0767120119951587 0.938952870523734 GMIP other 1 1 1 3.51623892258455 0.0767120119951587 0.0352538115009686 227.494153813815 93.0468161169143 2.44494291484371 0.0155862770046542 363.498791350273 376.401445634581 0.965721028880335 0.335659613271307 BIRC5 other 1 1 1 2.44494291484371 0.965721028880335 0.865108529129965 -6.43457439147342 12.6312975008312 -0.509415156364577 0.611230351789786 0.547061788852074 55.3788487023806 0.00987853308024002 0.992131684620625 LAG3 other 1 1 1 -0.509415156364577 0.00987853308024002 6.06414252003657e-20 1607.99848254151 161.350836454205 9.96585154361993 3.61945498512166e-18 -1016.30243204872 707.403460286799 -1.43666590440014 0.152952378123836 MLF2 other 8.56620772380366e-16 1 5.14795082533853e-14 9.96585154361993 -1.43666590440014 1.18432003119698e-12 68.8571126966427 9.27808345061787 7.42148020796873 6.86665472329512e-12 -0.423142022960095 16.236674258632 -0.0260608802159801 0.97924187495404 OTUB2 other 1.50053347952658e-08 1 9.1882706852412e-08 7.42148020796873 -0.0260608802159801 1.64546043929012e-10 735.740166516896 126.326579822645 5.82411213499037 3.1469375698177e-08 -350.883651101271 221.071898922267 -1.58719246006317 0.114481016395905 DDX24 essential 1.92897327297981e-06 1 0.000374831733940986 5.82411213499037 -1.58719246006317 1.06414503837086e-09 112.975339306307 24.9322027891779 4.53130195761706 1.15979527211502e-05 -73.2214782345366 36.0304930397559 -2.03220861157088 0.0438290172687719 ZBTB25 other 1.19971711625931e-05 1 0.117046538861848 4.53130195761706 -2.03220861157088 4.08485750832293e-15 117.335569504515 14.5760693744797 8.04987726732081 2.09265267683927e-13 -119.843957714791 66.7680702452025 -1.79492918208763 0.0746262021130764 NECAP1 other 5.4871890909302e-11 1 2.86630637146675e-09 8.04987726732081 -1.79492918208763 0.0477866563183132 5.86139944392954 4.78284726766078 1.22550420615799 0.222268424900788 -6.68920296570902 7.09446334124133 -0.942876528351841 0.347230509707261 ANKRD24 other 1 1 1 1.22550420615799 -0.942876528351841 0.00094426206317736 134.5403778391 42.1513499510383 3.19184030868235 0.00171184470086081 -33.5457949479942 78.1061502652202 -0.429489801175514 0.668163239653965 DHX32 other 1 1 1 3.19184030868235 -0.429489801175514 2.10817628888481e-08 447.610384113436 77.9385711376732 5.74311765765839 5.31660470866287e-08 16.4899180510974 136.472844296814 0.120829298576305 0.90399467733695 RCOR1 essential 0.000220325503951352 1 0.000626721363057179 5.74311765765839 0.120829298576305 4.20882526473753e-07 146.276774539603 33.5199915705064 4.3638666863004 2.32333782744335e-05 -73.0133625678713 53.0227706164677 -1.37701899993123 0.170491866801575 GPATCH2L other 0.00396976398970043 1 0.227524473441527 4.3638666863004 -1.37701899993123 4.91681660582876e-05 1536.9332597709 389.299528375599 3.94794534219948 0.000119887769316188 -300.629770703544 1306.60888150897 -0.230083979190739 0.818333847854852 LTBP4 other 0.374586708672687 1 1 3.94794534219948 -0.230083979190739 0.00172600915552812 27.3109507221242 56.7800057730141 0.48099591309137 0.631206537013699 -562.426797087583 190.520599046663 -2.9520524284612 0.00365456431317288 BLVRB other 1 1 1 0.48099591309137 -2.9520524284612 0.000146371717438898 138.195873259875 71.3236867661646 1.93758735037004 0.0545153506740461 -344.030604825906 156.858992857094 -2.19324756942265 0.0297989743297926 SLC9A1 other 1 1 1 1.93758735037004 -2.19324756942265 1.9800606885577e-10 348.109297959139 76.2658927786294 4.56441648129088 1.01367242995195e-05 -255.796945890888 115.598463031926 -2.21280576905458 0.028372756474924 SPTLC1 essential 2.31469094492395e-06 1 0.102897888364422 4.56441648129088 -2.21280576905458 4.56904693124471e-10 972.886609828353 170.712701663473 5.69897026025756 6.01702305669247e-08 -378.706022298108 281.717977416434 -1.34427353827799 0.180849720455285 PAPOLA other 5.24800730522767e-06 1 0.000707601911467035 5.69897026025756 -1.34427353827799 9.19482065972518e-12 548.647503209302 84.2154236053138 6.51481022978176 9.9268632424405e-10 -144.745324578173 136.514177630427 -1.06029518025615 0.290681256739021 CCNK essential 1.13215826783196e-07 1 1.25296867846084e-05 6.51481022978176 -1.06029518025615 0.0517149904187529 179.842241046394 108.929558907017 1.65099577057784 0.100980924819878 -227.207862126015 249.051525981427 -0.912292591786642 0.363182992934432 PCBP4 other 1 1 1 1.65099577057784 -0.912292591786642 0.114624828238535 -200.955336903974 97.2877829702997 -2.06557628068595 0.0406365106107398 -263.880614230407 386.358964322602 -0.682993378173752 0.495693379822142 RGS1 other 1 1 1 -2.06557628068595 -0.682993378173752 2.28751706085901e-05 298.951799363946 151.420358412739 1.97431707663159 0.0501227002046176 -976.091089661329 323.698944771582 -3.01542870444051 0.00299949855068789 YPEL3 other 0.182109233214986 1 1 1.97431707663159 -3.01542870444051 1.23213143518051e-05 154.525158464767 38.1321125202738 4.05236291020096 7.99770678759609e-05 -233.707434708264 134.023800080777 -1.74377561722177 0.0831808430982311 MRPS33 other 0.100825315340821 1 0.73954794664901 4.05236291020096 -1.74377561722177 6.98332746943135e-05 352.16129845438 95.1328598590242 3.70178399951649 0.000297039736646035 -536.362098447092 334.365618586684 -1.60411857150331 0.110723603284642 NDUFB2 other 0.522702061086937 1 1 3.70178399951649 -1.60411857150331 7.85766250398789e-10 315.095826371361 114.328575249461 2.75605486803131 0.00656641545373623 -842.278698140709 241.476753346523 -3.48803222864284 0.000636600477879856 NUDC essential 8.92001847452705e-06 1 1 2.75605486803131 -3.48803222864284 1.30961997658707e-17 652.078507709757 81.2106448496449 8.02947087684168 3.72567770325129e-13 -81.8382636951655 145.321941660911 -0.563151460542166 0.574239029375278 MAEA other 1.81880022348412e-13 1 5.08890317487094e-09 8.02947087684168 -0.563151460542166 0.0144257810906124 527.309043861295 186.666114344836 2.82487823626722 0.00535239240625677 324.316492676615 747.008832623215 0.434153491248206 0.664780716490504 ICAM1 other 1 1 1 2.82487823626722 0.434153491248206 3.56254806202828e-19 893.854847735192 112.851266521711 7.92064524648669 4.16040504164367e-13 -260.073702797459 232.280002674774 -1.11965601774855 0.264581292611999 STRN4 other 5.00965508482416e-15 1 5.6802010033561e-09 7.92064524648669 -1.11965601774855 0.855146220713371 -8.48434218786767 90.3578806641508 -0.0938970914933578 0.925314562790189 398.429024622407 753.833871952897 0.528536909054284 0.597897613154949 LYZ other 1 1 1 -0.0938970914933578 0.528536909054284 7.22671098826081e-09 83.7352258135021 32.5768912795305 2.5703872445962 0.0111002683669746 -231.250648889375 71.9087468566787 -3.21589040273891 0.00158294342322509 MUL1 other 7.77015965457802e-05 1 1 2.5703872445962 -3.21589040273891 1.19636570326167e-36 334.681278747996 19.4475319801585 17.2094474038895 1.62048119280631e-37 169.09377444031 58.9715534389142 2.8673786695388 0.00472702548022188 TFAP4 other 1.74071209824572e-32 1 2.35909652048742e-33 17.2094474038895 2.8673786695388 4.81180004714152e-09 162.542250867021 30.1079053207847 5.3986569020732 2.47424345903463e-07 -63.6913061850686 49.8497851571803 -1.27766460746511 0.203278001356538 PDCD7 essential 5.2294642912334e-05 1 0.00280826632600431 5.3986569020732 -1.27766460746511 2.86198197410385e-06 603.406841275235 129.212692091153 4.66987283919107 6.48701269736297e-06 -78.9182338543077 213.112667908156 -0.370312260781789 0.711655379420357 SPG21 other 0.0249564828141856 1 0.0669459710367859 4.66987283919107 -0.370312260781789 8.72209050826615e-08 373.307012932394 62.3517260783371 5.98711593747029 1.49564541687864e-08 31.8141099779203 263.754366952434 0.12062022079679 0.904152202591916 DNAJB11 other 0.000872209050826615 1 0.000180629096996433 5.98711593747029 0.12062022079679 0.0303804148251625 83.908359621997 32.1990628942182 2.60592551707659 0.0100862682076451 -0.287711680016171 122.866846005107 -0.0023416543141688 0.998134743225156 P3H2 other 1 1 1 2.60592551707659 -0.0023416543141688 0.49113269215508 -7.60283494616328 6.5329717730436 -1.16376363013448 0.246542602228979 4.28354572713643 26.8252946199229 0.159683082248613 0.873365913185837 CHRD other 1 1 1 -1.16376363013448 0.159683082248613 0.165337193701711 12.7650935594995 12.5539028107537 1.01682271656308 0.310802167887528 -15.2115986353569 22.1485474482109 -0.686798927601262 0.493222613418417 FLT3LG other 1 1 1 1.01682271656308 -0.686798927601262 7.57750563660481e-05 227.691801918904 64.3087607255811 3.54060316743643 0.00055340337519296 -39.6215196467679 138.054705810894 -0.286998689498068 0.774566776902354 RAB11FIP3 other 0.564881703720482 1 1 3.54060316743643 -0.286998689498068 4.4375383598733e-07 220.243716703228 55.3239445002284 3.98098361736153 0.000110837189530807 -184.169524582004 123.492602568502 -1.4913405398501 0.138171108786027 GNPTG other 0.00417661110431275 1 1 3.98098361736153 -1.4913405398501 6.97216719618671e-14 162.986000937107 24.9835312436101 6.5237375512636 1.05385776658494e-09 -55.7667877781522 47.7272959716896 -1.16844641295479 0.244531117340249 ZNF268 other 9.13563067716345e-10 1 1.32880925788694e-05 6.5237375512636 -1.16844641295479 1.53907764481778e-09 332.774839257552 62.2436175459668 5.34632870610065 3.3586186164171e-07 -75.4740567754457 118.671664301691 -0.635990547697833 0.525771527468487 GOLGA3 other 1.72068880690628e-05 1 0.00378046111463909 5.34632870610065 -0.635990547697833 1.21545721520521e-10 1461.09654300168 213.110064828317 6.8560654053517 1.75533477601151e-10 -1529.20770095559 1491.11274344309 -1.02554800613168 0.30676674984296 PABPC4 other 1.43399642249911e-06 1 2.27070106624849e-06 6.8560654053517 -1.02554800613168 0.415448808666207 1.6069625147258 19.095294250259 0.0841548966811026 0.933043288999842 68.0712041164778 57.2662011755255 1.18868028119823 0.236407202421389 CD209 other 1 1 1 0.0841548966811026 1.18868028119823 0.000133760001609466 235.383519696728 60.2707369928317 3.90543622728096 0.000140398899316005 60.1679752154276 197.808127988058 0.304173422130865 0.761406390549564 CERS4 other 0.964414852772235 1 1 3.90543622728096 0.304173422130865 6.8083157380978e-15 127.098800141564 19.646331343366 6.4693401490697 1.2758017450932e-09 -125.618377404735 58.9047724182199 -2.13256706116871 0.0345666619842542 MCOLN1 other 9.11156895229628e-11 1 1.6043206944547e-05 6.4693401490697 -2.13256706116871 1.60789840959734e-14 268.806236217031 49.2796692362144 5.45470861276585 1.93093048119367e-07 -234.129059788213 104.37026226997 -2.24325449314864 0.0263165905117416 USP48 other 2.13641461683199e-10 1 0.00220666735390813 5.45470861276585 -2.24325449314864 1.96914121699119e-15 886.58229339384 113.900470301956 7.78383347358851 1.03430973873326e-12 333.39728597609 184.12816739725 1.81068052047027 0.072178271821472 PDPR other 2.66090052652019e-11 1 1.40428233227815e-08 7.78383347358851 1.81068052047027 1.35091101104891e-09 1269.76957494408 219.891387173038 5.7745307411466 4.20995913338131e-08 480.13808103406 353.607771983433 1.35782671953419 0.176530953731761 AARS essential 1.51531688109356e-05 1 0.000498661616924264 5.7745307411466 1.35782671953419 1.03715742196792e-15 1897.49801044477 225.751040774852 8.40526805073384 2.66760821224457e-14 926.34352986795 380.103189728741 2.43708433630623 0.0159454610755796 GLG1 other 1.40721519012607e-11 1 3.69223652656771e-10 8.40526805073384 2.43708433630623 0.000226828535104457 157.591012231824 71.763610865741 2.19597384148706 0.0296092598820928 -273.161647439619 143.699705793626 -1.90092001880588 0.0592052538940118 TNRC6A other 1 1 1 2.19597384148706 -1.90092001880588 2.15922738571265e-13 646.280521280422 86.6895861338474 7.4551113934559 5.94310984796705e-12 -3.75290426897667 317.61618998246 -0.0118158468848327 0.990587732202482 PLEKHG2 other 2.79317654615788e-09 1 7.96138995233667e-08 7.4551113934559 -0.0118158468848327 6.32266829884732e-06 25.8361422524125 5.9678028475695 4.32925532433344 2.66463660168295e-05 -6.07590396225608 21.1445729685885 -0.287350516431908 0.774225293205939 DLL3 other 0.0531926083982025 1 0.259588897735953 4.32925532433344 -0.287350516431908 3.62806641257076e-09 130.052494154525 32.875443537525 3.9559160321618 0.000117244878263936 -144.777706527319 65.2756077218188 -2.21794498098447 0.0280617004255214 NAT14 other 3.97200710848247e-05 1 1 3.9559160321618 -2.21794498098447 0.0635331319673596 52.1598181205793 24.7606021190229 2.10656501283167 0.0368895900560554 6.29162456494892 55.3024088746808 0.113767640379033 0.909580453943212 PITPNM2 other 1 1 1 2.10656501283167 0.113767640379033 8.87697202807603e-16 274.576625659051 37.6488202909263 7.29310038235717 1.58995491484147e-11 -23.3985940246045 65.5432250622908 -0.35699485343248 0.721594066896424 EXOC1 essential 1.20575911057357e-11 1 2.11146012690947e-07 7.29310038235717 -0.35699485343248 3.28593292735392e-08 140.999316888046 31.0668723819366 4.53857456761652 1.12503451093609e-05 -76.6256492274328 46.5823515345237 -1.6449502161917 0.101993609706354 RBM27 other 0.000338681106822368 1 0.113673486984982 4.53857456761652 -1.6449502161917 4.55724145039141e-07 128.078581103077 38.7550823644027 3.30482025296172 0.00118383652430949 -191.885950492941 84.2055351786592 -2.27878072487534 0.0240635179169208 OSBPL8 other 0.00428380696336793 1 1 3.30482025296172 -2.27878072487534 2.38789903160358e-05 116.098521753738 25.1380383173737 4.61844000267508 8.18008792988014e-06 -1.91089646676723 92.075904043345 -0.0207534912268433 0.98346951665109 DTX2 other 0.189599183109324 1 0.083665939346814 4.61844000267508 -0.0207534912268433 0.320706008200639 2.0096496079182 1.39118315070798 1.44456149206198 0.150612645626023 -2.4123168985125 8.6255944355567 -0.279669640919861 0.780106246681917 NLRC4 other 1 1 1 1.44456149206198 -0.279669640919861 7.0545890014075e-12 162.289021204204 22.5925439040619 7.18330002559057 2.67611410134544e-11 -36.4938331611884 70.6189138449619 -0.516771374327672 0.606052326594445 PUS7 other 8.71735562903925e-08 1 3.53942851043948e-07 7.18330002559057 -0.516771374327672 3.35755463889651e-07 367.575866016537 70.0452157950094 5.24769410508014 5.09570008266832e-07 -117.365991096035 224.6522175747 -0.52243415339094 0.602128676919744 NRCAM other 0.00319169143973502 1 0.00567762903210904 5.24769410508014 -0.52243415339094 0.0834808457063765 439.034611016114 199.180642101665 2.20420321163552 0.029003566677971 196.196120770354 643.339645249409 0.304965071279406 0.760807213218264 LAMB1 other 1 1 1 2.20420321163552 0.304965071279406 5.48814734025358e-09 290.640353723836 49.8739062629716 5.82750330786942 3.21814643839334e-08 -157.699226567149 161.089254577487 -0.978955591921817 0.329147312234248 DLD other 5.94037068109048e-05 1 0.00038305597056196 5.82750330786942 -0.978955591921817 2.92628633124094e-13 95.6889848812093 21.7562958319201 4.39822043331556 2.03440435617054e-05 -64.0859919777849 39.6583167695537 -1.61595340392723 0.108164532398799 WDR7 other 3.77169045233645e-09 1 0.200592269518415 4.39822043331556 -1.61595340392723 5.79566438069225e-13 287.944458534794 84.8943817528077 3.39179640147707 0.000883850301342664 -414.329687230186 157.165629815795 -2.63626142506983 0.00924663404332471 TXNL1 other 7.41091604359118e-09 1 1 3.39179640147707 -2.63626142506983 0.0470912299496169 -15.7483065254347 18.5102136327648 -0.850790100961272 0.396260342764754 -87.6544919576303 35.5010169152591 -2.46906989078261 0.0146838215297201 IL5RA other 1 1 1 -0.850790100961272 -2.46906989078261 2.06224034898318e-06 1808.62887797052 449.630122406009 4.02248156394059 8.99805542797256e-05 -1363.51662154484 991.108933098582 -1.37574849343954 0.170897108941216 CMTM6 other 0.0182719950308282 1 0.827551157710636 4.02248156394059 -1.37574849343954 0.00107401518408936 230.020464146984 84.5340447592834 2.72103937297669 0.00725701929473716 -497.655341801582 273.780726429094 -1.81771503163306 0.0710513191054613 ITGA6 other 1 1 1 2.72103937297669 -1.81771503163306 0.0341322811560705 11.0469250616689 4.81772999298548 2.29297305530883 0.0232028547947067 -9.91543565170542 15.6032001186593 -0.635474490892924 0.526062146563824 RAPGEF4 other 1 1 1 2.29297305530883 -0.635474490892924 0.00286609634422379 236.99567933942 89.3538275364965 2.65232823118427 0.00883103202471337 -427.912160792582 289.105473739206 -1.48012472838404 0.140882833869885 MAP3K20 other 1 1 1 2.65232823118427 -1.48012472838404 8.13518235067923e-05 195.984416171295 57.4642390886797 3.41054574600473 0.000826773277037415 -184.462600472499 177.715255588008 -1.03796716754657 0.300901855011993 FH ts 0.603711882243905 1 1 3.41054574600473 -1.03796716754657 3.10619088173216e-05 442.667077790502 161.127255746131 2.74731345569467 0.00674028695017146 -433.572152233284 292.940268504753 -1.48007016736331 0.1409379081481 SEL1L3 other 0.242997312677907 1 1 2.74731345569467 -1.48007016736331 0.00663699204119699 11.6704442394194 3.66960786889853 3.18029736592057 0.00178348182188489 13.5619993256824 14.454105600968 0.9382800776531 0.349589027709945 TF other 1 1 1 3.18029736592057 0.9382800776531 3.52613912960112e-05 424.331117403372 93.1854508361369 4.55361983652944 1.07419779393033e-05 -166.235861241683 380.225995664192 -0.437202777130735 0.66258481628735 CDV3 other 0.273945748978711 1 0.108805494547203 4.55361983652944 -0.437202777130735 0.205138491058125 101.095822566753 56.7831031573089 1.78038565956289 0.0770785053145515 38.6913304180744 175.123071827359 0.220937938184509 0.825447338216615 MYO15A other 1 1 1 1.78038565956289 0.220937938184509 0.00022923819354121 426.477018267532 101.240086180644 4.2125311658325 4.36971739680279e-05 277.966411314095 312.823987289505 0.888571281641676 0.375675421781577 ALKBH5 other 1 1 0.415734913131817 4.2125311658325 0.888571281641676 0.00472827350126293 96.4155717081353 31.277923757448 3.08254385603765 0.00242735961958834 -99.412838194638 157.191656948246 -0.632430754434816 0.528031294461511 NLRP1 other 1 1 1 3.08254385603765 -0.632430754434816 0.694079566918955 27.7049884526562 36.6855356975941 0.755201959732407 0.451266495516334 -46.2363510392542 185.050963922271 -0.24985739095461 0.803026353672659 PITPNM3 other 1 1 1 0.755201959732407 -0.24985739095461 3.43884771490326e-16 225.747664023436 25.6592284527445 8.79791317339043 3.47123858445284e-15 -254.771352088488 127.787294271139 -1.99371426980772 0.0480333909994733 SPAG7 other 4.69884151764381e-12 1 4.84827893090529e-11 8.79791317339043 -1.99371426980772 0.034041026579335 40.6488642275013 25.3781583125378 1.60172632414462 0.11150276578991 -16.3466273625803 37.8349513670866 -0.432050968005223 0.666378693098403 ORC6 essential 1 1 1 1.60172632414462 -0.432050968005223 0.689207751259235 28.3712800850695 34.1101321620803 0.831755208401374 0.406860538887809 60.9929158741333 109.748992729004 0.555749208785352 0.579204810013244 ZFHX4 other 1 1 1 0.831755208401374 0.555749208785352 0.824236016726118 1.44114093607186 5.70505486260561 0.252607726091816 0.800908212870683 12.8161299924708 21.000461185079 0.610278501958652 0.542576870193157 CPA1 other 1 1 1 0.252607726091816 0.610278501958652 2.041979746949e-09 95.4012609033594 15.3692352520209 6.20728743746796 4.7749520944073e-09 -58.6683881739931 54.6879790760465 -1.07278398589956 0.285046238911479 ZC3HC1 other 2.26885005965065e-05 1 5.88656094198532e-05 6.20728743746796 -1.07278398589956 2.16518834773769e-09 1412.89286472261 247.313973967305 5.71295201018197 5.52043774094956e-08 22.3085144389243 493.580951850686 0.0451972758577461 0.964008242358201 ESR1 other 2.40032780230201e-05 1 0.00065014195275163 5.71295201018197 0.0451972758577461 0.00871972718606604 7.55434227982448 3.52215030783352 2.14480973825083 0.0335467436371392 -5.01307040749839 6.95433725852162 -0.720855233380511 0.472098572310781 RGS17 other 1 1 1 2.14480973825083 -0.720855233380511 0.691632009865354 21.477867449254 26.8430596438428 0.800127397331942 0.424919429993698 40.5543531425777 51.8386481319186 0.782318879909353 0.43527706693037 ANGPT2 other 1 1 1 0.800127397331942 0.782318879909353 1.15480819409135e-05 180.157780503916 38.6158960608795 4.66537873988189 6.58285910548369e-06 -193.855053316977 164.614783323086 -1.17762845719938 0.240738214441365 TMEM101 other 0.0948559450626635 1 0.0679087745321697 4.66537873988189 -1.17762845719938 2.05332399364157e-06 620.099189562427 299.378435212148 2.07128876574897 0.0401164875433661 -2788.65140154919 682.687869267051 -4.08481170837728 7.29215395530179e-05 PSME1 other 0.0181986105556453 1 1 2.07128876574897 -4.08481170837728 4.68982155058339e-05 67.7940294065739 23.934054009923 2.83253432028133 0.00525322443373116 -78.581864677161 39.3566558369464 -1.99666010757427 0.0476714967156836 PPP2R3C essential 0.358114773602548 1 1 2.83253432028133 -1.99666010757427 0.430902332676703 26.573761143795 29.2714874595928 0.907837744169242 0.365491316270067 78.0444013296059 66.9168951455972 1.16628844120454 0.245439257356527 JPH4 other 1 1 1 0.907837744169242 1.16628844120454 0.103570231013544 149.949416414614 148.166589215438 1.0120325858118 0.313196729555465 -525.338320766816 353.968243736709 -1.48413969349628 0.139927576933846 SLC7A8 other 1 1 1 1.0120325858118 -1.48413969349628 2.48912173474123e-13 106.476826462545 16.454098416177 6.47114316259715 1.3205944440133e-09 -164.465565989958 47.8735112206608 -3.43541891531406 0.000766691349173901 OSGEP essential 3.21494963259178e-09 1 1.65998721612471e-05 6.47114316259715 -3.43541891531406 5.17697869528322e-05 178.666759697464 38.8609663498203 4.59758921301991 9.22749045349491e-06 142.300982205866 91.2844170495095 1.55887485296299 0.121205955754044 SLC22A17 other 0.393605690202383 1 0.0939819902688456 4.59758921301991 1.55887485296299 9.68650362023428e-14 465.403802541751 64.7806793463694 7.18429950469228 3.5003663107753e-11 -350.334351159358 147.929936880204 -2.36824512027653 0.0192200293146004 RNF31 other 1.26408872244057e-09 1 4.6173332005437e-07 7.18429950469228 -2.36824512027653 5.57036010418353e-13 184.282492045856 38.4119564507085 4.7975294432694 3.78240894286535e-06 -244.984666178476 64.2974020556774 -3.81017985713226 0.000200702002674158 SCFD1 essential 7.12783278931324e-09 1 0.0398098541236578 4.7975294432694 -3.81017985713226 1.84076618746693e-11 140.350992374123 29.3602243881933 4.78031061746797 4.07528150063129e-06 -154.079743447301 49.1457953815771 -3.13515616648377 0.00205981186895654 G2E3 other 2.2427895228097e-07 1 0.0427782299121267 4.78031061746797 -3.13515616648377 2.00393163528082e-08 605.528801905777 110.518664058155 5.47897323104762 1.73621928721759e-07 -56.4956581083197 185.192921694513 -0.305063809088301 0.7607348823162 HECTD1 essential 0.000209771563581196 1 0.00199040179086624 5.47897323104762 -0.305063809088301 4.69373251589192e-08 637.016575306709 186.58099337055 3.41415577117007 0.000820417071680565 -2291.86838271824 625.558377592462 -3.66371623306968 0.000342762474571452 HNRNPC essential 0.000478291343369386 1 1 3.41415577117007 -3.66371623306968 9.77644886996645e-22 891.547639874298 85.6162477774607 10.4132996133125 1.67275220278838e-19 -420.040107558234 287.268533321573 -1.46218627811921 0.145754638769789 SUPT16H essential 1.39353502192502e-17 1 2.39170109954683e-15 10.4132996133125 -1.46218627811921 4.39756841000886e-31 520.58155266821 38.9173931122329 13.3765782093091 1.13622946780155e-27 -372.500015720858 128.767971997059 -2.89280020445897 0.00436447949944354 TOX4 other 6.37955249239985e-27 1 1.64639649884445e-23 13.3765782093091 -2.89280020445897 6.75864052966929e-08 48.3294215909712 15.4079445749472 3.13665598651965 0.00207241595754405 -77.4916287874017 23.341809939548 -3.3198637547 0.00114102313775596 GEMIN2 other 0.000682149588659522 1 1 3.13665598651965 -3.3198637547 0.193249796411846 5.2792680870703 111.976242016407 0.0471463231128685 0.962461930842204 -377.775776237676 232.639127921627 -1.62387032487907 0.106590499345512 TGM1 other 1 1 1 0.0471463231128685 -1.62387032487907 1.24214752625767e-09 244.484599479994 54.1365389169592 4.51607369756335 1.3012985906439e-05 -308.329207005587 112.472761860424 -2.74136779345932 0.00689438553737329 TINF2 other 1.39542853099787e-05 1 0.13067640447246 4.51607369756335 -2.74136779345932 0.00225077786009142 261.102818000928 76.9186004611948 3.39453417554904 0.000873071032691681 128.464556345344 114.793705035784 1.11909060087658 0.26483274007391 SEMA6A other 1 1 1 3.39453417554904 1.11909060087658 6.03162364011638e-13 305.732793853195 45.4161331466122 6.7318103209322 3.17137628784877e-10 -80.3207454634629 67.6598166673085 -1.18712626518646 0.237017690584688 TRPM7 essential 7.70901817443275e-09 1 4.06443585050698e-06 6.7318103209322 -1.18712626518646 0.000213237821248493 274.80311010785 79.6721771225265 3.44917284844915 0.000730219734530755 -28.9211053571165 117.080577189835 -0.247018814318139 0.805231424892139 TYRO3 other 1 1 1 3.44917284844915 -0.247018814318139 0.35119138686892 14.5790910086175 23.8966341375557 0.610089727477776 0.542798495938333 -34.1152765396186 41.5086873403526 -0.821882808769371 0.412551142781132 WDR76 other 1 1 1 0.610089727477776 -0.821882808769371 0.00255586383853837 29.9367835904508 17.443150168967 1.7162486879068 0.0883442893323771 -46.2017150736879 26.8116445672979 -1.72319586580079 0.0870768331377655 CAPN3 other 1 1 1 1.7162486879068 -1.72319586580079 1.00916326693343e-09 256.291977077363 60.2911289065543 4.25090691989849 3.86697974725276e-05 -223.045923417556 92.6768843440464 -2.40670502678465 0.0174012253953086 SNAP23 essential 1.13904257938776e-05 1 0.369683263837363 4.25090691989849 -2.40670502678465 2.60387868326133e-05 276.128219723922 60.7082903938075 4.54844334987381 1.32813269358446e-05 130.938878611071 211.538792901606 0.618982820195892 0.53713102509413 COL9A3 other 0.205914726272306 1 0.133224990493457 4.54844334987381 0.618982820195892 1.28232024355205e-10 1765.4204347409 355.728483138263 4.9628312559237 1.81126688186595e-06 -1102.19062884735 742.160207309765 -1.48511145975159 0.139545246371941 EZR other 1.51070147892867e-06 1 0.0194729302469409 4.9628312559237 -1.48511145975159 0.055412550874735 982.31826172948 1320.81415553067 0.743721785246018 0.458366581691734 -6846.1885177453 3601.29173208501 -1.90103691315827 0.0594771203817241 MYL6 other 1 1 1 0.743721785246018 -1.90103691315827 2.73437869216126e-11 439.181818181819 67.3194524360544 6.52384715397068 1.05326151188935e-09 -274.166666666666 239.977208090451 -1.1424696072109 0.25512896396798 AGO1 other 3.30941853112277e-07 1 1.32816276649247e-05 6.52384715397068 -1.1424696072109 0.611810367095598 -16.6199983301677 33.1928576985256 -0.500710076882169 0.617344970722807 -116.24497484815 118.226762066191 -0.983237405952708 0.327151236734368 TEKT2 other 1 1 1 -0.500710076882169 -0.983237405952708 0.00112596511448749 37.8271347869303 16.3525010576645 2.31323237060428 0.0220871997047914 -104.275795473132 57.0582793377805 -1.82753137114121 0.0696340635115245 CLSPN other 1 1 1 2.31323237060428 -1.82753137114121 1.35140531246818e-15 213.461964230804 23.8766015935667 8.94021552415229 1.2296221235467e-15 -109.345015027824 92.1577542468067 -1.18649825965798 0.237276796725522 RFFL other 1.83074877680064e-11 1 1.7233154061507e-11 8.94021552415229 -1.18649825965798 0.848465731366548 -7.62590179963538 51.4551177584301 -0.148204923666431 0.88237367392042 132.540637139611 238.101507188138 0.556656019127519 0.578565287147787 UNC13D other 1 1 1 -0.148204923666431 0.556656019127519 9.83783119898686e-06 382.986988598256 77.2222716309457 4.95954056400459 1.81769791537466e-06 229.741281019451 340.017786861821 0.675674302629394 0.500241464253866 MFSD11 other 0.0813588640156213 1 0.0195384348923622 4.95954056400459 0.675674302629394 2.21778954923659e-08 822.035483065139 161.711479978518 5.08334648334391 1.05588653382602e-06 330.147153236053 330.880834258746 0.997782642731975 0.319939893433511 DPYSL2 other 0.000231426339462838 1 0.0115260574032449 5.08334648334391 0.997782642731975 3.59174283273711e-07 484.220306786973 88.5766483678662 5.4666812947806 1.76859538701464e-07 162.524626313011 271.111907141295 0.599474320500086 0.549720758475441 TGFB2 other 0.00340425385686823 1 0.00202592601582527 5.4666812947806 0.599474320500086 1.16074893732081e-15 105.48817778078 14.3167339430673 7.36817336972735 9.24559270006791e-12 -96.9309782333372 43.6856306843819 -2.21882977800275 0.0279326811434087 GPATCH2 other 1.57420770879449e-11 1 1.23308469840806e-07 7.36817336972735 -2.21882977800275 0.00101466226289135 291.602269548887 78.0973855494934 3.73382882790727 0.000264960698676748 198.707491908738 121.832377865942 1.63099083666729 0.10493568293691 NUP50 other 1 1 1 3.73382882790727 1.63099083666729 0.000136986785534332 57.5217312458443 28.8782007413065 1.99187379300841 0.0483027275073134 -98.5311327698581 46.0379589455985 -2.14021505354503 0.0340460384007499 CDC45 essential 0.986030882276119 1 1 1.99187379300841 -2.14021505354503 0.000320696174991437 734.458243792771 192.962461681175 3.80622343534511 0.000209711623346818 208.80950176877 288.580231894391 0.723575209563164 0.470525274070506 ADA2 other 1 1 1 3.80622343534511 0.723575209563164 0.428094741392243 -11.0958536539439 9.48233148127055 -1.17016091199305 0.243720789390965 -3.70906848438057 19.5525855681693 -0.18969708489187 0.849793106715195 VNN3 other 1 1 1 -1.17016091199305 -0.18969708489187 5.19606731870461e-12 214.000502122608 49.1197585042542 4.35670916631388 2.43624253104589e-05 -223.922505743979 95.1040918416591 -2.35449917461798 0.0198433746172756 ECHDC1 other 6.44779993578056e-08 1 0.238045257708494 4.35670916631388 -2.35449917461798 1.45113658346942e-05 70.4962622471597 31.66188187563 2.22653418151435 0.0274202687693793 -204.951653387883 69.4912905112632 -2.94931425046228 0.00367862191446911 LRRFIP2 other 0.117757389507571 1 1 2.22653418151435 -2.94931425046228 1.47229711202566e-12 151.23727308603 27.3595600945734 5.52776698759959 1.33364186940778e-07 -180.909727703236 60.2349085585908 -3.00340337575618 0.00311075297372052 SEC22C other 1.86054186046683e-08 1 0.0015387559889227 5.52776698759959 -3.00340337575618 0.00342308646708573 21.0026577049369 11.0695372502078 1.89733836475799 0.0596429332013802 -42.3546912664862 24.3647957397625 -1.73835609864625 0.0841338780285757 XYLB other 1 1 1 1.89733836475799 -1.73835609864625 0.262323264055458 167.147493669989 111.150706130482 1.50379155912669 0.134709987462992 -10.8415018503105 183.568324567557 -0.0590597635831259 0.952982081702248 GABRP other 1 1 1 1.50379155912669 -0.0590597635831259 6.67017364367056e-07 138.379627242256 26.5077985614253 5.22033645765018 5.77666664030778e-07 -104.518895723599 106.92297777385 -0.977515758536618 0.329867087237352 CDC6 essential 0.00617658079403893 1 0.00640747863742939 5.22033645765018 -0.977515758536618 2.78312900153769e-05 196.440621667703 51.4095166559477 3.82109450634128 0.000191895256829807 -41.6365194135726 76.5158814887983 -0.544155260364714 0.587116549636095 CDC23 essential 0.219338396611185 1 1 3.82109450634128 -0.544155260364714 2.75630536530493e-11 197.132810691601 41.5434904136294 4.74521540508129 5.14174788527603e-06 -448.883527373828 109.466457237389 -4.10064908194094 7.00201859485349e-05 AAAS other 3.33568075309203e-07 1 0.0535255954857235 4.74521540508129 -4.10064908194094 0.000514479256989213 207.364724495014 85.1810202886812 2.43440057177348 0.0160596615303086 -80.5380257606755 119.618012774572 -0.673293460512966 0.501769787196874 MAP3K1 other 1 1 1 2.43440057177348 -0.673293460512966 1.01553914674547e-12 205.992805103947 36.3798533444429 5.66227695185067 7.52595977184275e-08 -443.940465105903 153.765707337077 -2.88712270631786 0.00447075735708434 DHPS essential 1.28922694679338e-08 1 0.000879784697328417 5.66227695185067 -2.88712270631786 2.51843875707151e-07 344.349697881326 93.7881632666518 3.67156884075334 0.000336003129429368 -1290.49435242349 469.523318842235 -2.74852025583231 0.00673192147646266 HOOK2 other 0.00242097517717285 1 1 3.67156884075334 -2.74852025583231 5.72241084679147e-14 947.68322605507 136.851464561493 6.92490379325998 1.11113956546373e-10 -902.191667820737 383.340230389857 -2.3535011363227 0.0198607201052827 ARCN1 essential 7.51810337051464e-10 1 1.44559257466832e-06 6.92490379325998 -2.3535011363227 1.42570963648618e-07 132.652871138859 42.8444021188248 3.09615409665326 0.00232004041188162 -207.738985267287 68.8659989261761 -3.0165682413172 0.00298033528946539 EPB41L4B other 0.00140133000170227 1 1 3.09615409665326 -3.0165682413172 1.05997144698986e-05 117.39465781571 34.7624213709489 3.37705640706081 0.000923730539469136 -78.3223319012794 54.5210025028437 -1.43655340705069 0.15283463977417 TMEM38B other 0.087384046089844 1 1 3.37705640706081 -1.43655340705069 1.41277048168646e-09 266.263397935255 73.5907229028302 3.61816527182144 0.000401034145234351 -354.862600070082 109.61539887412 -3.23734259707069 0.00147563822831633 PSMD5 other 1.5820203853925e-05 1 1 3.61816527182144 -3.23734259707069 5.84003639249703e-05 3001.54740254445 847.862724004365 3.54013370038072 0.000527388881537893 -992.561975004078 1260.30722054041 -0.787555572821741 0.432151668077843 PTGS1 other 0.441156349089226 1 1 3.54013370038072 -0.787555572821741 4.63772601003515e-12 801.434333461918 115.537209949873 6.93659067766675 1.02515213767825e-10 145.060847875409 157.364169485921 0.921816245396239 0.358057025656895 NUP188 other 5.76515720307469e-08 1 1.33567072018099e-06 6.93659067766675 0.921816245396239 0.000617732772253237 159.225237397955 122.912499692324 1.29543567819814 0.197071473377879 -381.247006994677 169.514552704079 -2.24905178294762 0.0259001586714964 CRAT other 1 1 1 1.29543567819814 -2.24905178294762 0.737703651243547 11.8176628813381 19.2708329208983 0.613240897777825 0.540621710620256 19.756122308976 26.5926906730873 0.742915508319354 0.458664608141151 SH2D3C other 1 1 1 0.613240897777825 0.742915508319354 1.14126959644738e-07 90.7473576542791 46.2650756083018 1.96146567278052 0.051604840716384 -258.55703418002 69.3417887847823 -3.72873326043708 0.000268813730461693 NANS other 0.00112997102744256 1 1 1.96146567278052 -3.72873326043708 0.0012907002939124 136.663262018301 76.1088397655653 1.79562929141029 0.074489043386244 -209.135439489625 113.734594321441 -1.83880235153921 0.0678456606051457 TBC1D2 other 1 1 1 1.79562929141029 -1.83880235153921 0.000470611956734206 70.1674763166918 31.4280202302766 2.23264067550444 0.02697822119437 -95.9086029147401 51.4435917821556 -1.86434499598856 0.0641284297625224 WHRN other 1 1 1 2.23264067550444 -1.86434499598856 5.75684233692924e-10 87.2576238546357 26.0407730778453 3.35080773500046 0.00101075576402314 -148.702336801781 47.9419393974941 -3.10171717436934 0.00228413690233519 CWF19L1 other 6.57776805417535e-06 1 1 3.35080773500046 -3.10171717436934 0.00461666609395827 99.3226026333501 51.3401766949812 1.93459798986355 0.0548726614359905 -109.778581166198 94.3783081640036 -1.16317598081365 0.246557268724462 SEMA4G other 1 1 1 1.93459798986355 -1.16317598081365 4.44067113003871e-05 135.245815801776 53.716690398293 2.51776151507045 0.0128126471790077 -151.571804062128 93.3240030882274 -1.62414597580896 0.106350654826722 BTAF1 other 0.340244221983566 1 1 2.51776151507045 -1.62414597580896 7.89951183012503e-05 71.7944772885839 20.3223674500476 3.53278118137834 0.000542059605966646 -30.4291392795506 36.8559117221374 -0.825624380396847 0.410286142706947 IKZF5 other 0.5875656899247 1 1 3.53278118137834 -0.825624380396847 0.643461996054351 -10.2199184438882 16.1053029119683 -0.634568533094369 0.526627619903599 -26.5526664956526 28.5260390832724 -0.93082206114003 0.353365668413618 BLNK other 1 1 1 -0.634568533094369 -0.93082206114003 0.395238297540502 1.1593811394892 5.26297128973902 0.220290226881836 0.825929512827564 -9.17362475442042 9.33025087341156 -0.983213086002062 0.327005758890017 TLL2 other 1 1 1 0.220290226881836 -0.983213086002062 0.757896624086637 -2.20556970631811 4.7294978483945 -0.466343315298648 0.641624515866152 -6.24421059040815 8.39267078010861 -0.744007569700874 0.457998290232926 CYP26A1 other 1 1 1 -0.466343315298648 -0.744007569700874 0.00210638444767743 29.8566990972759 42.8697807878577 0.696450939299704 0.487169778290567 -194.009483047429 76.1923513790352 -2.54631179555395 0.0118432000763893 SORBS1 other 1 1 1 0.696450939299704 -2.54631179555395 0.159145366489003 477.803494503223 255.738695111854 1.86832694322712 0.06356807728689 310.802219388634 444.245707865263 0.699617832847804 0.485194742260817 CRTAC1 other 1 1 1 1.86832694322712 0.699617832847804 0.000516898919778379 70.4813375600776 17.7341670242271 3.9743246730332 0.000107084258478375 128.031158881552 75.3330602291048 1.69953481900484 0.0911863466874833 BAMBI other 1 1 0.97607301603039 3.9743246730332 1.69953481900484 0.0461784519930163 9.71160705272724 4.50020574654071 2.15803623205284 0.032505767812933 1.43058312863826 8.93065783381416 0.160187878122667 0.872947167320013 IL11 other 1 1 1 2.15803623205284 0.160187878122667 0.622722940208104 17.4912293947398 19.4730289219126 0.898228491565441 0.370439190486024 -2.7297848244626 81.303093195018 -0.0335754116748644 0.973258377722614 MYO3A other 1 1 1 0.898228491565441 -0.0335754116748644 1.25669264526943e-10 526.233610580293 82.0716839053738 6.41187783093405 1.58414208509701e-09 -311.956383783115 349.815663104971 -0.891773630186208 0.37387035356152 WAC essential 1.48189196730171e-06 1 1.98619734629463e-05 6.41187783093405 -0.891773630186208 1.57787859236679e-09 351.041121622795 64.8630883266425 5.41203218469949 2.70587220390173e-07 -91.7698519960483 139.463856508822 -0.658018889576908 0.511630176002831 NUBP2 essential 1.7624903876737e-05 1 0.0030646708581391 5.41203218469949 -0.658018889576908 0.785824854603536 -8.48021888275254 17.4210235318808 -0.486780748974569 0.627197293588768 -25.8928230008378 37.9147716434353 -0.682921771080243 0.495817961646786 TPSD1 other 1 1 1 -0.486780748974569 -0.682921771080243 0.403302214840518 51.0916086276869 37.8930648574512 1.34831027313011 0.179604637376715 42.2668300809488 56.7069896360709 0.745354855763021 0.457231376243875 SMIM24 other 1 1 1 1.34831027313011 0.745354855763021 1.30438809709611e-07 164.539568778607 36.6322380263008 4.49166028732596 1.39033914116258e-05 -139.980787761985 101.365716846027 -1.38094803763499 0.169321930070953 HIVEP1 other 0.00128560490849793 1 0.139075624290493 4.49166028732596 -1.38094803763499 0.147135579573798 -15.6125021583514 9.90348495869518 -1.57646547891647 0.116983991647996 50.4719599311301 64.5388907730105 0.782039469947584 0.435399965774708 TREM2 other 1 1 1 -1.57646547891647 0.782039469947584 0.534002545566579 -117.969695369833 176.819046955966 -0.667177532063113 0.505697627372481 -553.345350599983 504.223422894135 -1.097420955623 0.274239701648765 CRISP3 other 1 1 1 -0.667177532063113 -1.097420955623 0.068030791947308 -122.862913967153 99.7022694233444 -1.23229806781495 0.219740526176154 -667.468521922554 286.646227267228 -2.32854459061239 0.0212008448696003 FKBP5 other 1 1 1 -1.23229806781495 -2.32854459061239 4.86839060142972e-12 333.144044088261 64.4987266161104 5.16512591126177 7.33370822922508e-07 -557.569150838224 186.709781444205 -2.98628784483282 0.00328628847830628 SRPK1 other 6.04654112697571e-08 1 0.00807587950202266 5.16512591126177 -2.98628784483282 1.84158144402509e-09 330.393210071306 73.5259293637514 4.49356047492807 1.36827319989945e-05 -535.300624723923 212.841569473081 -2.51501915743778 0.0129286660865791 BRPF3 other 2.04968014719992e-05 1 0.136977830041934 4.49356047492807 -2.51501915743778 8.68783770042162e-08 158.745159059475 51.0630811019607 3.10880494544579 0.00227590330428684 -500.287073786758 155.049207591053 -3.22663418639508 0.00155976197163664 MRPS18A essential 0.000869044405173174 1 1 3.10880494544579 -3.22663418639508 1.97160841341343e-05 68.3917887395489 29.3356666602999 2.3313528044721 0.0210658546807664 -246.832881423414 87.6402383922417 -2.81643324974415 0.00550967728226546 TMEM14A other 0.157807537409611 1 1 2.3313528044721 -2.81643324974415 1.13057031499226e-05 142.841513474924 40.3822232463735 3.53723747708101 0.000538379971639108 -195.458548991612 120.641801432465 -1.62015608744891 0.10729918186262 EFHC1 other 0.0929554912986635 1 1 3.53723747708101 -1.62015608744891 8.01573559797203e-18 8995.12106018229 1149.08266736402 7.82808871429327 1.03895874071779e-12 -8588.69307823845 3504.64520872636 -2.45065978628967 0.0154747413873653 HSP90AB1 other 1.11514913638987e-13 1 1.41049038639848e-08 7.82808871429327 -2.45065978628967 2.14058915867338e-20 322.255260263708 36.2951626618834 8.87873855989451 2.56268593297296e-15 -251.538949921242 106.779054350286 -2.35569561326208 0.0198459739131439 CDC5L essential 3.02957583627043e-16 1 3.5826349342962e-11 8.87873855989451 -2.35569561326208 0.00039047296819063 586.423176278278 251.803478511561 2.32889227640814 0.0211731955036986 -1436.94680229357 724.763413231434 -1.98264257833711 0.0491978919846858 ITPR3 other 1 1 1 2.32889227640814 -1.98264257833711 1.64953619890378e-12 80.8266039385486 12.0306091581358 6.71841324708722 3.69845898414605e-10 -41.6089012864815 34.3253493431942 -1.21219163337463 0.227370618860698 ZNF184 other 2.08039505405745e-08 1 4.72810996533231e-06 6.71841324708722 -1.21219163337463 1.27616217448172e-16 3522.02160088307 417.687700061757 8.43218893053907 2.13563411497256e-14 -467.465917224199 1141.7549556502 -0.40942753513865 0.682787546849581 DSP other 1.75280874665064e-12 1 2.96020244676347e-10 8.43218893053907 -0.40942753513865 1.13246538486008e-10 139.996790299572 24.2399577025698 5.77545522221477 3.99606973562216e-08 -98.0693295292438 52.1410616033078 -1.88084642916097 0.0618445712557435 SIRT1 other 1.33823434528916e-06 1 0.000473734067158007 5.77545522221477 -1.88084642916097 2.23601224248463e-05 490.670234482758 116.997895309534 4.19383813003323 4.61297384308155e-05 -129.560062528736 251.246412451037 -0.515669303552681 0.606824913085496 HNRNPH3 other 0.1781878156036 1 0.438047996139024 4.19383813003323 -0.515669303552681 1.00135743472728e-20 164.033938814532 16.9928958580323 9.65308916060912 2.10826387701771e-17 -11.5546526449967 37.6496053233067 -0.306899701757136 0.759351092547794 IFT74 other 1.42072592839106e-16 1 2.98656660818329e-13 9.65308916060912 -0.306899701757136 3.67106399683311e-10 82.0405024352731 12.6506901324599 6.48506141374599 1.30663975792586e-09 38.6116594035718 30.6256618600303 1.26076163121111 0.209419641996643 JAK2 og 4.23824338434383e-06 1 1.6425768396886e-05 6.48506141374599 1.26076163121111 0.994715719208009 -0.437910174152158 4.48072437513925 -0.0977320043566724 0.922273015876381 -1.1422089825848 15.8966638715564 -0.0718521188982634 0.942813434318448 IL12RB1 other 1 1 1 -0.0977320043566724 -0.0718521188982634 9.05140531492307e-08 863.002954709698 153.253142990633 5.63122516033778 7.98744254518346e-08 339.481239575424 211.639137276385 1.60405699977924 0.110698563344396 ABL1 og 0.000904054362854516 1 0.000932454042724718 5.63122516033778 1.60405699977924 0.00185513635233198 131.020100459468 55.5420165743017 2.35893668506248 0.0196612335927468 -118.194804683083 126.592740231098 -0.933661791879343 0.352030540054601 ACOT7 other 1 1 1 2.35893668506248 -0.933661791879343 1.74688289450062e-06 165.244854398536 58.6829890607007 2.81589021015289 0.00549680194428282 -722.63627585506 192.639867517666 -3.75122909482271 0.000248146390208353 SH3GLB1 other 0.015590929833418 1 1 2.81589021015289 -3.75122909482271 0.0125282662176989 45.9466540157392 28.0442421078579 1.63836319195323 0.103374310388547 -189.781994753586 95.8273973074769 -1.98045653003223 0.0494221561574628 CDC7 essential 1 1 1 1.63836319195323 -1.98045653003223 5.61283976860271e-07 44.7088315368819 8.72988549152476 5.12135371996421 8.9471081460387e-07 -28.3259723924913 28.1421423504746 -1.00653219785926 0.315738518495802 SYDE2 other 0.00523285051626831 1 0.0098024516848 5.12135371996421 -1.00653219785926 0.0782350833004669 134.46460711034 89.5244023673263 1.50198832446398 0.135121608868232 -118.700166218477 129.775060700661 -0.914660841440641 0.361781306105207 PCSK5 other 1 1 1 1.50198832446398 -0.914660841440641 0.0128021034876402 -752.299450225191 390.83148195428 -1.92486911868884 0.0560654698292989 -2146.26500181188 719.533908093765 -2.98285456414126 0.00331510882619612 SCD essential 1 1 1 -1.92486911868884 -2.98285456414126 2.11054567235207e-16 146.651712396904 18.59448386779 7.88683963693871 5.32379225088027e-13 -129.572834521053 75.2497114111513 -1.72190473679148 0.0870946183480276 TMED1 other 2.89102546198786e-12 1 7.25952311330033e-09 7.88683963693871 -1.72190473679148 1.18470006958241e-05 1440.44212952398 352.832445414703 4.08251040470769 7.13636713076892e-05 -310.850737072705 645.649568153562 -0.481454263125553 0.630877099026508 ABLIM1 other 0.0971217117043663 1 0.662897142777125 4.08251040470769 -0.481454263125553 6.52331345165585e-14 462.822426507728 73.0428113733242 6.33631726115014 2.56845442002779e-09 -220.975942014345 171.147620074657 -1.29114235954874 0.198627434781789 ERMP1 other 8.55597792319182e-10 1 3.1972120620506e-05 6.33631726115014 -1.29114235954874 3.95040682548647e-05 159.081639828842 53.3937203969795 2.97940729070906 0.00335057704413063 -480.114405416036 222.536653292274 -2.15746214528294 0.0325002755141096 RAB18 other 0.304220829630713 1 1 2.97940729070906 -2.15746214528294 0.457588173147108 59.3777410987977 77.2671354529417 0.768473436354591 0.443406170587952 437.308491511436 367.707325995427 1.18928414147744 0.236194640979437 NRP1 other 1 1 1 0.768473436354591 1.18928414147744 0.00108475939683748 83.9704032781564 25.9087121889422 3.24101030826205 0.00145438594801181 -70.8422792924374 107.754878980819 -0.657439180132599 0.511861258562767 PRTFDC1 other 1 1 1 3.24101030826205 -0.657439180132599 0.655775703618604 4.45369774919598 61.0225503850125 0.0729844577307249 0.941913811255259 -164.986148899332 192.502566474569 -0.857059476768733 0.392752456357031 PALMD other 1 1 1 0.0729844577307249 -0.857059476768733 0.0315285713453947 137.653689911984 104.886105582589 1.31241110676565 0.191296878079578 -375.706459038592 231.883793054848 -1.62023595564406 0.107188436335457 TSPAN15 other 1 1 1 1.31241110676565 -1.62023595564406 2.58348817123273e-05 317.501535660727 84.9818212843851 3.7361112160474 0.000261153481403576 -220.440947460101 186.385023050371 -1.18271813825152 0.238708860757559 H2AFY2 other 0.204379749226221 1 1 3.7361112160474 -1.18271813825152 2.19907252512535e-07 284.175853028463 54.5965730930561 5.20501263960478 6.07192610941965e-07 -34.3038572724615 114.956367508267 -0.298407630790827 0.765791725797556 WASHC2A other 0.00212584341003868 1 0.0067295157070698 5.20501263960478 -0.298407630790827 3.85758017052216e-07 126.746457025142 27.0641752525991 4.68318194965021 6.21507176541847e-06 -82.3951844084286 95.9367623809436 -0.858848916344035 0.391776252116465 MAST3 other 0.00364695629321165 1 0.0642451968391307 4.68318194965021 -0.858848916344035 3.13550012737749e-09 189.586654125378 61.9087608085634 3.06235582249215 0.00265462042389653 -310.844231890202 107.985473710334 -2.87857450830866 0.00465121772933366 MZF1 other 3.44779594006429e-05 1 1 3.06235582249215 -2.87857450830866 4.35609434730299e-21 107.30458448528 9.86392633175851 10.878485997994 7.76848699925637e-21 -69.534475635731 95.6482324387387 -0.726981292417158 0.468333960658226 OCEL1 other 6.19131689582175e-17 1 1.11493325413327e-16 10.878485997994 -0.726981292417158 1.61948063109393e-34 762.465760527539 47.5750118375922 16.0266015935085 1.03566113651751e-34 155.459805524393 461.382714915928 0.336943280488348 0.736615452033962 MYO9B other 2.35440094148435e-30 1 1.50626555695107e-30 16.0266015935085 0.336943280488348 0.34301924209577 9.61933794605303 14.963267023171 0.642863482363659 0.521281250520117 -52.7461572445061 57.1999272526298 -0.922136788942876 0.357918596231373 KCNK6 other 1 1 1 0.642863482363659 -0.922136788942876 6.89991099539754e-07 8.19406445163895 3.79068630240849 2.16163084938806 0.0322117888564463 -54.2748298120626 14.4906176170981 -3.74551528763144 0.00025499954514695 CATSPERG other 0.0063803476974441 1 1 2.16163084938806 -3.74551528763144 5.21268726113906e-17 1091.15770165823 129.821986281852 8.40503009474262 2.76018457533396e-14 -523.502788403727 492.350920746286 -1.06327167543471 0.289334061159943 PSMD8 other 7.19246588291968e-13 1 3.82009545226221e-10 8.40503009474262 -1.06327167543471 0.000116487084956467 188.440550688361 50.0344517064737 3.76621596243014 0.000236432221672304 -31.9785215390206 103.000183320172 -0.310470530325337 0.756628474566027 FBXL19 other 0.847793004313168 1 1 3.76621596243014 -0.310470530325337 0.394730562639534 -3.41346013167522 6.50305969627491 -0.52490063002659 0.600427203918032 -18.3911728846623 13.4735533480597 -1.36498311986205 0.174302225402077 STX1B other 1 1 1 -0.52490063002659 -1.36498311986205 0.00365712484045861 20.4159473299196 74.5969936816273 0.273683245427461 0.78470454609056 -453.202487198245 154.555950724244 -2.93228753130859 0.00389268048185246 HSD3B7 other 1 1 1 0.273683245427461 -2.93228753130859 1.13077204146503e-08 490.440281934922 81.3241628510336 6.03068343701603 1.20416329345038e-08 107.373267677255 168.405279270442 0.637588489757644 0.524707201245443 SETD1A essential 0.000120155837126074 1 0.000146113174027269 6.03068343701603 0.637588489757644 0.000331408501937846 194.970446803017 125.511449638227 1.55340765615406 0.122391862313862 -697.772343225394 258.231450478411 -2.70211990806182 0.00766806140404941 BCL7C other 1 1 1 1.55340765615406 -2.70211990806182 0.00156536438135381 23.5104031209363 7.77815454698999 3.02261969454366 0.00298451122315134 -5.7345578673602 11.6704087386706 -0.491375923137841 0.623935579004943 EFNA2 other 1 1 1 3.02261969454366 -0.491375923137841 0.00400049217714484 345.019180754227 164.475622780266 2.09769189453176 0.037742649160402 -349.35503040618 246.780612778633 -1.41565022662278 0.159114671559585 CIRBP other 1 1 1 2.09769189453176 -1.41565022662278 0.00857148938854027 420.594928478545 411.747590448231 1.02148728550101 0.30879817293 -1344.96111259848 617.789560320983 -2.17705380437262 0.0311647744708665 ATP5D other 1 1 1 1.02148728550101 -2.17705380437262 0.52490510103074 1.72399219765932 10.980995356234 0.156997807733394 0.87547438984803 -15.3547818021877 16.4759781244367 -0.931949635173033 0.35297845461393 CBARP other 1 1 1 0.156997807733394 -0.931949635173033 0.00332309051830157 26.3332630717536 9.58525793842179 2.74726702619015 0.00681813335476948 -5.85026844056485 20.6095187912139 -0.283862447242529 0.776944345786285 IGFALS other 1 1 1 2.74726702619015 -0.283862447242529 4.5969244182134e-06 351.782374164338 75.9881486014009 4.62943736147103 7.80854823765382e-06 99.1454847723811 251.412467354083 0.394353891100981 0.693872520022577 HNRNPM essential 0.0392163622117785 1 0.0799985766947633 4.62943736147103 0.394353891100981 1.82049743849557e-07 67.8138028460188 22.1276042397278 3.06466990783694 0.00257901669553107 -206.015918409537 73.6926566396066 -2.79560987218925 0.00584908367494827 MARCH2 other 0.00177334655483854 1 1 3.06466990783694 -2.79560987218925 4.93272762311611e-08 467.385185328375 92.3348309168247 5.06185131534379 1.18484614516168e-06 -1219.37413120122 656.582451038287 -1.85715309520223 0.0652244945395968 NDUFB7 essential 0.000501806381099601 1 0.0128899412132139 5.06185131534379 -1.85715309520223 0.000270035002796761 216.353065012288 96.8529692066065 2.23382996705826 0.0270357008142374 -297.711019264809 143.111959215868 -2.08026653325139 0.0392731007601602 TIMM13 essential 1 1 1 2.23382996705826 -2.08026653325139 0.000175908748056225 246.410726904414 79.8862043552568 3.08452165042936 0.00246023800993 -147.067461252179 119.228153721308 -1.23349608848213 0.219472500145118 CDC34 other 1 1 1 3.08452165042936 -1.23349608848213 8.24152892989667e-21 326.59348933568 34.6370899426926 9.42901063212966 6.9536709027325e-17 -80.7811382672903 83.1208270217922 -0.971851955300102 0.332678412326234 MTAP other 1.16988503159883e-16 1 9.82553698556103e-13 9.42901063212966 -0.971851955300102 0.000335560900246498 534.797649220332 148.593489335642 3.59906515158505 0.000443203684562302 -27.6590851274315 221.772051025348 -0.124718534186574 0.900926570841167 MISP other 1 1 1 3.59906515158505 -0.124718534186574 1.764105811387e-09 977.456396007689 147.905699611042 6.60864590464177 7.01859913969191e-10 393.451690184591 302.559717499518 1.30041002627925 0.195537865384495 CEP170B other 1.96591951620968e-05 1 8.89747812938743e-06 6.60864590464177 1.30041002627925 0.0017317597161922 301.210251095303 163.513615832508 1.84211112672012 0.0675899226274592 -476.497055636689 244.039965114731 -1.95253697652625 0.052883983859712 POLR2E essential 1 1 1 1.84211112672012 -1.95253697652625 3.91870548774892e-07 368.921411409996 75.9243366144018 4.85906664267142 3.13909721586569e-06 -53.4682526970366 113.31516561726 -0.471854340112198 0.637770626012641 POLRMT essential 0.0037035685564715 1 0.0331990921549955 4.85906664267142 -0.471854340112198 0.131068924659206 5.14523013143637 4.86243574137211 1.05815899789854 0.29181840372417 14.7003533235973 7.25706322776551 2.02566146417931 0.0447132976788247 HCN2 other 1 1 1 1.05815899789854 2.02566146417931 0.519543181416154 -6.4930558240229 28.8731350503218 -0.224882258636148 0.822378985850479 -53.2895677890749 49.8811533226523 -1.06833070687792 0.287099136722096 CDHR5 other 1 1 1 -0.224882258636148 -1.06833070687792 0.594113744883042 -4.0850914731 4.76293086605764 -0.857684393912125 0.392532658141157 -6.31740885392336 7.15902463809273 -0.882439881587893 0.379051628295536 IZUMO4 other 1 1 1 -0.857684393912125 -0.882439881587893 0.00655833614142238 234.888859357483 122.129894942642 1.92327078859601 0.0563531899416506 -241.102456798237 210.991290148988 -1.14271284197555 0.254990665144896 RASSF7 other 1 1 1 1.92327078859601 -1.14271284197555 0.907856537195906 -43.7574283799343 101.244995444601 -0.43219349448119 0.666247282756749 -40.8990015294987 149.601708420212 -0.273385925611348 0.784948281238008 GADD45B other 1 1 1 -0.43219349448119 -0.273385925611348 0.00015134352650936 761.294257313798 177.205932243214 4.29609916370591 3.2456323841116e-05 393.674499458238 264.475403485999 1.48851081903757 0.138881492155159 PALM other 1 1 0.313365806685975 4.29609916370591 1.48851081903757 0.0157621201236777 151.594843970326 71.6177064993443 2.11672296391835 0.0359227395623136 353.610538900128 122.852095886008 2.87834355897548 0.00457802427850244 IGF2-AS other 1 1 1 2.11672296391835 2.87834355897548 0.101220201233391 416.4585054099 374.858744325871 1.11097449829759 0.26848369508719 -650.036028628558 563.439416170804 -1.15369285494131 0.250591868372518 MKNK2 other 1 1 1 1.11097449829759 -1.15369285494131 3.74363852864342e-10 297.072312983663 47.7669087057089 6.21920741854827 5.34057712996156e-09 34.6223559759244 75.4502973835694 0.458876335502211 0.647029549195957 ARVCF other 4.31941013434877e-06 1 6.57371638926968e-05 6.21920741854827 0.458876335502211 1.00834892831439e-09 135.650857847374 42.3388838968807 3.20393088721377 0.00167888634174818 -227.030972380656 65.2442105637254 -3.47971061982442 0.000669519012461032 TRMT2A other 1.13822427028128e-05 1 1 3.20393088721377 -3.47971061982442 1.06504211980943e-05 336.34112251835 172.031421434228 1.95511447684539 0.0525615055364517 -748.535759964049 265.100381742909 -2.82359367060425 0.00544185585734806 RANBP1 other 0.0877594706722972 1 1 1.95511447684539 -2.82359367060425 6.31202609137672e-13 510.662933388641 69.7834037210091 7.31782782379388 1.78977590465774e-11 64.0062912648205 107.536209440854 0.595206875875836 0.552666070511475 ZDHHC8 other 8.06171972390635e-09 1 2.37467467029989e-07 7.31782782379388 0.595206875875836 3.71515779249547e-11 200.583284883721 37.2217982573584 5.38886604824546 2.95497552744032e-07 -94.6724736987818 61.1575066655409 -1.54801068357034 0.123893531672751 KLHL22 other 4.47453604528154e-07 1 0.00333794035579659 5.38886604824546 -1.54801068357034 2.50220555280726e-13 597.002539503386 116.130741658204 5.14077952985511 8.96709904795718e-07 -548.128668171557 190.776827351786 -2.87314070466655 0.00469309150124842 MED15 other 3.2313482508953e-09 1 0.00982345700703709 5.14077952985511 -2.87314070466655 6.90944822358553e-13 265.652063524962 45.766580870436 5.80449879524573 3.99884920676591e-08 -137.914350112697 74.6140949890452 -1.84836859755446 0.0666145185949647 SNAP29 other 8.81161931953863e-09 1 0.000474023584970031 5.80449879524573 -1.84836859755446 2.38762005399649e-14 783.669227439949 98.9159123180317 7.92257998814506 6.33365024550378e-13 145.467106686864 163.238357692623 0.891133118116624 0.374375876414823 CRKL other 3.16264152352375e-10 1 8.62896509447435e-09 7.92257998814506 0.891133118116624 3.75743083263049e-09 336.74552862558 54.6410625165104 6.16286567494599 7.07332298280838e-09 100.572761610032 89.8869595336954 1.11888044864095 0.265093661406568 LZTR1 other 4.10987784473123e-05 1 8.66835731543167e-05 6.16286567494599 1.11888044864095 0.17632833268484 336.402838007428 268.53442328345 1.25273636762889 0.212225528787399 -1861.3764141888 1485.65939678019 -1.25289579712745 0.212167654149746 MMP11 other 1 1 1 1.25273636762889 -1.25289579712745 0.0406318930570579 84.9406650089049 33.6940707905514 2.52093804684248 0.0128254135631326 88.3635286803992 50.4625463989452 1.7510715369339 0.0821237775887663 CECR2 other 1 1 1 2.52093804684248 1.7510715369339 1.58755192732348e-69 1106.94738689595 33.8926373018159 32.660408720588 1.35121058745698e-70 305.978726593271 187.510094510139 1.63179869005253 0.104791995562418 SMARCB1 other 2.32020714178327e-65 1 1.97479427356838e-66 32.660408720588 1.63179869005253 6.21927152190686e-05 17.2938616466778 3.83948186789161 4.50421755896309 1.37931517677244e-05 10.2407772885988 6.90567651320812 1.48295062315933 0.140303558377538 P2RX6 other 0.468000182023491 1 0.138028069739618 4.50421755896309 1.48295062315933 0.000815414902016245 61.0514210375221 18.3868913982667 3.320377529574 0.0011255883649305 -162.789879958746 101.98219304288 -1.59625788680872 0.112508217997832 DERL3 other 1 1 1 3.320377529574 -1.59625788680872 2.38930986115629e-05 228.448144765103 48.4964146689251 4.71061925556086 5.78877047566767e-06 126.239296911645 87.232911778237 1.44715216239222 0.150042930935576 SLC7A4 other 0.189687309877198 1 0.0600179722917224 4.71061925556086 1.44715216239222 6.75806934723279e-18 304.590980879734 49.9351741545029 6.09972801811621 9.80723709368105e-09 -271.680449611883 74.7863343190232 -3.63275526318685 0.000392657889109703 BCL2L13 other 9.41061156602167e-14 1 0.000119432533326848 6.09972801811621 -3.63275526318685 8.68622922078284e-10 159.718046841195 29.0001076836834 5.50749840598208 1.53007433151206e-07 -576.705088242567 160.048830465194 -3.60330710675192 0.000425947586889946 DDTL other 9.83802321545864e-06 1 0.00176111555557038 5.50749840598208 -3.60330710675192 3.33783194705355e-34 32.2591072587625 1.9728335026566 16.3516623249365 3.10289562937149e-35 9.321654586759 10.8878800812314 0.856149637690055 0.393271582051523 GSTT2 other 4.85187251823704e-30 1 4.51409256160965e-31 16.3516623249365 0.856149637690055 0.572074913128093 -10.2362644584648 10.5878280765769 -0.966795492373943 0.335182019199945 0.199044865054325 19.621343550233 0.0101443035511175 0.991919457753757 OSM other 1 1 1 -0.966795492373943 0.0101443035511175 4.46043943232228e-70 1731.81980015788 52.480512854593 32.9992926127877 3.41179815118724e-71 650.002253616798 289.326790362804 2.24660237236145 0.0261061706009847 CABIN1 other 6.51937827428225e-66 1 4.98668417777527e-67 32.9992926127877 2.24660237236145 3.84524046931541e-05 153.441968980021 41.933923125687 3.65913698368061 0.00034843632998903 -92.6479582895195 77.7118693378126 -1.19219829710671 0.23504143795819 TBC1D10A other 0.296621849802991 1 1 3.65913698368061 -1.19219829710671 0.128363110984186 72.0283029332201 118.651765471057 0.607056310095868 0.544719275658015 -1223.96976129715 654.131078515492 -1.87113837195272 0.0632479881102444 SUSD2 other 1 1 1 0.607056310095868 -1.87113837195272 5.22055056014416e-09 1107.35127497371 168.449904730121 6.57377204663804 7.40507490055224e-10 712.072861899754 312.171054139588 2.28103423574099 0.0239356319058529 SF3A1 essential 5.66325324764438e-05 1 9.3837109139798e-06 6.57377204663804 2.28103423574099 0.460905043070947 2.6404039221806 13.044259516415 0.202418843235823 0.839859980259601 -86.4701805035371 71.9134309719976 -1.20242045657935 0.231070452581558 GGT5 other 1 1 1 0.202418843235823 -1.20242045657935 9.64673972079182e-08 146.584977308512 24.5087907377667 5.98091431261979 1.52537555570119e-08 86.5726652465193 46.5465020471318 1.85991774760772 0.0648297439725486 RNF215 other 0.000961008210985281 1 0.000184143337084247 5.98091431261979 1.85991774760772 0.000273566856791877 70.0536765563943 24.4362811023059 2.86678960121242 0.00473140020863435 -77.5346288032134 46.061981883068 -1.68326732010883 0.0943627179697117 SEC14L2 other 1 1 1 2.86678960121242 -1.68326732010883 1.91461279378558e-88 1031.37112846074 22.9724243332396 44.8960507389031 1.29042647078995e-89 664.542855438052 126.64772956019 5.24717543493128 5.10785180010607e-07 SPECC1L other 2.80031267219079e-84 0.00745695284297485 1.88737775617737e-85 44.8960507389031 5.24717543493128 2.81120221181307e-12 367.617040271431 55.5615480219567 6.61639305165071 6.01594566207117e-10 -78.0290322179737 103.930589445008 -0.75078023356406 0.453953308159719 PPIL2 other 3.52131189051705e-08 1 7.64807172019108e-06 6.61639305165071 -0.75078023356406 5.96671065472705e-11 185.289205715304 26.9440272649314 6.87681926288963 1.51634851871134e-10 41.4179968266724 50.4001190636386 0.821783709962575 0.412495677287236 YPEL1 other 7.12663920600599e-07 1 1.96503604539802e-06 6.87681926288963 0.821783709962575 1.84277194294171e-41 585.882240489824 31.1311149015275 18.819828404574 1.51073392633512e-41 -335.538357384154 171.626858522331 -1.95504573277787 0.0524120732298627 SNRPD3 essential 2.68473444367178e-37 1 2.2012904040629e-37 18.819828404574 -1.95504573277787 2.66792591164065e-08 456.744655080137 80.8243187590367 5.65107955245302 7.58089333922085e-08 -47.5288724261284 152.352491396031 -0.3119664929048 0.755490717440717 PES1 essential 0.000276877351110067 1 0.000886130622421525 5.65107955245302 -0.3119664929048 6.18420195765420e-12 687.732498021848 113.531243189454 6.05764967159045 1.05250079076722e-08 -311.938600670293 212.365735750228 -1.46887443762197 0.143947067923059 MAPK1 other 7.65604202357591e-08 1 0.000127952521133571 6.05764967159045 -1.46887443762197 0.00331239346648639 66.6001881467545 24.1260178373423 2.76051309402874 0.00648658117458089 -21.4425211665099 45.4679803265784 -0.471596077338312 0.637895829082408 PPM1F other 1 1 1 2.76051309402874 -0.471596077338312 4.18380340835236e-08 133.665562519835 22.0746696394119 6.05515573746978 1.0414545165348e-08 45.6310937444905 40.0025898161144 1.14070348830537 0.255775731694639 SLC35E4 other 0.000427961250640362 1 0.000126640869210631 6.05515573746978 1.14070348830537 2.77714563552021e-07 114.14489194499 22.6611405370657 5.03703208398929 1.32421508297125e-06 0.591683038637739 45.7732601526025 0.0129263905753084 0.989703470532749 TOP3B other 0.00265772837319285 1 0.0143571399295743 5.03703208398929 0.0129263905753084 0.932456241801636 7.03046057140153 25.989088856907 0.270515854176745 0.787123294923159 -4.7655882978472 51.6855272317984 -0.0922035345886011 0.926655391273942 CYTH4 other 1 1 1 0.270515854176745 -0.0922035345886011 0.0148091537059088 15.7505698473851 6.46156031270142 2.43757994743535 0.015939629052514 -48.3730811429868 35.9261367931116 -1.34645930403131 0.18015883895208 CRYBB2P1 other 1 1 1 2.43757994743535 -1.34645930403131 0.181892457782314 68.0380937600725 37.8214923446127 1.79892673562797 0.0739885027758357 96.2911361275922 75.1646629646248 1.28106921962665 0.202095129902362 MFNG other 1 1 1 1.79892673562797 1.28106921962665 7.17891603173361e-09 265.126650988085 42.4381392419609 6.24736747943793 3.89289029060256e-09 112.452940848649 86.2435977573331 1.30389899972705 0.194213682894034 CARD10 other 7.7209241921295e-05 1 4.81511600044631e-05 6.24736747943793 1.30389899972705 9.16588272419093e-42 36.5712115348408 1.89554028860057 19.2932916038627 8.02778219131899e-43 14.0448686723188 10.5235863484781 1.33460858373154 0.183987209421094 LRP5L other 1.33556077174186e-37 1 1.17004925438474e-38 19.2932916038627 1.33460858373154 2.26025895014415e-12 763.075500211569 187.853384127771 4.06208013635012 8.01059932597568e-05 -1077.2065028393 299.478020245759 -3.5969467874648 0.000443608789030758 SLC25A1 other 2.83911126727606e-08 1 0.740579907686452 4.06208013635012 -3.5969467874648 0.0435035809798598 105.336635389371 42.2229661907189 2.49477109006436 0.0136875647165084 72.3999988931658 73.1658005217395 0.989533339031177 0.323995788947991 GRK3 other 1 1 1 2.49477109006436 0.989533339031177 0.605493447332448 2.5508197817631 3.40660206676976 0.748787129158839 0.455127651851027 -1.64061570013032 6.92296183606696 -0.236981762860964 0.812985886387137 LGALS2 other 1 1 1 0.748787129158839 -0.236981762860964 2.7179329081323e-18 740.741125068269 72.359931799568 10.2368963961999 4.37924164860286e-19 543.658874931731 147.051236537242 3.69707108715162 0.000302754085855976 GGA1 other 3.79994199885977e-14 1 6.25180537754544e-15 10.2368963961999 3.69707108715162 1.10376231963828e-13 399.46617904854 55.2421293454546 7.2311872076924 2.72073311362012e-11 5.73539545782658 88.0676364035283 0.0651248936845181 0.948166154607186 HIRA other 1.43787117379279e-09 1 3.59735332282853e-07 7.2311872076924 0.0651248936845181 1.98691628967585e-13 735.242737726875 87.1527736620669 8.43625173167482 2.30069699897054e-14 670.07679305408 176.006494253534 3.80711402664976 0.000202986149367903 SH3BP1 other 2.57285790350126e-09 1 3.18692548297399e-10 8.43625173167482 3.80711402664976 0.702617780844656 -4.52733015636908 6.22418107196494 -0.727377642781178 0.468128412651224 -0.458667327769047 10.4283230389051 -0.0439828461448584 0.964976573385768 SEZ6L other 1 1 1 -0.727377642781178 -0.0439828461448584 0.00585742288832421 695.322264813187 662.01958108345 1.05030468083019 0.295234188348958 -2945.91676903893 1336.95969385317 -2.2034447130928 0.0290580349021703 LGALS1 other 1 1 1 1.05030468083019 -2.2034447130928 5.74554193226868e-13 276.061877347143 40.2130451218421 6.86498315436444 1.64422201973871e-10 -7.43676831115854 67.3750683117981 -0.110378638530542 0.912256636851949 HPS4 other 7.34797357717841e-09 1 2.12844540455176e-06 6.86498315436444 -0.110378638530542 4.54385703596194e-08 424.773210097945 74.6940079279949 5.68684452583435 6.50000632592164e-08 50.055305433979 120.732029019887 0.414598394811488 0.679024327147639 PIK3IP1 other 0.000463564294808838 1 0.000763100742663201 5.68684452583435 0.414598394811488 4.03348139484724e-11 170.477023968965 23.3493629910044 7.30114239239176 1.45771932903968e-11 94.9600447974873 47.154431814585 2.0138095433082 0.045782395861069 NOL12 essential 4.85187476986174e-07 1 1.93745476022664e-07 7.30114239239176 2.0138095433082 7.13956719897856e-16 185.774607793522 25.5566666043464 7.26912514333647 1.89313539092983e-11 -37.1904099190286 38.6037793143925 -0.9633877972451 0.336913861042304 SRRD other 9.71980678468941e-12 1 2.51086546899023e-07 7.26912514333647 -0.9633877972451 2.29247579613807e-18 1093.19422707633 109.337601870424 9.99833733660885 2.11293612956421e-18 331.738358137302 178.382970911566 1.85969746126587 0.0648611243745205 PATZ1 other 3.20763213395639e-14 1 3.00839846127352e-14 9.99833733660885 1.85969746126587 1.3931100259977e-17 1163.97547683924 119.151110241738 9.76890164495928 8.08820528986896e-18 625.640871934601 240.62767389803 2.60003706888563 0.0102346039467982 TRIOBP other 1.93391533809001e-13 1 1.148039858844e-13 9.76890164495928 2.60003706888563 1.03391512810438e-13 271.866906787702 39.6007559978393 6.86519486654586 1.67213486626177e-10 -27.9286200025307 59.8176150626664 -0.466896247422636 0.641256105901695 TFIP11 essential 1.34843211007373e-09 1 2.16407694391598e-06 6.86519486654586 -0.466896247422636 8.04830811325963e-13 249.099709047246 33.1349837144771 7.51772541051261 4.38401059344756e-12 49.8699764466822 66.9166576768561 0.745255040792784 0.457260869884421 GCAT other 1.02471058898022e-08 1 5.88860302911876e-08 7.51772541051261 0.745255040792784 0.596584740668222 -5.84368367950454 6.41647644331719 -0.910730948851341 0.363898349679309 -1.22042468311122 9.62810902750946 -0.126756425340035 0.899302940249123 CRYBB1 other 1 1 1 -0.910730948851341 -0.126756425340035 1.31869740376363e-13 3130.44414168938 448.052082901379 6.98678627140413 8.10267004285562e-11 -822.773569482281 904.848727594647 -0.909294055890927 0.364625083642479 EIF3L essential 1.7154934525561e-09 1 1.05861384109909e-06 6.98678627140413 -0.909294055890927 1.1433374104114e-05 467.245803783741 214.359388846758 2.17973099427787 0.0307963644748765 -725.051330864769 315.115592656059 -2.30090591440883 0.0227384587623082 SNU13 other 0.0939480350135051 1 1 2.17973099427787 -2.30090591440883 7.70385584878403e-15 657.665770368379 73.8821613037767 8.90155023570975 1.54626978739201e-15 462.696952196126 149.298249420051 3.09914519422345 0.00231287377953497 MICALL1 other 1.02992848842394e-10 1 2.16524158328503e-11 8.90155023570975 3.09914519422345 2.05961517798452e-08 477.331271847271 85.2602228821033 5.59852244941136 9.84138664466116e-08 25.0708161380451 172.290601639596 0.145514705384157 0.884497294046189 POLR2F essential 0.000215394555313621 1 0.00114396278357541 5.59852244941136 0.145514705384157 8.34584479964388e-07 26.5376026694045 5.332163810567 4.97689186082649 1.71121862466497e-06 7.63789071412269 7.92671200069144 0.963563544816117 0.336775390672003 CCDC134 other 0.00766398927951297 1 0.0184281133690171 4.97689186082649 0.963563544816117 3.73534111416936e-14 149.849555273189 17.4449248789314 8.58986532261685 9.36180837105661e-15 63.9435408725116 30.6374682792193 2.08710263817337 0.0385370310904245 DEPDC5 other 4.9272884637008e-10 1 1.30260201674882e-10 8.58986532261685 2.08710263817337 1.80973099094124e-16 219.9854686549 24.0360447205737 9.1523156664209 3.79710539282337e-16 83.6219567863663 48.7520601753541 1.71524970402461 0.0883643963553925 PICK1 other 2.48150313477863e-12 1 5.34138815608463e-12 9.1523156664209 1.71524970402461 2.11586767492466e-07 671.729869902369 115.33316417456 5.82425596930375 3.51644589511113e-08 410.649584119266 194.957182769468 2.10635780783132 0.0368839927595766 TTC28 other 0.00204985260346701 1 0.000418035088010811 5.82425596930375 2.10635780783132 0.0466649224775087 19.0812603648424 7.65305689624704 2.49328609776828 0.0137575070318398 20.7668877833057 15.4487132743651 1.34424708482132 0.180925357730439 SLC16A8 other 1 1 1 2.49328609776828 1.34424708482132 1.04777641818118e-05 121.162812964445 31.5569241079925 3.83950009037027 0.000179227396163605 -11.7234623299418 46.9241425783137 -0.249838605156739 0.803042974664507 CENPM other 0.086444113063495 1 1 3.83950009037027 -0.249838605156739 0.015608153434588 102.003186806905 39.7588360677423 2.56554760891665 0.0112497759304056 23.7719360923747 59.1201248260449 0.402095498991608 0.68816767319475 SEPT3 other 1 1 1 2.56554760891665 0.402095498991608 0.0201294345245267 128.975682412842 92.3406844117067 1.39673734534819 0.16450218910255 -362.900060108903 211.416655130782 -1.71651594754639 0.0880783165283981 SLC5A1 other 1 1 1 1.39673734534819 -1.71651594754639 0.38049366033486 48.189556203895 35.6428603608796 1.35201147483624 0.178506118376998 24.7021988187575 53.6277257010312 0.460623651214852 0.64576836179766 TPTEP1 other 1 1 1 1.35201147483624 0.460623651214852 0.000392350823281919 87.6370301320164 74.5311931688298 1.17584364889341 0.241532709200758 -440.709359288746 150.956853831496 -2.9194392179151 0.00405140177787554 KDELR3 other 1 1 1 1.17584364889341 -2.9194392179151 0.0109784001106513 69.8761503944209 23.00809428798 3.03702468878207 0.00280402061897097 69.0538827598035 34.2123045050204 2.01839319972352 0.0452748932649136 CYP2D6 other 1 1 1 3.03702468878207 2.01839319972352 2.99900391396426e-13 3183.24428096342 398.275639086282 7.99256587288734 3.35499025219434e-13 1126.42465876135 806.674828054916 1.39638007730752 0.164676818599998 DDX17 other 3.86361674236016e-09 1 4.58593617572444e-09 7.99256587288734 1.39638007730752 0.275685355248619 3.74138365413687 5.23601161545072 0.714548387000628 0.476006128946592 -10.1390848421736 10.6051145364485 -0.956056137567093 0.34059247383076 DMC1 other 1 1 1 0.714548387000628 -0.956056137567093 8.20103097352653e-08 553.09696181548 93.4313300161018 5.91982327255921 2.0006173010971e-08 363.720118326284 138.929416439755 2.61802091772268 0.00972114495166503 TCF20 other 0.000821825313857093 1 0.000240434187245849 5.91982327255921 2.61802091772268 2.35415429132505e-08 62.1225931834012 20.3909533895156 3.04657619468361 0.00275711074322258 -120.886753240918 32.7086057323119 -3.6958699563735 0.000311380394545397 HSCB essential 0.000245067461726938 1 1 3.04657619468361 -3.6958699563735 1.46897157937665e-07 312.4598615155 56.7964915267559 5.50139371493229 1.58822310917548e-07 67.3829066520954 113.882529643229 0.591687828354291 0.554950348545743 CBY1 other 0.00144179560515819 1 0.00182533778863654 5.50139371493229 0.591687828354291 1.37605259952844e-10 764.437498470798 124.627623548092 6.13377256749033 7.27296064360985e-09 -167.488115724542 249.890594499041 -0.670245777198248 0.503731695622049 TOMM22 essential 1.61906348860516e-06 1 8.90719490022898e-05 6.13377256749033 -0.670245777198248 1.98158516465547e-12 11.1454456303097 1.38666134690551 8.0376118186189 2.310402979082e-13 8.0024792994766 7.64352677108207 1.04696163683924 0.296768414946892 RSPH14 other 2.49283413713658e-08 1 3.16386583955489e-09 8.0376118186189 1.04696163683924 0.000646546087545939 1327.02337033997 717.182710330283 1.85032816773962 0.0663444321540628 -2619.46559246619 1138.53040003838 -2.30074277540406 0.0228624232974296 XBP1 other 1 1 1 1.85032816773962 -2.30074277540406 4.34580991690823e-26 551.694188233336 46.2000381983768 11.9414227725188 1.21478720954408e-23 -3.48006823666413 101.928032022943 -0.0341424058484793 0.972808094993411 RTCB essential 6.27274203406533e-22 1 1.75208759232542e-19 11.9414227725188 -0.0341424058484793 1.14657496740905e-20 707.290352572728 65.3037603194006 10.830775274094 1.47796175320434e-20 295.397739228304 130.940436996624 2.25597031752628 0.02551841723603 JOSD1 other 1.62561398879256e-16 1 2.1199883387963e-16 10.830775274094 2.25597031752628 1.67917225252225e-32 1011.69350253807 69.889814525891 14.4755499696352 1.83624198701883e-30 127.38345177665 154.193189678421 0.826128910377404 0.410017361444829 FBXO7 other 2.43849394511282e-28 1 2.66512161995913e-26 14.4755499696352 0.826128910377404 2.92388737833994e-15 872.760857331604 95.7439563294439 9.11557126727179 4.72280098932958e-16 612.066088696415 191.976012104752 3.18824254127354 0.00174252703102608 GTPBP1 other 3.9375991324104e-11 1 6.6374245104038e-12 9.11557126727179 3.18824254127354 5.14776081332558e-09 522.317160096052 99.0462001362229 5.27346995016149 4.43124214722916e-07 -0.136235143925006 150.591966674315 -0.000904664086230052 0.999279345867156 POLDIP3 other 5.58532048245826e-05 1 0.00495501496903165 5.27346995016149 -0.000904664086230052 1.24982671627656e-33 281.671800333604 17.4735259020111 16.1199177494672 1.01971868843887e-34 184.138259624921 96.1592935751994 1.91492941325447 0.0573797718897021 RAB36 other 1.81612320142147e-29 1 1.48318083233433e-30 16.1199177494672 1.91492941325447 0.174935939376324 1651.17786267573 915.246958862372 1.80407904848774 0.0731989642367824 573.391772642982 1498.13064282404 0.382738164651725 0.702448593234326 TIMP3 other 1 1 1 1.80407904848774 0.382738164651725 4.7572780022772e-07 303.318166478536 95.4953674576513 3.17626053026129 0.00182541077903605 -262.160078200459 151.604320356789 -1.72923883424619 0.0859093635536154 PPP6R2 other 0.00446185103833579 1 1 3.17626053026129 -1.72923883424619 0.000644933995349487 635.099985937281 186.008787415086 3.41435474508003 0.000836629886486502 174.905357896218 298.209154202091 0.586519077069269 0.558471264178996 SBF1 other 1 1 1 3.41435474508003 0.586519077069269 4.64268468780037e-06 845.557583616744 165.516387581029 5.10860341972361 9.72576039859326e-07 552.707945595762 331.876572098773 1.66540211651718 0.0979197601777329 SUN2 other 0.0395835296481859 1 0.0106370641479415 5.10860341972361 1.66540211651718 7.91910680984669e-11 1590.48594182194 312.62112406948 5.08758308177682 1.03588548753759e-06 -584.065169154077 475.315861010409 -1.22879377076223 0.221011472782981 CYB5R3 other 9.41344226486476e-07 1 0.011312905409398 5.08758308177682 -1.22879377076223 1.79683916582544e-05 230.063981796384 56.8957802276953 4.04360360075341 8.3902158928067e-05 -59.5714184738432 114.081613215542 -0.522182469152948 0.60231358767131 DNAL4 other 0.144483837324024 1 0.773494003157849 4.04360360075341 -0.522182469152948 7.31729059792494e-05 277.335912212836 161.326912515766 1.71909266648696 0.0878236227169174 -560.795900107893 257.771445637087 -2.17555477769027 0.0312791550063921 LMF2 other 0.546674780570972 1 1 1.71909266648696 -2.17555477769027 4.34629236828457e-07 123.509475945676 25.7174914578534 4.80254756371114 3.88587774363606e-06 -29.4625949512774 40.925784412628 -0.719902999395816 0.472751565174675 RHBDD3 other 0.00409377278168723 1 0.0408376789989888 4.80254756371114 -0.719902999395816 1.27969579579569e-10 334.712452807023 79.0407968650209 4.2346796348551 3.92248864090081e-05 -266.954710089319 120.056493730251 -2.22357576666471 0.0276325956917309 PACSIN2 other 1.50773758660648e-06 1 0.374754564751663 4.2346796348551 -2.22357576666471 4.6572597950693e-17 114.288682893888 14.536050136578 7.86243042780215 6.11863418802819e-13 -1.3831609318887 22.0790690542367 -0.062645799444306 0.950129793434114 TTLL1 other 6.42841569513416e-13 1 8.33786280802602e-09 7.86243042780215 -0.062645799444306 0.0331609386031743 6.85643159693838 2.59595506886587 2.64119810052562 0.00917364946234392 4.44782853321162 4.16499100544181 1.06790831658466 0.287348875976461 RASL10A other 1 1 1 2.64119810052562 1.06790831658466 2.16115494269225e-07 669.072279326694 160.775688112754 4.16152645453128 5.43282236859576e-05 -544.899505788098 266.716178976014 -2.04299382167252 0.0428896412401827 AP1B1 other 0.00209113352254902 1 0.511717538898035 4.16152645453128 -2.04299382167252 1.34402383626884e-08 201.431234801406 34.4295491310431 5.85053362257908 2.90373287502812e-08 26.309227235882 57.4189957963015 0.458197272018064 0.647465109865747 HMGXB4 other 0.000142278363307419 1 0.000346328220004604 5.85053362257908 0.458197272018064 4.08384441997005e-06 141.112807349365 48.6982413358942 2.89769822232482 0.00431510898576277 -198.542150770062 81.2152405455642 -2.44464154063145 0.0156427921566234 TOM1 other 0.0351006427896426 1 1 2.89769822232482 -2.44464154063145 0.0655321756617451 159.209942206216 81.137761922785 1.96221757210568 0.0516786000911735 292.556223301785 149.896468542672 1.95172191944269 0.0529253585137175 NEFH other 1 1 1 1.96221757210568 1.95172191944269 0.00264435941150342 69.9717950422007 66.1388887256348 1.05795238460183 0.291925531419624 -206.314693958929 105.584481433065 -1.95402478810035 0.0527205319374146 CHKB other 1 1 1 1.05795238460183 -1.95402478810035 2.91515814299869e-05 -46.0144878602786 62.6128692996514 -0.734904635021012 0.463515211305625 -398.189861567267 95.1038178846255 -4.18689670324622 4.74134565381117e-05 BIK other 0.228985672132547 0.68246929340958 1 -0.734904635021012 -4.18689670324622 0.97460153377669 22.0431889627453 104.473252589326 0.210993612397566 0.833176732715527 5.05659173156438 176.126698916916 0.0287099671012953 0.977133816877095 HMOX1 other 1 1 1 0.210993612397566 0.0287099671012953 4.88745205087163e-09 158.815742002567 36.6645441613267 4.33158915882784 2.65801436022505e-05 -79.8405239982046 56.3835222636679 -1.41602583153362 0.158787325644135 MCAT other 5.31070539847711e-05 1 0.259076659691136 4.33158915882784 -1.41602583153362 0.0384599920764921 337.941999259322 132.616248523698 2.54826993691449 0.0118382087422834 145.082324397723 241.809479317713 0.599986091558882 0.549426884893185 THOC5 essential 1 1 1 2.54826993691449 0.599986091558882 5.44759885600161e-06 510.906758602004 124.35960970474 4.10830139958642 6.53293942591217e-05 -131.107398916884 207.500662556847 -0.631840868850071 0.528452655540371 MCM5 essential 0.0461520575080457 1 0.610111212985938 4.10830139958642 -0.631840868850071 0.749042840560874 -0.847081684908933 2.30352895757675 -0.367732162481708 0.713587887894819 -3.51204043180221 4.6174846596083 -0.760596015082405 0.448084440506456 APOBEC3H other 1 1 1 -0.367732162481708 -0.760596015082405 0.0004383077999684 301.022502824483 97.6106669563885 3.08390990668035 0.00246818941794049 -16.796052369244 155.826199252896 -0.107787088755114 0.914321137843892 ARSA other 1 1 1 3.08390990668035 -0.107787088755114 7.74922534799906e-08 334.942637478631 374.482840164584 0.894413846389929 0.372496236271737 -2458.60453575114 575.887742197894 -4.26924269366769 3.41659345450216e-05 TSPO other 0.000778099717192585 0.492911937681026 1 0.894413846389929 -4.26924269366769 0.145074465316632 -7.1366384157087 17.7987567714259 -0.400962747418733 0.689010625740579 -58.0287454896367 30.9575539152573 -1.87446158209023 0.0627857489297365 RASD2 other 1 1 1 -0.400962747418733 -1.87446158209023 0.000221242395002746 355.569907126596 210.621246281058 1.68819581787165 0.0933976958138139 -680.760923850109 323.897869195813 -2.10177648139622 0.037200495074633 TTLL12 other 1 1 1 1.68819581787165 -2.10177648139622 2.41771032382246e-09 186.287589543764 29.8964446765049 6.23109508704105 4.39274586347638e-09 35.8425321442602 59.982608146048 0.597548743745677 0.551036128336462 CBX7 other 2.67350407608287e-05 1 5.42152694470254e-05 6.23109508704105 0.597548743745677 1.50673755205737e-10 451.246309780437 62.3236966684665 7.24036496392151 2.16813635592508e-11 297.84811351418 108.399912128492 2.74767855126235 0.00673815398938647 PDGFB other 1.76981392864658e-06 1 2.87169660342277e-07 7.24036496392151 2.74767855126235 0.000384303719219992 135.75171026548 39.7782982962829 3.41270783517064 0.000829759027417032 -53.2780639017375 73.2601740688627 -0.727244571541113 0.468224969163676 CABP7 other 1 1 1 3.41270783517064 -0.727244571541113 4.87132098663138e-11 12734.7606839842 2256.39358828424 5.64385608526203 8.06656445383648e-08 -7072.27551771417 3924.55646523064 -1.80205727204349 0.0735444439022331 RPL3 essential 5.83827820247771e-07 1 0.000941287406118179 5.64385608526203 -1.80205727204349 0.0156674600806051 135.742002565398 68.182299719274 1.99086864368445 0.0483364168677545 -150.971042095852 125.572167734389 -1.2022651581136 0.231180856574456 ZMAT5 essential 1 1 1 1.99086864368445 -1.2022651581136 3.41712889245475e-07 672.326526865222 117.794899693417 5.70760303387565 5.77086401154452e-08 495.121319720398 203.4028707764 2.43419042135685 0.016076205629377 RBFOX2 other 0.00324558902205353 1 0.000679172985518675 5.70760303387565 2.43419042135685 0.0141189382222941 72.6621436336943 39.5067456366214 1.83923384381069 0.0678579441589244 -84.6381175116842 68.7142769831757 -1.23173991239706 0.219973743933372 SYNGR1 other 1 1 1 1.83923384381069 -1.23173991239706 6.75546060709826e-14 188.39182267519 25.6744053854624 7.33772875541893 1.27175679506369e-11 -33.0541120123136 44.6556195557562 -0.740200502000488 0.460335337161967 TAB1 other 8.85573330984511e-10 1 1.69270829422977e-07 7.33772875541893 -0.740200502000488 0.0302239575380891 335.932405643876 138.964576553975 2.41739595783532 0.0168482404122324 -31.4362926108763 255.932744832912 -0.122830287431176 0.902408129167255 ASCC2 other 1 1 1 2.41739595783532 -0.122830287431176 0.00495935900969684 513.226421433577 154.986485750473 3.31142692182768 0.00116466518953684 320.014255133289 285.773785734313 1.1198166910621 0.264593729233952 MTMR3 other 1 1 1 3.31142692182768 1.1198166910621 7.53410584941614e-18 364.042115763244 36.925564329542 9.85880980759975 5.49897765148916e-18 141.198649814883 64.224815641312 2.19850611332947 0.0294450958180498 MIEF1 other 1.04852151106324e-13 1 7.81349734500094e-14 9.85880980759975 2.19850611332947 6.59458557909981e-05 157.279986079962 59.4159584015834 2.64710004367733 0.00895701132675515 -215.00403101075 118.16286261041 -1.81955672248421 0.0707561357383928 APOL4 other 0.495055539423023 1 1 2.64710004367733 -1.81955672248421 0.0103911209204108 124.552780140744 524.161927495351 0.237622714675035 0.81248753795776 -2620.09075090867 1042.42152260882 -2.51346570852787 0.0129766988127869 APOL1 other 1 1 1 0.237622714675035 -2.51346570852787 8.82267167432622e-06 45.1944963277194 10.7665962417256 4.19765869482218 4.52950920807909e-05 4.25516810181077 16.812815565313 0.253090750046038 0.80053344500211 PNPLA3 other 0.0733075789419766 1 0.430484555135836 4.19765869482218 0.253090750046038 2.74608749911348e-08 6937.22070942316 1294.93245295807 5.35720661998715 3.00367938767333e-07 -274.617475815113 2593.77144847653 -0.10587574166429 0.915817838879193 MYH9 other 0.000284659430158103 1 0.00339235550043825 5.35720661998715 -0.10587574166429 0.0151106980360512 10.292101753298 3.76266247991435 2.73532420413437 0.00698360525289835 14.3605636854749 6.54441735639626 2.1943227186511 0.0297504443601031 CACNA1I other 1 1 1 2.73532420413437 2.1943227186511 1.7037273890304e-06 304.991436621502 91.0784760555581 3.34866644491786 0.00101948693033527 -204.937745346335 142.225600878151 -1.44093429087996 0.151620324075438 SAMM50 essential 0.0152193967662085 1 1 3.34866644491786 -1.44093429087996 2.94032713721248e-11 448.453374568632 102.325674797905 4.38260852375844 2.15241150670101e-05 -641.125094288032 204.960044927915 -3.12804914984049 0.00210245977833897 TXN2 other 3.55485550888988e-07 1 0.211582051108709 4.38260852375844 -3.12804914984049 3.77307129751013e-13 712.842576703313 87.8997581732245 8.10972170479139 1.44032813926203e-13 431.646547172302 176.064691680937 2.45163606087771 0.0153314075324848 FOXRED2 other 4.85066046007903e-09 1 1.97641827269536e-09 8.10972170479139 2.45163606087771 0.64587836693734 2.25054336576277 3.88090396425983 0.579901844129245 0.562845083969976 -2.63654375018485 6.75653274697773 -0.390221412212382 0.696922742715049 GRAP2 other 1 1 1 0.579901844129245 -0.390221412212382 2.21268935599075e-17 1526.93529955307 241.457476250743 6.32382696639893 2.59764042311707e-09 -1694.16608129514 483.643379613915 -3.50292416417975 0.000601542879219804 EIF3D essential 3.06545983378958e-13 1 3.23328303465382e-05 6.32382696639893 -3.50292416417975 4.76396886244967e-09 492.819346140883 75.3351284682615 6.54169384404125 8.75605600285107e-10 303.563548236956 125.31563628959 2.42239162825185 0.0165950796430036 TNRC6B other 5.17986334414153e-05 1 1.10772864492069e-05 6.54169384404125 2.42239162825185 0.000774454614850275 230.052762587954 77.4162349770532 2.97163460165872 0.00344467561939831 -83.8323631445877 129.145214966639 -0.649132553352776 0.517232333347161 SGSM3 other 1 1 1 2.97163460165872 -0.649132553352776 2.88924798654544e-14 247.505647853062 29.0212691217438 8.52842261359347 1.25388231171512e-14 146.968793018914 58.1300893915972 2.52827398954867 0.012463066245057 IFT27 other 3.8181412142198e-10 1 1.74189330743464e-10 8.52842261359347 2.52827398954867 0.711442176720511 -1.54102472232176 7.06147605927015 -0.218229830333949 0.827537096253368 -11.3025349337156 14.1442551268183 -0.799090148783115 0.425460935876372 PVALB other 1 1 1 -0.218229830333949 -0.799090148783115 0.035436140399336 95.2777799976019 97.5310644538661 0.976896751113282 0.330152347328906 -211.195708634676 152.149030529077 -1.3880844846679 0.167116158997074 KIAA0930 other 1 1 1 0.976896751113282 -1.3880844846679 0.413962464351443 -3.91025665202061 11.0296899543039 -0.354520994535733 0.723430337850929 -28.4795960700749 22.0926541949508 -1.2890979878997 0.199284523708735 NCF4 other 1 1 1 -0.354520994535733 -1.2890979878997 0.657083445544278 10.0912142412642 15.9884777499945 0.631155410731186 0.528868531987557 -8.36710573459806 32.025189420348 -0.261266393299826 0.794233909666227 CSF2RB other 1 1 1 0.631155410731186 -0.261266393299826 1.7777585266837e-08 109.591137198674 31.9886642329546 3.42593665057678 0.000786866445124698 -100.025424705234 47.1582524566185 -2.12105876478881 0.0355287048722502 SLC25A17 other 0.000186842421154457 1 1 3.42593665057678 -2.12105876478881 0.0334337752646586 105.878571143165 45.552496221403 2.32431984909354 0.0214150133813025 25.4537339673153 71.0621603186163 0.358189701146015 0.720691859219243 FAM118A other 1 1 1 2.32431984909354 0.358189701146015 1.63720248571661e-05 89.478011201172 18.3899422484744 4.86559500797753 2.78209903461588e-06 90.5465321265686 36.5728043067624 2.47578860420682 0.0143697780923114 KCTD17 other 0.132187728696759 1 0.0295375454505168 4.86559500797753 2.47578860420682 7.9254629605218e-12 770.226274755803 195.376986651895 3.94225690525221 0.000122497610460742 -835.35305262888 288.028196289973 -2.90024748753378 0.00427827751706094 ST13 other 9.77685110809969e-08 1 1 3.94225690525221 -2.90024748753378 0.939880329337293 12.7482808327623 42.9106208441691 0.297089172376648 0.766796194344266 26.5151641184395 85.3380460694853 0.310707419957212 0.756440483109808 IL2RB other 1 1 1 0.297089172376648 0.310707419957212 0.000127645476571593 214.297780255961 127.566012873229 1.67989714054105 0.0950180797689107 -411.252004673143 186.731519314768 -2.20237058094037 0.029135321046175 RBX1 essential 0.923132086565761 1 1 1.67989714054105 -2.20237058094037 7.71982528634661e-08 227.492859515112 41.8162448134404 5.44029863346295 2.06640730316362e-07 72.4018598472268 62.5414354175134 1.1576622660463 0.248805908861935 L3MBTL2 other 0.00077530205350779 1 0.00235694416998843 5.44029863346295 1.1576622660463 1.79985979153718e-08 35.8170568000671 10.564494349526 3.39032381627182 0.000889619735569512 -35.6578572027856 15.78219241068 -2.25937285992378 0.0252818675627986 CHADL other 0.000189093269698896 1 1 3.39032381627182 -2.25937285992378 7.3330644330161e-07 931.768227200269 172.257215499646 5.40916805428209 2.41021052893054e-07 558.20190452219 257.33333079641 2.16917840683379 0.0316234476875519 RANGAP1 essential 0.00676035210079754 1 0.00273848120297088 5.40916805428209 2.16917840683379 2.26314950499082e-06 830.045977011495 167.861426429641 4.94482856881601 1.99538458655525e-06 346.091954022988 250.766505484729 1.38013628795439 0.169571191472528 ZC3H7B other 0.019979083830059 1 0.0214084812291513 4.94482856881601 1.38013628795439 0.000927706753473832 68.4557429314541 48.1153835352116 1.4227412919063 0.156860229191657 -143.079998322007 71.8790900674244 -1.9905649638552 0.0483216004079617 PHF5A essential 1 1 1 1.4227412919063 -1.9905649638552 5.87670829006259e-08 1030.59828844702 252.155664737987 4.08715104424843 7.04980043265242e-05 -444.328970551223 376.692824727232 -1.17955251967692 0.240021129536909 ACO2 essential 0.000595016714368838 1 0.655419946223696 4.08715104424843 -1.17955251967692 4.12526144554886e-11 717.012291299606 143.747163316545 4.98801002229643 1.64777996127223e-06 -320.760088933637 214.742449083987 -1.49369670645875 0.137327856891621 POLR3H essential 4.96021436212795e-07 1 0.0177614202025533 4.98801002229643 -1.49369670645875 0.0103701894007078 126.55314578714 44.8626247132261 2.82090373882718 0.00542856337341557 44.2876247228378 69.2604360511679 0.639436123245299 0.523501776665816 TRMU other 1 1 1 2.82090373882718 0.639436123245299 0.00146810367317107 25.9819494584837 50.7706058420337 0.511751810473235 0.609567396404268 -200.168947245837 75.3014160963489 -2.65823616105332 0.00869564052585303 PMM1 other 1 1 1 0.511751810473235 -2.65823616105332 3.46210599132917e-06 172.955776173285 74.8171835537491 2.31171193512025 0.0221365998590386 -270.675614300688 110.966567692077 -2.43925373137422 0.0158688221685122 DESI1 other 0.0299402926130146 1 1 2.31171193512025 -2.43925373137422 0.0267718886086246 278.659142876941 142.797223262051 1.95143250345678 0.0528441065266546 -94.0217052383591 220.455178742805 -0.426488984176008 0.670354975400982 CERK other 1 1 1 1.95143250345678 -0.426488984176008 5.10154682605317e-06 266.091411521689 55.1717445294025 4.82296533835143 3.40450488064461e-06 126.044489327519 89.3505259171384 1.41067428572731 0.160383970591365 BRD1 other 0.043368249568278 1 0.0359209309956813 4.82296533835143 1.41067428572731 6.68543290640525e-07 286.45840716089 52.6092244548032 5.44502242961189 2.03717340863685e-07 186.411714482442 85.20052996737 2.1879173117096 0.0302028122673604 ZBED4 other 0.00619004232804062 1 0.00232441485925464 5.44502242961189 2.1879173117096 0.681907145927485 -34.5882069438522 63.7511691950495 -0.542550158382635 0.588239421995385 24.2872819619259 103.149878715072 0.235456233826643 0.814173673701212 MLC1 other 1 1 1 -0.542550158382635 0.235456233826643 3.18660181483542e-05 136.873612658332 83.2960834192785 1.64321786859253 0.102504573134273 -353.772290299954 135.856241794624 -2.60401940777044 0.010172633906265 HDAC10 other 0.24900106581124 1 1 1.64321786859253 -2.60401940777044 9.07215566008588e-11 475.711066656101 70.5829658149977 6.7397432392253 3.04070907105625e-10 -98.0942930333276 175.073681426243 -0.560302909233413 0.576092342028265 ABHD4 other 1.07632054751259e-06 1 3.89910124181542e-06 6.7397432392253 -0.560302909233413 3.62278895171602e-12 637.553727059539 103.555694736323 6.15662642873383 6.64831171956624e-09 -325.649035713037 207.709923342969 -1.56780682632735 0.119061821864389 KHNYN other 4.52015377505608e-08 1 8.15814331107973e-05 6.15662642873383 -1.56780682632735 4.0478166737821e-07 91.4823862265433 76.2927002113348 1.19909750176796 0.232530175844605 -535.056277679621 115.481542369582 -4.63326230928964 8.19560614214021e-06 FKBP3 other 0.00382235328505244 0.119090352851439 1 1.19909750176796 -4.63326230928964 1.99353410500304e-14 389.892969830598 61.3824192527624 6.35186710750329 2.47265202022973e-09 -309.692972169993 122.749718751972 -2.52296278410021 0.0126936331135931 SDR39U1 other 2.64502105051803e-10 1 3.07944082599411e-05 6.35186710750329 -2.52296278410021 0.992982982998348 -0.676718367389871 5.70655315728801 -0.118586184819047 0.905759784451193 -0.633780552918054 11.189369378779 -0.0566413111823837 0.954905313842458 GZMH other 1 1 1 -0.118586184819047 -0.0566413111823837 0.815787107742127 -7.74589501664626 14.8025938059152 -0.52327957641795 0.601541729240184 -16.0348558419855 28.8426941893066 -0.55594167925999 0.579068146544273 GZMB other 1 1 1 -0.52327957641795 -0.55594167925999 2.495832326306e-14 491.927587621385 63.1749699055855 7.78674827002794 1.04488145934214e-12 -213.195346580734 151.828083900668 -1.40418914013441 0.162329681432329 RBM23 other 3.30423241679651e-10 1 1.41842658105695e-08 7.78674827002794 -1.40418914013441 4.5712577166554e-20 671.371137598902 74.8123311694172 8.97407054565029 1.09170999087306e-15 -570.29076573556 179.796095044765 -3.17187514886555 0.00183714284257211 PRMT5 essential 6.46055853094907e-16 1 1.53035906520586e-11 8.97407054565029 -3.17187514886555 0.092156797892996 34.7455305287611 26.514144409096 1.31045263964246 0.192006560903867 -43.467186000707 44.3817696560596 -0.979392807847903 0.328932022845361 COCH other 1 1 1 1.31045263964246 -0.979392807847903 1.50365985884982e-10 70.9925152994678 16.9359661209969 4.19181963356981 4.67962371548954e-05 -95.4873155533163 28.3791074964162 -3.36470467104628 0.000970084610819767 AP4S1 other 1.76664996816265e-06 1 0.444096290599957 4.19181963356981 -3.36470467104628 0.000791598020476805 33.4473298564088 15.1504172564836 2.20768374165372 0.0288054036025172 -46.7388650171262 24.41752806859 -1.91415219779146 0.0575306721261669 POLE2 other 1 1 1 2.20768374165372 -1.91415219779146 1.25384822947706e-08 59.7296832994559 10.9047848190731 5.47738302868527 1.72123199106852e-07 -11.320333092912 17.8774996962901 -0.633216796824286 0.527531304725759 VCPKMT other 0.000132970604736043 1 0.00197390884735738 5.47738302868527 -0.633216796824286 7.64907540265826e-08 327.908449282015 56.3905484774092 5.81495406829354 3.38855597087275e-08 94.8897147728014 92.4476759518674 1.02641536194166 0.306305352042802 SOS2 other 0.000768655587213128 1 0.000403068732735313 5.81495406829354 1.02641536194166 0.010060591617756 35.8469380869078 12.7387464363984 2.81400829083799 0.00552748446858198 1.77316355293006 20.8561424845344 0.085018768655082 0.932356184645015 CDKL1 other 1 1 1 2.81400829083799 0.085018768655082 0.000595307649312208 117.758021665653 29.8355318975171 3.94690539019528 0.000119158758842932 81.3817855833508 48.4365390637771 1.68017342189115 0.0949122470129475 NIN other 1 1 1 3.94690539019528 1.68017342189115 0.00634401032164776 269.544632050502 100.703802598036 2.67660828187791 0.00822696784242518 -80.9755495512686 163.487739557162 -0.495300441308972 0.621080577898671 PYGL other 1 1 1 2.67660828187791 -0.495300441308972 0.890998342418782 2.1340995495111 25.694801627709 0.083055692759648 0.933913056496807 -16.3702471411281 41.7142642890206 -0.39243763302897 0.695267143070448 TRIM9 other 1 1 1 0.083055692759648 -0.39243763302897 1.67160738213611e-07 224.93712800669 60.2867824134416 3.73111848073248 0.000265951218748765 -241.570884367126 93.117861716066 -2.59424862121213 0.010377082806478 PSMC6 essential 0.00163366189456162 1 1 3.73111848073248 -2.59424862121213 0.00205555395376233 143.057371001328 69.5592275878287 2.05662679075465 0.0413772049238479 -196.517749102297 107.439910977163 -1.82909448932871 0.0692827797138178 GNPNAT1 other 1 1 1 2.05662679075465 -1.82909448932871 0.00127762249892064 96.767825923236 25.9553017426281 3.72824892897731 0.000268746321663092 60.0066354662579 40.1472849838078 1.49466235364259 0.137009799009211 DDHD1 other 1 1 1 3.72824892897731 1.49466235364259 0.0667086899986869 -40.6379680288535 50.4583602554793 -0.805376310746059 0.421820614063197 -170.19763425742 73.3231426298605 -2.32119939425657 0.0215620967154341 CDKN3 other 1 1 1 -0.805376310746059 -2.32119939425657 7.03384304961017e-05 40.4937310878142 178.504923880412 0.226849378759673 0.820835969450226 -997.578598282239 259.392931667742 -3.84582028457138 0.000174273531338151 CNIH1 other 0.526272136971833 1 1 0.226849378759673 -3.84582028457138 4.59547362075575e-06 59.6105809243745 21.7772110566717 2.73729178494195 0.00690974693368348 -80.0545969039561 31.4452206893084 -2.54584306133285 0.0118646690817527 CGRRF1 other 0.039208580932288 1 1 2.73729178494195 -2.54584306133285 2.97140783723069e-05 82.1148551615284 49.4627975681769 1.66013366001682 0.098949183848776 -209.178056227601 71.8169750888446 -2.91265478626505 0.00412425938695061 ATP6V1D essential 0.233047516674003 1 1 1.66013366001682 -2.91265478626505 0.0084848133113388 -18.4363461115496 13.9303459005026 -1.32346649847972 0.18766748206281 -63.0592550425006 20.2260153833078 -3.11773000501831 0.00218017090908988 PLEK2 other 1 1 1 -1.32346649847972 -3.11773000501831 3.21790049704423e-05 38.8632308173511 19.5842382463573 1.98441370700644 0.0490099678393548 -76.0883964212827 28.9946505272529 -2.62422188361143 0.00957093594055143 PIGH other 0.251194082411993 1 1 1.98441370700644 -2.62422188361143 2.90562492129588e-06 1.98671335379983 95.024322856479 0.0209074192172933 0.983346055942597 -611.048903172165 133.268907953807 -4.58508224126789 9.21497710910603e-06 PSMA3 essential 0.025316709939251 0.133865972463983 1 0.0209074192172933 -4.58508224126789 1.29982790793341e-09 198.975559351923 75.3518312440629 2.6406200893439 0.0091337423041891 -450.411547693401 111.351740662527 -4.0449439318462 8.27585459171154e-05 VTI1B other 1.45879686107367e-05 1 1 2.6406200893439 -4.0449439318462 5.84102060741814e-07 9.91308518802818 48.1244934566601 0.205988353871313 0.837066877009468 -323.828204144281 67.4932322168283 -4.79793593384227 3.70113194331051e-06 TIMM9 essential 0.00543740608344554 0.053877377698771 1 0.205988353871313 -4.79793593384227 9.85900120062134e-05 83.9844355769049 34.7311249645275 2.41813173810759 0.0167599826322096 -126.007299960285 55.2444593481683 -2.28090384894794 0.023916424329052 GSTZ1 other 0.7235520981136 1 1 2.41813173810759 -2.28090384894794 0.00123947864880374 56.7199731389101 18.0537907221993 3.14172098323739 0.00200792368165382 -6.0458365310821 25.3199275895711 -0.238777797041264 0.811589282538657 KIAA0586 other 1 1 1 3.14172098323739 -0.238777797041264 2.70496854650625e-05 104.29594152467 29.6966286849488 3.51204652323147 0.000582747376080227 -63.3362898802882 47.2364254782676 -1.34083579015579 0.181935471528491 TMED8 other 0.213638415803064 1 1 3.51204652323147 -1.34083579015579 0.0685284915663461 14.7463925714394 12.0619057125136 1.22255909828086 0.223351997806252 -24.1213760236019 19.1860603558616 -1.25723444918865 0.210559836376701 SAMD15 other 1 1 1 1.22255909828086 -1.25723444918865 4.61608787890587e-09 535.73855532892 127.425628667632 4.20432342324403 4.39767933972753e-05 -572.631550759484 203.977082655847 -2.80733278123031 0.00563334961183095 AHSA1 other 5.0218420034617e-05 1 0.418351235588279 4.20432342324403 -2.80733278123031 0.00393497430662749 183.606533718184 58.4639672919598 3.14050760190943 0.00201357337748208 36.6309555047419 82.0736717376735 0.446317981505969 0.655978644597502 DAAM1 other 1 1 1 3.14050760190943 0.446317981505969 0.339037777468095 27.1146461250954 19.7731379244499 1.37128695651122 0.172254840228155 34.1269300454665 31.6519292936045 1.07819430938644 0.282611407713803 ISM2 other 1 1 1 1.37128695651122 1.07819430938644 6.78521313037785e-08 516.779486536686 96.2419059730485 5.3695890715361 2.8141959544188e-07 -39.9670111785954 154.059614340419 -0.259425621372009 0.795648899674497 SPTLC2 other 0.000684748225860727 1 0.00318341846363854 5.3695890715361 -0.259425621372009 0.0415211809222404 62.7198213223675 47.8150728344113 1.31171652795705 0.191542916420221 -127.390466282418 83.850280753025 -1.51926105838139 0.130720918428519 RIN3 other 1 1 1 1.31171652795705 -1.51926105838139 4.38990449466961e-06 780.413124730595 187.102383386998 4.17104854894555 5.01668134455248e-05 -404.426274560445 328.109661798304 -1.23259483534823 0.219581331931402 LGMN other 0.0375512430474038 1 0.474578055194665 4.17104854894555 -1.23259483534823 3.52884368434007e-10 68.8203915530135 14.0265402119958 4.90644096925318 2.31229911263247e-06 -57.8400241970964 22.2975483884254 -2.59400823756576 0.0103898968732683 ALKBH1 other 4.07681403875434e-06 1 0.0246837930273516 4.90644096925318 -2.59400823756576 2.97754687360308e-11 263.810822701275 47.601518748639 5.54206734651336 1.24575253018414e-07 -176.187747470304 75.670632359688 -2.32835040459057 0.0211773192078982 SNW1 essential 3.59896090612405e-07 1 0.0014403390753989 5.54206734651336 -2.32835040459057 0.984839292183969 20.1230864087505 202.889593494163 0.0991824472718923 0.921120747501806 60.8033964028031 355.794697527039 0.170894610924274 0.864528089360944 CHGA other 1 1 1 0.0991824472718923 0.170894610924274 2.73577014091349e-08 783.480952753373 133.099758872767 5.88641902426226 2.3366965701634e-08 73.0104016427283 233.40866149658 0.312800738304213 0.754849826287916 ITPK1 other 0.000283617290508502 1 0.000279912882139874 5.88641902426226 0.312800738304213 0.0227520001041797 3.85242586146823 50.8499554610707 0.0757606536040634 0.939705362502137 -168.524986203559 70.7843464824067 -2.38082280303944 0.0184652251137949 DHRS7 other 1 1 1 0.0757606536040634 -2.38082280303944 9.12061479142553e-09 208.522636954732 53.9321990827163 3.86638484062033 0.000161031499826385 -193.939964668778 75.0749028551606 -2.58328625536738 0.010692596334452 PPM1A other 9.74902515055475e-05 1 1 3.86638484062033 -2.58328625536738 0.0263754008152098 128.328827009579 73.511892200536 1.74568798555077 0.0828090386207924 -97.9867554160667 102.330300998665 -0.957553671393434 0.339750772577758 SIX4 other 1 1 1 1.74568798555077 -0.957553671393434 0.0344277238293114 58.660428323365 22.583755095804 2.59746123151433 0.0103207220944582 53.8408124704771 32.2578715289553 1.66907517199789 0.0971745103319175 GALNT16 other 1 1 1 2.59746123151433 1.66907517199789 0.00528573807673067 14.9422387752671 5.49335552133547 2.72005675169455 0.00726292511682058 -5.89259046732285 9.6133888708278 -0.612956632307276 0.540791911752498 ASB2 other 1 1 1 2.72005675169455 -0.612956632307276 1.17529412131421e-05 35.7877535130325 8.14602639744974 4.39327738051972 2.05309108930612e-05 -2.72603907901077 12.5965766234969 -0.21641110600842 0.828950045346011 CEP128 other 0.0964446355950437 1 0.202332126851118 4.39327738051972 -0.21641110600842 1.78722829116825e-06 24.0000000000005 224.433092168565 0.106936101838203 0.914981616255768 -1463.81824712644 322.892343322568 -4.53345604935602 1.17357971784981e-05 ERH essential 0.0159385019006385 0.170309888654365 1 0.106936101838203 -4.53345604935602 0.000486981890495455 733.232578136443 243.075753546998 3.01647765125481 0.00298972105748111 -248.557773517367 346.170909571515 -0.718020395835767 0.473825552595076 HIF1A other 1 1 1 3.01647765125481 -0.718020395835767 0.0719847439637778 57.9999999999999 164.518121565625 0.352544749770099 0.724921358089376 -418.475574712643 236.692554017184 -1.76801326281798 0.0790782146584355 SUSD6 other 1 1 1 0.352544749770099 -1.76801326281798 0.00928330355654502 346.006085572512 197.033246486456 1.75607970605254 0.0810888905683343 -359.795779808813 284.916209048228 -1.26281260378524 0.208590348065736 SRSF5 other 1 1 1 1.75607970605254 -1.26281260378524 1.3027033819643e-08 557.265506799076 165.280352673183 3.37163793388671 0.000956520979159187 -973.301362604263 285.386638894021 -3.41046576804074 0.000838879503416628 EIF5 essential 0.000138034450352937 1 1 3.37163793388671 -3.41046576804074 3.5153382299936e-09 421.280593871033 67.7015141710521 6.22261701276934 4.3627160207027e-09 61.511084120405 113.181420975078 0.54347333325979 0.587584723310505 DICER1 other 3.85316223389599e-05 1 5.38577292755748e-05 6.22261701276934 0.54347333325979 5.39458241036337e-12 313.345542431672 47.6133530760497 6.58104338779051 7.58603806634292e-10 -114.088953691705 93.7040715264083 -1.21754531935735 0.225334498026576 ZFYVE21 other 6.69090056357369e-08 1 9.60999302244322e-06 6.58104338779051 -1.21754531935735 0.00108892479945683 301.124545373902 127.345608952229 2.36462448804861 0.0192788078357009 -233.362477326049 184.032077542237 -1.26805326790103 0.206668169343277 MTHFD1 other 1 1 1 2.36462448804861 -1.26805326790103 1.28329921541522e-13 446.509909502627 65.7360608492633 6.79246525779055 2.29752247861393e-10 -198.208703005547 114.193179550154 -1.7357315365625 0.0846245875154902 ZC3H14 other 1.66970060917674e-09 1 2.96022074559525e-06 6.79246525779055 -1.7357315365625 6.56216002061114e-09 175.681981019883 38.7913342107439 4.52889761577793 1.27053296178612e-05 -151.514400516136 85.5777376919546 -1.77048850089408 0.0788537764411702 TELO2 essential 7.07466471822087e-05 1 0.127739383977977 4.52889761577793 -1.77048850089408 3.41185686158053e-07 284.389566914232 65.1579307920128 4.36461937107882 2.30800344442527e-05 -80.5061106391568 96.8078292971765 -0.831607435303839 0.406901679975903 PCNX1 other 0.00324092283281535 1 0.226115097450343 4.36461937107882 -0.831607435303839 1.32667240528241e-05 95.7262828196022 41.6874944985441 2.29628294938535 0.0230169814236269 -204.249689047695 68.7946269917266 -2.96897734574908 0.00346963943476083 GSKIP other 0.108256468271045 1 1 2.29628294938535 -2.96897734574908 3.53079950752006e-08 109.249029257721 25.4806213869634 4.28753394976528 3.1857028048192e-05 -93.5136039371501 42.1866613799321 -2.21666282370555 0.0281214546987198 VRK1 essential 0.000363036805363212 1 0.30799374716992 4.28753394976528 -2.21666282370555 1.67772488234851e-09 100.734223904682 20.4005328387437 4.93782317848938 2.02373030145432e-06 -80.2439000715855 35.0695081038017 -2.28813873961599 0.023481066259319 PSMC1 other 1.8721731962127e-05 1 0.0217085549437005 4.93782317848938 -2.28813873961599 0.0159326065903776 148.858900806061 51.059448720786 2.91540360374986 0.00407577103807574 115.936027177025 76.747023097065 1.51062572199571 0.132906764433989 PAPLN other 1 1 1 2.91540360374986 1.51062572199571 1.09256707833826e-06 64.5321821643628 12.6013235594613 5.12106381999144 8.90262089723084e-07 5.69565486602377 22.1195285648224 0.257494405874536 0.797138662937183 RPS6KA5 other 0.00993580501040809 1 0.00975549197918556 5.12106381999144 0.257494405874536 7.52782618843469e-12 397.978881713223 57.1554301184 6.96309835983725 8.88357763775622e-11 -52.2469746702409 100.596096662541 -0.519373776951885 0.604240959142308 PPP4R3A other 9.29234864700378e-08 1 1.15957338905632e-06 6.96309835983725 -0.519373776951885 9.67066321645779e-07 45.9884971849285 11.1981669724939 4.1067879500181 6.6334580340213e-05 -54.8734603724557 26.2088648046572 -2.09369847879504 0.0380037652469003 C14orf93 other 0.00883705204719913 1 0.618503627092146 4.1067879500181 -2.09369847879504 2.34669096715918e-11 593.1493278752 125.857368470326 4.71286929867003 5.70286606921e-06 -988.785738784087 280.044854999129 -3.53081201505081 0.000556810368909311 PSMB5 essential 2.84747481955094e-07 1 0.0591501268698461 4.71286929867003 -3.53081201505081 7.84822768870125e-07 573.492830301867 125.952459270634 4.55324837341686 1.11026668165938e-05 -489.402444612939 301.080923795382 -1.62548473162498 0.106230868948307 ACIN1 essential 0.00721958465083628 1 0.112270166849397 4.55324837341686 -1.62548473162498 3.02943462756715e-11 284.735539028732 48.3885975852901 5.8843519597123 2.45912409966319e-08 -391.953391177217 139.011343748451 -2.81957846466459 0.00544989335693742 CCNB1IP1 other 3.65925408663836e-07 1 0.00029430797224769 5.8843519597123 -2.81957846466459 1.23577227048516e-09 187.286715091972 31.8945147848588 5.87206660315403 2.50851135798382e-08 -56.0191855494803 55.6598537038002 -1.00645585321859 0.315754898136205 TRIP11 other 1.38839014589007e-05 1 0.000300118298869184 5.87206660315403 -1.00645585321859 3.78091558336356e-13 945.488382899627 175.703265397272 5.38116568728443 2.85825242862339e-07 -2365.42537949195 498.041194708584 -4.74945728309887 4.80093794831797e-06 APEX1 other 4.86036698241386e-09 0.0698584480859748 0.00323125437055874 5.38116568728443 -4.74945728309887 0.000239792196320746 282.415781792968 166.869265375904 1.69243737698956 0.0927251923555898 -1214.40501414992 391.685583596691 -3.10045879911771 0.00232492028818172 PABPN1 essential 1 1 1 1.69243737698956 -3.10045879911771 0.000545725411684269 208.321475527283 52.372481741456 3.97768959194432 0.00010948859832719 167.94968862926 123.530992692226 1.35957531765087 0.176074838321184 EFS other 1 1 0.996346244777427 3.97768959194432 1.35957531765087 4.21067943758299e-10 519.935387772994 92.6188054310233 5.6137129533614 9.23390574573311e-08 -192.550613741432 158.603896158826 -1.21403457547229 0.226629869416027 ARHGAP5 other 4.84691310060178e-06 1 0.00107491896786079 5.6137129533614 -1.21403457547229 2.04052846590304e-07 130.341528361767 36.7571203048694 3.54602121386804 0.000527052283947311 -167.398024868868 63.1800016874124 -2.64954131684077 0.00895429013818553 CINP essential 0.00197992477046572 1 1 3.54602121386804 -2.64954131684077 0.974144830342072 -4.16161110415714 19.979914536685 -0.208289734999418 0.835299120359771 1.20448255239843 45.6756373558047 0.0263703501938185 0.978998707445436 DHRS2 other 1 1 1 -0.208289734999418 0.0263703501938185 1.71832994043511e-09 199.86733969138 45.5392457115792 4.38890316623228 2.15444923123432e-05 -201.341228476224 75.0467669924936 -2.68287677864075 0.00812976294118557 SRP54 essential 1.91610971657919e-05 1 0.211739270445709 4.38890316623228 -2.68287677864075 1.09359665206986e-16 637.809135255923 69.5686151441425 9.16805852659875 2.90907935094722e-16 -102.386905520175 232.306054746491 -0.440741441853108 0.660018265616942 CHD8 other 1.50347667726564e-12 1 4.09423827852312e-12 9.16805852659875 -0.440741441853108 2.9450778457322e-06 160.506111025581 34.4531072494156 4.65868317373039 7.17391353906297e-06 -75.0980935070783 78.5651724081775 -0.955870027458397 0.340739859527732 PCK2 other 0.0256369026470988 1 0.0736976137867939 4.65868317373039 -0.955870027458397 9.31048897403116e-09 249.513217152927 90.8476921079534 2.74650033879158 0.00676630233170706 -600.566145206859 149.54924862098 -4.01584194333831 9.35978057455334e-05 KIAA0391 other 9.9473264198549e-05 1 1 2.74650033879158 -4.01584194333831 2.24762045404491e-12 518.68654195686 79.5730501260385 6.51836948734897 1.118601555894e-09 -462.685834231394 181.454472507782 -2.54987285701404 0.0118219424739851 DCAF11 other 2.82368557641662e-08 1 1.40910237995968e-05 6.51836948734897 -2.54987285701404 9.54048159711955e-06 154.784423425237 163.969805025699 0.943981261677892 0.346728148000641 -1007.08160595693 255.997776045817 -3.93394669872715 0.000128424988661456 PSMA6 essential 0.0789474852161643 1 1 0.943981261677892 -3.93394669872715 0.525028918856878 252.216895810521 385.832443500968 0.653695406021209 0.514329314487402 -318.273966824837 598.97302563939 -0.531366110327067 0.59596710848217 NFKBIA other 1 1 1 0.653695406021209 -0.531366110327067 1.05640228922704e-05 34.1126891959273 20.5440863294307 1.66046270683056 0.0989973680296677 -186.295620144441 46.8477247278642 -3.97662044905321 0.000110256473212202 EMC9 other 0.087121496792554 1 1 1.66046270683056 -3.97662044905321 1.12661609520952e-09 48.3172859994341 13.0663007912429 3.6978550219674 0.000303764394733418 -70.6190854931592 20.0343528231835 -3.52489976174522 0.000561056828042676 BRMS1L other 1.2684570615964e-05 1 1 3.6978550219674 -3.52489976174522 0.020170232455848 531.472422905166 289.790108640185 1.83399090258482 0.0686914145941021 -968.975512409636 656.39964100153 -1.47619750512231 0.142044427433969 REC8 other 1 1 1 1.83399090258482 -1.47619750512231 2.20124710854505e-15 459.576627784812 66.9692736723901 6.86249980898755 1.86125173854652e-10 -575.080628215834 151.622884522194 -3.79283529678301 0.000218555848726005 TM9SF1 other 2.97124334711411e-11 1 2.40566787207138e-06 6.86249980898755 -3.79283529678301 0.137513539747477 14.3034790163564 86.3911440852714 0.165566496054715 0.868730332909057 -225.665546028028 130.875708689744 -1.72427372724295 0.0868043411838354 SEC23A other 1 1 1 0.165566496054715 -1.72427372724295 3.02753751357856e-11 192.494749209656 47.1801633167807 4.07999327847158 7.47777925495244e-05 -393.789605009751 97.9185537416782 -4.0216035670688 9.35128792189081e-05 GMPR2 other 3.6572653164029e-07 1 0.69333969251919 4.07999327847158 -4.0216035670688 0.0649645542012347 285.080650804759 152.069329663058 1.87467552751377 0.0628628295902218 -109.285864240728 227.292203198774 -0.480816599525652 0.631376573732655 PNN essential 1 1 1 1.87467552751377 -0.480816599525652 1.98306733270066e-07 155.828912853396 43.3927880241807 3.59112469949062 0.000449971326903247 -230.08172887342 89.9385395413552 -2.55821064080793 0.011547207198557 RABGGTA essential 0.00192635160698543 1 1 3.59112469949062 -2.55821064080793 0.00918185422719769 317.318841182464 103.105024559834 3.07762732744725 0.00249260898218581 208.725502719692 206.442485844727 1.01105885189099 0.313660929108853 NFATC4 other 1 1 1 3.07762732744725 1.01105885189099 0.000223885274925353 1233.44230920554 348.476341751969 3.53952955028281 0.00052940422914231 -1620.15189540362 1563.73645761007 -1.03607733100996 0.301779755701464 PLTP other 1 1 1 3.53952955028281 -1.03607733100996 2.14021869529127e-16 480.497422959268 53.3511902796254 9.00631120769517 7.35824444955004e-16 -56.5721276323682 239.405639067809 -0.236302402285289 0.813509998900893 PCIF1 other 2.93145754694045e-12 1 1.03309752071682e-11 9.00631120769517 -0.236302402285289 0.983622624205836 -13.5961501078864 209.871136606187 -0.0647833252716353 0.948429460032839 -171.265638668041 943.184553589837 -0.181582319193195 0.856146246650245 MMP9 other 1 1 1 -0.0647833252716353 -0.181582319193195 5.20200072948369e-10 592.629314764183 100.158912749113 5.91689045435879 2.16380896357645e-08 -655.06553315106 386.599789723262 -1.69442806376065 0.0922730927172536 PYGB other 5.95837163555062e-06 1 0.000259570523270631 5.91689045435879 -1.69442806376065 1.95560802435927e-06 394.498931989063 74.7873483396738 5.27494209578475 4.59516162336873e-07 228.718130553657 288.668999577716 0.792319684095768 0.429433971456175 ABHD12 other 0.017363843648286 1 0.0051318765009782 5.27494209578475 0.792319684095768 0.00194806939149547 101.59313947715 28.1551345189363 3.60833436646594 0.000420890294219773 132.994852911698 108.59620125041 1.22467315965342 0.222644088754657 GINS1 essential 1 1 1 3.60833436646594 1.22467315965342 8.50061257444839e-08 117.801286617879 20.8563397546788 5.64822437702434 8.04955509589932e-08 -14.2711735299649 80.4442709312117 -0.177404473491571 0.859433258706011 NINL other 0.000851081330953772 1 0.000939463575242409 5.64822437702434 -0.177404473491571 0.728806847112033 18.617446610999 30.6284188334975 0.607848766604877 0.544177359894075 -38.6211092779905 133.136213539252 -0.290087184029791 0.772137259179919 CD40 other 1 1 1 0.607848766604877 -0.290087184029791 0.000816910511348855 340.981999177293 110.463732737852 3.08682307510373 0.00240758519344674 -686.415280405869 506.328645430027 -1.35567143317142 0.177227845057967 ZMYND8 essential 1 1 1 3.08682307510373 -1.35567143317142 0.45123225084474 0.654030444130911 14.8048192170633 0.044176861232936 0.964820286847176 -76.7560998697313 65.2606298440702 -1.17614708980173 0.241339345937263 SGK2 other 1 1 1 0.044176861232936 -1.17614708980173 3.50849169721194e-10 216.726566268047 32.3426397406324 6.70095477691548 3.61835889756057e-10 8.88676306857366 142.568511600657 0.0623332808121473 0.950377732980624 IFT52 other 4.05511470363756e-06 1 4.62751919409021e-06 6.70095477691548 0.0623332808121473 0.00749655162647512 489.750420330946 174.399906706575 2.80820345365748 0.00562311129708625 -354.828000126212 768.766412446324 -0.461555024233042 0.64504754187095 MYBL2 essential 1 1 1 2.80820345365748 -0.461555024233042 0.293119426125392 4.0408605411964 20.3018907357805 0.199038631119942 0.842493377168819 -144.179322746279 99.7260030002115 -1.44575455155836 0.150264966074781 NFATC2 other 1 1 1 0.199038631119942 -1.44575455155836 7.42083903143637e-07 162.843876448725 31.6539303006725 5.144507329798 8.00354640308414e-07 -32.6604628595492 138.809463686671 -0.235289885805426 0.814294317678655 RIMS4 other 0.00683830316746861 1 0.00879269607842824 5.144507329798 -0.235289885805426 0.000453274905876587 206.067039566435 67.6830433328651 3.04458885740403 0.00273837856559393 -425.075168903455 296.805068327238 -1.43216950875918 0.154108862798242 PABPC1L other 1 1 1 3.04458885740403 -1.43216950875918 1.91274114065685e-09 177.846064412179 28.6374745860492 6.21025656008151 4.64643200718233e-09 -51.6383360492155 125.581640285147 -0.411193355429704 0.681498720743383 STK4 other 2.12792451898074e-05 1 5.73044459445796e-05 6.21025656008151 -0.411193355429704 0.285449258366189 19.276360964932 18.1948225604464 1.05944209683236 0.291046648419902 -72.3494805019565 86.029316362394 -0.840986346993484 0.401651096160039 SALL4 other 1 1 1 1.05944209683236 -0.840986346993484 4.51580304775255e-13 821.540950097064 109.680762281428 7.49029212606208 4.99384507183893e-12 -636.825476761448 529.813128748282 -1.20198130662785 0.231215818887064 ADNP other 5.79422689057129e-09 1 6.70124070190066e-08 7.49029212606208 -1.20198130662785 0.0119040039320525 96.1139121623291 32.954145787179 2.91659546519706 0.00406806643399616 14.805553495959 141.281774217753 0.10479450430131 0.916675234554051 PFDN4 other 1 1 1 2.91659546519706 0.10479450430131 0.521019034755816 105.767974198155 137.849637570698 0.767270600504193 0.444095378918551 -347.014733067025 592.31906883351 -0.585857777211904 0.5588287113883 DOK5 other 1 1 1 0.767270600504193 -0.585857777211904 3.6250981284779e-09 188.506947767659 30.7153273856182 6.13722736538122 6.81159807054092e-09 -87.5088050124262 126.557999091142 -0.691452185091882 0.490322479427555 CSTF1 essential 3.96911994087046e-05 1 8.35578735313254e-05 6.13722736538122 -0.691452185091882 0.00383385430857378 460.560580601337 196.413664303424 2.34484999928443 0.0203107967170173 -1353.35107432698 807.91049424708 -1.67512500947053 0.0959390989279123 BMP7 other 1 1 1 2.34484999928443 -1.67512500947053 7.68558902655164e-08 274.983313214258 49.0377974375922 5.60757879805295 9.34157441780349e-08 -109.865688903667 201.343195222955 -0.545663779607791 0.586091746393996 RAE1 essential 0.000772017417717113 1 0.00108698559925561 5.60757879805295 -0.545663779607791 3.88168471594681e-05 308.786668265418 121.841173924537 2.53433759967436 0.012598822283652 -1022.9482742718 418.641473026396 -2.44349482834755 0.0160521792941578 TPD52L2 other 0.299277891599499 1 1 2.53433759967436 -2.44349482834755 8.44471524056591e-05 284.774253352766 84.0433574621427 3.38842071464175 0.00096092071536191 -339.57998671807 288.769664906763 -1.17595449933327 0.242020848609755 DNAJC5 other 0.625163984982612 1 1 3.38842071464175 -1.17595449933327 2.26263570601614e-11 511.022485444298 70.8895953942504 7.20870929791969 2.74689525979186e-11 -84.7979306775017 287.655645506131 -0.294789732105899 0.76857041831752 NELFCD essential 2.74729227424479e-07 1 3.63112084391886e-07 7.20870929791969 -0.294789732105899 0.238786921419226 168.541938539461 133.116325305802 1.2661252340934 0.207471034433546 793.699805464985 541.079677556041 1.46688156733216 0.144544389441351 CTSZ other 1 1 1 1.2661252340934 1.46688156733216 1.98077513113608e-08 730.989374458117 133.80919727166 5.46292324715211 2.71082146322911e-07 -298.161762806912 459.763129703448 -0.648511686874999 0.51793579733488 PRPF6 essential 0.000207446579483882 1 0.00307000530710697 5.46292324715211 -0.648511686874999 0.000548169910140001 3.82659767262536 1.1011904426196 3.47496447891642 0.000671740167021565 -3.50987744685514 4.47602326950981 -0.784150848983303 0.434213342135411 TUBB1 other 1 1 1 3.47496447891642 -0.784150848983303 0.00298739318127021 326.735444123047 94.6505560526785 3.45201822101499 0.00072681522153835 247.508315686881 384.727359561894 0.643334323737021 0.521009515753915 PRELID3B other 1 1 1 3.45201822101499 0.643334323737021 7.14508670329102e-13 170.460959166773 21.9583620662264 7.76291777376943 2.0935835406051e-12 -31.6781139017488 81.0720840613715 -0.390740095909815 0.696624072103627 MTG2 essential 9.10927103802572e-09 1 2.82822200500343e-08 7.76291777376943 -0.390740095909815 0.0165292322247516 477.673658641966 171.84124707003 2.77973808259958 0.00621717303281715 40.9106217957834 637.128358383156 0.0642109572702155 0.948897234461191 PSMA7 essential 1 1 1 2.77973808259958 0.0642109572702155 0.0120834767099106 -44.6306113836578 15.34091879002 -2.90925282863058 0.00433081786518037 -110.257160943187 53.6070496327502 -2.05676607271868 0.0419132970759377 SLCO4A1 other 1 1 1 -2.90925282863058 -2.05676607271868 0.731749627309122 -0.629142717378009 1.42119116671055 -0.442686903855591 0.658802644546345 -3.90124740124739 4.97296044075654 -0.784491943526077 0.434323571324646 NTSR1 other 1 1 1 -0.442686903855591 -0.784491943526077 7.63642521170731e-05 69.8785618197382 22.6881777700689 3.07995479090104 0.00257605980668606 -127.73566973567 79.3893271828811 -1.60897785972437 0.110293408517795 MRGBP essential 0.56876094976796 1 1 3.07995479090104 -1.60897785972437 0.00174617192912931 37.1338408993881 19.8795412165921 1.86794254931773 0.0642719837938015 -138.037996299986 69.2705086095553 -1.99273831058524 0.0486178765810216 TCFL5 other 1 1 1 1.86794254931773 -1.99273831058524 4.54111115656286e-08 409.641810160808 81.3851513872559 5.03337283494879 1.76357491642756e-06 -312.160274654902 283.587572189822 -1.10075442391373 0.273263058201416 DIDO1 essential 0.000463374982415675 1 0.0189743025258442 5.03337283494879 -1.10075442391373 2.21809641559376e-08 400.238437455529 85.3079960057785 4.6916872531904 7.40997683303005e-06 -544.924149708267 297.256773051184 -1.83317656353094 0.0693185141340154 GID8 other 0.000231436180003053 1 0.0760337722837214 4.6916872531904 -1.83317656353094 0.345306435923242 12.3065319481998 29.4723843466573 0.417561463757021 0.677033044459624 -110.140849580191 102.696889801727 -1.07248476358764 0.285709503571414 SLC17A9 other 1 1 1 0.417561463757021 -1.07248476358764 0.13067942903166 26.9681056402071 20.6443641984693 1.30631805275973 0.194028680531596 -57.8066201443921 70.8493183339409 -0.815909334115632 0.416224248851572 NKAIN4 other 1 1 1 1.30631805275973 -0.815909334115632 2.21435670507839e-07 294.876969618232 63.2718525795161 4.66047630338703 8.4865710912875e-06 -260.028999090589 217.142440517335 -1.19750426711184 0.233551361964225 ARFGAP1 other 0.00213951144844674 1 0.0867327565529583 4.66047630338703 -1.19750426711184 0.164671031951196 17.8335313004584 9.80859877635086 1.81815279705967 0.0716212207029386 9.19771347970528 33.6620944309398 0.273236518261662 0.785157279095434 CHRNA4 other 1 1 1 1.81815279705967 0.273236518261662 0.713268757166752 -6.49843172918056 64.5634771695217 -0.100651823818564 0.920000614167376 -172.043113527959 221.575162245429 -0.77645486878802 0.43906080860429 EEF1A2 other 1 1 1 -0.100651823818564 -0.77645486878802 0.0481607101687856 -57.8570832018706 25.2894443331418 -2.28779574749489 0.0239613652477463 -165.875689018392 86.7907519370392 -1.91121387148165 0.0584446969281091 PTK6 other 1 1 1 -2.28779574749489 -1.91121387148165 1.59812918141669e-06 139.045164343646 33.1506269971107 4.19434493217172 5.37776158655593e-05 -146.596648169113 113.769516101745 -1.28854066706244 0.200121879618553 GMEB2 other 0.0143160412071307 1 0.506907807148762 4.19434493217172 -1.28854066706244 2.63568793118877e-07 309.398243488794 64.8807369127981 4.76872270893957 4.39648531196363e-06 -321.558449424592 243.620356186985 -1.31991617801341 0.188900926444541 C20orf27 other 0.00252815186359627 1 0.0460399941868831 4.76872270893957 -1.31991617801341 0.549312006251557 17.020391681809 16.3958968543371 1.03808848232091 0.300921891053899 3.15556228548352 61.5648715122835 0.0512558900549954 0.959190729618264 SPEF1 other 1 1 1 1.03808848232091 0.0512558900549954 0.0149994821534553 254.817174710697 103.163642755463 2.47002885808047 0.0146232164493887 -203.015321962824 382.522348270113 -0.530728002902114 0.596386977603076 CDC25B other 1 1 1 2.47002885808047 -0.530728002902114 0.974179022224134 3.01487278436254 19.1115262742537 0.157751544335004 0.874861952808612 -6.30867798803952 60.2611069161508 -0.104689049220712 0.916760567478769 ISM1 other 1 1 1 0.157751544335004 -0.104689049220712 0.000981285470709018 197.384208847499 60.4633573413688 3.26452611179183 0.00135112444039386 -118.408763689355 221.443428860926 -0.53471337712947 0.593619247274253 RNF24 other 1 1 1 3.26452611179183 -0.53471337712947 0.0049480605812762 89.1308717358624 35.8550468299654 2.48586683371369 0.0143483058294269 -108.68656854921 123.050804680288 -0.88326580904205 0.378919538848157 ARFRP1 other 1 1 1 2.48586683371369 -0.88326580904205 0.000198055845804644 46.894280245594 12.8783349156296 3.64133100690536 0.000372085309757238 -35.4031718412092 40.0019705634888 -0.885035695554532 0.377544522931709 NDUFAF5 other 1 1 1 3.64133100690536 -0.885035695554532 0.321035295710007 71.8189087995562 47.4927847982302 1.51220673002591 0.13258526572766 104.313989769033 171.252525944291 0.609123802372213 0.5433638330197 TRIB3 other 1 1 1 1.51220673002591 0.609123802372213 0.257828590198309 36.3820129239663 25.1238013997185 1.44810939814124 0.149619328782928 -20.6215755499167 86.6888526961585 -0.237880360721749 0.812290090555387 RASSF2 other 1 1 1 1.44810939814124 -0.237880360721749 5.54743845807678e-15 687.905479114344 89.1436882755564 7.71681643896005 1.54823244056694e-12 -510.203752638635 321.44002197463 -1.58724401990895 0.114563136788435 CSNK2A1 other 7.43578650920612e-11 1 2.09630672452763e-08 7.71681643896005 -1.58724401990895 0.000199229494670194 62.4537897012699 16.3760549134141 3.81372620154762 0.000199005948250068 -20.0052757392125 59.0955259784592 -0.338524370635175 0.735438316614398 SLC52A3 other 1 1 1 3.81372620154762 -0.338524370635175 0.158921182214911 34.3556358445962 22.9970754060825 1.49391325800973 0.137257755433158 -50.7460413042509 82.8361945725512 -0.612607104492294 0.541045609144271 RSPO4 other 1 1 1 1.49391325800973 -0.612607104492294 1.58571330545712e-10 203.97945575131 30.9932214083581 6.58142156517819 6.90381226372525e-10 -52.4907592856886 106.832161765845 -0.491338548411463 0.623886537874943 CDS2 other 1.86131027794557e-06 1 8.7567954753091e-06 6.58142156517819 -0.491338548411463 0.346645964641058 9.20043629605126 11.7844169495858 0.780729019977065 0.43616033259881 -35.4723534785553 41.339357435247 -0.858077040363252 0.392183430749792 SNPH other 1 1 1 0.780729019977065 -0.858077040363252 0.278957156749445 -7.65148695903244 8.40730914184847 -0.910099394459777 0.364201614245503 -45.9553110262744 29.3636984747729 -1.56503824154698 0.119639919552875 SIRPB1 other 1 1 1 -0.910099394459777 -1.56503824154698 6.90098866667927e-13 368.999096101655 56.0961269519046 6.57797812704655 7.02971283707177e-10 -342.67690176351 177.763809720377 -1.92770903314089 0.0557317264250344 SEC23B other 8.80152094548274e-09 1 8.91086399227218e-06 6.57797812704655 -1.92770903314089 0.131601384321488 -16.3689296081278 18.0180098308009 -0.908476006054002 0.365064940256361 -128.410693033382 63.5936224464247 -2.01923853514656 0.0452200892717016 FERMT1 other 1 1 1 -0.908476006054002 -2.01923853514656 0.144219487980175 -33.0820904875297 19.7389712108372 -1.67597845572452 0.0957847279588476 -111.740036345407 69.7549529345568 -1.6018939393485 0.11124168414265 PDYN other 1 1 1 -1.67597845572452 -1.6018939393485 6.80526034901324e-06 107.134154208305 21.1905736543801 5.05574582149927 1.21774703852845e-06 97.4212152420188 69.5915511891583 1.39990003926218 0.163580981984394 PLCB4 other 0.057075718547174 1 0.0132369103088043 5.05574582149927 1.39990003926218 4.80700374626105e-19 227.195848190398 23.4197674635423 9.70102920723165 1.22140077894825e-17 -7.78591825405954 77.3946622488642 -0.100600196807162 0.9199995456051 CRNKL1 essential 6.75384026349677e-15 1 1.73231272478231e-13 9.70102920723165 -0.100600196807162 0.159488753553361 6.28129372545733 3.51211967667446 1.78846232580688 0.0756932844073432 -0.627983003088584 11.2980357594603 -0.0555833789570679 0.955746700058004 PAK5 other 1 1 1 1.78846232580688 -0.0555833789570679 6.0690464574872e-06 39.7950792233877 8.25710586687171 4.81949485267584 3.53145823267761e-06 -1.746987279625 40.7194627284914 -0.0429030041794396 0.96583668148201 MROH8 other 0.0511681306830746 1 0.0372251012306547 4.81949485267584 -0.0429030041794396 4.81082507794741e-08 229.284415308341 40.5828182270772 5.64979036264565 7.91412264666613e-08 -96.7638398398124 200.969948886766 -0.481484124247515 0.630878840812844 MANBAL other 0.000489741992935046 1 0.000924369525130604 5.64979036264565 -0.481484124247515 5.20222794484174e-13 525.066546039405 74.3634748061909 7.0608124137267 5.74998912828613e-11 -413.365601125855 276.864455909802 -1.49302516918431 0.13753100020925 IDH3B other 6.66249332895882e-09 1 7.54168574066009e-07 7.0608124137267 -1.49302516918431 0.0453634416558439 250.892911077552 115.2895815726 2.17619760307275 0.0310949581938888 -157.708048325486 375.756108469009 -0.419708541713548 0.67529493227637 JAG1 other 1 1 1 2.17619760307275 -0.419708541713548 2.32111415746741e-14 251.419017320609 31.2791712046129 8.03790534205493 2.51688297726356e-13 -71.5930422999882 142.906870551015 -0.500976909115302 0.61712172888022 TTI1 essential 3.07594048147581e-10 1 3.44510941927837e-09 8.03790534205493 -0.500976909115302 9.97634780647615e-08 171.917992223401 35.8097243556642 4.80087449196486 3.78669025613365e-06 -264.158566042182 163.605858016077 -1.614603347615 0.108498204236838 RPRD1B essential 0.000992846133700507 1 0.0398477798614576 4.80087449196486 -1.614603347615 0.0471399019842522 1886.76978638606 822.996255911338 2.29256181037757 0.0232542953298741 -466.423084305243 3100.50180820762 -0.150434708043237 0.880622424530833 CST3 other 1 1 1 2.29256181037757 -0.150434708043237 0.390874069874616 6.74775530754384 6.91135335917389 0.976329085907192 0.330462949137455 -16.0849326891955 26.6969024773334 -0.602501833418773 0.54774387480161 CST4 other 1 1 1 0.976329085907192 -0.602501833418773 6.15535621101136e-08 31.0535045355525 6.42542089058615 4.83291368212919 3.27772821326332e-06 -50.8079161816065 29.5570836488592 -1.71897595802107 0.0876680520201934 ACTR5 other 0.000622614280743799 1 0.0346291985731269 4.83291368212919 -1.71897595802107 0.368174807992903 2518.50513706373 2432.85315803881 1.03520639079342 0.302174600539064 -5987.54258879071 10684.2699803605 -0.560407271605533 0.576005602792792 WFDC2 other 1 1 1 1.03520639079342 -0.560407271605533 0.0635745224019764 83.5805921052631 50.8056295185174 1.64510494008937 0.102028287062999 -231.392675129725 233.340564688841 -0.991652160601767 0.322953639106337 PPP1R16B other 1 1 1 1.64510494008937 -0.991652160601767 0.0333421996634236 78.330592105263 45.3905503911815 1.72570262819464 0.0864465706049274 -256.963097664937 208.470139238315 -1.23261345055843 0.219635696637955 FAM83D other 1 1 1 1.72570262819464 -1.23261345055843 7.75845935894268e-16 99.8956476624201 12.1174112143568 8.24397603541451 7.48917185103298e-14 -66.3416181472301 55.8577343804535 -1.18768902611355 0.23682081705829 DHX35 other 1.05484013444185e-11 1 1.0309593970132e-09 8.24397603541451 -1.18768902611355 4.59904245051936e-08 153.24889599288 27.7547478879571 5.52153803059314 1.37379176446228e-07 -93.5563469340955 120.820066790105 -0.774344439791002 0.439899130355466 DNTTIP1 other 0.000469010349103964 1 0.00158466880030723 5.52153803059314 -0.774344439791002 0.00307334257994262 211.354970004028 61.0087065791942 3.46434110563666 0.000693152659941366 227.7221079855 235.491083072162 0.96700947235322 0.335095837239028 SYNDIG1 other 1 1 1 3.46434110563666 0.96700947235322 6.87786889076787e-09 151.39926715005 25.5495455823791 5.92571271617707 1.92316311717443e-08 -80.1941955173688 114.822538888509 -0.698418588315979 0.485955283367579 ACOT8 other 7.40815258224608e-05 1 0.000231298828102569 5.92571271617707 -0.698418588315979 3.27553265421056e-07 482.794849822187 86.3137885662167 5.59348463139009 1.03553914355594e-07 185.280086060732 332.922131038869 0.556526793465406 0.578685665729383 APMAP other 0.00311535910741966 1 0.00120226094566845 5.59348463139009 0.556526793465406 5.50232459726926e-05 51.1283613780576 14.5073204993033 3.52431459555285 0.000562202277338324 -2.58793279084883 32.6276210075519 -0.0793172383070722 0.936885313402051 CELF4 other 0.416801088243147 1 1 3.52431459555285 -0.0793172383070722 8.60043210678574e-10 319.778536458951 63.0220370935011 5.07407489834895 1.15845495472485e-06 0.0694136934435242 116.009676733049 0.000598343995072519 0.999523401817454 ZNF516 other 9.74514962019892e-06 1 0.0126144160019989 5.07407489834895 0.000598343995072519 6.96041175847837e-08 226.583072420098 39.3075187593207 5.76436975855592 4.33898615381156e-08 223.141285497932 74.2141201130198 3.00672277941331 0.00308477353860996 CDH20 other 0.000701957525842544 1 0.000513562401165136 5.76436975855592 3.00672277941331 5.3879837365735e-05 77.6985761966075 35.5358135534543 2.18648648861607 0.0308416081121903 -88.2090203382627 65.1429004899132 -1.35408493749708 0.178411076961523 ADNP2 other 0.4086785664191 1 1 2.18648648861607 -1.35408493749708 4.28452592620984e-07 48.6446429241098 19.5024185299992 2.49428771356142 0.014067745254901 -69.4383289373351 35.7510911548804 -1.94227159771195 0.0545928474737459 RBFA other 0.00403816568545277 1 1 2.49428771356142 -1.94227159771195 4.2234628965015e-22 516.551519393113 54.7430060505088 9.43593632612201 1.15921761322952e-16 -205.352212662583 145.15841528759 -1.41467659491691 0.159383612537705 USP14 other 6.02519216814904e-18 1 1.63554013050553e-12 9.43593632612201 -1.41467659491691 8.4246479120798e-16 436.236952622365 84.613411324907 5.15564785524672 7.86318130207219e-07 -956.254284681123 228.148423628797 -4.19136923881171 4.71859974841611e-05 VAPA other 1.14482540477252e-11 0.679242433784499 0.00864320888723775 5.15564785524672 -4.19136923881171 8.51827286405625e-20 72.0858706874722 9.11138594028793 7.91162520827146 5.78844922216425e-13 -61.3183176514131 24.2077956760102 -2.53299881046911 0.0123653790880703 METTL4 other 1.20209866657562e-15 1 7.89081397965431e-09 7.91162520827146 -2.53299881046911 1.8217689557558e-12 470.760960273815 66.4094899010225 7.08876037107712 5.04328774385061e-11 38.1896031227169 177.077217816861 0.215666383251028 0.82954275149554 LPIN2 other 2.29470017667001e-08 1 6.62587143787093e-07 7.08876037107712 0.215666383251028 8.85718446585747e-24 451.26168574723 40.8673327930877 11.0421124870561 4.70100461679163e-21 56.1241353704998 108.431373880407 0.517600518761305 0.605509809836233 SMCHD1 other 1.27127168638452e-19 1 6.74829212740438e-17 11.0421124870561 0.517600518761305 0.00658540134685059 9.88988317855714 6.24775828780008 1.58294907116829 0.115553364829645 -26.6598311667979 16.4238549624378 -1.62323834615992 0.106652289518269 MYOM1 other 1 1 1 1.58294907116829 -1.62323834615992 8.37420431388848e-05 248.275764210045 261.203231002168 0.95050801346322 0.343393419203331 -2260.00032802447 686.640517139836 -3.29138795572155 0.00124476477377098 MYL12A other 0.620444797615998 1 1 0.95050801346322 -3.29138795572155 1.43827147164805e-23 71.7235722215369 7.30069734383407 9.82420840690133 9.45803574244699e-18 -24.8494070380094 19.5366957374189 -1.27193499719684 0.205446498367076 CEP76 other 2.06305659893196e-19 1 1.34190611113838e-13 9.82420840690133 -1.27193499719684 0.651282849117702 10.5151927726454 19.1801503507905 0.548233073272651 0.584357856971734 -6.31911300647147 38.7590828856775 -0.163035668958167 0.870712755965442 ST8SIA5 other 1 1 1 0.548233073272651 -0.163035668958167 1.06612181410553e-14 172.104148074109 24.5047150388409 7.02330746557619 8.0978884099294e-11 -68.695367626935 65.6509427458857 -1.04637290423739 0.297154353941815 CEP192 essential 1.42114037820267e-10 1 1.05807009964138e-06 7.02330746557619 -1.04637290423739 1.85692730699741e-27 484.546075644951 43.0380565986937 11.2585491525112 2.23916597937093e-21 -129.461175484624 115.361854523115 -1.12221822386432 0.26367704551563 RNMT essential 2.68567396411036e-23 1 3.21566626297459e-17 11.2585491525112 -1.12221822386432 0.0370500794801436 53.4241824701823 31.6531764970714 1.68779845760899 0.0935561751812224 -16.3969243567116 63.1836337170661 -0.259512208970703 0.795600698838983 SMAD7 other 1 1 1 1.68779845760899 -0.259512208970703 0.0293644526909427 32.4296401482353 30.449381495818 1.06503444586187 0.288583181533112 -64.1092240155162 61.3608868983453 -1.04478972283637 0.297812216474684 LIPG other 1 1 1 1.06503444586187 -1.04478972283637 0.000458734844085253 333.981317864051 92.4076317657307 3.61421791125165 0.000408997727022223 89.6245723635307 252.169718388603 0.355413698901848 0.722772412423365 LAMA1 other 1 1 1 3.61421791125165 0.355413698901848 0.000134339783906548 55.0230392112277 14.512448687548 3.79143729606698 0.000216527810041104 13.65756573861 38.6824739801847 0.353068569130459 0.72453270999361 RNF125 other 0.967918143046677 1 1 3.79143729606698 0.353068569130459 4.02361384869453e-14 223.808203561903 29.5991318381249 7.56130972982217 3.69260967710957e-12 9.37606469930285 79.2406146119914 0.118323977485707 0.90596926325658 ANKRD12 other 5.304330136734e-10 1 4.96434444990611e-08 7.56130972982217 0.118323977485707 4.05133290097526e-15 91.4537883838177 19.5976755504962 4.66656303948771 6.67082817573881e-06 -74.8929523769842 36.4227995401325 -2.05621076146174 0.041472470673084 POLI other 5.44296575246026e-11 1 0.0687695676636914 4.66656303948771 -2.05621076146174 1.43994940838906e-09 220.911393703043 36.9794881765206 5.97388997512698 2.05376075919824e-08 15.7407323012019 103.143615217929 0.152609856343932 0.878940756848338 MIB1 other 1.61159137786904e-05 1 0.000246636129572116 5.97388997512698 0.152609856343932 1.03749716406838e-16 413.40873893564 47.6418393659071 8.67743026797322 1.05183981539009e-14 -28.8755294969621 145.670928322983 -0.198224380316565 0.843163353200953 RIOK3 other 1.42686984974324e-12 1 1.46289881524454e-10 8.67743026797322 -0.198224380316565 6.79067035386864e-07 68.6786252463198 33.9196936122776 2.02474191044759 0.0446446116405235 -219.833796993934 69.1818684940629 -3.17762156153385 0.00179897461523899 EEA1 other 0.00628476541250543 1 1 2.02474191044759 -3.17762156153385 0.598262796726367 -3.40319337868169 9.01606821276739 -0.377458699110387 0.706355828911848 -15.0817891409486 15.2035366394275 -0.991992159366187 0.322767591147784 RUBCNL other 1 1 1 -0.377458699110387 -0.991992159366187 0.97091018622362 -0.930774939043796 4.81687396691786 -0.193232155426181 0.84703013195964 0.521043146400912 9.50973140037925 0.054790521883734 0.956375910082083 NALCN other 1 1 1 -0.193232155426181 0.054790521883734 0.674331048469357 -11.5263597493005 15.8938982382218 -0.725206590387111 0.469418734500021 -24.0625977789128 31.3785878950791 -0.766847694337655 0.444338500415321 FGF14 other 1 1 1 -0.725206590387111 -0.766847694337655 1.64749414352204e-05 200.912725369774 60.5176068437019 3.31990532753004 0.00114266654360179 -192.092813839136 110.292048774778 -1.74167418207453 0.0837158135073992 NDFIP2 other 0.132952777382228 1 1 3.31990532753004 -1.74167418207453 0.12976158173907 -47.58815561706 26.1432085749661 -1.82028749380934 0.0706694803530186 4.10143340081439 52.4131959284066 0.0782519235502584 0.937729905486341 TNFSF13B other 1 1 1 -1.82028749380934 0.0782519235502584 8.62543965034103e-15 512.042665575762 70.1546044568233 7.29877489211559 1.60980559217533e-11 -38.0702790829188 118.956505853656 -0.320035283566199 0.7493899172704 FNDC3A other 1.15235873728556e-10 1 2.13766084584962e-07 7.29877489211559 -0.320035283566199 4.7218729017318e-07 19.3571761778884 5.78677447370241 3.34507181260574 0.00104249070415407 -18.9757729868499 9.82585659737152 -1.93120801212649 0.055368606345895 CDADC1 other 0.00443194990556547 1 1 3.34507181260574 -1.93120801212649 1.85102706077752e-06 59.3002643445811 19.644292047442 3.01870203320985 0.00299033142387102 -66.7672761531918 33.3557143953381 -2.00167429669932 0.047147405679929 CAB39L other 0.0164870980303454 1 1 3.01870203320985 -2.00167429669932 0.000148916251138642 660.358537775086 168.611365357037 3.91645329706434 0.00013790282138408 49.893458009049 316.220859039781 0.157780413855534 0.874849342784327 KLF5 other 1 1 1 3.91645329706434 0.157780413855534 1.67458257733633e-11 1457.41491325212 222.908071984152 6.53818814311822 8.7867351470265e-10 -334.387667887667 428.154656944379 -0.780997386024245 0.436010773856455 STK24 other 2.04299074435032e-07 1 1.11152199609885e-05 6.53818814311822 -0.780997386024245 0.0121211585983792 63.1656022837636 49.9347597152359 1.26496257604882 0.207846407838634 -339.95403043056 181.809232070892 -1.86983920760418 0.0634551417033935 ACP5 other 1 1 1 1.26496257604882 -1.86983920760418 0.000457159949113936 123.005501048946 46.3905559096958 2.65152030702949 0.00886825809074798 -136.452990677792 86.6458702576637 -1.57483548000631 0.117387283311751 DNAJC3 other 1 1 1 2.65152030702949 -1.57483548000631 2.84264798656627e-10 114.982284256353 17.2091049511057 6.68147963435863 4.27372949285197e-10 20.0878570752559 32.142272184593 0.624966927038992 0.532936037550443 UGGT2 other 3.29804019401419e-06 1 5.45456095172697e-06 6.68147963435863 0.624966927038992 4.23776143318553e-09 278.158152579432 44.0667043001289 6.31220684635175 2.86736587629854e-09 45.5132937385101 80.8638665300597 0.562838455437835 0.574374120827972 ARHGEF7 other 4.61788863374227e-05 1 3.56270210130093e-05 6.31220684635175 0.562838455437835 0.000359894224523408 57.5648866616865 27.8816400241552 2.06461623533678 0.0406928817241453 -78.5437839783192 45.3450288649006 -1.73213659676632 0.0853186718026787 FGF9 other 1 1 1 2.06461623533678 -1.73213659676632 0.0551836277137419 16.7749467025163 6.93300777404762 2.41957707956279 0.0167191331081357 13.7980650499978 11.3300558674587 1.21782850953344 0.225176252368908 SGCG other 1 1 1 2.41957707956279 1.21782850953344 7.31133866637196e-09 559.246072303166 147.400195032131 3.79406602671904 0.000211587718062175 -562.492003712442 245.864092737646 -2.28781680744517 0.0234915480511432 PARP4 other 7.85530226315004e-05 1 1 3.79406602671904 -2.28781680744517 5.21402769356971e-15 335.183353879488 53.1183019774874 6.31012930386113 2.97654631079194e-09 -190.883888079495 91.0558716666703 -2.09633804592269 0.0377309917533125 SUPT20H other 6.99096833153827e-11 1 3.6953822448482e-05 6.31012930386113 -2.09633804592269 2.18329738508981e-18 95.5481294007113 15.4654203836054 6.17817860948675 5.47003362140925e-09 -89.478480718682 26.5411486607024 -3.37131153826686 0.000944547741466471 MRPS31 essential 3.05508803095617e-14 1 6.73087637114408e-05 6.17817860948675 -3.37131153826686 2.80512185360979e-08 33.5905292993697 7.36822609211634 4.5588353125198 1.03770220139579e-05 -12.1014050607523 12.6450609958095 -0.957006460052873 0.340054281401214 SLC25A15 other 0.000290554521596902 1 0.10521262619952 4.5588353125198 -0.957006460052873 1.77777930951211e-08 215.7058000311 47.2065221950873 4.56940672603813 1.02360264438319e-05 -88.6861525515198 80.1559693845807 -1.10641981168005 0.270340019801478 KPNA3 other 0.000186842421154457 1 0.103854724299119 4.56940672603813 -1.10641981168005 0.812260985803257 -12.5944852637659 31.4129062465673 -0.400933462345343 0.689021254124487 11.0633479182151 51.4398897725151 0.215073320863265 0.829992878604938 FLT1 other 1 1 1 -0.400933462345343 0.215073320863265 0.146298924650966 -44.2284724073577 106.547926135475 -0.415104019491861 0.678639774398046 -336.379056251666 184.415369800189 -1.82402939958923 0.0700736109342553 RGCC other 1 1 1 -0.415104019491861 -1.82402939958923 0.119063777306917 23.6455935237028 20.9411266496599 1.12914619730294 0.260603429646195 -29.2938389792941 35.9859650881462 -0.81403510806338 0.416889961423019 DGKH other 1 1 1 1.12914619730294 -0.81403510806338 0.0005720061872953 44.1703962657485 13.1722313142655 3.35329643185904 0.00100232126282879 -0.676923894911113 21.7983909018759 -0.0310538469540364 0.975266291068238 KATNAL1 other 1 1 1 3.35329643185904 -0.0310538469540364 1.90796952177851e-14 346.226342710997 50.7891369871206 6.81693691308036 2.23922631724973e-10 -91.4971760443309 85.5432247002016 -1.0696016705589 0.286551806144391 INTS6 other 2.53244794625662e-10 1 2.88569095503973e-06 6.81693691308036 -1.0696016705589 7.1466868666083e-08 53.3209718670076 12.4639678371412 4.2780094239426 3.38097593502971e-05 -27.0378836317136 20.9928355667676 -1.28795767230776 0.199784472142148 DHRS12 other 0.00071995723494212 1 0.325486553265311 4.2780094239426 -1.28795767230776 0.747193438599066 -14.6206431602204 19.2714065758187 -0.75867026637101 0.449194550073215 -10.3931363016395 32.1117030264652 -0.32365571807493 0.746632187175102 MEDAG other 1 1 1 -0.75867026637101 -0.32365571807493 7.06308493712891e-07 1574.98943779109 508.829277348473 3.09531999809133 0.00234109802239109 -1843.77972388556 875.591974096699 -2.10575219786327 0.0368695758954916 TSC22D1 other 0.00652275893943855 1 1 3.09531999809133 -2.10575219786327 4.601217084902e-06 175.574236639491 70.8497027007134 2.47812241896285 0.0143468629650702 -380.643979722316 130.197190858136 -2.92359594867964 0.00401215479055349 CLN5 other 0.0392483817342141 1 1 2.47812241896285 -2.92359594867964 0.0921438085067149 203.734778883229 98.8078528281705 2.06192901729713 0.0409997889549566 74.4670585995142 172.778765264065 0.43099658968915 0.667110887434019 OLFM4 other 1 1 1 2.06192901729713 0.43099658968915 0.0016989323241762 4870.19437401907 2434.44116334207 2.00053895216474 0.0475093296650277 -7332.73797235301 5207.00426088597 -1.40824504935307 0.161427350012847 MSLN other 1 1 1 2.00053895216474 -1.40824504935307 1.62968006685856e-25 1014.64837713347 80.6603062893702 12.5792775134452 1.87111137943576e-25 21.5546168678139 254.530058142079 0.0846839741645841 0.932621916999089 MGRN1 other 2.34950975238998e-21 1 2.70394305442262e-21 12.5792775134452 0.0846839741645841 7.60242285234921e-05 278.812294769466 65.9997010934548 4.22444784067539 4.09882357373387e-05 71.7168587276014 135.789990424217 0.528145399403545 0.59816360973613 ZNF629 other 0.566456526728539 1 0.390822827755525 4.22444784067539 0.528145399403545 2.82075343469197e-07 56.0864986434389 36.4541773431674 1.53854791771762 0.126255304777587 -172.506199723927 58.4772928714121 -2.94996897519277 0.00374742505876098 TRADD other 0.00269748650959593 1 1 1.53854791771762 -2.94996897519277 0.00176544638677707 53.7485720405547 45.5651459190102 1.179598374075 0.240234549653606 -120.828656766147 73.0924842316871 -1.65309276372584 0.100635682801377 HSF4 other 1 1 1 1.179598374075 -1.65309276372584 0.00838447209409099 -289.253754951737 108.08107298033 -2.67626650046654 0.00824541245770439 -616.411772582715 231.050366280006 -2.66786754120829 0.00844490366857696 CORO1A other 1 1 1 -2.67626650046654 -2.66786754120829 0.000448290821298596 9.20913909501814 143.21367552458 0.0643034896024129 0.94881143071055 -1093.35381353568 306.155104439813 -3.57124149713669 0.0004735690327896 MAPK3 other 1 1 1 0.0643034896024129 -3.57124149713669 0.00662497095741808 -39.4465826033587 19.0069313015938 -2.07537881720291 0.0396035894168725 -127.182302069966 40.6320766253995 -3.13009603822373 0.00208873911632497 GDPD3 other 1 1 1 -2.07537881720291 -3.13009603822373 3.26445130832541e-08 104.407685659199 78.7411126090464 1.32596152377968 0.187043000805817 -429.579194645746 124.075979584214 -3.46222690391235 0.000713620521567084 ELMO3 other 0.000336630218914516 1 1 1.32596152377968 -3.46222690391235 0.000508079050458805 216.925874582076 95.1269259976811 2.2803835224042 0.0240530744879962 -119.803040382494 141.017566322491 -0.849561111475416 0.396979365070637 PHKB other 1 1 1 2.2803835224042 -0.849561111475416 8.2900274576811e-08 314.320232670982 63.5618714180697 4.94510664425819 1.93811762741755e-06 -167.447447838385 173.597320898564 -0.964573917222071 0.33624165311483 LYRM1 other 0.00083057785098507 1 0.0208095689655822 4.94510664425819 -0.964573917222071 3.36830307224226e-07 388.03801572751 236.389482553457 1.64151979832588 0.102871819891755 -1045.4201528306 377.084779669415 -2.77237430199942 0.00630110060609855 NUTF2 essential 0.00320123523985905 1 1 1.64151979832588 -2.77237430199942 4.17742789260555e-06 385.913102168227 132.310415065159 2.91672505129831 0.00408487003311817 -216.125175764222 211.67799970296 -1.0210091557342 0.308904993308109 NUP93 essential 0.0358506861743408 1 1 2.91672505129831 -1.0210091557342 2.06444781284932e-12 253.145911301686 61.8809275999238 4.09085514907501 7.12405138822564e-05 -205.643312777467 98.7114811441725 -2.08327653879609 0.0389937618164662 CENPT essential 2.59583667987674e-08 1 0.661895614480044 4.09085514907501 -2.08327653879609 3.75898105215282e-12 58.0934256579646 12.9180917193646 4.49705938926574 1.40750999381555e-05 -31.3940463744401 20.6067364636001 -1.52348463474043 0.129830612147214 TSNAXIP1 other 4.68744937203456e-08 1 0.140722849181679 4.49705938926574 -1.52348463474043 2.78610724306534e-06 431.5121244176 115.352780499213 3.74080384148647 0.000259977067639137 -20.9497621950732 185.667324613763 -0.112834944105832 0.910311282483 NFAT5 other 0.0243310745536896 1 1 3.74080384148647 -0.112834944105832 1.34720902827308e-12 746.52562129336 142.019709225324 5.25649309779212 5.15416234749619e-07 -200.479803260588 211.842107296025 -0.946364279602075 0.345537229864368 LONP2 other 1.70421942076545e-08 1 0.00574019060640651 5.25649309779212 -0.946364279602075 3.60519920397838e-07 269.135743502664 81.1170282493429 3.31786986420874 0.00114682781761579 -138.612552175259 120.997305906805 -1.14558378913017 0.253854603656275 N4BP1 other 0.00341628676568992 1 1 3.31786986420874 -1.14558378913017 0.000137061107513626 179.472281788847 98.2070532768759 1.82748871695457 0.0696004583109474 -239.309063973429 157.301230890493 -1.52134260246206 0.130265203457762 ARL2BP other 0.986428790775567 1 1 1.82748871695457 -1.52134260246206 3.62685871396958e-08 297.403708388858 177.473277488149 1.67576613560156 0.0958534476235842 -873.210218701592 284.264358491135 -3.07182449230202 0.00252429335344553 PLLP other 0.000372659732860374 1 1 1.67576613560156 -3.07182449230202 2.90318827436638e-13 1410.44202958297 167.606863169356 8.41518063707098 3.30632254859885e-14 1425.8204244513 249.318359415994 5.71887456580074 5.85085553643491e-08 ZNF423 other 3.7425000044857e-09 0.00085521955376069 4.56867649765389e-10 8.41518063707098 5.71887456580074 0.143441704896162 -13.5406996015613 11.8440603601847 -1.14324810831597 0.254744889166522 -37.118604855676 18.9709925227646 -1.95659793820143 0.0522395594129496 CCL22 other 1 1 1 -1.14324810831597 -1.95659793820143 1.82480527215706e-09 72.2472312989321 20.12002633005 3.59081196583863 0.000441930432108129 -52.7881276636184 31.8749362998394 -1.65610143239359 0.099724356128573 DHODH essential 2.03173819001967e-05 1 1 3.59081196583863 -1.65610143239359 1.27548025672205e-13 467.064796976882 69.3947521472421 6.73054924939945 3.93112290039264e-10 96.5949858159026 108.782946084159 0.88796074470324 0.37607408949111 CTCF other 1.6597824580724e-09 1 5.0220095052516e-06 6.73054924939945 0.88796074470324 1.81360490287611e-09 155.421359854122 40.3501350161838 3.85181759098909 0.000177335756162783 -82.5118735721326 63.9921212227289 -1.28940675813737 0.199367840443803 ACD other 2.01981178033312e-05 1 1 3.85181759098909 -1.28940675813737 1.41810603975157e-11 490.932432432431 104.615973757622 4.6927100594584 6.02558976416881e-06 -179.364864864867 162.539801323273 -1.10351349887607 0.271571420048649 POLR2C essential 1.7336346335963e-07 1 0.0623769052386755 4.6927100594584 -1.10351349887607 0.00847454753772644 26.708620653518 15.3668427264648 1.73806819845434 0.0843819402275377 -15.4712330489825 24.3705965833358 -0.634831937580121 0.526566806748354 PARD6A other 1 1 1 1.73806819845434 -0.634831937580121 3.52650444659455e-07 51.8156867475165 13.4644289050644 3.84833899104529 0.000173430012205556 -8.2484009152246 21.3308773369571 -0.386688310327196 0.699517319557585 ZNF821 other 0.00334488946759493 1 1 3.84833899104529 -0.386688310327196 1.0011544452033e-15 1403.97325665553 184.055481463696 7.62798937304379 2.67836246936088e-12 339.959216488817 289.258840034251 1.17527684356531 0.241771264394438 MMP15 other 1.35856658214088e-11 1 3.6136466436617e-08 7.62798937304379 1.17527684356531 1.16057085002852e-05 194.731835668013 82.1820571874569 2.3695176578974 0.0191014335927855 -204.579593626662 129.156091112458 -1.58397170326665 0.115334666333179 USB1 other 0.0952828667873412 1 1 2.3695176578974 -1.58397170326665 0.00215342369624945 189.336665563101 113.829792952949 1.66333137091239 0.0983202576124602 -209.329127671773 183.21598341582 -1.14252656219783 0.25504356404203 CYB5B other 1 1 1 1.66333137091239 -1.14252656219783 5.38420994832938e-05 81.5051325650236 64.3663585383024 1.26626912592115 0.207379687344961 -225.819369274253 100.539188617025 -2.24608306850821 0.026159552228844 CCDC113 other 0.408529818631769 1 1 1.26626912592115 -2.24608306850821 6.66432778852422e-05 17.8173688519429 9.06923939971384 1.96459350852566 0.0513091511114233 -21.6121218183097 14.1660021061808 -1.52563310779687 0.129206995711422 PRSS54 other 0.499891227417201 1 1 1.96459350852566 -1.52563310779687 0.00102015204626763 7.85881762160457 64.3962306561666 0.122038472462239 0.903047378601199 -435.230086008439 138.460053377565 -3.14336211341488 0.00204787993665498 NME3 other 1 1 1 0.122038472462239 -3.14336211341488 2.32824395719705e-06 198.357881792939 55.7235409478003 3.55967834095025 0.000500532863765321 -21.8573423244743 87.7303557649757 -0.249142296687236 0.803598485419625 NDRG4 other 0.020523470482692 1 1 3.55967834095025 -0.249142296687236 4.58274331324058e-12 431.691872079282 72.5819260631913 5.94764971796756 1.74249191307351e-08 4.13439953928405 122.640733872063 0.033711470966873 0.973150604628798 PSMD7 essential 5.69955785867731e-08 1 0.000209848301091442 5.94764971796756 0.033711470966873 2.48992156556564e-19 297.803478778262 59.3354551026701 5.01898027516538 1.48090542851383e-06 -292.511368504562 93.4169023915821 -3.13124671248915 0.00210056156825181 SETD6 other 3.5048135956902e-15 1 0.0160115494930915 5.01898027516538 -3.13124671248915 7.58447027928577e-06 145.805804084894 55.4503708224205 2.62948293983166 0.00946746058050859 -101.707414716434 87.6203009590607 -1.16077454200889 0.247628031290488 SLC38A7 other 0.0633303268320362 1 1 2.62948293983166 -1.16077454200889 4.04128571156894e-26 1053.57378833317 100.988232548166 10.432639147642 1.68629606371536e-19 229.710336654736 161.836251751211 1.41939975851558 0.157857275169926 VAC14 other 5.83400005322092e-22 1 2.41089748229385e-15 10.432639147642 1.41939975851558 7.61171588706121e-08 96.5349407638158 24.3845887303862 3.95885047852052 0.000115638735290881 -20.9029491361901 39.2870216472954 -0.53205736295943 0.595468227163721 HAS3 other 0.000764977446649651 1 1 3.95885047852052 -0.53205736295943 1.10296203174457e-06 29.1303563954799 11.3418951829546 2.56838525886388 0.0111808743776103 -29.7675058755352 18.3780745615149 -1.61972930166855 0.107363345108226 TANGO6 essential 0.0100259248685581 1 1 2.56838525886388 -1.61972930166855 1.14682037668587e-10 386.368825718316 85.4933371661651 4.51928581249985 1.26114160072606e-05 -128.657850916691 139.182250979074 -0.924384036122788 0.356791104852373 COG4 essential 1.35473891097902e-06 1 0.126845622201028 4.51928581249985 -0.924384036122788 0.0934236296820094 -18.8607168458783 25.6141251942055 -0.736340464602123 0.462658415822567 -81.9828673835127 41.2805599669288 -1.98599213405031 0.0488325430612211 SMPD3 other 1 1 1 -0.736340464602123 -1.98599213405031 3.35290705790129e-19 270.154900154621 37.4642940608088 7.21099668169722 2.49258517580134e-11 -30.3750205612398 61.0316940783032 -0.497692568098616 0.619424749859144 SLC7A6OS essential 4.71586377693817e-15 1 3.29843796313791e-07 7.21099668169722 -0.497692568098616 1.33876235012368e-13 263.821577787282 47.7797336697242 5.52162093683778 1.43118792247989e-07 -54.3481100108567 77.8361947442621 -0.698236985883269 0.486102890144446 SLC7A6 other 1.74079268386582e-09 1 0.00164915784307358 5.52162093683778 -0.698236985883269 0.000288296658539466 169.349310787249 60.8505694974701 2.78303575768983 0.00607363790153268 -21.2913280915878 99.1294093526008 -0.214783163045541 0.830226179969931 PLA2G15 other 1 1 1 2.78303575768983 -0.214783163045541 0.0227994701716176 2.25944504412982 22.7680082223591 0.0992377120591054 0.921080290708358 -77.9872690329543 38.3693294637017 -2.03254187975143 0.0438396791564499 FA2H other 1 1 1 0.0992377120591054 -2.03254187975143 6.48010141626943e-24 313.42536034034 38.1226179872956 8.2215067298051 8.26256725202331e-14 -105.409010095879 64.2453777813078 -1.64072519667784 0.10292217816979 WDR59 other 9.30348160333801e-20 1 1.13668137686085e-09 8.2215067298051 -1.64072519667784 1.81659366197468e-21 459.677809499092 50.9847323677327 9.01598945707154 6.9442278198104e-16 52.7321048533611 91.8101982738561 0.574359993168396 0.56655683713922 MON1B other 2.58737435275054e-17 1 9.75039028179578e-12 9.01598945707154 0.574359993168396 4.26668283672852e-06 96.4253413509796 22.7873769170833 4.23152439624112 3.97209019747401e-05 16.7137232352569 41.9868088728615 0.398070815190244 0.691129286187402 CMC2 other 0.0365782719592736 1 0.379215451152844 4.23152439624112 0.398070815190244 5.55493532910233e-13 352.519707384751 55.0267566693494 6.40633264110056 2.46134947560917e-09 -102.492842277858 120.175489839648 -0.852859783759704 0.39529370687167 AXIN1 ts 7.10865074065225e-09 1 3.06561077187123e-05 6.40633264110056 -0.852859783759704 1.46089409842455e-05 467.52534909632 129.600123516181 3.60744524319799 0.000421381684475554 -272.452364114299 277.722976645641 -0.981022050840009 0.328172086608966 HCFC1R1 other 0.118522338205184 1 1 3.60744524319799 -0.981022050840009 6.39095545316357e-16 728.437788532191 91.2504348960322 7.98284182822963 6.82438132348002e-13 -6.23931385714693 200.582921563059 -0.0311059077638642 0.975233153067929 NPRL3 other 8.7051204227541e-12 1 9.29207761005039e-09 7.98284182822963 -0.0311059077638642 8.08668514199581e-17 106.920001071295 15.6768373739358 6.82025325140257 1.91598037180729e-10 -28.4040022594577 29.0324522340388 -0.978353534537319 0.329424025823882 MLYCD other 1.11402174516134e-12 1 2.4756382384122e-06 6.82025325140257 -0.978353534537319 0.000781743818664454 3.29847214128233 72.0958369081702 0.0457512150872686 0.963579291874346 -507.603238148327 158.478078663967 -3.20298707826106 0.00171347641414014 MPG other 1 1 1 0.0457512150872686 -3.20298707826106 0.913075947054096 1.58299855375221 5.0630998941179 0.312654023593583 0.754963781073352 -0.211415131550132 9.37652170051446 -0.0225472876086376 0.982040391630684 NECAB2 other 1 1 1 0.312654023593583 -0.0225472876086376 1.01469525013376e-19 311.059322941775 32.3981725021498 9.60113793212056 2.0307042631498e-17 137.102155250074 59.999244312035 2.28506470076612 0.0236651901907013 HSDL1 other 1.43153205888871e-15 1 2.87689872960433e-13 9.60113793212056 2.28506470076612 9.19173677596361e-10 276.013980395308 57.86779851707 4.76973355594111 4.22395155040215e-06 -83.8658495610121 107.167284845925 -0.782569509730386 0.435073893262961 TAF1C essential 1.03958542936148e-05 1 0.0443092517637185 4.76973355594111 -0.782569509730386 3.5212493539866e-26 147.73188025407 11.1918936576195 13.1999002826026 4.31706688664046e-27 70.346333055866 35.7628419771409 1.96702300954802 0.0509775199285717 NAGPA other 5.08362769235046e-22 1 6.25283967861005e-23 13.1999002826026 1.96702300954802 0.952797184426727 -1.39464750699203 12.8075509728127 -0.108892598589107 0.913428520204083 3.64642684926215 23.5960060659285 0.154535765038958 0.877388353349883 WFDC1 other 1 1 1 -0.108892598589107 0.154535765038958 8.1037389018859e-07 9.48197961739498 1.7256926073727 5.49459363555537 1.58663087334681e-07 11.2603331608536 5.51431901576134 2.04201699768706 0.0428560231430651 SEC14L5 other 0.00744895679861352 1 0.00182367352582483 5.49459363555537 2.04201699768706 0.366683244751854 -213.504590606616 177.840295748275 -1.20054113556369 0.231760790149546 -59.6720705950435 327.64427064554 -0.182124566004083 0.855722941390151 COTL1 other 1 1 1 -1.20054113556369 -0.182124566004083 5.48544654075037e-24 749.740525227777 72.7364159924027 10.3076363469172 2.67101424926258e-19 157.416985682567 133.857332296925 1.17600569936192 0.241395672627374 USP10 essential 7.87710123251752e-20 1 3.8166122607713e-15 10.3076363469172 1.17600569936192 0.315836817641818 -91.9598614194931 128.784778720038 -0.714058465087727 0.476264929288308 139.307360653855 237.003524090528 0.587786030559798 0.557531287471742 CRISPLD2 other 1 1 1 -0.714058465087727 0.587786030559798 5.42580876858795e-16 1540.74972790285 201.385303024693 7.65075556538466 3.10200478679264e-12 -303.918447232248 424.93194099335 -0.715216762763908 0.475683398429678 TSC2 ts 7.3937496089548e-12 1 4.17840044780968e-08 7.65075556538466 -0.715216762763908 1.68911482918272e-16 160.401407849101 17.652055260162 9.08684034153815 4.36132279954942e-16 -40.9798732252387 55.6308560644438 -0.736639270439536 0.462448094217803 ZNF500 other 2.31678989970702e-12 1 6.13027532704666e-12 9.08684034153815 -0.736639270439536 0.00133144752829811 561.088492827724 217.793323116508 2.57624285629533 0.0110964447358937 -365.947797866509 475.648954682258 -0.769365294013879 0.443061487392404 NME4 other 1 1 1 2.57624285629533 -0.769365294013879 1.92669020997012e-06 364.491195476575 78.3497762482346 4.65210257042422 7.02874895764741e-06 13.6332794830369 192.199233914189 0.0709330583967037 0.943543064745239 ABCC1 other 0.0171167158253746 1 0.0722695967825307 4.65210257042422 0.0709330583967037 1.11181270320108e-05 318.491501340688 78.7371604709563 4.04499602774181 8.25116551289909e-05 -105.051810882868 195.207527236992 -0.538154508536598 0.591247313882824 NOMO3 other 0.0914577129653208 1 0.761500065185457 4.04499602774181 -0.538154508536598 0.141992542161438 8.20635619707909 18.3249206119186 0.447824924913542 0.655008140432724 -53.4734566498078 39.1310404457568 -1.3665227410432 0.17408071104378 LMF1 other 1 1 1 0.447824924913542 -1.3665227410432 0.614856317781449 -4.85286164435607 5.83945306931637 -0.831047289318175 0.4072419375043 -9.45798042326863 10.0668585306974 -0.939516572566102 0.348946461126286 FOXF1 other 1 1 1 -0.831047289318175 -0.939516572566102 6.21214166368247e-07 78.7335506459009 32.4343833186236 2.42747179351157 0.0165633850130814 -197.946637691658 69.3736101255493 -2.85334203212753 0.00502993765733035 NARFL essential 0.00576610989223007 1 1 2.42747179351157 -2.85334203212753 7.56809712535649e-16 104.717791136836 17.360947544853 6.03180159759664 1.17057275088689e-08 -52.4530108163675 29.9292075504862 -1.75256931637388 0.0816791037182487 MTHFSD other 1.02926120904848e-11 1 0.000142107531957669 6.03180159759664 -1.75256931637388 3.64051521816832e-08 600.022928758211 111.153808556965 5.39813198079224 2.8844088766571e-07 14.8026716139619 245.882892031828 0.0602021209838616 0.952082387757344 CLCN7 other 0.000374026533514613 1 0.00325909358973486 5.39813198079224 0.0602021209838616 0.00174956254901938 2.24272606543501 41.1598530119467 0.0544881942310158 0.956629225058802 -263.010692080164 88.0364386036022 -2.98752080674698 0.00335856398761718 HAGHL other 1 1 1 0.0544881942310158 -2.98752080674698 0.0251661576174556 25.1149342025835 32.9127462492433 0.7630762262253 0.446789910360033 -123.670786550767 70.3967762860193 -1.75676775380022 0.0812939050718644 FAM173A other 1 1 1 0.7630762262253 -1.75676775380022 0.496133346574554 -75.3313058218553 181.699054653388 -0.414593823647342 0.679023799452451 -353.6126237518 314.84548021714 -1.12313069734374 0.263152807004582 SLC7A5 essential 1 1 1 -0.414593823647342 -1.12313069734374 0.0113646843926939 177.769588313412 145.858339455128 1.21878247741948 0.225116977010095 -505.52099933599 311.975087533419 -1.62038899750878 0.10755347506696 METRN other 1 1 1 1.21878247741948 -1.62038899750878 3.28512300924377e-10 82.5378627085086 17.6603259223791 4.67363190641441 6.47315767215002e-06 -36.427545191664 30.6015559983487 -1.19038212284465 0.23575203871516 FBXO31 other 3.80154434629689e-06 1 0.0668094603342604 4.67363190641441 -1.19038212284465 1.44290774646515e-06 510.409211638294 143.230576429291 3.5635492390151 0.000511118569108941 -434.819049559339 306.354588883394 -1.4193325817125 0.158177191925722 STUB1 other 0.0129760693639611 1 1 3.5635492390151 -1.4193325817125 0.00826017135158835 8.47358598400747 10.9096959362311 0.776702305319683 0.438734618709169 -48.4492481678358 23.4203683288142 -2.06868002619021 0.0405427541416884 RHBDL1 other 1 1 1 0.776702305319683 -2.06868002619021 3.32979242577259e-06 71.7645082349285 20.2035233714451 3.55207885850039 0.000507487853706299 -62.7719585146057 44.1087828376597 -1.42311699567034 0.156724904511924 NUBP1 essential 0.0288393321996164 1 1 3.55207885850039 -1.42311699567034 3.26264061811042e-07 433.942746923676 122.573303187126 3.54027129595423 0.0005477915085888 -487.139298233026 266.766116894149 -1.82609134887366 0.0700298739173398 UBE2I essential 0.00310342375594663 1 1 3.54027129595423 -1.82609134887366 0.882514297347935 -3.70302325581393 13.6326452235539 -0.271629107564247 0.786264063863756 -18.3118604651162 36.9173777843096 -0.496022782877581 0.620572015263408 CRYM other 1 1 1 -0.271629107564247 -0.496022782877581 1.31304163746352e-05 258.560811665158 89.4991508053239 2.88897502756839 0.00452427127035651 -318.254277578559 192.132126250707 -1.65643447448908 0.100027200850893 CAPN15 other 0.107209849698896 1 1 2.88897502756839 -1.65643447448908 1.18203370369755e-10 832.76447132986 132.2496529816 6.29691233628965 2.98301211219758e-09 45.0777200864893 298.768724567097 0.150878309474343 0.880267888432693 GSPT1 essential 1.39550899058532e-06 1 3.70281293487086e-05 6.29691233628965 0.150878309474343 2.13311091710529e-07 51.7562799693901 12.340666217561 4.19396157848756 4.62534336579023e-05 -28.0118754256267 25.4558713517267 -1.10040921556302 0.272882163252221 ZNF174 other 0.00206549130103305 1 0.439130099148124 4.19396157848756 -1.10040921556302 9.9106959915271e-08 122.715997613868 33.3079165289913 3.68428921415891 0.000317686768092157 -134.645325987789 68.5390166780264 -1.96450624058859 0.0512830399500409 CLUAP1 other 0.000986510678996608 1 1 3.68428921415891 -1.96450624058859 1.93902622157839e-13 710.758321769372 95.2631553949515 7.46099915358293 5.62561540490013e-12 86.7289407411213 194.331572025965 0.446293619904096 0.656004028261134 UBFD1 other 2.51123285956617e-09 1 7.54057488872814e-08 7.46099915358293 0.446293619904096 4.48616965275967e-05 445.131572451247 111.695930508254 3.9852085069326 0.00010519796709689 8.97543816341685 239.355684688711 0.0374983287950302 0.970137865591162 PRSS33 other 0.343416286918753 1 0.960141845693317 3.9852085069326 0.0374983287950302 9.44748573146391e-15 181.838092301216 28.7890401299413 6.31622629585695 2.66699406996542e-09 -129.925983303842 58.7280507597648 -2.21233263530782 0.0283966516042225 EARS2 essential 1.26057802114923e-10 1 3.31774062303698e-05 6.31622629585695 -2.21233263530782 0.000116584604083994 796.603461274159 349.623859874554 2.27845851699018 0.0241206447742225 -1526.96832780695 749.216717054876 -2.0380863013967 0.0433101008890424 ELOB other 0.848386163919222 1 1 2.27845851699018 -2.0380863013967 0.000133472709074637 236.681054926982 73.3261756593137 3.22778397753408 0.0015207223972105 -127.501082974178 149.581345772656 -0.852386253884644 0.395306474177479 GGA2 other 0.962738650555353 1 1 3.22778397753408 -0.852386253884644 0.0173146238600217 67.7080894280274 38.548506224782 1.75643873288401 0.0809757399423482 -87.2698537562774 86.8610855108194 -1.00470599973572 0.31659430706295 CPPED1 other 1 1 1 1.75643873288401 -1.00470599973572 0.0288904489612417 75.2333739887274 31.5997726756532 2.38082010149057 0.0184807978071732 10.4447651970584 64.2575199177324 0.16254541430218 0.871086727311811 USP31 other 1 1 1 2.38082010149057 0.16254541430218 2.10101260820096e-20 259.903275456127 24.278911653142 10.7048981094872 2.28423495474826e-20 -1.50968588472021 76.7931893582965 -0.0196591116651819 0.984340592464797 HMOX2 other 2.97419344816928e-16 1 3.27330869015426e-16 10.7048981094872 -0.0196591116651819 2.272589302729e-22 555.300506668221 48.3513643681623 11.4846915681632 1.77187347924915e-22 42.9549406391177 152.933357668681 0.280873586338021 0.779181928800251 DNAJA3 essential 3.24503026536674e-18 1 2.55132062277085e-18 11.4846915681632 0.280873586338021 3.16652182589094e-25 338.40617814286 26.848268511317 12.6043948793278 1.96120849914258e-25 57.8488242847248 85.5737782153213 0.676011103999232 0.500054154676354 CORO7-PAM16 other 4.56359125547402e-21 1 2.83394628126103e-21 12.6043948793278 0.676011103999232 4.68676201426614e-13 365.183855641144 55.0143476955392 6.637974836349 5.04983736415334e-10 -81.2459217562416 126.045572502619 -0.644575768455122 0.520154944041145 BFAR other 6.0103036070949e-09 1 6.4350077531406e-06 6.637974836349 -0.644575768455122 2.68676629080064e-07 281.688628464697 48.6314833180298 5.79231002728356 3.97904798882638e-08 290.070826798647 72.3267223080454 4.01056231420541 9.55059809174958e-05 SALL1 other 0.00257499681310333 1 0.000471795720035143 5.79231002728356 4.01056231420541 0.282225102419732 37.7369700642166 45.6425621447195 0.826793420241472 0.409676233726757 -29.6101254036639 69.852047130287 -0.423897747025732 0.672251720336472 TOX3 other 1 1 1 0.826793420241472 -0.423897747025732 0.00136811987776741 20.8791090027952 6.35254572382483 3.28673100682918 0.00125883944087984 -0.435761373467304 13.9328974685691 -0.0312757180945548 0.975090684518423 RRN3P2 other 1 1 1 3.28673100682918 -0.0312757180945548 3.29360020095408e-12 548.74263124237 102.499893918607 5.35359218691598 3.14747225442201e-07 -74.7052642288237 157.271416663124 -0.47500852865618 0.635467222200504 RBL2 ts 4.11436537103183e-08 1 0.00355034870298802 5.35359218691598 -0.47500852865618 0.428418401500475 -17.431155451933 14.2338067312742 -1.22463061224751 0.222584407246321 -8.416537439679 30.6568867687024 -0.274539861244862 0.784037718153363 XYLT1 other 1 1 1 -1.22463061224751 -0.274539861244862 0.000787577878693265 -191.188441843453 59.2482525097635 -3.22690431775937 0.00153671123522983 -410.676420385272 122.755214968561 -3.34549062123716 0.00103789324316798 PYCARD other 1 1 1 -3.22690431775937 -3.34549062123716 1.52733465858279e-13 94.1410205609122 19.5244530226942 4.82169822895872 3.44147674771869e-06 -49.6509708096684 29.7085157657958 -1.67127066195723 0.096739422040011 RPGRIP1L other 1.98385498803319e-09 1 0.0363006967349367 4.82169822895872 -1.67127066195723 4.40235639067891e-06 1627.21296435112 369.670564499852 4.40179208358846 2.02818348440854e-05 -349.368373709137 790.591343587462 -0.441907663855526 0.659192463982562 MAZ other 0.0376445494966954 1 0.199999173397526 4.40179208358846 -0.441907663855526 0.0257077654357352 31.055324901033 30.0136976957338 1.0347050608645 0.302460924769633 -113.239367899327 62.152070985929 -1.8219725602541 0.0704379035163372 STX4 other 1 1 1 1.0347050608645 -1.8219725602541 2.17953230552048e-06 439.005355708292 131.323064131157 3.34294176436397 0.00104373353339996 -620.252924763817 280.552166832007 -2.21082920787142 0.0285413418410841 CDIPT essential 0.0192712846116874 1 1 3.34294176436397 -2.21082920787142 0.000359197164443623 142.93328456474 84.8046938240414 1.68544072408667 0.09398277680259 -456.88378444282 175.705071115772 -2.60028797997401 0.0102460606029685 BCKDK other 1 1 1 1.68544072408667 -2.60028797997401 1.36380727969976e-10 285.016093635699 54.1112097435486 5.26722826908671 4.72587482844541e-07 -245.484467203121 112.111883522364 -2.18963823896646 0.0300956276593885 KAT8 essential 1.60479202602271e-06 1 0.00527502148351077 5.26722826908671 -2.18963823896646 4.28967188887209e-10 750.617404252085 118.761738945249 6.32036387239269 2.61076681451679e-09 121.67195966797 308.029581696287 0.395000892440053 0.693381792886226 NOMO1 other 4.93483854095845e-06 1 3.24909930066615e-05 6.32036387239269 0.395000892440053 0.509833864170551 -5.17475588742107 12.395279820974 -0.41747794016436 0.676914102139405 -29.1958165805093 25.38726274038 -1.15001829378288 0.251930697835534 IL21R other 1 1 1 -0.41747794016436 -1.15001829378288 0.00109428758772508 85.2141343158316 37.0963769495148 2.29710126225538 0.0229341908555992 -100.810793253386 76.1230829916363 -1.32431306367955 0.18732374664441 SYT17 other 1 1 1 2.29710126225538 -1.32431306367955 0.107469573601472 -89.1633569000097 46.5165566564822 -1.91680905270929 0.05707862207748 -171.56993660232 95.4536263114196 -1.79741664337162 0.0741914070831864 TMC5 other 1 1 1 -1.91680905270929 -1.79741664337162 3.92175183647765e-05 92.5387712135653 27.6140409442433 3.35114919980072 0.00100820084635133 -54.7263657529244 56.6649927402297 -0.965787924897606 0.335635622859687 CCP110 other 0.302249414037332 1 1 3.35114919980072 -0.965787924897606 1.62818317526311e-09 221.436698115899 53.0575436584797 4.17351959489947 4.95309554036228e-05 -248.260692580581 109.490631963316 -2.26741492060945 0.0247292725977739 C16orf62 other 1.81737806022869e-05 1 0.46881049289529 4.17351959489947 -2.26741492060945 1.69306735669932e-09 698.083868730938 113.81422298902 6.13353806227089 7.02225476244432e-09 36.2665635757807 234.771121058871 0.15447625505305 0.877437817610185 RNF40 essential 1.88895524986944e-05 1 8.607177662328e-05 6.13353806227089 0.15447625505305 5.31766942313259e-16 256.433376449217 38.685649979923 6.62864334920829 5.14909304418357e-10 -164.938046279828 79.8324983055724 -2.06605141741274 0.0404666637135816 KNOP1 other 7.24851519067203e-12 1 6.55994453828987e-06 6.62864334920829 -2.06605141741274 0.346937161711817 -159.6040012447 112.608426220664 -1.41733622075443 0.158404652632868 -166.117086470662 179.555712839818 -0.925156230583734 0.356332101689869 AQP9 other 1 1 1 -1.41733622075443 -0.925156230583734 3.28273873192634e-07 292.229123814316 51.6286265218037 5.66021495247219 7.12607969960052e-08 115.428385397399 86.986340554405 1.32697139184979 0.186469621077761 AAGAB other 0.00312188453406195 1 0.000834178889635237 5.66021495247219 1.32697139184979 0.00255951077724785 17.917479319887 5.99515649569694 2.98865915055718 0.00325921168338284 -5.63830149311155 10.1009219060168 -0.558196721603499 0.577515459234763 IQCH other 1 1 1 2.98865915055718 -0.558196721603499 0.537779446447152 15.343913947273 14.5675682869026 1.05329274214341 0.293878328916908 3.10409256387422 23.8699831941408 0.130041673621126 0.896705391256172 LACTB other 1 1 1 1.05329274214341 0.130041673621126 0.165557492296149 87.1955350994279 55.0836995547646 1.58296439426218 0.115481097085865 146.8710008548 92.9906027676014 1.57941766677063 0.116292099358379 CORO2B other 1 1 1 1.58296439426218 1.57941766677063 1.33137641664281e-12 522.902197642266 81.8690841353016 6.38705322241162 2.00735574586653e-09 -270.756294571386 140.174151026928 -1.93157078240033 0.0552978433214713 CSK other 1.68459057997815e-08 1 2.50919468233316e-05 6.38705322241162 -1.93157078240033 4.4816389839384e-10 312.82629132285 45.6399956142362 6.85421387782236 1.6243657463185e-10 110.517233168025 74.7934785572431 1.47763194465465 0.141548535641887 HERC1 other 5.14895502864682e-06 1 2.1032287683332e-06 6.85421387782236 1.47763194465465 5.61454114294415e-05 88.7622582391444 22.3856471953081 3.96514147948103 0.000111737886825747 -14.5080956052429 36.1456091621807 -0.401379197681989 0.688693789248338 TRIP4 other 0.424852328286584 1 1 3.96514147948103 -0.401379197681989 1.11157861757802e-06 57.1183132796957 13.181261307626 4.33329648405118 2.63045843235875e-05 -29.1375071120089 21.7400761349438 -1.3402670225784 0.182119839548096 MTFMT other 0.0101031380551666 1 0.256496001739302 4.33329648405118 -1.3402670225784 2.14631211678967e-06 97.7384384510522 18.3820930322565 5.31704622969447 3.62121855119084e-07 75.4640447378773 30.3178954361273 2.48909245355973 0.013863357885174 RASL12 other 0.018990569609355 1 0.00406880116411803 5.31704622969447 2.48909245355973 0.000709263061132843 57.6026570520081 15.8064248928417 3.64425589230457 0.000368957746992203 0.486105360198203 27.6250543368456 0.0175965395134028 0.985984101283494 AP3B2 other 1 1 1 3.64425589230457 0.0175965395134028 0.000363955921189901 130.479858431671 56.1344467732082 2.32441692992593 0.0214270293445811 -219.401954544174 100.854715793146 -2.17542583724266 0.0311435156140302 ACSBG1 other 1 1 1 2.32441692992593 -2.17542583724266 0.839565138703598 11.3776044393257 20.2021200892527 0.563188635106594 0.574120226496308 13.0403491780966 33.5752569148599 0.388391642427764 0.698259171876884 IGDCC4 other 1 1 1 0.563188635106594 0.388391642427764 1.54410981371351e-11 924.974611173737 152.958959580957 6.04720778506715 1.04813725472213e-08 -487.708209004708 254.6228108804 -1.91541444114287 0.0572691947853563 RAB11A other 1.88566690450694e-07 1 0.000127432527429117 6.04720778506715 -1.91541444114287 0.38086274532409 36.6752862982782 122.623574562631 0.299088380265298 0.765281152065687 -249.770734792912 218.919065329136 -1.14092728478167 0.255694578695786 CTSH other 1 1 1 0.299088380265298 -1.14092728478167 1.1391066920109e-09 96.4363661612653 16.0168553040132 6.02093009712724 1.22227542253989e-08 -41.2321941817846 32.0365901721123 -1.28703441784129 0.200013416800551 TTC23 other 1.28206458185826e-05 1 0.000148237563245637 6.02093009712724 -1.28703441784129 0.000101986323473861 816.380394186602 184.660733582198 4.4209744992874 1.87525949787802e-05 507.69399858449 321.958474326732 1.57689279540215 0.116926853953858 CD276 other 0.7475597510634 1 0.1854069065552 4.4209744992874 1.57689279540215 0.0367082016881656 135.898040425196 63.8699651239863 2.12772999267162 0.0349516079416754 -64.9800205138504 113.316897988193 -0.573436280620926 0.567185778711763 FAH other 1 1 1 2.12772999267162 -0.573436280620926 0.00829769965100505 436.289175993635 146.373500847994 2.98065683655891 0.00334708480173049 532.402554517811 259.498752862789 2.05165746904117 0.041907918110136 CEMIP other 1 1 1 2.98065683655891 2.05165746904117 1.13274001063217e-19 471.691246551291 48.5052933695556 9.72453136109364 1.23637373494119e-17 72.938765694389 71.279936730437 1.02327203193551 0.307826678100497 RPAP1 essential 1.59750323699455e-15 1 1.7533015935201e-13 9.72453136109364 1.02327203193551 0.161675481838488 391.898017164504 233.269443906194 1.6800229408619 0.0950205681755217 -99.6029279502446 408.178581012057 -0.244018017073029 0.807548100580862 HOMER2 other 1 1 1 1.6800229408619 -0.244018017073029 0.00783497288861999 163.461757546252 111.753247362662 1.46270252904405 0.145839121085039 -273.355459730143 173.881162814065 -1.57208207781799 0.11823817501469 EHD4 other 1 1 1 1.46270252904405 -1.57208207781799 1.02249228275243e-12 366.12627986348 74.3731936347996 4.92282584584572 2.36565933168009e-06 -337.937411394067 114.458431644427 -2.95249031931429 0.00369775940502359 TMEM87A other 1.29784945449766e-08 1 0.0252368537503632 4.92282584584572 -2.95249031931429 6.7806195077964e-10 414.993624641833 72.3399423484068 5.73671489317924 5.72469919889938e-08 -43.955405053399 111.197792976629 -0.395290265002268 0.693230338077849 ZNF106 other 7.71770112377386e-06 1 0.000673797095710457 5.73671489317924 -0.395290265002268 3.41024648203743e-05 34.4873908826383 10.8397964435243 3.18155336793627 0.00178287287430989 -24.6028128031038 16.2802116383255 -1.51120964209003 0.132852979167465 CEP152 other 0.265555893556254 1 1 3.18155336793627 -1.51120964209003 0.284013325098229 -9.78354249753028 6.48867674871849 -1.50778700749155 0.133698411553701 -2.34725612465175 9.79534812299094 -0.239629678820954 0.81094232595755 ATP8B4 other 1 1 1 -1.50778700749155 -0.239629678820954 0.350025392043761 4.28316297953388 12.232896809361 0.350134808319176 0.726728690189368 -16.9309804028066 17.2241510377313 -0.982979095208671 0.327200565325753 OCA2 other 1 1 1 0.350134808319176 -0.982979095208671 4.69751501116825e-12 89.4087280243829 17.8412877859329 5.01133825636051 1.48523381330622e-06 -78.6075763807595 26.7843872493072 -2.93482825084202 0.00385552346042203 DTWD1 other 5.83901115888213e-08 1 0.0160524070542136 5.01133825636051 -2.93482825084202 0.397594018638711 16.2210914733718 21.8028924312225 0.743988052252304 0.458017368235399 -17.1626473958192 31.7451886582892 -0.540637750827725 0.589538380212393 FAM189A1 other 1 1 1 0.743988052252304 -0.540637750827725 4.71651374455324e-12 1192.41615728779 184.523237207994 6.46214631463302 1.28734793098345e-09 -57.7657122034485 279.782299224972 -0.20646664339905 0.836699137308475 TJP1 other 5.86168328173077e-08 1 1.61858255362549e-05 6.46214631463302 -0.20646664339905 0.000380843068664248 405.266784044334 106.572467974427 3.80273434356031 0.000205830279478572 484.654984702419 150.827555142167 3.2133053157667 0.00159830331728545 BMF other 1 1 1 3.80273434356031 3.2133053157667 9.10960884393905e-09 184.18844381959 29.6149951842186 6.21943183423989 4.488764911823e-09 53.1200557347829 44.0561017098911 1.20573663290905 0.229768333869775 DMXL2 other 9.73817185417085e-05 1 5.53734039522485e-05 6.21943183423989 1.20573663290905 0.358892729299806 -26.9702572084908 35.0293316036197 -0.769933537804183 0.442518746650412 38.3863349359175 52.1106212024964 0.736631689473673 0.46246704187825 SCG3 other 1 1 1 -0.769933537804183 0.736631689473673 3.44461993906083e-05 110.607277822598 47.4504757405184 2.33100461262919 0.0210847396804115 -174.21953607565 74.4158350014306 -2.34116214744216 0.0205399034350378 DNAJC17 essential 0.267991431258933 1 1 2.33100461262919 -2.34116214744216 1.40261230264354e-14 359.009123825913 65.928877396034 5.44540022529657 2.23459043735889e-07 -357.248046174805 104.218100282418 -3.42788867966991 0.000797636016181039 EIF3J other 1.86575488497643e-10 1 0.00254363429484563 5.44540022529657 -3.42788867966991 3.04131877374979e-15 539.717980553434 72.536142755047 7.4406766069165 8.7524698184094e-12 -113.273121920003 114.372796402506 -0.990385174472496 0.323670491299294 SPG11 other 4.09300680571247e-11 1 1.16784204787037e-07 7.4406766069165 -0.990385174472496 0.239431251848337 24.7680350028459 32.9135641086756 0.752517561485155 0.452927083554936 -48.6411496869659 51.6345139759023 -0.942027840325303 0.347703230102319 RHOV other 1 1 1 0.752517561485155 -0.942027840325303 1.07868520570705e-11 295.180077279097 42.4569858275566 6.95245014514222 1.03017343371593e-10 36.7924729061084 66.5846232876359 0.552567110685154 0.581382336821836 VPS18 essential 1.3248411696494e-07 1 1.34200693210174e-06 6.95245014514222 0.552567110685154 0.00054937940176378 30.3288755759587 11.5865948033767 2.61758317181505 0.00975075070798593 -19.1879357698257 17.0113951974836 -1.12794603541185 0.261119980469129 OIP5 essential 1 1 1 2.61758317181505 -1.12794603541185 0.00268762842495585 21.0182191310775 9.04558617093012 2.32358840365967 0.0215979389643575 -15.856774270179 13.9609198807106 -1.13579724012942 0.257995978546736 SLC30A4 other 1 1 1 2.32358840365967 -1.13579724012942 2.64634246092339e-09 198.214986077374 41.7447359470191 4.74826302240698 4.87764140276118e-06 -119.266784169678 62.9132809070043 -1.89573302250717 0.0599851541009329 BLOC1S6 other 2.92156207685942e-05 1 0.0508835551136046 4.74826302240698 -1.89573302250717 1.61413052277703e-08 351.944837738596 72.7489818321765 4.83779743544029 3.24398857743744e-06 -143.013982158413 108.884144240097 -1.31345094509865 0.191049985957949 MYEF2 other 0.000169967944048422 1 0.034275983309204 4.83779743544029 -1.31345094509865 0.0127539928872965 25.5648840294049 11.7076344581897 2.18360797996402 0.0305879473206228 -43.9973223251143 41.2696221682886 -1.06609462392708 0.28814066894213 SGK3 other 1 1 1 2.18360797996402 -1.06609462392708 0.00179503167252063 184.311848450058 58.0929282990267 3.17270714089903 0.00182556788936125 109.440821533359 109.719712924676 0.997458146910131 0.320117086222532 PDGFRL other 1 1 1 3.17270714089903 0.997458146910131 3.17760889122173e-05 68.087248074415 23.5365979811623 2.89282453347375 0.00439878199585096 -193.971257720797 82.9407486628339 -2.33867261687398 0.0206994987623722 CSPP1 other 0.248393687026803 1 1 2.89282453347375 -2.33867261687398 7.3033872156347e-12 303.136587831774 65.0151211619397 4.6625551473898 6.75399853986718e-06 -144.949958897508 128.187660857198 -1.13076374066131 0.259923945969501 ZDHHC2 other 9.02041355003042e-08 1 0.0695932009547914 4.6625551473898 -1.13076374066131 5.50439680919994e-20 161.264349908438 14.6876694722712 10.9795737310734 1.7853396002199e-20 68.5805817720805 50.1695994137453 1.36697487270132 0.173888502382511 BRF2 essential 7.77716225171859e-16 1 2.55999845275531e-16 10.9795737310734 1.36697487270132 2.82158498396277e-14 57.6020437666769 16.3098525348913 3.53173295978305 0.000544050711281383 -105.332952639796 33.2587746202908 -3.16707256483027 0.00185472844998343 TRIM35 other 3.73041750729718e-10 1 1 3.53173295978305 -3.16707256483027 4.4620267705482e-05 163.942764344021 49.1542804646026 3.33526933553795 0.00106939330819122 -226.375060021563 152.951950592719 -1.48004036002362 0.140918658270117 ZFAND1 other 0.341746630356287 1 1 3.33526933553795 -1.48004036002362 0.353933145540243 4.43470325055466 21.2239166282262 0.208948391959702 0.83477013539858 -85.4346809915637 71.1533075303931 -1.20071271395318 0.231742833638813 CA2 other 1 1 1 0.208948391959702 -1.20071271395318 1.27491791156616e-14 854.735377005809 135.210710574523 6.32150643520738 2.73399414661219e-09 105.437620060968 251.475394129389 0.419276090314895 0.675606309750575 FZD3 other 1.69691574029456e-10 1 3.39999512072692e-05 6.32150643520738 0.419276090314895 9.96849895741659e-24 180.089406163206 26.5936265436045 6.77190099920823 2.60618207280855e-10 -99.5018677717528 48.6972973526238 -2.04327289564442 0.0427525206088545 INTS9 essential 1.43037991539971e-19 1 3.35024705459539e-06 6.77190099920823 -2.04327289564442 0.0137646599667862 168.114730189596 62.5516788579028 2.68761339837894 0.00801507084456124 526.466212931453 257.345498362989 2.04575644913309 0.0425390579614256 RIPK2 other 1 1 1 2.68761339837894 2.04575644913309 0.954027587050684 4.30806197600631 23.2855002132767 0.185010497371664 0.853472394486329 23.011348371856 76.8499320363692 0.299432254032 0.765027528510953 EYA1 other 1 1 1 0.185010497371664 0.299432254032 2.36428464523865e-09 243.984371226578 38.5134326626819 6.33504609582594 2.6570476798578e-09 -29.4404018353927 158.394447077881 -0.18586763853481 0.852801356210018 NBN ts 2.61560810302752e-05 1 3.3056330185111e-05 6.33504609582594 -0.18586763853481 0.773268701395283 -0.7041247735105 4.3414301740165 -0.162187285131221 0.871381094913036 8.13682038346302 14.2807887336707 0.569773878404792 0.569700790537529 TRPA1 other 1 1 1 -0.162187285131221 0.569773878404792 0.099020026791384 57.9733666504145 27.793411864972 2.08586721673701 0.0386614529591163 4.83093612871789 127.840922510094 0.0377886519735999 0.969905776940082 CPQ other 1 1 1 2.08586721673701 0.0377886519735999 0.0141683534859934 62.0770879009001 36.231805492341 1.71333134127204 0.0887314048608947 -259.747304445003 149.010784051806 -1.74314433749101 0.0833712536242168 DECR1 other 1 1 1 1.71333134127204 -1.74314433749101 0.0856345724009404 89.3801522904805 41.3406131610839 2.16204224988658 0.0322220175086103 26.3355241198634 169.67336979821 0.155213067030989 0.876864831208407 CALB1 other 1 1 1 2.16204224988658 0.155213067030989 0.22187491730434 156.414688014292 176.741226778304 0.884992657714724 0.377846331653586 880.835924292202 504.865335184667 1.74469479860409 0.083476296957202 SFRP1 other 1 1 1 0.884992657714724 1.74469479860409 2.31495232549008e-09 4571.96857142857 721.275513598825 6.33872699853153 2.53693742424747e-09 -1267.57436520926 3335.17532798231 -0.380062287752682 0.704433227182941 LAPTM4B other 2.56149474815477e-05 1 3.15874078693053e-05 6.33872699853153 -0.380062287752682 1.45110769571868e-05 136.953366663832 37.2535204536423 3.67625300900767 0.000331115125408003 -196.860634575431 125.620243462261 -1.56710916289995 0.119239317184968 UBE2W other 0.117757389507571 1 1 3.67625300900767 -1.56710916289995 0.00750432987358093 18.1854999509692 5.8175517203022 3.12597134074547 0.00212361070600038 9.89099316334305 25.9265259403991 0.38150090706641 0.703364361862654 POP1 essential 1 1 1 3.12597134074547 0.38150090706641 0.012649549032938 88.809008596738 35.9322023168238 2.47157153946995 0.0145553626440355 -141.502852588199 160.135606910325 -0.883643902304871 0.378283965864837 NIPAL2 other 1 1 1 2.47157153946995 -0.883643902304871 1.16751051833259e-07 189.942353479006 39.48717158133 4.81022939533135 4.65203689151921e-06 -127.155073501627 115.711499197883 -1.09889746812608 0.27412815993022 IKBKB other 0.00115513490683827 1 0.0486370457008334 4.81022939533135 -1.09889746812608 0.00168313930653758 1079.63413551359 296.047359066167 3.64682913882129 0.000401636379329968 1083.45544847487 867.524372581721 1.24890491001486 0.214258347624216 PLAT other 1 1 1 3.64682913882129 1.24890491001486 0.117365522428769 12.8543495610534 6.99392371810704 1.8379310497445 0.0680508566628217 -4.86495939157801 23.6451836588736 -0.20574842901473 0.83726640042662 JPH1 other 1 1 1 1.8379310497445 -0.20574842901473 6.29825102939666e-14 189.05737815126 23.2471644926249 8.13249195235136 1.42203070786302e-13 -38.1841318681319 102.618637246896 -0.372097436611464 0.710341986999488 STK3 other 8.26330535056841e-10 1 1.95145274040042e-09 8.13249195235136 -0.372097436611464 0.922488279703896 -2.81299661118888 11.7027862930287 -0.240369817986385 0.810367457671192 -15.4023374700732 39.5423966889263 -0.389514515046747 0.697440774086452 GDAP1 other 1 1 1 -0.240369817986385 -0.389514515046747 8.31444825952242e-06 575.745833845146 122.354505926937 4.70555480963611 5.97962210446066e-06 -222.33536011137 504.126094925718 -0.44103124664501 0.659865877983602 RAB2A other 0.0692593540018218 1 0.0619189868916902 4.70555480963611 -0.44103124664501 0.000478098297018538 1236.3702007189 367.644900318148 3.36294669026819 0.000975848483382397 -1644.92533296141 1674.909883311 -0.982097812754963 0.327612285343547 EIF3E other 1 1 1 3.36294669026819 -0.982097812754963 1.55789727490705e-08 123.249673951077 24.5302269935089 5.02440005890247 1.40113680617446e-06 -232.537722575798 111.754357521989 -2.08079333756667 0.0391304631873094 EMC2 other 0.000164186793802454 1 0.0151729104740632 5.02440005890247 -2.08079333756667 1.60630676818263e-08 688.168677372263 122.852745460317 5.60157345115703 9.69888920693714e-08 -689.442653430657 494.952177021484 -1.39294801687625 0.165669439746702 ESRP1 other 0.000169176228824994 1 0.00112788382587472 5.60157345115703 -1.39294801687625 0.600158481151007 14.430094929621 14.316533130807 1.00793221360063 0.315078387213021 10.5247747359715 88.2987218028491 0.119195097291113 0.905277151387662 WISP1 other 1 1 1 1.00793221360063 0.119195097291113 0.0191021987028453 1621.52158596392 605.477276295979 2.67808826102215 0.00821337936770225 -1487.79186237943 3729.31347503726 -0.398945240816627 0.690489811908951 NDRG1 other 1 1 1 2.67808826102215 -0.398945240816627 0.000248031718973638 76.8390407393268 21.8499054695466 3.51667611772608 0.000577357596886346 -43.7260866547345 70.5711912780469 -0.619602501571158 0.536453323616877 ZC2HC1A other 1 1 1 3.51667611772608 -0.619602501571158 0.0794525637621902 10.2584966558749 6.00168174683176 1.70927034931339 0.0894552162610371 -12.6593652855521 19.3843324007029 -0.653072028680909 0.514702964626858 IL7 other 1 1 1 1.70927034931339 -0.653072028680909 1.18114259857753e-05 148.948416993973 37.3511453836002 3.98778713381495 0.000105067391104577 -160.429901988037 135.887455018756 -1.1806086291475 0.239678047215156 ARMC1 other 0.0968773159353289 1 0.959055146002576 3.98778713381495 -1.1806086291475 0.0445462932126135 137.469764236509 98.0230368057623 1.40242302948553 0.162941117927423 -888.791469342774 531.353051707446 -1.67269476760647 0.0965586494500497 TRPS1 other 1 1 1 1.40242302948553 -1.67269476760647 0.00229901327811641 79.4219132444928 26.3316212711585 3.01621812142213 0.00300717611644493 -90.6280935545283 113.644443579127 -0.797470520337644 0.426438394818803 SPAG1 other 1 1 1 3.01621812142213 -0.797470520337644 8.68105981709543e-08 381.416724676483 66.6532040924577 5.72240644496854 5.87235577093219e-08 -156.84197233378 320.104008878583 -0.489971909078062 0.624899434503098 CHRAC1 other 0.000868453224102227 1 0.000690882656450173 5.72240644496854 -0.489971909078062 0.0166426325283383 179.899821109123 64.930542804838 2.77065019539185 0.00629766348459321 17.5311781242012 286.935491920808 0.0610979771336188 0.951361973207089 NCALD other 1 1 1 2.77065019539185 0.0610979771336188 3.77778618904668e-05 43.917677595876 9.99956412685989 4.39195919329209 2.08711663481503e-05 13.7436513041666 31.1153540205233 0.441699981787174 0.659329963517606 SNX16 other 0.291923768213528 1 0.205518375030236 4.39195919329209 0.441699981787174 1.09699501141073e-07 516.769659348435 92.1704108863615 5.60667631161555 9.38204036651773e-08 -114.971112245721 405.530419111562 -0.283507985658881 0.777170722784916 UBR5 other 0.00108778025331488 1 0.00109160039664434 5.60667631161555 -0.283507985658881 0.00108919849298576 255.067238267148 75.0743516097872 3.39752835419622 0.000939683587803593 -200.148014440433 312.790547948028 -0.639878716775317 0.5235466908152 GSDMD other 1 1 1 3.39752835419622 -0.639878716775317 0.0430481323212708 524.962774294671 206.406003880933 2.54335031163871 0.0123435302189568 617.961468129571 868.513240085207 0.711516462396065 0.478243585342357 TSTA3 other 1 1 1 2.54335031163871 0.711516462396065 0.00164412288428929 189.453481862965 52.0440809143412 3.64025031347531 0.000413751054807979 116.753228093745 218.990593743803 0.533142661964445 0.594991175782807 PYCR3 other 1 1 1 3.64025031347531 0.533142661964445 0.00132751321299852 2100.09163681147 599.597789540862 3.50250063199799 0.000663209001285141 -598.479082698913 2522.98193439405 -0.237211005968876 0.812926451708269 EEF1D other 1 1 1 3.50250063199799 -0.237211005968876 0.664310431221719 3.47880530163549 4.08916321632754 0.850737698056422 0.396253251377112 12.2173907425951 24.5786521732877 0.497073259203084 0.61985560736468 ANXA13 other 1 1 1 0.850737698056422 0.497073259203084 6.98432720302216e-10 323.780735123256 46.4563388335615 6.96957063885857 9.5767168982945e-11 64.0918099164301 431.502218927699 0.148531820011728 0.88212390481813 SQLE other 7.9439737607174e-06 1 1.24851658203065e-06 6.96957063885857 0.148531820011728 2.11294225903609e-06 41.8367880160247 52.7990642387425 0.792377452502767 0.429375572131599 -315.257446437904 100.481410528766 -3.13747035176872 0.00204696159220674 SH2D4A other 0.0187016519347284 1 1 0.792377452502767 -3.13747035176872 2.82082490937431e-16 165.664384387603 51.4750462694928 3.2183435740938 0.00157618304998079 -393.746664344192 97.9616841844866 -4.01939459924625 9.15542541773402e-05 INTS10 essential 3.85804222855124e-12 1 1 3.2183435740938 -4.01939459924625 3.31440786350396e-12 87.3451124418403 20.4182466988713 4.27779690048847 3.35934537266975e-05 -63.5361020161988 39.4820900161738 -1.60923856842865 0.109680885638577 ERI1 other 4.1393639807301e-08 1 0.323538552841824 4.27779690048847 -1.60923856842865 1.30314570883065e-05 522.760035767892 192.771656347244 2.71180963878959 0.00746800754103631 -290.898818382144 346.603299721981 -0.839284619088973 0.402636378650738 SLC39A14 other 0.106424434453234 1 1 2.71180963878959 -0.839284619088973 4.06208284954539e-17 73.0252154484518 12.0303681854169 6.07007319501428 9.77621821691124e-09 -26.6376090112536 23.065801772241 -1.15485294091581 0.249962964776153 MTMR9 other 5.61014262350714e-13 1 0.000119064561663762 6.07007319501428 -1.15485294091581 1.20219168034682e-15 152.865771207944 54.4710159206581 2.80636901339617 0.00566671061073612 -437.872563783795 104.051461509204 -4.20823078727309 4.38551211674121e-05 LEPROTL1 other 1.63029213771832e-11 0.631469889689567 1 2.80636901339617 -4.20823078727309 1.12699656609929e-18 114.433544912015 33.8639896950132 3.37921036306205 0.000923725817005832 -292.402416327483 64.6875693567235 -4.52022574406858 1.23480532820518e-05 DCTN6 essential 1.57937298773154e-14 0.179170253122572 1 3.37921036306205 -4.52022574406858 1.04161229411385e-16 186.068338333408 31.7696467273473 5.85679595150299 2.75918978022585e-08 -53.9250675383216 58.1752640631172 -0.926941517271251 0.355407327892497 R3HCC1 other 1.43242522686536e-12 1 0.000329419667861164 5.85679595150299 -0.926941517271251 2.71912867553404e-13 165.300906586188 94.7099305345058 1.74533869524869 0.0829467331703556 -816.957618722777 179.972401336463 -4.5393494372254 1.14020040799347e-05 GSR other 3.50903555577668e-09 0.165500089220252 1 1.74533869524869 -4.5393494372254 1.43267286440448e-06 24.579125061568 15.3564951448783 1.60056867336461 0.111521920953116 -65.3807191152109 28.1201792328482 -2.32504631545297 0.0213750570774692 TNFRSF10A other 0.0128883250881827 1 1 1.60056867336461 -2.32504631545297 2.67083350900409e-06 51.3074968723861 17.9928668179379 2.85154652627314 0.00495612082253812 -37.9483913579028 34.1909177831322 -1.10989683279646 0.268796290346577 UBXN8 other 0.0233724640372948 1 1 2.85154652627314 -1.10989683279646 1.33816483402949e-23 445.706804578973 91.2131037410993 4.88643392559115 2.58039394163267e-06 -779.505615242025 173.327561544951 -4.49729753475974 1.35822216592488e-05 PPP2CB other 1.91959745441531e-19 0.197010125167405 0.0274579719329132 4.88643392559115 -4.49729753475974 4.44267939088254e-08 53.514314671564 21.5404356460969 2.48436547666856 0.0142799911002707 -94.1286587954019 40.2942565775479 -2.33603165290437 0.0210561861530915 ERICH1 other 0.000453686419396925 1 1 2.48436547666856 -2.33603165290437 6.35669080193117e-17 698.992569305516 121.397001872333 5.75790636115225 4.56456235570655e-08 -394.811462261107 242.087669417578 -1.63086151067072 0.104989874527106 TUSC3 other 8.7652409467829e-13 1 0.000539485624820957 5.75790636115225 -1.63086151067072 1.69966693975362e-10 167.504107542942 51.0496475214321 3.28120008022815 0.00132487672502248 -225.966392830471 95.1761217636298 -2.37419206249714 0.0190389367392318 ARHGEF10 other 1.99115981992137e-06 1 1 3.28120008022815 -2.37419206249714 1.70261413681797e-12 19.1488497970234 28.1006737329767 0.681437391109662 0.496611638370485 -259.393311424705 51.7437360500037 -5.01303792934538 1.44808076115065e-06 KCTD9 other 2.14614511945905e-08 0.0211188098206211 1 0.681437391109662 -5.01303792934538 9.42532589424308e-11 870.86344711855 218.732340767046 3.9814114550442 0.000105855723265325 -625.250833740467 414.548738466618 -1.50826857187702 0.133561518354005 ASAH1 other 1.11718387824463e-06 1 0.965510051903028 3.9814114550442 -1.50826857187702 1.78146522120511e-17 660.58451344141 114.758048200002 5.75632405572229 4.47017737489489e-08 -422.752175229965 232.943170999335 -1.81482965744967 0.0714834536928771 BNIP3L other 2.47053596876725e-13 1 0.000528777281676317 5.75632405572229 -1.81482965744967 2.03058447649003e-05 370.994238749974 109.099962823279 3.40049830586025 0.000863483198354979 -744.003463561863 459.035955344626 -1.62079561502605 0.107175854400013 MAN2B1 other 0.162385840584908 1 1 3.40049830586025 -1.62079561502605 0.0115528544225163 -39.9605024227452 33.7109498125335 -1.18538642918593 0.237667229782825 -289.509545929854 95.9972349524273 -3.01581129991217 0.00299303908592138 KCNN4 other 1 1 1 -1.18538642918593 -3.01581129991217 2.18248624414977e-10 1667.92123558484 371.952220304136 4.48423519080227 1.40564718326643e-05 -1160.79341845141 656.414016335039 -1.76838609408811 0.0789384661285501 NUCB1 other 2.54477896067864e-06 1 0.14055066185481 4.48423519080227 -1.76838609408811 0.357314365200291 -4.62624382207578 5.41778106916535 -0.853900104676708 0.394461325427138 -13.761392092257 9.56119425319432 -1.43929636066744 0.152057360516713 DHDH other 1 1 1 -0.853900104676708 -1.43929636066744 9.67417874641408e-12 515.242685337724 110.267681282792 4.67265366736366 6.35313786032196e-06 -410.726762767715 194.598251043118 -2.11063953846486 0.0363878860508623 GYS1 other 1.19021421117132e-07 1 0.0656215609592655 4.67265366736366 -2.11063953846486 9.04196208635747e-26 141.431443415406 11.6662449716771 12.1231333439996 3.57288930471365e-24 33.7668778527148 44.9272464291957 0.751590193846636 0.453444621405874 MAP4K1 other 1.30403177209447e-21 1 5.1556792667018e-20 12.1231333439996 0.751590193846636 6.40750471156999e-19 944.153148860312 111.639629915429 8.45715047224307 1.90566842689961e-14 -664.700158461428 394.004928147083 -1.68703513833536 0.0936080848512993 ECH1 other 8.99613661504426e-15 1 2.64335267495246e-10 8.45715047224307 -1.68703513833536 1.99002274520593e-08 507.07018977572 109.029724844954 4.65075180641611 7.06922190990821e-06 -628.885983231938 385.129364954864 -1.63292140370974 0.104528474675548 HNRNPL essential 0.000208355381423061 1 0.0726786704557663 4.65075180641611 -1.63292140370974 7.04158422614838e-20 155.797159591925 17.7544894457663 8.77508531393313 3.02897163923609e-15 -104.686474775611 61.7955346707296 -1.69407830733112 0.0922718762649786 NFKBIB other 9.94130861047628e-16 1 4.23207917434066e-11 8.77508531393313 -1.69407830733112 0.00629450226123252 404.208485135965 129.055111696869 3.13206102277754 0.00207564552607009 326.45663161587 239.305678589205 1.36418255321166 0.174487651517204 TUBB4A other 1 1 1 3.13206102277754 1.36418255321166 4.03766749568294e-16 245.70253839968 30.6209499445441 8.02400117712409 2.4281303909715e-13 -101.391706804188 113.843331133908 -0.890624912274626 0.374519721545937 SARS2 other 5.51027720130776e-12 1 3.32435331827908e-09 8.02400117712409 -0.890624912274626 6.59844829087969e-07 445.701892887458 189.7434599171 2.34897104270254 0.0200707777952368 -885.917766112618 333.572725733875 -2.65584593033965 0.00872726878424381 SNRNP70 essential 0.00611478203115821 1 1 2.34897104270254 -2.65584593033965 6.2371939289823e-25 847.852367329053 86.7131921798522 9.77766296010091 6.26105391468174e-18 -1635.45530168303 365.032583756873 -4.48029949779034 1.42881461888296e-05 CLPTM1 other 8.98280669652031e-21 0.20716383159184 8.89257487502248e-14 9.77766296010091 -4.48029949779034 7.56413264663325e-05 5.35140080929924 20.4885263746902 0.261190127168439 0.794288199660775 -357.584249916235 86.2496182173967 -4.14592269863648 5.52224717520525e-05 RELB other 0.563981730132975 0.794430478625027 1 0.261190127168439 -4.14592269863648 3.20171149265477e-22 186.443112792466 19.0428540547109 9.79071268712176 5.77898921457246e-18 -230.621550616879 80.4084096626118 -2.8681272466966 0.00469714014727697 CLASRP essential 4.56980281346615e-18 1 8.2102099771431e-14 9.79071268712176 -2.8681272466966 0.0204615832746939 7.20786327040188 3.90383799054349 1.84635307301736 0.0667238101402929 -4.16883946303641 6.86302378958409 -0.607434797088042 0.544439960362708 LIN7B other 1 1 1 1.84635307301736 -0.607434797088042 1.38813458389673e-26 196.531244159883 18.3692863224223 10.6989047211915 2.08227190354004e-20 -308.589979140314 77.5642713838765 -3.97850677424737 0.000105651954440062 PPP1R37 other 2.005576846814e-22 1 2.98452031934395e-16 10.6989047211915 -3.97850677424737 2.74176183796637e-05 718.762392530201 202.987511291007 3.54091928098852 0.00052505658554047 -147.352099946394 358.12596233993 -0.411453274662418 0.681301325626207 FCGRT other 0.216297591397167 1 1 3.54091928098852 -0.411453274662418 1.17730616635219e-06 207.652194690192 52.7508917770596 3.93646794764703 0.000123970068655416 -63.4589526655006 93.0671239910211 -0.681862186604401 0.49633075918305 PIH1D1 other 0.0106781669288144 1 1 3.93646794764703 -0.681862186604401 2.87574308430516e-17 260.841532212569 33.2537248891053 7.84397937621801 6.97825257203494e-13 -202.030327614893 115.988331202778 -1.74181596993314 0.0835503596909086 ARHGEF18 other 3.97974085436992e-13 1 9.49949522631116e-09 7.84397937621801 -1.74181596993314 1.12582585532191e-10 203.770578260016 41.6323796839175 4.89452151923787 2.42430461646495e-06 -416.440660277244 133.541898596713 -3.11842698548763 0.00216341205248448 PPP1R13L other 1.33061357840496e-06 1 0.0258503601253658 4.89452151923787 -3.11842698548763 1.72562966252926e-05 4.07641172766078 3.74325081295847 1.08900309686676 0.277864845608124 -39.2164415832809 11.1813721702508 -3.50730133888399 0.00059444016934235 PEX11G other 0.138982213020107 1 1 1.08900309686676 -3.50730133888399 1.15628393860879e-11 111.000700968567 19.6270291073432 5.65550192856429 7.1640381029342e-08 -167.879681381474 62.9565436976464 -2.66659621893681 0.00846489627982781 ERCC2 ts 1.41899164946071e-07 1 0.00083833573880536 5.65550192856429 -2.66659621893681 0.00616056519595232 241.862548748041 83.2121839721479 2.90657614309217 0.0042451369521246 3.38217552939442 124.352709446164 0.0271982455746866 0.978340071857145 DOT1L other 1 1 1 2.90657614309217 0.0271982455746866 0.103315822957437 23.9209637272542 13.4126166676311 1.78346733676384 0.0764421501219879 2.57333086777833 23.6635555608428 0.108746585489314 0.913542352733366 SLC17A7 other 1 1 1 1.78346733676384 0.108746585489314 1.09949138663249e-09 210.33772540112 35.3511010905907 5.94996248807382 1.85931281023648e-08 -166.636749518907 176.975065196562 -0.941583207407366 0.347940438204062 RNASEH2A other 1.2385770470415e-05 1 0.000223731110455756 5.94996248807382 -0.941583207407366 2.70865980025202e-06 31.4637585583088 11.3966018291131 2.76080177495832 0.00645309207116173 -113.16778239124 36.5562539870489 -3.09571605535219 0.00232567055377742 KLC3 other 0.0236845212934037 1 1 2.76080177495832 -3.09571605535219 0.00612945881599254 175.611550992732 54.1684194004151 3.24195449925546 0.00144988053593921 192.640197967404 94.9971046216334 2.02785336179114 0.0442662082103526 CD37 other 1 1 1 3.24195449925546 2.02785336179114 8.54844697163712e-06 667.161556474833 170.165932500744 3.92065289844028 0.000137306063350416 -263.83514505959 254.296831927681 -1.03750858026663 0.301274872923874 SF3A2 essential 0.0711059819100776 1 1 3.92065289844028 -1.03750858026663 0.0113490202488353 7.92358532692738 3.35831274976422 2.3593947072034 0.0195349437640886 -0.817095155008319 5.88959381080025 -0.138735400310619 0.889837036150557 DKKL1 other 1 1 1 2.3593947072034 -0.138735400310619 0.981484896218219 0.44726810673443 2.69555492811606 0.165928025457462 0.868440044939758 -0.546886912325322 16.2036230968514 -0.033750903057699 0.973121263116977 LYL1 other 1 1 1 0.165928025457462 -0.033750903057699 0.0550676218559591 119.683438422568 780.143806381201 0.153412021531947 0.878292705183758 -2440.58266209862 1165.85085801398 -2.09339183080084 0.0381049734485592 OAZ1 other 1 1 1 0.153412021531947 -2.09339183080084 2.24828317155338e-14 427.785605373026 52.4400039629667 8.15761962327709 1.35143729671913e-13 -95.8194772190957 315.229361698512 -0.303967487999225 0.761579599018852 TRMT1 other 2.98099865716262e-10 1 1.85552340839536e-09 8.15761962327709 -0.303967487999225 6.7646270053759e-25 218.077988745689 19.4718718005269 11.1996417694055 1.79664530399901e-21 -230.289203122164 117.050062068837 -1.9674419564744 0.0510017805685389 STX10 other 9.74038642504076e-21 1 2.58088097919457e-17 11.1996417694055 -1.9674419564744 2.24129366659194e-15 254.926131689234 31.4476782617867 8.10635779109341 1.3871888947118e-13 -77.8039992644154 100.721653982581 -0.77246546485298 0.441000091194844 DMPK other 3.02462580306583e-11 1 1.90405547688141e-09 8.10635779109341 -0.77246546485298 0.894834321470096 1.78908280319251 3.88425222397824 0.460599029112515 0.645744600424818 1.62778282673803 11.0817800127842 0.14688820973347 0.883414903299125 CLEC4M other 1 1 1 0.460599029112515 0.14688820973347 0.250995430677385 26.3968987097577 317.157565785131 0.0832296043274628 0.933774996969306 -712.958667323935 551.493482620166 -1.29277804687127 0.197987073777873 IL4I1 other 1 1 1 0.0832296043274628 -1.29277804687127 0.0473379278464016 10.2236843070917 11.1599476747683 0.916105039650548 0.36109211828723 -26.2810162998407 16.7008670191464 -1.57363185214943 0.117693580573767 TLE6 other 1 1 1 0.916105039650548 -1.57363185214943 4.0459451525815e-33 270.774438871298 18.2074012626163 14.8716686673597 2.58739272129714e-31 -137.51197691036 127.554323584354 -1.07806598040889 0.282734939016274 CCDC130 essential 5.87875830670093e-29 1 3.75870540622835e-27 14.8716686673597 -1.07806598040889 1.1896434421725e-11 1156.16325174675 222.515033183403 5.19588827418152 6.24914327783579e-07 -576.083282609628 386.923106443547 -1.48888312177779 0.138524125136351 PTOV1 other 1.45885975313613e-07 1 0.0069181650242 5.19588827418152 -1.48888312177779 7.81272524137177e-05 585.382587572202 570.328104887938 1.02639617889289 0.306368278219492 -2822.21525183658 853.49628103995 -3.30665207866849 0.00118330229181974 AES other 0.581344885210473 1 1 1.02639617889289 -3.30665207866849 0.502229437554439 14.6061991233563 27.6257732661032 0.528716390403382 0.597748850002957 -36.8092673763307 59.2454676840778 -0.621300984112631 0.535302645576463 NOVA2 other 1 1 1 0.528716390403382 -0.621300984112631 4.3141628143125e-06 398.052171605777 103.035099764166 3.86326768758284 0.00016815433414704 -195.214474055157 151.727283978221 -1.28661417338215 0.200279172892582 SGTA other 0.0369464903417723 1 1 3.86326768758284 -1.28661417338215 0.00950181718703107 39.9211705193948 13.4019808505513 2.97875149685448 0.00335430068919555 71.3222007431501 30.4783022713223 2.34009755885447 0.0205370853278025 LILRB1 other 1 1 1 2.97875149685448 2.34009755885447 0.0102969223215456 4.8802625334244 1.8079421404317 2.69934663520764 0.00770890135209201 11.1020917014898 4.1115569153251 2.70021598390349 0.00768969333600002 LILRA1 other 1 1 1 2.69934663520764 2.70021598390349 1.68597203559692e-16 119.622657062278 19.8486421073152 6.0267426061449 1.20054655439508e-08 -172.959108483382 55.1975120315302 -3.13345841357095 0.00207103338138499 SNAPC2 essential 2.31264784122829e-12 1 0.000145686324375843 6.0267426061449 -3.13345841357095 1.44196958479318e-09 498.432098168304 85.9994142038024 5.79576155003933 3.87308481982893e-08 -1031.15003303276 608.663419857076 -1.69412190611831 0.0923174605412358 C19orf53 essential 1.61370816234205e-05 1 0.000459502783024505 5.79576155003933 -1.69412190611831 8.26973662110137e-23 230.306873571186 25.8119164737409 8.92250189192588 1.3126789008868e-15 -145.435537615776 71.7809088608169 -2.0261033180532 0.0444917484053473 TIMM44 essential 1.18331661311339e-18 1 1.83906314014241e-11 8.92250189192588 -2.0261033180532 1.52924915293351e-13 74.5480275516593 13.1435318821952 5.67184134522057 6.61931775393041e-08 -67.8515967438952 28.1872541948608 -2.40717298232852 0.0172370617633995 CCDC61 other 1.98618879983004e-09 1 0.000776445972536037 5.67184134522057 -2.40717298232852 0.0111723310172916 51.19448960178 20.9370398673193 2.44516368723592 0.0156364795244369 -159.434288102233 154.261553686031 -1.03353223335692 0.303018338525999 IL27RA other 1 1 1 2.44516368723592 -1.03353223335692 1.38558386588173e-06 218.729178847066 43.8886339536247 4.98373175793506 1.68940958990669e-06 -203.070500708907 310.600500060036 -0.653799657983987 0.514235303022469 ASF1B other 0.0124799538799967 1 0.0181966306928849 4.98373175793506 -0.653799657983987 0.015302307531776 363.954608113433 167.792495742307 2.16907559842479 0.0316211781869122 -142.287350662989 331.635290897763 -0.429047675468452 0.668492043171331 TNNT1 other 1 1 1 2.16907559842479 -0.429047675468452 7.22861145090959e-11 189.566632430351 41.3011763299098 4.58986036901493 9.0310044754686e-06 -141.076364103223 71.479721001417 -1.97365577434789 0.0501759539642936 VRK3 other 8.60783051574313e-07 1 0.0920169046005495 4.58986036901493 -1.97365577434789 3.55693873553979e-21 408.734380670233 39.3789051154848 10.3795262837186 2.33121128816965e-19 -341.143932776624 240.172563137863 -1.42041175861042 0.157563093155879 FAM32A essential 5.05832257581113e-17 1 3.33200029418088e-15 10.3795262837186 -1.42041175861042 2.2072157474921e-10 641.156788914827 123.451633880295 5.19358690332543 6.39805127087891e-07 -298.40853352411 245.823347322067 -1.21391453161342 0.226626753184189 PPP6R1 other 2.57273067527679e-06 1 0.00707688451071916 5.19358690332543 -1.21391453161342 1.18345795747124e-45 410.923079230637 20.3677887777086 20.1751443770062 7.81310390884628e-45 92.0504788346597 118.06716712141 0.77964501968615 0.436812107010169 C19orf44 other 1.72560004778882e-41 1 1.13930681198796e-40 20.1751443770062 0.77964501968615 1.42718904894925e-40 195.999879573207 10.8239609919564 18.1079624842386 6.95929120257208e-40 49.3406873961318 63.4529375496529 0.777595006653899 0.438008517845376 MED26 other 2.07898628760437e-36 1 1.01362076365462e-35 18.1079624842386 0.777595006653899 0.222547248509254 99.4785600581292 58.5689636824829 1.69848591819769 0.0914756689681537 93.0736805791254 194.668906811833 0.478112720225477 0.633261434060473 OLFM2 other 1 1 1 1.69848591819769 0.478112720225477 0.0612569484056855 -9.8838771804046 4.60655769809858 -2.14561019923495 0.0334816447185007 11.8536888489087 28.0673837480326 0.422329667607143 0.6733772964914 RASAL3 other 1 1 1 -2.14561019923495 0.422329667607143 4.68542149402124e-26 156.619128084599 12.370487832176 12.6607075007364 2.11087710795743e-25 -56.3386298294855 79.7651970324839 -0.706305906905011 0.481100891136285 AKAP8 other 6.76200030017145e-22 1 3.05000633328769e-21 12.6607075007364 -0.706305906905011 0.77460096447248 -9.62277337099147 15.2421458247107 -0.631326683372294 0.528794258608623 -48.741446899501 100.505015302603 -0.484965319917114 0.628413175689285 EPHX3 other 1 1 1 -0.631326683372294 -0.484965319917114 6.93772906929506e-20 311.08650658864 30.5232115020054 10.1918012974552 7.30842508824222e-19 -313.541808832256 214.981535603472 -1.45845924838203 0.146804709005265 ILVBL other 9.7953796729377e-16 1 1.04247375458687e-14 10.1918012974552 -1.45845924838203 3.55816973903199e-07 49.5485236938031 12.0750495674132 4.10338056313403 6.58003993143155e-05 -24.8156956257593 24.372794870048 -1.01817193137155 0.310193151437341 ZNF419 other 0.00337350072957623 1 0.613851925203249 4.10338056313403 -1.01817193137155 0.464140630701003 28.3509595188845 23.6174576821935 1.20042385172812 0.231867118417849 -3.40671610045585 163.160356443651 -0.0208795578454892 0.98336948204855 SYDE1 other 1 1 1 1.20042385172812 -0.0208795578454892 0.394562356445932 -1.31090396272943 2.22490317777078 -0.589195959548622 0.556598789051194 16.5010455029714 15.7221577544106 1.04954076665096 0.295584298499026 CASP14 other 1 1 1 -0.589195959548622 1.04954076665096 0.0510307334306399 0.261183296360404 1.77360617759037 0.14726115620281 0.883121040511076 30.7314619341314 12.7071272998599 2.41844291073327 0.016769354469854 SLC1A6 other 1 1 1 0.14726115620281 2.41844291073327 0.0114782819029583 5.14406689439312 2.58875936872224 1.98707804075747 0.0486759206716385 -4.19533576471374 5.15184571843755 -0.81433645221544 0.416701577642225 AURKC other 1 1 1 1.98707804075747 -0.81433645221544 2.38803366587698e-06 212.713623898816 39.7029305773569 5.35763030097657 3.82839188287091e-07 257.633141188554 178.065385912753 1.44684571831826 0.150403861628542 POP4 essential 0.0210218603607151 1 0.00429392433582801 5.35763030097657 1.44684571831826 8.0943813757844e-05 254.503917661383 57.2310633318004 4.44695420362683 1.85919844327059e-05 168.017941022867 265.680286961257 0.63240650235886 0.528240602546743 CCNE1 og 0.600926873338234 1 0.183930501992759 4.44695420362683 0.63240650235886 1.10734466641471e-11 556.058453750555 74.3397438228107 7.47996193094132 9.84428999205893e-12 -1.04955430060073 341.53787856296 -0.00307302459398292 0.997552795654045 URI1 essential 1.35992998482391e-07 1 1.31224385594146e-07 7.47996193094132 -0.00307302459398292 3.51340365607191e-16 419.121851928905 46.3976622952933 9.03325364242374 8.02609991166883e-16 12.6726249716516 225.465689615327 0.056206445394298 0.955252646681902 PDCD5 other 4.79930939419423e-12 1 1.12654338360184e-11 9.03325364242374 0.056206445394298 1.13400061553546e-34 362.068983452068 23.9531657021238 15.1157048698563 7.00120461644853e-32 -179.291314069584 116.398472602517 -1.54032359755988 0.125602546124116 ANKRD27 other 1.648723494927e-30 1 1.01720501872381e-27 15.1157048698563 -1.54032359755988 3.85279709792622e-08 5458.80144716554 998.656329564604 5.46614614613766 1.8007980141911e-07 -102.082774217458 3658.91028719922 -0.0278997751255605 0.977777977065641 RPS16 essential 0.000395258454276251 1 0.00206227388585164 5.46614614613766 -0.0278997751255605 4.59386191589709e-27 583.055286549771 53.0166164266947 10.9975952040612 3.70183377956444e-21 -349.724814836856 194.73672268415 -1.79588528561244 0.0744606165475828 TIMM50 other 6.64088678562084e-23 1 5.31472275732066e-17 10.9975952040612 -1.79588528561244 2.24578410348081e-23 1488.01390027491 146.216452966394 10.1767883852094 5.34621035247016e-19 -552.935002551567 521.105254787904 -1.06108122585833 0.290282539916444 FBL essential 3.21955609075009e-19 1 7.63064603608066e-15 10.1767883852094 -1.06108122585833 1.31169287920102e-32 658.968762054815 49.3026551368029 13.3657864921542 1.21570071491042e-27 -133.866039932517 171.824001495367 -0.779088129524946 0.437108049924618 DYRK1B other 1.90497156846364e-28 1 1.76130719576221e-23 13.3657864921542 -0.779088129524946 0.00769780593770412 11.4582835384326 6.48723636862488 1.76628118467363 0.079317228739608 -35.4443588993586 23.2987197751177 -1.52130070842828 0.130221803182268 CNTD2 other 1 1 1 1.76628118467363 -1.52130070842828 9.03835561996364e-16 2692.95160386671 322.463580824537 8.35118061078667 3.6572839203256e-14 -1434.57176165085 1427.0392280496 -1.00527843485532 0.316339730481761 GPI other 1.22731830963486e-11 1 5.05070909396966e-10 8.35118061078667 -1.00527843485532 5.6601554344532e-24 1076.00525301381 111.150860122165 9.68058413431244 1.25180838173287e-17 -974.742998767314 399.19506483137 -2.44177116563069 0.0157403524754142 AKT2 og 8.12741718833135e-20 1 1.7750642852972e-13 9.68058413431244 -2.44177116563069 6.94119813201733e-09 1168.63487662704 285.952800216741 4.08681039577602 6.99818173632041e-05 -2695.87273676953 1026.99112265772 -2.62502048683046 0.00953203451869307 PLD3 other 7.47358802874306e-05 1 0.651040846929888 4.08681039577602 -2.62502048683046 4.771525994151e-07 17.7447407433825 4.24019007764525 4.18489275679755 4.77903746521639e-05 -19.3993185855454 14.2498889237276 -1.36136630182734 0.175386484328112 PRX other 0.0044742599247154 1 0.453291703575774 4.18489275679755 -1.36136630182734 1.19470040517303e-06 118.760495156082 32.0479537914078 3.70571225636009 0.00029526484979173 -66.5792545220456 47.9206958671396 -1.38936326606435 0.166767656023949 PIAS4 other 0.0108287644724883 1 1 3.70571225636009 -1.38936326606435 9.90978498048173e-12 225.221116591643 41.2685662560182 5.4574495075607 1.89109017011226e-07 -314.168074080242 138.719650078421 -2.26476979939494 0.0249218970564114 NUMBL other 1.21860625904984e-07 1 0.00216265071854038 5.4574495075607 -2.26476979939494 0.714489091727836 7.89367071340879 9.66498551115389 0.816728664962724 0.415345137297362 8.16032373937151 14.2706743873765 0.571824674704226 0.568274467829227 EBI3 other 1 1 1 0.816728664962724 0.571824674704226 2.55451821012705e-09 116.752307854222 27.1498952714939 4.30028575383884 3.01606838973773e-05 -54.8015470892473 39.9092777115872 -1.37315306694554 0.171700775541127 CCDC94 essential 2.82172081490633e-05 1 0.292226866281689 4.30028575383884 -1.37315306694554 6.04705115045296e-17 557.493757168975 63.8984080353166 8.72468930463571 4.39381448228671e-15 -221.848705454572 280.630056421197 -0.790537935543155 0.43044535054428 TBCB essential 8.34069765181977e-13 1 6.13068934713464e-11 8.72468930463571 -0.790537935543155 0.000303862920320394 74.2211222886223 18.257161885152 4.06531545020611 7.62820807760873e-05 50.9647819316307 27.1761167822088 1.87535188857429 0.0626374503040491 FSD1 other 1 1 0.706448350067345 4.06531545020611 1.87535188857429 1.25466311141205e-06 247.135016819596 50.9158219583967 4.85379607583531 2.97655249119955e-06 -94.4671108323143 223.612926021869 -0.42245818483264 0.673287606988491 POLR2I essential 0.0113446638533877 1 0.0315425267492417 4.85379607583531 -0.42245818483264 1.62635745127975e-09 456.390219264548 73.598872838204 6.20104903328958 5.0518724065991e-09 -65.2086967887615 323.232713805736 -0.201739161921439 0.840390383955374 CLIP3 other 1.81550282286358e-05 1 6.22340161768944e-05 6.20104903328958 -0.201739161921439 0.0387884147977551 45.3468239564429 23.2339614404053 1.95174740531255 0.0528185355213456 -11.98157360948 34.722068618467 -0.345070846473347 0.730521302765942 ZFR2 other 1 1 1 1.95174740531255 -0.345070846473347 6.89879605209944e-07 791.16385550483 208.743928170476 3.79011673507795 0.000214690097350321 -475.234265319868 429.654373302517 -1.1060850182136 0.270392533241736 SLC1A5 other 0.00638000658898156 1 1 3.79011673507795 -1.1060850182136 3.22205946213148e-16 362.608179208711 62.9940435714296 5.75622961554367 4.39017752852646e-08 -361.015375965437 129.367453156258 -2.79061979777387 0.00591339062790344 PRKD2 other 4.40423307878752e-12 1 0.000519489706950536 5.75622961554367 -2.79061979777387 0.000870144030095172 228.44228675136 110.877415708307 2.06031395385639 0.0410962373559255 -267.326678765881 166.477517218644 -1.60578246980213 0.110424917486473 TJP3 other 1 1 1 2.06031395385639 -1.60578246980213 0.00289860689096191 238.770085692708 79.2133384570627 3.01426616203195 0.00301330695163383 -156.942749774168 347.905445439153 -0.451107482885365 0.652546648208658 APLP1 other 1 1 1 3.01426616203195 -0.451107482885365 4.17843815025993e-07 138.437755761764 31.7614481730168 4.35867265899339 2.41693470103661e-05 -35.944716218893 47.2332190093906 -0.761005008186013 0.447848752470864 CACTIN other 0.00394235639477025 1 0.236207028332308 4.35867265899339 -0.761005008186013 1.75467996806758e-06 41.1164209164944 22.0401222578067 1.86552599098813 0.0639736318449362 -127.538549883131 42.4541007388023 -3.00415148745721 0.00310061970175264 CCDC9 other 0.015655254675099 1 1 1.86552599098813 -3.00415148745721 2.69075954282297e-23 1961.47714256494 244.649185177263 8.01750940287717 2.31946332767625e-13 -2394.76229848082 647.969048173433 -3.69579736135768 0.000302352612033664 HNRNPUL1 other 3.85639657677388e-19 1 3.17604113458709e-09 8.01750940287717 -3.69579736135768 7.74469897108838e-06 188.548407811595 65.4175169092709 2.88223119310837 0.00453286350900711 -215.347044965836 97.8973452621651 -2.19972303017151 0.0293671251182997 FZR1 other 0.0646217682147614 1 1 2.88223119310837 -2.19972303017151 0.00549380863082792 178.995085562556 86.8771717488644 2.06032358051407 0.041017980000213 -254.932635532117 230.932569447649 -1.10392672693103 0.271314008486327 TGFB1 other 1 1 1 2.06032358051407 -1.10392672693103 0.00994234389183615 43.2263600619563 20.8082810091108 2.07736333640582 0.0395566285110118 -182.873759084952 103.928761950186 -1.75960682734395 0.080612946517156 DENND3 other 1 1 1 2.07736333640582 -1.75960682734395 0.0041528992649871 -65.2939671726729 124.84620257176 -0.52299521993985 0.601724394640789 -638.313849992291 219.418177655912 -2.90912018690304 0.00415775513307684 PLIN3 other 1 1 1 -0.52299521993985 -2.90912018690304 2.17006488326405e-07 1649.5798358955 382.689504338666 4.31049144853391 2.87477138346675e-05 -444.700562466264 688.103031225421 -0.646270314598544 0.519053925110183 MYH14 other 0.00209910376158132 1 0.278996562765448 4.31049144853391 -0.646270314598544 2.24388008556815e-14 803.158934232748 108.860613741713 7.37786520419915 9.13776985031648e-12 -516.903664655162 435.643288956121 -1.18652961668193 0.237228690022254 MRPL4 essential 2.97538499346337e-10 1 1.21879574263521e-07 7.37786520419915 -1.18652961668193 0.331607385802246 9.0380279822293 6.06156301381127 1.49103918603769 0.137957658537812 9.79675750944897 11.6758408330851 0.839062269647298 0.402710121349164 SIGLEC8 other 1 1 1 1.49103918603769 0.839062269647298 0.153589614992102 48.9080377142929 31.7726058749138 1.53931465070382 0.125753428618772 -18.3949795575189 83.5730888171531 -0.220106493823205 0.826075991336167 CD79A og 1 1 1 1.53931465070382 -0.220106493823205 0.192228256182453 22.4291883536953 12.3427775700127 1.81719132719267 0.0711193117287665 46.2936459886816 49.3938811351179 0.937234429140006 0.350096033549957 ICAM4 other 1 1 1 1.81719132719267 0.937234429140006 2.28500656783955e-06 3273.97397170969 1005.19179713342 3.2570639563975 0.00138125121608275 -5023.59154188302 2644.0067166928 -1.89999197436483 0.0592792491890085 RPS19 essential 0.0201606129480483 1 1 3.2570639563975 -1.89999197436483 6.57659331566202e-06 1237.90380502428 440.611255707741 2.80951471163821 0.00559299790069468 -1243.55384096208 763.528427181298 -1.62869357144027 0.105382864497211 NOP53 other 0.0552499604448766 1 1 2.80951471163821 -1.62869357144027 0.443829650053943 16.8221023141701 25.1862757783328 0.667907493041974 0.505173300574072 61.9226228366818 48.5140460465329 1.27638545705481 0.203704141094452 NKG7 other 1 1 1 0.667907493041974 1.27638545705481 0.000324272136902217 73.3666186012977 20.0905563573731 3.65179626169849 0.000355639386794569 -12.1914203316509 80.3992899511885 -0.151635920404925 0.879671284543263 ICAM5 other 1 1 1 3.65179626169849 -0.151635920404925 0.00931427146706096 25.4870615343812 48.2282681909384 0.528467276359095 0.59792129141816 -207.04279391287 92.8977529013065 -2.22871692206409 0.0272529657812417 ETFB other 1 1 1 0.528467276359095 -2.22871692206409 0.00254958201309325 30.6498408593594 9.23229815261336 3.31984954912699 0.00111987567418809 50.5873980505271 17.7833412781305 2.84465091567118 0.00503892154594527 CD33 other 1 1 1 3.31984954912699 2.84465091567118 0.440681109809217 -17.8077511473737 18.1178616064892 -0.982883716309854 0.327176900996566 -58.1027768763616 47.9466197326231 -1.21182217224853 0.227401106721843 CEACAM5 other 1 1 1 -0.982883716309854 -1.21182217224853 2.80928096238444e-43 826.149829814995 42.3094614677819 19.5263612713222 1.26463185101193e-43 350.264115177063 426.277558909884 0.821680869320897 0.412520652157307 BABAM1 other 4.09396514648284e-39 1 1.84383323877539e-39 19.5263612713222 0.821680869320897 2.39566086074954e-22 540.978441817712 53.5495286867397 10.1023940842204 9.45815428837686e-19 -269.555054680608 215.896404927978 -1.24853887571926 0.213716320079677 TYK2 other 3.42028501089212e-18 1 1.34816531226524e-14 10.1023940842204 -1.24853887571926 1.09395214082883e-06 269.577162073867 140.969548767071 1.91230776030431 0.0576577363057007 -828.827015566796 271.538213556911 -3.0523402386349 0.00266724241519056 NAPA essential 0.00994730681655654 1 1 1.91230776030431 -3.0523402386349 1.10772406525254e-08 526.055013611511 122.962191740131 4.27818507597261 3.27435042571907e-05 -606.94141961323 323.433658916957 -1.87655614336993 0.0624466440985329 RABAC1 other 0.00011777322261765 1 0.315843842064861 4.27818507597261 -1.87655614336993 0.0387109106872394 83.0723670275926 53.6741260396838 1.54771718064255 0.123716692406933 -135.139978049203 141.181762690711 -0.957205629634024 0.339944545128112 ATP1A3 other 1 1 1 1.54771718064255 -0.957205629634024 0.00294822487600293 113.25585017884 37.043993295821 3.05733372950416 0.00262568640960397 223.372126272254 71.3548411734085 3.13044108288894 0.00208187701287885 MEIS3 other 1 1 1 3.05733372950416 3.13044108288894 2.41608675550864e-14 2630.30116158143 352.092522134494 7.47048288795152 5.5775571129348e-12 981.238187257115 642.324622647008 1.5276359533182 0.128654256971078 PTPRS other 3.19986529899564e-10 1 7.47727306560039e-08 7.47048288795152 1.5276359533182 0.0075541133199483 29.3940613320858 19.8423048565926 1.48138341510864 0.140534460373079 -84.6691717782901 52.5779120297746 -1.61035629810371 0.109354729267996 CNFN other 1 1 1 1.48138341510864 -1.61035629810371 3.80668191908827e-07 269.176336681085 71.2246373325803 3.77925878968225 0.000223921849363407 -311.387387404046 188.730227818307 -1.64990733600886 0.100986924956125 MEGF8 other 0.0036007404272656 1 1 3.77925878968225 -1.64990733600886 1.50410765881533e-10 1190.78560484506 326.804676946357 3.64372265406875 0.0003647065823587 -1601.80890445648 568.625434117548 -2.81698427180334 0.00547076152076033 KDELR1 other 1.76702567757625e-06 1 1 3.64372265406875 -2.81698427180334 1.01057849950865e-08 278.088986537499 72.8996351296898 3.81468283130325 0.000195642586194826 -231.828058329022 127.147489409916 -1.82330032157868 0.0701599332302332 CYTH2 other 0.000107677139122647 1 1 3.81468283130325 -1.82330032157868 2.6641787329581e-17 244.598118473402 38.5565290905682 6.34388323437641 2.28321093179859e-09 -149.655694629421 67.2481537871176 -2.22542458344915 0.0274776878036452 GRWD1 essential 3.6877562021606e-13 1 2.84830563741874e-05 6.34388323437641 -2.22542458344915 0.00993866995442918 108.353774505229 57.8093880016929 1.87432834442143 0.0627430336001642 -81.9903569641098 100.827919586465 -0.81317116628395 0.417351379612018 GRIN2D other 1 1 1 1.87432834442143 -0.81317116628395 0.510864114565988 75.8753137375207 219.284831132085 0.346012596246649 0.729808584620507 -271.001044719127 390.888038854549 -0.693295823308545 0.489175043319906 CLEC11A other 1 1 1 0.346012596246649 -0.693295823308545 0.378942407443426 -60.9443886432214 44.0919625594781 -1.38221084083091 0.168870240818369 -76.2702746413233 76.7180310445596 -0.994163609295756 0.321672982308562 CCDC114 other 1 1 1 -1.38221084083091 -0.994163609295756 2.03514639519062e-07 85.9655049135812 24.384558212687 3.52540752076674 0.000554366281597827 -67.989968547972 42.4280341671173 -1.60247746290036 0.111060093532309 CARD8 other 0.0019751095765325 1 1 3.52540752076674 -1.60247746290036 6.21443321559866e-10 243.168523712446 55.0972922739172 4.41343873131784 1.88331618496909e-05 -160.316682343027 95.8668095900604 -1.6722855702465 0.0964597244084459 LIG1 other 7.09128974231964e-06 1 0.186146971722345 4.41343873131784 -1.6722855702465 1.97828537572107e-06 44.4147572727509 12.4684213032626 3.56217970122078 0.000487246966158256 -31.0758587415484 24.1921689733866 -1.2845420671348 0.200844461546883 ZNF175 other 0.0175592609949002 1 1 3.56217970122078 -1.2845420671348 0.0249491042235343 2.74432352603202 9.97800795641845 0.275037215646506 0.783649261087497 -35.1160235102846 17.3612849083494 -2.02266270588052 0.044805273531207 PLA2G4C other 1 1 1 0.275037215646506 -2.02266270588052 0.0455608136775109 10.3712859104215 4.45304194897495 2.32903395684581 0.0211318262274268 18.026481102505 8.64012697798328 2.08636761339735 0.0385620451269765 SIGLEC5 other 1 1 1 2.32903395684581 2.08636761339735 0.496548742123056 3.42374621143433 2.98897148763546 1.14545964242129 0.253761846557115 2.27504662850037 5.79942733139683 0.392288151656589 0.69537735018324 HAS1 other 1 1 1 1.14545964242129 0.392288151656589 6.23928830858544e-12 479.321256038648 92.7207543670842 5.16951419680001 7.28437522276772e-07 -959.975659606093 326.087451803014 -2.9439208847141 0.00375004381642953 RAB3D other 7.72361499719792e-08 1 0.00802301087035636 5.16951419680001 -2.9439208847141 0.00258015519492041 68.3040302672995 59.1819005468594 1.15413715403102 0.250197756183055 -201.062689276655 103.221779637905 -1.94787078833527 0.0532141135750321 DBP other 1 1 1 1.15413715403102 -1.94787078833527 0.000285541541176788 638.635637309551 208.404295795215 3.0644072612452 0.00258114867462898 -825.410442214789 732.932192199553 -1.1261757240294 0.261866050632889 TMEM205 other 1 1 1 3.0644072612452 -1.1261757240294 0.00125048392507414 907.401289035924 397.694310504449 2.28165519362081 0.0238620866044208 -722.706994482731 770.164505548621 -0.938380033455211 0.349499729836366 CAPS other 1 1 1 2.28165519362081 -0.938380033455211 0.00128929322570033 107.992729267396 39.4575080303517 2.73693739564914 0.00694098500683916 -145.96860593389 141.997518433899 -1.02796589365637 0.305598916692662 PLPPR2 other 1 1 1 2.73693739564914 -1.02796589365637 0.54669339586592 17.2169269529959 19.9973729566148 0.860959436539429 0.390573323531667 -0.882898721613708 34.878305792669 -0.025313692897299 0.979836898021709 FAM83E other 1 1 1 0.860959436539429 -0.025313692897299 0.00864036091126673 188.044575743211 65.4350740722102 2.87375812451433 0.00461837732924445 82.9632796099406 113.626367289889 0.730141089508572 0.466392009298644 RASIP1 other 1 1 1 2.87375812451433 0.730141089508572 6.53560139912702e-09 254.742388797365 66.6951402537209 3.81950450704919 0.000192178279187462 -226.659942339374 117.702281352632 -1.92570560004957 0.0559483980153725 BCAT2 other 7.04668542853876e-05 1 1 3.81950450704919 -1.92570560004957 0.0276903115176657 65.0569086540725 28.9401393659908 2.24798187152218 0.0261517096278482 -13.7079191595609 43.1924311950034 -0.317368547690056 0.751440192008526 MIER2 other 1 1 1 2.24798187152218 -0.317368547690056 2.54572695777029e-05 235.468937397035 103.954016417839 2.26512592308678 0.0248726543016725 -362.813060131796 183.456018558503 -1.97765689554685 0.0497179281780414 PLEKHA4 other 0.2015809764716 1 1 2.26512592308678 -1.97765689554685 1.38937537791596e-16 1736.04485760014 269.000177201299 6.45369410407866 1.34515638825778e-09 -1197.03849105226 524.000938416561 -2.28442051014164 0.0237128231033431 PPP2R1A other 1.90691770618965e-12 1 1.69045803312356e-05 6.45369410407866 -2.28442051014164 3.4538468304929e-20 689.103527437131 71.278054334815 9.66782179828028 1.83201582932952e-17 -423.332609475498 347.705139343957 -1.21750460828458 0.225336950724469 TNPO2 other 4.88408480300001e-16 1 2.59596643015993e-13 9.66782179828028 -1.21750460828458 9.19250720621021e-09 503.98877540392 117.851746541697 4.27646420348641 3.38949175768789e-05 -1244.97944812403 489.423347540361 -2.54376799631807 0.0119922851655452 WDR83OS other 9.82403245127686e-05 1 0.326238581677459 4.27646420348641 -2.54376799631807 7.37795911625159e-25 227.727194999127 19.514524323728 11.6696257219157 9.29001411341877e-23 -46.4169138766784 99.2152660663732 -0.467840441466198 0.640582265418985 GCDH other 1.0622785535579e-20 1 1.33831943317911e-18 11.6696257219157 -0.467840441466198 0.619500380497385 7.0107280848382 7.50569501808864 0.934054483687709 0.351719312133226 12.1011262433892 15.9068457984587 0.760749578936741 0.447954998296481 LILRB5 other 1 1 1 0.934054483687709 0.760749578936741 1.43557279564472e-12 305.336541540676 44.2864617477823 6.8945797313773 1.45647077053516e-10 -285.743853036755 218.867629808595 -1.30555556930299 0.193729574387204 DNASE2 other 1.8147075709745e-08 1 1.88860564815294e-06 6.8945797313773 -1.30555556930299 1.88262247316684e-20 105.943019576176 9.79524381529742 10.8157613607047 1.86874227704661e-20 71.8389399177932 48.408965463555 1.48400072651579 0.139935314667869 MAST1 other 2.66541689750961e-16 1 2.67921580260173e-16 10.8157613607047 1.48400072651579 3.90770321028274e-12 66.2991844817184 12.8871870653755 5.14458152468716 7.95040256231978e-07 -56.1067291975464 26.6128172689876 -2.10825966414794 0.0366065208662813 LENG1 other 4.87056128129641e-08 1 0.00873590233547697 5.14458152468716 -2.10825966414794 5.94254941244019e-15 285.740264755861 47.2441880604922 6.04815695826954 1.05470515521932e-08 -211.892432533599 97.7632959162134 -2.16740271026867 0.0317307119948145 PRPF31 essential 7.96242195772861e-11 1 0.00012820995866846 6.04815695826954 -2.16740271026867 1.12293798967747e-05 51.6208572481075 30.5710417310104 1.6885540801099 0.0933157604277182 -184.339658122705 63.2612374539883 -2.91394328567759 0.00409738555555634 TFPT other 0.0923504202710753 1 1 1.6885540801099 -2.91394328567759 0.0656590691583141 55.048100336667 24.2788627552596 2.26732614668048 0.0247990320209966 16.7215615140843 120.015827572744 0.139327969087652 0.889377881724095 JAK3 og 1 1 1 2.26732614668048 0.139327969087652 3.49900816276449e-07 2624.15608631789 499.538000350553 5.25316609442399 5.04095681455355e-07 -1164.27284775795 2466.82532772845 -0.471972147630758 0.637632528031498 RPL18A essential 0.00331985894483095 1 0.00561814636981993 5.25316609442399 -0.471972147630758 0.206359956780539 13.6197536440896 7.65726362058506 1.77867111790112 0.0773192375641912 16.033364780688 37.8132030538164 0.424014986455101 0.672162334162664 SLC5A5 other 1 1 1 1.77867111790112 0.424014986455101 0.0254540080450996 32.1194667493232 11.7357376248571 2.73689373229442 0.00694186225116805 40.8608243805159 42.1956172360262 0.968366552193228 0.334399648536124 KCNN1 other 1 1 1 2.73689373229442 0.968366552193228 0.00317055703990816 86.9186093753576 29.7819010971542 2.91850439942744 0.00404812657384853 -50.3301689212387 104.264256091593 -0.482717383769804 0.629986366723489 ARRDC2 other 1 1 1 2.91850439942744 -0.482717383769804 1.13736131202184e-07 1278.56530064514 248.723847679326 5.14050145402046 8.25596704788289e-07 -396.983397087255 867.884882105932 -0.457414808429397 0.648021778239894 PIK3R2 other 0.00112632890729523 1 0.00906422622187062 5.14050145402046 -0.457414808429397 2.12822170494698e-07 55.9839085496378 11.3909259772746 4.91478117418444 2.26549475496869e-06 -26.3590214266468 39.7469424066251 -0.663171047397427 0.50821893062106 RAB3A other 0.00206160836558214 1 0.0242000149725755 4.91478117418444 -0.663171047397427 6.87615428964134e-11 2565.45812816021 364.107266215412 7.04588555681952 6.88770776076456e-11 1318.00949028939 1194.14403141258 1.10372740274076 0.271539730086222 ISYNA1 other 8.19912637496833e-07 1 9.01394314651258e-07 7.04588555681952 1.10372740274076 5.61210614801975e-09 117.59614021511 22.6460330691874 5.19279203805072 6.68910806250839e-07 -90.8625516629741 73.0918992385339 -1.24312752315337 0.215773408994909 ELL other 6.07117643092776e-05 1 0.00738945767665301 5.19279203805072 -1.24312752315337 7.87573150137481e-14 312.107520020969 47.4521492400986 6.5773105121491 7.49577158913586e-10 -308.809685251737 151.341984839268 -2.04047598278632 0.0430567944067605 CRTC1 og 1.03069698158492e-09 1 9.49789218059405e-06 6.5773105121491 -2.04047598278632 0.103270149555323 886.587870822381 418.23817549392 2.11981574798944 0.0356786927436858 854.815684065589 1334.24173906448 0.640675268235089 0.522717791176521 COMP other 1 1 1 2.11981574798944 0.640675268235089 0.334139938581784 6.39913657353222 4.84872348426285 1.31975696166247 0.188862091450246 24.2974645159917 21.1372918828647 1.14950697802914 0.252117596414864 UPK1A other 1 1 1 1.31975696166247 1.14950697802914 6.05552804238427e-07 741.765236493949 195.770685845036 3.78894947061226 0.000219023497479048 -1387.52939299477 659.665597005388 -2.10338298570304 0.0371125719151651 COPE essential 0.00562982442100465 1 1 3.78894947061226 -2.10338298570304 1.48821989548629e-14 319.344815353172 40.4920990999923 7.88659571746512 6.47261881854764e-13 -51.7898482703196 136.022292667983 -0.380745297366318 0.703941911800736 DDX49 essential 1.97829070706993e-10 1 8.81505956898002e-09 7.88659571746512 -0.380745297366318 3.87798085065879e-08 11.1625428255272 2.02346948837192 5.51653627083281 1.41825418816076e-07 -3.2818366565233 8.82101553751329 -0.372047486206841 0.710365650455163 ETV2 other 0.000397686936235059 1 0.00163510525353055 5.51653627083281 -0.372047486206841 1.5284556699743e-12 231.140287658521 33.0993491026649 6.98322758376877 9.07311818887314e-11 -78.5029044231361 111.569093813003 -0.703625903377079 0.482771277212727 ARMC6 other 1.92998097447654e-08 1 1.18367899892039e-06 6.98322758376877 -0.703625903377079 3.02407034136509e-11 469.941470006171 71.8828585948734 6.53760130290208 8.56106921131191e-10 -270.533304960313 313.362675439415 -0.863323318838007 0.389293629833478 TMEM147 other 3.65337937940317e-07 1 1.08331769799941e-05 6.53760130290208 -0.863323318838007 8.51605857061032e-16 20.000504614933 2.38049719841723 8.4018181698475 2.55217437393923e-14 -5.84266106391177 10.2794469862896 -0.56838281978637 0.570592317033248 GAPDHS other 1.15716203857453e-11 1 3.53323020328147e-10 8.4018181698475 -0.56838281978637 0.0868431056509282 40.1886355968962 19.6989856779721 2.04013730726431 0.0430232368693298 -6.12143824869736 90.5483462690611 -0.0676040866666712 0.946187371543463 MAG other 1 1 1 2.04013730726431 -0.0676040866666712 0.00177808616648386 35.0369227693743 10.1594645470003 3.4486977741085 0.000730206471725433 16.8904377956953 32.8109631349586 0.51478031066084 0.607459238423783 TMEM59L other 1 1 1 3.4486977741085 0.51478031066084 0.60436100885815 -1.80109952968094 3.92135178527695 -0.459305777268778 0.646649912399324 -18.0336002711749 18.018897483822 -1.00081596487055 0.31845580151956 HAMP other 1 1 1 -0.459305777268778 -1.00081596487055 4.57854000255993e-32 1080.68949911914 77.0550141125921 14.0249081979278 1.7338824251959e-29 -221.137671301759 351.250410421692 -0.629572705797761 0.529889281867476 USF2 other 6.64666652171626e-28 1 2.51499645774666e-25 14.0249081979278 -0.629572705797761 1.02233648252805e-30 3228.47741805548 230.335477566378 14.0164140243011 2.08261076336724e-29 528.72311173769 1034.86110301307 0.51091215062415 0.610134856431534 LSR other 1.48238789966567e-26 1 3.02061865118784e-25 14.0164140243011 0.51091215062415 3.05644766898405e-13 444.94838927195 64.4039568972427 6.90871199081558 1.25584868911588e-10 -236.2737345224 207.941693851902 -1.13624992730259 0.257640251273673 KXD1 other 3.93701024241835e-09 1 1.63147303203044e-06 6.90871199081558 -1.13624992730259 8.29350241536634e-14 1945.47119595509 264.338050819197 7.35978490393636 1.07772832217337e-11 -560.472967592962 853.129075862343 -0.656961511980395 0.512199141005503 FKBP8 other 1.08437544080915e-09 1 1.43574967079936e-07 7.35978490393636 -0.656961511980395 1.72665959951013e-11 108.530351756208 20.6811169996009 5.24779932139559 5.16652342670099e-07 -184.716070544196 67.9864277592106 -2.71695508401192 0.00736356930526643 SUGP1 essential 2.10514338372275e-07 1 0.00575292383563155 5.24779932139559 -2.71695508401192 1.63184679654684e-22 1406.72280728148 122.117673854361 11.5194038903751 1.31691935024354e-22 864.109364291326 548.50817806748 1.57538100404589 0.117194339544204 HPN other 2.33207225694509e-18 1 1.89649555628572e-18 11.5194038903751 1.57538100404589 4.84442100685133e-14 66.4152619167484 9.46061956760837 7.02018101902581 6.76427197654095e-11 -47.1986208632521 31.9432753472426 -1.4775761204878 0.141576800644084 ZNF14 other 6.37525804501635e-10 1 8.85849058047803e-07 7.02018101902581 -1.4775761204878 7.40562108439158e-05 21.0168747806028 5.2159286586191 4.02936392657007 8.71597178316569e-05 -8.96070073383149 23.4280545572884 -0.382477371815913 0.702627898606722 SCN1B other 0.552755557738988 1 0.802130883204738 4.02936392657007 -0.382477371815913 4.49632264006069e-06 16.5280015240998 3.65532172205934 4.521627036098 1.22762379297823e-05 -2.51987045151459 11.9359636210922 -0.211115795214195 0.833079692553881 PBX4 other 0.0384165806366785 1 0.123646268428767 4.521627036098 -0.211115795214195 2.69202792673807e-15 595.088337632213 106.81988245755 5.57095106211803 1.11291158657752e-07 -934.366277940307 282.829829731642 -3.30363412807928 0.00118851782281075 ERF other 3.6280460368649e-11 1 0.00128975323768469 5.57095106211803 -3.30363412807928 4.11417417584874e-22 650.698651479218 84.9498475646007 7.65979775283752 1.97714447963994e-12 -809.383685033553 224.923959563174 -3.59847695463597 0.000431669277463783 GSK3A other 5.8696922966834e-18 1 2.67211076423338e-08 7.65979775283752 -3.59847695463597 1.56259405372245e-11 668.542059039507 107.066703703757 6.24416402030364 4.00701578298155e-09 -382.10912028198 346.211310893905 -1.1036875695811 0.271461526612977 ATP13A1 other 1.90792733959511e-07 1 4.95507571723498e-05 6.24416402030364 -1.1036875695811 2.17573993959672e-24 295.744410500698 35.6658559580141 8.29208784022594 5.15848181981513e-14 -351.306527397937 94.1326305381713 -3.73203771518401 0.000266693752118913 ZNF574 essential 3.12784373716424e-20 1 7.11199888497912e-10 8.29208784022594 -3.73203771518401 6.65216973344945e-13 344.707761611349 52.7618776508478 6.53327320707683 8.88461643572755e-10 -116.770766746845 139.254034482003 -0.838544945438804 0.403024387850179 GRIK5 other 8.49016423080153e-09 1 1.12363744062646e-05 6.53327320707683 -0.838544945438804 1.5960992428475e-18 435.261326230662 59.2832650384052 7.34206062956703 1.21471855278935e-11 -810.347536416426 226.823467126551 -3.57259126086946 0.000474741774516011 SIPA1L3 other 2.23437933006221e-14 1 1.6175192248943e-07 7.34206062956703 -3.57259126086946 4.55448683999703e-11 51.4348792017684 8.27274251676197 6.21739152373626 4.48052005406521e-09 -24.7152430163087 27.0806420487944 -0.912653509904838 0.362842145316563 ZNF85 other 5.46538420799643e-07 1 5.52761759070025e-05 6.21739152373626 -0.912653509904838 0.00491653933345495 44.0451259081611 40.631756789406 1.0840074214966 0.280044785128133 -257.089969669182 115.722529110774 -2.22160690441778 0.0277588735260932 ETHE1 other 1 1 1 1.0840074214966 -2.22160690441778 9.26395127760537e-07 102.506429603944 31.3602763996694 3.2686711142962 0.00133276499599999 -209.030092608269 89.1783665124529 -2.3439551629271 0.0203578595705201 CADM4 other 0.00847558902388115 1 1 3.2686711142962 -2.3439551629271 2.1657767234429e-15 105.901395354373 19.7900733008067 5.35123815585142 3.08848618220242e-07 -228.500624852155 56.5084599131309 -4.04365337868744 8.27121766795351e-05 SMG9 other 2.9242317319926e-11 1 0.00348566550523365 5.35123815585142 -4.04365337868744 2.24336900243023e-14 350.740389734852 52.4127119596201 6.69189547003541 3.91763379215872e-10 -209.66700741845 131.632179935867 -1.59282485119219 0.11326335571169 AVL9 other 2.97493163412273e-10 1 5.00516893286198e-06 6.69189547003541 -1.59282485119219 0.678857770009668 -1.49626507473389 2.44432615160448 -0.61213806257063 0.541349158049326 -5.8282594800116 7.34836772348179 -0.793136612010765 0.428918501204765 RUNDC3B other 1 1 1 -0.61213806257063 -0.793136612010765 4.70668723299529e-06 52.8942735474283 11.7134015520744 4.51570564812244 1.25302793495637e-05 -41.2471491583229 36.2898674367187 -1.13660236511606 0.257481614332528 CFAP69 other 0.0400962685378869 1 0.126092201094659 4.51570564812244 -1.13660236511606 0.000345731407807203 278.073678558644 71.6410292800305 3.88148636826126 0.000155509380246801 4.33326373145591 224.601058154677 0.0192931581313909 0.984633053258656 CDK6 og 1 1 1 3.88148636826126 0.0192931581313909 1.26848682201281e-10 303.332015139281 52.9700374923408 5.72648292316465 5.21728743841037e-08 -407.887045206729 166.056894870095 -2.45630899894772 0.0151482754381117 PMPCB essential 1.4950385684243e-06 1 0.000615274707611735 5.72648292316465 -2.45630899894772 1.01674590566804e-08 150.821060054367 27.6737693016306 5.44996449202459 1.95900770525824e-07 -134.019585737387 86.7550867836295 -1.54480377700085 0.124446208368816 DNAJC2 other 0.000108313941330816 1 0.00223777450171648 5.44996449202459 -1.54480377700085 0.842518952265758 10.3193371194493 248.824182042131 0.0414724044695222 0.966973718149743 -429.701438413556 787.637610301042 -0.545557287759938 0.586170005014155 TFPI2 other 1 1 1 0.0414724044695222 -0.545557287759938 0.0001197098442949 43.4920119144327 22.4088336193875 1.94084228805219 0.0541277267232396 -228.472447874357 72.0420670051363 -3.17137552227739 0.00183562630669981 BET1 other 0.869931438491039 1 1 1.94084228805219 -3.17137552227739 0.0376700642271577 266.903659441391 116.18069121591 2.29731512739391 0.0229302266965479 686.583352613146 364.605775229431 1.88308413979759 0.0615504843483125 NAMPT other 1 1 1 2.29731512739391 1.88308413979759 9.21369461188232e-15 120.423593910469 22.5131784665837 5.3490267528956 3.12049726498469e-07 -144.581324634004 52.7758967943539 -2.73953326074928 0.00687440076361674 TWISTNB essential 1.23002823068629e-10 1 0.00352054501435572 5.3490267528956 -2.73953326074928 0.473524475388171 -6.70135039150902 5.56922388502984 -1.20328263504047 0.230713484919801 -3.45522975425903 17.8131538091873 -0.193970691056233 0.846454454563402 PIK3CG other 1 1 1 -1.20328263504047 -0.193970691056233 0.683156047554885 -2.09842577879607 13.0871123522572 -0.160342917697511 0.872825254404076 -36.2789346291712 41.8121722971646 -0.86766442966254 0.38695486804994 PON3 other 1 1 1 -0.160342917697511 -0.86766442966254 0.00735974898875986 203.463360555782 89.0773121365289 2.2841210143828 0.0237582438743882 -407.231486271757 284.594173456336 -1.4309199704478 0.154519419051063 PON2 other 1 1 1 2.2841210143828 -1.4309199704478 0.00013387889963719 1978.14198082101 461.729719254504 4.28419895521316 3.21764118881463e-05 2018.95131752487 1086.37069874405 1.85843682995038 0.0650158042040167 ITGB8 other 0.965132987484505 1 0.31088849166327 4.28419895521316 1.85843682995038 2.7473233876222e-10 324.961779078423 56.4454020277871 5.7570992039077 4.49547482315564e-08 -358.967401621493 180.540529326735 -1.98829261750888 0.0485515463924798 HBP1 other 3.19050403886618e-06 1 0.000531634852586387 5.7570992039077 -1.98829261750888 2.20992070909087e-09 45.1318014343049 7.7824636512264 5.79916636387923 3.66088540538035e-08 -34.9276021448779 25.1582869750173 -1.38831400482719 0.167046417988302 DUS4L other 2.44859214567269e-05 1 0.000434803359597024 5.79916636387923 -1.38831400482719 5.13777144955974e-14 101.589567199139 16.8859022822187 6.01623564445918 1.25129830741514e-08 -70.8747212784965 39.960815366268 -1.7736054839943 0.0781048347966026 SP4 other 6.75873834189583e-10 1 0.000151644841875641 6.01623564445918 -1.7736054839943 3.19533630042684e-08 290.832275705515 46.8967872994577 6.20153943272098 4.8573424424934e-09 285.423505133364 166.409629169743 1.71518623385804 0.0883094618769587 WDR91 other 0.000329630892752032 1 5.98618882612886e-05 6.20153943272098 1.71518623385804 1.00659660041689e-05 94.937440698996 32.344878990626 2.93516141230611 0.0038412263073269 -128.823534113935 76.4715043809215 -1.68459526403765 0.0940791973764431 DNAH11 other 0.0831750770924473 1 1 2.93516141230611 -1.68459526403765 1.2702536224072e-10 169.76675455422 26.7609322934041 6.34382811080401 2.37424192745612e-09 -113.824919321704 86.4111729842901 -1.31724770525216 0.189712154462391 CBLL1 essential 1.49699389400689e-06 1 2.95901771418856e-05 6.34382811080401 -1.31724770525216 0.141248533494321 -30.723421742704 19.3204520027531 -1.59020201692621 0.113853453040983 -99.9347692789397 60.8785811476922 -1.64154235192336 0.102738853665234 DLX5 other 1 1 1 -1.59020201692621 -1.64154235192336 1.85943694885958e-10 864.340670785067 123.379079174021 7.00556914974174 6.81034693949729e-11 16.4879983982789 433.070370618122 0.0380723307732773 0.96967837982643 MTPN other 2.17535528647083e-06 1 8.91610621318985e-07 7.00556914974174 0.0380723307732773 0.138381284937611 3.46391490712811 3.66999120577128 0.943848285434826 0.346716068629203 -8.19876170820764 8.7173439155435 -0.940511443352465 0.348418708495327 STEAP1B other 1 1 1 0.943848285434826 -0.940511443352465 0.288622311358535 213.428518667739 139.67137753084 1.52807627762255 0.128505798667963 -39.2112644372827 498.33526146395 -0.0786845071370076 0.937383766002318 PTN other 1 1 1 1.52807627762255 -0.0786845071370076 1.82080491336741e-08 56.0156281407034 14.4478104976828 3.87710152688447 0.000156898095091768 -52.3224824120604 30.778451409691 -1.69997124662308 0.0911816723825354 MPP6 other 0.000191184515903578 1 1 3.87710152688447 -1.69997124662308 0.324717976812598 4.46320602651403 3.37584753088508 1.32209940931304 0.188058018531976 11.7770272048423 12.1381386668513 0.970249848686012 0.33341434359442 ATP6V0A4 other 1 1 1 1.32209940931304 0.970249848686012 0.000480711036076712 153.602675107402 41.312198965429 3.71809487158841 0.000278861794005221 -99.585287382426 145.757134977191 -0.683227530494544 0.495470092258822 ZC3HAV1 other 1 1 1 3.71809487158841 -0.683227530494544 0.00114553383905921 48.4094466208671 16.0525341813241 3.01568874260288 0.00299132922799041 -88.8614281118116 56.6363313981715 -1.56898276985999 0.118665210066121 TTC26 other 1 1 1 3.01568874260288 -1.56898276985999 9.09476816622925e-07 495.93246170048 136.846475379468 3.62400610118228 0.000398955248685483 -591.876818937482 318.557013123708 -1.85799337184152 0.0651701751098632 OGDH essential 0.00832444130254963 1 1 3.62400610118228 -1.85799337184152 0.0231500189033672 -0.111474846906698 49.4181700525155 -0.00225574615143047 0.998203298467302 -190.937434899559 92.772205872835 -2.05813188447068 0.0413804864416634 ADAP1 other 1 1 1 -0.00225574615143047 -2.05813188447068 0.433471180379433 -3.4356276486921 10.6026727853516 -0.324034110855394 0.746360605977667 34.5573977388971 32.4871668674013 1.06372457407399 0.289151606799802 TFEC other 1 1 1 -0.324034110855394 1.06372457407399 0.00116447470857305 338.579930476181 144.995008772172 2.33511438320049 0.0208808791390083 -498.105610794737 340.490193754101 -1.46290736101042 0.145613149684821 H2AFV other 1 1 1 2.33511438320049 -1.46290736101042 0.212362751777828 14.7195247176178 47.0908646269305 0.312577074857953 0.755033257049463 -220.029273963042 143.314548560488 -1.53528916759052 0.126805482672352 CAV2 other 1 1 1 0.312577074857953 -1.53528916759052 0.442925384570509 32.9585610608369 112.604987408223 0.292691840916009 0.770162193914869 -368.608950810859 342.79250830992 -1.07531215494826 0.283961583504385 CAV1 other 1 1 1 0.292691840916009 -1.07531215494826 0.00548224174764654 127.617959860228 62.5012847676088 2.04184538501463 0.042918938256235 -330.561320670191 190.266636240631 -1.73735830517406 0.0843765227829826 MET other 1 1 1 2.04184538501463 -1.73735830517406 4.01699501449257e-07 21.0911035444482 5.33190917488978 3.95563818749486 0.000117055000389518 -37.3777469568537 15.4999261421877 -2.41147903634966 0.0170886559620685 RNF32 other 0.00379405179118823 1 1 3.95563818749486 -2.41147903634966 9.22045258282212e-08 259.45358098249 48.5676386214122 5.34210820923264 3.31982539090511e-07 -89.0038017540123 140.988292797847 -0.631285052026472 0.528808603445614 LMBR1 other 0.000920108963239819 1 0.00373845537269825 5.34210820923264 -0.631285052026472 0.250853925911053 -7.62183882386709 21.1023661921645 -0.361184084972288 0.718473449971308 -106.216044264439 64.1123766602066 -1.6567166871286 0.0996810530829841 WNT2 other 1 1 1 -0.361184084972288 -1.6567166871286 0.0454460215353133 20.9875050496775 8.59638399892379 2.44143410209514 0.0158248345465034 16.7161897605252 18.1224464759767 0.922402490341705 0.357840464592932 HOXA1 other 1 1 1 2.44143410209514 0.922402490341705 0.00498696528488921 220.984699765819 71.9843208858263 3.06990045952258 0.00253963730669543 -6.37940771118336 205.02249205051 -0.0311156480802687 0.975218399686323 DNAJB6 other 1 1 1 3.06990045952258 -0.0311156480802687 0.0162140698444657 27.8809933347667 9.93779779047056 2.80555047734037 0.00571310220436388 20.153631593322 21.0278587847471 0.958425287121518 0.339443694291687 HOXA2 other 1 1 1 2.80555047734037 0.958425287121518 0.00515261285435845 158.451730810578 48.1819110105686 3.28861449218613 0.00126359219361497 163.040828185743 101.950396060686 1.59921721234602 0.111949076562318 HOXA3 other 1 1 1 3.28861449218613 1.59921721234602 0.0981050974286601 8.15539707145706 37.189913844966 0.219290561022931 0.826727909606041 -107.557987742545 73.601689035917 -1.46135216666099 0.146053123496753 LFNG other 1 1 1 0.219290561022931 -1.46135216666099 0.20205438204119 61.9066867340357 39.7929093676674 1.55572155235114 0.121954280151252 12.3558200212683 84.19970867388 0.146744213440506 0.883537748269221 HOXA5 other 1 1 1 1.55572155235114 0.146744213440506 0.149770336932336 9.02827348957214 5.35697275791429 1.68533123044801 0.0940756039535005 1.5566544829069 11.3350733273297 0.137330781897431 0.890959849878517 HOXA6 other 1 1 1 1.68533123044801 0.137330781897431 1.85521484086737e-15 429.516843201528 69.3924940703269 6.18967294598502 5.70403310385083e-09 -139.295013990007 137.333062703028 -1.01428608121281 0.312112798982004 BRAT1 essential 2.50825046485269e-11 1 7.01253829787422e-05 6.18967294598502 -1.01428608121281 2.50368169709835e-12 312.469442382742 49.931407735156 6.25797381960727 4.04123807931209e-09 39.723202528312 98.5145213371969 0.403221799072106 0.687370935621312 IQCE other 3.14086868900988e-08 1 4.99658676126146e-05 6.25797381960727 0.403221799072106 0.285317381091143 -7.54893469885074 6.86401726522645 -1.09978375740605 0.273200072222912 -28.32853097112 19.2999552811641 -1.46780293313774 0.144265530753968 VIPR2 other 1 1 1 -1.09978375740605 -1.46780293313774 0.0333320494172931 113.522234648531 100.019401538728 1.13500213860582 0.258161050543429 -589.589520462954 309.356847111738 -1.90585573252238 0.0585566323151557 TSPAN12 other 1 1 1 1.13500213860582 -1.90585573252238 0.000131378970691114 243.87852494577 71.7759755899294 3.39777373893316 0.00086351228113483 -461.90265726681 256.251183030431 -1.80253863340002 0.0734035755482723 SSBP1 essential 0.948293410448462 1 1 3.39777373893316 -1.80253863340002 0.128278556844816 -19.4685109923518 9.6133091356582 -2.02516227426185 0.0446125426067033 -11.7890858221749 29.7430606432813 -0.396364246557052 0.692395894255406 CPED1 other 1 1 1 -2.02516227426185 -0.396364246557052 0.000179941824534064 114.206308318896 77.7146973861288 1.46955868272197 0.143761742141759 -423.336539922799 168.753250603981 -2.5086126543201 0.0131767711020797 HIBADH other 1 1 1 1.46955868272197 -2.5086126543201 2.45413997323858e-07 447.325028114647 120.037002589298 3.72655946471067 0.00027379051577408 -420.536290690252 260.65384104961 -1.61338996193887 0.108747727470277 TAX1BP1 other 0.00236088265425551 1 1 3.72655946471067 -1.61338996193887 0.0814541186065238 -14.4965767362308 83.8277878025788 -0.17293283189545 0.862935811140613 -360.927395383101 182.675790599107 -1.97578121435465 0.0500020275351897 CPVL other 1 1 1 -0.17293283189545 -1.97578121435465 0.000106960575281275 286.352807435287 75.5506416673047 3.79021013079243 0.000215551563448364 -37.6107780935556 185.396690170529 -0.202866502411456 0.839507159620244 GRB10 other 0.782095726456684 1 1 3.79021013079243 -0.202866502411456 0.0756129320618843 284.57525298988 136.918802880293 2.07842346707254 0.0394205724200608 -314.910554486912 547.472231017003 -0.575208269288697 0.566035856934095 ABHD11 essential 1 1 1 2.07842346707254 -0.575208269288697 0.00119231090247001 197.723533296922 58.5471884755191 3.37716529939944 0.000927380053272876 14.8230620721189 145.211534507052 0.102079095317315 0.918826687538719 COBL other 1 1 1 3.37716529939944 0.102079095317315 0.034133396748553 39.5450266644605 29.3403898783431 1.34780167640682 0.17972753322487 -73.3847522559788 63.8940256105784 -1.1485385613867 0.252550550085057 FKBP14 other 1 1 1 1.34780167640682 -1.1485385613867 3.23716945703771e-06 107.585032264634 25.8460915410181 4.16252616353597 5.25215726801482e-05 -21.7982563097405 56.2845566027775 -0.387286631101662 0.699085756827907 PLEKHA8 other 0.028069496361974 1 0.495908689245959 4.16252616353597 -0.387286631101662 0.00119127787742966 57.8321987120515 15.6839070359478 3.68735918795611 0.000318873177672562 -2.10776114409974 62.7123769373058 -0.0336099705837476 0.973234076906406 STX1A other 1 1 1 3.68735918795611 -0.0336099705837476 0.00151896755651486 38.4315698883604 13.9690565775458 2.75119294384821 0.00666977659613719 -16.3487286143449 30.0674117809782 -0.54373581382511 0.587430510121146 NOD1 other 1 1 1 2.75119294384821 -0.54373581382511 8.92880161361996e-07 434.647608026205 130.519361411192 3.33013894127843 0.00109262530970838 -620.593603096457 304.000194313877 -2.04142502111594 0.0429612156671778 GARS essential 0.00817788939791452 1 1 3.33013894127843 -2.04142502111594 4.21602455641879e-08 332.234753043319 55.2080146144206 6.01787177756141 1.29834254532744e-08 -41.7089164465768 223.273250708245 -0.186806598256942 0.852064694739064 EPHB6 other 0.000431130671139385 1 0.000157216298813699 6.01787177756141 -0.186806598256942 3.52711063074703e-07 91.0337853269677 24.4786218317846 3.71890974714777 0.000282713170503878 -112.8801406448 60.7592090685399 -1.85782768365968 0.0651669835826322 MINDY4 other 0.00334511172220048 1 1 3.71890974714777 -1.85782768365968 1.89681193984777e-06 246.011530301291 56.8819503034872 4.32494893351449 2.78019946689744e-05 -442.767661096526 233.194988360729 -1.89870144383896 0.0595369781135458 CASP2 other 0.0168673335939553 1 0.2702631901771 4.32494893351449 -1.89870144383896 0.59641311858861 -286.563438977179 443.945721899069 -0.645492060946876 0.519594524068836 -1130.54732905842 1136.23236603744 -0.994996589475047 0.321340300898661 CHCHD2 other 1 1 1 -0.645492060946876 -0.994996589475047 0.394820121419752 -10.9254060659549 1923.18021846489 -0.00568090601237347 0.995474815521003 -9317.21811300259 7038.73551507169 -1.32370623857824 0.187601144570389 HSPB1 other 1 1 1 -0.00568090601237347 -1.32370623857824 0.35973660244816 -329.735448122043 237.416321624316 -1.3888491147791 0.166896992857847 -548.618773904634 766.226330695857 -0.716000941140198 0.475082136086234 NPTX2 other 1 1 1 -1.3888491147791 -0.716000941140198 5.53007122905339e-11 407.213072885036 62.7675067856886 6.48764135678371 1.12738663457165e-09 -355.23315973811 206.943175230956 -1.71657344747734 0.088067772635202 PDAP1 essential 6.61562421131657e-07 1 1.41983072757954e-05 6.48764135678371 -1.71657344747734 0.00119556925785247 222.507855545013 78.8277998110581 2.82270792890758 0.00539112073616387 -441.435353869454 264.004040443886 -1.67207802246982 0.09653949808737 BUD31 essential 1 1 1 2.82270792890758 -1.67207802246982 1.24852139477231e-09 244.762323378554 43.0703595632079 5.68284838716876 6.44548814079404e-08 -324.007269019217 144.095828671668 -2.24855411850602 0.0259598737464924 PTCD1 other 1.40233923060826e-05 1 0.000756829217492036 5.68284838716876 -2.24855411850602 0.933651216964156 -6.58970992593327 22.2751167903245 -0.29583278902473 0.767753739305388 -21.7238825996845 73.4254202407123 -0.295863238214594 0.767730528400439 CYP3A5 other 1 1 1 -0.29583278902473 -0.295863238214594 2.97265129668027e-15 586.008817766167 69.8489033735483 8.38966382381441 2.65548067308047e-14 -261.320509470933 229.910991441916 -1.13661599139749 0.25743073445491 ZKSCAN1 other 4.00148591046131e-11 1 3.67571634767798e-10 8.38966382381441 -1.13661599139749 1.05793886785746e-13 1086.62209450058 192.043319046327 5.65821346921446 7.67384000421109e-08 -384.695045072298 375.372729885485 -1.0248348226832 0.307113274985671 EIF3B essential 1.37891752036541e-09 1 0.00089684168129215 5.65821346921446 -1.0248348226832 1.24354850801524e-07 29.516287733577 20.0415710693734 1.4727531904264 0.142955516487309 -129.67393077959 39.2571413144862 -3.30319341749266 0.00120047830174936 NUDT1 other 0.00122738237741104 1 1 1.4727531904264 -3.30319341749266 1.97839635482791e-18 638.38795978278 67.7844496935178 9.41791166955256 6.17511840687551e-17 -336.381932605386 222.975318578622 -1.50860613071296 0.133435111790391 TAF6 essential 2.76896353821714e-14 1 8.72852986811853e-13 9.41791166955256 -1.50860613071296 5.0685960613763e-08 309.696166671185 61.7417689649449 5.01599114931451 1.44602671763184e-06 -341.898473717028 190.327407667987 -1.79637014924012 0.0744086327148354 WASL other 0.000515172103678287 1 0.0156431170313413 5.01599114931451 -1.79637014924012 1.32627702943457e-10 149.06430453046 44.5449005423813 3.34638314858591 0.00103325976589161 -211.229181004818 86.6376094761012 -2.43807720783299 0.015926301026865 AIMP2 other 1.56182382986214e-06 1 1 3.34638314858591 -2.43807720783299 0.404311032016179 -17.8477621563452 22.972493531085 -0.776918802140253 0.43842205684588 -100.194302068307 77.2331131914375 -1.29729720748088 0.196507496577884 TFR2 other 1 1 1 -0.776918802140253 -1.29729720748088 0.00165210984824602 118.13287359561 32.6222276772919 3.62123870767543 0.000396668942171216 60.1990037174105 112.307438007875 0.536019739967617 0.592713283893425 FSCN3 other 1 1 1 3.62123870767543 0.536019739967617 1.60572753647483e-09 198.166197405224 32.1897543915169 6.15618854977804 6.41730828048596e-09 -81.029626090627 108.221379675678 -0.748739540499851 0.455178915428757 MOSPD3 other 1.7929553672278e-05 1 7.87788764512457e-05 6.15618854977804 -0.748739540499851 0.722210556810667 176.680356422233 226.270310608627 0.780837556403199 0.436120458255429 46.0619749799382 760.716745330714 0.0605507572465927 0.951797058330239 PCOLCE other 1 1 1 0.780837556403199 0.0605507572465927 0.0098021889132503 5.84217740401787 2.57799330433739 2.26617245056013 0.0248617473785598 -10.7596005324997 8.66716747188282 -1.24142063337358 0.216375374069361 FBXO24 other 1 1 1 2.26617245056013 -1.24142063337358 2.60606041126454e-15 272.870613004493 31.0096350929309 8.79954285778418 2.4330047416066e-15 -65.8081303665827 109.145523564965 -0.602939343888095 0.547424581884261 RBM28 essential 3.5129694343846e-11 1 3.40231383066267e-11 8.79954285778418 -0.602939343888095 7.30896972705619e-16 179.19193820158 31.1782520391158 5.747337534406 4.85185941134312e-08 -91.8072952512045 60.6401449194473 -1.51396892888628 0.132124053971768 USP42 other 9.94677690155076e-12 1 0.00057295607788551 5.747337534406 -1.51396892888628 0.000141519337527536 209.110551346881 48.4253357360158 4.31820550479648 2.7865254802922e-05 98.9452036768988 170.444076716064 0.580514181444553 0.562405557547577 IMPDH1 other 1 1 0.270822411429599 4.31820550479648 0.580514181444553 0.00134703279703713 126.660895725448 52.9463830869116 2.39224831500829 0.0179752632698732 -332.437625450905 175.33546094009 -1.8960090769345 0.059869173520684 AGFG2 other 1 1 1 2.39224831500829 -1.8960090769345 5.49337171573271e-10 166.802529819616 39.8395456760768 4.18685823316954 4.74206654275931e-05 -276.366328971313 99.9913645572596 -2.76390196488471 0.00640863377925702 LSM5 essential 6.28441724279822e-06 1 0.449879852911576 4.18685823316954 -2.76390196488471 0.36543862571697 -129.97043347532 177.262090529933 -0.733210542010236 0.464551949100804 556.741794036581 577.15357842143 0.964633703838974 0.336250512836187 SERPINE1 other 1 1 1 -0.733210542010236 0.964633703838974 0.000209770290016786 81.8654631161511 37.7199086026351 2.1703515768973 0.0315125542568434 -358.910918417399 124.628703295606 -2.87984155276093 0.00454582880165243 AP1S1 other 1 1 1 2.1703515768973 -2.87984155276093 5.49728458015623e-08 172.43511157935 47.8793198972099 3.6014528182427 0.000427941907750444 -113.165558854516 91.2554161273709 -1.24009690226565 0.216850512788305 C1GALT1 other 0.000557644547811048 1 1 3.6014528182427 -1.24009690226565 0.000248021471462399 247.644727465571 64.8556586206992 3.8183981588082 0.000193820911533371 -126.472415107472 213.566032951841 -0.592193493316384 0.554583885819851 PLOD3 other 1 1 1 3.8183981588082 -0.592193493316384 6.28082613619173e-06 -28.2452802816359 46.6533169872155 -0.605429197871955 0.54579675008138 -369.914121436033 89.2008534114834 -4.14697962282513 5.58264763685291e-05 RPA3 essential 0.0528594327621896 0.803063862561292 1 -0.605429197871955 -4.14697962282513 0.00550379187119907 243.753418073946 121.822486802684 2.00089018432824 0.0471500179321306 -779.904492799257 401.154591350855 -1.94414948654331 0.0536882570155819 ZNHIT1 other 1 1 1 2.00089018432824 -1.94414948654331 0.115797553984276 68.9714870486071 38.8772466470746 1.77408363495302 0.0780126428760347 -73.2803400672843 128.020584712034 -0.572410602811408 0.567873159359463 CLDN15 other 1 1 1 1.77408363495302 -0.572410602811408 1.29239482157989e-07 45.1612731633719 17.2129694288748 2.62367706803764 0.00958557944040247 -71.5114752988511 32.9110910425118 -2.17286856903281 0.0313391983296228 GLCCI1 other 0.00127417205459561 1 1 2.62367706803764 -2.17286856903281 2.00312608912228e-11 180.131236489408 53.6147661217261 3.35973183358556 0.000985028074131171 -298.503422683384 101.827467802789 -2.93146269002289 0.00389171862146095 PHF14 other 2.4358013243727e-07 1 1 3.35973183358556 -2.93146269002289 0.00909575889944431 28.959024632499 10.4097902464218 2.78190279986221 0.00607554031480757 -24.2415494636472 36.2715928669809 -0.66833429545122 0.50491426398106 NRF1 essential 1 1 1 2.78190279986221 -0.66833429545122 9.46223238905518e-14 220.954371036094 100.434847280163 2.19997716947527 0.0293081749654071 -935.662596171484 189.730886709606 -4.93152492141972 2.10419170287758e-06 TMEM106B other 1.23519981606726e-09 0.0306728024528465 1 2.19997716947527 -4.93152492141972 0.362688155020824 48.1332024144205 42.4872228023182 1.13288653010745 0.259198350241284 -72.8071026955513 144.142297611906 -0.505105745515307 0.61427877980349 EZH2 other 1 1 1 1.13288653010745 -0.505105745515307 0.000417286814787306 94.8944952795931 28.1606257472238 3.36975804910685 0.000950891314177072 -150.752350520455 103.843320887009 -1.45172890497683 0.148611174273468 CEP41 other 1 1 1 3.36975804910685 -1.45172890497683 2.74596994599715e-06 241.507221759094 48.2898622004977 5.00119923217765 1.7528172027761e-06 -35.9685728696008 144.531991309389 -0.248862362884114 0.803848275844424 ZNF862 other 0.0239997773280151 1 0.0188603131018708 5.00119923217765 -0.248862362884114 0.299143600441549 -492.768024293273 325.178910708499 -1.5153750998785 0.131714093619991 -357.804875649035 745.535752782959 -0.479929868303982 0.631953819015219 SFRP4 other 1 1 1 -1.5153750998785 -0.479929868303982 0.294930605217272 1140.94989453147 740.909792304353 1.53993091518325 0.125656410182814 235.619745313037 2790.31887558154 0.08444187056002 0.932816232496877 MEST other 1 1 1 1.53993091518325 0.08444187056002 0.928739332436272 -0.0971456244592071 6.85314773043412 -0.0141753291013695 0.988708450190325 -4.82175942780411 15.2729953017056 -0.315704898256968 0.752653949445272 MEOX2 other 1 1 1 -0.0141753291013695 -0.315704898256968 7.57415331540812e-15 100.757802832869 16.6178131828121 6.06324079615262 1.00009742499843e-08 -63.7593996916886 37.1361177802003 -1.71691074627308 0.0880190801482026 ANKMY2 other 1.01266429827007e-10 1 0.000121711856622309 6.06324079615262 -1.71691074627308 2.75989672278642e-07 58.7938165282117 10.4333007840275 5.63520766296895 9.27405611453944e-08 10.0696108251173 32.2534559383927 0.312202538678373 0.755351111985884 ACTR3C other 0.00264177314305117 1 0.00107940739117125 5.63520766296895 0.312202538678373 0.00464223899658534 28.6106160430551 12.8645064651719 2.22399639819162 0.0275942144170715 -28.9581419430841 29.7416975746289 -0.973654643297388 0.331745086954195 POU6F2 other 1 1 1 2.22399639819162 -0.973654643297388 9.29063127554336e-05 -80.1658901278176 71.630598090325 -1.11915706785988 0.264827068981451 -659.102485846024 160.074150436343 -4.11748232959157 6.24637151164829e-05 TSPAN13 other 0.684254993443768 0.897915904799442 1 -1.11915706785988 -4.11748232959157 0.0143323412350476 672.631125676395 264.078004803603 2.54709257659166 0.0119429140599359 -566.242906929212 816.369475829849 -0.693611071572244 0.489075349763286 RARRES2 other 1 1 1 2.54709257659166 -0.693611071572244 0.0437297318254786 -127.147387995216 95.7105123263129 -1.32845791862155 0.186004957395053 -538.61779771739 213.885955958966 -2.51824761145478 0.0128222824316089 AGR2 other 1 1 1 -1.32845791862155 -2.51824761145478 6.58995848820253e-06 204.176982903117 97.5891966597508 2.09220887036287 0.0380603609404508 -547.639490445861 222.665343392762 -2.45947340570137 0.0150205099635086 AHR other 0.0553556513009013 1 1 2.09220887036287 -2.45947340570137 0.125901104042989 134.519403278655 188.331440930438 0.714269495385746 0.476141789124706 -1221.29351050008 697.93993107724 -1.74985475987176 0.0821351905862399 CHCHD3 other 1 1 1 0.714269495385746 -1.74985475987176 0.788706352268892 -2.15991896073827 7.70184199712143 -0.280441868522561 0.779517356694359 -17.0881747242105 24.9926730411284 -0.683727374662563 0.495181525909004 GIMAP2 other 1 1 1 -0.280441868522561 -0.683727374662563 0.902757633015261 78.6668818808236 199.229813808251 0.394854968627018 0.693499831951467 209.679755769038 646.505809703122 0.324327720837225 0.746132910162945 TMEM176B other 1 1 1 0.394854968627018 0.324327720837225 0.0533356561085947 330.915227100362 151.145000698375 2.18938916650467 0.0300936109720031 69.3027289012355 346.788296852728 0.199841602297977 0.841871571424832 GLI3 other 1 1 1 2.18938916650467 0.199841602297977 0.000515079505514562 57.2203110273334 121.839217053998 0.469637875315417 0.639282391236018 -886.205735828731 278.570208818497 -3.18126528887424 0.0017757607058651 PSMA2 other 1 1 1 0.469637875315417 -3.18126528887424 0.000367278672580813 -27.2509425070685 44.5501987907314 -0.611690705019661 0.541650271284578 -386.242358960549 101.858485963017 -3.79195071779082 0.000214650549401787 MRPL32 essential 1 1 1 -0.611690705019661 -3.79195071779082 0.00380424737798815 55.8193879212111 48.3024343008382 1.15562266641792 0.249648820549651 -244.950605799865 111.171266593027 -2.2033625531728 0.0290738405189894 COA1 other 1 1 1 1.15562266641792 -2.2033625531728 0.180954995669216 -60.510052091812 51.1342257359641 -1.18335715894596 0.23851509204668 -215.661449733727 117.688823008703 -1.83247180335704 0.0688380851582526 BLVRA other 1 1 1 -1.18335715894596 -1.83247180335704 1.68944284398911e-10 117.100154647566 30.9039575163369 3.7891637207197 0.000217348751564266 -247.085428245855 71.1275145768096 -3.47383751162893 0.000668603656629495 URGCP other 1.97935123601764e-06 1 1 3.7891637207197 -3.47383751162893 0.00158235753850328 409.132676141143 128.854291236173 3.17515755366856 0.00181117597854343 -346.705984977728 410.365404674372 -0.844871378114444 0.399501866725231 RHEB other 1 1 1 3.17515755366856 -0.844871378114444 0.00028614685650538 124.481164264595 34.7731530694041 3.57980664037402 0.000461124099584273 -108.400587458797 110.74290886421 -0.97884901679542 0.329199804841819 PRKAG2 other 1 1 1 3.57980664037402 -0.97884901679542 9.44908372981406e-06 474.317799973541 174.023196218368 2.72560101343247 0.00719304345306398 -868.111092737134 384.480568320101 -2.25788027865789 0.0254158229720742 POLD2 essential 0.0782497628054844 1 1 2.72560101343247 -2.25788027865789 0.411216545460425 24.5353419764519 22.8743884245581 1.07261193265874 0.285191117339086 -7.62637253604979 50.5378481292401 -0.150904180101751 0.880256786867474 GCK other 1 1 1 1.07261193265874 -0.150904180101751 0.00572401619991657 160.541045296167 49.1997870308713 3.26304350048168 0.00137265481107351 70.9981543659592 195.718517917198 0.362756447992295 0.717311443892701 BCL7B other 1 1 1 3.26304350048168 0.362756447992295 1.2218572767663e-06 367.390501389073 88.9022061498443 4.13252400924492 5.98235577376e-05 -199.792631300437 196.417325323181 -1.01718435973865 0.310725677631398 YKT6 essential 0.0110614739265653 1 0.560546736001312 4.13252400924492 -1.01718435973865 0.000363583130180525 137.068013937282 40.8732584653833 3.35348878664443 0.00101665137413304 -276.197584204414 162.595288558299 -1.69868134958524 0.0915092364211772 TBL2 other 1 1 1 3.35348878664443 -1.69868134958524 0.00432700403716097 200.724761904762 61.5718834507447 3.26000685142813 0.00138444619777463 -53.5146320346319 252.844692761856 -0.21165020886966 0.832673092972835 CLIP2 other 1 1 1 3.26000685142813 -0.21165020886966 2.13036097698414e-05 446.941774891774 128.888901602356 3.46765135970097 0.000688852479584312 -1402.79307359307 529.281758160454 -2.65037109623531 0.0089209403987944 EIF4H other 0.169981502353564 1 1 3.46765135970097 -2.65037109623531 4.30376579908938e-05 319.720217541436 73.9462811158064 4.32368217464143 2.81558245200712e-05 -268.119027812658 303.995568554258 -0.881983343006537 0.379225730943672 LIMK1 other 0.330098836790156 1 0.273505679387971 4.32368217464143 -0.881983343006537 4.07032544768527e-10 36.7964725045785 6.70175928412553 5.49056910947822 1.70021465992546e-07 -10.8785209810893 16.1549949468189 -0.673384362972603 0.50175299597973 SPATA6L other 4.68779381809913e-06 1 0.00195065627933248 5.49056910947822 -0.673384362972603 0.000270592245317061 11.8528557845767 9.285245366849 1.27652585540656 0.203755691790437 -57.7797378518796 22.2803380505812 -2.59330615723635 0.0104535483536165 SLC1A1 other 1 1 1 1.27652585540656 -2.59330615723635 0.0266125254379078 40.6192201291003 15.9957649463651 2.53937340697988 0.0120773255511723 49.4459228033198 22.9616186625319 2.15341625213924 0.032812372517945 LHX2 other 1 1 1 2.53937340697988 2.15341625213924 1.09145527418528e-08 116.522522522522 29.992662085174 3.88503435245656 0.000150504526809478 -115.499044499045 47.0401640657658 -2.45532826666098 0.0151665272440762 FKTN other 0.000116087182962346 1 1 3.88503435245656 -2.45532826666098 0.00315881951297729 29.4215267899478 16.2956108676166 1.8054878107341 0.0729142737745697 -41.7007773323563 25.557858338406 -1.63162252408654 0.104763287581133 FSD1L other 1 1 1 1.8054878107341 -1.63162252408654 0.572029219261296 -1.75544030664103 5.01830829821342 -0.349807186470785 0.72700535059997 -12.2325789768019 11.6967743814402 -1.04580789351737 0.297439270204033 CNTNAP3 other 1 1 1 -0.349807186470785 -1.04580789351737 1.95203866094332e-08 1201.81640751277 220.336657892563 5.45445510069768 1.90301782859814e-07 51.3504423396047 328.111924579527 0.156502822643248 0.875840352652976 SPIN1 other 0.000204515090507031 1 0.00217572028343625 5.45445510069768 0.156502822643248 0.000648803763935184 -28.7117692772644 21.4654480546512 -1.33758071129771 0.182992508174848 -122.255288835161 31.284651049574 -3.90783610280434 0.000138798489084048 NMRK1 other 1 1 1 -1.33758071129771 -3.90783610280434 3.25507316791525e-14 699.728392900457 115.471205967093 6.05976517730199 9.62779903255228e-09 -508.838347236429 185.602775458971 -2.7415449255979 0.00682041830297816 TMEM245 other 4.29767310359851e-10 1 0.000117266592216487 6.05976517730199 -2.7415449255979 0.0799240946874886 344.048584496158 160.42603233766 2.14459324015453 0.0335338411348668 365.270285006458 232.554449223382 1.57068714972465 0.118281407857032 PRUNE2 other 1 1 1 2.14459324015453 1.57068714972465 0.00167517643447775 89.0133037992279 51.962547570502 1.7130280935217 0.088706835822212 -168.690490496325 84.8247156239396 -1.98869503134198 0.0484951460836972 MEGF9 other 1 1 1 1.7130280935217 -1.98869503134198 0.000111798036604572 237.76594922026 115.196530859554 2.06400268693978 0.040673715678792 -382.10803582936 172.14597863935 -2.2196744812139 0.0278832899558449 TRIM14 other 0.81567847506696 1 1 2.06400268693978 -2.2196744812139 3.00993044874084e-09 254.686718649311 76.4427191723277 3.33173285051727 0.00107763979342417 -363.50594470937 114.233532933531 -3.18212993483167 0.00176454215017231 CORO2A other 3.31333143797391e-05 1 1 3.33173285051727 -3.18212993483167 3.37534643694948e-06 194.922388735503 45.858782757526 4.25049198898576 3.6355737308332e-05 -26.0546804861992 68.0653708182091 -0.382789077220878 0.702390630182011 TGFBR1 ts 0.0292271247975456 1 0.348724232261521 4.25049198898576 -0.382789077220878 0.000207616118060026 72.0001934235973 136.527390867303 0.527368119805187 0.598687187584895 -674.070287986246 202.855628004777 -3.32290651541782 0.00110996731841367 SEC61B essential 1 1 1 0.527368119805187 -3.32290651541782 0.000480777371796514 32.8328802751252 10.7602578322593 3.05130980938878 0.00267855167811035 -11.0513535603586 16.1202105152936 -0.685558885839235 0.494008819069422 C5 other 1 1 1 3.05130980938878 -0.685558885839235 0.172385753520512 -48.9224833391794 38.3281163395493 -1.27641240977705 0.203718921653969 28.2171593167732 57.6161821221376 0.489743649743351 0.625007732976449 OGN other 1 1 1 -1.27641240977705 0.489743649743351 0.373267259215211 -58.9198259788689 61.235947229488 -0.962177097678604 0.337469003612911 -127.693652318264 92.262543059534 -1.38402484999646 0.168353356116451 ASPN other 1 1 1 -0.962177097678604 -1.38402484999646 0.539632226623755 -15.9266625233064 16.29127946044 -0.977618888803727 0.329796084738087 -23.8858208292639 24.5456294989743 -0.973119097648814 0.332020130262534 ECM2 other 1 1 1 -0.977618888803727 -0.973119097648814 0.0418120629204142 101.179544878914 59.5308697422745 1.69961475982037 0.0912093393421305 203.862418090543 81.9025907291195 2.48908387727059 0.0138636791562351 TLE4 other 1 1 1 1.69961475982037 2.48908387727059 0.332685204930659 12.7806026749307 14.7422145304425 0.866939132417243 0.38730686933412 -13.9497685940303 21.9135939031762 -0.636580592652509 0.525331037648224 LHX6 other 1 1 1 0.866939132417243 -0.636580592652509 1.04287186512406e-08 368.008917224236 94.3010271149298 3.90249108077819 0.000140945240702316 -390.129130377901 146.726174483527 -2.65889253741635 0.00865217782859772 PTGR1 other 0.000111024138761107 1 1 3.90249108077819 -2.65889253741635 2.26517455570763e-07 54.1426563598034 15.6435024877121 3.46103159457621 0.000693243211033449 -60.0196743968142 24.5350437512544 -2.44628356913957 0.0155376724400769 SUSD1 other 0.00218611996371344 1 1 3.46103159457621 -2.44628356913957 3.38710927169194e-05 253.394910435578 70.1384032901766 3.6127841317863 0.000406582316679093 -98.507546721113 113.940184643986 -0.864554915624425 0.388593805982793 AKNA other 0.263821941172085 1 1 3.6127841317863 -0.864554915624425 0.296000634493404 11.5120402344502 14.5994740109062 0.788524314358883 0.431571594668378 37.415956655156 23.897444883522 1.56568858459657 0.119422185688616 TNFSF8 other 1 1 1 0.788524314358883 1.56568858459657 3.54792554908217e-05 479.457013663555 120.300614792394 3.9854909676976 0.000103670002286404 51.9751220486491 166.796463121826 0.311608058563492 0.755759859347469 DNM1 other 0.275425460375249 1 0.947232810890875 3.9854909676976 0.311608058563492 0.599003317327803 -4.21235370102248 205.552838100907 -0.0204928024343532 0.983676954430966 235.10251692958 282.208449037018 0.833081070860289 0.40609759579497 ENG other 1 1 1 -0.0204928024343532 0.833081070860289 0.00188559111883994 -143.511606059419 150.501563197629 -0.953555584475683 0.34181271989273 -709.313383176107 206.627225972912 -3.43281665732228 0.000768570553659695 AK1 other 1 1 1 -0.953555584475683 -3.43281665732228 1.77882748929898e-16 88.4835615590206 14.3081743724569 6.18412658776025 5.86538993231574e-09 -91.9526350005678 34.3971999976019 -2.6732593061929 0.00836114585197283 CDC37L1 other 2.43948401882462e-12 1 7.20915076580928e-05 6.18412658776025 -2.6732593061929 0.0224348592607543 0.836450744897281 3.61618654432866 0.231307410346157 0.817399840668539 -18.5379175690753 8.5968592233626 -2.15635932698504 0.0326933255531497 RLN2 other 1 1 1 0.231307410346157 -2.15635932698504 7.10148617475055e-08 45.5097952352825 23.8292739911335 1.9098271836656 0.0581166123574142 -207.170456782831 56.6499851115236 -3.65702579400483 0.000355459799811937 PLGRKT other 0.000715474732106118 1 1 1.9098271836656 -3.65702579400483 2.2722276567852e-11 318.56693254148 54.1937095940921 5.87830091218204 2.48184091763794e-08 -44.3486178060665 73.6611872394939 -0.602062218490673 0.548018112994103 TBC1D13 other 2.75871159810292e-07 1 0.000297001902613733 5.87830091218204 -0.602062218490673 1.18342397534527e-19 214.503204323016 22.9863156898336 9.33177840317779 1.30407624070576e-16 36.5544145317327 53.9727951380798 0.677274809248155 0.499274831999906 RIC1 other 1.66862780523683e-15 1 1.83913872226733e-12 9.33177840317779 0.677274809248155 1.31119047195272e-14 119.724639057751 17.0994391006508 7.00167054328666 7.47659115628554e-11 -29.3760195035462 40.5736161428496 -0.724017780424613 0.470160417617469 KDM4C other 1.74493228007467e-10 1 9.77639059595897e-07 7.00167054328666 -0.724017780424613 0.82021379831997 -2.03847072375036 25.3140969794965 -0.0805270962421232 0.935929855475475 -37.7273959227742 65.2214634744509 -0.578450619059677 0.56386351882952 DOCK8 other 1 1 1 -0.0805270962421232 -0.578450619059677 2.4679688109794e-09 237.32373546129 54.6644426049131 4.34146447218983 2.65224940561395e-05 -314.780596688322 140.842272572287 -2.23498663390823 0.026957854401647 KANK1 other 2.72833952053773e-05 1 0.258541272059248 4.34146447218983 -2.23498663390823 8.61014038334376e-06 298.723582561001 132.508965214069 2.25436506940049 0.0255476694589869 -422.479009292475 182.991895187468 -2.30873071651431 0.0222544267523922 NCS1 other 0.0715933172875033 1 1 2.25436506940049 -2.30873071651431 1.31563537819502e-15 289.254005380221 49.144499483886 5.88578596624154 2.82826674501197e-08 -448.986558853223 127.786949192906 -3.51355566189657 0.00059705315516868 TESK1 other 1.78268593745425e-11 1 0.000337525353349729 5.88578596624154 -3.51355566189657 0.0425442753946573 113.041423503833 45.5453994979949 2.48195042199179 0.0141999722864353 115.954857535187 65.9607244012363 1.7579379030139 0.0808537061613414 KCNT1 other 1 1 1 2.48195042199179 1.7579379030139 0.226478793260657 -149.952908587255 139.28144128012 -1.07661801320446 0.283502691942232 -619.677529737655 362.833546258256 -1.70788378342664 0.0898743617700656 CA9 other 1 1 1 -1.07661801320446 -1.70788378342664 6.9017076676454e-09 302.185396598882 61.6062612303995 4.90510851597937 2.30157071066175e-06 -52.5161533277836 85.076858609172 -0.617278942667987 0.537939317690512 FUBP3 other 7.43244898728733e-05 1 0.0245738704777355 4.90510851597937 -0.617278942667987 0.0599403576654984 11.3980235105061 7.88105293710214 1.44625643317873 0.150164176462718 -15.8163267269926 18.6457412004764 -0.848254116419277 0.397630282125406 TYRP1 other 1 1 1 1.44625643317873 -0.848254116419277 1.87433708930059e-10 169.806145805173 50.0560795394138 3.39231812334541 0.000909646042335338 -534.886657655221 130.653988335489 -4.09391756401464 7.26419607326342e-05 CREB3 other 2.19259952706383e-06 1 1 3.39231812334541 -4.09391756401464 4.75726703776899e-23 474.511262986028 45.1711544388179 10.5047406664961 3.10957127757247e-19 -99.3423615425735 118.019664992884 -0.841744141101937 0.401419812902217 RGP1 essential 6.8143093049003e-19 1 4.44233352714002e-15 10.5047406664961 -0.841744141101937 4.79106460912085e-12 205.863669181442 29.9811622816988 6.86643390430215 1.60281756023382e-10 26.6857604207068 71.0658210684373 0.375507663452 0.707809917145689 MPDZ other 5.95098135098901e-08 1 2.07596930401485e-06 6.86643390430215 0.375507663452 3.58771440789927e-06 554.829695922773 114.538740966381 4.84403522547559 3.0734203803286e-06 155.522246443694 277.679876648126 0.560077483183163 0.576240390108031 DDX58 other 0.0309727384833944 1 0.0325352281461586 4.84403522547559 0.560077483183163 0.033263958258006 178.455354494216 304.852279598343 0.585383041023474 0.559362641382999 -936.311759470918 475.44273549265 -1.96934707289348 0.0511611693826762 EDF1 other 1 1 1 0.585383041023474 -1.96934707289348 0.313396485452939 -0.268524227415016 13.845440226814 -0.019394415996609 0.984551734018999 -36.5412410684314 25.3486348699873 -1.44154670481668 0.151473937182729 PIP5K1B other 1 1 1 -0.019394415996609 -1.44154670481668 1.39134119225994e-07 290.366098419149 56.7083282957953 5.12034311617468 9.28615425068383e-07 57.6220476733231 136.4028406409 0.422440232201773 0.673312687336333 GLIS3 other 0.00136894059906456 1 0.0101655530582236 5.12034311617468 0.422440232201773 1.60364488408142e-05 149.883701352627 77.862419120157 1.92498130736636 0.0561242416596671 -592.28681614962 191.403139235929 -3.09444671865884 0.00235283973936092 BAG1 other 0.129638652429142 1 1 1.92498130736636 -3.09444671865884 1.69218436679054e-07 767.535786875727 152.574652678657 5.03055896507438 1.31579960040416e-06 108.100742837786 212.383386078334 0.508988696497732 0.611470204679078 RAPGEF1 other 0.00165258725260764 1 0.0142685308667827 5.03055896507438 0.508988696497732 0.54318927875655 -46.3565060208219 270.756176452968 -0.17121125962153 0.864343641463344 -440.917747152683 423.606772780315 -1.0408656694952 0.300013204843486 NPDC1 other 1 1 1 -0.17121125962153 -1.0408656694952 0.00163009127299127 48.2427530841089 13.3798820369633 3.60561871553376 0.000420098017982964 13.8985215795629 24.731251760571 0.561982131519978 0.574945216080116 APBA1 other 1 1 1 3.60561871553376 0.561982131519978 4.93538414821762e-08 448.957317073171 78.9677449184801 5.68532528738966 6.14661180166334e-08 165.17987804878 109.922826382439 1.50268950940265 0.134915182746562 SETX other 0.000502027275556696 1 0.000722607149425956 5.68532528738966 1.50268950940265 3.54273731771138e-09 23.7394339539801 4.12992540077817 5.748150789723 4.69567517816867e-08 2.50450029250419 9.61733113743521 0.260415312389056 0.794891307175169 SH3GL2 other 3.88213155274813e-05 1 0.000554794022300628 5.748150789723 0.260415312389056 0.75218926127135 855.449421536636 1812.22251198262 0.472044363139906 0.63773149557113 -807.844150801818 2826.31322145135 -0.285829661295282 0.775489399280033 PTGDS other 1 1 1 0.472044363139906 -0.285829661295282 0.000225528347279603 868.963562477915 228.432928051173 3.8040205932275 0.000224648805363622 67.4828073608956 357.390685288111 0.1888208342825 0.850549580658433 ABCA2 other 1 1 1 3.8040205932275 0.1888208342825 0.000558798298281952 95.2003695733008 39.634972703198 2.40192847579833 0.0175574860799284 -146.337175543562 88.6186775186631 -1.65131301482968 0.100809389683743 SHB other 1 1 1 2.40192847579833 -1.65131301482968 9.58263352177682e-25 607.365845878742 65.06942684418 9.33412011347793 1.22785120498885e-16 -576.596185631781 166.410640826528 -3.46489973698763 0.000690664310326948 UBE2R2 other 1.3790367901189e-20 1 1.73212969487778e-12 9.33412011347793 -3.46489973698763 3.46604691010047e-11 91.4197083432943 14.1159818397741 6.47632657656899 1.1791643006872e-09 -38.0153191489362 25.8546013904096 -1.47035023185612 0.143493964277409 ABHD17B other 4.17866615481713e-07 1 1.48386035598477e-05 6.47632657656899 -1.47035023185612 2.75192288344803e-12 82.3077531158986 20.3978529451659 4.03511846747599 8.69350101772412e-05 -190.74415622004 45.0903043042077 -4.23026988092959 4.05931507245221e-05 EXOSC3 essential 3.44788418067204e-08 0.584866115638915 0.800149833671328 4.03511846747599 -4.23026988092959 2.71649485601091e-08 822.847109760509 159.148659477405 5.17030499950476 7.11618116335022e-07 -464.38985526575 292.511094638097 -1.58759740665668 0.114415253843723 ZFAND5 other 0.000281700516568331 1 0.00784487811447728 5.17030499950476 -1.58759740665668 0.000545490232937439 276.535891317576 296.09658022011 0.933938146506141 0.351760890403395 -1423.55472750767 526.251692162867 -2.70508342055289 0.0075780626587558 PDLIM1 other 1 1 1 0.933938146506141 -2.70508342055289 1.16767995759427e-06 55.2348276441605 15.8298233517293 3.48928894636885 0.000627693683409651 -42.2314309470948 28.0381041003058 -1.50621564125779 0.134008481982981 CCNJ other 0.0105920248953377 1 1 3.48928894636885 -1.50621564125779 0.641071653332167 -11.03122169276 12.7413749651985 -0.865779535010184 0.387932157043425 -30.9860637275147 44.2336270968645 -0.700509222534709 0.484646170933697 GATA3 other 1 1 1 -0.865779535010184 -0.700509222534709 0.185468412617881 -22.2970920471003 12.2841715429351 -1.81510751206694 0.0714530931344592 -15.4308277163774 23.4150258069465 -0.659013910281472 0.510871012510098 ATRNL1 other 1 1 1 -1.81510751206694 -0.659013910281472 5.9641357889783e-05 198.951110948958 88.2995284818281 2.25313899597892 0.0256266062418598 -287.403717756941 153.577956389425 -1.8713865226086 0.0631403028137257 HPS1 other 0.449815121204743 1 1 2.25313899597892 -1.8713865226086 0.0247948363599124 64.1826082805822 26.5948652372577 2.41334587364881 0.0169733967641022 -66.4753085513143 132.728898811551 -0.500835229904952 0.61719754830811 PHYH other 1 1 1 2.41334587364881 -0.500835229904952 0.257913764916602 24.5506110308765 43.090435481494 0.569746180481751 0.569702155986659 159.329506633991 96.5784554008602 1.64974171488532 0.101088320086929 RASSF4 other 1 1 1 0.569746180481751 1.64974171488532 1.33539707067842e-05 52.1218650316122 44.0484569400408 1.18328469718158 0.238496425677063 -259.556797127194 79.4945413523334 -3.26508956101519 0.00134515667347502 DNMBP other 0.108914985084532 1 1 1.18328469718158 -3.26508956101519 1.08891725404116e-07 272.002881465115 52.9433292962062 5.13762328665278 8.20614932933505e-07 -8.6460900504025 94.9198645531107 -0.0910883100298224 0.92753927755601 RAB11FIP2 other 0.00108031480773424 1 0.00901117257854282 5.13762328665278 -0.0910883100298224 0.71205571533459 -199.76448125372 249.812404321694 -0.799657974535461 0.425181982737259 -80.0428155789204 559.970203134494 -0.142941204962107 0.886529735228972 CXCL12 other 1 1 1 -0.799657974535461 -0.142941204962107 1.96815598396538e-07 180.807847252071 54.5308224944753 3.31569998362649 0.00113703109964389 -202.587123797966 98.5118768218911 -2.05647410579987 0.0414027500878123 ERLIN1 other 0.00191265398521756 1 1 3.31569998362649 -2.05647410579987 2.06863215031102e-08 1161.36286343823 245.878399971574 4.72332203061553 5.18454255106599e-06 -587.529007999236 441.697760572288 -1.33016071269639 0.18543187179565 EIF3A essential 0.00021629617763652 1 0.0539555343289438 4.72332203061553 -1.33016071269639 0.0430046086090683 15.5665684214198 6.162533591263 2.52600139064385 0.0125213335871934 17.8768126684049 24.4889030742671 0.729996464692198 0.466473280875933 CUBN other 1 1 1 2.52600139064385 0.729996464692198 1.50415802920056e-07 76.5101757467686 13.1021382424708 5.83951827792195 2.88921123382962e-08 70.4171568236056 51.6448147750806 1.36348938669411 0.174667936078404 TRDMT1 other 0.00147527819503991 1 0.000344654008083535 5.83951827792195 1.36348938669411 2.93358480886378e-14 219.81461347093 30.8839324964923 7.11744249201087 3.98891752764047e-11 -131.986843115574 67.4417952998942 -1.95704818545632 0.0521619247285324 DDX50 other 3.8764389664326e-10 1 5.25579773441909e-07 7.11744249201087 -1.95704818545632 7.78352300224293e-08 166.289177110658 30.9762444252067 5.36828076470565 2.81103210409808e-07 -30.567942614722 70.0892118316672 -0.436129067739224 0.663342199811777 MAPK8 other 0.000781310038965145 1 0.00318012061936615 5.36828076470565 -0.436129067739224 2.38329375509802e-09 259.240100972509 43.2890164688693 5.98858837920094 1.40600091850574e-08 15.0880758588326 78.7359912357152 0.191628702732183 0.848282255361748 SEC23IP other 2.63639955188943e-05 1 0.000169985511047344 5.98858837920094 0.191628702732183 6.66533758795804e-09 145.717393921435 25.9522206766317 5.61483334074159 8.7912696546615e-08 -12.2321689848685 47.0160242024185 -0.260170212015487 0.79507555663828 ATE1 other 7.18323431854238e-05 1 0.00102435874016116 5.61483334074159 -0.260170212015487 0.000469315589605751 99.1934510029079 32.3710591324079 3.06426337788872 0.00257159799598468 -48.4203322652937 58.6446346380539 -0.825656644706493 0.410259767519571 NSMCE4A other 1 1 1 3.06426337788872 -0.825656644706493 3.76375225582974e-05 192.974236899438 47.6618834769258 4.04881684948227 8.10800765415203e-05 -15.5050200665063 86.6594837680577 -0.178918906417734 0.85823503310674 PLEKHA1 other 0.290975686898197 1 0.748936667014023 4.04881684948227 -0.178918906417734 7.65862095174099e-05 165.330002082032 39.0394986900966 4.23494172900259 3.89325746784049e-05 31.6114333303591 85.7772151569776 0.368529489707823 0.712978094970743 PALD1 other 0.570337502276151 1 0.372078616201516 4.23494172900259 0.368529489707823 0.523841709799675 211.73249551167 220.591151313422 0.959841291234907 0.338629966197087 -77.3508078994607 505.305562631976 -0.15307729346292 0.8785364219622 UNC5B other 1 1 1 0.959841291234907 -0.15307729346292 0.451709547090751 -1.2867928145661 102.662125032809 -0.0125342507195801 0.990015921967191 -276.838525266375 241.35373883368 -1.14702397652579 0.253185923584872 CDH23 other 1 1 1 -0.0125342507195801 -1.14702397652579 0.13202195253988 -31.5724669964385 88.756428370593 -0.35572034134374 0.722543201437053 -407.853350080623 208.622626990107 -1.95498137457527 0.0524197423631977 VSIR other 1 1 1 -0.35572034134374 -1.95498137457527 0.11069879023451 1228.47808909494 1259.6692457349 0.975238613830121 0.331001667936981 -3691.66234918075 2888.28990124629 -1.27814813450264 0.203158457238901 SPOCK2 other 1 1 1 0.975238613830121 -1.27814813450264 9.87553534926049e-08 229.620565742191 59.821383893715 3.8384362045211 0.000182059703664335 -329.659210117701 130.185923336391 -2.53221855074059 0.0123630734498704 MICU1 other 0.000983109544018881 1 1 3.8384362045211 -2.53221855074059 3.51213466242494e-10 186.056945887241 41.1215571329845 4.52455983817794 1.22310648970005e-05 -268.389824520904 88.3164384007149 -3.03895661307296 0.00280150149673861 PPP3CB other 4.0589740293645e-06 1 0.12322797883728 4.52455983817794 -3.03895661307296 3.20968369647911e-07 132.49349633821 32.1888591044193 4.11612899694292 6.20675890807522e-05 -79.7906909065145 63.6557471543799 -1.25347190903287 0.211897427036404 CCSER2 other 0.00305497694230882 1 0.58089056620676 4.11612899694292 -1.25347190903287 4.30751718321006e-14 281.842172742897 46.8302660251117 6.01837650445474 1.25177487427618e-08 -173.42279401606 86.2550394716619 -2.01058158547404 0.0461265121324423 BMPR1A ts 5.67601539231589e-10 1 0.000151690079264788 6.01837650445474 -2.01058158547404 1.27269570565389e-06 95.7970660661292 27.1256872350366 3.53159959547103 0.000544304530612037 -69.7858059899396 48.8160103080387 -1.42956799520439 0.154853496791864 MINPP1 other 0.0115038964834055 1 1 3.53159959547103 -1.42956799520439 0.97919984793588 -104.970384180446 638.401278605091 -0.164426964196886 0.869605201910261 11.5543058569421 1140.75403686441 0.0101286565583422 0.991931417127819 ACTA2 other 1 1 1 -0.164426964196886 0.0101286565583422 0.738392216575703 -84.0682681063479 116.980866739269 -0.71864972836731 0.473424943692376 -136.452325144114 209.285129451048 -0.651992454036395 0.515359403079333 LIPA other 1 1 1 -0.71864972836731 -0.651992454036395 9.29831056824883e-15 167.514340195689 28.4513446801327 5.88774773491331 2.36882162393504e-08 -119.234922086663 52.3019192523414 -2.27974276644399 0.0239958789071342 TWNK other 1.24104551154417e-10 1 0.00028369007768246 5.88774773491331 -2.27974276644399 1.66840467215514e-15 652.164748313172 101.051089273882 6.45381215580554 1.34433165251902e-09 -344.887245681548 185.761550850506 -1.85661265263177 0.0652767296615716 LZTS2 other 2.2571846809587e-11 1 1.68955602088591e-05 6.45381215580554 -1.85661265263177 0.00819993818712132 -59.9187302628172 54.4115663052178 -1.10121311205613 0.272522119031944 -305.957419455038 100.024423424744 -3.05882712420966 0.00262133900729957 SFXN3 other 1 1 1 -1.10121311205613 -3.05882712420966 0.00263566348843392 156.714607587241 65.8751542550931 2.37896380447754 0.018578647656276 -81.3630668358515 115.030821597847 -0.707315358663618 0.480432617655078 KAZALD1 other 1 1 1 2.37896380447754 -0.707315358663618 9.81030959212265e-05 85.8387985225319 59.1721863258211 1.4506612625377 0.148881965672877 -262.710671211015 103.549860531128 -2.53704514775317 0.0121610405453829 FBXW4 other 0.720469136445488 1 1 1.4506612625377 -2.53704514775317 3.62807964376376e-05 25.9117770296631 45.5552366073353 0.568799087863607 0.570315725875638 -273.087409034209 79.8559926177739 -3.41974847575092 0.000801214549681013 NPM3 other 0.281139891595254 1 1 0.568799087863607 -3.41974847575092 1.92853744645298e-10 298.145856864154 70.1112614281959 4.25246744660982 3.60692024592143e-05 -261.54392134716 121.628938124912 -2.15034288204142 0.0330489958906197 TNKS2 other 2.25523168988211e-06 1 0.346156136001079 4.25246744660982 -2.15034288204142 2.26943583591659e-08 533.342179737123 118.179413047801 4.51298721141388 1.27255177851633e-05 -199.314063266461 206.876889963753 -0.963442863537744 0.336855570148164 GBF1 essential 0.000236588685894304 1 0.127916904776461 4.51298721141388 -0.963442863537744 0.000617000811518759 191.858369510818 56.9272906119003 3.37023539059332 0.000953587052599157 -153.471182159942 243.715453831548 -0.629714610818315 0.529832987121964 ARHGAP21 other 1 1 1 3.37023539059332 -0.629714610818315 0.0101038116221845 4.20378889002986 15.5818736325076 0.269787125038655 0.787676063674779 -62.3903172810349 27.0314169979588 -2.30806684258343 0.0222922803128997 CPEB3 other 1 1 1 0.269787125038655 -2.30806684258343 1.16690478520123e-05 73.49646107179 36.2094308070261 2.02976018771134 0.0441369020606316 -157.065283778125 63.839149816376 -2.46032856374028 0.0150084129782186 FBXL15 other 0.0957678757214645 1 1 2.02976018771134 -2.46032856374028 1.37328307985223e-07 199.613874316079 67.9029989936499 2.93969157878794 0.0037987722278272 -287.782018277931 119.658477273214 -2.40502825070089 0.0173735844173079 CUEDC2 other 0.00135172253549855 1 1 2.93969157878794 -2.40502825070089 2.62696100035919e-09 160.847160059676 39.5464087352953 4.06730131012174 7.59133460311899e-05 -133.896220840115 70.9890778291346 -1.88615241857899 0.0611694961056187 SUFU ts 2.90069033659662e-05 1 0.703337150978974 4.06730131012174 -1.88615241857899 2.75827507304111e-06 52.7308437365477 10.8717327101599 4.85027043456184 2.99080702550755e-06 -3.38848232649352 45.5241238487117 -0.0744326752504741 0.940762706575206 ANKRD26 other 0.0241018075882333 1 0.0316876004352525 4.85027043456184 -0.0744326752504741 6.31970067148829e-05 71.2811913863103 17.8796736909569 3.98671657091609 0.000102916700528215 -36.1862342410789 74.873659690747 -0.483297255544073 0.62956667961942 ACBD5 other 0.47511509648249 1 0.940658642827881 3.98671657091609 -0.483297255544073 0.00062261119922788 142.479781563716 48.7026452085211 2.92550396295082 0.0039594158441387 -97.3960803549047 90.1017368321699 -1.08095674710824 0.281406219918479 LHPP other 1 1 1 2.92550396295082 -1.08095674710824 1.05015393506013e-13 518.456715568483 67.3382818372585 7.69928637058897 1.95063153899502e-12 -124.004679398001 247.531164226304 -0.5009659280099 0.617154733330435 LARP4B other 1.36898066974438e-09 1 2.63686371441347e-08 7.69928637058897 -0.5009659280099 3.19407032458715e-17 420.374962267377 44.7021596636369 9.40390722574711 8.88922179660346e-17 131.51639323395 162.381490217631 0.809922319703344 0.419276418163674 GTPBP4 essential 4.41676044483911e-13 1 1.25533590211634e-12 9.40390722574711 0.809922319703344 0.000136205441230796 96.4093462109954 24.9933313305559 3.85740279820678 0.000167670292101943 -1.92693907875193 46.3124643647326 -0.0416073535533841 0.966865258646995 EDRF1 other 0.980815382302963 1 1 3.85740279820678 -0.0416073535533841 3.64344935939021e-09 338.029545744003 59.4892409888081 5.68219631189441 6.40783148595197e-08 -56.502808320951 110.233138469656 -0.512575520441201 0.608977948273055 BCCIP other 3.98739097891664e-05 1 0.000752599808025058 5.68219631189441 -0.512575520441201 0.0310070007590688 20.9922198139195 43.7669507459973 0.479636334177092 0.632162089392336 -140.499574077403 75.8436052948522 -1.85249070809849 0.0658571718263187 NEURL1 other 1 1 1 0.479636334177092 -1.85249070809849 0.0301204701628422 90.8887584829586 141.063225356969 0.644312210024685 0.520325345402556 -424.663618165125 244.448000220147 -1.73723498569298 0.0843321381058586 SH3PXD2A other 1 1 1 0.644312210024685 -1.73723498569298 4.01064617062119e-08 564.311966823425 102.516941556582 5.50457278821538 1.52577599424802e-07 -273.509664066601 445.418987566728 -0.614050302526958 0.540094043776161 PITRM1 other 0.000410890700180141 1 0.00175632074697889 5.50457278821538 -0.614050302526958 1.83880727979322e-06 16.4810290110127 17.9818896007701 0.91653487908784 0.360810236212091 -115.515675501757 30.7528565275754 -3.75625839499419 0.000243624624658017 STN1 other 0.0163837728629576 1 1 0.91653487908784 -3.75625839499419 0.206084418826917 -26.8023582257159 21.3868510241454 -1.25321667016133 0.212001951381963 -151.912876661052 94.4280481660589 -1.60876857683113 0.109688834235444 MAP3K8 other 1 1 1 -1.25321667016133 -1.60876857683113 0.340717084651135 19.5087950024659 22.033564075493 0.885412588522829 0.377351315192402 61.910378650885 42.8727587758647 1.44404933152418 0.150810542422832 EBF3 other 1 1 1 0.885412588522829 1.44404933152418 0.000299486965683944 249.958819661352 72.3033666090486 3.45708410803198 0.000710660768321277 -78.4697791659814 140.687397857729 -0.557759830381784 0.577839855689562 GLRX3 essential 1 1 1 3.45708410803198 -0.557759830381784 0.106548637861367 60.7715039577838 39.9174800219899 1.52242836783048 0.129939322496157 -29.1824293950943 68.0074812970976 -0.429106163594089 0.668441792074685 SORCS1 other 1 1 1 1.52242836783048 -0.429106163594089 4.73972743038318e-12 413.952080508435 54.0633115905908 7.6568021515811 1.91530267292848e-12 264.569840698822 206.705417308933 1.27993665644189 0.20247976609036 FAM208B other 5.88958530499414e-08 1 2.5894892137993e-08 7.6568021515811 1.27993665644189 2.5558462705457e-06 274.094560449557 66.7336067267313 4.10729426886744 6.48043660281608e-05 -80.5319328495475 112.850987522608 -0.713613009663864 0.476546591433172 XPNPEP1 other 0.0224096601001447 1 0.605467191801107 4.10729426886744 -0.713613009663864 3.11504255603327e-08 333.216398534935 73.5559809014066 4.53010611035931 1.18502013996428e-05 -197.414743381706 131.51826624231 -1.50104429614353 0.135418538832341 SMC3 essential 0.000321534692633754 1 0.119532981518197 4.53010611035931 -1.50104429614353 2.10707391381249e-09 142.710189447255 32.7137121464788 4.36239668577679 2.36292927945408e-05 -144.771241488187 58.411009680244 -2.4784923643796 0.0142870034015026 SHOC2 other 2.33969487389739e-05 1 0.231165371408993 4.36239668577679 -2.4784923643796 4.20648211341096e-05 176.447677146879 53.5193052518217 3.29689775150571 0.00121378976839381 -218.936588629925 115.773295609251 -1.89108021394556 0.0604915718562666 TFAM essential 0.322847502204291 1 1 3.29689775150571 -1.89108021394556 7.12704490446063e-06 2184.04746497171 473.637210374214 4.61122440790943 8.3219787783053e-06 -355.559321964216 1090.56992975656 -0.326030740682153 0.744840854284791 CCDC6 other 0.0596676199401444 1 0.0850755890506151 4.61122440790943 -0.326030740682153 3.57344255950817e-05 270.431027580791 103.848024824761 2.60410371826648 0.0101376591073075 -367.939806384245 205.412610384446 -1.79122306900057 0.0752738495726139 UBE2S other 0.277190975217326 1 1 2.60410371826648 -1.79122306900057 1.19649363519303e-11 2095.31046640475 311.866562057464 6.71861212879459 3.51366405263819e-10 -581.4874248682 775.447265819905 -0.749873589731952 0.454497591625524 ZMIZ1 other 1.4671404954737e-07 1 4.49573315535056e-06 6.71861212879459 -0.749873589731952 0.587288521586439 -16.9678138373752 17.1578084917737 -0.988926636260709 0.32422068120871 -3.85477888730394 36.9070920223795 -0.104445478526634 0.916949143146978 DNAJC12 other 1 1 1 -0.988926636260709 -0.104445478526634 0.000179249925612775 288.504011231448 159.571970171003 1.80798677187652 0.0725726244606021 -1065.48309934483 390.766485751526 -2.72664913239856 0.00714544946337494 PPIF other 1 1 1 1.80798677187652 -2.72664913239856 0.0164429480036527 41.8102189781021 19.7028692643826 2.12203707069627 0.0354038849693637 -42.5973722627737 42.4670180854556 -1.00306953921407 0.317370779527544 PBLD other 1 1 1 2.12203707069627 -1.00306953921407 8.29536664600148e-07 767.983832989439 177.593414977681 4.3243936329844 2.72699472988266e-05 -451.344489622527 419.687374745531 -1.0754302292181 0.283853306897379 TSPAN14 other 0.00762012380101696 1 0.265282047322985 4.3243936329844 -1.0754302292181 0.0400212765437278 6.88557364560649 3.44791955705305 1.99702270649598 0.0475507672286288 -0.94886169412728 6.09251294124738 -0.155742253365327 0.876436256322917 LGI1 other 1 1 1 1.99702270649598 -0.155742253365327 0.000972977546728416 -1.80597086956946 10.7164275632431 -0.168523592298973 0.866386923929013 -60.5320212735152 18.7352373537476 -3.23091830279946 0.00150156019369735 TBC1D12 other 1 1 1 -0.168523592298973 -3.23091830279946 9.17970487724107e-05 -244.51814392185 170.554739457203 -1.43366372989715 0.15366952209441 -3116.30286748915 708.598564687309 -4.3978396553263 2.01509310616039e-05 KRT23 other 0.676452452403895 0.291704878047778 1 -1.43366372989715 -4.3978396553263 1.42157724278251e-09 446.350945433404 67.3554631618566 6.62679646877066 6.97436853552491e-10 -235.18773012929 319.282465533346 -0.736613361264361 0.462598919316233 NUFIP2 other 1.59174003874358e-05 1 8.84210442933848e-06 6.62679646877066 -0.736613361264361 1.73473722265371e-11 580.117524048516 81.8610698090175 7.08661058793801 6.45166634756182e-11 -616.935173567548 328.815939191528 -1.87623256671933 0.0627353536565413 GIT1 other 2.11481814813713e-07 1 8.45361841521026e-07 7.08661058793801 -1.87623256671933 0.0112957697276209 5459.7507731855 2885.33094004872 1.8922442127534 0.0603599699331627 -23103.1448568101 11050.4610349594 -2.09069511070358 0.0382196678118648 RPL19 essential 1 1 1 1.8922442127534 -2.09069511070358 2.05392959955581e-15 253.811697936576 27.8128128430542 9.12571120975135 4.08010177254744e-16 60.2113351796231 109.437765649704 0.55018790654363 0.582998097336328 FBXL20 other 2.77424271012003e-11 1 5.73743911255621e-12 9.12571120975135 0.55018790654363 0.567447605012796 2.04907307440318 9.87503852695112 0.207500261270963 0.83588981525901 -39.4822781422734 38.7268987531987 -1.01950528995076 0.309541621106944 RUNDC3A other 1 1 1 0.207500261270963 -1.01950528995076 2.02409174351448e-07 510.196503262506 89.6952820594214 5.68810857771216 6.22705459985111e-08 667.536724109085 351.710645042242 1.89797133956213 0.0595588679401246 UBTF essential 0.00196519067377821 1 0.000731803456574503 5.68810857771216 1.89797133956213 4.12115283602932e-141 1569.36758043411 15.2883876234847 102.650954376862 2.71389861634214e-142 -292.983780631908 521.930926055788 -0.561345890817344 0.575388433941799 PSMD3 essential 6.02842236854368e-137 1 3.96989089598529e-138 102.650954376862 -0.561345890817344 2.73797875566052e-19 630.201814058955 69.4925190968301 9.06862813795597 6.23874665720871e-16 -1590.57272432783 367.317600940388 -4.33023824683523 2.71145386260362e-05 RAPGEFL1 other 3.85233610921435e-15 0.391886426762101 8.7641913040468e-12 9.06862813795597 -4.33023824683523 0.0196142052915456 36.5940427642456 15.5228420896527 2.3574318770297 0.0196509470232557 101.65575746721 61.9699774930241 1.64040333044584 0.102949134833107 RGS9 other 1 1 1 2.3574318770297 1.64040333044584 6.74670927150821e-08 335.597453419777 58.2148791417122 5.76480546498832 4.20989123616939e-08 449.189255884587 224.169807764967 2.00379016408643 0.0468125939303666 RNF43 other 0.000681012833866039 1 0.000498661616924264 5.76480546498832 2.00379016408643 2.08177496119483e-10 96.119692793885 13.3844816460727 7.1814281147069 2.65160055570708e-11 18.0549075809357 51.5481229239932 0.350253443904394 0.726620963968666 RAD51C essential 2.43068044469108e-06 1 3.50753721508932e-07 7.1814281147069 0.350253443904394 0.280640839538899 5.96707455995296 6.36188894378758 0.937940698537317 0.349724756618274 32.2819608275458 24.5017656996363 1.31753610018502 0.189590719322705 SEPT4 other 1 1 1 0.937940698537317 1.31753610018502 5.22209191274335e-11 395.239980891485 53.4691161795184 7.39193031664292 8.27180576241065e-12 203.786190423694 205.927479774148 0.989601730896708 0.323901261479535 MTMR4 other 6.25293285631889e-07 1 1.1042033512242e-07 7.39193031664292 0.989601730896708 5.52636773662294e-09 264.800310657313 40.8138714377398 6.48799786271825 1.09417555752676e-09 173.636280651646 157.0474677569 1.1056292924151 0.270589201292465 TRIM37 other 5.98014753060728e-05 1 1.37855178492796e-05 6.48799786271825 1.1056292924151 0.0957164521242533 6.65712082567173 3.06996403218844 2.1684686712522 0.0316285522268123 10.3967020582477 17.4854533786851 0.594591506041322 0.552972469788156 P2RX1 other 1 1 1 2.1684686712522 0.594591506041322 1.9261450407531e-14 563.06732671832 63.963240809371 8.80298308205527 2.38367442948626e-15 -117.902499836918 248.029158253952 -0.475357416309094 0.635197150281671 DHX40 other 2.55637969808752e-10 1 3.33380705707949e-11 8.80298308205527 -0.475357416309094 2.27309560535609e-09 59.8337452762742 9.05126796376072 6.61053738722964 5.75015730428636e-10 48.358043100807 36.2088180469774 1.33553221864539 0.18364754710219 TUBD1 other 2.51631683512919e-05 1 7.31305005959139e-06 6.61053738722964 1.33553221864539 1.77808105060314e-08 1254.02689646168 199.529499776528 6.28491976307355 3.1328042783002e-09 -331.514003133558 829.24989153819 -0.399775757002062 0.689868526462207 KPNB1 essential 0.000186842421154457 1 3.88655698765923e-05 6.28491976307355 -0.399775757002062 2.04180170954883e-09 129.173742759347 19.4241825917402 6.65015076692473 4.66413486665279e-10 130.268545945236 80.4281656259432 1.61968813948948 0.1073190898058 GOSR2 essential 2.26885005965065e-05 1 5.94677195498231e-06 6.65015076692473 1.61968813948948 2.44804377257749e-07 271.009577273114 49.1934643949156 5.50905655063246 1.49370968733389e-07 -306.596070426129 202.308693074246 -1.51548638749601 0.131712533958956 PNPO other 0.00235526291359681 1 0.00171970796302751 5.50905655063246 -1.51548638749601 4.43506803676359e-09 166.313151533722 25.2986117218634 6.57400308610578 6.97061030590753e-10 69.9960371770004 101.204917625428 0.691626838095598 0.490199735761183 RPS6KB1 other 4.82978909203555e-05 1 8.83803680686016e-06 6.57400308610578 0.691626838095598 8.85043257884148e-08 40.5640326975477 8.66141979770458 4.68330061871586 6.12555696145106e-06 -57.4695731153497 25.8320287042318 -2.22474099008473 0.0275430789946566 TRIM16L other 0.000884600736255206 1 0.0633592376267336 4.68330061871586 -2.22474099008473 0.000245779531908794 395.84524929445 94.5295963577765 4.18752712955899 4.74446490266856e-05 143.269520225761 394.56182475963 0.363110446158956 0.717023555038803 CDK5RAP3 other 1 1 0.45005994066714 4.18752712955899 0.363110446158956 3.81644779025242e-09 479.653519221607 76.0260382646174 6.30906897387073 2.87577629817185e-09 763.778209877482 328.65274684145 2.3239672183417 0.0214430587519048 CBX1 other 4.17175907952492e-05 1 3.5728644728487e-05 6.30906897387073 2.3239672183417 2.70356810847612e-11 225.209530626182 29.9051481446759 7.53079468246262 3.89170911990615e-12 78.769824280311 138.797116272374 0.567517729444276 0.571183557222433 RECQL5 other 3.27293955212119e-07 1 5.23084622806585e-08 7.53079468246262 0.567517729444276 3.51563851211445e-10 90.3913286909055 13.4553876408406 6.71785392615109 3.30786823508797e-10 -37.2547503236871 45.3238720519597 -0.821967511535154 0.412357987185069 PIGL other 4.06267186459946e-06 1 4.23605606185365e-06 6.71785392615109 -0.821967511535154 0.000578749212162454 90.9952774418003 23.0222651417798 3.95249020378391 0.000117840731544054 -28.3035279888018 105.780275257693 -0.267569052168289 0.789391410620794 GALK1 other 1 1 1 3.95249020378391 -0.267569052168289 6.72627186512062e-14 133.995039514136 15.6544045315029 8.55957435139004 1.00904204620978e-14 58.2741092815785 65.1703329944866 0.894181548627478 0.372602235620231 INTS2 essential 8.81881504235964e-10 1 1.40347658207318e-10 8.55957435139004 0.894181548627478 3.7246410751654e-18 358.785861850654 37.6651356629921 9.52567554942274 4.51486123699392e-17 -385.068658158672 187.909603400006 -2.04922287733731 0.0422063581108472 CAMTA2 other 5.20108879736097e-14 1 6.3844652752331e-13 9.52567554942274 -2.04922287733731 1.84996183737533e-12 460.453349438698 58.7002958478158 7.84414018342348 6.44651173611684e-13 421.599580347304 245.560955407958 1.71688361306009 0.0879851434986264 MED13 other 2.32965694180675e-08 1 8.78079363576475e-09 7.84414018342348 1.71688361306009 0.000588016528738883 -25.7798654788597 65.6857991797585 -0.392472433932172 0.695251846605539 -1058.74976686971 268.588250189483 -3.94190649115433 0.000122348478121689 HOXB6 other 1 1 1 -0.392472433932172 -3.94190649115433 9.35348459315573e-06 545.225920501036 113.455997794021 4.80561566688517 3.77064998410327e-06 -255.594423960803 565.030043815659 -0.452355457481108 0.651679766701814 ENO3 other 0.0775216803080747 1 0.039689861732671 4.80561566688517 -0.452355457481108 0.000591199050393872 3205.85418455478 837.68287114649 3.82704994333608 0.000191291584993903 -994.397696853354 4171.80227216221 -0.238361655701857 0.811932554853019 PFN1 essential 1 1 1 3.82704994333608 -0.238361655701857 2.30715886815128e-14 1017.33380473761 116.056148471772 8.76587598445989 4.1843444683896e-15 285.843047628672 577.97923363323 0.494555913076386 0.621651931335103 RNF167 other 3.05790836384771e-10 1 5.84008957453137e-11 8.76587598445989 0.494555913076386 8.76390768628319e-12 498.752397645346 64.7864474138048 7.69840634198861 1.76182181483158e-12 102.490905483166 323.25111537078 0.317062805384619 0.751639774155898 SLC25A11 other 1.07997634418068e-07 1 2.38374491546712e-08 7.69840634198861 0.317062805384619 0.526995496034607 68.9842022116903 66.2616275364128 1.04108825539761 0.299476912307344 137.65560821485 206.593905749413 0.666310110724267 0.506216352635862 RASD1 other 1 1 1 1.04108825539761 0.666310110724267 2.30160564130581e-08 78.0453963564747 13.864287970435 5.62923941877888 8.65134067223358e-08 -116.010569505991 69.1829730644986 -1.67686591609521 0.0956514899956088 CHRNE other 0.000239758259654826 1 0.0010082272419421 5.62923941877888 -1.67686591609521 0.000973013694726703 541.721970723324 145.468324967675 3.72398576008695 0.000278803736358076 4.85447576247724 448.728745743492 0.0108182856759799 0.991383093355285 RAI1 other 1 1 1 3.72398576008695 0.0108182856759799 8.56062194526586e-23 466.37102579484 40.0950324966584 11.6316410476462 6.00605389654606e-23 -136.573049026557 213.666531246019 -0.63918784205517 0.523632219261453 NUP88 essential 1.22485378792864e-18 1 8.65592487570218e-19 11.6316410476462 -0.63918784205517 6.67588527588706e-19 1319.21565686862 130.18318717008 10.1335332583701 6.98662703575842e-19 -659.660413371863 693.746539088113 -0.950866600702536 0.343133597857736 C1QBP essential 9.36893739617991e-15 1 9.96782079191654e-15 10.1335332583701 -0.950866600702536 4.28547375060276e-18 282.595908158492 27.9217510655115 10.120995187424 1.34345789412445e-18 -36.1571598229391 115.391247004422 -0.313344042651289 0.754463450301381 BLMH other 5.97995007159109e-14 1 1.91429315333792e-14 10.120995187424 -0.313344042651289 0.00312821972662301 623.96906696221 180.681436344733 3.45342100209842 0.0007220873345441 248.865392798123 711.3890536757 0.349830225124005 0.726963432048148 CPD other 1 1 1 3.45342100209842 0.349830225124005 8.47111249956376e-18 349.322224091355 35.6132236898456 9.80877853500685 8.2906530773787e-18 -135.925715190436 140.218375565281 -0.969385892843646 0.333934216326793 GOSR1 other 1.17824703756432e-13 1 1.17669239127236e-13 9.80877853500685 -0.969385892843646 1.44172230782491e-07 513.016200847593 87.0517293938371 5.89323387852089 2.28211354738976e-08 212.228340754251 352.245906701218 0.602500516590153 0.547721452707339 CCDC47 other 0.0014162038229764 1 0.000273556950925611 5.89323387852089 0.602500516590153 2.78813395405705e-05 69.0092378752886 14.5708776878793 4.7361071414863 4.86070629392238e-06 56.5808314087773 73.4991301084479 0.769816341027334 0.442572968369008 MED31 other 0.219704955579696 1 0.0507311915896679 4.7361071414863 0.769816341027334 5.2152947239641e-15 191.522179155901 26.3492676778088 7.26859590550213 1.98392254903481e-11 -302.916302259325 81.2629891564015 -3.72760472392078 0.000275174550914782 DRG2 other 6.99214563641867e-11 1 2.63008612325545e-07 7.26859590550213 -3.72760472392078 3.05295536550017e-14 476.076115352424 54.5156337398361 8.73283648548218 3.88951744634053e-15 189.333439013874 227.61753143017 0.831805168188279 0.406806871362728 FTSJ3 essential 4.03295403782573e-10 1 5.42937740334674e-11 8.73283648548218 0.831805168188279 1.09130602474378e-56 220.672998156781 9.47187310770901 23.2977147864427 1.15809776811283e-52 -51.8284277463343 60.0367903243247 -0.863277791273518 0.389310039271047 AKAP10 other 1.59330679612592e-52 1 1.69001207300705e-48 23.2977147864427 -0.863277791273518 0.0242174355217452 8.1648038263051 12.1630268772489 0.671280587365753 0.503034568081478 -170.261025490545 77.0944760381341 -2.20847243849646 0.0286698499779352 ALDH3A1 other 1 1 1 0.671280587365753 -2.20847243849646 1.93949183758119e-08 726.816247010107 116.397733460464 6.24424742133812 4.05645490356981e-09 -432.28764692266 486.050438532624 -0.889388451593063 0.37519976232201 SMARCD2 other 0.000203239349660133 1 5.01499519728335e-05 6.24424742133812 -0.889388451593063 0.025047090198036 47.4225864190626 18.3385125893395 2.58595598678107 0.0106435814925411 -62.691324532945 73.1912392854595 -0.85654137223223 0.393037939413433 ICAM2 other 1 1 1 2.58595598678107 -0.85654137223223 0.0202074287843609 1356.56090378765 494.664840987327 2.74238391610776 0.00680382336254946 -1234.42322829151 1941.63749535737 -0.635764003962182 0.525850040555783 SYNGR2 other 1 1 1 2.74238391610776 -0.635764003962182 0.00196017217971077 83.7602821419757 25.4155173689159 3.29563553344845 0.00121566138761572 -18.0674097227936 71.2924804960761 -0.253426582959027 0.800272265280306 B9D1 other 1 1 1 3.29563553344845 -0.253426582959027 2.33759891852866e-14 201.765360864532 23.9068364563215 8.43965119488575 2.25550188014911e-14 -117.342358162871 93.1748425394133 -1.25937812144125 0.209811648697259 UTP6 other 3.09755232694233e-10 1 3.12477230475857e-10 8.43965119488575 -1.25937812144125 1.07721858430107e-16 150.654819370913 16.0254258427206 9.40098695969106 7.85041670266257e-17 -66.9678838368111 62.416686721308 -1.07291635225407 0.285009075986717 C17orf75 other 1.48106783155554e-12 1 1.10894986341811e-12 9.40098695969106 -1.07291635225407 0.0254730468138749 95.7947089947091 37.9073955640506 2.52707176447532 0.0124911071844343 169.183862433862 153.349970894384 1.10325330645405 0.271605356022533 CYTH1 other 1 1 1 2.52707176447532 1.10325330645405 6.58019777232013e-09 564.945574491478 86.3699648922306 6.54099576393712 8.92063018223338e-10 362.009345794392 336.174048404367 1.07685095715345 0.283264273042337 PSMD11 essential 7.0934531985611e-05 1 1.12801368654341e-05 6.54099576393712 1.07685095715345 0.0281565917493966 5086.1681871345 1882.74323817102 2.70146671304762 0.00765722283851754 -209.557894736785 7657.9566114641 -0.0273647273507757 0.97820336385916 LGALS3BP other 1 1 1 2.70146671304762 -0.0273647273507757 0.00473205815136979 -6.57031905961375 7.18522463210078 -0.914420828300917 0.361953618142361 -91.677671824397 27.7361533942895 -3.3053491780613 0.00118504819545759 ASIC2 other 1 1 1 -0.914420828300917 -3.3053491780613 0.638269540508415 1.78551414962175 3.87872650837918 0.460335150149028 0.645937890288083 13.31669535284 14.9603136109477 0.890134772515401 0.374809524911634 CCL7 other 1 1 1 0.460335150149028 0.890134772515401 0.860557555854586 -67.7060801344916 130.467652852847 -0.518949169805765 0.604555919510807 48.4440619621356 503.215939186819 0.0962689338505845 0.923434632922131 CCL2 other 1 1 1 -0.518949169805765 0.0962689338505845 0.127010818458189 13.5855281591482 17.830965946196 0.761906460936656 0.447304230321508 136.988812392427 68.7743366192351 1.9918594511621 0.0481896847622644 CCL8 other 1 1 1 0.761906460936656 1.9918594511621 1.53178635519821e-07 42.5440568180692 7.59359561550645 5.60262344378628 9.65031720914171e-08 -29.2007082419928 29.3093937946357 -0.996291784354037 0.32069178806549 PEX12 other 0.00150099744945873 1 0.00112242839459527 5.60262344378628 -0.996291784354037 0.00796761486173235 70.6050024274901 23.0361672136911 3.06496309792053 0.00256855647202455 101.54721018467 91.9592339973366 1.10426333246328 0.271190224290984 DHX58 other 1 1 1 3.06496309792053 1.10426333246328 0.000118690604003326 394.204898135329 102.046838989062 3.86298000056211 0.000164216973224724 -655.518116267779 407.365906760149 -1.60916293040139 0.109615564470768 KAT2A other 0.862999381708185 1 1 3.86298000056211 -1.60916293040139 4.45862816222248e-08 951.309113878364 155.29844710411 6.12568336398508 7.13715579314052e-09 84.1099440534188 618.709481766572 0.135944165286208 0.89204181764072 RAB5C other 0.000455225935362915 1 8.74515699333508e-05 6.12568336398508 0.135944165286208 4.56644333945259e-06 166.461147135743 35.8497099908371 4.64330526462526 7.23178408447071e-06 -245.745691971484 142.85872941908 -1.72020073936527 0.0873789529360063 NAGLU other 0.0389928596755856 1 0.0742631907634298 4.64330526462526 -1.72020073936527 3.80700801792917e-09 117.820657041522 26.8776519346669 4.38359188994319 2.13605527359057e-05 -477.55733887436 107.105669924141 -4.45874937538411 1.56826401160649e-05 HSD17B1 other 4.16220186600197e-05 0.227288503202129 0.210102396710368 4.38359188994319 -4.45874937538411 1.0113674247583e-09 280.404685988607 54.2704957482735 5.16679794651641 7.18466386843689e-07 -854.01144627951 216.264345500243 -3.94892391671909 0.000118541300643529 MLX other 1.14142927558222e-05 1 0.00791749958301746 5.16679794651641 -3.94892391671909 0.214591108889343 28.4571551788794 17.6112281293651 1.6158529643614 0.108186271524516 -35.9576989424738 69.3215343610018 -0.51870893040565 0.604713143122319 CNTNAP1 other 1 1 1 1.6158529643614 -0.51870893040565 0.25779977924476 -9.77800270346156 17.4735980257579 -0.559587252095863 0.576563563767057 110.11127291249 71.3970536196994 1.5422383323968 0.125041769520978 ABI3 other 1 1 1 -0.559587252095863 1.5422383323968 2.70321602060658e-07 166.96026890453 30.4689448103778 5.47968661020592 1.68909603273126e-07 -146.825726403176 121.388368043148 -1.209553508051 0.228291868804581 EZH1 other 0.00258995126934316 1 0.00193857551676567 5.47968661020592 -1.209553508051 0.0163396906693311 19.3333141309984 6.70323070046651 2.88417853940979 0.00447219393401207 16.3129020488891 27.5583182602552 0.591941129891649 0.55473608332907 DLX4 other 1 1 1 2.88417853940979 0.591941129891649 0.000578016927061516 407.19567477646 102.969565029357 3.95452456908378 0.000115759377596547 162.669629860675 421.545231103504 0.385888910271491 0.700101340876317 PPP1R9B other 1 1 1 3.95452456908378 0.385888910271491 0.886842647669463 -2898.49352351983 13623.754771538 -0.212752913725018 0.831795681923164 23514.3145878131 55525.8179459784 0.423484343998145 0.672521493994086 COL1A1 other 1 1 1 -0.212752913725018 0.423484343998145 7.71471292606326e-13 84.7715384755288 12.7084011319637 6.67051170286987 4.25182929365469e-10 -201.662122837968 50.4186170666554 -3.99975514146615 9.79117891645104e-05 PTGES3L-AARSD1 other 9.82622985392677e-09 1 5.42703491042084e-06 6.67051170286987 -3.99975514146615 6.34272009446635e-10 263.023181162777 40.9652764534528 6.42063727951744 1.51351259617391e-09 -369.395599950413 166.739210377379 -2.21540931562747 0.0281620691501684 MRPL27 essential 7.23133517970108e-06 1 1.89885290315978e-05 6.42063727951744 -2.21540931562747 4.7667130860151e-09 1279.45147313692 195.05819535926 6.55933205359772 7.52956649135753e-10 56.886915077989 774.020821341518 0.0734953292075447 0.941506112800485 VAT1 other 5.18189379580701e-05 1 9.53920778790085e-06 6.55933205359772 0.0734953292075447 8.34787787403509e-10 968.44118587339 151.853858597835 6.37745523765834 1.89449090574448e-09 -1352.55048247875 618.084257386403 -2.18829466422275 0.0301164500562322 LRRC59 other 9.46231957021877e-06 1 2.37019757217691e-05 6.37745523765834 -2.18829466422275 2.94087812781989e-06 85.1187897169268 16.3022209492587 5.22130021313431 5.59745107693171e-07 77.9460932986709 64.6897118349511 1.20492256168248 0.230057906598191 RND2 other 0.0256062258589278 1 0.00621484993071728 5.22130021313431 1.20492256168248 3.51411447016725e-05 63.8345641924313 13.6509556174329 4.67619747520911 6.31426778967031e-06 64.5947970125589 73.5084763821428 0.878739435119767 0.380902769324396 ALOX12 other 0.273046694331995 1 0.0652390148028736 4.67619747520911 0.878739435119767 1.0004723602156e-08 389.089708340072 60.5626978610349 6.42457687788057 1.50247010585498e-09 273.227092206231 239.835468991468 1.13922721003352 0.256343595925673 HDAC5 other 0.000106650353598983 1 1.88544973583742e-05 6.42457687788057 1.13922721003352 1.03673004304191e-10 -3.36964411462016 35.7527598609902 -0.094248503548303 0.925031931468616 -1045.63231948432 143.38908974136 -7.29227252485104 1.409777799536e-11 ABCC3 other 1.22676265993149e-06 2.06236394294121e-07 1 -0.094248503548303 -7.29227252485104 2.85609296809319e-05 704.318376663139 148.958619132624 4.7282821280456 5.00397268316069e-06 243.81493208261 588.175003177548 0.414527871408046 0.679053389502887 LUC7L3 essential 0.224688833799891 1 0.0521514033039007 4.7282821280456 0.414527871408046 1.26203193734344e-05 60.9313956780221 12.948603703542 4.70563445086785 5.54130780488245e-06 105.856699485179 55.1982942370321 1.91775309270627 0.0569694465578983 MPP2 other 0.1031837311972 1 0.0575353989380944 4.70563445086785 1.91775309270627 3.34466562136934e-11 211.391507219968 28.2350571993889 7.48684536840758 5.09087542317908e-12 110.586322096139 113.011267841458 0.978542442787908 0.329340821043701 SMURF2 other 4.03366673937142e-07 1 6.83042755527938e-08 7.48684536840758 0.978542442787908 7.42459070882276e-05 238.223742568651 55.4290908604287 4.29781075010778 3.02569059359337e-05 -210.856657544588 236.287350872296 -0.892373869215489 0.373567014234138 DUSP3 other 0.554097204599443 1 0.293128904707326 4.29781075010778 -0.892373869215489 8.84237756368274e-17 913.082365536765 94.0480101844098 9.70868350905446 9.55870628269763e-18 202.507875444583 370.52937263899 0.546536632176494 0.585472999296999 EFTUD2 essential 1.21724169541657e-12 1 1.35609366032631e-13 9.70868350905446 0.546536632176494 0.266989325012182 4.86711181030618 4.40505219676863 1.10489310748156 0.270885612240877 -20.0752283259419 17.120987316535 -1.17255085555456 0.242740808433096 HLF other 1 1 1 1.10489310748156 -1.17255085555456 0.289050840778508 -2.42632549062126 4.15849952722487 -0.583461769019473 0.560430511995726 -24.8378781307601 16.7380682183575 -1.48391545587795 0.139862007461236 SLC16A6 other 1 1 1 -0.583461769019473 -1.48391545587795 3.04738073474091e-09 914.453024167213 138.554671002515 6.59994367241948 5.90650343333334e-10 622.414539516656 562.114615310985 1.10727336127404 0.269858631731083 PRKAR1A other 3.35364249858238e-05 1 7.51011911548334e-06 6.59994367241948 1.10727336127404 4.7028787751783e-10 232.717989808822 34.1827464347237 6.80805418175587 2.47921446369989e-10 52.0664429782291 173.664727900584 0.299810120383426 0.764754329144993 EFNB3 other 5.39890483390468e-06 1 3.19000525044265e-06 6.80805418175587 0.299810120383426 0.103119763485947 270.302273024168 140.53444560266 1.92338804814022 0.0562295192633152 -522.218445460485 570.146536787979 -0.91593724027948 0.361095656426969 FAM20A other 1 1 1 1.92338804814022 -0.91593724027948 7.5235815863617e-11 3796.70815986678 578.056204306484 6.56806056501345 8.95306721454208e-10 -4877.85928393008 2451.63835773583 -1.98963247109371 0.0485521392501446 YWHAE other 8.95155737145315e-07 1 1.13184675726241e-05 6.56806056501345 -1.98963247109371 0.0939512549616886 175.755365570655 83.896107673544 2.09491680179674 0.0377736553373125 226.807515714094 326.076543755617 0.695565259315549 0.487722916735454 MMD other 1 1 1 2.09491680179674 0.695565259315549 3.10783503768808e-06 106.472462871287 22.8067314345256 4.66846655238398 6.6483905963169e-06 -141.1125 122.268203029755 -1.15412262962316 0.250273255374403 RANGRF other 0.026991547302321 1 0.0685648522198162 4.66846655238398 -1.15412262962316 1.34109343256864e-07 330.425246826516 62.7573117460694 5.26512748288985 4.84283840265444e-07 -433.959520451342 286.391308257703 -1.51526777502917 0.131837446621929 DPH1 essential 0.00132097703108011 1 0.00540363908968182 5.26512748288985 -1.51526777502917 0.000223980139790358 64.1006923579361 16.149018835152 3.96932426745373 0.000109146951665516 -87.0148138471586 65.5163730279908 -1.32813844578947 0.186047724122003 MAP2K6 other 1 1 0.99345555405953 3.96932426745373 -1.32813844578947 2.57686771853164e-05 19.7154597055888 28.6710923490133 0.687642433207373 0.492699097696308 -280.765625 69.7783513886219 -4.02367810950864 8.90880201917194e-05 DHRS7B other 0.203912113347569 1 1 0.687642433207373 -4.02367810950864 3.80998644627718e-09 382.297979595518 56.937067451173 6.71439532644287 5.54272330042057e-10 57.5123769818209 389.686984235077 0.147586086547676 0.882901661140995 WSB1 other 4.16507718307021e-05 1 7.0547782167753e-06 6.71439532644287 0.147586086547676 0.92088101614316 5.07839537338779 15.3789875401206 0.330216495730899 0.741679422951585 -11.9310139073758 65.1532979722812 -0.183122179209589 0.854939936128707 MYH3 other 1 1 1 0.330216495730899 -0.183122179209589 8.98950131348571e-16 172.061303697989 18.6360995893548 9.23268857160822 1.89023329550101e-16 -105.057784099128 79.5261568663938 -1.32104691385537 0.188432644100664 NAT9 other 1.22095406839763e-11 1 2.66296066670182e-12 9.23268857160822 -1.32104691385537 1.7385265991833e-07 190.857756551791 32.8140981093917 5.81633406213182 3.33303489172009e-08 123.660272871268 140.338625436685 0.881156363663106 0.379597497452912 TMEM104 other 0.00169645425548306 1 0.000396564491416856 5.81633406213182 0.881156363663106 0.980369949140994 -0.020911456106707 4.56512727092303 -0.00458069509691432 0.996351959316941 5.78148016953888 29.216187449256 0.197886195095798 0.843433986324075 VTN other 1 1 1 -0.00458069509691432 0.197886195095798 5.97434986316272e-31 491.045508361699 31.9855687433483 15.3520955747838 3.07583757073862e-31 -368.705194612993 204.533558068618 -1.80266357313012 0.0737054105234203 TNFAIP1 other 8.66519704153121e-27 1 4.46765407149785e-27 15.3520955747838 -1.80266357313012 3.08094816582546e-21 139.286641014257 12.1172817447484 11.4948751665879 1.156454120189e-21 -101.447190567807 77.484654697244 -1.30925524497969 0.192705302013762 IFT20 other 4.38264876588671e-17 1 1.66240279777168e-17 11.4948751665879 -1.30925524497969 5.34233693649899e-19 393.502676236989 37.2475316965502 10.5645302739197 2.56160653896257e-19 -348.339573775345 238.181482664846 -1.46249645387214 0.145964235000916 TMEM97 other 7.50384646100648e-15 1 3.66079190483142e-15 10.5645302739197 -1.46249645387214 0.000769922372324213 761.259240965793 197.672782842809 3.85110802821627 0.000171258732333977 406.366721036546 861.034822522657 0.471951552256591 0.637620842616497 CDR2L other 1 1 1 3.85110802821627 0.471951552256591 0.292511792767054 -72.2424972169848 68.5656796658017 -1.0536247517578 0.293673573029397 -372.45564213827 282.009787491316 -1.32071884969503 0.188517036169632 PMP22 other 1 1 1 -1.0536247517578 -1.32071884969503 6.46613168226934e-09 25.1109359346374 4.17508034308609 6.0144796916833 1.57357578329083e-08 -58.1488458974777 26.763884696711 -2.17266090316939 0.0315386436427251 FOXN1 other 6.97307640615925e-05 1 0.000189836182496206 6.0144796916833 -2.17266090316939 1.46112463931962e-20 294.88708834083 25.9092919251911 11.3815186147221 1.68622646432094e-21 26.254900395543 166.088612595818 0.158077667006799 0.874630072374766 UNC119 other 2.07070583884376e-16 1 2.4226015612899e-17 11.3815186147221 0.158077667006799 1.75042897934985e-26 350.376213873178 25.4693147460541 13.7567978316912 1.58360016998008e-27 148.587113486416 163.268188191026 0.910080004762269 0.364390433635775 ALDOC other 2.52779448907911e-22 1 2.29416156625014e-23 13.7567978316912 0.910080004762269 3.44031345261726e-18 914.710445824454 88.3264630921709 10.3560180471614 6.88179688721795e-19 26.437606203853 355.52140587571 0.0743629097064707 0.940830887371956 SUPT6H essential 4.80611789330632e-14 1 9.81894779868257e-15 10.3560180471614 0.0743629097064707 1.88383765307802e-05 555.192788951712 119.382070491309 4.65055419684757 7.75136892388768e-06 -318.143263200173 480.522824661656 -0.662077318437856 0.509041994778476 RAB34 other 0.15114029490645 1 0.0794515314698487 4.65055419684757 -0.662077318437856 1.20821085263692e-07 394.167194244603 66.2189458901236 5.9524836728546 2.15534823996291e-08 68.4170263788967 287.218762405789 0.238205282293626 0.812083059088108 PHF12 essential 0.00119383314349054 1 0.00025859868183075 5.9524836728546 0.238205282293626 7.4011838831874e-13 305.436902764606 73.3529633299911 4.16393406481133 5.19082437011509e-05 -379.885002553067 127.006472230525 -2.99106806040209 0.00323809305473395 TMEM33 other 9.43206874073402e-09 1 0.490377178244773 4.16393406481133 -2.99106806040209 1.63810453211885e-11 268.803083715518 49.9196207031889 5.38471807135239 2.85851398956463e-07 -169.965317367963 94.5078681216624 -1.7984250491098 0.0741899201146435 SLAIN2 other 1.99914277099784e-07 1 0.00323126421380385 5.38471807135239 -1.7984250491098 5.20522621023455e-08 366.540206185566 119.763130414915 3.06054296439732 0.00263618615509911 -654.04611824111 227.108339191166 -2.879885963547 0.00458598568089352 OCIAD1 other 0.000528955087484035 1 1 3.06054296439732 -2.879885963547 2.68552995056647e-05 42.5928068958685 36.7168999073199 1.16003276429602 0.248113630890767 -178.289680967007 59.6810077879931 -2.98737718371565 0.00335145196775035 DCUN1D4 other 0.212130010795245 1 1 1.16003276429602 -2.98737718371565 0.000791734465202835 93.0607153472704 34.6454880628906 2.68608469819623 0.00815141840155213 -34.2456405429507 56.3140583251687 -0.608118852759811 0.544145721671735 USP46 other 1 1 1 2.68608469819623 -0.608118852759811 0.469700067213431 19.3307317356235 16.8178898571011 1.1494148136225 0.252166940643982 37.4014608599779 39.0630702320126 0.957463421022319 0.339834093659616 SULT1E1 other 1 1 1 1.1494148136225 0.957463421022319 1.73593150170636e-08 30.5354066764677 18.6724861395169 1.63531553582707 0.104213404977657 -124.308226664306 31.1000515514953 -3.99704246336947 0.000102984982670294 CHIC2 other 0.000182585275349475 1 1 1.63531553582707 -3.99704246336947 0.00289102326232764 151.88875432526 52.3900196662806 2.89919254264031 0.00430333480001104 13.9048442906573 91.8803277215506 0.151336468158851 0.879913643032892 NMU other 1 1 1 2.89919254264031 0.151336468158851 1.37516414888029e-07 207.601682255683 36.8370500323934 5.63567609439745 8.16366316797526e-08 123.813636286475 63.982114332275 1.93512886497436 0.0548189267743524 KIAA1211 other 0.00135329903891309 1 0.000952291308544314 5.63567609439745 1.93512886497436 9.37815679263799e-16 264.43963500234 71.5081534036031 3.69803473332337 0.000302314382226376 -409.567807562893 107.669302707831 -3.80394223109521 0.000205375183605195 LAMTOR3 other 1.27317856616853e-11 1 1 3.69803473332337 -3.80394223109521 6.8847811723431e-05 -23.921168854741 84.1594918594524 -0.284236136961113 0.776606353052732 -428.899373827819 124.070481087261 -3.45690102971524 0.000704270785383023 NFKB1 other 0.515670109808498 1 1 -0.284236136961113 -3.45690102971524 0.162642929644806 8.73845737171698 12.5095814495553 0.69854114679653 0.485906211348344 -73.4575785625268 50.6993627156308 -1.44888563934315 0.149429389272143 AREG other 1 1 1 0.69854114679653 -1.44888563934315 1.09351270553714e-05 161.293021032502 53.101352785799 3.03745596996612 0.00279473680676716 -57.1123326959878 78.3507416302856 -0.72893161580377 0.467129462877493 MANBA other 0.0900070307927617 1 1 3.03745596996612 -0.72893161580377 6.3979504788304e-15 791.267686424474 244.971268108315 3.23004282312248 0.00150768288102715 -1385.76840344168 361.453701788384 -3.83387525590481 0.000182195043760202 UBE2D3 essential 8.56621589610602e-11 1 1 3.23004282312248 -3.83387525590481 0.015434348904243 4.79042656870868 20.7358420418913 0.231021559627571 0.817602720127491 -64.6077791938421 31.0659333960346 -2.07969863226736 0.0391996557772872 MAPK10 other 1 1 1 0.231021559627571 -2.07969863226736 7.25881723439203e-16 262.15039549633 37.8911005416867 6.91852154592131 1.11079007345774e-10 -20.0207724649043 58.8088416728376 -0.340438136433342 0.733984605014844 ELF2 other 9.87997613773099e-12 1 1.44524896457586e-06 6.91852154592131 -0.340438136433342 2.85715246365191e-05 19.1486683450367 121.560406869436 0.157523891521716 0.87503699833994 -661.467901152778 188.403893146545 -3.51090357054498 0.000585071668446761 NDUFC1 other 0.22474361279086 1 1 0.157523891521716 -3.51090357054498 1.04835616764419e-08 217.303381592732 46.2757360567122 4.69583846978513 5.80567758895324e-06 -23.7726140793787 73.1683631699947 -0.324902909528629 0.745692660978891 TBC1D9 other 0.000111597514045724 1 0.0601758482095003 4.69583846978513 -0.324902909528629 4.41016896687393e-15 205.399427986948 32.1990548772597 6.37905145880571 1.95378376841058e-09 -51.4177640904768 50.8506202273863 -1.01115313560689 0.31351898900077 ZNF330 other 5.922415905615e-11 1 2.44320660239743e-05 6.37905145880571 -1.01115313560689 0.0144952375343172 46.2243765233451 33.7229818436325 1.37070846041075 0.172422299626673 -64.7843769237314 54.5923710884238 -1.18669285894909 0.23714137058841 INPP4B ts 1 1 1 1.37070846041075 -1.18669285894909 4.41904057701809e-12 172.770158368699 25.6749138023544 6.72914268373729 3.1152470219778e-10 38.2796708415281 41.4202284841299 0.92417816710487 0.35683007114991 GAB1 other 5.4972864778105e-08 1 3.99312363277114e-06 6.72914268373729 0.92417816710487 2.89704588181006e-07 87.2365678437715 34.1158638983805 2.55706753033192 0.0115036638913822 -118.946676110494 51.6161013572433 -2.30444905722818 0.0225079264233512 KLHL2 other 0.00276783763548133 1 1 2.55706753033192 -2.30444905722818 0.00202437112307814 1048.11231407466 308.733214141778 3.39488032406304 0.000869510884806169 600.453139228965 467.102487011798 1.28548478315809 0.200515864587969 CPE other 1 1 1 3.39488032406304 1.28548478315809 3.80327822167337e-09 642.386667214649 983.76195637154 0.652989946454117 0.514723945486827 -6671.77808145988 1485.15494179625 -4.49231113448038 1.36453471320058e-05 RPL34 essential 4.15850440757767e-05 0.19789846945548 1 0.652989946454117 -4.49231113448038 0.000512059188914577 195.324643493761 96.7158242824727 2.01957275288568 0.045162066506976 -301.381144590703 184.275024413342 -1.63549643013306 0.10398730593854 WFS1 other 1 1 1 2.01957275288568 -1.63549643013306 4.03590045014383e-09 103.33725696898 36.0822956198618 2.86393244093087 0.00477605287607584 -218.571908640821 68.8717180762606 -3.17360906255889 0.00182244105585335 GRPEL1 essential 4.40478175128698e-05 1 1 2.86393244093087 -3.17360906255889 1.25417096580878e-12 170.429501084599 32.1398785850021 5.30274253008936 3.8697468725491e-07 -49.7338911269496 48.9166186927716 -1.01670745967359 0.310876986811431 GAR1 essential 1.58778044271392e-08 1 0.00433914716818931 5.30274253008936 -1.01670745967359 5.51971472039742e-07 123.220813786165 32.832240289661 3.75304312770175 0.000248093199623586 -45.4793979667045 54.8986470718482 -0.828424749833702 0.408728894330317 FRG1 other 0.0051471339767706 1 1 3.75304312770175 -0.828424749833702 7.12992788097556e-15 328.440030345177 52.508054143793 6.25504097801351 3.69688616152179e-09 -88.526261221393 80.1611618483406 -1.10435351958694 0.271151238331779 CLCN3 other 9.53699153359291e-11 1 4.57674506796397e-05 6.25504097801351 -1.10435351958694 0.0259079280107031 39.2711905510983 15.5190715112597 2.53051160455092 0.0124003069590714 18.9363693566143 23.8441619490862 0.794172149855745 0.428325282752172 AADAT other 1 1 1 2.53051160455092 0.794172149855745 2.65932047834909e-09 239.674104671311 59.3480434818637 4.03844997425322 8.53351050566588e-05 -128.815703572687 91.8219068887675 -1.40288639103013 0.162703513131319 GALNT7 other 2.93482607990605e-05 1 0.786277657992054 4.03844997425322 -1.40288639103013 1.09978780799422e-14 848.277125160188 121.611257858388 6.97531741796454 8.94330300638035e-11 -71.0304551279561 222.073575641058 -0.319850999484801 0.749523409674764 DHX15 essential 1.4655772329331e-10 1 1.1671904753627e-06 6.97531741796454 -0.319850999484801 0.295606506166893 -209.863280935871 188.793270171684 -1.11160361142654 0.268052317685889 -532.422338065349 343.553497031965 -1.54975089080759 0.123267345741697 SOD3 other 1 1 1 -1.11160361142654 -1.54975089080759 1.65265524419262e-12 78.0729221620065 12.7176355578835 6.13894947741368 6.91541964187185e-09 -13.342285741691 23.1001863841647 -0.577583467068355 0.564399962074918 SEPSECS essential 2.08416352845132e-08 1 8.48107064879164e-05 6.13894947741368 -0.577583467068355 0.702818669252885 0.219922480257159 86.7467454012992 0.00253522456940344 0.997980576752023 112.266534970485 164.323528706727 0.68320426085086 0.495538751486188 CPZ other 1 1 1 0.00253522456940344 0.68320426085086 2.83191959718067e-05 329.754155856632 112.637326871875 2.92757441084987 0.00393805842619507 -183.481147304703 174.59106999432 -1.0509194273835 0.294952647107227 TRIM2 other 0.222872072298118 1 1 2.92757441084987 -1.0509194273835 0.00851125599611536 -11.7282736409469 20.3755107817603 -0.575606362292805 0.565749578912222 -109.405850493626 38.4770237953233 -2.8434073039434 0.00509056788758428 SLC2A9 other 1 1 1 -0.575606362292805 -2.8434073039434 1.74604580441089e-13 99.6389395440713 15.5586734841336 6.40407677721891 1.78820142215682e-09 -5.73057718935272 24.2904280694771 -0.235919151896449 0.813812992976103 FBXW7 ts 2.26444680374048e-09 1 2.23847054025591e-05 6.40407677721891 -0.235919151896449 1.09876956569483e-07 61.3113982319401 12.6505446719178 4.84654217047601 3.03994232622158e-06 12.5394413349376 19.9512628127041 0.628503641732043 0.53060510961518 NEIL3 other 0.00108943002438642 1 0.0321929892346865 4.84654217047601 0.628503641732043 1.63373484949224e-11 32.2220299359384 8.12478441989543 3.96589352660672 0.000112590436338985 -43.8325439475361 14.4213334089061 -3.03942379700247 0.0027944618695064 TBC1D19 other 1.99397338380528e-07 1 1 3.96589352660672 -3.03942379700247 1.67263257242752e-08 968.827257107047 163.490595536037 5.92588982828371 2.04738896410098e-08 460.864701923809 306.225430825122 1.50498507155991 0.13443070181373 NSD2 other 0.000176011125596548 1 0.000245891414588528 5.92588982828371 1.50498507155991 9.43405967917789e-06 825.001224199285 412.120761702274 2.00184339364899 0.0470807641200993 -1454.88231553974 646.337194468603 -2.2509648647652 0.0258219816895121 SH3D19 other 0.0781423163226305 1 1 2.00184339364899 -2.2509648647652 3.48917975523515e-05 224.335519324772 63.9848209709566 3.50607403319297 0.000599030486333267 -56.5177459999394 113.571805557299 -0.497638878968296 0.619462508336863 STIM2 other 0.271213942374428 1 1 3.50607403319297 -0.497638878968296 0.466496850158571 -3.12362301101587 6.69275987863504 -0.466716730864236 0.641379714780976 -15.1235548854013 12.5730009925244 -1.20285959528624 0.230925838344996 NKX3-2 other 1 1 1 -0.466716730864236 -1.20285959528624 2.25412631092647e-08 636.48287929894 153.750011120253 4.13972574480743 5.83556005283863e-05 -439.066076195213 292.793142600322 -1.49957773018803 0.135868424465707 MFSD10 other 0.00023512791549274 1 0.547375532956264 4.13972574480743 -1.49957773018803 0.000454328075606465 33.1743534933432 16.9981182329159 1.95164859067181 0.0527595129522982 -38.1191709844559 26.5749122412528 -1.4344043975913 0.153445740569786 GLRB other 1 1 1 1.95164859067181 -1.4344043975913 0.0140450682782472 -37.281972265023 37.5389886249298 -0.993153348842858 0.322245340306127 -200.657992607674 70.8218343095985 -2.83327867124277 0.00524602652852797 BST1 other 1 1 1 -0.993153348842858 -2.83327867124277 2.88808590680026e-11 260.219254476079 40.4719700525877 6.42961669861783 1.46357066971722e-09 68.3356202915562 62.1123574869026 1.10019363386691 0.27293181142222 RAPGEF2 other 3.49342871286559e-07 1 1.83765933289694e-05 6.42961669861783 1.10019363386691 0.00781913410499342 45.7321039873354 16.2930666363213 2.80684446998991 0.00568175238978052 13.9631072523994 30.4709470368563 0.458243297640543 0.647454359125722 HGFAC other 1 1 1 2.80684446998991 0.458243297640543 2.53305249820353e-08 72.4783107949918 18.1349281623741 3.99661416610229 9.88378153714167e-05 -36.3856676217129 29.4714458830941 -1.23460748298695 0.218833064797184 SNX25 other 0.000263082832463419 1 0.904761361909949 3.99661416610229 -1.23460748298695 0.00199066835557485 2.84353636653864 19.2698839980589 0.147563751127151 0.882876400213598 -84.5443697090455 31.3501281841088 -2.69677907575193 0.00776588455143164 LRP2BP other 1 1 1 0.147563751127151 -2.69677907575193 9.67424958432212e-12 91.9953379055249 21.5468400589531 4.2695512499198 3.37883708680223e-05 -81.1760036988522 35.0545025532438 -2.3157083337741 0.0218682347979987 UFSP2 other 1.19021421117132e-07 1 0.325314434717319 4.2695512499198 -2.3157083337741 1.35297001502213e-05 285.966008109741 74.8210322770755 3.82200030401557 0.000191683854846032 -31.350099214908 130.599364810017 -0.240047868996247 0.810612377911361 KLF3 other 0.110294115624604 1 1 3.82200030401557 -0.240047868996247 0.000592129817932739 82.1329573037799 35.7578650498328 2.29692005351321 0.0229707649846404 -77.506996341523 62.4149964301053 -1.24180086156567 0.216197972567162 KLHL5 other 1 1 1 2.29692005351321 -1.24180086156567 0.0042794431290136 13.1953424753098 15.8049052429508 0.834889059597188 0.405048810527818 -54.307829146029 26.8308183434193 -2.02408396385528 0.044657118713874 FAM149A other 1 1 1 0.834889059597188 -2.02408396385528 2.21855822280761e-07 249.899563605102 45.7844334258606 5.45817748317816 1.94653775850326e-07 143.989368186641 83.9381279474112 1.71542267748518 0.0883326104988064 NCAPG essential 0.00214334909905443 1 0.00222372473531413 5.45817748317816 1.71542267748518 3.08038721290205e-05 65.6905640263151 64.151816985916 1.02398602428887 0.307437339039411 -340.873158369687 110.117197810342 -3.09554878936152 0.00233180306456683 UGDH other 0.241132711025973 1 1 1.02398602428887 -3.09554878936152 0.459813275937402 -13.280569201196 11.5532365658295 -1.14951071290927 0.252162882164453 -22.8036119956506 21.0972947700978 -1.08087848438139 0.281474438116468 PPARGC1A other 1 1 1 -1.14951071290927 -1.08087848438139 0.000796875341582144 41.5260734118922 11.7757617227931 3.52640231599748 0.000556177225747768 -14.5485913585264 32.7455347926986 -0.444292373009903 0.657458998589082 DDX25 other 1 1 1 3.52640231599748 -0.444292373009903 0.0192986703290861 92.602598643884 404.037799715872 0.229192908953084 0.819029121959869 -2425.28966014005 1038.95773899513 -2.3343487122833 0.0208951048848384 CRYAB other 1 1 1 0.229192908953084 -2.3343487122833 1.60842618548763e-06 -28.9830042446431 51.3362684222237 -0.564571698243969 0.573181232135256 -391.856008661134 83.5879188632057 -4.68795029222367 6.00499145449369e-06 HTATIP2 other 0.0144034564910417 0.0873305907227018 1 -0.564571698243969 -4.68795029222367 0.0922831546752881 312.376497695854 177.549183370388 1.75938008706129 0.0804733350438733 -344.618433179721 556.966431455603 -0.618741837419319 0.536988883004347 CTSC other 1 1 1 1.75938008706129 -0.618741837419319 1.63195259408003e-06 138.444567234765 38.1865526933008 3.62547958562003 0.00039145030620472 -97.2366606819006 64.9779211895354 -1.49645693339849 0.136581256729484 CCDC34 other 0.0146010798592341 1 1 3.62547958562003 -1.49645693339849 0.217497270481889 7.02274459229728 9.84388062331356 0.713412206123783 0.476699204468792 -26.948209156457 26.2029792406238 -1.02844065588839 0.305398115629091 ZBTB16 other 1 1 1 0.713412206123783 -1.02844065588839 1.82120489951448e-06 -1.30085210346524 21.5880033494639 -0.060258101798819 0.952028198716546 -163.725031817268 35.1602855885931 -4.65653304791088 6.89756319255383e-06 ELP4 other 0.0162305780644731 0.10028367125654 1 -0.060258101798819 -4.65653304791088 1.22788003569081e-12 172.584944548454 36.4983492020324 4.72856850574611 5.45436004584891e-06 -360.307418165943 98.4970969613267 -3.65805114345057 0.000358941236629515 ZPR1 other 1.55498727719884e-08 1 0.0566598921562785 4.72856850574611 -3.65805114345057 8.52506519462913e-05 236.616789174307 94.8664103094518 2.49421042076399 0.0137232064168867 -440.134348602778 190.173492526207 -2.31438326528143 0.0220222591095785 MTCH2 other 0.630769573750609 1 1 2.49421042076399 -2.31438326528143 0.00156228196281627 81.2102667407614 83.8494734228127 0.968524469214695 0.334384195903414 -466.043854774475 166.602587941846 -2.79733862799988 0.00584764807296985 FNBP4 essential 1 1 1 0.968524469214695 -2.79733862799988 0.0131073410640655 8.28658657664815 4.25220830661709 1.94877249163757 0.0532012425013574 -15.7767263204925 11.9034936860982 -1.32538620480118 0.1870717547889 TECTA other 1 1 1 1.94877249163757 -1.32538620480118 5.94692452870617e-06 302.110712032229 76.6849255677755 3.93963624265656 0.000124359669028948 -317.177571227491 214.55160653828 -1.478327645013 0.141403023219543 SC5D other 0.0501563614751078 1 1 3.93963624265656 -1.478327645013 0.76820600885216 -2.78287907745703 6.42636447191259 -0.433040965793338 0.665586996580861 -11.8805636329526 17.1272322414916 -0.69366512145327 0.488930462875294 CRTAM other 1 1 1 -0.433040965793338 -0.69366512145327 0.349597771484352 4.61603433288385 24.2085568066257 0.19067779916647 0.849070984236654 -85.418058987399 66.0762047666891 -1.29272041711543 0.19836593663761 B3GAT1 other 1 1 1 0.19067779916647 -1.29272041711543 0.337662584679561 1255.62839167763 1024.23582110124 1.2259172797995 0.222101157964806 -1034.68880791664 2699.54159714654 -0.383283150372759 0.702038406419722 HSPA8 other 1 1 1 1.2259172797995 -0.383283150372759 0.00256862222893586 150.855209207723 53.1855282489764 2.83639580491759 0.00516837251673617 -161.874865478573 146.225604393705 -1.10702134656755 0.269988772148344 VWA5A other 1 1 1 2.83639580491759 -1.10702134656755 0.0274699103952613 223.488994882856 88.9838548910355 2.51156791483722 0.0131080506352518 -84.224430563899 276.492310938932 -0.304617623100923 0.761091174364573 DNAJC4 other 1 1 1 2.51156791483722 -0.304617623100923 1.21366061607931e-05 337.202416830288 71.3933488505672 4.72316290325705 5.26437278755624e-06 17.101056706821 197.700145109133 0.0864999704344219 0.931183575001676 SIAE other 0.0993866678507349 1 0.0547494769905848 4.72316290325705 0.0864999704344219 0.000340663342182181 101.372977190042 32.6388060219108 3.10590335694233 0.00228520332073086 -169.321000146762 99.195292097783 -1.70694593025495 0.0899874917714107 SNX15 other 1 1 1 3.10590335694233 -1.70694593025495 0.167813527079035 20.7082631638038 14.0120944720299 1.47788492328112 0.141494195966765 -38.0403727405412 52.8168967537247 -0.720231120694506 0.472481581895216 LPXN other 1 1 1 1.47788492328112 -0.720231120694506 0.0190980129697027 78.3573388203018 91.0349320526875 0.860739246501021 0.390746316702605 -806.978160722452 342.651434463186 -2.35509932122917 0.0198038608832422 DTX4 other 1 1 1 0.860739246501021 -2.35509932122917 1.55770136316511e-05 271.1088976603 72.6360922594617 3.73242680363198 0.000272297627266627 -437.694185893821 220.754349398747 -1.98272055380081 0.0493013065720431 ATG2A other 0.126033617293689 1 1 3.73242680363198 -1.98272055380081 0.00230698183712577 239.780770171897 92.7489798663432 2.58526584893371 0.010716514195666 -457.83723313146 282.077421118961 -1.62309067955629 0.106742147209367 EHD1 other 1 1 1 2.58526584893371 -1.62309067955629 1.53668745756077e-05 205.376224226804 56.5600691274288 3.63111692392199 0.000387422910603182 -413.43530927835 202.711401555629 -2.03952666749676 0.0431644048566533 OSBP other 0.124394849689544 1 1 3.63111692392199 -2.03952666749676 0.206968328928497 21.4654339772434 186.813471998784 0.114903029998731 0.908672640122024 -998.825661550675 581.291113965471 -1.71828819941329 0.0877669402388308 UNC93B1 other 1 1 1 0.114903029998731 -1.71828819941329 1.75187036406021e-12 57.4975393922976 8.51257363791185 6.75442490579169 2.81273096905544e-10 -50.7359446250396 23.6714008653985 -2.14334356101428 0.0336662666811835 PUS3 other 2.20718147167945e-08 1 3.61154656426719e-06 6.75442490579169 -2.14334356101428 1.63536802380982e-06 64.2735779827115 15.1744994575492 4.23563084650781 3.92048479783376e-05 -75.736539661628 43.1099163555088 -1.75682409209662 0.080948247540491 DCPS other 0.0146300023410026 1 0.374602322433016 4.23563084650781 -1.75682409209662 4.01513894528e-08 334.916350659426 58.7415873331753 5.70152026637994 5.99896400918162e-08 -187.461697439876 175.366881517538 -1.06896864343869 0.286778465498946 KMT5B other 0.000411310833554483 1 0.000705538157119851 5.70152026637994 -1.06896864343869 2.66813921550568e-08 147.3777653839 29.6283000732278 4.97422278766075 1.75182979517303e-06 -162.539796340608 82.9689292869403 -1.95904415951276 0.0519374620484548 FOXRED1 other 0.000276877351110067 1 0.018851440425857 4.97422278766075 -1.95904415951276 6.49351347168823e-05 344.661242491066 82.4623349203861 4.17962022084169 4.87958261578286e-05 -202.129647935518 251.538477504568 -0.803573472896794 0.422881938873003 PPP6R3 other 0.487662861723786 1 0.462344715412384 4.17962022084169 -0.803573472896794 0.942688132497084 -20.5596410978186 98.6204931292328 -0.208472300689849 0.83515276469702 -96.0172413793105 299.686896077793 -0.32039185775539 0.749132542915079 NRXN2 other 1 1 1 -0.208472300689849 -0.32039185775539 0.99483666000751 3.62017351156107 64.9490570771032 0.0557386615676875 0.9556231987901 -13.6640280001494 215.046696968429 -0.0635398180617272 0.949420135359159 MS4A6A other 1 1 1 0.0557386615676875 -0.0635398180617272 0.88358104393399 6.13847414081988 21.2708429386215 0.288586313129803 0.773291145514706 33.4703578210521 70.4278818128887 0.475242999782039 0.635295983087246 MS4A4A other 1 1 1 0.288586313129803 0.475242999782039 0.0551421800103003 74.449204066196 32.4209832123452 2.29632776953684 0.0230054618661713 0.817608531218403 92.0781735641821 0.00887950422527112 0.992926766142577 ST3GAL4 other 1 1 1 2.29632776953684 0.00887950422527112 0.0525570766572133 228.599267613886 93.9892991684537 2.43218397877588 0.0161545295743103 69.0104291782627 286.611126304335 0.240780705439134 0.810045340043831 CPT1A other 1 1 1 2.43218397877588 0.240780705439134 0.00637382486016333 1655.49998946215 525.143258827599 3.15247308545502 0.00194405576094141 146.985668521328 1575.19760055103 0.0933125269298978 0.925775786114267 CCND1 og 1 1 1 3.15247308545502 0.0933125269298978 0.00137140713656521 104.048220351499 36.9588784588774 2.81524290482108 0.00551586038969476 -172.921030866932 122.548198522582 -1.41104506595475 0.160261469761919 CCDC86 essential 1 1 1 2.81524290482108 -1.41104506595475 0.000976661998948174 318.142353494203 130.99999818003 2.42856761766505 0.0163495337959195 -866.629692886243 428.088937686952 -2.02441506096563 0.0447139930423571 PRPF19 essential 1 1 1 2.42856761766505 -2.02441506096563 0.010075142255869 120.498195646269 111.580666992462 1.07992001566373 0.281911136793585 -874.854658336891 365.073375355992 -2.39638033719605 0.0177896558005398 TMEM109 other 1 1 1 1.07992001566373 -2.39638033719605 0.0961994178063013 19.0585411596597 10.3329654832244 1.84444061006507 0.0670277870151585 4.80281709794814 16.3805415683753 0.29320258294882 0.769759492717509 CCKBR other 1 1 1 1.84444061006507 0.29320258294882 1.09356553805775e-08 0.837370783004983 14.2372035247357 0.058815678342319 0.953174679885398 -110.405880908258 22.5698135286499 -4.89174980414038 2.48014563249639e-06 TRIM3 other 0.000116300694972442 0.0361357218654725 1 0.058815678342319 -4.89174980414038 6.52783964429137e-05 47.015362840082 22.8855828398872 2.05436598093273 0.0416306354472938 -213.601775051195 70.5768433558113 -3.0265135828522 0.00290051498399772 CHORDC1 essential 0.490110200493396 1 1 2.05436598093273 -3.0265135828522 0.00581398054249896 3198.59636692186 989.44390522484 3.23272127912599 0.00150580155461738 1870.62756193827 3558.5187222041 0.52567590842395 0.599884525957241 FOLR1 other 1 1 1 3.23272127912599 0.52567590842395 7.94555592056223e-05 119.411751755425 33.100998716538 3.60749694527386 0.000418871189440693 -176.162359691112 119.700282704183 -1.47169543556105 0.143170526584671 ANAPC15 essential 0.590910993812213 1 1 3.60749694527386 -1.47169543556105 0.249224139293215 31.3704421502078 18.8390744902876 1.66517958015298 0.0979367681064573 22.1215637873811 68.1261179363119 0.32471487378837 0.745843341145247 FOLR3 other 1 1 1 1.66517958015298 0.32471487378837 2.53745609777472e-07 68.3057605400149 14.673053914569 4.65518364055035 6.90601314957939e-06 -46.4949874149076 41.0711545310635 -1.13205942091893 0.259357748225871 PANX1 other 0.0024384953099615 1 0.0710766873354711 4.65518364055035 -1.13205942091893 8.18840574163874e-10 762.089900491821 122.166865928299 6.23810633677958 4.23908587174376e-09 -564.312184441432 488.823263960646 -1.15442988508596 0.250147720306429 ARHGEF17 other 9.28483327044416e-06 1 5.23611886877789e-05 6.23810633677958 -1.15442988508596 4.78434868350382e-09 353.84345313152 67.6317787051784 5.23191109129335 5.478382516298e-07 -340.841109221425 188.192472025418 -1.8111304110793 0.0720951744621421 CEP164 other 5.20058701896865e-05 1 0.00608648297560708 5.23191109129335 -1.8111304110793 2.01648114631429e-09 88.4815271241536 41.528548101975 2.13061932497336 0.0346881847556643 -237.968405468666 64.9268239065772 -3.66517859877263 0.000338312833306382 RNF141 other 2.24152044224297e-05 1 1 2.13061932497336 -3.66517859877263 0.259204381107614 -3.72194799738054 12.2658740596961 -0.303439280337169 0.761962026090526 -53.4520022409048 33.9579304490573 -1.57406536658916 0.117511288552124 CEP126 other 1 1 1 -0.303439280337169 -1.57406536658916 2.28650892026616e-08 3674.94745797883 1001.26689510147 3.67029757595892 0.000332139971144316 -2672.88567475964 1560.28785485811 -1.71307215296033 0.0886858942420599 EIF4G2 essential 0.000238231364402531 1 1 3.67029757595892 -1.71307215296033 0.696027576209996 11.759231450938 27.0762403332186 0.434300748782731 0.664677941984958 63.5518192112651 75.44737367031 0.842333087550189 0.400907787215316 IL10RA other 1 1 1 0.434300748782731 0.842333087550189 0.0252708418299727 -45.5963868307957 39.9644931599282 -1.14092243453032 0.255650659977909 -165.64834801548 62.076762764138 -2.66844372418169 0.00842577051322862 GALNT18 other 1 1 1 -1.14092243453032 -2.66844372418169 5.98978223839551e-15 313.46356013836 48.4201363950886 6.47382645890595 1.19462862080703e-09 -337.174285213888 136.870432995789 -2.46345596951725 0.0148538747829232 BIRC2 other 8.0251102430023e-11 1 1.5030817306994e-05 6.47382645890595 -2.46345596951725 3.60539580879758e-18 405.459390229155 48.2725924637554 8.39937052342044 2.76107999748943e-14 -299.507145089528 133.772294438918 -2.23893255584613 0.0265934342022103 UBE4A other 5.03493524698582e-14 1 3.82105860852562e-10 8.39937052342044 -2.23893255584613 1.02958612949535e-06 351.394509547598 82.7845628713594 4.24468641688231 3.79421182231302e-05 -403.676591027863 234.355594806521 -1.7224960699621 0.0870136320279295 DDX6 essential 0.00938467757035015 1 0.363106071395356 4.24468641688231 -1.7224960699621 0.16892314136511 45.7925162865435 24.5531587206887 1.86503564805934 0.0641431014222848 25.1949776410359 69.5474183058964 0.36227049478988 0.717663209516301 UPK2 other 1 1 1 1.86503564805934 0.36227049478988 9.71035241235452e-13 329.264474094881 44.5061774069472 7.39817466425423 9.32870237264618e-12 -83.4675405742822 125.675945246976 -0.664148898265719 0.507621459938971 CBL other 1.23331185989315e-08 1 1.24398246139237e-07 7.39817466425423 -0.664148898265719 0.00206820225469148 246.795898477157 69.7849880347166 3.53651846088132 0.00053780625774476 147.469040406092 195.909054668152 0.752742340857534 0.452768972927709 NECTIN1 other 1 1 1 3.53651846088132 0.752742340857534 0.000212517687098993 270.87142136963 125.742158661518 2.15418141578737 0.0327710758606079 -452.559848364244 209.489439977026 -2.16029909867473 0.0322860739879084 HIPK3 other 1 1 1 2.15418141578737 -2.16029909867473 0.516220851158384 -2.33198015336038 25.6225377704171 -0.0910128486981021 0.927599892993724 -44.9061231393775 42.687759980039 -1.05196719528914 0.294451844110102 KIAA1549L other 1 1 1 -0.0910128486981021 -1.05196719528914 2.54728707542354e-06 26.5268866401119 36.056797734484 0.735697241764265 0.463034003202192 -254.9632899128 59.9001962554943 -4.25646835655258 3.59581379736211e-05 FBXO3 other 0.0223422549385398 0.518480391441643 1 0.735697241764265 -4.25646835655258 8.5004688295165e-07 98.7264678471575 27.5469862444026 3.58392990693195 0.000452019945582268 -96.4787200994097 46.5778268760036 -2.07134438358941 0.0399733865849035 PDHX other 0.00779918015108139 1 1 3.58392990693195 -2.07134438358941 0.0112384850917308 35.5653128322243 12.6181195373417 2.81859057738148 0.00545304666699679 6.23600556496175 21.2769810405582 0.293086954069033 0.769847705277329 SLC1A2 other 1 1 1 2.81859057738148 0.293086954069033 0.00132273916652646 115.114484994385 54.3270190550545 2.11891775025848 0.0357016888248161 -152.989989388408 90.6677215596326 -1.68736995654827 0.0935566403371922 COMMD9 other 1 1 1 2.11891775025848 -1.68736995654827 0.201204697009442 46.0340018802885 175.252948162426 0.262671768794576 0.793166417421384 -920.950955813225 572.701140821817 -1.60808297760971 0.109933913964071 SLC15A3 other 1 1 1 0.262671768794576 -1.60808297760971 0.570323046457119 6.21110450128818 13.1683926788903 0.47166762510393 0.637849403013639 -32.1089034304984 42.6349311833622 -0.75311258959012 0.452562643978924 CD5 other 1 1 1 0.47166762510393 -0.75311258959012 0.00396684568169838 43.1299490717923 34.4428489392026 1.25221781589333 0.212426563077684 -124.971860405079 60.2506149558533 -2.07420057864385 0.0397583714079888 ACCS other 1 1 1 1.25221781589333 -2.07420057864385 2.45973548269361e-21 6696.01341636355 573.557167024424 11.6745353407438 3.01674650206191e-22 3866.29493966849 3757.74762106936 1.02888627165659 0.305359511174953 MDK other 3.50094151251782e-17 1 4.34109821646709e-18 11.6745353407438 1.02888627165659 5.76374528924188e-67 501.185222095006 15.3736293082879 32.6003191598238 2.95446011445623e-67 -7.50581465990568 99.5039734807808 -0.0754323108650071 0.939978434584905 AMBRA1 other 8.42256099116916e-63 1 4.31705711924344e-63 32.6003191598238 -0.0754323108650071 0.000246080318311358 119.153578898855 56.5831497060482 2.10581382474928 0.0369087743670918 -278.919582609518 113.803861073341 -2.45087978543863 0.0154157373590157 MADD other 1 1 1 2.10581382474928 -2.45087978543863 3.71943480213439e-06 223.194596774193 66.0394813303462 3.37971456283427 0.000929344744436076 -298.144784946237 132.897430370781 -2.24342023855855 0.0263647414566327 PTPMT1 essential 0.032065844793875 1 1 3.37971456283427 -2.24342023855855 0.00028960410569792 173.006235183079 50.5020484394042 3.42572708492536 0.000796466702001556 -240.093460861035 167.846528028561 -1.43043447893174 0.15472905692619 NAA40 other 1 1 1 3.42572708492536 -1.43043447893174 5.90890170600799e-12 115.258179231863 55.6339824253741 2.07172260922481 0.0399923285001947 -382.913580018843 88.0050990636958 -4.35103856586424 2.48353714877711e-05 CARS other 7.3199474334027e-08 0.359169142456145 1 2.07172260922481 -4.35103856586424 0.0127265911222363 -228.009118655564 112.36002358754 -2.02927261294067 0.0441988858029551 -564.175352963852 188.295809535574 -2.99621831391454 0.00319948575523945 SLC22A18 other 1 1 1 -2.02927261294067 -2.99621831391454 0.0858120807582478 945.41957868579 1509.42036278633 0.626346114041143 0.532046334349482 -3307.67030965911 2567.75922875891 -1.28815438480882 0.199689064769072 CD81 other 1 1 1 0.626346114041143 -1.28815438480882 4.86510664149777e-07 229.881552794629 53.8988797542722 4.26505251765288 3.47441475667772e-05 -189.33751464809 146.759221656324 -1.29012345875937 0.198941648382134 SLC35F2 other 0.00455957794441171 1 0.334134467149696 4.26505251765288 -1.29012345875937 0.00319975955597236 25.1274572387731 7.93530482906881 3.16653963269635 0.00187131239061996 11.9968851702183 13.4991899607365 0.888711486030807 0.375590631860496 C11orf21 other 1 1 1 3.16653963269635 0.888711486030807 1.20765682599789e-09 246.950175555927 127.408039286067 1.93826211391146 0.0544084743383045 -854.89369209393 196.811685457903 -4.34371409454135 2.52166160850527e-05 C11orf58 other 1.35788933515203e-05 0.364657485205947 1 1.93826211391146 -4.34371409454135 0.0164665863100435 381.829422117925 132.063696452759 2.89125196684548 0.00440759338432212 332.103666764447 428.092010345072 0.775776372226028 0.43910244221033 PITPNM1 other 1 1 1 2.89125196684548 0.775776372226028 5.23435631574015e-05 -146.54144714467 895.294713685696 -0.163679562611732 0.870196636814871 -5277.55211844939 1375.82992481971 -3.83590444083483 0.000181638011269058 RPS13 essential 0.397811079996252 1 1 -0.163679562611732 -3.83590444083483 0.00979946139303357 149.455558814902 60.0987351151171 2.48683368341489 0.0139840566427599 -269.189586388971 194.813480355895 -1.38178110620067 0.169093399567642 AIP other 1 1 1 2.48683368341489 -1.38178110620067 2.39992711157318e-15 608.605072463769 125.992830192143 4.83047385740621 3.2950986919417e-06 -570.066594202897 196.241669500487 -2.90492124151788 0.00422195387196395 NUP98 essential 3.23726168080106e-11 1 0.0348094225816721 4.83047385740621 -2.90492124151788 0.352341341527483 58.502679915689 157.67719274866 0.371028167713153 0.711133160778695 -633.023185787413 490.046177626213 -1.29176231687753 0.198400176659669 TCIRG1 other 1 1 1 0.371028167713153 -1.29176231687753 0.0339816533369562 111.458643910008 46.3399065795566 2.40524101443007 0.0173638524723052 -70.3473824670287 138.342957274519 -0.508499918267873 0.611840036997241 CHKA other 1 1 1 2.40524101443007 -0.508499918267873 2.61876012176304e-09 105.548193703646 19.9082232393177 5.30173850447859 3.86060772569216e-07 -46.5517464070316 52.4337628373143 -0.88782005883246 0.376004345194682 EXPH5 other 2.89189680246293e-05 1 0.00432928550359118 5.30173850447859 -0.88782005883246 3.04266923399841e-51 134.421618377589 5.98077333487226 22.4756249486689 8.7579908766175e-51 -27.3131225396034 34.6469955434582 -0.788325859462882 0.43170242072541 HPS5 other 4.43955867932707e-47 1 1.27787844880726e-46 22.4756249486689 -0.788325859462882 2.57061970272023e-77 327.305776946463 9.15492702087894 35.7518717735272 4.75992029504486e-77 -6.54499339770945 53.0881857282206 -0.123285309300564 0.902039868501811 GTF2H1 essential 3.75876012931752e-73 1 6.95947946338509e-73 35.7518717735272 -0.123285309300564 0.560300718911988 -23.7849114270203 22.0615753540566 -1.07811482386487 0.28267933819654 -32.2225651646458 57.0447653010494 -0.564864540937169 0.572993171651 POU2AF1 og 1 1 1 -1.07811482386487 -0.564864540937169 0.333972672244522 9.38901811289871 6.34148052770371 1.48057193771729 0.140750500861026 9.51283625164221 10.1258476161907 0.939460735754274 0.348955945976376 PTPN5 other 1 1 1 1.48057193771729 0.939460735754274 0.375425706113518 -26.9179081409227 79.438310394429 -0.338852979214553 0.735179100292523 -478.379156971003 342.478616835416 -1.39681467237675 0.164466024913268 VWF other 1 1 1 -0.338852979214553 -1.39681467237675 7.27686845305843e-10 39.0894278431927 30.1359321796499 1.29710365719461 0.196535432137985 -349.450602805272 66.9621774384901 -5.21862663630181 5.74291044828788e-07 PSMD9 other 8.27234405743682e-06 0.00838292638136582 1 1.29710365719461 -5.21862663630181 6.8176941842457e-07 166.013721979517 31.5202754453733 5.26688677791632 5.07457014934173e-07 -29.0847726133353 139.90697302128 -0.207886511910393 0.835617550289242 P3H3 other 0.00630909419810097 1 0.00565459351741149 5.26688677791632 -0.207886511910393 9.82220421419312e-17 292.634917767481 31.1249799198652 9.40193113444259 1.09391544610084e-16 -637.758589924277 397.820716805837 -1.60313066409647 0.111081920498527 PPFIBP1 other 1.35143707783083e-12 1 1.54362408599289e-12 9.40193113444259 -1.60313066409647 3.69133003263924e-13 222.584956639212 32.2078236549939 6.91089714795741 1.41351524441519e-10 -140.145359112544 83.6760088297122 -1.67485711941342 0.0961176717304124 PRPF40B other 4.74599416624901e-09 1 1.83361197505538e-06 6.91089714795741 -1.67485711941342 0.697527573615747 -8.09701746069367 15.7961818795244 -0.512593329353171 0.608965517342793 -56.0294550446393 70.0052645705247 -0.800360592712196 0.424726915975444 CD69 other 1 1 1 -0.512593329353171 -0.800360592712196 5.85434382059165e-14 156.784226494853 34.8584086348116 4.49774480921884 1.33933140768729e-05 -267.398356855526 70.231791965327 -3.80736913259367 0.000201890064978438 PRDM4 other 7.68968060834714e-10 1 0.13429774001968 4.49774480921884 -3.80736913259367 0.555003244182954 -11.011989412973 10.4854346532865 -1.05021773317919 0.295252691084768 -27.11421051592 46.4691805044199 -0.583488028443735 0.560412883989743 CLEC2B other 1 1 1 -1.05021773317919 -0.583488028443735 2.23881855480205e-10 61.7104812649074 22.2636638525376 2.77180259608859 0.00625341379569938 -187.827867328358 44.6554256513614 -4.20616004860837 4.36573530345485e-05 COQ5 other 2.60911914376631e-06 0.628709541050533 1 2.77180259608859 -4.20616004860837 0.284142617291058 -15.4808309196798 31.6107165366422 -0.489733628838654 0.625014808679172 65.2005910423179 63.2791008329412 1.03036532099989 0.304443656601079 SELPLG other 1 1 1 -0.489733628838654 1.03036532099989 0.0425137584151035 38.7967236600331 87.5730862069472 0.443021084906738 0.658368168621547 -331.620691325728 175.305932907837 -1.8916683869454 0.0604004034839788 CORO1C other 1 1 1 0.443021084906738 -1.8916683869454 0.558461052048734 -19.4979211210085 24.8000290599559 -0.786205575560853 0.432971015410166 -62.6097069462039 63.1485372702648 -0.991467255658594 0.323033161804091 ASIC1 other 1 1 1 -0.786205575560853 -0.991467255658594 4.68180796972106e-33 168.143177167998 10.6407427226273 15.8018271422393 1.17205698495606e-33 -20.5904117233181 96.0670677432573 -0.214333717131314 0.830579872131103 CAPRIN2 other 6.80079425681681e-29 1 1.70417085612611e-29 15.8018271422393 -0.214333717131314 0.870579687978901 -0.253700827892696 8.66094997084288 -0.0292924943276178 0.976670511414523 -42.6632914979934 81.1968945845451 -0.525430088383132 0.600065279202543 TSPAN11 other 1 1 1 -0.0292924943276178 -0.525430088383132 8.12988038949053e-05 74.7119467443839 57.8494519090963 1.29148927567689 0.198469120534326 -342.834051948189 115.235137119937 -2.97508260515513 0.00340185986009022 KCTD10 essential 0.603399722507987 1 1 1.29148927567689 -2.97508260515513 0.0271182815818664 130.116793267001 118.263974314014 1.10022341141281 0.272962832820125 -565.599399094184 297.003193043849 -1.90435460742902 0.0587408989787293 SLC11A2 other 1 1 1 1.10022341141281 -1.90435460742902 1.81976852874906e-08 667.069342925292 245.669790021874 2.71530880075201 0.0073679195074847 -1709.5107268344 492.753084836797 -3.46930497127298 0.000674776566782098 MLEC other 0.000191093893203938 1 1 2.71530880075201 -3.46930497127298 8.98498361839501e-06 40.2827988800533 26.588635192094 1.51503823302789 0.131812537806801 -173.402280420138 52.964114975671 -3.27395785806655 0.00130968565569882 MVK essential 0.0745753640326786 1 1 1.51503823302789 -3.27395785806655 5.4062112876285e-09 238.478447373928 47.4689976027489 5.02387788698781 1.38766240864602e-06 -249.139516635279 120.075652268055 -2.07485457650569 0.0396636287350352 CSRNP2 other 5.85600806675919e-05 1 0.0150325468728623 5.02387788698781 -2.07485457650569 1.1410875745087e-12 261.888416833455 45.6122438291772 5.74162538055036 4.75796731214197e-08 -194.130113909411 99.0097193331044 -1.9607177478838 0.0516929089612875 CAMKK2 other 1.44621439193233e-08 1 0.000562058678583331 5.74162538055036 -1.9607177478838 0.0628599091435011 5.16783890654945 11.288607532601 0.457792415196024 0.647746836909744 67.7797503405956 28.9708972472478 2.33958064060424 0.0205893175900863 BIN2 other 1 1 1 0.457792415196024 2.33958064060424 0.0853311809091313 4.67062699996831 5.57103937474499 0.83837623211595 0.403335014760594 -23.4769191775179 14.4764437159986 -1.62173249439518 0.107246836629804 IL23A other 1 1 1 0.83837623211595 -1.62173249439518 0.000147010541789002 1477.44667923738 766.902809322274 1.92651097541686 0.0561577547015427 -5703.64130176689 1936.65424158854 -2.94510046206724 0.00380769642817702 ATP5B essential 1 1 1 1.92651097541686 -2.94510046206724 9.83417824226873e-05 282.37439376065 259.520800739738 1.08806073715775 0.278492748993893 -2384.9190315463 655.393847793987 -3.63890970227105 0.000387811398763738 PTGES3 other 0.721927024764948 1 1 1.08806073715775 -3.63890970227105 2.94162912149043e-06 172.931878653393 45.6281115463409 3.79002927784465 0.000215223821941757 -123.9759351147 101.236416824868 -1.22461796854357 0.222577116454976 BCL7A other 0.0256098231316957 1 1 3.79002927784465 -1.22461796854357 2.36307475920925e-12 187.47375592417 42.9182783631217 4.36815648423728 2.30826981531937e-05 -345.063154351572 96.2896207916391 -3.58359656538947 0.000455833549799165 RSRC2 essential 2.96636774523537e-08 1 0.226118111108686 4.36815648423728 -3.58359656538947 1.74643893811804e-14 25.5746526921206 2.93238273686089 8.72145793611453 8.19289059136311e-15 2.41208934499601 9.73069325582614 0.247884634895031 0.804594815534163 CYP27B1 other 2.31927090982075e-10 1 1.14069615703549e-10 8.72145793611453 0.247884634895031 0.877637470135408 -0.652640167326298 3.06961361542074 -0.212613132821553 0.831921284797163 -3.29299681755485 6.50356868833601 -0.506336901378585 0.613373599314287 LIN7A other 1 1 1 -0.212613132821553 -0.506336901378585 0.00294077844147709 994.781087756434 1534.4427624346 0.648301202306224 0.517808467724146 -11324.0698119865 3823.31364741004 -2.96184693600996 0.00357083247959141 KRT18 other 1 1 1 0.648301202306224 -2.96184693600996 0.0134971197471637 85.7408470893698 34.6830832921324 2.47212297612593 0.0145640538110458 -5.45361112864107 73.4828036273044 -0.0742161547931827 0.94093860713271 ACSS3 other 1 1 1 2.47212297612593 -0.0742161547931827 0.820123792856781 97.26799571241 160.342172106503 0.606627654063477 0.545066681773606 147.635731336022 405.169846255862 0.364379858719276 0.716116410877912 TNS2 other 1 1 1 0.606627654063477 0.364379858719276 0.513588368094825 -4.08268204916156 4.73117328761012 -0.862932258231418 0.389728109233156 -15.6524073308341 15.8752537573765 -0.985962654207097 0.32594170998628 GLI1 og 1 1 1 -0.862932258231418 -0.985962654207097 0.00360292058786058 123.76072374624 57.3502566582741 2.15798029438085 0.0325315417733237 -266.440879091277 142.723351358003 -1.86683451976226 0.0638896763829607 PPM1H other 1 1 1 2.15798029438085 -1.86683451976226 2.11197384178868e-15 155.44960362401 76.2636358757394 2.03831881130468 0.0432069218154961 -980.300433769953 153.035482821402 -6.40570680535574 1.67941143886715e-09 METAP2 essential 2.85200947595143e-11 2.45613922934321e-05 1 2.03831881130468 -6.40570680535574 4.64364833321165e-14 616.841813438316 123.143030070354 5.00914922335353 1.48209634058865e-06 -796.980187940337 245.370936405942 -3.24806270707551 0.00142639664424037 LTA4H other 6.11336303067313e-10 1 0.0160229435381039 5.00914922335353 -3.24806270707551 0.013956459276014 65.2452690912712 56.7961781541034 1.14876161058308 0.252435431516486 -189.383085745196 113.17028182585 -1.67343478066641 0.0962717793646428 ELK3 other 1 1 1 1.14876161058308 -1.67343478066641 0.283120565322736 39.4474746471633 25.4919480587524 1.54744841611347 0.12411367501685 93.1409039396205 100.949151355817 0.922651678480438 0.357847065446275 SLC6A12 other 1 1 1 1.54744841611347 0.922651678480438 0.179745471703308 24.4172243615169 18.5237140185634 1.31816029642043 0.189572362749781 -56.5937755732165 76.2807066335832 -0.741914673720401 0.4593644001015 WNT5B other 1 1 1 1.31816029642043 -0.741914673720401 9.13850415541311e-07 113.52882442018 21.1383542588468 5.37075039191691 2.79894734334281e-07 46.1176950665495 87.2915986765252 0.528317681950665 0.59802963152163 MAGOHB other 0.00836264515261854 1 0.00316672902425806 5.37075039191691 0.528317681950665 0.0675190465600619 -10.2478067122796 29.269703114257 -0.350116523979637 0.726729638403798 -125.730407540082 58.30475727119 -2.15643479922707 0.0326017724160289 TRPV4 other 1 1 1 -0.350116523979637 -2.15643479922707 4.01894156620798e-05 392.937165124209 103.403604572755 3.80003353604311 0.000209306889534686 -593.466457069477 490.186003982709 -1.21069645450426 0.22790335357312 FOXM1 other 0.309016417025731 1 1 3.80003353604311 -1.21069645450426 3.88666880907648e-21 52.1363980936496 5.09841422258741 10.2260027956674 4.17250550235095e-19 -27.2915394362586 23.5835772613889 -1.15722645185556 0.248948704432971 PRR4 other 5.52606571274493e-17 1 5.95708610570645e-15 10.2260027956674 -1.15722645185556 8.31245207437414e-10 69.1536422294899 11.4397828752051 6.04501352725631 1.07147513855789e-08 -57.6043969596154 52.7733475338234 -1.09154335761429 0.276727668359492 PARP11 other 9.42299567151053e-06 1 0.000130237803091711 6.04501352725631 -1.09154335761429 0.000421655106801229 -10.3044483020501 231.056352774972 -0.044597121776979 0.964486589339079 -1586.47168637662 456.626742535432 -3.47432933421222 0.000666370422939565 ARPC3 essential 1 1 1 -0.044597121776979 -3.47432933421222 3.69285141220346e-09 52.1540414451559 20.7937541643573 2.50815899009489 0.0131789784611844 -162.170236157824 41.093802940793 -3.94634286808342 0.000120617574568687 GPN3 essential 4.0403487300918e-05 1 1 2.50815899009489 -3.94634286808342 0.00047099843303961 -6.92277313659516 86.0896343295218 -0.0804135502550417 0.936013438371168 -589.791877328125 170.135245440497 -3.46660608624095 0.000684362090105878 VPS29 essential 1 1 1 -0.0804135502550417 -3.46660608624095 3.24303689301486e-08 89.0486080544176 16.5300382229878 5.38707816964273 2.61220285853505e-07 -79.4802158936005 75.1066425574534 -1.05823151171751 0.291596309142529 RAD51AP1 other 0.000334519255514483 1 0.00296119316043534 5.38707816964273 -1.05823151171751 0.0574212872299717 13.1161568751319 19.527914279548 0.671661944402772 0.502805248502966 -63.2367837794195 38.5042247886956 -1.64233364329374 0.102561296819772 CUX2 other 1 1 1 0.671661944402772 -1.64233364329374 0.869729591338968 -26.4533965300933 51.9827278391967 -0.508888194785087 0.611558911099308 -14.2538121239115 102.497102824048 -0.139065512401657 0.889580073334352 SH2B3 other 1 1 1 -0.508888194785087 -0.139065512401657 0.00020735956906952 21.0462385378028 6.88496146909667 3.05684187664221 0.0026350475978577 -53.1724201451571 31.282827849857 -1.69973189125868 0.0911872408281365 AKAP3 other 1 1 1 3.05684187664221 -1.69973189125868 6.12560597778514e-06 168.559704853112 39.8920412284295 4.22539683762751 4.07014010648466e-05 -173.621697185975 158.418977438901 -1.09596526876294 0.274804918962475 MANSC1 other 0.0516204815747954 1 0.388209963356507 4.22539683762751 -1.09596526876294 1.13855048306496e-13 326.099928962282 43.8533042162931 7.43615412316239 6.90526947610574e-12 -244.869295748547 174.234080408844 -1.40540412744715 0.161928443843462 DUSP16 other 1.48273429409549e-09 1 9.23786950513427e-08 7.43615412316239 -1.40540412744715 5.12730393640893e-13 156.280955897528 22.6030766358307 6.91414529160995 1.19828218561769e-10 -158.716197097298 88.5561529030047 -1.79226617117322 0.0750663601146764 CREBL2 other 6.56705088175256e-09 1 1.55704787199163e-06 6.91414529160995 -1.79226617117322 4.11842410100412e-12 182.768158792734 40.0767825325369 4.56044989750241 1.03503389154721e-05 -249.240838473114 78.6827324951835 -3.16766882096235 0.00185331308663265 ACAD10 other 5.12908537539054e-08 1 0.104952436602887 4.56044989750241 -3.16766882096235 0.58434575322685 145.203959220873 140.25316633077 1.03529897413102 0.302152285481488 128.465123672664 275.358990184582 0.466536878227762 0.641490553017369 ALDH2 other 1 1 1 1.03529897413102 0.466536878227762 4.66351355935893e-08 234.761226794243 45.1697537136022 5.19731031262073 6.374391148711e-07 -218.565518419743 177.167454558704 -1.23366630154593 0.219219066878465 CDKN1B ts 0.000475305301969862 1 0.00705198892781898 5.19731031262073 -1.23366630154593 6.9685814268403e-12 158.043002345582 31.5447121590413 5.01012662752367 1.48438134082326e-06 -151.49477311557 62.7909103535767 -2.41268636276335 0.0170184444472005 NAA25 essential 8.61177292728925e-08 1 0.0160446779129586 5.01012662752367 -2.41268636276335 4.24820416984178e-09 1960.57569906482 355.027446380523 5.5223214966976 1.42644861068877e-07 -2587.64100714961 1588.31358074818 -1.62917514432553 0.105360396747439 SCNN1A other 4.6288432634596e-05 1 0.0016439820238188 5.5223214966976 -1.62917514432553 1.60122520766557e-09 535.355208672592 103.071221932481 5.19403184162588 6.55933209708366e-07 -1127.43376359523 461.117649490689 -2.44500240847536 0.0156354253465051 LTBR other 1.78824831192091e-05 1 0.00724937383369687 5.19403184162588 -2.44500240847536 2.41537238485436e-11 52.4565465980561 14.4530083978825 3.62945520779891 0.00039463764359999 -129.962200622578 32.064513503284 -4.05314743382174 8.26297309257362e-05 OGFOD2 other 2.92839747939743e-07 1 1 3.62945520779891 -4.05314743382174 0.000954177174536885 245.00740732754 239.47021124404 1.02312269260855 0.307864794686145 -1405.24791365665 520.141446563253 -2.70166494699007 0.00767807331990578 CDK2AP1 other 1 1 1 1.02312269260855 -2.70166494699007 0.339199807219075 339.479216929758 454.06057242211 0.747651827858258 0.455825306517887 -652.985555249191 907.584369164386 -0.719476422726843 0.472952172021833 OAS3 other 1 1 1 0.747651827858258 -0.719476422726843 0.61470659237509 164.92293194144 416.354234536186 0.396112056180147 0.692574221985841 -484.773669035919 831.133002293304 -0.583268463288435 0.560571355632882 OAS2 other 1 1 1 0.396112056180147 -0.583268463288435 0.500268715283435 -385.434150286597 433.642003110168 -0.888830296701394 0.375526975153066 -1718.86537096578 1669.49512849558 -1.02957195958678 0.304879374695648 MGP other 1 1 1 -0.888830296701394 -1.02957195958678 0.271978780143056 79.5143677583888 57.6641039275666 1.37892314876286 0.169917957736817 -5.50154286899996 114.962731127315 -0.0478550119247543 0.961893798590018 RASAL1 other 1 1 1 1.37892314876286 -0.0478550119247543 0.426260453039446 -91.272834287396 87.1889370916583 -1.04683962589708 0.296880189640654 -371.725751404666 337.046113743698 -1.10289285722885 0.271863835393594 ARHGDIB other 1 1 1 -1.04683962589708 -1.10289285722885 3.01730109804126e-13 98.9136878285483 20.5488906820118 4.81357798623826 3.5462430271184e-06 -188.147540099744 48.6853441090161 -3.86456219100442 0.000164415589111133 GTF2H3 essential 3.88688727449675e-09 1 0.037377401505828 4.81357798623826 -3.86456219100442 2.33579386161673e-15 231.217886507616 39.6953735669694 5.82480691654235 3.2938310776948e-08 -343.012131014961 94.0480414028192 -3.6472012165123 0.000363645025270793 EIF2B1 essential 3.15098591932096e-11 1 0.000391965898245681 5.82480691654235 -3.6472012165123 8.58170261472632e-08 70.1665318776115 19.9876027265772 3.51050262692644 0.000588865515282716 -129.192950532417 47.355515765606 -2.72815000414901 0.00711957341374193 DDX55 essential 0.000858942614707957 1 1 3.51050262692644 -2.72815000414901 6.8047607275176e-14 1662.0725883637 200.694760076412 8.28159433624916 7.87934047979157e-14 216.855172529595 657.589107103445 0.329773060695608 0.742054015419445 SLC38A1 other 8.91899988555732e-10 1 1.08435483682892e-09 8.28159433624916 0.329773060695608 0.567320621854976 -4.77603961106526 4.74542025767121 -1.00645240078464 0.315829649696423 -0.126421728678558 16.5514956524958 -0.00763808487962803 0.993915966257155 ENDOU other 1 1 1 -1.00645240078464 -0.00763808487962803 1.47792010161155e-07 160.026397225603 52.1264208661699 3.0699671024116 0.00252836195134561 -291.164413448772 101.037961200661 -2.88173286543777 0.00451627692687359 C12orf49 other 0.00145028299571141 1 1 3.0699671024116 -2.88173286543777 0.73320619204491 -34.0507520341909 43.3050777380103 -0.786299293588463 0.432984196651814 -46.504095778198 144.345858137077 -0.322171320870431 0.747790151836 VDR other 1 1 1 -0.786299293588463 -0.322171320870431 1.41483571739287e-05 240.106527813978 97.2324472265287 2.46940743201276 0.0146705373391661 -423.846037586405 184.940302009216 -2.29179920753716 0.02332771137014 FZD10 other 0.114997847109693 1 1 2.46940743201276 -2.29179920753716 2.44023330014507e-05 58.967364596862 38.6738112600792 1.52473631833981 0.129362674319884 -235.552808101372 74.8866659682953 -3.14545727274196 0.0019883863128371 RFC5 essential 0.193559305367507 1 1 1.52473631833981 -3.14545727274196 0.0961921003857581 -3.84454199351371 14.994439806407 -0.25639784100977 0.797994969222866 -57.2437382650449 29.2317632461417 -1.958271821752 0.0520533223548823 STX2 other 1 1 1 -0.25639784100977 -1.958271821752 0.0536199764519557 9.60142414009146 11.9165328809963 0.80572295951981 0.421695261202719 -35.3868862979997 23.1812699503875 -1.52652923561714 0.129012364409392 ADGRD1 other 1 1 1 0.80572295951981 -1.52652923561714 2.62327624482753e-07 360.020714360973 125.071254696566 2.87852484757121 0.00460913500943612 -1409.05683700348 362.51233227408 -3.88692111014351 0.000154837194079636 COPZ1 essential 0.00251755821216098 1 1 2.87852484757121 -3.88692111014351 0.00123954835407906 11.5052457860064 5.36143250216097 2.14592756345792 0.0334984424247054 -36.5547422067031 16.413694723439 -2.22708797882675 0.0274408987978178 TBC1D30 other 1 1 1 2.14592756345792 -2.22708797882675 1.67420431191222e-63 2079.15472419524 70.9845688385719 29.2902353034433 3.69900139620551e-64 570.180851677943 445.470856652766 1.27995096236427 0.202525316726759 CAND1 other 2.44601249970375e-59 1 5.40424103985625e-60 29.2902353034433 1.27995096236427 1.06195641615967e-05 656.389855038813 230.105265116467 2.85256338965813 0.0050147210252501 -1805.95013428065 631.71510944473 -2.85880471636662 0.0049226723673567 RAB5B other 0.0875264478198799 1 1 2.85256338965813 -2.85880471636662 2.6210493400235e-59 103.828131583305 3.90538455766016 26.585891875783 3.14736908955801e-59 -39.9063649480533 32.564144568834 -1.2254694688417 0.222281467979947 MDM1 other 3.82778045617032e-55 1 4.59673255529947e-55 26.585891875783 -1.2254694688417 2.89706082062291e-63 492.294350094329 17.102842153477 28.7843590952073 2.06602426550966e-63 -93.4242270026511 142.684861875804 -0.654759206929529 0.513612377898387 NUP107 essential 4.23202644676594e-59 1 3.01825484948307e-59 28.7843590952073 -0.654759206929529 3.12084137000699e-50 752.09912133569 33.954488909742 22.1502118124918 4.96851402247469e-50 -2.15912526743311 183.379259897049 -0.0117740974014469 0.990620890480033 CNOT2 other 4.5529954747032e-46 1 7.24906195879058e-46 22.1502118124918 -0.0117740974014469 2.42639307611262e-06 380.516442566154 83.1815202310243 4.57453099569863 1.08714093724732e-05 -185.971328980757 211.513003301336 -0.879243006709185 0.380867327344284 TIMELESS essential 0.0213328479251822 1 0.110040405668174 4.57453099569863 -0.879243006709185 1.89950946146149e-51 515.412090212282 22.1553903613393 23.2635075169637 8.71149245779823e-52 -33.7150741878178 184.938049450202 -0.182304692236393 0.855588135192316 CPSF6 essential 2.7717642061646e-47 1 1.27118097944192e-47 23.2635075169637 -0.182304692236393 5.05212711223754e-12 151.421930928526 36.7343213428411 4.12208325601843 6.13516191247042e-05 -302.827014857068 79.4534818124141 -3.8113750077313 0.000199818198140277 KRR1 essential 6.27171059713168e-08 1 0.574373858245481 4.12208325601843 -3.8113750077313 2.42571885459613e-09 348.400551184812 66.6510480723794 5.22723289822041 5.63643631323516e-07 -671.930511904203 296.534461705746 -2.26594409310499 0.0248760712246024 MRPL51 other 2.68211733752694e-05 1 0.00625644430769103 5.22723289822041 -2.26594409310499 6.35368242191016e-09 17688.3710948825 3715.83039320211 4.76027407689069 4.51172896953002e-06 -44479.4159421229 16448.0782592494 -2.70423177960686 0.00763762777301399 GAPDH essential 6.85435259675668e-05 1 0.0472107319371621 4.76027407689069 -2.70423177960686 5.93669096459851e-17 419.966829058605 46.566562383703 9.01863499388525 8.74965315363201e-16 -177.586127429909 210.222645657931 -0.844752604430987 0.399603341823659 NOP2 essential 8.18907151656719e-13 1 1.22757633745457e-11 9.01863499388525 -0.844752604430987 3.22188499108249e-09 1101.13182195476 178.818961776508 6.15780234386428 6.96348865258499e-09 -396.885203905176 779.329740797488 -0.509264799132449 0.61134613011225 CHD4 essential 3.53988503970233e-05 1 8.53862978579972e-05 6.15780234386428 -0.509264799132449 2.23086002974022e-07 34.6749192403448 6.77179076813251 5.12049477422163 9.47234443007793e-07 -32.5027057056439 29.6892679764617 -1.09476278537459 0.275423337349404 ACRBP other 0.0021545646167231 1 0.0103655865098343 5.12049477422163 -1.09476278537459 8.62486852930125e-07 50.0661898088538 15.3915332441254 3.25283966286874 0.00140416339804015 -61.4802664807609 30.9995357501989 -1.98326410357182 0.049116073671119 UHRF1BP1L other 0.00790727946766338 1 1 3.25283966286874 -1.98326410357182 2.02883562951967e-08 206.969254747844 43.4110549576696 4.76766240649212 4.46432097213315e-06 -475.858089339726 190.325201694704 -2.50023688456685 0.0135166111881698 COPS7A other 0.000212317648629234 1 0.0467280476153176 4.76766240649212 -2.50023688456685 9.17585948176449e-08 179.895315940001 34.2563814755064 5.25143953305832 5.2341605430018e-07 -179.406930927347 150.188764590357 -1.19454295676966 0.23420265215141 ING4 other 0.000915842534874914 1 0.00582457385225241 5.25143953305832 -1.19454295676966 0.00012554170007143 13.9962808668147 3.64567121370207 3.83915061078748 0.000187372073884051 -13.0845210620617 16.1839240207931 -0.808488784626693 0.420200846967434 GNB3 other 0.909424075317439 1 1 3.83915061078748 -0.808488784626693 0.000281513514606146 110.48700205177 30.4531580495363 3.62809669434111 0.000400093520824072 -109.55015162084 135.326898226024 -0.809522371804225 0.41959833660376 CDCA3 other 1 1 1 3.62809669434111 -0.809522371804225 0.000223303220008098 10.7015786278083 48.4334980397561 0.220954072303926 0.825417125031853 -330.377366561792 96.9939238422964 -3.4061655975374 0.000837962550677368 CHPT1 other 1 1 1 0.220954072303926 -3.4061655975374 1.579906545981e-17 635.4354488417 69.0977609121688 9.19618002744564 5.1631102450232e-16 -394.366312741312 307.223022000174 -1.28364830921131 0.201416257548297 USP5 essential 2.19259430451244e-13 1 7.2552025163066e-12 9.19618002744564 -1.28364830921131 1.85153292205548e-06 2175.16098493816 490.466646428238 4.43488053831692 1.88400196709023e-05 -3336.62919561754 2159.15788045138 -1.54533821997306 0.124588273529382 TPI1 essential 0.0164897522038261 1 0.186195914407528 4.43488053831692 -1.54533821997306 0.00187512580376449 121.491499696418 54.2106283951536 2.24110111417338 0.0264310042619445 -125.541452779158 108.563324451323 -1.15638917114635 0.249289828438271 GNPTAB other 1 1 1 2.24110111417338 -1.15638917114635 5.60452321875908e-05 225.779260147841 51.978098876156 4.34373832497774 2.70693432324428e-05 -10.9076069015927 231.944487926445 -0.0470267993824962 0.962560351442331 ENO2 other 0.424150317195687 1 0.263547125711063 4.34373832497774 -0.0470267993824962 3.22444560973857e-05 2753.07606329327 640.387496821063 4.299078412617 3.22081970411362e-05 -1502.42378202758 2877.82728825072 -0.522068780208426 0.602459433652842 ATN1 other 0.251667979840095 1 0.311163391614416 4.299078412617 -0.522068780208426 0.0587156462840915 245.542497593658 146.463397431741 1.67647686657066 0.0958764740464415 -754.108900738596 659.202702892618 -1.14397119039337 0.254587785856303 C12orf57 other 1 1 1 1.67647686657066 -1.14397119039337 5.40427670138906e-09 170.021995415348 28.5425199864836 5.95679692948844 1.92986884838784e-08 -110.842790088418 123.646776391204 -0.896447067392396 0.371531265110327 PTPN6 other 5.85445295061477e-05 1 0.000232086027707122 5.95679692948844 -0.896447067392396 1.38018202482586e-10 303.196275954455 47.2970637537529 6.41046720221393 1.94436542431406e-09 -294.803052977387 200.719210687219 -1.46873362030493 0.144086198351944 LPCAT3 other 1.62378415220763e-06 1 2.4318178361896e-05 6.41046720221393 -1.46873362030493 7.37482968094536e-08 44.4408252926347 16.2209876386124 2.73971143328214 0.00686610968269013 -99.5480070854836 33.2735819363548 -2.99180314508662 0.00322464413409519 NT5DC3 other 0.00074235035568396 1 1 2.73971143328214 -2.99180314508662 0.478887641794458 -7.65136376647629 6.58365956983591 -1.16217487938353 0.24699801726432 0.223196070680543 40.0874935448911 0.00556772327086506 0.995564971457838 SLCO1B3 other 1 1 1 -1.16217487938353 0.00556772327086506 1.16593506266602e-14 286.897796667438 50.8028622243389 5.64727623810907 7.58505949300223e-08 -312.488549428272 98.2601272039915 -3.18021722869882 0.0017775748253296 SUDS3 other 1.55290890996487e-10 1 0.000886541753542101 5.64727623810907 -3.18021722869882 3.38168333979607e-17 304.819253700402 33.3219120199188 9.14771197757771 3.73597890002123e-16 -227.59790787346 203.215469848567 -1.11998317865792 0.264499177944275 GOLT1B other 4.67416271226613e-13 1 5.25614871443987e-12 9.14771197757771 -1.11998317865792 3.78259343242025e-17 2298.22289066711 255.463764541326 8.99627739688822 9.18526640810401e-16 -2255.32450350346 1557.95948652397 -1.44761434620833 0.149797950290779 LDHB other 5.22640934557506e-13 1 1.28841731906475e-11 8.99627739688822 -1.44761434620833 1.20951914542268e-07 102.349946816593 63.3493385115234 1.61564349717677 0.108205057861384 -507.702628779821 125.864135751758 -4.03373546997663 8.59354340885744e-05 PRKAB1 other 0.0011950049156776 1 1 1.61564349717677 -4.03373546997663 1.84249026761112e-15 161.727526798287 19.4987361642342 8.29425689111777 5.78725767809185e-14 -199.675200089088 120.887515560387 -1.6517437649659 0.10067870433156 CMAS other 2.491231090837e-11 1 7.97426235464275e-10 8.29425689111777 -1.6517437649659 0.000255570607180682 21.6984888755624 9.24995494153557 2.34579400793927 0.0202447443233446 -30.2589705189774 18.9741303373006 -1.59474874374044 0.112792409312289 HCFC2 other 1 1 1 2.34579400793927 -1.59474874374044 0.703737181941883 -0.555943259827641 2.5904543454895 -0.214612259349658 0.830361122968502 -13.8304435766952 16.4801419417807 -0.839218717020398 0.402682066922519 ST8SIA1 other 1 1 1 -0.214612259349658 -0.839218717020398 0.997074743047258 -0.101430738621382 2.40143031811951 -0.0422376355691261 0.966363973370783 0.54227493604824 11.0001444182126 0.0492970742411718 0.960746429033434 CLEC4A other 1 1 1 -0.0422376355691261 0.0492970742411718 2.37163545526601e-22 249.121113819097 22.8924664516903 10.8822312503904 1.15884976672874e-20 -141.139608580369 116.770635291239 -1.20869093696674 0.228696239072008 C2CD5 other 3.38622110302882e-18 1 1.66248587534906e-16 10.8822312503904 -1.20869093696674 2.19073056840695e-06 86.0576953331214 46.8911738458157 1.83526425710925 0.0683832189774089 -301.784115341721 91.7595303026623 -3.28885854522476 0.00124497407766022 RAB35 other 0.0193660582247174 1 1 1.83526425710925 -3.28885854522476 8.62057543839299e-24 505.517640816619 45.0156084365858 11.2298302382994 1.09260071428487e-21 -318.675203917228 196.595704213753 -1.62096727999072 0.10709729604244 PHC1 other 1.23739739842693e-19 1 1.57083204692736e-17 11.2298302382994 -1.62096727999072 0.000390901483721439 -279.843349216356 274.642122030832 -1.01893819909002 0.309820087077312 -2154.17536096043 553.749702450512 -3.89016075571246 0.00014833230948428 COX6A1 other 1 1 1 -1.01893819909002 -3.89016075571246 1.89925939318455e-13 126.132526872774 23.0050015809509 5.48283061094059 1.65107904948302e-07 -109.591800059902 46.6221365417333 -2.35063873492375 0.0199922379969819 RIC8B other 2.46011069199195e-09 1 0.0018954387488065 5.48283061094059 -2.35063873492375 1.60018891716107e-11 299.979888764423 134.982144008078 2.22236719507486 0.0277063896346812 -1388.45876510874 272.158988315033 -5.10164581998501 9.72099558813425e-07 SRSF9 other 1.95335061117852e-07 0.0141858488617643 1 2.22236719507486 -5.10164581998501 2.18546002492746e-43 98.8020311235712 5.01803476867821 19.689387514865 2.64974605763332e-43 -118.688457274679 62.1220304207543 -1.91056951086111 0.0579807270392247 FGFR1OP2 other 3.18508944032928e-39 1 3.86279980281786e-39 19.689387514865 -1.91056951086111 0.643955041536415 -1.95345938893541 2.1342010923276 -0.915311774489312 0.361458974350278 -0.876930266975627 9.39218312920081 -0.093368097162544 0.92573249491446 KLRB1 other 1 1 1 -0.915311774489312 -0.093368097162544 0.0550239225379316 -832.857639528289 462.586070128813 -1.80043821746809 0.0737743274358456 -2118.59191520392 900.632032309791 -2.3523390676773 0.0199374807273838 COL12A1 other 1 1 1 -1.80043821746809 -2.3523390676773 0.0546810624216333 57.5829745868628 50.021090239805 1.15117392105621 0.251555419357364 -267.179558394667 160.889588777526 -1.66063920247888 0.0989468325483289 BTN3A3 other 1 1 1 1.15117392105621 -1.66063920247888 1.20415842623927e-10 138.51885905447 27.4245320181902 5.05091058482213 1.22931521975327e-06 -232.107779309743 79.7761282959729 -2.90948914503112 0.00415668898384115 TDP2 other 1.42102735880497e-06 1 0.0133540512321798 5.05091058482213 -2.90948914503112 2.46697237271998e-05 21.6679503799095 38.1443987338033 0.568050646993355 0.570812088860732 -265.1153638712 79.1242928333511 -3.35061906246135 0.00101000244757082 FRK other 0.195630909156695 1 1 0.568050646993355 -3.35061906246135 0.00347803467425073 17.8457860131499 70.0452294682843 0.254775180959758 0.799232299608892 -367.277346084878 145.483648546724 -2.52452663755488 0.0125847472601207 DSE other 1 1 1 0.254775180959758 -2.52452663755488 1.68003549784323e-09 58.7262098396067 33.9781549913057 1.72835193242934 0.0859038022140755 -288.247432410994 70.5724857573563 -4.08441660113903 7.04373664586132e-05 RWDD1 other 1.87458360849348e-05 1 1 1.72835193242934 -4.08441660113903 0.745114695539865 -4.65998794598638 20.5347975369524 -0.226931282745823 0.820774282437324 18.5043150460266 42.8740339072444 0.431597248023353 0.666630042947293 RSPH4A other 1 1 1 -0.226931282745823 0.431597248023353 0.0411759362176303 9.10617806714527 8.61377223822431 1.0571649464721 0.292091824526208 -37.4774437425228 23.9341319355048 -1.5658576564846 0.119434495225864 MAK other 1 1 1 1.0571649464721 -1.5658576564846 1.45423889264536e-06 401.348891259014 129.486402123968 3.09954469871491 0.00230488598743915 -898.255157981355 359.789479751529 -2.49661318224672 0.0135910622697138 TMEM14C other 0.0130750618837744 1 1 3.09954469871491 -2.49661318224672 2.85143176318292e-15 149.187061239434 21.5108551275493 6.93543145332084 1.04987465528424e-10 -124.135955927102 59.7698233050133 -2.07690016571774 0.0394716874461663 PAK1IP1 essential 3.84030829865475e-11 1 1.36746173850772e-06 6.93543145332084 -2.07690016571774 0.0853079256802192 24.9569582521253 24.6145838559695 1.01390941232885 0.312237196812149 -88.1298043064421 68.1959494451581 -1.29230262242062 0.198213549359821 GCNT2 other 1 1 1 1.01390941232885 -1.29230262242062 1.35136606982179e-06 757.345569620253 154.697332185679 4.89566018314546 2.45098561064307e-06 82.4099318403122 431.47042286271 0.190997870244594 0.848778833888471 NEDD9 other 0.0121866192176529 1 0.0261250556238445 4.89566018314546 0.190997870244594 5.49814044744042e-10 77.6494513118774 11.7022156614577 6.63544866700949 5.0413149422647e-10 58.5110775922435 24.3837078821508 2.39959721774203 0.0175922420401989 CEP85L other 6.28932285782709e-06 1 6.42465176242213e-06 6.63544866700949 2.39959721774203 0.451010870987429 -1.61624639611292 6.35265192716876 -0.254420738715531 0.799509939183703 -21.4701078604984 17.6290378284728 -1.21788313516588 0.225131084875509 ADTRP other 1 1 1 -0.254420738715531 -1.21788313516588 2.75660274826069e-15 163.962672557693 25.8044118443185 6.35405579274202 2.25242611271579e-09 -66.0074545913843 53.6981984941394 -1.22923033625771 0.220860326520541 ASF1A other 3.71424654300646e-11 1 2.81057730344676e-05 6.35405579274202 -1.22923033625771 6.65451413022259e-16 85.6975565781197 14.8763663882004 5.76065111209503 4.41834676403962e-08 -69.5481923235044 30.9572673078 -2.24658693650201 0.0260883264055891 MCM9 other 9.06078643971108e-12 1 0.000522778789121168 5.76065111209503 -2.24658693650201 0.000293873131152129 16.9765768058767 4.7713925849043 3.55799203351807 0.00049793681847377 5.19541010032455 9.69313781375129 0.535988469384395 0.592744876528068 FAM184A other 1 1 1 3.55799203351807 0.535988469384395 3.0724389760533e-12 91.6654185966356 15.5925252076244 5.87880522083833 2.52717321589203e-08 -27.1652311339392 30.9562885469814 -0.877535144198934 0.381580954346273 RNGTT essential 3.84362115904267e-08 1 0.000302300460085004 5.87880522083833 -0.877535144198934 0.705429407798394 21.9835695702029 91.3214999855627 0.240727206338906 0.810086731984092 144.316626038465 185.656059567271 0.777333238542493 0.43815465441998 MAN1A1 other 1 1 1 0.240727206338906 0.777333238542493 7.39529518707442e-08 420.377538488015 110.616376223955 3.80031920081086 0.000208608326511526 -310.200900400525 216.227920383172 -1.43460150683051 0.153454937775591 SERINC1 other 0.00074426250762717 1 1 3.80031920081086 -1.43460150683051 7.96219279429867e-14 251.016649226977 52.9288346919057 4.74253118717093 4.8691978245721e-06 -292.178792925885 102.713989268502 -2.84458616598083 0.00506844570865306 HDDC2 other 1.04177330520604e-09 1 0.0508052101015853 4.74253118717093 -2.84458616598083 7.80763752820889e-07 401.821471249278 171.227726897257 2.34670796915026 0.0202476979012108 -859.417634105015 332.285473605647 -2.5863834033412 0.0106499488426405 TPD52L1 other 0.00718302652595218 1 1 2.34670796915026 -2.5863834033412 4.21130768778527e-12 182.277068632892 37.0076167997394 4.92539332157631 2.21208936025386e-06 -124.164750654087 71.587002717038 -1.73445941220466 0.0849046710082407 HINT3 other 5.24265694052388e-08 1 0.0236516594398343 4.92539332157631 -1.73445941220466 0.0853712178387839 3.91944818837703 180.344940929127 0.0217330642500102 0.982689965540746 -602.352235788472 348.856664998445 -1.72664677566403 0.0863036897734469 NCOA7 other 1 1 1 0.0217330642500102 -1.72664677566403 0.194507434319249 12.2189411297743 12.2987046309942 0.993514479482747 0.322017787304387 -35.7653208273946 35.6115660805256 -1.00431755083507 0.316801012574184 RIPOR2 other 1 1 1 0.993514479482747 -1.00431755083507 1.40046540499053e-07 167.671423716105 47.8847192807009 3.5015643034934 0.000604393019396997 -189.064327034593 98.6175649442995 -1.91714657669127 0.0570588707083735 SASH1 other 0.00137763781888919 1 1 3.5015643034934 -1.91714657669127 7.90199317244748e-08 100.405268376775 17.5516440889338 5.7205620093493 5.32013836953083e-08 61.0262788147202 36.1472391781833 1.6882694280993 0.0933704860879301 UST other 0.000792490895264758 1 0.000627084709616598 5.7205620093493 1.6882694280993 2.27199190482042e-06 103.638953263808 23.3530937083671 4.43791107756639 1.74251528560758e-05 -0.850231749710407 46.1213401455732 -0.0184346713913085 0.985316429388047 FBXO5 essential 0.0200503285600402 1 0.172787815720847 4.43791107756639 -0.0184346713913085 1.48388650076829e-12 73.063285834032 12.9111655657677 5.65892253970859 7.50428614448691e-08 -45.4611623358479 25.5466022405615 -1.77953850409379 0.0771764375907993 MTRF1L other 1.8744454277705e-08 1 0.000877326093151964 5.65892253970859 -1.77953850409379 3.72413702429315e-09 280.46203862295 54.2422055423646 5.17055005080688 7.20195885649203e-07 -227.983759636121 160.4771469016 -1.42066184524027 0.157449828396462 PPARD other 4.07420590457671e-05 1 0.00793439807219727 5.17055005080688 -1.42066184524027 1.07794753410149e-11 80.1540564711895 12.8622941394207 6.23170762558847 4.26949514322631e-09 -47.3949150376901 37.2371184232751 -1.27278686011498 0.205024372012621 FANCE other 1.32415075089028e-07 1 5.27239955237017e-05 6.23170762558847 -1.27278686011498 4.08121692013204e-09 12.4206147355733 2.06307221247604 6.02044594486903 1.2528877371776e-08 1.04310079855357 5.93137818934786 0.175861455003304 0.860636860790647 TULP1 other 4.45260765986405e-05 1 0.000151812407113809 6.02044594486903 0.175861455003304 5.43398885182832e-12 226.238456624505 43.5203701352585 5.19844973563807 6.34129044029047e-07 -366.431582981985 125.994100195906 -2.90832334539654 0.00417503211440707 MAPK14 other 6.7386895751523e-08 1 0.0070166378721814 5.19844973563807 -2.90832334539654 1.83628230973472e-09 248.602516279952 47.9844646798283 5.18089589909417 6.82488195944299e-07 -228.920465322122 139.745228242134 -1.63812724199409 0.103436736957382 KCTD20 other 2.04414946719668e-05 1 0.00753330470683317 5.18089589909417 -1.63812724199409 2.92196184219581e-09 201.750524464471 50.654626864761 3.98286468486106 0.000104713912118847 -452.379950800922 147.521545566224 -3.06653478354349 0.00255851806151146 STK38 other 3.21854096917869e-05 1 0.956247445469308 3.98286468486106 -3.06653478354349 0.00143925924457292 297.277240803838 150.744261085986 1.97206340501593 0.0504052780778476 -850.718543564425 439.197984259075 -1.93698189439458 0.0545899812132352 SRSF3 essential 1 1 1 1.97206340501593 -1.93698189439458 1.75535779602329e-10 193.427171231987 54.2771258491808 3.56369590699148 0.00049646283273301 -369.453589510581 109.466613619154 -3.37503442644119 0.000948748765059429 MRPL18 essential 2.05552397914328e-06 1 1 3.56369590699148 -3.37503442644119 2.10210107615691e-09 680.967816091956 134.83999798727 5.05019153260625 1.26416282269869e-06 -746.933563218391 400.895178184263 -1.86316424807454 0.0643944945755769 MCM3 essential 2.33438324507225e-05 1 0.0137224874403943 5.05019153260625 -1.86316424807454 6.17945137033437e-15 87.7692855870301 14.6381994570745 5.99590720459901 1.41579664845916e-08 -153.09173979759 43.933634567172 -3.4846135837799 0.00064417383271444 RNF8 essential 8.27737511056289e-11 1 0.000171155656832227 5.99590720459901 -3.4846135837799 0.313160505660132 77.0670427790639 55.9288242557571 1.37794855880831 0.170231139036197 5.17719582902274 156.939872859823 0.0329884033590811 0.97372683137036 PHACTR1 other 1 1 1 1.37794855880831 0.0329884033590811 0.408028604545707 2.53278104400505 9.15078659997264 0.276782877224197 0.782322854804778 -29.1829796037998 27.4642599087606 -1.06258022975128 0.289657634172128 MDGA1 other 1 1 1 0.276782877224197 -1.06258022975128 1.91386425989115e-08 149.817655983311 29.3568925715177 5.10332132797548 9.89515096302047e-07 -107.00535748151 87.675926943157 -1.22046451303429 0.22419132984392 ICK other 0.000200649529006988 1 0.010817379032774 5.10332132797548 -1.22046451303429 3.95478607779869e-05 86.6547506163473 35.8255286709105 2.41879893559558 0.0167615004843072 -275.50587223321 106.994853995487 -2.57494507394563 0.0109863349511254 FBXO9 other 0.304518527990499 1 1 2.41879893559558 -2.57494507394563 0.327691496973379 10.0747020083471 20.4982771010692 0.491490185183498 0.623788756074301 -59.4822147475781 56.9217670682936 -1.04498187268523 0.29769034938229 CD83 other 1 1 1 0.491490185183498 -1.04498187268523 2.64961315155277e-09 348.21009745445 62.0858255919658 5.60852810016446 9.82009769736649e-08 28.3349738709083 123.631537048208 0.229188882929276 0.819040676687057 MDN1 essential 2.9249079579991e-05 1 0.00114168455829583 5.60852810016446 0.229188882929276 5.51169819320953e-10 48.177808193918 15.4793131593107 3.11239960701611 0.00221015228701474 -229.512547938349 51.7934681523259 -4.43130294467532 1.76294216258657e-05 SAYSD1 other 6.30428039339306e-06 0.255362172250664 1 3.11239960701611 -4.43130294467532 1.36080767877561e-05 45.4802073942119 11.6896539870412 3.89063760523879 0.000151066511354501 -3.65887490088304 23.3626738147555 -0.156611992698034 0.875765535488494 BACH2 other 0.110892217743424 1 1 3.89063760523879 -0.156611992698034 0.00544379060452088 55.4519578396169 19.3182433871991 2.87044513976676 0.00467594665194809 -10.5496779245248 54.7048138425176 -0.19284734164154 0.847332617885391 RBM24 other 1 1 1 2.87044513976676 -0.19284734164154 2.07205601142724e-10 131.599723727421 19.5698660156903 6.72461035869688 3.29475394315253e-10 32.9675485214576 55.253638398885 0.596658418825915 0.551617289614484 CAP2 other 2.41995421574587e-06 1 4.21959137499544e-06 6.72461035869688 0.596658418825915 0.269204754081008 1.06980133299787 0.93397079086639 1.14543339412732 0.253818170325371 -5.21668245346595 6.08648764634969 -0.857092424494544 0.392734305979238 TREML2 other 1 1 1 1.14543339412732 -0.857092424494544 4.55965075254004e-18 184.232738863103 23.2098286656485 7.93770352711717 7.07355901032526e-13 -189.371940650504 69.6042417948441 -2.72069540256857 0.00737267555572345 ZNF451 other 6.36116876486862e-14 1 9.62782116895371e-09 7.93770352711717 -2.72069540256857 0.00815225286933486 106.365628006153 41.9520019071035 2.53541245163184 0.0123715180637215 -77.2430700552796 125.810376568681 -0.61396422268168 0.540272193207722 BAG2 other 1 1 1 2.53541245163184 -0.61396422268168 0.000141684016647603 113.280757517322 30.5298833626523 3.71048772678576 0.000301353330133983 -42.5684771188805 91.5564442182868 -0.464942445966881 0.642721727372267 RAB23 other 1 1 1 3.71048772678576 -0.464942445966881 0.000182696570216068 50.0519655812383 14.7912419358325 3.38389202193935 0.000910595898557397 -0.243941285641939 30.0536737251096 -0.00811685412815697 0.993534472296521 GPR63 other 1 1 1 3.38389202193935 -0.00811685412815697 3.24551210870006e-12 180.674268472388 31.7794110584743 5.68526169789447 6.42917206418307e-08 -55.1854287737384 65.8375616907899 -0.83820584111119 0.403222667957352 FBXL4 other 4.0555919310316e-08 1 0.00075504196721766 5.68526169789447 -0.83820584111119 1.97674133508803e-10 284.013045724619 71.2587131862361 3.98566060240725 0.000103877332883038 -318.098659327411 145.840173048485 -2.18114565197107 0.0306995550154258 CCNC other 2.31100829485142e-06 1 0.949023313219439 3.98566060240725 -2.18114565197107 1.2405910446273e-13 200.647265296769 26.8868364104998 7.46265801723003 5.95900516630764e-12 -76.0915463550024 79.316787707325 -0.95933721667822 0.338902446298162 E2F3 other 1.61475330368689e-09 1 7.98208742026908e-08 7.46265801723003 -0.95933721667822 0.00994543559483279 238.770559282847 144.342900612561 1.65418983732178 0.100395174023778 -357.849607806982 283.115448135516 -1.26397061751181 0.208402703553979 PTP4A1 other 1 1 1 1.65418983732178 -1.26397061751181 1.39800790745257e-06 126.07646602945 37.5306594173851 3.35929258868945 0.00098648644834207 -93.7737615007055 76.8113486662347 -1.22083211828732 0.224027660365561 ASCC3 other 0.012587663198703 1 1 3.35929258868945 -1.22083211828732 0.647391742523202 15.279496271312 22.8573008677223 0.668473340738529 0.504832222038702 -5.56860617617041 47.1508198230285 -0.118102001133195 0.906140740017185 BVES other 1 1 1 0.668473340738529 -0.118102001133195 0.00110667435068774 232.765556663853 76.7811411762522 3.03154593820814 0.00286706228940115 -15.8657638302768 148.465230128856 -0.106865181945339 0.915038729404584 COL9A1 other 1 1 1 3.03154593820814 -0.106865181945339 7.03929226645718e-22 282.448812111701 32.5959084836174 8.6651615264431 5.21954350237213e-15 -60.5134031359736 67.3034958754708 -0.899112332113318 0.36996974210885 MED23 other 1.00401425596479e-17 1 7.2781314597077e-11 8.6651615264431 -0.899112332113318 7.24191331843245e-08 193.844929035434 49.7066563601976 3.89977808265241 0.000144487729058301 -126.18607783983 104.085610643602 -1.2123297068593 0.227279630249978 WASF1 other 0.000729188252032964 1 1 3.89977808265241 -1.2123297068593 1.05696996850413e-13 29.5004643730046 4.09917887173696 7.19667652865909 2.53637392325716e-11 -17.6456001662329 11.9242370065941 -1.47980958081216 0.140966860065033 GPLD1 other 1.37776035394514e-09 1 3.35612997525387e-07 7.19667652865909 -1.47980958081216 1.03367403665925e-07 214.675390067584 50.7337898705968 4.23140850733095 3.97392341076486e-05 -335.348662043218 147.581199452123 -2.27229933953755 0.0244523902693651 ALDH5A1 other 0.00102757535984296 1 0.379350728791613 4.23140850733095 -2.27229933953755 0.0414842916597795 -65.8783577775151 68.5276581688709 -0.961339691707731 0.337928511570505 -348.936039159562 141.759287002514 -2.46146863840655 0.0149702888739665 CRYBG1 other 1 1 1 -0.961339691707731 -2.46146863840655 0.0561096686536927 -117.503888376297 61.5368339630197 -1.90948868846438 0.0580346405783791 -293.501032506701 126.889068794181 -2.31305214307128 0.0220260853704424 VNN1 other 1 1 1 -1.90948868846438 -2.31305214307128 0.0111526540320832 -17.4405257310712 7.70238930674229 -2.26430073013898 0.0249333672236048 -47.0124559850867 15.8823414153891 -2.96004567308535 0.00355634946554382 VNN2 other 1 1 1 -2.26430073013898 -2.96004567308535 2.41443561717304e-07 158.639950358082 36.4859066635473 4.3479788462151 2.47838072745825e-05 -198.316977308178 106.059886211531 -1.86985847705555 0.0633894990067995 ACOT13 other 0.00232486005577592 1 0.241964310421749 4.3479788462151 -1.86985847705555 4.48994435789896e-09 194.930498561388 44.441526151313 4.38622422411183 2.1694710971422e-05 -130.576870302001 85.8900218066769 -1.52027985970136 0.130559875956005 SMAP1 other 4.88685543913722e-05 1 0.213063756450336 4.38622422411183 -1.52027985970136 2.26524346146113e-08 4180.68613583943 985.668260185664 4.24147383527592 3.80528235207611e-05 -2826.56921119351 2036.35276305725 -1.38805479211268 0.167112269039903 RPS12 essential 0.000236174283291938 1 0.364089415446642 4.24147383527592 -1.38805479211268 2.84008757853907e-12 779.501950806713 127.330723265249 6.12186855471554 7.27611354456817e-09 -836.023235978576 368.672303616385 -2.26765945740389 0.0247317414298386 C6orf62 other 3.55635766584662e-08 1 8.91032864667818e-05 6.12186855471554 -2.26765945740389 9.53433000765266e-09 143.792607975517 33.2471623216172 4.32495882158412 2.76980488688473e-05 -89.9732467903712 64.1865923001978 -1.40174518643349 0.163057199607077 B3GAT2 other 0.000101798041491707 1 0.269280431102934 4.32495882158412 -1.40174518643349 0.000160366383388138 107.673728690888 33.6747559980097 3.19746128813086 0.00168087354485109 -134.809001325034 97.5016048691073 -1.38263366542541 0.168766027401156 GMNN other 1 1 1 3.19746128813086 -1.38263366542541 0.000309015008601723 200.247812577442 53.1616965504459 3.76676866185834 0.00023442573068284 84.027011570941 109.830022972354 0.765064135442201 0.445396655617421 EYA4 other 1 1 1 3.76676866185834 0.765064135442201 0.203644635138245 56.6166299644782 32.7611922395496 1.72816146465299 0.0859901068354105 44.6470724932775 67.8745872741941 0.657787756600507 0.511669462013316 SOBP other 1 1 1 1.72816146465299 0.657787756600507 1.21373415376694e-07 369.663773953737 164.443529781366 2.24796788566397 0.0260265264568656 -1012.03250106132 342.075578175942 -2.95850556317936 0.0035897771003081 SNX3 other 0.00119904797050636 1 1 2.24796788566397 -2.95850556317936 8.75280037570338e-18 320.823785245004 40.2023635138559 7.98022198705881 3.12135734511587e-13 -55.2381193539558 81.0046144566724 -0.681913243146184 0.496318109590402 HBS1L other 1.21725194824907e-13 1 4.26783189797693e-09 7.98022198705881 -0.681913243146184 2.52684769433412e-05 147.515590116223 50.1959229179371 2.93879625158778 0.003802239350906 -359.741594278815 156.424459667768 -2.29977840449553 0.0228039629517157 TRIM38 other 0.200151605868206 1 1 2.93879625158778 -2.29977840449553 3.82319628487275e-14 45.7279597998095 8.41390261760426 5.43480972838141 2.10388628375937e-07 -42.6310761250583 17.242511145962 -2.47244010829838 0.0145069235740239 PEX7 other 5.04241358011867e-10 1 0.00239864075211406 5.43480972838141 -2.47244010829838 1.79146776287231e-19 135.117161703351 17.1185792415502 7.89301260325361 7.24050470569768e-13 -48.3626613109989 35.5905646437361 -1.35886187238422 0.176344844362219 ZBTB24 other 2.52346149078193e-15 1 9.8528788035134e-09 7.89301260325361 -1.35886187238422 1.01041061209648e-20 184.007972911393 21.835000497461 8.42720259762713 2.59352716649432e-14 -28.2852785529681 45.722434913193 -0.618630189023605 0.537092099083606 FIG4 other 1.43346953538127e-16 1 3.59021965657809e-10 8.42720259762713 -0.618630189023605 2.7008950399023e-06 585.150531762299 309.032565773466 1.89349148461991 0.0601559766870745 -1831.29122669976 623.370508954918 -2.93772515765932 0.00381129052166201 PERP other 0.0236220280189855 1 1 1.89349148461991 -2.93772515765932 0.962216298388923 -1.99989976531251 38.2390880540897 -0.052299881275506 0.958357090159922 -19.5098834858168 77.1346531799612 -0.252932795851155 0.800655283150499 ARFGEF3 other 1 1 1 -0.052299881275506 -0.252932795851155 0.000241831828932854 42.2091983236973 12.400736728885 3.40376537672794 0.000848641774315651 5.10290636762256 25.9107662112851 0.19694154646033 0.844134654708419 SLC16A10 other 1 1 1 3.40376537672794 0.19694154646033 1.88858707777204e-16 240.339859437751 30.778191226292 7.80877140149946 8.30315328668168e-13 -8.40478580990623 61.3604237354561 -0.136974050996484 0.891230216703837 HECA other 2.58887516620992e-12 1 1.12906278392297e-08 7.80877140149946 -0.136974050996484 0.00169627837044672 261.150571273123 80.5268563955468 3.24302453817835 0.00145020040429235 79.3419477693145 163.842975418593 0.484256023589709 0.628892156035669 ADGRG6 other 1 1 1 3.24302453817835 0.484256023589709 1.30310315235992e-05 82.5647955334511 40.4548810845153 2.04091059768444 0.0429672988630114 -206.794069809727 82.665433600273 -2.50157848091229 0.0134094522095458 PHACTR2 other 0.106424434453234 1 1 2.04091059768444 -2.50157848091229 3.47492591222504e-09 35.5161752714921 8.31564402192248 4.27100717369106 3.37009943736328e-05 -30.0950815471893 17.0984402363714 -1.76010683612952 0.080349595582768 EPM2A other 3.81060375534598e-05 1 0.32450687482371 4.27100717369106 -1.76010683612952 8.54177894718569e-12 337.355798160891 70.1681202107349 4.80782151706095 3.59873709784106e-06 -687.336562593494 208.636513196515 -3.2944212499664 0.00122381778558105 SLC39A7 essential 1.05285967303011e-07 1 0.0379198927999513 4.80782151706095 -3.2944212499664 0.078949251631251 4.08321159397826 1.87277147610671 2.18030424217418 0.0307431993145095 2.58291515703406 3.80649674690067 0.678554410728741 0.498432077525275 CCR6 other 1 1 1 2.18030424217418 0.678554410728741 0.115599420492461 20.024259666672 13.5738143361696 1.47521243261109 0.142183848332563 -10.9113736724648 27.4609586629743 -0.397341323963926 0.691662405405995 UNC93A other 1 1 1 1.47521243261109 -0.397341323963926 1.34715322049864e-09 204.644480531761 39.5896652062399 5.16913895244325 7.2483834579205e-07 -209.893845711591 117.988572909153 -1.77893367583318 0.0772362628713005 PHF1 other 1.51123648275537e-05 1 0.00798481921724522 5.16913895244325 -1.77893367583318 6.49656967311856e-07 690.49995334986 191.055137458136 3.61413967997151 0.000408336763270702 -1291.24475690233 569.399182797196 -2.26773201633174 0.0247454192555614 CUTA other 0.00602296974394822 1 1 3.61413967997151 -2.26773201633174 0.000713407050681943 26.0727760631139 9.2775871002115 2.81029709357506 0.00560142894040256 -10.9581604119492 19.4847564125452 -0.562396582227419 0.574674318772924 PACRG other 1 1 1 2.81029709357506 -0.562396582227419 0.000142552839355454 318.062070858137 105.986730766667 3.00096123880225 0.00313739197119251 -195.85203630577 222.865773651083 -0.878789206154166 0.38087586224724 QKI other 1 1 1 3.00096123880225 -0.878789206154166 0.771558731987922 5.29824145340608 8.45784075170287 0.626429559144792 0.531948801948801 11.4331256422971 17.6627195016958 0.647302678457833 0.518387460473656 C6orf118 other 1 1 1 0.626429559144792 0.647302678457833 0.678818491693652 32.4606357214209 39.9500279193149 0.812530989639857 0.417725239937488 61.6940976938389 83.428638341495 0.739483454605947 0.460724784919722 PDE10A other 1 1 1 0.812530989639857 0.739483454605947 0.000431319076516684 154.240849907264 38.7576588126337 3.97962247030738 0.00010657927618504 61.8310930137253 252.416650418583 0.244956475379856 0.806820522313292 MDFI other 1 1 0.971683260979011 3.97962247030738 0.244956475379856 1.66354964996937e-05 33.3714190862009 8.64816729225629 3.85878509959933 0.000168399827143017 -111.404952989348 56.9956649908773 -1.95462151388494 0.052474821844272 TFEB other 0.134198550263029 1 1 3.85878509959933 -1.95462151388494 0.541794932474524 -60.2041883631422 65.355513072899 -0.921179951505989 0.358587667021139 -3.17137197192618 135.606509186843 -0.0233865762856307 0.98137619127266 SMOC2 other 1 1 1 -0.921179951505989 -0.0233865762856307 2.77263670155813e-10 251.929238797025 45.2402863289874 5.56869240316022 1.18642687627404e-07 -972.549535500822 309.619113209551 -3.1411159518521 0.00203538807584503 CCND3 other 3.21875394683884e-06 1 0.00137388232272534 5.56869240316022 -3.1411159518521 1.2189236085677e-43 139.648309417199 7.35009555113436 18.9995229920034 2.03481714949394e-41 -152.019604448881 50.3031755811308 -3.02206774607496 0.00296240236530198 BYSL essential 1.77682494420914e-39 1 2.96472858681267e-37 18.9995229920034 -3.02206774607496 4.75351951260872e-19 296.241530130518 36.1529383193469 8.19412042013713 1.71639128299659e-13 -94.417569193743 74.8090349273312 -1.26211451979643 0.209083664539311 FAM120B other 6.67917026716652e-15 1 2.35385900550153e-09 8.19412042013713 -1.26211451979643 1.3460843811094e-14 113.507092739475 18.5834744871193 6.10795859612529 1.02524017752974e-08 -80.0157870652837 38.509674624836 -2.07781000085831 0.0396354807201835 TBP essential 1.79109987750416e-10 1 0.000124699962792943 6.10795859612529 -2.07781000085831 0.133135821076208 7.34338977784683 4.2617788404394 1.72308091357686 0.0869346266377178 -2.49515302159391 12.4253069556711 -0.20081218359399 0.841117465298962 PRPH2 other 1 1 1 1.72308091357686 -0.20081218359399 8.62596182987635e-18 344.621660409994 38.1278288061403 9.03858601973407 7.7772630845809e-16 -30.0165013192282 111.19649835515 -0.269941066159823 0.787579099649815 BICRAL other 1.1996987712992e-13 1 1.09169441918262e-11 9.03858601973407 -0.269941066159823 2.52204388590369e-17 348.5073395778 46.4478618234027 7.50319446141232 5.48413464824415e-12 -378.819441726083 140.934375784403 -2.68791371599494 0.00801960373748923 PPP2R5D other 3.49227416881084e-13 1 7.35257932290093e-08 7.50319446141232 -2.68791371599494 1.80499692245137e-07 179.484272333287 48.7638750864257 3.68068107826094 0.000325896945417077 -372.625005825062 147.961736586792 -2.51838762115694 0.0128600503712169 MRPL2 essential 0.00175896950092886 1 1 3.68068107826094 -2.51838762115694 1.08731463611107e-13 1852.28689585334 238.042870210126 7.78131642513925 1.10665467277814e-12 126.296955655047 722.289624269448 0.174856389198154 0.86142985644828 PTK7 other 1.41687970231634e-09 1 1.50161972549266e-08 7.78131642513925 0.174856389198154 3.42139563094078e-08 269.212066729545 59.9406881040195 4.49130757829075 1.41599339020806e-05 -347.511256189577 181.207821418503 -1.91774976085052 0.0570688216221171 SRF essential 0.000352164252292735 1 0.141514379417394 4.49130757829075 -1.91774976085052 6.29423271903677e-13 313.500631871604 42.2735402710357 7.41600135360329 9.07569529051952e-12 -21.4290534563374 130.43760754048 -0.1642858517601 0.869733341105024 CUL9 other 8.03962345202567e-09 1 1.2106069948024e-07 7.41600135360329 -0.1642858517601 0.00273833671298214 101.990648300265 79.2436530622766 1.28705132031346 0.200113164350438 -586.960008846204 244.511163530187 -2.40054482736833 0.0176300960713589 DNPH1 other 1 1 1 1.28705132031346 -2.40054482736833 0.236061633850382 -3.05083361465321 32.3717008517008 -0.0942438467669492 0.92505728844306 -124.765571515171 81.0406888648658 -1.53954233685274 0.126047771628437 DUSP22 other 1 1 1 -0.0942438467669492 -1.53954233685274 2.14525639813853e-09 142.583496368557 26.2163609482454 5.43872189775066 2.46410851304387e-07 -65.6997418236717 65.5652087746498 -1.00205189690594 0.318124597139346 EXOC2 other 2.37951839681525e-05 1 0.0027972559840074 5.43872189775066 -1.00205189690594 0.0297377252317229 66.6427694226114 286.877045922689 0.232304293319345 0.816616229146824 -1166.02568016929 549.225249580254 -2.12303728035159 0.0353812570002496 COX7A2 other 1 1 1 0.232304293319345 -2.12303728035159 1.66647766346359e-05 517.384728057665 142.554582845057 3.62937983284629 0.000389046463360934 -208.027733878117 274.35040582159 -0.758255608389357 0.449487675206335 TMEM30A other 0.134384758781704 1 1 3.62937983284629 -0.758255608389357 0.106283524432632 -28.3949450865668 47.3127095189411 -0.600154702093297 0.549387397950907 -245.092657426503 117.127568527425 -2.09252749380787 0.0382225529673766 GMDS other 1 1 1 -0.600154702093297 -2.09252749380787 2.74434145830535e-13 341.593376196173 51.8003949165728 6.59441644694651 6.96419203297051e-10 -81.3304347141779 100.018534830775 -0.813153630492424 0.417427423548336 SENP6 essential 3.54102378365139e-09 1 8.83129191700991e-06 6.59441644694651 -0.813153630492424 0.247332084220178 274.353070435922 387.541428630714 0.707932236832806 0.480155932951579 -1226.73250979926 1176.54085011013 -1.04266036294824 0.29889002927157 VEGFA other 1 1 1 0.707932236832806 -1.04266036294824 6.64021731603792e-16 467.62130479103 57.8426165535621 8.08437329867354 1.93054577219533e-13 -99.6679044706573 148.278377832793 -0.672167486098671 0.502511103965379 PRPF4B other 9.04198391924884e-12 1 2.64600603537092e-09 8.08437329867354 -0.672167486098671 4.25648575737625e-06 173.337646911728 37.3006188900954 4.64704479629304 7.35050111038945e-06 42.7889472368091 71.9260834989131 0.59490167064992 0.552811562773452 TTK essential 0.0364993653695014 1 0.0754308423948166 4.64704479629304 0.59490167064992 1.85434900112142e-14 509.572970858029 67.2065940967439 7.58218710093385 4.03811375156368e-12 -172.425648847219 204.976782511467 -0.841195996612802 0.401652470013914 SLC29A1 other 2.46146286408858e-10 1 5.42682107072642e-08 7.58218710093385 -0.841195996612802 5.26650686974449e-05 42.0350054324629 15.1852869534247 2.76814034277982 0.00633448535774847 -36.2223817469249 31.7289551986838 -1.14161911478344 0.255395957708702 WISP3 other 0.400096526894489 1 1 2.76814034277982 -1.14161911478344 2.66137472596677e-08 68.3810581863629 14.4505603198337 4.73206966878016 5.22696149985556e-06 -110.791209554229 46.479288962254 -2.38366833976747 0.0184358365118178 BTN2A1 other 0.000276224082808091 1 0.0543813074444972 4.73206966878016 -2.38366833976747 0.74886111587218 -25.3105186061858 94.5283434641156 -0.267755867485333 0.789247865716967 77.3366574832164 197.51260440306 0.391553023752332 0.695933294779465 LAMA4 other 1 1 1 -0.267755867485333 0.391553023752332 0.0527799011258018 52.114223418461 30.0509206682434 1.73419723121938 0.0848841701093921 -28.3562774717631 57.7204122221585 -0.491269489944449 0.623935261321133 FAM46A other 1 1 1 1.73419723121938 -0.491269489944449 0.0569490949741811 -405.526368066679 205.534808828832 -1.97303011775684 0.0504476852872648 -1283.97289226647 610.534001169728 -2.10303257444547 0.0372395249284995 CLIC5 other 1 1 1 -1.97303011775684 -2.10303257444547 8.115320457155e-10 814.324716600097 175.98032652415 4.62736223238196 8.02587983355604e-06 -617.488275491388 341.261251809779 -1.80942979086175 0.0724135502354565 FBRSL1 other 9.20358493045949e-06 1 0.0821609318561132 4.62736223238196 -1.80942979086175 0.000220763959189778 91.7174382345882 46.8306632616576 1.9584911219842 0.0521745282079293 -366.54569441113 140.534677921409 -2.60822239629789 0.0100962085493673 ENPP5 other 1 1 1 1.9584911219842 -2.60822239629789 0.0842439949380001 -22.6551795401705 10.1736765310892 -2.2268429186774 0.0274376361173127 -19.0358822009816 26.925449349742 -0.706984754598497 0.480665551562138 LY86 other 1 1 1 -2.2268429186774 -0.706984754598497 0.116469580645605 11.5942839896816 35.5655340191142 0.325997747804108 0.744886545717483 -175.037063881816 101.793565106548 -1.71952975316861 0.0876084887523557 PRSS16 other 1 1 1 0.325997747804108 -1.71952975316861 0.638622399606228 0.847126195099639 28.727488556514 0.0294883485353456 0.976513793979069 -42.4979035509764 55.5199416285405 -0.765452958061648 0.445188792650565 TBX18 other 1 1 1 0.0294883485353456 -0.765452958061648 8.9361048399302e-14 325.489626721318 102.036996709354 3.18991774766222 0.00172879756872894 -481.554752409069 142.04932746407 -3.39005302598757 0.000890436563633994 ERBIN other 1.16759145838528e-09 1 1 3.18991774766222 -3.39005302598757 0.00709652134509008 104.079762130673 43.1494259933353 2.41207755919509 0.0170863239854065 -106.382407730753 100.54845121503 -1.05802134637804 0.291769524767777 PCDHB2 other 1 1 1 2.41207755919509 -1.05802134637804 4.05143218236847e-10 159.652215189874 27.2019226680652 5.8691518661401 2.92374593528161e-08 -28.8655249441548 40.0067573623447 -0.721516234937945 0.471770011731304 HARS2 essential 4.666439587652e-06 1 0.000348627465322979 5.8691518661401 -0.721516234937945 3.50384731171557e-09 36.8562875235369 24.3408121816442 1.51417657095809 0.132004510809492 -140.205823685793 35.2814810221466 -3.97392115137639 0.000107788915924294 NUDT12 other 3.84126780783378e-05 1 1 1.51417657095809 -3.97392115137639 5.47917973221501e-09 71.6732528226383 10.732269545057 6.6782941410234 7.96218279748276e-10 67.8122052308136 37.043325824512 1.83061870718804 0.0696387867400886 CEP72 other 5.93121206012275e-05 1 1.00801234216132e-05 6.6782941410234 1.83061870718804 0.0129570305016903 52.2149999413868 54.0094138732258 0.966775904362692 0.335142949787962 -127.334814259089 81.661388583351 -1.5593025843434 0.120938285374813 MAN2A1 other 1 1 1 0.966775904362692 -1.5593025843434 0.0146578309396727 99.7571557119084 34.3857610951903 2.90111815282349 0.00427455617784931 170.111448234699 140.359081922949 1.21197321829222 0.227415664833776 SEMA5A other 1 1 1 2.90111815282349 1.21197321829222 0.907241350887884 -26.0237892646955 122.778263443281 -0.21195762616986 0.83242404370741 182.079185279728 525.588131599926 0.3464294079957 0.729499118606061 C7 other 1 1 1 -0.21195762616986 0.3464294079957 1.19110294616468e-06 166.293593741741 31.1100653169164 5.3453309097142 3.22171838714147e-07 27.6916679880891 127.742792719397 0.216776754277772 0.82867111083962 PAPD7 other 0.010798539309929 1 0.00362991010679229 5.3453309097142 0.216776754277772 0.0373322167010269 21.866986821109 9.23113473675366 2.3688297749621 0.019153549179507 -30.7329957434872 42.011532324954 -0.731537129038078 0.465623660696547 GHR other 1 1 1 2.3688297749621 -0.731537129038078 0.00412856861943082 199.408432630614 61.6148325373736 3.23637060134278 0.00150662403900556 -146.737256339749 274.701541141874 -0.534169760132377 0.594059377462301 HMGCS1 essential 1 1 1 3.23637060134278 -0.534169760132377 9.76770691116282e-07 594.357680992054 121.391005627983 4.89622503675051 2.49978933792254e-06 -627.02037907742 493.994078550024 -1.26928723704109 0.206304506815788 DAP other 0.00891986995127389 1 0.0266277560275508 4.89622503675051 -1.26928723704109 0.0185419076394938 2.7169841560582 26.2274099684689 0.103593307891424 0.917626013803169 -95.5002289586957 39.3717139422813 -2.42560507014499 0.016431482901768 NME5 other 1 1 1 0.103593307891424 -2.42560507014499 2.66042577097067e-07 389.943584577341 92.3767333774073 4.22123158419358 4.1248867272059e-05 -182.728546570199 138.672874135501 -1.31769495446997 0.18955008196315 BRD8 essential 0.00255055018662958 1 0.393142953969994 4.22123158419358 -1.31769495446997 0.0632861434909947 264.809529260921 119.573858002013 2.21461056526639 0.0282459172652423 329.957070244527 179.500291408494 1.83819796422299 0.0679474305777234 KIF20A essential 1 1 1 2.21461056526639 1.83819796422299 8.32231173865742e-07 1042.17736349254 296.140578625152 3.51919810628756 0.000570328193407806 -862.999352509637 426.454329388817 -2.02366183911526 0.0447455684130694 HSPA9 essential 0.00764321110078297 1 1 3.51919810628756 -2.02366183911526 9.36852734503667e-15 354.278738185637 94.0683794431031 3.76618307111288 0.000239733936538007 -436.437757492528 134.105740975449 -3.25443008120308 0.00141202586592326 MRPS27 essential 1.25032365946859e-10 1 1 3.76618307111288 -3.25443008120308 3.98617293744111e-05 275.805485299966 76.039548971913 3.62713205205677 0.000390639217675002 -97.4447355876524 110.000921180426 -0.885853814149622 0.377095620054615 PFDN1 essential 0.306734917276332 1 1 3.62713205205677 -0.885853814149622 0.714471731404617 28.9501902214341 36.6046774204985 0.790887729698231 0.430241806153612 9.26297316253387 52.9533419149353 0.174927074053494 0.861369729747282 HBEGF other 1 1 1 0.790887729698231 0.174927074053494 0.501595877524982 80.0776727863406 175.635558507736 0.455930868821268 0.64907782217666 293.198555037668 254.737581183841 1.15098272377043 0.251511802115346 LOX other 1 1 1 0.455930868821268 1.15098272377043 0.511416677763568 -3.59207343105173 8.16040227184226 -0.440183377165891 0.660425517961519 6.40024192400728 12.1366658519981 0.527347625950631 0.598716057213825 GZMK other 1 1 1 -0.440183377165891 0.527347625950631 2.16412484923526e-09 161.014533266776 35.6337399023142 4.51859764672971 1.28188364492209e-05 -117.605833273907 52.5289785215876 -2.2388753138532 0.0266869089052809 TMCO6 other 2.39936522034714e-05 1 0.128816487478221 4.51859764672971 -2.2388753138532 0.568117281101153 206.025126990042 3857.434561685 0.0534098825775145 0.957474553027304 5685.08497935153 5791.15107138042 0.981684799667365 0.32779488487705 SPARC other 1 1 1 0.0534098825775145 0.981684799667365 0.00247065234195892 168.419567113296 97.9146079849596 1.72006578568099 0.0874424266030581 -132.916012579614 139.233535291243 -0.954626428910145 0.341272478921833 HMGCR essential 1 1 1 1.72006578568099 -0.954626428910145 3.27329407763594e-06 147.524375904883 74.1065121786551 1.99070731529279 0.0482940180028846 -211.307769929365 104.951719621641 -2.01338073059827 0.0458279832521572 COL4A3BP other 0.0283729130649483 1 1 1.99070731529279 -2.01338073059827 0.0150482842360329 179.119728341049 81.4962268542711 2.19788983189793 0.0294596506749366 -117.392811721015 131.808440539756 -0.890631975010794 0.374525010042695 FAF2 essential 1 1 1 2.19788983189793 -0.890631975010794 0.700079184076237 14.9967864794097 17.7940329005558 0.842798625990022 0.400701046383522 9.70711905328663 42.4952780382805 0.228428180762632 0.819628697238027 PCDHB3 other 1 1 1 0.842798625990022 0.228428180762632 0.291864103632936 64.0489281460897 47.5475179126863 1.34705092837245 0.180008950036998 138.30966131088 112.651463491291 1.22776621824866 0.221470808362928 PCDHB5 other 1 1 1 1.34705092837245 1.22776621824866 0.533425402964633 15.2723302897975 16.8315610923342 0.907362674562208 0.365680168453402 -12.5135580117423 39.8780014842502 -0.313796016500089 0.754114854590826 PCDHB6 other 1 1 1 0.907362674562208 -0.313796016500089 0.896665493271978 5.40680825724494 11.5725976735436 0.467207830926809 0.641033705878803 4.48268736549594 27.4182569679995 0.163492791344387 0.870351997515647 PCDHB7 other 1 1 1 0.467207830926809 0.163492791344387 0.000601241242741388 2.71367553962325 17.9499713114705 0.151179937423584 0.880036901001755 -68.834225414672 25.5536210116604 -2.69371708155421 0.00787104617716523 PDE8B other 1 1 1 0.151179937423584 -2.69371708155421 2.25979949811197e-05 46.9861415752743 18.5980165103746 2.52640605782148 0.0125334581933683 -74.2823166863047 30.3962075695207 -2.44380212618334 0.0156627586655659 CLK4 other 0.179970432029637 1 1 2.52640605782148 -2.44380212618334 0.65148812117654 3.05297537382121 12.4735560032221 0.244755815665764 0.806984526111063 -21.8954689915076 29.527263678912 -0.74153396771219 0.45954480047899 PCDHB15 other 1 1 1 0.244755815665764 -0.74153396771219 0.138994639489956 4.41510468594218 2.34042689580319 1.8864527210225 0.0611164362506919 1.08465059367353 3.82514456240204 0.283558065840108 0.777129924193895 GRM6 other 1 1 1 1.8864527210225 0.283558065840108 0.819223653709597 4.66219946354543 7.37852262608934 0.631860834452225 0.528420806154554 3.32631065593752 11.703355504254 0.284218543538941 0.776627193693545 ITK other 1 1 1 0.631860834452225 0.284218543538941 0.011149523163707 214.438426287052 111.542124707199 1.92248826934181 0.0564523391821951 -210.268151120781 180.041411006368 -1.16788770953003 0.244717458916387 RNF130 other 1 1 1 1.92248826934181 -1.16788770953003 4.13419499563901e-06 59.1252273531966 23.1185738919781 2.55747727474281 0.0115158698348757 -102.951932077778 36.933699493865 -2.78747955088764 0.00598586553949869 THG1L essential 0.0355003324275521 1 1 2.55747727474281 -2.78747955088764 0.499834973638528 -10.3021931674402 26.3940337915526 -0.390322799796422 0.696830323631277 -39.9845119265199 37.2014523447035 -1.07481050890242 0.284119156918271 ARSB other 1 1 1 -0.390322799796422 -1.07481050890242 0.000416836724148883 351.028502313842 166.453395428754 2.10886958124018 0.0365738478980338 -546.586463074157 266.42035392275 -2.05159423830149 0.0419030366007015 CLINT1 other 1 1 1 2.10886958124018 -2.05159423830149 0.901252599759833 38.7886336850649 93.6241899847361 0.414301407482284 0.679222488055302 19.9005624820155 131.812749411942 0.15097600627252 0.880189692902977 THBS4 other 1 1 1 0.414301407482284 0.15097600627252 0.000156707061640156 159.638856461273 54.2428506400092 2.94303958176424 0.0037781685972065 -130.588886915034 89.8020043415916 -1.45418677314034 0.148026326438416 CNOT6 other 1 1 1 2.94303958176424 -1.45418677314034 0.000284049560370761 205.181429931308 69.7159518943237 2.94310590841999 0.00375252146490607 -139.852254308762 111.979039401729 -1.24891457415559 0.213591438701865 TTC1 essential 1 1 1 2.94310590841999 -1.24891457415559 1.98324292327043e-14 104.625197765652 27.427878822182 3.81455665762374 0.000196596094046384 -117.036405024055 38.5573007554054 -3.03538895957719 0.00281840498769966 MSH3 other 2.63156503488754e-10 1 1 3.81455665762374 -3.03538895957719 0.684468621968722 -15.2043524587517 18.0217766362818 -0.843665570027209 0.400156446330135 -10.9334861644765 25.3344805267948 -0.431565437187978 0.666656958167112 RASGRF2 other 1 1 1 -0.843665570027209 -0.431565437187978 0.00371034287255151 569.261104622461 236.233742745384 2.40973663629425 0.0171754818184816 -437.368397731513 387.677885357393 -1.12817474055378 0.261047363444152 CCNG1 other 1 1 1 2.40973663629425 -1.12817474055378 6.79827952274779e-13 36.337734502447 7.89269458994535 4.60397068305903 8.65640081072552e-06 -21.7669540899558 11.5630248892245 -1.88246192484115 0.061671998461724 POLR3G other 8.67256518716936e-09 1 0.0884164778807505 4.60397068305903 -1.88246192484115 3.75762672342804e-12 471.195131430187 60.3136268649382 7.81241579925787 8.80147710197395e-13 21.818604057051 252.040461188558 0.0865678627715569 0.931129697798481 DROSHA other 4.68613628678711e-08 1 1.19656081201336e-08 7.81241579925787 0.0865678627715569 0.000384709243630603 1617.53896103896 397.468852523088 4.06959929255086 7.52412409713556e-05 1296.47752247752 1662.30979367346 0.779925334863423 0.436639667254828 CDH6 other 1 1 0.697561545045437 4.06959929255086 0.779925334863423 0.00657397246948762 446.420304481941 154.85539989337 2.88282039108313 0.00449780904590735 90.1055338384344 227.507238073551 0.396055679816675 0.692605121559975 LMNB1 other 1 1 1 2.88282039108313 0.396055679816675 2.89970423719831e-07 310.82150590638 193.181942774895 1.60895734581448 0.109673751695173 -853.505818354661 282.722091099375 -3.0188861968153 0.00297029270135725 ARRDC3 other 0.00276979748737183 1 1 1.60895734581448 -3.0188861968153 2.00688215460054e-08 547.43087801558 87.4581907027867 6.25934373460732 3.70851807227359e-09 118.965761871797 350.696164410295 0.339227439432766 0.734903561707833 GOLPH3 other 0.000210060355122038 1 4.59077452166748e-05 6.25934373460732 0.339227439432766 4.35967216081972e-06 957.418898973674 202.559316253926 4.72661004529391 5.11182433913491e-06 -1115.74935291321 838.048416527113 -1.33136622050656 0.185035991703403 SUB1 other 0.037314434024456 1 0.0532294268434119 4.72661004529391 -1.33136622050656 0.15672837514684 78.4172926682694 40.9391969979318 1.91545751794377 0.0572995979847017 3.07101049178695 169.378855719853 0.0181310145161584 0.985557958416982 NPR3 other 1 1 1 1.91545751794377 0.0181310145161584 0.0387743627847358 95.7064153001902 43.7336708006456 2.18839199975817 0.0301476056819011 5.52449874445247 64.9875491612545 0.0850085718841998 0.932364989650692 SLC27A6 other 1 1 1 2.18839199975817 0.0850085718841998 1.79436301793166e-07 428.633864182693 76.7762152142309 5.5828991177367 1.05120938603792e-07 -288.016783102966 317.64832808383 -0.906715879288231 0.365982848875467 TARS essential 0.00174896563357799 1 0.001219928492497 5.5828991177367 -0.906715879288231 8.23849001223503e-06 225.592437922501 94.3097065845127 2.39203838175812 0.017937617844597 -236.855292923531 136.352614150547 -1.73707922212638 0.0843344080949357 LNPEP other 0.0686678142519789 1 1 2.39203838175812 -1.73707922212638 8.97576750628263e-07 107.661013828957 30.4166388816968 3.5395434139747 0.000530288513328156 -29.56996951444 44.4677576833274 -0.664975502588179 0.507060765844943 PDE4D other 0.00822000788225364 1 1 3.5395434139747 -0.664975502588179 8.69593429893867e-14 175.836129729043 20.8005734625581 8.45342701947883 2.22687145664626e-14 -18.2965026523934 86.0599884487101 -0.212601732607688 0.831924354218386 RAD1 other 1.13673253155726e-09 1 3.0853304031834e-10 8.45342701947883 -0.212601732607688 1.93559741984135e-10 189.645621513676 27.8275253094195 6.81503724837085 2.14461618432069e-10 -148.075085367922 115.134022065608 -1.28611059277981 0.200386154799094 BRIX1 essential 2.26329406302049e-06 1 2.76569703129996e-06 6.81503724837085 -1.28611059277981 0.602474482761503 15.7897589021949 15.8002178110672 0.999338052867539 0.319229698507818 1.55016041421808 65.3715901032819 0.0237130596298629 0.981112796472049 PRLR other 1 1 1 0.999338052867539 0.0237130596298629 0.000696839087678348 445.251429183936 118.781421217628 3.74849386898782 0.000275081406644107 51.7241675003583 409.984008470018 0.126161426864875 0.899815281549803 SLC12A7 other 1 1 1 3.74849386898782 0.126161426864875 3.01776313516983e-10 417.587612655161 72.576816796216 5.75373281839681 4.5697899674401e-08 -48.9009079089201 111.237814781538 -0.439606872941161 0.660838138129975 RAD50 other 3.49668214472128e-06 1 0.000540057778352071 5.75373281839681 -0.439606872941161 0.548921548614036 72.7622226063362 89.9328079138933 0.809073176898945 0.419697467887211 142.163181933012 130.289047079584 1.09113686161336 0.27688437041095 ST8SIA4 other 1 1 1 0.809073176898945 1.09113686161336 0.00969139104666867 218.910152657715 83.1666286310456 2.6321874081114 0.00935912754737502 -20.7017426889832 122.736760005642 -0.168667827699147 0.866282162506112 GNPDA1 other 1 1 1 2.6321874081114 -0.168667827699147 0.488030307289307 -22.2219308116475 20.0501400693856 -1.10831798355254 0.269498441448691 -28.4328569361132 30.0539759019529 -0.94605975025972 0.345639614161404 PCDH12 other 1 1 1 -1.10831798355254 -0.94605975025972 1.36094057587455e-05 658.086510408837 239.881746118927 2.74337885669122 0.00678878215796707 -839.503886394395 398.1430531326 -2.10854837172005 0.0365709580469954 SKP1 essential 0.110892217743424 1 1 2.74337885669122 -2.10854837172005 1.4810347433185e-12 326.609916562769 40.2864860482853 8.10718304324957 1.85882709127828e-13 129.654838400307 168.588606459404 0.769060502505115 0.443091295540754 NUP155 essential 1.87099119123426e-08 1 2.54808017672426e-09 8.10718304324957 0.769060502505115 3.84942499165052e-09 619.952121511592 134.250383672417 4.61787970024972 8.02142367660882e-06 -389.228031881753 222.82169654151 -1.7468138781954 0.0826251976257789 PPP2CA essential 4.20703657337485e-05 1 0.0821233356011211 4.61787970024972 -1.7468138781954 0.819160318634732 7.82962312461645 13.8035929774547 0.567216313709373 0.5713825361485 0.554965401951017 20.8068573145853 0.0266722356750144 0.978755247280647 FGF1 other 1 1 1 0.567216313709373 0.0266722356750144 0.504492736718641 17.8771610555052 77.0331339289887 0.2320710601231 0.816786979384133 -104.264786169245 116.115958270696 -0.897936749797787 0.370603030641306 NR3C1 other 1 1 1 0.2320710601231 -0.897936749797787 0.000314234370211401 159.105512707587 129.40316957819 1.22953335089254 0.220711320000936 -593.174713730207 214.776546587889 -2.76182256933474 0.00643389988216706 C5orf15 other 1 1 1 1.22953335089254 -2.76182256933474 2.23792026449197e-15 62.429901246918 22.8551214716413 2.73154974583623 0.00704999125465702 -136.877463847342 31.8174264125383 -4.30196528382329 3.01668511201022e-05 PPWD1 essential 3.02029718895836e-11 0.435518829620915 1 2.73154974583623 -4.30196528382329 4.2821329127922e-06 249.674207254702 49.2621077164914 5.06828105471254 1.1658042819714e-06 -45.0787368531487 201.759646367624 -0.223427913682061 0.823506474726024 LIFR other 0.0367038898771826 1 0.0126921112178227 5.06828105471254 -0.223427913682061 7.55770613371851e-15 24.9972556292798 11.4665591922222 2.18001365625318 0.0307951078565266 -74.2105596303066 15.9630043426474 -4.64890931790595 7.1902885181847e-06 TRIM23 other 1.01061646420084e-10 0.104510843611815 1 2.18001365625318 -4.64890931790595 6.1544316673049e-12 11.6097128591475 18.2868385621271 0.634867137898387 0.526469545460418 -129.440433876158 25.457757509204 -5.08451829778645 1.07008833868555e-06 TRAPPC13 other 7.62041729045693e-08 0.0156125888614222 1 0.634867137898387 -5.08451829778645 0.000265129248529709 -0.778155631126227 1.37660159366472 -0.565272940774867 0.572738297460657 22.3481562979262 5.61101365363266 3.98290891405293 0.00010612196863759 C9 other 1 1 1 -0.565272940774867 3.98290891405293 0.00189260606311107 99.206995189182 37.7526546990296 2.62781507631918 0.00944623810496173 -51.7215273263127 62.489862402436 -0.827678687996223 0.40910880640838 SEC24A other 1 1 1 2.62781507631918 -0.827678687996223 0.000155199873529199 98.0260163609867 41.4782747467542 2.36330987630235 0.0193369653953677 -129.514082230126 67.6495663350845 -1.91448503289159 0.0573770062140746 TXNDC15 other 1 1 1 2.36330987630235 -1.91448503289159 2.19818377462046e-06 41.4661642078254 7.99501950784437 5.18649944095078 6.88323408898286e-07 -11.8255826384434 32.5648403640776 -0.363139585707544 0.717015275537611 TTC33 other 0.0194275482000956 1 0.00759702546401039 5.18649944095078 -0.363139585707544 0.000181666554261454 268.621073558648 68.0152104101419 3.94942648767566 0.000119526478327962 -10.7727350184607 114.08448606581 -0.0944276946845027 0.924893780298948 RARS essential 1 1 1 3.94942648767566 -0.0944276946845027 0.0011502048639317 323.859004004286 158.466254032632 2.04370959597238 0.0427087703420673 -584.861356623185 267.63858957856 -2.18526542657448 0.0304004316225238 WWC1 other 1 1 1 2.04370959597238 -2.18526542657448 0.00250478832332537 595.682664072616 272.261296343891 2.18790798424839 0.0301641012014385 -571.305540249745 448.576927855546 -1.27359546328188 0.204701184463962 H2AFY other 1 1 1 2.18790798424839 -1.27359546328188 2.50799373669887e-05 288.621370695476 71.2706832126614 4.04965067942834 8.05989808059054e-05 -36.0129135719109 109.377739779948 -0.329252676498559 0.742406344055696 TCERG1 essential 0.198758503633385 1 0.744734582646566 4.04965067942834 -0.329252676498559 0.230562205695279 1227.53585025381 728.540721633857 1.68492414192152 0.0939899575045007 476.974777918785 1119.17943580033 0.426182578647632 0.670558542086781 DPYSL3 other 1 1 1 1.68492414192152 0.426182578647632 3.77191641353869e-05 214.061879556854 52.2779463750839 4.09468799751624 6.76773787989989e-05 6.23779231500318 85.6828126742008 0.0728009751351379 0.942057752803945 SMAD5 other 0.291531419602405 1 0.630482460891473 4.09468799751624 0.0728009751351379 0.00181129994294636 535.234513714295 191.051903265933 2.80151364401369 0.0057266875056527 -255.284389899765 305.532392847917 -0.835539523388069 0.40468374882792 CSNK1A1 essential 1 1 1 2.80151364401369 -0.835539523388069 1.02268140570993e-05 258.072226362585 59.6377530872745 4.32732980373891 2.70421696065808e-05 -27.0801222136114 96.1790901419788 -0.281559351140003 0.778659393678367 HMGXB3 other 0.0844695423616928 1 0.263336647628884 4.32732980373891 -0.281559351140003 0.000210855893150201 1014.12947495295 314.195197077052 3.22770521124246 0.00152678605725752 -692.679888350848 524.276695074609 -1.32121052653747 0.188403634902137 ERGIC1 other 1 1 1 3.22770521124246 -1.32121052653747 0.861745052333406 -111.098755662076 230.624470546898 -0.48173012776406 0.630681539494564 8.19872476089315 370.611269755254 0.02212216796944 0.982379140985916 PDGFRB other 1 1 1 -0.48173012776406 0.02212216796944 0.174722455633404 391.092364297648 259.055089720351 1.50968801547127 0.13318544544663 -202.482468122897 432.26805356778 -0.46841876574427 0.640151803526856 ATP6V0E1 other 1 1 1 1.50968801547127 -0.46841876574427 0.0491330877921627 21.5770019665476 10.3177266259096 2.09125544307057 0.0381577543335052 -7.70803747013173 17.2165063834143 -0.447712056004425 0.654994278836048 BNIP1 essential 1 1 1 2.09125544307057 -0.447712056004425 0.358177312547083 118.62586961578 82.5265604995496 1.43742655573811 0.152638832037421 78.655473557334 137.70660021887 0.571181580493016 0.568714615146314 STC2 other 1 1 1 1.43742655573811 0.571181580493016 0.186399892915811 41.0180478315114 38.8086253259914 1.05693122307118 0.292208943971249 -64.8696855638492 64.7573801750695 -1.00173424848992 0.318053614816252 CPEB4 other 1 1 1 1.05693122307118 -1.00173424848992 0.439228533926698 -10.3370203549073 14.0882474553342 -0.733733588061972 0.464241352437907 15.4066026628664 22.8472820310404 0.674329779880814 0.501125953278341 HRH2 other 1 1 1 -0.733733588061972 0.674329779880814 1.41220595105303e-05 1364.53642609496 294.473870971625 4.63381155547904 7.70073219926929e-06 330.810516728041 475.494893427994 0.69571833746336 0.487674609714481 DBN1 other 0.114798221761101 1 0.0789479065069088 4.63381155547904 0.69571833746336 0.00328329944021349 60.310652956248 20.4811779351829 2.94468673369833 0.00374477561356825 -12.69393837157 33.5092147122721 -0.378819333146625 0.705354143956747 ZNF346 other 1 1 1 2.94468673369833 -0.378819333146625 0.507028675890416 164.237714386404 149.130411459005 1.10130263022544 0.272517371925957 198.043836635602 243.267211463314 0.814099999109283 0.416869637643195 UNC5A other 1 1 1 1.10130263022544 0.814099999109283 1.41731097968162e-07 84.0071098848622 14.1970992632506 5.91720240361465 2.13694527458589e-08 54.1845887644953 59.8491401987729 0.905352835220952 0.366730390183235 EHHADH other 0.00139335842412501 1 0.000256454802403052 5.91720240361465 0.905352835220952 0.212274208998528 11.1410087128747 14.7050732084865 0.757630278674509 0.449830083285844 -33.1572356819584 34.3916083759089 -0.964108317341297 0.336503104935559 CNTN3 other 1 1 1 0.757630278674509 -0.964108317341297 1.35949640118312e-05 546.740859492749 121.876760590412 4.48601404274409 1.42323997794276e-05 944.854638133571 497.515044985442 1.89914787031459 0.059439603377677 SMC4 essential 0.110798956696424 1 0.14222437099582 4.48601404274409 1.89914787031459 0.000282995553345917 31.8657615641236 43.0344990152368 0.740470141242755 0.460180012883773 -301.453606579144 94.6841934875461 -3.18377963074475 0.00177009426078954 SELENOK other 1 1 1 0.740470141242755 -3.18377963074475 1.19362327312407e-16 124.091903733902 16.9227505157876 7.33284483619458 1.36607910800969e-11 -75.0428393938298 37.3907325621997 -2.00699034898542 0.0465716275340099 ACTR8 essential 1.6402771019271e-12 1 1.81702182156369e-07 7.33284483619458 -2.00699034898542 2.00052077924725e-06 79.4625696561875 14.8446102765146 5.35295761734506 3.15676388809072e-07 37.4012021168472 62.7942646081456 0.595614939521015 0.552324165417764 TBCCD1 other 0.0177486203534816 1 0.00355988263659991 5.35295761734506 0.595614939521015 1.08650917462957e-07 169.78922278329 37.8239739688903 4.48893135668239 1.42995791099926e-05 -100.449349376744 72.4987537227124 -1.38553208460568 0.16797429272049 CRBN other 0.00107803440306746 1 0.142867094887936 4.48893135668239 -1.38553208460568 0.430951446146843 124.62686763029 123.242221916245 1.0112351570145 0.313510919007908 -305.746042842757 487.803220402438 -0.626781517740937 0.531742719797799 BCL6 og 1 1 1 1.0112351570145 -0.626781517740937 0.249827841551957 580.537993686307 347.490044203998 1.67066079552339 0.0968601233622617 402.405878984662 1289.10468764623 0.312159192997282 0.755350179664918 CLDN16 other 1 1 1 1.67066079552339 0.312159192997282 0.000218394552302706 63.8173937320347 15.2065478769175 4.19670488322371 4.62029399355229e-05 62.7084293621785 61.7446015106019 1.0156099128992 0.3114505401882 NPHP3 other 1 1 0.43869691468779 4.19670488322371 1.0156099128992 4.46065845237909e-05 694.76803436528 163.886536936041 4.23932342066891 3.87613121023287e-05 -780.308324692638 624.409651632672 -1.2496737080414 0.213339544162171 AMOTL2 other 0.341686437452239 1 0.370519382386161 4.23932342066891 -1.2496737080414 5.83255035316208e-05 111.304877808565 37.0569929003009 3.00361332901518 0.00311772418961894 -437.965204002573 164.406912791061 -2.66390990845481 0.00855131530521373 NIT2 other 0.440649179181395 1 1 3.00361332901518 -2.66390990845481 1.23609601198473e-08 172.566616539453 30.7781309762369 5.60679323486823 9.29548571647446e-08 -32.0520712227672 63.711165491059 -0.503084050899449 0.615623941113791 OGG1 other 0.000131112703991221 1 0.0010818086276833 5.60679323486823 -0.503084050899449 7.25444033245693e-07 262.073423936352 48.4866962163358 5.40505838482053 2.47639739450623e-07 -96.5775769854533 186.053888555541 -0.519083894108575 0.604462198420257 PCCB other 0.00669149576265827 1 0.00281021576328567 5.40505838482053 -0.519083894108575 1.33231480400844e-16 607.344664405711 101.416354502524 5.98862646350193 1.65122166963202e-08 -473.643733732944 142.832592077087 -3.31607602190204 0.00115913800422981 UBE3A other 1.82926822590359e-12 1 0.000198972211190658 5.98862646350193 -3.31607602190204 4.5191414430702e-13 174.090840882259 21.4139516767265 8.12978582890272 1.28262436932417e-13 -5.63770306701529 84.2790104038832 -0.0668933230231133 0.946752835927117 ARMC8 other 5.79805847145907e-09 1 1.76155630882981e-09 8.12978582890272 -0.0668933230231133 0.00117707608488504 84.4042821992476 23.6264475809127 3.57244913397121 0.000471556513659006 -43.6247328912476 92.9867430140259 -0.469150025876993 0.639621633999661 CEP70 other 1 1 1 3.57244913397121 -0.469150025876993 0.603815236540773 133.309215103408 205.680592462187 0.648137062945871 0.517880644976881 -517.366295616976 841.328765380027 -0.614939506297853 0.539520258372987 RBP1 other 1 1 1 0.648137062945871 -0.614939506297853 7.52286258815053e-11 455.115762731591 62.9213321374256 7.23309166019528 2.03527677328811e-11 -52.3679995344542 248.169517681911 -0.21101705005357 0.833151140785489 SLC25A36 other 8.95145419364032e-07 1 2.69714877996141e-07 7.23309166019528 -0.21101705005357 3.80820046844307e-05 195.361878634436 51.5328198783347 3.79101859932509 0.000213977858388586 -409.535339311382 202.301181437576 -2.02438431847592 0.0446367650168609 RNF7 other 0.294069240173174 1 1 3.79101859932509 -2.02438431847592 1.95655985954916e-14 637.089349686625 72.4573228979427 8.79261507610454 2.53544438507185e-15 229.221666897714 284.444011809653 0.805858648383523 0.421551045449343 TFDP2 other 2.59635493362174e-10 1 3.54480479476895e-11 8.79261507610454 0.805858648383523 9.49173310434332e-08 153.781888583965 26.3447658362466 5.83728432204862 2.97788407087818e-08 -44.4088924453418 109.960062963301 -0.403863832454909 0.686865937919257 XRN1 other 0.000946041038509899 1 0.000355053117770805 5.83728432204862 -0.403863832454909 0.0513353129638161 70.5838852927891 30.1697007119088 2.33956199853609 0.020565532157925 23.4736113201863 60.3918476757213 0.388688411161548 0.698033263722907 KAT2B other 1 1 1 2.33956199853609 0.388688411161548 0.682186841340175 5.02776774726039 6.35482443887975 0.791173351147164 0.430100432191784 -12.3828713973043 34.3644215809234 -0.360339875593261 0.719103279110112 BCHE other 1 1 1 0.791173351147164 -0.360339875593261 0.364186504998887 11.4337133797316 17.8290711945322 0.641296075099983 0.522315560643791 130.399771505847 101.682167907278 1.28242517040702 0.201685089387344 SERPINI2 other 1 1 1 0.641296075099983 1.28242517040702 1.17100519116229e-07 262.333120476799 45.1328032379422 5.81247123281412 3.64517004191254e-08 371.071626223926 256.555223749233 1.44636160901805 0.150190291155763 PDCD10 other 0.00115847543561685 1 0.000433009749278791 5.81247123281412 1.44636160901805 0.715869535475983 -14.8285789169257 20.6754838414499 -0.717205896154053 0.474369885920522 -49.8120851709927 122.262594810793 -0.407418845052971 0.684285131301178 LRRC31 other 1 1 1 -0.717205896154053 -0.407418845052971 0.753620425047475 22.6735636673815 47.0199319455032 0.482211749979998 0.630340181700599 -28.4161199288909 105.793402695454 -0.268600113096769 0.788596908051986 WNT5A ts 1 1 1 0.482211749979998 -0.268600113096769 0.00616406974907968 145.677000559597 47.2785412916839 3.08124989857123 0.00256572139485358 27.1418527750926 106.103215876108 0.255806127561534 0.798545930997665 PFKFB4 other 1 1 1 3.08124989857123 0.255806127561534 0.286225727812426 14.9429407006409 11.5443834442372 1.29439053829247 0.197506556962473 -25.3886814759505 42.7332838722842 -0.59411959894842 0.553321179931591 FGF12 other 1 1 1 1.29439053829247 -0.59411959894842 1.16294992334306e-06 386.927421555253 89.7427821707341 4.31151578094749 3.22390797530508e-05 -279.125145859337 193.571712669237 -1.44197280692705 0.15177152307359 PRKAR2A other 0.0105502817045683 1 0.311397271334718 4.31151578094749 -1.44197280692705 0.662273803571116 11.4478647301104 68.1877766929029 0.167887344115473 0.866890762191766 232.716019943638 256.004568858021 0.909030729341009 0.364745195444877 HES1 other 1 1 1 0.167887344115473 0.909030729341009 2.37123061186442e-12 374.543111786653 60.6202236297237 6.17851748740505 7.84468195384434e-09 -289.794113582975 130.954650141245 -2.21293488448412 0.0286606551049941 USP4 other 2.97636866401222e-08 1 9.59012368857471e-05 6.17851748740505 -2.21293488448412 1.06671858062762e-09 361.776828242139 52.5921791476231 6.87890926190096 1.42287095691993e-10 203.792429267104 195.975354934025 1.03988804784005 0.30002179335574 ACAP2 other 1.20240518408346e-05 1 1.84560591822084e-06 6.87890926190096 1.03988804784005 2.50036769250525e-10 469.395866316141 67.8431528433367 6.91883921432822 1.25627170290946e-10 719.94365205014 369.507255285615 1.94838840578015 0.0532475877354134 ECT2 essential 2.9079276263836e-06 1 1.63189694207939e-06 6.91883921432822 1.94838840578015 0.000206040157968506 629.5160367812 405.101473260712 1.55397123519238 0.122549952046141 -2541.51511285143 868.492552881694 -2.9263522230773 0.00402994521173157 GNAI2 other 1 1 1 1.55397123519238 -2.9263522230773 9.82211734831401e-13 826.062656915182 117.918259260057 7.0053837471717 7.32799925228514e-11 -1309.7077587357 500.734961228573 -2.61557083116842 0.00979986846702698 TFG other 1.24740890323588e-08 1 9.58355742213851e-07 7.0053837471717 -2.61557083116842 0.145436475775495 6.06617354196307 12.1322784674011 0.500002827849907 0.617899344792056 -39.1663669985774 25.7038607655536 -1.52375424671866 0.129944385249896 HYAL1 other 1 1 1 0.500002827849907 -1.52375424671866 1.8783695306986e-06 86.5938502186319 54.9350477976651 1.57629516474749 0.117351436189992 -477.949486073627 118.260316828016 -4.04150351439275 8.97072037101845e-05 TUSC2 other 0.0167193671927482 1 1 1.57629516474749 -4.04150351439275 2.07210485947101e-07 37.450948890451 27.0374878459707 1.38514898661461 0.168325777861028 -269.185918146755 58.145409907859 -4.62952997619803 8.6087595200477e-06 NPRL2 other 0.00200932008222904 0.125076667066773 1 1.38514898661461 -4.62952997619803 0.00474647900216304 1106.97709196891 656.771946875831 1.68548169152876 0.0939208773698832 -7163.45988989639 2909.88790482448 -2.46176489411144 0.0149285885277496 RPL24 essential 1 1 1 1.68548169152876 -2.46176489411144 2.20036877281054e-07 31.6557133564614 13.7255203373428 2.30633976551958 0.0226147104376544 -120.230309518647 30.4515710294462 -3.94824652568454 0.000126154895087541 CYB561D2 other 0.00212687645579867 1 1 2.30633976551958 -3.94824652568454 0.146776697878239 -21.2869834702125 23.7430003222407 -0.896558277441979 0.371420568743871 -109.494429590947 55.6017002065975 -1.9692640545901 0.0508028401074455 C3orf14 other 1 1 1 -0.896558277441979 -1.9692640545901 2.67212741640633e-09 659.653983123016 98.3925032767096 6.70431141758705 3.98287277371267e-10 393.003974090991 460.061253340744 0.854242714936728 0.394351115001068 FXR1 other 2.94842539126274e-05 1 5.08573024475371e-06 6.70431141758705 0.854242714936728 0.000960169684929186 144.572887064519 44.9417119364296 3.21689763997017 0.001585650405805 -300.667603410168 210.305684192916 -1.42966940985942 0.154877646208663 CBLB other 1 1 1 3.21689763997017 -1.42966940985942 0.414170751456694 29.1887229212512 31.3348753891618 0.931509143047275 0.353160245933356 -139.354590658235 149.437400847172 -0.932528201562822 0.352635428091609 GNB4 other 1 1 1 0.931509143047275 -0.932528201562822 0.000659700922994853 97.1747783711897 29.2693690570607 3.32001616371529 0.00114972538765189 -148.254198200654 112.828877492076 -1.31397388236062 0.191019380174718 IQCG other 1 1 1 3.32001616371529 -1.31397388236062 0.11511281502255 19.1756583499541 26.4215215913479 0.725759047739078 0.469132592267729 -83.221651267857 61.3275619664376 -1.35700244065468 0.176846435052205 GBE1 other 1 1 1 0.725759047739078 -1.35700244065468 4.2169052179745e-10 153.604578192969 22.7593968656435 6.74906189736701 2.89398449343464e-10 -87.9535378691049 93.6134569850239 -0.939539471159318 0.348934748287158 UMPS essential 4.85323621536685e-06 1 3.71422995482263e-06 6.74906189736701 -0.939539471159318 3.3195504444323e-12 442.588047487969 56.4435458408876 7.8412516594122 8.84267311679322e-13 50.8754647574938 211.21549616287 0.240869944117468 0.809996165286448 NCBP2 essential 4.14545459500705e-08 1 1.20207298349687e-08 7.8412516594122 0.240869944117468 5.27431815350631e-14 221.645660269264 25.7626949928017 8.60335692097403 8.64873327421755e-15 39.9599629817332 105.779398484393 0.377766971208756 0.706127261952702 SNX4 other 6.93520094004544e-10 1 1.20390367177108e-10 8.60335692097403 0.377766971208756 7.09403609063294e-05 134.268319763139 77.33533904868 1.73618324319521 0.0845444512814725 -498.952863198977 184.454748039331 -2.70501501589206 0.00760462774414983 FRMD4B other 0.530562959218437 1 1 1.73618324319521 -2.70501501589206 1.64706169473205e-05 211.147714573998 44.1816207026008 4.77908485963641 4.07647507643652e-06 -22.8248798429009 181.999412686929 -0.12541183241159 0.90036109005135 SLC41A3 other 0.132934349381824 1 0.0427866824022777 4.77908485963641 -0.12541183241159 0.00494827293858597 401.841253328498 121.741113681131 3.30078509369493 0.00121190459871238 440.1533606294 513.159226953416 0.857732527275315 0.392446010622486 PLXNA1 other 1 1 1 3.30078509369493 0.857732527275315 1.2554938393433e-05 177.523245933479 38.6428099021084 4.59395283063495 9.46134591301631e-06 -178.811981702253 152.580462053149 -1.17191925687029 0.243178268381253 ABTB1 other 0.102674286181495 1 0.096269194664941 4.59395283063495 -1.17191925687029 0.00301801388291404 260.415465105416 77.3731270318152 3.36570945359795 0.000982227250754097 -112.608047086668 317.497172585517 -0.354674172905706 0.723359886705712 PODXL2 other 1 1 1 3.36570945359795 -0.354674172905706 0.0183934122574504 71.1215011124119 30.1377800639385 2.35987856310335 0.0198045487841301 -35.0992161020846 68.7937934789488 -0.510209051239849 0.610790614639004 CSPG5 other 1 1 1 2.35987856310335 -0.510209051239849 1.05207823781135e-08 89.3535098781001 17.0183981371517 5.25040659867032 5.702380770225e-07 -57.693838381435 38.2171298008319 -1.5096329494681 0.133456920539795 KLHL18 other 0.000111983207632641 1 0.00632736170264166 5.25040659867032 -1.5096329494681 2.0969441364681e-11 898.590302141351 137.175528948047 6.55066037676206 1.40320769196468e-09 -355.856091389003 315.523461462151 -1.12782767322579 0.261587900453809 SCAP essential 2.54904529229062e-07 1 1.76256918187683e-05 6.55066037676206 -1.12782767322579 0.629378898391522 3.70674403358764 7.62148955144046 0.486354276099095 0.627416480780208 -23.4320672869038 31.0980783710164 -0.753489235165818 0.452321524432697 EFCC1 other 1 1 1 0.486354276099095 -0.753489235165818 0.000164564844584753 14.14343101837 3.29291243578532 4.29511300229789 3.10093876217381e-05 9.89400638835032 13.4361201056285 0.736373767915758 0.462638213210948 KIAA1257 other 1 1 0.300170872178425 4.29511300229789 0.736373767915758 0.000285688845137044 80.1510464294622 19.6296694284561 4.08315823766607 7.159829035051e-05 -6.35424806717103 77.8194769902892 -0.0816536979291694 0.935029519922337 NEK11 other 1 1 0.665004920775537 4.08315823766607 -0.0816536979291694 1.61887141485956e-10 635.128579890266 98.613040817187 6.44061449304351 1.48054156895186e-09 -876.106638124533 390.93960745416 -2.24102808060261 0.0264732711634835 MRPL3 essential 1.89925994391324e-06 1 1.85867188566217e-05 6.44061449304351 -2.24102808060261 0.000352613204730698 138.369175727815 34.9737631872447 3.95637080822574 0.00011673054886957 -117.356955454226 148.761432280969 -0.788893691427841 0.431411014326892 PLSCR4 other 1 1 1 3.95637080822574 -0.788893691427841 3.02963343488108e-09 142.402732203844 30.9107966050843 4.6068929902771 9.29885341172348e-06 -176.511779280787 68.5158238121467 -2.5762191777003 0.0110555886018482 HEMK1 other 3.3347175217736e-05 1 0.0946809254381685 4.6068929902771 -2.5762191777003 0.483000806184358 -27.763637581196 40.0044032026874 -0.694014542362449 0.488856846521224 -105.446474251657 88.6724039035143 -1.18916900421911 0.236445269332768 CISH other 1 1 1 -0.694014542362449 -1.18916900421911 0.00090797414505893 30.6633906113482 52.2803854692188 0.586518066692564 0.558492598223 -372.372210013504 115.778015462614 -3.21626008638702 0.00162051013175386 MAPKAPK3 other 1 1 1 0.586518066692564 -3.21626008638702 8.13958836112525e-14 392.246629989086 48.9970009397944 8.00552324561788 2.55433050787954e-13 81.6012306000963 107.880515682862 0.756403786945001 0.450547913714976 ACVR2B other 1.06441396998435e-09 1 3.49560130003314e-09 8.00552324561788 0.756403786945001 2.44405349344733e-16 486.749407052127 59.6773601617697 8.1563495056195 1.03778309200492e-13 -120.716570916565 129.796146706958 -0.930047416500797 0.353774356265676 WDR48 other 3.34615363787875e-12 1 1.42674419488836e-09 8.1563495056195 -0.930047416500797 1.57260277356752e-09 227.922662915315 34.1008530965467 6.68378184762762 4.22222156512036e-10 253.956765778128 138.327860208891 1.83590467888843 0.0683386938873965 COMMD2 other 1.75675455835228e-05 1 5.38966582787614e-06 6.68378184762762 1.83590467888843 1.20555978755062e-06 116.982356506615 40.945313123093 2.85703900114119 0.0048558383504318 -262.316410161808 89.0546072192368 -2.94556809976188 0.00371446936747736 GORASP1 other 0.0109211661154211 1 1 2.85703900114119 -2.94556809976188 1.20460545418703e-08 94.843899985329 29.7037076588834 3.19299870152622 0.00173921652856947 -251.998190570006 68.1745380478913 -3.69636814250185 0.000313035969124164 RRP9 essential 0.000127820684743786 1 1 3.19299870152622 -3.69636814250185 7.96447096121909e-05 196.377601978904 44.7676193517094 4.38659917196168 2.19227172901278e-05 -122.477270605806 195.489776612304 -0.626514965274646 0.531955590391198 ABCC5 other 0.592078771257027 1 0.215193392919895 4.38659917196168 -0.626514965274646 0.727394061989074 6.46424574458735 13.0886078114744 0.493883370767695 0.622101475797757 -31.9943368587583 54.7909905921932 -0.58393426570603 0.560130099952399 AADAC other 1 1 1 0.493883370767695 -0.58393426570603 0.000885782948787998 288.521523979363 142.038608190846 2.03128943358625 0.0441045290417166 -649.623301526464 323.301019793479 -2.00934504302348 0.0464090641372838 ABHD14B other 1 1 1 2.03128943358625 -2.00934504302348 3.21375239840024e-09 187.951472310161 51.7327108465663 3.63312629928877 0.000378799736976346 -383.951929331781 112.083387425893 -3.42559176832196 0.000783016400980773 EIF1B other 3.53127113536219e-05 1 1 3.63312629928877 -3.42559176832196 0.0102993716795227 120.051977958713 143.363189851398 0.837397508266604 0.403796407086529 -747.322230446583 329.580927301388 -2.26749234722308 0.024891586743579 ABHD14A-ACY1 other 1 1 1 0.837397508266604 -2.26749234722308 0.000950367899807852 27.5001446049361 7.37023529823296 3.73124377881522 0.000269173010542337 -15.2372918257592 29.3999168304266 -0.518276698320105 0.605023823377598 ARHGEF26 other 1 1 1 3.73124377881522 -0.518276698320105 5.03301500354795e-18 696.688356758632 67.9177042163634 10.2578313680806 5.88889861913897e-19 428.55489617676 296.588376277286 1.44494838791691 0.150600677655826 KLHL24 other 7.01702951794655e-14 1 8.40345832951131e-15 10.2578313680806 1.44494838791691 0.005089350405716 55.9221430974544 18.0853277473799 3.09212771140163 0.00236489579422714 -76.9775428955927 72.5510772721918 -1.06101171464063 0.290367537372876 PLCH1 other 1 1 1 3.09212771140163 -1.06101171464063 0.0150773948959139 -9.22060721777013 20.3495750376018 -0.453110553941906 0.651098728980867 -129.412487226376 45.8951929989514 -2.81973947095794 0.00543038233846852 VIPR1 other 1 1 1 -0.453110553941906 -2.81973947095794 1.18121843450387e-05 124.396166604577 32.0442262845299 3.88201498454128 0.000158127051064735 -69.0610813548055 72.8798195137536 -0.94760225554308 0.344941798093355 DNAH1 other 0.0968773159353289 1 1 3.88201498454128 -0.94760225554308 0.000154784205380847 517.171870568987 119.971734164487 4.3107809866274 2.90125520097296e-05 12.0445337211421 470.523545863603 0.0255981530085502 0.979611215849534 SSR3 other 1 1 0.281421754494377 4.3107809866274 0.0255981530085502 6.77614710765951e-12 248.624691545912 36.7457639713169 6.76607762843043 2.55910158747534e-10 -63.2707221358614 81.0824549990857 -0.780325683732379 0.436389215694026 ZBTB47 other 8.37802828391021e-08 1 3.2904928211758e-06 6.76607762843043 -0.780325683732379 0.0991351685224022 13.4540728053248 29.3158934434968 0.458934428563675 0.646978058698409 138.460733256726 66.3714093203616 2.08615026672711 0.0387410535153927 TNNC1 other 1 1 1 0.458934428563675 2.08615026672711 9.67508661548378e-08 364.708940294722 75.6148438888146 4.82324529864792 3.33112573567838e-06 -200.457144064692 166.235640564733 -1.20586141084849 0.22969668089868 NKTR other 0.000963735377768339 1 0.0351700255172923 4.82324529864792 -1.20586141084849 0.000658876293163594 70.4489310237202 18.0180546083577 3.90990773171719 0.000150543997837793 69.5387894038703 73.3281696150456 0.948322994681735 0.344794836165505 CLCN2 other 1 1 1 3.90990773171719 0.948322994681735 0.136073869629083 52.4778979228197 44.2688926100424 1.18543507254833 0.237671432173694 -84.4028988658833 105.526370903353 -0.799827551571767 0.425042735901261 FOXP1 other 1 1 1 1.18543507254833 -0.799827551571767 2.41352800385902e-08 2401.98442719714 377.441310472384 6.36386203775882 3.52519671611264e-09 693.987933589532 1529.81767958082 0.453640942219787 0.650886642237396 EIF4G1 essential 0.000251103453521493 1 4.36701369192034e-05 6.36386203775882 0.453640942219787 1.09054445580452e-08 194.281009460617 124.044032981475 1.56622616010584 0.119475475768005 -1340.53928391285 282.753846808524 -4.741011657467 5.03117989099107e-06 SPCS1 other 0.000116001213763927 0.073183542694356 1 1.56622616010584 -4.741011657467 2.4915468801369e-15 188.011625787534 26.9393600148987 6.97906801362598 9.27745454708087e-11 -121.546487300392 61.2258406427143 -1.98521549111398 0.0489685404746399 NEK4 other 3.35960181317659e-11 1 1.21015117112123e-06 6.97906801362598 -1.98521549111398 0.00119010799173296 172.536198830409 53.3230801107021 3.2356757800227 0.00149327699413107 -57.9099649122808 131.671302663193 -0.439807032671431 0.660709893169195 SLC4A3 other 1 1 1 3.2356757800227 -0.439807032671431 1.22843096079147e-09 127.398328690808 25.5791781650258 4.98054815791535 1.67401577317792e-06 -166.628036817246 73.2993842908578 -2.27325288512728 0.0243844938083122 INO80D other 1.38038787064137e-05 1 0.0180375199559921 4.98054815791535 -2.27325288512728 0.0429487522826679 -370.769393252925 388.236668810728 -0.955008691962793 0.341069994228938 -2817.09078552624 1111.98800866328 -2.53338234187675 0.0122967001085362 EEF1B2 essential 1 1 1 -0.955008691962793 -2.53338234187675 0.0384187697819274 49.48430799826 19.2559598583838 2.56981777912853 0.011117767482011 45.1530482878628 54.4159578479322 0.829775861228888 0.407941655780685 ADAM23 other 1 1 1 2.56981777912853 0.829775861228888 1.40264735002141e-30 788.800039591768 53.3562991781539 14.783634767434 7.0473049100653e-31 54.9467094844276 272.668728874397 0.201514525377563 0.840574855972347 KANSL3 essential 2.03355812806104e-26 1 1.02326867294148e-26 14.783634767434 0.201514525377563 1.01506422362078e-11 215.117719514342 27.7478706324736 7.75258477897715 1.37251856125166e-12 152.349533696991 141.801000647841 1.07438969401455 0.28440843652558 LMAN2L other 1.24761543725231e-07 1 1.85935089492762e-08 7.75258477897715 1.07438969401455 2.97406069786345e-05 161.455278285934 46.7842891814883 3.4510576330359 0.000719696143101175 -243.207364141204 132.144725395765 -1.84046214037536 0.0676126767624841 TTL other 0.233196099319473 1 1 3.4510576330359 -1.84046214037536 0.193400618230698 -4.75092285624722 2.99109570756417 -1.58835534557875 0.114256997902894 -13.3560714726753 9.99803401893112 -1.33586977673668 0.183562640847456 IL1A other 1 1 1 -1.58835534557875 -1.33586977673668 0.584059086702822 -179.807584120582 183.70421088019 -0.978788582248942 0.329180754058825 -317.653641687011 418.081514466227 -0.759788774905694 0.44851302741783 CCL20 other 1 1 1 -0.978788582248942 -0.759788774905694 3.28751346665242e-12 199.464448481372 28.3912743528386 7.02555461239551 6.69458563575272e-11 -58.9243182373499 82.6258589200486 -0.713146211216598 0.476848727179398 PIKFYVE other 4.10709057388886e-08 1 8.76856826570892e-07 7.02555461239551 -0.713146211216598 2.80063498248604e-09 177.926616558609 27.4453615529909 6.48293942912984 1.50664556390434e-09 -10.2415801250791 94.3227422108641 -0.108580177855553 0.913694351764211 KCNIP3 other 3.08685987769611e-05 1 1.89038818903077e-05 6.48293942912984 -0.108580177855553 1.02864536489428e-05 68.1598508230453 15.736833269608 4.33123041054773 2.82122757569059e-05 -68.0787519290123 54.1323945605568 -1.25763422220042 0.210632845955348 FAHD2A other 0.0849352477793204 1 0.274025834426827 4.33123041054773 -1.25763422220042 3.33108492055325e-08 2270.18394346414 513.148193624811 4.42403183265219 1.81645453430732e-05 -2210.45442893512 1155.13777959588 -1.913585087407 0.0575164237818625 NCL essential 0.000343101746816985 1 0.179847163441768 4.42403183265219 -1.913585087407 2.71271820520262e-12 318.028501055595 46.2390476392027 6.87792065998266 1.56261777084322e-10 -584.221612783044 236.140251053281 -2.47404502272349 0.0144814076586298 ACTR1B other 3.39957845475993e-08 1 2.02437132212739e-06 6.87792065998266 -2.47404502272349 3.78030559095797e-16 373.294741045646 42.8429882912715 8.713088323993 4.53386156035479e-15 -249.023632528517 172.606702473807 -1.44272284308488 0.151142663960925 SLC35F5 other 5.1623853150122e-12 1 6.32519026285096e-11 8.713088323993 -1.44272284308488 0.737941791430338 -0.227068825565008 4.00723730007773 -0.056664681565178 0.954888224750017 -15.5462308283847 20.1471097567676 -0.771635783795864 0.441552226249271 ZAP70 other 1 1 1 -0.056664681565178 -0.771635783795864 6.680523651101e-13 1063.47249207152 156.173437058063 6.80956065323798 2.02880118860659e-10 -1694.43733623251 631.153999670963 -2.68466544950339 0.00805018888494069 ACTR3 other 8.5256842835351e-09 1 2.61979097484769e-06 6.80956065323798 -2.68466544950339 0.0465840477976472 -21.7367909400092 78.1168311515 -0.278260019250561 0.78118361609682 -519.260210405126 217.366839729036 -2.38886580424329 0.018103117891758 STEAP3 other 1 1 1 -0.278260019250561 -2.38886580424329 1.60534265279023e-08 336.418021547503 62.8291218397373 5.35449186136372 3.04196852642124e-07 -160.905119757813 167.589816645764 -0.960112750155457 0.338493779181428 EPB41L5 other 0.000169090741618395 1 0.00343438246632958 5.35449186136372 -0.960112750155457 0.373518038186602 -2.37137532847472 77.0253631472026 -0.0307869412305503 0.975479061432442 -262.036849276641 203.066710949899 -1.29039786014602 0.198834191221844 TFCP2L1 other 1 1 1 -0.0307869412305503 -1.29039786014602 8.2921791891323e-06 387.364396453931 90.1846718016331 4.29523541767679 3.08862761034614e-05 -458.819974884341 305.857865924976 -1.50010846867311 0.135647023127693 SF3B6 other 0.0690940069063616 1 0.29901003895761 4.29523541767679 -1.50010846867311 3.68321240477156e-05 156.201924288896 38.6248681928973 4.04407656509802 8.3035635962945e-05 -169.91436634315 130.99476353474 -1.2971080809508 0.196546571313481 TP53I3 other 0.285069341450395 1 0.765984152241498 4.04407656509802 -1.2971080809508 6.59867044798934e-10 37.7345116162878 5.70736615487563 6.61154560480623 6.17069280850388e-10 -8.73669516381234 18.7965618858075 -0.464802830267011 0.642742196074155 DNAJC27 other 7.51786524139426e-06 1 7.84233349032758e-06 6.61154560480623 -0.464802830267011 0.930315744836422 0.703472395703226 2.88447721966993 0.243882111776125 0.807653164020215 -2.07622061231854 9.4996979511137 -0.218556487059163 0.827290661489147 POMC other 1 1 1 0.243882111776125 -0.218556487059163 0.00306870205821155 85.8567912719394 30.2643377778346 2.83689641260944 0.00515670904951644 -96.8108194038024 86.7588979769647 -1.11586040926323 0.266186874964355 STAM2 other 1 1 1 2.83689641260944 -1.11586040926323 3.49873242049552e-05 9.75755777144667 2.32318587603922 4.20007622811578 4.54416467116438e-05 25.0940426978008 8.34476721792816 3.00715910251972 0.00308977938159705 OTOF other 0.271921483720912 1 0.431831968700751 4.20007622811578 3.00715910251972 2.8133050335018e-07 463.521786341082 103.22852628874 4.49024899420307 1.39280585106254e-05 -761.686759005567 336.87945917388 -2.26100683275089 0.0251687068548429 GPD2 other 0.00269148892555117 1 0.139308441223275 4.49024899420307 -2.26100683275089 0.000966224995567562 72.6504834976618 23.3505899922817 3.11129112890405 0.00223040374721373 -126.994899118394 85.3770286566589 -1.48745981344818 0.138992531190099 CENPA essential 1 1 1 3.11129112890405 -1.48745981344818 0.609065606597188 5.98137230952167 8.15234066578657 0.733699995465605 0.464247111582849 21.8371570771391 25.9053102908522 0.842960645209887 0.40055779537122 CYTIP other 1 1 1 0.733699995465605 0.842960645209887 0.00509004049269376 107.693796395271 43.0882937109323 2.4993748213322 0.0134897839696408 -194.967852352371 136.697269755587 -1.4262746629905 0.155813143080589 ACVR1 other 1 1 1 2.4993748213322 -1.4262746629905 1.2988263312711e-06 306.015541967887 64.6194311238999 4.73565824776667 4.91676740713868e-06 -279.298081623203 208.63541690207 -1.33868969022791 0.182644576430286 TANC1 other 0.0117284017713781 1 0.0512720505216421 4.73565824776667 -1.33868969022791 0.90186822454678 -1.18603497930614 7.47597639081149 -0.158646164367755 0.874174655083622 -12.5843775628922 28.1077964920038 -0.447718396085308 0.655043550774728 SLC30A3 other 1 1 1 -0.158646164367755 -0.447718396085308 6.17792140502944e-06 345.583418491728 71.1130347096064 4.85963536646882 3.1314028379683e-06 -189.000781453503 262.901058713873 -0.718904603800784 0.473406507344357 MPV17 other 0.052036631994563 1 0.0331239792200286 4.85963536646882 -0.718904603800784 2.02808889183344e-15 682.239086589175 74.8113827177717 9.11945564704963 8.87277395949983e-16 -128.542177906205 276.319320459372 -0.465194318271008 0.642536318838336 GTF3C2 essential 2.73954247508861e-11 1 1.24476145877823e-11 9.11945564704963 -0.465194318271008 3.71691858837522e-11 174.839527691875 23.5398020876159 7.42740007078721 1.16201946072657e-11 -29.02586449255 89.5908652383796 -0.32398241065447 0.746456487485121 EIF2B4 essential 4.47628505598027e-07 1 1.54780992168779e-07 7.42740007078721 -0.32398241065447 7.18145761791892e-07 528.004220101239 94.5790450577347 5.58267658315776 1.23834227364769e-07 152.894074730048 361.863228796877 0.422518958995612 0.673313522701253 NRBP1 essential 0.00662633094405379 1 0.00143214283947356 5.58267658315776 0.422518958995612 0.496108050402209 -7.2360946322634 10.4652328409026 -0.691441341274475 0.490449807598612 -43.4479879922806 40.2497634695761 -1.079459461299 0.282266001074038 FNDC4 other 1 1 1 -0.691441341274475 -1.079459461299 0.811827534963889 -2.2455483531614 13.72670919277 -0.163589708328939 0.870265891740205 24.8178266990516 45.5467274087603 0.544887154598911 0.586609250567834 ITGA4 other 1 1 1 -0.163589708328939 0.544887154598911 0.016859472204468 125.69378685643 62.6259284012827 2.00705666271377 0.0465644830589827 -260.645356089816 177.354706717832 -1.46962751039079 0.143785220177748 PSMD14 essential 1 1 1 2.00705666271377 -1.46962751039079 5.35225233110002e-08 563.966901886682 94.5361999903246 5.96561848206721 2.02252176868651e-08 -182.352830021554 361.123334389854 -0.504959975321597 0.614410269290256 SNX17 other 0.000543414179176585 1 0.000242985765289997 5.96561848206721 -0.504959975321597 3.21053658777367e-11 93.0573782384519 12.9711576564554 7.17417679308983 2.75940181437908e-11 -62.7514624125473 59.1633069077334 -1.06064832566593 0.290489107063623 ASB3 other 3.87351239314893e-07 1 3.64737731824626e-07 7.17417679308983 -1.06064832566593 6.607656916901e-12 877.589971655498 115.738472777944 7.58252593620486 4.90313048354378e-12 -414.957483244264 442.114906364313 -0.938573835152097 0.349625789050013 PPM1G other 8.17102854343977e-08 1 6.5804914219641e-08 7.58252593620486 -0.938573835152097 0.334547000393729 -47.1818209493656 41.3879638934911 -1.13998893665764 0.256049434119841 77.3704877733214 138.969329448649 0.556745060800704 0.578504589891993 PDE1A other 1 1 1 -1.13998893665764 0.556745060800704 0.112989147697281 58.8708724982713 90.3105721409194 0.651871326940659 0.5155529288786 -202.9367069684 135.74322811287 -1.49500427969533 0.137163996362823 REEP6 other 1 1 1 0.651871326940659 -1.49500427969533 0.00674274357663461 43.4245136695756 16.6870595588676 2.60228673100766 0.01025687694139 -13.1497580027283 25.0818401271768 -0.524274053899268 0.600917016599415 PCSK4 other 1 1 1 2.60228673100766 -0.524274053899268 0.0603758843917061 35.3354605422981 14.8507624743644 2.3793701234731 0.0186908855770226 18.6971483564741 22.3217547006804 0.837620008247121 0.403671818585645 APC2 other 1 1 1 2.3793701234731 0.837620008247121 0.072029936312314 50.4507600533737 84.0445119626492 0.600286192104904 0.549197857815368 -480.274181732555 241.963101128721 -1.98490670475022 0.0489310580187357 IFIH1 other 1 1 1 0.600286192104904 -1.98490670475022 0.0133425243191502 1989.76625306 1554.70490658213 1.2798353209255 0.20271981448916 -4284.59982621046 2336.83230854824 -1.8335076122224 0.0688509774704197 RPS15 essential 1 1 1 1.2798353209255 -1.8335076122224 0.0107887962850944 116.27503859135 38.1420314629303 3.04847524192193 0.00270795286866271 71.2313453337171 109.810432598161 0.648675573425524 0.517514222896235 GCA other 1 1 1 3.04847524192193 0.648675573425524 0.010490708205012 60.6293888166452 125.589832982345 0.482757141855331 0.630027619043468 -467.047368622351 188.43604552606 -2.47854579689616 0.0143888052085875 NDUFS7 other 1 1 1 0.482757141855331 -2.47854579689616 0.419306354031582 14.6037992144957 11.4573197440438 1.27462613776556 0.204324856289847 0.175211435593444 35.6671969545455 0.00491239711987276 0.996086726295211 GRB14 other 1 1 1 1.27462613776556 0.00491239711987276 0.00059910467126958 44.9688033049664 11.7630174778163 3.82289692162511 0.000191928191115703 -33.759230959758 74.0899449022513 -0.455651991701404 0.649290510993183 CLIP4 other 1 1 1 3.82289692162511 -0.455651991701404 1.28258829647216e-08 1306.038574631 216.725771738568 6.02622643423528 1.19032388971049e-08 -1031.89439908835 918.794310805066 -1.12309620004523 0.263144452745248 SPTBN1 other 0.000135954359426049 1 0.000144469610494162 6.02622643423528 -1.12309620004523 0.00298960852655393 509.613700544413 146.676410097042 3.47440805380531 0.000665105380075149 399.136115420287 621.824760596715 0.64187877471664 0.521906182269441 RTN4 other 1 1 1 3.47440805380531 0.64187877471664 4.78488409046747e-05 394.686594108559 105.860092976536 3.72837943941766 0.000268618596113525 -483.433068907059 321.933667154873 -1.50165427921676 0.135194982439431 GALNT3 other 0.365134504943572 1 1 3.72837943941766 -1.50165427921676 8.39427103608469e-05 167.006630152782 39.0341041619699 4.27847990208246 3.28133732701052e-05 -73.2607956183338 166.454068489265 -0.440126193869864 0.660458833171184 CCDC88A other 0.621679712932433 1 0.316386545070355 4.27847990208246 -0.440126193869864 5.97978065856176e-09 355.040788013319 54.7245502604256 6.48777900090061 1.12657849632215e-09 242.504994450611 158.241134727714 1.53250287839435 0.127450127142897 LANCL1 other 6.46175097964184e-05 1 1.41892561611775e-05 6.48777900090061 1.53250287839435 8.38649000443437e-11 227.679649548924 36.6295865144022 6.21573081256061 4.63100653517894e-09 -248.505638445524 133.588605309093 -1.8602308023992 0.0647725264335143 WDR75 essential 9.9606341782667e-07 1 5.71188346048971e-05 6.21573081256061 -1.8602308023992 0.000476659262496104 -15.9547917505737 133.155226534154 -0.119820995133686 0.904779122695738 2201.52311275904 566.192196290845 3.88829646042693 0.000149020488100005 EFEMP1 other 1 1 1 -0.119820995133686 3.88829646042693 0.095118087793244 3667.55786520434 5247.4549079829 0.698921273172814 0.485662314502588 30428.5653175413 14006.5613947505 2.17245078645396 0.0313610788359424 FN1 other 1 1 1 0.698921273172814 2.17245078645396 0.0867553960696998 705.567023845597 479.554425483905 1.4712970756836 0.14330558765844 -1997.92846321241 1714.54011349922 -1.16528534239705 0.245753223723911 STAT1 other 1 1 1 1.4712970756836 -1.16528534239705 0.0564664117092517 58.1734567391124 39.7786602372616 1.46242875934318 0.145715786500371 -200.62978266259 142.219746109569 -1.4107027199164 0.160402797661265 GLS other 1 1 1 1.46242875934318 -1.4107027199164 0.00406798351100691 -17.3043422814514 18.3456914462225 -0.943237398937856 0.347046533709156 -163.49505302982 48.9685110356552 -3.33877934149919 0.00105688671325537 PECR other 1 1 1 -0.943237398937856 -3.33877934149919 1.93613288179993e-09 111.129909611745 20.2750920423046 5.48110506131702 1.79298896709638e-07 -255.675634974363 94.8897084131256 -2.69445063379494 0.00787136229047615 UNC50 essential 2.15278615127334e-05 1 0.00205351026401549 5.48110506131702 -2.69445063379494 0.0298417738063086 4147.24144099997 1994.1664170931 2.07968673298862 0.039377991950419 -3816.86507231272 5515.85300422991 -0.691980926501432 0.490095355196487 IGFBP2 other 1 1 1 2.07968673298862 -0.691980926501432 0.23511757298062 2651.64987593047 1550.77188185091 1.70989035006594 0.0895174539823978 2796.2400124069 4338.21541363586 0.644559973582171 0.520274684858422 IGFBP5 other 1 1 1 1.70989035006594 0.644559973582171 0.236029560442798 112.271229809691 66.1612640198318 1.69693296331276 0.0916909276684205 134.81288981289 146.329961282272 0.921293825485498 0.358310559179246 EFHD1 other 1 1 1 1.69693296331276 0.921293825485498 1.9238592962833e-09 45.3201663201663 6.84073291522188 6.62504542741622 5.24803741542347e-10 26.1546546546546 15.1297620663162 1.72868909240043 0.0858306246307219 KCNJ13 other 2.13990869525591e-05 1 6.68337564854179e-06 6.62504542741622 1.72868909240043 7.16302536165671e-11 121.817079033988 17.7999454320402 6.84367710558906 1.80966529398033e-10 -104.281741188654 82.5532048995353 -1.26320645352971 0.208461977569116 TXNDC9 other 8.53116320573314e-07 1 2.34044012470476e-06 6.84367710558906 -1.26320645352971 0.0352704532090311 15.2813999465957 18.0301320096488 0.847547868114215 0.398058357089501 -129.64863508983 62.4924725207762 -2.07462802894743 0.039752681479353 COQ10B other 1 1 1 0.847547868114215 -2.07462802894743 1.85541768006373e-07 1138.36125458532 237.98868592712 4.78325786854391 4.06502110528031e-06 -1386.76872074883 824.770894300687 -1.68139871366903 0.0947526421468139 SF3B1 essential 0.00180606356977404 1 0.0426745915632327 4.78325786854391 -1.68139871366903 6.49976755791136e-19 164.640293285268 16.5345170625359 9.95736934212078 2.56705015195256e-18 -81.6253027868626 73.3010437092191 -1.11356262689335 0.267213232087349 CHST10 other 9.12437369779597e-15 1 3.65342577625888e-14 9.95736934212078 -1.11356262689335 5.75428466985212e-06 47.7352212068489 16.7542008119421 2.84914940095644 0.00499167858363138 -148.02701063062 47.8993207919824 -3.09037807182012 0.00237803365734183 PDCL3 other 0.0486237054602504 1 1 2.84914940095644 -3.09037807182012 0.000103365569893082 124.876560704711 35.6341084314301 3.50441097593359 0.000606795794630484 -178.545844504021 122.993502092311 -1.45166892125745 0.14872455589704 MOB4 other 0.75663597161736 1 1 3.50441097593359 -1.45166892125745 0.034697241549517 306.317541171965 169.206126633558 1.81032180847295 0.0722882724684025 -717.754346993487 584.026232343737 -1.22897621244356 0.221044427879686 HSPE1 essential 1 1 1 1.81032180847295 -1.22897621244356 8.38928900965628e-05 12.7142163963094 4.83482743093239 2.62971462331128 0.00944867492171505 -29.946706829914 12.7512029649282 -2.348539734822 0.0201698133774981 PLCD4 other 0.621394636945241 1 1 2.62971462331128 -2.348539734822 8.72561077118822e-10 237.043338834161 39.9316854750234 5.93622172503656 1.9895091347516e-08 -113.062413974504 105.314415767163 -1.0735701579969 0.284762659068491 ZNF142 other 9.88000907621642e-06 1 0.000239119102905794 5.93622172503656 -1.0735701579969 0.764172381353122 -13.1547674358577 19.1013152490946 -0.688683855761252 0.492072048416535 -25.2078364565588 52.8749065390008 -0.47674479458352 0.634228525977355 IL1R2 other 1 1 1 -0.688683855761252 -0.47674479458352 0.027892384780915 0.122970763856418 243.948047906641 0.000504085869559732 0.999598458652995 -1715.20613287904 675.279689656277 -2.5399936635916 0.0120892822915876 IL1R1 other 1 1 1 0.000504085869559732 -2.5399936635916 0.000172608973325911 207.786983122073 50.4384614427715 4.11961382600523 6.39511554273174e-05 346.390468571899 126.593495539688 2.7362422302598 0.00700282648173692 WNT6 other 1 1 0.59787935208999 4.11961382600523 2.7362422302598 0.00233736789372762 10.6850687453754 7.07977880622631 1.50923765245015 0.133313934402854 -48.8790459965928 19.597741716438 -2.49411624583227 0.0136973231016601 IL1RL2 other 1 1 1 1.50923765245015 -2.49411624583227 0.06589884422589 -3.8388828661401 5.87888003671606 -0.652995611777188 0.514745567240969 -38.1959114139693 16.2734988895643 -2.34712348421046 0.0202085766946687 IL18R1 other 1 1 1 -0.652995611777188 -2.34712348421046 0.057834046187737 51.2348618825816 24.4563117873777 2.09495455929805 0.0378226165117024 -29.2512578773009 67.4132445914192 -0.433909657584174 0.664965275790899 SLC9A2 other 1 1 1 2.09495455929805 -0.433909657584174 0.0164274814225561 -233.402829660911 128.739157020137 -1.81299019710376 0.0717681446231761 -981.004908595457 358.01745382682 -2.74010358464252 0.0068630429614691 FHL2 other 1 1 1 -1.81299019710376 -2.74010358464252 0.0267268966900155 44.5173588438796 104.128081479032 0.427525007774623 0.66959417661177 -493.25471737788 230.797349953466 -2.13717669408827 0.0341626505442908 MLPH other 1 1 1 0.427525007774623 -2.13717669408827 0.000172938895870011 219.065427970629 71.7832621745649 3.05176194748433 0.00272603148158578 -261.412837395292 179.341520427552 -1.45762585692416 0.147199288277294 CNPPD1 other 1 1 1 3.05176194748433 -1.45762585692416 0.0205228246471512 15.3967766596847 47.3212252319374 0.32536724449166 0.745341928888622 -328.863651337258 129.581990727685 -2.53788083892276 0.0121396459613198 UXS1 essential 1 1 1 0.32536724449166 -2.53788083892276 0.219705693818759 65.5554000482605 54.4600607769784 1.20373350879499 0.230738555522267 -87.9258540452966 136.061664048767 -0.646220628418761 0.519201991034838 ABCB6 other 1 1 1 1.20373350879499 -0.646220628418761 0.0251741732582752 63.7934640973491 39.166671249045 1.6287691055416 0.105626270042405 -129.595008445655 97.8530392615498 -1.32438409091477 0.187548998473402 STK16 other 1 1 1 1.6287691055416 -1.32438409091477 2.62010290817526e-11 4788.86097165992 755.61374197026 6.33771026870552 2.90031715194002e-09 -1421.11370040486 1616.76301514236 -0.878987017327168 0.380893297259136 HDLBP other 3.17425467325433e-07 1 3.60306399785509e-05 6.33771026870552 -0.878987017327168 0.000271871296046283 -1.21657986111109 52.4137787244746 -0.0232110695072441 0.981514041636148 -421.825985863096 113.321569001832 -3.72238038688183 0.000282368850537877 PPP1R7 essential 1 1 1 -0.0232110695072441 -3.72238038688183 0.000350712899505263 69.4211516203704 30.115786413194 2.30514158481203 0.0225874838607473 -128.175936259921 65.1120421217333 -1.96854425207987 0.0509256671063209 PASK other 1 1 1 2.30514158481203 -1.96854425207987 1.63122581954996e-10 568.868364343159 111.510250794803 5.10148941723723 1.06112225990782e-06 -529.815673460191 234.140492075263 -2.26281096774104 0.0251644972116337 STK25 other 1.91326476375015e-06 1 0.0115821494668939 5.10148941723723 -2.26281096774104 0.4400253323484 1.90952607509393 2.75968320919366 0.691936693578634 0.490046747518943 10.2379819595887 8.13707114425639 1.25819005119738 0.210277996065848 TPO other 1 1 1 0.691936693578634 1.25819005119738 0.129480082469897 4.07310032704039 3.0987340503584 1.31444011033128 0.190652442987839 -6.49567810908277 7.4385065132935 -0.873250308711058 0.383886273586566 PROC other 1 1 1 1.31444011033128 -0.873250308711058 0.447730907521168 6.27395239645146 91.2012383117742 0.0687924036185097 0.945244106118215 -328.132051255416 277.923179107356 -1.18065737557163 0.239559175951651 ID2 other 1 1 1 0.0687924036185097 -1.18065737557163 3.57497729759375e-11 75.8563669360633 12.4905660487239 6.07309281582266 9.51876072004697e-09 -84.6068728701806 39.6029938752105 -2.13637567747473 0.0342393298650454 TAF1B essential 4.30713264814095e-07 1 0.000115967061852332 6.07309281582266 -2.13637567747473 0.424730895545211 105.629302783496 102.804546166232 1.02747696208587 0.305828219817699 -136.692150720487 322.870757839985 -0.423364914292523 0.672627471227733 HPCAL1 other 1 1 1 1.02747696208587 -0.423364914292523 3.0326745960931e-09 1729.21806111892 311.518231412292 5.55093694927381 1.22428592367887e-07 -1626.5372310794 979.287027081704 -1.6609402413167 0.0987733214486237 ODC1 other 3.33776166046006e-05 1 0.00141637638510409 5.55093694927381 -1.6609402413167 1.92173601120429e-11 543.855802590615 71.5591086322414 7.60009190983099 2.83260219357504e-12 118.839303740022 290.278162924788 0.409398015140442 0.682823925433946 BIRC6 other 2.33875272563563e-07 1 3.81863101715851e-08 7.60009190983099 0.409398015140442 3.40709647615975e-15 258.042218571977 31.1742270982049 8.27742153026261 5.61738603007022e-14 -87.3228951875021 98.0901909067811 -0.890230657930806 0.374730667106966 NOL10 essential 4.58118192184441e-11 1 7.74188142664277e-10 8.27742153026261 -0.890230657930806 0.00147067435668143 305.512286682695 121.148334940896 2.52180343074251 0.0127054732935711 -426.474648248138 295.553052991566 -1.44297155428237 0.151086111528939 PLEKHB2 other 1 1 1 2.52180343074251 -1.44297155428237 4.85221677807423e-07 628.039211802215 140.710264648781 4.46335037013703 1.54462946667545e-05 -880.081526968134 434.967602607882 -2.02332661488243 0.0447579766186088 GORASP2 other 0.00454798278608897 1 0.153922326354208 4.46335037013703 -2.02332661488243 1.4809013895096e-05 159.478750659332 32.745174699194 4.87029774995391 2.75445018084119e-06 157.43112802351 130.758127858625 1.2039873207249 0.23045384453088 STRN other 0.120101102689228 1 0.0292550153707143 4.87029774995391 1.2039873207249 1.58496712005614e-11 308.043862810066 40.6836640624365 7.57168435805873 3.32048185779412e-12 -14.0953251478746 162.110863992929 -0.0869486769775616 0.930826744430253 CEBPZ essential 1.93492786016454e-07 1 4.47003267696244e-08 7.57168435805873 -0.0869486769775616 7.46388065804302e-10 308.309957748496 45.3961532578747 6.79154367986047 2.34786934215533e-10 -87.6601439415638 179.226954366604 -0.489101342213611 0.625474964920575 PRKD3 other 8.48195397980009e-06 1 3.02429049963028e-06 6.79154367986047 -0.489101342213611 1.14181677277695e-17 164.156790612561 19.1872475665705 8.5555153256357 1.06909902441972e-14 -153.704548455864 59.3121695528517 -2.59145044962318 0.0104701254429391 DCAF17 other 1.58655440577357e-13 1 1.48647528355317e-10 8.5555153256357 -2.59145044962318 0.250388651934989 -105.65730927146 71.6670617654122 -1.47427990863234 0.142474367675732 158.636398357681 282.946203297303 0.560659222527172 0.575855365081823 QPCT other 1 1 1 -1.47427990863234 0.560659222527172 1.762191598077e-10 222.002484326353 44.2379565538706 5.01837113692199 1.42226471419813e-06 -335.443532221606 110.248488499326 -3.04261343432076 0.00275816178232656 RAB3GAP1 other 2.06299770386874e-06 1 0.0153931710017664 5.01837113692199 -3.04261343432076 5.52432080712964e-05 58.4611560737261 23.2414423057317 2.51538417042684 0.0129091068474947 -209.791942573622 71.8446125171233 -2.92007897632715 0.00402174754992999 SLC25A12 other 0.418301571515857 1 1 2.51538417042684 -2.92007897632715 0.0039898038089784 11.669365980964 3.7524467903623 3.10980185273656 0.0022334012621012 -12.8352631019579 14.8339015027759 -0.865265493340107 0.38824776556135 RMDN2 other 1 1 1 3.10980185273656 -0.865265493340107 0.446380832239072 52.0018604651164 42.1946444707353 1.23242798031355 0.219655390600803 2.80790697674423 132.925156851835 0.021123969632581 0.983173932769865 DLX2 other 1 1 1 1.23242798031355 0.021123969632581 9.54822819664089e-10 398.881259550107 95.9198847321611 4.15848351636276 5.30335381601982e-05 -901.387524971884 241.416963134117 -3.73373732015313 0.000265048981170004 DARS essential 1.07885430393845e-05 1 0.50026536546515 4.15848351636276 -3.73373732015313 0.000244298097877821 258.497162488711 74.0735562791369 3.48973608766125 0.000632857210616174 -513.115422636628 289.279328362167 -1.77377148080981 0.0781032602809199 SRSF7 essential 1 1 1 3.48973608766125 -1.77377148080981 0.36186399722497 320.653831119053 234.822676234748 1.36551476314196 0.174149232726002 -35.8193462247245 781.90941723206 -0.0458100969694471 0.963522950750645 SDC1 other 1 1 1 1.36551476314196 -0.0458100969694471 0.0996251285313797 10.5319086470116 5.77797118777613 1.82276932589987 0.070303404121195 -10.0839050621176 19.1739564115301 -0.52591676155338 0.599712500971545 PLCL1 other 1 1 1 1.82276932589987 -0.52591676155338 1.13966228956709e-07 559.986050428372 94.8255576868233 5.90543376794911 2.21648700536427e-08 19.1906319412239 370.322082766508 0.0518214625437928 0.958738994289319 SOS1 other 0.00112849359912933 1 0.00026584545142339 5.90543376794911 0.0518214625437928 0.0981806087927386 -25.9572327729861 11.9593555914143 -2.17045413313247 0.0314848866855306 -18.6333059577644 31.9963495598921 -0.582357244312692 0.561166809089617 KYNU other 1 1 1 -2.17045413313247 -0.582357244312692 0.941785342061648 7.44583814422173 50.9233584526895 0.14621655700771 0.883942907027189 -46.1858927259369 177.428703795553 -0.260306769637205 0.794977142719075 WIPF1 other 1 1 1 0.14621655700771 -0.260306769637205 3.83120197228394e-12 123.400110497237 18.9484656540763 6.51240647923867 1.00520432978147e-09 -108.878563535912 56.1815148491843 -1.93797842276395 0.0544671914749583 ORC2 other 4.77559325845193e-08 1 1.26836682331826e-05 6.51240647923867 -1.93797842276395 0.000192595792697389 408.890231237219 101.210072709524 4.04001519108425 8.43449081994548e-05 -166.831697513254 454.946230135906 -0.366706407180067 0.714344670775221 COX7A2L other 1 1 0.777491363782574 4.04001519108425 -0.366706407180067 8.67896965286853e-06 186.964480678578 44.2087645247756 4.22912702239844 3.99728030892612e-05 -147.31581247403 123.00580628876 -1.19763299732536 0.232888175688423 ORC4 essential 0.0721395957546432 1 0.381460459880819 4.22912702239844 -1.19763299732536 0.421619358621478 30.5114561706256 71.5866034329241 0.426217402523009 0.670533222693029 -224.201849704749 213.859778965547 -1.04835912011706 0.296084361435195 RND3 other 1 1 1 0.426217402523009 -1.04835912011706 6.43746101421755e-11 345.281372533069 50.41392626739 6.84892842310543 1.72930608822005e-10 -141.710403006687 175.637335222956 -0.806835305413842 0.421022034650841 ATF2 other 7.68310972046865e-07 1 2.23720328633028e-06 6.84892842310543 -0.806835305413842 1.65989009421239e-14 276.219702658056 32.7396472545376 8.4368564056466 2.45205743338377e-14 -109.673865854824 143.644026376123 -0.763511498679728 0.446349690521579 THADA other 2.20516399016116e-10 1 3.3953639280065e-10 8.4368564056466 -0.763511498679728 0.0055974782010368 134.447335756716 52.1242577317389 2.5793621167453 0.0108277232456473 -142.450416703608 153.346983609513 -0.928941759078532 0.354363661267277 TRAK2 other 1 1 1 2.5793621167453 -0.928941759078532 0.180800968907136 11.0403207799941 6.84510960703301 1.61287713620402 0.109039312283433 -1.02130470378089 10.2366235740224 -0.0997696844468007 0.920670925995005 KISS1R other 1 1 1 1.61287713620402 -0.0997696844468007 0.287718989322442 87.3255014513248 56.274633439617 1.55177379422694 0.122990260821144 34.5371715912473 84.1567589649077 0.410390942047197 0.682151075146286 ARID3A other 1 1 1 1.55177379422694 0.410390942047197 0.000918265340838062 237.908096807032 92.2356150744864 2.57935176791422 0.0108280340249941 -458.544955504231 273.056842809541 -1.67930219505273 0.0951078296496897 SUMO1 other 1 1 1 2.57935176791422 -1.67930219505273 0.42517703963707 2.35290916195298 7.09918149810921 0.331433864957481 0.740815952582676 -10.433932159869 10.6165792590292 -0.982796049960739 0.327415378250377 GRIN3B other 1 1 1 0.331433864957481 -0.982796049960739 6.11624177946151e-08 596.299437944484 113.710211852132 5.24402714788633 5.45563223093741e-07 -708.523885447731 416.796054807755 -1.69992944336897 0.0912882668172877 NFE2L2 other 0.000618719018410326 1 0.00606229853501765 5.24402714788633 -1.69992944336897 7.053589874406e-11 150.067206385405 22.6936162742656 6.61274979587892 6.22895072765055e-10 -137.503610794375 87.9266214925787 -1.56384503874041 0.119961248604816 PLEKHA3 other 8.40435233535474e-07 1 7.91575058469833e-06 6.61274979587892 -1.56384503874041 0.0153197421341179 131.123525247758 51.511055678643 2.54554140893142 0.0119001310245461 -32.4663363221653 121.079714260681 -0.268140179553663 0.788952591243493 EPHA4 other 1 1 1 2.54554140893142 -0.268140179553663 0.00214555688925863 54.7931868848893 24.9001782621644 2.20051384002126 0.0292403259477408 -127.420031537165 74.7094911482287 -1.7055400803675 0.0900840458203027 PARD3B other 1 1 1 2.20051384002126 -1.7055400803675 5.28579021115361e-05 139.367473496883 46.4466240695713 3.00059425822053 0.00314703869271604 -200.407490201216 108.403531307129 -1.8487173598932 0.066428671206352 FARSB essential 0.401508624439228 1 1 3.00059425822053 -1.8487173598932 0.00158976718805736 2206.75776627907 1316.95988222576 1.67564539821022 0.095836860336502 -9621.50693447576 3815.57567462669 -2.52163965675169 0.0126975534222301 DHCR24 other 1 1 1 1.67564539821022 -2.52163965675169 1.1595178970461e-19 213.272147693739 26.0765583318569 8.17869233276814 9.955773067075e-14 -63.9766522531099 60.7143474360867 -1.05373202471553 0.293656083763068 DNAJC16 other 1.63515213841441e-15 1 1.36881923899214e-09 8.17869233276814 -1.05373202471553 0.382536857397248 -11.7740560700223 10.1620765026764 -1.15862698602214 0.248390240393617 -35.436634811637 31.0934720334218 -1.13968085563255 0.25617741496869 MARK1 other 1 1 1 -1.15862698602214 -1.13968085563255 1.78078746440925e-14 135.94845412317 17.5723942661422 7.73647870996786 2.06199141927703e-12 15.5690704760001 39.2913020862458 0.396247251919151 0.69254363842689 MORN1 other 2.36435151649617e-10 1 2.7859566065852e-08 7.73647870996786 0.396247251919151 0.380404698781965 39.7844384634203 61.3603368107483 0.648373860562828 0.517721463559087 -182.104355272816 190.588989730065 -0.955482032465433 0.340851124067619 GPX7 other 1 1 1 0.648373860562828 -0.955482032465433 1.68962988270937e-06 84.0214526509349 112.758490232537 0.745145243410591 0.457334551412709 -1679.41142098273 350.182958696343 -4.79581138738111 3.83029664825787e-06 SCP2 other 0.0150968430020083 0.0557499677153933 1 0.745145243410591 -4.79581138738111 2.86249028638124e-14 186.972278589188 36.2352730800318 5.15995224256288 7.98710933552924e-07 -247.608334183234 81.0392731167441 -3.05541158823738 0.00267576644522002 CEP104 other 3.78363966053873e-10 1 0.00877543702694597 5.15995224256288 -3.05541158823738 1.40405502519372e-05 268.155994112568 414.42191843455 0.647060356087121 0.518568852660014 -5498.60637500808 1269.63289171758 -4.33086320532345 2.68492329911577e-05 TMEM59 other 0.114191795199006 0.388078813654194 1 0.647060356087121 -4.33086320532345 2.53992416795736e-09 201.617834201109 45.7737640390961 4.40465927226137 1.98909456483758e-05 -451.709503942069 140.233597251044 -3.2211218480934 0.00156195900571932 LRRC42 other 2.80636221317608e-05 1 0.196263960712524 4.40465927226137 -3.2211218480934 9.61551436942995e-13 131.619772227007 22.2126743657942 5.9254356346074 2.3336746086353e-08 -79.6400574217628 49.4786467914103 -1.60958438814031 0.109757389229275 WRAP73 other 1.22165110063607e-08 1 0.000279574218114509 5.9254356346074 -1.60958438814031 8.73603280725737e-06 318.908285388677 121.684399197931 2.62078201881856 0.00967585222547473 -1138.55365923869 369.59550463829 -3.08053979269297 0.00245857709644443 MRPL37 other 0.072605168661116 1 1 2.62078201881856 -3.08053979269297 9.19225332338696e-11 497.904488126115 98.3682313891065 5.06163911961168 1.24118087312032e-06 -349.677512086316 224.203310057622 -1.55964473493477 0.121023803819201 ICMT other 1.09029316668693e-06 1 0.0134792242820867 5.06163911961168 -1.55964473493477 1.6107928654306e-06 1380.56172672421 350.080880396561 3.94355077363936 0.000124556875726311 -656.600060303092 797.91301586304 -0.822896791065502 0.411917956483464 RPL22 other 0.0144230393170656 1 1 3.94355077363936 -0.822896791065502 4.6984253804664e-08 163.120144965789 38.5773067342292 4.22839640127221 4.0483175179964e-05 -357.253619068889 121.37601260934 -2.94336262486019 0.00375644283467531 STXBP3 other 0.000478722562015721 1 0.386209491216857 4.22839640127221 -2.94336262486019 1.26570823578283e-13 180.399790161778 28.3786448873086 6.3568852874457 2.44468199675811e-09 -79.4047750282847 63.9863610684252 -1.24096406956744 0.216595791020148 PHF13 other 1.64719269804777e-09 1 3.04558483156125e-05 6.3568852874457 -1.24096406956744 0.393124468462236 69.2047648136841 122.630615479865 0.564335133953943 0.57335244043407 -190.93554062309 268.230069262506 -0.711834959995591 0.477650958000502 ERRFI1 other 1 1 1 0.564335133953943 -0.711834959995591 1.02801648161897e-06 301.294746487478 136.336088621288 2.20994125278458 0.0285943821378428 -866.153634697618 298.208064525874 -2.90452787074934 0.00422326751596951 PARK7 other 0.0093713982464385 1 1 2.20994125278458 -2.90452787074934 0.317789054340266 -101.004995568448 359.44764156912 -0.281000579465549 0.77909978134539 -1732.19474659576 1148.96737488439 -1.50761003703004 0.133771703293005 KIAA1324 other 1 1 1 -0.281000579465549 -1.50761003703004 4.67203414716405e-07 373.875641938949 84.0583407076414 4.44781135092001 1.67303654201957e-05 -523.666989186718 281.071171680902 -1.86311170247383 0.0643889700119523 AMPD2 other 0.00438657286077233 1 0.166232910815064 4.44781135092001 -1.86311170247383 1.66282719014865e-12 287.539956013559 69.9847652132556 4.10860785397187 6.4856488407434e-05 -547.40739823356 161.813822971247 -3.3829458335635 0.000912127812243569 SRSF4 other 2.09665880405844e-08 1 0.605889314702248 4.10860785397187 -3.3829458335635 2.89055190474717e-10 50.4601586903145 22.2697798554293 2.26585799311404 0.0248720453552844 -220.387368277564 51.4906094798549 -4.28014681713542 3.2928805100172e-05 MECR other 3.35275115431624e-06 0.475096799985282 1 2.26585799311404 -4.28014681713542 0.000683135861917162 77.2761548913044 35.9310208735607 2.15068074918425 0.0330718030004719 -316.506184895833 124.429684802673 -2.54365495980935 0.0119619026761979 KCNC4 other 1 1 1 2.15068074918425 -2.54365495980935 1.85006105659968e-07 167.26656394453 31.9272153157363 5.23899633245145 5.19466937213063e-07 -245.883667180278 134.693399025612 -1.82550643876411 0.0698494184025249 EDEM3 other 0.00180103443859979 1 0.00578270594505582 5.23899633245145 -1.82550643876411 5.30170082645847e-07 423.775670570458 99.6765445432764 4.25150844175249 3.66780087981789e-05 -717.719795995467 322.462664241016 -2.22574541361175 0.0274836676407793 WDR77 essential 0.00495125840182956 1 0.351595392339343 4.25150844175249 -2.22574541361175 0.000302477787442844 136.571609369097 187.694827427291 0.72762585544347 0.467947442008474 -2217.56751038912 607.209794378296 -3.65206149656993 0.000355983735048432 ATP5F1 essential 1 1 1 0.72762585544347 -3.65206149656993 0.000810154732883397 -13.131299584435 48.3518641007775 -0.271577938692624 0.786310284923018 -586.737268605969 156.422666841012 -3.75097343917763 0.000248902627184313 RAP1A other 1 1 1 -0.271577938692624 -3.75097343917763 3.69108272378987e-13 591.556102362205 106.535734778423 5.55265426753329 1.24613946648028e-07 -896.999015748032 299.795394010849 -2.99203734836424 0.00324109231399525 HDAC1 other 4.74599416624901e-09 1 0.00144066183719786 5.55265426753329 -2.99203734836424 2.0407205714461e-05 -2.5313938016295 117.767408605607 -0.0214948586506385 0.982879282292361 -1790.18238897821 392.580514998784 -4.56003882154915 1.05028824229997e-05 CAPZA1 other 0.16317601689283 0.152501852781955 1 -0.0214948586506385 -4.56003882154915 1.44981357287231e-14 167.252529224473 26.1035481964784 6.4072718377434 1.8352154768865e-09 -189.375768311585 73.4688649490078 -2.57763296660462 0.0109179859871788 S100PBP other 1.92767212649103e-10 1 2.29695569087115e-05 6.4072718377434 -2.57763296660462 1.08029496797898e-06 235.41957801094 60.6755765107553 3.87997266032092 0.000155606587439779 -288.312832630265 171.62828162153 -1.67986785106923 0.0950508096733429 RNF19B other 0.0098306842086087 1 1 3.87997266032092 -1.67986785106923 1.45465251280743e-06 90.4428016177318 23.8882019809329 3.78608660835678 0.000219820128524988 -122.757887944295 68.1195380825852 -1.80209513158278 0.0735120227152302 TRIM62 other 0.0130773260901388 1 1 3.78608660835678 -1.80209513158278 0.369430180383722 33.6707399864224 43.3932352748588 0.775944447864908 0.439011684030903 -97.2393383941244 128.017372920643 -0.759579236596291 0.448706219027266 DLGAP3 other 1 1 1 0.775944447864908 -0.759579236596291 4.10300606726327e-07 868.16940836941 205.953728711592 4.21536144939213 4.33612640223404e-05 -1054.4387012987 632.074850651537 -1.66821809191079 0.097401150024096 SFPQ other 0.00387241712628307 1 0.412582427172569 4.21536144939213 -1.66821809191079 0.000221947001673298 291.358835451884 77.4901645295378 3.75994601664348 0.000239854469465585 -94.7244388676105 245.155066700247 -0.386385809367875 0.699737452237011 RHOU other 1 1 1 3.75994601664348 -0.386385809367875 3.98848083554594e-12 325.63575098735 46.6691387459827 6.97753932764359 7.7946766058608e-11 -232.020968641853 147.560556946332 -1.57237796768576 0.117863288287184 DOCK7 other 4.96964712109024e-08 1 1.01868628561995e-06 6.97753932764359 -1.57237796768576 3.70735481011435e-06 358.851521505258 136.43151129666 2.63026860946342 0.00939242349362171 -701.167074670122 312.244977321729 -2.24556718472899 0.0261458790421657 SRM other 0.0319722278824262 1 1 2.63026860946342 -2.24556718472899 0.0196205059717736 49.017921441607 67.3842519354401 0.727438830790469 0.468061637551312 -290.559168160121 154.594485014134 -1.87949245494466 0.0620664620301838 FBXO2 other 1 1 1 0.727438830790469 -1.87949245494466 0.0313910056223724 18.0250160306473 36.4323285831721 0.494753333965397 0.621479348944552 -158.792377084669 83.5838777371511 -1.89979672376566 0.0593290735249709 FBXO6 other 1 1 1 0.494753333965397 -1.89979672376566 0.594795124128014 17.5451728879834 78.0070194659954 0.224917872879781 0.822339411605707 -313.36528488825 329.093235843632 -0.952208221736725 0.342473900430509 C1orf21 other 1 1 1 0.224917872879781 -0.952208221736725 2.68890136984302e-12 50.0924593460756 6.59223245733944 7.59870949185134 2.6574116579255e-12 -36.0325890759835 27.8738254060673 -1.29270340726681 0.198037297344283 SWT1 other 3.37026897696124e-08 1 3.58564555003888e-08 7.59870949185134 -1.29270340726681 0.00213447086324022 284.645689811085 103.055243037549 2.76206897796915 0.00644298532794507 -84.7299288074843 236.431684967881 -0.358369601853469 0.72055751324894 MAD2L2 essential 1 1 1 2.76206897796915 -0.358369601853469 0.051368631871313 -3.41794301911706 10.2626959698539 -0.333045335178698 0.73954723255916 -80.3680082459618 32.9674022284616 -2.43780227780817 0.0159002533398736 DNAJC6 other 1 1 1 -0.333045335178698 -2.43780227780817 0.28297851746665 -26.5870531417872 42.2799441890412 -0.628833685846693 0.530377634055852 -206.558723687203 130.541715031292 -1.58231967182053 0.115601908940085 LEPR other 1 1 1 -0.628833685846693 -1.58231967182053 4.31711862966511e-07 753.17917398149 132.742252389023 5.67399724222076 6.66705129940545e-08 312.61914299137 561.27182878394 0.55698349170436 0.578342072995651 IVNS1ABP other 0.00406802088473343 1 0.000781845105881277 5.67399724222076 0.55698349170436 2.5250965050741e-18 646.065286202713 82.8829141936762 7.79491518231397 8.98300749854377e-13 -253.033572295137 190.970610495189 -1.32498697909075 0.187138072823749 MFN2 essential 3.53210499129765e-14 1 1.22097037920207e-08 7.79491518231397 -1.32498697909075 7.00573457194595e-14 232.364423182971 39.731441312842 5.84837638668463 2.87585838491774e-08 -185.79091209882 91.5452560661303 -2.02949797818697 0.0441295803542283 MIIP other 9.17891343616358e-10 1 0.000343118663904536 5.84837638668463 -2.02949797818697 0.000628499057832513 42.4300928052129 25.7410072042423 1.64834625422972 0.101281360414161 -237.514237064895 79.5288778977108 -2.9865156323516 0.00327480135717759 SLC35D1 other 1 1 1 1.64834625422972 -2.9865156323516 0.0668914386034298 -55.8000691169294 73.5270949714511 -0.758904851858968 0.449047322729361 -520.534314522686 221.979782416354 -2.34496272073261 0.0202802500393488 GADD45A other 1 1 1 -0.758904851858968 -2.34496272073261 7.64931430534725e-08 1527.5796674256 258.128409883028 5.9179060070057 1.97903361393401e-08 474.758416002601 779.294874679355 0.609215370751595 0.543262261185387 WLS other 0.000768655587213128 1 0.000237879840394868 5.9179060070057 0.609215370751595 1.59478321076655e-15 363.061223476185 53.3165858012081 6.80953624506013 2.02906607749471e-10 -193.018586705978 133.72322719226 -1.4434185500808 0.150920632122282 PRDM2 other 2.15837959745144e-11 1 2.61993011926118e-06 6.80953624506013 -1.4434185500808 0.189994159323344 -70.2724318469038 38.487936106786 -1.82583009002953 0.0699191037776449 -68.3924896190647 152.847137421889 -0.447456790965522 0.655208440250191 RGS2 other 1 1 1 -1.82583009002953 -0.447456790965522 1.22021172890033e-08 176.332181399297 28.643497036821 6.15609822964785 6.93038967066418e-09 -100.802170486238 113.761618017756 -0.886082426064868 0.377040285444038 TROVE2 other 0.000129452262319036 1 8.49873685313548e-05 6.15609822964785 -0.886082426064868 0.000281138816272431 59.7754941190737 23.7350705773365 2.51844602375653 0.0128730231904038 -270.873893537044 94.2671221035763 -2.87347155076423 0.00467051724481084 UCHL5 other 1 1 1 2.51844602375653 -2.87347155076423 5.91366007724162e-07 106.086297760211 33.5410076987556 3.16288343847661 0.00188433707705793 -373.067903111382 111.033299383714 -3.35996412951862 0.000984257623892199 BCAS2 essential 0.0055020693358656 1 1 3.16288343847661 -3.35996412951862 1.45137130831614e-08 608.004069050555 136.205486511228 4.46387355329064 1.53536760364707e-05 -1235.00049321825 411.026578797148 -3.00467307207341 0.00309851452806818 SRSF11 essential 0.00015329383758435 1 0.153030089055504 4.46387355329064 -3.00467307207341 5.53460318528772e-06 25.3893958076449 5.41440580001931 4.68923031361157 5.94492969171985e-06 -9.02901767365393 16.339023847016 -0.552604473693996 0.581325208554008 CTH other 0.0468448813602752 1 0.0615716368171425 4.68923031361157 -0.552604473693996 0.000129501116524842 35.3599605795689 9.85265597498944 3.58887600148922 0.000445772379083772 1.44421067784319 22.9400509998648 0.0629558616871296 0.949883290576298 AGMAT other 0.935257063542406 1 1 3.58887600148922 0.0629558616871296 0.612778981878504 67.0770327218648 107.001324082783 0.626880398881508 0.531671930386159 -181.071426528355 348.59728895841 -0.519428671030079 0.604212452643109 OLFML3 other 1 1 1 0.626880398881508 -0.519428671030079 0.712994055823839 0.386107712086237 3.26388920691951 0.118296819410316 0.905984662132912 -7.0853688759468 9.64361626708854 -0.734721154358614 0.463612340008652 TNNI3K other 1 1 1 0.118296819410316 -0.734721154358614 0.71126783042225 -1.06365674365257 2.87344459597823 -0.37016782754096 0.711783098164477 -8.91967050727282 11.1629729843795 -0.79904076806011 0.425538648175173 CFHR3 other 1 1 1 -0.37016782754096 -0.79904076806011 5.62495432420897e-19 649.956196854365 84.8907164579095 7.6563872231733 1.96678877826119e-12 -262.478978291218 198.297358762041 -1.32366351185845 0.187576402211057 PLEKHM2 other 7.89968585291908e-15 1 2.65850839157565e-08 7.6563872231733 -1.32366351185845 0.00953283318416165 18.8580894533405 47.7414945072257 0.395004170857834 0.69337594479216 -393.376096693049 141.133655295474 -2.78725932428723 0.00597209163751715 CRYZ other 1 1 1 0.395004170857834 -2.78725932428723 6.25933973983277e-05 39.7275413381529 22.3031583054923 1.78125182066119 0.0768683707579736 -237.226645276256 70.7652616890768 -3.35230365314785 0.00101143318596116 PHTF1 other 0.470764941832823 1 1 1.78125182066119 -3.35230365314785 6.76277448023787e-21 179.320116206376 20.8217013791832 8.61217404576045 8.50994545540594e-15 -53.4248078549625 46.4920126919632 -1.14911798310245 0.252312324744352 ZBTB17 essential 9.6038160393858e-17 1 1.18466950684706e-10 8.61217404576045 -1.14911798310245 0.131541572302494 -31.1468671363866 18.4771119365621 -1.68569997537082 0.0939189309929368 -100.450176144942 63.8959206736408 -1.57209059805255 0.118022560241018 CD58 other 1 1 1 -1.68569997537082 -1.57209059805255 0.0240562891720887 6.73439728906719 3.10008432537252 2.17232713121697 0.0314121627725998 -8.09052163331372 10.5334907896696 -0.768076015336558 0.443657593580424 TFAP2E other 1 1 1 2.17232713121697 -0.768076015336558 0.808984508191123 -7.5709558589016 18.8617812440801 -0.401391351162966 0.688695762414971 -40.5655976908849 66.6561153362778 -0.608580285338154 0.543711067295242 CD2 other 1 1 1 -0.401391351162966 -0.608580285338154 7.665371298759e-17 199.874547552157 22.198722050455 9.00387630863915 9.15340871799609e-16 -191.469588753167 96.6836972481758 -1.98037098500368 0.0494910202645897 TTF2 essential 1.05613485754301e-12 1 1.28404017496049e-11 9.00387630863915 -1.98037098500368 0.0465873320331186 33.9824522114693 18.7854369705971 1.80897853292732 0.0724048703793278 140.355290730225 67.3822229865833 2.08297210316394 0.0389066292097974 NR5A2 other 1 1 1 1.80897853292732 2.08297210316394 0.310665096240214 11.140338672226 7.54336798795287 1.47683881921414 0.141747695897665 -3.12580231651074 29.9121025275591 -0.10449958553167 0.916907996359364 KIF21B other 1 1 1 1.47683881921414 -0.10449958553167 0.00237300408666481 175.357110555314 92.2806414694747 1.90025890330769 0.0592679600520081 -925.38305815252 365.388626144033 -2.53259951717201 0.012323066520139 TMEM9 other 1 1 1 1.90025890330769 -2.53259951717201 4.04580002019764e-08 165.78118933812 41.6600619375785 3.97937932945272 0.000109436920971267 -429.525002261231 148.385362751567 -2.8946588416565 0.00439133988322804 ADPRHL2 other 0.000414330380068441 1 0.995985417759496 3.97937932945272 -2.8946588416565 2.8838709907694e-05 435.537949496106 136.740439445227 3.18514370191538 0.00176916140968549 -1058.29433405864 501.223733121182 -2.11142103640725 0.0364395837894316 MAP7D1 other 0.226701098584382 1 1 3.18514370191538 -2.11142103640725 0.000655616802296602 62.3600716666288 23.5333877356545 2.64985527655883 0.00893393696267647 -144.07940267687 83.4979736366354 -1.72554370365766 0.0865309286194142 OSCP1 other 1 1 1 2.64985527655883 -1.72554370365766 0.00427466224672845 151.863681569378 118.784450567337 1.27848115510109 0.203094672572792 -1023.50906081794 421.454872257385 -2.42851400752789 0.0163682771916068 MRPS15 other 1 1 1 1.27848115510109 -2.42851400752789 5.33943563470842e-09 72.2591178162385 12.5612702968455 5.75253267453251 4.47020762224341e-08 -39.8130055846397 39.7889813558591 -1.00060379099846 0.318558082453139 EXOC8 other 5.78794822802392e-05 1 0.000528777281676317 5.75253267453251 -1.00060379099846 6.68111070902336e-13 282.468944088073 39.4486184186017 7.16042678835305 2.91958036874986e-11 -164.240030289571 124.957134563558 -1.31437097099913 0.190638361931243 GNPAT other 8.52576537578471e-09 1 3.85676566711857e-07 7.16042678835305 -1.31437097099913 3.12029638737191e-07 170.921141242258 37.46985596476 4.56156387158274 1.02163281725447e-05 -202.081309001263 117.279303550114 -1.72307732808895 0.0868560273205249 TSNAX other 0.00297239433861048 1 0.103675298294983 4.56156387158274 -1.72307732808895 1.18993334258151e-16 201.541486295011 24.2713190195756 8.30368906331221 5.13748879132779e-14 -187.289988762398 96.3064163566477 -1.94473012129135 0.0536534693881091 C1orf109 essential 1.63532539270976e-12 1 7.08356954548276e-10 8.30368906331221 -1.94473012129135 4.04270763077344e-11 225.074267307867 31.9790254405484 7.03818406618733 6.25261464941161e-11 -90.7107945437496 164.708366435743 -0.550735803570356 0.582623331193401 RRAGC other 4.86256873829429e-07 1 8.19655254391369e-07 7.03818406618733 -0.550735803570356 9.80431312406837e-11 94.9064079317928 17.0491826499273 5.56662509168422 1.09878477212397e-07 -139.484118411069 55.6175866380112 -2.50791389635272 0.0131607736062117 TBCE essential 1.16141893267714e-06 1 0.0012736014293689 5.56662509168422 -2.50791389635272 0.410097278296976 -143.816166592029 113.006649686594 -1.27263454841711 0.205017307257373 -297.867047759543 352.2025770259 -0.845726485804898 0.398984311193 NID1 other 1 1 1 -1.27263454841711 -0.845726485804898 0.0151510446637069 149.884225135214 94.5357154598363 1.58547723901124 0.11485734465071 -476.889910022914 289.272864508236 -1.6485815592611 0.101220392958479 LGALS8 other 1 1 1 1.58547723901124 -1.6485815592611 0.0791579980319243 5.9204533730305 2.93794382641105 2.01516901712271 0.0456852893108422 -13.5630138399634 21.4264604145977 -0.63300300551383 0.527702002953193 HPCAL4 other 1 1 1 2.01516901712271 -0.63300300551383 3.52885017637334e-06 238.269670456592 53.0516123365297 4.49128047127281 1.35984023588655e-05 -110.336398805273 162.334328277109 -0.679686175908067 0.497697777995344 MTR other 0.0304934012459312 1 0.136203196591486 4.49128047127281 -0.679686175908067 2.9352228454683e-05 38.4912228985807 8.96794411714754 4.2920899590556 3.17256143467185e-05 -72.9681813492121 65.4033266051635 -1.11566467849131 0.266361786662797 BMP8B other 0.230444345597716 1 0.306786690732768 4.2920899590556 -1.11566467849131 1.32523150704104e-13 608.675048709205 73.4155864216853 8.29081504863409 6.09949579610883e-14 -180.667888455919 527.093637842225 -0.342762415413556 0.732260278041161 MYCL other 1.72372862120828e-09 1 8.40266540871953e-10 8.29081504863409 -0.342762415413556 0.0435749693288655 27.9819411748696 35.666922136471 0.78453478738096 0.433908522197814 -232.661534379295 116.773834153435 -1.99241153693378 0.048059379168093 SIPA1L2 other 1 1 1 0.78453478738096 -1.99241153693378 5.25740687116068e-31 268.029953917051 18.084329311937 14.8211166305256 3.00620641824778e-31 -12.893817204301 133.312741301149 -0.0967185662709781 0.923078146119955 RLF other 7.62586866661856e-27 1 4.36681544314672e-27 14.8211166305256 -0.0967185662709781 3.96069892998351e-06 180.909333018777 42.7247480424639 4.23429841737093 3.9157594669192e-05 -101.067643452632 132.131559361333 -0.764901617305885 0.445493146906839 KMO other 0.0340778535935781 1 0.374189974658799 4.23429841737093 -0.764901617305885 7.99831005566436e-26 28.9002385149849 2.31195886297423 12.500325580104 5.0917041074964e-25 -26.2077058687449 16.1642993444592 -1.62133262384357 0.107046494360928 ZNF684 other 1.1539161917307e-21 1 7.3544574128678e-21 12.500325580104 -1.62133262384357 0.0261015402306926 47.3432650428772 18.756429394237 2.52410861618596 0.0126397764935557 -68.4928346776441 131.227532732201 -0.521939514152254 0.602482327892854 KCNQ4 other 1 1 1 2.52410861618596 -0.521939514152254 3.528512062709e-06 24.404737807578 5.05296781849082 4.82978294820548 3.3226625487223e-06 -34.9419650199253 35.3459523382944 -0.988570478608061 0.324454767391576 RIMS3 other 0.0304934012459312 1 0.0350839938519588 4.82978294820548 -0.988570478608061 0.489720495236005 53.5195057832071 44.9115877384726 1.19166363244292 0.235214587570633 88.833785084393 137.308958068042 0.646962778935167 0.518612967666469 AKT3 og 1 1 1 1.19166363244292 0.646962778935167 1.87397483362385e-05 187.129922228028 55.713784645605 3.35877240109176 0.000985381768949764 -369.863964372445 165.832480751031 -2.23034693021165 0.0271607295833907 ACADM other 0.150386480398314 1 1 3.35877240109176 -2.23034693021165 0.697156569356411 -45.2345100336895 135.509040837997 -0.333811749784046 0.738972797008874 -351.93970020995 415.184588485708 -0.847670433754708 0.397928570294299 ST6GALNAC5 other 1 1 1 -0.333811749784046 -0.847670433754708 2.15747109104537e-07 1149.16646808952 198.585758633338 5.78675165831654 3.88997964759142e-08 699.182440599529 593.016142448821 1.17902766982413 0.24020553392073 ADGRL2 other 0.00208800052191371 1 0.00046146828559377 5.78675165831654 1.17902766982413 0.61906280378637 -10.7457821632904 52.8745248466439 -0.203231749021996 0.839220452079001 -106.198674313811 117.201198299144 -0.906122768836796 0.366277296913587 PADI2 other 1 1 1 -0.203231749021996 -0.906122768836796 6.11549389125186e-07 206.261190336948 96.098992845848 2.146340811998 0.033401868615844 -654.463741058976 212.109529339602 -3.08549900184416 0.00240727274197087 SDHB ts 0.0056794591768056 1 1 2.146340811998 -3.08549900184416 4.75400380888682e-07 1635.56129471891 327.806722184061 4.98940742832161 1.6279572523621e-06 468.1939693356 720.918365687172 0.649441034685421 0.517027125365141 MFAP2 other 0.00445973097311672 1 0.0175526350949682 4.98940742832161 0.649441034685421 1.71293641257437e-06 93.365806551298 30.4846141585958 3.06271898556969 0.00258944272191162 -323.332895550062 97.180403733784 -3.32714089597528 0.00109735388626262 RPF1 essential 0.0152982351007017 1 1 3.06271898556969 -3.32714089597528 1.03846492590257e-14 969.354625550664 113.296392887518 8.55591780854884 1.78107379072304e-14 -248.409171320542 414.025553622752 -0.59998511963077 0.54947917712816 KDM5B other 1.38468913219848e-10 1 2.47123988462822e-10 8.55591780854884 -0.59998511963077 0.202940493745245 43.2539703077797 26.4284050867098 1.63664701543155 0.103733061054061 18.6358427516216 58.5809660565522 0.318121123738915 0.750821264412155 ACTL8 other 1 1 1 1.63664701543155 0.318121123738915 0.00860677618293938 8.41347342398027 33.9365142912511 0.247918019858312 0.80452809573916 -314.850046353523 108.18454657105 -2.91030518066409 0.00414642310276839 CTBS other 1 1 1 0.247918019858312 -2.91030518066409 1.9405603642668e-16 268.911567595629 31.425957615336 8.55698880801644 2.93652805638963e-14 -224.511468485264 108.839446783893 -2.06277664136831 0.0411402985252174 KLHL12 other 2.65953797922765e-12 1 4.06121830198686e-10 8.55698880801644 -2.06277664136831 0.892477496001707 -0.825734007662147 6.13929764728603 -0.134499751454008 0.893181897516195 4.1003378207328 13.6083121893569 0.301311269441606 0.763580990187044 IGSF21 other 1 1 1 -0.134499751454008 0.301311269441606 1.85291196944451e-08 206.280902348579 37.6046742315663 5.48551228175304 1.65632035039737e-07 -167.745519159456 119.878093424075 -1.39930085946602 0.163733770532937 SSX2IP other 0.000194481640312896 1 0.00190129013022114 5.48551228175304 -1.39930085946602 2.23077839548668e-11 123.390882756518 19.8014874271006 6.23139464703259 4.17164511158007e-09 -174.458250749606 65.002754216621 -2.68385936645432 0.00806874239661133 ZNHIT6 essential 2.70950343915812e-07 1 5.15448469986833e-05 6.23139464703259 -2.68385936645432 0.239066082355454 2.92594919993077 11.0052034246463 0.265869615220204 0.790692938252461 -28.5956394634024 24.2923850645747 -1.1771441703805 0.240942397269007 PLA2G2D other 1 1 1 0.265869615220204 -1.1771441703805 4.41128636097384e-14 136.4637838249 17.2499541966861 7.91096499555438 4.51616025363886e-13 -117.426631106547 63.3069793813564 -1.8548765436932 0.065513518597077 RBBP5 essential 5.81186978058303e-10 1 6.16455874621705e-09 7.91096499555438 -1.8548765436932 0.0894658633235939 -62.2750419271235 88.7296844765174 -0.701851272147876 0.483824452644262 -643.207653605733 291.274778876039 -2.20825042280599 0.0286951072110156 GBP3 other 1 1 1 -0.701851272147876 -2.20825042280599 0.268453669497021 207.349992376887 229.436982165748 0.903733959624236 0.36753890378645 -822.492300655588 753.177548647776 -1.09202976394113 0.276514498197432 GBP1 other 1 1 1 0.903733959624236 -1.09202976394113 8.61087908939266e-16 313.292372096694 54.3581980028931 5.76347972535844 4.31682579872611e-08 -286.758412793821 119.987811796866 -2.38989617778255 0.0180542592375617 PINK1-AS other 1.1697018155031e-11 1 0.000510982669795209 5.76347972535844 -2.38989617778255 3.66312447362697e-13 50.9105458563669 6.54645698690145 7.77680903704582 9.70533342707317e-13 33.7155451126108 14.4503511473798 2.33319901840061 0.0209227005111047 KIF17 other 4.71114438553165e-09 1 1.31837249273362e-08 7.77680903704582 2.33319901840061 0.445217413359717 46.9286574679848 55.7988910697313 0.841032080894557 0.401625554384364 -153.581354483059 206.164696233612 -0.744944975006927 0.45743302299159 CDK18 other 1 1 1 0.841032080894557 -0.744944975006927 0.013873087625767 71.3303257734803 25.3489925341671 2.8139313890813 0.00552874157550879 -24.7844816809 93.0236657285127 -0.266432004015332 0.790260624902627 RAB29 other 1 1 1 2.8139313890813 -0.266432004015332 2.41447936422546e-08 717.466451734158 175.202083590816 4.0950794478552 6.7961662102583e-05 -570.537828953855 415.613449087329 -1.37276074729231 0.171822504331092 ECE1 other 0.000251178288260375 1 0.632989275890243 4.0950794478552 -1.37276074729231 6.05695462469146e-10 159.697897283215 42.6125631427065 3.74767170771677 0.000253555267667281 -228.605361794885 93.9839520444712 -2.43238719826034 0.0161688814953662 HMGCL other 6.91461939954777e-06 1 1 3.74767170771677 -2.43238719826034 9.97963117362065e-06 86.1565872720507 64.9958901346875 1.32556977208117 0.186984229384858 -433.10956191185 143.351400877929 -3.02131377342217 0.00295685070366282 GALE other 0.0824716720188011 1 1 1.32556977208117 -3.02131377342217 0.63851157392227 -29.86488000747 109.158500668337 -0.273591885419995 0.784772138215021 -213.851164908021 241.15503611123 -0.88677876421948 0.376608196781752 ID3 other 1 1 1 -0.273591885419995 -0.88677876421948 0.772440652769529 4.62234842786219 6.52484856070037 0.708422331163811 0.479768035113356 2.37762900556641 23.091368483534 0.102966136773654 0.918125567696351 CR2 other 1 1 1 0.708422331163811 0.102966136773654 0.00554157816801336 486.927600052279 170.722210600919 2.85216316224093 0.00494701143654589 -378.566188429364 590.487676238303 -0.641107687193435 0.522418187646125 CD46 other 1 1 1 2.85216316224093 -0.641107687193435 0.0848950497897785 123.369063491172 86.8193930093249 1.42098509578294 0.157410521611995 -472.439771802285 386.3609059394 -1.22279393318429 0.223338118609119 P3H1 other 1 1 1 1.42098509578294 -1.22279393318429 0.0192387030803665 1222.42940016683 474.266376943851 2.57751647511702 0.010908418963847 -809.384507469473 2112.50576001192 -0.383139550570932 0.702155138709439 SLC2A1 other 1 1 1 2.57751647511702 -0.383139550570932 0.000183976214539028 370.847460447494 115.211694879004 3.218835213187 0.00157365724654816 -917.413784496441 529.598605802717 -1.73228134372807 0.0852519849611732 CDC20 essential 1 1 1 3.218835213187 -1.73228134372807 0.00349889605798695 29.8923237039746 9.43410367425444 3.16853881790067 0.00185700515646377 -15.213974290456 40.6125999395539 -0.374612172407082 0.708477999124607 ARTN other 1 1 1 3.16853881790067 -0.374612172407082 7.29210823026052e-14 330.393881403709 44.0440082168637 7.50144900021172 5.27449321874979e-12 -380.020559104192 187.146934540481 -2.03059996701143 0.0440741365048806 IPO13 essential 9.55047414917221e-10 1 7.07362285566535e-08 7.50144900021172 -2.03059996701143 0.00252077127567862 434.149693552976 208.888513129797 2.07837993122775 0.0393892466518153 -1919.91607618506 887.585995817535 -2.16307612471586 0.0321300605897174 ATP6V0B essential 1 1 1 2.07837993122775 -2.16307612471586 6.64588242248265e-07 211.631294219569 49.4106614681042 4.28310991861914 3.27695687975396e-05 -476.221501339622 209.948066556575 -2.26828238597422 0.0247392725890414 B4GALT2 other 0.00615475171146118 1 0.316029721483472 4.28310991861914 -2.26828238597422 6.51431268396817e-12 442.376573778748 73.6268105003766 6.00836258928376 1.34575448915552e-08 -969.622254948342 309.991055637424 -3.12790397437287 0.00211298077293243 ERI3 other 8.05820479006862e-08 1 0.000162863208277601 6.00836258928376 -3.12790397437287 0.11639790785654 24.2439149110247 13.8581690445718 1.74943131614641 0.0822616899567046 -28.0021988136634 47.6575434318391 -0.587571175457516 0.557703631751036 PTCH2 other 1 1 1 1.74943131614641 -0.587571175457516 2.58423458348161e-05 207.869053925589 88.2664157996778 2.35501863355765 0.0197744650158364 -927.526556411056 283.884004011358 -3.26727305274286 0.00133719875459037 AKR1A1 other 0.204412955553395 1 1 2.35501863355765 -3.26727305274286 0.000102106892717233 662.563286913739 323.637050910489 2.04724176372807 0.0423228578660699 -3275.74343437275 1040.88719391767 -3.14706862906399 0.00197812260338478 PRDX1 other 0.748341416724598 1 1 2.04724176372807 -3.14706862906399 0.0761559873796883 11.9007798609992 72.6425798977138 0.163826503377997 0.870079785782826 -516.005778244705 241.414414273477 -2.13742737689295 0.0341215799275769 PIK3R3 other 1 1 1 0.163826503377997 -2.13742737689295 0.123141594709624 -372.233473411993 239.678098441225 -1.55305585213191 0.122436186522478 -1390.24939389041 796.526607822064 -1.74538977133703 0.0828859995485792 TSPAN1 other 1 1 1 -1.55305585213191 -1.74538977133703 5.39447171063513e-05 55.3757862718655 19.8965627225127 2.78318356010349 0.00604835215173339 -179.365384678486 66.951706356161 -2.67902633764584 0.00817557333179835 FAAH other 0.409116734534568 1 1 2.78318356010349 -2.67902633764584 1.7732863663223e-13 172.782107946883 26.0570398214634 6.63091852070474 5.16347852185228e-10 -271.759542723642 87.6816414457086 -3.09938931619925 0.0023010990727848 NSUN4 essential 2.29888844530023e-09 1 6.57723894113543e-06 6.63091852070474 -3.09938931619925 0.00109241104148595 54.4506684035854 64.3562424346961 0.846082156813892 0.398811212482599 -703.841304550106 209.471196538601 -3.36008633253978 0.00098102675821696 TMED5 other 1 1 1 0.846082156813892 -3.36008633253978 1.36678403421131e-06 113.887588708406 50.6754358335953 2.24739238715938 0.0260264293851447 -694.79592072754 163.478072163777 -4.25008633593057 3.67662151885436e-05 DR1 essential 0.0123201912843807 0.530058524373233 1 2.24739238715938 -4.25008633593057 0.00662459124806966 239.859049652965 211.325335518825 1.13502268463971 0.258129306105278 -1731.68579818473 656.782961184726 -2.63661803141339 0.00923162734846312 CNN3 other 1 1 1 1.13502268463971 -2.63661803141339 0.330349253959152 -11.3028118882365 25.8569057998319 -0.437129329229715 0.662629911393374 -119.911787388029 80.361283310374 -1.49215869195246 0.137703279823044 F3 other 1 1 1 -0.437129329229715 -1.49215869195246 1.07856549001035e-06 129.055466571751 39.0438100552554 3.30540145516306 0.00117993639752308 -414.778736825453 121.345171988336 -3.41817255708635 0.000806762167935538 ABCD3 other 0.00981710309007418 1 1 3.30540145516306 -3.41817255708635 5.96126571039677e-05 104.724841211875 31.4250873961826 3.33252346736819 0.00107927341509365 -184.927239444172 96.624991599365 -1.91386551639698 0.0575044184177235 DPH5 other 0.449658272535228 1 1 3.33252346736819 -1.91386551639698 1.10226743086866e-05 267.223635041005 66.2911676130326 4.03105941052199 8.68254563001386e-05 -370.48953174358 204.263190102205 -1.81378510517829 0.0716450028442742 PTBP2 other 0.090694564211873 1 0.799228325242776 4.03105941052199 -1.81378510517829 0.494101808453893 -6.01463986599666 7.03045774175477 -0.855511843883928 0.393632316238876 11.4749748743718 23.9641988735436 0.478838242618666 0.632750976033707 HSD11B1 other 1 1 1 -0.855511843883928 0.478838242618666 3.8708058975057e-08 305.800435600333 59.9408843642854 5.10170043107569 9.96769737491985e-07 -303.114133892348 199.621497728857 -1.51844434262318 0.130993374481821 IRF6 other 0.00039702856090716 1 0.0108926996913124 5.10170043107569 -1.51844434262318 3.79543624566481e-13 219.959788759855 33.019337910888 6.66154449715128 4.52758179090895e-10 -226.90829897448 102.484253570595 -2.21407963729938 0.0282927243748675 DIEXF essential 4.87865375017755e-09 1 5.77493057430437e-06 6.66154449715128 -2.21407963729938 0.581569254833578 -8.55909967845653 10.3339915954632 -0.828247207227666 0.408820624540619 -27.5712094978976 32.5997502808711 -0.845749101154184 0.399013467545326 PLPPR4 other 1 1 1 -0.828247207227666 -0.845749101154184 1.43150527964185e-14 304.58498349835 44.3645351023683 6.86550603529463 1.50318875526105e-10 -29.1241749174913 98.3859685579204 -0.296019598570559 0.767611340846393 RCAN3 other 1.90390202192367e-10 1 1.94843326456937e-06 6.86550603529463 -0.296019598570559 8.09592498332791e-13 169.81693841973 43.6518544353946 3.89025714064592 0.000148634774130123 -323.765773214377 96.1094039717609 -3.36872105990281 0.000954226949278412 SYF2 essential 1.03069220962748e-08 1 1 3.89025714064592 -3.36872105990281 3.77231231638316e-06 111.499431002249 98.1893170268166 1.13555562232699 0.257941763671014 -744.102555070854 216.879721807001 -3.43094572821808 0.000775965247395313 RSRP1 other 0.0325060152302737 1 1 1.13555562232699 -3.43094572821808 8.82487956306406e-05 86.681055444098 40.0071084563414 2.16664134921649 0.0318099244078043 -372.303135083162 123.012753147616 -3.0265409525173 0.00290317435808895 SLC35A3 other 0.651959809422869 1 1 2.16664134921649 -3.0265409525173 3.66184170302941e-12 228.345708888056 37.3273130881687 6.11738938585518 7.44266395214776e-09 -268.201036265585 111.524470281551 -2.40486267801581 0.017357607046932 RCOR3 other 4.56814752452919e-08 1 9.11130921021929e-05 6.11738938585518 -2.40486267801581 2.57262141846961e-11 154.618948678256 47.633879461351 3.2459868989615 0.00143434371808877 -369.525454581461 101.538023077853 -3.63928155562113 0.000371933244293587 MTFR1L other 3.11724537275962e-07 1 1 3.2459868989615 -3.63928155562113 0.016751661788967 71.0794695213416 30.9130337279002 2.2993365887991 0.0228296759325702 -3.46801445520248 65.7489609033452 -0.0527463005886992 0.958002407119028 MAN1C1 other 1 1 1 2.2993365887991 -0.0527463005886992 0.0100392538754082 40.8672874458431 35.4119870144409 1.15405236732911 0.250243631149257 -235.914949112668 106.24653125986 -2.22044848255481 0.0278296433138239 NEK2 other 1 1 1 1.15405236732911 -2.22044848255481 1.13427703401539e-07 54.7853889180122 51.2267682680368 1.06946799047239 0.286532261099061 -447.535989060858 108.278123033417 -4.13320785882796 5.85639639569887e-05 RPS6KA1 other 0.00112350140219224 0.842208365665454 1 1.06946799047239 -4.13320785882796 1.38378571405912e-13 137.176398735755 31.7620950216398 4.31887124077602 2.79826617643528e-05 -229.079149298575 67.1356040763174 -3.4121857165114 0.000823404938905491 DHDDS essential 1.79892142827686e-09 1 0.271879541702451 4.31887124077602 -3.4121857165114 0.0865248039119362 37.095930915067 81.0823592125578 0.457509269282851 0.647941580521645 -450.961554264249 242.382275428156 -1.86053849633868 0.0646917902936852 NENF other 1 1 1 0.457509269282851 -1.86053849633868 2.70592425567734e-05 59.0497461000689 30.804861760084 1.91689696775668 0.0570673601707225 -299.400803195904 91.228060458324 -3.28189376921676 0.00127077658190978 NSL1 essential 0.213686838470839 1 1 1.91689696775668 -3.28189376921676 0.197386605935233 -2.90449027505395 2.81031342551944 -1.03351115526095 0.302964292275801 -14.7906939963307 8.36239490934373 -1.76871508182475 0.0788957557361187 PROX1 other 1 1 1 -1.03351115526095 -1.76871508182475 2.54991129555808e-15 1682.79577666242 246.565603522664 6.82494132442013 1.89989792983829e-10 -457.02632997859 520.125501707944 -0.878684718357099 0.380941170274227 ARID1A other 3.43779040867140e-11 1 2.45523809473002e-06 6.82494132442013 -0.878684718357099 0.000105609409942089 409.193271338826 117.885165103062 3.4711175997513 0.000670564846487714 -428.489742076928 358.967814989452 -1.1936717560306 0.234418453908397 CENPF other 0.772321614906495 1 1 3.4711175997513 -1.1936717560306 1.54530023306896e-10 225.443898916967 57.213850454424 3.94037277908001 0.000124014130717313 -319.211205776174 120.526890439814 -2.64846462570586 0.00894516189611766 RPA2 essential 1.81464606369288e-06 1 1 3.94037277908001 -2.64846462570586 1.40128966396956e-12 152.7157132574 38.3501921255809 3.98213684972738 0.00010528224486283 -272.753757886267 80.8625134727015 -3.3730556493071 0.000941736809800314 PPP1R8 essential 1.77179065112311e-08 1 0.960740174246502 3.98213684972738 -3.3730556493071 5.76125247029973e-07 24.1794046661306 32.2260911583364 0.750305227752569 0.454223179327925 -276.626575489406 67.9496655956848 -4.07105131518078 7.48194925389669e-05 STX12 other 0.00536603055083717 1 1 0.750305227752569 -4.07105131518078 0.515342539234402 -3.19546706517668 10.4775170310538 -0.304983237508064 0.760788060397574 -36.924694905348 32.1876314694255 -1.14717030174843 0.253078902540067 MARC2 other 1 1 1 -0.304983237508064 -1.14717030174843 6.22430907389171e-17 518.408437061075 69.4276228159778 7.46689020932128 5.82027989518648e-12 -774.201691932645 215.79061337447 -3.58774498957999 0.000448376107080106 OSBPL9 other 8.58394464380405e-13 1 7.79859303156036e-08 7.46689020932128 -3.58774498957999 3.64972831208365e-07 259.274996298673 106.754494652388 2.42870332666478 0.0163276786304863 -1361.51944019477 331.402310173508 -4.10835832581234 6.51157149131951e-05 TXNDC12 other 0.00345665768437443 0.935712823302614 1 2.42870332666478 -4.10835832581234 0.000447503810958546 510.239334639574 158.403725310609 3.22113216491002 0.0015679870634465 -490.671662495472 445.392937799333 -1.10166017656198 0.272385830412167 ESYT2 other 1 1 1 3.22113216491002 -1.10166017656198 4.61164486760293e-15 86.8099701551406 16.0170174966478 5.41985860809038 2.2063299806949e-07 -237.723757855387 51.3769076521318 -4.62705461887649 7.7151831317048e-06 CD3EAP other 6.18974974129666e-11 0.112117041269934 0.00251256858201536 5.41985860809038 -4.62705461887649 6.23095369599039e-07 1726.53235051951 319.253644541319 5.40802706575227 2.42311491088708e-07 582.512993530678 557.855820542127 1.04419990269993 0.298050732490861 RCN2 other 0.00578294812524868 1 0.00275265853876772 5.40802706575227 1.04419990269993 0.497943536879052 -6.0713739485088 6.88126342232341 -0.882305119843653 0.379005006905575 -13.1218455263829 12.2850745631232 -1.06811281111565 0.287163041118772 CHRNB4 other 1 1 1 -0.882305119843653 -1.06811281111565 0.90174536732738 198.990874796084 579.204646142636 0.343558837314783 0.731655978347157 -72.8185494834148 1031.50984665779 -0.0705941389889344 0.94381418332432 MUC5B other 1 1 1 0.343558837314783 -0.0705941389889344 0.123578172218238 85.0663450390749 1794.75585187766 0.0473971682276891 0.962258903739543 -5163.07202961968 3102.63909454596 -1.66409043149611 0.0981545851343752 CTSD other 1 1 1 0.0473971682276891 -1.66409043149611 0.782338817678828 -24.2354356500778 44.7056354012826 -0.542111423594318 0.588535606071827 -80.0147800295465 130.610657431976 -0.612620605414374 0.541042679969228 COLEC11 other 1 1 1 -0.542111423594318 -0.612620605414374 8.93860109385957e-08 247.650804265953 43.6803397789326 5.66961716688379 6.87087959588836e-08 -154.258737812819 171.649707514509 -0.898683371189431 0.370224305030286 STAG1 other 0.000893323793320326 1 0.000805060962250239 5.66961716688379 -0.898683371189431 1.51409105790694e-06 261.201235370611 60.8408040394724 4.29319170734741 3.28337971488664e-05 -92.6178813202783 91.2860559455939 -1.01458958173719 0.312064302764886 STK11 ts 0.0135919954268306 1 0.316550638312221 4.29319170734741 -1.01458958173719 2.15699378072432e-11 661.939151860366 102.360348731031 6.46675358248067 1.25687372008401e-09 -406.107184429305 289.676252328198 -1.40193468109768 0.162947125228888 KMT2A og 2.62096314295812e-07 1 1.58064439037765e-05 6.46675358248067 -1.40193468109768 5.85874031049049e-08 92.4529593153144 16.8162314144801 5.49784057061116 1.58821699176589e-07 -23.4213775526257 47.7091234521132 -0.490920307436257 0.624190834461188 TREH other 0.000593256043840267 1 0.00182533778863654 5.49784057061116 -0.490920307436257 2.34333560781767e-08 140.039026607819 29.0092273538699 4.82739594886651 3.30484769013869e-06 -164.206549292807 81.2589323241576 -2.02078152636506 0.04503523226907 IFT46 other 0.000243988103485976 1 0.0349058013032448 4.82739594886651 -2.02078152636506 0.0548630064948509 1068.94462812987 697.954848471302 1.5315383659432 0.127728763732003 -1871.49074968422 1867.93039914928 -1.00190604025533 0.317991817213121 APOA1 other 1 1 1 1.5315383659432 -1.00190604025533 0.0265172801473542 15.0043564803277 7.64311331989933 1.96312102834625 0.0513990199005019 -5.7484338899479 14.7223095700458 -0.390457343842553 0.696727663874307 ZNF541 other 1 1 1 1.96312102834625 -0.390457343842553 0.00671872302570443 6.93329381571768 2.72482667527811 2.54448984906903 0.0119088696649413 -0.57906329778995 5.24861272614123 -0.110326924085267 0.912291008709813 SLC8A2 other 1 1 1 2.54448984906903 -0.110326924085267 2.13191793029302e-09 39.5039085391731 9.776524528966 4.04069037234351 8.32133328297136e-05 -38.1645207029643 18.8317266289701 -2.02660762100557 0.0443950756427902 KPTN other 2.36621571083222e-05 1 0.767476568688449 4.04069037234351 -2.02660762100557 0.00517218122958671 1507.48837785515 706.624459594943 2.13336569005733 0.034543642517682 -3064.22083066291 1950.30167779679 -1.57115223021522 0.118282741933214 RPS25 essential 1 1 1 2.13336569005733 -1.57115223021522 0.000235546900168753 57.4068443461368 15.3718411150828 3.73454577863217 0.000263721904560823 -59.3545089365018 54.4443664134856 -1.09018642049621 0.277322951012111 KIF14 other 1 1 1 3.73454577863217 -1.09018642049621 0.367192675817916 29.80168079885 31.8602001769314 0.935389000488079 0.351052314225473 -103.425499019848 125.774046437061 -0.82231193119483 0.412170776261975 TNNT2 other 1 1 1 0.935389000488079 -0.82231193119483 0.0134693428291864 41.441215726761 14.4359247513983 2.87070045323886 0.00466852597151181 -8.6689548765394 51.2215895995699 -0.169244159431792 0.865825268342778 DDX59 essential 1 1 1 2.87070045323886 -0.169244159431792 6.28326282375815e-08 236.27080125922 41.2670291031641 5.72541339645661 5.24445252807058e-08 -119.684609021348 146.456129107452 -0.817204508617988 0.415074029588834 CAMSAP2 other 0.000635049373597236 1 0.000618373397584802 5.72541339645661 -0.817204508617988 0.616431694675451 -7.78799052993449 11.6787467647322 -0.666851562656781 0.505858410945422 -31.0599273529221 33.4951508474773 -0.927296237427195 0.35521441898521 CRYGD other 1 1 1 -0.666851562656781 -0.927296237427195 0.000585897233162378 89.0314159292037 28.932307697071 3.07723175286903 0.00247363467467503 -72.9199641803621 77.2603806230929 -0.943820928557094 0.346739528838651 MREG other 1 1 1 3.07723175286903 -0.943820928557094 2.30593433909425e-11 175.933343605547 28.4461017119051 6.18479626443565 5.22669628257360e-09 -120.996271186441 80.4215405033301 -1.50452565853834 0.134468006325874 FASTKD2 other 2.79848191392479e-07 1 6.43510846310461e-05 6.18479626443565 -1.50452565853834 0.736176581453924 141.359331476323 272.780869937384 0.518215707387295 0.605046714918965 -254.580779944289 781.677569300229 -0.325685154522464 0.745101828551112 NRP2 other 1 1 1 0.518215707387295 -0.325685154522464 4.25936885879475e-11 249.36426503699 36.5306350570512 6.82616835561574 1.82587443620775e-10 -15.707944676745 104.81862569629 -0.149858334550755 0.881069959374026 CREB1 other 5.11677981007013e-07 1 2.36085564601663e-06 6.82616835561574 -0.149858334550755 0.482313163786199 37.8788597842836 47.3024399050064 0.800780252780884 0.424476768077255 -67.4738983050847 133.731332512768 -0.504548164123337 0.614588157751826 KLF7 other 1 1 1 0.800780252780884 -0.504548164123337 4.60754940608078e-26 89.1443091582848 6.97190094541955 12.7862271504089 8.75530285569173e-26 54.8175318406876 28.2017942300084 1.94376043572286 0.0537961091086519 B4GALT6 other 6.6500760577964e-22 1 1.26592923990447e-21 12.7862271504089 1.94376043572286 3.64511538487929e-27 44.2692000676916 3.24003944917227 13.6631669960071 1.01729926444444e-27 -57.3934111352659 58.9972970262563 -0.972814247909076 0.332288303101805 CASC1 other 5.26974331192e-23 1 1.47416836410644e-23 13.6631669960071 -0.972814247909076 0.00093699956168192 4.84971374269386 1.31055925388585 3.70049177731897 0.000306252885214365 -14.5979106731407 23.8637383232371 -0.611719357437229 0.541694773258794 LRMP other 1 1 1 3.70049177731897 -0.611719357437229 0.486070858122927 -20.7375621890548 37.0010767409805 -0.56045834379968 0.575981291088494 -72.7748756218905 60.4580096635328 -1.20372595834538 0.230542533891649 ATP10B other 1 1 1 -0.56045834379968 -1.20372595834538 0.00120931986754657 204.836716898872 55.64836746456 3.68091152052795 0.000320301799294707 55.9972324898116 231.92663389632 0.24144373394754 0.809530332953802 SPCS2 essential 1 1 1 3.68091152052795 0.24144373394754 0.0351745361332663 41.8580855096042 16.2277594637379 2.57941249395144 0.0108709980486554 10.4812279640105 60.062435905511 0.174505542540754 0.86170666235502 USP35 other 1 1 1 2.57941249395144 0.174505542540754 0.176807836368167 15.2434861907243 8.59423783266986 1.77368679893617 0.0781440388589448 7.81136008337679 16.5634593243641 0.471601972172966 0.637896163849639 ELOVL4 other 1 1 1 1.77368679893617 0.471601972172966 2.16011101383348e-09 356.612668559261 52.7961646151512 6.75451846092854 2.95537044066537e-10 349.6160397445 101.886173775474 3.43143752276876 0.00077591673183494 FILIP1 other 2.39534710323995e-05 1 3.79144473832961e-06 6.75451846092854 3.43143752276876 2.78987350977773e-09 150.762737738979 25.0620421451534 6.01558072825022 1.37664150668609e-08 51.3184714896931 49.9111652599392 1.02819622067376 0.305557944554087 CASP8AP2 other 3.07527756982799e-05 1 0.000166504790233683 6.01558072825022 1.02819622067376 0.0010497273870725 365.266053380136 136.98504970477 2.66646655359366 0.00850062530895708 -205.834775767112 264.216065627439 -0.779039591246325 0.437175581140647 HMGN3 other 1 1 1 2.66646655359366 -0.779039591246325 9.19221781989216e-13 27.3308581150833 5.45622715721344 5.00911295068615 1.4823364337528e-06 -27.7208562058705 10.5326687455684 -2.63189291104725 0.00935527681880802 UBE3D other 1.16851472926469e-08 1 0.0160240568488678 5.00911295068615 -2.63189291104725 0.0452351537638687 12.2798170767588 5.41066582641253 2.26955747605296 0.0246408720117554 4.98372184907152 10.7419504104324 0.463949437360223 0.643347716317321 CNR1 other 1 1 1 2.26955747605296 0.463949437360223 7.61880530936693e-10 64.3093711467324 15.0660419352853 4.2684980848299 3.40419815761738e-05 -179.419317714755 45.4647153451063 -3.94634204465701 0.000119708303488359 ANKRD13C other 8.65343907037896e-06 1 0.327517904744368 4.2684980848299 -3.94634204465701 0.271499831511426 -8.77496252263808 5.44408537428247 -1.61183411341976 0.109006514691415 -4.50948415552457 16.8199323966107 -0.268103583842778 0.788971514470509 SGIP1 other 1 1 1 -1.61183411341976 -0.268103583842778 9.22240873616266e-14 507.855993532007 69.2489689537373 7.33376974711763 1.81766156055856e-11 21.7285371838703 135.82554316879 0.159973865570104 0.873139015740053 PHF3 other 1.20463102911757e-09 1 2.41130982623699e-07 7.33376974711763 0.159973865570104 0.000351632122601651 260.004306927354 88.2229290648525 2.94712848103496 0.00370665455595492 -117.904795580433 180.871916513284 -0.651869001298349 0.515457381217911 PLAGL1 other 1 1 1 2.94712848103496 -0.651869001298349 8.76911325124939e-17 141.213386861389 18.2430528830282 7.74066642062757 1.16241877107913e-12 -16.2490872358437 37.5109550898389 -0.43318244488649 0.665480584150991 FBXO30 other 1.20741920356453e-12 1 1.57647233733751e-08 7.74066642062757 -0.43318244488649 0.234344299497802 43.7105316551581 192.791764930568 0.226724059873097 0.820937052658364 -489.266016948578 392.972237059519 -1.24503965117127 0.214996214765998 TNFAIP3 ts 1 1 1 0.226724059873097 -1.24503965117127 2.91224095828455e-10 56.5431551802698 10.3033470140771 5.48784342631737 1.59975026870933e-07 -4.79138350573428 21.3426473863026 -0.224498086812291 0.822661660676141 AKAP7 other 3.37761706341843e-06 1 0.00183763313366641 5.48784342631737 -0.224498086812291 0.00659710382280778 71.6573602420924 48.7142139862512 1.47097437027962 0.14332526950452 -153.215517767463 99.3098108029242 -1.54280344035206 0.124917638492844 RAB32 other 1 1 1 1.47097437027962 -1.54280344035206 0.0541777273762113 68.6676808186974 33.4908138715776 2.05034374745288 0.0420375535121582 2.54303231457179 66.8732275429791 0.0380276593190809 0.969715201842682 MYB other 1 1 1 2.05034374745288 0.0380276593190809 0.0310262998043352 -48.2939022583081 122.436282905578 -0.394441101217945 0.693804669094091 -591.480077402102 246.487813100835 -2.39963213580922 0.0176140203030975 SGK1 other 1 1 1 -0.394441101217945 -2.39963213580922 1.21697147021918e-14 184.22289679098 28.0563574955019 6.56617299022209 7.94398802152797e-10 -31.2662619254119 54.3218143013374 -0.575574699180144 0.565765148231622 RNF146 other 1.62039751259683e-10 1 1.00586776328587e-05 6.56617299022209 -0.575574699180144 0.11116380374784 -173.167755465517 624.105242467081 -0.27746563188764 0.781787609153527 -2307.79546103437 1255.2954009864 -1.83844811286724 0.0678859755678421 CTGF other 1 1 1 -0.27746563188764 -1.83844811286724 0.734126398047638 -29.4137803170888 38.0064596109006 -0.773915292774406 0.440167329832501 -42.579536698582 76.5989648321534 -0.555876137384936 0.57910223918381 TCF21 other 1 1 1 -0.773915292774406 -0.555876137384936 1.26862014033411e-17 62.8940875896402 8.34587578880312 7.53594819539722 3.78085960962087e-12 5.63323391594846 13.2218643639225 0.426054432332511 0.67065923899276 PMFBP1 other 1.76224023693811e-13 1 5.08223148725237e-08 7.53594819539722 0.426054432332511 3.07343399897034e-09 291.153002619463 118.43093597666 2.45842017728241 0.0151084865992912 -792.218902893958 223.117349476675 -3.55068265534759 0.000515563888594473 FBXL5 other 3.38077739886737e-05 1 1 2.45842017728241 -3.55068265534759 1.13571908750251e-18 671.295859712517 88.7435381178081 7.56444777783555 3.6286658810978e-12 -184.581670442928 162.696486549315 -1.13451540569672 0.25838817246025 MED28 essential 1.59148315731727e-14 1 4.87946701031221e-08 7.56444777783555 -1.13451540569672 0.726214232910574 -3.18085587030307 4.87110129614731 -0.653005486217027 0.514759056525202 4.50186859066432 15.5403202582954 0.289689563396303 0.77245646708103 SLC16A7 other 1 1 1 -0.653005486217027 0.289689563396303 7.3996118988998e-14 67.8269689271056 11.9222797181363 5.68909390910587 6.36996504038988e-08 -142.95936837991 33.4764933377776 -4.27044036355455 3.42340440812908e-05 TMEM5 other 9.68683193684973e-10 0.493860319916702 0.000748216093644195 5.68909390910587 -4.27044036355455 4.90197615760268e-09 41.6919964755941 8.48018154333448 4.91640376595056 2.23694871954767e-06 -48.955451397215 27.7801359979465 -1.76224664273903 0.0800116091047361 ZNF430 other 5.32550689761955e-05 1 0.0239085079145255 4.91640376595056 -1.76224664273903 3.40661355357677e-09 64.9986924686193 16.7662844528117 3.87674995325031 0.000156723317385195 -204.120252655294 53.2217572397446 -3.83527833806402 0.000182898488601702 DCLRE1B essential 3.73875837505051e-05 1 1 3.87674995325031 -3.83527833806402 1.04770420195163e-05 868.763645942312 406.979883732954 2.13465991973295 0.0344247196518829 -2998.4936631636 1069.85230144257 -2.8027174023185 0.0057417122055588 MYL12B other 0.086444113063495 1 1 2.13465991973295 -2.8027174023185 2.0618370932659e-19 640.698621263997 85.3414090203875 7.50747648320334 4.86381039297616e-12 -247.474414731192 178.030348913402 -1.39006869470086 0.166553763820069 FOXO3 other 2.90347899473703e-15 1 6.5282063094526e-08 7.50747648320334 -1.39006869470086 1.01981462720136e-11 43.8406191754022 6.59695850340817 6.64558055848812 5.16182047591812e-10 13.6817505849383 13.7618869621478 0.994176933916845 0.321727202367183 ARMC2 other 1.25325019536775e-07 1 6.5756431042721e-06 6.64558055848812 0.994176933916845 4.83666181142608e-06 1212.02544031311 269.736052290113 4.49337576502204 1.40394613416639e-05 -1260.5748983359 1333.75260120955 -0.945133975515938 0.346130929101409 RPN2 essential 0.0411648286770474 1 0.140394613416639 4.49337576502204 -0.945133975515938 0.5172249135233 0.617969975352878 1.9726557336387 0.313268029902506 0.754503680656862 -6.45628156293629 6.67856178815879 -0.966717351388946 0.3352109430181 CASQ2 other 1 1 1 0.313268029902506 -0.966717351388946 0.236819873760705 34.0765632401706 24.2466645721213 1.40541240791328 0.161939303641462 -34.4974932891204 72.5103483327658 -0.475759585801518 0.63492871363231 OLFM3 other 1 1 1 1.40541240791328 -0.475759585801518 0.000989463887562658 10.6705752212388 39.9914186832355 0.266821622552539 0.789958888336731 -163.833824975418 60.2970313891361 -2.71711262065443 0.00732971940592303 PKD2 other 1 1 1 0.266821622552539 -2.71711262065443 0.707993556213692 -5.91736111111109 7.82510323612649 -0.756202305905966 0.45066833512063 -8.89675925925922 11.7051301165967 -0.760073503723339 0.448357815226228 ABCG2 other 1 1 1 -0.756202305905966 -0.760073503723339 0.618660300253154 -1213.38407079646 1710.34820991131 -0.709436864239112 0.479112402805861 -2517.70378564406 2578.77622487564 -0.976317278466249 0.330418809747693 SPP1 other 1 1 1 -0.709436864239112 -0.976317278466249 1.17564084251217e-33 135.083860056371 8.8345928487813 15.2903322618886 1.49391151210356e-32 6.39146300648268 34.3756436962711 0.185929987608523 0.852747561751293 STBD1 other 1.70867640050719e-29 1 2.17140038284252e-28 15.2903322618886 0.185929987608523 1.51459700223629e-09 1662.12371648274 533.946228317911 3.11290468652419 0.00221145335274482 -2597.12993517822 867.562122683338 -2.99359534870586 0.00321597499399799 CCNI other 1.69392528730107e-05 1 1 3.11290468652419 -2.99359534870586 0.483023024629049 10.6283452552745 231.288605928957 0.0459527403547892 0.963408235514702 1139.37356955638 942.361843696036 1.20906165415999 0.228516490155525 RARRES1 other 1 1 1 0.0459527403547892 1.20906165415999 0.467182385895857 55.6013905989175 45.5969177468436 1.21941116519365 0.224577020396246 -34.156818164651 185.779992499805 -0.183856279166804 0.854371247985256 MFSD1 other 1 1 1 1.21941116519365 -0.183856279166804 5.1045632224846e-13 175.550048730444 28.4933633255407 6.16108553857822 5.9658220622485e-09 -236.926138326067 86.3337280038669 -2.74430565902882 0.00677988350063555 RAB3GAP2 other 6.53843503168052e-09 1 7.3319953145034e-05 6.16108553857822 -2.74430565902882 4.42994608958279e-24 259.876644757125 21.2280483765446 12.2421355061668 1.69938423573748e-24 45.6050054876619 67.5767476067608 0.674862391322001 0.500775122421114 EEF2KMT other 6.36361755768568e-20 1 2.45323108271062e-20 12.2421355061668 0.674862391322001 1.80305404763008e-09 812.358021578764 123.108568502649 6.59871227047273 6.30443423555776e-10 27.4406189454968 391.67574323751 0.0700595311792311 0.94423716997685 PPL other 2.00842190365515e-05 1 8.00915325285257e-06 6.59871227047273 0.0700595311792311 8.27863371397582e-29 664.905889094595 46.8851487992089 14.181588544 9.75617062364796e-30 337.216631402628 148.008597863324 2.27835839451722 0.0240802142907414 UBN1 other 1.19841501643514e-24 1 1.41532767237261e-25 14.181588544 2.27835839451722 1.64661615832272e-10 259.511227601123 39.385607206161 6.58898633307165 7.51782867151106e-10 24.0270406553957 74.013641862941 0.324629893228186 0.745925863197963 KLF12 other 1.93016346078589e-06 1 9.52508892680452e-06 6.58898633307165 0.324629893228186 0.000916495659843703 50.7024929163396 27.761380402038 1.82636786002966 0.0698237392094396 -110.523851648863 50.6836084266046 -2.18066264577262 0.0307987382628574 UCHL3 other 1 1 1 1.82636786002966 -2.18066264577262 0.0270797731918869 207.608766819922 87.1375539398016 2.38254067773519 0.0185274407514852 16.6536480273452 156.234727253166 0.106593766444507 0.915262773842289 PCDH17 other 1 1 1 2.38254067773519 0.106593766444507 0.00194135418871315 72.3823825959851 28.4476661643936 2.54440494969609 0.0119643734266298 -174.689246789828 96.980203065881 -1.80128769859512 0.0736796827318993 HS1BP3 other 1 1 1 2.54440494969609 -1.80128769859512 0.0019574529129053 80.5080453587917 24.9181669728301 3.23089757952802 0.00151679381415481 -59.9082831734279 85.0433488322291 -0.704444074652012 0.482248526230189 LDAH other 1 1 1 3.23089757952802 -0.704444074652012 3.54406297631802e-15 233.664487077303 27.54755612929 8.48222201565307 2.01948017269128e-14 -97.144010275207 91.7274852011642 -1.05905018612648 0.291290746988498 WDR35 other 4.76428385906431e-11 1 2.80000925943646e-10 8.48222201565307 -1.05905018612648 0.000679633393650096 804.591202117839 219.320796122796 3.66855864259837 0.000334869063897406 -4.55671857000003 1005.46995699863 -0.00453192911263309 0.996389883614056 CCND2 og 1 1 1 3.66855864259837 -0.00453192911263309 0.161240472832001 -33.5361158964205 36.9928896887438 -0.906555724048366 0.366039925008217 -100.480487242441 53.825463091991 -1.86678351602315 0.0638085710726855 ELL2 other 1 1 1 -0.906555724048366 -1.86678351602315 0.0409437134396464 15.7992743764172 12.747616164738 1.23939050032905 0.217086376269098 -75.6965986394557 43.9963888032846 -1.72051844931883 0.0873468192240353 DNAH7 other 1 1 1 1.23939050032905 -1.72051844931883 2.29944469990903e-06 45.0526396444717 10.687112592642 4.21560447257665 4.21820445677289e-05 -46.2861849666692 31.638421025764 -1.46297392429847 0.145499329767819 CYP20A1 other 0.0202788028084978 1 0.401826156552186 4.21560447257665 -1.46297392429847 0.249790460091402 12.4904375093325 57.6009224340675 0.216844400775519 0.828618484494191 -252.355123189488 170.78465022629 -1.47762180532687 0.141564577602218 NDUFB3 other 1 1 1 0.216844400775519 -1.47762180532687 8.35308703642016e-07 198.118304032026 42.0151495108685 4.7154016191416 5.38954088532607e-06 -184.510018158557 145.811406896246 -1.26540180968041 0.207651015606752 GTF3C3 other 0.00766980451684099 1 0.0560242775029645 4.7154016191416 -1.26540180968041 0.194771554383861 15.3031657355679 9.45688355287212 1.61820388820588 0.107664988851601 -6.96269397889503 28.5051422358207 -0.244260980046801 0.807353829665908 SATB2 other 1 1 1 1.61820388820588 -0.244260980046801 2.52637883258294e-06 233.960603302562 72.1544819242025 3.24249578215162 0.00144730354715098 -238.092699258873 119.433287092215 -1.99352044187681 0.0479366473889763 UBE2B other 0.0221689742559153 1 1 3.24249578215162 -1.99352044187681 0.155857546914829 19.1644692971592 26.0091414475778 0.736835905782811 0.462335965686443 -69.1239799061356 47.8041251519822 -1.44598357749194 0.150200801585671 GDA other 1 1 1 0.736835905782811 -1.44598357749194 0.743768199154583 21.2568397543272 41.8438517222789 0.50800389733265 0.612177468374172 54.982691233947 77.3437933695379 0.71088692238364 0.478229586476555 KLF9 other 1 1 1 0.50800389733265 0.71088692238364 0.0116270055982751 146.091774087776 85.631629112321 1.70604922038971 0.0900148134878757 -275.628121594989 156.508370240259 -1.76110786389167 0.0802048614240263 TJP2 other 1 1 1 1.70604922038971 -1.76110786389167 0.0267765180158114 103.904120231961 43.0408192074742 2.41408323877622 0.0169403596131278 -45.6218386589513 117.860748704594 -0.387082545804097 0.69922604757573 C2orf40 other 1 1 1 2.41408323877622 -0.387082545804097 1.41778594567759e-06 362.772587342254 85.8401990394986 4.22613870193063 4.08479643773088e-05 -496.482807909335 266.564054015681 -1.86252722537049 0.0644589781549057 ITGB1BP1 other 0.0127600735110983 1 0.389526188302016 4.22613870193063 -1.86252722537049 2.03589927353472e-16 433.773670617232 50.6612013697256 8.56224603620334 1.10088439695632e-14 -217.890478874963 159.539415519338 -1.36574700468645 0.174022738249577 CPSF3 essential 2.78979277452463e-12 1 1.53044948864867e-10 8.56224603620334 -1.36574700468645 5.22044516239909e-07 72.9765181731363 13.043544969821 5.59483777929872 1.06803160407671e-07 19.5867835140347 48.8098113164204 0.401287835084202 0.688798983376021 PIGZ other 0.00488007213781067 1 0.00123880985756858 5.59483777929872 0.401287835084202 6.19430302055917e-14 235.852227402955 27.4825414076795 8.58189291537099 1.31420989326302e-14 54.531580622811 102.841494678648 0.530248814383802 0.596750509256834 SENP5 other 8.13002271448391e-10 1 1.82556896273166e-10 8.58189291537099 0.530248814383802 1.90975419378419e-10 231.432318758281 54.0278462486232 4.28357476426666 3.25930859330678e-05 -375.089710391824 122.941200492486 -3.05096834006227 0.00269528031231418 CCDC92 other 2.23345752963062e-06 1 0.314458093082238 4.28357476426666 -3.05096834006227 1.59084668336077e-08 610.953478695074 107.718346629224 5.6717680674958 6.56460534301287e-08 -258.912211254559 340.356173411939 -0.760709607994073 0.447964291490331 C1orf198 other 0.000167595698092057 1 0.00077055337516285 5.6717680674958 -0.760709607994073 2.84667069431645e-13 420.194375966368 64.0424433000857 6.5611858997548 7.24721225509126e-10 -427.240746145391 195.965524071088 -2.18018321421887 0.0307235236983598 HEATR1 essential 3.67078186032106e-09 1 9.18511681210266e-06 6.5611858997548 -2.18018321421887 2.32431393733554e-08 534.9664925539 119.015030576767 4.49494899897402 1.33922756302034e-05 -317.63277024524 186.319354410504 -1.70477603494387 0.0902016758834847 PTBP3 other 0.00024203081029475 1 0.13429774001968 4.49494899897402 -1.70477603494387 4.42895776250185e-11 889.754485776807 191.242602383192 4.65249099671844 6.92402608942575e-06 -896.796021483987 306.098585779465 -2.92976205427523 0.00389821644401418 RAD23B other 5.31696379388348e-07 1 0.071248228460191 4.65249099671844 -2.92976205427523 1.07124142539733e-07 193.442746604001 55.6008834515079 3.47913080864464 0.000650198204157244 -223.193257293517 87.2879004900886 -2.5569781841512 0.0115003974683752 FKBP15 other 0.00106352848713447 1 1 3.47913080864464 -2.5569781841512 2.91479238125239e-07 253.652217833127 62.8685389119886 4.03464470819374 8.51773299472526e-05 -181.912010373006 100.979816966259 -1.80146900477934 0.0735478970508393 CTNNAL1 other 0.00278304376561978 1 0.784909095463933 4.03464470819374 -1.80146900477934 4.72718664150519e-09 157.840452569774 34.3572332305604 4.59409672224062 8.87085910364963e-06 -115.356348081554 55.1847900894586 -2.09036489754792 0.038196499760016 FAM206A other 5.1408154726369e-05 1 0.0905005045754336 4.59409672224062 -2.09036489754792 1.19198274430949e-05 294.677661189379 198.979045749152 1.48094820778703 0.140663457277702 -819.372726304296 270.456347340761 -3.02959325732492 0.00287277176853209 WDR34 other 0.0976829858961627 1 1 1.48094820778703 -3.02959325732492 4.26966497945839e-08 1273.23672401396 360.173989244387 3.5350601710165 0.000538674532178649 -1043.13036965032 489.555777953581 -2.13076919245192 0.0346960871475529 SET other 0.00043657324414962 1 1 3.5350601710165 -2.13076919245192 4.48811854808561e-07 437.423127682707 192.351929227802 2.27407715346939 0.0243160591791021 -761.017483550255 265.28181695465 -2.86871332640319 0.00468888539543396 PTPA other 0.00422242193003895 1 1 2.27407715346939 -2.86871332640319 6.25281756284826e-11 290.31594676084 61.7397826036627 4.70225087484543 5.6748588120154e-06 -169.429967849943 84.2626475729319 -2.01073634320945 0.0460985220082206 GLE1 essential 7.46648945179711e-07 1 0.0588709853158477 4.70225087484543 -2.01073634320945 4.41715779855252e-11 463.30066893926 111.17344410922 4.16736813950012 5.09005686805409e-05 -540.865279353542 164.378281887143 -3.29036946453111 0.0012371229787537 RAB14 other 5.30323965294215e-07 1 0.481213976305833 4.16736813950012 -3.29036946453111 2.84117382920007e-08 193.681330227512 33.8597382867381 5.72010712508583 5.28353523986371e-08 34.8404816991527 50.0641645972065 0.695916569855174 0.487516561543789 CNTRL other 0.000294231961751959 1 0.000622875969427533 5.72010712508583 0.695916569855174 5.76537313669683e-09 103.219875248086 24.818805972056 4.15893799904409 5.26201640670743e-05 -98.3716567432191 41.2014026274598 -2.38758028780449 0.018156429953829 TRIM32 other 6.23409797271028e-05 1 0.496681728629114 4.15893799904409 -2.38758028780449 6.7699678556924e-10 439.937216636568 79.9903495566672 5.49987866129907 1.53498124897689e-07 -118.022496563249 119.147818187789 -0.990555247744732 0.323446606842241 FBXW2 other 7.70693140692023e-06 1 0.00176660991944751 5.49987866129907 -0.990555247744732 0.000312371044200341 239.021622902352 74.0708857620218 3.22693080342378 0.00152497625318027 -77.4529323292778 110.342135928543 -0.701934321621581 0.483766061992754 PHF19 other 1 1 1 3.22693080342378 -0.701934321621581 5.25491044181683e-05 324.313496245554 97.3353530009592 3.33191883777684 0.00107551127639076 -137.216462477496 139.723062040796 -0.9820602302391 0.327581117353142 NEK6 other 0.399268095369242 1 1 3.33191883777684 -0.9820602302391 9.33606679376894e-08 89.2682900096817 39.4497447367649 2.26283568132923 0.0250080951612753 -232.697395100743 62.2199015754305 -3.73991904854814 0.000257031871716198 BSPRY other 0.000931179302010514 1 1 2.26283568132923 -3.73991904854814 6.516900347863e-11 290.564825253665 68.8690345738521 4.21909247097222 4.13409958786789e-05 -290.656144306651 99.7338403857107 -2.91431818109648 0.0040857688129892 PPP6C other 7.77596549507013e-07 1 0.39397969072381 4.21909247097222 -2.91431818109648 7.59273344668137e-07 90.4718439080088 72.4330245837537 1.24904136514964 0.213520933650497 -444.242543019083 107.668212440503 -4.12603249324464 5.98792961759781e-05 NDUFA8 essential 0.00699062968435953 0.861064279010565 1 1.24904136514964 -4.12603249324464 0.000108943405164944 99.5213543284073 75.0570238950378 1.32594325172793 0.186772210072998 -356.675036077672 118.379489410023 -3.01298001752888 0.00301383538037156 HDHD3 other 0.795940518135078 1 1 1.32594325172793 -3.01298001752888 2.43853864881333e-08 148.236604958408 34.551441472324 4.29031608065172 3.11843209014177e-05 -98.1424064182024 51.3590584121789 -1.91090743195809 0.0578506003585363 RBM18 other 0.000253583634090098 1 0.30180185768392 4.29031608065172 -1.91090743195809 0.0260455821871903 2.02340803576546 2.77432021841474 0.729334711377205 0.46687674145379 -8.49926291052903 4.35540898129487 -1.95142705243772 0.0527747916326227 SLC46A2 other 1 1 1 0.729334711377205 -1.95142705243772 3.34526564983083e-12 455.476328072905 68.0967641935157 6.68866330826739 3.68922710196938e-10 -57.7496851152106 106.606241921657 -0.541710167005511 0.588781270163445 HSDL2 other 4.17689869037878e-08 1 4.71667684986786e-06 6.68866330826739 -0.541710167005511 6.31920315193023e-10 358.300342554853 87.7452140736454 4.08341749846468 7.05152645171041e-05 -334.312397016736 127.069694372536 -2.63093728734893 0.00936359698799316 MAPKAP1 other 7.20578735414605e-06 1 0.655509898951 4.08341749846468 -2.63093728734893 0.422874651047711 31.0730999669764 28.044803038482 1.1079806809247 0.269564679839224 49.8428865719991 42.0828815161139 1.18439813948847 0.238045428997654 NR4A3 other 1 1 1 1.1079806809247 1.18439813948847 6.44149065240771e-10 80.8595945354661 14.4350405701379 5.60161879300445 9.44749906854486e-08 -13.5192441700293 21.6225927336197 -0.625236961014811 0.532734969601074 INVS other 7.34265519467955e-06 1 0.00109912204163451 5.60161879300445 -0.625236961014811 7.11990491411849e-05 37.2513520829247 61.6396168704209 0.604341071120457 0.546489240640121 -320.699198038351 91.9241229638968 -3.48873818643127 0.000629885027051884 GALNT12 other 0.53235529042864 1 1 0.604341071120457 -3.48873818643127 8.16842141431129e-12 450.361333677953 69.7420984889522 6.45752484418424 1.28274004849288e-09 -37.3856960621651 100.334851292308 -0.372609273653561 0.709945013906154 DENND1A other 1.00692130774215e-07 1 1.61291733697494e-05 6.45752484418424 -0.372609273653561 3.97144287473749e-09 132.797298158415 49.9316939553709 2.65957926997448 0.0086353323808031 -283.19758278638 74.0380813341626 -3.82502595533506 0.000188282687416445 ALG2 essential 4.33721276350082e-05 1 1 2.65957926997448 -3.82502595533506 0.874602826249015 13.9069441917105 149.252659858302 0.093177194998826 0.92588880704957 -242.009476351115 547.9973365077 -0.441625278497525 0.659404953616405 CSF3R other 1 1 1 0.093177194998826 -0.441625278497525 1.96334462043433e-35 371.094698238538 28.4414697047914 13.0476625185098 1.24653069240932e-26 -160.716209679773 83.2975245425449 -1.92942360006972 0.055528906739267 KDSR other 2.85568475042173e-31 1 1.80422852419325e-22 13.0476625185098 -1.92942360006972 2.97612709746822e-30 286.37786378376 24.9706243255797 11.4685904545205 2.29880094378227e-22 -128.366709569274 73.132338595436 -1.7552660291556 0.0812152562679211 VPS4B other 4.31359861507044e-26 1 3.30912395857458e-18 11.4685904545205 -1.7552660291556 0.176109045144992 -12.6616827338495 90.8476221257898 -0.139372747877956 0.889338897151243 -227.294139572709 166.170719037213 -1.36783508484312 0.173369393658534 ONECUT2 other 1 1 1 -0.139372747877956 -1.36783508484312 0.000160816836757225 86.2621045353465 30.849894462286 2.79618799476938 0.00589820332779237 -77.8239866948218 46.3695906467925 -1.67834103362319 0.095511384054527 C19orf25 other 1 1 1 2.79618799476938 -1.67834103362319 4.40664307104279e-13 270.868978856447 50.6645097522982 5.34632586362211 3.75956934452879e-07 -165.514148693763 88.3724858073234 -1.87291493706118 0.063258865497162 ZBTB45 other 5.65548571737632e-09 1 0.00421898871843021 5.34632586362211 -1.87291493706118 1.62708097460215e-08 553.316466531732 101.019630079139 5.47731630078491 1.69478518886515e-07 -27.6908321933241 153.053695583257 -0.180922336359145 0.856663374504051 YLPM1 other 0.000171299085006114 1 0.00194493548274165 5.47731630078491 -0.180922336359145 2.20552950184126e-07 44.3032367551715 27.6762334182685 1.60076828684094 0.111451404761301 -161.758889612012 42.1967644391286 -3.83344296090187 0.000182894068613277 DCAF4 other 0.00213164426352958 1 1 1.60076828684094 -3.83344296090187 2.94029397769855e-12 122.195496783416 34.3085151999799 3.56166671950548 0.000488128270261406 -234.503006349073 51.4337682478153 -4.55931996308736 1.02708863215487e-05 FCF1 essential 3.68036597188527e-08 0.149164082047852 1 3.56166671950548 -4.55931996308736 0.969186169266937 7.49457550358239 30.0757463872942 0.249190008689146 0.803548021524135 6.08316997882009 44.7895620372169 0.13581668813295 0.892144728389422 PGF other 1 1 1 0.249190008689146 0.13581668813295 0.100885079570743 4.12438963654297 38.1052172287325 0.108236875065839 0.913945998051413 -128.811064315076 66.684246050421 -1.93165660473509 0.0552029292275907 IFI27L2 other 1 1 1 0.108236875065839 -1.93165660473509 0.000324132561345637 60.824128339857 28.8314086579085 2.1096481639711 0.0364745777847359 -86.7067440648399 43.3618702723483 -1.99960803167045 0.0472676099125022 BBOF1 other 1 1 1 2.1096481639711 -1.99960803167045 7.24929320350616e-07 360.237104825291 76.0083679579627 4.73944007092119 4.8609851981085e-06 -41.8639136792215 113.793462116428 -0.367893839422765 0.71346084722206 NEK9 other 0.00668747298023443 1 0.0507311915896679 4.73944007092119 -0.367893839422765 0.00242815527238836 64.6816049589546 18.9865429944883 3.40670784448393 0.000842794675079421 22.6102362204725 28.3318183513798 0.79805100894173 0.426094170271831 ACYP1 other 1 1 1 3.40670784448393 0.79805100894173 6.07050924085731e-06 76.7994539870324 31.4864711476977 2.43912547794826 0.0158516630756919 -132.079285633034 47.4529625254694 -2.78337280969851 0.00604940447006883 IFT43 other 0.0511743929004272 1 1 2.43912547794826 -2.78337280969851 1.62832329750468e-06 112.048123862619 27.8501335310999 4.02325266187669 8.99600678974817e-05 -38.3557121811724 41.6279606774638 -0.921393014621951 0.358295854021247 DNAL1 other 0.0145702368660719 1 0.827452704521036 4.02325266187669 -0.921393014621951 2.51298688922111e-05 1158.06323306894 283.353844634764 4.08698613058049 7.03370201697297e-05 -165.635231642557 455.306892764343 -0.363788104847089 0.716518449337855 IRF2BPL other 0.199103951232988 1 0.653993613538147 4.08698613058049 -0.363788104847089 2.65880825855225e-09 148.83815726001 34.4294866131079 4.32298508927939 2.76185260644152e-05 -105.540279787747 51.7653881196433 -2.03881944328933 0.0431895072799211 ACOT2 other 2.93452667496412e-05 1 0.268617784502502 4.32298508927939 -2.03881944328933 0.652754454383731 228.556512112099 440.411979121087 0.518960707127494 0.604533108261697 -284.726632296726 661.570220567362 -0.430380061624516 0.667520893404409 LTBP2 other 1 1 1 0.518960707127494 -0.430380061624516 2.50002774228716e-09 517.542314032009 93.2652828334144 5.54914217068763 1.20438870991498e-07 -95.1463869835698 140.064995105484 -0.679301683564223 0.497953386484144 AREL1 other 2.7630315990246e-05 1 0.00139407993172659 5.54914217068763 -0.679301683564223 1.26885996329112e-09 118.50184285475 20.991440585194 5.64524585026972 7.93939037422456e-08 -21.7384701912261 31.3235369791196 -0.693997941730432 0.488749783510052 MLH3 other 1.4248028527796e-05 1 0.000927162007901945 5.64524585026972 -0.693997941730432 1.42546709017525e-05 227.467450476949 62.7461544593088 3.62520145556431 0.000391106782001203 -111.720509612103 94.5641352505966 -1.18142580499512 0.239243109561794 TTLL5 other 0.115819201076739 1 1 3.62520145556431 -1.18142580499512 0.0144331912251834 5.81334806701663 11.3377157342133 0.51274420732511 0.608860206469618 -39.5677018162514 17.0869640277039 -2.31566601018755 0.0218874637813354 FLVCR2 other 1 1 1 0.51274420732511 -2.31566601018755 2.48659344773646e-07 199.70134810591 43.2673373819678 4.61552201243467 8.1367389446017e-06 -47.9596028516268 65.307197379423 -0.734369331040041 0.463826066250408 ABCD4 other 0.00239160557803292 1 0.0832307026643308 4.61552201243467 -0.734369331040041 4.64913124493855e-06 431.623782275411 126.232487690573 3.41927652834844 0.00080372787446043 -343.017144344138 188.646136417094 -1.8183099365774 0.0709599169558934 DLST other 0.0396291947318562 1 1 3.41927652834844 -1.8183099365774 0.0838127777666816 8.04194080709801 4.56781423185704 1.76056652019944 0.0802714083726256 -4.577891601123 8.09907193025037 -0.565236565442071 0.572724866871785 PPP4R4 other 1 1 1 1.76056652019944 -0.565236565442071 0.268843615547196 71.508888961113 62.9961403917195 1.13513127179634 0.258072595532413 -46.3818678193605 94.9408866822491 -0.488534175740244 0.625861987459981 TGFB3 other 1 1 1 1.13513127179634 -0.488534175740244 0.0146435534783796 21.9344198680636 13.3471260539739 1.64338148747257 0.102370972990755 -26.841635211251 19.9885634359373 -1.34284963985919 0.181322479416867 ZC2HC1C other 1 1 1 1.64338148747257 -1.34284963985919 0.00269974519157119 86.2525480275695 75.0386626301073 1.14944143464736 0.252133195824159 -301.597301657135 119.28659424985 -2.52834196125534 0.0124542350920069 SLIRP other 1 1 1 1.14944143464736 -2.52834196125534 0.00169767345911641 514.182997911083 180.568712562547 2.84757525605648 0.00499904018166405 -106.536892797205 272.934289302974 -0.390338982578119 0.696818383275584 RBM25 essential 1 1 1 2.84757525605648 -0.390338982578119 2.04608532266572e-09 343.910783802757 71.4891094765142 4.810673770048 3.50140455853592e-06 -181.692480535228 107.518211398804 -1.68987633045065 0.093036292716684 ALDH6A1 other 2.27299618494935e-05 1 0.0369223110697613 4.810673770048 -1.68987633045065 0.243475095869729 11.8930047522484 8.53761374938213 1.3930127435326 0.165610597206505 -4.76737202210493 14.9863615765257 -0.318114039739468 0.750826627420999 GPR68 other 1 1 1 1.3930127435326 -0.318114039739468 4.39013930125588e-08 76.8090949033394 47.0636494453863 1.63202590127377 0.104730546681982 -315.471221441124 70.0883768398341 -4.50104904215486 1.33176164220067e-05 EIF2B2 essential 0.000448452729623289 0.193211979050473 1 1.63202590127377 -4.50104904215486 4.62889082210238e-12 199.640722236831 30.5776792895117 6.52896906748931 8.8302725459682e-10 -73.3939872030853 53.2973005805827 -1.37706762638227 0.170464155460301 NRDE2 essential 5.75509995911989e-08 1 1.11694117433952e-05 6.52896906748931 -1.37706762638227 9.75555436279082e-12 127.532368421053 24.6063781941906 5.18289881650124 6.63236851301553e-07 -85.8951842105263 37.1276463959888 -2.31351008071996 0.0219918582385033 COQ6 other 1.19993318662327e-07 1 0.00732876720688216 5.18289881650124 -2.31351008071996 5.71246671542247e-11 212.807332293291 54.4380345828308 3.909166337912 0.000137444785636135 -278.427693471376 82.0654352194813 -3.3927522924448 0.000875824014430242 ZNF410 other 6.83153894497373e-07 1 1 3.909166337912 -3.3927522924448 3.25475026609049e-05 13.2420937840785 3.021353264448 4.38283531419417 2.15829012885769e-05 -12.0037389001402 12.7324801136527 -0.942765179524523 0.347277653305153 GPR75 other 0.253903068257719 1 0.212073588061557 4.38283531419417 -0.942765179524523 7.32915439300949e-11 294.256542848786 43.3794685841562 6.78331368393616 2.7720129539469e-10 -254.440818952911 168.258530687951 -1.51220159781849 0.132659023758445 SUPT7L other 8.7246253894385e-07 1 3.56009623675401e-06 6.78331368393616 -1.51220159781849 0.306320973478705 19.3085737887357 23.1402136597511 0.834416400498501 0.405355851839662 -82.7945755555812 79.8995794956603 -1.03623293236578 0.301739207953431 KLHL29 other 1 1 1 0.834416400498501 -1.03623293236578 3.59687818477837e-10 578.94775842905 85.6621909987238 6.75849813878418 2.89382933761015e-10 -112.722860318637 289.792095891422 -0.388978381111098 0.697843754930587 DNMT3A other 4.15367492778206e-06 1 3.71422995482263e-06 6.75849813878418 -0.388978381111098 0.0395887481093036 287.85881010379 113.957287793452 2.52602370306965 0.0126493794233499 20.0467852809138 417.84878424607 0.0479761723301037 0.961803605408276 TMEM214 other 1 1 1 2.52602370306965 0.0479761723301037 5.47486742304995e-10 93.9538076055394 13.6536819970178 6.88120666835951 1.45522990192798e-10 22.7761388403432 45.4923661566494 0.500658478873474 0.617335671444 ATAD2B other 6.26434330545375e-06 1 1.8871421368202e-06 6.88120666835951 0.500658478873474 7.69901786045143e-11 100.948363514138 14.1568838280017 7.13069095858981 3.71105582749004e-11 -5.67271683262607 48.0125301703655 -0.118150757989576 0.906103178019271 FKBP1B other 9.1549021378628e-07 1 4.89339821412836e-07 7.13069095858981 -0.118150757989576 4.57173689757794e-08 418.687784025264 68.129308958361 6.14548702205618 6.6111245427164e-09 310.662754252603 268.938850879493 1.15514271454891 0.24983284142313 ATL2 essential 0.000466362880921926 1 8.11383315127583e-05 6.14548702205618 1.15514271454891 0.0189062275138445 110.851596221088 41.1256375127617 2.69543775915181 0.00782160085512966 -155.98834396806 267.524882476904 -0.583079758876361 0.560703692798319 YPEL5 other 1 1 1 2.69543775915181 -0.583079758876361 0.0661380575018969 77.4356082654248 34.9857424114043 2.21334757898929 0.0283538566267506 161.586543825184 146.730466750603 1.10124739192598 0.27251846153602 FAM98A other 1 1 1 2.21334757898929 1.10124739192598 5.99309450420874e-16 450.537090087039 49.1759013783937 9.16174543747133 3.59022363363688e-16 -185.990984889394 193.434065807241 -0.961521354127641 0.337837511134287 YIPF4 other 8.16379333363315e-12 1 5.05144465252709e-12 9.16174543747133 -0.961521354127641 0.00167647129399807 121.598933412028 33.4642718309921 3.63369428822927 0.000381611153524723 37.7806032756475 142.042142962743 0.265981648034959 0.790613782653621 CRIPT other 1 1 1 3.63369428822927 0.265981648034959 2.01595143419686e-05 120.606960869147 32.9124634960524 3.66447685946125 0.000343217658722661 -35.2077459818716 61.7335641557341 -0.570317726886037 0.569315508567492 SLC17A5 other 0.161235795707065 1 1 3.66447685946125 -0.570317726886037 0.113580451236885 -20.5879622382505 38.3674131259913 -0.536600217758845 0.592333491958966 -146.003935522455 73.879976101042 -1.97623149366985 0.0499504972092755 OGFRL1 other 1 1 1 -0.536600217758845 -1.97623149366985 2.25869675032164e-05 83.5419247959414 34.1924463405661 2.4432859808813 0.0156843204519845 -128.011423838203 62.8557485647797 -2.03659055474095 0.043404149676532 SLF2 other 0.179905196163119 1 1 2.4432859808813 -2.03659055474095 7.69989432430874e-07 169.233664042098 53.0918820686382 3.18756196706889 0.00173173210266172 -175.026672667564 94.2936982045885 -1.85618631997877 0.0653012848736176 IDE other 0.00708698273609377 1 1 3.18756196706889 -1.85618631997877 0.00382864748913646 36.6537210448498 12.8476956850832 2.85294125446999 0.00493146722635467 3.75058649581086 22.4815008788567 0.166829897880092 0.867724173835608 ELOVL3 other 1 1 1 2.85294125446999 0.166829897880092 0.843251760809516 187.422971712938 335.226583396987 0.55909340426915 0.576894612574509 271.653683088036 599.73857996831 0.452953490339725 0.651207572950033 IFIT3 other 1 1 1 0.55909340426915 0.452953490339725 0.89008832017987 74.3018437334192 156.295421828399 0.475393603115243 0.635167188694906 93.7107672177095 279.621005568958 0.335134933897515 0.737970663194031 IFIT2 other 1 1 1 0.475393603115243 0.335134933897515 7.53522180563537e-09 119.719043624161 20.7077802870557 5.78135570131564 4.03268216039561e-08 -4.34278523489913 39.4022502219499 -0.110216680784386 0.912381971438921 GPAM other 8.08755356398844e-05 1 0.00047787283600688 5.78135570131564 -0.110216680784386 1.16791091859851e-11 38.8513426576758 9.40713516361594 4.12998665182802 5.87885690151643e-05 -45.5923419666898 16.1140851056505 -2.82934722435484 0.00527378565086527 CUTC other 1.43290990602851e-07 1 0.551319200224211 4.12998665182802 -2.82934722435484 0.247181467760476 -7.64432488494196 11.1194410521319 -0.687473844153017 0.492792096716241 -31.7040772671291 19.2823103025649 -1.64420532444766 0.102122068996843 PPP1R3C other 1 1 1 -0.687473844153017 -1.64420532444766 0.75917493823566 -9.18811503728942 18.1051818576924 -0.507485376811372 0.612526439464654 -22.8684147823393 31.0135270976579 -0.737369042557765 0.461998528697927 CNNM1 other 1 1 1 -0.507485376811372 -0.737369042557765 6.08455524741408e-10 377.374953532422 73.6024018941831 5.12720976246084 8.71277693391638e-07 -200.023118726877 131.445261810184 -1.52172178724649 0.130129479915526 MXI1 other 6.94491135939843e-06 1 0.00955094607495914 5.12720976246084 -1.52172178724649 5.30277575821472e-08 117.335122063878 33.4735088430136 3.50531289128262 0.00059856257974654 -155.984404081023 59.8145525109376 -2.60780023477564 0.0100152188247743 SMNDC1 essential 0.000538549906004287 1 1 3.50531289128262 -2.60780023477564 8.12430278369849e-07 31.9165716384378 8.79594974273064 3.62855320595881 0.000385744574311819 -32.618634903434 15.9761209255246 -2.04171181824995 0.0428647353401172 C10orf88 other 0.00746623425821892 1 1 3.62855320595881 -2.04171181824995 0.0197264140329483 -20.1163108998697 55.8257684398163 -0.360340958343571 0.719073429468022 -249.834959829757 98.8636885791839 -2.52706492565928 0.0124849804568041 HELLS other 1 1 1 -0.360340958343571 -2.52706492565928 2.94461421218253e-11 254.946544426841 64.5523023416322 3.94945703218421 0.000118009869116666 -357.93791519612 114.954257293111 -3.11374214078429 0.00219599965527745 TCTN3 other 3.55974412110746e-07 1 1 3.94945703218421 -3.11374214078429 6.29413244945025e-06 70.7540594913062 19.6273272151977 3.6048749132037 0.000421208379767907 -48.2141255927577 35.2586745235636 -1.36744010500269 0.173479836620199 FAM45A other 0.0529651245621239 1 1 3.6048749132037 -1.36744010500269 0.000316053997727096 25.9684254057966 24.2764961859241 1.06969412747683 0.286388449843302 -110.108021734386 42.1708933326934 -2.61099571369581 0.00989718565890049 AVPI1 other 1 1 1 1.06969412747683 -2.61099571369581 2.77722832792926e-09 307.981817536135 50.0095624079141 6.15845855686584 6.045832124595e-09 53.463191164459 87.1025205773273 0.613796142868171 0.540249813076763 WDR11 other 3.06161650870922e-05 1 7.42972309791479e-05 6.15845855686584 0.613796142868171 9.43718873190682e-10 98.3387924571823 27.3274725564931 3.59853229214264 0.000430006122068155 -129.015130326971 47.6532774014347 -2.70737160930481 0.00754315423570192 C10orf76 other 1.06659107048011e-05 1 1 3.59853229214264 -2.70737160930481 0.0471584093351355 5.54063660400806 5.17378143393244 1.07090658443157 0.285876134072154 -10.83295044622 9.06937341924723 -1.19445411997593 0.234125004860192 KCNIP2 other 1 1 1 1.07090658443157 -1.19445411997593 0.00208751027884813 -32.8089399318549 77.6336852850744 -0.422612166501938 0.673156481699989 -415.728008768377 132.983718208649 -3.12615720456927 0.00211061791478366 GOT1 other 1 1 1 -0.422612166501938 -3.12615720456927 0.000604400664638985 -1.86753878368956 23.1870254619575 -0.0805424044905457 0.935911821336469 -131.819344686366 40.8601122246832 -3.22611313354972 0.00153670434204133 C10orf95 other 1 1 1 -0.0805424044905457 -3.22611313354972 0.488460662146113 10.7278767618982 9.01279552103978 1.19029403661213 0.235716193309176 12.7707619671227 15.6561983095205 0.815700064258695 0.415899683214631 SFRP5 other 1 1 1 1.19029403661213 0.815700064258695 3.5853155577836e-06 318.055002092926 61.4783275249984 5.1734491632616 7.0607222649014e-07 200.295897865216 244.750104024388 0.818368999938228 0.414411016559809 GNA13 other 0.0309556145259036 1 0.00778727058595976 5.1734491632616 0.818368999938228 0.156992080776512 39.8453932792339 95.5172973915793 0.417153692235293 0.677146936355607 -733.648961991496 390.568800099771 -1.87841159305117 0.0622150929184108 HOXB8 other 1 1 1 0.417153692235293 -1.87841159305117 9.27515759535696e-11 424.630438773636 58.2734430544302 7.28686030061774 1.48236679973163e-11 331.214429961445 245.094039381834 1.35137692779809 0.178531183021932 KANSL1 essential 1.09994093923338e-06 1 1.96991724016337e-07 7.28686030061774 1.35137692779809 0.00452296288038656 -35.5386797880996 65.7734190264234 -0.540319787448217 0.589757069876086 -891.269835915955 268.946526431707 -3.31392952993678 0.00114687235766568 HOXB5 other 1 1 1 -0.540319787448217 -3.31392952993678 0.421166995693834 7.19162123754544 10.7034705324217 0.671896205605596 0.502643610336914 -48.494038682328 44.8983027658072 -1.08008623255263 0.281770798125395 CRHR1 other 1 1 1 0.671896205605596 -1.08008623255263 0.0682422378948822 106.847622070991 110.791291822905 0.964404515129068 0.336355120726024 -952.352572369594 453.023934831202 -2.10221248624412 0.0371617112568859 HOXB3 other 1 1 1 0.964404515129068 -2.10221248624412 0.631886658680488 343.342627776291 767.182867669938 0.447536881029525 0.655124603658997 -790.603521541344 1282.07419481619 -0.616659725886373 0.538381705538845 DUSP1 other 1 1 1 0.447536881029525 -0.616659725886373 8.96638245939602e-05 284.96608917921 66.2582163567592 4.30084153857758 3.03035010774333e-05 52.4333306284744 111.137413456726 0.471788293407519 0.637754450279704 PANK3 other 0.661270706380456 1 0.293519711436019 4.30084153857758 0.471788293407519 0.275040977672707 10.222086389568 23.3875759961924 0.437073358574324 0.662674410104857 60.2765799807364 37.7126386581015 1.59831245241674 0.112036602256626 MSX2 other 1 1 1 0.437073358574324 1.59831245241674 0.0154379802867395 16.878181527133 5.80763058663537 2.90620783731896 0.00421696494104241 14.396465391107 12.8427711493755 1.12097811474333 0.264100624357267 TEK other 1 1 1 2.90620783731896 1.12097811474333 8.85281474979043e-20 133.490744884727 16.9849120272809 7.85937216927093 7.33287047626969e-13 -75.242339044384 40.7996095382182 -1.84419262576281 0.0671545041005803 RCL1 other 1.24904363304793e-15 1 9.97710357001254e-09 7.85937216927093 -1.84419262576281 7.56958074598093e-17 123.822580920513 19.0010569217524 6.51661544041592 1.05979385204746e-09 -132.027886847856 42.0989041424338 -3.13613595264058 0.00206550395938879 CAAP1 other 1.04301253098871e-12 1 1.33608210927623e-05 6.51661544041592 -3.13613595264058 2.02228481986871e-17 519.048983512086 54.2371411748418 9.56999156424656 3.29370789302211e-17 255.085203002704 119.937930196144 2.12681011407769 0.0350830172634486 MOB3B other 2.80308898882001e-13 1 4.6619141517835e-13 9.56999156424656 2.12681011407769 0.0414855114922295 17.2900541326654 10.3346654754565 1.67301536500887 0.0964511039616158 -15.6378161105276 24.5164592500789 -0.637849697259086 0.524563855066731 CD274 other 1 1 1 1.67301536500887 -0.637849697259086 0.0110560031277688 62.5060526499222 30.0706227205434 2.0786417770863 0.0392770728786707 -17.1502590673574 47.0125074368998 -0.364802049547696 0.715750097652228 GRIA2 other 1 1 1 2.0786417770863 -0.364802049547696 7.59774219216516e-23 268.767072934803 28.3216683020831 9.48980371029327 4.38682876274639e-17 -44.5187619983035 58.0337147345003 -0.767118944599245 0.444192932423348 NUP43 essential 1.08754081738652e-18 1 6.20429191915222e-13 9.48980371029327 -0.767118944599245 1.22780711730573e-09 213.356716581346 40.4662417313233 5.27246187075968 4.48305274298525e-07 -73.0036580525066 83.2949947222758 -0.876447117812026 0.382152106517218 MTHFD1L other 1.37993241913991e-05 1 0.00501115635610891 5.27246187075968 -0.876447117812026 0.965822324892724 9.6488682530471 48.2595277679478 0.199937063193882 0.841795298319893 -2.92438278494549 98.8882306590951 -0.0295726070276951 0.97644645202226 LRP11 other 1 1 1 0.199937063193882 -0.0295726070276951 0.000223231138490225 139.230824737892 33.9126979825285 4.10556614544859 6.50533477173699e-05 95.0535057373687 67.6818276037006 1.40441694769146 0.162195411376967 CCDC170 other 1 1 0.607598267680235 4.10556614544859 1.40441694769146 2.00932137662319e-15 363.152447281873 53.1079385949866 6.83800683832519 1.80194715072216e-10 -138.02602236707 108.823072344651 -1.26835255973963 0.206598579526429 PCMT1 other 2.71459317981793e-11 1 2.33063844474404e-06 6.83800683832519 -1.26835255973963 3.36877773157384e-09 389.615914122777 71.8605886136552 5.42183026383869 2.21914814406851e-07 -48.1769272056357 147.587842678156 -0.326428832696571 0.744540266135875 PLEKHG1 other 3.69824419372176e-05 1 0.00252672207683641 5.42183026383869 -0.326428832696571 0.0702217062184418 -6.77183902213497 3.09114809851079 -2.19071969582998 0.0299655230511055 -3.40335426932627 6.05493864414459 -0.56207906790558 0.574874069328493 MYCT1 other 1 1 1 -2.19071969582998 -0.56207906790558 0.0153789102824789 195.799882502457 176.518452172111 1.10923181170627 0.269082081768567 -476.346401937511 256.549733745305 -1.85674097175409 0.0652835106442582 CYSTM1 other 1 1 1 1.10923181170627 -1.85674097175409 7.60418412779435e-08 238.144658461884 61.4253414031753 3.87697736832723 0.000159803044676507 -193.753104891961 91.2317966183727 -2.1237453615261 0.0353887657609669 WDR55 essential 0.00076429654668461 1 1 3.87697736832723 -2.1237453615261 0.176817698348154 57.2218148796941 66.5022581021897 0.860449201465686 0.390933217799814 -103.180650445912 100.748458039794 -1.02414123703171 0.307439610185742 ARAP3 other 1 1 1 0.860449201465686 -1.02414123703171 0.423055699913041 21.0362246923382 15.9913901639054 1.31547191812127 0.190371972755285 17.4474133428053 37.9839131362933 0.45933691139722 0.646661685704762 PCDHB8 other 1 1 1 1.31547191812127 0.45933691139722 0.0393519635182514 27.9098848749504 12.5738364861209 2.21967932426651 0.0279512118521092 -13.3550072083742 29.8662910468399 -0.44715988294058 0.655408958307316 PCDHB10 other 1 1 1 2.21967932426651 -0.44715988294058 0.0339009667393279 30.4934596855476 15.8753802192699 1.92080184942808 0.0566794449750623 -36.5967956753794 37.491050680127 -0.976147507511128 0.330584207330686 PCDHB14 other 1 1 1 1.92080184942808 -0.976147507511128 0.0604065566927877 17.4376736800318 7.44210859658605 2.34310927524372 0.020445795684001 6.42404671862269 17.6770376800406 0.363411949156854 0.716812262520949 PCDHB12 other 1 1 1 2.34310927524372 0.363411949156854 3.21703773693419e-10 222.95231128731 38.7402686886731 5.75505330329568 5.02008013489793e-08 -33.6411787615218 78.1317351959452 -0.430569968491724 0.667424839837492 ACAT2 other 3.72372118050132e-06 1 0.000592570259123351 5.75505330329568 -0.430569968491724 3.4833592266688e-16 1122.74058059297 162.656172954578 6.90253901957043 1.50641580032343e-10 -605.550369985721 328.046486600356 -1.84592853366979 0.0669559927813222 TCP1 essential 4.75896537547492e-12 1 1.9524655187992e-06 6.90253901957043 -1.84592853366979 9.0813904005202e-11 444.902752369609 70.3245645079469 6.32642029826339 2.63089895250734e-09 -263.210662017485 194.679478983846 -1.35202057962835 0.178363936327329 SNX19 other 1.07732534321371e-06 1 3.27355234331864e-05 6.32642029826339 -1.35202057962835 0.0215077997648827 33.5608966233264 17.8270832414302 1.88257922896387 0.0616314419843897 -64.2355341470187 49.3808511429685 -1.30081869105582 0.19525107939 KCNJ5 other 1 1 1 1.88257922896387 -1.30081869105582 1.77860141783104e-07 53.7680020832022 12.787896940834 4.20460082936011 4.57245949156109e-05 -88.8155004535733 33.9777636934645 -2.61393013545081 0.00990204883014036 MSANTD2 other 0.00173413638238527 1 0.434475100888135 4.20460082936011 -2.61393013545081 0.315751594532741 -1.34466335880627 5.827562709666 -0.230741980103607 0.817819538928502 -24.1059360399841 16.1422933182671 -1.49334023144685 0.137380952750366 TP53AIP1 other 1 1 1 -0.230741980103607 -1.49334023144685 3.8896720971277e-09 42.3971113471038 13.2934039172415 3.18933447076824 0.00172379572670554 -54.7221143684382 21.4878369369017 -2.54665532548148 0.011844478800466 SLC10A7 other 4.24985573332172e-05 1 1 3.18933447076824 -2.54665532548148 1.12059946867183e-07 136.420795892169 28.2660022060181 4.82632085350661 3.35518393713017e-06 -224.374987656759 128.329313416836 -1.74843129510053 0.0824082780684095 NUDCD1 other 0.00111017789361318 1 0.0354206768242832 4.82632085350661 -1.74843129510053 3.78391198663588e-08 274.842006411709 56.9801796377151 4.8234668293287 3.3970893604402e-06 -536.574418425071 257.787545843969 -2.08145981865952 0.0390685791224192 ENY2 other 0.000388380726308307 1 0.0358494840207254 4.8234668293287 -2.08145981865952 7.17370041287879e-07 82.6310394358842 19.3985078256801 4.25965956652066 3.53850338793271e-05 -137.633585792635 81.2339922166964 -1.6942856313831 0.0922193623304935 MASTL essential 0.00661989074100454 1 0.340156330681971 4.25965956652066 -1.6942856313831 6.30728712309587e-05 538.316225621509 147.435328073707 3.65120241298198 0.000359192013031322 -782.406767143179 650.860814712826 -1.20211072698914 0.231202419382468 KIAA1217 other 0.474244918785579 1 1 3.65120241298198 -1.20211072698914 0.00115542598000694 339.588832901529 90.7825505983258 3.74068398236644 0.000257886661690979 363.186448111956 378.503716928478 0.959532051783216 0.338785150422511 PLXDC2 other 1 1 1 3.74068398236644 0.959532051783216 5.65427108006665e-09 147.230875710331 23.2723664544324 6.3264247750056 2.63083849820673e-09 40.9622249745007 102.125509348648 0.401096897687523 0.68890839153057 EPC1 other 6.11509417309208e-05 1 3.27355234331864e-05 6.3264247750056 0.401096897687523 0.0307511016173023 141.020969704733 54.8568706709795 2.57070751539126 0.0112841954373287 59.3344776788573 186.729089885822 0.317757012124561 0.75118304016631 IQSEC3 other 1 1 1 2.57070751539126 0.317757012124561 1.77338064736894e-22 83.1560696536633 7.28738845865601 11.4109560819267 1.41850974097016e-21 5.48237122386163 28.876500147235 0.189855806483064 0.849705200008065 CCDC77 other 2.53398360702548e-18 1 2.03825664680003e-17 11.4109560819267 0.189855806483064 5.76535305921215e-06 37.1778156917287 24.1163009775663 1.54160522902383 0.125262613721959 -173.76055459111 55.5997204048714 -3.12520554646325 0.00213125768177972 TAF12 other 0.0487114679972834 1 1 1.54160522902383 -3.12520554646325 0.032244337532249 1.98549510938879 5.85422297435019 0.339156044805277 0.73495723510865 -20.0139411156176 10.0601016887795 -1.98943725767107 0.0484354212175979 ENOX1 other 1 1 1 0.339156044805277 -1.98943725767107 1.00549908927154e-17 53.5909766060156 8.34410099395042 6.42261840369259 1.58050915418225e-09 -40.0579279613813 14.5404408020401 -2.75493215829886 0.00657833398026707 MTRF1 other 1.39794538381422e-13 1 1.98180042842913e-05 6.42261840369259 -2.75493215829886 0.463636446943409 21.0671398482356 16.95277151062 1.24269591170023 0.215893560716316 20.1340921549958 28.9554788164065 0.695346545040987 0.48789983268548 SOHLH2 other 1 1 1 1.24269591170023 0.695346545040987 0.00523420946747785 -125.439552185616 104.243405093191 -1.2033332187631 0.230706022435588 -573.735683700937 177.941189747418 -3.2242994694783 0.00154387931620143 DNAJC15 other 1 1 1 -1.2033332187631 -3.2242994694783 1.79711475797118e-13 593.143284628107 86.0747716726043 6.89102361937361 1.3566486065922e-10 -63.6671027952563 147.078728763681 -0.432877706589059 0.665713206401076 PROSER1 other 2.32924043780645e-09 1 1.76038723191404e-06 6.89102361937361 -0.432877706589059 6.91050966562959e-13 181.380979749496 60.4244039586231 3.00178351570834 0.00314168831097963 -501.139433855777 103.204504620548 -4.85579031359451 2.96679130847892e-06 UFM1 other 8.81228192561086e-09 0.0432083486166869 1 3.00178351570834 -4.85579031359451 1.28077317335831e-15 88.0042703304865 12.9249586448263 6.80886281719079 2.07035344553805e-10 -29.9139435573709 22.5230490594695 -1.32814804418294 0.186094226668375 WBP4 other 1.73595995916985e-11 1 2.67199815681141e-06 6.80886281719079 -1.32814804418294 2.17044109013882e-08 238.442257705161 58.7728128954105 4.05701626242532 7.87702006209105e-05 -169.207111028593 102.417577075671 -1.65212960372588 0.100545616844419 ELF1 other 0.000226637458632296 1 0.728781896144664 4.05701626242532 -1.65212960372588 0.00955251489658378 33.0788034714282 15.4360105195144 2.1429632630536 0.0337183883186914 -19.5803867241328 26.2134409274836 -0.746959805021387 0.456249330242841 SMAD9 other 1 1 1 2.1429632630536 -0.746959805021387 0.000579481723389587 403.858734357512 188.049655351813 2.1476175194363 0.0332984454330153 -510.746515413574 312.12523394774 -1.63635124579223 0.103794989735475 HSPH1 other 1 1 1 2.1476175194363 -1.63635124579223 4.2563391446066e-19 123.403071143051 15.4108988174661 8.00751939291112 2.66908004657342e-13 -31.6144525021297 26.8550515057353 -1.17722553968582 0.240921720955493 KBTBD7 other 5.98228466774458e-15 1 3.65156841171709e-09 8.00751939291112 -1.17722553968582 5.58037705556681e-06 23.6531663537707 35.4586927658883 0.667062559523495 0.505763888846329 -238.974998855259 61.1297088573731 -3.90931027355016 0.00014013092471324 ALG5 other 0.0472155702671507 1 1 0.667062559523495 -3.90931027355016 7.30093754099501e-09 129.21830212006 32.164084248956 4.01747182105004 9.30161154881991e-05 -119.018178488026 55.4499038863101 -2.14640910346844 0.0334593410306102 EXOSC8 essential 7.84485738779914e-05 1 0.854049864093691 4.01747182105004 -2.14640910346844 0.00084985643739199 305.305186512285 111.019602636287 2.75001152285242 0.00667793831320112 -157.10571853986 161.545803676422 -0.972515007907877 0.332329399765773 ETF1 essential 1 1 1 2.75001152285242 -0.972515007907877 0.421612728867469 -256.76252679482 597.628503293841 -0.429635677314031 0.668053512606313 854.641715978381 979.50464100278 0.872524417141537 0.38426333352161 TGFBI other 1 1 1 -0.429635677314031 0.872524417141537 0.00109024173850172 277.816507666779 89.6526125066703 3.09881106527831 0.00230777901916632 -45.4560635695427 133.435385507129 -0.340659738770075 0.733821032927627 FAM53C other 1 1 1 3.09881106527831 -0.340659738770075 0.00216588853707701 131.985183074511 67.0694685309359 1.96788771352248 0.0509249447131238 -157.199506102484 98.4818087730855 -1.59622886765505 0.112542365725118 SIL1 other 1 1 1 1.96788771352248 -1.59622886765505 0.00206921117179695 101.572883126751 149.652304766266 0.678725819060336 0.498357438703355 -595.34354054867 219.742753047834 -2.70927496944154 0.00752791191224946 PAIP2 other 1 1 1 0.678725819060336 -2.70927496944154 3.21879997401921e-07 525.863559074122 138.767133091618 3.78953969400615 0.000216562809518058 -378.972870272182 202.653746991474 -1.87005113844812 0.0633872461053377 KDM3B other 0.00306333193527408 1 1 3.78953969400615 -1.87005113844812 0.130172623959805 -1391.80626085693 1689.65259517264 -0.823723329182192 0.411378947290973 -4971.98108850784 2458.63144831596 -2.02225554867665 0.0448923276346898 EGR1 other 1 1 1 -0.823723329182192 -2.02225554867665 3.11619794677827e-08 941.750575657152 152.165825667887 6.18897555692033 5.30488466203707e-09 -143.784243699376 625.424076039181 -0.229898798603923 0.818477484940942 SERP1 other 0.000321622790086985 1 6.53084350743384e-05 6.18897555692033 -0.229898798603923 0.0740652338393567 72.3364517936519 32.928082022775 2.19680125139447 0.0295098021435758 141.521042446506 137.438077642862 1.0297076681635 0.304741108045819 PLS1 other 1 1 1 2.19680125139447 1.0297076681635 9.85553001516786e-21 65.2864972954135 6.58176263159283 9.91930292077605 4.03319284149444e-18 -22.9452295334268 25.8293105780206 -0.888340765585589 0.375789300747242 ZFP30 other 1.39840115385217e-16 1 5.73520022060509e-14 9.91930292077605 -0.888340765585589 5.34936979714488e-10 72.0338176550319 20.3781564504518 3.53485448157087 0.000537233574979662 -129.762541326315 41.0900652127853 -3.15800280808361 0.00190759743475688 NR2C1 other 6.12395854377146e-06 1 1 3.53485448157087 -3.15800280808361 3.84706846097584e-18 217.94769277302 29.3796999612205 7.41830900454051 7.14064315660315e-12 -112.743870394525 58.7593999224409 -1.91873760697592 0.0568436547207196 UTP20 essential 5.37089227836836e-14 1 9.54989615764105e-08 7.41830900454051 -1.91873760697592 0.000285541588101988 190.404350237811 317.94052278652 0.598867827759274 0.550158390994137 -1992.39517610635 638.131638159104 -3.12223224326261 0.00215156583292065 TMPO other 1 1 1 0.598867827759274 -3.12223224326261 3.08131855735811e-14 241.960131571485 69.1483281081106 3.49914651867201 0.000608499718897008 -669.829354052062 138.296656216221 -4.84342407386055 3.05001718657487e-06 ARL1 other 4.07005485337025e-10 0.0444174002880898 1 3.49914651867201 -4.84342407386055 0.561961238799304 -0.917819470087953 30.6627856322183 -0.0299326839086522 0.976158999480879 55.421851905568 62.8975702873894 0.881144560152902 0.379595132638276 GLT8D2 other 1 1 1 -0.0299326839086522 0.881144560152902 3.99758241176193e-09 29.200585710007 10.6713097160378 2.73636380978819 0.00693306356793673 -76.6664780857932 21.62656920103 -3.5450134218303 0.000518440346866444 MTERF2 other 4.36535999364403e-05 1 1 2.73636380978819 -3.5450134218303 0.0272895788054016 -32.1586581154414 17.5197725641748 -1.83556367513587 0.0683637091296859 -95.5853876513224 35.5628823210731 -2.68778516848963 0.00798925628684639 SOCS2 other 1 1 1 -1.83556367513587 -2.68778516848963 2.18358128492283e-11 169.876122995393 34.7990846361034 4.88162619137257 2.57942421548922e-06 -154.998233517858 71.3822252840692 -2.17138416322879 0.0314132655300077 NFYB essential 2.65261454492426e-07 1 0.0274502325012362 4.88162619137257 -2.17138416322879 8.00447481002688e-05 -8.01684881602906 22.0224340032478 -0.364031006511213 0.71632777234146 -173.74287961583 44.102581332855 -3.93951724286935 0.000122845998329471 WASHC3 other 0.594812523133097 1 1 -0.364031006511213 -3.93951724286935 2.56384217256045e-07 91.7409802787646 23.6525613739446 3.87869114166322 0.000156353371914746 -71.5836588733757 47.4725511675291 -1.50789576529728 0.133670587951705 APAF1 other 0.00246282679096157 1 1 3.87869114166322 -1.50789576529728 0.0250249840507527 -110.775634547007 103.352897603944 -1.07181934048436 0.285511245268138 -490.980600954113 193.757824870627 -2.53399108542813 0.0122964133186714 DUSP4 other 1 1 1 -1.07181934048436 -2.53399108542813 4.09864394006903e-08 158.733873639906 79.1491942092595 2.00550208028947 0.0466609824467475 -357.844114091254 144.934733238411 -2.46900177821846 0.0146415633109721 TNFRSF10B other 0.000419537193705466 1 1 2.00550208028947 -2.46900177821846 1.55219814368187e-13 1213.98798888682 186.578781448253 6.50657046564273 1.15147259966221e-09 352.652660156978 340.800556971532 1.0347772412427 0.302483874625777 SORBS3 other 2.01537406975654e-09 1 1.4494737084548e-05 6.50657046564273 1.0347772412427 8.99317774499176e-05 -35.5999950434108 48.7196499620519 -0.730711223728823 0.4660586415518 -359.419360434857 99.3482837567629 -3.6177712069474 0.000401597101961961 PTK2B other 0.663066995138243 1 1 -0.730711223728823 -3.6177712069474 6.48794575870546e-06 22.8129689597979 13.2594218045427 1.72051008679595 0.0873747673294045 -48.0733433378087 23.8294518785249 -2.01739190573378 0.0454145975953124 PPP3CC other 0.0545246961561607 1 1 1.72051008679595 -2.01739190573378 9.55526061014964e-05 202.081766485828 61.4768660852521 3.28711886851216 0.00126796711283459 44.0501670447653 114.416558248455 0.38499818312233 0.700799039704357 PDLIM2 other 0.702598312664303 1 1 3.28711886851216 0.38499818312233 8.90929497346513e-13 201.095612593039 44.2888033780333 4.54055195116833 1.12032897444303e-05 -142.962788411496 90.3129765643952 -1.58297061895153 0.115466454899485 EPHX2 other 1.13299504177556e-08 1 0.113220446157213 4.54055195116833 -1.58297061895153 9.15184073430167e-13 135.822345454242 26.1953285343633 5.18498347047141 6.69870405946861e-07 -137.563393965714 60.0388668455596 -2.29123901221477 0.0233054676474076 UBIAD1 other 1.16347351255177e-08 1 0.00739871863368308 5.18498347047141 -2.29123901221477 1.94454057770521e-07 365.972544097263 81.6854229672963 4.48026747983889 1.4401296962378e-05 -106.762454841811 187.135709085781 -0.570508190891951 0.569159182580816 TARDBP other 0.00189028789558724 1 0.143825752763269 4.48026747983889 -0.570508190891951 0.0910290783108356 21.2236908118522 15.5436861747212 1.36542198377424 0.1741116090193 -26.703439660449 37.1875678170941 -0.718074378829748 0.473799373200897 TNFRSF8 other 1 1 1 1.36542198377424 -0.718074378829748 1.43353146995977e-07 313.87761299435 62.4435765328475 5.02657968076572 1.4225677891089e-06 -353.260825262308 266.524629391829 -1.3254340736479 0.187069608008224 ZNF706 other 0.00140858802238247 1 0.0153950286137365 5.02657968076572 -1.3254340736479 0.210040990908232 34.1578977805022 44.6301945915494 0.765353996170338 0.445247526555538 267.412486554631 150.800400405012 1.77328764271466 0.0781836929864008 CRISPLD1 other 1 1 1 0.765353996170338 1.77328764271466 1.49376185333622e-08 208.629442120968 43.0224888665907 4.849311316412 3.12052997769488e-06 -305.963973879228 151.883114402236 -2.01446997635916 0.045784008193502 COPS5 essential 0.000157606813145505 1 0.0330183276939895 4.849311316412 -2.01446997635916 0.386449676294389 39.1659258425701 83.6752034413241 0.468070876816386 0.640431895763146 381.194846114893 276.447250474065 1.37890626678761 0.170032528520593 RDH10 other 1 1 1 0.468070876816386 1.37890626678761 3.10263652134973e-08 305.558174310904 51.9692097808639 5.87960016323774 2.3697287825968e-08 -366.873362347954 197.59157170635 -1.85672576608268 0.0652121099460969 AKAP1 other 0.000320316194464146 1 0.000283775021715967 5.87960016323774 -1.85672576608268 5.75969674735918e-19 187.96786072983 17.883146839062 10.5108939954155 6.32336253120383e-20 62.173083361232 67.9933196191647 0.914399880892237 0.36190009429831 COIL other 8.08776617264177e-15 1 9.0525257996714e-16 10.5108939954155 0.914399880892237 0.00101278917483665 319.528668675372 227.770382986854 1.40285433288231 0.162622250793406 -3019.79640665105 866.003315276533 -3.48704947588656 0.000632591268454964 SCPEP1 other 1 1 1 1.40285433288231 -3.48704947588656 3.73719512435717e-16 385.428452038855 40.712134550894 9.46716393749959 4.37618041225902e-17 -62.5943826220006 167.655957475508 -0.373350184297178 0.709394685896951 SPOP other 5.10388738133459e-12 1 6.18966957509915e-13 9.46716393749959 -0.373350184297178 0.0599706361053142 450.746249118919 190.950535269901 2.36053933277436 0.0195177279436117 -312.048266371296 780.228145197483 -0.399944898542866 0.689758581643009 TBX2 other 1 1 1 2.36053933277436 -0.399944898542866 1.0083450991769e-12 393.7548153068 48.3907844934263 8.13697937383698 1.16137780392885e-13 28.3376462473812 199.245051927261 0.142225094040109 0.887084561990788 SLC35B1 essential 1.28029577242491e-08 1 1.59596537815902e-09 8.13697937383698 0.142225094040109 8.41312272036937e-13 285.10529811475 35.3484226571776 8.06557341694734 1.75684555625886e-13 216.464338629747 145.544206021973 1.48727554703941 0.138947662133169 FAM117A other 1.07062125780628e-08 1 2.40898662674215e-09 8.06557341694734 1.48727554703941 2.82071989815997e-12 149.456937816797 19.6827446034857 7.59329762325572 3.41841138742107e-12 -90.0956711466676 100.356937299905 -0.897752298652029 0.370795678326356 NCAPH essential 3.53295167244536e-08 1 4.59947252177505e-08 7.59329762325572 -0.897752298652029 1.4625119420166e-06 24.9747622531088 9.61005964363523 2.59881449015248 0.0102458010532103 -30.0882635332849 15.2718048223279 -1.97018387042864 0.0505762866270696 LRAT other 0.0131435948229032 1 1 2.59881449015248 -1.97018387042864 6.34636867792994e-08 40.0425283047163 12.6685923264354 3.16077171582513 0.00189065005424184 -39.0637774611981 19.6918930822345 -1.98374921588623 0.049038521135751 MND1 other 0.0006413640185916 1 1 3.16077171582513 -1.98374921588623 0.00127037642050558 24.7968837194033 13.407552101835 1.84947136741013 0.0662820033689991 -28.3576391548403 20.9594473338985 -1.35297647419244 0.178020688271279 TRIM6 other 1 1 1 1.84947136741013 -1.35297647419244 1.04768043950424e-05 50.4441816847427 13.2008242266999 3.82129030873047 0.000196882969623894 5.12252089082695 19.5690976700496 0.261765819620132 0.793876046461763 ABCC11 other 0.086444113063495 1 1 3.82129030873047 0.261765819620132 2.93599963809868e-12 130.838208861699 25.5386618287537 5.12314269788361 9.36027654813474e-07 -37.4083076364956 37.9892395121736 -0.984707988811098 0.326396558995301 PAPD5 other 3.67557794693574e-08 1 0.0102457587095883 5.12314269788361 -0.984707988811098 0.072755391273908 87.3373101594577 61.8044529238143 1.41312326260889 0.159747872923279 -33.7907672773442 91.9352854423311 -0.36754949000012 0.713741440880838 ADCY7 other 1 1 1 1.41312326260889 -0.36754949000012 1.66959776410826e-36 243.990800060218 15.6099012076077 15.6305153258309 2.71732917653559e-33 -141.848095054893 75.7888069056089 -1.87162327586919 0.0632060191069505 CEP89 other 2.4289308272247e-32 1 3.95045315684744e-29 15.6305153258309 -1.87162327586919 0.287065179717999 17.4640234846067 13.4793613565626 1.29561208596163 0.197336566742847 -29.7198228878554 61.716106245972 -0.481556998580011 0.630906177782214 TSHZ3 other 1 1 1 1.29561208596163 -0.481556998580011 0.000943567982382894 94.7554397793446 76.2400139828988 1.24285706191763 0.215834326679242 -710.816467463477 236.771116858021 -3.0021249082071 0.00313523512901604 ECHDC2 other 1 1 1 1.24285706191763 -3.0021249082071 5.45565358557721e-05 203.940981141951 46.7216042604362 4.36502522484331 2.32922250402298e-05 41.8492317387751 176.22700135043 0.237473437203628 0.812607219325868 PLBD1 other 0.413374872179185 1 0.22805417536889 4.36502522484331 0.237473437203628 0.67400414762588 7.13010841199733 8.36336557791637 0.852540564629212 0.395221125284086 20.31243547183 38.4840749546731 0.527814050246866 0.598378346903269 PRB2 other 1 1 1 0.852540564629212 0.527814050246866 2.06821542116178e-27 202.873303204942 16.1590953679393 12.5547438507886 3.28119833961994e-25 -187.098826651188 98.5471108488807 -1.89857241921682 0.0595284389700786 PYROXD1 essential 2.99084632054206e-23 1 4.74001912141497e-21 12.5547438507886 -1.89857241921682 0.00868162420973415 24.680572454951 8.42815063226272 2.92834970942196 0.00393958448206575 -12.3196201129505 50.885668515512 -0.242103925768312 0.809030325156268 KCNJ8 other 1 1 1 2.92834970942196 -0.242103925768312 0.335507554393156 2.2508840207908 4.68927844477919 0.480006475899682 0.631895135291472 -23.7311558848177 20.6160153209753 -1.15110294183149 0.251451154416331 BCL2L14 other 1 1 1 0.480006475899682 -1.15110294183149 6.10886491104935e-12 214.586711441592 37.30937389364 5.75154951818079 4.94800032639403e-08 -71.4731350443752 61.5750534168885 -1.16074824264419 0.247625831599966 PSPC1 other 7.56582919233462e-08 1 0.000584259878540607 5.75154951818079 -1.16074824264419 2.14786933488104e-08 58.7836816524908 11.707082566117 5.02120671999227 1.4043436658148e-06 -8.32616646415552 23.6300745862537 -0.352354641698808 0.72505405500342 ZNF549 other 0.000224323473334976 1 0.0152048288697769 5.02120671999227 -0.352354641698808 0.00307417193820875 46.2103594080338 15.4405325869993 2.9927956919661 0.00326476408302954 12.4251453488373 27.6444561163135 0.449462463524647 0.653788222056848 A1BG other 1 1 1 2.9927956919661 0.449462463524647 7.61467620122058e-06 325.497092448277 89.7293687671306 3.62754243031643 0.00039562450790317 -132.542426520037 177.828156145279 -0.745339935998407 0.457272710962569 ZSCAN18 other 0.0635597022515882 1 1 3.62754243031643 -0.745339935998407 2.28547376650706e-06 44.5139862355669 9.99482387513975 4.45370391631283 1.62642495419378e-05 0.1592225503491 19.9297642803402 0.00798918382121388 0.99363609731344 ZNF211 other 0.0201624495681253 1 0.161715433195487 4.45370391631283 0.00798918382121388 0.88523635793953 -19.1182776522377 39.4677391836591 -0.48440265512227 0.628788347427801 -31.0997235700569 93.554716070124 -0.332422831006682 0.740022052294218 PDZRN3 other 1 1 1 -0.48440265512227 -0.332422831006682 7.58074109490757e-10 171.927232963865 26.6997269749878 6.43928805432828 1.42983360753561e-09 -183.655847706148 112.639857367842 -1.63046946256681 0.105032697766878 RNF2 other 8.61247995792449e-06 1 1.79558504434322e-05 6.43928805432828 -1.63046946256681 6.98461703647169e-10 140.765249857825 21.5798307302703 6.52300064895188 9.24108531370539e-10 -133.259921370818 91.245634610222 -1.46045256784141 0.146189747224078 TRMT1L other 7.9439737607174e-06 1 1.16751871853354e-05 6.52300064895188 -1.46045256784141 7.38398038671938e-05 52.3009824764058 12.3563538501266 4.23271970929109 3.96618005718591e-05 -44.9912320585923 55.9889578590457 -0.803573307648616 0.42289011817083 SEC22A other 0.551214135868602 1 0.378690871860111 4.23271970929109 -0.803573307648616 0.000740748082756384 71.4644890530613 23.3657522769351 3.05851436778287 0.00262122582986891 -17.6007675130064 39.7159693415767 -0.443166006138014 0.65826357847324 KIF18A essential 1 1 1 3.05851436778287 -0.443166006138014 5.41739289348463e-08 272.49769409235 65.1568883617221 4.18217783175225 4.83055971053698e-05 -418.175899728383 202.468164625347 -2.06539087516395 0.0405620683038868 DESI2 other 0.00054975703083082 1 0.457937060558906 4.18217783175225 -2.06539087516395 3.39492275827292e-30 885.535600156524 59.2975264115155 14.9337696485187 1.5562312550374e-30 -113.817352528778 383.930225285818 -0.296453222572009 0.767332923927822 MAPK8IP1 other 4.92026155356494e-26 1 2.25886966668678e-26 14.9337696485187 -0.296453222572009 1.4638262653471e-46 200.216522985968 9.29521615990947 21.5397382418612 9.80616503928428e-47 -24.7721339359586 60.0081037940281 -0.412813143054587 0.680361811389281 CRY2 other 2.13455146012914e-42 1 1.43003304767883e-42 21.5397382418612 -0.412813143054587 4.98276758866899e-20 93.864754791313 9.38529223628568 10.0012607416113 5.1036575232135e-18 -192.226692282331 60.7664025923119 -3.16337127231308 0.00192119301231492 PEX16 other 7.04114887954815e-16 1 7.25331807199103e-14 10.0012607416113 -3.16337127231308 0.209810451872879 5.38194405119202 3.89657955284171 1.38119701605144 0.16921924853879 10.4984285633388 6.32012971875318 1.66110966554811 0.0987259470486667 DEPDC7 other 1 1 1 1.38119701605144 1.66110966554811 5.96034561228917e-05 -63.4815936626282 153.096382953034 -0.414651165743758 0.678966929904322 -1089.2695324635 258.863047930614 -4.20789889160027 4.3356968433567e-05 CAT other 0.449648472991095 0.624427059380232 1 -0.414651165743758 -4.20789889160027 1.64797429203487e-13 596.454864999128 82.9527484936859 7.19029659450679 2.97111186096563e-11 49.7281830265436 137.123472138662 0.362652595146201 0.717381785654997 ZMYM2 other 2.13874103620286e-09 1 3.9239474347773e-07 7.19029659450679 0.362652595146201 0.862450402703887 -2.24527597642348 10.4850261978442 -0.214141188973388 0.830731704423771 5.01708623675839 17.332074269036 0.289468309382996 0.772628140570445 GJB6 other 1 1 1 -0.214141188973388 0.289468309382996 0.804991094068673 3.0396852888656 8.79709098187831 0.345533005754657 0.73018433630298 9.57141821404114 14.5418648816282 0.658197438358366 0.511433811856653 GJA3 other 1 1 1 0.345533005754657 0.658197438358366 1.60808155479444e-05 73.180372412336 24.8381389419579 2.94629048429695 0.00371616706169799 -242.476358287759 86.7167695305411 -2.79618763014875 0.00583023299508206 TBC1D15 other 0.129965151258487 1 1 2.94629048429695 -2.79618763014875 0.0135636628795936 83.5303082784899 42.6027499514786 1.96067879124293 0.051756615387744 -113.524661229545 114.867332353686 -0.988311114251297 0.324581316211866 ADGRB2 other 1 1 1 1.96067879124293 -0.988311114251297 3.22943296118265e-09 5.50003800579379 1.5535341769313 3.54033923904915 0.000528812800468452 -12.6806297137741 4.0481905032559 -3.13241921386241 0.00207558261395025 HCRTR1 other 3.54785505115526e-05 1 1 3.54033923904915 -3.13241921386241 8.49144413544292e-10 144.488127626167 41.6110658933533 3.47234862948431 0.00066985232595834 -358.00902257619 106.740131506301 -3.35402455968548 0.00100269250032426 ZCCHC17 other 9.62335363869746e-06 1 1 3.47234862948431 -3.35402455968548 0.2359509870944 -38.5932533118714 83.1890751971847 -0.463922134251319 0.643358622895354 -351.633979989697 213.39546670573 -1.64780435788074 0.101431641887418 FABP3 other 1 1 1 -0.463922134251319 -1.64780435788074 6.94672666539642e-08 492.563432374461 120.194692116907 4.09804645861873 6.79850982026047e-05 -653.965943972863 335.129735454112 -1.95138143467549 0.0528748046134564 KHDRBS1 other 0.000700646851471883 1 0.633077234462655 4.09804645861873 -1.95138143467549 3.1079964617503e-15 177.550185710204 27.3230611622263 6.49818059023579 1.13119666850582e-09 -203.580811410738 76.7137304077518 -2.65377280349499 0.00881775650815505 TMEM39B other 4.18243083857738e-11 1 1.42440284498253e-05 6.49818059023579 -2.65377280349499 0.2129654489605 -6.39615909767664 3.61898844554923 -1.76738864848902 0.0791309748313615 -5.81532293792533 7.94075640670145 -0.732338663986418 0.465067821867247 CCRL2 other 1 1 1 -1.76738864848902 -0.732338663986418 0.686308307006522 -1.95222929936303 9.76185405344583 -0.199985503642509 0.841754056442545 -18.3057324840764 21.4193845276067 -0.854633916323916 0.394072852095433 CCR2 other 1 1 1 -0.199985503642509 -0.854633916323916 0.0122209535553423 832.364428251202 276.578964845524 3.00950012129844 0.00307372760490953 -174.295862935082 1502.31437621057 -0.116018235394063 0.907794308335038 TNFSF10 other 1 1 1 3.00950012129844 -0.116018235394063 2.08710474634573e-07 183.653690061646 31.382644877689 5.8520781399216 3.17640653407454e-08 59.7769173070524 149.665215641922 0.399404210595402 0.690191274246789 ZNF639 other 0.00202303063063292 1 0.000378246490077596 5.8520781399216 0.399404210595402 1.9355350598699e-09 189.068603560023 27.8045305659494 6.79992072196913 2.58746095217022e-10 -35.8354198340014 133.646124729606 -0.26813661755254 0.788977879788484 PIK3CA og 2.15231498657533e-05 1 3.32669854620525e-06 6.79992072196913 -0.26813661755254 1.53254708409331e-11 645.285141181917 112.80161535895 5.7205310325436 5.3209391004038e-08 -136.948644756467 193.625034728706 -0.707287902870362 0.480449628086358 PDS5A other 1.87215951792838e-07 1 0.000627125882373592 5.7205310325436 -0.707287902870362 1.80822902424402e-06 26.5215032572006 12.4081083029953 2.13743325006264 0.0341414399598254 -57.3531249776046 21.4044413003073 -2.67949647332216 0.00817512355226194 LIAS other 0.0161185535221112 1 1 2.13743325006264 -2.67949647332216 0.107838083296439 310.453686503842 206.89462008647 1.5005401608514 0.135508780040731 763.546565760808 376.178607791737 2.0297447806589 0.0440930198295459 CPXM2 other 1 1 1 1.5005401608514 2.0297447806589 0.330969502908874 -50.1266103229374 70.4792702339648 -0.711224877280027 0.478049419399572 -297.507132936342 199.359338015144 -1.49231601538395 0.137716564647222 TMEM54 other 1 1 1 -0.711224877280027 -1.49231601538395 2.40928783353627e-11 28.4598389877316 4.80604757800437 5.92167233590915 2.003027399544e-08 -21.7359923231849 14.1169581213387 -1.53970792690314 0.125683795922839 ZSCAN20 other 2.92150242694608e-07 1 0.000240703802603202 5.92167233590915 -1.53970792690314 0.332740246689046 -14.8133951610637 20.3039956974306 -0.729580294529826 0.466762246309912 51.0041956442351 61.1182941591367 0.834516020873113 0.405291364643375 CSMD2 other 1 1 1 -0.729580294529826 0.834516020873113 0.259128040263132 4.53037706813885 18.6891840947335 0.242406358949371 0.808796430990875 -70.7896407009418 52.864670090947 -1.3390727792145 0.182572648612689 HPCA other 1 1 1 0.242406358949371 -1.3390727792145 0.0404680418524647 31.3048558100085 24.4383971997656 1.28097008793641 0.202117456258479 -143.596140797286 82.9176354359314 -1.73179251967743 0.0853000271601654 LRIF1 other 1 1 1 1.28097008793641 -1.73179251967743 0.192864722943613 -7.61938043067627 7.69722788854106 -0.989886299458447 0.323782454592435 -43.8595579901776 24.9012305109711 -1.761340989589 0.0801652685347475 TMIGD3 other 1 1 1 -0.989886299458447 -1.761340989589 2.28230987209773e-09 133.117447841947 36.6641804131677 3.63072203829052 0.000386428494527476 -495.259811657171 115.228527838506 -4.29806594727376 3.07521557452473e-05 CLCC1 other 2.52628879742497e-05 0.443907368182645 1 3.63072203829052 -4.29806594727376 2.79420873760346e-05 84.2494974925387 47.5769172717123 1.77080614558083 0.0785972852235567 -544.900270034312 149.691541466814 -3.64015404407547 0.000372916690348371 GPSM2 other 0.220155706435776 1 1 1.77080614558083 -3.64015404407547 0.114660388137229 33.4363710238347 18.3627548134778 1.82087989321151 0.0705536505769315 -23.6345612186574 49.0969631187206 -0.481385399775277 0.63092151603583 GTDC1 other 1 1 1 1.82087989321151 -0.481385399775277 0.000219421134143526 814.298646684651 248.049190954271 3.28281113738755 0.00127186878792977 -898.731013882877 630.649369033402 -1.42508826300796 0.156155232615046 CXCR4 other 1 1 1 3.28281113738755 -1.42508826300796 1.3463916840496e-17 101.356868682561 10.920901079176 9.28099869669441 1.47577634602917e-16 -7.28336247707589 27.216737182777 -0.267606011262983 0.78936067319134 ZRANB3 other 1.86973413163968e-13 1 2.08099222553574e-12 9.28099869669441 -0.267606011262983 1.0819106837968e-05 80.0382989698107 17.5964016973834 4.54856057200107 1.08338403710327e-05 -20.7944063158195 48.9599653334473 -0.424722651950362 0.671627846358654 ACVR2A other 0.0890902852331597 1 0.109681799916335 4.54856057200107 -0.424722651950362 8.50765296047758e-13 16.0490457596626 26.9317627002102 0.595915163010749 0.552112449949939 -203.806256306761 38.1415171856267 -5.34342289833096 3.25043042245924e-07 POLK other 1.08251376269117e-08 0.00474725363200172 1 0.595915163010749 -5.34342289833096 0.00156730175648352 81.5431684241822 50.3692935892962 1.61890633386827 0.107526959484298 -84.4024972456846 71.0511717365107 -1.18791140501787 0.236709111471034 SV2C other 1 1 1 1.61890633386827 -1.18791140501787 3.28966759694433e-05 114.713887354927 77.5070076328921 1.4800453643916 0.140890828919355 -378.480256762493 126.593394371301 -2.98973148355911 0.00324842244482582 RPL21 other 0.256561175885688 1 1 1.4800453643916 -2.98973148355911 7.27366826391982e-10 38.2218033617357 31.2884859251004 1.2215932548872 0.223716175662779 -263.03870605578 51.103968001936 -5.14712881093332 7.90867815259934e-07 MTIF3 other 8.26943344925045e-06 0.0115419248959035 1 1.2215932548872 -5.14712881093332 7.90224154560906e-07 236.587715014628 161.904212688174 1.46128202031589 0.145962341237916 -993.651695700392 264.440654763595 -3.75756026087856 0.000242466916325071 GTF3A essential 0.00726848177365122 1 1 1.46128202031589 -3.75756026087856 0.843105775863475 -21.6651179984757 38.069604350228 -0.569092281578858 0.570117242498069 -11.7878834208833 62.1796736095716 -0.189577762902068 0.849888043595037 RASL11A other 1 1 1 -0.569092281578858 -0.189577762902068 4.57667106560611e-06 133.636852027852 57.264923485205 2.33365983737633 0.0208895429953349 -255.247376431416 94.766266801329 -2.69344129558806 0.0078455711536202 UBL3 other 0.039075617558145 1 1 2.33365983737633 -2.69344129558806 5.98086056325825e-09 434.679065913092 66.1084767410096 6.575239475204 8.93030120101053e-10 245.399258838537 254.696922290111 0.963495187268169 0.336960351848215 FYTTD1 other 6.46231983860054e-05 1 1.12914728385577e-05 6.575239475204 0.963495187268169 4.47201972721606e-08 150.8730964467 34.0580351943239 4.42988256914612 1.86185283937031e-05 -134.286042208762 74.4347152906536 -1.80407813322587 0.0733238023666787 MTERF4 other 0.000456503773754216 1 0.184155864342117 4.42988256914612 -1.80407813322587 0.770163503488065 -315.936497673832 515.12636099913 -0.61331844299532 0.540607216076595 -458.69745737698 702.776128415666 -0.652693566030856 0.514966390651427 PAEP other 1 1 1 -0.61331844299532 -0.652693566030856 0.155712909044602 -396.970694477633 300.573226431518 -1.32071209132819 0.188635951989999 -782.685081591634 410.065770983335 -1.90868181880863 0.0582389656384109 OBP2A other 1 1 1 -1.32071209132819 -1.90868181880863 0.000103754627027123 229.896524097995 139.735375756255 1.64522779470684 0.102045057567858 -491.610517660618 190.6380527415 -2.57876384379161 0.010890532026258 MRPS2 other 0.759380115211511 1 1 1.64522779470684 -2.57876384379161 2.28787508749882e-05 1047.24614401752 245.937958319078 4.25817206573225 3.63306603857651e-05 -934.296096863496 855.843031715284 -1.09166758650938 0.276741306766183 FMOD other 0.182114856964906 1 0.348520025080645 4.25817206573225 -1.09166758650938 0.605303043949552 4.10001971479267 4.12201220588993 0.994664622519595 0.321490656531251 4.93316685286194 14.3328592391233 0.344185816002173 0.731185394939931 LAX1 other 1 1 1 0.994664622519595 0.344185816002173 2.79953989983549e-06 536.17244804401 137.707081312012 3.89357208747435 0.000147155834657205 -378.271935430095 222.053683503891 -1.70351569702048 0.0905018974164905 KIAA1191 other 0.0244455824053635 1 1 3.89357208747435 -1.70351569702048 0.453115117042486 -5.40770723061816 4.41523362453116 -1.22478393908145 0.222514736124924 -3.46795918856128 8.93670120605866 -0.388058088616655 0.698505481985391 HS3ST2 other 1 1 1 -1.22478393908145 -0.388058088616655 4.56444199841444e-07 220.31201450903 63.2376256507657 3.48387549725094 0.000645819992116962 -264.365169988613 130.629154869289 -2.02378381957032 0.044744346545411 RBBP6 essential 0.00429011903430973 1 1 3.48387549725094 -2.02378381957032 3.57396138345905e-12 215.776214138043 29.127413213844 7.4080115715695 7.89737827927821e-12 97.0078560806641 65.8656898350835 1.47281317972309 0.142842310057125 ZC3H7A other 4.46066120269524e-08 1 1.0546948691976e-07 7.4080115715695 1.47281317972309 1.13205018762413e-12 76.9548316008818 14.8914313057441 5.16772565516909 7.20040782459667e-07 -65.8327947334529 31.139900769664 -2.1140977686604 0.0361073488356284 SERAC1 other 1.43487361281359e-08 1 0.00793340934114061 5.16772565516909 -2.1140977686604 2.40314809740311e-08 1479.75969341749 365.434988589234 4.0493103824845 8.09256971586084e-05 -2135.22079951909 884.322470631507 -2.41452735900095 0.0169204886107052 ANXA11 other 0.000250047559534794 1 0.747672516048383 4.0493103824845 -2.41452735900095 0.565308678680155 -21.4510364684362 39.7779724352699 -0.539269227544043 0.590484979725221 -78.3152787218641 73.2656650010713 -1.06892196666363 0.286788374138694 LDB3 other 1 1 1 -0.539269227544043 -1.06892196666363 2.00130742917151e-08 201.296407707733 44.7592338331311 4.49731575965298 1.35256559254267e-05 -100.579131790042 82.3736808684173 -1.22101053066581 0.223960296592935 FAM35A other 0.000209516874759965 1 0.135540598028701 4.49731575965298 -1.22101053066581 6.59469811129315e-08 519.240829583349 109.872317761973 4.72585670494576 5.10404452987277e-06 -330.412510692105 261.083664887089 -1.26554264065122 0.207575916022311 FAM213A other 0.000665866668297269 1 0.0531586237786249 4.72585670494576 -1.26554264065122 1.3713165965179e-15 135.212438615822 17.5007177310475 7.72610819131983 1.39554796583838e-12 -17.3143984509851 37.238146974592 -0.46496401829014 0.642622621698276 ZNF205 other 1.85717406666419e-11 1 1.89040927452467e-08 7.72610819131983 -0.46496401829014 4.26513559059751e-10 403.312369289073 62.3946123433435 6.46389734853606 1.29377180223903e-09 144.90309846305 128.391860604585 1.128600347255 0.260833005421981 NAA60 other 4.90789152410055e-06 1 1.62652990977491e-05 6.46389734853606 1.128600347255 0.331623978642414 1659.97199218387 1623.76276508926 1.02229957963879 0.308232032985522 -4237.13079619118 5285.13655288707 -0.801706967036943 0.42394984211784 RPL5 other 1 1 1 1.02229957963879 -0.801706967036943 0.000129468627153159 48.5528182102024 29.6359867100623 1.63830611361819 0.10337323241824 -344.498639587267 98.1748720017178 -3.50903069760294 0.000587930975352187 ODF2L other 0.935151893927268 1 1 1.63830611361819 -3.50903069760294 1.84277598210283e-09 78.0883758771483 15.6615321218893 4.98599851338989 1.65283621339629e-06 -135.743415031018 48.1556468127618 -2.81884730068758 0.00545737311958869 TRMT13 other 2.05082539048224e-05 1 0.0178142687079852 4.98599851338989 -2.81884730068758 6.02326834481821e-07 15.8348695949632 4.23576877878957 3.73836968492132 0.00026116499126374 -36.668047298984 13.0240249615698 -2.81541592611969 0.00551303983230713 LRRC39 other 0.00560163956068093 1 1 3.73836968492132 -2.81541592611969 0.000209688032857243 20.3931749559047 11.1048147493326 1.83642639848003 0.0682103116530805 -111.050139012068 34.2173017593183 -3.24543822283783 0.0014369324840455 RWDD3 other 1 1 1 1.83642639848003 -3.24543822283783 6.79677799591556e-15 399.370810932529 50.5665295993816 7.89792801872274 4.99739340887762e-13 -355.424691080024 172.640744651451 -2.05875323231257 0.041202560303379 ZNF644 other 9.09680766973339e-11 1 6.81794382773173e-09 7.89792801872274 -2.05875323231257 4.78975848280152e-09 40.9636334962939 9.45935032436849 4.33049121679808 2.66051706700946e-05 -115.018246333386 30.515699164927 -3.76914996152476 0.000232387767553637 CCDC18 other 5.20598849495697e-05 1 0.259293993350742 4.33049121679808 -3.76914996152476 1.50208980611464e-16 211.350694870793 25.4456160621741 8.30597672912993 4.61198158955543e-14 -215.768376402299 86.9478715361769 -2.48158318990619 0.0141472120375131 RPAP2 other 2.06086721398928e-12 1 6.36176740463275e-10 8.30597672912993 -2.48158318990619 1.5821861820804e-07 100.907555424289 59.1341824111106 1.70641668337888 0.0906532766534787 -310.273014232182 108.319197176412 -2.86443236582397 0.00497453124653805 PQLC1 other 0.00154927670949313 1 1 1.70641668337888 -2.86443236582397 5.64652903368155e-10 75.6265453178813 14.6090952370418 5.17667549501133 7.0037653925682e-07 -56.9847591273581 36.8785568305583 -1.5452003555665 0.124363698112375 BBS9 other 6.45454733840138e-06 1 0.00772515322800272 5.17667549501133 -1.5452003555665 6.96667180634568e-07 862.983900279512 204.214093407695 4.22587827254724 4.14493682846125e-05 -564.702790730608 479.553722714413 -1.17755897615438 0.240862607858995 ZMIZ2 other 0.00643859808342468 1 0.394971030384072 4.22587827254724 -1.17755897615438 2.56819380680123e-06 302.51816336945 105.113400945913 2.87801708104861 0.0045670405834447 -594.542780738086 254.097817551996 -2.33981852526704 0.0205683075946134 SEPT7 other 0.0225127869104196 1 1 2.87801708104861 -2.33981852526704 0.0036337135232256 24.7431276719608 18.0083784672063 1.373978657602 0.171444824499573 -85.9999379835037 43.5568925692992 -1.97442776356641 0.0501215639156243 EEPD1 other 1 1 1 1.373978657602 -1.97442776356641 2.02083590329466e-14 194.222101169671 30.9056527589877 6.28435524996924 3.26367242781327e-09 -120.771518982553 72.8244389171071 -1.65839271511617 0.0992869682447124 KLHL7 other 2.68104299290102e-10 1 4.04564834151733e-05 6.28435524996924 -1.65839271511617 3.33467605908344e-10 140.368287385922 28.8722745580397 4.8616982740224 2.83003073024295e-06 -136.320013924657 69.7949251659632 -1.95315080001168 0.0526026505831086 HERPUD2 other 3.85788673275363e-06 1 0.0300294560786079 4.8616982740224 -1.95315080001168 6.06198968833374e-08 474.46835699797 204.200814148631 2.32353802787789 0.0215024114271393 -1424.51254403758 435.236984188228 -3.27295840148896 0.00132293918652398 CBX3 other 0.000613473356459375 1 1 2.32353802787789 -3.27295840148896 4.65304902744468e-05 1187.25598377282 528.970644127361 2.2444647863804 0.0262757156902873 -2263.56282694566 1127.45675786837 -2.00767152367357 0.0464860301563131 HNRNPA2B1 og 0.355539476187048 1 1 2.2444647863804 -2.00767152367357 0.164184172758841 12.8228512517659 23.2175016914811 0.552292465492566 0.581559181489601 -62.1208593720169 50.5603249936402 -1.22864833997469 0.22110255361957 WIPF3 other 1 1 1 0.552292465492566 -1.22864833997469 0.0843068017030484 73.6546836483155 35.9648452012516 2.04796331629288 0.0422846129728102 37.7217953985209 75.8975686597317 0.49700927269011 0.619900622533125 NPY other 1 1 1 2.04796331629288 0.49700927269011 0.0504547968470704 16.1442223358476 17.2706567007631 0.934777560319072 0.351375934764724 -55.1132952895643 40.5590787226329 -1.35883992006973 0.176197146456667 FAM126A other 1 1 1 0.934777560319072 -1.35883992006973 0.313667762984456 14.7861750161256 24.9506838920654 0.592616021271775 0.554361220390428 -43.2581310616142 52.7943381951599 -0.819370647316496 0.413919704265425 HOXA7 other 1 1 1 0.592616021271775 -0.819370647316496 0.169278228147413 -68.7119743827418 93.1687327428669 -0.737500364766983 0.461955084567868 238.196288433362 213.767084577963 1.11427953888986 0.266918096187282 INHBA other 1 1 1 -0.737500364766983 1.11427953888986 4.83959044149211e-11 818.205143771933 148.468801312022 5.51095675685017 1.48031949321985e-07 -618.106825236786 374.788105485645 -1.64921676059023 0.101154938396203 FKBP9 other 5.80170102126074e-07 1 0.00170473592839198 5.51095675685017 -1.64921676059023 0.00565612010824807 45.8188910932597 41.7847260440849 1.09654640417933 0.274562647748695 -225.454432772121 105.479522794741 -2.13742370839928 0.0341526018760818 NT5C3A other 1 1 1 1.09654640417933 -2.13742370839928 4.24356722542043e-06 20.6520848397205 21.1327407845314 0.977255390121348 0.329985384496605 -131.465292841648 40.3473397026564 -3.25833856235614 0.00138076133100911 ARL4A other 0.0364013196596564 1 1 0.977255390121348 -3.25833856235614 9.85860795096633e-17 136.929538132055 41.1489765774775 3.32765355352732 0.00110013705720552 -357.272294999222 79.705717161785 -4.48239232668891 1.45067241298747e-05 CCZ1 other 1.35634728189395e-12 0.210318486434923 1 3.32765355352732 -4.48239232668891 0.0264555456838687 -8.72191011235962 4.24347848136127 -2.05536805492689 0.0415436088997279 6.70375972342256 10.1694811440422 0.65920371240867 0.510755898404809 RAMP3 other 1 1 1 -2.05536805492689 0.65920371240867 3.97488169085315e-15 125.626456017221 25.2063606280815 4.98391885567429 1.72984742684897e-06 -116.932529267789 49.3738568585898 -2.36830858895007 0.0191705144500387 MRM2 other 5.34104852799938e-11 1 0.0186200777026023 4.98391885567429 -2.36830858895007 0.38779005105092 20.7787548199002 31.3843756302533 0.662073226012193 0.508907443067996 -43.6933485375719 72.5683008261872 -0.602099650124432 0.547987555987915 TWIST1 other 1 1 1 0.662073226012193 -0.602099650124432 2.03313009532643e-24 340.958106330513 35.7733740039091 9.53105810744201 4.37212314088278e-17 -266.751616117055 88.7621088193887 -3.00524198517901 0.0031178053359014 SMU1 essential 2.92323445106034e-20 1 6.1843681827787e-13 9.53105810744201 -3.00524198517901 0.00136596391542607 127.427418939195 83.5048843426414 1.52598761069267 0.129132836239496 -475.642759789717 206.995376934902 -2.2978424292988 0.0229624101868105 GLIPR2 other 1 1 1 1.52598761069267 -2.2978424292988 2.1956707981838e-10 45.9352363379822 8.89693298947699 5.16304173497912 7.65639509690399e-07 -39.9756227275194 19.6670412787113 -2.0326200652658 0.0438668467963357 SLC25A51 other 2.55971301652267e-06 1 0.00842126896708469 5.16304173497912 -2.0326200652658 3.88582156041156e-09 520.762455475257 175.886042782293 2.96079465566146 0.00357159959306865 -1706.29830147404 435.993630910495 -3.91358538405879 0.000137900283392054 CLTA other 4.24603721906171e-05 1 1 2.96079465566146 -3.91358538405879 0.0630548603940255 19.4058509237095 11.6301869834632 1.66857600409197 0.0973014529917147 -20.9164480993231 28.8293907286575 -0.725525152306856 0.469267907957702 RECK other 1 1 1 1.66857600409197 -0.725525152306856 0.00782672167486549 5.34516945285602 1.75840976361821 3.03977466654728 0.00279734222030649 2.8096351682084 4.32299613950464 0.649927753238834 0.516739654813493 TAF1L other 1 1 1 3.03977466654728 0.649927753238834 1.38172656577581e-09 153.757016815692 33.6215767789627 4.57316495970822 9.81235966242464e-06 -186.240893674549 81.3825910130822 -2.28846109906492 0.0234706811758566 ACO1 other 1.54826346102588e-05 1 0.0997524483282089 4.57316495970822 -2.28846109906492 0.354510420011572 -7.10105776953201 18.5226114801359 -0.383372386617694 0.702013015740487 -64.1486729630622 45.6372218790529 -1.40562177805363 0.162005419677343 DNAI1 other 1 1 1 -0.383372386617694 -1.40562177805363 5.42526882992947e-19 315.626432228071 37.1858011193409 8.48782123088129 1.95498064698825e-14 -140.449745843961 82.2007636183194 -1.70861850500693 0.0896038721768256 DCAF10 other 7.61979007163594e-15 1 2.71135342591647e-10 8.48782123088129 -1.70861850500693 0.0122701762434029 149.763367896877 72.0780399815853 2.07779467831172 0.039528900163329 -160.575498755082 177.827768188464 -0.902983265160826 0.368063997781123 CNTFR other 1 1 1 2.07779467831172 -0.902983265160826 4.41694382349171e-05 192.015789993092 43.4363570292142 4.4206237153808 1.82849443472522e-05 -69.5957515049838 156.179009857484 -0.445615269097245 0.656489046514864 KIAA1549 other 0.338514574632404 1 0.181020949037797 4.4206237153808 -0.445615269097245 2.58496105380944e-06 182.538932201717 36.1571804084446 5.04848359688701 1.22089038695754e-06 -68.6040560544756 130.006129004586 -0.527698629131982 0.598453507169596 TRIM24 other 0.0226520137145321 1 0.0132686367254546 5.04848359688701 -0.527698629131982 3.82224208734115e-12 225.584690401557 30.1229056441082 7.48880911644986 4.81461287615618e-12 -100.165578463603 107.139175240877 -0.934910859994996 0.351279163051541 C7orf49 other 4.76480698607948e-08 1 6.46265486366443e-08 7.48880911644986 -0.934910859994996 0.235070629882944 387.936031321098 234.896107509397 1.65152175331632 0.100643648867546 667.820527538608 859.214389476648 0.777245511385558 0.438190980357714 CALD1 other 1 1 1 1.65152175331632 0.777245511385558 0.800487650614751 -21.7662258002666 237.376544269929 -0.0916949307995462 0.927068751043836 -339.578286371476 528.116243997437 -0.642999131784185 0.521254363308654 PLAU other 1 1 1 -0.0916949307995462 -0.642999131784185 0.0632729683535627 -34.5987520306074 144.153793552121 -0.240012775092857 0.810639534611255 655.568357447583 315.396094736119 2.07855572211848 0.0393169270984027 SRGN other 1 1 1 -0.240012775092857 2.07855572211848 0.00515910883327038 94.0543035678292 54.9940648652817 1.71026280378133 0.0892711189332222 -229.934869122008 126.095641944651 -1.82349576540431 0.0702058252397816 CHST3 other 1 1 1 1.71026280378133 -1.82349576540431 0.422316200641395 -33.9693384218186 26.5099085128123 -1.28138271037039 0.201985333555216 -43.2745889636343 58.6142138176464 -0.738295136027331 0.461458740452345 BICC1 other 1 1 1 -1.28138271037039 -0.738295136027331 0.0722041278100909 -49.7705894253521 36.4087929029627 -1.36699366985336 0.173632443054473 -174.982557372435 78.5766708414223 -2.22690215172862 0.0274141042018585 CISD1 other 1 1 1 -1.36699366985336 -2.22690215172862 0.200131398976745 -82.4732996811901 46.6655865555073 -1.76732589834889 0.079180367042871 -94.6946257780475 100.824540711282 -0.939202153662294 0.349117038533101 EGR2 other 1 1 1 -1.76732589834889 -0.939202153662294 6.83482413254098e-10 165.108288255434 32.9613743470929 5.00914453738475 1.50892216941169e-06 -162.714965862355 71.7168099497788 -2.26885392666377 0.0246940892715895 ECD essential 7.77734638041838e-06 1 0.0163023951183239 5.00914453738475 -2.26885392666377 0.00332116577120182 368.244540679994 130.695848946946 2.8175687571338 0.00549122391303703 -167.471339209846 284.426047408429 -0.5888045090658 0.556878054526961 P4HA1 other 1 1 1 2.8175687571338 -0.5888045090658 0.00130935198938394 33.2968784428939 17.5405522816202 1.89827993487891 0.059530007906335 -83.3829232464192 37.7440040912788 -2.20917004578446 0.0286393670477919 SLC25A16 other 1 1 1 1.89827993487891 -2.20917004578446 0.0704794728511951 106.593664099816 60.4092206205755 1.7645263919116 0.0796258806209983 -90.1071995321172 125.848515613719 -0.715997317033866 0.475077289619757 ZWINT essential 1 1 1 1.7645263919116 -0.715997317033866 1.90706210067401e-06 248.153650538206 81.342150193661 3.0507387614834 0.00268879155235746 -510.63307118891 177.969624498598 -2.86921474733421 0.00469323447061158 VPS26A other 0.0169499679507906 1 1 3.0507387614834 -2.86921474733421 2.65262383779989e-09 164.980394997185 35.7318240967548 4.61718367778958 8.11477979249473e-06 -135.377853095813 72.1617049828207 -1.87603456886228 0.0625307817225337 RBM19 essential 2.92796619216352e-05 1 0.0830385416165986 4.61718367778958 -1.87603456886228 9.52161035402025e-10 122.032255614625 27.0017696701607 4.51941695323332 1.23381433661606e-05 -112.185714802358 53.3624372543677 -2.10233491149574 0.0371615102581647 IFT81 other 1.07603718610783e-05 1 0.124245103697238 4.51941695323332 -2.10233491149574 0.00127169311056478 26.6449679503355 24.227645356054 1.09977538298733 0.273124255338726 -117.715767425428 49.0795457645177 -2.39846896689355 0.0176445447810442 ACADS other 1 1 1 1.09977538298733 -2.39846896689355 0.0618152290905531 15.510892398038 11.1280214300052 1.39385896186496 0.165368255485795 -20.3776500499766 21.9650358652079 -0.927731244102098 0.354998739702502 HVCN1 other 1 1 1 1.39385896186496 -0.927731244102098 1.43669489570918e-14 428.726900245087 78.3225377262855 5.473863752262 1.73627729559425e-07 -518.539026372213 157.348605816208 -3.2954790014339 0.00121789871660103 DDX54 essential 1.91066054180364e-10 1 0.00199040179086624 5.473863752262 -3.2954790014339 4.53532549592668e-05 222.105375918501 92.6515680492834 2.39721119237138 0.0177107331269275 -403.209339023593 180.736961823931 -2.23091798686086 0.0271220418499655 MED13L other 0.346861693928472 1 1 2.39721119237138 -2.23091798686086 0.137424687848728 6.42429374459564 112.060641844878 0.0573287252226219 0.954357655301767 -689.864298068606 363.791150871089 -1.89631962299452 0.0597905415943465 CDKN2C other 1 1 1 0.0573287252226219 -1.89631962299452 5.87607667397164e-07 242.223710414571 76.9704853104546 3.14696873012531 0.00197875749012007 -848.476682486211 242.957044995017 -3.49229092123512 0.000624170092837985 RNF11 other 0.00546886456046541 1 1 3.14696873012531 -3.49229092123512 3.94601297782127e-18 103.652358944896 10.1438605750677 10.218235767126 8.47633762899164e-19 -29.6963111320195 128.826169261608 -0.230514586455762 0.818016841180024 RASSF8 other 5.50823951574071e-14 1 1.20855621914163e-14 10.218235767126 -0.230514586455762 3.51583255553901e-37 2069.17998058769 117.07259842052 17.67433206834 5.38133008485579e-38 522.513740998712 1486.81207400344 0.351432269171566 0.725774222112259 BHLHE41 other 5.11659111807592e-33 1 7.83467847054154e-34 17.67433206834 0.351432269171566 7.65117701235585e-25 357.269026018639 27.9943863964808 12.7621667058061 1.77184502301636e-25 -99.336004825465 355.526333746343 -0.279405476884698 0.780331812585715 SSPN other 1.10138693092862e-20 1 2.56067042726324e-21 12.7621667058061 -0.279405476884698 9.83297225925167e-49 819.923412173453 35.9988579287806 22.7763729003729 9.47184085555079e-50 707.564374082839 456.997312573399 1.54829001093786 0.123732328448755 ITPR2 other 1.43423733373445e-44 1 1.38175214400775e-45 22.7763729003729 1.54829001093786 1.13202630437579e-11 46.0847030645397 6.32386530293716 7.28742641674157 1.83133977872518e-11 -143.586171400489 80.5197286163509 -1.78324211802338 0.0766245680771793 CCDC91 other 1.38990189651259e-07 1 2.42927221647895e-07 7.28742641674157 -1.78324211802338 0.0161572271047405 19.0784304831027 7.11368353584815 2.68193410445662 0.00815162107640319 -5.55187117260149 28.4423813170482 -0.195197128915283 0.845506344842988 NECAB1 other 1 1 1 2.68193410445662 -0.195197128915283 1.07189084599492e-11 186.571726742885 28.2778550551079 6.59780334750615 6.52960486574125e-10 -102.510804330399 94.0646490264408 -1.08979096176273 0.277529927123122 WWP1 other 1.31681790430476e-07 1 8.28802745608536e-06 6.59780334750615 -1.08979096176273 2.51994606100894e-17 589.004245627717 63.619967171134 9.25816645021728 1.84901148103889e-16 -393.026709604559 443.574923078346 -0.88604357270021 0.37699368882332 DDX39A other 3.48962130528518e-13 1 2.6052571767838e-12 9.25816645021728 -0.88604357270021 7.35448292487153e-32 1330.91762611617 90.1308593276383 14.7665032381207 3.59391325937762e-31 -59.4616363758166 628.415743844997 -0.0946214937455216 0.924740097755786 PKN1 other 1.06742965171585e-27 1 5.21979961792006e-27 14.7665032381207 -0.0946214937455216 5.96025647894111e-08 252.772127191713 43.3440620916726 5.83175906903005 3.18362193219193e-08 -12.0106891705203 306.658722146007 -0.0391663054175309 0.968809192420532 ADGRE5 other 0.000603297160798419 1 0.000379073863466093 5.83175906903005 -0.0391663054175309 1.24387175669464e-10 158.5141742405 31.8019956748508 4.98440965344368 1.71536773321204e-06 -359.423761332864 134.416604524907 -2.67395358336301 0.00833880802917815 WDR83 other 1.46689796266998e-06 1 0.0184693643834941 4.98440965344368 -2.67395358336301 3.8245934531221e-13 665.220633713656 89.0077677087886 7.47373685283394 5.73221343459679e-12 -863.002772377608 620.585257590561 -1.39062725358356 0.166371112392662 GIPC1 other 4.91574996529783e-09 1 7.68173922370316e-08 7.47373685283394 -1.39062725358356 2.3439796513194e-06 47.3654175089412 14.2092644497676 3.33341797363169 0.00108393714913099 -38.0882002311108 24.1271187380865 -1.57864685976721 0.116552047960686 SPRYD7 other 0.0206504607281239 1 1 3.33341797363169 -1.57864685976721 5.56683408824633e-10 176.647022236045 55.2219979252131 3.1988524297016 0.00168797701675356 -318.912799826819 93.7661274168045 -3.40115144575827 0.000862959589835219 EBPL other 6.3662314633185e-06 1 1 3.1988524297016 -3.40115144575827 9.33268103770759e-07 300.590792838875 56.0799563913502 5.3600397036906 3.15224552583905e-07 168.193520886616 94.4544561168522 1.78068381102676 0.0770295386222362 ATP7B other 0.00853567007708737 1 0.00355510250404128 5.3600397036906 1.78068381102676 1.85622114350456e-12 739.522778246026 121.035160766472 6.109983029418 8.00139816771113e-09 -184.705384208797 205.430647031601 -0.899113091827939 0.370014562743431 ZC3H13 other 2.33735366390094e-08 1 9.77610828130946e-05 6.109983029418 -0.899113091827939 0.00761848120170366 17.4068672136129 5.51696536579977 3.15515252669879 0.00194108482988382 13.6224551807961 9.30601697894302 1.46383304604107 0.145346082348352 GUCY1B2 other 1 1 1 3.15515252669879 1.46383304604107 5.3403849507818e-18 180.539817720667 62.4901975274688 2.88909020716901 0.00442858250881439 -426.48292071867 86.9948236242051 -4.90239422245356 2.40576998003175e-06 NLN other 7.44449662138983e-14 0.0350592859190027 1 2.88909020716901 -4.90239422245356 0.00920670300652417 1.98144008640355 24.5147139379483 0.0808265636474068 0.935686208126117 -73.1643169836709 34.1278040334599 -2.14383313124801 0.0336367682641848 CENPK essential 1 1 1 0.0808265636474068 -2.14383313124801 0.000344932460415761 266.778489285767 81.9798156864868 3.25419723198696 0.00139612054685321 -551.151996710092 409.142537996305 -1.34709042821421 0.179917221894932 OPTN other 1 1 1 3.25419723198696 -1.34709042821421 0.382065899169771 99.1883159885052 95.77474103423 1.03564170382936 0.301982364935022 453.826378921315 358.561531006955 1.26568619240002 0.207524632431378 ITIH5 other 1 1 1 1.03564170382936 1.26568619240002 1.79370136229187e-07 92.9949873782905 26.6148728485322 3.49409850302625 0.000623367293831426 -206.234421204472 66.8344012853255 -3.08575250527087 0.00241309225640739 ATF1 other 0.00174850008796211 1 1 3.49409850302625 -3.08575250527087 3.1721502488583e-20 262.682240678887 25.6408680975313 10.2446703317419 7.71240965134697e-19 -133.933859515206 83.0921965720843 -1.61187048893353 0.109179749618997 TSFM essential 4.48700652701007e-16 1 1.09986674037859e-14 10.2446703317419 -1.61187048893353 0.0305646633615863 4.8789314834607 9.2706855924973 0.526275153523617 0.599567021190849 83.1773041064213 31.223871979256 2.66390101015279 0.0086717935126793 ARHGAP9 other 1 1 1 0.526275153523617 2.66390101015279 0.269606161256837 27.6655540911399 32.0253688176863 0.863863715313759 0.389079746409424 144.4643509881 91.1194899209484 1.58543853914713 0.115030302602046 NCKAP1L other 1 1 1 0.863863715313759 1.58543853914713 0.0805677635487884 46.4836894387847 26.9306310356078 1.72605273813762 0.0865923772887609 -58.5091740555373 73.9600684902744 -0.79109139904638 0.430258073382694 MMP19 other 1 1 1 1.72605273813762 -0.79109139904638 0.00610216010498253 633.652116359409 298.626931953102 2.12188536450865 0.0356084553910446 -1297.35140531828 787.006939231556 -1.64846247300568 0.101500145379013 PFDN5 other 1 1 1 2.12188536450865 -1.64846247300568 1.82476415417792e-07 139.640350877193 35.4763915100094 3.93614865925118 0.00012701783521388 -246.01656920078 96.4064479617913 -2.55186841131501 0.0117287422561125 SPATS2 other 0.00177713780975387 1 1 3.93614865925118 -2.55186841131501 0.000146371592162343 143.22935138843 56.1857559506078 2.54921107610159 0.0118979084820573 -375.785406874825 154.303935648235 -2.43535853635968 0.0161625575842442 ORMDL2 other 1 1 1 2.54921107610159 -2.43535853635968 0.687534783877287 -214.392246197659 331.050955860857 -0.647611016981233 0.518200840686863 -664.344875114771 860.848559272131 -0.771732574747515 0.441455431920167 NR4A1 other 1 1 1 -0.647611016981233 -0.771732574747515 0.550606096985488 -0.932456674790149 10.1142013835512 -0.0921928128014741 0.926670368918581 -30.5370351566026 28.7795821660788 -1.06106596615552 0.290400108657066 PDE1B other 1 1 1 -0.0921928128014741 -1.06106596615552 0.0723981308182751 79.4741561127172 62.6866782876828 1.26779976677011 0.207035718724413 -238.132408769638 172.135733826165 -1.38339903909853 0.16880920003286 CDK2 essential 1 1 1 1.26779976677011 -1.38339903909853 0.00126274454465533 2289.16444220599 649.464887815872 3.52469315147178 0.000590231442242503 163.733856171529 1599.62103790837 0.102357903710509 0.918634037238541 LRP1 other 1 1 1 3.52469315147178 0.102357903710509 2.51085144591066e-09 140.599570656149 40.7461933291869 3.45061855276273 0.000721915934988631 -436.648895275264 105.954389202842 -4.12110247211496 6.14040455148303e-05 ATG101 other 2.77474193287587e-05 0.882805962366715 1 3.45061855276273 -4.12110247211496 0.000935189659384584 56.9584343061848 16.6164871972064 3.42782644912824 0.000794936257346824 -26.0229796649457 48.1619980760221 -0.540321845116752 0.589815629290786 NFE2 other 1 1 1 3.42782644912824 -0.540321845116752 1.68425242353197e-06 110.171849463073 22.8369274834287 4.82428512079912 3.76489116295159e-06 -39.6326466813652 61.4872799395442 -0.644566595242675 0.52030999063418 IKZF4 other 0.0150533198297803 1 0.0396367741635543 4.82428512079912 -0.644566595242675 1.02206191731084e-12 150.805368057401 24.3839232975767 6.18462280318888 6.25888536015e-09 -226.013457347861 70.6853445083274 -3.19745852439375 0.00170946982262559 SMUG1 other 1.29740539783437e-08 1 7.68778888787224e-05 6.18462280318888 -3.19745852439375 0.0777016254945044 1378.50791695989 1636.28309625095 0.842462969958147 0.400897455793432 -7275.10984048791 4419.32457187566 -1.64620401198552 0.101858103713185 TUBA1B essential 1 1 1 0.842462969958147 -1.64620401198552 7.56861187117113e-06 47.71526717799 10.1532597183691 4.69950227823525 6.06833966814454e-06 -21.9712919039084 33.2703601222345 -0.660386356600481 0.51006829410605 EEF1AKMT3 other 0.0632098069683533 1 0.062807315565296 4.69950227823525 -0.660386356600481 4.72022172101568e-08 54.9454032258063 26.431860726909 2.07875653528505 0.0393775129221226 -235.88188172043 53.1913076808254 -4.43459452314728 1.79541311719501e-05 KBTBD4 other 0.000480848986719867 0.260029681763353 1 2.07875653528505 -4.43459452314728 0.577096464558553 -7.13949781036382 13.6001243690629 -0.524958273661416 0.600357450597133 -19.3463160767674 18.4482968062603 -1.04867762482022 0.295948474029778 SARDH other 1 1 1 -0.524958273661416 -1.04867762482022 5.37449289048515e-08 418.508047289515 92.2871174281286 4.53484797177072 1.14271909425139e-05 -813.065126443344 310.545096290094 -2.61818697560055 0.00971088948557725 ATPAF1 other 0.000545564773313148 1 0.115380346946563 4.53484797177072 -2.61818697560055 1.20543256249308e-05 110.046398233617 32.6186395998883 3.37372740198502 0.000935523873426728 -266.898783907646 107.750367480507 -2.47701042834894 0.0143156099663234 STIL essential 0.098761089845058 1 1 3.37372740198502 -2.47701042834894 0.156756888840003 68.9909280190364 43.677244266946 1.57956229100395 0.116207046887702 -25.4014234724228 97.2836247418587 -0.26110687733753 0.794350117065389 HJURP essential 1 1 1 1.57956229100395 -0.26110687733753 0.483789522827104 -172.123179697775 142.816969937215 -1.20520117303597 0.22993906297754 -240.833118855445 296.250357221384 -0.812937817575266 0.417484761250951 COL10A1 other 1 1 1 -1.20520117303597 -0.812937817575266 2.6439446173514e-11 300.034486438246 79.9723045812958 3.75172990210937 0.000248746567082097 -471.084125567497 167.09843396296 -2.8192013198156 0.00545165917124831 AMD1 other 3.20181693161254e-07 1 1 3.75172990210937 -2.8192013198156 5.02339817735239e-09 120.218618187954 31.9608883458026 3.76142918454711 0.00024114050331371 -130.53411337945 64.9399228595167 -2.01007496824152 0.0462040701041137 NDUFAF4 other 5.45390340115149e-05 1 1 3.76142918454711 -2.01007496824152 1.09042107551424e-13 54.1529320588995 9.32278314051288 5.80866585039115 3.5290666318894e-08 -23.7782922321801 19.0802814941726 -1.24622334526052 0.214587172782836 USP45 other 1.42081866139506e-09 1 0.000419500150532693 5.80866585039115 -1.24622334526052 1.40280815068311e-15 120.314411304167 14.8374074616008 8.10885672686021 1.44754319595213e-13 -89.0808572452692 45.8658191610809 -1.94220574001779 0.053925146622011 METTL8 other 1.89968279765507e-11 1 1.98602926484633e-09 8.10885672686021 -1.94220574001779 1.78020689307705e-09 82.7025117603152 15.4537792352865 5.351604322875 3.03908266484289e-07 -113.804741157343 46.9968585963772 -2.42153932318607 0.016594594076682 TTC21B other 1.98332849957714e-05 1 0.00343142823687411 5.351604322875 -2.42153932318607 0.458695291503841 53.2321964379109 69.1346219853047 0.76997884575439 0.442462127245104 -148.783485194667 202.887166861391 -0.733331178587124 0.464443133714601 NMI other 1 1 1 0.76997884575439 -0.733331178587124 0.854894022604429 -5.84169717657205 10.4489338070676 -0.559071124808997 0.576904743593651 -5.83725297681857 30.6641522866615 -0.190360813573108 0.849270765451899 TNFAIP6 other 1 1 1 -0.559071124808997 -0.190360813573108 1.90104666357317e-07 23.1923635004401 4.0042604987955 5.79192175619354 3.79291644942957e-08 8.59647460141337 12.7241506408137 0.675603020121397 0.500305948333054 ACVR1C other 0.00184952829899033 1 0.000450181253382796 5.79192175619354 0.675603020121397 4.06583552686205e-19 213.977270821805 21.857231192649 9.78977021086597 5.81253032771208e-18 -91.9195633583176 70.5732709218361 -1.30246993171287 0.194663160707075 BAZ2B other 5.71575158366266e-15 1 8.25669933051502e-14 9.78977021086597 -1.30246993171287 0.419834259141325 -16.4627995839492 22.5532600111283 -0.729952103413257 0.466528359470873 26.7132796846773 36.6841513170369 0.728196747794764 0.467598956771262 SLC36A1 other 1 1 1 -0.729952103413257 0.728196747794764 3.42346530901162e-05 159.502685959165 38.3872380590712 4.15509669421172 5.34220246643081e-05 -54.4550826966035 114.66025142312 -0.474925547613296 0.635504260440339 LPGAT1 other 0.266482539653465 1 0.50382311460909 4.15509669421172 -0.474925547613296 0.226784161382951 -3.38267447320537 1.96367171523834 -1.72262728385574 0.0869376706679808 -2.80307565886012 5.87007116166478 -0.477519876959235 0.633660336510361 BATF3 other 1 1 1 -1.72262728385574 -0.477519876959235 0.400655720168717 -25.005326633166 18.5590392778692 -1.34733949633824 0.17990263273809 -20.1912562814073 63.2608180709664 -0.319174757726918 0.750038047845381 G0S2 other 1 1 1 -1.34733949633824 -0.319174757726918 0.557001745192878 -3.03510186529057 9.14571916542682 -0.331860383026415 0.740437290828656 37.6088399720474 36.709576674112 1.0244966948521 0.307176667737731 KCNJ2 other 1 1 1 -0.331860383026415 1.0244966948521 1.58110362632957e-10 148.299226791308 30.9913512167588 4.78518105758211 3.89342006408725e-06 -51.9835724230521 46.6896001057642 -1.11338654229841 0.267233413760776 EXOSC9 essential 1.85605754694828e-06 1 0.0409120580334288 4.78518105758211 -1.11338654229841 3.03525746491544e-05 171.090784882111 78.8130661957116 2.17084289624327 0.0314949585230941 -204.401240745186 119.361711217391 -1.71245233216298 0.0888525559259511 PLA2G12A other 0.237721364652177 1 1 2.17084289624327 -1.71245233216298 9.03625684668316e-07 40.5842239223079 10.145527593942 4.00020832297978 9.72352313120533e-05 -31.2328544813068 26.9683359679775 -1.15813057648025 0.248569462777767 B9D2 other 0.00827269314313844 1 0.891160894974968 4.00020832297978 -1.15813057648025 9.82634026949377e-28 277.0149772753 25.4240318211725 10.8957925801764 6.5134811463665e-21 -198.267184599321 85.2575911760246 -2.32550769807669 0.021332825163911 COQ8B other 1.42138011998227e-23 1 9.34945083749448e-17 10.8957925801764 -2.32550769807669 0.00276108307350603 43.8336522079432 17.991223677467 2.43639081997754 0.0159674509409803 -108.623809655576 63.5695515876495 -1.70873959218991 0.0895007867566271 PFKFB2 other 1 1 1 2.43639081997754 -1.70873959218991 0.798940117184817 -4.67360409483859 9.35173486002592 -0.499757976973445 0.617954206068191 -18.5140878015796 31.9422555623313 -0.579611160065128 0.563018365559878 C4BPA other 1 1 1 -0.499757976973445 -0.579611160065128 0.0133564590689337 38.0867281105991 15.9291117633728 2.39101392948822 0.0179936122512286 -41.1922580645161 49.9691430097724 -0.824353902896837 0.410997129636178 RAB38 other 1 1 1 2.39101392948822 -0.824353902896837 0.602462075286204 2.3888221497626 2.50581398075537 0.953311845216259 0.341916391665547 0.767747840512556 7.01399134964784 0.109459479238038 0.912979644237881 GPR83 other 1 1 1 0.953311845216259 0.109459479238038 8.87991527264162e-07 489.981342398257 94.3635095321739 5.19248748618442 6.94642891308756e-07 -284.675110706058 454.670023192752 -0.626113656464598 0.532231589756715 AGO2 other 0.00813577837279426 1 0.00766468966270081 5.19248748618442 -0.626113656464598 0.000353888633582344 449.324702930257 199.425390759428 2.25309676575883 0.0256561740930222 -522.991352315382 302.274946524863 -1.73018425221147 0.0855877712823829 CKS2 other 1 1 1 2.25309676575883 -1.73018425221147 0.188303945850104 -12.0920019106253 17.6237811828568 -0.686118477366681 0.493643997546659 -73.3452614725968 40.108917984224 -1.82865220900363 0.0693373923737656 DAW1 other 1 1 1 -0.686118477366681 -1.82865220900363 0.0160588773629086 109.132881333726 69.4398062360143 1.57161845991911 0.118104774414495 -250.381775899905 162.068188163503 -1.54491624011559 0.124432403500818 ACSL3 other 1 1 1 1.57161845991911 -1.54491624011559 7.65368214713396e-07 1877.25354924579 338.59037272512 5.54432051371351 1.33141632216392e-07 2288.77952085182 841.53706522353 2.71976079894219 0.00732049160131784 CHPF other 0.00704597978465152 1 0.00153632129414495 5.54432051371351 2.71976079894219 0.0076574468503023 128.915595919349 75.4461498479794 1.70871006909044 0.089736614624316 -316.443533399295 185.472030955922 -1.70615230646015 0.0902130516616695 DNPEP other 1 1 1 1.70871006909044 -1.70615230646015 0.922180597414118 3.46434474616292 10.2223289883456 0.338899750742967 0.735162386654594 -1.59138134592681 25.2260979240572 -0.063084720860025 0.949783590390302 INHA other 1 1 1 0.338899750742967 -0.063084720860025 4.72092486506139e-08 1704.38720069656 290.138690141617 5.87438786555715 2.66588386015913e-08 490.612102742708 721.980616597193 0.679536391233103 0.497852373206527 OBSL1 other 0.000480873406755153 1 0.000318573121289016 5.87438786555715 0.679536391233103 0.000482984085559736 187.216114342568 78.3338354320341 2.3899776298456 0.0181253378917549 -73.4471146487065 124.937884872156 -0.587869041675086 0.557528379660541 SLC12A4 other 1 1 1 2.3899776298456 -0.587869041675086 8.18210284064096e-10 123.645316013776 26.5983019282122 4.64861690597731 7.56281817970762e-06 -16.9465263908328 42.4404409193944 -0.399301374437148 0.690271056580466 ENKD1 other 9.27850462128685e-06 1 0.0775491376147219 4.64861690597731 -0.399301374437148 0.282959947056272 91.2898068568702 96.991776547057 0.941211823381538 0.348080006677051 -383.410613475203 398.23636502411 -0.962771477315965 0.337181382470252 CTCFL other 1 1 1 0.941211823381538 -0.962771477315965 0.274024561554105 142.532000466309 95.1024250051239 1.49872098906657 0.1359799238958 -58.2008238128546 391.708163281002 -0.148582105936615 0.882076521938801 FAM210B other 1 1 1 1.49872098906657 -0.148582105936615 0.0501703255736761 398.195689986634 174.230767803986 2.28544989501863 0.0236420493302374 -76.5084405954191 764.040332649446 -0.100136651595489 0.920365239965961 PI3 other 1 1 1 2.28544989501863 -0.100136651595489 8.7201431745572e-11 73.5803510779022 10.3666874917308 7.09776880383391 4.35562210357704e-11 9.29596367666518 42.6414101322952 0.218003195668821 0.827715223264649 FAM209A other 1.03516819625169e-06 1 5.73069200167631e-07 7.09776880383391 0.218003195668821 1.71705361977414e-09 95.208614388741 14.762147908952 6.44950958193589 1.33743376697024e-09 2.68256614116588 66.342757325695 0.0404349509924108 0.967798069138771 SNX21 other 1.9150299021341e-05 1 1.6810205017049e-05 6.44950958193589 0.0404349509924108 0.320528599504159 3955.77633337605 2617.51757917654 1.51127020687308 0.132755682148297 6915.4744676566 11478.3917164375 0.6024776500486 0.547736630245722 SLPI other 1 1 1 1.51127020687308 0.6024776500486 0.0436339984108548 4.65433008734108 1.84446644540057 2.52340187534845 0.0126234550396999 5.36739100452419 8.04838467436794 0.666890465812098 0.505827278524632 WFDC3 other 1 1 1 2.52340187534845 0.666890465812098 3.47601028539529e-08 104.450693007672 19.4573140971575 5.36819688915495 2.85341661959488e-07 -92.4567991650951 85.3246124242636 -1.08358885599583 0.280229822779881 TTPAL other 0.000357611938161468 1 0.00322607283011397 5.36819688915495 -1.08358885599583 0.0041464112476939 158.650236693961 49.0464926454213 3.23469076251616 0.00149227530009379 28.0625787339577 221.643114179167 0.126611552259968 0.899414089490686 PREX1 other 1 1 1 3.23469076251616 0.126611552259968 0.0813387787513384 29.0971950125419 16.5561489530501 1.75748569882137 0.0808092737096097 -53.1907098522438 72.6023635946623 -0.732630553864701 0.464890238357725 KCNS1 other 1 1 1 1.75748569882137 -0.732630553864701 0.395164091840131 18.1506877927968 21.7671231110785 0.833857910398778 0.405652576851176 -74.1718288425386 97.4702559696382 -0.76096885254557 0.447839294793377 SLC12A5 other 1 1 1 0.833857910398778 -0.76096885254557 0.264695112210598 1.07570692296979 7.4745719080435 0.143915522681936 0.885760344446998 -50.542798439894 34.3913271731902 -1.4696379172972 0.143754143296843 ARHGAP40 other 1 1 1 0.143915522681936 -1.4696379172972 0.878416808651153 42.1813980410421 278.814327768514 0.151288487857278 0.879943612386778 -497.354231294486 1224.45842751682 -0.406183027628886 0.68516475860542 SDC4 other 1 1 1 0.151288487857278 -0.406183027628886 0.068300198110188 99.7853210856367 52.2086870230898 1.91127811817036 0.057876075302287 -178.665531284093 238.913354285066 -0.74782563669887 0.455736144137108 NCOA3 other 1 1 1 1.91127811817036 -0.74782563669887 6.14600549786267e-09 1127.97163309788 185.456470319106 6.08213685484812 8.79159324368211e-09 -163.586127214681 814.462225945176 -0.200851705583817 0.841076160374674 PIGT other 6.6370713371419e-05 1 0.000107283812352653 6.08213685484812 -0.200851705583817 4.36287264318562e-07 8.49315231521321 1.5693233735323 5.41198357104468 2.32424300273489e-07 1.61275793251185 6.88182901023028 0.234350189479335 0.815022396507046 MATN4 other 0.00410895345535221 1 0.00264336156701039 5.41198357104468 0.234350189479335 1.05807019239718e-05 126.38806806954 38.1116064278684 3.31626189278449 0.00113642958401424 -402.466376533197 165.664280591438 -2.42940949670232 0.0162664583064843 NCOA5 other 0.0872378873631475 1 1 3.31626189278449 -2.42940949670232 1.75548288352926e-10 251.144617978424 39.5852482080235 6.3443992231308 2.53303798047971e-09 -246.829762026816 161.041074361579 -1.53271308580953 0.127467085869514 VAPB other 2.05552397914328e-06 1 3.15413889329333e-05 6.3443992231308 -1.53271308580953 1.06771924223094e-09 152.059740995221 25.8341107192866 5.88600639857519 2.41395067394512e-08 -208.777522869509 124.581426215264 -1.67583185722054 0.0958135051188687 PARD6B other 1.20342635791849e-05 1 0.00028902231419145 5.88600639857519 -1.67583185722054 0.226937668710972 386.84085313585 232.243954246154 1.66566597779265 0.0979096386558667 54.8222137849782 944.005054144713 0.0580740680828751 0.953768498307019 ATP5E essential 1 1 1 1.66566597779265 0.0580740680828751 6.93577263257162e-08 395.318482382758 69.776942705221 5.66546006540896 7.07366009568546e-08 -33.822312632201 302.017359151184 -0.111987975549678 0.910979728049592 CHD6 other 0.000699680743173825 1 0.000828184124002854 5.66546006540896 -0.111987975549678 2.01310434157281e-07 438.416506732148 82.5538899410359 5.31067048500424 3.81176814903676e-07 -72.5329854085088 358.305686215887 -0.202433252384407 0.839848736569606 PLCG1 other 0.00195492562610136 1 0.00427604150958944 5.31067048500424 -0.202433252384407 0.0275808655988564 30.132084750625 11.2240885141489 2.68459079885559 0.00805190548764895 27.3784954168547 49.3069942582065 0.555265958283349 0.579513244957373 TOX2 other 1 1 1 2.68459079885559 0.555265958283349 0.00231058432711964 116.246544939105 86.6635059161548 1.34135520724919 0.181779942258452 -999.060251412798 377.200915328754 -2.64861566028294 0.00892425766845984 SRSF6 other 1 1 1 1.34135520724919 -2.64861566028294 1.70514187277844e-09 252.334432717678 41.9794040153891 6.01091031747796 1.29929959978932e-08 -220.776947986051 195.589370766585 -1.12877784268515 0.260758338197167 ARFGEF2 other 1.90208575908436e-05 1 0.000157319195542491 6.01091031747796 -1.12877784268515 0.00389230918731582 345.851343693142 119.675251713017 2.88991532286475 0.00441377686200661 -487.515119654806 574.021764625689 -0.849297273549736 0.397042828356477 ZNFX1 other 1 1 1 2.88991532286475 -0.849297273549736 0.531698089509036 63.7276207973109 66.1625527600462 0.963197732536619 0.337040911069772 -71.0349795990284 268.412193056194 -0.264648855144061 0.79165322470449 EDN3 other 1 1 1 0.963197732536619 -0.264648855144061 9.38251369535146e-12 776.105315494485 112.562844799863 6.89486230447003 1.32899565211467e-10 -629.712473749356 523.5199094546 -1.20284341125706 0.230894989041184 CSE1L essential 1.15498743589777e-07 1 1.72516925601006e-06 6.89486230447003 -1.20284341125706 1.20220993197729e-09 446.348077587199 75.6193630705771 5.90256330472677 2.22461758803122e-08 -583.809180384482 365.483915263735 -1.59735943499238 0.112248886718195 TMEM189-UBE2V1 other 1.35200528950166e-05 1 0.000266776141156704 5.90256330472677 -1.59735943499238 4.29730682298115e-13 215.277261847774 27.1993549357248 7.9147929190416 5.06793151680373e-13 -21.7346718103228 110.865941525035 -0.196044623906567 0.844840578108065 RAB22A other 5.5173122300255e-09 1 6.91367217522366e-09 7.9147929190416 -0.196044623906567 0.90100028482253 21.28584378151 94.7613525837336 0.22462579101223 0.822574073752188 202.340392430463 453.07167428885 0.446596871782064 0.655805982618151 PTGIS other 1 1 1 0.22462579101223 0.446596871782064 2.18391644019811e-11 628.42243564888 95.917058336808 6.55172757115012 8.1864581685386e-10 -815.008649744983 460.065705282417 -1.77150489677269 0.0784675418779161 STAU1 other 2.65280329990864e-07 1 1.0363237395553e-05 6.55172757115012 -1.77150489677269 0.968065596338516 1.91937665477147 8.14438836270297 0.235668606320545 0.814004993041983 6.39170887533088 39.3635019571762 0.162376530479541 0.871223603308995 SNAI1 other 1 1 1 0.235668606320545 0.162376530479541 1.21028010779558e-12 90.371817925775 12.7199182267179 7.10474834153819 4.11407200860753e-11 -113.813116103733 62.4821904397537 -1.82152890772089 0.0704545072830828 MOCS3 essential 1.53318284055544e-08 1 5.41905564973784e-07 7.10474834153819 -1.82152890772089 8.3756586754193e-06 319.671054578862 65.1357424006841 4.90776711520993 2.40410216785095e-06 91.512449715833 264.649500397164 0.345787351113448 0.729993561703206 STX16 other 0.0697608611075674 1 0.0256397496201304 4.90776711520993 0.345787351113448 0.946018703305685 -34.3173940857144 105.136454355391 -0.326408135942191 0.744561643208506 -12.8953868283901 431.677415390991 -0.0298727391534027 0.976207478476024 PMEPA1 other 1 1 1 -0.326408135942191 -0.0298727391534027 0.00309312429131698 188.723768274433 59.1269009631209 3.19184271795583 0.00171594481427109 -97.5317802463454 285.772458057383 -0.34129174277096 0.733352216078348 RNF114 other 1 1 1 3.19184271795583 -0.34129174277096 1.60627284483534e-17 317.672383452143 34.686565405481 9.1583695225687 3.21682182539161e-16 -203.350737216771 166.373942798175 -1.22225111574985 0.223492289030241 DDX27 essential 2.22870357220904e-13 1 4.52703335487362e-12 9.1583695225687 -1.22225111574985 0.137628763757971 -190.705135427794 105.816019918706 -1.80223311720007 0.0734902131127943 -591.436376007843 433.888254172664 -1.36310759814319 0.174864397384349 C20orf85 other 1 1 1 -1.80223311720007 -1.36310759814319 0.674700505151918 8.69840127897676 59.3912808354139 0.146459230321735 0.883750419008154 252.599600319745 286.889693919521 0.88047638403701 0.379973280581012 BCAS4 other 1 1 1 0.146459230321735 0.88047638403701 0.226598141712075 -101.911620923888 218.26633606367 -0.466914059042801 0.641217016490428 -1652.48070197924 957.146008791492 -1.72646669034925 0.0862559334775523 KCNK15 other 1 1 1 -0.466914059042801 -1.72646669034925 5.67698849048166e-07 6.19114308712207 1.22552381928008 5.05183415427942 1.20969197927093e-06 -3.23871971348207 5.38208699907978 -0.601759078594571 0.5482080554928 TP53TG5 other 0.00529038557427986 1 0.0131517711986336 5.05183415427942 -0.601759078594571 0.910360575218738 -45.1394270038959 106.493719386134 -0.423869381819836 0.672256395898537 -91.4725175831082 437.250179510385 -0.209199496923101 0.834570783385385 PCK1 other 1 1 1 -0.423869381819836 -0.209199496923101 0.56233174924353 11.0842814598498 14.2749046808145 0.776487248615196 0.438660095445306 54.835159711731 58.6110117118553 0.935577771312203 0.350964945707029 ZBP1 other 1 1 1 0.776487248615196 0.935577771312203 1.96655109703271e-09 26.4935377261058 4.54656137862651 5.82715936722036 3.16052649225104e-08 -28.4556788338398 20.4020271470266 -1.39474762134051 0.165087563047043 NEURL2 other 2.18641150968097e-05 1 0.000376387099962176 5.82715936722036 -1.39474762134051 2.10248308755294e-07 40.9522182237372 8.20115479070407 4.99346973308638 1.62771820546636e-06 -51.9568336316006 32.6827973779945 -1.58973031074089 0.114001083294207 FASTKD3 other 0.00203730611183879 1 0.0175516854095438 4.99346973308638 -1.58973031074089 7.66355967366227e-13 477.12631582491 66.8927915217007 7.13270152091238 3.67059398023566e-11 -260.906292395062 247.997369092158 -1.05205266229299 0.294434125103217 PEPD other 9.76184231231099e-09 1 4.84077934113478e-07 7.13270152091238 -1.05205266229299 0.996266321156969 0.603440451587837 7.81982103683773 0.0771680641724587 0.938590668288205 -0.202545242036325 29.4459984195981 -0.0068785319876102 0.994520729398806 CHST8 other 1 1 1 0.0771680641724587 -0.0068785319876102 0.00356567234349151 25.908089576191 20.8964881033488 1.239829843563 0.216924247143066 -63.0087898460863 36.1810772943694 -1.7414846256082 0.0835955195629744 ATP8A1 other 1 1 1 1.239829843563 -1.7414846256082 3.19485321031835e-15 1964.85393275948 229.785501463237 8.55081769845187 1.06254105046952e-14 307.484375000001 559.241108428303 0.549824342963911 0.583226170456241 USP22 other 4.29803602384128e-11 1 1.47746333067787e-10 8.55081769845187 0.549824342963911 4.81571069528749e-05 387.357016592641 104.889210383925 3.69301108450336 0.000305416174044567 -19.2120649445188 215.676260625007 -0.0890782550144566 0.929133248777345 HIF3A other 0.36734241183653 1 1 3.69301108450336 -0.0890782550144566 6.00422078882338e-13 37.1624764566405 9.24739457134698 4.01869696052425 9.12977303167573e-05 -115.770623907487 26.2965648599176 -4.40249989016434 1.99161973976712e-05 ZNF576 other 7.67459501227405e-09 0.288326789726086 0.839026141611 4.01869696052425 -4.40249989016434 7.52625414063959e-13 42.0426755819771 7.49017574666314 5.61304260460203 8.79271931257982e-08 -53.769562045108 20.882616001359 -2.57484799996365 0.0109519167653446 ZNF45 other 9.5892004005889e-09 1 0.00102443972710867 5.61304260460203 -2.57484799996365 0.279893079244661 71.0849460524061 52.3296335874708 1.35840710471602 0.176283216938909 -12.8861077810132 149.232763016963 -0.0863490531201141 0.931298971142452 LYPD3 other 1 1 1 1.35840710471602 -0.0863490531201141 0.929712702089435 -18.9589986434207 77.6494744413421 -0.244161326007978 0.807435138837809 32.4697306938651 204.86270260779 0.158495081244869 0.874277076957125 F13A1 other 1 1 1 -0.244161326007978 0.158495081244869 0.0651704534680616 16.7839701560027 12.1339520634331 1.38322370718629 0.168598327142084 -39.4655211394981 35.0851787944486 -1.12484879643089 0.262403250388188 GRM4 other 1 1 1 1.38322370718629 -1.12484879643089 0.312540081962799 8.14160128279958 9.87436225636598 0.824519201485717 0.410945151416867 -69.4535036930727 64.8109179033009 -1.0716327733037 0.285594794023638 TRERF1 other 1 1 1 0.824519201485717 -1.0716327733037 0.372655655894977 31.9365422612972 27.850996221701 1.14669299464458 0.253287037247259 -19.1683420059235 80.2785660848172 -0.238772849849753 0.811599172897341 PACSIN1 other 1 1 1 1.14669299464458 -0.238772849849753 0.00228669225141325 29.4557595566085 9.96992978396994 2.95446008094948 0.00365614727256056 -31.3990231347431 31.8966190541051 -0.984399728431468 0.326558737875233 BTN2A2 other 1 1 1 2.95446008094948 -0.984399728431468 4.88006170342729e-10 137.055109216726 25.6417694087383 5.34499421752151 3.25098037839775e-07 -124.465057802582 72.2304199089069 -1.72316674829733 0.0868919496625569 SIRT5 other 5.59791878000145e-06 1 0.00366157920018938 5.34499421752151 -1.72316674829733 2.92589188734492e-08 192.310143766209 39.450554674482 4.87471330512374 2.68721078113274e-06 -196.839946869758 114.759023379917 -1.71524592204055 0.0883114661804134 MRS2 other 0.000302712774664706 1 0.0285623633926599 4.87471330512374 -1.71524592204055 1.57999226457452e-17 372.702660993408 48.2119791016914 7.73049909872571 1.83615095344074e-12 -296.434092462355 122.066521384776 -2.42846350579568 0.0164225641526802 WRNIP1 other 2.19259430451244e-13 1 2.48376139471929e-08 7.73049909872571 -2.42846350579568 1.01280446910272e-11 194.044177268279 33.0246184583032 5.87574319785946 2.7065566631925e-08 -201.841465119531 100.204913751143 -2.01428709994004 0.0458034289117087 RRP36 other 1.24493925342107e-07 1 0.000323298193418344 5.87574319785946 -2.01428709994004 0.000384779992165928 6.62394111928899 1.82859859133894 3.6224139899609 0.000402883987297191 -3.534231356756 5.88156863413527 -0.600899449892353 0.548845117742882 BTN2A3P other 1 1 1 3.6224139899609 -0.600899449892353 8.73560396033631e-09 418.664828911967 101.162764957804 4.13852694799908 5.73561579764631e-05 -764.823328504952 291.17576634026 -2.62667232963062 0.00949362492421659 SNRPC essential 9.35059047914399e-05 1 0.538516967241012 4.13852694799908 -2.62667232963062 0.101378406844944 29.5375193714959 83.869520747756 0.352184191684274 0.725215021009056 -373.16105117665 214.140058471179 -1.74260273318677 0.0835378530789004 SERPINB6 other 1 1 1 0.352184191684274 -1.74260273318677 1.12186547207803e-20 738.77569910149 73.4065025682974 10.0641724268791 3.77615370713843e-18 -22.9522630900568 206.360176749524 -0.111224284896382 0.911602473360765 XPO5 essential 1.59080523940665e-16 1 5.37006818692156e-14 10.0641724268791 -0.111224284896382 2.77496736409864e-15 283.803073872087 33.4753885736841 8.47796204806991 2.48000952012248e-14 61.9925490473831 102.890836026996 0.602507972926936 0.547783679279316 ABCC10 other 3.73843603291368e-11 1 3.43382118156159e-10 8.47796204806991 0.602507972926936 0.7710201302005 0.943557268722469 2.2950704686363 0.411123441139094 0.681572718973356 -2.43377579411083 6.51089073726236 -0.373800742835712 0.709083919305612 HIST1H1D other 1 1 1 0.411123441139094 -0.373800742835712 1.01295245965446e-07 248.198718266281 56.3217689167529 4.40679905904828 2.0030413600748e-05 -293.140978699321 168.793629915757 -1.7366827103939 0.0845239103436189 PEX6 other 0.00100768510686426 1 0.197600030171379 4.40679905904828 -1.7366827103939 0.0474788412839906 47.6690311738904 24.0081331126401 1.9855367741523 0.0489707656354324 -27.7797247789977 61.567994686588 -0.451203988702416 0.652516607979988 NQO2 other 1 1 1 1.9855367741523 -0.451203988702416 1.40940421593382e-10 165.426123368361 31.1096964161077 5.31751005074767 3.8362402683609e-07 -777.905648097466 213.022792791179 -3.65174842515574 0.000361449539012697 PRICKLE4 other 1.65717747709498e-06 1 0.00430234346096675 5.31751005074767 -3.65174842515574 5.11923587081982e-44 126.592277982104 6.74050337395747 18.7808344509112 1.14001201976857e-41 -124.799174146788 43.9631214991112 -2.83872413721376 0.00514075441168783 OARD1 other 7.46384589965529e-40 1 1.66122551520677e-37 18.7808344509112 -2.83872413721376 0.000110843899310013 8.86244501933623 2.63350730862119 3.36526311900623 0.00096267549110062 -34.4539078528575 17.4864819710833 -1.97031672293104 0.0505722207864333 UNC5CL other 0.809271308862402 1 1 3.36526311900623 -1.97031672293104 7.43690802025902e-16 151.831364851602 18.7997595552714 8.07623972025906 2.5151395957981e-13 -53.7086534231277 57.2932710700972 -0.937433880453714 0.350115973819732 AARS2 essential 1.01164259799583e-11 1 3.44297459268802e-09 8.07623972025906 -0.937433880453714 3.80321273018581e-08 52.2128648153545 9.98452259071038 5.22938020731541 5.70291984900015e-07 -22.0874700386005 28.4875205774081 -0.775338449640888 0.43937677991937 ZNF391 other 0.00039032372249897 1 0.00632738957246567 5.22938020731541 -0.775338449640888 0.00194405971650507 1608.00395174911 725.922841689266 2.21511689590479 0.0282199573907954 -3343.07568616039 2092.42227298219 -1.59770603158211 0.112158259840432 RPS10 other 1 1 1 2.21511689590479 -1.59770603158211 9.52901546212895e-08 130.382355373876 27.8887751302771 4.67508360495646 6.34436507900694e-06 -343.096815292424 150.731217175814 -2.27621604682084 0.0242022712217078 MOCS1 other 0.00094956639080115 1 0.0655372912661417 4.67508360495646 -2.27621604682084 0.433561092425891 -7.78213588724248 13.2035033250747 -0.589399320441223 0.556498185241423 -48.9995012649078 37.8017296264829 -1.29622379052677 0.196929723670011 HIST1H2BJ other 1 1 1 -0.589399320441223 -1.29622379052677 1.42138426893534e-43 174.278355604133 9.23497446291602 18.8715579348882 4.12429246196519e-41 -207.690206821055 63.2030616015092 -3.28607826200773 0.00127047383287044 MED20 essential 2.07180971040016e-39 1 6.00826925859089e-37 18.8715579348882 -3.28607826200773 1.13069974092826e-10 98.323955258661 28.9764809730974 3.39323313103298 0.000883615633642546 -368.142007146186 84.4815472754043 -4.35766175003954 2.42685694751392e-05 TBCC essential 1.33626095382901e-06 0.351093394596839 1 3.39323313103298 -4.35766175003954 0.222599398930436 -144.669601443938 100.57507815466 -1.43842395251706 0.152342964569685 -439.405523806115 291.236352227293 -1.50875919316276 0.133409203996762 SPDEF other 1 1 1 -1.43842395251706 -1.50875919316276 0.0239418610000053 15.108080138415 6.5431460124351 2.30899327474925 0.0222822031653965 -6.51922340981734 19.36544261605 -0.33664210723561 0.73684800695106 TCP11 other 1 1 1 2.30899327474925 -0.33664210723561 5.73289341818386e-08 34.8234652435135 18.2473689175544 1.90841021523999 0.0583851616600805 -226.627597086564 52.6900106369045 -4.30114919976563 3.16794063759841e-05 MAD2L1BP other 0.00058120073473548 0.457133834005451 1 1.90841021523999 -4.30114919976563 1.67781966969724e-15 857.103033692158 115.040981811662 7.45041480170393 7.33488586943672e-12 -613.321813691226 349.062977815751 -1.75705202977716 0.0809909034343873 KLHDC3 other 2.26958666719945e-11 1 9.80600891884995e-08 7.45041480170393 -1.75705202977716 0.573208764600808 -2.23927656992319 2.93934004275841 -0.761829709168915 0.447334392978249 -17.0444669735226 19.1550496371244 -0.889815860382252 0.374961742026554 TREM1 other 1 1 1 -0.761829709168915 -0.889815860382252 8.386815750922e-09 316.11645463442 79.3849178465241 3.98207195031142 0.000107063103196033 -695.904030942728 240.873603308881 -2.88908382397695 0.00444855929692809 MEA1 other 8.98311835081256e-05 1 0.975987248735041 3.98207195031142 -2.88908382397695 4.3342215378971e-06 18.6676599971618 4.31225005408711 4.32898365424538 2.7152226198791e-05 -9.64160365437504 12.8765138482124 -0.748774378533642 0.455157976493022 KLHL31 other 0.037109604807475 1 0.264299769819032 4.32898365424538 -0.748774378533642 0.449778474575867 -4.2673720461291 3.86724957107357 -1.10346435307625 0.271641008068468 -12.3458360710213 11.8982619930996 -1.0376167610178 0.301163942921154 COL21A1 other 1 1 1 -1.10346435307625 -1.0376167610178 0.212636166221118 -176.476253389889 102.69750528226 -1.71840837715436 0.0877449698863443 -338.984623809193 299.212301572638 -1.13292341934979 0.259018658832727 CDKN1A other 1 1 1 -1.71840837715436 -1.13292341934979 1.7521282857653e-08 1387.6791252691 245.311403615029 5.65680642978508 7.30886114588974e-08 -252.286687531703 724.644875238727 -0.348152172398363 0.728201353500229 SOX4 other 0.000184218767965364 1 0.000854844399623264 5.65680642978508 -0.348152172398363 3.17862968131657e-10 809.278512565359 153.263868255999 5.2802954915219 4.26400095216999e-07 -1136.64497882219 509.098419978856 -2.23266255446127 0.0269948966373694 GLO1 other 3.68053530799646e-06 1 0.00477269626576387 5.2802954915219 -2.23266255446127 0.130899178745525 31.7200505118893 16.3842352802369 1.93601043743255 0.0547220592888168 66.5437534219157 47.55176019259 1.39939621903387 0.163731657919536 CPNE5 other 1 1 1 1.93601043743255 1.39939621903387 9.44817227788993e-06 290.291796340096 68.2116987394903 4.25574793920263 3.63045834571631e-05 -96.4562803435825 183.50032891667 -0.525646362123877 0.59989994082927 RREB1 other 0.0782497628054844 1 0.34834247827148 4.25574793920263 -0.525646362123877 7.32979851423054e-16 1120.99593655145 157.843216747791 7.1019582573677 4.33980185272156e-11 -1059.78253583291 427.62663355083 -2.4782893596522 0.0142875617548404 SSR1 other 9.97365683831349e-12 1 5.71074525799631e-07 7.1019582573677 -2.4782893596522 9.16074021065977e-15 177.856532958127 22.7084627365532 7.83216966385998 7.26895343976562e-13 -32.4161602573693 61.7257903911804 -0.525163955810617 0.600224482326426 RIOK1 essential 1.2232336403294e-10 1 9.89086494548908e-09 7.83216966385998 -0.525163955810617 0.692511923559471 5.10658855790889 25.3602403365764 0.20136199381927 0.840686527997322 55.8488683164693 66.6787001209973 0.837581839704796 0.403589343763336 NRN1 other 1 1 1 0.20136199381927 0.837581839704796 5.9143274977381e-08 95.2389158097565 21.7634354734943 4.37609751115572 2.21037465481262e-05 -102.145450187916 60.0519843325291 -1.70095045689582 0.090957598786852 SLC35B3 other 0.000598707372596028 1 0.216926168623311 4.37609751115572 -1.70095045689582 7.2535964249244e-09 56.2141673193569 10.1846790237337 5.51948345042185 1.44574334261778e-07 -16.7937170022924 26.3419706006122 -0.637526981443906 0.524747142684464 RPP40 essential 7.79689079715124e-05 1 0.00166549633069568 5.51948345042185 -0.637526981443906 0.000207980106898643 139.838351532102 40.7199946337171 3.43414464540013 0.000765085294965547 -82.8017833146627 112.545746304518 -0.73571668440159 0.463029507402413 ATXN1 other 1 1 1 3.43414464540013 -0.73571668440159 3.02498053588642e-20 713.245524696723 75.3005000846203 9.47198921514731 4.6611455269023e-17 -229.710156765963 215.279819726357 -1.06703060722527 0.287627907276944 NUP153 essential 4.27943996411852e-16 1 6.59085977503986e-13 9.47198921514731 -1.06703060722527 4.04778145221907e-11 1094.69834379017 188.98198096819 5.79260698920514 3.78023123063546e-08 -1101.81223808136 555.425054418853 -1.9837280103149 0.0490637612027626 DEK other 4.86826675258387e-07 1 0.000448713447076429 5.79260698920514 -1.9837280103149 3.07997137826305e-07 89.5983808755189 23.3393615172769 3.83893881626513 0.000179196059598417 -133.217953971843 63.7984591600911 -2.08810613493903 0.0384130865197926 EEF1E1 other 0.00293428873207121 1 1 3.83893881626513 -2.08810613493903 0.075133148421605 -25.0729258389589 25.654660797895 -0.977324394833402 0.330070645074493 -173.320280142191 75.4869734382469 -2.29602900007613 0.0231380613621237 RUNX2 other 1 1 1 -0.977324394833402 -2.29602900007613 0.000252771541952571 89.7062822953499 111.938855727848 0.80138645077317 0.424150769569324 -787.876702021574 245.310785534079 -3.21174913001174 0.00160841700665182 LRRFIP1 other 1 1 1 0.80138645077317 -3.21174913001174 0.000221912466300433 -31.8272238842824 30.2615383704466 -1.05173846400898 0.294567077653843 -273.356235959143 66.9327688771218 -4.08404195052775 7.09405944626806e-05 RAB17 other 1 1 1 -1.05173846400898 -4.08404195052775 0.790382992396497 -7.63636783500999 14.6905310939858 -0.519815640847475 0.603953273155694 -20.7475969747354 31.7747077086264 -0.652959491082989 0.514775314672029 CXCL6 other 1 1 1 -0.519815640847475 -0.652959491082989 0.288359837136774 -0.158872252186088 3.00943380032664 -0.0527914095232281 0.95796742357676 -18.4058930298219 12.1967610528539 -1.5090803984813 0.133354085774865 EREG other 1 1 1 -0.0527914095232281 -1.5090803984813 0.0118032791658622 99.1823129575054 63.5671757220742 1.56027559555495 0.120788180455314 -211.861750166365 131.903554951179 -1.60618681008849 0.110322090021565 EMC3 essential 1 1 1 1.56027559555495 -1.60618681008849 0.103912917247485 7.59994108459445 6.17081004947773 1.23159536975825 0.220027604171266 -11.6545289628557 11.8912136103502 -0.980095837544415 0.32861693087079 SSUH2 other 1 1 1 1.23159536975825 -0.980095837544415 0.894270075594045 6.64859856381766 46.9651718363197 0.141564446671013 0.887614001170596 -25.0333657632613 89.2548114369309 -0.280470770821697 0.779502797768548 SH3TC1 other 1 1 1 0.141564446671013 -0.280470770821697 5.52550447079654e-12 1802.09575408308 336.455697930001 5.35611602112918 3.23607723108031e-07 -133.673361825087 531.652883015483 -0.251429769489644 0.801835399677479 CNOT1 essential 6.85107299334063e-08 1 0.00364544100081197 5.35611602112918 -0.251429769489644 3.59960787581644e-12 25.4191707745291 5.63568883027179 4.51039288010216 1.37098528788366e-05 -13.6528012244806 8.88762095865769 -1.53615925881504 0.126788938559713 LRRC29 other 4.49231062901892e-08 1 0.137235627317154 4.51039288010216 -1.53615925881504 2.83329994670707e-15 212.899879227053 47.1909558705047 4.51145511464666 1.27017719633318e-05 -185.32846215781 73.5755163109506 -2.51888768778137 0.012793168743149 BBS2 other 3.81645502821442e-11 1 0.127716317091301 4.51145511464666 -2.51888768778137 0.598934134071012 -259.492825607061 832.971226721038 -0.311526757807164 0.755824287229986 -1180.43138337012 1302.72170790351 -0.906127054004349 0.366293392847372 MT1G other 1 1 1 -0.311526757807164 -0.906127054004349 0.0660817900855656 -1159.34698067634 849.478369454442 -1.36477516363471 0.174314462672323 -3075.79400161032 1324.42347213949 -2.32236445994245 0.021522888003877 MT2A other 1 1 1 -1.36477516363471 -2.32236445994245 6.63198803667386e-19 229.410448601438 33.8204836125851 6.78318060821789 3.04612590560675e-10 -59.5342308579028 53.9419182782164 -1.10367285328718 0.271628492296605 C16orf70 other 9.30799520947176e-15 1 3.90574263616898e-06 6.78318060821789 -1.10367285328718 3.17411530219173e-11 643.104502546471 164.662511030142 3.90559149452513 0.000143235093482675 -457.223764881436 261.154151503427 -1.75078114687921 0.082083976666915 GOT2 other 3.83052234668497e-07 1 1 3.90559149452513 -1.75078114687921 2.78053441182318e-06 124.706227967097 49.4889367971402 2.51988092769662 0.0127862056239498 -120.744178961571 76.8899974428724 -1.57034962904351 0.118440839995752 DOK4 other 0.0242879680872755 1 1 2.51988092769662 -1.57034962904351 2.2488439822248e-05 13.8772762027214 5.57993542363968 2.48699584298585 0.01398540489286 -23.2492610781222 10.8039128216239 -2.15192971860983 0.0330138736539809 PIWIL1 other 0.17916540006385 1 1 2.48699584298585 -2.15192971860983 2.39451544629862e-05 22.2263286354658 12.7874497991528 1.73813614008779 0.084198705514839 -85.8507714759661 26.2669941294921 -3.26838963958858 0.00133575649921037 CLYBL other 0.190052690972722 1 1 1.73813614008779 -3.26838963958858 2.76672603900046e-09 278.886969986091 45.3458524310116 6.15022003192872 6.30364903536089e-09 9.93248396184914 89.5242183419801 0.110947452497237 0.911801548575253 TMTC4 other 3.0505921306019e-05 1 7.74151138032671e-05 6.15022003192872 0.110947452497237 6.85625393873785e-10 203.30056864338 30.6575026370707 6.63134799497826 5.30949209807761e-10 52.7539836280699 58.5145708291896 0.9015529445147 0.368702220963709 RAP2A other 7.80104573149592e-06 1 6.76057628848223e-06 6.63134799497826 0.9015529445147 0.637125101269674 118.804471837912 124.997441860125 0.950455225882596 0.343420139956709 90.3194872467378 234.385317070196 0.385346182839977 0.700530508290452 ABCC4 other 1 1 1 0.950455225882596 0.385346182839977 0.000299869947327093 580.04974789916 144.762796977223 4.00689790478713 9.57810883145364e-05 186.500762766646 286.701148913888 0.650505808829745 0.516341197619522 EFNB2 other 1 1 0.878216798755984 4.00689790478713 0.650505808829745 0.317617503599216 22.427664356391 17.453827587179 1.28497111847636 0.200796289271803 41.7940688825116 32.5917820774801 1.28234991210836 0.201711406366706 SOX21 other 1 1 1 1.28497111847636 1.28234991210836 3.17406655542542e-10 1064.69191612217 184.76946396403 5.76227204041376 4.42569398105386e-08 -488.33695487008 379.539196750094 -1.28665750218053 0.200157079362295 TM9SF2 other 3.67556907118264e-06 1 0.000523559597958671 5.76227204041376 -1.28665750218053 3.26001752041615e-09 87.4560679655479 13.4302518493074 6.51187103167077 9.52370844540587e-10 108.370767952908 53.0506416392711 2.04277958954385 0.0427467703185583 C17orf53 other 3.58047724267306e-05 1 1.20284437665476e-05 6.51187103167077 2.04277958954385 0.165000578994788 -29.4589976730143 265.015112199942 -0.111159689832287 0.911634459631015 -692.089201068688 416.014577920932 -1.66361766582186 0.098222510124754 IRF1 other 1 1 1 -0.111159689832287 -1.66361766582186 1.35165121242179e-07 163.994248368728 33.1810968067733 4.94239986471006 1.98312040207917e-06 -44.5237514340147 54.3247866852786 -0.819584468724294 0.413711493747728 ATP5S other 0.00133083578375049 1 0.0212788819143095 4.94239986471006 -0.819584468724294 0.37105632121494 66.7575246928007 56.1752211230781 1.18838027440136 0.236478138509835 -8.92837857784219 81.947057579055 -0.108953009926304 0.913378889339444 BMP4 other 1 1 1 1.18838027440136 -0.108953009926304 0.0430955532376855 -83.4751843496411 33.6415782607747 -2.48130999391819 0.0141438422887828 -31.1396736141508 51.6871316761163 -0.602464725829231 0.547734006116634 PTGER2 other 1 1 1 -2.48130999391819 -0.602464725829231 3.91033772389399e-13 390.184254958982 63.8433665430584 6.11158646679177 7.84398802030240e-09 -135.211654151656 121.10838016184 -1.11645167717518 0.265979125099069 FAM193A other 5.02517500897617e-09 1 9.59005975362171e-05 6.11158646679177 -1.11645167717518 2.20389015030735e-09 33.7493115845904 7.35701731868552 4.58736334613121 9.36612311839604e-06 -18.5261689339396 13.9144122437988 -1.3314374052843 0.185051657416712 GRK4 other 2.4423510645706e-05 1 0.0953284010990348 4.58736334613121 -1.3314374052843 0.00334388760361621 770.047840423805 224.962454293424 3.42300604268574 0.000789975640491059 -240.7399589167 900.381540877913 -0.267375493595712 0.789530978365341 SOX9 other 1 1 1 3.42300604268574 -0.267375493595712 0.250848368634021 -8.61830486093919 6.39527247738976 -1.34760557762142 0.179751744989805 -33.9195620478118 28.675203123058 -1.1828882920985 0.238664640397036 HS3ST3B1 other 1 1 1 -1.34760557762142 -1.1828882920985 6.68455196475755e-06 132.437190594059 27.8024869552638 4.76350158196856 4.4267054728811e-06 -75.3374999999999 149.050736601048 -0.505448692961844 0.613980718851005 SLC25A35 other 0.0561368674000339 1 0.0463476063010651 4.76350158196856 -0.505448692961844 3.01829623267048e-11 549.535893243315 72.8702379520514 7.54129406857309 3.66917462345151e-12 -17.7259876575761 337.517206723057 -0.0525187673531585 0.958182966639024 MRPS7 essential 3.64700733793574e-07 1 4.93320528123056e-08 7.54129406857309 -0.0525187673531585 5.79909121192287e-10 424.303694815127 61.4966850426448 6.89961897167131 1.25126296470334e-10 303.294187457145 284.837677790741 1.06479658804115 0.288623907044304 GGA3 other 6.62488180050069e-06 1 1.62564084374259e-06 6.89961897167131 1.06479658804115 3.89776076717109e-16 162.43029934067 17.2342074435401 9.42487781192127 5.65776272232623e-17 83.3048312619174 75.0697821625121 1.10969858792953 0.268836603369129 ARMC7 essential 5.32200255149541e-12 1 7.99837916055259e-13 9.42487781192127 1.10969858792953 6.2817518175014e-15 347.36658051585 38.771156515556 8.9594072432809 9.73977690412646e-16 166.08212458463 179.578560689804 0.924843834067214 0.356484758808176 NUP85 essential 8.41189385881612e-11 1 1.3659063130347e-11 8.9594072432809 0.924843834067214 3.44264685953054e-10 141.801235560947 19.9917250808573 7.09299647666356 4.38662285678959e-11 1.19973363574063 92.5968049027935 0.0129565338350507 0.98967913266447 SLC25A19 other 3.98038829898921e-06 1 5.76972504353535e-07 7.09299647666356 0.0129565338350507 3.52249100400509e-10 199.244989187193 28.156257957482 7.07640161160861 4.80210915983585e-11 43.8276544121533 130.412934068313 0.33606831044224 0.737273858737733 MIF4GD other 4.06988610602749e-06 1 6.31141206877226e-07 7.07640161160861 0.33606831044224 1.40609838902069e-08 244.462278021549 40.8038936752145 5.9911507457447 1.38811147819991e-08 -378.455328631488 177.736018300558 -2.12931139253669 0.0347979625051048 NT5C other 0.000148638660703377 1 0.000167878202173497 5.9911507457447 -2.12931139253669 8.11729613769391e-11 91.4588414634147 17.8885932119295 5.11269054977576 9.07876285337094e-07 -31.4961890243903 24.9008595584301 -1.2648635261158 0.207782669681517 TTF1 other 9.64578300042167e-07 1 0.00994396895329719 5.11269054977576 -1.2648635261158 1.86192769922575e-12 484.835698015863 69.6860744103041 6.95742588628543 8.69496506733589e-11 78.2532177063037 96.2348985513212 0.813148025137387 0.417356822745608 GTF3C4 essential 2.34416697332521e-08 1 1.13538853849272e-06 6.95742588628543 0.813148025137387 3.13608237379833e-09 113.00962338886 21.5867710551339 5.23513327214277 5.18347846971706e-07 -8.8175520123432 29.8108444207934 -0.295783369564428 0.767783900984516 DDX31 other 3.44812256999126e-05 1 0.00577128492818298 5.23513327214277 -0.295783369564428 1.14064781927506e-09 225.982811177991 58.027774863647 3.8943904312892 0.000147808595130896 -296.934067297469 115.196624602394 -2.57762819286025 0.0109115432477631 PPP1R12C other 1.28368505581216e-05 1 1 3.8943904312892 -2.57762819286025 1.52076607687708e-09 745.10746152359 161.228815787134 4.62142860682756 7.93564077170035e-06 -523.592454698312 332.947212706051 -1.57259900283525 0.117837674278109 MBOAT7 other 1.70052062716395e-05 1 0.081276832783755 4.62142860682756 -1.57259900283525 0.38819912665846 2.19485532933687 4.45224527637459 0.492977181869035 0.622960626369811 -14.3005790538409 15.2796443549488 -0.935923554346945 0.35125691630163 SRMS other 1 1 1 0.492977181869035 -0.935923554346945 0.000199988086849493 19.7714217196407 5.14781764514277 3.84073855807539 0.000200451769764186 -0.0788245494290463 17.6876986031717 -0.00445646158935068 0.996451924837726 OPRL1 other 1 1 1 3.84073855807539 -0.00445646158935068 0.027662956399615 250.451198010432 146.315860266783 1.71171599274183 0.0896214058000496 -568.161337020468 502.140868165579 -1.13147798365044 0.260187684619595 SLC2A4RG other 1 1 1 1.71171599274183 -1.13147798365044 0.29500649300031 6.69116200515952 7.95523798273635 0.841101425209403 0.402021627549566 -22.2079211595924 27.3015522707614 -0.813430714098113 0.417637658384062 FNDC11 other 1 1 1 0.841101425209403 -0.813430714098113 0.0547036453079282 754.027931924063 919.927874825078 0.819659836992589 0.414091005978769 -5348.57261372282 3157.09712448206 -1.69414256287737 0.0929215413068042 PPDPF other 1 1 1 0.819659836992589 -1.69414256287737 0.348565102950734 -24.3337348367547 19.5518005368475 -1.24457769456553 0.215177775583847 -71.9600269779902 65.3538321774221 -1.10108351079756 0.2725783370261 IL1B other 1 1 1 -1.24457769456553 -1.10108351079756 0.22519596906945 26.9286032233723 42.7056483294578 0.630563035025916 0.529254872060074 -156.886582128686 120.624386307386 -1.3006207694097 0.195318684697509 CHCHD5 other 1 1 1 0.630563035025916 -1.3006207694097 1.23125236468688e-22 4797.18949486583 434.660209824572 11.0366428452284 3.60584253080587e-21 -3237.93742470221 1817.23627449668 -1.78179220288733 0.0767797879129923 PAX8 other 1.76056775626577e-18 1 5.17726870573107e-17 11.0366428452284 -1.78179220288733 0.00329558788713748 27.7149859525376 22.0668007221522 1.25595850080412 0.211033110675539 -156.975252555443 63.1418714064164 -2.48607222210856 0.0139838971916527 INSIG2 other 1 1 1 1.25595850080412 -2.48607222210856 1.67971886425061e-15 251.206875586943 34.7789202310278 7.22296362044129 2.15196731519962e-11 -287.622304130456 98.2349191127365 -2.92790289571445 0.00392715461938206 POLR1B essential 2.27198773578537e-11 1 2.85049590571341e-07 7.22296362044129 -2.92790289571445 1.84820022022163e-07 124.931167433798 30.3242223401565 4.1198473626926 6.17059316179077e-05 -198.037521668958 86.7696306143557 -2.28233680686193 0.0238385471675181 CCDC93 other 0.00179940773440778 1 0.577567519943616 4.1198473626926 -2.28233680686193 7.33692692626809e-10 414.325069816625 67.9526420147327 6.09726211567751 8.33330590647841e-09 -312.968756495882 232.638211947587 -1.34530244999645 0.180505182863325 PSD4 other 8.33915114439631e-06 1 0.000101766331729914 6.09726211567751 -1.34530244999645 5.6519288253245e-13 1203.22190591826 225.915132440476 5.32599075112988 3.47378508504469e-07 -592.918683446272 415.279816615799 -1.42775704410122 0.155373473930946 SLC25A23 other 7.23107773912016e-09 1 0.00390592394962425 5.32599075112988 -1.42775704410122 5.82275658681803e-07 13.3480069482538 5.06903436488235 2.63324451708734 0.00930847632002122 -21.5239074785153 9.89458742774167 -2.17532136996114 0.0311116241938272 PSPN other 0.00542098638232759 1 1 2.63324451708734 -2.17532136996114 7.43877469645091e-16 410.216971180219 67.4276367140604 6.08381060305911 8.7177154740903e-09 -220.20397485126 131.616516773952 -1.67307250069119 0.0963171906264953 GTF2F1 other 1.01182213421125e-11 1 0.000106399717361272 6.08381060305911 -1.67307250069119 1.37225072743343e-06 392.391922303333 150.774905128144 2.60250153677655 0.0101466676515557 -601.657763337411 294.307628102753 -2.04431589903389 0.0426036837760806 ALKBH7 other 0.0123667235556301 1 1 2.60250153677655 -2.04431589903389 7.43742858210515e-09 171.553761058835 79.6568139661022 2.15366084227069 0.0328026711493742 -527.334736346118 155.487466303899 -3.39149353244618 0.000880846932989152 CLPP other 7.98407958288988e-05 1 1 2.15366084227069 -3.39149353244618 0.30180142586172 -7.37218882785773 12.1604985862086 -0.606240671432557 0.545241775333895 -33.5853974505128 22.549098039534 -1.48943418453499 0.138405022239709 TNFSF9 other 1 1 1 -0.606240671432557 -1.48943418453499 0.000245379614374892 143.746806336229 34.3603363409231 4.18350987341841 4.85123689482769e-05 158.698247004474 183.351103930027 0.865542904312369 0.38811396065438 MED1 essential 1 1 0.459800232891768 4.18350987341841 0.865542904312369 7.02005200273318e-08 2724.52198839475 947.026939309579 2.87692131586144 0.004589757391374 -17733.0006160327 3633.78502395535 -4.88003569257118 2.63936257785966e-06 RPL23 essential 0.000707761642915559 0.0384502340342595 1 2.87692131586144 -4.88003569257118 1.47096053907836e-07 35.0649924076012 9.78361452167024 3.58405294177667 0.000450252610493858 -107.913358199054 30.7272898011911 -3.51197124436502 0.000580056093770034 ATG4C other 0.0014436006730515 1 1 3.58405294177667 -3.51197124436502 0.457470708324676 -20.136534674777 16.3293203425658 -1.23315203893005 0.219385934614412 -29.0547765013513 30.279304973652 -0.959558897624423 0.338771676669876 CD70 other 1 1 1 -1.23315203893005 -0.959558897624423 0.00546123847290427 12070.1977865384 6875.21467588172 1.75561031263222 0.0811303678442315 -13037.0120578456 12748.6458445973 -1.02261936026487 0.308081239214413 C3 other 1 1 1 1.75561031263222 -1.02261936026487 1.10295766263663e-09 77.9489620000608 28.5784813427128 2.72754038485453 0.00711721791633456 -271.571933604419 70.1468645951203 -3.87147643977961 0.000159085687629104 SH2D3A other 1.2423715111939e-05 1 1 2.72754038485453 -3.87147643977961 5.19689750259141e-07 39.9250773805912 59.0573232749676 0.67603939979979 0.500023086457887 -633.345633307034 144.958229565818 -4.36915955171393 2.27378855946598e-05 TRIP10 other 0.00485857947517271 0.329062680325917 1 0.67603939979979 -4.36915955171393 0.079718791755189 -33.629399618932 32.5643383947216 -1.03270636766209 0.303349965917665 -133.714629654726 60.3837460980356 -2.21441428025408 0.0282596880217125 TNFSF14 other 1 1 1 -1.03270636766209 -2.21441428025408 0.107121750900162 -203.914926371114 369.488179795718 -0.551884843742104 0.58181196218232 -2497.43055938905 1184.20659901882 -2.10894835534466 0.0365358801758581 FOSB other 1 1 1 -0.551884843742104 -2.10894835534466 2.59241760684751e-16 100.777066657633 15.0054034144236 6.71605180309671 3.23739797486281e-10 -172.362659336618 48.059797546744 -3.5864208368538 0.000447267951409975 OPA3 other 3.54772349497081e-12 1 4.14743054559675e-06 6.71605180309671 -3.5864208368538 1.91037862290289e-07 722.198511406421 154.344704567437 4.67912723945041 6.17968773983693e-06 -684.477826924379 494.340275236644 -1.38462889069015 0.168130621771978 SNRPD2 essential 0.00185822528649764 1 0.0639041509176537 4.67912723945041 -1.38462889069015 0.0011132338548919 65.4384212971477 17.6997508058289 3.69713800013487 0.000300888929307216 44.195290314463 56.6893416233175 0.77960493187814 0.436797084832037 RTN2 other 1 1 1 3.69713800013487 0.77960493187814 2.4351993378587e-14 407.059093680737 58.441326252396 6.96526105384284 8.47769135381766e-11 -406.493158083218 187.177793924127 -2.17169542156262 0.0313796483680089 VASP other 3.22493448312628e-10 1 1.10718649080859e-06 6.96526105384284 -2.17169542156262 1.61358605180204e-23 618.912850919651 60.0313114080594 10.3098339250433 2.34422368531905e-19 -370.784825750243 192.620512594773 -1.92494984441394 0.0560436727859673 SYMPK essential 2.31388239828412e-19 1 3.35036449105799e-15 10.3098339250433 -1.92494984441394 6.97975411092554e-07 258.887164877652 47.6523072480445 5.4328358862052 2.15716089055192e-07 121.048001802339 167.262586229642 0.723700407430905 0.470361978454395 GPCPD1 other 0.00644859482308411 1 0.00245808483478392 5.4328358862052 0.723700407430905 0.482306728314525 -7.15605720251842 17.1147645323786 -0.418121861330913 0.676440477672714 -72.5649856044546 59.9721279886011 -1.20997850231773 0.228141153144658 SDCBP2 other 1 1 1 -0.418121861330913 -1.20997850231773 7.98754509320595e-14 157.21509562102 21.5293835190542 7.30235008735292 1.44804822693356e-11 -116.273696919589 79.9464175812266 -1.45439533674481 0.147885121970371 PANK2 other 1.04501052454413e-09 1 1.92474570324009e-07 7.30235008735292 -1.45439533674481 0.813228291895401 1.28024221506603 3.06892406618704 0.417163210120301 0.677155466982945 -3.33226375556616 11.0661230016004 -0.301122963759235 0.763737741345721 DEFB126 other 1 1 1 0.417163210120301 -0.301122963759235 0.115496005931963 -60.4090773946276 29.3020210836442 -2.06160104868489 0.0409602416941311 -115.503975955067 107.338751360849 -1.07606968117943 0.283612372249107 FOXA2 other 1 1 1 -2.06160104868489 -1.07606968117943 0.812482266449452 1.12611479237935 2.46334633750667 0.457148381952319 0.648517887283446 4.94060472370383 8.26972017884357 0.597433119483702 0.551516834554552 FAM182A other 1 1 1 0.457148381952319 0.597433119483702 0.394474769156322 -52.3879083395049 38.2950403714565 -1.36800765402908 0.17334200370841 -66.1319119721926 140.281853086232 -0.471421716474909 0.638020025698142 CD93 other 1 1 1 -1.36800765402908 -0.471421716474909 6.07931564705978e-07 70.738901711379 13.7437949483873 5.14697010374702 8.06987791183646e-07 -12.5665924061736 50.3766834320243 -0.24945255523084 0.803347521092306 GZF1 other 0.00564950803081265 1 0.00886395389836117 5.14697010374702 -0.24945255523084 0.000862296185363813 31.5071609818638 10.362540150957 3.04048626329849 0.0027851952797349 -42.4683832367317 38.1567020153758 -1.11299931581137 0.267477402312998 NAPB other 1 1 1 3.04048626329849 -1.11299931581137 2.24203036957039e-05 279.78961379103 76.9557211810092 3.63572206844675 0.000381123988823475 -456.107941005989 288.840359592141 -1.57910044721603 0.116433638036858 CENPB other 0.178644979847369 1 1 3.63572206844675 -1.57910044721603 4.4771079571474e-09 570.427385472871 111.796866598928 5.1023557531293 9.75027125867458e-07 -859.93982698536 403.02143097945 -2.13373225561597 0.0344485201619378 PSMF1 other 4.87467514374209e-05 1 0.0106628966484865 5.1023557531293 -2.13373225561597 2.38913524467849e-07 193.364568547518 38.9446724856302 4.9651096339009 1.80319311070861e-06 -99.417950785233 123.412323194675 -0.805575555274228 0.421729726376852 DTD1 other 0.00230145398119879 1 0.0193897355194497 4.9651096339009 -0.805575555274228 2.14519136778429e-07 331.994822884085 107.107442997754 3.09964287814291 0.00231442325498091 -1333.02795026271 386.214879559622 -3.45151888446836 0.000724367588000396 RBCK1 other 0.00207675976315197 1 1 3.09964287814291 -3.45151888446836 0.123102903668222 84.9390276372543 81.3125005392394 1.0445998717782 0.297877327920494 -357.756521342229 281.54026532961 -1.2707117432151 0.205785454292619 TMX4 other 1 1 1 1.0445998717782 -1.2707117432151 8.09724999453774e-11 444.904154655972 66.7037830837745 6.66984890642872 4.40145981490516e-10 -102.209550068931 235.72248015697 -0.433601199176545 0.665188802993251 STK35 other 9.62277189350865e-07 1 5.61494228587451e-06 6.66984890642872 -0.433601199176545 0.000176259581083778 1111.03562476501 315.646874251124 3.51986892758229 0.000568996364035327 -1061.01062163178 1115.45493542433 -0.951190933794348 0.3430076421799 SNRPB essential 1 1 1 3.51986892758229 -0.951190933794348 0.000304813461789201 269.737531008768 74.4525689767905 3.62294457687356 0.000398052755842359 -137.812853422906 268.465842853504 -0.513334776439725 0.608472413682466 NRSN2 other 1 1 1 3.62294457687356 -0.513334776439725 6.70055873907177e-15 119.255420821071 14.5215763361114 8.21229170035167 8.44972133336186e-14 -19.8373901317927 53.9238852184015 -0.367877612146226 0.713472922812571 AP5S1 other 8.96936792812147e-11 1 1.16234366661726e-09 8.21229170035167 -0.367877612146226 0.00122625057411741 607.704811993711 310.509573180461 1.95712101810313 0.0521532807372289 -2211.21387982106 982.852201157531 -2.24979287548714 0.0258886041281977 RRBP1 other 1 1 1 1.95712101810313 -2.24979287548714 0.362051100369037 -6.87132066524404 5.16186450546496 -1.3311702889468 0.185139309749809 -17.7245876096603 18.5857080852731 -0.953667599229373 0.341776074479356 BMP2 other 1 1 1 -1.3311702889468 -0.953667599229373 1.66410610841799e-12 87.6555193441061 13.3217601912832 6.57987518807473 6.96007447778232e-10 -71.0614560030887 42.2155141978722 -1.68330191763175 0.0943427719963619 ZNF133 other 2.0981049814934e-08 1 8.82676645272354e-06 6.57987518807473 -1.68330191763175 2.76265166412456e-05 184.90099528549 39.0604057272946 4.73371927000454 5.00652038190301e-06 228.148245154531 124.680967363715 1.82985623209824 0.0692305852184156 FLRT3 other 0.217779830682939 1 0.0521729488998112 4.73371927000454 1.82985623209824 0.00444283322296462 43.7535562582391 18.3687037963713 2.38196209940968 0.018441471614841 -72.7350275281528 57.0807748487324 -1.27424737524859 0.204495287706746 OVOL2 other 1 1 1 2.38196209940968 -1.27424737524859 0.00397092414299302 158.421739976104 48.6805369368947 3.25431373490124 0.00140100860381987 316.461108486853 152.38534367481 2.07671617791656 0.039510868482554 PCSK2 other 1 1 1 3.25431373490124 2.07671617791656 4.27860705955899e-10 183.852502143958 29.8605875385293 6.15702895687272 6.3124176386531e-09 -107.095737661227 96.0576565910878 -1.11491099681025 0.266648240147335 MKKS other 4.92253742202262e-06 1 7.75164886026601e-05 6.15702895687272 -1.11491099681025 0.0292224960460555 6.40071715775366 2.64455785462131 2.42033546234148 0.0166856261164275 -1.59220833596479 8.23494993726157 -0.193347664296094 0.846944823068224 BFSP1 other 1 1 1 2.42033546234148 -0.193347664296094 0.000742846646836714 515.143901925325 186.625851536838 2.76030302170458 0.00648571522764199 -866.923727767247 571.5607033178 -1.51676580061387 0.131402816664339 DSTN other 1 1 1 2.76030302170458 -1.51676580061387 0.604572657268303 42.0471412819897 70.3983037404344 0.597274920671694 0.551212542557172 -124.841226752297 226.462258204675 -0.551267251956244 0.582259924578141 LAMP5 other 1 1 1 0.597274920671694 -0.551267251956244 0.000845551459713481 199.793316229196 61.6902337999953 3.23865389904246 0.00147302027576075 -136.748970462469 190.349032574598 -0.718411691474592 0.473599126772912 SNRPB2 other 1 1 1 3.23865389904246 -0.718411691474592 3.15381754330533e-09 125.10277299182 23.8525956934541 5.2448284706453 5.12715755704984e-07 -144.609391180873 75.1152572908945 -1.92516668911687 0.0560636757194464 MGME1 other 3.46699162535555e-05 1 0.00571165351855353 5.2448284706453 -1.92516668911687 0.369497454092188 25.3663383062335 22.1426021005513 1.1455897636169 0.253742039464977 -28.6729352624295 76.4023222945014 -0.375288792294905 0.707962080318768 LRRN4 other 1 1 1 1.1455897636169 -0.375288792294905 1.54346703734532e-09 246.030908614659 41.1652067039014 5.97667127932439 1.59296470815445e-08 -127.10693980062 148.436139489649 -0.856307232441084 0.393193738215965 TBC1D20 other 1.72544180104833e-05 1 0.00019214340309759 5.97667127932439 -0.856307232441084 2.46500921836637e-10 284.493260890011 47.2823231658571 6.01690530078365 1.31981090138295e-08 -259.343168286031 176.105857766657 -1.4726549790846 0.142953325766031 ITPA other 2.8675452237256e-06 1 0.00015977630772142 6.01690530078365 -1.4726549790846 0.0817051014686836 9.87172000431428 4.4251894940212 2.23080164536497 0.0271781336086834 8.07232168995854 15.9566317673903 0.505891331430955 0.613675586935076 TCF15 other 1 1 1 2.23080164536497 0.505891331430955 3.82272436834333e-11 180.62996401288 25.695356740568 7.02967333112365 6.30723133636666e-11 1.82770376917741 88.6609856533616 0.0206145212091731 0.983579841802243 MCM8 other 4.6029424119222e-07 1 8.26625738944215e-07 7.02967333112365 0.0206145212091731 0.647045104335147 4.65662010046567 5.01805092691898 0.927973862418485 0.354873274187098 7.62079712536208 17.665699356646 0.43138949506095 0.666788474679854 TMEM74B other 1 1 1 0.927973862418485 0.43138949506095 0.0702856968883099 42.658215010142 20.0484466839548 2.12775661289921 0.0349704199723775 -6.28904665314394 72.5590886255574 -0.0866748297459839 0.931044058033066 FAM110A other 1 1 1 2.12775661289921 -0.0866748297459839 6.48446681987919e-13 406.258991005419 56.4877123808584 7.19198873316537 2.82283885413378e-11 -250.03682558522 210.544497658657 -1.1875723581748 0.236879071682341 MRPS26 essential 8.27807034225777e-09 1 3.73066382962321e-07 7.19198873316537 -1.1875723581748 0.505772445773421 -4.23813472871518 4.97453924897021 -0.851965280923762 0.395600634898078 -8.31581033179466 7.44440035918899 -1.11705576413956 0.265768506123745 S1PR4 other 1 1 1 -0.851965280923762 -1.11705576413956 0.0023696296789851 247.136574464807 109.971306214655 2.24728234092643 0.0260909138283736 -212.535223361392 164.572112212068 -1.29144130499777 0.198550520476324 NCLN other 1 1 1 2.24728234092643 -1.29144130499777 2.30221556291708e-06 446.749449490779 123.81339584386 3.60824809339833 0.000417756656600204 -241.812502457629 272.478921956331 -0.887453975234031 0.376236610910747 HNRNPR other 0.0203009368338028 1 1 3.60824809339833 -0.887453975234031 3.91695179257056e-08 174.480519782959 34.8583217924067 5.00541938943734 1.53415644850084e-06 9.71518062990117 76.6913105228878 0.126679027436906 0.899362973201685 ZNF436 other 0.000401565897774333 1 0.0165688896438091 5.00541938943734 0.126679027436906 9.04585787480487e-07 58.020925925926 72.3240625290649 0.802235437239288 0.42367755114198 -447.506944444444 105.601160896233 -4.2377085691717 3.9142794956737e-05 MAX other 0.00828057829859638 0.564047675326581 1 0.802235437239288 -4.2377085691717 2.69724407574175e-09 48.5733420756837 58.5958905460825 0.828954754727781 0.408447151661902 -449.083765990474 85.7166282122038 -5.23916742126979 5.37490023224599e-07 CHURC1-FNTB other 2.97532993995072e-05 0.0078462793590327 1 0.828954754727781 -5.23916742126979 5.09438395776455e-09 152.06697745013 46.5298786635645 3.26815761867023 0.00137307256387627 -402.932594319168 103.231634961051 -3.90318911902533 0.000149220814404571 TMEM115 other 5.52944434775764e-05 1 1 3.26815761867023 -3.90318911902533 1.09909455372777e-07 423.446791538816 154.138827644766 2.74717796942577 0.00675302201451529 -2036.50675695346 523.734115242655 -3.88843632233105 0.00015152432218924 PSMB2 essential 0.00108964234056571 1 1 2.74717796942577 -3.88843632233105 5.86673452800408e-12 195.270939962629 30.2540328669661 6.45437720059604 1.50626539718416e-09 -188.277033065237 107.848149058961 -1.74576044844594 0.0829561731730726 AGO3 other 7.26888408019706e-08 1 1.89006182038668e-05 6.45437720059604 -1.74576044844594 3.31112410211801e-05 124.203290285981 48.5215912503836 2.55975303128583 0.0114503684459325 -509.537824940768 167.185971245784 -3.04773074644932 0.00271989696097563 UROD essential 0.25813523500112 1 1 2.55975303128583 -3.04773074644932 2.88081519338842e-08 56.6574498607635 10.3949089950499 5.45049984446658 2.01796904963978e-07 -63.7397541560012 44.7487429649636 -1.42439205959164 0.156410113975939 ST3GAL3 other 0.000298221988819569 1 0.00230310807635388 5.45049984446658 -1.42439205959164 1.59220975698058e-06 69.8986768802229 19.3387660782015 3.61443313381883 0.000407911179181791 -220.794452181987 76.1822665683057 -2.89823947393349 0.00430430924634911 TMEM53 other 0.014266199422546 1 1 3.61443313381883 -2.89823947393349 6.7362008669098e-10 276.409667300698 53.7391327487752 5.14354536744916 8.19619649582175e-07 -564.810424800614 185.163529698525 -3.05033299872936 0.0026978025345359 HECTD3 other 7.6691646869768e-06 1 0.00900106299171144 5.14354536744916 -3.05033299872936 4.0515558332049e-17 782.375142976377 82.9304891949325 9.43410741419073 7.79341299516815e-17 181.980680238089 163.208931721948 1.11501667413719 0.26665057431192 KLC1 other 5.59600891682261e-13 1 1.1009754538274e-12 9.43410741419073 1.11501667413719 2.44948346006208e-15 577.049523468401 63.6055357774889 9.07231605574539 6.65426696111188e-16 278.052574757427 125.177020497793 2.22127490853905 0.0278508800655734 XRCC3 essential 3.30361834258573e-11 1 9.3439216667933e-12 9.07231605574539 2.22127490853905 6.49089149965413e-07 147.440423955225 26.5346003552944 5.55653456170507 1.19208410469446e-07 71.7754831412467 48.8474497613701 1.46938035643385 0.143782867534451 TUBGCP3 essential 0.00601835459847931 1 0.00138007576800478 5.55653456170507 1.46938035643385 0.0276902171799293 -65.7473055170205 29.8636802026429 -2.20158081893744 0.0292224107009064 -125.973293220492 54.7369376950817 -2.30143114549521 0.0227440860907125 MCF2L other 1 1 1 -2.20158081893744 -2.30143114549521 0.28721768898513 -0.102230284921562 9.58477682113076 -0.010665901442398 0.99150417574794 -25.8304835704259 17.5678726841264 -1.470325066379 0.143568239891084 F10 other 1 1 1 -0.010665901442398 -1.470325066379 9.21584003761503e-15 289.800714971721 35.7860291071382 8.0981523293378 1.78434377520259e-13 -33.9687702650568 65.59197099286 -0.517880004989551 0.605304965880376 PCID2 essential 1.23022248662123e-10 1 2.44651375018028e-09 8.0981523293378 -0.517880004989551 0.382759291091441 8.21006603663213 6.2767854958945 1.30800487638173 0.193197680994423 -1.56052816306369 27.1177171690734 -0.0575464429153131 0.954198954232127 SLURP1 other 1 1 1 1.30800487638173 -0.0575464429153131 4.75386346245552e-13 119.11294166961 18.1687622491074 6.55591944219873 7.89160015189693e-10 -171.146706883983 79.7973099793044 -2.14476787410967 0.0335398439069643 LRFN3 other 6.09445295886797e-09 1 9.99313327234708e-06 6.55591944219873 -2.14476787410967 2.34773671869173e-06 46.6554564435552 10.0225756940648 4.65503657619506 6.94160678811971e-06 -22.4901245094502 43.2865371955593 -0.519563956059701 0.604113491535116 IGFLR1 other 0.0206812127549555 1 0.0714221922429637 4.65503657619506 -0.519563956059701 2.34573914776556e-16 2002.11980341214 246.028420668313 8.13775822310923 1.33861371266304e-13 -1422.53335198463 1020.13750939109 -1.39445255065048 0.165215753343723 CAPNS1 other 3.21178604112061e-12 1 1.83805048885761e-09 8.13775822310923 -1.39445255065048 8.16429295456833e-20 89.9235017385968 9.16385819374394 9.81284300099565 5.8783031817214e-18 -39.0220182161635 40.5539909012923 -0.962223873629168 0.337445587401204 PDCD2L other 1.15222666467823e-15 1 8.34954183931708e-14 9.81284300099565 -0.962223873629168 3.18082336952903e-17 417.346461175069 52.9323985092398 7.88451823323701 5.25346045567257e-13 -548.993447960334 230.750951457899 -2.37916006192719 0.0185691164848865 RBM42 essential 4.39876063772169e-13 1 7.16466936944626e-09 7.88451823323701 -2.37916006192719 0.494498077693306 15.7673605950577 20.3517474601289 0.774742347110369 0.43967982398863 -47.7469503240242 89.3849937838339 -0.534171881686249 0.593992894173882 KIRREL2 other 1 1 1 0.774742347110369 -0.534171881686249 6.32667787514677e-28 868.97139096641 64.8189515625996 13.4061315405139 1.19601704235544e-27 362.18812209046 286.851576740409 1.26263249519534 0.208629854337335 UBA2 essential 9.15280488197483e-24 1 1.7329090926688e-23 13.4061315405139 1.26263249519534 0.869647960022265 -3.2272461399488 11.4170001401049 -0.28267023739558 0.777809206783663 15.2114462162254 50.1435313381607 0.30335809645399 0.762026409716623 HCST other 1 1 1 -0.28267023739558 0.30335809645399 8.86639899769314e-05 1006.29789277126 268.65652678825 3.74566702250419 0.000253239680021773 -853.564844764115 1171.16833768532 -0.728814823026284 0.467214701697908 COX6B1 other 0.654517574009708 1 1 3.74566702250419 -0.728814823026284 2.12734525533146e-09 355.009947688877 64.5330204580427 5.50121387731562 1.57619537414516e-07 -1047.89535631592 341.126255868975 -3.07186954474243 0.00252393509339128 THRA other 2.36135323341792e-05 1 0.00181230944119211 5.50121387731562 -3.07186954474243 0.706116554668458 2.14489526491814 6.10767907935482 0.351180086093311 0.725936363844397 20.3206917796162 25.0915447782555 0.80986212523775 0.419277191091007 CCR7 other 1 1 1 0.351180086093311 0.80986212523775 1.07306565678405e-07 46.4518480404768 27.494706118277 1.68948334419905 0.0931905231824095 -788.105308292599 145.339023150849 -5.4225306542388 2.28205113978451e-07 NR1D1 other 0.00106523227748952 0.00333407671522517 1 1.68948334419905 -5.4225306542388 0.00118321034915133 256.938853484394 80.6432256009535 3.18611825816347 0.00177319842866555 -256.777379477192 252.879298028224 -1.01541479069012 0.311635145368025 FRMD8 other 1 1 1 3.18611825816347 -1.01541479069012 0.699512131175835 -132.150975196764 364.058412701311 -0.362993878416941 0.717138067927775 -912.457213633941 1092.37653475642 -0.835295509013661 0.404925563602054 PRDX5 other 1 1 1 -0.362993878416941 -0.835295509013661 1.63967880014468e-10 181.65432279062 39.1240970164103 4.64302914683057 7.20871266234375e-06 -117.670633397313 68.8733848516467 -1.70850661181784 0.0895185907491902 BCL2L12 other 1.92252339316964e-06 1 0.0740406877549327 4.64302914683057 -1.70850661181784 9.67313399123596e-13 341.258376449971 66.5913463496272 5.12466551822287 8.65036773049127e-07 -241.90057581574 117.226256314707 -2.06353579326402 0.0407080117920566 IRF3 other 1.2287782109067e-08 1 0.00948599325325672 5.12466551822287 -2.06353579326402 1.64254518614952e-10 874.318899691231 189.304011737063 4.61859678338794 7.99707231781276e-06 -579.5443378119 333.247513645073 -1.7390807555406 0.083980639454732 PRMT1 essential 1.9257199762417e-06 1 0.0818820234620849 4.61859678338794 -1.7390807555406 0.374559513394669 99.1047629975811 155.492739621128 0.637359424234592 0.524819111935583 -172.961996161227 273.726734014356 -0.631878346790035 0.52838539379573 RRAS other 1 1 1 0.637359424234592 -0.631878346790035 8.45537950915046e-06 44.2683534940929 17.0649671630865 2.5941071594823 0.0103811742621807 -57.0277935914965 30.107309305439 -1.89415111835299 0.0600439771644125 PRRG2 other 0.0703910344136776 1 1 2.5941071594823 -1.89415111835299 4.6714262248016e-18 882.093246682801 154.503650406946 5.70920650974564 5.52138730826875e-08 -931.853358925147 271.985558439816 -3.42611337260153 0.000781619533180174 SCAF1 other 6.51570529835327e-14 1 0.000650198569421727 5.70920650974564 -3.42611337260153 4.59693640909582e-12 600.692149146683 126.156336735347 4.76149010577903 4.33541121159167e-06 -484.807537118376 222.574577181035 -2.17818020035617 0.0308845546454117 PRR12 other 5.71629042471066e-08 1 0.0454307740862692 4.76149010577903 -2.17818020035617 0.00641043756121085 29.7380660954713 9.207486907152 3.22977012026724 0.00152853150725808 31.6319461444308 30.3148728543576 1.04344643952164 0.298454507055172 FLRT1 other 1 1 1 3.22977012026724 1.04344643952164 5.15227823671724e-06 249.470193099989 48.6168987549891 5.13134731931843 8.4436678113384e-07 141.595743918603 193.7351344323 0.730872819396029 0.465953141913059 STAT5A other 0.0437634513426762 1 0.00926608105616276 5.13134731931843 0.730872819396029 2.50849515324452e-06 31.3698278985508 10.1637863152164 3.08643126937709 0.00240017795867824 -159.070634057971 40.4092011963546 -3.93649538591525 0.000124567563186343 WNK4 other 0.0220245874454869 1 1 3.08643126937709 -3.93649538591525 1.59836554226269e-12 269.650239561944 34.7232389144028 7.76569951399596 1.06024591480527e-12 -182.12156057495 138.022144843376 -1.31950971187716 0.188957101486806 BECN1 other 2.01697747778128e-08 1 1.43896575557371e-08 7.76569951399596 -1.31950971187716 0.297949730048467 0.69548459782381 13.1396913141411 0.0529300560565924 0.957855356055738 -37.2342494589226 29.2993808001223 -1.27082035326723 0.20568437596017 PRKCG other 1 1 1 0.0529300560565924 -1.27082035326723 1.20245592024237e-08 788.772260435315 172.824569047881 4.56400536556112 1.02406733457379e-05 -435.308663540359 356.410967042481 -1.22136719628067 0.223825672981434 TRAP1 other 0.000127604622256121 1 0.103891631092511 4.56400536556112 -1.22136719628067 6.25602311282825e-12 610.26803810986 80.5332919242133 7.5778354954639 3.2082355890393e-12 21.7038726864894 244.204423119901 0.0888758377477589 0.92929757921191 GLIS2 other 7.74307980674753e-08 1 4.31924757352362e-08 7.5778354954639 0.0888758377477589 2.18264111338005e-11 267.507684431356 78.4596831299966 3.40949228647959 0.000834851886413532 -643.564932444377 173.786849742514 -3.70318544468638 0.000297973372281537 DNAJC8 essential 2.65169068864542e-07 1 1 3.40949228647959 -3.70318544468638 8.55062092054732e-16 1133.84631146292 179.525969988326 6.31577877861707 2.81539822718338e-09 -990.159509333394 395.643051756795 -2.50265865895214 0.0133841783917232 AHDC1 other 1.16168735826556e-11 1 3.49897691674351e-05 6.31577877861707 -2.50265865895214 0.0502452634058891 3889.62577804124 3415.58672185585 1.13878700638812 0.25657191232199 -7966.43367771806 7201.86554499734 -1.10616251135816 0.270392433637069 IFI6 other 1 1 1 1.13878700638812 -1.10616251135816 2.47268646586976e-22 570.616612826896 52.6176938919552 10.844576617109 1.81499299778379e-20 -329.335137137096 230.689468672479 -1.42761236146704 0.155538879576008 ZNF384 other 3.53000719867567e-18 1 2.6023369602224e-16 10.844576617109 -1.42761236146704 1.49830006977415e-12 267.218927911473 36.9105429416014 7.23963687920436 2.48310717213522e-11 -217.739482861751 159.875993211148 -1.36192731934545 0.175347589644941 EMG1 other 1.89220315811778e-08 1 3.28614403160375e-07 7.23963687920436 -1.36192731934545 3.94304097804301e-10 273.443498222749 44.936622677138 6.08509233520717 8.47207942187567e-09 -3.24965442338056 63.2491003664251 -0.0513786663297048 0.959088681994444 PCNX4 other 4.54553763948798e-06 1 0.000103427145582258 6.08509233520717 -0.0513786663297048 7.04806422057878e-11 160.616882516188 24.7994624070082 6.47662759297553 1.12986705140138e-09 -1.98999383287084 38.5447377084676 -0.0516281586327587 0.958890195758337 ATG14 other 8.39847332524168e-07 1 1.42284157782976e-05 6.47662759297553 -0.0516281586327587 4.49038069028313e-07 847.777705827936 170.140048832731 4.98282274893084 1.6295623373114e-06 -6.59777983348715 264.441359588111 -0.0249498786565147 0.980126425462372 KTN1 other 0.00422410111534934 1 0.0175683115585542 4.98282274893084 -0.0249498786565147 0.739927432206057 -25.8063226240062 123.086044206381 -0.209660833528262 0.834202493800116 -129.156012319683 171.33869875114 -0.753805259763734 0.452088050720945 SIX1 other 1 1 1 -0.209660833528262 -0.753805259763734 0.444534322096114 -17.720390279158 15.4747034439541 -1.14511986244759 0.253913277191679 -23.7235927613932 22.0557145302548 -1.07562113795273 0.283757458148981 RHOJ other 1 1 1 -1.14511986244759 -1.07562113795273 0.0019330124076619 94.8394117062504 54.4341527583917 1.74227772272307 0.0834825132909819 -166.063516512637 84.984894210756 -1.95403569134077 0.0525325423599257 DLGAP5 other 1 1 1 1.74227772272307 -1.95403569134077 0.0173957778933579 11.6721891100112 11.1970817158437 1.04243135901163 0.298814253550949 -28.6880114152944 15.7450843877345 -1.82202970202195 0.0703535116593789 L3HYPDH other 1 1 1 1.04243135901163 -1.82202970202195 0.0233910997855605 192.379845648896 82.422191410153 2.33407826651401 0.0208670107085791 -6.3333261959458 119.111504869276 -0.0531714060946216 0.957663367029812 HSPA2 other 1 1 1 2.33407826651401 -0.0531714060946216 4.46170461742187e-08 192.459948549632 37.1607992362541 5.17911219632402 6.79164331856366e-07 -5.77777539864856 53.7025119503197 -0.10758855012208 0.914460325935636 ZBTB1 other 0.000455495424392599 1 0.00749729505936243 5.17911219632402 -0.10758855012208 4.03349535362715e-13 132.851408470245 25.2317707036511 5.2652431741947 4.510218338678e-07 -103.988358577995 35.1232244680961 -2.96067232302241 0.00354321312717504 TRMT5 essential 5.1818314808048e-09 1 0.00504016899347266 5.2652431741947 -2.96067232302241 0.00862751299724481 -36.3205942898057 23.2204929809454 -1.56416120534608 0.119806027017647 -104.308959097825 33.3283952340161 -3.12973242082066 0.0020888730660143 SGPP1 other 1 1 1 -1.56416120534608 -3.12973242082066 1.91519994951421e-07 607.421663793885 118.465644239396 5.12740776191962 8.70495913472706e-07 50.5427491733584 171.828141832608 0.294147097409667 0.769041594390718 PLEKHG3 other 0.00186214891091267 1 0.00954498769122822 5.12740776191962 0.294147097409667 9.4390944059337e-14 191.39349112426 22.9637079328564 8.33460744596979 4.29464426408153e-14 -68.4763313609468 89.4402793455739 -0.765609542613033 0.445095868797411 RHOT1 other 1.2323681656387e-09 1 5.92617962000611e-10 8.33460744596979 -0.765609542613033 0.614805491093363 -18.5915280815417 18.8248776242456 -0.987604193378483 0.324958371666748 -8.71518177691619 72.2594024537535 -0.120609657442074 0.904163802846396 EVI2A other 1 1 1 -0.987604193378483 -0.120609657442074 9.51283857777437e-06 124.723515658445 32.3089524614199 3.86033919878328 0.00016825688777864 -143.30305924194 90.844954724351 -1.57744653708906 0.116813558262804 WDR60 other 0.0787472777468162 1 1 3.86033919878328 -1.57744653708906 0.0989762614853728 712.956157635469 373.896553280424 1.90682730659127 0.0583694738436973 154.876330049263 522.034442672958 0.296678374814225 0.76710418657779 AIF1L other 1 1 1 1.90682730659127 0.296678374814225 0.601235564512698 -10.0325123152709 15.0114009525601 -0.668326184010153 0.504906778664158 4.53567733990153 20.9589210204157 0.216407959908023 0.828950693859862 FAM78A other 1 1 1 -0.668326184010153 0.216407959908023 2.91501794071164e-11 826.593596059112 125.073610809454 6.60885690202391 5.71690310710863e-10 170.627216748768 174.627800494962 0.977090796912892 0.330027355989393 NUP214 essential 3.52571419929073e-07 1 7.27247244255289e-06 6.60885690202391 0.977090796912892 1.46766887274076e-07 807.606804422217 216.035087463997 3.73831313192033 0.000261777205483465 -429.873683864174 314.908579860846 -1.36507453704224 0.174246705030678 MAP2K2 other 0.00144066376548233 1 1 3.73831313192033 -1.36507453704224 0.000211403109188098 2578.19287138585 788.738472043734 3.26875505984307 0.00133239558880069 -1122.83334995015 1289.0975927962 -0.87102276524665 0.385097515491991 CANX other 1 1 1 3.26875505984307 -0.87102276524665 4.93041842228458e-08 62.77060680463 18.4832844359544 3.39607427576705 0.000868514482076475 -69.3113235122178 27.7847278703428 -2.494583493337 0.0136590188794861 IPPK other 0.000501620770283233 1 1 3.39607427576705 -2.494583493337 1.33038027263001e-05 24.4732888146911 6.94562205613824 3.52355607847431 0.000560767616129586 -10.2762938230384 10.233668813215 -1.00416517385909 0.316874203593254 ZNF484 other 0.108532422641157 1 1 3.52355607847431 -1.00416517385909 0.281857052772062 -24.8130480533147 17.0990996116459 -1.45113185003115 0.148764009101939 -34.4882949098137 25.7039722124979 -1.34174961849067 0.18163954364678 OMD other 1 1 1 -1.45113185003115 -1.34174961849067 0.0312730084317026 33.5891281387345 15.7658366535557 2.1305008339763 0.0347185843643657 -4.75665224353516 23.22935938231 -0.204768980721763 0.838023013424426 FGD3 other 1 1 1 2.1305008339763 -0.204768980721763 0.0817997713751736 9.74896351575455 8.44206706946658 1.15480763603677 0.249993443844807 -93.0434656554059 56.6627004354917 -1.64205844303754 0.102658901525587 HIVEP3 other 1 1 1 1.15480763603677 -1.64205844303754 2.61638357198295e-06 248.840180678905 59.666394661316 4.17052483380963 5.08949876526828e-05 -494.673140994074 266.810959091244 -1.8540210742427 0.0656741163697014 PPCS other 0.0229142873234267 1 0.481212108256116 4.17052483380963 -1.8540210742427 1.59072834094925e-06 127.646951818793 23.6943618341886 5.38722894130076 2.67049978760815e-07 120.899689060803 159.107082361594 0.759863654504333 0.448513027719666 EDN2 other 0.0142545166632463 1 0.00302487510942375 5.38722894130076 0.759863654504333 0.0979414430305816 16.9490193197678 8.03883313873905 2.10839297535493 0.0366262977009613 5.78116506280756 13.1232566038154 0.440528234518159 0.660176337595002 BCL11B og 1 1 1 2.10839297535493 0.440528234518159 0.000116900326296329 127.332542272323 32.8746487460388 3.87327460913679 0.000173466868249369 1.49568115587967 51.270775959983 0.0291721965949385 0.97677453623523 TRAF2 other 0.850566774132087 1 1 3.87327460913679 0.0291721965949385 4.42367450674273e-28 233.89376523573 17.0286017467328 13.7353476647374 1.36391259195515e-28 115.041490338903 171.567080563609 0.670533589316694 0.503515567318994 ABHD8 other 6.40017227635539e-24 1 1.97753686707577e-24 13.7353476647374 0.670533589316694 0.952582067570891 0.822662779804367 4.97542752736139 0.165345143765093 0.868893485960253 -4.80497956257098 20.3834438221741 -0.235729526594711 0.813961974585566 MASP1 other 1 1 1 0.165345143765093 -0.235729526594711 0.60667350463599 -3.18986607480642 3.28148671368885 -0.972079533797827 0.332545275607328 0.728632209173976 12.524179147191 0.0581780411003942 0.953682725700344 ATP13A4 other 1 1 1 -0.972079533797827 0.0581780411003942 0.000126897841085586 20.8062176165803 5.0181591662233 4.14618526981464 5.58284563014398e-05 -10.8495416500598 18.8988377648768 -0.574085125500336 0.566753217396637 HRASLS other 0.918486573777474 1 0.524899146146137 4.14618526981464 -0.574085125500336 2.3212233257374e-59 231.975700067155 8.51983066132321 27.227736006566 3.96987182141114e-60 89.3940522682436 53.5022535715228 1.6708464840409 0.0968233600660896 HELB other 3.39014666723948e-55 1 5.79839478235311e-56 27.227736006566 1.6708464840409 1.74799947070337e-26 373.23146316817 28.8272277969174 12.9471854108733 2.59938924995025e-26 -307.215346357692 240.49856623563 -1.27741030296495 0.203405122015387 RAP1B other 2.52446083558981e-22 1 3.76053642790303e-22 12.9471854108733 -1.27741030296495 0.251701574536033 12.6138953811958 15.7897338668598 0.798866876893372 0.425597938900395 -63.4625479451812 55.12630056063 -1.15122087460563 0.251425628589763 TSPAN8 other 1 1 1 0.798866876893372 -1.15122087460563 1.01130959457457e-43 329.004937789553 16.6712266159518 19.7348968596435 5.12324212203608e-44 -52.638092105126 138.90448333144 -0.378951714463574 0.70524568033021 RAB3IP other 1.47428712697081e-39 1 7.47019933814082e-40 19.7348968596435 -0.378951714463574 0.659701906029747 2.28886132325029 3.56805384598965 0.641487326718143 0.522147504937259 14.9790019578246 19.2701199328809 0.777317526304841 0.438148627034401 PTPRB other 1 1 1 0.641487326718143 0.777317526304841 9.06806319808646e-67 1213.04851214759 39.2431599532815 30.9110814111734 1.95908095378732e-67 429.977672107396 244.136615242668 1.76121747112782 0.0802123628446764 DYRK2 other 1.32502539450439e-62 1 2.86280499776941e-63 30.9110814111734 1.76121747112782 2.56665023974706e-19 217.169469485199 20.7235650916652 10.4793489211247 1.11546407353062e-19 -86.0545616065019 172.891674737076 -0.497736873318909 0.619388832891215 YEATS4 essential 3.61230354742001e-15 1 1.59589445000026e-15 10.4793489211247 -0.497736873318909 0.00012216984050286 7.15988399509572 1.70328303719203 4.20357852380144 4.42446336064631e-05 -0.792935961520326 6.08098029638433 -0.130396074789421 0.896422149395402 TAS2R5 other 0.886586532529255 1 0.420766465597464 4.20357852380144 -0.130396074789421 0.00154526386984528 18.3204468083463 5.14654407504394 3.55975709936768 0.000494858280799176 2.44724836152263 16.3903244647005 0.149310550062215 0.881505221136465 CRYGN other 1 1 1 3.55975709936768 0.149310550062215 6.43658667724699e-09 438.607982115183 67.008184989589 6.54558815737703 1.03968741081113e-09 264.219620178618 207.148781273714 1.27550651543295 0.204242414186514 LRRC61 other 6.94314604874633e-05 1 1.31135773125608e-05 6.54558815737703 1.27550651543295 0.000317575206713897 152.992332043616 77.9045900388345 1.96384233544328 0.0516823310895463 -260.87572986282 141.2880150661 -1.84641089154499 0.0671068694220295 IDUA other 1 1 1 1.96384233544328 -1.84641089154499 1.27004882623512e-07 3484.12617404478 633.352641180133 5.50108414729709 1.86778164590543e-07 1372.36394209729 1141.13890426598 1.20262654876362 0.231257494046336 FGFRL1 other 0.00125290316708094 1 0.00213692898108041 5.50108414729709 1.20262654876362 2.33709255922297e-05 112.625149489975 42.458001529279 2.65262483945009 0.00898198477405824 -134.967674991206 77.0019681350606 -1.75278214648325 0.0819968409873594 TMEM175 other 0.185798858458226 1 1 2.65262483945009 -1.75278214648325 1.11395988087236e-11 72.0974944796697 13.5170160173926 5.3338321406811 3.34935942313665e-07 -40.2693789174541 28.8133383179784 -1.39759504688589 0.164231838684829 AUNIP other 1.36794273371126e-07 1 0.00377037390262492 5.3338321406811 -1.39759504688589 1.03411723445017e-15 306.208192113352 43.0697038989854 7.10959594316053 4.32932496530801e-11 -272.264656204039 143.153159072071 -1.90191161668298 0.0590870116473499 PIN1 other 1.40319367542544e-11 1 5.69739165434534e-07 7.10959594316053 -1.90191161668298 1.18262563089537e-18 173.474955662105 20.3219526056813 8.53633304968967 1.37397487483137e-14 -82.3525798839009 67.545198844163 -1.21922181432763 0.224661137773113 FBXL12 other 1.6570950340106e-14 1 1.90817630616581e-10 8.53633304968967 -1.21922181432763 5.18091303379552e-16 555.302177846956 77.0699852945552 7.20516781889391 2.42092932640407e-11 -146.704613424784 173.482391064008 -0.845645558174581 0.39906250123859 EMC1 essential 7.06262064767006e-12 1 3.20458414936107e-07 7.20516781889391 -0.845645558174581 0.0962565351551424 -5.07063862857419 2.33962222893281 -2.16728947343225 0.0317394995920002 -7.73315847472291 5.16437560468823 -1.497404345978 0.136321714698328 PLA2G5 other 1 1 1 -2.16728947343225 -1.497404345978 4.25718971286894e-11 1056.19297918898 173.056027397356 6.10318516536751 7.99596395231342e-09 -110.445313510353 391.123063694983 -0.282379955983581 0.778028895924206 UBR4 other 5.11458772104075e-07 1 9.77026835333176e-05 6.10318516536751 -0.282379955983581 2.83634801806742e-15 909.08590880691 184.411279303862 4.92966543173844 2.12154019763552e-06 -1203.08648235874 398.647265565454 -3.01792232451976 0.00298217617970968 HP1BP3 other 3.82027714553501e-11 1 0.0227195739764788 4.92966543173844 -3.01792232451976 0.127707392043877 2.0328331290897 4.08194938442773 0.49800547180834 0.619199949478949 61.8530093181346 30.3033541302555 2.04112749540089 0.0429680109957765 ADGRE2 other 1 1 1 0.49800547180834 2.04112749540089 8.35521976474266e-35 759.991909279907 48.1119785557587 15.796313768288 4.98132281820389e-34 28.7951075088924 314.088398437295 0.0916783544128297 0.927072741362888 SIN3B other 1.21484895379358e-30 1 7.2438396422321e-30 15.796313768288 0.0916783544128297 1.30033395297263e-24 510.427117705147 44.3518343535932 11.5085909104861 1.79293330396164e-22 -379.315987860981 260.002246639883 -1.45889503942 0.146643917809681 SLC35E1 other 1.87053039135113e-20 1 2.58146537104397e-18 11.5085909104861 -1.45889503942 3.01045698792754e-32 309.437143096199 20.9533621658521 14.7678993302799 4.15177205007313e-31 -24.0537724600999 121.355227416912 -0.198209611337664 0.84314766747583 EPS15L1 other 4.37118354647079e-28 1 6.0296185483212e-27 14.7678993302799 -0.198209611337664 0.28246553495847 -14.8259692741831 16.0780868611226 -0.9221227253121 0.357945361110004 94.0249377740778 97.79388005107 0.961460346240236 0.337868070136 KLF2 other 1 1 1 -0.9221227253121 0.961460346240236 2.23084168068259e-10 23.5540137234598 3.36150999538776 7.00697417404013 7.13300057418294e-11 12.9648849744449 21.9448736567481 0.590793329560055 0.555524963979288 F2RL3 other 2.60004597883556e-06 1 9.33139135114612e-07 7.00697417404013 0.590793329560055 0.00572900464667072 77.1953777586751 185.625708518622 0.415865767596146 0.678144993123052 -757.201446377516 279.008673045928 -2.71389931399327 0.00748567377710008 UQCR11 other 1 1 1 0.415865767596146 -2.71389931399327 2.51960802681972e-06 96.3970518034791 26.515254524267 3.63553182999831 0.000390613303467276 -73.3725089585203 55.9483656538129 -1.3114325700329 0.191889407868846 GFER other 0.0221145996513967 1 1 3.63553182999831 -1.3114325700329 0.171547436251629 14.3377441713926 30.3045733617307 0.473121465867544 0.636874027862483 -82.1407267380801 63.9439968367334 -1.28457292007892 0.201093710873078 SYNGR3 other 1 1 1 0.473121465867544 -1.28457292007892 0.000185569821248436 269.450819617445 87.5626602212772 3.07723427927525 0.00248712467955538 -177.518594007485 187.639964992994 -0.946059620156681 0.345649875176599 PKMYT1 essential 1 1 1 3.07723427927525 -0.946059620156681 0.00222438559659876 18.7411755185442 7.02394154125402 2.66818500815686 0.00858970522254506 -6.58723326775137 15.0786327114684 -0.436858791761755 0.662932999350507 WFIKKN1 other 1 1 1 2.66818500815686 -0.436858791761755 6.70258741053097e-08 140.089822528069 31.3347758200775 4.47074596392383 1.67075504121437e-05 -63.7630236629241 67.0216695584702 -0.951379219332887 0.343163922400846 WDR24 essential 0.000676626199093102 1 0.166022928445472 4.47074596392383 -0.951379219332887 0.0395980557825661 107.389955330194 54.1110396336787 1.98462191924612 0.0492759926162628 -27.4202281781962 115.737614930373 -0.236917169881996 0.813091131773812 FBXL16 other 1 1 1 1.98462191924612 -0.236917169881996 1.84045844772999e-10 232.305823508396 40.7088126867396 5.70652416949676 7.24528100130016e-08 -49.7484816005717 86.892428886655 -0.57252953149077 0.567937165651119 CHTF18 other 2.15352042968886e-06 1 0.000847552971532092 5.70652416949676 -0.57252953149077 2.35980948022136e-24 1702.05119574143 153.254255068885 11.1060615901097 2.18039094875326e-21 -485.578073097451 614.399670932604 -0.79032931830902 0.430558734585177 SMARCA4 other 3.39222612781821e-20 1 3.13169551969431e-17 11.1060615901097 -0.79032931830902 5.24969635747108e-18 540.461779806047 71.0912136888889 7.60237097894022 2.60320520406148e-12 -8.94115582078842 126.221590442742 -0.0708369763796029 0.943618817004363 KDM4B other 7.31860169195044e-14 1 3.51328574340138e-08 7.60237097894022 -0.0708369763796029 0.00126792505203773 38.9562185498225 56.0543970900191 0.694971680584876 0.488113551652656 -236.317200005607 98.5160413831833 -2.39876873540258 0.0176383394318294 TICAM1 other 1 1 1 0.694971680584876 -2.39876873540258 6.44284989979552e-12 22.2467894868541 5.21763069825366 4.26377234676654 3.55284762682812e-05 -35.1290058803553 10.9396047342169 -3.21117688744993 0.00161964568159523 METTL25 other 7.97109389602702e-08 1 0.341428656938183 4.26377234676654 -3.21117688744993 1.06636731033515e-12 214.816588442358 26.7589116443831 8.02785222722053 2.24593265295906e-13 10.4961132296859 150.829239289624 0.0695893798783351 0.944609613712732 EMC6 other 1.35268693316013e-08 1 3.07580476822743e-09 8.02785222722053 0.0695893798783351 4.34671757413875e-17 250.272133871351 27.8040773502959 9.00127455114735 9.29534464281091e-16 -255.458857504549 127.152615406418 -2.00907277202303 0.0463233966221923 METTL16 other 6.00194762637078e-13 1 1.30376503960066e-11 9.00127455114735 -2.00907277202303 0.137943664938812 -297.960688062326 156.376052621532 -1.90541123827613 0.058791713265499 -534.138039918647 390.686048335395 -1.36717971423464 0.173775859273743 TUBA4A other 1 1 1 -1.90541123827613 -1.36717971423464 0.737431282227188 -4.67989517034817 35.8361315384821 -0.13059152786407 0.896276987619773 -73.4219692998876 96.6188894159038 -0.759913198586219 0.448523478584414 VIL1 other 1 1 1 -0.13059152786407 -0.759913198586219 3.58610534542777e-07 380.269986700161 86.8961136860801 4.37614492259021 2.33535689925661e-05 -367.992433870253 222.670957378512 -1.65262878555246 0.100631477302068 AAMP essential 0.00339926925693098 1 0.228588370833884 4.37614492259021 -1.65262878555246 0.0129501124713226 359.676158892654 201.105489257825 1.78849498449809 0.0758283280021229 -766.784001153485 519.45979981693 -1.47611807771019 0.142126293759456 PNKD other 1 1 1 1.78849498449809 -1.47611807771019 0.0046962712857338 426.129377794337 143.687632460671 2.96566496710128 0.0035051398845204 97.676322652757 237.462751482708 0.411333238762164 0.681403797149264 TNFRSF19 other 1 1 1 2.96566496710128 0.411333238762164 1.61466855666647e-07 129.115255598709 34.4799753021425 3.74464466599216 0.000254186575398301 -104.479001702318 56.3166769643737 -1.85520537315105 0.0654662716117982 RNF6 other 0.00157979171584248 1 1 3.74464466599216 -1.85520537315105 0.491942727531535 150.100131853413 229.984484932342 0.652653294841041 0.515035010688361 -235.375531076244 437.949848773197 -0.537448595394171 0.591799014627366 ECHS1 other 1 1 1 0.652653294841041 -0.537448595394171 0.00174951860247623 24.1798143107225 10.6622420670049 2.26779828846212 0.0247230705406853 -23.5332716202139 21.3122852698612 -1.10421155320652 0.271212609105205 ZNF835 other 1 1 1 2.26779828846212 -1.10421155320652 8.02587162777093e-12 482.147059540942 64.5587379847198 7.46834703700466 6.04435357197439e-12 36.704061272776 201.318262340049 0.182318587723446 0.855577250143699 AKAP9 other 9.89589971704156e-08 1 8.0958071743025e-08 7.46834703700466 0.182318587723446 0.0753121712461888 -41.5916598971026 21.1353541178508 -1.96787144730046 0.050902512021926 -116.196845383157 67.947962995189 -1.7100857812527 0.0892904238082761 GNG11 other 1 1 1 -1.96787144730046 -1.7100857812527 0.000808580601318993 131.757256917718 75.5553544397463 1.74385068926903 0.0831936208519748 -646.275804186073 238.074283963299 -2.71459728210587 0.00739804788870017 SEM1 other 1 1 1 1.74385068926903 -2.71459728210587 0.057997261503597 10.2183861359329 5.99869704477931 1.70343427241853 0.0905305158252681 -21.5987273219605 19.285186448509 -1.11996466197662 0.264495365287304 GNGT1 other 1 1 1 1.70343427241853 -1.11996466197662 4.86481956012693e-06 554.261471924938 124.72301219174 4.44393911103476 1.71371808614892e-05 -650.728461124957 471.374514465003 -1.3804913951776 0.169502854174617 HIP1 og 0.0413996144566802 1 0.170086520050281 4.44393911103476 -1.3804913951776 2.03921892607121e-08 355.75437665241 62.8190679659183 5.66315910394309 7.21803167248054e-08 -257.199100680869 216.480130333152 -1.18809564778556 0.236648831557719 PTPN12 other 0.00021332269185631 1 0.000844509705680223 5.66315910394309 -1.18809564778556 0.00306955634191199 93.2342689722774 60.9331231762974 1.53010815976925 0.128082204575294 730.728520289628 215.071771402918 3.39760311417472 0.00086926338462052 FGL2 other 1 1 1 1.53010815976925 3.39760311417472 0.00112767428913739 93.7000627980788 38.3818880223253 2.44125726028842 0.0157921394182604 -302.500229128125 140.475632894088 -2.15340000892679 0.032874670499998 STYXL1 other 1 1 1 2.44125726028842 -2.15340000892679 0.998470424859481 -0.245945552751087 25.1746776190066 -0.00976956116273763 0.992217786418261 -4.19230884692744 76.5252067026893 -0.0547833717485419 0.956382055007356 STEAP4 other 1 1 1 -0.00976956116273763 -0.0547833717485419 0.00066755581903783 52.8545840080881 25.1335602662976 2.10294854561304 0.0371069931186718 -198.844317297283 81.6641662998378 -2.43490292385043 0.0160457945681347 GNAI1 other 1 1 1 2.10294854561304 -2.43490292385043 1.83794871706241e-05 24.2681388012619 5.1673686984098 4.69642098670647 6.02079453123742e-06 -3.88065194532075 20.5305404723295 -0.18901849907707 0.850339036845747 PMS2P3 other 0.147642420441623 1 0.062333285781901 4.69642098670647 -0.18901849907707 4.23241319696528e-11 125.251883672231 19.42406251882 6.44828462382031 1.44337990633786e-09 -90.6379826604302 60.894848668001 -1.48843431986487 0.138721861053198 PEX1 other 5.08566769747348e-07 1 1.81245214838845e-05 6.44828462382031 -1.48843431986487 9.79794400307041e-09 41.9094673640833 8.66417165912547 4.83710030374831 3.16790104515392e-06 -70.0369282577065 26.604187252494 -2.6325528230952 0.00933791872541798 MTERF1 other 0.000104514668680752 1 0.0334910498493672 4.83710030374831 -2.6325528230952 0.148449870966632 22.9164294057527 49.0554924734369 0.467153182045042 0.64106368083232 -265.109432033874 157.607808731313 -1.68208310341924 0.0946195879874301 SGCE other 1 1 1 0.467153182045042 -1.68208310341924 9.50416117393656e-14 59.8186977709064 8.87661216298077 6.73891082234906 3.15623446772589e-10 -77.8854922989609 27.8283677179025 -2.79878047783793 0.00579932531589475 RBM48 essential 1.24057815803394e-09 1 4.04534571728428e-06 6.73891082234906 -2.79878047783793 4.88765503523098e-07 66.472550737334 14.7815238708509 4.49700256334313 1.3655357574047e-05 -91.9360855599357 47.4907797176006 -1.93587231261784 0.0547514450537321 CASD1 other 0.00457924400250791 1 0.136717440031359 4.49700256334313 -1.93587231261784 1.59035161210764e-17 111.056040694363 12.0301670096034 9.23146292197852 1.74939517161295e-16 36.2798057223948 44.5268859408659 0.814784258000354 0.416430033484124 ZNF780B other 2.20677189696057e-13 1 2.46507273631981e-12 9.23146292197852 0.814784258000354 4.16178859038939e-08 60.9443666539373 18.3513569965121 3.3209733027111 0.00112021728123662 -206.700552652418 67.6947460158035 -3.0534209051344 0.00266624845082149 LRFN1 other 0.000425750972796834 1 1 3.3209733027111 -3.0534209051344 0.0215973722383418 -322.999220650011 394.32751670863 -0.819114078941329 0.413987131497799 -4006.2713796153 1455.11776139297 -2.75322828564757 0.00661102709787416 ZFP36 other 1 1 1 -0.819114078941329 -2.75322828564757 0.00217292322054238 -99.1217696014019 193.335964382251 -0.512691831124731 0.608926122507949 -1070.93070521244 339.594724222306 -3.15355519042571 0.00195106295450063 SRD5A3 other 1 1 1 -0.512691831124731 -3.15355519042571 0.128629906605839 23.8038963759514 17.1967725398128 1.3842072005571 0.168595982327083 58.0114749901078 28.5644657263157 2.0308965532887 0.0442434752090078 RASL11B other 1 1 1 1.3842072005571 2.0308965532887 2.56368410389342e-13 1090.29664397631 188.271189308167 5.79109659838436 3.84546324453773e-08 -446.883005992292 327.007421853695 -1.36658368014727 0.173760726146348 PAICS essential 3.31048528335758e-09 1 0.000456264213964401 5.79109659838436 -1.36658368014727 0.0170053309938812 78.9265650141754 27.5002477812918 2.87003104996998 0.0047144789436755 67.4279825300747 48.4988064048677 1.3903018966526 0.166553047420578 KDR og 1 1 1 2.87003104996998 1.3903018966526 9.94746490264935e-15 206.47477465243 33.1286886363104 6.23250672307402 4.25216104124993e-09 -79.4602777164779 57.5410773159848 -1.38093135239934 0.169313823964529 PPAT essential 1.32719076731148e-10 1 5.25184410204778e-05 6.23250672307402 -1.38093135239934 0.00161819372837572 186.762258265136 68.0190585422721 2.74573424372036 0.00679704083429666 -36.0367427121685 109.339446531161 -0.329585925806733 0.742185231681945 TUBGCP6 essential 1 1 1 2.74573424372036 -0.329585925806733 0.052636649275758 47.305161018141 24.6678002555625 1.91768866814437 0.0571869213389459 -0.266347911686072 39.5473996280717 -0.00673490328544919 0.99463595269572 ADM2 other 1 1 1 1.91768866814437 -0.00673490328544919 1.42792309529422e-09 212.104358947769 66.9026069349837 3.17034520274962 0.00187069790947186 -355.503024646548 103.096902241436 -3.44824157581396 0.00074563008368693 DGCR6L other 1.59870269749141e-05 1 1 3.17034520274962 -3.44824157581396 0.111583094888448 12.3656814404687 6.47797118956792 1.90888182095998 0.0581870885578268 3.1647522243341 10.8535364605337 0.291587192418064 0.771005120098896 ASPHD2 other 1 1 1 1.90888182095998 0.291587192418064 0.293505495200485 2.33243454814298 1.66566668987707 1.40030088991881 0.163461176249862 7.9149071496912 9.21525568104746 0.858891757715348 0.391752688343406 VPREB3 other 1 1 1 1.40030088991881 0.858891757715348 1.18147601989024e-05 127.440605462323 40.0825266095879 3.17945539470655 0.00179274565502777 -132.832401009104 74.1779825802304 -1.79072544694018 0.0753540810843468 SDF2L1 other 0.0968810336309994 1 1 3.17945539470655 -1.79072544694018 0.193885998721625 23.1767153440345 23.7601246237813 0.975445866173493 0.33087887577982 -46.7929173021281 44.7874382103411 -1.0447777138395 0.297773587938022 GAL3ST1 other 1 1 1 0.975445866173493 -1.0447777138395 1.34437456731974e-08 666.077911745988 142.279273827913 4.68148236792105 6.2018330768093e-06 -706.078106215967 325.752493159133 -2.16752940052263 0.0317308529803044 YWHAH other 0.000142302047950794 1 0.0641207521811313 4.68148236792105 -2.16752940052263 1.26029177085579e-06 64.4963060926669 12.0100265939132 5.37020510223966 3.10897404876073e-07 62.5181959139001 21.1795384037375 2.95182051289974 0.00369339289623031 RFPL1 other 0.0113942979003072 1 0.0035081663166216 5.37020510223966 2.95182051289974 2.89058751416691e-25 76.6541283473086 5.9206827460487 12.9468393486318 2.60496604119036e-26 36.7545250653681 32.5823576498312 1.12804989314696 0.261076257385561 GNAZ other 4.16620378416876e-21 1 3.76834387518597e-22 12.9468393486318 1.12804989314696 7.60299663373976e-05 248.046374786583 74.0289296817055 3.35066812195019 0.00102001970003786 -148.023166845371 128.75888147571 -1.14961519662855 0.252132056869237 MGAT3 other 0.566456526728539 1 1 3.35066812195019 -1.14961519662855 5.12707061600947e-09 9.29996167474475 1.41682553237234 6.56394274542248 7.7956037692101e-10 9.86285754938679 7.81100567597603 1.26268728490642 0.20863527743437 ADORA2A other 5.56389703249348e-05 1 9.87235261332767e-06 6.56394274542248 1.26268728490642 0.00118555798543424 386.212297369493 227.456240839289 1.6979630716854 0.0915882856327778 -875.201519051658 395.615758340135 -2.21225140960941 0.0284609104769912 ATF4 essential 1 1 1 1.6979630716854 -2.21225140960941 0.0119670755709113 -73.1059606674975 76.5262774767926 -0.955305328809018 0.340910846047512 -333.483631721329 116.35219333649 -2.86615681370866 0.00473258189456601 A4GALT other 1 1 1 -0.955305328809018 -2.86615681370866 1.0703310171156e-06 1044.13365062027 265.724609191491 3.92938258069966 0.000128282358045052 -826.190793477416 540.010630029608 -1.52995283339537 0.128079927091827 CDC42EP1 other 0.00974429357982042 1 1 3.92938258069966 -1.52995283339537 0.0632790554203143 -11.2896914391775 52.8963079294923 -0.21343061323346 0.831271579851643 -225.348145928389 105.196976277403 -2.14215421300845 0.0337429647766802 APOL3 other 1 1 1 -0.21343061323346 -2.14215421300845 0.000288352390972186 177.838562753036 70.7966842243049 2.5119617493609 0.0130717953062386 -144.794534412956 106.939594912624 -1.35398431732663 0.177791439068174 TPST2 other 1 1 1 2.5119617493609 -1.35398431732663 0.0166459435360809 -10.9114427860696 53.3758396243386 -0.204426625658065 0.838300979008961 -286.144112769486 107.746231775602 -2.65572269260818 0.00878107366084023 BAIAP2L2 other 1 1 1 -0.204426625658065 -2.65572269260818 1.71648474625503e-12 478.965782073397 71.2406244809742 6.72321144800339 3.21503139863391e-10 -79.3724035257699 141.679042958951 -0.560226847020465 0.576133525096007 MPST other 2.16345737417984e-08 1 4.12006273734935e-06 6.72321144800339 -0.560226847020465 4.08829873504461e-06 270.109412292931 71.1489410382148 3.79639399197596 0.000210235407783195 -171.946527400336 141.496708476063 -1.21519807246558 0.226138344884579 TST other 0.0351348393289734 1 1 3.79639399197596 -1.21519807246558 0.00259189500747602 92.4517438713156 131.332996094655 0.703949095965828 0.482520678161821 -682.224170597788 261.187115233549 -2.61201311553119 0.00988614584944129 APOL2 other 1 1 1 0.703949095965828 -2.61201311553119 0.0757334739509216 -6.2537278162446 59.0331395205285 -0.105935883929566 0.915770199267121 -240.137221447646 117.401535585421 -2.04543509801815 0.0425027825572662 RAC2 other 1 1 1 -0.105935883929566 -2.04543509801815 0.134763775648142 3.83668506834907 50.6941882417952 0.0756829372639187 0.939770870960862 -170.656107606029 93.9463765654606 -1.81652676606551 0.0712597821194231 LIF other 1 1 1 0.0756829372639187 -1.81652676606551 2.03755942858013e-07 52.8252218338264 9.0604325018712 5.83032011142036 3.20613248593629e-08 44.9839391140676 18.3089759103833 2.45693365561514 0.0151377875214797 C22orf23 other 0.00197724766949416 1 0.000381690072450715 5.83032011142036 2.45693365561514 2.51977899906487e-11 224.111472682342 29.507593388817 7.59504408676301 3.05992049313259e-12 204.794967363439 59.165615489106 3.46138488834191 0.000700235333285826 APOBEC3F other 3.05397214686662e-07 1 4.12232488834822e-08 7.59504408676301 3.46138488834191 0.899525498352102 10.2199224837175 24.4773680222984 0.417525384036688 0.676875684380299 15.3541455228352 38.1848371629099 0.402100589229412 0.688167528619979 RIBC2 other 1 1 1 0.417525384036688 0.402100589229412 0.0464283757715124 715.347568621989 285.891907803083 2.50216095348423 0.0133680327716074 339.997817100932 1220.02567827589 0.278680869718585 0.780856466695669 KRT17 other 1 1 1 2.50216095348423 0.278680869718585 2.108256164506e-10 300.592510254024 115.326399286753 2.60645014596022 0.0100470792122974 -721.061076069348 167.159602728867 -4.31360845741485 2.85835821700938e-05 EMC4 other 2.45990002962297e-06 0.412947011611345 1 2.60645014596022 -4.31360845741485 2.25415159479336e-08 213.790460456807 46.8219827146249 4.56602749524381 1.002647515048e-05 -634.37574197514 287.0021877399 -2.21035158989816 0.028536572314103 SPECC1 other 0.00023512791549274 1 0.101798802202824 4.56602749524381 -2.21035158989816 0.580314006954586 -1.72212055192447 8.98012278943689 -0.191770267768516 0.848174785721094 -34.5861825223917 33.114525962555 -1.0444414201037 0.297917895182002 CPA4 other 1 1 1 -0.191770267768516 -1.0444414201037 0.0360912843971762 59.9231022167824 23.0092201013088 2.60430827089936 0.0101194577678038 67.6382086716659 71.3858752996753 0.947501286322023 0.344887313069887 DOCK4 other 1 1 1 2.60430827089936 0.947501286322023 4.62595550512763e-11 156.94029031957 24.7164776750007 6.34962199643462 2.36678628145432e-09 -136.355792847404 76.2140651624351 -1.78911586144616 0.0755875142392859 POT1 other 5.5492962239511e-07 1 2.95019909983281e-05 6.34962199643462 -1.78911586144616 0.00725720252590084 355.64363159024 128.442415998449 2.76889553054292 0.00631131472505222 -430.632465363239 452.234518309547 -0.952232631363356 0.342461563268902 ATP6V1F essential 1 1 1 2.76889553054292 -0.952232631363356 0.0289408877828909 112.421858500528 48.7449549302808 2.30632808382577 0.022452491576496 -84.3029617337961 151.680471134723 -0.555793116299843 0.57917486587106 LSM8 other 1 1 1 2.30632808382577 -0.555793116299843 0.248290774396993 -59.6433233103949 44.0291299975903 -1.354633246527 0.177505703013176 -190.823490000605 138.057021552492 -1.38220778526683 0.168896469034596 CDHR3 other 1 1 1 -1.354633246527 -1.38220778526683 8.71420360136139e-10 121.918351571532 21.4523606439453 5.68321377749831 6.49306790670579e-08 -130.054869195817 66.5689837626924 -1.95368566327287 0.0525623181621289 PRKRIP1 essential 9.86796415818164e-06 1 0.000762351102926327 5.68321377749831 -1.95368566327287 0.918909116277023 11.0451215601799 105.790056270616 0.104406046745319 0.916982101265185 -123.568685407023 349.830056147993 -0.353224896590213 0.724399776895549 VGF other 1 1 1 0.104406046745319 -0.353224896590213 6.81615297742838e-05 2093.95331368737 527.213172906373 3.97173936710272 0.000109824099887026 -2358.42114489937 2031.35955841577 -1.16100625077851 0.247459432888185 PODXL other 0.510734342598709 1 0.999179660772159 3.97173936710272 -1.16100625077851 0.183541006992129 29.6134591843309 16.7466435881458 1.76832205381698 0.0790263972807292 3.3982576601287 51.968984568355 0.0653901108200212 0.947949889676953 FOXP2 other 1 1 1 1.76832205381698 0.0653901108200212 0.840131216416788 1.04820262735692 3.58973468902 0.292000027345498 0.770674561052902 7.0772163359967 12.4449412760267 0.568682180094322 0.570389607990831 STRIP2 other 1 1 1 0.292000027345498 0.568682180094322 0.00726641913229571 94.0803472478759 53.8685610722052 1.74647967896842 0.0827086401116933 -355.218630710503 174.832669224726 -2.03176347009787 0.0438856210534829 IFT22 other 1 1 1 1.74647967896842 -2.03176347009787 7.49542384779486e-12 246.477865491875 32.9567569532597 7.47882644646856 5.44601126162932e-12 -36.3614444094807 119.035976668115 -0.305466006389482 0.760426448058839 MKLN1 other 9.25459982487231e-08 1 7.30201189959259e-08 7.47882644646856 -0.305466006389482 0.0297586884498687 67.447386327948 34.9551219791265 1.92954229621125 0.0555262557449403 -126.890454339254 110.526016301029 -1.14805960248901 0.252747590290819 DNAJB9 other 1 1 1 1.92954229621125 -1.14805960248901 0.0633196028835728 312.129537284009 139.487506124302 2.23768813391688 0.0266858031724886 -141.63520043295 489.792062998022 -0.2891741437499 0.772839576464474 FLNC other 1 1 1 2.23768813391688 -0.2891741437499 0.0235319534192623 31.2851632401479 25.5491325501137 1.22450980199751 0.22260588941359 -187.809583648149 88.4298965680173 -2.12382453148853 0.0352617573052328 LRRC4 other 1 1 1 1.22450980199751 -2.12382453148853 0.00126639792781724 798.574656465593 245.367506085131 3.25460640329664 0.00139248295355209 -937.915832764169 863.627218999314 -1.08601930570337 0.279145759769494 CALU other 1 1 1 3.25460640329664 -1.08601930570337 0.227503784430904 5.69247857422344 3.31257920040738 1.71844301066775 0.0877125425714313 6.4758310508623 11.6633017793479 0.555231372159895 0.579536840488415 CCDC136 other 1 1 1 1.71844301066775 0.555231372159895 1.69601747696502e-05 457.432258986864 99.4233964608541 4.60085126107082 8.65773072266816e-06 -137.56538608168 344.682389537886 -0.399107672040087 0.690359688569914 SMO og 0.136648128119071 1 0.0884214038706099 4.60085126107082 -0.399107672040087 0.337147478380972 27.3374533293225 21.8218792787295 1.2527543104855 0.212181842822647 -40.2244350857324 78.6445474500048 -0.511471378372462 0.609748881188519 IRF5 other 1 1 1 1.2527543104855 -0.511471378372462 0.22051527534332 -59.8277970979735 36.5186822802433 -1.63827918649574 0.103418344284505 -124.902452998627 113.861833604319 -1.09696505883328 0.274380171359863 LRRC17 other 1 1 1 -1.63827918649574 -1.09696505883328 0.000544336599945968 190.7701643367 52.728268763978 3.61798649583252 0.000402034886769956 -152.216490483702 190.814587614001 -0.797719358813493 0.42626168432499 KLHDC10 other 1 1 1 3.61798649583252 -0.797719358813493 4.34205320258765e-07 245.667819017589 56.9120639748619 4.31662114953521 2.82380848067271e-05 -378.493162990987 175.918327603344 -2.1515277466962 0.0329935198610669 NDUFA5 other 0.00409021411683757 1 0.274248279642934 4.31662114953521 -2.1515277466962 6.21512243274119e-10 265.650632450448 48.8110974230668 5.4424228602758 2.02984459617356e-07 -262.715236860546 181.471114939519 -1.44769726547448 0.149734454939423 MRPS12 essential 7.0914546957577e-06 1 0.00231645865315327 5.4424228602758 -1.44769726547448 0.0487735606430708 125.894305121921 50.9942996455619 2.46879172764319 0.0146570683626329 93.340036481239 178.869885515341 0.521832035685143 0.602541905673995 MYO1B other 1 1 1 2.46879172764319 0.521832035685143 0.0148339240256376 244.481215152936 83.4607729318047 2.92929488386958 0.00396349887481152 322.554465634933 313.230707823448 1.02976642321014 0.304882868147315 HOXD3 other 1 1 1 2.92929488386958 1.02976642321014 2.64530261850603e-06 229.694814451114 47.969548882432 4.78834635310142 4.13056107184887e-06 -168.644891268195 173.612242522278 -0.97138824323725 0.332983813688687 MTX2 other 0.0231543338197833 1 0.0433337162047665 4.78834635310142 -0.97138824323725 0.0041359735921367 44.0487771239425 15.19898527092 2.89813933882944 0.0043413513422781 -52.0830728208901 55.9217606447708 -0.931356098598808 0.353228224589284 PDE11A other 1 1 1 2.89813933882944 -0.931356098598808 0.817432418448237 -13.1639550750498 32.1069333804648 -0.410003500460722 0.682376893787082 39.2240999265249 111.867947159034 0.350628584171325 0.726349292810463 CHN1 other 1 1 1 -0.410003500460722 0.350628584171325 0.261935002911691 8.12433263531232 7.88708154819163 1.03008097300263 0.304576678172487 -22.5735563227498 24.3807725126008 -0.925875351615007 0.355950083010704 GAD1 other 1 1 1 1.03008097300263 -0.925875351615007 2.30084703966011e-14 87.7342128222869 10.9594996331488 8.00531189917838 2.94374378028665e-13 -42.2831162188995 39.5266989641481 -1.06973557941814 0.286445345681531 OSGEPL1 other 3.04977275106947e-10 1 4.02615836829806e-09 8.00531189917838 -1.06973557941814 8.96946553906542e-06 112.215906014019 32.2980166370883 3.47438999969924 0.000668445383500053 -275.870588766208 116.486520688577 -2.36826189962133 0.0191379973044828 ORMDL1 other 0.0744734723708602 1 1 3.47438999969924 -2.36826189962133 0.000343909827474176 162.959467617484 45.3175471272015 3.59594633752076 0.000433966022199095 -116.970975531533 140.086900406234 -0.834988676259755 0.405009238036824 HAT1 other 1 1 1 3.59594633752076 -0.834988676259755 0.195609085091218 41.8987911827446 42.9289932045735 0.976002185354789 0.330734901158935 261.75043454215 151.300903553096 1.72999915000702 0.0858185642144258 HOXD9 other 1 1 1 0.976002185354789 1.72999915000702 0.231624978567181 61.698862289642 36.5145651055397 1.68970552192833 0.093294185891678 15.647467804377 128.693600313178 0.121586992409092 0.903399224253234 HOXD10 other 1 1 1 1.68970552192833 0.121586992409092 0.275969738546266 33.8241289405072 21.965351781317 1.53988560152617 0.125829456826994 -5.46782412894051 77.4156886358286 -0.0706294063295325 0.943792783032591 HOXD11 other 1 1 1 1.53988560152617 -0.0706294063295325 0.191592164867769 63.0370924911011 35.0652109264565 1.79771034668267 0.0743181912502154 17.3320809085259 125.125985126332 0.138517038575375 0.890025323227509 HOXD13 other 1 1 1 1.79771034668267 0.138517038575375 2.24306083747863e-15 817.017714900063 100.061450199458 8.16515964211448 1.21578492850095e-13 130.545851048233 148.084516200381 0.881563139738283 0.379423520197932 HERC2 other 3.02678629409367e-11 1 1.67024533477461e-09 8.16515964211448 0.881563139738283 0.0775932573256671 77.1701237231833 266.410666046572 0.28966604403779 0.772503369075723 -658.132302016808 383.202412480829 -1.71745344126646 0.088123420620854 SNRPN other 1 1 1 0.28966604403779 -1.71745344126646 8.87822749833124e-12 247.808005427408 50.9917793183406 4.85976384311573 3.03475602881057e-06 -356.148639917296 136.454208513848 -2.61002312641133 0.010010574923455 PSMG2 essential 1.09388641006939e-07 1 0.0321441358571616 4.85976384311573 -2.61002312641133 4.34930941388544e-12 550.327695325686 84.3896196845563 6.52127237191945 9.88518923176202e-10 -116.545404649999 225.652852543265 -0.516480972150144 0.606274087602959 TWSG1 other 5.41315049652182e-08 1 1.24780743672532e-05 6.52127237191945 -0.516480972150144 0.964144744218885 -0.144175653356626 6.30254299944628 -0.022875790513336 0.981778400053267 3.4072994591794 14.2606142081872 0.238930764792952 0.811470873949303 ARHGAP22 other 1 1 1 -0.022875790513336 0.238930764792952 1.38597063472915e-12 449.884055879467 67.8251656818183 6.63299604736633 5.2635785413122e-10 -51.8213646597002 95.9901193182071 -0.539861446446509 0.590072375237605 EIF2AK4 other 1.75269846467848e-08 1 6.70264091450695e-06 6.63299604736633 -0.539861446446509 3.14220535100389e-06 154.259775040171 85.092356307508 1.81285113885794 0.071827918898871 -455.333558448415 127.457337455636 -3.57243896301303 0.000474122218602993 MYO5C other 0.0272783642596068 1 1 1.81285113885794 -3.57243896301303 0.247347845626674 40.7807675474653 31.6891064999798 1.28690177955921 0.200059531900649 -20.0359227774908 48.4244082325651 -0.413756688182238 0.679627945771981 CGNL1 other 1 1 1 1.28690177955921 -0.413756688182238 0.0580226569340439 37.8027576536571 15.7185866219115 2.40497180585947 0.0173682128977553 22.6528038855073 23.435068928379 0.966619895795381 0.335259518743114 TMOD2 other 1 1 1 2.40497180585947 0.966619895795381 1.00900551806913e-08 97.0131070676931 16.2495517800225 5.97020203270853 1.87680638543572e-08 23.2316247968669 24.9066935014625 0.932746243314185 0.35256836614185 TTBK2 other 0.000107519628005447 1 0.000225798576231771 5.97020203270853 0.932746243314185 0.000592975638073392 14.1293700660543 12.5269964231591 1.12791363458306 0.261327829636767 -58.6777831480588 22.0404839425951 -2.66227290203275 0.00869038161486836 ELL3 other 1 1 1 1.12791363458306 -2.66227290203275 2.67691170351982e-14 281.372074089152 38.3018730472614 7.34617008786911 1.16183701717183e-11 -21.1239161408507 60.4566714651476 -0.349405874139603 0.727268223141549 INO80 essential 3.54128649258636e-10 1 1.54768309057459e-07 7.34617008786911 -0.349405874139603 1.69477130372462e-08 220.143715059282 41.1194797439973 5.35375730505003 3.24522327738335e-07 -47.1961946201269 63.2959184547479 -0.745643570270156 0.457073391282685 ICE2 other 0.000178323836577904 1 0.00365541949964461 5.35375730505003 -0.745643570270156 0.0221964641745426 41.132435989979 14.7862477274709 2.78180352095417 0.00610032536842239 27.1018390626598 23.189039814793 1.16873485401369 0.244364518124776 DLL4 other 1 1 1 2.78180352095417 1.16873485401369 0.56891501632814 -132.014521499652 209.834889734948 -0.629135229448283 0.530192671412343 -349.67549105319 334.584670699442 -1.04510314331556 0.297612974488374 ALDH1A2 other 1 1 1 -0.629135229448283 -1.04510314331556 5.17315943528224e-06 134.62447317227 42.5121572181381 3.1667288131601 0.00185894210006106 -155.380774465869 67.7862301236965 -2.29221737486108 0.0232475237593135 MINDY2 other 0.0439356430838521 1 1 3.1667288131601 -2.29221737486108 3.85392195970348e-14 516.86133177253 101.304617814062 5.1020510508336 9.88806198689127e-07 -474.675564861384 145.095165994667 -3.27147745831056 0.00132397168745884 IVD other 5.08255228045695e-10 1 0.0108106181702682 5.1020510508336 -3.27147745831056 3.76071721528831e-05 146.722674046462 42.1608105072981 3.48007242462913 0.000656580206602648 -47.2753994251793 60.6181553879213 -0.779888452933679 0.436685374754486 KNSTRN other 0.290778655086092 1 1 3.48007242462913 -0.779888452933679 1.5248420656316e-07 332.150859581696 107.377395504969 3.09330337190313 0.00236137155725108 -473.813341753132 160.890050945063 -2.94495115745174 0.00374529348126721 DUT essential 0.00149480267693866 1 1 3.09330337190313 -2.94495115745174 0.00205552613941563 103.259519768346 30.1819092747689 3.42123882317373 0.000802109841070861 37.9810313877217 47.5517502865524 0.798730460158535 0.425701217609648 CHAC1 other 1 1 1 3.42123882317373 0.798730460158535 8.62840010338019e-06 256.261022649639 68.9568130854763 3.71625385778759 0.000282436747877901 -195.101266487992 116.014797228259 -1.68169294908244 0.0946551704166792 CLN6 other 0.0717278900593995 1 1 3.71625385778759 -1.68169294908244 5.33289027699139e-12 747.472507415012 125.026807655414 5.97849790322662 1.52697100898803e-08 -380.984664067693 186.489716833613 -2.04292585423147 0.0427759837543205 ARPP19 other 6.61545038860782e-08 1 0.000184320670494946 5.97849790322662 -2.04292585423147 0.00107633474483589 172.392493542014 61.7176353599769 2.79324527805562 0.00593342422114113 -101.869422073646 96.0285597236644 -1.06082422111495 0.290558185747604 VPS13C other 1 1 1 2.79324527805562 -1.06082422111495 0.000279022829228536 109.306941285106 34.1930970954083 3.19675462506683 0.00168675967896495 -70.2059976126665 57.5273863253039 -1.22039261814656 0.224181495536609 CALML4 other 1 1 1 3.19675462506683 -1.22039261814656 0.0675893567548303 136.522354165288 418.614900662802 0.326128749715142 0.744787633497116 1653.61984293453 730.26803498921 2.26440123859312 0.0250021366638528 ISLR other 1 1 1 0.326128749715142 2.26440123859312 1.67941749228053e-06 24.294057107116 11.0119988339936 2.20614417721525 0.0288744628408615 -69.5188919741095 19.1897252988369 -3.6227142854579 0.000396830115032079 THAP10 other 0.0150139923809879 1 1 2.20614417721525 -3.6227142854579 0.0432887174319498 361.209131585394 144.843763021168 2.49378450304833 0.0137241096814863 346.386984235083 251.837710871424 1.37543731253153 0.171046490575496 LOXL1 other 1 1 1 2.49378450304833 1.37543731253153 0.184791008923731 -10.9243089200848 5.95209054668606 -1.83537344306146 0.0684442058346461 -10.8049846683336 24.0948553491145 -0.448435340730555 0.654490474009353 ACKR4 other 1 1 1 -1.83537344306146 -0.448435340730555 0.00733576024815029 143.019534060494 47.0514445716437 3.0396417232785 0.00278677549304875 -93.7624375245826 181.233019150075 -0.517358470130325 0.60565310303867 ANAPC13 essential 1 1 1 3.0396417232785 -0.517358470130325 0.000418611261751351 117.003086203268 31.0202031802075 3.77183494007293 0.000231107932153233 -116.459704005051 128.222931136392 -0.908259567714696 0.365169501952696 MBD4 other 1 1 1 3.77183494007293 -0.908259567714696 1.21653400072596e-12 535.58607380776 124.336252538019 4.30756165539083 2.93913939891036e-05 -611.333876883178 197.5438571693 -3.09467419358553 0.00234332258202074 COPB1 essential 1.5408619653195e-08 1 0.285008347512338 4.30756165539083 -3.09467419358553 1.60043956014681e-07 154.161256212329 136.55290519057 1.12894893006623 0.260686380787223 -877.903535671154 216.953519576043 -4.04650515643488 8.22620174017061e-05 PSMA1 essential 0.00156619015355967 1 1 1.12894893006623 -4.04650515643488 0.00650639447905779 420.855702002712 179.755929963558 2.34126185482744 0.020534617304657 -421.172100280459 460.066389958792 -0.915459397758185 0.361419857220561 SUMF2 other 1 1 1 2.34126185482744 -0.915459397758185 0.00611126034464806 540.808458969947 217.03601985355 2.49179126734295 0.0137489846116122 4.17282201760451 328.367859371877 0.0127077663008388 0.98987707613026 PALLD other 1 1 1 2.49179126734295 0.0127077663008388 1.88623419257096e-13 558.934304945207 130.33801620373 4.28834442340706 3.15380563312425e-05 -554.841056164358 207.387158766305 -2.67538771187653 0.0082660840801129 SPCS3 essential 2.44361639647568e-09 1 0.305130695004771 4.28834442340706 -2.67538771187653 0.0350312261387587 -64.2297484278637 62.0849779392988 -1.03454572361549 0.302502953262053 -273.562814313786 105.643283278135 -2.58949557250655 0.0105332817163395 BBOX1 other 1 1 1 -1.03454572361549 -2.58949557250655 0.216573914475865 -7.34338051623646 12.3278406283386 -0.595674517348633 0.552272816378118 20.0726836831376 19.2331119007299 1.04365241499873 0.298292414090673 MYOD1 other 1 1 1 -0.595674517348633 1.04365241499873 1.24280361682481e-11 12.0352664567745 3.05066335612144 3.94513096065634 0.000120259472455685 -99.4999855525736 17.6726844148807 -5.63015686902625 8.16618994334046e-08 SERGEF other 1.52268299133376e-07 0.00119357032211864 1 3.94513096065634 -5.63015686902625 0.00596745668505288 79.9658667496404 29.4826693950792 2.71230076483465 0.00743202292867551 -0.107816369128658 47.614165444575 -0.0022643759083452 0.998196184005189 E2F8 other 1 1 1 2.71230076483465 -0.0022643759083452 4.70871673745597e-12 235.495522445486 79.4558994720016 2.96385194819258 0.00351500254886113 -441.902888527649 125.300434043392 -3.52674667012421 0.000552690248526007 DCTD other 5.85246403298402e-08 1 1 2.96385194819258 -3.52674667012421 0.00032840478502042 37.0168589174801 21.7137607681064 1.70476497889076 0.090350781167725 -329.032608695652 105.468527526854 -3.11972316681747 0.00217910427902391 SOX15 other 1 1 1 1.70476497889076 -3.11972316681747 3.98615876902316e-05 98.5832552473765 21.2419468900881 4.64097079978 7.30391930108646e-06 127.724325337333 106.41778506011 1.20021597203125 0.231874932270306 PIMREG other 0.306734917276332 1 0.0749893394642547 4.64097079978 1.20021597203125 2.92890749090389e-24 359.440311937612 30.7485701715603 11.689659386831 4.16878872573281e-23 -368.779789496645 163.859209488847 -2.25058933609554 0.025800296247409 RPAIN essential 4.2088400644289e-20 1 6.01055958476156e-19 11.689659386831 -2.25058933609554 4.59210265865891e-06 15.3987961548828 3.25628976632821 4.72893914851026 5.01313215263799e-06 -18.8527984907016 16.6476536151422 -1.1324598004342 0.259178799397623 USP6 other 0.0391844119863365 1 0.0522368370304878 4.72893914851026 -1.1324598004342 1.33183334304605e-11 209.789383688946 31.1636353814936 6.73186491629689 3.38765182150149e-10 -336.421381309941 147.092817253223 -2.28713670451213 0.0235959222741094 PLD2 other 1.6297792806112e-07 1 4.3361943315219e-06 6.73186491629689 -2.28713670451213 0.0143172851214946 -299.066404736871 184.268302778011 -1.62299429814122 0.106733242614479 -2534.92417870252 896.282328205243 -2.82826526746162 0.00533360970970607 CD68 other 1 1 1 -1.62299429814122 -2.82826526746162 5.05860452213511e-07 258.498799076213 47.9078016535821 5.39575580915607 2.48948920980152e-07 -143.200508083135 241.658863822281 -0.592572959328512 0.554324956547224 TXNDC17 other 0.00473181867000518 1 0.00282457445744081 5.39575580915607 -0.592572959328512 9.32612524674459e-05 368.106787935863 84.6977682817359 4.34612145518881 2.59257229032627e-05 194.992342197217 431.015146654337 0.452402528567277 0.651655130354939 ATP1B2 other 0.686589340665337 1 0.252879501198424 4.34612145518881 0.452402528567277 3.67808912532726e-23 349.053985145771 30.1727707204373 11.5685095140879 2.05362909448926e-22 -66.4189335993816 160.212817671184 -0.414566915212101 0.67906331947107 FXR2 other 5.26959828985636e-19 1 2.95640444442674e-18 11.5685095140879 -0.414566915212101 3.91663709197265e-10 843.408234859676 120.560070841693 6.99575098929022 7.7196491061738e-11 166.731905465287 614.212511827075 0.271456380739161 0.7864059650342 KIF1C other 4.51666589446286e-06 1 1.00903533466798e-06 6.99575098929022 0.271456380739161 6.84245067714756e-08 232.721210779703 54.74985335729 4.25062710690741 3.77058832924233e-05 -793.311954697211 266.303674024089 -2.97897487747559 0.00338455449611297 MPDU1 other 0.000690403273324189 1 0.360958420758368 4.25062710690741 -2.97897487747559 2.44320043956961e-07 190.751469653951 34.1260331067976 5.58961743537533 1.02691006385178e-07 -103.680503773254 217.62315175854 -0.476422213976071 0.634457747579475 PHF20L1 other 0.00235084746295388 1 0.00119255065715107 5.58961743537533 -0.476422213976071 0.103094387612377 19.9278928571428 12.1357021394763 1.64208816499536 0.102652734090462 -80.2051071428572 76.5311966245198 -1.04800539754216 0.296310676339137 LRRC6 other 1 1 1 1.64208816499536 -1.04800539754216 7.39698867788242e-08 76.6563873125431 26.7653635900627 2.86401442127256 0.00479140802149208 -286.383363278957 72.9094974048041 -3.92792946697898 0.000131009991495865 CCNT1 other 0.000744358970655308 1 1 2.86401442127256 -3.92792946697898 4.29340274501812e-06 48.6743520805327 17.1021719906026 2.84609183601233 0.00507246393858226 -143.861506236909 48.5795728421845 -2.96135799102756 0.00358359883862753 PUS7L other 0.0367944615248053 1 1 2.84609183601233 -2.96135799102756 1.39977280939869e-25 349.466206812185 29.7256453577375 11.7563875437012 3.23883727800698e-23 -8.32044374383613 119.330063804731 -0.0697262992958046 0.944501384394799 KRI1 essential 2.01819243659103e-21 1 4.67007947115826e-19 11.7563875437012 -0.0697262992958046 7.48805009038297e-13 1555.2224631758 224.178299075741 6.93743537883816 1.02048825804605e-10 -971.375320421927 912.508681927374 -1.06451077086765 0.288752882674593 ILF3 essential 9.54127342516598e-09 1 1.3297982490598e-06 6.93743537883816 -1.06451077086765 2.99967558215262e-16 3027.89823022865 364.231285572604 8.31311957584457 4.42391087160685e-14 -1025.70445867038 1473.94444885944 -0.695890852239435 0.487539295752507 SLC44A2 other 4.10115645591906e-12 1 6.10366982955597e-10 8.31311957584457 -0.695890852239435 1.49612167961507e-13 699.702358328084 98.2818004791208 7.11934818976714 3.79867231957346e-11 -454.448570591562 394.54058543979 -1.15184238925634 0.251159381975276 AP1M2 other 1.94391089832386e-09 1 5.00816958612565e-07 7.11934818976714 -1.15184238925634 1.94740750486663e-06 61.7107380814668 12.6499085110303 4.87835449779398 2.63059231475666e-06 3.62628596324245 50.7815514710878 0.0714095150343537 0.943163892964476 CDKN2D other 0.0172949260507206 1 0.0279763492674371 4.87835449779398 0.0714095150343537 0.000125273732060184 95.21972445465 63.9309372879843 1.48941543005574 0.13843647896131 -222.982344686822 120.745920228652 -1.84670707105108 0.0667214217233435 MTUS1 other 0.907733462508094 1 1 1.48941543005574 -1.84670707105108 0.776768913024943 4.27977371973017 27.3665470870796 0.156387055557723 0.87592885352029 -24.3374751885667 51.1406431366508 -0.475893021594108 0.634812122642329 KLK14 other 1 1 1 0.156387055557723 -0.475893021594108 0.0503356052970976 12.6817021417678 6.47272381539984 1.95925278189618 0.0518543965968273 29.2333300179033 12.4678227138663 2.344702093445 0.0202939366807829 SIGLEC9 other 1 1 1 1.95925278189618 2.344702093445 0.22891971893174 335.029611317626 740.875929885295 0.452207445002966 0.65174371704941 -1519.1696344148 1384.49587440596 -1.097272778127 0.2742022530515 KLK10 other 1 1 1 0.452207445002966 -1.097272778127 0.249421012703595 99.8168826013227 230.772633112154 0.432533447554903 0.665947288547428 -461.239091991768 431.251368254121 -1.06953653007305 0.286469567730885 KLK8 other 1 1 1 0.432533447554903 -1.06953653007305 2.90470835160554e-17 143.056023849339 21.6410233824138 6.61040937489081 6.95476553618367e-10 -251.518423529762 49.2868396358203 -5.10315584014369 1.03829645850501e-06 NGDN other 4.01895447528143e-13 0.0151497836260467 8.82072912954174e-06 6.61040937489081 -5.10315584014369 0.0489997983535607 -37.310000326779 21.9070076841444 -1.70310801295709 0.0906756709810524 -104.75189754589 43.86340183751 -2.38813893035335 0.0182127563449754 RIPK3 other 1 1 1 -1.70310801295709 -2.38813893035335 0.185958546625646 -37.8023908335536 26.5049259935302 -1.4262401956067 0.155933802883018 20.025955159988 53.069603858729 0.377352640756412 0.706459518409584 ADCY4 other 1 1 1 -1.4262401956067 0.377352640756412 1.70459329400132e-20 144.869671224445 14.6668119818477 9.87737971985612 3.57158872971888e-18 -104.906131230105 48.528832060209 -2.16172792083579 0.0321638044367939 RAB2B other 2.41438594162347e-16 1 5.08022780915213e-14 9.87737971985612 -2.16172792083579 2.74589122532867e-05 101.123328598717 34.3867949531635 2.94076050810934 0.00381209727611749 -214.074480416647 81.1823329878374 -2.6369589606241 0.00927714756387473 BCL2L2 other 0.216568440941672 1 1 2.94076050810934 -2.6369589606241 0.003268457541777 183.977089649199 63.1384364388851 2.91386831897999 0.00412813469601371 -112.32364660026 147.773001480406 -0.760109393969055 0.448406567286532 AJUBA other 1 1 1 2.91386831897999 -0.760109393969055 1.0989436368847e-09 79.3312996319966 25.654003616275 3.09235551762644 0.00236319016728264 -175.799050939376 43.5231408124775 -4.03920874407523 8.48450488794287e-05 DTD2 other 1.23806990131431e-05 1 1 3.09235551762644 -4.03920874407523 1.08657415022455e-17 150.880192523446 17.5859396841592 8.5795922898197 9.94367757734244e-15 -135.834307930665 52.5238848770133 -2.58614358493714 0.0106380377117018 PARP2 other 1.5102294113971e-13 1 1.38336442455988e-10 8.5795922898197 -2.58614358493714 2.32917560867191e-06 130.304893795596 30.3081646970967 4.29933303774341 3.04878724221719e-05 -41.2348763638712 51.419128944172 -0.8019365012706 0.423841646123505 HEATR5A other 0.0205270246392255 1 0.295244556536312 4.29933303774341 -0.8019365012706 0.24677602745023 -29.6325428226208 34.7681380846173 -0.852290184493123 0.395420906024886 -88.2382825147879 52.6697731251429 -1.67531161193982 0.0959704936521787 FOXA1 other 1 1 1 -0.852290184493123 -1.67531161193982 9.90877710557936e-10 393.907007395733 106.458755202542 3.70009029925542 0.000303262347551805 -624.551051056357 175.439563636967 -3.55992136613339 0.000499150578065648 SNX6 other 1.11889911076202e-05 1 1 3.70009029925542 -3.55992136613339 3.67300211786016e-14 170.577404320126 45.1241489754688 3.78017997442696 0.000226707751965599 -399.032448648591 74.3627049807615 -5.36602923134421 3.04146425579754e-07 EAPP other 4.84579169409291e-10 0.00444236269201788 1 3.78017997442696 -5.36602923134421 0.337729586860897 125.002169438727 141.067790419891 0.886114180045316 0.376983905271559 -153.196594954664 233.316533205526 -0.65660411137566 0.512448314199046 EGLN3 other 1 1 1 0.886114180045316 -0.65660411137566 3.01205034142198e-07 200.315836658369 40.6548362768286 4.92723264937951 2.32067208508168e-06 -48.3025967979625 61.4399396241073 -0.786175850651551 0.433093123602441 MIS18BP1 essential 0.00287108638544343 1 0.0247662124919917 4.92723264937951 -0.786175850651551 1.73092463417089e-12 22.6005579082576 2.95875141710547 7.63854569789023 2.80580756963148e-12 -1.91363681275377 6.74699130952182 -0.283628172168107 0.77710272266987 NRL other 2.18113813151874e-08 1 3.78307034613412e-08 7.63854569789023 -0.283628172168107 0.125131161036674 1494.71595909691 811.34054949305 1.84227937335421 0.0674087462946843 -729.95912563911 2446.24978568747 -0.298399259924297 0.765811411431 RNASE1 other 1 1 1 1.84227937335421 -0.298399259924297 2.08663869583424e-10 307.126249106699 116.644297969201 2.63301553915471 0.00940028276097305 -1197.07254206083 242.085659658902 -4.9448304527724 2.12105835380606e-06 NEDD8 other 2.43573334964731e-06 0.0309144255067234 1 2.63301553915471 -4.9448304527724 3.41444945555166e-09 447.606480747899 165.747344807387 2.70053484879687 0.00770299357853143 -2003.22405324038 411.118993187563 -4.87261373576689 2.72664586134884e-06 DAD1 essential 3.74701683252239e-05 0.0397163236164072 1 2.70053484879687 -4.87261373576689 0.55413616623697 0.931139077121627 19.3757815976631 0.0480568524386099 0.96173485940651 -58.2521458535011 56.367923901712 -1.03342720152466 0.30306730373349 TEP1 other 1 1 1 0.0480568524386099 -1.03342720152466 9.90494347584998e-10 168.127353907371 62.9457026811832 2.67099018274412 0.0083545700924745 -302.286262897331 94.9332068675887 -3.1841994268555 0.00174873216449496 EPB41L4A other 1.11856526672774e-05 1 1 2.67099018274412 -3.1841994268555 0.813259735602854 -2.19165000166901 9.81204376149811 -0.223363251830258 0.823552708784794 -9.14183405000411 14.7944201661058 -0.617924457150958 0.537549865144016 CDO1 other 1 1 1 -0.223363251830258 -0.617924457150958 4.0748961940827e-09 558.659861002526 198.851726742358 2.80942926749816 0.00560706828499909 -893.046727008092 296.883377223121 -3.00807251440328 0.00307187248923388 REEP5 other 4.44611923736363e-05 1 1 2.80942926749816 -3.00807251440328 0.000410254650986962 247.65554921308 97.8929903283979 2.52985988457681 0.0124867389174458 -86.7053910565369 145.118021121363 -0.597481900501003 0.551124077296892 ITFG1 other 1 1 1 2.52985988457681 -0.597481900501003 0.0248103787412397 20.3170131902526 7.54344379120889 2.69333394038542 0.0078429428634636 21.9929298010282 33.2145766892404 0.662146924430099 0.508847831586026 QRICH2 other 1 1 1 2.69333394038542 0.662146924430099 0.144200652461066 589.734630002236 305.445230222172 1.93073772857176 0.0553174861603195 688.219511513534 1344.9074858091 0.511722567370126 0.609564189837901 FOXJ1 other 1 1 1 1.93073772857176 0.511722567370126 0.00921051665966348 280.288313842581 106.020506503885 2.64371792859064 0.00902668289762424 808.28531143734 467.702880185936 1.72820255268902 0.0859056067720861 SEC14L1 other 1 1 1 2.64371792859064 1.72820255268902 0.00355106504066483 246.595886429688 76.8629030099033 3.20825621688938 0.00161898458259907 441.190112899613 338.435449012731 1.3036167286454 0.194272608008971 RHBDF2 other 1 1 1 3.20825621688938 1.3036167286454 8.76424576118245e-40 487.252342284428 25.8310407881067 18.8630549686861 3.7655239251652e-40 239.461927279085 89.6548672156011 2.67093058877918 0.00846687546300168 ASH2L other 1.27651239511622e-35 1 5.48486214939563e-36 18.8630549686861 2.67093058877918 6.55264777855992e-18 86.1031593693996 17.5235266450569 4.91357482505886 2.31651935017101e-06 -106.205850246073 33.8270786123199 -3.1396695961617 0.00203738401063838 TTI2 essential 9.1258725612004e-14 1 0.0247265275437254 4.91357482505886 -3.1396695961617 0.0312922002102891 -0.960144927536229 2.03541028617681 -0.471720583342292 0.637802675034742 -7.3293115942029 3.17027811875211 -2.31188284423698 0.0221269193047331 CHRNA10 other 1 1 1 -0.471720583342292 -2.31188284423698 0.000849561526272579 325.620531425468 124.071999304935 2.62444816920522 0.00957084658297043 -88.3584884269075 208.504221342521 -0.423773139258203 0.672334313615705 CDKN1C other 1 1 1 2.62444816920522 -0.423773139258203 0.00331777491934866 32.0949657186874 17.9328349090051 1.78973184560857 0.0754245015957166 -64.9467362207425 36.2005229995312 -1.79408281536661 0.0747242916287917 SGO1 other 1 1 1 1.78973184560857 -1.79408281536661 0.00320564910628205 122.501949921639 50.5120542668691 2.4252022947716 0.0165647183338528 -82.7129788242154 75.4854698907948 -1.09574702182919 0.275057563998162 KLF16 other 1 1 1 2.4252022947716 -1.09574702182919 3.63174552077369e-07 769.528725484014 159.839763966484 4.8143760125007 4.00749461669329e-06 36.2736330957937 349.081484957397 0.103911650026986 0.917398379000299 TMEM8A other 0.00344071570638099 1 0.042086708464513 4.8143760125007 0.103911650026986 9.737924428528e-06 63.8259858064423 17.439504953981 3.65985077987391 0.000349670796863426 -30.5111001842079 26.0982274831524 -1.16908706554513 0.244235462108254 DOHH essential 0.0805521108727836 1 1 3.65985077987391 -1.16908706554513 1.33444080039684e-10 383.333258295439 70.6723245755576 5.42409296139124 2.28372930182377e-07 -463.547251361938 232.325888849444 -1.99524578882525 0.0478271946037053 MAU2 essential 1.57130404246728e-06 1 0.00259797045375473 5.42409296139124 -1.99524578882525 0.820355931258504 -2.046681113676 32.9696801671103 -0.0620776757099909 0.95059014907464 -28.7965421397277 49.2064196419405 -0.585219212234319 0.55934917352398 SHC2 other 1 1 1 -0.0620776757099909 -0.585219212234319 0.615803831221662 -6.92680548358217 14.0528053040914 -0.492912648662787 0.622852079809067 11.1723559617469 20.9734589912528 0.532690195089252 0.595098613858439 PLPPR3 other 1 1 1 -0.492912648662787 0.532690195089252 0.00286140088098452 7969.8241983937 2633.15784483574 3.02671722245002 0.00290751118611197 14453.9176016185 4516.88522083174 3.19997451672172 0.00167539242292041 INS-IGF2 other 1 1 1 3.02671722245002 3.19997451672172 0.000124548015728733 136.520547071473 61.1120088747056 2.23393977035468 0.0270613586737315 -213.767603965448 91.3260957771676 -2.34070669666021 0.020649041927885 ABHD17A other 0.902848566017586 1 1 2.23393977035468 -2.34070669666021 0.665561665951111 3.23638389747876 5.83680295350496 0.554478868527734 0.580076939852926 -12.499547290709 26.8557721417353 -0.465432430121195 0.64229684903762 LBP other 1 1 1 0.554478868527734 -0.465432430121195 0.90213076304722 -8.62839822275771 20.9633414046623 -0.411594604896276 0.681205168065843 -16.2223184476742 41.743301349468 -0.388620878637836 0.698089912854647 SYT5 other 1 1 1 -0.411594604896276 -0.388620878637836 0.106721877886458 40.4542885993359 19.3245738091789 2.09341168394207 0.0379513314664221 31.6825510871184 38.1063979570897 0.831423403565853 0.407021762619663 TNNI3 other 1 1 1 2.09341168394207 0.831423403565853 0.808335274190781 17.8865271419228 27.6680705375779 0.646468177736856 0.519019694203285 15.3997165903639 48.2339120800977 0.319271564885531 0.749989790674562 CBFA2T3 other 1 1 1 0.646468177736856 0.319271564885531 0.192113481675045 28.5575422626789 39.6992002295788 0.719348049772584 0.473134171025034 -69.5577382773654 59.5650151303309 -1.16776161518922 0.244902102610654 GAMT other 1 1 1 0.719348049772584 -1.16776161518922 1.76157466736175e-17 100.411150611289 12.6200262485349 7.95649300832055 6.37951244433911e-13 -22.5999710974306 26.0479562823572 -0.867629339225281 0.387136918731485 ERMARD other 2.44348022109748e-13 1 8.69017185167874e-09 7.95649300832055 -0.867629339225281 4.64460888064186e-18 620.203607040667 70.7883724164316 8.76137684579259 7.14063155363473e-15 26.2327205988619 146.108446503152 0.179542806912918 0.857780710159699 PHF10 other 6.47876492760734e-14 1 9.95047006999e-11 8.76137684579259 0.179542806912918 0.470120074427859 2.96452935184029 2.51228778596775 1.18001184752739 0.239803332112323 0.719205290613102 11.1903337831303 0.0642702268360682 0.948837872738046 KCNA5 other 1 1 1 1.18001184752739 0.0642702268360682 0.106127887506089 2.68327129427226 1.80493140873703 1.48663338744259 0.139142970990562 -7.68859027295305 8.32640562736946 -0.923398476730479 0.357234803194385 CRACR2A other 1 1 1 1.48663338744259 -0.923398476730479 0.0445491293472282 56.8917049201527 63.5006531575346 0.895923145530705 0.371683094086665 -144.935044503351 94.561303229602 -1.53270988822391 0.127385886136681 NXNL2 other 1 1 1 0.895923145530705 -1.53270988822391 3.12814999188915e-09 1087.62804878049 175.096687938747 6.21158550503804 4.45295270700087e-09 285.227351916376 389.998058917521 0.731355824457315 0.465645113763966 SH3BP4 other 3.44002654608049e-05 1 5.49405304989768e-05 6.21158550503804 0.731355824457315 3.41636084765013e-09 184.07060572278 35.8000021264945 5.14163672595301 8.26742751162019e-07 -186.798773690078 125.904189926601 -1.48365811970974 0.139970258033494 DOCK6 other 3.74877275812649e-05 1 0.00907515517950548 5.14163672595301 -1.48365811970974 1.0261991314455e-16 302.617666053546 39.101481226305 7.73928906432228 1.40116133197958e-12 -240.965648886164 141.211593917947 -1.7064154734078 0.0900140964516877 ECSIT other 1.41143428539015e-12 1 1.89773290803315e-08 7.73928906432228 -1.7064154734078 1.06441826214834e-12 251.100136827982 44.4183307563788 5.65307458772349 7.7905959983527e-08 -435.364908936329 161.416108223427 -2.69715899935904 0.00779943911212462 ELOF1 other 1.35032100736139e-08 1 0.000910331142407513 5.65307458772349 -2.69715899935904 3.44023739848797e-07 5.48885172798217 1.36083573560886 4.03344179194881 8.67477656012058e-05 -8.76254180602006 4.78589136139194 -1.83091113950224 0.0690720600154523 ANGPTL8 other 0.00326547333864478 1 0.798599930124701 4.03344179194881 -1.83091113950224 5.243151743807e-20 3632.92245816121 393.121457354954 9.24122148560566 2.34151148273842e-16 -1373.03535421652 1412.95387308445 -0.971748179733004 0.332750704342789 PRKCSH other 7.40857341399928e-16 1 3.29708231884397e-12 9.24122148560566 -0.971748179733004 0.151170413316841 49.8212734301313 25.6356040998434 1.94344058505864 0.0538476623581979 100.568915472189 93.1597242689946 1.07953212894664 0.282094958926163 CNN1 other 1 1 1 1.94344058505864 1.07953212894664 2.03237161346182e-09 396.599104258633 71.2111275645114 5.56934172822003 1.26493233907565e-07 -187.299687262712 129.02451794687 -1.45165965541401 0.148833502996721 CDC16 essential 2.25857457404012e-05 1 0.00146188230426973 5.56934172822003 -1.45165965541401 0.00398293334820134 434.930365801344 135.248781519911 3.21578028957928 0.00164435992092006 -43.7693430135061 584.317913543113 -0.0749067279969274 0.940404960329339 THEM6 other 1 1 1 3.21578028957928 -0.0749067279969274 0.755202129359418 1.05654414686364 5.97734554365171 0.176758084194371 0.859926228367837 14.2069829356134 19.1732031300677 0.740981193347594 0.459811668669202 EXOC3L2 other 1 1 1 0.176758084194371 0.740981193347594 2.19339832715352e-17 925.280593256265 121.911254660425 7.58978812771278 2.72993137229263e-12 -1830.28272913962 514.25859316973 -3.55907077382671 0.000493453720697841 NECTIN2 other 3.0389533822712e-13 1 3.68185844181107e-08 7.58978812771278 -3.55907077382671 0.744058589081145 228.13617369968 315.075464215811 0.72406835698072 0.47010822153831 646.448261457759 1329.08372915401 0.486386408378678 0.627375811357489 APOE other 1 1 1 0.72406835698072 0.486386408378678 4.01564176733678e-14 358.018114539731 53.9506292583737 6.63603222911739 5.02578663328162e-10 -706.607055856989 227.580093243346 -3.10487198500895 0.00226133358081628 TOMM40 essential 5.29422210605681e-10 1 6.40586764278076e-06 6.63603222911739 -3.10487198500895 0.559034050593245 -16.9451532255986 42.863434614622 -0.395328871285038 0.693136820674058 147.690854628985 180.440252431449 0.818502815413064 0.414310734430894 APOC1 other 1 1 1 -0.395328871285038 0.818502815413064 0.674253438490372 1.57041792423049 17.1549214580562 0.0915432885000473 0.927179880118818 -18.4116140207176 26.2145895430354 -0.702342258324967 0.483525968964331 GADD45G other 1 1 1 0.0915432885000473 -0.702342258324967 0.573576094115047 -12.4450811599955 26.658265453335 -0.466837618590769 0.641275839557143 -83.8667818337044 79.8616206084636 -1.05015126408312 0.295293743804419 DPP6 other 1 1 1 -0.466837618590769 -1.05015126408312 1.03487553459359e-24 654.562836527717 92.077833580316 7.10879927422235 4.71460276718087e-11 -339.03814521419 163.381102743534 -2.07513683970167 0.0397166418795748 XPO7 other 1.48908240672671e-20 1 6.19781679773597e-07 7.10879927422235 -2.07513683970167 1.54797225437994e-13 90.6543250755916 12.5376535756332 7.23056547453005 2.14901726187341e-11 -45.27364261378 47.5491514092164 -0.952144071387248 0.342525671908218 FAM98C other 2.01019676953779e-09 1 2.8468031668037e-07 7.23056547453005 -0.952144071387248 1.57231665291288e-06 218.667439896821 62.4768063077153 3.49997787690721 0.000607734056287639 -86.828013509877 113.288961828455 -0.766429598334161 0.444586419602753 SAFB2 other 0.0140989634266698 1 1 3.49997787690721 -0.766429598334161 0.00010413959692539 2599.14645409195 1260.66825566856 2.06172118827055 0.0409042229553437 -3772.27794256438 2360.4754415245 -1.59810090636998 0.112057098650848 RPL36 essential 0.761885291106155 1 1 2.06172118827055 -1.59810090636998 0.575169651270161 12.7612940554726 12.8459284649572 0.993411577083315 0.322211170227466 14.6776296606772 19.1970206010181 0.764578523184935 0.445800265429728 ATP8B3 other 1 1 1 0.993411577083315 0.764578523184935 3.48688383484795e-05 113.130518610961 24.6544567588241 4.58864373762649 9.44422706042862e-06 91.8977781828636 78.6711076714125 1.16812615079344 0.244634163676758 GDF1 other 0.27107034932108 1 0.0961044545669216 4.58864373762649 1.16812615079344 2.15852613226814e-09 2604.16243654822 406.782468005603 6.40185514709143 2.06299409166805e-09 827.916113018812 889.033586889731 0.931254032724751 0.353291706507195 KIF1A other 2.39380548068537e-05 1 2.57771111753923e-05 6.40185514709143 0.931254032724751 1.960454219166e-50 146.192860250139 6.57632609377445 22.2301720087351 6.3682565274334e-50 -50.0213009447143 66.1766902346348 -0.755874927672565 0.450878825978308 GTPBP3 other 2.86030270576319e-46 1 9.29064944787259e-46 22.2301720087351 -0.755874927672565 0.00467269831780365 59.9505913036348 18.0054453074518 3.329581150588 0.00108995496525222 164.350097353343 184.420475216091 0.891170555551214 0.374236970463803 PLVAP other 1 1 1 3.329581150588 0.891170555551214 2.12046302487238e-11 1875.57781523186 254.547080405551 7.36829435342036 1.02824797600622e-11 -754.730066083867 2607.61126484967 -0.289433504241046 0.772644069600232 BST2 other 2.57678666782492e-07 1 1.37034607762349e-07 7.36829435342036 -0.289433504241046 9.00286194538377e-23 530.473188412991 45.4213914903025 11.6789286062768 7.37549503746347e-23 162.930360962067 315.584917231657 0.516280570032651 0.60641368880886 SLC27A1 other 1.28803945852606e-18 1 1.06273507994811e-18 11.6789286062768 0.516280570032651 0.00140541455600104 111.365388161534 30.1661566577939 3.69173273960178 0.00031321041907419 40.8567213719342 120.011792481293 0.340439222906389 0.73401180304885 NSUN5 other 1 1 1 3.69173273960178 0.340439222906389 2.79694769833023e-07 9.18374922873065 1.59293599174999 5.76529708431124 4.27870578244821e-08 15.8326117961219 16.049196621894 0.986504942840776 0.325422821893376 USHBP1 other 0.00267611955776236 1 0.000506513190526219 5.76529708431124 0.986504942840776 1.49032768894284e-20 569.344333443398 52.9655812660407 10.7493266350395 1.98195558033524e-20 20.6957344370302 363.373775014035 0.0569543975379921 0.954655833703876 COLGALT1 other 2.111794335232e-16 1 2.84093512885254e-16 10.7493266350395 0.0569543975379921 1.08658020984536e-41 488.94622609065 26.0920627388499 18.7392706734003 1.12884739636606e-41 9.49846567977897 262.88353539338 0.0361318393925486 0.971223725643305 DDA1 other 1.58314736574468e-37 1 1.64506931072427e-37 18.7392706734003 0.0361318393925486 9.15098770811633e-23 331.796543575452 28.6509329180886 11.5806540933253 9.72449942586671e-23 -124.471170805812 288.664741197754 -0.431196308525056 0.666924734530114 MRPL34 essential 1.30914030152312e-18 1 1.40071689730184e-18 11.5806540933253 -0.431196308525056 2.41950664390324e-07 468.620732125418 89.5257115352379 5.23448207324179 5.45243426673791e-07 -586.661326518223 622.018906465806 -0.943156743983108 0.347107309886508 PGLS other 0.00232950099675004 1 0.00605929020062584 5.23448207324179 -0.943156743983108 0.0031874825984874 131.178112585195 83.5480749247666 1.57009138395251 0.118635252036753 -254.012633487626 124.854666588048 -2.03446647553614 0.0437791131084753 LSM7 essential 1 1 1 1.57009138395251 -2.03446647553614 5.35690762985417e-18 310.355550201871 37.800582325026 8.21033780731993 8.54570195545658e-14 -13.7584694369218 79.554278023581 -0.172944432137811 0.862923683916843 TULP4 other 7.46699354525372e-14 1 1.17546130397305e-09 8.21033780731993 -0.172944432137811 7.37637669922298e-09 303.380199262637 62.4271157157424 4.85975037905095 2.88458847438801e-06 -89.8679521337393 131.684296263379 -0.682450031505629 0.495986362752545 SNX9 other 7.92222857496548e-05 1 0.0305968299478336 4.85975037905095 -0.682450031505629 2.5969433852192e-09 30.7453662128818 5.70920803397216 5.38522436560975 2.73803266209767e-07 0.656895658360199 11.8103154532218 0.0556205006514876 0.955718148962315 RTN4IP1 other 2.8683239689746e-05 1 0.00309972677676077 5.38522436560975 0.0556205006514876 1.1771957204571e-11 89.5320562268936 19.9835166389446 4.48029532762068 1.46937947368158e-05 -95.1450789805583 41.3387695747424 -2.30159436188665 0.0227346222630751 QRSL1 essential 1.44394827071268e-07 1 0.146658765268159 4.48029532762068 -2.30159436188665 8.76679284812241e-09 64.3541824268332 14.6648080170722 4.38834128288037 2.14249372364522e-05 -34.6932662722864 30.6077940442894 -1.13347816644628 0.258821874509585 C6orf203 other 9.3822217060606e-05 1 0.210649982908798 4.38834128288037 -1.13347816644628 2.66999348018617e-12 168.605066220075 26.4204721995735 6.38160684436204 1.95403851625022e-09 -12.0380573287057 55.1905664369333 -0.218118024616791 0.827625914200231 RSPH3 other 3.34710382676139e-08 1 2.44332976071927e-05 6.38160684436204 -0.218118024616791 1.35944078980142e-13 939.330376637556 138.593846556183 6.77757634973189 2.36838151193605e-10 92.144915999515 262.260394818883 0.351348956304097 0.725800653596469 MLLT1 other 1.76740897082083e-09 1 3.05000171107124e-06 6.77757634973189 0.351348956304097 5.21312958647512e-10 1070.82162162162 212.497515948697 5.03921947906509 1.34469445760524e-06 -538.383579806222 440.096062283392 -1.22333196305569 0.223148542397109 AFDN other 5.97059731538996e-06 1 0.0145764879204408 5.03921947906509 -1.22333196305569 1.00960774913419e-16 3137.49823128106 520.97100334271 6.02240472339134 1.22684658496014e-08 -8526.42309348005 2007.7503486402 -4.24675463224539 3.75048196072117e-05 ACTN4 other 1.38871545893408e-12 0.540594469818349 0.000148767416892266 6.02240472339134 -4.24675463224539 3.12743974443623e-08 61.0662313654865 20.6615981206853 2.95554250009104 0.00360584334204403 -81.3367845364942 32.3691633192718 -2.5127861271616 0.0129940619058348 STK33 other 0.000322751781625819 1 1 2.95554250009104 -2.5127861271616 9.01605402927424e-09 236.651437347255 92.6039372070664 2.55552241605119 0.011611568681109 -842.673090272826 204.863868131285 -4.11333193090353 6.44649395582455e-05 NDUFA10 other 9.63996496810002e-05 0.926425646391546 1 2.55552241605119 -4.11333193090353 0.000862443711060214 881.036526080675 265.37741709594 3.31993782938267 0.00112724141664753 -831.227197477337 859.101750858007 -0.967553839399313 0.334804222101345 ARPC1B other 1 1 1 3.31993782938267 -0.967553839399313 0.504693938374222 -6.17650689127567 6.30428529375417 -0.979731500634165 0.328745385829625 -14.2039452440088 13.0384742482925 -1.08938706887955 0.277674035196592 CACNG6 other 1 1 1 -0.979731500634165 -1.08938706887955 5.00454714966665e-11 86.2032107461715 41.8781708315022 2.05842827025593 0.0412341380499926 -211.34831509111 57.4569597018646 -3.67837623479844 0.000323878511500914 ZSWIM6 other 5.99494703058568e-07 1 1 2.05842827025593 -3.67837623479844 3.13442234082358e-08 295.250973558803 48.3721720128785 6.10373612084642 8.45651881382986e-09 185.583580848283 259.456623632909 0.715277868993066 0.475549219518204 FCHO1 other 0.000323441041349586 1 0.000103245638198049 6.10373612084642 0.715277868993066 1.81425941120282e-05 37.7582758792927 7.87201994434424 4.79651679572035 3.79905387351678e-06 35.9605518241431 53.5378412068859 0.671684756305003 0.502797332308306 UNC13A other 0.14581202887837 1 0.039962247695523 4.79651679572035 0.671684756305003 9.01758450654848e-26 661.776237959854 53.6110596747457 12.3440245720715 1.20722399754936e-24 -121.748865891692 288.592029772112 -0.421871892955021 0.673718530189624 MAP1S other 1.30060621337949e-21 1 1.74286928526201e-20 12.3440245720715 -0.421871892955021 0.0930008336158436 74.3801820960988 35.0023017397735 2.12500831085574 0.035367882266772 49.8780354888017 55.8778647383778 0.892626010716989 0.373611379912876 KLHDC7B other 1 1 1 2.12500831085574 0.892626010716989 7.43457601108646e-05 377.944959128065 108.547175098196 3.48184979283121 0.000667258587345879 -10.0806539509533 173.28530029149 -0.0581737396882267 0.953694389575113 SCO2 other 0.554768061947272 1 1 3.48184979283121 -0.0581737396882267 2.7273184659888e-05 1641.61236904196 351.029798877914 4.67656128992314 6.4543916135607e-06 920.952976473675 1035.02983157918 0.889783993055105 0.375006697271729 PXDN other 0.215267246520496 1 0.0666286846267871 4.67656128992314 0.889783993055105 6.46439533163141e-09 481.339954463375 82.7526720893202 5.81660920802453 3.61055344437218e-08 -36.3123906728429 288.932705519273 -0.125677675040566 0.900158794305411 SSBP4 other 6.97185036516447e-05 1 0.000429042065794747 5.81660920802453 -0.125677675040566 0.036411747627858 103.153129320784 45.3706478276923 2.27356527313731 0.0243833262892033 -21.8641641772043 158.314129137201 -0.138106208816371 0.890338073512695 GDF15 other 1 1 1 2.27356527313731 -0.138106208816371 1.2922493977714e-05 158.120173675157 41.8885707722323 3.77478082350745 0.000228625227014756 -172.886292512072 146.163939024921 -1.18282453021873 0.238713473188921 PGPEP1 other 0.105563853303946 1 1 3.77478082350745 -1.18282453021873 0.00761371429093343 110.664157959717 55.5580148171268 1.99186666989408 0.0481652458984075 -260.652599353973 193.861431420794 -1.34453045891424 0.18076686830251 KIAA1683 other 1 1 1 1.99186666989408 -1.34453045891424 1.01749514394448e-08 1036.49175590735 171.719631593349 6.03595375956712 1.14652146703456e-08 364.194536308648 599.190120333021 0.607811317226381 0.544213750608992 LSM4 essential 0.000108373407781527 1 0.000139210636527336 6.03595375956712 0.607811317226381 5.87170751444713e-11 2152.94566655909 339.042007417041 6.3500852975745 2.32968244850083e-09 -795.039941437186 1183.03667051446 -0.672033218624955 0.502576088160547 JUND other 7.01610330901287e-07 1 2.90455239548213e-05 6.3500852975745 -0.672033218624955 0.00710326236171033 108.026741052667 111.942892306221 0.965016526079734 0.336020621351348 -366.796042818646 196.797801249299 -1.8638218541578 0.0642141859639676 TRPM4 other 1 1 1 0.965016526079734 -1.8638218541578 0.00226624371296624 36.3951805373778 10.8191334560193 3.36396446955083 0.000968277427032566 17.4258372469011 16.6762972072016 1.04494643087651 0.297674621664562 SULT4A1 other 1 1 1 3.36396446955083 1.04494643087651 1.46702641424101e-30 115.827715759202 8.73886035046912 13.2543273509325 2.7408685651853e-27 13.4385957353895 28.8057922706393 0.466524079918711 0.64149544181802 ZNF557 other 2.12674819272519e-26 1 3.97014811667091e-23 13.2543273509325 0.466524079918711 1.87997891904705e-11 137.539491936191 38.7036757779836 3.55365450881619 0.000503809778161151 -211.283516825179 71.7678616070784 -2.94398512222552 0.00373909272521641 CRB3 other 2.28906233183169e-07 1 1 3.55365450881619 -2.94398512222552 0.695993239350212 11.7386248614672 82.6630886377819 0.142005640666346 0.887266103345314 87.8710708979678 111.608799221286 0.787313110714028 0.43234084851574 OLFM1 other 1 1 1 0.142005640666346 0.787313110714028 1.52741990779755e-07 328.069296003718 62.9917748343584 5.20812910679848 6.42292155730439e-07 29.7254298327134 91.5469523595767 0.324701468116146 0.745875000066756 CAMSAP1 other 0.00149702425163238 1 0.00710310895022292 5.20812910679848 0.324701468116146 0.00230550534353752 51.4294659940859 71.16635562719 0.722665444096966 0.47107398925769 -270.092415049164 103.692937243242 -2.60473299560975 0.0101730948074214 UBAC1 other 1 1 1 0.722665444096966 -2.60473299560975 0.000176575993304409 181.000343349232 50.6654409534702 3.57246162162999 0.000516155623754015 -100.828965683636 173.878542353368 -0.579881590442163 0.563119088953757 ZBTB46 other 1 1 1 3.57246162162999 -0.579881590442163 0.0606159969386336 494.861045637608 213.426835585734 2.318644908357 0.0221656294029896 358.254922885618 732.458780035499 0.489112742792508 0.625685423212899 HELZ2 other 1 1 1 2.318644908357 0.489112742792508 0.00226478016535958 151.23066280507 58.99898144245 2.56327582455955 0.0116479385430857 -225.863399066575 202.718175658927 -1.1141743868423 0.267507595049529 SAMD10 other 1 1 1 2.56327582455955 -1.1141743868423 0.169102797947419 33.9550916559375 28.353788371686 1.1975504370289 0.232968580187984 92.1508491202252 48.6377251944229 1.89463731603122 0.0600521861058088 TNNT3 other 1 1 1 1.1975504370289 1.89463731603122 0.339820494283996 -533.910371136952 1414.18555540241 -0.37753912073089 0.706303121366553 1915.79754875104 1903.01817606672 1.00671531824816 0.315682092871119 COL5A1 other 1 1 1 -0.37753912073089 1.00671531824816 3.44217915337092e-09 694.475526431452 132.750791314892 5.23142287554517 5.41539126718259e-07 -54.712302713072 207.092010259795 -0.264193208827496 0.791984269258637 ATXN10 other 3.7760705312479e-05 1 0.00602083201085361 5.23142287554517 -0.264193208827496 0.00499673726794342 299.360036556184 95.4167906810738 3.13739368531878 0.00207293692269541 116.772074982036 181.698209170472 0.64267047823503 0.521474262632436 TUBGCP2 essential 1 1 1 3.13739368531878 0.64267047823503 0.719581319584585 -8.58557565525566 19.1443449543383 -0.448465365398155 0.654500940389739 -29.5580980552203 36.4557764845785 -0.810793265306636 0.418841226141037 CYP2E1 other 1 1 1 -0.448465365398155 -0.810793265306636 0.131722504224544 38.9037283274667 19.8077429714507 1.96406669773226 0.0518343571317169 14.8973313220474 30.8647501376955 0.48266489297942 0.630213025053296 PNPLA7 other 1 1 1 1.96406669773226 0.48266489297942 5.06475952585424e-23 687.975352637632 77.4494819456586 8.8828916004931 1.59754290132182e-15 -918.005247007669 286.782038403113 -3.20105558953201 0.00166334556287483 PAK4 other 7.25374859292845e-19 1 2.23671981614069e-11 8.8828916004931 -3.20105558953201 0.714520299663022 -3.49358452138493 6.83721468077206 -0.510966041655786 0.610126071571438 -15.2341215961379 19.4285948336874 -0.784108255205536 0.434213055734373 MNX1 other 1 1 1 -0.510966041655786 -0.784108255205536 0.00891118047856737 44.2580143773072 24.4266675303179 1.81187279527078 0.0720331545391374 -171.195259374393 94.2152594303951 -1.81706509549941 0.0712301607308973 ZNF337 other 1 1 1 1.81187279527078 -1.81706509549941 4.01526739390547e-10 149.919035428362 28.2757030269649 5.30204448976539 3.90996478445438e-07 -41.3756376782828 59.7664103109229 -0.692289154778315 0.489798291606731 CEP85 essential 4.62679261799727e-06 1 0.00438346151985181 5.30204448976539 -0.692289154778315 0.665620335294063 1.58499449675917 24.4717091463495 0.0647684429101514 0.948467965470131 -66.6473121473121 85.630170207272 -0.778315773354054 0.437940764572341 GATA5 other 1 1 1 0.0647684429101514 -0.778315773354054 0.205097212533968 -18.9620276384982 14.8051758979904 -1.28077016910498 0.20278602719365 -87.6890406890406 51.8055246779786 -1.69265809455869 0.0931593054649631 RBBP8NL other 1 1 1 -1.28077016910498 -1.69265809455869 2.6083427615142e-05 244.911132972619 53.1590634053264 4.60713784788164 9.61430471905894e-06 82.7829589550204 191.831477487059 0.431540016474121 0.66679058089354 OSBPL2 other 0.206238369525277 1 0.0977678646881103 4.60713784788164 0.431540016474121 0.0034731948090687 264.663941842689 132.699996940012 1.99445326259 0.048313815128689 -744.528657452184 453.441943053228 -1.64194924809765 0.103154900155663 ADRM1 essential 1 1 1 1.99445326259 -1.64194924809765 0.0429409777536372 1425.84243896024 1497.71551976765 0.952011526983069 0.342545225120738 -2803.07548958737 2057.90852018673 -1.36209917112012 0.175105318840608 ASS1 other 1 1 1 0.952011526983069 -1.36209917112012 8.17062160187375e-07 127.722065186568 31.2347563037336 4.08910074228115 6.87826768836998e-05 -27.8973230757033 43.1344946547969 -0.646752055378511 0.51873085424266 EXOSC2 essential 0.0075071671278016 1 0.64009159107971 4.08910074228115 -0.646752055378511 7.52313974428207e-12 200.93645320197 36.5925470342608 5.49118521358564 1.57456770088293e-07 -61.5524261083746 51.0905215076624 -1.20477192817738 0.230104300040321 POMT1 other 9.28762609977579e-08 1 0.00181075285601537 5.49118521358564 -1.20477192817738 9.20767696587489e-08 98.7605911330045 34.6931021725577 2.84669242438413 0.00500832295963741 -124.872512315271 48.4385162108296 -2.57795907231676 0.0108578548989901 UCK1 other 0.000918926161194314 1 1 2.84669242438413 -2.57795907231676 0.138830388837097 -4.29057781649245 12.7684135601548 -0.336030611499118 0.737293610014085 -31.8509606078203 17.773587284289 -1.79203894511351 0.0750403510078578 FIBCD1 other 1 1 1 -0.336030611499118 -1.79203894511351 5.5748022609252e-12 3473.43349753694 502.583847089376 6.9111522737006 1.13638266691447e-10 774.857635467971 701.707668096523 1.10424564344562 0.271176108409158 PRRC2B other 6.91108236286897e-08 1 1.47786565832226e-06 6.9111522737006 1.10424564344562 0.000210997280441823 289.452526363203 122.008861687491 2.37238936877058 0.0190951608419933 -284.121456202639 212.816159685752 -1.33505583702938 0.184121764784752 CHMP2A essential 1 1 1 2.37238936877058 -1.33505583702938 3.28397446841459e-08 421.711793227704 116.843727729481 3.60919495999016 0.000432691334174085 -376.145885220709 203.806781530732 -1.84560043780481 0.0671573924992739 UBE2M essential 0.000338512088204176 1 1 3.60919495999016 -1.84560043780481 3.25552439189583e-12 4143.75131816014 729.38982233447 5.68112028887069 7.97563646402577e-08 -1321.57281013195 1272.25136564822 -1.03876705957285 0.300783828042134 TRIM28 other 4.06745217523465e-08 1 0.000931235313539649 5.68112028887069 -1.03876705957285 0.00542966692304507 159.119736795521 161.061890640558 0.98794156806857 0.325002507023571 -698.022977285715 345.759297471327 -2.01881187979797 0.0455478759880241 METTL26 other 1 1 1 0.98794156806857 -2.01881187979797 1.49361137284977e-19 734.572279472945 80.5797373035409 9.1160917626951 3.97230985827243e-16 -486.028463454999 326.096815635814 -1.49044222497959 0.13815335025144 YIPF2 other 2.10509586889447e-15 1 5.58705381566018e-12 9.1160917626951 -1.49044222497959 3.77123621303937e-12 165.860099217825 24.4902476695468 6.77249578917365 2.47299172770279e-10 -82.3076192550829 98.3131831733297 -0.837198192535091 0.403770145759785 ATG4D other 4.70197731041748e-08 1 3.18224575520795e-06 6.77249578917365 -0.837198192535091 2.59699822447059e-06 84.6688894482943 35.2411431879248 2.40255797029041 0.0174556412629437 -165.979594248167 67.9150258227095 -2.44393037089396 0.0156427392950198 TMEM160 other 0.0227523014445869 1 1 2.40255797029041 -2.44393037089396 4.59143364216865e-07 149.374367457655 57.3556827834504 2.60435165634111 0.0100943681331057 -286.053187499678 110.533096402272 -2.58794150177989 0.0105668284314688 ZC3H4 other 0.00431365190681745 1 1 2.60435165634111 -2.58794150177989 6.38309953978206e-05 6.54798074502569 2.43165458396285 2.69280875179011 0.0078597954239229 -6.60985730015942 4.68616704574819 -1.41050398665507 0.160381819569451 NPAS1 other 0.479689930414622 1 1 2.69280875179011 -1.41050398665507 0.30606862824848 -6.4334892297987 7.17588662555995 -0.896542764051359 0.371362292355481 18.2770275225917 26.5344009809772 0.688804979456468 0.491982407925487 GMFG other 1 1 1 -0.896542764051359 0.688804979456468 1.08665747320368e-19 133.389321132331 13.8964606607401 9.59879816802412 1.96364619207198e-17 -3.68160579989262 50.0003364810525 -0.0736316204849493 0.941397837469441 MAP3K10 other 1.53273036595379e-15 1 2.78229028954679e-13 9.59879816802412 -0.0736316204849493 8.5108302162855e-06 68.2634858305062 25.9865830933835 2.62687424449761 0.00959148361168551 -128.988691418829 57.9658037491162 -2.22525494474482 0.0276871001065521 ARHGEF16 other 0.0708101073994954 1 1 2.62687424449761 -2.22525494474482 3.26831958904578e-20 441.373215078242 52.6167068362313 8.38846141496483 4.13850177990354e-14 -174.432911019393 117.867816185899 -1.47990279843889 0.14108365552308 LRRC47 other 4.62238439478745e-16 1 5.71196015662286e-10 8.38846141496483 -1.47990279843889 0.0091078651184676 45.1979858385003 38.2919852797142 1.18035107107504 0.239716658256528 -145.401144660087 84.8160893171393 -1.71431087934757 0.088523402876591 SESN2 other 1 1 1 1.18035107107504 -1.71431087934757 2.97670341614447e-05 245.098599406183 99.6626374071361 2.45928269392391 0.0150504786635851 -393.856682620498 209.956610519348 -1.87589560360236 0.0625998737891611 SMPDL3B other 0.233373547825727 1 1 2.45928269392391 -1.87589560360236 0.00061365867593876 87.7562594429456 194.725632914399 0.45066619185941 0.652876592422368 -1285.51854902994 431.31393039456 -2.98047073938458 0.00335549324990571 ATPIF1 other 1 1 1 0.45066619185941 -2.98047073938458 1.0587336448614e-10 76.2053133973926 16.2544466944681 4.68827483517649 6.11078409617504e-06 -72.2827230369513 36.0033200829899 -2.00766826143631 0.0464623620897635 MED18 essential 1.25269364860001e-06 1 0.0632282830431231 4.68827483517649 -2.00766826143631 2.92190146967389e-06 599.321660649819 136.868847862799 4.37880255447605 2.21878602803361e-05 50.7955234657039 288.328376782192 0.17617247401242 0.86039449576097 THEMIS2 other 0.0254497618008596 1 0.217729472930938 4.37880255447605 0.17617247401242 0.000266351472070083 129.652900130832 44.6902996242002 2.90114188584728 0.00426672908190441 -111.268948975142 99.7391098875195 -1.11559997979354 0.266342529564037 CLIP1 other 1 1 1 2.90114188584728 -1.11559997979354 7.23373915454218e-09 259.21160295104 48.6816214805896 5.32462960491964 3.80289104841087e-07 -71.722035919219 108.647128801579 -0.660137425722534 0.510220178727269 HIP1R other 7.77626959113285e-05 1 0.00426646346721216 5.32462960491964 -0.660137425722534 1.25875317625123e-25 281.267063524423 25.8071324982523 10.898811153989 1.04714538979868e-20 -183.409888145913 101.859170709201 -1.80062224018623 0.0737850992273077 ZNF317 other 1.81512208015428e-21 1 1.50244420528314e-16 10.898811153989 -1.80062224018623 5.25543634634631e-31 317.393202332015 24.0898986566073 13.1753647807464 5.64075950875736e-27 -30.1758709236584 83.1501545443259 -0.36290817604641 0.717174345121507 PPAN other 7.62353596400996e-27 1 8.1689479205824e-23 13.1753647807464 -0.36290817604641 1.27387095291717e-19 1174.84385090977 133.996376347873 8.76772852319315 3.28388101088123e-15 -708.479291799375 462.510015526752 -1.53181394567746 0.127633430267094 EIF3G essential 1.79590326942262e-15 1 4.58758177220108e-11 8.76772852319315 -1.53181394567746 1.24284276084873e-06 43.5625544155086 9.96299248297267 4.37243674427734 2.26003580172967e-05 -29.1850788542711 34.3888688155986 -0.848678071115644 0.397386302957182 ANGPTL6 other 0.0112415127718768 1 0.22155130964356 4.37243674427734 -0.848678071115644 1.70546998937264e-06 206.429009114254 46.2790005257868 4.46053300133893 1.57499571090614e-05 -94.5257337139206 159.739403669955 -0.59174963435587 0.554891615553547 C19orf66 other 0.0152332579450764 1 0.156743573149379 4.46053300133893 -0.59174963435587 4.87217184339592e-09 517.4486110571 94.1482806977843 5.49610260773756 1.57533195292566e-07 -222.075634195346 332.885861197447 -0.667122458720543 0.505692278160061 DNMT1 other 5.29458914221835e-05 1 0.00181147421266921 5.49610260773756 -0.667122458720543 2.21499467662306e-31 188.264142233278 14.4533519116913 13.0256388541257 2.5303276964669e-26 -58.4372147307168 50.1835000990894 -1.16447068489305 0.246106939949373 ZNF426 other 3.21417877524772e-27 1 3.66087811124831e-22 13.0256388541257 -1.16447068489305 5.40646797946398e-07 70.8801147516233 20.8862330608603 3.39362845109915 0.000875761155089454 -96.9760156296471 47.5181495307218 -2.04082054093772 0.0429653106256134 ZNF331 other 0.00504531591843579 1 1 3.39362845109915 -2.04082054093772 4.74709467501516e-12 117.845153244791 24.1646256175109 4.87676304653339 2.92696067285811e-06 -55.7018425842415 45.1691461512404 -1.2331834300727 0.219603792208412 ZNF236 essential 5.89826513370634e-08 1 0.0310287100929689 4.87676304653339 -1.2331834300727 0.0422855963475207 13.7234887281006 6.01749884062794 2.28059682129802 0.0239621832185858 -8.47263682633557 27.8822042180758 -0.303872561870228 0.761640555787635 SLC7A10 other 1 1 1 2.28059682129802 -0.303872561870228 2.29069027061555e-06 339.563998812715 72.1548331559456 4.70604648310707 5.63692603486867e-06 -255.603257651606 330.572844589746 -0.773213111224605 0.440597048947768 LRP3 other 0.0202061788770998 1 0.0584887445377974 4.70604648310707 -0.773213111224605 4.23615076848039e-11 103.649246328683 20.7781742253696 4.98837122090012 1.635481001392e-06 -109.187221012227 45.1312484437291 -2.41932640415131 0.0167224062621171 C12orf65 other 5.08973514832918e-07 1 0.0176304851950057 4.98837122090012 -2.41932640415131 5.61019458851349e-15 404.342585936045 44.8299735507397 9.0194696518926 6.53602419816887e-16 123.029754772745 181.413713886441 0.678172295451476 0.498667156251587 NOL11 essential 7.51878278752578e-11 1 9.17853878148855e-12 9.0194696518926 0.678172295451476 2.43355851841096e-24 956.868849028595 91.5281783260318 10.4543635252975 1.30030034905463e-19 27.9510799552721 198.506529728929 0.140806854028635 0.888208958447261 UBE4B other 3.49751030266024e-20 1 1.85981958925283e-15 10.4543635252975 0.140806854028635 1.99948927627291e-07 213.147428566704 53.1868825034091 4.00751874398809 9.50428156899757e-05 -151.566646734143 121.847504851905 -1.24390439441791 0.215412648158797 CASZ1 other 0.00194190398511625 1 0.871827748324147 4.00751874398809 -1.24390439441791 2.60291258397708e-07 74.8688226271867 17.2373466094825 4.34340762086899 2.52479965993284e-05 -24.2017885460264 26.5660536006388 -0.911004280494427 0.363707707594884 HABP4 other 0.002498796080618 1 0.246445694806045 4.34340762086899 -0.911004280494427 4.90880900553734e-05 56.8688861487876 22.7876805697692 2.49559782860181 0.0136284687891977 -68.7152804847326 35.0971429135697 -1.95785966549901 0.0520538437113929 SLC35D2 other 0.374051246221945 1 1 2.49559782860181 -1.95785966549901 1.88914455402596e-09 28.438852748422 5.62210863235691 5.05839616558597 1.20335744193947e-06 -8.60467703320355 10.6492077606441 -0.808011002001815 0.420346995265026 POLN other 2.10186223080929e-05 1 0.0130841054662078 5.05839616558597 -0.808011002001815 1.57855123778051e-19 212.210002803869 25.1865174527518 8.42553970400871 2.29355137280082e-14 -38.2020836254032 51.728267846682 -0.738514650029087 0.461318531931454 PPIL4 essential 2.22465225940407e-15 1 3.17725671674098e-10 8.42553970400871 -0.738514650029087 0.452293775947275 -2.75763712530286 3.14240172433319 -0.877557157618994 0.381551081697909 -8.07499687055769 6.51160248553337 -1.2400936464561 0.216826939263852 ULBP2 other 1 1 1 -0.877557157618994 -1.2400936464561 0.246908788783751 5.59762406591301 173.091636908599 0.0323390786862153 0.974243793989031 -488.848666853362 346.782878103242 -1.40966782883619 0.160667248394184 AKAP12 other 1 1 1 0.0323390786862153 -1.40966782883619 0.117273978988848 16.698361853863 33.7459297034746 0.494825953843663 0.62142820119258 -93.6176041232481 66.0134651821031 -1.41815921744143 0.158164673601073 SYNE1 other 1 1 1 0.494825953843663 -1.41815921744143 6.22881433569558e-05 4.26344920530089 3.16329447460796 1.34778764339645 0.179693288929169 -18.9472860212747 6.51473795761236 -2.90837269964713 0.00416718384413759 ULBP3 other 0.468655990617736 1 1 1.34778764339645 -2.90837269964713 2.19190092365205e-19 258.046343874235 31.4134060335095 8.21452928724031 8.09066290814596e-14 -70.9541903176807 63.964871960082 -1.10926807391971 0.269043779480173 LATS1 other 3.08597731040972e-15 1 1.11327521616088e-09 8.21452928724031 -1.10926807391971 7.16796324040332e-09 354.57352311644 140.641790802499 2.52111069613982 0.0127226383022577 -1005.77825507113 277.447131885957 -3.62511678615783 0.000392698963394781 EPS8L1 other 7.70986126137781e-05 1 1 2.52111069613982 -3.62511678615783 0.333205626887853 16.4609514153399 11.6093195751051 1.41790837170497 0.158211927033749 28.4108431754036 24.6036717267593 1.15473997096553 0.249962708267519 LILRB2 other 1 1 1 1.41790837170497 1.15473997096553 0.830029621973325 22.2298095863354 112.347629355137 0.197866298683223 0.843405631906662 262.296053111494 441.43958720567 0.594183350822336 0.553244711468944 C1QL1 other 1 1 1 0.197866298683223 0.594183350822336 0.000169814339929752 117.493023637557 27.808585124207 4.22506298370719 4.03694179154832e-05 -32.9947016123149 109.266305025442 -0.301965931808825 0.763077667652632 GFAP other 1 1 0.38520498574954 4.22506298370719 -0.301965931808825 0.653452921521251 -937.49523450033 1039.50710848517 -0.901865150173438 0.36851882890656 485.96769525966 4431.29008728216 0.109667317121574 0.912814169340628 PYY other 1 1 1 -0.901865150173438 0.109667317121574 0.764504466531101 0.759962255933795 1.27735815181878 0.594948452672975 0.552734438874936 2.44080714233862 5.03252236491412 0.485006715390975 0.628347621367709 HIGD1B other 1 1 1 0.594948452672975 0.485006715390975 3.80599741918505e-10 524.52729426392 131.392419361442 3.99206664138682 0.000105275057445376 -545.304134883565 196.782279580054 -2.77110386182779 0.00634616961789627 ATP6V1E1 essential 4.39097922251379e-06 1 0.960740174246502 3.99206664138682 -2.77110386182779 2.55298795268766e-16 37.5697153802245 5.00616530320875 7.50468933899243 4.40459058159816e-12 -66.9868893428006 21.9134431653685 -3.05688562209452 0.00263202044138517 ZNF227 other 3.49452990963888e-12 1 5.91536515108633e-08 7.50468933899243 -3.05688562209452 4.71767790715009e-18 226.068494150561 27.1571395430803 8.32445898037018 4.27313656458513e-14 -95.6717361548491 77.2260203557445 -1.23885363656102 0.217284612490725 ZNF428 other 6.57974537710223e-14 1 5.89692845912747e-10 8.32445898037018 -1.23885363656102 6.9357614233313e-15 121.232828702399 14.0547531362988 8.62575297671324 2.20350706425681e-14 58.1884688988117 25.6273574139048 2.27056063405273 0.0248578314230743 ZNF141 other 9.28074236055962e-11 1 3.05317938823424e-10 8.62575297671324 2.27056063405273 0.21715149908931 5.42517553601175 3.151625910838 1.72138943183432 0.0871882960115573 11.8710370058572 10.1979495377818 1.16406116365617 0.246199474732547 CCL25 other 1 1 1 1.72138943183432 1.16406116365617 5.7461113672319e-05 1285.31443379013 419.763924524261 3.06199356042053 0.00259807063002374 -552.371074187657 771.64503788184 -0.715835710813241 0.475183874168448 COX4I1 other 0.434406019362732 1 1 3.06199356042053 -0.715835710813241 6.39994776737492e-14 254.2731763757 36.1663708921178 7.03065223586248 6.273827499922e-11 34.8656178286458 66.4818811678475 0.524437895200651 0.600728061194961 EMC8 other 8.39609147601915e-10 1 8.22310570414777e-07 7.03065223586248 0.524437895200651 4.59298719043445e-13 846.928098201258 116.35806780688 7.27863666150683 1.61614617178372e-11 323.477585797911 213.065013274287 1.51821071337266 0.131011529478628 GSE1 other 5.89188396788932e-09 1 2.14575727227725e-07 7.27863666150683 1.51821071337266 0.13745722328891 43.7927720981516 32.7510918659063 1.33713930141485 0.183148902064326 -18.6921202038861 60.2762419224192 -0.310107591444479 0.756898399512087 GINS2 essential 1 1 1 1.33713930141485 -0.310107591444479 1.10183775961659e-13 938.1657223169 123.004863240793 7.62706203315194 3.63339331267702e-12 288.947064769113 217.00272667101 1.33153656270492 0.185223794535394 CHMP1A essential 1.43558441700445e-09 1 4.88546064822552e-08 7.62706203315194 1.33153656270492 0.0747796879362748 16.2540827714877 16.4848454414747 0.986001526625997 0.325699279196549 -36.7815925159033 26.7565000308775 -1.37467876865273 0.171254233419062 F12 other 1 1 1 0.986001526625997 -1.37467876865273 0.00305802478281822 177.337857797943 61.0837305945524 2.90319297907712 0.00424407404296264 -33.8526282762951 98.8073733925245 -0.342612369036584 0.732363418381787 PRR7 other 1 1 1 2.90319297907712 -0.342612369036584 0.0521906020977442 83.092926734689 37.592052035507 2.21038550000423 0.0290579053726376 55.166476818303 68.8079080263652 0.801746171343632 0.424353370286189 NFATC1 other 1 1 1 2.21038550000423 0.801746171343632 0.630586238996438 -130.864077467396 138.309319379707 -0.946169629453015 0.345790885037093 -124.512228995347 377.654410646883 -0.329698860876721 0.742150130032091 IDO1 other 1 1 1 -0.946169629453015 -0.329698860876721 1.74266132593263e-05 3.23074131204066 0.846389272846549 3.81708678936246 0.000196095388637415 -7.98411114135639 4.3593384281976 -1.83149605676691 0.0689842919876823 GJA9 other 0.140266810124318 1 1 3.81708678936246 -1.83149605676691 1.49621647667437e-20 1189.53277009729 116.26318754132 10.2313792977207 5.40946813220091e-19 -2090.61054360812 857.060495647593 -2.439280020751 0.0158754376067723 CAP1 essential 2.11998912579992e-16 1 7.72039291827713e-15 10.2313792977207 -2.439280020751 1.01118020624612e-30 1552.77308414405 106.109000267548 14.6337547260725 9.37770588953793e-31 -367.848974512145 782.206597678687 -0.470270866550846 0.638840029210202 PPT1 other 1.4663124170775e-26 1 1.36154911810201e-26 14.6337547260725 -0.470270866550846 3.82777553562588e-05 245.820422560051 57.29917753353 4.29012130961572 3.2580586278001e-05 21.0152939931571 100.332628886099 0.209456228013465 0.834388134631188 TRAF3 other 0.295351160328893 1 0.314402657582709 4.29012130961572 0.209456228013465 8.79979426171793e-17 61.1760925059029 6.64687248617279 9.20374095232983 2.34823109139199e-16 -16.658645403668 44.235786256653 -0.376587528183984 0.706998514398724 HAUS8 essential 1.21146767601071e-12 1 3.30630937667992e-12 9.20374095232983 -0.376587528183984 1.39962971463621e-07 154.152254743064 57.8160969952337 2.66625148971527 0.00847319801747421 -363.842888740584 110.468502149967 -3.29363467105446 0.00122218520542761 MRPS25 essential 0.0013769557132591 1 1 2.66625148971527 -3.29363467105446 3.79364484108289e-05 227.817547630679 103.33363825871 2.20467943904487 0.0289500232862336 -491.710802149487 197.913817908689 -2.48446928741654 0.0140375090345799 SH3BP5 other 0.293021127525242 1 1 2.20467943904487 -2.48446928741654 2.27488020677535e-07 72.0863762036419 15.8482741630759 4.54853162318409 1.07469001557966e-05 -27.9900295547715 30.281101621255 -0.924339870618334 0.356727893225353 HACL1 other 0.00219525939953821 1 0.108844604777908 4.54853162318409 -0.924339870618334 1.13095830621477e-12 570.876497170183 83.1098036560226 6.86894291716708 1.40374293792851e-10 -94.2665482728299 163.574873793855 -0.576289903739306 0.565239271600596 TBC1D5 other 1.43360274895784e-08 1 1.82121608766845e-06 6.86894291716708 -0.576289903739306 1.10082658166455e-07 227.369223253542 46.2242281491005 4.91883223058136 2.20102713314422e-06 -44.752457254519 88.5327723578882 -0.505490295431052 0.613932573865767 CAPN7 other 0.00109124939040406 1 0.0235399851889775 4.91883223058136 -0.505490295431052 0.127101664701742 -83.4133276194559 59.2997728578264 -1.40663823147253 0.161498546899028 -222.393668309407 112.664791225516 -1.97394115668533 0.0501320335763708 RFTN1 other 1 1 1 -1.40663823147253 -1.97394115668533 3.990964424712e-10 190.839069501382 33.7170807372324 5.6600116418337 7.00946220671524e-08 -58.2470531032508 64.422809554554 -0.904137113950713 0.367307946291831 RBSN other 4.59958649948059e-06 1 0.000820948213650489 5.6600116418337 -0.904137113950713 0.564590436523542 -4.0031690599967 5.25673436903696 -0.761531547718301 0.447474812772464 2.90104671576158 9.99240540771673 0.290325161699426 0.771948188973068 GALNT15 other 1 1 1 -0.761531547718301 0.290325161699426 0.00148113560302072 331.740055940448 111.562583231578 2.97357811491182 0.00341134680135467 -89.4981375642225 214.227451664306 -0.417771564143263 0.676688597832485 SLC6A6 other 1 1 1 2.97357811491182 -0.417771564143263 1.25881179565308e-05 339.534471376025 98.2465977092049 3.45594126710623 0.000706602623506969 -144.895178201272 176.654391941362 -0.820218374470798 0.413343129790711 KCNC3 other 0.102933040530552 1 1 3.45594126710623 -0.820218374470798 0.116260666403056 0.494105441856078 7.16218580396762 0.0689880792512195 0.945087458174467 -21.2643952634842 12.8781210512333 -1.65120324454846 0.100708745485686 NAPSA other 1 1 1 0.0689880792512195 -1.65120324454846 0.961261845870089 -6.26832028671129 26.5259899800374 -0.236308627554659 0.813503179040508 -12.4914426065686 47.6956224421719 -0.261899142247566 0.793744692615968 NAPSB other 1 1 1 -0.236308627554659 -0.261899142247566 2.52920369396324e-14 370.747241346789 73.2323609056682 5.0626148981371 1.15238402271244e-06 -374.323651876927 131.677009564364 -2.84274113693292 0.00507163002864675 NR1H2 other 3.34815985006853e-10 1 0.0125494620073384 5.0626148981371 -2.84274113693292 0.327587035060278 52.5336451602404 37.0568069567052 1.41765169410352 0.158299616996028 82.0223209199369 66.7757739029128 1.22832452738311 0.221187008750228 LRRC4B other 1 1 1 1.41765169410352 1.22832452738311 0.00957229982814505 156.042591355683 136.293762499272 1.14489899239899 0.254027224476097 -385.210301215204 213.950787970962 -1.80046217575738 0.0737447642972165 PDLIM4 other 1 1 1 1.14489899239899 -1.80046217575738 5.54517153341742e-06 69.4442036836403 20.2404080263903 3.4309685651147 0.000774666449554476 -41.7157951759138 31.1447156511286 -1.33941807795577 0.182433920307316 KIF3A other 0.0469287866873117 1 1 3.4309685651147 -1.33941807795577 0.00621169871580981 745.660491320676 230.84508204711 3.23013375337363 0.00152671873020232 666.838057050045 382.176652141861 1.74484247876691 0.083102145758278 MGAT1 other 1 1 1 3.23013375337363 1.74484247876691 0.0907253720703746 39.5939119357344 27.0241519477171 1.46513059918904 0.145006433692233 94.3123370015879 43.8577474409655 2.15041452205307 0.0331465866984015 GFPT2 other 1 1 1 1.46513059918904 2.15041452205307 4.25940225835046e-10 427.681743273743 61.5444611507533 6.94915082977387 9.41308307055805e-11 -100.097606849854 245.250617788142 -0.408144157811347 0.683727483924515 TUBG1 essential 4.90172011890971e-06 1 1.22756016323147e-06 6.94915082977387 -0.408144157811347 6.60768626117135e-11 780.006844626968 119.668534691964 6.51806129852569 9.61971160534846e-10 -1313.34934976044 475.67301740385 -2.761033949179 0.00646245635477124 PSME3 other 7.88098740369907e-07 1 1.21487337863946e-05 6.51806129852569 -2.761033949179 0.000519508346102557 4976.356152513 1911.17105394958 2.60382561897271 0.0101092135407778 -20593.4870017331 7583.81972199441 -2.71545049284444 0.00736491233346604 RPL27 essential 1 1 1 2.60382561897271 -2.71545049284444 3.61821364242912e-09 85.0677820370436 13.4075378122202 6.34477286049561 2.30201574389196e-09 -66.8307061225949 53.428153727927 -1.25085187227165 0.212861297495111 PSMC3IP other 3.96194393845989e-05 1 2.87084383420766e-05 6.34477286049561 -1.25085187227165 0.454326800533046 20.8922655715264 17.9303617682418 1.16518929409058 0.245744013306488 43.0960985626313 71.2717783951856 0.604672698409086 0.546286371995522 AOC3 other 1 1 1 1.16518929409058 0.604672698409086 8.97807122249558e-12 811.3879113499 107.306004929069 7.56143993885748 3.35391468044792e-12 -394.917734497423 430.550520502947 -0.917239013057284 0.360451632714706 ACLY other 1.10591881318701e-07 1 4.5143691598829e-08 7.56143993885748 -0.917239013057284 2.17632150817736e-10 381.546277173913 66.0365522271365 5.77780432663357 4.0251523851e-08 -943.662663043476 262.548251458701 -3.59424470664172 0.000436590471825209 VPS25 essential 2.53780851068562e-06 1 0.000477020809158201 5.77780432663357 -3.59424470664172 0.0188291690567231 98.0983695652174 34.9504643663931 2.8067830097143 0.00564673953346772 115.509782608695 138.956123504209 0.831268026883293 0.407100950484373 RAMP2 other 1 1 1 2.8067830097143 0.831268026883293 0.000577397568500739 9.46543463381246 2.58074074848679 3.66772006810931 0.000336535135903711 -10.9557837097879 10.258241584805 -1.06799821579715 0.287192609235183 AOC2 other 1 1 1 3.66772006810931 -1.06799821579715 0.00184412768075946 345.587235256364 158.929494675678 2.1744688483506 0.0312917671471347 -349.224317193183 234.283688300796 -1.49060448777302 0.138237529368206 NDUFA2 other 1 1 1 2.1744688483506 -1.49060448777302 1.42075171483523e-05 744.806477310631 185.69123532921 4.01099425069887 9.56233215497942e-05 -162.270766610211 272.588424089351 -0.595295882986656 0.552554862974762 ANKHD1 other 0.11545028434751 1 0.876865858611613 4.01099425069887 -0.595295882986656 0.00017459110143495 1030.0212514758 301.966054135263 3.41104980963989 0.00084007141703872 -264.181863590953 458.719365818547 -0.575911730082601 0.565573815552445 DIAPH1 other 1 1 1 3.41104980963989 -0.575911730082601 2.29918121070371e-05 457.894454101828 192.090914381064 2.38373821883877 0.0183401575456204 -719.189394098059 289.727310725227 -2.48229755178354 0.0141130550150354 NDFIP1 other 0.182968840747801 1 1 2.38373821883877 -2.48229755178354 2.71627445902978e-05 490.617014934641 179.561069748342 2.7323128316302 0.00703951981256832 -524.165448504984 262.250273030967 -1.99872222227616 0.0474332549525079 UBE2D2 other 0.214449868540401 1 1 2.7323128316302 -1.99872222227616 1.93453416475072e-15 436.982778522587 48.5332755059007 9.00377676898109 7.77506159337807e-16 -46.6494572672358 179.86009555384 -0.259365242321199 0.795699834188166 EXOC4 essential 2.61471637707707e-11 1 1.09146314647841e-11 9.00377676898109 -0.259365242321199 0.0016347222049479 54.0406553558664 61.6608730014439 0.87641729228519 0.382511661478294 -349.926518620471 136.132137575947 -2.57049161830173 0.0113474939867897 ACAP3 other 1 1 1 0.87641729228519 -2.57049161830173 1.29392510624978e-08 106.348690793863 31.7325893829456 3.35140285939032 0.00106845510393678 -208.687520847231 70.6625391073853 -2.95329779375873 0.00376746841379595 C1orf159 other 0.000137117243509289 1 1 3.35140285939032 -2.95329779375873 0.286452460761478 267.126751371184 195.653219100438 1.36530721344307 0.17414758992345 -312.653762964016 657.828114540109 -0.475281849549094 0.635259507720727 ANO1 other 1 1 1 1.36530721344307 -0.475281849549094 3.3910674033276e-07 327.051529743502 61.5490561551124 5.31367254307338 3.70481611727157e-07 -181.222510427692 206.941136713198 -0.875720087876247 0.382546070336248 PPFIA1 other 0.00322185313990155 1 0.00415939705486079 5.31367254307338 -0.875720087876247 0.877497049008761 3.26104186617607 11.060697955476 0.294831472598125 0.768565695533442 12.4459132825899 24.4010557404727 0.510056344076396 0.610826799866906 TMEM204 other 1 1 1 0.294831472598125 0.510056344076396 0.00071221431878465 227.189883045227 60.4299687557956 3.75955652009896 0.000243889850275988 135.393739950763 129.49671918613 1.04553799356227 0.297467593148369 KREMEN2 other 1 1 1 3.75955652009896 1.04553799356227 1.33173662413074e-11 303.352752406813 43.215433046558 7.01954674571922 7.32332953278567e-11 81.2568501604543 92.6073091374949 0.877434523443625 0.381663247582157 THOC6 other 1.6297792806112e-07 1 9.57818269593038e-07 7.01954674571922 0.877434523443625 5.81383449444238e-16 1436.91852361039 178.111310162579 8.06753104167717 3.11774432647079e-13 12.7182919300105 375.822781521315 0.0338411947208931 0.973052684845738 TRAF7 other 7.92134949867774e-12 1 4.26320359201616e-09 8.06753104167717 0.0338411947208931 0.196475232648799 59.7309018036072 66.9138886632885 0.892653274183089 0.373409046269573 187.4774749499 103.558453316074 1.81035414248312 0.0721530692482555 BARX1 other 1 1 1 0.892653274183089 1.81035414248312 0.000108539689283835 251.0989195231 105.869559284142 2.37177637482346 0.0189551983649214 -292.246739940387 157.196522339517 -1.8591170821781 0.0649438615904282 NINJ1 other 0.793208049286263 1 1 2.37177637482346 -1.8591170821781 7.86742370127497e-12 144.429268927804 26.4114504041451 5.46843383145428 1.93628917710393e-07 -91.7578282663891 60.1976321055195 -1.52427637196008 0.129617784623088 NPHP4 other 9.70604062026293e-08 1 0.00221259764267666 5.46843383145428 -1.52427637196008 5.23989559409818e-06 1285.97507045306 282.001680596492 4.56016810868985 1.09985654466609e-05 568.819856926077 402.709291401334 1.41248257507722 0.160011314009309 MAP1B other 0.0444657540115172 1 0.111272486623868 4.56016810868985 1.41248257507722 0.00202647165495578 14.7130541474279 37.9893307701314 0.387294375793424 0.699069560225031 -122.168334893934 53.404277505263 -2.2876132886901 0.0235124496601877 CKMT2 other 1 1 1 0.387294375793424 -2.2876132886901 3.08409674925165e-08 17.2703335378256 28.8161174165455 0.599328954979529 0.549828561615164 -162.773643085467 40.5088455084705 -4.01822468752981 9.12177320514945e-05 ZCCHC9 essential 0.000318556353230203 1 1 0.599328954979529 -4.01822468752981 0.0284206479680772 -21.0830047526846 30.5041501043125 -0.691152013106047 0.490517341527093 -337.475699700759 125.317037506469 -2.69297540394967 0.0078715809892299 TNS4 other 1 1 1 -0.691152013106047 -2.69297540394967 3.28207204850483e-06 1093.88740682961 211.858194811872 5.16329995070981 7.34719071333972e-07 1581.07151152712 870.787173010106 1.81568075476093 0.0713520469948487 TOP2A essential 0.0284424363723429 1 0.00808925697538703 5.16329995070981 1.81568075476093 7.53208441304912e-25 395.561583333333 30.8780395734733 12.8104500414318 6.75981023493398e-26 239.242154761904 188.089989195481 1.27195581107329 0.205344244215695 STARD3 other 1.08439419294668e-20 1 9.77671354278501e-22 12.8104500414318 1.27195581107329 0.0438302839551984 156.289145907474 84.5270725428969 1.84898330446921 0.0663774790010298 -463.217793594297 344.251139623079 -1.34558100258281 0.180415478387904 RARA og 1 1 1 1.84898330446921 -1.34558100258281 6.82672278651526e-06 685.084083333333 237.390870838159 2.88589060276201 0.00447534409895785 -5539.97058333332 1446.03889844787 -3.8311352407461 0.000186602735287768 PPP1R1B other 0.0572420705649305 1 1 2.88589060276201 -3.8311352407461 0.128087596729733 35.8653788688382 26.9830783630878 1.32918039914605 0.185833820971428 -214.121098241011 168.78400326104 -1.26861014138794 0.20657186986856 KHDRBS3 other 1 1 1 1.32918039914605 -1.26861014138794 0.0563080724186807 19.573473233841 22.8438421988084 0.856838051300408 0.392938600300339 -78.0361737890288 47.3128778039649 -1.64936434668722 0.1012229747508 CLUHP3 other 1 1 1 0.856838051300408 -1.64936434668722 1.33522843506537e-06 438.983849616096 186.947884956894 2.34816162652664 0.0202559743164698 -497.5303591916 265.588009248518 -1.87331634662033 0.0630947216792985 MCCC2 other 0.0120437604842896 1 1 2.34816162652664 -1.87331634662033 9.26052249339513e-13 109.179548317437 18.3278509664429 5.95702946937631 1.64576159794543e-08 -50.1363385519764 36.3861383835836 -1.37789666008077 0.170208503520386 ZNF304 other 1.17710501413546e-08 1 0.000198363645400363 5.95702946937631 -1.37789666008077 2.53257663951009e-08 27.0972463125355 7.60433730088893 3.56339352666114 0.000486000962857119 -35.8576434477519 15.4236640141464 -2.32484599086596 0.0213691665916669 ZSCAN5A other 0.000263058735545913 1 1 3.56339352666114 -2.32484599086596 0.00946628571538598 21.3878525746146 9.12647686261298 2.3434949648786 0.0205215782632292 -2.64758937356521 16.1042530450931 -0.164403115509411 0.869652640068371 ZNF132 other 1 1 1 2.3434949648786 -0.164403115509411 2.09377829861672e-06 210.402714667428 53.1309123747426 3.96008096347785 0.000114795925346408 -225.354078453166 98.3272765802254 -2.29187755718322 0.0232856222264739 SELENOS other 0.0185383130559525 1 1 3.96008096347785 -2.29187755718322 3.67119693548435e-06 302.743940689558 60.1507527673694 5.03308648289752 1.34779004458726e-06 15.4588197442244 111.318617345587 0.138870030124725 0.88973667191162 CHSY1 other 0.031675087159359 1 0.0146073485032367 5.03308648289752 0.138870030124725 3.96222602743075e-05 139.642965659749 38.8248146436747 3.59674519869213 0.000435134833632346 -129.027454650877 71.8515477528177 -1.79575052571943 0.0745206208418077 SNRPA1 essential 0.305051781851893 1 1 3.59674519869213 -1.79575052571943 2.80659164208171e-11 581.346199175015 77.4348286586609 7.50755453644299 5.22419037490494e-12 648.864957768612 239.267594190503 2.71187980956582 0.00748262813676363 LLGL1 other 3.39541456859045e-07 1 7.00720654985999e-08 7.50755453644299 2.71187980956582 1.33543626791491e-05 43.2727776133177 9.9723726032344 4.33926602374271 3.27464207947254e-05 -7.34817420377171 28.2331884679634 -0.260267245837635 0.79516253538893 THAP1 essential 0.108914985084532 1 0.315843842064861 4.33926602374271 -0.260267245837635 3.12591609886911e-17 452.92859526699 52.4204895166855 8.64029694195859 7.4828104535856e-15 -458.188273665048 254.417498599813 -1.80093065998482 0.0737094248346445 RHPN2 other 4.32376714795575e-13 1 1.04250515239355e-10 8.64029694195859 -1.80093065998482 3.09396481960303e-05 161.635207759972 34.1823466323858 4.72861648435897 5.91377057451184e-06 145.07742029997 153.305880850281 0.946326517256389 0.345779129594303 C19orf12 other 0.242102747133937 1 0.0612607493813681 4.72861648435897 0.946326517256389 4.22431846510355e-20 48.3708662997843 4.7538305894003 10.1751346393449 8.08745359507121e-19 -15.7526554371645 23.0806808967149 -0.682503930783367 0.495973002070835 FAAP24 other 5.97191901411688e-16 1 1.15327088265715e-14 10.1751346393449 -0.682503930783367 5.46370408790969e-09 197.693543745204 58.516600461278 3.37841812728036 0.000919479172756832 -268.140947173189 82.0678664811136 -3.26730739655449 0.00133365228700228 ACTR10 essential 5.91609878638861e-05 1 1 3.37841812728036 -3.26730739655449 0.0853559967746937 3.92357508399583 2.32923038006714 1.68449420786051 0.0940731238124042 -2.30345726381976 3.78139255838262 -0.609155814493114 0.54330163191452 ABHD12B other 1 1 1 1.68449420786051 -0.609155814493114 0.435476227858534 16.9747217233067 16.976498787694 0.999895322091465 0.318899765621811 -6.24735016779313 24.9966937642153 -0.249927059423223 0.802970479181807 GCH1 other 1 1 1 0.999895322091465 -0.249927059423223 0.00100458597145364 -683.287605068369 450.840558623534 -1.51558592499868 0.131634858232396 -2643.77595868356 698.093382825547 -3.78713797283513 0.000216596937777433 LGALS3 other 1 1 1 -1.51558592499868 -3.78713797283513 0.911999687340906 5.62692367634144 13.1245371571194 0.428733113326523 0.668732523320944 9.95131167860783 95.3310761458008 0.104386859783143 0.9170017965363 PODNL1 other 1 1 1 0.428733113326523 0.104386859783143 3.56248343141788e-28 2618.96820536461 190.480041169281 13.7493051203045 1.83134077753167e-28 1580.67710947104 1328.80916888 1.1895441019596 0.236080441871131 DNAJB1 other 5.15491352526167e-24 1 2.65489472518767e-24 13.7493051203045 1.1895441019596 3.29318118030832e-24 434.797414650717 37.3669819422476 11.6358718861137 1.04838339058972e-22 -272.766542486944 264.465929556302 -1.0313863224067 0.304019803902803 ZSWIM4 other 4.73164271986699e-20 1 1.50998659746637e-18 11.6358718861137 -1.0313863224067 4.24608499790354e-06 76.9351178547166 22.6965673501584 3.38972482789032 0.000897007496509502 -254.468153436879 110.707978765082 -2.29855297039476 0.0229303802384166 FBXW9 other 0.0364144249420208 1 1 3.38972482789032 -2.29855297039476 2.06395975544185e-18 176.116686451207 18.8654012340799 9.33543285223408 1.27593359356457e-16 -222.969011729441 137.030280004319 -1.62715139838008 0.105803776174243 RFX1 other 2.88830528176533e-14 1 1.79970433372283e-12 9.33543285223408 -1.62715139838008 3.93214957010946e-15 51.0611120494485 7.39403721971017 6.90571477153722 1.32299292678987e-10 -80.3426254235025 31.807743021081 -2.52588262456265 0.012578780265793 ZNF20 other 5.28441580727011e-11 1 1.7175094175586e-06 6.90571477153722 -2.52588262456265 1.26320274497174e-10 43.2302113514763 7.09262134741511 6.09509647194566 8.83066289739184e-09 -102.851004926089 50.8440511072736 -2.02287195229759 0.0448628992206082 C19orf57 other 1.48918971604719e-06 1 0.000107742476848214 6.09509647194566 -2.02287195229759 3.1858580884593e-29 425.838568346969 31.4869881557392 13.5242712399392 9.41100384228325e-28 -220.935434912747 228.708138774131 -0.966014747428555 0.335591690287621 DCAF15 other 4.61344109789791e-25 1 1.36393678686211e-23 13.5242712399392 -0.966014747428555 1.84169256633958e-15 308.376795009044 37.790306777519 8.16020882880193 1.21283646139688e-13 -481.94264824975 274.731273032167 -1.75423293799291 0.0814192182982448 CC2D1A other 2.49033668820438e-11 1 1.66631601431317e-09 8.16020882880193 -1.75423293799291 0.428599482638836 13.1185326268799 12.2523433478348 1.07069580523942 0.286049209491137 -16.7783235150094 60.5521697220709 -0.277088725177321 0.782098612465271 RTBDN other 1 1 1 1.07069580523942 -0.277088725177321 0.942556944817778 3.05421390097423 10.1810250340277 0.299990805519704 0.764602278911398 8.22411272267604 33.9006414492248 0.242594605031113 0.808653077088528 MATN3 other 1 1 1 0.299990805519704 0.242594605031113 5.80297512664657e-06 -9.14407480966594 40.2861167630805 -0.226978312738394 0.820739692037083 -259.767841774247 63.2125854231054 -4.10943232325532 6.4079511458843e-05 TRIM21 other 0.0490177308947836 0.920950738686492 1 -0.226978312738394 -4.10943232325532 0.000773250689975375 29.2123720226278 17.0956430567411 1.70876122797316 0.0894839389849236 -150.311336665751 53.6198858034147 -2.80327595655152 0.00570120146277998 SPATA6 other 1 1 1 1.70876122797316 -2.80327595655152 7.13283374116354e-06 595.70923444929 181.355691288354 3.28475621700847 0.00126038810096044 -1672.33981054006 610.259830227753 -2.74037340769412 0.00685293957775919 LRRC41 other 0.05970895124728 1 1 3.28475621700847 -2.74037340769412 0.0054147232534497 12.177913562735 3.71069685513364 3.28184005273489 0.00127939099551364 4.49737633043352 14.3223685967079 0.314010654038556 0.753943495169651 CCT6B other 1 1 1 3.28184005273489 0.314010654038556 6.69828319513171e-15 706.530442804429 97.5152415961189 7.24533346008292 3.90947052145499e-11 -494.179793204182 220.506980187368 -2.24110725558108 0.0267838848476058 DHX30 other 8.96699171332282e-11 1 5.15307309432982e-07 7.24533346008292 -2.24110725558108 6.03234962996563e-10 410.226373626374 86.8978740133507 4.72078722620243 5.16810697462883e-06 -371.871428571429 168.989403953586 -2.2005606261181 0.0292275210717621 RAF1 og 6.88773680749475e-06 1 0.0537896573919369 4.72078722620243 -2.2005606261181 0.54060408937682 -16.4069002988317 33.4407254437105 -0.490626327064849 0.624375786433404 40.5917413746266 65.0563809398996 0.623947117687442 0.533567847270029 SLC6A11 other 1 1 1 -0.490626327064849 0.623947117687442 0.444519413760631 -7.98373590982287 7.48398095181982 -1.06677662078784 0.287700045888967 -16.517230273752 14.5416678545225 -1.13585528420766 0.257737112535673 PPARG other 1 1 1 -1.06677662078784 -1.13585528420766 0.0126465481039007 516.774932871437 224.64888200127 2.30036725875411 0.0227523695880307 -233.297684411553 439.904467863888 -0.530337156029382 0.596632281275504 NUP210 other 1 1 1 2.30036725875411 -0.530337156029382 1.02745468705395e-11 233.186865871334 48.4542992409521 4.81251136688098 3.78886852455088e-06 -347.16582116178 128.079346012848 -2.71055273132762 0.00755163867221967 ENOSF1 other 1.2625363194519e-07 1 0.0398664746153243 4.81251136688098 -2.71055273132762 0.0225245238105689 122.214395935084 64.0200052152834 1.90900321741786 0.0581841376767015 -136.865316021228 170.705789564705 -0.801761418697227 0.423967789707734 EMILIN2 other 1 1 1 1.90900321741786 -0.801761418697227 8.53027605842722e-11 34.6675746276994 69.3175301517073 0.500127089811574 0.617694896676977 -582.538050637432 109.887010259597 -5.30124579111982 3.89669364476165e-07 ARFIP2 other 1.01297028193823e-06 0.00568995206008097 1 0.500127089811574 -5.30124579111982 1.43584630659223e-07 15.1730344639065 37.7363153422166 0.402080444958864 0.688175181281762 -260.34029690687 60.2621334270422 -4.32013077037933 2.76491000962218e-05 TRIM5 other 0.00141071899622686 0.399557145490501 1 0.402080444958864 -4.32013077037933 0.00264881054919519 -25.7179805286289 135.060894431032 -0.190417667800665 0.849229423747644 -612.602571650861 215.682362391993 -2.8402998041049 0.00510865387567327 TRIM22 other 1 1 1 -0.190417667800665 -2.8402998041049 2.62529824490243e-15 6.45018359853117 14.7060283679927 0.438608129749691 0.661616813480379 -157.631534438634 23.732726426934 -6.64194798368127 6.22298676353174e-10 RRP8 other 3.53863950430399e-11 9.10236273901788e-06 1 0.438608129749691 -6.64194798368127 4.26333306210583e-13 133.729576458506 40.1813339986157 3.32815173491036 0.00109213826141413 -234.958131460849 63.6982687018234 -3.68861095049077 0.000311527352970326 TIMM10B other 5.47411965174388e-09 1 1 3.32815173491036 -3.68861095049077 1.80503672172483e-05 293.683949564749 62.0389954175733 4.73386049512916 5.10568953764651e-06 -15.3726255646294 404.562861597345 -0.037998113578526 0.969740392350732 EFR3A other 0.145106902059459 1 0.0531706508450507 4.73386049512916 -0.037998113578526 2.10953953872093e-06 136.8001998002 30.4004356285442 4.4999420887164 1.31165536161943e-05 -30.8934494077353 66.5095569744966 -0.464496394399102 0.642931562588693 IQCA1 other 0.0186736439967576 1 0.131677081752974 4.4999420887164 -0.464496394399102 0.00399612710382668 33.6918433000605 21.9228136244563 1.53683938007278 0.126527029254114 -93.5398021264923 48.2512700894263 -1.93859771883995 0.0545062963256813 ILKAP other 1 1 1 1.53683938007278 -1.93859771883995 0.0537946963993872 48.1414754515389 37.5633677323671 1.28160701123869 0.202012158211877 -105.381475451539 84.8934438029947 -1.2413382085911 0.216471522191947 PER2 other 1 1 1 1.28160701123869 -1.2413382085911 0.630204390984893 -44.79118993135 47.825532348205 -0.936553922813389 0.350483528190667 -28.260686883449 105.563732334229 -0.267712084998775 0.789286277986956 RAMP1 other 1 1 1 -0.936553922813389 -0.267712084998775 0.0047130988573227 52.4854412091575 33.7810575175345 1.5536944390185 0.122467720124092 -139.706601466993 77.9383137411695 -1.79252789495746 0.0751625095941562 SCLY other 1 1 1 1.5536944390185 -1.79252789495746 0.573195229363725 -18.8777932048843 20.1311422667321 -0.937740787619437 0.349827181460823 0.551365231945739 38.0746252707765 0.0144811729077982 0.988464603028413 PTPRE other 1 1 1 -0.937740787619437 0.0144811729077982 3.18146141527704e-09 740.633901429463 340.837860673794 2.17298013772684 0.031362017376431 -2770.39299776027 663.592666776519 -4.17483968172491 5.05253092732756e-05 RAN essential 3.49642609538947e-05 0.727008675133163 1 2.17298013772684 -4.17483968172491 2.12269279932203e-05 196.1320442902 41.9617368068764 4.67406878778333 6.55495910741882e-06 -57.9184845480084 168.333298478454 -0.344070276478434 0.731278525399154 PRKAA1 other 0.169412112313891 1 0.06762751311124 4.67406878778333 -0.344070276478434 0.757740648563165 -2.28359214351555 13.9559092985829 -0.163629047356121 0.870240542099595 -44.4761752818549 59.7423362027655 -0.744466622980774 0.457743643946824 CARD6 other 1 1 1 -0.163629047356121 -0.744466622980774 2.62160204375772e-18 324.564247013217 31.6320609594392 10.2606101900662 3.78503013489026e-19 88.6464487316058 185.977497665641 0.476651475819824 0.63428595252913 RAP1GAP2 other 3.66604829799079e-14 1 5.40540153563679e-15 10.2606101900662 0.476651475819824 4.09590923541005e-21 1321.31763637617 118.473701539115 11.1528349263227 1.75882013803727e-21 -416.670111031934 696.585769919562 -0.598160526707356 0.550623063834992 CLUH other 5.82274456905893e-17 1 2.52672101030434e-17 11.1528349263227 -0.598160526707356 1.11898627080575e-07 181.490373355845 32.8002235327131 5.53320538120225 1.46969615080731e-07 -149.244147308992 138.863128946121 -1.0747571975488 0.284306267055392 INPP5K other 0.00110880349574142 1 0.00169279602649985 5.53320538120225 -1.0747571975488 7.99939821967819e-22 781.591265804388 75.327277378822 10.3759394073644 1.65018270367992e-19 -1475.42302475416 426.086417028722 -3.46273189143858 0.000690258577391129 MYBBP1A essential 1.14071418612611e-17 1 2.35959624799192e-15 10.3759394073644 -3.46273189143858 2.70033240675707e-19 807.064608987688 75.644282813355 10.6692082860914 4.25583817823931e-20 379.266112266112 345.28625193284 1.098410695888 0.273796954329521 RPA1 essential 3.79963772954788e-15 1 6.09563702269216e-16 10.6692082860914 1.098410695888 0.0387183375862174 -304.55050335901 194.737591070048 -1.56390197539962 0.119962000672323 -2095.10883784156 894.797801070147 -2.34143270729531 0.0205344845394537 SERPINF1 other 1 1 1 -1.56390197539962 -2.34143270729531 8.79802859836136e-21 402.240747394897 36.9771748566035 10.8780821940772 7.27423313584384e-21 -206.609773625584 210.289450013786 -0.982501849769637 0.327373977867318 UBE2G1 other 1.24861621867944e-16 1 1.04407068198767e-16 10.8780821940772 -0.982501849769637 3.36254765135037e-06 127.943680051568 26.1372908958645 4.89506278830956 2.48451286335134e-06 -122.389632906187 106.832135009693 -1.14562563871893 0.253750576879962 EEFSEC essential 0.0291196626606942 1 0.0264724845590085 4.89506278830956 -1.14562563871893 1.55799638363584e-15 544.621350364963 77.8046362261986 6.99985729361429 7.55022947741033e-11 -129.806955362156 149.174752196806 -0.870167058772131 0.385572276847307 TBC1D14 other 2.1087481052511e-11 1 9.871925041714e-07 6.99985729361429 -0.870167058772131 2.41123225831079e-13 115.533129838842 30.2546583899123 3.81868895526394 0.000195392687650763 -219.407555025378 56.2930497384228 -3.89759581413515 0.000145674777518861 TMEM128 other 3.1157943241892e-09 1 1 3.81868895526394 -3.89759581413515 5.39756893898724e-14 41.621435433055 8.85618530593733 4.69970241082821 5.76428258574047e-06 -49.8087746286805 17.9164752731565 -2.78005432816949 0.00611759842936071 COQ3 other 7.09564412719263e-10 1 0.0597756104141286 4.69970241082821 -2.78005432816949 1.25347594550117e-11 800.842871873761 125.588318005372 6.37673061151679 2.03100881496826e-09 145.571371951015 254.071015500552 0.572955445800145 0.567515947366643 PNISR other 1.53550803323893e-07 1 2.53815171606583e-05 6.37673061151679 0.572955445800145 0.89460790589222 2.66878568575568 9.31750194286641 0.286427167079792 0.774935937132065 -2.44441400756298 19.2204607994291 -0.127177700528157 0.898965662274336 POPDC3 other 1 1 1 0.286427167079792 -0.127177700528157 0.785286333995975 -32.7984893660592 81.241947248683 -0.403713727659215 0.686986928334235 -143.566257390015 208.495064583243 -0.688583481230054 0.492128199134748 SEC61G essential 1 1 1 -0.403713727659215 -0.688583481230054 1.38579949796982e-05 185.440945659473 46.47887057238 3.98979027191919 0.000103091776421617 -88.068653139689 118.957779016981 -0.740335385104304 0.460253753571688 LANCL2 other 0.112804079134743 1 0.942155744717159 3.98979027191919 -0.740335385104304 0.000688393973311579 26.4037013603291 17.0469965369236 1.54887702963621 0.123477290254943 -101.021727301487 41.4129033898058 -2.43937804482345 0.0158559523202178 FIGNL1 other 1 1 1 1.54887702963621 -2.43937804482345 0.521062658981541 -47.0332173362861 47.2292854522455 -0.995848590253232 0.320896077142435 -110.7844985764 114.735861614504 -0.9655612205068 0.335787499397185 DDC other 1 1 1 -0.995848590253232 -0.9655612205068 1.79605803580086e-32 755.608881869425 59.6061323954193 12.6766970360837 1.12713859374978e-25 -349.673792027635 149.272356844576 -2.34252208124321 0.0204334309065659 GRSF1 essential 2.60805587378642e-28 1 1.62916612340594e-21 12.6766970360837 -2.34252208124321 0.225049936321921 55.1761634685463 32.118864032704 1.7178740634278 0.0878295501424588 81.2803790954509 80.9045577185213 1.00464524357499 0.316643650319785 ENAM other 1 1 1 1.7178740634278 1.00464524357499 0.274969161575634 481.428659177054 298.584376441102 1.6123705631062 0.108928792789028 510.844261434913 752.107449784991 0.679217127261471 0.498019862481422 JCHAIN other 1 1 1 1.6123705631062 0.679217127261471 1.58078557701058e-23 1350.45255949482 124.677922452379 10.8315292148907 1.3708738458824e-20 164.174509738061 269.6706142411 0.608796439315707 0.543574154809908 ANKRD17 other 2.26700459599087e-19 1 1.9665185319183e-16 10.8315292148907 0.608796439315707 1.53824102683016e-23 156.994828116065 17.3731035084077 9.03665991744581 6.38878697085711e-16 -142.448183908225 43.50767282133 -3.27409338792279 0.00130909892399606 UTP3 essential 2.20614528067982e-19 1 8.97305130056881e-12 9.03665991744581 -3.27409338792279 0.0116691909517526 1721.72638381148 673.529566444239 2.55627439326974 0.0115540849740309 -5165.81174320152 3094.6626013516 -1.6692649276032 0.0971097726002779 ITGB4 other 1 1 1 2.55627439326974 -1.6692649276032 1.53355998970885e-06 909.832845089086 168.477950615365 5.40030812201789 2.43686025126856e-07 103.589478607107 783.518832896582 0.132210579066937 0.894988105071638 WBP2 other 0.0137621673476473 1 0.00276729850134058 5.40030812201789 0.132210579066937 1.44250924288628e-16 432.886994265479 44.9912130939442 9.62158973934725 1.79306747591947e-17 123.455848154119 208.190674019704 0.59299413259229 0.554049301425463 UNK other 1.97955543401285e-12 1 2.54095592012549e-13 9.62158973934725 0.59299413259229 0.134686394703971 205.206439627678 105.6299692045 1.9426914650557 0.0538542251194892 248.144446681782 491.23977284695 0.505139160951232 0.614173990061333 TRIM47 other 1 1 1 1.9426914650557 0.505139160951232 1.46004929447115e-06 234.75598027127 82.7926513173944 2.83546880714459 0.00518264585527445 -888.018906699548 249.842947535954 -3.55430847841626 0.000501788788309619 ZRANB2 other 0.0131229230587067 1 1 2.83546880714459 -3.55430847841626 2.40277522621242e-06 1507.30190423369 324.273844553583 4.6482376841362 7.45890612915292e-06 -2351.77121464225 1721.49708041537 -1.36611978108892 0.174016369685136 EIF5A essential 0.0211396164402169 1 0.0765134590728506 4.6482376841362 -1.36611978108892 1.20991618714104e-10 559.733399202753 79.9762373756372 6.99874634729018 9.04089646656023e-11 -3.66590576130609 424.342434986923 -0.00863902701934362 0.993119096348216 KDM6B other 1.42758010920772e-06 1 1.17956576199211e-06 6.99874634729018 -0.00863902701934362 0.0809196676530339 -7.57336417713151 3.90624378120352 -1.93878431591337 0.0543442647979956 -33.6253029301607 21.1278272258989 -1.59151731839904 0.113530617681599 CLEC10A other 1 1 1 -1.93878431591337 -1.59151731839904 2.21339058733583e-08 9.8392386880536 1.99910034833425 4.92183331179555 2.16029565300113e-06 -32.4290825419626 10.8130967532321 -2.99905598572114 0.00315299471439758 SLC52A1 other 0.000230989441694367 1 0.0231151634871121 4.92183331179555 -2.99905598572114 4.02701886731707e-16 615.750046219265 68.8438074515437 8.94416025221537 1.60724747956315e-15 -391.26871880199 365.476326638879 -1.07057199135252 0.286140710002641 GPS2 other 5.4968807538878e-12 1 2.25014647138841e-11 8.94416025221537 -1.07057199135252 0.076634808205751 314.284867342219 139.477733944015 2.25329777345228 0.0256432115779212 133.853214480932 748.792445876786 0.178758767156363 0.858360563310625 XAF1 other 1 1 1 2.25329777345228 0.178758767156363 1.41704012134634e-07 128.079247935337 30.0365717047806 4.26411007202102 3.54806476029622e-05 -478.151379370935 160.947624466862 -2.97085080289199 0.003463105691947 DLG4 other 0.00139323384730772 1 0.34100450411207 4.26411007202102 -2.97085080289199 9.45255637836657e-05 58.0961576946169 15.9265371264328 3.64775828125227 0.000363641791903772 -93.8273271655299 70.5188129449043 -1.33052902122497 0.185349863822766 RIDA other 0.695424572756428 1 1 3.64775828125227 -1.33052902122497 6.17206563524895e-05 129.235750691229 30.3345985360602 4.26034155479592 3.57670972839753e-05 -21.9140829855378 131.207828879754 -0.167018105342029 0.86757925715811 VPS13B other 0.464571380365189 1 0.343471435218015 4.26034155479592 -0.167018105342029 0.583046678078667 -4.96481796529428 10.9803528768862 -0.452154682181964 0.651810736829559 -48.9249501774169 47.3455494126107 -1.03335901229157 0.303099095987389 RGS22 other 1 1 1 -0.452154682181964 -1.03335901229157 0.00391997828464601 426.883430058036 126.942737060762 3.36280310273839 0.0009777745474852 328.1501003166 562.071406887625 0.583822795992551 0.56021063286153 MATN2 other 1 1 1 3.36280310273839 0.583822795992551 2.20198504279714e-06 156.698463233203 33.6098008021531 4.66228479471276 6.76177073901905e-06 3.59498417233104 48.9059783412846 0.0735080719016368 0.941497834340384 REEP2 other 0.0194589418231984 1 0.0696665239241132 4.66228479471276 0.0735080719016368 1.526965300346e-07 32.3322510341144 13.8218649864369 2.33921045140012 0.0205842237939467 -78.672016634791 22.7053320537562 -3.46491372372492 0.000684018947873148 PCBD2 other 0.00149673138739914 1 1 2.33921045140012 -3.46491372372492 2.45643310837658e-09 232.216084283376 37.0058883956004 6.27511172819144 4.35481316710136e-09 -234.109185281304 148.951797768178 -1.5717110420222 0.118341200192492 SDF2 other 2.71583244462115e-05 1 5.37645233610334e-05 6.27511172819144 -1.5717110420222 1.56012117571019e-11 802.712781444098 113.543701500657 7.06963724834579 7.74123665429924e-11 -1013.78600543478 491.500159106989 -2.06263616938953 0.0410786592893291 FLOT2 other 1.90506396765971e-07 1 1.01177963071691e-06 7.06963724834579 -2.06263616938953 1.33075582543625e-16 457.097810075616 48.692122153356 9.38751054299884 2.24858550810112e-16 -327.611214769715 210.345112306645 -1.55749383086267 0.121729684406874 ERAL1 essential 1.82726082390651e-12 1 3.16668297105881e-12 9.38751054299884 -1.55749383086267 3.73206724960115e-21 189.648745519713 30.3932269092188 6.23983580572648 4.14854989736587e-09 -116.905017921147 48.9827162357397 -2.38665853805487 0.0182322534251494 PRMT7 other 5.30699962893284e-17 1 5.12677796316474e-05 6.23983580572648 -2.38665853805487 2.35518862077926e-12 200.577813486648 40.685780417112 4.92992420030579 2.14334441269609e-06 -76.6184704580874 65.4862411393697 -1.16999340815769 0.243846970165377 NIP7 essential 2.95670379452628e-08 1 0.0229466452823244 4.92992420030579 -1.16999340815769 1.71450402348018e-20 286.694828703777 38.2733919707828 7.49070866053978 5.21590426696905e-12 -50.2171833747017 61.2742310470533 -0.81954816105549 0.413756937656894 TERF2 essential 2.42825204845498e-16 1 6.99713557413898e-08 7.49070866053978 -0.81954816105549 7.30522623694563e-11 336.507370796439 77.5232938252108 4.34072591852393 2.58940290617286e-05 -159.942905966135 124.900992030488 -1.28055753093693 0.202312620882979 VPS4A other 8.69760235770746e-07 1 0.252596253497162 4.34072591852393 -1.28055753093693 0.000631535387201894 202.188422904227 137.400719839092 1.47152375286684 0.143216864579559 -348.799819469518 218.889256404 -1.59349903782278 0.11312563271525 MTSS1L other 1 1 1 1.47152375286684 -1.59349903782278 0.00461576542514029 39.0872258006396 11.9178181726734 3.27973000043444 0.0012992765970733 79.1324001921835 44.2067761831575 1.79005136824097 0.0755181666732043 HSPA12B other 1 1 1 3.27973000043444 1.79005136824097 4.15923932355749e-08 68.814039861497 14.4348408318416 4.76721847252385 4.33425959694722e-06 -94.0877700903365 46.4350201342471 -2.02622438449088 0.044490663004024 ANKEF1 other 0.000425531775193167 1 0.0454230405760068 4.76721847252385 -2.02622438449088 6.26979851676189e-11 324.833584640129 47.6846168244476 6.81212529894103 2.17803239193669e-10 -52.4952754322477 177.535752959045 -0.295688471517946 0.767876932733499 PCED1A other 7.48551244916202e-07 1 2.8072659499672e-06 6.81212529894103 -0.295688471517946 0.312730741955241 0.798397028764428 15.0701939120593 0.0529785504701133 0.957818561773174 -68.6780473755593 48.4788690007468 -1.41665943928068 0.158628738379344 SNAP25 other 1 1 1 0.0529785504701133 -1.41665943928068 2.0348097064903e-10 439.400223781039 64.8681377140062 6.77374500433924 2.53823603382656e-10 -19.9144640013769 214.826653498966 -0.0927001546457211 0.926263045793297 BTBD3 other 2.37726818009262e-06 1 3.26417153950096e-06 6.77374500433924 -0.0927001546457211 0.00218437261684413 495.435902663677 152.346743800895 3.25202817141383 0.00140791740639621 -119.266703445629 525.131988178802 -0.227117574496377 0.820633538387629 PCNA essential 1 1 1 3.25202817141383 -0.227117574496377 0.000119218172685731 132.989973496225 30.705445649389 4.33115268916057 2.6817841961902e-05 105.542164002471 112.548136881219 0.937751320698078 0.349859870496406 NXT1 other 0.866596897252578 1 0.261232598550888 4.33115268916057 0.937751320698078 8.59946606472427e-11 63.3795850697797 9.95855899864077 6.3643329399796 2.13621738455358e-09 -27.5041958597822 31.5578183934395 -0.871549342127527 0.38481097303336 POLR3F other 1.02101460586471e-06 1 2.66749464809205e-05 6.3643329399796 -0.871549342127527 6.19129961955634e-06 280.123894159361 61.3912646352596 4.56292757322472 1.02870522173651e-05 -55.9653832497337 202.878025961317 -0.275857293980199 0.783029914813559 RIN2 other 0.0521431253959035 1 0.104351857692951 4.56292757322472 -0.275857293980199 3.99079428031851e-16 804.735524728589 91.091573194513 8.83435752075761 2.48802576326527e-15 -38.7649922453906 339.14524457331 -0.114302036857872 0.90915122118114 PTPRA other 5.44823235149083e-12 1 3.47875762219751e-11 8.83435752075761 -0.114302036857872 6.91674052966395e-05 71.9841577268772 20.0848816056 3.58399711486509 0.000452714502598384 -116.4877123804 61.3152807257838 -1.89981536415629 0.0593145289807359 IGHMBP2 other 0.517994698266533 1 1 3.58399711486509 -1.89981536415629 0.714547757235895 -17.3518413997459 32.6053289930477 -0.532178080566088 0.595379688464599 56.1689713560041 106.960286211462 0.525138566336266 0.600252015274642 ACY3 other 1 1 1 -0.532178080566088 0.525138566336266 0.89240653442109 -87.9026432680397 245.556902331455 -0.357972602005656 0.720857196610814 -294.563795237748 790.304935898492 -0.372721694952924 0.709871411291336 ALDH3B2 other 1 1 1 -0.357972602005656 -0.372721694952924 4.56449717771827e-05 125.444997802842 31.7570230525141 3.95014978562075 0.000118586365044556 -142.376768712465 96.8399192852876 -1.47022808118031 0.143540141588139 TESMIN other 0.349001454208339 1 1 3.95014978562075 -1.47022808118031 1.92115550745568e-05 244.432075964616 104.288422989064 2.34380834381059 0.0203572642601494 -1125.15462151944 335.414266252257 -3.35452225718162 0.000999592923390709 MMACHC other 0.153942190812423 1 1 2.34380834381059 -3.35452225718162 4.78556523164143e-15 273.81892472006 33.2355976200995 8.23872426937995 8.22805248657787e-14 -203.385269854405 141.221030147775 -1.44019109364647 0.151911218112144 DPH2 other 6.42174998433964e-11 1 1.13209774162825e-09 8.23872426937995 -1.44019109364647 1.29663624345459e-07 70.9743470656963 18.4028299409967 3.8567083048235 0.000168105109813803 -188.634784943505 59.1875063857447 -3.1870709962692 0.00173853793552464 TOE1 essential 0.00127809434517319 1 1 3.8567083048235 -3.1870709962692 2.84773111038142e-06 504.875993634632 124.294669687175 4.06192795640636 7.72884607552619e-05 -791.694096007145 391.427002659058 -2.02258426380647 0.0448466380525106 NASP essential 0.0248464539380779 1 0.715459281211459 4.06192795640636 -2.02258426380647 3.23433940528935e-10 116.876826002714 20.3970370972974 5.73008841652791 5.07939916568983e-08 -154.021364141044 65.6013106308792 -2.34783974069787 0.0201459611184412 MUTYH ts 3.7434244276819e-06 1 0.000599318307559743 5.73008841652791 -2.34783974069787 1.27763792856766e-12 186.760536128896 25.8063332409526 7.23700397050294 2.20830812270095e-11 -101.051812894299 118.08294633706 -0.855769745157384 0.393490076458148 CTNNBL1 essential 1.61723408998094e-08 1 2.92446244689286e-07 7.23700397050294 -0.855769745157384 0.00665377278241025 56.3155456353395 31.4464800196016 1.79083781714953 0.0753094109865183 -242.193818292868 136.486028829717 -1.77449531186107 0.0779830584450254 LPIN3 other 1 1 1 1.79083781714953 -1.77449531186107 0.0170024768406059 9.28822677526583 4.08941491136976 2.27128500691917 0.0244972773216726 -17.9678916470657 18.3782917460514 -0.977669301115875 0.329751596770648 ZSWIM3 other 1 1 1 2.27128500691917 -0.977669301115875 2.37392296019962e-05 1328.34479518299 292.366933267242 4.54341665912265 1.11624989912168e-05 -137.385375479786 1200.42284926191 -0.114447484537851 0.909033125819359 RBM38 other 0.188560700728656 1 0.112830539803219 4.54341665912265 -0.114447484537851 0.25576926734135 62.0893955461296 43.1702618012326 1.43824459142744 0.152447786008769 -49.4036938847648 197.234350441241 -0.250482199344291 0.802557226356651 VSTM2L other 1 1 1 1.43824459142744 -0.250482199344291 0.000450675481941355 131.656215097863 34.9406890325066 3.76799138034681 0.000233377198287418 -6.62313016093911 153.222625417292 -0.0432255363259927 0.965577383040572 OSER1 other 1 1 1 3.76799138034681 -0.0432255363259927 0.00139580483960816 339.045379643701 94.9287289345536 3.57157820871538 0.000473007093247061 123.322939744036 416.28340704291 0.296247550725279 0.767437591528722 SERINC3 other 1 1 1 3.57157820871538 0.296247550725279 0.0647516080994166 22.6694986098154 10.2501418686673 2.21162779015884 0.028579521846875 -4.35981535022493 39.0476378413679 -0.11165375401034 0.911254517501379 PPP1R3D other 1 1 1 2.21162779015884 -0.11165375401034 0.00610302654516203 7.62363571161282 6.00921854886265 1.26865675621928 0.206453315083226 -10.8916910939254 8.43650171795615 -1.29101983950808 0.19860667555231 DMGDH other 1 1 1 1.26865675621928 -1.29101983950808 0.177016475858878 -4.68747661219903 19.2281004783468 -0.243782614797426 0.80771948704474 -40.8279281526755 26.9948415754173 -1.51243444191409 0.132446576882445 BHMT2 other 1 1 1 -0.243782614797426 -1.51243444191409 6.25034873958611e-14 304.265842322797 63.0613033528057 4.82492156276151 3.35801982214737e-06 -149.078032550722 89.2117741638144 -1.67105781661711 0.0967544710666116 AP3B1 other 8.20170761608489e-10 1 0.0354472572425876 4.82492156276151 -1.67105781661711 3.06974486306902e-09 304.121406779981 83.3147740770824 3.65026983687923 0.000363361432941137 -174.867489056905 117.152062127462 -1.4926539565872 0.137670914988082 ZBED3 other 3.37733329834854e-05 1 1 3.65026983687923 -1.4926539565872 7.76051641174146e-11 431.022037130907 75.5105285154516 5.70810515572948 5.50215001760738e-08 -680.251164215464 238.752544881944 -2.84918916592839 0.00496729683337944 PATJ other 9.22725401356059e-07 1 0.000648043229073797 5.70810515572948 -2.84918916592839 0.000365571623815186 126.492580747505 32.8195664856638 3.85418194974511 0.000168546464613286 -20.7739543941158 103.770363874105 -0.200191592460049 0.841588181857875 KANK4 other 1 1 1 3.85418194974511 -0.200191592460049 0.548874609437264 22.4250049064503 34.9298432927846 0.642001302968418 0.52186548480326 78.5590736621745 72.0837950078158 1.08982987998421 0.277559367102837 SLC14A2 other 1 1 1 0.642001302968418 1.08982987998421 2.54721316223924e-07 91.8517946104141 32.4174049046611 2.83340985746849 0.005222626336718 -195.594487649551 74.3727484209848 -2.62992146723413 0.00940730624117044 FBXO44 other 0.00244710768496324 1 1 2.83340985746849 -2.62992146723413 4.89292199031436e-12 31.6525233460486 5.35057027707575 5.91572892363685 2.10668520521419e-08 -10.4881712863109 11.9971776331721 -0.874219887960249 0.383377679339286 RSG1 other 6.07603052757237e-08 1 0.000252907558885964 5.91572892363685 -0.874219887960249 5.28669741863913e-12 126.356669936915 22.5395281680664 5.60600332867371 9.25081376786048e-08 -64.4484004099685 52.4532667646198 -1.22868229922029 0.221053163256497 CASP9 other 6.55867681756371e-08 1 0.00107679472257896 5.60600332867371 -1.22868229922029 0.000185106617139032 207.667070039115 62.3026863512574 3.33319608192021 0.00107383880608353 -96.0669090077513 100.165163223675 -0.959085034317047 0.3390095566055 DCTN4 essential 1 1 1 3.33319608192021 -0.959085034317047 0.196690100347232 7.59300437042288 4.97775527135124 1.52538723912832 0.129213619940161 -1.63087644696432 7.96923974090544 -0.204646428014101 0.838118600792311 PDE6A other 1 1 1 1.52538723912832 -0.204646428014101 0.0541053518998767 -7.15847238617873 7.87366589186106 -0.90916638888353 0.364673820071701 -30.9488562039371 12.9109630284424 -2.39709897207186 0.0177159592009923 ATP8A2 other 1 1 1 -0.90916638888353 -2.39709897207186 0.0170009018529426 2.2428556756618 3.13566318409379 0.715273147651534 0.47550941753525 -10.5116226324663 5.28211028438656 -1.99004224950352 0.0483336616379931 MTUS2 other 1 1 1 0.715273147651534 -1.99004224950352 3.70685891254888e-14 51.9786519549053 10.7655049292973 4.82825954716254 3.41889556226463e-06 -58.5247361477573 17.7672920207932 -3.29395926398155 0.00123778310864364 ZMYM5 other 4.89008827743448e-10 1 0.0360693481818919 4.82825954716254 -3.29395926398155 2.14153029545644e-12 111.148812848074 19.2091330049437 5.78624828197445 3.82591559669925e-08 -52.4794086824183 32.0079373565091 -1.63957483726286 0.103108635995225 USPL1 essential 2.6912611223001e-08 1 0.000454059663016267 5.78624828197445 -1.63957483726286 7.50396627297485e-11 165.535358010768 31.6052613835562 5.2375886407601 5.49314836824637e-07 -70.7961359272836 52.0431246480639 -1.36033599838662 0.175791921201227 XPO4 other 8.93047026146737e-07 1 0.00610233852228489 5.2375886407601 -1.36033599838662 0.000141108478813704 109.844299770251 131.222178887398 0.83708638815172 0.403832790336251 -679.700381688176 216.327311337235 -3.14199985885547 0.0020105754512952 POMP other 1 1 1 0.83708638815172 -3.14199985885547 6.69855164250096e-06 54.6782116989864 17.3307020633795 3.15499115379311 0.00192836963822814 -47.7915002761133 28.306503734894 -1.68835758466348 0.0933535348038432 CDK8 other 0.0562410395904381 1 1 3.15499115379311 -1.68835758466348 0.0240183620294791 -148.638518858038 67.6354098055415 -2.19764350190807 0.0294484794386529 29.2987025990294 112.700034904253 0.259970661268391 0.795229201975925 ALOX5AP other 1 1 1 -2.19764350190807 0.259970661268391 0.000454645316444527 7.10564868355592 32.6717181363897 0.217486226279654 0.828115472112983 -175.347386964717 53.3632225671518 -3.28592199888344 0.00125716230069208 WASF3 other 1 1 1 0.217486226279654 -3.28592199888344 0.00730193557137191 62.2692537640396 41.5150326891235 1.49992062466455 0.135669089374455 -107.388776567342 67.8071450060902 -1.58373835910208 0.11529149649736 GPR12 other 1 1 1 1.49992062466455 -1.58373835910208 0.0421627678943656 18.1174832810155 12.2746788212177 1.47600467147849 0.141958275489528 -46.964323734134 37.9199514582077 -1.23851223242979 0.217386624590856 CHRM3 other 1 1 1 1.47600467147849 -1.23851223242979 0.00014941835338474 1161.69949144706 274.144973407977 4.23753708487023 3.95769485334347e-05 429.991077207583 1409.38613353723 0.305091037137144 0.760725455247857 MYH10 other 1 1 0.377945935338945 4.23753708487023 0.305091037137144 1.80576875714669e-08 330.836430938884 62.7521499264425 5.27211308818403 4.52202939844302e-07 -446.471687885262 195.651876198668 -2.28196987710921 0.0238697757597932 PEMT other 0.00018969600793826 1 0.00505246344688039 5.27211308818403 -2.28196987710921 7.16990012531247e-13 223.926074968329 27.530679174099 8.13369236379026 1.41227002850958e-13 24.4008495416936 107.962826406512 0.226011585226726 0.82149804379711 SCO1 other 9.14018867974833e-09 1 1.93819938712655e-09 8.13369236379026 0.226011585226726 0.000170236112102059 563.139579610504 131.407495520934 4.28544488560619 3.19078983293636e-05 389.476103219549 411.179863502686 0.947215896959907 0.345003160565249 MPRIP other 1 1 0.308353075625627 4.28544488560619 0.947215896959907 0.325330207305896 -750.792821560863 1076.44067939419 -0.697477191203327 0.486583876504566 4215.10165823897 3751.14458194972 1.12368413590929 0.262942188631505 CHI3L1 other 1 1 1 -0.697477191203327 1.12368413590929 0.43546625816796 -7.03580704219355 5.45507248171126 -1.28977333771126 0.199114382467856 -7.64057213126663 19.0096546661822 -0.401931137910624 0.688306819333937 MYBPH other 1 1 1 -1.28977333771126 -0.401931137910624 0.111186564560925 72.0858055259871 39.5152767163059 1.8242515684128 0.0700523656972528 -96.8317674827603 147.552722798433 -0.656251986722325 0.512641354623135 PIK3C2B other 1 1 1 1.8242515684128 -0.656251986722325 7.58189179666228e-10 156.132010208879 25.4332165863107 6.13890145114072 6.67553448863983e-09 -159.255255557795 91.6301119472742 -1.73802314734084 0.0841927180649401 DSTYK other 8.61302908100835e-06 1 8.19088081756107e-05 6.13890145114072 -1.73802314734084 0.469087477686604 16.4343679482267 16.8753681401435 0.973867225398909 0.331690346347762 -29.2944682790729 58.8067201277935 -0.498148310523232 0.619109103015418 CHIT1 other 1 1 1 0.973867225398909 -0.498148310523232 0.011837996742209 126.814694509227 52.5570890847101 2.41289418264453 0.0169936626623597 -234.758008544172 192.869719776435 -1.21718437096446 0.225384021544011 SLC41A1 other 1 1 1 2.41289418264453 -1.21718437096446 0.000247195092902595 608.054284237405 156.665260666674 3.88123239095821 0.000156056369203274 -341.079623832798 585.360027444321 -0.582683490230704 0.560993096370826 LGR6 other 1 1 1 3.88123239095821 -0.582683490230704 3.86113279833638e-06 106.222155066353 22.0812717734075 4.81050893066204 3.55693916034245e-06 -68.0482733907479 81.4773442630676 -0.835180306945684 0.404910016543973 TMCC2 other 0.0332482145264746 1 0.0374865818108491 4.81050893066204 -0.835180306945684 0.573961294979482 -4.18966213681874 15.4623972457445 -0.270958123131379 0.786790848408871 18.8106840935976 26.4099068178643 0.712258631706857 0.477396491415453 DCLK1 other 1 1 1 -0.270958123131379 0.712258631706857 0.0151713314760448 353.304365388499 156.004045624993 2.26471284108735 0.0249439870330881 -92.4936091635645 266.45624495903 -0.347124944201575 0.728977598346727 CCNA1 other 1 1 1 2.26471284108735 -0.347124944201575 1.84381540338697e-11 160.657847157363 29.426274712752 5.45967332683606 1.85671147835019e-07 -71.6705807141182 51.6374330146339 -1.38795785402049 0.167141732430239 COG6 other 2.24632030594634e-07 1 0.00212497426586699 5.45967332683606 -1.38795785402049 0.383473058479495 90.0655712539133 85.2069289692045 1.05702168055446 0.292167793027849 194.133483555103 145.446345521327 1.33474294496204 0.183943315131796 EPSTI1 other 1 1 1 1.05702168055446 1.33474294496204 0.0919156878647009 -722.560640089837 416.540737102885 -1.73466980712469 0.0848398639354907 164.000643152468 700.153355927237 0.234235316826092 0.815119592417088 POSTN other 1 1 1 -1.73466980712469 0.234235316826092 2.97965782962033e-10 58.1403084410825 11.762108623208 4.94301747276548 2.02306107624901e-06 -34.1818834843287 19.974418855657 -1.71128300309213 0.0890821963787619 RFXAP other 3.45431732187885e-06 1 0.0217033992259993 4.94301747276548 -1.71128300309213 2.46232137315521e-06 8179.54284762976 5194.87583782561 1.57454058633544 0.117441648618233 -29737.8837640987 8878.74473653018 -3.34933424110583 0.00102157564438643 TPT1 essential 0.0216290309417954 1 1 1.57454058633544 -3.34933424110583 4.34160524729189e-14 134.555409757843 22.4694746216554 5.98836474922127 1.48639939575152e-08 -75.141635850332 38.6614994649667 -1.94357789765557 0.0538059169961521 GPALPP1 other 5.72049907383179e-10 1 0.000179542183012826 5.98836474922127 -1.94357789765557 5.2720093679888e-12 233.366435676763 43.8951605174252 5.31645021742484 3.68401095344763e-07 -150.433264408926 73.9318248377742 -2.03475654414072 0.0436020015780028 RFC3 essential 6.54098202286371e-08 1 0.00413714430072169 5.31645021742484 -2.03475654414072 0.00328298702368767 42.9334281856327 20.1840264367051 2.12709928419224 0.0349945080244491 -38.8218415543692 33.9961850447242 -1.14194700091485 0.255237077172619 STARD13 other 1 1 1 2.12709928419224 -1.14194700091485 4.92578605659511e-12 243.403783074569 30.9762724150966 7.8577493060767 5.81270311678393e-13 8.21077520227431 123.279399116124 0.0666029787713363 0.946982513305454 FAM104A other 6.11536338926283e-08 1 7.92329561848817e-09 7.8577493060767 0.0666029787713363 0.00209451793606987 106.839450781123 36.4926981838915 2.92769392503522 0.00392286581016474 -293.787934482946 146.057047273979 -2.01146017919867 0.0459877634399454 SLC39A11 other 1 1 1 2.92769392503522 -2.01146017919867 1.18048383030618e-05 537.994134500013 133.765796531838 4.02191104489079 9.0674934653919e-05 63.9875817260221 294.534082371059 0.217250177673528 0.828304724718396 EPHB2 other 0.096835088600016 1 0.833574674273477 4.02191104489079 0.217250177673528 8.15643010811749e-15 880.647727272727 125.738354536915 7.00381145050044 7.12574436739463e-11 -54.8655303030298 278.84637509327 -0.196758987039649 0.84427390357896 SRRM1 essential 1.0901068839499e-10 1 9.3226113558624e-07 7.00381145050044 -0.196758987039649 0.00588214819516719 666.551903275839 247.02196021015 2.69835079726831 0.00782593158051864 -159.475875021024 371.291616239265 -0.429516498746514 0.668207696519135 BTBD2 other 1 1 1 2.69835079726831 -0.429516498746514 0.000446938146429492 10.6041703512433 2.86934927445997 3.69567080788347 0.000305532908799047 4.80932640043391 9.49345646749093 0.506593822482128 0.613173902758287 PRAM1 other 1 1 1 3.69567080788347 0.506593822482128 1.17597513549403e-07 118.791212038703 27.2491261723963 4.35945032832063 2.39136837209806e-05 -48.3199208399465 54.0946762969839 -0.893247249963497 0.373136839470136 KMT5C other 0.00116268661646294 1 0.233756258372585 4.35945032832063 -0.893247249963497 2.05081953137119e-22 227.154646103781 23.2826229093326 9.75640274673384 9.188531640446e-18 -65.6597821088747 77.0322975338567 -0.852366918953915 0.395351505382362 ZNF414 other 2.92980078251688e-18 1 1.30376075446288e-13 9.75640274673384 -0.852366918953915 0.0633086770958448 22.5000703482235 41.7412515849333 0.539036791995596 0.590783401477785 -119.496552937038 75.7020681306466 -1.57851107489971 0.116878487621956 PDE6B other 1 1 1 0.539036791995596 -1.57851107489971 6.8659414317167e-12 389.942693974005 74.597786865301 5.22726893598215 5.5575599898192e-07 -282.278246028619 147.439601741175 -1.9145347837018 0.0574182384408654 HSPBP1 other 8.48699020374501e-08 1 0.00617167036869422 5.22726893598215 -1.9145347837018 0.000672352416277737 269.949442191617 86.3360675770096 3.12672848981486 0.00215020276782153 -92.6270999570201 129.769264413331 -0.713783039271851 0.476549617928336 CSNK1G2 other 1 1 1 3.12672848981486 -0.713783039271851 5.28871885834856e-07 38.4655750182353 10.7566389328898 3.57598458572611 0.000466541009157968 -13.6650915638621 15.6081953055703 -0.875507468758112 0.382661332120658 SLF1 other 0.00493966341369755 1 1 3.57598458572611 -0.875507468758112 3.27582136075402e-05 341.352941742992 311.067820431739 1.09735858009748 0.274208725993277 -1493.40796760182 591.422456338619 -2.5251120440154 0.0125845386674809 CNDP2 other 0.255514066138814 1 1 1.09735858009748 -2.5251120440154 0.155098741066873 2.64591611479026 45.1418144545285 0.0586134196589616 0.953339624788658 -280.574039735099 150.150465658131 -1.86861917813777 0.0636658249664813 MACROD1 other 1 1 1 0.0586134196589616 -1.86861917813777 3.14577452770388e-06 575.52725579702 204.810599099421 2.81004624920629 0.00563802830363447 -2276.49640136664 650.027436112602 -3.5021543321016 0.000613813539131077 RTN3 other 0.0273053229004696 1 1 2.81004624920629 -3.5021543321016 0.0241004849787993 -592.675240062829 244.109904856395 -2.42790328565933 0.0164202894025255 -1508.74612533562 801.467580405578 -1.88247929451136 0.0617884665761228 RARRES3 other 1 1 1 -2.42790328565933 -1.88247929451136 0.0586351022577217 -15.0102679573187 7.26349314265625 -2.06653570981819 0.040569249203396 -40.6207355478693 23.8476774539807 -1.70334136841023 0.0906614435218358 HRASLS2 other 1 1 1 -2.06653570981819 -1.70334136841023 0.732118474871095 18.814790205455 56.6439657570528 0.332158773736854 0.740218120916289 115.839814330615 147.047691547759 0.787770369676235 0.432034067965893 MYH11 other 1 1 1 0.332158773736854 0.787770369676235 7.98961243684622e-12 178.718689855572 36.4998879676104 4.89641749076505 2.42970751221451e-06 -268.956143424749 94.753681096572 -2.83847698909588 0.0051404702537388 FOPNL other 9.85279005711876e-08 1 0.0259055414952311 4.89641749076505 -2.83847698909588 1.84445024105661e-06 117.887747125134 24.8433492256626 4.74524372918925 4.76459828191037e-06 -128.407223701354 100.934546245001 -1.27218309764496 0.205250868385006 MED10 other 0.0164303627473322 1 0.0497662290545538 4.74524372918925 -1.27218309764496 0.661663478872078 43.2579494064444 50.5571870311127 0.855624134701633 0.393561356694944 -30.9451640431358 211.269946744412 -0.146472153375285 0.883744037813611 PDZD2 other 1 1 1 0.855624134701633 -0.146472153375285 3.49986684164053e-13 373.752479371628 45.2827935577229 8.25374165344278 6.64785052068635e-14 342.322227952326 82.0591676345303 4.17165123435005 5.05107076792939e-05 MORC2 other 4.50362865182303e-09 0.726849083505039 9.15674930719338e-10 8.25374165344278 4.17165123435005 0.256256045798419 38.7276618096224 47.3135493329982 0.818532161623569 0.414326424526803 -69.3374803027055 77.4168562999378 -0.895638025316732 0.371853048898931 LARGE1 other 1 1 1 0.818532161623569 -0.895638025316732 2.7762853550483e-39 70.8075237992213 3.85414688759008 18.3717761321484 2.47035873835078e-40 21.6642656240342 21.2706693550288 1.01850417880302 0.310067505264265 GSTT2B other 4.04227147695032e-35 1 3.59857157415558e-36 18.3717761321484 1.01850417880302 5.77286198783786e-25 72.7222359917744 6.04239454259874 12.0353339192078 7.42303009967304e-24 -104.829303444224 33.3119194920903 -3.14690072029969 0.00198602316281454 SLC2A11 other 8.31465312108287e-21 1 1.07099478278083e-19 12.0353339192078 -3.14690072029969 0.00188251771949937 139.752038187961 63.1307026646503 2.21369369085472 0.0283102924655104 -176.146844057944 125.550521209179 -1.40299572125604 0.162618071752021 C1QTNF6 other 1 1 1 2.21369369085472 -1.40299572125604 0.00534531911801962 47.4924187538814 35.1506714461338 1.35110985935675 0.178681193016132 -125.826182097761 61.1962225531014 -2.05611027688153 0.0414936560087347 FAM83F other 1 1 1 1.35110985935675 -2.05611027688153 0.0663043656181378 17.6094596932883 7.5948506726381 2.31860512501315 0.0217403033538593 17.8506480702757 14.3161667122355 1.24688741260741 0.214344218199079 SEC14L4 other 1 1 1 2.31860512501315 1.24688741260741 0.613569291131631 -9.80278962074073 13.9755545488425 -0.701424017664658 0.484103954582238 21.3044760833991 45.3510297326564 0.469768298735192 0.639189408912929 GIMAP6 other 1 1 1 -0.701424017664658 0.469768298735192 0.672417163752822 -16.1219002667914 21.5989202722647 -0.746421583281347 0.456558172332133 17.9137380843713 70.089045270971 0.255585420162524 0.798614255634486 GIMAP4 other 1 1 1 -0.746421583281347 0.255585420162524 3.56787313999057e-05 173.920881510571 41.0551198894508 4.23627752102267 3.884984779753e-05 -129.504807852928 144.297360326696 -0.897485633553676 0.370851750482527 ADCK2 other 0.276831276931868 1 0.371326845248791 4.23627752102267 -0.897485633553676 1.03907760515959e-09 466.637724149938 69.1045507546988 6.75263378538365 2.79377660577214e-10 57.1104612232326 250.992930182827 0.227538126996775 0.820307129059923 MKRN1 other 1.17239126190157e-05 1 3.58776791713258e-06 6.75263378538365 0.227538126996775 0.000323505745202873 317.39577860584 94.3093115534066 3.36547657254503 0.000973468678291327 -389.821441161183 302.603273192003 -1.28822612210754 0.199677633047285 AGAP3 other 1 1 1 3.36547657254503 -1.28822612210754 3.92808453391791e-09 111.603542948594 16.5470114846387 6.74463440435759 5.32516815698876e-10 96.2978946497061 51.3572285367063 1.8750601890614 0.0631558081577934 KRBA1 other 4.29064673639854e-05 1 6.78000409747809e-06 6.74463440435759 1.8750601890614 0.000299804430789855 79.35154256553 19.3915237299838 4.0920736127009 7.37067542134582e-05 31.4868608542929 59.0156161227064 0.533534391792587 0.594554225585158 ZNF767P other 1 1 0.683851265592465 4.0920736127009 0.533534391792587 2.08272951401308e-12 122.910773034235 15.7783721988744 7.78982593926914 9.24632352390296e-13 36.0785097848335 49.5316166717337 0.728393543540897 0.467478861992989 ACTR3B other 2.61819927206584e-08 1 1.25657536689841e-08 7.78982593926914 0.728393543540897 0.1160571493544 438.088593360386 210.402011434394 2.08215021507524 0.0390500563181603 426.837818645769 440.254891765773 0.96952430655298 0.333865418947951 NTS other 1 1 1 2.08215021507524 0.96952430655298 0.000224778490921076 246.714900153609 105.20124062499 2.34517101402892 0.0203283098233644 -335.562320412037 213.832692001034 -1.56927510602735 0.118690945542307 BTG1 other 1 1 1 2.34517101402892 -1.56927510602735 0.00219223341052861 14.5318982003628 21.338138656593 0.681029326607775 0.496917091035136 -114.869747555767 44.7090106527217 -2.56927509418674 0.0111799081317535 LRRIQ1 other 1 1 1 0.681029326607775 -2.56927509418674 4.63270635057257e-08 23.508501896485 19.9757925755768 1.17684951961442 0.241157653749777 -187.769504139742 41.8860173938997 -4.48286840866109 1.47252320408542e-05 C12orf29 other 0.000472304412440874 0.213471688896263 1 1.17684951961442 -4.48286840866109 1.60395206256984e-09 598.352290580086 87.9629798778566 6.80231946906466 2.10890067742061e-10 463.133799648295 328.854709088351 1.4083234536376 0.161037963138837 ATP13A3 other 1.79113326827174e-05 1 2.72048187387258e-06 6.80231946906466 1.4083234536376 0.393500602461518 21.4554751473585 15.8332787377389 1.35508731342037 0.177361312322551 16.578886136298 37.9742712115415 0.436582075372631 0.66302201057533 SFTPD other 1 1 1 1.35508731342037 0.436582075372631 0.237393211978057 1.99437413812038 17.3800207463889 0.114750964180222 0.908791032148057 -60.9544927571605 41.6839514049913 -1.46230121431966 0.145683289409449 DYDC2 other 1 1 1 0.114750964180222 -1.46230121431966 2.09652977533244e-06 172.253847186459 44.9703959895918 3.83038315309313 0.000185399625275788 -169.464778362195 107.856246459478 -1.57120967885587 0.118173057635364 TMEM254 other 0.018560578101018 1 1 3.83038315309313 -1.57120967885587 0.225388273529874 149.610217927125 88.8720605205013 1.68343365789986 0.0944136684559399 -72.6944124089777 662.69620955394 -0.10969492711888 0.912800931911611 TMTC1 other 1 1 1 1.68343365789986 -0.10969492711888 2.39979909640643e-54 324.770160507165 12.7743050634565 25.4237047646714 6.56781927942232e-55 -309.611403428839 232.605029029905 -1.33106065986661 0.18528732672419 KRAS essential 3.50226680129555e-50 1 9.58704580217276e-51 25.4237047646714 -1.33106065986661 3.73118145463327e-35 287.214015058314 17.2945242882307 16.6072226255896 1.53351530432602e-35 -137.591944741445 161.853133654115 -0.850103681251447 0.396649917139184 IPO8 other 5.42625718947316e-31 1 2.23157147085522e-31 16.6072226255896 -0.850103681251447 6.27264242893211e-14 797.155483870968 126.934539936909 6.28005178312527 3.21208373199017e-09 -440.535760368663 190.328440163551 -2.3146081583504 0.021938411544737 LARS essential 8.23033413100182e-10 1 3.98298382766781e-05 6.28005178312527 -2.3146081583504 0.0110500767773656 33.59706955775 11.9367832849168 2.81458318843763 0.00551809491151662 3.44091884929155 17.7209001894207 0.194172915174239 0.846294739419057 SPINK5 other 1 1 1 2.81458318843763 0.194172915174239 3.72660714316783e-06 65.794713986121 14.4753575154608 4.54529112084775 1.11225757301873e-05 -16.8350322788232 45.0624314883409 -0.373593517322274 0.709227313658325 IMPA1 other 0.0321159003598204 1 0.112460363207924 4.54529112084775 -0.373593517322274 0.000258838939322306 56.7635151002769 19.0466777055294 2.98023182719147 0.0033612765931888 -87.7769882646594 62.6652349822038 -1.40072862233082 0.163360541545019 LRRCC1 other 1 1 1 2.98023182719147 -1.40072862233082 1.44472757867382e-07 252.472480142254 63.7471452722135 3.96052998238815 0.000115213641405177 -469.843373342391 209.845540749862 -2.2389962239057 0.0266277061787512 E2F5 other 0.00141901142777342 1 1 3.96052998238815 -2.2389962239057 3.95918277349915e-08 9.92728198895428 33.8344487753712 0.293407528370333 0.769618938565669 -356.781408068062 70.9393817631738 -5.02938423200743 1.39602028699848e-06 CCDC59 essential 0.000405697458800458 0.0203609558858728 1 0.293407528370333 -5.02938423200743 6.97347568043025e-07 61.6460867105736 52.5168677033459 1.17383403478662 0.24228548208115 -287.872661521678 83.1274455601197 -3.46302787944424 0.000692851353524294 SWAP70 other 0.00644349152871755 1 1 1.17383403478662 -3.46302787944424 1.9154310834915e-05 -31.7537807052134 16.265861032437 -1.95217336739141 0.0527432393777385 -122.366893629311 25.9304155711344 -4.71904868989176 5.30591737052759e-06 ARNTL other 0.153521801341844 0.0771692622369533 1 -1.95217336739141 -4.71904868989176 0.367448214471365 19.150887321109 41.4408478023144 0.462125857377837 0.644634917302914 86.5538140885142 64.7897109524081 1.33591912691342 0.18352131920842 LYVE1 other 1 1 1 0.462125857377837 1.33591912691342 0.000922016481761895 -27.6016552667201 24.1744753379579 -1.14176853399507 0.255299776286261 -134.568618855815 37.7950103010426 -3.56048636536825 0.000491001364406312 AMPD3 other 1 1 1 -1.14176853399507 -3.56048636536825 0.0032543338261501 5.37152734201188 3.63006473981769 1.47973320781095 0.141000561838586 -9.22341384385449 5.66743675855453 -1.62744009978276 0.105701299010045 MICALCL other 1 1 1 1.47973320781095 -1.62744009978276 4.98246235941668e-11 99.8106944794021 45.2619656733021 2.20517807820873 0.0289239372597462 -293.61532848986 71.3659245898053 -4.1142230017686 6.30762459434607e-05 SBF2 other 5.96898990658119e-07 0.906657959191304 1 2.20517807820873 -4.1142230017686 0.17394070527923 21.8373773877114 199.641896529939 0.109382738629898 0.913042256423324 -449.537230451533 312.653372684867 -1.43781346924613 0.15252914747712 MICAL2 other 1 1 1 0.109382738629898 -1.43781346924613 3.7837739377948e-12 141.634715025906 31.7351986392732 4.46301649584223 1.55893061767654e-05 -137.470957185711 50.4204801034921 -2.72649044403267 0.00714872403051004 RRAS2 other 4.71723096824878e-08 1 0.155253900214407 4.46301649584223 -2.72649044403267 1.64719532554527e-11 390.340511619725 90.3429389830645 4.32065323547751 2.7685596871082e-05 -348.005568732598 131.783060732671 -2.6407458348425 0.00911920313183295 HSD17B4 other 2.0100724557629e-07 1 0.26918705837753 4.32065323547751 -2.6407458348425 1.36943702986268e-09 144.862151100015 24.0823275835347 6.0152886218132 1.27121980222434e-08 -105.345295746658 84.1032686794361 -1.25257076687693 0.212273104722815 ZFC3H1 essential 1.53554974158503e-05 1 0.000153957430247389 6.0152886218132 -1.25257076687693 6.1359152494904e-07 29.779847319412 6.08380604326018 4.89493700286566 2.48588541870619e-06 17.8739047325197 11.5607431733033 1.54608613517123 0.124163264793628 TEX15 other 0.00569719730915184 1 0.0264846232508958 4.89493700286566 1.54608613517123 3.52192211209151e-12 346.013507299829 232.89224342394 1.48572362141736 0.139423363794333 -1953.8744589903 444.874726363017 -4.39196552018993 2.09494652652977e-05 SARAF other 4.39606318031263e-08 0.303222560249919 1 1.48572362141736 -4.39196552018993 1.24759954282116e-16 200.746494811609 24.249286175289 8.27844965664092 6.99693480494495e-14 85.6518772626554 46.8926792360884 1.82655115165051 0.0697959948116244 RNF122 other 1.71382749197343e-12 1 9.63547891988969e-10 8.27844965664092 1.82655115165051 0.000119905830953326 302.055671501616 78.741294102696 3.83605165426503 0.000187952535797536 -235.777522696442 246.72779827768 -0.955617990118348 0.340900801956265 DPF2 other 0.871235767706866 1 1 3.83605165426503 -0.955617990118348 3.77644049083463e-07 340.257656766697 69.7875620163286 4.87562033886618 2.83284910378638e-06 -323.745171060358 211.928235811737 -1.52761697760723 0.128801236599661 MEN1 ts 0.00357326799242773 1 0.0300536961420697 4.87562033886618 -1.52761697760723 0.185121697882791 13.9835896151076 7.59346308915929 1.84152993843759 0.0674430174987768 8.24956938398423 12.5834704904768 0.655587772087796 0.513055058849915 GSC other 1 1 1 1.84152993843759 0.655587772087796 0.0197836178496083 20.278835178449 8.44258985413108 2.40196853439781 0.0174827610776087 -6.25078623432814 14.8568968523187 -0.420732963044876 0.674529117209584 UNC79 other 1 1 1 2.40196853439781 -0.420732963044876 0.000820698233611938 31.0287985456762 8.05839425830024 3.85049397573421 0.00017165111635909 24.0359516053453 14.1628173633848 1.69711654034921 0.0916688381272291 CATSPERB other 1 1 1 3.85049397573421 1.69711654034921 4.3055951111047e-06 67.62916487376 81.2314748287185 0.832548775168249 0.406380193206371 -470.061959947434 118.347848435284 -3.9718673905971 0.000108913457553092 COX16 other 0.0368903389119451 1 1 0.832548775168249 -3.9718673905971 0.106235746750626 -138.867114484297 155.2609839347 -0.894410887816492 0.372488822392668 -481.072389825919 226.890523975716 -2.12028418550176 0.035574090886124 TTC9 other 1 1 1 -0.894410887816492 -2.12028418550176 4.36790023965234e-13 132.893257974052 28.2097338332523 4.71090081032257 5.44270258202853e-06 -140.875962385622 41.2242736612699 -3.41730611297525 0.000807924582848247 MED6 other 5.60663674761775e-09 1 0.0565496798272765 4.71090081032257 -3.41730611297525 9.49113888251062e-06 86.8404771454079 81.8454580064646 1.06102988804276 0.2903593054046 -429.71735474105 118.834629413825 -3.61609538280815 0.000406279097662781 EIF2S1 essential 0.0785771388083054 1 1 1.06102988804276 -3.61609538280815 0.0099348749543745 468.026051135093 155.84078370357 3.00323214509329 0.0031183694336461 496.789408797151 285.369202294411 1.74086553420233 0.083704369816413 LOXL2 other 1 1 1 3.00323214509329 1.74086553420233 9.12749673271866e-12 136.97127163973 46.7790532896307 2.92804710671843 0.00393595300843408 -234.51635704837 87.0033210610621 -2.69548741574793 0.00782048932164052 ELP3 essential 1.12405332580301e-07 1 1 2.92804710671843 -2.69548741574793 0.000698125858776692 4.98101464200956 3.47661103794004 1.43272128738362 0.153964337212852 -8.91768533858719 6.3662264460376 -1.40078041743828 0.163291514953546 PEBP4 other 1 1 1 1.43272128738362 -1.40078041743828 0.146683058627247 -60.7176140912734 35.0047011977135 -1.73455598858931 0.0848334296939419 -40.2393826172051 63.648862474897 -0.632208983044677 0.528193924956349 ADAMDEC1 other 1 1 1 -1.73455598858931 -0.632208983044677 0.00172097157911722 3.55186308923527 39.8244966903538 0.0891878965063127 0.929052353073675 -206.537259620587 80.3985380176288 -2.56891810116373 0.0111841675512064 CTIF other 1 1 1 0.0891878965063127 -2.56891810116373 0.878993496865116 -1.08444344700074 2.43658800576838 -0.44506639794394 0.656900793238715 -2.40120777621756 4.92249536554007 -0.487802953158111 0.62638769900398 MRO other 1 1 1 -0.44506639794394 -0.487802953158111 1.06424096026733e-06 207.874937502605 85.90180967819 2.41991336714974 0.0167042678399964 -266.309643348193 159.65079052266 -1.66807594548299 0.0973594259721765 MBD2 other 0.00969097818419429 1 1 2.41991336714974 -1.66807594548299 1.22441757550884e-11 124.636366489065 37.7547110884985 3.30121362065021 0.00120486849967045 -210.469969615782 76.2200109745133 -2.76134793113793 0.00648068292299714 IER3IP1 other 1.50052373878608e-07 1 1 3.30121362065021 -2.76134793113793 3.51445369998497e-09 34.2043516549604 37.0260617945765 0.923791243171603 0.35714038808706 -204.735313701484 53.2492529595922 -3.84484856260512 0.000180499645010091 MRPS36 other 3.85254414592352e-05 1 1 0.923791243171603 -3.84484856260512 0.000195331306794365 172.800373735421 191.870094865973 0.900611290446938 0.369298758044009 -602.346961788775 275.939128324896 -2.18289796537866 0.0306636188027607 CCNB1 other 1 1 1 0.900611290446938 -2.18289796537866 9.36163354480995e-17 71.6915823614063 37.4238384431945 1.91566619950614 0.0573895916936616 -278.46411925167 53.8213178338204 -5.1738628940945 7.5563372329556e-07 CDK7 essential 1.28844162477219e-12 0.0110284741914987 1 1.91566619950614 -5.1738628940945 0.0556683880362913 -14.1060623727476 18.7843506713744 -0.750947563720896 0.453868561612382 29.1604299898647 27.4202382546491 1.06346377150536 0.289292165746425 CD180 other 1 1 1 -0.750947563720896 1.06346377150536 0.633184212928563 -6.98359936178804 24.991668058602 -0.279437104614724 0.78027485681618 -47.9723313319791 51.339263595539 -0.934417986785217 0.351514188215502 IRAK2 other 1 1 1 -0.279437104614724 -0.934417986785217 0.00262489912890348 62.7702952029521 19.882783019362 3.15701756347821 0.00191803109463892 -4.04797047970471 41.1576414548182 -0.0983528291860083 0.921780029325468 CAMK1 other 1 1 1 3.15701756347821 -0.0983528291860083 6.45472865780645e-11 186.034864690616 37.5365874359788 4.95609423759979 1.93225883789954e-06 -196.926121241176 73.139105982172 -2.69248739913745 0.00790430423496225 THUMPD3 other 7.70307318022622e-07 1 0.0207505276602031 4.95609423759979 -2.69248739913745 2.94148008562175e-09 246.332465023476 47.6337934146701 5.17138038700927 6.9473903823938e-07 -106.802991314262 97.6866363452933 -1.09332243702962 0.275916372881048 VHL ts 3.2388637222781e-05 1 0.00766505580889508 5.17138038700927 -1.09332243702962 0.917465669083558 -34.2078371880009 276.51816285348 -0.123709187255547 0.901710054450962 154.100162746573 528.593049159991 0.291528923793947 0.771046925916657 BHLHE40 other 1 1 1 -0.123709187255547 0.291528923793947 2.50287162338265e-07 278.854877490268 72.4463621313465 3.84912187840018 0.000174560753517436 -279.967246229841 138.488709256501 -2.02158896369885 0.0449852004922215 ARL8B other 0.00240651106588242 1 1 3.84912187840018 -2.02158896369885 0.000243879720738987 112.85926910869 38.9475144303062 2.89772712737918 0.00431854193699931 -98.8653578270974 74.3075183990128 -1.33048929579663 0.185362913165325 EDEM1 other 1 1 1 2.89772712737918 -1.33048929579663 0.0219506489660453 555.079250315878 232.693864408354 2.38544858811478 0.0183593739467936 -69.8901446019936 441.051107718379 -0.158462689196147 0.874314230393282 CHL1 other 1 1 1 2.38544858811478 -0.158462689196147 0.000703127710619128 248.989847991314 88.7826822471901 2.80448665988794 0.00569381028523313 -96.4351248642781 126.542086816287 -0.762079457439973 0.447185772425249 MEIS2 other 1 1 1 2.80448665988794 -0.762079457439973 7.52389084173602e-09 48.7394735016647 15.6294817237405 3.11843184330493 0.00217530041649548 -71.3999549112099 22.9674704253324 -3.10874265162688 0.00224343850855593 DPH6 other 8.07614442951944e-05 1 1 3.11843184330493 -3.10874265162688 7.0660811387464e-07 55.6496225829802 28.4278421068077 1.95757463313241 0.0520876290262376 -140.142746355082 41.2046749261405 -3.40113704588832 0.000854966622751358 KATNBL1 other 0.00652411271540455 1 1 1.95757463313241 -3.40113704588832 2.4555724654853e-06 3.80183093958939 58.9153662479918 0.0645303794528983 0.948631067566706 -424.774083616564 93.6430132896008 -4.53610011782625 1.14138801088583e-05 EMC7 essential 0.0215746596817538 0.165649642019861 1 0.0645303794528983 -4.53610011782625 0.060118118167659 186.573475942443 120.60735834981 1.54694936109375 0.12395498414044 -522.083564167474 404.982010462333 -1.28915248252992 0.19930346874479 GSTM1 other 1 1 1 1.54694936109375 -1.28915248252992 6.23886959826774e-06 153.32056477971 57.1558862060798 2.68249825095706 0.00811075683040959 -593.64169273007 179.914464677571 -3.2995773507925 0.0012046596413367 PRPF38B essential 0.0525188042782179 1 1 2.68249825095706 -3.2995773507925 0.569495545520699 16.4858180452069 19.3516614873963 0.851907111745632 0.395614736460216 -22.5202502452361 64.7430220862669 -0.347840578328719 0.728444324618621 TSPAN2 other 1 1 1 0.851907111745632 -0.347840578328719 0.390652811684806 -4.38347718865598 3.66315388353376 -1.19664019804359 0.233297789667416 -12.418442223621 12.406224096719 -1.00098483848161 0.318414611950349 GSTM5 other 1 1 1 -1.19664019804359 -1.00098483848161 0.947348796318462 4.32078655904698 59.4605065175633 0.0726664943187243 0.942167043897701 -56.9354945593831 199.659753783418 -0.285162600276189 0.775907759427553 GSTM3 other 1 1 1 0.0726664943187243 -0.285162600276189 0.442750767697041 -5.34834865063551 245.65012881092 -0.0217722200127654 0.98265839806964 -953.988987648853 779.901472843428 -1.22321731765773 0.22315314632714 VAV3 other 1 1 1 -0.0217722200127654 -1.22321731765773 0.00169209663251982 79.538294324969 38.2568748619201 2.07905885182847 0.0393612541607448 -267.621552033429 120.903567640629 -2.21351244844074 0.0284137315307034 PSRC1 other 1 1 1 2.07905885182847 -2.21351244844074 0.845545895998871 -2.19076882845189 7.75707286158062 -0.282422102711239 0.778001563091758 -14.0602470228516 24.6235264522677 -0.571008667264098 0.56883152446789 PTPN22 other 1 1 1 -0.282422102711239 -0.571008667264098 0.00388789232820636 460.71560908057 333.036112486784 1.38338033566511 0.168617486868156 -2712.74602601513 1073.27170267784 -2.52754826130864 0.0125288160082458 SORT1 other 1 1 1 1.38338033566511 -2.52754826130864 0.0236821679797855 118.774821544452 45.0100790689838 2.63884943108884 0.00918523333848588 -0.753652685190496 154.519986812137 -0.00487737994766189 0.996114824676142 WNT2B other 1 1 1 2.63884943108884 -0.00487737994766189 7.37313275790262e-07 481.292944794259 97.0272202678922 4.96039094457626 1.87352433865387e-06 -549.71400205008 424.971310180555 -1.29353203117765 0.197802354088439 PTGFRN other 0.0067962070192509 1 0.0201347660675131 4.96039094457626 -1.29353203117765 0.00809352581879567 -18.8486092111257 121.03161002932 -0.155732946182899 0.87644880638668 -1242.04335473008 407.020974361589 -3.05154631571069 0.00268475266814688 LAMTOR5 other 1 1 1 -0.155732946182899 -3.05154631571069 3.15278392821303e-09 69.9970038018984 11.219311774966 6.23897483249237 4.38950756570686e-09 -65.761518996903 51.274848428717 -1.28252975897775 0.201661953047069 TRIM45 other 3.4661706506774e-05 1 5.41796918835198e-05 6.23897483249237 -1.28252975897775 3.1002148876292e-08 40.4202954826155 24.234912423224 1.66785399413621 0.0973637419523285 -408.188377184775 78.4417613164207 -5.2037125420758 6.10820305579773e-07 CEPT1 other 0.000320097187147715 0.00891553318024236 1 1.66785399413621 -5.2037125420758 0.0139928573917439 6.23905098239523 2.62950411180522 2.37271010696841 0.0189259748753451 -14.4789855774453 11.452469150286 -1.26426759045963 0.208094981060543 CD101 other 1 1 1 2.37271010696841 -1.26426759045963 6.46076677974075e-12 3757.86505579918 483.364846827579 7.77438632631812 1.15060147926373e-12 723.323223564779 2210.1881495247 0.327267714162855 0.743924743714452 VTCN1 other 7.99261458321729e-08 1 1.56063126795057e-08 7.77438632631812 0.327267714162855 0.0297193924540876 11.3795003443742 4.26902905787542 2.66559449235453 0.00852169133327762 7.39306138208833 14.2824864294447 0.517631255496722 0.605473074920457 NGF other 1 1 1 2.66559449235453 0.517631255496722 6.59264283517966e-07 31.6697829497908 19.5608416353888 1.61903989307366 0.107498193647344 -280.53519271001 62.0926101936177 -4.51801255955004 1.24105132185096e-05 AP4B1 other 0.00611006137964451 0.180064136287356 1 1.61903989307366 -4.51801255955004 5.99875272723023e-14 141.704618998628 23.098327745633 6.13484320419768 7.32400268869579e-09 -134.207575934972 61.4334231445056 -2.18460194899582 0.0304810948042656 NAPG other 7.87816195667145e-10 1 8.96824129230799e-05 6.13484320419768 -2.18460194899582 0.00413264795773318 73.3903416800295 38.7651226232966 1.89320545669896 0.0603368668705203 -141.841324663577 103.735625550168 -1.36733474070564 0.173650895703751 SPIRE1 other 1 1 1 1.89320545669896 -1.36733474070564 4.1466818810453e-11 166.224946094936 32.4552799557773 5.12166113869393 9.48920472747894e-07 -353.343765600604 100.206498096938 -3.52615621053621 0.000564804700884165 PPHLN1 other 4.98514095739266e-07 1 0.0103830878128075 5.12166113869393 -3.52615621053621 0.336125929114182 54.680571238791 36.8977230738793 1.48194974332984 0.140569423974341 58.6416520377662 100.456794597411 0.583749981997507 0.560314637059105 FKBP11 other 1 1 1 1.48194974332984 0.583749981997507 3.95534293072062e-06 567.834706077716 252.547099362161 2.24843091649776 0.0260888357072021 -2427.05926365232 687.578256143308 -3.52986622536018 0.000560849872993118 ARF3 other 0.0340357259188509 1 1 2.24843091649776 -3.52986622536018 0.095839304675477 88.3636550193092 155.185543818864 0.569406484939403 0.569973660666431 -788.668323134898 451.575390828262 -1.74648206955732 0.0828744724679466 TMEM106C other 1 1 1 0.569406484939403 -1.74648206955732 2.41354182319101e-06 1067.75637068823 228.035283987505 4.68241735233719 6.45556052267096e-06 -584.825901964019 746.891442670583 -0.783013258088641 0.434896319531348 SLC38A2 other 0.021227100334965 1 0.0666342957150096 4.68241735233719 -0.783013258088641 7.16007659925955e-07 14.7184183428297 3.06441027521096 4.8030182061103 3.85600668232961e-06 -10.8901558316743 10.1577537941822 -1.07210275542528 0.285455008700831 PLEKHA8P1 other 0.00660803469345663 1 0.0405459102646958 4.8030182061103 -1.07210275542528 2.30387765505548e-07 1975.21584771094 411.363468286963 4.80163164691391 3.71570013385927e-06 -2016.53605328019 1295.44277518315 -1.55663846517272 0.121622448420404 YWHAQ other 0.00222255077383202 1 0.0391374695099397 4.80163164691391 -1.55663846517272 4.06565862793896e-12 633.363930871423 85.8202180461191 7.38012493199515 9.02375213826004e-12 -85.5423170875082 268.132319351611 -0.319030235871467 0.750133113431972 KIDINS220 other 5.06540408454915e-08 1 1.20376853524389e-07 7.38012493199515 -0.319030235871467 0.359782824281681 23.2316437707246 21.4999090360338 1.08054614239476 0.281599355534828 -35.8037966910541 67.8794766981063 -0.5274612951171 0.598637328557534 GRHL1 other 1 1 1 1.08054614239476 -0.5274612951171 1.85410772133238e-11 275.52119415836 40.6243234529064 6.78217311059363 2.34852913155495e-10 -112.887890353346 126.694949659401 -0.891021233733681 0.374298790538217 ROCK2 other 2.25830320458284e-07 1 3.02490552144277e-06 6.78217311059363 -0.891021233733681 0.314857294358534 59.4506858216931 89.3570524651052 0.665316101881373 0.506843533980849 411.538965712409 271.635097960465 1.51504341229242 0.131811226996526 RSAD2 other 1 1 1 0.665316101881373 1.51504341229242 0.000893517491290724 154.809935780713 49.9491050233372 3.09935354614227 0.00230628528690846 -172.673112281606 155.775479329976 -1.10847427993359 0.269385186944428 MYCN og 1 1 1 3.09935354614227 -1.10847427993359 0.0129408519273761 114.11350477059 49.6974191341323 2.29616561098676 0.0230061919299855 -163.63800297678 157.009480666499 -1.04221733797311 0.298933771497951 LPIN1 other 1 1 1 2.29616561098676 -1.04221733797311 0.480250389269251 63.1289501366103 73.5072086024585 0.858813051629046 0.391778442266779 242.589768142029 218.865412910282 1.10839700488205 0.269418438648046 CMPK2 other 1 1 1 0.858813051629046 1.10839700488205 0.000297278030612757 191.548304840316 67.4917957475816 2.8380976194011 0.00515446834724641 -411.357755606832 212.541379888285 -1.93542431983385 0.0547823686334598 IAH1 other 1 1 1 2.8380976194011 -1.93542431983385 6.110871096181e-44 9455.18816989585 485.41333723383 19.4786328364545 1.27077379256514e-43 -1631.31240145619 2814.84640382757 -0.57953869143196 0.563061737218976 LDHA other 8.90903897112228e-40 1 1.85266111218071e-39 19.4786328364545 -0.57953869143196 0.288699899516842 -3.11650924750868 10.1100037943488 -0.308259948354395 0.758295769594128 -92.6775022364617 58.5678869260523 -1.58239450150346 0.115584829540922 SAA2 other 1 1 1 -0.308259948354395 -1.58239450150346 0.607518333884827 -8.91883041343848 21.760153477119 -0.409869830321587 0.682471023301417 -36.4913391963891 36.9435786314323 -0.987758645702545 0.324820252541496 ANO3 other 1 1 1 -0.409869830321587 -0.987758645702545 9.98619201770216e-07 479.047929254693 152.045724946353 3.15068331861167 0.00195750581378901 -359.899437802796 243.20322917019 -1.47983001307497 0.140961411135601 IL6ST og 0.00911040297774968 1 1 3.15068331861167 -1.47983001307497 0.0877106919537888 371.781381938008 190.507375588413 1.95153274664406 0.052832080051288 117.315415508186 281.586887938815 0.41662243709898 0.677542333037183 FST other 1 1 1 1.95153274664406 0.41662243709898 0.000831963548287412 216.406836967213 62.1800356938076 3.48032667644102 0.000653790267572123 -192.337140859809 239.097973554063 -0.804428151359127 0.422406131988137 NAV1 other 1 1 1 3.48032667644102 -0.804428151359127 1.05677251386738e-09 215.710270993643 32.7853470694401 6.57947193716644 7.7715285448494e-10 -136.345466711275 132.912136679801 -1.02583157653801 0.306656069817003 CDC73 ts 1.19161668663686e-05 1 9.84264090205177e-06 6.57947193716644 -1.02583157653801 0.000701564766682475 140.43472798654 43.4734962365165 3.23035274693592 0.00152151171866032 -203.682271452608 151.651221524289 -1.34309680730125 0.181282860423842 TIMM17A other 1 1 1 3.23035274693592 -1.34309680730125 0.678660289127517 -8.63576090867039 17.4011363824434 -0.496275686763959 0.620398447031277 -31.2356992342087 35.4973564986242 -0.879944376574052 0.380242968840313 ERN2 other 1 1 1 -0.496275686763959 -0.879944376574052 0.000716457391764424 270.403204076584 1037.6605346819 0.260589272733088 0.794750737297254 -6612.55896289098 2105.93373446937 -3.13996535344791 0.00201927172263028 RPS15A essential 1 1 1 0.260589272733088 -3.13996535344791 2.57105492652233e-19 822.809861908134 161.268406530262 5.10211441664946 9.76091174741056e-07 -750.615950963855 301.080265099311 -2.49307589362014 0.0137217766914585 NARS essential 3.61824559809488e-15 1 0.0106725809046187 5.10211441664946 -2.49307589362014 0.861664497649281 -2.10523973690064 4.91912998314805 -0.427969934543867 0.669263253696019 -5.03115242211892 9.24274250806857 -0.544335452137384 0.586987860052837 GRP other 1 1 1 -0.427969934543867 -0.544335452137384 2.68018882980684e-39 248.938260011698 15.9896659798712 15.5686967023 1.67321155884546e-33 27.2573424542656 47.0933493969375 0.578793880735061 0.563568377034977 KIAA1468 other 3.90262295508173e-35 1 2.43268228540541e-29 15.5686967023 0.578793880735061 7.87218228239213e-23 536.054431745855 47.8479837977534 11.2032815010907 1.02716643456051e-21 72.2218870778796 182.941761562883 0.394780756787754 0.693547402050303 FBXO18 other 1.12658800643314e-18 1 1.47696261625455e-17 11.2032815010907 0.394780756787754 2.06940794286354e-14 390.941379915967 53.2984431768187 7.33494932711281 1.18417312711479e-11 -353.524000594442 206.727324601516 -1.71009807859647 0.08926165094058 RBM17 essential 2.74527657700278e-10 1 1.57708177069147e-07 7.33494932711281 -1.71009807859647 0.991448413960896 0.171982869263303 4.1477717377844 0.0414639184930582 0.966979765900038 2.10298707088722 16.0878574176232 0.130718902853001 0.896168281034616 IL2RA other 1 1 1 0.0414639184930582 0.130718902853001 2.30488726335097e-12 65.4066792115191 9.27600556437412 7.05116860459023 5.50944072893597e-11 -26.5706939332724 35.4658370849344 -0.749191225055263 0.45487743998378 ANKRD16 other 2.89447742531614e-08 1 7.228386236364e-07 7.05116860459023 -0.749191225055263 7.17339965299847e-19 237.865912695101 23.6721886651842 10.0483278525463 1.47304960965235e-18 26.2427593690008 116.81462798277 0.224653023531194 0.822548958533715 ECHDC3 other 1.00657143930874e-14 1 2.09850647391074e-14 10.0483278525463 0.224653023531194 0.0329243425902477 -37.2408796155371 19.1454643251916 -1.94515416199833 0.0535661588218793 -175.866637149367 73.2006803963669 -2.40252735626342 0.0174647183834817 IL15RA other 1 1 1 -1.94515416199833 -2.40252735626342 1.34432954746511e-14 84.87996952298 28.9275874432004 2.93422220880475 0.00385566789274787 -162.815330251941 42.2782302875975 -3.85104412233885 0.000172089425249185 CCNH essential 1.78889932881183e-10 1 1 2.93422220880475 -3.85104412233885 2.43489149059335e-18 100.045713732279 10.9643806449769 9.12461150079765 8.19418093292771e-16 -17.5282865824869 34.7840425625263 -0.503917465917849 0.615128764934769 TMEM241 other 3.40641319534009e-14 1 1.14997135212707e-11 9.12461150079765 -0.503917465917849 5.89377441374055e-08 362.943983089825 80.1295767180682 4.52946337613669 1.26757643213443e-05 -213.285435525067 190.085062846039 -1.1220525817845 0.263788601947499 KCTD1 other 0.000596685721647094 1 0.12748016177976 4.52946337613669 -1.1220525817845 1.63276576101123e-05 268.532106148836 55.681742470957 4.82262397389772 3.71863885431563e-06 260.225366520986 176.648017136538 1.47312928126359 0.143010024691508 CABLES1 other 0.131845835201657 1 0.0391647044136522 4.82262397389772 1.47312928126359 0.339301206976933 -4.66621002048543 23.5789568837499 -0.197897220114147 0.843391643376254 51.7114985770453 39.628291005853 1.3049136681016 0.19390735980161 DOCK2 other 1 1 1 -0.197897220114147 1.3049136681016 0.37367576644547 135.097973386619 136.253228406857 0.991521264972975 0.322986457161185 -304.150507143103 538.239955219249 -0.565083480320982 0.572839256969558 EMP1 other 1 1 1 0.991521264972975 -0.565083480320982 0.761412361562101 3.39428221360015 5.31372900485978 0.638775935034671 0.523969522661452 -28.1278955437231 92.9326460162572 -0.30266969412237 0.762572388474518 SOX5 other 1 1 1 0.638775935034671 -0.30266969412237 0.000112569379431987 157.510763085312 43.6969586487624 3.60461615535738 0.000425623074525414 -161.670978241342 164.62047468768 -0.982083052233124 0.327650901815648 RERG other 0.821081053576914 1 1 3.60461615535738 -0.982083052233124 0.00408291239129791 11.5485691946686 3.59546894643265 3.21197856711484 0.0016013464411512 31.2198142880368 15.7267771955307 1.98513744423803 0.0488822864669388 KLRD1 other 1 1 1 3.21197856711484 1.98513744423803 4.95298604352946e-09 91.9829760769517 14.0959642893133 6.52548305238595 9.6710046360739e-10 77.9363903976117 85.9649951752204 0.90660611611454 0.366059577795262 SPX other 5.378942843273e-05 1 1.22125446544341e-05 6.52548305238595 0.90660611611454 0.0789673799723822 323.558301158302 142.939455968897 2.26360383817822 0.025082744189847 311.603861003861 279.787583918776 1.11371582912815 0.267243875499735 LRP4 other 1 1 1 2.26360383817822 1.11371582912815 0.0125245522187357 29.6030917165331 34.5409464858601 0.8570434434578 0.39283512878744 -156.189915697565 68.4578837330447 -2.28154753229936 0.0239721426271287 DDB2 ts 1 1 1 0.8570434434578 -2.28154753229936 1.59759886172691e-06 320.537587971849 71.0321089550552 4.51257315441198 1.31422161869685e-05 -125.862284069098 140.780967254292 -0.894029118593518 0.372787840924203 ACP2 other 0.0143128882022113 1 0.131895281652416 4.51257315441198 -0.894029118593518 0.0111593734369893 5.58440937350549 4.8498632183066 1.15145708695994 0.251317293728136 -27.198350071736 13.3181913397305 -2.04219547369007 0.0428270506284479 PIWIL4 other 1 1 1 1.15145708695994 -2.04219547369007 1.15543132171263e-16 877.579019097655 126.785430870413 6.92176548261784 1.13007604190068e-10 -699.438959987014 318.960178953826 -2.19287235880397 0.029816679524508 PUM1 other 1.58825589482619e-12 1 1.4700029153044e-06 6.92176548261784 -2.19287235880397 0.498545361084354 -3.93901381172771 3.53345698788232 -1.11477621638985 0.266729241490985 -8.39230580383528 9.53376112529137 -0.88027229689781 0.380119976311775 SPOCD1 other 1 1 1 -1.11477621638985 -0.88027229689781 4.75501824381551e-07 258.542875700319 92.4332781723866 2.79707569408217 0.00584248919322173 -793.780425409827 256.00848706389 -3.10060199376019 0.00231273114358498 YARS essential 0.00446020711269895 1 1 2.79707569408217 -3.10060199376019 3.09124803055741e-05 162.900050487777 48.0245287008026 3.39201768126992 0.00088452615506574 -371.019055064249 190.557021341156 -1.94702379609519 0.0533753223105837 CDCA8 essential 0.241951983351729 1 1 3.39201768126992 -1.94702379609519 1.54998513302832e-12 426.080741356004 61.402451644694 6.93914868125339 1.06654435256184e-10 -384.092705330532 243.639419375743 -1.5764801373877 0.116994189469753 GNL2 essential 1.95654623342165e-08 1 1.38896071034129e-06 6.93914868125339 -1.5764801373877 5.71527249298279e-08 121.546715567243 24.6437033576619 4.93216112055874 2.1600008153039e-06 -119.064556309055 85.9885166886939 -1.38465647384181 0.168241472658076 AGO4 other 0.000579585783513385 1 0.0231141687245671 4.93216112055874 -1.38465647384181 8.98494234206864e-11 181.490334037674 31.540985630333 5.75411105298925 4.47684437126648e-08 -276.522239206343 98.953239159101 -2.79447385003476 0.00585098569500254 HOOK1 other 1.06615325830987e-06 1 0.000529476383789687 5.75411105298925 -2.79447385003476 0.0499203630586348 12.0615249741491 14.4495628327591 0.834732864499125 0.405144621101063 -90.9871270362214 45.3324783027514 -2.0071068347194 0.0464654244390005 CYP2J2 other 1 1 1 0.834732864499125 -2.0071068347194 1.27652752670317e-09 414.742708384742 94.5153587616369 4.38809854629767 2.13636791211597e-05 -1042.96385036767 293.407863926258 -3.55465540838331 0.00050562120563068 BTF3L4 other 1.43315745422965e-05 1 0.210111784156606 4.38809854629767 -3.55465540838331 8.77300467565994e-15 416.420840941619 51.841994619648 8.03250036957097 2.52059354747388e-13 -193.14985441445 160.93520780457 -1.2001715289609 0.231952276489451 ZCCHC11 other 1.17189796457466e-10 1 3.4499363884275e-09 8.03250036957097 -1.2001715289609 2.42971128795331e-13 238.823520702759 46.7590078552513 5.10754037900182 9.70871756282307e-07 -676.575153399465 145.155885708694 -4.66102459501538 6.86194965458304e-06 PRPF38A essential 3.13942995516447e-09 0.0997727479776374 0.0106193952702159 5.10754037900182 -4.66102459501538 1.18362726080679e-18 1010.5453191284 101.643077342958 9.9420968505182 3.7196757380672e-18 365.11930547455 392.765537244337 0.929611360600134 0.354086098229477 DSC2 other 1.65838015511639e-14 1 5.29012283467918e-14 9.9420968505182 0.929611360600134 7.02763462642961e-15 163.680832938033 27.4572068195566 5.96130677143204 1.75815230508197e-08 -167.299626320222 71.7504220636747 -2.33168839302092 0.0210658324895153 RNF138 other 9.40156960323753e-11 1 0.000211716700577971 5.96130677143204 -2.33168839302092 7.36262931640251e-30 561.996964245559 46.1009090710657 12.190583126663 2.83309033081505e-24 51.1308265604422 117.882188710082 0.433745140974542 0.665088506123234 ELP2 essential 1.0666977353604e-25 1 4.08899927446536e-20 12.190583126663 0.433745140974542 0.000377584793214259 180.154873793332 44.9872933649474 4.00457240963295 9.82803096115448e-05 161.772777056111 174.12112164385 0.929081868579988 0.354369774309032 DSC3 other 1 1 0.900149355732139 4.00457240963295 0.929081868579988 0.000112262595092678 14.8045213528532 3.41809787792151 4.33121633189031 2.72109581713267e-05 14.0098256832871 13.2080913375511 1.06070024239283 0.290554042042358 DSC1 other 0.818955631201084 1 0.264735412048838 4.33121633189031 1.06070024239283 2.97463021321867e-10 179.142690951305 26.5975807323504 6.73530020470679 3.32686695849416e-10 133.344297678683 68.2177745268711 1.95468554351856 0.0524920364326154 DTNA other 3.44878626920572e-06 1 4.26005314035178e-06 6.73530020470679 1.95468554351856 0.277607304914978 -4.40983943772001 14.4983712132011 -0.30416102421938 0.761423967718067 -53.4472030452981 36.7574731620568 -1.45404997807274 0.148007809485741 FHOD3 other 1 1 1 -0.30416102421938 -1.45404997807274 7.07366096734139e-21 1366.53250887096 147.88053380346 9.24078696312488 2.14497009147328e-16 215.697178865074 333.243104699309 0.647266742577318 0.518442115433067 TPGS2 other 1.0043891207528e-16 1 3.02097587683097e-12 9.24078696312488 0.647266742577318 0.151124559000464 405.458909137332 241.897850987996 1.67615754948337 0.0958185438734134 -409.316554431433 873.45887001497 -0.468615716758841 0.640033823038763 SLC43A3 other 1 1 1 1.67615754948337 -0.468615716758841 0.0297545947572655 47.5518782114702 36.0331431304583 1.31967056105287 0.188982752883585 -239.619449143076 130.110574993821 -1.84166005841151 0.0675266060887113 TIMM10 essential 1 1 1 1.31967056105287 -1.84166005841151 1.43727493598324e-13 263.152547539018 56.7037667503095 4.64083010036687 7.27647786141061e-06 -333.261067177701 109.223868984416 -3.05117434747941 0.0026770319876687 DHX34 other 1.86802623429742e-09 1 0.0747148746809641 4.64083010036687 -3.05117434747941 0.310536583920773 -14.1528093234539 9.89059445831301 -1.43093616699232 0.154501210513853 -31.9023792679749 32.7478144415476 -0.974183462683233 0.331513249646457 TCN1 other 1 1 1 -1.43093616699232 -0.974183462683233 0.360561556096963 -1.43390341984547 4.35586173201394 -0.329189379292464 0.742451281609173 -11.1150097334582 8.39034332986574 -1.32473836844005 0.1871829176 C5AR2 other 1 1 1 -0.329189379292464 -1.32473836844005 2.22992896373602e-07 128.337363118702 171.411029135661 0.748711233844422 0.455211541072835 -1268.78090232151 301.083563805526 -4.2140490376985 4.32872700656021e-05 TMEM165 other 0.00215388838607262 0.623466550754867 1 0.748711233844422 -4.2140490376985 7.27506958945044e-11 278.416907577748 52.1113204267714 5.3427336958193 3.36150509228048e-07 -88.0749452474814 91.5335620340191 -0.962214768990939 0.337500680004773 CLOCK other 8.66242536015864e-07 1 0.00378337398136168 5.3427336958193 -0.962214768990939 0.0968800742826047 69.933582716238 82.6559098290269 0.846080853273469 0.398921219347204 302.562242780503 142.722543761263 2.11993308700137 0.0357385209488264 PDGFRA other 1 1 1 0.846080853273469 2.11993308700137 0.000204970311231268 39.1630799674901 9.72718553884026 4.02614711224676 8.84821564003055e-05 8.72211032191951 19.2039323410434 0.454183558191269 0.6503320705659 GGACT other 1 1 0.814124321039211 4.02614711224676 0.454183558191269 0.000189846052046397 2736.7616547281 662.489116013118 4.13102885553505 5.90657401404165e-05 3503.44455804729 1349.80647156532 2.59551619572877 0.0103582611033327 COL4A2 other 1 1 0.553741313816404 4.13102885553505 2.59551619572877 0.361352933347733 -360.594771241829 254.109046250497 -1.41905523066802 0.157957523060261 -208.919325900294 473.340380270534 -0.441372286431357 0.659579069420544 CLDN10 other 1 1 1 -1.41905523066802 -0.441372286431357 0.133809960067084 95.4772248686846 57.8035733252982 1.65175298646975 0.100662975588134 -35.4815428963515 107.962511260322 -0.328646883831717 0.742877938156865 DZIP1 other 1 1 1 1.65175298646975 -0.328646883831717 2.66706660175894e-10 382.857900585017 62.5784674565771 6.1180453300599 7.59287137304607e-09 -90.243347325634 128.543866301116 -0.702043200678573 0.483718836793152 UBAC2 other 3.09913139124388e-06 1 9.28760026350996e-05 6.1180453300599 -0.702043200678573 3.68834728163598e-05 342.553613445378 91.395895950905 3.7480196444421 0.000252138008352932 -193.428881706529 181.008580396947 -1.06861719639116 0.286925294732434 ARGLU1 other 0.285404312652992 1 1 3.7480196444421 -1.06861719639116 1.34553535256436e-07 105.350613627744 19.3729601252778 5.43802356204115 2.07231409104561e-07 1.30231650571286 38.7228503346964 0.0336317315088233 0.973214369489913 BIVM other 0.00132521776874064 1 0.00236305975801931 5.43802356204115 0.0336317315088233 0.000652200295418645 85.4102454353615 32.9421888234528 2.59273134196094 0.01043888989028 -108.66156608438 65.8451490768027 -1.65025924624509 0.1009279915478 ERCC5 other 1 1 1 2.59273134196094 -1.65025924624509 7.83647970404122e-08 179.605980294839 36.5941330980165 4.90805397176013 2.30825648979096e-06 -85.4441981566966 72.2461037971766 -1.18268243774879 0.238746003285284 TPP2 other 0.000786469103097577 1 0.0246429462850082 4.90805397176013 -1.18268243774879 0.0466011019630868 31.2739028152117 12.5046767852488 2.50097650281566 0.0134245023042894 24.7166716001682 24.9554154941728 0.990433182967427 0.323506048741554 KDELC1 other 1 1 1 2.50097650281566 0.990433182967427 2.49555392280476e-05 131.487576297351 45.5815771931385 2.88466491056709 0.0044803309986789 -215.544980406128 91.2516439142457 -2.36209421726898 0.0194223911712435 CARS2 other 0.197822559460733 1 1 2.88466491056709 -2.36209421726898 0.000331193621432822 177.073274431042 52.3517658408713 3.38237443545409 0.00090984070451638 -147.827365338773 145.734580174565 -1.01436025109278 0.311991658786523 ARHGAP32 other 1 1 1 3.38237443545409 -1.01436025109278 3.95822327643155e-15 885.454000401939 112.155185268075 7.89490025169602 5.08449714519031e-13 -607.698501663578 311.853941343098 -1.94866384900038 0.0531532149247363 STT3A other 5.31906043886872e-11 1 6.93525410603958e-09 7.89490025169602 -1.94866384900038 0.00189885052840701 17.2051187437241 5.84895177631812 2.94157302055148 0.00377013668350819 -15.2991216714858 16.2818512921293 -0.939642636269588 0.348872379098866 ADAMTS8 other 1 1 1 2.94157302055148 -0.939642636269588 0.299786286633604 57.7242967337317 40.5038571334789 1.42515554860623 0.156135815940626 -10.6538716839477 112.195034002115 -0.0949584959682517 0.924471239027568 ETS1 other 1 1 1 1.42515554860623 -0.0949584959682517 0.443528620314378 13.8234511996599 16.4547550036642 0.840088545625966 0.402186932792295 51.3613449644752 43.6624485615984 1.17632763751248 0.241315121919239 SLC37A2 other 1 1 1 0.840088545625966 1.17632763751248 2.94454243196502e-07 491.572458600505 131.494508853473 3.73834970666549 0.000261742359529592 -259.129140328889 198.265016015071 -1.30698368041486 0.193192070271438 TMED7 other 0.00280997684282422 1 1 3.73834970666549 -1.30698368041486 1.87345261383247e-12 178.583706008166 30.39216374679 5.8759786731877 2.48518917721193e-08 -26.075296519541 45.7589641185061 -0.569840183707207 0.569611085777992 APC ts 2.35830215029232e-08 1 0.000297377736945179 5.8759786731877 -0.569840183707207 0.00508856355642671 1083.32542464276 359.22548083063 3.01572544948039 0.00299098724395429 480.729307090861 543.143305498698 0.885087420251768 0.377463016047416 NREP other 1 1 1 3.01572544948039 0.885087420251768 8.48351197836799e-19 246.642899651599 34.3547983450483 7.1792853264455 2.68301549145268e-11 -68.7298891995754 51.7188281753603 -1.32891427792093 0.18581669857563 WDR36 other 1.18955804960676e-14 1 3.54801968589702e-07 7.1792853264455 -1.32891427792093 0.000360833332540662 -58.3733054140401 39.3417344080819 -1.48375017757348 0.139905825246505 -233.740847077109 57.3383061703747 -4.0765216604511 7.28348651020581e-05 OSTF1 other 1 1 1 -1.48375017757348 -4.0765216604511 0.00162484846032098 71.9881000275269 78.4649709792741 0.917455255881532 0.360320352285878 -320.991022084825 113.743248795228 -2.82206658843291 0.00539306254957775 RFK other 1 1 1 0.917455255881532 -2.82206658843291 3.87393642956486e-06 373.37257124817 156.32435708656 2.38844782864788 0.0181388820123868 -569.272178055851 211.167664793699 -2.69583024755235 0.00780752518468905 UBQLN1 other 0.0333545926585534 1 1 2.38844782864788 -2.69583024755235 1.40059823408712e-14 169.826286919831 25.3074468828704 6.71052626153211 3.54993547011578e-10 -70.828217299578 37.7485332263766 -1.87631707104548 0.0625163438064668 NAA35 essential 1.86321583080609e-10 1 4.54143244691911e-06 6.71052626153211 -1.87631707104548 6.77227346193722e-05 3.73729181181239 18.0144451996056 0.207460833259201 0.835922295076949 -94.7555965980046 24.6967647294708 -3.83676152062671 0.000181060624966125 C9orf40 other 0.507514173237575 1 1 0.207460833259201 -3.83676152062671 0.00169211259231076 834.82016648343 545.585039319083 1.53013757035077 0.128020999593947 -2599.8887231035 1003.68525398114 -2.59034265253073 0.0105024491356658 ANXA1 other 1 1 1 1.53013757035077 -2.59034265253073 0.0292229786297257 133.391342479483 175.196353752866 0.761381955857635 0.447585811545251 -479.105368665039 262.511803779689 -1.82508124117392 0.0699138960420465 CTSL other 1 1 1 0.761381955857635 -1.82508124117392 0.585702988439852 9.91630390091196 45.7498300196266 0.216750617360936 0.828689571179176 -75.3314407119966 84.5635679816133 -0.890826185673433 0.374412058921087 TMEM2 other 1 1 1 0.216750617360936 -0.890826185673433 1.2016841910225e-06 108.170364989651 25.8628612870089 4.1824593106404 4.84034793045336e-05 -28.6809922782997 35.5193991808585 -0.80747402658083 0.420646990526841 AGTPBP1 other 0.0108884604548549 1 0.458816580327674 4.1824593106404 -0.80747402658083 7.34035276037438e-09 866.395611814344 185.743811735438 4.66446555456924 6.69932285525946e-06 -479.639029535865 277.055069258482 -1.73120466923628 0.0854311205700944 GOLM1 other 7.8857409704702e-05 1 0.0690499206691593 4.66446555456924 -1.73120466923628 0.101387914307183 13.2085500717096 15.9166551735528 0.829857148231558 0.407895830755607 -47.6140911868346 29.3694072299697 -1.6212138983264 0.107004275784193 FAM189A2 other 1 1 1 0.829857148231558 -1.6212138983264 0.174710106150493 576.904923334696 395.247895347333 1.45960277113614 0.146423014669648 -164.093024464057 543.782188120634 -0.301762411584643 0.763237679411635 PSAT1 other 1 1 1 1.45960277113614 -0.301762411584643 9.27851767413713e-10 182.33388185654 47.5909570057902 3.83127159713044 0.000185636381786326 -226.47220464135 70.9865688989788 -3.19035288159431 0.00172425517071775 ISCA1 other 1.04902920823794e-05 1 1 3.83127159713044 -3.19035288159431 0.684002793634273 25.8590579938593 30.983434583558 0.834609149741647 0.405239073300408 30.5094772937812 49.4984192166811 0.616372760516348 0.538564520114605 ADAM19 other 1 1 1 0.834609149741647 0.616372760516348 0.733153701977517 6.46229700073157 32.3400970490992 0.199823055290168 0.841884307409221 39.4516459400146 51.2958585326294 0.769100022274104 0.443019582968604 HAVCR2 other 1 1 1 0.199823055290168 0.769100022274104 0.0403073294152414 55.7316241373778 22.9185614279122 2.43172436074033 0.0161742629260615 13.8046728721982 37.4478455852166 0.368637304936118 0.712904366316099 CCNJL other 1 1 1 2.43172436074033 0.368637304936118 0.527625070939802 -23.4517884095615 34.3484552278158 -0.682761080637186 0.495777003707718 -74.8166099196181 66.5111921831083 -1.12487248332047 0.262381970804121 TAOK3 other 1 1 1 -0.682761080637186 -1.12487248332047 8.02885952103367e-16 117.171046046046 21.9187183124132 5.34570700603824 3.16916015614367e-07 -161.520624791458 43.9193211675329 -3.67766669651674 0.000324069194762644 USP30 other 1.09144316328932e-11 1 0.00357291116003637 5.34570700603824 -3.67766669651674 0.0807919471863161 -56.3848903958932 25.0618188663504 -2.24983233246487 0.0258674923018465 -46.9307684525538 50.3487549346237 -0.932113783419112 0.352727350604308 SDS other 1 1 1 -2.24983233246487 -0.932113783419112 3.29811465962556e-06 381.411578166998 93.8300990837586 4.06491714163624 7.61860317852476e-05 -133.320491382999 189.185799557362 -0.704706651846648 0.482050339705566 MSI1 other 0.0285682691816766 1 0.705635026394963 4.06491714163624 -0.704706651846648 0.0842453063311252 -5.5620528711887 15.509495698125 -0.358622419416326 0.720365563384768 -64.6123863447976 31.4337612728189 -2.05550922729278 0.0415077840640684 HNF1A other 1 1 1 -0.358622419416326 -2.05550922729278 3.46489980948388e-08 1574.93286678469 356.616677613736 4.41631860103457 1.87492745189282e-05 -1118.4440694844 691.239134349046 -1.618027704027 0.107689795244649 FBXO21 other 0.000356538190395891 1 0.185392826443162 4.41631860103457 -1.618027704027 0.234649158704207 -19.5150296186295 34.5301547897636 -0.565159054091896 0.572782684941046 -115.996922273536 68.8894283819606 -1.68381310453595 0.0942306293341156 TBX3 other 1 1 1 -0.565159054091896 -1.68381310453595 0.893822044351494 -4.80734914299141 66.1891121218912 -0.0726305126157062 0.942193783362382 -63.1305150590196 143.777337772952 -0.439085297007745 0.661211215250181 OASL other 1 1 1 -0.0726305126157062 -0.439085297007745 0.0154252815875036 33.1281965728036 17.0228089971633 1.94610634345507 0.0534506563948514 -31.2472166131889 32.9957416297098 -0.947007555212928 0.345108973497672 HRK other 1 1 1 1.94610634345507 -0.947007555212928 7.36988233448815e-09 100.390227373313 22.9595706429566 4.37247842890782 2.24323848221881e-05 -91.0744910378402 44.5031170231837 -2.04647442987859 0.0423991965256801 RNFT2 other 7.91672760370717e-05 1 0.219949533181555 4.37247842890782 -2.04647442987859 0.000196453742084034 44.2546194834205 46.8158629271305 0.945291119642577 0.345972098081576 -311.050678333976 101.622394769959 -3.0608477495349 0.00259941036970282 P2RX4 other 1 1 1 0.945291119642577 -3.0608477495349 0.149146115813296 46.0539436607276 43.8730728514929 1.04970864057361 0.295496605691657 -74.0213679366118 85.8761979768986 -0.861954414382949 0.390052797322887 BICDL1 other 1 1 1 1.04970864057361 -0.861954414382949 0.0168958133848986 20.6866151385384 15.7341591962196 1.31475822003306 0.190558484551055 -49.2692050382555 31.4087810008288 -1.56864429208365 0.118796695372518 DTX1 other 1 1 1 1.31475822003306 -1.56864429208365 7.90107082331351e-08 129.681527616706 37.630756854884 3.44615783617635 0.00073306279925894 -181.035546116335 74.5674096212803 -2.42781058153683 0.0163431665765259 TRAFD1 other 0.000792477403578345 1 1 3.44615783617635 -2.42781058153683 6.26856040728507e-09 213.322793304259 38.8645202077108 5.48888271781458 1.63011404542255e-07 -195.599274478679 116.838248322747 -1.67410310653038 0.096140124425431 DMTF1 other 6.76377667946059e-05 1 0.00187184328664199 5.48888271781458 -1.67410310653038 2.93871627879777e-09 131.090482603763 22.5265416456598 5.81937896485856 3.31585693652006e-08 -89.5994254323997 67.7214501190757 -1.3230582817535 0.187777107889531 TMEM243 other 3.2361143662121e-05 1 0.000394553816876522 5.81937896485856 -1.3230582817535 0.0101826878434338 352.055707873281 177.050861503757 1.98844391313967 0.0485820348359934 -1102.21962960616 621.751524473177 -1.7727654637278 0.0782972901644054 CCDC146 other 1 1 1 1.98844391313967 -1.7727654637278 5.87023129736697e-06 60.7124325565378 17.1542084361112 3.5392150435069 0.000531822202403715 -149.698733402212 57.9544431249325 -2.58304152935274 0.0107300415428383 TMEM60 other 0.0495506223810746 1 1 3.5392150435069 -2.58304152935274 0.305787150463178 -21.4008995299449 23.7590105291083 -0.900748770817943 0.36914685295403 68.9171936469287 77.1968132378395 0.892746614223547 0.373404079405502 CD36 other 1 1 1 -0.900748770817943 0.892746614223547 4.44789255339951e-09 106.8788000848 20.2787708085208 5.27047724410847 4.58882834769568e-07 -136.692262030952 65.0390005957818 -2.10169684003135 0.0372291011325403 PNPLA8 other 4.84331020139672e-05 1 0.00512526238154131 5.27047724410847 -2.10169684003135 0.000891321835773986 116.14028986597 30.2992291170687 3.83311038763505 0.000183120156520115 94.7809045205141 106.645086783082 0.888750784302895 0.375505389790422 HILPDA other 1 1 1 3.83311038763505 0.888750784302895 1.20747479488409e-06 66.4841930453449 16.9518454349238 3.9219442685795 0.000131609965864819 -121.695050327075 52.9874332596411 -2.29667758637719 0.0229761909189425 RINT1 essential 0.01093730669206 1 1 3.9219442685795 -2.29667758637719 3.45435770686807e-13 383.657522750086 49.9421904180175 7.68203235658793 1.70193347880219e-12 -85.8007865852654 155.471162513912 -0.55187589259576 0.581833350474853 SRPK2 other 4.44541293296853e-09 1 2.30339677021089e-08 7.68203235658793 -0.55187589259576 0.000154499957043532 125.801128403196 34.8670581396663 3.60802244626652 0.000415763703683646 -187.921529276636 122.763863635618 -1.53075606869474 0.127868063833574 KCP other 1 1 1 3.60802244626652 -1.53075606869474 1.02750013862061e-06 334.920941107702 88.868069893201 3.76874327877493 0.00023477697803829 -664.758691695562 272.296606172079 -2.44130362489889 0.0157901908128493 TES other 0.0093677187638041 1 1 3.76874327877493 -2.44130362489889 0.637256459947157 -22.6660975452612 31.0625067510769 -0.729693122544767 0.466708219596056 32.2144513884416 96.3946551739969 0.334193336033963 0.738697370200302 MDFIC other 1 1 1 -0.729693122544767 0.334193336033963 1.27104008564608e-11 86.4479931282212 16.5121279475017 5.23542413207262 5.50736962725869e-07 -57.3287932465867 31.5266183128768 -1.81842507425451 0.07100748858877 MTO1 other 1.55668157134726e-07 1 0.00611758618195895 5.23542413207262 -1.81842507425451 0.231360885061422 107.445638786451 81.638957942419 1.31610742584727 0.190159137550765 -17.1367307146783 162.098690792104 -0.10571788477093 0.915948380817364 ANKRD6 other 1 1 1 1.31610742584727 -0.10571788477093 0.000364427769098412 41.0653990317039 13.9168594760193 2.95076623447017 0.0036828965807942 -19.000875412019 26.5714702677547 -0.715085586930325 0.475675120191618 KHDC1 other 1 1 1 2.95076623447017 -0.715085586930325 1.07644761085391e-09 62.2103126772547 10.1894365916779 6.10537315949973 8.18901905862194e-09 15.1371064946114 19.6490609644329 0.770373023016791 0.442274361928124 CEP162 other 1.21315645743236e-05 1 0.000100020678782008 6.10537315949973 0.770373023016791 1.63918225927391e-15 937.333549158282 139.732120343027 6.70807504285508 3.7146506841263e-10 -349.660865481765 272.363665663518 -1.2838014374272 0.201177921557078 SYNCRIP other 2.21797751502352e-11 1 4.74843796951865e-06 6.70807504285508 -1.2838014374272 1.55530540916948e-09 273.865989386709 48.5424155670765 5.64178741802162 8.0722110243257e-08 12.810946292471 94.358722519494 0.135768543176539 0.892185087325409 SNX14 other 1.73836485582873e-05 1 0.000941865582318323 5.64178741802162 0.135768543176539 0.0851896465628903 -124.08032979557 90.700312070883 -1.36802539001851 0.173336463640972 -394.178648764157 176.306957104389 -2.23575209531164 0.0268345879899115 NT5E other 1 1 1 -1.36802539001851 -2.23575209531164 0.00789624193201362 48.1745387996002 17.9855670138997 2.67851098396674 0.00820893145942494 2.28182060569555 34.1606776303147 0.0667967020557762 0.946831328761546 MRAP2 other 1 1 1 2.67851098396674 0.0667967020557762 7.14674221620629e-07 59.1007543410669 10.6628154734816 5.54269690665196 1.29512145643977e-07 82.4487188947511 21.5230263181369 3.83072146435437 0.000186888825321065 EPHA7 other 0.0065964430655584 1 0.00149638333077051 5.54269690665196 3.83072146435437 1.77869972900116e-17 428.391382148736 56.1657965957447 7.62726442272508 2.49334341450187e-12 -96.245830649202 111.176942782422 -0.865699561801757 0.388028298056777 AKIRIN2 essential 2.4668786541517e-13 1 3.36601360957752e-08 7.62726442272508 -0.865699561801757 1.97805988754315e-12 247.241305970531 39.5190464298905 6.25625687626734 3.86541211665738e-09 -37.4555558963976 78.2256645512388 -0.478814160432779 0.63276345687687 ORC3 essential 2.48859714451803e-08 1 4.78151478830518e-05 6.25625687626734 -0.478814160432779 0.00033654798190081 55.5349891060945 13.8088338421085 4.02170014796953 9.10026455196962e-05 40.4305664830842 26.634408327976 1.51798252790985 0.131109696664089 LCA5 other 1 1 0.836496317617047 4.02170014796953 1.51798252790985 4.64535753617587e-13 304.877696323291 46.0835082738996 6.615765763996 6.22975519519666e-10 -13.3871448873631 92.0711589903528 -0.145399982298103 0.884591586665442 MAP3K7 other 5.95860011165279e-09 1 7.9161499265364e-06 6.615765763996 -0.145399982298103 0.0130730887539011 83.6289445758972 41.0900348513158 2.03526097942016 0.0435393590197986 -65.8035104106925 68.5761873847573 -0.959567933421142 0.338776830446331 PRR5L other 1 1 1 2.03526097942016 -0.959567933421142 0.564267432556446 -30.6181235870384 36.6645246629228 -0.835088518630138 0.404961531568548 -60.2404860587792 60.9097967904974 -0.989011443692378 0.32420891546318 LMO2 other 1 1 1 -0.835088518630138 -0.989011443692378 1.23392419041781e-55 505.388909913952 18.9561844253028 26.660898552947 2.71084528412329e-56 114.91934276889 123.973695081397 0.926965536466727 0.355562776884284 PHF21A other 1.80115914075287e-51 1 3.95783411482e-52 26.660898552947 0.926965536466727 3.07184960883105e-09 170.373229688 83.9465340693784 2.02954453780299 0.0441136381135435 -645.215805026089 139.338217690854 -4.63057311711572 7.6672418632605e-06 NAT10 essential 3.37934175467504e-05 0.111428025998765 1 2.02954453780299 -4.63057311711572 0.000429124604185335 28.4727399813607 198.680437601991 0.143309227244602 0.886230913965231 -1178.49638863001 335.93885531324 -3.50806812010816 0.000589904982037154 EHF other 1 1 1 0.143309227244602 -3.50806812010816 0.011989464346492 -54.6732402740802 73.2710775617849 -0.746177647353114 0.456697637761336 -344.768135228494 118.843387782392 -2.9010291751341 0.00426449737818496 PRRG4 other 1 1 1 -0.746177647353114 -2.9010291751341 7.06872437993977e-08 862.428679082783 323.482846025828 2.66607237347579 0.00849350343138676 -1885.26917590699 537.393423146435 -3.50817314597702 0.000591643409030631 CAPRIN1 other 0.000712527417497929 1 1 2.66607237347579 -3.50817314597702 0.00135806334038528 591.96316254417 433.474159239587 1.36562503191104 0.174231232004718 -3307.28296819787 1160.19724974317 -2.8506212792092 0.00501874067566278 ATP5G2 other 1 1 1 1.36562503191104 -2.8506212792092 9.74723287325266e-17 275.755582937425 35.2374190114558 7.82564644838989 1.22680442656122e-12 -291.143471964635 96.7731472783498 -3.00851507006604 0.00312508406147475 DNAJC14 other 1.34121924335957e-12 1 1.66330144153171e-08 7.82564644838989 -3.00851507006604 0.0366112722912412 -164.840011420958 588.42689855585 -0.280136771152912 0.779777408992184 -3963.25231750262 1561.42225354967 -2.53823224851109 0.0122122244919117 CD63 other 1 1 1 -0.280136771152912 -2.53823224851109 0.00120645694326038 55.684670419892 15.5204120949454 3.58783452908618 0.000453390893735012 14.0255232361143 41.9180144890461 0.334594169286798 0.738408169780522 PRPH other 1 1 1 3.58783452908618 0.334594169286798 0.627922816807794 -9.5118026925463 17.3782104100782 -0.547340748448417 0.584969074908891 35.3924842205114 56.2813014263102 0.628849783561797 0.530416776617711 AVIL other 1 1 1 -0.547340748448417 0.628849783561797 0.65317268421529 -0.351725557058001 11.3258176860012 -0.0310552020886523 0.975269431260157 -26.4609912399318 30.0516806001076 -0.880516187831341 0.380078091743137 AMHR2 other 1 1 1 -0.0310552020886523 -0.880516187831341 1.20660997301107e-07 567.050340272217 106.365897467539 5.33112918494644 3.75283341230204e-07 -214.981024819856 286.62270849471 -0.750048821842824 0.454466230010349 GDF11 other 0.00119237197532954 1 0.00421180493862658 5.33112918494644 -0.750048821842824 0.000223426477334457 43.7844665223378 12.5332289168117 3.49347058231791 0.000646534729400886 -30.6168966264741 32.5685515429298 -0.940075476986345 0.348870377860998 GLS2 other 1 1 1 3.49347058231791 -0.940075476986345 8.31122553661351e-07 366.381483664044 71.2247315746525 5.14402056089225 8.64379197552397e-07 -60.5651237163105 190.231416192379 -0.318376033404817 0.75066099787309 ITGA7 other 0.00763386065537951 1 0.00948051103875469 5.14402056089225 -0.318376033404817 0.126805564799829 1.3172192200964 2.20309134538092 0.597895871570702 0.55081104133531 12.9395517907275 6.32941980285414 2.04435038183004 0.0426677381631895 TESPA1 other 1 1 1 0.597895871570702 2.04435038183004 1.58758386023515e-07 10.268366765804 2.03542733601967 5.04482109682383 1.31152245335014e-06 -4.68162866403706 5.28948219221827 -0.88508260240001 0.377547787577802 FAM186B other 0.00155440335755623 1 0.0142247725290356 5.04482109682383 -0.88508260240001 0.0631441037470792 85.273976367774 54.8792301577116 1.55384789696784 0.122415772089598 -174.392920114877 146.574840531436 -1.18978754800334 0.236087874805656 RDH5 other 1 1 1 1.55384789696784 -1.18978754800334 0.000953357275909487 45.463543972734 11.8774689757658 3.82771313193875 0.000197095343819684 40.592278729093 40.457917445895 1.00332101333139 0.317500977288714 AGAP2 other 1 1 1 3.82771313193875 1.00332101333139 0.0496225224562701 56.6671294042563 100.514744961322 0.563769319875027 0.573788063224822 -562.811210051033 268.460994649966 -2.09643568811498 0.0377924836055825 BLOC1S1 other 1 1 1 0.563769319875027 -2.09643568811498 1.6907302809705e-06 712.89378790531 157.454130199411 4.52762837661006 1.29704797052606e-05 -876.403350254503 536.331958780152 -1.63406885587765 0.104574299317498 CDK4 essential 0.0151049843301904 1 0.130262527679932 4.52762837661006 -1.63406885587765 0.838772033521588 6.22356485242262 40.2064477214973 0.154790219109435 0.877199030463074 -56.1508146042069 114.405944861729 -0.490803294112652 0.624297457775026 PPP1R1A other 1 1 1 0.154790219109435 -0.490803294112652 0.000368281210978946 125.46111893033 57.5140313076829 2.18140019187928 0.0307430852311343 -369.734635233403 155.33569488558 -2.3802297051283 0.0185841694014003 TROAP other 1 1 1 2.18140019187928 -2.3802297051283 8.60115134060476e-07 353.778967636974 82.1526823273736 4.30635930093171 3.16966248604323e-05 -623.314685722719 279.834571350283 -2.22743988605498 0.0275735889503038 TSPAN31 other 0.00788725577933457 1 0.306538059025241 4.30635930093171 -2.22743988605498 0.0750506162918295 86.8526905887968 41.6860108368918 2.08349728950156 0.0391058880212092 -51.2570555820716 142.00631760228 -0.360949121472387 0.718705895769864 B4GALNT1 other 1 1 1 2.08349728950156 -0.360949121472387 2.65108831330718e-08 179.568024986663 38.1059436818276 4.71233638736253 5.43482727163028e-06 -201.488620915145 97.052112896682 -2.0760869073468 0.0395479013761431 TFCP2 other 0.000275182966921285 1 0.0564841598340535 4.71233638736253 -2.0760869073468 5.36062738921475e-06 34.6027775585892 6.98636754071603 4.9528996802597 2.17917586248971e-06 9.04122938530736 18.8946509233059 0.478507352266315 0.633074810595043 COQ10A other 0.045431317123595 1 0.0233128233769149 4.9528996802597 0.478507352266315 0.45884366352827 -59.8125810840743 66.816821097184 -0.895172504496702 0.372119610137286 -196.768186564567 170.115978930369 -1.15667080659781 0.249233492390193 FAIM2 other 1 1 1 -0.895172504496702 -1.15667080659781 1.14554908415956e-11 500.255454459046 69.4410761983775 7.20402795932957 4.01280289775423e-11 -36.8704841399452 180.443856800096 -0.204332166213849 0.838408646979765 PAN2 other 1.40639061062269e-07 1 5.28606525721165e-07 7.20402795932957 -0.204332166213849 4.25103778904415e-05 212.463495753199 56.5494981485708 3.75712433724875 0.000250190632953174 -207.368519634705 150.050488829785 -1.38199162996357 0.169144426174254 ESPL1 essential 0.326182129553357 1 1 3.75712433724875 -1.38199162996357 0.916977006613258 395.956560261866 1082.20787919487 0.365878467412793 0.714957869128136 938.387104957746 2993.48990185313 0.313475954729907 0.754343265794326 KRT7 other 1 1 1 0.365878467412793 0.313475954729907 6.60175779131805e-11 63.1740499199444 10.1811285179912 6.20501448423019 7.00698095742437e-09 -46.3705755302755 28.2031520747716 -1.64416287255193 0.10259648590707 ZC3H10 other 7.87457669348417e-07 1 8.59055865380228e-05 6.20501448423019 -1.64416287255193 0.00234137936519803 486.661858602886 200.09658028544 2.43213481164275 0.0162460544578944 -984.786637867455 579.969219748575 -1.69799810806231 0.0916831247212087 HNRNPA1 other 1 1 1 2.43213481164275 -1.69799810806231 0.0482433698879308 25.4930029938821 12.1185442378532 2.10363575801891 0.0372791990611338 -29.111808044431 41.2826703099848 -0.705182291403033 0.481920786083591 SLC26A10 other 1 1 1 2.10363575801891 -0.705182291403033 5.59614600867831e-10 459.095202332088 74.0505021114837 6.19975812778307 4.96130677091788e-09 -152.158004180567 192.557269288905 -0.790196104995005 0.43062834935769 ACVR1B other 6.39863334632278e-06 1 6.11332220312502e-05 6.19975812778307 -0.790196104995005 1.27608784540831e-17 1579.17363995314 161.800439284367 9.76000835929572 2.50158984406754e-17 -219.172997787131 551.184536680827 -0.397639961213293 0.69152832971884 OS9 other 1.7723584084876e-13 1 3.54225121919964e-13 9.76000835929572 -0.397639961213293 0.000115812182230602 4.74889462048638 1.93184129709228 2.4582219189714 0.0152486853735391 -12.2838983050847 4.91224898506077 -2.50066687222956 0.0136107966462289 MIP other 0.843112686638786 1 1 2.4582219189714 -2.50066687222956 0.00108137428308174 93.399101436436 35.5001683195857 2.63094812947427 0.00941600702051921 -137.677782699487 92.2545869480182 -1.49236788385453 0.137731328045679 KCNH3 other 1 1 1 2.63094812947427 -1.49236788385453 2.11451195216406e-22 149.774040328004 17.9303277321393 8.35311225569745 3.61634574372218e-14 -78.6313066047451 36.7602025346417 -2.13903355213142 0.0340093924976565 LTV1 essential 3.02036887247115e-18 1 4.9945351066547e-10 8.35311225569745 -2.13903355213142 2.26580312341286e-17 273.055825140798 38.4796216822539 7.09611511764748 4.39504777335429e-11 -129.571236850371 78.6282070634745 -1.64789763991149 0.101412467068374 MAP7 other 3.13881706686384e-13 1 5.78036683151557e-07 7.09611511764748 -1.64789763991149 2.73319542872941e-11 1143.25644896502 333.133229106913 3.43182951766758 0.000780076938177611 -2323.52140613847 693.714811428674 -3.34938993352799 0.00103071210247482 CD164 other 3.30825974693408e-07 1 1 3.43182951766758 -3.34938993352799 2.94901713010699e-15 17.2178716346296 3.17262421423131 5.42701261542295 2.23464675714838e-07 -16.399658403183 6.5996957366525 -2.4849112834255 0.0140493389392727 AFG1L other 3.97055666397605e-11 1 0.00254363429484563 5.42701261542295 -2.4849112834255 0.0150052344628985 55.7037239307778 68.2019860691907 0.816746360938324 0.415335053281151 -251.251464583225 136.875783954515 -1.83561662497377 0.0683432090133345 NHSL1 other 1 1 1 0.816746360938324 -1.83561662497377 2.37537180101482e-11 120.789640427437 18.5903394915353 6.49744134486817 1.07125128457096e-09 17.7148155276437 37.8530093170845 0.467989622152667 0.640453647506865 AHI1 other 2.88132599463098e-07 1 1.35031224420169e-05 6.49744134486817 0.467989622152667 9.29947415299183e-05 325.336134675863 78.280310134794 4.1560404412764 5.43936314545468e-05 209.091810037263 151.424308261577 1.38083384654509 0.169397720252756 HEY2 other 0.684787285978891 1 0.512279221038922 4.1560404412764 1.38083384654509 0.112206964038034 -16.7323177366703 19.1602703931177 -0.873281921046401 0.383896073802107 -76.2285092491839 37.0668452056338 -2.05651462449245 0.041454173047513 PKIB other 1 1 1 -0.873281921046401 -2.05651462449245 1.68415457571274e-07 64.2836464331791 21.2304256690753 3.02790190998459 0.00292901831307333 -101.082896724252 44.0313459065381 -2.29570308704196 0.0231677126440081 SMPD2 other 0.00164508218955621 1 1 3.02790190998459 -2.29570308704196 0.00853318742007008 49.9164033691418 25.4422070597989 1.96195256377794 0.0517514895505114 -43.5828287352922 52.8310646583689 -0.824947008301267 0.410805065978837 MICAL1 other 1 1 1 1.96195256377794 -0.824947008301267 1.21470411379082e-25 402.289765444758 40.4788732173333 9.93826491376974 2.7329712242868e-18 -101.752210971546 80.7000253747079 -1.26086962797208 0.209262694790306 REPS1 other 1.75172480249774e-21 1 3.88901805216011e-14 9.93826491376974 -1.26086962797208 0.437822530410661 -4.50173789895579 5.3523271539871 -0.84108048133835 0.401606925891881 3.53416106049202 10.9731753457891 0.322072777397861 0.747834344762686 STX11 other 1 1 1 -0.84108048133835 0.322072777397861 0.000550578810011841 80.7274903332723 23.6856213248004 3.40829101446223 0.000835674520314361 4.25833179893206 44.5808541569084 0.0955192958830327 0.924027356654351 TEC other 1 1 1 3.40829101446223 0.0955192958830327 8.41959769736742e-21 169.385083285145 15.0905079345516 11.224611127722 8.34738794522157e-22 172.579158921016 81.4998624736962 2.1175392655014 0.0357995761590558 KCNMB4 other 1.19507769716433e-16 1 1.20077175592012e-17 11.224611127722 2.1175392655014 2.06986476917489e-07 606.399748546874 134.822665179332 4.49775820512289 1.37282082928012e-05 -873.781774225247 412.751268837579 -2.11696932316176 0.0359235919352612 GNS other 0.00200735485314581 1 0.137405636802647 4.49775820512289 -2.11696932316176 0.105922832978084 28.2227198672986 39.9905771849412 0.705734246764662 0.481440772436155 -623.757669174316 333.813993811468 -1.86857855194232 0.063618738628894 CPM other 1 1 1 0.705734246764662 -1.86857855194232 4.1393314231608e-61 519.435230160665 18.7067100472319 27.7673213969299 3.34758905428724e-61 -122.056458582384 156.150824306957 -0.781657472024921 0.435639789307653 MDM2 og 6.04632140981098e-57 1 4.88982333159737e-57 27.7673213969299 -0.781657472024921 1.02140163286422e-13 269.836325702473 41.9492623781289 6.43244506351934 1.48157395945659e-09 -20.6672584411606 77.1995193486933 -0.267712268360261 0.789276717341045 KLHL36 other 1.3322141497448e-09 1 1.85981979130586e-05 6.43244506351934 -0.267712268360261 0.296323318591339 -16.4037129906452 15.2957560731748 -1.07243557704307 0.285191320561439 -44.0421159224612 28.1801535556434 -1.56287707359356 0.120120912710761 BCO1 other 1 1 1 -1.07243557704307 -1.56287707359356 2.68852745539447e-07 38.1593418488851 14.1043783786564 2.70549618171263 0.00758898698934641 -57.4451573540123 26.1228281716068 -2.1990405088087 0.0293662523810523 MPHOSPH6 other 0.00257641586050453 1 1 2.70549618171263 -2.1990405088087 1.61418470707602e-06 20.0313948387343 4.52933094614684 4.42259465623178 1.83411929504531e-05 4.18347261466529 7.99705610249578 0.52312658071258 0.60163804676934 CHST5 other 0.0144501814977445 1 0.181541127823585 4.42259465623178 0.52312658071258 0.934859398638091 4.42408697649504 12.9415476124165 0.341851462359143 0.732925722697273 7.62881862032026 23.8164200910401 0.320317604037825 0.749158985625714 KIAA0513 other 1 1 1 0.341851462359143 0.320317604037825 9.39785827764032e-14 745.114625902069 125.617647569477 5.93160786178519 2.13113887392308e-08 -53.0288858254397 196.045145775037 -0.270493235707508 0.787168123792795 DYNC1LI2 other 1.22726631247705e-09 1 0.000255779287648248 5.93160786178519 -0.270493235707508 4.46355481547047e-05 55.1614308153652 26.66791564087 2.06845677623291 0.0405055184837243 -66.0661859203195 42.7788425595498 -1.54436590537373 0.124840659510647 FBXL8 other 0.341819027768729 1 1 2.06845677623291 -1.54436590537373 0.0014503640446849 123.587649402391 49.4932920596948 2.49705857620725 0.0136986848447029 -14.701195219123 78.0521482059002 -0.188350936611527 0.850878251184167 FHOD1 other 1 1 1 2.49705857620725 -0.188350936611527 2.28173381389905e-17 249.172737955347 32.1310387478248 7.75489208148351 1.25006832500351e-12 43.9433056244651 49.921369240243 0.88025040765591 0.380131793183014 CCDC102A other 3.16065767901296e-13 1 1.69459262137476e-08 7.75489208148351 0.88025040765591 0.000163458066522843 37.6496387332029 11.2484542822799 3.34709443523398 0.00105252903343664 7.47238165980153 17.7390911816671 0.421238133525356 0.674236558497236 SLC9A5 other 1 1 1 3.34709443523398 0.421238133525356 0.447222606941926 12.2923601864181 22.5619796703575 0.544826312496334 0.586641160090866 -63.88210646674 71.2887758260256 -0.896103288723024 0.371560841041402 AGT other 1 1 1 0.544826312496334 -0.896103288723024 7.48506957463776e-07 13.2449261682166 3.06458794093056 4.32192726184089 2.76393016950465e-05 -14.5377317759848 9.57313408051126 -1.5185969039732 0.130914282377367 ZNF670-ZNF695 other 0.0068952460921563 1 0.268792208984327 4.32192726184089 -1.5185969039732 3.93567342776067e-10 222.434432590995 35.547084066683 6.257459322788 3.56280058782331e-09 -93.8591014324989 115.062977951944 -0.815719383446682 0.415896475135188 PCNX2 other 4.53783146220805e-06 1 4.41324108813673e-05 6.257459322788 -0.815719383446682 0.174884388250549 9.2712261166645 27.4044830680733 0.33831056377289 0.735581148418123 -139.956915095534 87.7843791513068 -1.5943259660617 0.112874193887287 KCNK1 other 1 1 1 0.33831056377289 -1.5943259660617 3.29087421117732e-14 157.162513550665 20.6690583447533 7.60375779724668 2.40953264492843e-12 -72.0801509321586 63.7858078675071 -1.1300343029578 0.260174339786494 URB2 essential 4.34395395875406e-10 1 3.25335097718237e-08 7.60375779724668 -1.1300343029578 7.0048776560947e-07 272.539039689532 57.6228581271469 4.72970360283352 4.97341689459322e-06 -209.331110156472 182.525713841867 -1.14685819192483 0.253185024628822 EGLN1 other 0.00647040549093468 1 0.0518528445430289 4.72970360283352 -1.14685819192483 1.89162648971447e-05 114.380908788282 23.8733814366628 4.79114821215169 3.79368630439002e-06 79.850539859897 75.4323938906594 1.05857093672039 0.291410904955006 CAPN9 other 0.151746277004895 1 0.039909579922183 4.79114821215169 1.05857093672039 2.73601221501258e-13 195.422519973369 29.034213788723 6.73076672216527 2.94741022430487e-10 -218.097587274938 91.739004657847 -2.37737032452403 0.0186327848156155 COG2 other 3.53055016225223e-09 1 3.78152731778314e-06 6.73076672216527 -2.37737032452403 0.0214445189309272 40.0649396114126 19.5535457874964 2.04898589988892 0.0421282186017437 -59.8907827177782 60.7597521363698 -0.985698272490623 0.325797817628627 ABCB10 other 1 1 1 2.04898589988892 -0.985698272490623 2.99953533372871e-11 252.045987292985 37.8918287851067 6.65172400947962 4.55666992235139e-10 -113.098647084358 122.652723128589 -0.922104656133769 0.35788883241452 NTPCR other 3.62493845081115e-07 1 5.81157681896696e-06 6.65172400947962 -0.922104656133769 1.69308555778858e-05 77.8352438938028 23.4154438824307 3.32409858572892 0.00110260249559207 -147.807768502899 72.2612989767019 -2.04546237883925 0.0424678434957568 TAF5L other 0.136445765102182 1 1 3.32409858572892 -2.04546237883925 0.0637470402504195 -150.556753980483 65.9123615718506 -2.2841960201405 0.0237174497363048 -264.309450436569 278.068723818263 -0.950518443092913 0.343328649093972 FAM129A other 1 1 1 -2.2841960201405 -0.950518443092913 0.164296030807793 -25.2562132532284 44.9219456618749 -0.562224384565411 0.574759909263141 -195.412860407199 103.899243744749 -1.88079194192475 0.0618403011299078 SP110 other 1 1 1 -0.562224384565411 -1.88079194192475 0.000307822985625316 75.1211662561381 31.290709548255 2.40074985005661 0.0175623138869373 -144.389582856747 72.042343049269 -2.0042321882563 0.046809810407339 MRPL44 other 1 1 1 2.40074985005661 -2.0042321882563 0.0761589706899278 -9.07058439336916 14.9734331447855 -0.605778534933252 0.545559430404361 58.6380431063976 34.2695248591777 1.71108421687655 0.0890921461082809 DOCK10 other 1 1 1 -0.605778534933252 1.71108421687655 5.57673850130173e-11 296.175197753549 41.3883208849197 7.1560090243106 3.57804297302609e-11 84.7001904871721 109.156094508095 0.775954754233997 0.439013915848373 TTLL4 other 6.67089459525713e-07 1 4.71943868142141e-07 7.1560090243106 0.775954754233997 0.00340101681313134 59.997741960228 21.7335932001114 2.76059929013121 0.00649985280156391 -46.2657343663105 57.6934564446645 -0.801923428017964 0.423882973121212 USP37 other 1 1 1 2.76059929013121 -0.801923428017964 0.1020841429247 27.1537950421672 12.8394946602167 2.11486477939848 0.0360203906692497 18.6702274469716 29.9367111207022 0.62365659913993 0.533758170213102 HTR2B other 1 1 1 2.11486477939848 0.62365659913993 0.0537174840792444 1575.49624430645 651.428440546638 2.41852542235397 0.0167202607755116 1244.65115955854 1518.50081116712 0.819657882567677 0.413645892340034 ITM2C other 1 1 1 2.41852542235397 0.819657882567677 0.0629807337786464 -49.718129710222 24.1141422345759 -2.06178304940633 0.0408664231201607 5.03743410112158 54.8799456320609 0.0917900709103237 0.926981107534619 SLC19A3 other 1 1 1 -2.06178304940633 0.0917900709103237 0.363181815948977 -64.9978773095559 262.776813596982 -0.247350123551017 0.804968883178306 704.197319770812 605.005690949675 1.16395156327445 0.246255500404442 SERPINE2 other 1 1 1 -0.247350123551017 1.16395156327445 0.000199564786028305 154.531948296615 61.429613171385 2.51559370666196 0.0130294162788162 -314.605665742145 153.477745514841 -2.0498454983607 0.0422731532977424 DNAJB2 other 1 1 1 2.51559370666196 -2.0498454983607 0.175329178253179 -19.1175073675555 156.238235563527 -0.122361260024486 0.902784710340894 -694.192426838462 391.949075849944 -1.77112913286784 0.0786695207116844 WNT10A other 1 1 1 -0.122361260024486 -1.77112913286784 0.166093078302875 55.9099782865188 29.3332567141633 1.90602696561556 0.0585853397098778 56.9773693968806 78.0612181265882 0.729906229550288 0.466601212748801 CYP27A1 other 1 1 1 1.90602696561556 0.729906229550288 4.81314558960182e-06 223.868463137694 56.8853996962351 3.9354292021 0.000124458883325615 -153.910371910372 125.814378827187 -1.22331305328603 0.223044402180319 EIF4E2 other 0.0409743084042802 1 1 3.9354292021 -1.22331305328603 4.67065683037209e-07 182.228111423461 36.3611970689892 5.01160924591436 1.44072367297934e-06 -1.63535224465461 84.7801787737088 -0.0192893229090684 0.98463479372114 ARMC9 other 0.00438574676371939 1 0.0155871894179635 5.01160924591436 -0.0192893229090684 1.24102934175326e-06 220.271806081128 65.5993036033867 3.3578375681073 0.000984373969125763 -346.504861238337 152.914103121062 -2.26600983274911 0.0248084837126595 CAB39 other 0.0112263514255 1 1 3.3578375681073 -2.26600983274911 0.0653338795963285 520.958409446289 286.362175146322 1.81922912542515 0.0708707178837778 -1589.12320068976 1501.72082717615 -1.05820147921766 0.291664737802501 COX5B essential 1 1 1 1.81922912542515 -1.05820147921766 1.45416016283482e-28 268.375554332201 19.8507443846535 13.5196720652794 7.54471725332788e-28 -115.998654310793 92.0633627726096 -1.25998715251475 0.209605050857093 REV1 other 2.10460600367083e-24 1 1.09353131869734e-23 13.5196720652794 -1.25998715251475 2.90903729563053e-21 79.3795406594358 7.33085298192424 10.8281452179116 1.50197497560105e-20 -45.4509816053408 34.0990660025256 -1.33290986920212 0.18458239658317 TSGA10 other 4.13868736049355e-17 1 2.15428270750459e-16 10.8281452179116 -1.33290986920212 1.47418595459928e-10 66.2138996983478 11.009260104347 6.01438235365182 1.26294125382969e-08 -56.3219659342559 30.6073213343307 -1.84014684980232 0.0676716400407241 MFSD9 other 1.73261075244053e-06 1 0.000152992703488929 6.01438235365182 -1.84014684980232 9.50577722295636e-17 655.529251115052 70.5456196920474 9.29227433222123 1.99056323630771e-16 -390.310678530877 359.692841361361 -1.08512217550295 0.279656061488444 TMEM127 other 1.30809000365102e-12 1 2.80410643098666e-12 9.29227433222123 -1.08512217550295 0.391383311749715 -13.6702867259694 10.482050683824 -1.30416147930533 0.194137107867196 -1.2431341221176 28.7931353603522 -0.0431746701621589 0.965618590704255 EDAR other 1 1 1 -1.30416147930533 -0.0431746701621589 3.03339333326377e-08 116.113426632093 31.3880475904167 3.69928796296155 0.000300337337962442 -319.580467002238 88.5711748412523 -3.60817689925675 0.000416300148251388 TGFBRAP1 other 0.000313501200992811 1 1 3.69928796296155 -3.60817689925675 2.76260213127564e-14 244.244590575603 36.0218363982562 6.78045916025055 2.44917011555533e-10 -289.285176554461 99.6729954543391 -2.90234255763874 0.00425127093869067 GCC2 other 3.65381757882516e-10 1 3.15208193871972e-06 6.78045916025055 -2.90234255763874 6.07677322459973e-11 125.193239017694 20.8083114068184 6.01650160698146 1.24963611176082e-08 -131.746993847875 58.7171464697041 -2.24375675197111 0.0262741043651291 MRPS9 essential 7.256882584817e-07 1 0.000151455896745412 6.01650160698146 -2.24375675197111 1.26993518435111e-09 81.1621034167176 19.8961524796758 4.07928635949216 7.22621769586492e-05 -222.063898210291 56.1432053035251 -3.95531208112815 0.000116286736518982 C2orf49 other 1.42588322498942e-05 1 0.671026575238016 4.07928635949216 -3.95531208112815 3.89356603114773e-25 103.948502193304 8.10774877208198 12.8208834678299 8.83576129256404e-26 38.9658529426153 40.6152448604213 0.959389831983672 0.338927087733542 ANKRD36 other 5.61023929428077e-21 1 1.27747436767891e-21 12.8208834678299 0.959389831983672 2.91061152521574e-09 196.088935797908 34.4583251684496 5.69061133526738 6.15204051580779e-08 -146.589234379991 97.3878985072569 -1.50520995551688 0.134305187369014 EPC2 other 3.20632965617766e-05 1 0.000723172362633206 5.69061133526738 -1.50520995551688 0.365762675644209 18.6917404720874 28.8969739786713 0.646840755225227 0.518710595685896 -62.7117480864024 69.9149627061132 -0.896971773410086 0.371152441292818 ARHGEF4 other 1 1 1 0.646840755225227 -0.896971773410086 1.09558270040332e-09 171.781930299916 75.6461985624635 2.27086005066163 0.0245325186238835 -654.249182472204 151.430399273426 -4.32046131827783 2.77070867720986e-05 ISCU essential 1.23450258681446e-05 0.400367403856824 1 2.27086005066163 -4.32046131827783 0.00709358304782917 57.9645507827845 27.1210971035918 2.13724948372785 0.0341566315568721 -41.7285159830506 54.5600547153792 -0.764818074335403 0.445550294329091 ALDH1L2 other 1 1 1 2.13724948372785 -0.764818074335403 0.00893421229576196 13.8848622121556 8.82031926135046 1.57419043469291 0.117469315818366 -24.7486413527355 17.699415996885 -1.39827446041672 0.16401537241126 USP44 other 1 1 1 1.57419043469291 -1.39827446041672 2.96844124488844e-12 191.32811705593 50.2163312182437 3.81007756668651 0.000199879485217308 -384.376650175142 101.005529916087 -3.80550105023432 0.000203287980141943 SCYL2 other 3.71500421797789e-08 1 1 3.81007756668651 -3.80550105023432 1.92922462479508e-09 708.306324929073 216.355318576333 3.27381055196557 0.00130861615097973 -1358.13464730504 438.018782890777 -3.10063106961259 0.00229447582136215 CKAP4 other 2.14549070523461e-05 1 1 3.27381055196557 -3.10063106961259 0.459002307346172 29.8807104094721 28.0875802114959 1.06384067920676 0.289077007891125 65.2000436416076 57.0141710508086 1.14357610467587 0.254585585404311 PLXNC1 other 1 1 1 1.06384067920676 1.14357610467587 8.14061871337906e-21 253.230764521001 37.4693968105478 6.75833576402051 2.66691208080315e-10 -274.485047008721 75.974620933352 -3.61285181336423 0.000408687920921422 APPL2 other 1.15564223255129e-16 1 3.42644864141589e-06 6.75833576402051 -3.61285181336423 2.53328595481319e-14 157.716429740233 38.5979161507925 4.08613846208884 7.01648375220464e-05 -339.37569032522 77.7660519674566 -4.36405966021319 2.32151321633271e-05 PWP1 essential 3.35305728979074e-10 0.335922962403344 0.652532988955032 4.08613846208884 -4.36405966021319 0.15733465573444 0.188676381299427 27.9626776838276 0.00674743611583912 0.994624986661099 -90.597753491196 55.9986360569203 -1.61785643134428 0.107713721201624 DRAM1 other 1 1 1 0.00674743611583912 -1.61785643134428 6.69276457765403e-10 116.715376137802 29.7865808193019 3.91838784202346 0.000133387925852671 -153.906417949032 60.3966004067102 -2.5482629305727 0.0117985886443206 WASHC4 other 7.62038174811687e-06 1 1 3.91838784202346 -2.5482629305727 0.000483474531673997 -19.8624743185139 22.8225612852074 -0.870299966348998 0.385499888832544 -171.129808880322 45.9193183524024 -3.72674976503367 0.000272440897870839 SLC41A2 other 1 1 1 -0.870299966348998 -3.72674976503367 0.00808045780209444 92.2674093281927 40.7593670378088 2.26371055376313 0.0249794920114393 -85.4887372479444 88.4601504918322 -0.966409584119325 0.335344714525455 VILL other 1 1 1 2.26371055376313 -0.966409584119325 1.69883185064304e-09 1461.3987094838 287.497829782545 5.08316431671556 1.09761879878807e-06 -896.331364124597 675.796805955715 -1.32633264351849 0.186758954325524 FLNB other 1.89521681257738e-05 1 0.0119695330007839 5.08316431671556 -1.32633264351849 1.10650982001461e-15 74.4045801526718 10.059653674878 7.39633615205683 9.64387870156566e-12 -12.202749802211 16.9562212896114 -0.719662098871476 0.472867974694953 NEK3 other 1.50086991986782e-11 1 1.28591478606676e-07 7.39633615205683 -0.719662098871476 1.15299642266788e-08 171.741071894061 36.3289082746658 4.72739424470474 5.45062748952343e-06 -84.5968015223396 64.1602966775629 -1.31852260514755 0.18946646981482 VPS36 other 0.000122436690123102 1 0.0566265689886589 4.72739424470474 -1.31852260514755 0.000647982899034531 80.5912087978198 26.222444230037 3.07336753549103 0.00251760882324927 -13.4889876852181 44.6059127126173 -0.302403579815162 0.76276615381667 RNASEH2B other 1 1 1 3.07336753549103 -0.302403579815162 9.74531192970361e-08 410.667498214618 78.5426658972615 5.22859128249855 6.08635890788123e-07 26.8613141066403 138.556434163712 0.193865512408483 0.846562192572763 CKAP2 other 0.000970438161959886 1 0.00674490294171398 5.22859128249855 0.193865512408483 0.000405213349764709 94.3105968898406 26.1383370933632 3.60813300987641 0.00042203658091246 -1.52774932489065 47.7204383563492 -0.0320145702242358 0.974503858502345 TBC1D4 other 1 1 1 3.60813300987641 -0.0320145702242358 0.351932088802568 8.14756790574003 5.64959063083827 1.4421519076562 0.151477071274097 6.1185939210677 9.97771274162237 0.61322610497131 0.540714766206386 THSD1 other 1 1 1 1.4421519076562 0.61322610497131 1.5729304641046e-12 136.525031267065 17.2671407660634 7.90663799622162 6.13110283870527e-13 64.8417005760186 32.5384614304862 1.99277094630131 0.0481634248824735 BORA essential 1.98519553874641e-08 1 8.35362761773593e-09 7.90663799622162 1.99277094630131 5.81625953067028e-05 50.8175367757933 27.4316797310099 1.85251276167194 0.0658788743547572 -111.493658479375 46.2572529432358 -2.41029571332724 0.0171261601849577 LRCH1 other 0.439476570137446 1 1 1.85251276167194 -2.41029571332724 2.94570440857303e-15 261.22926124988 41.4005426697509 6.30980282876209 2.86497982266535e-09 -132.697746358135 70.6148763888967 -1.87917551009124 0.0621223810932976 SUCLA2 other 3.96668555658444e-11 1 3.5601945155096e-05 6.30980282876209 -1.87917551009124 5.00802252815502e-07 156.466801430571 34.7825045728617 4.4984340073271 1.37489634035015e-05 -19.8767428601046 59.0601730866648 -0.336550704498233 0.736932347923562 RCBTB1 other 0.00468600667959465 1 0.137599625742243 4.4984340073271 -0.336550704498233 2.03894045429701e-16 253.686751615381 37.6022240467052 6.74658901293392 2.93222592331504e-10 -120.025710541774 63.6791696778068 -1.88485043302323 0.0613463837825555 MED4 essential 2.79375621047776e-12 1 3.76263230479786e-06 6.74658901293392 -1.88485043302323 0.0151482480499521 35.3439589488417 36.5592176450708 0.966759171160957 0.33524155697228 -109.18059277824 62.0770053377813 -1.75879284421265 0.0806794392698308 PHF11 other 1 1 1 0.966759171160957 -1.75879284421265 4.2961484709316e-20 183.803474236082 24.0965036381535 7.62780679704313 2.42520778661665e-12 -93.0439193725804 40.8985314865334 -2.27499413770435 0.0243045573702227 COG3 essential 6.07303547850892e-16 1 3.27427303271114e-08 7.62780679704313 -2.27499413770435 1.125531234286e-06 480.291554801941 101.33200266193 4.73978153184555 5.03061465420126e-06 -60.0295793886299 185.316752585332 -0.323929588400208 0.746454918133807 LMO7 other 0.0102232002010197 1 0.0524089434674687 4.73978153184555 -0.323929588400208 0.46118673282862 39.9492385786802 32.9572175625495 1.21215446974128 0.227438352546356 49.4167098311405 60.8392983125261 0.812249831963728 0.417989024609236 SCEL other 1 1 1 1.21215446974128 0.812249831963728 3.97490847238986e-07 3190.07211676438 983.360045063767 3.24405301270656 0.00145093608682138 -3462.29720564377 1673.50716572598 -2.06888699167405 0.040261499138257 ITM2B other 0.00375549352471394 1 1 3.24405301270656 -2.06888699167405 0.0105716492080432 416.815644693407 152.403659560549 2.73494511808498 0.00702907829264875 -16.9395818745623 277.737979379978 -0.0609912332205277 0.95145135025267 SPRY2 other 1 1 1 2.73494511808498 -0.0609912332205277 4.34233930753888e-15 311.342765803624 45.0025293074884 6.91833927102885 1.1715785391044e-10 -77.094189146446 76.2115479164889 -1.01158146309958 0.313335292735291 NUDT15 other 5.83176169002472e-11 1 1.5228177851279e-06 6.91833927102885 -1.01158146309958 0.213259231555087 59.5364559298569 33.6852267932797 1.76743521114528 0.0792735060660821 50.2754019004926 62.1832094202708 0.808504455932819 0.420133961688482 EDNRB other 1 1 1 1.76743521114528 0.808504455932819 5.77484645176749e-08 108.854765977298 24.921049473981 4.36798482708156 2.34539089676448e-05 -46.8393047158217 42.3155696666832 -1.10690474179532 0.270130969939476 RCBTB2 other 0.000585222939422118 1 0.229519953157372 4.36798482708156 -1.10690474179532 0.772157523552006 173.573298078854 253.94838873504 0.683498323984067 0.495325795821066 247.608608340585 431.210544335387 0.57421742485963 0.566663924830565 LCP1 other 1 1 1 0.683498323984067 0.57421742485963 0.00116571117647342 35.770175711398 16.7876544661923 2.1307429089295 0.0347630131006925 -39.3109356944457 28.5051864627949 -1.3790801104127 0.169950585766571 SETDB2 other 1 1 1 2.1307429089295 -1.3790801104127 3.73667587615766e-05 535.635925110412 150.540410388072 3.5580873184125 0.000498663669860805 -190.628504881061 327.829073732322 -0.581487488924525 0.561773279283191 SCRN1 other 0.289069245779557 1 1 3.5580873184125 -0.581487488924525 0.000161592310831434 34.2158341187559 16.2261606036483 2.10868331421931 0.0366008144777104 -80.4521789865803 37.0990971296008 -2.16857511937639 0.0316599048092701 C7orf25 other 1 1 1 2.10868331421931 -2.16857511937639 0.375987326333124 -247.495039450042 392.571149990107 -0.63044632662456 0.529343126719027 -1328.9905446089 947.339566270521 -1.4028660808931 0.162682768489198 TNS3 other 1 1 1 -0.63044632662456 -1.4028660808931 0.000191513369106815 9.17102748787298 2.8959564881632 3.16683884076236 0.00186492563916239 -5.94465676907248 6.66707926070471 -0.891643332352423 0.374002753660546 SPDYE1 other 1 1 1 3.16683884076236 -0.891643332352423 2.6487686855196e-05 515.849516546371 110.341121065527 4.67504328001191 6.40424132458993e-06 490.733589813428 260.001958015423 1.88742267004127 0.0609973311287283 IGF2BP3 other 0.209332189216614 1 0.0661173874350665 4.67504328001191 1.88742267004127 0.0292641926323147 -531.132628202218 342.313626483706 -1.55159651007203 0.1228248621053 774.192361962261 806.60965088681 0.959810437565545 0.338664956247494 GPNMB other 1 1 1 -1.55159651007203 0.959810437565545 7.94727344772352e-05 128.319892046357 37.812465583734 3.39358701066975 0.000875884424123616 -48.5606180875271 89.8160917306036 -0.54066723625852 0.589513068246972 RAPGEF5 other 0.590959253572721 1 1 3.39358701066975 -0.54066723625852 2.7568455856432e-16 549.552998323021 261.800750760975 2.09912689984898 0.0374806349349162 -2774.09810327878 508.051984531237 -5.46026427952712 1.92755310826931e-07 RAC1 essential 3.7713647611599e-12 0.00281673335711394 1 2.09912689984898 -5.46026427952712 6.51804467431503e-10 257.804284970797 308.332262416316 0.836124909376836 0.404414595543174 -2717.3292083502 598.351293341539 -4.54136096735926 1.14047322885573e-05 KDELR2 other 7.42731190638197e-06 0.165528284436121 1 0.836124909376836 -4.54136096735926 1.55133374457705e-13 156.800944209905 28.1924693226964 5.56180242372995 1.16253592972861e-07 -147.765485269417 66.4312375513913 -2.2243373857834 0.0275898119706974 NUPL2 other 2.0144068673333e-09 1 0.00134644911381168 5.56180242372995 -2.2243373857834 0.148123713009123 -11.1309572948087 9.67294817202315 -1.15073058356732 0.251615233099741 15.7083752271085 22.9761901772821 0.683680588727033 0.49519766549013 IL6 other 1 1 1 -1.15073058356732 0.683680588727033 1.33596817287243e-13 134.860273438302 52.2372518963699 2.58168775236956 0.0108027275202156 -424.110776384128 100.696262438206 -4.21178270290213 4.38266221363055e-05 ZDHHC4 other 1.7372930120033e-09 0.631103358762799 1 2.58168775236956 -4.21178270290213 0.500995010540396 4.10152125826107 14.9318636821608 0.274682474041146 0.783928343702816 41.1102335491051 36.4453025978602 1.12799814019157 0.261075001910857 AOAH other 1 1 1 0.274682474041146 1.12799814019157 4.99764930708804e-13 346.180849445939 91.0778663169065 3.80093280008776 0.000207666560494771 -739.106232588362 203.533300892581 -3.63137741758751 0.000384035005390055 BZW2 other 6.40498735196403e-09 1 1 3.80093280008776 -3.63137741758751 2.30047230071235e-10 399.093599198198 68.0928577367358 5.86101997277299 2.75805022429908e-08 -161.353361874831 161.709183642491 -0.997799619294063 0.319962329287798 TBRG4 other 2.67982018309982e-06 1 0.00032931119678131 5.86101997277299 -0.997799619294063 0.000471925881188485 227.360889780834 82.7477575485274 2.74763808127971 0.00675437675640314 -231.176505653029 192.623729725221 -1.20014551676891 0.232013396218779 DDX56 essential 1 1 1 2.74763808127971 -1.20014551676891 0.000474682941437964 13.7723524738215 16.8939310806349 0.815224852527573 0.416202615288519 -125.891486316391 40.8064848644008 -3.08508529305393 0.00241297932463059 HUS1 essential 1 1 1 0.815224852527573 -3.08508529305393 0.0289243547708697 111.637611670667 43.0047379980729 2.59593749125201 0.0103583521145473 56.4211561780788 102.129082338041 0.552449457945079 0.581451910841033 NACAD other 1 1 1 2.59593749125201 0.552449457945079 8.37788239572321e-07 163.11888143234 33.6040730947431 4.85414018034194 3.02138154747497e-06 -3.92364437386343 80.3977271399687 -0.0488029265682169 0.96114170619767 CCM2 other 0.00769173382751348 1 0.0320054947324023 4.85414018034194 -0.0488029265682169 0.193746122708215 21.555031889552 14.0771524729217 1.53120682119587 0.12783867912846 53.8051279424196 33.679579860298 1.59755935690415 0.112259665203528 MYO1G other 1 1 1 1.53120682119587 1.59755935690415 0.0250784101765107 946.683340915076 384.79894354299 2.46020254681211 0.0150446022386353 544.953384250723 759.207189496204 0.717792707695964 0.474024274756477 TTYH3 other 1 1 1 2.46020254681211 0.717792707695964 6.05207172601689e-05 97.5584377732442 28.1265021188126 3.46855920302978 0.000689156265849787 -64.6729559209283 58.2967040873978 -1.10937585466189 0.269104590473633 CIDEB other 0.455963083838112 1 1 3.46855920302978 -1.10937585466189 7.88525103001923e-19 186.776027886271 19.1135370624266 9.77192380856789 7.94100260606445e-18 -49.0749443534503 54.908678450153 -0.893755700166802 0.372856329709125 TTC5 other 1.1061430144911e-14 1 1.12722531993085e-13 9.77192380856789 -0.893755700166802 0.258626420142922 -0.984202846934215 4.79135346151392 -0.205412281694458 0.83752852555604 -11.3130172370875 7.25675006586412 -1.5589647065708 0.12111210121572 NKX2-8 other 1 1 1 -0.205412281694458 -1.5589647065708 0.634417687858175 -6.17203386909619 9.36176558337847 -0.659280967262677 0.510726230203549 -12.9436702243771 14.1788731638096 -0.912884266248652 0.362768325351971 NKX2-1 other 1 1 1 -0.659280967262677 -0.912884266248652 1.64337547042789e-05 118.154723613091 24.5168297724106 4.81933123939432 3.65744806480559e-06 41.3606459528469 55.3187371104178 0.747678781427888 0.455890327100864 ZFHX2 other 0.132653267972939 1 0.0385275579146621 4.81933123939432 0.747678781427888 2.93424132081547e-06 93.407601600941 25.7645276509326 3.62543427407101 0.000391513514778326 -98.5421825015423 45.7109432558351 -2.15576786394499 0.0326547789034981 MTHFS other 0.0255543076629819 1 1 3.62543427407101 -2.15576786394499 0.0475517277076144 94.5904494859376 46.9511618791347 2.01465620232018 0.0457040621360669 178.681791146232 83.8216020969715 2.13169143366549 0.0346398557115205 ADAMTS7 other 1 1 1 2.01465620232018 2.13169143366549 3.92588995550588e-08 229.717466406565 49.0274384921651 4.68548783031517 6.12521632122327e-06 -171.215237742346 86.9184590862939 -1.96983747229528 0.0506624887181417 ABHD17C other 0.000402403720439353 1 0.0633592376267336 4.68548783031517 -1.96983747229528 2.43524924786304e-12 404.301855972061 53.9684701925141 7.49144555200198 5.19456114781145e-12 33.7786746275379 96.9631845673535 0.348365978059169 0.728047372975638 IREB2 other 3.05623780606811e-08 1 6.96902323590384e-08 7.49144555200198 0.348365978059169 0.893379731411204 24.061797752809 54.1376519065202 0.444455880619955 0.657336991077573 1.55033707865165 95.0057814522085 0.01631834457813 0.987001544761377 ALPK3 other 1 1 1 0.444455880619955 0.01631834457813 0.670730484051476 4.75475692257686 6.08859153459903 0.780928872557384 0.436066909619072 7.09372041525303 10.2343247837279 0.693130281201526 0.489292523284078 TM6SF1 other 1 1 1 0.780928872557384 0.693130281201526 0.000285112120654919 159.507471488916 38.4473971965481 4.14871963044711 5.52761408243247e-05 103.966317481146 68.6923072604217 1.51350743085388 0.132213791939397 CIB2 other 1 1 0.520093209016071 4.14871963044711 1.51350743085388 6.96897185556346e-07 264.004135818228 47.8985128615925 5.51173971895734 1.42797367313712e-07 -134.953484809806 197.294683212774 -0.684019876320054 0.494970993242369 CALCOCO2 other 0.00644002689172619 1 0.00164559686092322 5.51173971895734 -0.684019876320054 1.23860765913837e-16 198.491685174152 20.741333622816 9.56986126272063 2.23503029832252e-17 -46.0717593846491 83.184653709558 -0.553849265821436 0.580469964414389 RSAD1 other 1.70159920212429e-12 1 3.16547341151419e-13 9.56986126272063 -0.553849265821436 6.48571166451681e-15 806.16849112426 90.8688074438606 8.87178465088051 1.5235017850601e-15 -260.486573268358 365.326495849715 -0.713024038025194 0.476889331924396 NMT1 essential 8.68307077645510e-11 1 2.13351189979816e-11 8.87178465088051 -0.713024038025194 0.385821281259156 8.57759601321708 6.3900957193584 1.34232668647385 0.181427893336283 -5.87959075889707 25.6279518594229 -0.229421016207163 0.818840309836488 MYCBPAP other 1 1 1 1.34232668647385 -0.229421016207163 0.00827041479453346 327.250816653799 118.180464905966 2.76907707982183 0.00629899284825502 704.73527795926 451.330312716901 1.5614623217238 0.120428183456338 SRSF1 essential 1 1 1 2.76907707982183 1.5614623217238 3.56925231031496e-10 631.795034744907 89.8852332647778 7.02890799519659 5.99761029903296e-11 354.999510007722 343.27103443283 1.0341668081441 0.302648527552984 VEZF1 other 4.12212949318275e-06 1 7.86526614615182e-07 7.02890799519659 1.0341668081441 0.00163332708891491 14.1011321163535 3.91428939439417 3.60247562087471 0.000422513872595325 14.3878649585614 15.698547340924 0.916509320646132 0.360805482532407 CHAD other 1 1 1 3.60247562087471 0.916509320646132 6.96936054000174e-11 153.011855587146 21.4140835565512 7.14538425999255 3.29438810869234e-11 -147.202108255995 86.6498957697566 -1.69881460269884 0.0913604166888929 TACO1 other 8.30817469973608e-07 1 4.34694510941954e-07 7.14538425999255 -1.69881460269884 1.26388125113466e-10 447.28251320545 61.6826758617638 7.25134743194099 1.91726144070643e-11 226.223109535726 246.906467726515 0.916229986272782 0.3609881638778 TEX2 other 1.48986321883754e-06 1 2.54248039652079e-07 7.25134743194099 0.916229986272782 6.90030928053578e-15 1210.5624399872 138.238278260561 8.75707116161737 3.24841068435871e-15 1292.19936919876 560.916470969467 2.30372869415898 0.022566483197534 DCAF7 other 9.23399387921299e-11 1 4.53835456711755e-11 8.75707116161737 2.30372869415898 0.00294196454687426 208.329354648356 70.567839178395 2.95218554335638 0.00364641414638546 547.219033313665 285.545533310212 1.91639850559026 0.0571547227287117 LIMD2 other 1 1 1 2.95218554335638 1.91639850559026 4.86640463831104e-05 54.4230936079518 13.1030317275305 4.15347338994872 5.37643864254778e-05 107.004488956789 54.5487973817235 1.96162874513969 0.0515856557695796 BRIP1 other 0.371014689624834 1 0.506836870832979 4.15347338994872 1.96162874513969 6.70577955270521e-14 407.914676806084 47.7809883434572 8.53717536928976 1.11383201761062e-14 355.957091254752 198.141635021466 1.79647801541654 0.0743411208365684 KAT7 other 8.79261814950706e-10 1 1.54822650447877e-10 8.53717536928976 1.79647801541654 0.850644943174431 11.6100507869759 35.0441052579232 0.331298251204488 0.740875520227343 -56.8617572589841 141.511922130153 -0.401816019477755 0.688383843871345 RTP4 other 1 1 1 0.331298251204488 -0.401816019477755 4.54148848058163e-08 311.798217683088 52.3247180808697 5.95890869782026 1.88687866262233e-08 435.926690543488 249.538885122573 1.74692890179966 0.0827966333730805 ACTL6A essential 0.000463374982415675 1 0.000226991503113467 5.95890869782026 1.74692890179966 0.228687871580151 181.907665696758 113.422129497039 1.60381105965311 0.110946801246547 363.166037569902 543.179133562781 0.668593499142446 0.504825179772425 NDUFB5 other 1 1 1 1.60381105965311 0.668593499142446 0.000142623226781839 166.041043983026 38.6905190379966 4.29151761494755 3.23995345405072e-05 135.744313087411 185.289085131326 0.732608253698272 0.46498820556317 MRPL47 other 1 1 0.312849905523137 4.29151761494755 0.732608253698272 0.00358182637936341 259.693415252949 76.6378513455064 3.38857902059614 0.000896264176691917 -35.5355309770725 323.074148633444 -0.10999187377691 0.91256186695092 TRA2B essential 1 1 1 3.38857902059614 -0.10999187377691 0.0123783728572014 24.8397646201114 8.90825876932565 2.78839729102209 0.00595215444964138 51.0624208023053 27.0911193532507 1.88483983022201 0.0612994442064545 SCN2A other 1 1 1 2.78839729102209 1.88483983022201 5.25000410707359e-09 379.524156965768 71.9778988390321 5.27278738456256 4.38476820562673e-07 -533.228670874969 226.860373457106 -2.35047074440169 0.0199928958157621 MARCH7 other 5.69257945329989e-05 1 0.00490480171481406 5.27278738456256 -2.35047074440169 0.87877136377163 -4.28736795943057 8.62781366073349 -0.496924032903381 0.619951277013614 -0.666850127883281 27.4161985098288 -0.0243232163512463 0.98062628321858 GALNT5 other 1 1 1 -0.496924032903381 -0.0243232163512463 0.286462073423167 10.483903235147 6.86884045362386 1.5262988427131 0.12896036539737 0.613923328682865 20.8700632042681 0.0294164575676662 0.976570046778191 SCN7A other 1 1 1 1.5262988427131 0.0294164575676662 0.0158191048247155 48.1352786594728 69.5577214605482 0.692019198569842 0.489960615139433 -525.365498176255 207.14484241612 -2.53622292521714 0.0121949187369003 TANK other 1 1 1 0.692019198569842 -2.53622292521714 0.0744519389613806 0.195806451612853 4.05382743370168 0.0483016247768732 0.961539267509575 -12.2036212278876 7.78338851250951 -1.56790595873171 0.118982537068313 BLK other 1 1 1 0.0483016247768732 -1.56790595873171 0.165056876771671 -69.2343548387098 36.2701094839883 -1.90885431071758 0.0581654954042573 -92.9892195629551 69.6389666610341 -1.33530441391495 0.183772999801757 GATA4 other 1 1 1 -1.90885431071758 -1.33530441391495 9.05838165728658e-08 312.553388161875 52.7054864636386 5.93018695269049 2.0727711912972e-08 360.104147340399 311.83899450569 1.1547758737204 0.25005596044172 SKIL other 0.000904660576113211 1 0.000248877636939055 5.93018695269049 1.1547758737204 1.73492659824638e-16 662.97209540908 78.5488061748842 8.44025679948606 2.10407349485964e-14 -249.997281354195 237.999676972225 -1.05041017086494 0.295164527319981 EPRS essential 2.3794518294949e-12 1 2.91687708592392e-10 8.44025679948606 -1.05041017086494 0.680519022061049 -9.30174235563034 10.5963870026087 -0.877822068346541 0.381398924618676 -11.6995083451934 33.1946648770783 -0.352451467382404 0.724978489527255 HLX other 1 1 1 -0.877822068346541 -0.352451467382404 0.0161368932626732 -9.35176876583668 4.3410001694984 -2.15428896583464 0.0327624953364357 -38.2449549951971 15.3383360222764 -2.49342268546292 0.0137019909421614 IL10 other 1 1 1 -2.15428896583464 -2.49342268546292 1.53549009933183e-11 207.641348888741 34.1093586099987 6.08751842164142 8.55621879612993e-09 -193.531238387813 103.430185296276 -1.87112918567671 0.0631999242821696 KCTD3 other 1.87544760732389e-07 1 0.000104445762844358 6.08751842164142 -1.87112918567671 2.31227081824241e-11 140.820179197223 22.2600975220329 6.32612588771636 2.56709026056698e-09 -95.6993450585837 65.3079451590418 -1.46535532277935 0.144849554164758 RPS6KC1 other 2.80594063793716e-07 1 3.19577066537983e-05 6.32612588771636 -1.46535532277935 1.54689484982871e-14 135.838208146266 16.2769762400753 8.3454203128847 3.9051613041591e-14 -52.8754565906585 66.8829318944061 -0.790567265713434 0.430420241758245 CBWD2 other 2.05613263439233e-10 1 5.39146569652206e-10 8.3454203128847 -0.790567265713434 0.138613284183109 -29.1175431778539 24.8685666863944 -1.17085731337239 0.243464686557519 -161.812526322449 85.1383951541988 -1.90058229344565 0.0592252299200094 IL1RN other 1 1 1 -1.17085731337239 -1.90058229344565 2.85598419328551e-06 625.939276988988 150.034318257804 4.17197401406149 5.0766935657985e-05 -432.462721483453 365.426938939171 -1.1834451032507 0.23849257348741 SMPD4 other 0.0249127501180295 1 0.480153677453222 4.17197401406149 -1.1834451032507 1.15257570437159e-11 324.478459961647 56.8468002803657 5.70794588897413 5.870858049093e-08 -318.383698119862 136.628907541779 -2.33028064007981 0.0211151393099958 WDR33 essential 1.41467141954569e-07 1 0.000690765158056282 5.70794588897413 -2.33028064007981 1.32159961007526e-06 151.253326963762 36.3805986566427 4.15752715867265 5.35632905549732e-05 -127.182210371353 87.3942119995116 -1.45527040591731 0.147656567371243 CCDC115 essential 0.0119261148813191 1 0.505048266642842 4.15752715867265 -1.45527040591731 7.42422484895659e-13 402.635458981324 54.4748070882822 7.39122321863041 8.6691684741956e-12 -19.0470639136599 131.005690844728 -0.145391118438015 0.884592198029717 SAP130 essential 9.46068972502538e-09 1 1.15681384119666e-07 7.39122321863041 -0.145391118438015 0.0558957953585608 182.037812033049 94.1397265876555 1.93369811695331 0.0549842402234419 -121.526358002989 229.621843446396 -0.529245633512034 0.597397120401346 BIN1 other 1 1 1 1.93369811695331 -0.529245633512034 5.67596143210698e-05 149.08732000273 54.841565956514 2.71850953564942 0.00732028296582457 -289.718585175147 131.741522090474 -2.19914405555585 0.0293784918002678 IMP4 essential 0.429219041692973 1 1 2.71850953564942 -2.19914405555585 4.90091750333564e-06 941.060284114127 216.807197726215 4.34053986206907 2.56338066795097e-05 -364.052175724506 521.396554414637 -0.698225127577264 0.486089390005698 HS6ST1 other 0.0416921052008763 1 0.250134685578655 4.34053986206907 -0.698225127577264 1.04498260809494e-09 538.896441763015 89.4916815262347 6.02174897792077 1.21728088695957e-08 -111.598479810483 215.21727546829 -0.518538670130715 0.604826753426287 UGGT1 other 1.17863588367028e-05 1 0.000147680517205935 6.02174897792077 -0.518538670130715 0.0107582371956405 -101.863369629265 34.1217964729393 -2.98528741621353 0.00329645819674348 -55.3225441053418 86.705423198449 -0.638051716542817 0.524387643096263 GYPC other 1 1 1 -2.98528741621353 -0.638051716542817 6.78188834604041e-12 105.949670034035 15.5467113007738 6.81492490497085 1.93931809624626e-10 -64.8825980193015 61.2471465294141 -1.05935707532336 0.291074682310487 STAM other 8.38444856220976e-08 1 2.50559898035016e-06 6.81492490497085 -1.05935707532336 2.54374440654963e-07 203.007855459545 44.7971380342571 4.53171484536136 1.16250490582158e-05 -312.790084664398 181.397022869388 -1.72433968163643 0.0866401329431373 ABI1 other 0.00244402962581289 1 0.117308370046456 4.53171484536136 -1.72433968163643 8.93815543405819e-13 524.099440378821 77.0563412151792 6.80150954631076 2.15325265231327e-10 -515.364782130387 322.664520397025 -1.59721552743466 0.11226758399488 YME1L1 other 1.13657584499484e-08 1 2.77640396989274e-06 6.80150954631076 -1.59721552743466 0.166786395806988 16.3203116545829 20.0358197406696 0.814556722201649 0.41660045032575 -100.801266096743 77.7534380884209 -1.29642197920704 0.196794940750561 DNAJC1 other 1 1 1 0.814556722201649 -1.29642197920704 1.06369421983246e-05 179.772564153969 57.7736274029072 3.11167174773802 0.00220822360755331 -152.535465116279 87.7253488925439 -1.73878436554435 0.0840205427379553 NIPSNAP3A other 0.0876590406563933 1 1 3.11167174773802 -1.73878436554435 2.68350882174124e-05 264.727225771019 131.170428782195 2.01819288256342 0.0452959891375363 -422.077729540297 178.656950391807 -2.36250382990783 0.0193935628092466 LRRC8A other 0.211997196917558 1 1 2.01819288256342 -2.36250382990783 0.000142274850594398 133.11296990715 317.858030007351 0.418781208403235 0.675944768231574 -1854.36932288953 506.615034323105 -3.66031246065798 0.000342991923203598 TXN essential 1 1 1 0.418781208403235 -3.66031246065798 1.11380020167199e-08 518.865896488609 96.8515078513206 5.35733421192714 3.04667931787816e-07 19.8951986005761 132.545678863994 0.150100695632565 0.880882864350354 ODF2 other 0.000118408099439749 1 0.00343939628195266 5.35733421192714 0.150100695632565 4.05788390945233e-09 525.209882280049 118.829860548144 4.41984767008341 1.8343409398948e-05 -418.88952254891 183.997684078003 -2.27660214664076 0.0241610369717676 KIAA0368 other 4.42836871038533e-05 1 0.181544722821389 4.41984767008341 -2.27660214664076 0.000922862214807792 65.6826858129235 33.8432909918576 1.94078896844654 0.0540752047359755 -71.724839266505 46.6566664949145 -1.53729026642576 0.126235163569029 TOR1B other 1 1 1 1.94078896844654 -1.53729026642576 1.35533929775943e-10 270.539576714282 57.7240877388361 4.68677093587511 5.98077173175104e-06 -139.820191129012 79.5789484835273 -1.75699973163072 0.0808672215366862 C9orf78 essential 1.59536988739262e-06 1 0.0619249105105503 4.68677093587511 -1.75699973163072 1.40081407078584e-10 333.610762597056 56.9557522862895 5.85736732824023 2.6710706508984e-08 -57.0975463037854 86.4412582152776 -0.660535807583768 0.509878049912664 SMC2 essential 1.64735734724415e-06 1 0.000319166232075849 5.85736732824023 -0.660535807583768 0.0893192256883229 -9.05902036166886 49.5711285001257 -0.18274791467872 0.855231589649289 -162.775771383204 79.7133739003199 -2.04201332121197 0.0428236754345585 KLF4 other 1 1 1 -0.18274791467872 -2.04201332121197 2.8538306450899e-05 122.217596877893 56.9364208422752 2.14656269343763 0.0333639492985904 -169.970304955845 78.4930637889576 -2.16541814972136 0.031865432280634 TOR1A other 0.224539395155673 1 1 2.14656269343763 -2.16541814972136 2.99036496798334e-07 185.280680966172 46.4611199987958 3.98786514339246 0.000102201494757355 -81.4159950603489 65.7479978351018 -1.2383037923762 0.217463661426043 RALGPS1 other 0.00285101396047532 1 0.934326065071744 3.98786514339246 -1.2383037923762 4.18580672337186e-05 870.69611231871 485.696582212571 1.79267498311865 0.0749626154453115 -1766.42431315255 676.77089363143 -2.61007725032948 0.00993404808262862 FAM129B other 0.321386240220491 1 1 1.79267498311865 -2.61007725032948 0.00265305358418569 -21.8144987669778 106.052690163508 -0.205694911966355 0.837302667484634 -441.761811563002 145.602296148082 -3.03403052870621 0.00283609313542326 ST6GALNAC4 other 1 1 1 -0.205694911966355 -3.03403052870621 0.00243161220704557 -162.291778975738 301.289616547963 -0.538657059726125 0.590886432905409 -1465.06953335579 450.624846801385 -3.2511956314773 0.00140646492182296 TMOD1 other 1 1 1 -0.538657059726125 -3.2511956314773 1.64436918570017e-08 777.26523061766 149.261539463214 5.20740462287152 5.96624162112245e-07 -120.727781285947 220.694389792304 -0.54703602297985 0.585135665799344 DAB2IP other 0.000173102744178657 1 0.00661536870950057 5.20740462287152 -0.54703602297985 6.66808972849917e-10 471.620104764279 86.9115564939614 5.42643721720767 2.15512919979364e-07 -85.335495135944 121.102791144562 -0.704653413265081 0.482076615255295 STXBP1 other 7.59295377384201e-06 1 0.00245620074900481 5.42643721720767 -0.704653413265081 2.42580328743348e-06 148.811287430758 36.795746354743 4.0442524523375 8.22972046262706e-05 -36.3993417003398 50.9710964358756 -0.714117298734826 0.476221778331291 SLC2A8 other 0.0213300883064026 1 0.759685495905104 4.0442524523375 -0.714117298734826 0.746975440417069 -57.24572705488 93.7245503593294 -0.610786894526635 0.542229551165 5.75075638405787 132.631360033525 0.0433589490645672 0.965470849375306 ANGPTL2 other 1 1 1 -0.610786894526635 0.0433589490645672 1.54262725753592e-08 412.906085787609 76.0820856819795 5.42711312507312 2.1646894239018e-07 -37.4314868804662 125.628333487364 -0.297954178340121 0.766137144133859 CDK5RAP2 other 0.000162623765489437 1 0.00246601419170893 5.42711312507312 -0.297954178340121 0.000466274236691926 18.9207886742707 6.12250520490468 3.09036710317754 0.00236306372486533 -7.16674499914025 9.61172902120992 -0.745624952942973 0.457001821432143 ZFP37 other 1 1 1 3.09036710317754 -0.745624952942973 0.00675964465811566 12.1639135668023 14.8586139418034 0.818643893329796 0.414222614897006 -54.1546328881756 23.3265576850759 -2.32158699192994 0.021532418493477 SLC31A2 other 1 1 1 0.818643893329796 -2.32158699192994 5.16150662927968e-10 366.271645555111 65.8411129017549 5.56296255352859 1.10920471396638e-07 -107.260643090502 103.364050251781 -1.03769775690126 0.300996265569606 SLC31A1 other 5.9130219945028e-06 1 0.00128556826348703 5.56296255352859 -1.03769775690126 0.494359927673144 23.6842925999433 19.9100017888456 1.18956757769918 0.236023759963857 19.7050373310652 33.0523555782372 0.596176489885026 0.551921404065463 TLR4 other 1 1 1 1.18956757769918 0.596176489885026 9.56027012273776e-09 68.1932584799734 22.7536513675528 2.99702484574491 0.00316995338877584 -112.679325690743 34.1431962722573 -3.30019851663094 0.00119578046986189 ZNF189 other 0.000102046323290103 1 1 2.99702484574491 -3.30019851663094 1.50961730865528e-11 105.44708866093 18.5361172684793 5.68873659643074 6.20814760358464e-08 -39.3416819269559 27.7656936682316 -1.41691694783657 0.158514005046355 STX17 other 1.84445042771502e-07 1 0.000729643587849302 5.68873659643074 -1.41691694783657 2.52318649725544e-12 414.442872700178 68.9791749358034 6.00823180453936 1.24771724812912e-08 -181.564800825357 108.290497990667 -1.6766457278736 0.0955892374987158 PRPF4 essential 3.16508514215722e-08 1 0.000151248284818212 6.00823180453936 -1.6766457278736 2.92200676813218e-07 374.448624104591 172.353994960936 2.17255552555924 0.0313530371506109 -768.184874936394 236.628956586735 -3.24636885534683 0.0014361982916222 FPGS other 0.00278905546018217 1 1 2.17255552555924 -3.24636885534683 6.52336027789032e-14 366.093250444049 51.0386802927787 7.17285886594224 2.72661203749404e-11 23.2477797513318 70.3623854232634 0.330400676604201 0.741537717408624 USP20 other 8.55597792319182e-10 1 3.60485377477087e-07 7.17285886594224 0.330400676604201 0.0630396567834944 29.3164565081317 84.2422070432188 0.348001999675667 0.728301886004815 -253.956606557123 134.38124437602 -1.88982181059816 0.0606133241571901 KIF12 other 1 1 1 0.348001999675667 -1.88982181059816 1.81952470694217e-08 680.616117191617 171.939916005832 3.95845323763291 0.000113762629796097 -688.495418021891 281.443335763829 -2.44630208121053 0.0155298270247846 ATP6V1G1 essential 0.000191086484723067 1 1 3.95845323763291 -2.44630208121053 4.31962892341646e-10 289.358903116695 58.7727038257711 4.92335530409637 2.15748161815898e-06 -151.137811065475 88.5566873613119 -1.70667868874579 0.0898843820730722 TEX10 essential 4.96800522482127e-06 1 0.0230893682775374 4.92335530409637 -1.70667868874579 2.39733339496504e-09 72.0134335946907 13.3021680468691 5.41366139271111 2.28866643322309e-07 -8.21890991047241 18.4267519344879 -0.446031397160652 0.656193018571744 GARNL3 other 2.65121100149184e-05 1 0.00260335806779127 5.41366139271111 -0.446031397160652 4.69712330280144e-07 73.2142048403079 36.921334060588 1.98297831601001 0.0491142510193091 -192.685946124451 55.4026400027336 -3.47791993513205 0.000653947546349391 MRPL50 essential 0.00440965935667 1 1 1.98297831601001 -3.47791993513205 1.18431044156339e-08 288.161819391709 91.4083041970147 3.15246871630642 0.00194855488623457 -365.65083962892 125.496665455331 -2.91362992237485 0.00410843849486328 DPM2 other 0.000125714553371953 1 1 3.15246871630642 -2.91362992237485 0.0452450708488972 0.0667343895928468 64.2580978035092 0.00103853664944938 0.999172686210629 -198.319351826061 92.6690550518637 -2.14008173186906 0.0338928887166767 WDR38 other 1 1 1 0.00103853664944938 -2.14008173186906 8.61991943202935e-05 91.8790487555407 104.711526184146 0.877449237001492 0.381591991393134 -508.762407304807 156.940941661195 -3.24174432700377 0.00145266626323221 TSTD2 other 0.637528435300209 1 1 0.877449237001492 -3.24174432700377 0.440165859004984 -20.3165034153882 59.8369841699111 -0.339530872038908 0.734666514073255 -110.236644541822 89.4184583675975 -1.23281754745359 0.219498440350156 GABBR2 other 1 1 1 -0.339530872038908 -1.23281754745359 8.25994649778549e-09 484.456148728758 138.540507833725 3.49685558616687 0.000612378645492937 -572.487913318405 198.872284061314 -2.87867118347121 0.00455064346628612 PSMB7 essential 8.84970667772738e-05 1 1 3.49685558616687 -2.87867118347121 0.395511480184683 67.3047358714269 52.1092789560825 1.29160750675808 0.198391340395578 78.2599789224082 74.8018863856188 1.04623001776937 0.297062924214598 NR5A1 other 1 1 1 1.29160750675808 1.04623001776937 2.76239505522539e-12 60.0987043982271 11.0450124163831 5.441252769357 2.00977556801703e-07 -33.8735296624616 16.5541914291113 -2.04622072950621 0.0424135906980099 TRMO other 3.46072852518637e-08 1 0.00229395783333464 5.441252769357 -2.04622072950621 5.72447005369053e-08 133.268970600989 30.1812791940589 4.41561703677631 1.8665308197062e-05 -53.5314803572976 43.7075225520833 -1.22476583506896 0.222497910783667 RABEPK other 0.000580404018743683 1 0.184599898068943 4.41561703677631 -1.22476583506896 1.44698316061017e-08 149.194935526682 30.3102995859501 4.92225209135969 2.14477055174456e-06 -37.9111600827971 43.7116397307282 -0.86730125697267 0.387100618795225 GOLGA1 other 0.000152844831255252 1 0.0229597687564255 4.92225209135969 -0.86730125697267 9.2623479722504e-07 26.7967950903512 10.5716766070035 2.53477249508361 0.012237000285104 -44.4980075860893 15.8447588541781 -2.80837392323933 0.0056160551469029 XPA ts 0.00847504839460912 1 1 2.53477249508361 -2.80837392323933 9.52183649070025e-16 421.792959427208 53.7964669594143 7.84053272021416 6.58073603865079e-13 -10.542996718377 80.6297882413457 -0.130758085173423 0.896135150013507 NCBP1 essential 1.29249408524765e-11 1 8.96164633743464e-09 7.84053272021416 -0.130758085173423 1.00917061031373e-07 558.377770201161 188.303093528476 2.96531384449464 0.00349923993928629 -799.433653682236 282.227428947068 -2.83258667190768 0.00522725320721067 ANP32B other 0.00100402384020113 1 1 2.96531384449464 -2.83258667190768 8.6176072894928e-13 140.758215074904 25.0833125063915 5.61162785174556 8.92782348382565e-08 -115.672606894697 39.6329276843268 -2.91859859094995 0.00403640437309921 PDCL other 1.09615964722348e-08 1 0.00104000215763085 5.61162785174556 -2.91859859094995 0.0451396046185513 156.141792145248 1845.00542832757 0.0846294486443788 0.932663805526854 -5576.68377216696 2660.75273705562 -2.09590455155863 0.0376948270722539 RPL35 essential 1 1 1 0.0846294486443788 -2.09590455155863 0.253216119738152 57.977756286267 127.103749568111 0.456145129339387 0.64891596588752 -216.877448017408 194.560053912087 -1.1147069691675 0.266679474535456 CTSV other 1 1 1 0.456145129339387 -1.1147069691675 0.199710128561453 9.98458123226649 28.4652971109353 0.350763288833925 0.726239156982852 67.1383337498714 40.2817730798098 1.66671744108312 0.0975771028411217 LMX1B other 1 1 1 0.350763288833925 1.66671744108312 2.51922166658547e-08 242.929177657988 72.6213394332355 3.34514867880294 0.00102876932678288 -288.637515770158 104.730004963064 -2.75601548832117 0.00654377544092291 ARPC5L other 0.000261747131158231 1 1 3.34514867880294 -2.75601548832117 0.27089251156239 15.8102538576406 30.6898952665905 0.515161544876692 0.607193474511683 269.770912710982 166.533364399309 1.61992111120828 0.107335806075519 ENPP2 other 1 1 1 0.515161544876692 1.61992111120828 6.24299346171345e-05 49.1992371127866 11.0763663060346 4.44182105876924 1.72165700008926e-05 13.6961012834969 59.9737334291709 0.228368328939736 0.819670936777646 DSCC1 other 0.469597968190086 1 0.170805590978855 4.44182105876924 0.228368328939736 3.00535433610312e-11 551.242126896581 77.0919203442284 7.15045266008671 3.39851043225934e-11 -190.582078033743 434.192205020798 -0.438934821560451 0.661332062947122 DERL1 other 3.63167017974701e-07 1 4.48365481327975e-07 7.15045266008671 -0.438934821560451 0.0154181102782153 191.362310399892 137.44042554059 1.39232914658997 0.165939764131143 2910.9362994464 1175.72566140195 2.47586354113881 0.0144341760033212 MYC og 1 1 1 1.39232914658997 2.47586354113881 0.186488575574611 57.5909022669268 58.6211717106881 0.982424959895957 0.327462007218531 557.867123418542 317.200046061246 1.75872333672621 0.0806502278044 NOV other 1 1 1 0.982424959895957 1.75872333672621 0.482828064316742 4.7808216538108 15.1168638040093 0.316257506569771 0.752240941990546 -28.6142288624329 35.9395281956354 -0.796177086874164 0.427170826349881 IL33 other 1 1 1 0.316257506569771 -0.796177086874164 4.15131602517895e-19 131.111819375694 16.2411884708561 8.07279711155176 2.00196007780398e-13 -45.5866451156682 38.0549530023446 -1.1979162111397 0.232826563515792 RANBP6 other 5.83550493659405e-15 1 2.74268530659145e-09 8.07279711155176 -1.1979162111397 3.97683428401837e-11 178.227020357804 27.0395988116076 6.59133375460047 6.96671430367878e-10 2.02346631023362 60.0604507127847 0.0336904949300171 0.973168748204258 POLR1E essential 4.78572237738771e-07 1 8.83379373706469e-06 6.59133375460047 0.0336904949300171 1.36605460751285e-17 228.868051761814 29.5148251675873 7.75434211323578 1.32271620784135e-12 -115.844947873987 65.3932989426757 -1.77151099190664 0.0785337993067777 PLAA other 1.89690342799234e-13 1 1.7925450048666e-08 7.75434211323578 -1.77151099190664 0.00177687474728934 163.364641317515 50.7127549374404 3.22137185248647 0.001586651479876 7.46931569061167 125.765920249725 0.0593906177109056 0.952725677543452 IL11RA other 1 1 1 3.22137185248647 0.0593906177109056 1.52460538003036e-20 513.110690423164 53.3029206309602 9.62631473752924 2.23299957550124e-17 -92.0262187577334 137.351167106786 -0.670006820445772 0.503883581695319 UBAP2 other 2.15990844188901e-16 1 3.16282059873996e-13 9.62631473752924 -0.670006820445772 1.16166068362084e-24 108.972053707789 12.100319985148 9.0057166952231 9.85230163245677e-16 -115.054566858985 29.8450650994414 -3.85506168191064 0.000172019616787128 APTX other 1.67116505945694e-20 1 1.38139121188676e-11 9.0057166952231 -3.85506168191064 3.20741557406193e-22 610.327950915897 56.7319251516703 10.758104000247 3.06350260243912e-20 88.4230624404726 132.465736159119 0.667516483917459 0.505496009961028 RNF38 other 4.57762350730119e-18 1 4.38877382825428e-16 10.758104000247 0.667516483917459 0.539345730734635 -5.87510810090583 21.3492941592018 -0.275189805203634 0.783576141313604 43.1106560928044 52.9455287910574 0.814245453340072 0.416887174128158 CCL21 other 1 1 1 -0.275189805203634 0.814245453340072 0.298614907104394 5.95754314937142 5.78748490294915 1.02938379093406 0.305074497451534 -8.06415687945755 15.076622211497 -0.534878221814702 0.593582577634417 SIT1 other 1 1 1 1.02938379093406 -0.534878221814702 0.163507055137076 0.363195889228656 7.04094144673751 0.0515834270141455 0.958932111404362 -29.3887638028189 18.1409001382151 -1.62002786956031 0.107414193809928 DMRT1 other 1 1 1 0.0515834270141455 -1.62002786956031 0.0101505022823057 78.0842328828158 36.2652301617583 2.15314317693633 0.0329964579124995 -80.3643546710233 92.4009256123628 -0.869735385640671 0.38591281616186 DNAJB5 other 1 1 1 2.15314317693633 -0.869735385640671 0.101798670687272 26.0256591064911 18.5872872985876 1.40018598133299 0.163701891628951 -37.667970575734 48.6932697819355 -0.7735765280176 0.440504388646207 SPAG8 other 1 1 1 1.40018598133299 -0.7735765280176 8.40706382881181e-08 182.451748590978 61.8858352259613 2.94819885559917 0.00374233484086453 -487.434763737562 152.889442405858 -3.18815188326493 0.00176408812565695 DCTN3 essential 0.000842051513093791 1 1 2.94819885559917 -3.18815188326493 7.69218361916687e-11 63.9088536117622 13.4740457322542 4.74310796339193 5.12763877369649e-06 -96.1683984908689 35.1004107262749 -2.73980835269488 0.00694836905986009 CD72 other 9.14754475991324e-07 1 0.0533838472729542 4.74310796339193 -2.73980835269488 1.099162523466e-15 203.301531944935 27.1097506349562 7.49920331922164 6.70353496769394e-12 -102.650782444994 70.3976339313239 -1.45815671227153 0.14703705125967 TMEM8B other 1.49101396308163e-11 1 8.97201120076156e-08 7.49920331922164 -1.45815671227153 1.03924549941531e-08 96.4622513723534 79.55480803184 1.21252572608492 0.227217456731657 -913.549926728611 183.198687884974 -4.98666195307145 1.67764737093712e-06 GRHPR other 0.000110648468322748 0.0244634539630051 1 1.21252572608492 -4.98666195307145 0.000292533625268997 155.901059511786 57.9789243676344 2.6889263850989 0.00799647478379038 -199.849278731635 130.220831630865 -1.53469514999063 0.127008224447101 ALDH1B1 other 1 1 1 2.6889263850989 -1.53469514999063 3.28281320154774e-06 86.5868744232948 43.2341389297091 2.00274312306924 0.0471497957264765 -373.971138571007 112.295947132662 -3.33022827733232 0.00111139854806898 HINT2 other 0.0284455763914112 1 1 2.00274312306924 -3.33022827733232 0.00201176571373144 35.7051992329012 66.190598993194 0.539430066746677 0.590447020980916 -494.0264411326 172.429072681392 -2.86509944900906 0.00481180725828707 ARHGEF39 other 1 1 1 0.539430066746677 -2.86509944900906 0.0203056902592457 11.1592487311253 4.92596424844959 2.26539377232337 0.0249699729799986 -5.07270988890912 11.1190906012998 -0.456216256419041 0.648917056091286 IGFBPL1 other 1 1 1 2.26539377232337 -0.456216256419041 8.39860728596026e-22 327.664147697317 32.6776470965808 10.0271646464902 1.50166923022755e-18 15.0115527272392 75.1131252965513 0.199852591247837 0.841857826330429 DENND4C other 1.19738944075935e-17 1 2.13912781845915e-14 10.0271646464902 0.199852591247837 0.000118062645628412 8498.52504972544 3090.33098979277 2.75003715711867 0.0066632691330611 -10640.836883532 7058.05473279353 -1.50761609060524 0.133675265434875 RPS6 essential 0.858669621655439 1 1 2.75003715711867 -1.50761609060524 5.82279533989701e-11 327.928304180793 70.9237225054331 4.62367586748809 8.11295932983452e-06 -670.783063742846 206.842871463124 -3.24295954217805 0.00146004046012575 CNPY3 other 6.95998726977889e-07 1 0.0830280257815265 4.62367586748809 -3.24295954217805 5.77249251487771e-57 4548.86648142124 177.223212981809 25.6674416679723 3.95082906839339e-57 1310.06523529563 1155.02933547013 1.13422680711602 0.258485027763035 FOXP4 other 8.42841632097295e-53 1 5.76860552276118e-53 25.6674416679723 1.13422680711602 4.97786344948175e-08 143.326578790894 47.6855629608178 3.00565978236772 0.00310106597102442 -482.271145230512 138.397210231509 -3.48468834323882 0.000644007316174454 PPIL1 other 0.000506149155543304 1 1 3.00565978236772 -3.48468834323882 1.37906839895402e-25 325.18286033832 28.449132694183 11.4303259728129 4.76967367163313e-22 -76.2577100517266 86.321750893648 -0.8834124570258 0.378455934773284 KLC4 other 1.9884787244518e-21 1 6.86212951137859e-18 11.4303259728129 -0.8834124570258 2.34855087752977e-10 230.075922860181 41.4756777424682 5.54724926470821 1.23554623802599e-07 -214.612947512423 119.008756902728 -1.80333744421713 0.0732901221519121 KIF13A other 2.73488749688342e-06 1 0.00142903277890086 5.54724926470821 -1.80333744421713 1.16870648492684e-11 64.7963258785939 9.98317705919513 6.49055160440257 1.12638648195900e-09 -27.3874279784823 28.4125047023626 -0.963921634695055 0.336606256894426 ZSCAN9 other 1.43376911570825e-07 1 1.41879641267555e-05 6.49055160440257 -0.963921634695055 0.0237038246316553 93.4267069019338 73.5370227384081 1.27047170830235 0.205870662943706 -362.746324567793 217.985422306742 -1.66408524354141 0.0981692601467861 PIM1 og 1 1 1 1.27047170830235 -1.66408524354141 0.00195411416228806 411.06939221925 118.749296942192 3.46165748180693 0.000696128705566559 199.290288007604 329.500860745489 0.604824787275862 0.546191375048447 GMPR other 1 1 1 3.46165748180693 0.604824787275862 7.38198002739998e-16 348.746303224657 45.6666798257717 7.63677816200345 2.30620408701472e-12 -221.202410303271 137.05942655344 -1.61391606448188 0.108619722215927 CMTR1 essential 1.00431838272777e-11 1 3.11429799910468e-08 7.63677816200345 -1.61391606448188 0.042414842494029 49.7320441988945 98.3815035186996 0.505501973645298 0.613933769682119 -537.625584360391 272.518933651832 -1.97280085150802 0.0503203088295914 TFAP2A other 1 1 1 0.505501973645298 -1.97280085150802 2.60043552063305e-17 752.58185429615 125.045144935383 6.01848120280914 1.52236174709852e-08 -1532.93128312387 353.476605162582 -4.33672628042469 2.78390679172153e-05 YIPF3 other 3.60056302186852e-13 0.402246692335844 0.000183794733727204 6.01848120280914 -4.33672628042469 3.8681404115793e-05 249.844648911953 117.787567089358 2.12114618788595 0.0355107105595514 -880.194685096499 327.283226571589 -2.68939748094291 0.0079472551780763 TMEM14B other 0.298310988540996 1 1 2.12114618788595 -2.68939748094291 1.23635039057604e-11 327.131086574221 53.9782052051503 6.06042911821396 1.14473677363693e-08 -264.726237495315 164.559965128036 -1.60869162368468 0.109889322441706 TMEM63B other 1.51490013357282e-07 1 0.000139005386422733 6.06042911821396 -1.60869162368468 1.10268147419656e-36 49.5786792697607 2.97607504555464 16.659082352045 9.25263566259201e-36 -26.8103241241512 20.3784748278216 -1.3156197581356 0.190336074032445 FRS3 other 1.60451181310342e-32 1 1.34662859433364e-31 16.659082352045 -1.3156197581356 2.61912629003565e-14 269.480806416958 38.5214366265201 6.99560634328559 1.02073799833474e-10 -169.684595001075 108.852626684966 -1.55884704089102 0.121306525694946 TJAP1 other 3.46536599434616e-10 1 1.33002161183017e-06 6.99560634328559 -1.55884704089102 0.130392641651752 5.09439801989974 4.50817451739126 1.13003567192153 0.260218169936721 -14.7324224198598 13.1139779683932 -1.12341369303557 0.263010071529838 KIAA0319 other 1 1 1 1.13003567192153 -1.12341369303557 0.216455265148788 4.68563307887482 13.0787276728964 0.358263677940557 0.720713997778758 55.0634421950945 32.7418415530002 1.68174542369468 0.0949648280647596 IRF4 other 1 1 1 0.358263677940557 1.68174542369468 4.66442326643373e-08 536.234520222266 89.3928722685867 5.99862725756382 1.44511259428155e-08 342.964415447986 231.024315375545 1.48453817465264 0.139778673668918 SLC22A23 other 0.000475351375082261 1 0.000174656308144868 5.99862725756382 1.48453817465264 3.55700505308836e-05 228.754601226994 51.8650807507364 4.41057061737527 1.98050894523247e-05 83.116564417178 133.195728566815 0.624018242262809 0.533582792862573 TUBB2A other 0.276094732220718 1 0.195456427804993 4.41057061737527 0.624018242262809 1.36253043176808e-15 119.595998297147 17.3562138313071 6.89067324587927 1.40812851445328e-10 -142.914573577409 51.8261986082048 -2.75757391850815 0.00654231124020824 LRRC1 other 1.84568372287305e-11 1 1.82676512180025e-06 6.89067324587927 -2.75757391850815 0.672651808881687 -5.66599931147658 6.35898181475853 -0.891023040563883 0.37447896594775 -7.04590378721282 15.7551084631512 -0.44721391818356 0.655426857228905 FOXF2 other 1 1 1 -0.891023040563883 -0.44721391818356 4.01596402639162e-06 102.567484662576 25.6496323031251 3.99878966881251 0.000100469536705356 -72.9927695004382 65.8713225282533 -1.1081114922071 0.269623441021272 BPHL other 0.0345292586989151 1 0.919396730390711 3.99878966881251 -1.1081114922071 9.75282698862195e-07 101.788482325153 28.2167093226066 3.60738317007087 0.000424018059314984 -148.327412169079 72.1563980706287 -2.05563769998459 0.0415990650135818 RIPK1 other 0.00890823217140729 1 1 3.60738317007087 -2.05563769998459 5.97629325078583e-05 568.313249924506 133.603924547244 4.25371673661833 3.6981218934985e-05 147.54089175045 343.522541976366 0.429494061442409 0.668184140210793 TUBB2B other 0.450672274041759 1 0.354317058616092 4.25371673661833 0.429494061442409 1.09542831745468e-06 229.546042698202 70.7206295275711 3.24581447070846 0.00143881542032794 -524.709002162183 203.642228885014 -2.57662177945645 0.0109227172764388 UQCC2 other 0.00995885653537457 1 1 3.24581447070846 -2.57662177945645 2.88388357004214e-06 2790.16404192213 829.749395578352 3.36265872176662 0.00097394740728004 -5319.49671860821 2390.07656345929 -2.22565954578 0.0274895484321846 HMGA1 other 0.0251416969636273 1 1 3.36265872176662 -2.22565954578 0.0391845509120065 50.4596818760664 44.7833406316616 1.12675117944175 0.261556054136077 -225.272890186373 139.310664589958 -1.61705416343704 0.107861376343552 TCF19 other 1 1 1 1.12675117944175 -1.61705416343704 3.96448923584273e-08 712.386319704283 178.628376701089 3.98809154995774 0.000105884898861974 -1582.06965058839 535.101098768837 -2.95658082973184 0.00364012992543946 FLOT1 other 0.000406201567104446 1 0.965670277621204 3.98809154995774 -2.95658082973184 0.0220308004711573 -123.511207435066 116.953697342297 -1.05606928418498 0.292717455591063 -954.529851632216 341.042919428076 -2.79885550250669 0.00583665176943796 IER3 other 1 1 1 -1.05606928418498 -2.79885550250669 2.41584748464683e-08 256.423377731736 55.840682466206 4.59205307683909 9.58443044282196e-06 -385.462727063574 173.970110003471 -2.21568364275843 0.0283051808732107 MDC1 other 0.000251272296878117 1 0.0974895928469065 4.59205307683909 -2.21568364275843 1.38743723338898e-05 26.5782747603833 6.78007924190747 3.9200537061726 0.000133211225306111 -18.6728926026051 19.2963654957571 -0.96768962044748 0.334726576313327 PGBD1 other 0.112881893308527 1 1 3.9200537061726 -0.96768962044748 5.21595762847088e-09 154.974415300412 28.2116788932499 5.49327163005146 1.75539811673537e-07 -110.827892610485 87.3283976991282 -1.26909339379292 0.206469481463662 ATAT1 other 5.65879243112806e-05 1 0.00201133516215538 5.49327163005146 -1.26909339379292 6.9657631179753e-07 198.029474818577 40.5196250880374 4.88724844784019 2.54332408768688e-06 -43.5631309367766 113.867740802114 -0.382576580776141 0.70256123223068 TPMT other 0.00643845484994457 1 0.0270838582097776 4.88724844784019 -0.382576580776141 9.78276247731094e-07 457.021762371574 107.029517112101 4.270053483404 3.42870833591886e-05 -454.917855050405 316.097522064774 -1.43916931736397 0.152158680142135 RNF144B other 0.00893264041803262 1 0.329807454832035 4.270053483404 -1.43916931736397 0.000807919468246816 92.5235525235857 47.0628106245081 1.96595892374103 0.0512267324326463 -336.235029341445 145.095075184614 -2.31734281066143 0.0218945007255125 NRM other 1 1 1 1.96595892374103 -2.31734281066143 4.62551255241474e-10 758.228069307237 183.134036138151 4.14029027752795 5.80377236941494e-05 -1769.37240267975 527.684161089816 -3.35308984644432 0.00101484018805687 MTCH1 other 5.31101351268261e-06 1 0.544451885974816 4.14029027752795 -3.35308984644432 1.53497326295144e-12 169.577680525164 32.7884135710225 5.17187817452176 7.25527365986011e-07 -443.662746170678 112.762834138393 -3.93447672329851 0.000126806027216606 VARS2 essential 1.9379037444762e-08 1 0.00799168393633591 5.17187817452176 -3.93447672329851 1.98122159212365e-76 300.663134297943 8.17825436095658 36.7637298900025 1.28308863557015e-76 81.4761192323554 55.1416284978617 1.47757912582351 0.141631099866246 TAF8 essential 2.89654596768478e-72 1 1.87587558520356e-72 36.7637298900025 1.47757912582351 3.6619829854653e-13 259.756199576958 38.4351074981158 6.75830553068421 2.71074386955954e-10 -162.307858125313 108.514848310564 -1.49572026918192 0.136773049812885 FAM8A1 other 4.71004251590546e-09 1 3.48222157483618e-06 6.75830553068421 -1.49572026918192 0.0299832240405968 2.91168277113611 6.11687541473426 0.476008186160288 0.634743135046634 -35.9180123113169 16.9962821352095 -2.11328642497109 0.0361882429316072 C6orf52 other 1 1 1 0.476008186160288 -2.11328642497109 0.0595230368413563 -13.1217831974028 21.129867707128 -0.621006405684987 0.535537923696879 -88.9215071886702 39.9193446437641 -2.22752923381373 0.0274006963523647 FGFBP1 other 1 1 1 -0.621006405684987 -2.22752923381373 0.000315319280401326 16.5870298519281 4.85909357809249 3.41360576522166 0.00082455514735572 1.69951698471769 9.17998322984011 0.185132907344896 0.85337487868472 FGFBP2 other 1 1 1 3.41360576522166 0.185132907344896 2.56990675731215e-08 82.2221406511062 26.7308995964314 3.07592119578658 0.00249743814274698 -132.760539167177 50.146004536178 -2.64747990184135 0.00898187613569258 CPEB2 other 0.000266859117679294 1 1 3.07592119578658 -2.64747990184135 3.09810771602492e-08 285.630205749886 49.9401025988935 5.71945572567195 5.55322125489426e-08 129.427828812921 77.6862906202474 1.66603177703001 0.0977802428342261 FHDC1 other 0.000319910602756733 1 0.00065383627055125 5.71945572567195 1.66603177703001 0.443707305526648 -18.3179882193025 27.7639117070617 -0.659776922379542 0.510363695674196 -55.9773108291802 44.3308836636812 -1.26271588118692 0.208563546003618 TLR2 other 1 1 1 -0.659776922379542 -1.26271588118692 0.183834261879404 -14.7581700133708 9.69140275811721 -1.52281051378344 0.129843703283459 -2.70605117024226 15.0204993278904 -0.18015720457559 0.857264476522528 MGARP other 1 1 1 -1.52281051378344 -0.18015720457559 0.0839591981728846 30.1022915615767 13.4119736533641 2.2444341406849 0.0262678335167715 26.4657130503712 49.3949283681364 0.53579818667059 0.592891616402138 MYO7A other 1 1 1 2.2444341406849 0.53579818667059 1.05274387847368e-06 234.072991316877 48.0890299075916 4.86749247732121 2.81898438294238e-06 -141.899404694195 170.220877145396 -0.833619277927877 0.405812276583085 FCHSD2 other 0.00959154947677368 1 0.0299178812561675 4.86749247732121 -0.833619277927877 0.184039170546028 27.5227335354092 14.9174124356828 1.84500721248238 0.066957235681902 37.1402495225244 62.3589104785323 0.595588493088094 0.552324440791263 ARRB1 other 1 1 1 1.84500721248238 0.595588493088094 0.944247669752606 -1.96622322860645 64.0455028420424 -0.030700410510568 0.975547958913358 85.3528634776865 267.711755053186 0.318823741829078 0.750289401169441 SLCO2B1 other 1 1 1 -0.030700410510568 0.318823741829078 3.80924190815349e-10 394.045643153527 55.7819390771033 7.06403631126673 5.33315243864885e-11 235.06659315788 202.369133960722 1.16157335141586 0.24721771844039 THAP12 other 4.39434146524587e-06 1 6.99929025350603e-07 7.06403631126673 1.16157335141586 0.000341827484224847 52.5808364105644 16.720821452581 3.1446323710638 0.00199591713649819 -83.217883290955 58.463629701529 -1.42341287593334 0.156639297422875 ANKRD42 other 1 1 1 3.1446323710638 -1.42341287593334 6.33867540854458e-10 352.478461067563 60.658553522734 5.81086162787345 3.4913621329145e-08 -438.559932395565 218.50432814442 -2.00709952118523 0.0465001810136464 IL18BP other 7.22735770082253e-06 1 0.000415192784846192 5.81086162787345 -2.00709952118523 8.36715441775022e-09 2555.21988741465 475.668313986462 5.37185221777749 2.84733027020408e-07 -3270.52470622679 1713.45308008782 -1.90873315659111 0.0581689167200243 NUMA1 other 8.96289581229404e-05 1 0.00321976106954678 5.37185221777749 -1.90873315659111 4.45376424376023e-07 126.740872241709 30.3365989152493 4.17782074370901 4.89921710260291e-05 -236.057912745504 106.166795539827 -2.22346272716643 0.0276309155313987 CCDC90B other 0.00419143752980275 1 0.46390686744547 4.17782074370901 -2.22346272716643 0.234847985568183 -20.0989330326163 21.1059454999618 -0.952287734877961 0.342414855874945 -121.905018698435 72.7451224075258 -1.67578271455109 0.0957711409571476 SYTL2 other 1 1 1 -0.952287734877961 -1.67578271455109 0.0144478836545414 25.6121575205688 8.68750557846381 2.94816012366783 0.00369164137161728 24.716990174934 31.0270241352326 0.796627806366603 0.426885722168989 RAB30 other 1 1 1 2.94816012366783 0.796627806366603 1.4869582294827e-05 235.954558551454 57.0818640816618 4.13361690875924 5.79573429137773e-05 -186.266484183071 200.493889522889 -0.929038209724618 0.354295461278284 CREBZF other 0.120547703664163 1 0.543755791217059 4.13361690875924 -0.929038209724618 0.535645811439692 71.640694406012 90.4314076526884 0.792210320126342 0.429472704140046 -192.91413133711 328.478104152591 -0.587296775335425 0.557875788093103 LRRC32 other 1 1 1 0.792210320126342 -0.587296775335425 0.000753470521302937 395.344564262322 108.674024956888 3.63789382439049 0.000373782821083593 -55.500599089384 388.124250943673 -0.142996988604659 0.88647828338921 PRCP other 1 1 1 3.63789382439049 -0.142996988604659 1.84444718427377e-10 170.405607097779 23.9741239700454 7.10789713570738 4.4571915524055e-11 61.3507676054825 85.1225344431188 0.72073473853717 0.472194471692334 NARS2 other 2.15800320560031e-06 1 5.86031545310275e-07 7.10789713570738 0.72073473853717 0.000147188966452608 62.802110642375 16.8790403511913 3.72071571224975 0.000278476560280054 -61.9812757009967 60.8017032631241 -1.01940031898067 0.309622169774456 RNF121 other 1 1 1 3.72071571224975 -1.01940031898067 0.0413795301125293 36.9953505048519 62.8620773598265 0.588516193842724 0.557059361683089 534.785539144817 212.403878650075 2.5177767117231 0.0128456154913994 PI15 other 1 1 1 0.588516193842724 2.5177767117231 0.00200089167878532 102.523409027194 56.7416803738662 1.80684478062115 0.0728889371204437 -488.231006447996 215.035689692835 -2.27046499651013 0.0246736669987684 GGH other 1 1 1 1.80684478062115 -2.27046499651013 0.309590722052852 4.58147284238586 4.72961572924913 0.968677606100826 0.334265372185629 23.8793735421526 16.2742533758665 1.46730992756717 0.144385350811687 SLCO5A1 other 1 1 1 0.968677606100826 1.46730992756717 0.61147983978831 325.635169229305 422.481062494104 0.770768676131726 0.442056404607178 1260.88885497551 1453.72568325459 0.867349919933069 0.387135726463666 SULF1 other 1 1 1 0.770768676131726 0.867349919933069 4.82807708013131e-14 75.8807181691744 12.961378801996 5.85437084498208 2.76459064774258e-08 -25.7548489063093 19.7874250125355 -1.30157657653754 0.194992363995894 NEK1 other 6.35471505286883e-10 1 0.000330009185621031 5.85437084498208 -1.30157657653754 0.0104304669451942 173.268267860778 81.0045591706468 2.13899402249404 0.0339823671084896 -39.2845766334212 121.537598312772 -0.323229824998877 0.746951309350607 DDX60 other 1 1 1 2.13899402249404 -0.323229824998877 2.95580161717219e-07 2510.44989338065 464.21329702827 5.40796635824882 2.42380338740874e-07 254.166566439008 1298.69655047773 0.195708971695898 0.845099348606209 SORL1 other 0.00281983474278227 1 0.00275319826775759 5.40796635824882 0.195708971695898 0.0119657651170073 745.585101669046 302.481803240316 2.46489241231048 0.0148039380571431 -589.368962631087 842.859176779532 -0.699249624217178 0.485450821812265 TMPRSS4 other 1 1 1 2.46489241231048 -0.699249624217178 5.84783148837967e-11 109.835973874032 20.1957585092873 5.43856641103734 2.20677985637768e-07 -102.530123167912 55.3536464028297 -1.85227405655918 0.066005826721463 BUD13 essential 6.98874341176254e-07 1 0.00251286022245727 5.43856641103734 -1.85227405655918 0.593627731542509 -2.13519053369116 10.8875235125829 -0.196113517571142 0.844778196852071 -29.4815087497492 30.1419829034122 -0.978087899665411 0.329554954681348 TRPC6 other 1 1 1 -0.196113517571142 -0.978087899665411 0.210805537588423 -58.7805609492249 801.48687599159 -0.0733393929582468 0.94163060187242 -3580.9507204804 2249.46445665145 -1.59191255940581 0.113441723365719 MMP7 other 1 1 1 -0.0733393929582468 -1.59191255940581 0.143965529171326 -11.9852069997993 16.9306577365859 -0.707899668534446 0.480070682918524 -92.1408325415721 46.8723300987507 -1.96578306108209 0.0511104232775006 C11orf70 other 1 1 1 -0.707899668534446 -1.96578306108209 2.9120968468438e-08 96.8625481682352 27.5378743773959 3.51743009793608 0.000572877234449536 -221.891271216592 77.3040419660875 -2.87037088324481 0.00467698835171064 DCUN1D5 other 0.000301343781711397 1 1 3.51743009793608 -2.87037088324481 3.35228583333488e-13 1537.99555368555 216.151520996451 7.11535846056251 3.95729258978721e-11 -284.153756055403 601.635773678103 -0.472301961564266 0.637379865309505 YAP1 other 4.31506232466865e-09 1 5.21452444556261e-07 7.11535846056251 -0.472301961564266 0.192114387297897 602.321595904343 380.901561070841 1.58130513881596 0.115886913948239 -291.187677985085 1102.66013037354 -0.264077452302953 0.792077940593738 TRIM29 other 1 1 1 1.58130513881596 -0.264077452302953 9.27055650397875e-10 207.088552848186 45.7561331962374 4.52591900543761 1.24938337170535e-05 -408.495387311151 125.698007373083 -3.24981593462098 0.0014376665092486 SLC37A4 other 1.04822182390488e-05 1 0.125737942528426 4.52591900543761 -3.24981593462098 0.0472448080097664 196.571712502889 96.9074134144818 2.02844865606033 0.0442605304327414 -156.586091831486 278.446270970227 -0.56235657703683 0.574701501029771 POU2F3 other 1 1 1 2.02844865606033 -0.56235657703683 1.21810401300765e-14 478.018214392356 67.546463321575 7.07687998580485 4.97384186481957e-11 -206.112584187652 174.936308460843 -1.17821500865721 0.240540164495807 RDX other 1.62166187251709e-10 1 6.53562821037291e-07 7.07687998580485 -1.17821500865721 5.90925542557856e-07 119.976870583972 33.4688932230178 3.58472775853429 0.00045401696948837 -171.795351686178 87.0252519978852 -1.97408623063054 0.0501843725020542 PPP2R1B other 0.00549856217350085 1 1 3.58472775853429 -1.97408623063054 7.32985770155743e-07 74.7694414671906 20.6695383866321 3.61737355080689 0.000403669849847374 -100.876439005994 53.5045461811728 -1.88538070511643 0.0612742894879763 FDX1 other 0.00675812880083595 1 1 3.61737355080689 -1.88538070511643 0.0118406453319483 29.8489295831227 34.2648234426685 0.871124569868733 0.385069006468495 -181.470503798924 88.10983407022 -2.05959420663872 0.0411545168606783 C11orf1 other 1 1 1 0.871124569868733 -2.05959420663872 0.00850953099632087 346.321245261189 127.362541419406 2.7191766229032 0.00729609739164401 -155.294243267195 354.893040385714 -0.437580413237785 0.662303539365103 FXYD6 other 1 1 1 2.7191766229032 -0.437580413237785 0.116294437486284 10.0928903179707 16.150228341215 0.62493793305782 0.532942700829543 -59.4224574252709 41.8059959518924 -1.42138600151161 0.157239645887943 ARHGAP20 other 1 1 1 0.62493793305782 -1.42138600151161 0.319429262210481 -1.01223395540727 4.34562378979018 -0.232931796301711 0.816121676078459 -17.6717817726873 11.9631960844927 -1.47717897858368 0.141656605811341 FXYD2 other 1 1 1 -0.232931796301711 -1.47717897858368 0.612959370016682 28.6457641495502 82.9630508734795 0.345283398428002 0.730349453199052 -149.023609770839 231.187278429251 -0.644601254806693 0.520138467607537 MMP13 other 1 1 1 0.345283398428002 -0.644601254806693 0.196236885141041 40.8366802471568 36.9603575029771 1.10487784767416 0.270935757985152 -95.1876015459603 102.989258080052 -0.924247861577685 0.356803221791619 TMPRSS13 other 1 1 1 1.10487784767416 -0.924247861577685 0.31812817542793 -22.9654001273615 24.2415927789802 -0.947355247518005 0.344951644168076 -98.6844995583431 66.0752871761259 -1.49351601447143 0.13736154337234 CASP1 other 1 1 1 -0.947355247518005 -1.49351601447143 3.75498183526563e-15 30.7539987427534 4.53368720729175 6.78344079258274 2.37111733472686e-10 -25.8376056436405 12.2732790548634 -2.1051917363031 0.0368976279788662 ALKBH8 other 5.04669558659701e-11 1 3.05328779192778e-06 6.78344079258274 -2.1051917363031 2.35354212080181e-11 121.271390284002 20.0873933982648 6.03718899110513 1.1267707808002e-08 -64.9872525393574 33.7955709910091 -1.92295175473279 0.056331548311414 MAP2K5 other 2.85555265516883e-07 1 0.000136857579035992 6.03718899110513 -1.92295175473279 0.106501784791629 -153.119053261449 82.8783978381366 -1.84751463898342 0.0667103463705077 -227.958676461875 124.905615187763 -1.82504746579406 0.0700518972067832 SQOR other 1 1 1 -1.84751463898342 -1.82504746579406 4.71344972806126e-13 350.430477453581 49.7747151431448 7.04033114897383 7.71687238534087e-11 -20.6300854700854 79.4207538589653 -0.259756857844992 0.795430231677357 CTDSPL2 other 6.04358524132015e-09 1 1.00874955821176e-06 7.04033114897383 -0.259756857844992 1.62453479883388e-08 447.9167321122 85.278915805663 5.25237367150551 4.91802044605595e-07 -132.907159776715 135.978425696912 -0.977413579364112 0.329897347415346 SLTM other 0.000171047268969219 1 0.0054850682034862 5.25237367150551 -0.977413579364112 0.206926452608828 1131.27304561236 688.556912344829 1.64296229597041 0.102457801179948 1399.04316413265 970.734124891048 1.44122178077305 0.151578978284109 THBS1 other 1 1 1 1.64296229597041 1.44122178077305 1.01974107308585e-07 226.791094411332 48.5182131800807 4.67434968327404 6.89771506892407e-06 -50.6651442515333 72.7805803296876 -0.696135480399113 0.487506365389504 MAPKBP1 other 0.00101413249718388 1 0.0709981812044354 4.67434968327404 -0.696135480399113 0.0510986166491072 177.957784245675 139.160864324524 1.27879188670945 0.202919324730836 -224.021536398889 204.315461032429 -1.09644926168036 0.274616315018468 NUSAP1 other 1 1 1 1.27879188670945 -1.09644926168036 1.17246909213881e-09 42.2267686067529 12.7508838064735 3.31167386101619 0.00115873450396125 -62.1917175094259 18.7207999615123 -3.32206517014681 0.00111926467539925 NDUFAF1 other 1.31879323483774e-05 1 1 3.31167386101619 -3.32206517014681 0.0156340916004616 152.814150737354 56.2897215968303 2.71477894013885 0.00739931806075602 -0.84883153386675 97.2305732275724 -0.00873008875387397 0.993045932968543 KIF23 essential 1 1 1 2.71477894013885 -0.00873008875387397 0.31793052101064 -72.9071775529081 120.144274521682 -0.60683022843299 0.544857178781248 216.012938315914 202.823858912015 1.06502725800923 0.288530581986612 ITGA11 other 1 1 1 -0.60683022843299 1.06502725800923 7.58697993456962e-05 103.329646017699 25.9296721161457 3.98499624502998 0.000104419921999018 12.4293931731986 37.6522716933903 0.330110046862872 0.741771340478883 KNL1 other 0.565381744724128 1 0.953667147617029 3.98499624502998 0.330110046862872 5.3945123047389e-09 109.161897785056 24.6659699714252 4.42560734126882 1.92879342544759e-05 -70.5487407102938 37.9137491436653 -1.86076930674848 0.0648894547479804 HAUS2 other 5.8449540821846e-05 1 0.190487638697204 4.42560734126882 -1.86076930674848 4.96056118556108e-16 555.05463015605 89.7743501010386 6.1827752529687 5.54190453637655e-09 -363.920606096605 131.806365380184 -2.76102451537077 0.00647209919142383 RTF1 essential 6.76422123263109e-12 1 6.81765096065044e-05 6.1827752529687 -2.76102451537077 2.38148426957649e-07 537.193466320228 104.014236257788 5.1646148224254 7.7093035244682e-07 -91.3676644159263 181.431158753595 -0.503594118251839 0.615300456694025 PARP6 other 0.00229456009373695 1 0.00847715015550524 5.1646148224254 -0.503594118251839 1.53613561290958e-05 8708.4225103959 3668.33372099263 2.37394500412014 0.0188482994366906 -20070.9682695822 6470.86644339183 -3.1017435524541 0.00229388162751164 RPLP1 essential 0.12436553922116 1 1 2.37394500412014 -3.1017435524541 2.14892238581229e-10 176.851725873382 25.7816591154665 6.85959445361249 1.63353199872996e-10 23.0625720498723 44.5332722110289 0.517872837652399 0.605299926283571 PAQR5 other 2.50650307081145e-06 1 2.11477052555581e-06 6.85959445361249 0.517872837652399 0.00340479122367826 39.3648828195335 12.3009376727023 3.20015301816302 0.00167233050918952 2.95852958178938 21.4358554169648 0.138017798881398 0.890409019866065 LRRC49 other 1 1 1 3.20015301816302 0.138017798881398 8.73787159723461e-19 485.167414418288 57.4960442019444 8.43827468745896 4.06207879686933e-14 -119.648392846169 93.6719743010813 -1.27731259791316 0.203652336218807 TUBGCP4 essential 1.22496221921632e-14 1 5.60688736331874e-10 8.43827468745896 -1.27731259791316 1.4088051105206e-09 149.211286144962 40.2399528820042 3.70803829175683 0.000293415708293855 -195.374011844133 63.1076853793384 -3.09588302390978 0.00234216222442533 RMDN3 other 1.57772084327203e-05 1 1 3.70803829175683 -3.09588302390978 0.277052234134345 5.92062341428054 3.69625992238523 1.60178762819794 0.111292510325929 3.9072472773089 5.42556546938251 0.720154848256505 0.472542935166287 ITPKA other 1 1 1 1.60178762819794 0.720154848256505 0.00121908560830932 293.149729437742 113.866688552187 2.57449947096149 0.0109934478802954 -289.900038854825 198.426326314117 -1.46099584787908 0.146080661755315 UACA other 1 1 1 2.57449947096149 -1.46099584787908 1.65310717784785e-08 477.981295411162 96.573603595322 4.9493989829154 1.92254018472065e-06 -283.910080352783 162.711753863161 -1.74486522093265 0.0829903039493183 SMAD6 other 0.000173989530468487 1 0.0206500041240845 4.9493989829154 -1.74486522093265 0.62483029109486 15.313615475741 46.2541713193846 0.331075339562364 0.741055864625922 -40.1164130335733 66.4853145576019 -0.60338757965591 0.547174496769464 PLCB2 other 1 1 1 0.331075339562364 -0.60338757965591 0.061924411555255 21.1249715197084 25.1620804658449 0.83955583674345 0.402675441388937 -56.4975241133135 39.5648768031859 -1.42797169303366 0.155661688004747 TMEM62 other 1 1 1 0.83955583674345 -1.42797169303366 2.56655806114097e-05 395.159330063525 103.821754919211 3.80613225398683 0.000203265418293116 -157.005996998325 165.545242380619 -0.948417452175029 0.344402892133377 ADAM10 other 0.203143070539308 1 1 3.80613225398683 -0.948417452175029 0.0876934478500881 49.6985084816013 61.9868282188608 0.80175917867789 0.424101283001985 -150.400765568905 103.735974220926 -1.44984193476215 0.149421823487408 DUOX1 other 1 1 1 0.80175917867789 -1.44984193476215 0.684700767083288 20.2331724266786 24.2397033935947 0.834712046518901 0.405301961417368 7.22392238554577 40.1176103913376 0.18006861114304 0.857359084186357 SLC28A2 other 1 1 1 0.834712046518901 0.18006861114304 0.129721288536269 262.021968277339 134.355804691193 1.95020951182256 0.05305374486164 52.9986531254191 234.794269352441 0.225723793308877 0.82172977628355 STRA6 other 1 1 1 1.95020951182256 0.225723793308877 0.034756970729799 83.8277316484172 45.489273742978 1.84280215424097 0.0673451494314728 -51.1591077001115 68.0842606846897 -0.751408727738684 0.453591900535902 SEMA6D other 1 1 1 1.84280215424097 -0.751408727738684 4.00076663243809e-07 50.8468130690949 9.68388239545817 5.25066404079242 5.02665886291057e-07 5.75284951703761 14.505202581277 0.396605940854854 0.692214327200441 BCL2L10 other 0.00377912416100102 1 0.00560271396860012 5.25066404079242 0.396605940854854 8.73857916042695e-08 371.853384153713 114.084099324266 3.25946723825884 0.00137208806394383 -538.978202229081 169.660629297551 -3.17680185709921 0.00179732997443199 RSL24D1 essential 0.0008737032014412 1 1 3.25946723825884 -3.17680185709921 0.000340427470019152 43.4921282477016 13.8830916787175 3.13274083714179 0.00216874173189733 -12.8351232390317 22.4369557197936 -0.572052795366918 0.568338782725031 SPTBN5 other 1 1 1 3.13274083714179 -0.572052795366918 0.0502372432931529 35.0017833637638 41.5240273632465 0.842928434122561 0.400610564769131 -102.875059632787 65.1214791977233 -1.57974083052437 0.116272676205606 GCHFR other 1 1 1 0.842928434122561 -1.57974083052437 0.00288134496650473 115.793373561114 35.9117698149253 3.22438504584615 0.00154151735613309 -57.6099338205245 115.767170047105 -0.497636193379204 0.619450309271638 BCAR3 other 1 1 1 3.22438504584615 -0.497636193379204 0.0897206277047316 -2.36650599364514 14.78292434945 -0.160083751881825 0.87302488275845 -98.4744999277872 45.9350554410193 -2.14377666430007 0.0336206054828642 TTLL7 other 1 1 1 -0.160083751881825 -2.14377666430007 3.12493576500621e-11 678.136039897388 97.3233713701079 6.96786424833688 8.8133601501505e-11 -336.486124610293 313.789057984963 -1.07233224374069 0.285248371321518 FNBP1L other 3.77210996193899e-07 1 1.15067230120365e-06 6.96786424833688 -1.07233224374069 7.11983793120684e-06 101.824881841744 32.3362828640521 3.14893589562645 0.00196629027216045 -325.797326828277 106.150987648249 -3.06918789967237 0.00253458245112704 KYAT3 other 0.0596144029979949 1 1 3.14893589562645 -3.06918789967237 0.00010887181782247 30.4808659856685 23.5689650321424 1.29326281167204 0.197844299790007 -291.007978858566 77.3703312321733 -3.76123475528763 0.000239227349299263 GTF2B essential 0.795526372828789 1 1 1.29326281167204 -3.76123475528763 5.38320853450814e-05 123.416233746272 53.4138902231054 2.31056440994605 0.0221754257756536 -479.163701546218 158.98682845915 -3.01385785344686 0.00301419593281114 RABGGTB essential 0.408529818631769 1 1 2.31056440994605 -3.01385785344686 0.0265606498644594 556.509877482687 321.809308532653 1.72931566218576 0.0857307435207877 -1391.40416254471 958.369577345152 -1.45184508715222 0.148552858320141 IFI44L other 1 1 1 1.72931566218576 -1.45184508715222 0.344665348987189 12.5663572026482 8.62037862844046 1.45775002981761 0.146919634698592 8.39114222661899 25.6720623165423 0.326858906898647 0.74421274904213 GIPC2 other 1 1 1 1.45775002981761 0.326858906898647 0.000148105464127598 505.928293316027 152.967836235849 3.3074161586229 0.00117365118242957 -888.09062546798 475.075554503247 -1.86936712918558 0.0634829265381976 ARHGAP29 other 1 1 1 3.3074161586229 -1.86936712918558 0.00908596980464889 155.88617475776 121.563512288126 1.28234345835848 0.201649116665446 -850.295904589536 372.185090142439 -2.28460496433137 0.0237017217573645 IFI44 other 1 1 1 1.28234345835848 -2.28460496433137 0.29641310414778 25.1865178379629 23.3341721006366 1.0793833922771 0.282093610752323 -50.2758398466546 71.4648911567445 -0.703504042794724 0.48279711261305 SLC44A5 other 1 1 1 1.0793833922771 -0.703504042794724 4.58375739756313e-14 239.233490195353 31.2156791374139 7.66388868690724 1.93214686228355e-12 -145.585463605854 95.9811088635984 -1.516813728551 0.131377160533315 DBT other 6.03589174111113e-10 1 2.61206934312113e-08 7.66388868690724 -1.516813728551 9.67803159548234e-09 96.8883814243318 23.5032852476623 4.12233355479395 6.12916651934025e-05 -248.946830246942 72.2672529429058 -3.44480826528194 0.000737631442278965 RTCA other 0.000103254919092201 1 0.573996444536215 4.12233355479395 -3.44480826528194 0.000251766686552495 187.824299206812 45.2955637509131 4.14663785265342 5.88374537327596e-05 26.8985605913241 174.256226151118 0.154362120570643 0.877551386621365 IFT172 other 1 1 0.551718803652087 4.14663785265342 0.154362120570643 8.69812922887944e-14 352.599996915954 42.0589913574244 8.38346297749985 3.23408263819558e-14 45.2811813661887 147.856798976776 0.306250248074835 0.759833193441421 SELENOI other 1.13693247150683e-09 1 4.46982561425011e-10 8.38346297749985 0.306250248074835 0.984299925456269 5.38202358835686 35.6469416204132 0.150981356147391 0.880207751394787 -8.00795211268465 130.707140425959 -0.0612663706557091 0.951234449139565 CGREF1 other 1 1 1 0.150981356147391 -0.0612663706557091 3.05974820189769e-06 316.058907112698 64.7607706475134 4.88040682580781 2.66414882201264e-06 -176.659870947404 229.594182843779 -0.769444019701524 0.442831713861051 HADHB other 0.0266009948401467 1 0.0283252302756384 4.88040682580781 -0.769444019701524 0.602146389417124 7.59603207342077 14.081876071133 0.539419040122939 0.590454607395291 48.7956719550273 51.6342123453454 0.945025976743229 0.346273740308837 KHK other 1 1 1 0.539419040122939 0.945025976743229 0.00765240249983913 187.938551813323 65.4331432593238 2.87222258402729 0.00465495705736442 -118.291784546262 219.136610071658 -0.539808407675832 0.590113957789762 ADCY3 other 1 1 1 2.87222258402729 -0.539808407675832 1.05218937018773e-14 236.982053600583 27.1994421827455 8.71275418107349 4.37985511341991e-15 4.84575389948012 123.002871086339 0.039395453591313 0.968626129964969 PPM1B other 1.40277886833428e-10 1 6.11164982526614e-11 8.71275418107349 0.039395453591313 2.23119350066526e-06 183.906270111817 35.1787659686459 5.22776353996409 5.43356731504364e-07 22.1198799207777 149.584385720528 0.147875594195405 0.882631909176593 PNPT1 essential 0.0197081321913763 1 0.00604049678413402 5.22776353996409 0.147875594195405 1.37304477306853e-08 90.5855185492175 14.9436547430629 6.06180483333694 9.95950689038956e-09 -39.3769497400347 67.5790490690934 -0.582679843567721 0.560961036431641 DYNC2LI1 other 0.000145213215199728 1 0.000121247036883603 6.06180483333694 -0.582679843567721 0.00327104056109801 24.9688451132904 8.00882046520836 3.11766822864356 0.00218308766509144 -25.1327819964952 33.018125437034 -0.761181371256943 0.447735836068054 THUMPD2 other 1 1 1 3.11766822864356 -0.761181371256943 0.591726853159303 83.309230485136 166.566981014009 0.500154532296705 0.617680221166073 631.950188033287 658.368782441359 0.959872650233951 0.338623923918633 CYP1B1 other 1 1 1 0.500154532296705 0.959872650233951 4.49250488029022e-06 302.850596032073 59.3325330230905 5.10429237723953 1.0634246317275e-06 28.2197956719549 217.555430372068 0.129713129310047 0.896979574594662 PREB essential 0.0383929467069602 1 0.0116040895814105 5.10429237723953 0.129713129310047 6.07696147838423e-12 424.141582278481 55.1196997628644 7.69491822530275 2.23395764018077e-12 -79.5248734177215 207.610477959109 -0.383048457859554 0.702260702719439 SLC5A6 other 7.52753218327455e-08 1 3.01695979306412e-08 7.69491822530275 -0.383048457859554 1.27291570606279e-07 433.317992221186 75.6474352194272 5.72812536161046 5.22456097043894e-08 -42.9338722678297 308.664737275819 -0.139095488026106 0.889557613137888 PREPL other 0.00125547676088973 1 0.00061608022963416 5.72812536161046 -0.139095488026106 0.847433699120682 7.65374893373918 97.7689790015322 0.0782840223136547 0.937704414898426 -213.185603718805 398.92742073406 -0.534396967063645 0.59384259742136 SLC3A1 other 1 1 1 0.0782840223136547 -0.534396967063645 0.81828920832692 -140.791092188502 249.227321633513 -0.564910344763623 0.573038826784647 151.467509552472 913.845313116086 0.165747427248917 0.868594834404701 EMILIN1 other 1 1 1 -0.564910344763623 0.165747427248917 0.423709259872376 53.3011785605281 49.7216121083459 1.07199216397856 0.285411547260882 -96.935449159904 202.879427357127 -0.477798318058485 0.633475670993435 SIX3 other 1 1 1 1.07199216397856 -0.477798318058485 0.00135586030402825 703.22411392405 230.002025125661 3.05746922680287 0.00267126752332229 -1336.34867088608 866.311510645645 -1.54257291339708 0.125175802211642 ATRAID other 1 1 1 3.05746922680287 -1.54257291339708 6.91942886133885e-12 276.160570765272 41.4642655735712 6.66020649214859 4.63115048573241e-10 -303.313563398994 138.864467520573 -2.18424172010783 0.0304669384743688 CENPO other 8.55241407261482e-08 1 5.90517998435739e-06 6.66020649214859 -2.18424172010783 2.10006671841405e-10 922.817879838242 131.940457459492 6.99419948670075 7.64376336393956e-11 -14.9592720970547 596.668673236899 -0.0250713214352304 0.980030532837234 LRPPRC essential 2.45119787373288e-06 1 9.99269184567819e-07 6.99419948670075 -0.0250713214352304 0.59029208829326 -0.0678415441246509 3.95535252660409 -0.0171518325277815 0.986339734971002 -15.0910530029944 14.8711336232367 -1.01478833996986 0.311944903901563 TRIM54 other 1 1 1 -0.0171518325277815 -1.01478833996986 4.25435751919565e-07 141.477309176022 25.8036367238311 5.48284378245643 1.73335300326775e-07 -18.9998036751004 88.8953527660314 -0.213732249031139 0.831046104137959 DTNB other 0.00401058283334574 1 0.00198728921824647 5.48284378245643 -0.213732249031139 2.6074779403957e-07 375.09287084399 111.284395090646 3.37057923115331 0.000949645985239267 -357.455155777727 199.764702710091 -1.78938096134273 0.0755316246779027 ACTR1A essential 0.00250291807498583 1 1 3.37057923115331 -1.78938096134273 0.00075487308497794 50.5319706536175 15.1496025976873 3.33553110240209 0.00106695025916736 9.97015646195687 27.0380724125891 0.368745090619504 0.712824180041827 MFSD13A other 1 1 1 3.33553110240209 0.368745090619504 0.183888262831084 1.14729604383032 2.67645543273983 0.428662487630462 0.668752705367904 -6.01959510737655 4.75685737211419 -1.26545629529799 0.207570771999683 CYP2C8 other 1 1 1 0.428662487630462 -1.26545629529799 0.00444390019281779 417.662488864476 402.791540285878 1.03691971427216 0.301398693526377 -1424.88580274646 715.830103880774 -1.99053629488567 0.0483014401221501 MYOF other 1 1 1 1.03691971427216 -1.99053629488567 0.130044408252038 -72.5062480614814 57.6129989846041 -1.25850501344075 0.210065620301163 -203.243415928594 100.079995735341 -2.03080959821447 0.0439509561680859 LOXL4 other 1 1 1 -1.25850501344075 -2.03080959821447 0.918293973972914 -1.37355970536996 8.17815270078234 -0.1679547638232 0.866833658581796 -5.94616787391628 14.6134743462537 -0.406896247464973 0.684634866630234 STAMBPL1 other 1 1 1 -0.1679547638232 -0.406896247464973 0.287563040623158 -2.63978069629181 5.02568762810951 -0.525257614804205 0.600140431506153 8.51294140971512 9.01127738418206 0.944698631146157 0.346255158137839 CH25H other 1 1 1 -0.525257614804205 0.944698631146157 1.88891568101847e-11 180.090641211228 49.2855016578954 3.65402877424862 0.000351475359298745 -308.944260420262 88.1744415308731 -3.50378471421438 0.000597797608750817 ATAD1 other 2.29975484163999e-07 1 1 3.65402877424862 -3.50378471421438 0.000187561150256509 113.468844958435 86.8738734599947 1.30613313806811 0.193417655829919 -393.134335978745 153.714694473556 -2.55755858166428 0.0114880976433509 KIF11 essential 1 1 1 1.30613313806811 -2.55755858166428 0.000127046173765926 14.2085368977799 4.13023358594561 3.44012913606843 0.000746077761156583 -5.91534968498991 7.50176082739255 -0.788528163066745 0.431584478336504 CUZD1 other 0.919433159544003 1 1 3.44012913606843 -0.788528163066745 0.0166819985167424 132.563911430985 58.0506252130658 2.28359145046982 0.0237538800865861 -56.4963968347224 105.278517550997 -0.536637465543296 0.592287461596129 TACC2 other 1 1 1 2.28359145046982 -0.536637465543296 0.0541966355129848 -60.9723844003485 67.4697278585078 -0.903699871566326 0.367584562225161 -291.357307181156 120.740441786242 -2.41308796680546 0.0170082839679776 DUSP5 other 1 1 1 -0.903699871566326 -2.41308796680546 0.000516645429796801 15.866610507984 100.357145019443 0.158101453612596 0.874582642834282 -547.339412984013 173.908567209676 -3.1472826311317 0.00197676319350418 CALHM2 other 1 1 1 0.158101453612596 -3.1472826311317 3.40049126997684e-06 82.5946316829511 54.0644678361862 1.52770636591135 0.128650163677847 -298.742462499626 95.4869717672618 -3.12862013498319 0.00210332398697345 ARL3 other 0.0294380529241895 1 1 1.52770636591135 -3.12862013498319 0.013928843217782 59.4671043004327 74.8394656048068 0.794595522828175 0.428071654221 -247.820401572195 133.002650453502 -1.86327415827576 0.0643280893035254 CEP55 essential 1 1 1 0.794595522828175 -1.86327415827576 5.2295400960421e-06 92.5227619376608 33.8333582349747 2.7346609016783 0.00696263133358782 -117.291844923339 60.8865238520866 -1.92640074523353 0.0558608844153927 KIF20B other 0.0443935658753014 1 1 2.7346609016783 -1.92640074523353 0.92173509072869 -4.75982444415137 19.472596805115 -0.244437066703968 0.807209481503761 4.41532682580095 34.6451108737192 0.127444442071343 0.898750698833741 ENTPD1 other 1 1 1 -0.244437066703968 0.127444442071343 3.28994783466175e-05 32.1374314535238 18.476880108887 1.73933214179737 0.0839488568547748 -83.6576750740313 32.7400548257033 -2.55520876551355 0.0115689533931613 EXOC6 other 0.256561175885688 1 1 1.73933214179737 -2.55520876551355 0.0101306312103719 54.2901518726464 57.576950013576 0.942914688253639 0.347164082590095 -188.911813708023 101.037180987942 -1.86972569761787 0.0633722117347405 PLCE1 other 1 1 1 0.942914688253639 -1.86972569761787 0.0236811483874533 -7.55073876410184 14.1481963669866 -0.533689140880227 0.594321131169498 -63.4956631154678 25.2005643430136 -2.51961274561975 0.0127612335133169 RBP4 other 1 1 1 -0.533689140880227 -2.51961274561975 2.7125459031411e-10 84.1005917487002 12.4506853341454 6.7546957851435 2.71913694293631e-10 -51.2226081185711 48.8958745246544 -1.04758547866331 0.296460425044691 DBR1 essential 3.15089332108871e-06 1 3.49273140320169e-06 6.7546957851435 -1.04758547866331 1.22809500313293e-09 289.544756684099 42.2656847974077 6.85058713876222 1.8401042464452e-10 94.0962237204123 169.508387549663 0.555112493727449 0.579655752339624 DNAJC13 other 1.38013316452078e-05 1 2.37888676980435e-06 6.85058713876222 0.555112493727449 0.996620138054718 -0.205210201121527 2.59620197997101 -0.0790424638393576 0.93710146249082 0.174528032526635 10.9224042237612 0.0159789025338356 0.987271905534854 GPR87 other 1 1 1 -0.0790424638393576 0.0159789025338356 0.000374324041392357 180.499574591712 89.607740310267 2.0143301679825 0.0457503824561684 -452.921358262949 192.762645929548 -2.34963239936272 0.0200863705765962 ANXA7 other 1 1 1 2.0143301679825 -2.34963239936272 1.68103331620241e-11 260.314677623525 42.9610581555785 6.05931717698445 1.04376434887774e-08 -153.684063444631 92.4170971539793 -1.66293973926245 0.0983987736658752 FAM149B1 other 2.05035633577208e-07 1 0.000126911307180045 6.05931717698445 -1.66293973926245 1.28216286138973e-09 229.224753073977 41.9852874026896 5.4596447292461 1.91731894672351e-07 -136.593198375903 96.2678750923732 -1.41888660412247 0.157992889277294 ASCC1 other 1.43935602819611e-05 1 0.00219149555610497 5.4596447292461 -1.41888660412247 0.648726859994403 0.155486184909656 3.67878786399698 0.0422656023282413 0.966342435106466 -6.84002580841052 7.94830032449167 -0.860564589807188 0.390833270087201 ZNF365 other 1 1 1 0.0422656023282413 -0.860564589807188 0.238751051570325 1.82378615364454 35.8059478323625 0.0509352848913038 0.959441834543331 -120.513885617066 78.6642580395774 -1.53200308018456 0.127534214681364 ADAMTS14 other 1 1 1 0.0509352848913038 -1.53200308018456 1.03927653388981e-07 2221.04789808917 1158.88521803981 1.91653829345234 0.0572110397253568 -12656.8405095541 2883.02602480694 -4.39012357177792 2.13532257544632e-05 RPS24 essential 0.0010328330193797 0.309045236344346 1 1.91653829345234 -4.39012357177792 1.08169011680034e-06 109.091994124128 20.6142339054879 5.29207122730307 4.09470215773086e-07 32.7908556738888 44.3579949123155 0.739232143804247 0.460891317741959 TET1 og 0.00984121668264947 1 0.00458565694644279 5.29207122730307 0.739232143804247 0.00351927270977216 62.6450605949321 21.2617437762845 2.94637454265659 0.00371521186450226 -20.8994491369813 45.7513156481798 -0.456805423863537 0.64845457760604 DNA2 other 1 1 1 2.94637454265659 -0.456805423863537 0.703301067066886 2.73331056207062 30.7974991920948 0.0887510555653239 0.929396583567058 -70.2821802218934 92.7456732526493 -0.757794706287129 0.449747133641047 AOX1 other 1 1 1 0.0887510555653239 -0.757794706287129 3.49123812537344e-09 468.727858190396 86.6304194279098 5.41066130449076 2.37483462485643e-07 -284.515523709325 231.234819478692 -1.23041817123715 0.220428914558992 ATIC other 3.82779348065943e-05 1 0.00269971200153678 5.41066130449076 -1.23041817123715 2.06206718129526e-11 177.736011266314 25.6052105188175 6.94140011603083 1.1565534036798e-10 -6.80249561956551 68.7315450691495 -0.0989719584031123 0.92129537082765 SMARCAL1 other 2.50706127901878e-07 1 1.50375073546447e-06 6.94140011603083 -0.0989719584031123 0.0228949072599956 53.5953861584752 26.0973062948725 2.05367502503526 0.0417094950847576 -56.0566532932133 68.1491006820559 -0.822558958697651 0.412038966157801 BARD1 other 1 1 1 2.05367502503526 -0.822558958697651 0.970761162727747 -0.578698855278377 2.67251492485111 -0.216537183720542 0.828861310860622 0.412983601000017 9.56452486930314 0.0431786844243008 0.965616141073207 STAT4 other 1 1 1 -0.216537183720542 0.0431786844243008 4.14955993295923e-06 38.9057762404632 9.94094183349578 3.91369116650206 0.000135770963888985 -50.7054522368293 29.4294366597496 -1.72295014760438 0.0868918757024712 CARF other 0.0356198224645221 1 1 3.91369116650206 -1.72295014760438 0.000585134220839632 118.739161827973 34.273287240661 3.46448127354133 0.000691659813003097 -92.6450073708595 123.610561852281 -0.749491030398954 0.454727363995891 ASNSD1 other 1 1 1 3.46448127354133 -0.749491030398954 0.00119031822088384 148.674659664849 58.093660378634 2.55922347973668 0.0114736700180217 -332.045827340536 177.003512865082 -1.87592789524824 0.0625954077135744 METTL5 other 1 1 1 2.55922347973668 -1.87592789524824 1.04015361839876e-09 464.294246914405 95.5153965589898 4.86093618035349 2.90089282172662e-06 -948.098260695055 291.02247325184 -3.25781803068729 0.00138679302190612 SSB other 1.17350131227749e-05 1 0.0307639683744108 4.86093618035349 -3.25781803068729 0.00234894394404891 307.809302101924 110.151609151858 2.79441493839249 0.0058696646792103 -465.202838207465 386.025600308302 -1.20510877474428 0.230034166840289 NAB1 other 1 1 1 2.79441493839249 -1.20510877474428 0.757747652880258 -0.949560515340914 2.88560118838037 -0.329068521029368 0.742548107164079 4.2809855840275 8.54261284505225 0.501133044617254 0.616988436883853 CDK15 other 1 1 1 -0.329068521029368 0.501133044617254 2.92211163178763e-11 436.598720614431 76.7486141803988 5.68868539551996 6.44259160426994e-08 -721.613840933567 232.361619713607 -3.10556382686168 0.00226877014865855 PPIG other 3.53341738515761e-07 1 0.000756553532089419 5.68868539551996 -3.10556382686168 0.000115235207834573 54.00728755359 18.5984294709844 2.90386280399898 0.00423925554987589 -129.522536556292 56.3080029803445 -2.30025093593721 0.0228034076800623 FASTKD1 other 0.839603724282699 1 1 2.90386280399898 -2.30025093593721 0.00189702819450093 26.4273035439137 11.5397073447517 2.29011904326437 0.0233543987499492 -52.988813559322 32.6245420557618 -1.62420099165694 0.106351753547998 MDH1B other 1 1 1 2.29011904326437 -1.62420099165694 0.286632482464617 13.841179138322 9.39702253229113 1.47293241989783 0.142810185446016 33.4462585034013 32.4323427675472 1.03126248828588 0.304034620024721 HECW2 other 1 1 1 1.47293241989783 1.03126248828588 0.0210486737393097 327.387736239922 151.982129220636 2.15411994764624 0.0328066525781968 -369.381064686447 442.306809172775 -0.835124074570055 0.404958573911362 IDH1 other 1 1 1 2.15411994764624 -0.835124074570055 0.00702598738007343 249.547734603668 121.240924803702 2.05827970223506 0.0412485818394018 -704.425669016189 412.244792434563 -1.70875577313206 0.0895107746287153 OLA1 other 1 1 1 2.05827970223506 -1.70875577313206 5.90277276356154e-09 145.454624873066 34.0535509469257 4.27134970739954 3.38786804579581e-05 -398.048914342035 115.7892771315 -3.43770100481738 0.000754640000672923 CIR1 other 6.37971680285731e-05 1 0.326116178088304 4.27134970739954 -3.43770100481738 0.000389040949828027 454.292977052209 113.323518684097 4.00881460730675 9.45718147376776e-05 221.016633297397 378.250632520784 0.584312660165221 0.559859445049204 SSFA2 other 1 1 0.867601828403455 4.00881460730675 0.584312660165221 0.657894461543903 -5.33074420069275 18.9227672052005 -0.281710605160735 0.778546089431755 49.9559147685525 65.9312771085781 0.757696755764086 0.449797951323322 CHRNA1 other 1 1 1 -0.281710605160735 0.757696755764086 2.87557678259845e-18 363.410915419727 38.6655116378197 9.398838914219 6.93091702240466e-17 -52.0563804634566 114.466440375688 -0.454774170425876 0.649908007234742 FAM117B other 4.01976878439438e-14 1 9.79407884436003e-13 9.398838914219 -0.454774170425876 6.40787844682933e-13 159.063882557984 24.3070390726828 6.54394317968353 8.40229741276731e-10 -160.50261429146 71.4936709147946 -2.24499053185764 0.0261929755626389 WDR12 essential 8.18216865257792e-09 1 1.06347878353396e-05 6.54394317968353 -2.24499053185764 4.87781238461253e-07 441.489461204057 101.95453621368 4.33025814838455 2.6630291956484e-05 -535.359372941642 301.722922149564 -1.77434107136303 0.0779699013884416 ABI2 other 0.0045709979856204 1 0.259485564823981 4.33025814838455 -1.77434107136303 0.080540507952027 410.011331896896 209.643555963162 1.95575451872674 0.0522578881704052 -306.647491364275 701.455411054764 -0.437158922052045 0.662593008931792 ITGAV other 1 1 1 1.95575451872674 -0.437158922052045 0.26371328175464 -856.13618256317 614.074773319918 -1.39418881830071 0.165268830741165 888.040621443205 2249.61474313994 0.394752312213116 0.693571873177986 SLC40A1 other 1 1 1 -1.39418881830071 0.394752312213116 0.049282002834845 28.0099379524302 16.7278111708019 1.67445326028794 0.0961392816158694 -110.947149258876 72.6011661199798 -1.52817310228222 0.128589675467583 DIRC2 other 1 1 1 1.67445326028794 -1.52817310228222 4.01380967271714e-06 78.9421514179962 15.3000138281155 5.15961307648829 7.52014133297228e-07 33.3621155942592 68.0370735236258 0.49035200761059 0.624582738518242 SENP7 other 0.0345147493756947 1 0.00827516352280269 5.15961307648829 0.49035200761059 0.266709926335609 142.778522478586 148.162223206979 0.963663472295011 0.336706096299573 -805.489401998021 683.59243706745 -1.17831818832505 0.240464047530595 PARP9 other 1 1 1 0.963663472295011 -1.17831818832505 0.00293946668808767 53.1683222621734 30.8078569266597 1.72580398528675 0.0864015350605678 -93.0285678122227 47.1846361152847 -1.97158599644446 0.0504603502402224 MNS1 other 1 1 1 1.72580398528675 -1.97158599644446 2.47856652561212e-12 275.995335820896 51.1233864567813 5.39861216068339 2.51268312737333e-07 -212.2158424927 76.6474456756228 -2.76872687174484 0.00632364651139664 USP8 essential 3.11010527633809e-08 1 0.00285063900800505 5.39861216068339 -2.76872687174484 3.24515044325052e-07 159.823248803362 59.3056182466827 2.69490907486327 0.00784426424239418 -281.825685297836 89.4429916826116 -3.15089734808842 0.00196538390357883 SECISBP2L other 0.00308776064675287 1 1 2.69490907486327 -3.15089734808842 3.72212767726577e-06 219.585417153539 91.9946327107215 2.38693726669934 0.018210820169104 -419.717406545618 137.156133084597 -3.06014318941712 0.00261323258699014 TMOD3 other 0.0320842294403288 1 1 2.38693726669934 -3.06014318941712 1.03263299061833e-05 183.892562231932 55.4363398802632 3.31718440699947 0.00113448250368537 -147.550557181224 82.9306749330387 -1.77920362158347 0.0771789250934716 SPPL2A other 0.0852438533755432 1 1 3.31718440699947 -1.77920362158347 0.244863480595238 127.50380540382 77.0184768026307 1.65549632629796 0.099860264971857 121.146178098765 132.922246951507 0.911406336239275 0.363505753250718 GLCE other 1 1 1 1.65549632629796 0.911406336239275 5.53917794778026e-05 67.135330542775 23.4258744662918 2.86586230278738 0.00481051688038764 -69.7379412137775 38.8813323558099 -1.79360986335534 0.0750652741395769 SHF other 0.419371162426443 1 1 2.86586230278738 -1.79360986335534 0.00259411844732135 63.9499605831028 26.4407383291375 2.41861478250138 0.016769662440107 -53.5166419475954 43.4123161065395 -1.23275251696451 0.219583940562703 APH1B other 1 1 1 2.41861478250138 -1.23275251696451 2.0345991837507e-12 329.597011341386 48.4774574119844 6.79897480060299 2.11226530818119e-10 -100.370527171303 80.4003840585704 -1.24838367809517 0.213760922292049 INTS14 other 2.55871193348488e-08 1 2.72461102102291e-06 6.79897480060299 -1.24838367809517 0.151022260301506 116.743119435516 89.6841047831685 1.30171472099509 0.194932874443999 275.689855554325 148.742051532043 1.85347622084487 0.065702840104438 CILP other 1 1 1 1.30171472099509 1.85347622084487 5.95625178083828e-05 63.0415235139828 18.2035412317772 3.46314613795769 0.000689273115939984 -41.1138128486458 30.1907687489214 -1.36180079383088 0.175224113123471 PARP16 other 0.449458759382056 1 1 3.46314613795769 -1.36180079383088 5.25886776397981e-07 51.9269810282254 12.1740349117828 4.26538788532364 3.55550666498701e-05 -31.9043757202566 20.9659200488098 -1.52172552628177 0.130226068219313 PPCDC other 0.00491283426510994 1 0.341648635438601 4.26538788532364 -1.52172552628177 0.00499683185753385 20.5324401103394 6.82847734240894 3.00688412375927 0.00309556257363963 28.8736077700206 11.9055421501292 2.42522410201263 0.0164868920241575 HCN4 other 1 1 1 3.00688412375927 2.42522410201263 0.0252836463833884 50.9028323068624 20.6873463824254 2.46057814114361 0.0150295015306882 77.8005573464788 36.3971133847182 2.13754746218815 0.0342075858714737 SEMA7A other 1 1 1 2.46057814114361 2.13754746218815 1.33519114362257e-11 550.456348371391 85.5877207468131 6.4314874092717 1.62027880460724e-09 -170.568143655755 148.654097171059 -1.14741636390606 0.253048616813861 UBL7 other 1.63373988333658e-07 1 2.03069542581425e-05 6.4314874092717 -1.14741636390606 0.696143729396755 6.5136779822871 16.5325276185647 0.393991658902342 0.694128694142748 -8.03435879191849 24.6627497446142 -0.325768978524911 0.745038524957483 ARHGAP24 other 1 1 1 0.393991658902342 -0.325768978524911 2.10355171830541e-05 28.9906103286392 54.5109577012033 0.531830874950841 0.595604563274675 -264.243740219092 81.4606786349254 -3.24381952921517 0.00144459517132133 FAM13A other 0.167968604706687 1 1 0.531830874950841 -3.24381952921517 0.0123710710176484 88.1381944444447 138.698247588025 0.635467253387666 0.526054775241304 -370.392129629629 207.470877504412 -1.78527287340245 0.0761600744307492 HERC6 other 1 1 1 0.635467253387666 -1.78527287340245 0.0664206527039818 61.7252314814815 83.4080595427605 0.740039173910251 0.46038849491602 -147.766820987654 124.765406955083 -1.18435730379056 0.23807299318393 HERC5 other 1 1 1 0.740039173910251 -1.18435730379056 0.00117682088270176 179.558748678595 68.7405971400015 2.6121208739705 0.00988902271673506 -40.3269122848234 103.592382563975 -0.389284533154926 0.697603448193084 PCDH10 other 1 1 1 2.6121208739705 -0.389284533154926 1.13178568425961e-08 55.5109745390694 10.5051129540184 5.28418635592447 4.27702009479099e-07 10.9652856167342 15.8727474934398 0.690824674257946 0.490722473165047 ZGRF1 other 0.000120240911095741 1 0.00478684089009008 5.28418635592447 0.690824674257946 2.79516718380071e-14 123.722156967432 23.7486329427979 5.2096538468313 5.98398609196479e-07 -67.0610061484938 35.8298300198826 -1.87165292470772 0.0631512442778616 AP1AR other 3.69604956713968e-10 1 0.00663444538016136 5.2096538468313 -1.87165292470772 2.96024140351666e-08 148.243987133031 42.8702430668439 3.45796936354868 0.000706165477456741 -132.813664325545 65.6533852037908 -2.02295226534452 0.0448310630822282 COPS4 essential 0.000306118563537658 1 1 3.45796936354868 -2.02295226534452 4.06747418953048e-09 861.006172576518 219.266953361035 3.9267484651863 0.000129564800848911 -679.61580660764 351.21921691245 -1.93501885398557 0.0548205423032515 HNRNPD other 4.43842783561566e-05 1 1 3.9267484651863 -1.93501885398557 0.0172495202493734 14.5319885212694 5.15231424769163 2.82047791005374 0.00543109997804506 9.84239956110736 8.16686503768446 1.20516250919924 0.230001267823019 PRKG2 other 1 1 1 2.82047791005374 1.20516250919924 3.57343013042834e-05 172.968404363074 55.8645898099908 3.09620825913842 0.00233195192886714 -87.8000885644917 89.4278736625571 -0.981797788190652 0.32774943540229 RASGEF1B other 0.277190975217326 1 1 3.09620825913842 -0.981797788190652 1.76170819588119e-10 1201.51662575318 245.922957670826 4.8857440441223 2.57407983101718e-06 -464.388286154076 376.908368576801 -1.23209863423197 0.219802381487168 SEC31A other 2.0626079557377e-06 1 0.0273959316415159 4.8857440441223 -1.23209863423197 0.0156488828189729 19.7763327957543 7.81019959761871 2.53211618327706 0.0123460259926485 4.8363243317435 12.0166792932724 0.402467621354524 0.687901654717864 GPAT3 other 1 1 1 2.53211618327706 0.402467621354524 0.000205714621154524 24.6390008058018 13.5455243271009 1.81897726590811 0.0708203576064868 -36.4917908944399 20.3857844146017 -1.79006066935065 0.0753713951460338 FGF2 other 1 1 1 1.81897726590811 -1.79006066935065 4.53525387156387e-15 80.0194296653572 11.6286219477282 6.88124784046233 1.31352638749551e-10 -2.38868653970466 17.5189427761041 -0.136348783726998 0.891719134742452 BBS7 other 6.08812479718734e-11 1 1.70535130888543e-06 6.88124784046233 -0.136348783726998 2.4166347675806e-10 416.49293918751 65.050861591148 6.40257375536722 1.66271455054547e-09 160.687795236438 98.0014938033335 1.63964638701224 0.103068240481661 KIAA1109 other 2.81223787903355e-06 1 2.08354760328853e-05 6.40257375536722 1.63964638701224 2.19246412558344e-07 256.35271929223 55.8324226020147 4.59146688152091 9.00771510221223e-06 38.4202043755575 84.937461404396 0.45233520922688 0.651655885146787 BMPR1B ts 0.00211967431661407 1 0.091806632321747 4.59146688152091 0.45233520922688 2.92394045457091e-11 122.024677121771 40.1347720693489 3.04037299404428 0.00277203330274288 -179.838917309628 60.2185027295529 -2.98643953532525 0.0032785903520328 RAP1GDS1 og 3.53533640362168e-07 1 1 3.04037299404428 -2.98643953532525 4.33552352298207e-13 161.54704595186 32.7264404163897 4.93628527564996 2.03755660214942e-06 -89.9478378659991 48.5522140513 -1.85260012593783 0.0658413786399925 LARP1B other 5.56594509880438e-09 1 0.0218466818882461 4.93628527564996 -1.85260012593783 0.256312060368971 -7.02802721355175 7.45662220144714 -0.942521563206969 0.347392393563733 -18.4233360782159 11.1940838494594 -1.64581008378865 0.101829128560683 MMRN1 other 1 1 1 -0.942521563206969 -1.64581008378865 0.296032104449621 2.60822209511499 26.6404472773509 0.0979045910138468 0.922134544799437 -44.6072056178454 39.6115813904484 -1.12611524337177 0.261857273237923 PDE5A other 1 1 1 0.0979045910138468 -1.12611524337177 3.42163232305808e-05 13.8412570507655 7.48736957756677 1.84861411038609 0.0663944569618179 -24.1625453263498 11.2683642474688 -2.14428152975063 0.033549306114325 PRDM5 other 0.266374076350071 1 1 1.84861411038609 -2.14428152975063 3.00628674712918e-07 51.9615120165213 11.3914553154422 4.56144632776486 1.03071726363066e-05 -78.0013880328364 45.9919606346775 -1.69597875273063 0.091910520774374 NAAA other 0.00286589315603824 1 0.104545652050058 4.56144632776486 -1.69597875273063 2.51448927092728e-47 292.742247944482 15.103300343961 19.3826674486767 3.71959108010369e-43 -143.766016005175 58.8391598757815 -2.4433730241677 0.015680682402348 NUP54 essential 3.66713115272034e-43 1 5.42167595835914e-39 19.3826674486767 -2.4433730241677 0.8840257752219 36.1064805027578 77.4756184897851 0.466036686206233 0.641852031550671 97.9844637057251 306.083419351208 0.320123396142851 0.74931154386136 CXCL9 other 1 1 1 0.466036686206233 0.320123396142851 6.61408976115343e-06 172.116588154448 64.3237306048304 2.6757867825148 0.00826201023928707 -183.858598332819 106.082106745935 -1.73317257709782 0.0850666567526656 BMP2K other 0.0555517399039276 1 1 2.6757867825148 -1.73317257709782 1.79744805801803e-55 1064.49148122858 45.0800450991283 23.6133632716611 4.75358327759446e-53 -56.6491350945294 182.020089465799 -0.311224630538233 0.756050750055127 G3BP2 other 2.62337544067731e-51 1 6.93737943532136e-49 23.6133632716611 -0.311224630538233 0.0327081619495504 219.379376702638 139.81152111526 1.56910800306494 0.118715938358043 -174.815721812768 227.089061402536 -0.769811283436901 0.442614454525099 SEPT11 other 1 1 1 1.56910800306494 -0.769811283436901 4.66135056759606e-06 542.198761609907 110.287566544642 4.91622744609597 2.25110171525063e-06 336.764583026193 185.229509396925 1.81809358629 0.0710058564505553 FRAS1 other 0.0397286908876212 1 0.0240485196240225 4.91622744609597 1.81809358629 1.47224509806463e-37 1843.84935101043 111.427045259528 16.5475926128694 6.5867684368988e-36 -50.4379687318327 435.127549910523 -0.115915364913586 0.907871619660631 SCARB2 other 2.14285274023307e-33 1 9.58770013674989e-32 16.5475926128694 -0.115915364913586 3.88892328648783e-17 353.759895673519 63.7799545284832 5.54656864039523 1.25000473466121e-07 -325.513347652655 104.645537207803 -3.11062809115554 0.00222753725386224 CCNG2 other 5.37215862795429e-13 1 0.00144488047279489 5.54656864039523 -3.11062809115554 5.34750361374196e-10 120.415181138585 37.1462645123568 3.24164980568985 0.00145675948935538 -180.432719953997 60.794312047172 -2.96792107482019 0.00347766910261697 CNOT6L other 6.12235688737317e-06 1 1 3.24164980568985 -2.96792107482019 1.82039475356533e-59 762.521859410474 29.8659093359103 25.5315132325011 3.2363429499684e-57 3.39843955733243 120.589841410894 0.0281818063409893 0.977553635456045 USO1 other 2.65886857705752e-55 1 4.72570797554386e-53 25.5315132325011 0.0281818063409893 3.44979803931401e-05 7.74296123748796 2.10888640098619 3.67158763690026 0.000331888437533733 -12.6133592421516 8.51506892986971 -1.48129854802533 0.140570206387746 CDKL2 other 0.268325291497844 1 1 3.67158763690026 -1.48129854802533 0.000938580352600176 134.439022654262 58.1450001642431 2.31213384254038 0.0221399979109037 -475.727900768009 227.858436331852 -2.08782219533518 0.0385157725943243 SHROOM3 other 1 1 1 2.31213384254038 -2.08782219533518 1.71382380034838e-06 571.940637720487 162.183933075224 3.52649382016904 0.000555046177206639 -276.891721206801 266.640506321004 -1.03844582740725 0.30069025626474 ANXA3 other 0.0153027327133107 1 1 3.52649382016904 -1.03844582740725 7.89440151205099e-08 199.694807849549 76.0339401581106 2.62639036506972 0.00948975328637784 -264.92244480785 114.200878625732 -2.3197934026066 0.0216484574605599 PPA2 essential 0.000791887415673835 1 1 2.62639036506972 -2.3197934026066 0.000586207829897979 91.4306883365196 26.4645715397708 3.45483350067157 0.000708212684585623 39.2782026768637 39.0483235979502 1.0058870409209 0.316017691098777 CENPE essential 1 1 1 3.45483350067157 1.0058870409209 1.89514970777494e-13 132.076246933769 20.0552623298127 6.58561552383359 6.5573391636915e-10 12.9626737530663 30.12245024224 0.430332647205739 0.667547598146038 GSTCD other 2.45497693145166e-09 1 8.32191913264089e-06 6.58561552383359 0.430332647205739 3.98208294792924e-15 116.334968656309 22.2153363369368 5.23669625757062 5.21473664720147e-07 -69.526001635323 33.3668217557668 -2.0836866676793 0.0388193216828425 INTS12 essential 5.35032664883773e-11 1 0.00580452336199996 5.23669625757062 -2.0836866676793 0.0278971412992385 39.0107202154064 17.8381419159031 2.1869273380221 0.0302370144795304 6.63241587353549 26.8257333775294 0.247240803455205 0.805046957997826 ENPEP other 1 1 1 2.1869273380221 0.247240803455205 7.68351312422881e-08 174.399715662562 47.7854972456088 3.64963693411369 0.000360491386833127 -87.2990565166815 72.3707247786299 -1.206275835757 0.229585331800434 CASP6 other 0.000771885728460027 1 1 3.64963693411369 -1.206275835757 5.25732542492381e-07 879.780361757106 163.298370144414 5.38756364181141 2.56809774435707e-07 577.197028423773 245.478549889667 2.35131350043904 0.0199492470844843 LEF1 other 0.00491244487704881 1 0.00291196603232648 5.38756364181141 2.35131350043904 3.92655797869706e-05 259.503875968993 127.48852281917 2.03550774791763 0.0434813653484716 -339.37633236434 191.647336599556 -1.7708377188328 0.0785281631501605 HADH other 0.302580557838396 1 1 2.03550774791763 -1.7708377188328 0.157429345584156 -5.40925180688842 14.3406437457527 -0.377197279479903 0.706539635969273 -36.04064657667 21.623721001458 -1.666718071984 0.0975769771059874 EGF other 1 1 1 -0.377197279479903 -1.666718071984 3.19886439902321e-11 451.732558139536 108.217245264438 4.17431211666578 4.93761034852687e-05 -308.465358527131 162.677756165452 -1.89617416540591 0.0597740695151399 PAPSS1 other 3.8597497838614e-07 1 0.467443571695039 4.17431211666578 -1.89617416540591 3.73414119016924e-18 332.658708857184 46.8468987323713 7.10097611279691 4.28014963247871e-11 -58.0429297923437 70.9707540448837 -0.817842935072043 0.414710457704783 SEC24B other 5.21360792971429e-14 1 5.63396096123172e-07 7.10097611279691 -0.817842935072043 2.15941613615019e-07 218.714960134284 79.5361550318828 2.74988098238607 0.00666629611032621 -217.252727654218 116.961424869764 -1.85747333273452 0.0651290021410717 PPP3CA other 0.00208966699495254 1 1 2.74988098238607 -1.85747333273452 0.595578785406311 93.6612015245928 172.178102493617 0.543978590587993 0.587232819511376 -63.0685008167468 253.830192377469 -0.248467293138076 0.804099662707622 SLC39A8 other 1 1 1 0.543978590587993 -0.248467293138076 0.00516630610293425 595.9882859734 189.62585488659 3.14296954036065 0.00200432914803105 251.849229141476 280.426278272081 0.898094253838515 0.370528241192765 FBN2 other 1 1 1 3.14296954036065 0.898094253838515 1.40442304424431e-05 327.579134369894 81.4794987814319 4.02038720499033 9.51728286687519e-05 -67.3058085482215 179.752290449914 -0.374436444619188 0.70865437438344 MAPK8IP3 other 0.114207681957947 1 0.872925184549792 4.02038720499033 -0.374436444619188 2.65694433002917e-07 296.641185926058 68.6036940238206 4.32398269724452 2.70379859370661e-05 -135.823897124486 110.109796042056 -1.23353145684339 0.219209436904156 RGS3 other 0.00254800961249798 1 0.263322945041086 4.32398269724452 -1.23353145684339 5.25627136922912e-73 1041.71718180093 30.1984960380686 34.4956643035377 8.87520659311314e-74 -45.3702250250936 166.485300109135 -0.272517903955198 0.785593685527238 GUCD1 other 7.6830918604022e-69 1 1.29728894771535e-69 34.4956643035377 -0.272517903955198 6.34301141105722e-17 454.528589580687 50.370952305537 9.02362510090409 7.4934165219658e-16 13.2386995751671 86.5786184397141 0.152909572984067 0.878672385349687 RNF185 other 8.74701273584791e-13 1 1.05200074551878e-11 9.02362510090409 0.152909572984067 0.00929573564495263 -5.29837279979748 20.8706049262306 -0.253867715790949 0.799934202974085 -86.4667278713438 32.5909529328637 -2.65308989428638 0.00880650637319128 KIAA1644 other 1 1 1 -0.253867715790949 -2.65308989428638 0.530668829179031 -58.26964353552 55.0782333674788 -1.0579432195428 0.291727310701912 -80.7236450550844 86.0086287699658 -0.938552866259311 0.349420576485752 PARVG other 1 1 1 -1.0579432195428 -0.938552866259311 0.000337222577014007 104.263106177299 32.0818477373037 3.24990963834247 0.00145034361525452 -154.266239974504 130.664375452828 -1.18062968150181 0.239780784181327 B4GALNT3 other 1 1 1 3.24990963834247 -1.18062968150181 0.333821670788345 120.608744927221 173.36476799139 0.695693515612184 0.487711760804541 -667.322989347879 666.976160237405 -1.00052000225968 0.318691942711732 ERP27 other 1 1 1 0.695693515612184 -1.00052000225968 5.07866609296724e-07 190.543897842505 44.2756761444345 4.30357962735385 2.95611303980745e-05 -402.031116476325 203.734779203058 -1.97330626635734 0.0502274139062258 ETV6 other 0.00474906066353366 1 0.286565598078934 4.30357962735385 -1.97330626635734 2.07663671314429e-06 122.087453042254 25.4615996380727 4.79496397624982 3.78637208869798e-06 -81.7817911304249 111.309520789045 -0.73472413276685 0.463617638023354 GABARAPL1 other 0.0183906947316059 1 0.0398477798614576 4.79496397624982 -0.73472413276685 0.0116442899940714 47.02110295685 20.6123314605158 2.2812122465099 0.0240783629201626 -105.652529005146 76.9271798567901 -1.37340962195458 0.171868454939855 KIF21A other 1 1 1 2.2812122465099 -1.37340962195458 0.187959571016883 -13.1877435044792 8.23989011133864 -1.60047565274348 0.111813530790587 -38.927103754622 30.591940041063 -1.27246273699448 0.205379963265958 CPNE8 other 1 1 1 -1.60047565274348 -1.27246273699448 2.70528766692364e-18 145.103850992183 14.5557117738305 9.96885987073906 5.78528807702427e-18 -160.567228021732 90.2788983847943 -1.778568756315 0.0775123088125507 YARS2 essential 3.78280374465932e-14 1 8.21858024222068e-14 9.96885987073906 -1.778568756315 4.1492203171487e-35 246.92422834955 14.6261748175558 16.8823517720551 9.17119613704222e-36 -47.505452058295 122.821210802685 -0.386785407405024 0.699494095019386 FGD4 other 6.03379618519764e-31 1 1.3348675977465e-31 16.8823517720551 -0.386785407405024 4.76006854273815e-10 45.3001600555374 6.80611474850751 6.65580316074911 6.35286945872004e-10 -36.2715351832926 29.5159611366353 -1.22887867399555 0.221239398765378 ALG10 other 5.4626546596463e-06 1 8.06750892562858e-06 6.65580316074911 -1.22887867399555 7.55196025718219e-19 240.713082312967 26.2327541992434 9.17605069161629 4.13659998453525e-16 -201.650276527951 112.353117517588 -1.79479022018578 0.0747702497822156 AEBP2 other 1.05946450448009e-14 1 5.81605957825656e-12 9.17605069161629 -1.79479022018578 1.90252146707142e-16 82.54793086678 8.63294126353399 9.56197063629599 3.82591731065177e-17 -17.1463550198923 72.9087790671993 -0.235175451286719 0.814399851253155 ETFBKMT other 2.6077861749148e-12 1 5.41329040284119e-13 9.56197063629599 -0.235175451286719 1.09533487010025e-20 366.976189517752 34.4856155528515 10.6414278427287 5.04161047251245e-20 -43.9385717736093 174.856022459079 -0.251284291817242 0.801940540975841 ETNK1 other 1.55340391277617e-16 1 7.21908203559057e-16 10.6414278427287 -0.251284291817242 1.52154737464699e-07 271.115500228366 65.6047464080341 4.13255922890306 6.04067542177582e-05 -536.254750549673 202.556314567133 -2.64743536480539 0.0090076113771968 ZCRB1 essential 0.00149172504610391 1 0.565950880266176 4.13255922890306 -2.64743536480539 0.00100728874233404 11.4997473233116 7.71126920729986 1.4912911239599 0.138042546088067 -71.7252831663423 25.6728523770949 -2.79381823697685 0.00590835891019175 TMEM117 other 1 1 1 1.4912911239599 -2.79381823697685 0.261156890993175 104.213240995465 66.9847664580073 1.55577523825205 0.12194150923485 0.509989696963301 206.817161390817 0.00246589641562474 0.99803589061871 PRICKLE1 other 1 1 1 1.55577523825205 0.00246589641562474 3.45516324363219e-05 516.298975003186 122.394714236288 4.21831104574051 4.27097972567395e-05 -380.551564804194 502.350403025333 -0.757542071256193 0.449929614454596 C1RL other 0.268708045457275 1 0.406639979681417 4.21831104574051 -0.757542071256193 6.00474880819447e-14 335.139518379267 48.1954095474615 6.95376430091813 9.34336922424197e-11 -529.490605312604 218.982881283198 -2.41795432688568 0.0167678512083827 NDUFA9 other 7.88543613492098e-10 1 1.21856221422564e-06 6.95376430091813 -2.41795432688568 5.50747584752284e-14 904.371283095723 105.486223331674 8.57335919831123 1.38047792931534e-14 449.215388096854 432.097385008657 1.03961607656537 0.300248734418537 CLSTN3 other 7.23847550639927e-10 1 1.91706970044021e-10 8.57335919831123 1.03961607656537 9.43274343627322e-11 12.0226065038795 1.7254579841904 6.96777702733837 8.97800158779834e-11 -0.473191953620546 7.52620671149872 -0.0628725693778238 0.949950040827943 KLRG1 other 1.1179687520671e-06 1 1.17162920720768e-06 6.96777702733837 -0.0628725693778238 0.000662433862876343 43.1787029170207 14.8456524359293 2.90850827226157 0.00418011530206755 -99.962212242586 65.9553363299616 -1.51560461677422 0.131709927528502 VAMP1 other 1 1 1 2.90850827226157 -1.51560461677422 0.00624438035977762 98.2074532710279 60.5045050651262 1.62314282490731 0.106644748577523 -568.625996884735 270.312973904666 -2.10358381497914 0.0370723962010723 TAPBPL other 1 1 1 1.62314282490731 -2.10358381497914 0.0556990322117967 14.5006979016424 7.31244564676662 1.98301616204891 0.0491794818427122 -21.6844299251361 32.7142502576935 -0.662843554546585 0.50844129121075 CD27 other 1 1 1 1.98301616204891 -0.662843554546585 0.05196269582444 9.78851930744442 4.49404682331339 2.17810799314892 0.0309813406599008 -8.48271341962967 18.4451285089635 -0.459889092966061 0.646270709989574 RBP5 other 1 1 1 2.17810799314892 -0.459889092966061 5.95942430587091e-30 286.267344310231 20.2890339795617 14.1094615248121 7.17161035113503e-29 -65.1318620113481 92.6801848868658 -0.702759301687348 0.483348224710329 PEX5 other 8.63460987677636e-26 1 1.03988350091458e-24 14.1094615248121 -0.702759301687348 0.120041231961699 61.5794119462562 31.0047774489692 1.98612655896691 0.0488915684158623 5.64303718030489 135.932898364912 0.0415134029229346 0.966943325115359 PIANP other 1 1 1 1.98612655896691 0.0415134029229346 3.89708661688787e-07 18.5308411214953 3.29860093276884 5.61778811659419 9.13825124197253e-08 10.4454672897196 11.212514217307 0.931590104349356 0.353045376126867 SLC38A4 other 0.0036839159789441 1 0.0010641493571277 5.61778811659419 0.931590104349356 0.852993988723949 13.9228971962617 24.677033287153 0.564204660837818 0.573457503861831 15.6957067757009 83.8814977054242 0.187117626712165 0.851821263501475 AMIGO2 other 1 1 1 0.564204660837818 0.187117626712165 1.3997471220409e-18 629.811528150135 64.99701019241 9.6898538299794 2.218349488624e-17 -138.139356568365 212.983218784181 -0.648592679540368 0.517641882961243 SCAF11 other 1.96006589499387e-14 1 3.14229205063589e-13 9.6898538299794 -0.648592679540368 0.00523775745634631 581.447280966769 186.236406032945 3.12209247027626 0.00217635175367493 91.0102719033229 541.778635732203 0.167984239135462 0.866834692981452 COL2A1 other 1 1 1 3.12209247027626 0.167984239135462 0.417058588439884 -11.3250421511117 14.9536545159574 -0.757342771228698 0.450040540575062 -41.9200665636306 31.6216949449559 -1.32567424474245 0.186976515493562 PPFIA2 other 1 1 1 -0.757342771228698 -1.32567424474245 1.34553535358857e-36 123.938205529592 7.54132503614218 16.4345396777902 1.89987637074027e-35 -114.435475467638 48.062032647336 -2.38099533382887 0.018512732119055 LLPH other 1.95761938593601e-32 1 2.76451010706416e-31 16.4345396777902 -2.38099533382887 0.0165066072960527 104.846962347947 39.0889766901775 2.68226418867326 0.0081497506592055 -53.0293862752284 124.747642269143 -0.425093294836125 0.671390273984642 LRIG3 other 1 1 1 2.68226418867326 -0.425093294836125 2.07571690375205e-08 123.399322175146 23.7824600543159 5.18866937622598 7.5267595779527e-07 -171.132980471675 78.5729340597221 -2.17801438268297 0.0311291339085614 MARCH9 other 0.000217016202287277 1 0.00828169356362136 5.18866937622598 -2.17801438268297 0.196539200733851 2.58557219309152 3.80730249871904 0.679108684944637 0.498240308632066 -18.1411968214498 12.772918277553 -1.42028598533595 0.157846979852941 INHBE other 1 1 1 0.679108684944637 -1.42028598533595 0.104304632680686 28.1068924374416 35.3099330983534 0.796005258892782 0.427262283274382 -102.338874769135 76.3726407531501 -1.33999392661978 0.182234006401037 GLIPR1 other 1 1 1 0.796005258892782 -1.33999392661978 0.512427430830603 19.2157886578179 179.857927523328 0.10683870832063 0.915056899462359 -370.267637004462 391.492955869882 -0.94578365064511 0.345750206023681 PHLDA1 other 1 1 1 0.10683870832063 -0.94578365064511 0.00497762643003431 69.9668020952521 29.846504339516 2.34422099483918 0.0203438684383096 -157.851114068032 104.202349626525 -1.51485177286109 0.131859735452449 TMEM19 other 1 1 1 2.34422099483918 -1.51485177286109 0.172400874341183 98.731835318849 133.684058091126 0.73854606696296 0.461314083135387 -665.259132112964 466.867922828291 -1.42494075858289 0.156211009703307 LGR5 other 1 1 1 0.73854606696296 -1.42494075858289 0.012751552784859 28.5445632477168 10.9317219538526 2.61116806375203 0.00995232017678897 3.66752012693722 23.1609621000871 0.158349213261889 0.874397488801458 PTPRQ other 1 1 1 2.61116806375203 0.158349213261889 0.0348856299446589 523.630745020459 278.900474571361 1.87748244539641 0.0624066455133683 -268.858277505507 582.702418919344 -0.461398938422327 0.64518527278526 DUSP6 other 1 1 1 1.87748244539641 -0.461398938422327 0.000152116366243582 35.450195584731 49.8784434786908 0.710731793382367 0.478361483609343 -326.248129580505 104.210255330807 -3.13067201058912 0.00209932884525837 POC1B other 1 1 1 0.710731793382367 -3.13067201058912 7.56822401441011e-06 11.7082614591309 23.7746543717389 0.492468209045708 0.623118157948688 -194.884647670353 49.7631228712085 -3.91624633716683 0.000136890657997683 TMTC3 other 0.0632098069683533 1 1 0.492468209045708 -3.91624633716683 0.00365601569442586 -679.306559052911 819.619823371733 -0.828806892759616 0.408521855759754 3787.61563875744 1710.23258256824 2.21467868017671 0.0282800625736236 LUM other 1 1 1 -0.828806892759616 2.21467868017671 1.51913085344271e-07 18.3093752998751 95.9576616015071 0.190806809944059 0.848925045873636 -923.645489061455 190.939258572857 -4.83737863006845 3.13173194383775e-06 SNRPF essential 0.00148965971488592 0.0456011488342214 1 0.190806809944059 -4.83737863006845 1.38322625327254e-11 80.5745310957551 20.5946950856556 3.91239252441645 0.000137110558482872 -141.804351127648 41.032001608307 -3.45594525174077 0.00070994704083377 NEDD1 essential 1.69140906250166e-07 1 1 3.91239252441645 -3.45594525174077 0.0152586587514454 0.365361262902277 6.50505308846055 0.0561657618983002 0.955281627904908 -31.6030109841585 13.0271537136205 -2.42593368274423 0.0164097185261548 SYCP3 other 1 1 1 0.0561657618983002 -2.42593368274423 0.00268488162345547 32.3716516380272 16.6415567469603 1.94522977208489 0.0535453543416889 -46.6220911548422 33.2831134939205 -1.4007731326986 0.163267938370666 GAS2L3 other 1 1 1 1.94522977208489 -1.4007731326986 8.83479658547236e-05 219.070014967571 54.2442331911533 4.03858626216693 8.50484936822494e-05 41.3545763627429 123.991067101699 0.333528675326453 0.739194900080049 TMEM132B other 0.652449727837134 1 0.783806917775611 4.03858626216693 0.333528675326453 4.19760282900413e-08 79.3819715070593 21.6355447470704 3.66905351517938 0.000338333603995263 -91.1076311250238 41.8304961239235 -2.17801937742063 0.0309773741762595 SLC15A4 other 0.000429330817350543 1 1 3.66905351517938 -2.17801937742063 4.02212715138239e-10 104.311803653228 31.4822786782548 3.31334986006835 0.00114598920958719 -218.412486616942 64.578569596498 -3.38212022938313 0.000909310055476974 TDG other 4.63398565014242e-06 1 1 3.31334986006835 -3.38212022938313 1.58195635702248e-09 129.836623469018 40.9007489325815 3.1744314433712 0.00181116045591462 -296.665169815385 82.1688878860293 -3.61043184893616 0.000412219232475436 RITA1 other 1.76688705515841e-05 1 1 3.1744314433712 -3.61043184893616 0.067328518761319 -17.3594531706378 22.0110217276817 -0.788670938832705 0.431508963319646 -101.890265353876 44.219756943328 -2.30417967888106 0.022540498042221 SDSL other 1 1 1 -0.788670938832705 -2.30417967888106 4.31050833638467e-06 25.5503650046605 28.7806311115713 0.887762499217328 0.376052938872179 -222.473270875218 57.3305340515894 -3.88053721381739 0.000154147659186008 MMAB other 0.0369238144094711 1 1 0.887762499217328 -3.88053721381739 0.000497053489009481 62.8835955299987 55.9130906619547 1.1246667781287 0.262491578446691 -297.079649922245 110.498638740835 -2.68853673952508 0.00797211842150074 GLTP other 1 1 1 1.1246667781287 -2.68853673952508 2.08655883080288e-05 116.355180644461 43.8388765554539 2.65415516515981 0.0087910525986481 -176.746186394705 86.6368881769096 -2.04008004112285 0.0430622012741185 GIT2 other 0.16671605058115 1 1 2.65415516515981 -2.04008004112285 2.70921917283895e-08 95.7382553976349 35.560897197493 2.69223396884329 0.00788829458253151 -239.97016382771 70.277473239366 -3.41461001323096 0.000817879009448317 TCHP other 0.000280973120415127 1 1 2.69223396884329 -3.41461001323096 0.0179632388287791 25.0932413788242 27.6217564571217 0.908459294316688 0.365055088827175 -101.58182430087 55.0220751932381 -1.84620125547998 0.0667826908491749 FAM222A other 1 1 1 0.908459294316688 -1.84620125547998 0.00819048670887959 -4.57485247136623 16.5461475402973 -0.276490491833486 0.782539699988753 -92.742794464363 32.9513112607763 -2.81454032983385 0.00551879440109878 FOXN4 other 1 1 1 -0.276490491833486 -2.81454032983385 3.30313584016076e-10 227.592312705959 47.3058947497275 4.81107722219481 3.5302276309652e-06 -141.88142715849 77.5705581783019 -1.82906286212825 0.0693120444747134 NUP58 other 3.821728167066e-06 1 0.0372156596856351 4.81107722219481 -1.82906286212825 3.45180050821059e-07 57.1237870383453 29.0572315905809 1.96590603823602 0.0510960739403966 -166.128850825657 47.6470360728254 -3.48665655869423 0.000636481549281672 MTMR6 other 0.00327610386234267 1 1 1.96590603823602 -3.48665655869423 0.00157083486053608 -25.3441363211522 21.9172954641225 -1.15635327190069 0.249315847069912 -128.62927902833 36.1319225129308 -3.55998989487194 0.000492712508239773 SLC46A3 other 1 1 1 -1.15635327190069 -3.55998989487194 2.62505665367524e-07 778.068233753562 174.257771221656 4.46504180731118 1.52796111314078e-05 -214.474948862129 293.54197548172 -0.730644905247922 0.466091981353758 SLC7A1 other 0.00251874185920139 1 0.15238356181353 4.46504180731118 -0.730644905247922 1.43834853102438e-14 155.027907974424 21.520724690461 7.20365648481811 2.39302958346535e-11 -19.882339249611 35.1501324989813 -0.565640520706065 0.572456087407556 LNX2 other 1.91257204170312e-10 1 3.16813186554978e-07 7.20365648481811 -0.565640520706065 1.8760599685874e-08 122.57975296644 23.2400578313521 5.27450292318436 5.15942193026773e-07 -97.4013903475082 63.7917924927921 -1.52686398267479 0.129134360664765 SUOX other 0.000196798690704819 1 0.00574553226154614 5.27450292318436 -1.52686398267479 0.109817948130224 -12.6280637661906 20.4033636555995 -0.618920682851473 0.536960249772556 -117.247772453385 55.5496746436867 -2.11068333352895 0.0365523080100504 CCDC65 other 1 1 1 -0.618920682851473 -2.11068333352895 0.688758759020676 2.38804282069491 10.2378420015381 0.233256463650849 0.815920877515732 -19.0545727136432 27.6882728685064 -0.688182061919668 0.492536688153954 SLC39A5 other 1 1 1 0.233256463650849 -0.688182061919668 1.03510071226971e-10 200.294448612153 42.4573372168848 4.71754617085355 5.65182630921735e-06 -439.814718679669 113.650395796867 -3.86989165850131 0.000165405995628724 TARBP2 other 1.22493818289998e-06 1 0.05863769795813 4.71754617085355 -3.86989165850131 0.905950521351651 -0.457245456028423 16.7394195499996 -0.0273154905200064 0.978243238929427 17.5894670867927 43.5387608593663 0.403995583236924 0.686772819141654 ACVRL1 other 1 1 1 -0.0273154905200064 0.403995583236924 0.373773599073036 -4.37816879148666 5.89291083747001 -0.742955207068146 0.458727585350223 15.4020313981667 17.0802864075938 0.901743157615849 0.368709609453495 GPR84 other 1 1 1 -0.742955207068146 0.901743157615849 1.26156534132968e-07 194.077066729793 42.2147730884891 4.59737320683865 9.83692592371232e-06 -214.251874062968 114.169974119601 -1.87660438495436 0.0627634482156307 NABP2 other 0.00124478652229 1 0.099982515088612 4.59737320683865 -1.87660438495436 0.000205132214876948 94.5443724153348 32.4151976796208 2.91666808111969 0.00407075142341696 -56.1557132744679 54.5963310916747 -1.02856203249583 0.305308828785508 N4BP2L1 other 1 1 1 2.91666808111969 -1.02856203249583 7.56379064311071e-09 889.461680035163 155.777715891815 5.70981333846798 7.1339182386712e-08 -434.627974947807 424.738785494684 -1.02328299131337 0.308045734058637 SMARCC2 other 8.11746011818642e-05 1 0.000834953790654078 5.70981333846798 -1.02328299131337 5.08734490413065e-10 92.888391232539 15.1320800355229 6.13850779367286 6.84829708827328e-09 9.52733299741524 25.3858839779586 0.375300423088965 0.707956821046638 BRCA2 ts 5.82958852564331e-06 1 8.40012120847601e-05 6.13850779367286 0.375300423088965 7.28887741489523e-06 53.3417721518988 22.2211902512393 2.40049122251333 0.0176069082382555 -197.871308016878 60.5336390488316 -3.26878263269878 0.00134127662836757 KANSL2 essential 0.0609548147490693 1 1 2.40049122251333 -3.26878263269878 5.15099746617859e-14 171.172973988168 28.0001004628307 6.11329856531747 7.68631744683904e-09 -234.777590209365 71.3135182775442 -3.2921891372073 0.00123292235805976 CERS5 other 6.7751069672647e-10 1 9.40113486922883e-05 6.11329856531747 -3.2921891372073 2.93643873963643e-05 338.024381095273 99.0303169461874 3.41334241390901 0.000836488288752653 -539.990942735683 265.085741466318 -2.03704258006761 0.0435035302420047 MAP3K12 other 0.23051044106146 1 1 3.41334241390901 -2.03704258006761 0.661957748573607 15.9078353923298 20.1212379767707 0.790599237019852 0.430496292415248 -8.59397148219739 51.9519734790433 -0.165421463453435 0.868847534369804 ITGB7 other 1 1 1 0.790599237019852 -0.165421463453435 7.13269274210778e-05 298.719836514073 103.790913590334 2.87809237033147 0.00456979704842353 -591.288867228604 266.367298547646 -2.2198252955696 0.0278916918586133 GALNT6 other 0.533240109399978 1 1 2.87809237033147 -2.2198252955696 0.161355303713143 61.739999690752 36.7808847547698 1.67858930263349 0.0954470332926659 -31.2987877475917 94.9531316383485 -0.329623543821604 0.74217359884342 CSAD other 1 1 1 1.67858930263349 -0.329623543821604 3.05213811719723e-06 62.5739944592178 17.2958655586015 3.6178585134815 0.000410301096518471 -105.156633650523 47.0999353584299 -2.2326279824013 0.0271168048961146 LMBR1L other 0.0265413930671471 1 1 3.6178585134815 -2.2326279824013 7.0024583424846e-11 210.402725808954 46.0618661618749 4.56782895138328 1.08185246073468e-05 -495.26092829108 121.372307725713 -4.08051010622878 7.56552300006749e-05 C12orf10 other 8.34552985257315e-07 1 0.109537561649387 4.56782895138328 -4.08051010622878 5.60472581780536e-10 1050.36351439119 192.098124581101 5.46784887505628 2.2712045124049e-07 -1190.35240479935 523.723652493246 -2.2728635591166 0.024688222112538 ESYT1 other 6.40788302749686e-06 1 0.00258417649421429 5.46784887505628 -2.2728635591166 1.4525428271322e-07 2761.19138117767 886.481082912891 3.1147775563407 0.00220581032726029 -7678.37663113493 2256.71192214566 -3.40246203150041 0.00085638642407062 TMBIM6 other 0.0014262518019611 1 1 3.1147775563407 -3.40246203150041 4.01217713184285e-09 532.458297167207 89.1527214538765 5.97242897899283 2.01106796435783e-08 -149.497151424287 241.113789235468 -0.620027381670365 0.536300627099672 ANKRD52 other 4.37969255711965e-05 1 0.000241648693862875 5.97242897899283 -0.620027381670365 1.40514617199549e-07 160.310371664631 33.8419373847298 4.73703292580898 5.23183230374963e-06 -159.656925352671 87.3659771050579 -1.82744966224877 0.0697464909807187 ZNF740 other 0.00138196126015757 1 0.0544215196236036 4.73703292580898 -1.82744966224877 5.55844264326252e-12 222.494884910486 40.562751772503 5.48520194483728 1.75884393434786e-07 -120.557384910486 68.3191090688081 -1.76462173692965 0.0797042036640736 WDFY2 other 6.89135718911687e-08 1 0.00201510749558235 5.48520194483728 -1.76462173692965 0.00630572717671984 132.856719417871 55.238692351921 2.40513874896698 0.0174635472685849 -57.491451251781 96.7315836654434 -0.594340018774234 0.553237163965146 HNRNPA1L2 other 1 1 1 2.40513874896698 -0.594340018774234 0.00127592852443961 -121.090471836027 37.8940294213336 -3.19550266058156 0.00170419647820431 -11.2278776101984 64.2543902510599 -0.174741018727715 0.86152035202656 LPAR6 other 1 1 1 -3.19550266058156 -0.174741018727715 3.54413631780568e-10 218.653000703683 81.5984205879211 2.67962295260467 0.00817753400692876 -539.27225815099 138.034639939377 -3.90678932757627 0.000140030920023195 ESD other 4.09383186069734e-06 1 1 2.67962295260467 -3.90678932757627 1.39068589740171e-10 445.058133137155 79.3514304390807 5.60869704143308 9.81220876474124e-08 -100.443403108347 134.488373269005 -0.746855662440344 0.456343568007875 RB1 ts 1.63572475252389e-06 1 0.00114086551307646 5.60869704143308 -0.746855662440344 0.0172826311314209 7.71718972338198 6.93750451334472 1.11238698418682 0.267705254218958 -26.5869728385795 15.4151663679617 -1.72472824515452 0.0865827857937658 MORN3 other 1 1 1 1.11238698418682 -1.72472824515452 6.91943379389899e-09 449.977310753546 92.1857460562876 4.88120268049678 2.61176377304237e-06 -253.038936060421 204.83714417466 -1.23531763284427 0.218593562290938 SETD1B other 7.45084630927044e-05 1 0.0277787194900787 4.88120268049678 -1.23531763284427 3.30126798162903e-20 234.259577504995 38.2937545440033 6.11743560521882 7.52757608100972e-09 -410.684824695715 85.0258434111706 -4.83011762329381 3.26587182112587e-06 VPS33A other 4.66865317961977e-16 0.0475510937155927 9.2107420927235e-05 6.11743560521882 -4.83011762329381 0.00206692198809786 158.970969234328 62.0041272059214 2.56387721911432 0.0113904960216311 -128.416711645719 137.665764671027 -0.932815155260937 0.352498790253129 VPS37B other 1 1 1 2.56387721911432 -0.932815155260937 0.887044177691714 -18.4788666322654 161.756084261816 -0.114239082360301 0.909197074770011 -168.20908195337 359.422749942653 -0.467997871532085 0.640447761478969 RHOF other 1 1 1 -0.114239082360301 -0.467997871532085 9.34543871114636e-14 306.598025594149 67.6831267393605 4.52990339490107 1.18602186292105e-05 -617.605776965265 151.959770869468 -4.06427157287425 7.70289178451699e-05 DENR essential 1.22051429567571e-09 1 0.119622165094217 4.52990339490107 -4.06427157287425 0.000300390009183364 88.1062186127262 24.2792118726698 3.62887473756527 0.000396315830460193 4.81288815352531 42.6833498510457 0.1127579763613 0.910381684512408 DIAPH3 other 1 1 1 3.62887473756527 0.1127579763613 0.0317451893581744 105.037609598523 75.4674577675126 1.39182652636989 0.16612100540644 -193.397102172664 139.313556045551 -1.38821452601087 0.167215634852922 SLAIN1 other 1 1 1 1.39182652636989 -1.38821452601087 1.24881153088459e-15 551.155745269958 61.372919991679 8.98043869095171 1.35886146920297e-15 188.671133797312 113.294921836105 1.66530971326542 0.0980251379571707 RBM26 other 1.69288891126715e-11 1 1.90362903220644e-11 8.98043869095171 1.66530971326542 7.33514539662975e-10 329.95658452929 61.0600880412841 5.40380132282481 2.43364044554967e-07 -192.037968575337 116.542592814065 -1.64779214138232 0.101434153295927 MBNL2 other 8.33785977234904e-06 1 0.00276388545401076 5.40380132282481 -1.64779214138232 0.0387626496247777 56.418677496982 21.8931665993231 2.57699941399643 0.0109176295380363 51.1061232321456 45.0417231518658 1.13463961091881 0.258312499645982 ZIC5 other 1 1 1 2.57699941399643 1.13463961091881 3.26490736273485e-08 66.7946230354716 13.6465694409964 4.89460910482089 2.47578733767693e-06 -40.4637118463389 27.359316505108 -1.47897378352943 0.141203224492328 ABHD13 other 0.00033664459817159 1 0.0263819898702853 4.89460910482089 -1.47897378352943 0.0780506203953409 17.0823797648735 27.2686684688724 0.626447154336606 0.531949171649378 -96.5789478684244 54.5902748075979 -1.76916031671968 0.078846535206679 RAB20 other 1 1 1 0.626447154336606 -1.76916031671968 0.000912404281749648 75.054156440081 20.596197465106 3.64407830946647 0.000369191671482488 11.2645025980314 37.750631193249 0.298392430589236 0.765816613028355 GRTP1 other 1 1 1 3.64407830946647 0.298392430589236 1.03951271985147e-12 600.970013872586 79.8917347968914 7.52230522219139 4.58690157253621e-12 -10.5394055309757 146.433020989236 -0.0719742409176304 0.942718285372853 CUL4A other 1.3192455927635e-08 1 6.15975012175888e-08 7.52230522219139 -0.0719742409176304 0.217610989478747 58.6991086107974 53.9025432293356 1.08898588255946 0.277991933372193 -96.4084508617506 120.011355460836 -0.803327739208915 0.423118590035943 CDH24 other 1 1 1 1.08898588255946 -0.803327739208915 2.57443849196948e-06 14.7625954913999 2.87032885007533 5.14317218078077 8.26463308514377e-07 3.10116230022965 6.89444816897375 0.449805731252783 0.6534955655257 REM2 other 0.0225649533821125 1 0.00907291420087083 5.14317218078077 0.449805731252783 0.0326454383758444 20.2453437933946 16.1163975860328 1.25619535540251 0.211024458144019 -47.2503543154912 31.9159167445444 -1.48046364118831 0.140875219079962 CBLN3 other 1 1 1 1.25619535540251 -1.48046364118831 0.594199930980428 2.10219943211198 2.24382480026584 0.936882162931313 0.350398747132585 -0.480926764217615 5.08404159360499 -0.0945953638189257 0.924768652676442 TSSK4 other 1 1 1 0.936882162931313 -0.0945953638189257 0.183716536381004 20.9475690218435 14.7862112686395 1.41669618006012 0.158645249179439 -12.0853458031729 28.1793874498478 -0.428871842039922 0.668631780564097 NOVA1 other 1 1 1 1.41669618006012 -0.428871842039922 0.000974967954353993 103.615700466281 67.9959599727083 1.52385083625365 0.129545032524439 -276.250370340912 110.242492092517 -2.50584293857472 0.013228503870802 TMX1 other 1 1 1 1.52385083625365 -2.50584293857472 0.283938811806531 -52.5832726487442 43.7659990209413 -1.20146400916346 0.231380537992523 -103.702308190662 71.0519768350256 -1.45952741654813 0.146417969656611 FRMD6 other 1 1 1 -1.20146400916346 -1.45952741654813 0.138570031168921 108.03759588942 95.417929119342 1.13225676648562 0.259252814985328 -123.743450571717 138.982798897931 -0.890350831562933 0.374639861308709 PELI2 other 1 1 1 1.13225676648562 -0.890350831562933 0.276136378496769 11.2054206161137 18.2778525807992 0.613060017120664 0.540718119303533 41.0709913112164 25.7264045113441 1.59645283090787 0.112385890038368 RTN1 other 1 1 1 0.613060017120664 1.59645283090787 0.00697786813442781 51.6808326937834 20.6675796937454 2.50057498069904 0.0134256798306195 -15.3124008697877 28.9856922210725 -0.528274458757126 0.59805477903859 C14orf37 other 1 1 1 2.50057498069904 -0.528274458757126 1.12252394598607e-05 33.7190299776963 7.68971248311915 4.3849532803363 2.12420221386203e-05 46.163258105571 10.9317960716567 4.22284296221555 4.08557310567343e-05 SYT16 other 0.0923275945573539 0.588608517334371 0.209021497844024 4.3849532803363 4.22284296221555 0.00206979283815637 12.1216491603439 21.4299961784777 0.565639352400717 0.572441366241763 -83.4371298468672 29.8310639775352 -2.79698806283615 0.00579938942088798 SLC38A6 other 1 1 1 0.565639352400717 -2.79698806283615 8.23143126658501e-09 148.502122391227 29.3108038000893 5.06646366316214 1.13257079284686e-06 -45.8271430255867 41.0661303304572 -1.1159352648233 0.266165839653084 NAA30 other 8.82080174527249e-05 1 0.0123382262172737 5.06646366316214 -1.1159352648233 8.17311127310203e-08 26.9933594613139 4.47901251741035 6.02663184270821 1.17490781562857e-08 19.459697396118 6.52556777613519 2.98206961657567 0.00332623890241766 ADAM21 other 0.000819272674015748 1 0.000142610310660996 6.02663184270821 2.98206961657567 1.05857510052121e-06 396.606323802088 93.491783105472 4.24215166967839 3.85886334280783e-05 -105.408664604948 133.803559355457 -0.787786700986953 0.432064588278366 DCAF5 other 0.00964361916574819 1 0.368984512839285 4.24215166967839 -0.787786700986953 0.0432559730194185 94.6054702135629 49.9988404651394 1.89215328462516 0.0603975649568699 -32.1380666916449 73.1404878268921 -0.439401864090773 0.661002736457166 RAB15 other 1 1 1 1.89215328462516 -0.439401864090773 1.9079062362709e-12 74.2654613801128 14.1864116494629 5.23497154990034 5.25630853901592e-07 -50.327337763142 20.3617698725748 -2.47165831251868 0.0145232878565692 WDR89 other 2.40129078897055e-08 1 0.00584764324965521 5.23497154990034 -2.47165831251868 0.830450099119779 2.49835891067151 5.72685917041465 0.436252898199104 0.663256393476479 4.89675972800435 8.27610625599646 0.591674342563739 0.554925137819994 ESR2 other 1 1 1 0.436252898199104 0.591674342563739 0.00517569054724733 232.407169330554 86.5145449183026 2.68633637904494 0.00801185208705057 -75.6574009728974 133.91216565457 -0.564977801703677 0.572905658618579 STON2 other 1 1 1 2.68633637904494 -0.564977801703677 3.3881571992844e-08 39.7621862241644 9.3423414810822 4.25612640093289 3.58888887968846e-05 -37.7630055498853 16.141848445896 -2.3394474106518 0.0205880354578925 EFCAB11 other 0.000348878546810315 1 0.344588776943437 4.25612640093289 -2.3394474106518 0.69897634660357 -5.07335806708776 9.17244340983049 -0.553108680032894 0.580991034302121 -13.0817363708837 16.1010469449324 -0.812477375888961 0.41777195589886 GPR65 other 1 1 1 -0.553108680032894 -0.812477375888961 8.08073763780439e-07 98.5180324941977 28.9626958379587 3.40154911840352 0.000850001703527089 -81.7314007779996 43.6931184198098 -1.87057833667793 0.063264859886742 PTGR2 other 0.00742943018419736 1 1 3.40154911840352 -1.87057833667793 0.00064809205209241 110.241344085575 62.5937871039966 1.76121863184942 0.0801860471544472 -213.084071788654 93.5422910291331 -2.27794369203861 0.0241055282613663 JDP2 other 1 1 1 1.76121863184942 -2.27794369203861 0.0462931860531281 36.3759017616861 27.8089722607551 1.30806350628861 0.19281360428603 -63.3756077704155 45.8916492035456 -1.38098344405368 0.169297837255495 AK7 other 1 1 1 1.30806350628861 -1.38098344405368 0.00032387562995467 78.772809458333 23.929291832769 3.29189889984378 0.00122925812931332 -39.5291693282664 41.8763334902467 -0.943950103403228 0.346645514416804 FAM181A other 1 1 1 3.29189889984378 -0.943950103403228 0.72516914551476 84.8414367462386 142.702620318571 0.594533138612577 0.553016877061636 -67.2164023727533 249.033635521906 -0.269908931104371 0.787587031827859 FBLN5 other 1 1 1 0.594533138612577 -0.269908931104371 0.00148370369855868 1145.46818181818 335.069566466757 3.4185980956042 0.000806831214363339 114.168181818179 537.306650765778 0.212482353708938 0.832013567088812 WARS essential 1 1 1 3.4185980956042 0.212482353708938 2.50799884097333e-06 81.7366941148093 21.644403654303 3.77634308712218 0.000231565878955857 -63.8099787635565 37.2034982082298 -1.71516071973686 0.0884519446161127 WDR20 other 0.0220227378225868 1 1 3.77634308712218 -1.71516071973686 1.90529265902445e-06 111.631059527057 73.2318543299577 1.52435112490919 0.129645083908846 -411.817741951776 115.180192713606 -3.57542153949818 0.000478444547102963 NIPA2 other 0.0169361464460683 1 1 1.52435112490919 -3.57542153949818 4.58721820159694e-13 226.644401813742 39.9913143471566 5.66734065918132 7.00983218017423e-08 -124.767933961167 58.0967645705758 -2.14758833617317 0.0333212370905853 SLC12A6 other 5.88494223082872e-09 1 0.000820948213650489 5.66734065918132 -2.14758833617317 0.12695232118459 13.0294157351909 11.4926796360334 1.13371434233138 0.258923644248187 -17.2844814784816 18.2733329177513 -0.945885545689963 0.345896896435195 DUOXA1 other 1 1 1 1.13371434233138 -0.945885545689963 2.29387595624023e-11 137.85969926294 27.5075615280756 5.01170193229355 1.61407206802372e-06 -114.968645127157 48.0445926659891 -2.39295701654566 0.0180493193587791 MFAP1 essential 2.78453602328002e-07 1 0.0174109953977719 5.01170193229355 -2.39295701654566 2.31479615804197e-07 565.206258760437 102.830111588091 5.49650535267819 1.58517261772985e-07 106.875816273433 157.492337377725 0.678609626683645 0.498410389924135 TCF12 other 0.00223285237404728 1 0.00182215592408046 5.49650535267819 0.678609626683645 0.000127149185576353 260.293403528658 111.761560772846 2.32900651824022 0.021269389515567 -372.830863074377 173.74745496493 -2.14582057129776 0.0335874593699992 SORD other 0.919924357644912 1 1 2.32900651824022 -2.14582057129776 0.000125983868397863 616.814824232404 961.061666986009 0.641805667025302 0.522064010918574 -5690.02566588266 1686.49862361944 -3.37386914296506 0.000962396283343775 SERF2 other 0.912375174937322 1 1 0.641805667025302 -3.37386914296506 1.08636455452499e-12 154.162344047692 23.0882163668434 6.67710062995952 5.5873850513715e-10 -25.7928523139329 37.6150888324874 -0.685704942205431 0.494057901336185 ZSCAN29 other 1.37772752804859e-08 1 7.10994747787023e-06 6.67710062995952 -0.685704942205431 0.000304367325148 26.2682380258113 7.91322217019274 3.31953753614522 0.00115951466219546 -7.24972325719532 12.5820041754832 -0.576197810466622 0.565440865786845 DUOX2 other 1 1 1 3.31953753614522 -0.576197810466622 0.043951753568438 9.21266651086698 22.3462068673418 0.412269812302283 0.68071873777256 -67.9182559923591 33.3162841431277 -2.03859036921946 0.0432126755990159 LYSMD2 other 1 1 1 0.412269812302283 -2.03859036921946 0.803930339179931 2.82929104477612 12.4901908059625 0.226521042690997 0.821098548457057 -8.39113958062949 18.7260916701496 -0.448098820001261 0.654715758737357 SLC27A2 other 1 1 1 0.226521042690997 -0.448098820001261 0.887044235656754 -4.25272882589289 17.3359883719575 -0.245312164189729 0.80654562901166 6.60749201126348 26.0258021436157 0.253882357777178 0.799929546315019 FGF7 other 1 1 1 -0.245312164189729 0.253882357777178 0.819039009455933 1.17583147339846 18.2879627719665 0.0642953776787477 0.948819512961629 -15.8627840752915 29.2668925709024 -0.542004383856678 0.588609160591367 GCNT3 other 1 1 1 0.0642953776787477 -0.542004383856678 8.66482161434675e-10 324.642439236475 50.3273708403352 6.45061392669232 1.40584505202366e-09 31.4039050206465 80.0836586996904 0.392138740044452 0.695504989502751 BNIP2 other 9.81497620261484e-06 1 1.76560080083651e-05 6.45061392669232 0.392138740044452 0.00598702761538373 129.588050971381 70.3757250306818 1.84137429369124 0.067515966686913 -185.347190307082 112.62483469343 -1.645704438205 0.101890885521692 GTF2A2 essential 1 1 1 1.84137429369124 -1.645704438205 5.13389147007341e-09 725.54447843907 318.486351222958 2.27810226608785 0.0240958459484705 -1850.42341973099 450.740408044552 -4.10529738782172 6.53107556792668e-05 SRP14 essential 5.57078563417666e-05 0.938450248355385 1 2.27810226608785 -4.10529738782172 3.29632410475297e-08 332.306598522265 64.0744854668667 5.18625465504678 6.74973622682607e-07 -12.567187504714 91.7717109589397 -0.13693966662926 0.891259701133356 BAHD1 other 0.000339719162235841 1 0.00745170879441598 5.18625465504678 -0.13693966662926 0.5655379319179 0.803248047848474 10.0293993602521 0.0800893472276968 0.936273664257595 13.6603671706263 14.4181700118293 0.947441121821894 0.344948086151487 DISP2 other 1 1 1 0.0800893472276968 0.947441121821894 1.66639184147047e-10 296.166266085148 49.0929574610349 6.03276480786914 1.40066849754086e-08 -26.911982338406 75.4566714362676 -0.356654777187415 0.721895005896833 CDAN1 essential 1.9526779598351e-06 1 0.000169382841407616 6.03276480786914 -0.356654777187415 0.00094116038396616 345.950057476215 94.405554058768 3.66450958235846 0.000341108853818619 77.6817540167828 164.208986416737 0.473066399786662 0.636840011401101 TLE3 other 1 1 1 3.66450958235846 0.473066399786662 2.63391485127671e-08 737.268868838929 144.625113750145 5.09779283639933 9.95337121028669e-07 -356.807143767065 244.151656690888 -1.46141602560906 0.14593875366783 ANP32A other 0.000273426700711036 1 0.0108790347328433 5.09779283639933 -1.46141602560906 0.000987517842492576 192.643069022996 76.4284409616296 2.52056782264748 0.0127914429050104 -198.549782230746 129.326245773309 -1.53526286210129 0.126883517040171 COMMD4 other 1 1 1 2.52056782264748 -1.53526286210129 5.13731256941729e-06 364.535833958387 78.4023134653099 4.64955455835727 7.20413365579477e-06 -0.580344622358516 134.392392100407 -0.00431828478746721 0.996560217697295 UBE2Q2 other 0.0436466075897693 1 0.0740008609123239 4.64955455835727 -0.00431828478746721 0.184357128319048 15.9313977651441 8.61649579513761 1.84894162823527 0.066408787557189 12.6678768868849 15.0562488923198 0.84137005023521 0.401462378823837 PSTPIP1 other 1 1 1 1.84894162823527 0.84137005023521 3.23085863993412e-05 240.449543846204 76.1591915305947 3.1571966431604 0.00192370557074885 -236.874044074485 130.547371344576 -1.81446812474885 0.0715905909181689 ETFA other 0.252136208260459 1 1 3.1571966431604 -1.81446812474885 0.408775193961698 -5.1618657562151 8.81946862211153 -0.585280811961124 0.559215547126217 14.0022952559928 15.6473363375388 0.894867660152519 0.372254335987642 BCL2A1 other 1 1 1 -0.585280811961124 0.894867660152519 1.82840807716636e-10 272.33411377527 43.4542748487422 6.26714206423244 3.65705051745498e-09 -54.1137940761636 76.9580640072394 -0.703159503480664 0.483039081679297 HMG20A other 2.13960313190008e-06 1 4.52779424566101e-05 6.26714206423244 -0.703159503480664 8.20361238878416e-10 86.7069447498193 16.5951244630126 5.22484449833883 5.65865846684764e-07 -54.2102820617521 28.83142753368 -1.88024966847116 0.0619873955810499 SCAPER other 9.3004353651646e-06 1 0.00627997916650751 5.22484449833883 -1.88024966847116 1.24215809069025e-05 1784.77106159988 601.610698792801 2.96665445807599 0.00349780742766583 -2337.72218814487 1054.15317130593 -2.21763046564552 0.0280637008149895 TSPAN3 other 0.10162095339937 1 1 2.96665445807599 -2.21763046564552 0.000123466946247758 143.709409412228 52.08588757814 2.75908535102975 0.00650875415222314 -190.225262624271 93.5808169580866 -2.03273778545309 0.0438196226594816 WDR61 essential 0.895505761134987 1 1 2.75908535102975 -2.03273778545309 9.87028023573846e-07 321.564064423471 65.3502952278799 4.92062144940831 2.2458653841718e-06 -29.312115305704 218.084280079627 -0.134407281877454 0.893260698903525 NCOA2 other 0.00900959179918207 1 0.0239970716298757 4.92062144940831 -0.134407281877454 5.30235567423726e-07 118.828727312357 38.6627799712445 3.07346567941406 0.00252842820328727 -197.222648817768 65.56108938211 -3.00822714626193 0.0030990709026515 NEIL1 other 0.00495133972860275 1 1 3.07346567941406 -3.00822714626193 0.014148771251682 151.630373353611 72.5048631305933 2.09131314516792 0.0381634276202418 -143.732909003858 130.266846562154 -1.10337290567082 0.271609037743815 DNAJA4 other 1 1 1 2.09131314516792 -1.10337290567082 0.122350111196842 343.374269970634 267.092560941536 1.28560027565049 0.200537797429236 -388.481116573729 437.649909400908 -0.887652683638195 0.376130024135217 TPM1 other 1 1 1 1.28560027565049 -0.887652683638195 2.90681476381552e-09 1211.97247856989 197.428561447861 6.13878999918642 6.75800622990269e-09 -250.901600366954 394.892617266138 -0.635366652595226 0.526132272554031 IGF1R other 3.20243782529556e-05 1 8.29072204284462e-05 6.13878999918642 -0.635366652595226 0.625615207930602 15.6437607529602 26.4834068858566 0.590700464648857 0.555581456349014 -29.1742190399083 52.4133635542883 -0.556617951253794 0.578591237890834 ARRDC4 other 1 1 1 0.590700464648857 -0.556617951253794 0.0641588864068847 45.5728785211604 19.2731825269855 2.36457463407256 0.0192893345892517 30.2330027760701 31.7875843381483 0.951094693275811 0.343037007269698 PIF1 other 1 1 1 2.36457463407256 0.951094693275811 3.45135306865275e-10 250.448631803453 39.888143576558 6.27877382467706 3.31551307575471e-09 -17.9506703800716 65.3675131018403 -0.27461149320619 0.783982780704327 USP3 other 3.99010928266945e-06 1 4.10924690609039e-05 6.27877382467706 -0.27461149320619 0.0589088529214027 24.4615403705128 21.9624266448077 1.11379041879673 0.267186946677281 -57.9763166275804 38.4989277082612 -1.50592029645386 0.134233447549784 CYP11A1 other 1 1 1 1.11379041879673 -1.50592029645386 5.8982197773983e-05 68.4664501834322 18.6697432316167 3.66724112560296 0.000339139101035318 -35.7434559266577 32.3888259488706 -1.10357368257444 0.27153370144924 BBS4 other 0.445197628798024 1 1 3.66724112560296 -1.10357368257444 1.62873974008212e-05 810.393249307746 329.458826358919 2.45977094699198 0.0150384557587364 -1665.41099334797 574.415897902719 -2.89931215244676 0.0043017817525446 PML other 0.131553308806433 1 1 2.45977094699198 -2.89931215244676 0.00684147427566266 25.6709395100789 9.25395211835233 2.77405147355027 0.00621239951348981 -11.7995775917435 18.4006917909823 -0.641257281290162 0.522296536432525 ADAMTS17 other 1 1 1 2.77405147355027 -0.641257281290162 3.95386727095498e-10 69.610587920739 12.268827711049 5.67377662806769 6.61526816070326e-08 -52.9876584601936 24.1911625414091 -2.19037255317896 0.0299815279917756 LINS1 other 4.5576228032298e-06 1 0.000776037107932099 5.67377662806769 -2.19037255317896 7.28298517307779e-08 753.21555149981 135.785801045807 5.54708626158721 1.35102966484401e-07 21.1456683641932 226.039523710434 0.0935485441531971 0.925597819738926 ULK3 other 0.000733250947225472 1 0.00155868292433054 5.54708626158721 0.0935485441531971 0.435183395830423 47.890948757168 47.5951501195739 1.00621489031658 0.315911337964566 -43.0092530621306 88.0824604832011 -0.488283965118494 0.626052380892109 PCSK6 other 1 1 1 1.00621489031658 -0.488283965118494 0.0888298245582113 29.1254182840316 22.1387018236035 1.31558835364859 0.190360408444151 -43.75940302503 38.6886173696167 -1.13106660305197 0.259868965369607 CCDC33 other 1 1 1 1.31558835364859 -1.13106660305197 8.51524111158454e-06 83.7919627253322 18.8409923770867 4.44732214993278 1.69709048698094e-05 -17.2596769609416 32.7834471834888 -0.526475353990056 0.599346089697475 CELF6 other 0.0708382908072717 1 0.168555027166947 4.44732214993278 -0.526475353990056 1.1250252039515e-07 761.623149156635 170.08558059845 4.47788193729796 1.52307113032223e-05 -484.297646031418 283.137583844401 -1.71046753827484 0.0893329906705607 SCAMP2 other 0.00111444996703436 1 0.151911114538339 4.47788193729796 -1.71046753827484 0.912387866495566 3.55292776403243 10.5116908871324 0.337997740057373 0.735837471440943 6.82669512767026 17.9978481684996 0.379306185037084 0.704996927878684 CYP1A2 other 1 1 1 0.337997740057373 0.379306185037084 0.230399026517947 185.302842973019 109.345103542465 1.69466063838016 0.0921479922767942 159.192376945554 191.105159223754 0.833009310644329 0.406121209161745 HAPLN3 other 1 1 1 1.69466063838016 0.833009310644329 0.00405506916902709 22.679004173359 6.80406080300837 3.33315718803272 0.0010739787999934 20.582233990363 12.2313174130592 1.68274874204373 0.0944370147793556 RHCG other 1 1 1 3.33315718803272 1.68274874204373 3.65946750553267e-14 453.070340946708 56.2192379322705 8.05899114983628 2.10385051319261e-13 -46.4448306300337 98.867773330481 -0.469767135088444 0.639194634340818 POLG other 4.8283014267998e-10 1 2.8814336628686e-09 8.05899114983628 -0.469767135088444 1.99134424142056e-06 350.999668811086 67.3742236372764 5.20970261120586 6.06460179144938e-07 65.4597632177318 120.022994183964 0.545393519490099 0.586282331790725 FANCI other 0.0176691974541246 1 0.00672200462564249 5.20970261120586 0.545393519490099 0.0558280009422389 205.824500416027 90.3676965798725 2.27763358153216 0.0241244730259439 -7.68682748311245 158.169512697624 -0.0485986670377339 0.961302103073739 ABHD2 other 1 1 1 2.27763358153216 -0.0485986670377339 0.00163970357258012 22.1403694864315 8.56587688714312 2.58471721904653 0.0106740750379643 -24.1162847530951 15.4404483711052 -1.56189018436963 0.120366511424662 WDR93 other 1 1 1 2.58471721904653 -1.56189018436963 7.93048878810316e-08 180.465441484585 30.7813208850119 5.86282317639128 2.67853228765449e-08 38.8780707230511 55.6305074554982 0.698862413832046 0.485692115917577 TICRR other 0.000795269415670985 1 0.000320004252406083 5.86282317639128 0.698862413832046 0.052633071398551 27.9776648881824 12.8866371094624 2.17106019596369 0.0314680154115773 -9.08445907594509 22.7206119508998 -0.399833380173782 0.689836883208572 NTRK3 other 1 1 1 2.17106019596369 -0.399833380173782 3.02147501249387e-11 92.7849729564064 13.4235674207064 6.91209497806685 1.16994227309896e-10 -14.7415151377952 23.4607029137673 -0.628349252449063 0.530699955452695 DET1 other 3.65054611009509e-07 1 1.52080796080133e-06 6.91209497806685 -0.628349252449063 0.000617687112482677 3655.52368099356 995.770454889959 3.67105055491683 0.000331880967073432 -289.473640767739 1740.33281022183 -0.166332346932448 0.868112186597684 MFGE8 other 1 1 1 3.67105055491683 -0.166332346932448 0.00012217183069872 177.456224572007 45.3562529820056 3.91249745966472 0.000136383059887477 -46.2359416840225 83.1355076776915 -0.55615155275499 0.578909225027252 ZNF710 other 0.886586532529255 1 1 3.91249745966472 -0.55615155275499 5.10526149248812e-16 600.232515455144 71.1204619611465 8.43965996428784 3.08827569545822e-14 -162.568240407799 128.672608257267 -1.26342539107284 0.208478020814227 UNC45A essential 6.96102404500756e-12 1 4.26923232140144e-10 8.43965996428784 -1.26342539107284 0.0340191854864312 66.3659865753972 26.1844505667265 2.53455715659472 0.0122705796596282 72.0252209742805 51.6700272231061 1.39394586852611 0.165368435814347 ST8SIA2 other 1 1 1 2.53455715659472 1.39394586852611 0.0326301448558821 31.0703083161196 20.8048272232811 1.49341823331035 0.137387100056843 -68.2952999299683 41.4506600139377 -1.64762876892682 0.10148106094278 MCTP2 other 1 1 1 1.49341823331035 -1.64762876892682 1.04409005809551e-05 868.453 222.546789509077 3.90233892798789 0.000143842184857698 -667.554474509805 406.742975281979 -1.64121943113342 0.102861039960427 FURIN other 0.0861583115940417 1 1 3.90233892798789 -1.64121943113342 0.00373650616044437 897.992214614014 417.75387340186 2.14957244394042 0.0331610127458122 -1353.53356230113 761.638122144192 -1.77713473491927 0.0775329590824839 IQGAP1 other 1 1 1 2.14957244394042 -1.77713473491927 2.63048486150997e-07 343.978801238157 62.6011462072697 5.49476842004231 1.59825310684687e-07 12.2756199808073 114.132800381036 0.107555583844651 0.914489142229913 CRTC3 other 0.00252368717613266 1 0.00183623299445637 5.49476842004231 0.107555583844651 1.47862598147231e-09 157.362795250958 26.4265338409559 5.95472702542158 1.73706091275502e-08 -40.8432970947823 46.8145330908317 -0.872449096427732 0.384339511724228 EFL1 other 1.65428674807123e-05 1 0.000209211616332214 5.95472702542158 -0.872449096427732 0.56495478509821 3.17525258675588 5.25842633365915 0.603840842350707 0.546849588376935 -5.28460403619763 8.79370232915734 -0.600953254771365 0.548766217499846 SH3GL3 other 1 1 1 0.603840842350707 -0.600953254771365 2.16966614505255e-07 485.887420109469 127.559761656817 3.80909633099416 0.000201506465757502 -586.423691250377 223.702574875278 -2.62144363594084 0.00963988697994528 SEC11A other 0.00209893502872384 1 1 3.80909633099416 -2.62144363594084 2.12291580431995e-31 1177.29501307708 77.9801000486198 15.0973775661104 3.4992771593538e-32 467.668393135268 246.170174672297 1.89977682616438 0.0593317057472053 GLYR1 other 3.08077541522911e-27 1 5.08514956797294e-28 15.0973775661104 1.89977682616438 1.13387224108412e-09 261.657286453474 41.0732236220772 6.37050767821473 2.09719922333303e-09 95.8007040461448 93.6884419054305 1.02254560005221 0.308136809224529 PMM2 other 1.27639998178839e-05 1 2.61982126978762e-05 6.37050767821473 1.02254560005221 4.93178501962282e-11 334.393824512396 75.5018313767236 4.42894984684419 1.82977323427725e-05 -539.571204336477 156.197392549649 -3.45441876800196 0.000719621060913204 SLC5A2 other 5.90975798901402e-07 1 0.181129252461105 4.42894984684419 -3.45441876800196 0.0518747387398016 -68.3907827359184 29.8630856009337 -2.29014455002534 0.0234069629660862 -13.1647403072423 61.8727023546063 -0.212771380693738 0.831794171524534 ITGAX other 1 1 1 -2.29014455002534 -0.212771380693738 0.655002957121206 79.9882276649875 87.3614701381977 0.915600750976988 0.36136575733853 89.5297450990174 180.732488153887 0.495371618094396 0.621072533150974 TGFB1I1 other 1 1 1 0.915600750976988 0.495371618094396 5.02308105328728e-11 551.497530802614 117.248938199623 4.70364626981658 5.80881896050709e-06 -761.461345837283 242.56336690188 -3.13922648569313 0.00204520221631526 C16orf58 other 6.0166464856275e-07 1 0.0602025997066955 4.70364626981658 -3.13922648569313 7.00654201569546e-09 119.513775056779 21.4010266481287 5.58448793236886 1.08083321214074e-07 -26.1429314374115 44.2496262036015 -0.590805701208018 0.555545724598875 ARMC5 other 7.54184182569459e-05 1 0.00125322610947719 5.58448793236886 -0.590805701208018 4.46089332833531e-21 372.939866894399 37.8778853154083 9.84584708963916 4.33389902031815e-18 45.6101066022731 86.1589837586157 0.529371455100434 0.597300298932295 PARN other 6.33982159823015e-17 1 6.16237101699038e-14 9.84584708963916 0.529371455100434 4.10233020934015e-09 265.441377184872 58.3402405781502 4.54988485742182 1.09583184760066e-05 -26.8194866376084 88.7708329130508 -0.302120479863893 0.762975948609833 FTO other 4.47400132630636e-05 1 0.110898182977187 4.54988485742182 -0.302120479863893 4.6465402440723e-06 191.416929935929 186.508789594197 1.02631586614449 0.306352081382557 -1434.95908746445 378.948278181719 -3.78668850099996 0.000218362498681535 UQCRC2 essential 0.0396117555807164 1 1 1.02631586614449 -3.78668850099996 0.723306264891751 -12.4822699223479 15.9644422548272 -0.781879487119169 0.43548587031766 -18.5749308610628 32.436529762276 -0.572654688932401 0.567713641794815 IGSF6 other 1 1 1 -0.781879487119169 -0.572654688932401 1.49018930466827e-05 159.835661345496 58.0664914441093 2.75263163608469 0.0066225101606527 -231.419541049031 116.400773930118 -1.9881271681919 0.0485700326858169 ARHGAP17 other 0.12079474503641 1 1 2.75263163608469 -1.9881271681919 0.00237474595004389 34.2899050519527 11.5160984499461 2.97756268765775 0.0034174033647033 10.9723217484772 17.1769929991274 0.638780125778396 0.523994960357738 MYLK3 other 1 1 1 2.97756268765775 0.638780125778396 0.000102993786042573 126.526855137607 35.5530492334001 3.5588186629782 0.000500138469580239 28.724122703257 52.7349408874419 0.544688629964829 0.586781976735575 NKD1 other 0.754223495189759 1 1 3.5588186629782 0.544688629964829 1.49130219178119e-18 548.049694072239 66.6458764448847 8.22330987762564 7.46002778117662e-14 116.666513154528 105.583016218766 1.10497424048578 0.270883019173212 DHX38 other 2.08812132893203e-14 1 1.02702202463459e-09 8.22330987762564 1.10497424048578 0.00588432791405501 77.6453869602405 65.0059833185771 1.19443446582018 0.234132666436738 -139.833856005614 102.985033090805 -1.35780755522328 0.176498139960622 TXNL4B other 1 1 1 1.19443446582018 -1.35780755522328 1.4766197153814e-06 116.329766003641 40.7875476569094 2.85209022572689 0.00493601784231536 -86.6660672383165 64.6172356866601 -1.34122214169877 0.181810314068538 MARVELD3 other 0.0132674281427018 1 1 2.85209022572689 -1.34122214169877 0.301310635881866 16.017709343077 26.5566197494976 0.603153168368877 0.547294065211549 -25.9926552829759 42.2767695732172 -0.614821225589632 0.539580162482106 CHST4 other 1 1 1 0.603153168368877 -0.614821225589632 1.16416041964592e-17 1542.12617360114 169.531726358904 9.09638689301384 4.469781301944e-16 823.322461554604 268.330184012354 3.06831847704728 0.00254417962278082 ZFHX3 other 1.61748448705605e-13 1 6.28227761988229e-12 9.09638689301384 3.06831847704728 6.03176071495008e-13 724.621300923232 93.3798015653671 7.7599361829441 1.06815299102414e-12 479.365321511484 157.782632866945 3.03813742235955 0.00279427411939735 CLEC18B other 7.70901817443275e-09 1 1.44959042411887e-08 7.7599361829441 3.03813742235955 6.35651056250878e-06 662.545124629272 206.086791681138 3.21488397788431 0.00159814375598176 -181.679575782782 331.164980518083 -0.548607450880095 0.584090498249857 CPNE2 other 0.0534709668518239 1 1 3.21488397788431 -0.548607450880095 0.0472450937136065 -72.7959166455746 83.580500142162 -0.870967708039029 0.385172907109807 -304.814312129137 133.717009923617 -2.27954777259269 0.0240542274529012 NLRC5 other 1 1 1 -0.870967708039029 -2.27954777259269 1.76219971046744e-07 143.216466739367 53.4857088114903 2.67765857313646 0.00825142790552037 -165.089422028353 82.1143534038988 -2.01048190949422 0.0461967206176744 KATNB1 essential 0.00171884959758994 1 1 2.67765857313646 -2.01048190949422 0.0455219066474867 80.5909526806321 49.6565595106146 1.62296690457189 0.106724639450168 -22.2222496928286 76.5187611504886 -0.290415701439864 0.771904765928035 KIFC3 other 1 1 1 1.62296690457189 -0.290415701439864 0.410539236839105 20.890988839865 15.6406371768007 1.33568655827219 0.183609716728949 23.0253412924994 28.1647060530677 0.817524644110085 0.414883557451801 ADAMTS18 other 1 1 1 1.33568655827219 0.817524644110085 0.0065796641820929 1.63533036830324 5.54637198914089 0.294846860525226 0.768507969255199 -23.2573907735241 10.0963536188794 -2.30354360113086 0.0225858633239156 NUDT7 other 1 1 1 0.294846860525226 -2.30354360113086 6.81174808973049e-17 173.459774327322 22.4702570050256 7.71952783132505 1.3432725537966e-12 13.1665830841931 41.3981034874706 0.318047977443655 0.750876641092648 GCSH other 9.38999474169348e-13 1 1.8201343103944e-08 7.71952783132505 0.318047977443655 0.570984792074184 56.0705337274075 101.78343688114 0.550880727213853 0.582569102281588 -39.2841628468096 158.177301223654 -0.248355247832076 0.804213384720677 CMTM3 other 1 1 1 0.550880727213853 -0.248355247832076 0.57983463488425 -226.563304621261 273.069243129911 -0.829691773501839 0.408058401575225 -66.7011690518227 435.627222630168 -0.15311524529873 0.87851737263627 CDH11 other 1 1 1 -0.829691773501839 -0.15311524529873 4.18588134418134e-05 46.8555729450167 37.8425615269237 1.23817128266226 0.217770107366442 -141.544989566325 59.9751737767096 -2.36005968224959 0.0196827861424601 NOL3 other 0.321386240220491 1 1 1.23817128266226 -2.36005968224959 4.70827205166811e-09 377.134100653837 87.5927153309925 4.30554183905289 2.97358592349506e-05 -174.487400464381 151.779383632558 -1.149611997943 0.252109338832706 MAP1LC3B other 5.12071668339424e-05 1 0.288170211845906 4.30554183905289 -1.149611997943 9.22005109014205e-29 1316.10501365901 110.297948286329 11.9322710359258 1.07694223602753e-23 355.314880282822 204.264408614669 1.73948502674835 0.0839346209731943 MBTPS1 essential 1.33460239529806e-24 1 1.55348917546971e-19 11.9322710359258 1.73948502674835 0.608889690000915 -5.46470084096621 30.055597709634 -0.181819736002607 0.855961756112149 35.4437326827654 55.660952783831 0.63677912270775 0.525208049608812 CDH13 other 1 1 1 -0.181819736002607 0.63677912270775 7.08037892584019e-11 353.868990470222 63.03481780899 5.61386552337672 9.1449411902785e-08 -18.981025911312 109.225815848797 -0.173777835979616 0.862271284224587 ZCCHC14 other 8.43556345224601e-07 1 0.00106483695219603 5.61386552337672 -0.173777835979616 4.65677421217152e-05 90.200530427235 21.9529986714943 4.10880225417037 6.42372611658304e-05 40.8631594174944 40.4451320098192 1.01033566678862 0.313909086886005 TLDC1 other 0.355777549809904 1 0.600297205594685 4.10880225417037 1.01033566678862 0.127171655296555 7.71838341635866 8.78557346311915 0.878529267185525 0.381016402719699 -13.9060450235928 16.2702932889205 -0.854689265685353 0.394042296592766 OSGIN1 other 1 1 1 0.878529267185525 -0.854689265685353 0.0666873124359177 -44.2441819229575 21.6511847758154 -2.04349934569765 0.0427185019320285 -14.3062081652555 37.2815547357218 -0.383734215664235 0.701708171341618 IRF8 other 1 1 1 -2.04349934569765 -0.383734215664235 0.000285410124865349 148.565763186777 79.5428069806785 1.86774604550811 0.0640318399623689 -340.965754082856 170.758364695436 -1.99677336270467 0.0479223417093651 RHOT2 other 1 1 1 1.86774604550811 -1.99677336270467 3.5806223421939e-13 87.7408047066423 12.2803006030601 7.14484177079333 3.43537541057094e-11 7.80763425233621 25.3313513874305 0.308220202425141 0.758334008780578 ZSCAN32 other 4.60611258099823e-09 1 4.53194724162518e-07 7.14484177079333 0.308220202425141 9.66478849824217e-05 9427.98315063192 2592.07029527866 3.63724053618629 0.000389175137360098 -1022.41650116067 5480.4776275283 -0.186556094312857 0.852284662355198 RPS2 essential 0.710072010965852 1 1 3.63724053618629 -0.186556094312857 0.00218500419250457 211.793945060614 119.679099273151 1.76968197744556 0.0790048410842214 -419.925103172556 253.040446952358 -1.65951771042998 0.0992989499857318 NDUFB10 essential 1 1 1 1.76968197744556 -1.65951771042998 2.10290738925421e-11 306.986787033238 47.9675772743846 6.39988101290188 1.93391851328835e-09 -20.77205329403 102.90396319136 -0.201858632552397 0.840304435478325 PDPK1 other 2.55587364089956e-07 1 2.4191386682724e-05 6.39988101290188 -0.201858632552397 9.69525446665934e-07 69.0106682970062 13.2535922551899 5.2069406518812 6.14164444158817e-07 32.1677274931792 28.1156876429249 1.1441202470918 0.25437231669512 TIGD7 other 0.00885855400618664 1 0.00680432787683553 5.2069406518812 1.1441202470918 2.03629349338265e-13 272.825098677643 42.0289047338088 6.49136827156425 1.49509674781135e-09 -34.0698960237134 74.3039096815691 -0.458520906500352 0.647315540204223 DEF8 other 2.63577829783451e-09 1 1.87664543785281e-05 6.49136827156425 -0.458520906500352 1.80689677487683e-07 496.294892568076 107.44294176206 4.61914840034029 8.88619249192801e-06 -20.2499731228209 189.950956161563 -0.106606323716514 0.915259557569476 TCF25 other 0.00176064021743998 1 0.0906391634176657 4.61914840034029 -0.106606323716514 0.00225768593247651 279.698577501636 106.32977430491 2.63048218930265 0.0094672826492354 -59.949504033137 185.365328541938 -0.323412714258339 0.746858498524743 GALNS other 1 1 1 2.63048218930265 -0.323412714258339 2.17319421059193e-13 148.722533789468 26.8513159203942 5.53874283965761 1.53607103754387e-07 -77.6746797311262 47.0304806164599 -1.6515816702911 0.100944097760604 GAS8 other 2.81102671140066e-09 1 0.00176771055000549 5.53874283965761 -1.6515816702911 0.000333128135154345 56.4435398555725 13.7632928807752 4.1010200352863 6.64082055833477e-05 28.4543029299483 42.9853124539634 0.661954079324709 0.50898996915314 MED9 other 1 1 0.61912370065355 4.1010200352863 0.661954079324709 1.2800757261835e-14 868.287253141831 98.958691525041 8.77423943021837 2.93377318739786e-15 -11.9313049229942 402.305874889364 -0.0296572972648619 0.976378520778339 NCOR1 other 1.70365278397761e-10 1 4.09965465206977e-11 8.77423943021837 -0.0296572972648619 1.91186241740083e-07 291.537071811491 51.6998400930651 5.63903237005557 7.89244237824515e-08 -50.960399188298 161.77108549482 -0.315015498798329 0.753173569248874 COPS3 essential 0.00185928620092231 1 0.000921916194202816 5.63903237005557 -0.315015498798329 2.6385361876178e-11 98.5068906115419 12.9785143434734 7.58999743765579 3.39326651349833e-12 52.6126349963555 40.0266483021886 1.31444018492747 0.190745314335488 GID4 other 3.19605888406145e-07 1 4.5669974005174e-08 7.58999743765579 1.31444018492747 6.63233383870388e-10 32.3191162075234 4.64719321396747 6.95454540396254 9.30400840120533e-11 15.1005278981961 15.654619047608 0.964605261378333 0.33624510809373 ZNF287 other 7.55290177551597e-06 1 1.21352181576921e-06 6.95454540396254 0.964605261378333 0.73883608291028 5.6751237287214 7.61907805468677 0.744857013931026 0.457493362212898 11.6465981399907 34.4658307044785 0.337917232863253 0.735885757997729 MYOCD other 1 1 1 0.744857013931026 0.337917232863253 7.89979767422137e-11 142.572529722263 19.1046262050113 7.46272280819949 9.892255127708e-12 71.3178185585317 122.165630526565 0.583779727990057 0.560357268907997 KSR1 other 9.39127947511436e-07 1 1.3185386859722e-07 7.46272280819949 0.583779727990057 2.97119651636977e-21 451.285560106944 60.9780326937488 7.40078910668445 8.78594867873435e-12 -111.757552715707 98.2442360187738 -1.1375481885202 0.257111000777794 UTP4 other 4.22682416418764e-17 1 1.17222127271674e-07 7.40078910668445 -1.1375481885202 1.19227177509526e-10 205.669943077545 51.7981793595027 3.97060177830003 0.000113130282624415 -128.44358041204 82.6660854543927 -1.55376391304876 0.122451142049108 RANBP10 other 1.40711914896743e-06 1 1 3.97060177830003 -1.55376391304876 2.5293214951852e-14 45.4219156589621 8.52011465387956 5.3311390168065 3.63143313306159e-07 -16.5303076687586 13.5890844339872 -1.21644013245036 0.225780220652109 CTRL other 3.34815985006853e-10 1 0.00407991512499469 5.3311390168065 -1.21644013245036 0.030538848542102 -309.411380597016 296.222332641701 -1.04452415129439 0.297957567951177 -1173.25074626866 472.175053173862 -2.4847791902226 0.0140844892760034 DPEP3 other 1 1 1 -1.04452415129439 -2.4847791902226 1.25563272314303e-16 149.666428193723 26.7381000314506 5.59749675622719 1.0753057505339e-07 -72.9360685143139 42.6720415547288 -1.70922378815108 0.0895787620179075 GFOD2 other 1.72473710850926e-12 1 0.00124692454831911 5.59749675622719 -1.70922378815108 3.89314644183635e-09 276.371589376701 97.1807372803146 2.8438927004589 0.00507466402308191 -372.398539255981 156.418314467523 -2.38078603853836 0.0185228616844255 NOB1 essential 4.25326248770621e-05 1 1 2.8438927004589 -2.38078603853836 2.85498427834014e-14 176.452990046886 21.5607870817746 8.18397720721626 9.09961892632174e-14 -9.61380274738829 60.4796656387337 -0.158959257559638 0.873906578880773 PRPSAP2 other 3.77400371753784e-10 1 1.25156158712629e-09 8.18397720721626 -0.158959257559638 0.0263114727835882 105.72595192164 38.9257709690379 2.71609140396309 0.0073416638363776 50.0235622406177 151.291653600864 0.330643238077028 0.741352033252132 PCTP other 1 1 1 2.71609140396309 0.330643238077028 2.70670606844372e-15 321.856583546296 41.4547909614876 7.76403827112065 9.68854824639621e-13 -745.617935776879 161.121121511768 -4.62768586005913 7.66175820277971e-06 TOM1L1 other 3.64755709783476e-11 0.1113559937192 1.31618927927293e-08 7.76403827112065 -4.62768586005913 9.64197420864498e-12 173.310850970359 22.6263927173459 7.65967660578501 1.83984402379385e-12 112.849988371192 92.9268721935345 1.21439563935999 0.226431776148928 C17orf80 other 1.18634850663168e-07 1 2.48857302658357e-08 7.65967660578501 1.21439563935999 4.87517512849642e-06 417.646281516665 94.54704587863 4.4173382429399 1.8466646683062e-05 -892.280301565825 373.583424232735 -2.38843654104405 0.0181004039238735 TOB1 other 0.0414828651683761 1 0.182727468928899 4.4173382429399 -2.38843654104405 3.09028464225496e-11 350.734665054621 47.8960952020058 7.32282378292777 2.0306416969125e-11 -69.0897788429705 193.912408047935 -0.356293749010076 0.722180951934124 VPS53 other 3.73120967705864e-07 1 2.69120944091814e-07 7.32282378292777 -0.356293749010076 8.79319048201679e-09 344.378530738191 56.4189044999288 6.10395635630653 8.44718776134047e-09 -203.919040272175 258.012922894365 -0.790344289675998 0.430574451651986 SGSM2 other 9.40783449670976e-05 1 0.000103140162565967 6.10395635630653 -0.790344289675998 1.3009207911476e-11 684.482874085559 89.4345908244869 7.65344670082786 1.90583003595193e-12 -98.6401702281994 369.766177008564 -0.266763637026528 0.790003455190845 NPEPPS other 1.59258723252289e-07 1 2.5768727916106e-08 7.65344670082786 -0.266763637026528 5.3831838006558e-05 116.543447330587 27.05663347779 4.30738907064156 2.93097040583769e-05 -166.438741684856 118.367893808462 -1.40611390749404 0.161704824059077 SKAP1 other 0.408529818631769 1 0.284245509958139 4.30738907064156 -1.40611390749404 0.971111195322049 0.75618143389136 47.8287034565676 0.0158102013904273 0.987406274153647 -47.4433019089481 197.401556085869 -0.240339047217594 0.810387064476461 LRRC46 other 1 1 1 0.0158102013904273 -0.240339047217594 2.83630784588802e-07 121.618462106217 24.8735762614946 4.88946425828151 2.51867841855149e-06 -285.480591807294 102.659748322434 -2.78084250616567 0.00609894312913766 SCRN2 other 0.00271179393145354 1 0.0268239251575734 4.88946425828151 -2.78084250616567 2.27802986537006e-08 129.297927931197 20.6166877652186 6.27151797629344 3.82579491870419e-09 28.6541532097117 85.1706248400224 0.336432346992092 0.737027924798731 SSH2 other 0.000237393492270214 1 4.73365605291269e-05 6.27151797629344 0.336432346992092 0.062351058693148 17.6172142634693 8.28052442192624 2.12754813171255 0.0349880100942477 43.9834553098721 32.2514299341556 1.36376760347273 0.174656947300916 RHBDL3 other 1 1 1 2.12754813171255 1.36376760347273 4.50589882445974e-05 67.1513832308224 15.3514912507213 4.37425798797673 2.21905043034016e-05 -86.9052639987218 62.1229686503484 -1.39892323059861 0.163821054447202 ARSG other 0.344791378047659 1 0.217733228224977 4.37425798797673 -1.39892323059861 0.378956228634796 -4.62045721750489 5.58845368046383 -0.82678634944352 0.409605025706948 25.16600914435 22.6722886211477 1.10998980142112 0.268689898812362 ABCA8 other 1 1 1 -0.82678634944352 1.10998980142112 4.9340505826993e-10 625.533559760635 96.8184936423921 6.46088919820525 1.24341727447989e-09 -798.479648498568 383.412721854822 -2.08255908837816 0.0389131169587739 G6PC3 other 5.65688899306474e-06 1 1.5639702478408e-05 6.46088919820525 -2.08255908837816 9.41413989509003e-11 2106.66623024408 289.508750313612 7.27669276994919 1.56814041863645e-11 1106.42878518658 1126.81799100399 0.981905502059615 0.32766677230868 CLTC other 1.11595214316397e-06 1 2.08264728999107e-07 7.27669276994919 0.981905502059615 3.11955610189851e-10 221.868209818929 31.252426507511 7.09923147137412 4.40467570428557e-11 68.6076628710081 127.683367068783 0.537326548054213 0.591822679332621 BCAS3 other 3.61369378843923e-06 1 5.79258901870595e-07 7.09923147137412 0.537326548054213 5.78710042762936e-11 217.341654137502 29.3161912479192 7.41370706376899 7.32632151692703e-12 -21.3290362494511 114.103672825381 -0.186926815950019 0.85196089595498 PTRH2 other 6.91852361044114e-07 1 9.79529186813144e-08 7.41370706376899 -0.186926815950019 2.90513624831569e-18 561.12941281323 60.8647977160813 9.2192767226592 4.08735165649515e-16 11.2010191657151 168.208041248401 0.0665902716813285 0.947002891790014 SS18 other 4.06079944789567e-14 1 5.74722516419783e-12 9.2192767226592 0.0665902716813285 6.38059222357166e-06 37.0578799347245 14.2560675715257 2.59944614802065 0.0103454756653272 -81.6784370913044 34.1636097053095 -2.39080231263181 0.0181512619262906 TAF4B other 0.0536671611924612 1 1 2.59944614802065 -2.39080231263181 3.45438015860881e-15 390.62211668928 67.6295155936171 5.77591179325476 4.54028667528966e-08 -544.802901079021 180.976858345924 -3.01034566550863 0.0030822157096473 AFG3L2 essential 4.64441412324955e-11 1 0.000536661885019238 5.77591179325476 -3.01034566550863 1.98417187449217e-07 34.0251634390033 7.35885553259108 4.62370314083648 8.31166228804444e-06 -12.0166728341762 19.6923272866906 -0.610221060173921 0.542677201807583 PRELID3A other 0.00192722614169424 1 0.0849784352329664 4.62370314083648 -0.610221060173921 1.95524907259091e-05 130.4176537542 52.1520722366429 2.50071853640681 0.0134913802249161 -304.31852565883 137.932802069321 -2.20628103752933 0.0289160766940557 IMPA2 other 0.156595898223806 1 1 2.50071853640681 -2.20628103752933 6.74992226035036e-06 20.5182241022379 14.0413622855313 1.46127018767834 0.146061183913724 -129.582839679879 37.6671462764993 -3.44020857669079 0.000755502667756389 GNAL other 0.0566520975311206 1 1 1.46127018767834 -3.44020857669079 1.3202307404544e-18 482.079331170292 56.2688799614155 8.56742361854122 1.10606155977916e-14 15.2002519469675 143.882167613906 0.105643751404662 0.916004298456606 SLC39A6 other 1.84911517508043e-14 1 1.53753617424902e-10 8.56742361854122 0.105643751404662 5.10838764513074e-25 832.286549519741 80.0486459790207 10.3972595581176 1.84562046047363e-19 -22.7536816840518 204.688145666263 -0.111162674369774 0.911633999877812 RPRD1A other 7.35863240281083e-21 1 2.63849901029309e-15 10.3972595581176 -0.111162674369774 2.77607939376773e-16 96.1174949404093 13.1033516132894 7.33533662051219 1.23337427092129e-11 -24.5872819557326 33.5058852143505 -0.73381979907225 0.464188955121229 C18orf21 other 3.79739900273487e-12 1 1.6422378417317e-07 7.33533662051219 -0.73381979907225 2.32335448422734e-08 338.001488265598 71.2033504747531 4.74698853371296 4.75273036393977e-06 -114.158508463488 182.561244114895 -0.625316227532073 0.532707421344108 GALNT1 other 0.000241954135987435 1 0.0496470213817149 4.74698853371296 -0.625316227532073 0.225971575599938 8.52930921139462 7.37524989456341 1.15647731715259 0.249349290718539 -7.84092517430919 18.828595847945 -0.41643706400788 0.677693517296789 ASXL3 other 1 1 1 1.15647731715259 -0.41643706400788 0.429019011876619 -43.5137264054615 45.6443557042055 -0.95332107845817 0.342024923872783 -152.362779706509 120.786163403733 -1.26142577438468 0.209195108595416 ADCYAP1 other 1 1 1 -0.95332107845817 -1.26142577438468 2.67497186232465e-11 113.809380684964 22.9217832860802 4.96511895538587 1.87959953261131e-06 -120.771474333623 59.5750422548419 -2.02721592402744 0.0444475995311372 GAREM1 other 3.23912342808892e-07 1 0.0201981765774412 4.96511895538587 -2.02721592402744 3.77439635544614e-09 78.6114112086428 17.34391712182 4.53250616089162 1.31389737623155e-05 -93.5258946657663 48.637645569996 -1.92291163706044 0.0566950754914129 ESCO1 other 4.12805729395144e-05 1 0.131889018626123 4.53250616089162 -1.92291163706044 2.18242446478488e-16 286.170813615591 32.8969915902666 8.69899646690678 9.30710780020353e-15 1.73281302672454 100.016437453931 0.0173252824319273 0.986202322218695 OSBPL1A other 2.98904854696937e-12 1 1.29508405039832e-10 8.69899646690678 0.0173252824319273 0.135117485442892 -42.9321734058169 92.3956253540151 -0.464655910291441 0.642943407933201 369.801755669349 259.044195057335 1.4275624110685 0.155779323086434 GATA6 other 1 1 1 -0.464655910291441 1.4275624110685 0.00329203677158403 -15.5162351908732 5.77706074639914 -2.68583556102375 0.0082019473233547 -44.8522926722247 13.4870278009495 -3.32558761902065 0.00115382668671258 GREB1L other 1 1 1 -2.68583556102375 -3.32558761902065 4.1523572391373e-21 179.045540010557 16.7071504013543 10.7167012751644 7.70995504405567e-20 48.5731567398254 51.0842180106629 0.95084467632815 0.343357668861221 C18orf8 other 5.90257581543367e-17 1 1.10360296500613e-15 10.7167012751644 0.95084467632815 6.98624524658992e-32 1001.70470396201 67.1364020672682 14.9204406717885 1.20567476057286e-31 -538.405005688279 379.754466744502 -1.4177713571188 0.15829091935422 PELP1 essential 1.01412335999499e-27 1 1.75160429216025e-27 14.9204406717885 -1.4177713571188 8.76173226200992e-13 215.45071370301 31.3484302137912 6.87277519906647 2.0279825992121e-10 -89.9307291462183 95.8517763270717 -0.938227047971973 0.349778867634007 NPC1 other 1.11431710908242e-08 1 2.61893672862251e-06 6.87277519906647 -0.938227047971973 0.0363974314928334 -78.0570345373495 46.8748270594866 -1.66522288046612 0.0979555661783737 -250.967240206085 96.5387705553544 -2.5996523341074 0.0102642196180588 SLC14A1 other 1 1 1 -1.66522288046612 -2.5996523341074 1.72659206392987e-09 238.058094700133 35.0573484811661 6.79053336928847 2.28312153309433e-10 248.828184095484 198.30062963673 1.25480279387572 0.211451317629575 ARRB2 other 1.92497749207541e-05 1 2.94203040754535e-06 6.79053336928847 1.25480279387572 9.87004022596399e-11 118.904462809917 22.6684954205336 5.24536192650048 5.01065859498086e-07 -451.402038567493 122.256863782126 -3.69224291056523 0.000306862542177224 SLC13A5 other 1.16890886396092e-06 1 0.00558538113582516 5.24536192650048 -3.69224291056523 0.00267063677277837 40.2894560540081 12.0611845602438 3.34042281276507 0.00105258755207758 108.615784998325 67.1053540399433 1.61858597651796 0.107609521962439 ZMYND15 other 1 1 1 3.34042281276507 1.61858597651796 2.87553183256516e-12 148.268739123358 19.4062890979678 7.64024169561015 2.77963763414742e-12 7.63080139721833 98.5932456362 0.0773967967884461 0.938415325379809 WRAP53 other 3.60045340755483e-08 1 3.74806338588438e-08 7.64024169561015 0.0773967967884461 3.6887153197246e-13 818.546457504551 103.130382178573 7.93700595511434 4.34352352769702e-13 -524.060260271546 517.379470504688 -1.01291274615195 0.312722138365439 MINK1 other 4.74331902963386e-09 1 5.92977832001197e-09 7.93700595511434 -1.01291274615195 2.56373003301332e-11 166.878284003991 28.3184361481538 5.89292018566747 2.48843877807254e-08 -429.521582973063 150.366583479327 -2.85649625757517 0.00490451206547706 SAT2 other 3.10672805400555e-07 1 0.00029774169979638 5.89292018566747 -2.85649625757517 0.223541152520006 2.07355633216843 1.32365833016284 1.56653441822357 0.119276085702324 -2.57829921783981 7.15897957110154 -0.360148983836685 0.719229178878351 ASGR1 other 1 1 1 1.56653441822357 -0.360148983836685 0.648255178931919 -4.85416109178485 11.633912593142 -0.417242355305842 0.677101708494874 37.6199625367944 55.8322271482162 0.673803723375135 0.501480029528666 PIK3R5 other 1 1 1 -0.417242355305842 0.673803723375135 0.0417191846749149 572.125052662883 237.995269279043 2.40393455885075 0.0174825500560854 -62.7632028946007 1211.12477899214 -0.0518222432430373 0.958741655116989 TP53 ts 1 1 1 2.40393455885075 -0.0518222432430373 0.00191439529433114 154.218149409264 43.2054831939023 3.56941151930062 0.000474171525014537 109.385737791084 187.402883084568 0.583692929322341 0.560259250995529 CCDC40 other 1 1 1 3.56941151930062 0.583692929322341 0.000943063432063433 1348.14881326133 362.919500313232 3.71473236378248 0.000294520745452392 -1146.68033404497 1647.78301969257 -0.695892796770602 0.487666280464411 ARHGDIA other 1 1 1 3.71473236378248 -0.695892796770602 0.0126567629018259 249.942152566501 87.147109046544 2.86804869720934 0.00469453861667584 318.082786725095 342.066143611574 0.929886785540189 0.353848243933945 TMC6 other 1 1 1 2.86804869720934 0.929886785540189 0.134517775608872 19.2081171873215 11.7606262983034 1.6332563164678 0.104406279588628 61.4259809410635 51.0114715137201 1.20416014512623 0.230328501727647 CARD14 other 1 1 1 1.6332563164678 1.20416014512623 0.325655581725269 5.76696679504528 18.1907578639656 0.317027296947818 0.751649500161834 -109.535098105548 74.7095554920292 -1.46614576119696 0.14463437628437 TTYH2 other 1 1 1 0.317027296947818 -1.46614576119696 0.0157743865155593 99.4257514321582 36.45697331571 2.72720805896725 0.00728408669753298 -150.013260991904 174.85356781195 -0.857936517219022 0.392531127835844 RAB40B other 1 1 1 2.72720805896725 -0.857936517219022 1.65890283064416e-10 585.524383555382 82.0044863419693 7.14015061460991 3.20314391658014e-11 413.99330423456 355.692750787777 1.16390706112976 0.246216243563734 EIF4A3 essential 1.94423411751496e-06 1 4.22750934110247e-07 7.14015061460991 1.16390706112976 7.79981044373187e-06 709.316103294439 141.348155274974 5.01821974198785 1.60287650536708e-06 643.38585277968 638.865069920118 1.0070762717707 0.315686551585023 CSNK1D other 0.0650738185320549 1 0.0172950374929108 5.01821974198785 1.0070762717707 0.015809284842699 367.403239984929 125.700891905349 2.92283717653794 0.00405470943173942 60.532023106865 570.726552480852 0.106061340310421 0.915687702724102 ANAPC11 essential 1 1 1 2.92283717653794 0.106061340310421 0.01570411645797 284.196486857927 97.9833997895848 2.90045545947811 0.00438196395076826 294.74802439443 469.879701644381 0.627284011977823 0.531581793569099 TBCD essential 1 1 1 2.90045545947811 0.627284011977823 0.000406243375060039 145.587394121297 36.0556128665293 4.03785659282044 9.23406481817382e-05 147.768791215134 172.928577881762 0.854507641392674 0.394420264478554 FN3KRP other 1 1 0.848148853549266 4.03785659282044 0.854507641392674 5.21340595241907e-06 267.943727904085 51.8662078505155 5.16605587738996 8.76359590936861e-07 156.650881041881 250.660587775768 0.624952181082472 0.533097853211363 NARF other 0.0442670299419903 1 0.00960402475707706 5.16605587738996 0.624952181082472 1.63031140257141e-12 363.397903113749 45.4689935825295 7.99221347299354 3.46237472305332e-13 323.805659066504 209.337333327584 1.54681276349208 0.124044061305351 RPTOR essential 2.05663783434384e-08 1 4.73133505905236e-09 7.99221347299354 1.54681276349208 5.64018342769845e-09 681.972742096072 103.644458702875 6.57992477968484 1.09262977402759e-09 723.629861040965 497.09566483202 1.45571549348654 0.147919600651585 FOXK2 other 6.10042239539864e-05 1 1.37671351527476e-05 6.57992477968484 1.45571549348654 0.000133512932436826 115.473352256858 26.5592901026964 4.34775748185884 2.47191957188701e-05 -9.46559664313116 123.515889811213 -0.0766346472312089 0.939012392019635 TRIM65 other 0.962895268734386 1 0.241407665390485 4.34775748185884 -0.0766346472312089 2.91381070650635e-07 54.6846719457014 9.5324484914698 5.73668685381688 4.82971249491387e-08 23.9505090497737 40.8545452026816 0.586238542883146 0.55855711046042 CBX8 other 0.00278239784364291 1 0.000570389045649328 5.73668685381688 0.586238542883146 0.0583560595266476 -337.534857510868 149.290295827085 -2.26092965815954 0.025375363345361 481.943702034032 724.73737419597 0.66499082177003 0.507199242533464 SECTM1 other 1 1 1 -2.26092965815954 0.66499082177003 0.00535714845869098 95.4183769282361 32.126171962349 2.97011349625047 0.00344483027928586 215.266180415829 141.454915276059 1.52180063871038 0.130070586757292 RNF157 other 1 1 1 2.97011349625047 1.52180063871038 6.51477942185726e-08 177.326528569228 30.0388971810917 5.90323031835032 2.42011742417291e-08 240.318073309717 133.570233699924 1.79918883611158 0.0740684494696572 CEP131 other 0.00065812301719602 1 0.000289712256847739 5.90323031835032 1.79918883611158 0.506343321331414 3.30358472198381 15.6599306226628 0.210957813389219 0.833253074784983 87.350426616277 75.097246518799 1.16316417266258 0.246909988230013 ZNF750 other 1 1 1 0.210957813389219 1.16316417266258 0.00203250424326009 673.101528116476 189.277763393962 3.55615744843458 0.000528247249493873 793.842931559428 907.806908442362 0.874462315914211 0.383504329219792 WDR45B other 1 1 1 3.55615744843458 0.874462315914211 0.0953345617866161 85.4916101055805 39.9789753418987 2.13841423834552 0.0340301452220878 -71.9280731523391 171.343475574412 -0.419788806729918 0.675213636961012 CBX4 other 1 1 1 2.13841423834552 -0.419788806729918 0.0482368561992971 2.8335536775888 9.49508887350957 0.298423081167166 0.765796037181855 -30.3372087999448 19.1335516281239 -1.58555031442009 0.114961396905446 RNF165 other 1 1 1 0.298423081167166 -1.58555031442009 3.37122212900424e-23 240.582768859207 35.7357850038993 6.73226483853527 3.38051955446761e-10 -195.192219129938 72.1441602028262 -2.70558585173318 0.0076134574202422 DYM other 4.83096131086308e-19 1 4.32740308167398e-06 6.73226483853527 -2.70558585173318 0.137995575518641 0.792942353701785 5.17052107097955 0.15335830621643 0.878317801630493 -13.646757369988 10.4456994572202 -1.30644744527425 0.193360931171719 MAPK4 other 1 1 1 0.15335830621643 -1.30644744527425 3.48907618093904e-15 35.7059146354091 8.8825371702029 4.01978780963474 9.11643862028419e-05 -52.7744941702735 17.9611227038186 -2.93826254853508 0.00381187959911315 ELAC1 other 4.69071401765445e-11 1 0.83789187359032 4.01978780963474 -2.93826254853508 2.16566488493462e-19 283.134994417838 48.4811489355162 5.84010487858757 3.05608374832305e-08 -224.941361212842 98.0223776872927 -2.29479601005437 0.0231133386376161 MBD1 other 3.04925615798795e-15 1 0.000364162939450175 5.84010487858757 -2.29479601005437 3.62130083057356e-25 553.187665417193 74.5457740947793 7.42077833565531 7.52086197741109e-12 -329.063834986643 150.736863793714 -2.18303490403629 0.0305574275979663 SMAD4 ts 5.2182944968565e-21 1 1.00523841190077e-07 7.42077833565531 -2.18303490403629 0.645975728626829 -5.2289958244732 6.60363269155603 -0.791836261753239 0.42966629041461 -16.5611680076211 19.4492606677324 -0.851506300961718 0.395801797596819 TNFRSF11A other 1 1 1 -0.791836261753239 -0.851506300961718 9.92848560663187e-17 112.915917577668 15.7915348338363 7.15040803606529 3.26781406322624e-11 -75.1174785297008 46.5800855362175 -1.61265222390574 0.108867499261771 ZCCHC2 other 1.36586176490435e-12 1 4.31253421923966e-07 7.15040803606529 -1.61265222390574 0.00156183927110538 1.71479638923587 9.18335855656295 0.186728676515672 0.852122366568741 -43.8814886244373 17.4671932834298 -2.51222322398329 0.0130411598015765 FBXO15 other 1 1 1 0.186728676515672 -2.51222322398329 0.152136003146491 10.7496638881419 5.50589817441009 1.95239060869368 0.0527414504449162 13.2284843595949 9.7396314408658 1.35821200626653 0.17642226656987 CBLN2 other 1 1 1 1.95239060869368 1.35821200626653 0.155965697603565 4.41673192805217 30.237498196489 0.146068034443571 0.884056258158866 -68.4474882970176 57.0123692895385 -1.2005725976657 0.231736894224097 PMAIP1 other 1 1 1 0.146068034443571 -1.2005725976657 1.51637736680873e-05 242.009099094075 49.607923692889 4.87843636819587 2.64367114048268e-06 47.3315273251686 210.802407878056 0.224530297360497 0.822642326257391 P3H4 other 0.122872058032512 1 0.0281127989078928 4.87843636819587 0.224530297360497 1.06184030164007e-09 266.20999571765 39.6284832175325 6.7176428190891 3.36439444971735e-10 -119.188459067877 159.323306904034 -0.748091797640553 0.455545695537796 NT5C3B other 1.19722494009918e-05 1 4.30709777452815e-06 6.7176428190891 -0.748091797640553 1.50705477570391e-15 359.835990398738 39.0511304381172 9.21448332895141 2.0217519420282e-16 28.9006197828973 155.616178713693 0.185717320793935 0.852907704666089 RETREG3 other 2.04025075534796e-11 1 2.84783978554092e-12 9.21448332895141 0.185717320793935 2.95165927307029e-24 4082.57802823187 325.19730367199 12.5541570675191 3.29311996291747e-25 858.905229513549 1976.22669418739 0.434618777309212 0.664459622498802 ERBB2 og 4.24123920947469e-20 1 4.75691178643429e-21 12.5541570675191 0.434618777309212 4.0090756828279e-09 1079.51893550865 165.907824197208 6.50673915309425 1.08208585062129e-09 -626.696508947853 1007.06734200663 -0.622298512529588 0.534690409657952 GRB7 other 4.37670792294322e-05 1 1.36364458895295e-05 6.50673915309425 -0.622298512529588 2.54000581510604e-18 1075.39985197521 106.331293640538 10.1136722328489 1.17469368699062e-18 -754.202053844016 645.435342045216 -1.16851682068439 0.24445212897289 MIEN1 other 3.55270613358882e-14 1 1.67393850396163e-14 10.1136722328489 -1.16851682068439 6.69177244094635e-13 36.6813333333333 4.45347877384743 8.23655735124201 7.8163991591185e-14 30.7445714285716 27.1278483357759 1.13332141377486 0.258875508612 PNMT other 8.53870163464755e-09 1 1.07584918026107e-09 8.23655735124201 1.13332141377486 0.666030035236799 72.3971362011485 90.9666717085657 0.795864406615763 0.427352007805683 185.732638470498 348.391114254117 0.533115314574366 0.594732368655903 STAC2 other 1 1 1 0.795864406615763 0.533115314574366 0.489208300735808 360.526984685795 415.261264255463 0.868193149034012 0.386648352268014 -1109.66058792466 1705.97480178045 -0.65045543859532 0.516373635396967 IGFBP4 other 1 1 1 0.868193149034012 -0.65045543859532 0.0111452792859549 831.384595469256 281.680960852182 2.95151150064964 0.00365726397629954 1216.65317799352 1151.00861694853 1.05703220643041 0.292152204143774 FKBP10 other 1 1 1 2.95151150064964 1.05703220643041 6.1453675349521e-07 62.5738836689861 92.3151158565021 0.677829227515169 0.499253410074063 -596.054498243283 169.098460976523 -3.52489605642265 0.000611011013075644 TXNL4A essential 0.00570474468269604 1 1 0.677829227515169 -3.52489605642265 1.80356635337895e-13 110.139042756803 14.0724791326349 7.8265557702185 9.06976763450526e-13 -68.4492747995589 97.4170812252771 -0.702641404758061 0.483390448662583 CACNA1A other 2.33742199397912e-09 1 1.23267211920561e-08 7.8265557702185 -0.702641404758061 2.68978884587498e-11 288.03795915343 42.2643383434963 6.81515363644049 2.10644249216901e-10 -383.583710079766 306.619579597338 -1.25100853175619 0.212866197596591 SAMD1 other 3.25652735570084e-07 1 2.71752145914724e-06 6.81515363644049 -1.25100853175619 1.12549496315576e-35 1535.90301818349 93.5222786036272 16.4228571107967 3.00861728941315e-35 -116.753741981469 616.675509491145 -0.189327677497374 0.850093661188067 BRD4 og 1.63714497340637e-31 1 4.37723729436719e-31 16.4228571107967 -0.189327677497374 0.000374595493342239 110.056599393045 47.1351791836965 2.33491420418981 0.0209197414006461 -131.187857581135 69.4102566381587 -1.8900356220411 0.0607489641200187 SLC39A3 other 1 1 1 2.33491420418981 -1.8900356220411 8.44359785227731e-05 702.797187708704 377.05989186438 1.86388741648895 0.0643053022137729 -1482.70609647803 564.270308051552 -2.62765216478938 0.00949731841262236 NFIC other 0.625163984982612 1 1 1.86388741648895 -2.62765216478938 0.00355224023652987 60.3043435247562 27.4223230494102 2.19909682400351 0.029524252739066 -54.2743958166485 40.9271284612647 -1.32612274198558 0.186974009876992 TPGS1 other 1 1 1 2.19909682400351 -1.32612274198558 0.0242969420343214 -51.966688651246 170.428594456202 -0.304917662538143 0.760884948097468 -656.246911951759 254.360397046368 -2.5799885499948 0.0109179650672967 PLPP2 other 1 1 1 -0.304917662538143 -2.5799885499948 5.59405698856169e-06 120.360917349339 29.0464763419816 4.14373557509206 5.61965434967746e-05 -55.636365479763 55.6287122706927 -1.00013757659953 0.318812833993961 PRDM15 other 0.0473201280662433 1 0.528135115782688 4.14373557509206 -1.00013757659953 1.66446852207372e-05 523.126794542218 331.317955216601 1.57892678711065 0.116445424021096 -1947.49288680471 592.053208337722 -3.28938828365205 0.00124952216489703 PFKL other 0.134256030990466 1 1 1.57892678711065 -3.28938828365205 9.52501390543406e-08 138.259111670833 41.9823065757643 3.29327097407857 0.00122686714809157 -131.846008533675 74.0746617082653 -1.77990699509281 0.0770505039477162 FEM1A other 0.000949262885815558 1 1 3.29327097407857 -1.77990699509281 0.0464462808559781 8.06742038306626 16.2646033896789 0.496010888785989 0.620589329223706 -100.636678934589 52.4921664992792 -1.9171751833861 0.0570552079506147 VAV1 other 1 1 1 0.496010888785989 -1.9171751833861 5.17186636531857e-16 256.98376199326 29.3230945946125 8.76386907814549 3.62310447528729e-15 -229.916696266931 214.104733488869 -1.07385153294093 0.284602267063032 MVB12A other 7.05080541583881e-12 1 5.05894077884364e-11 8.76386907814549 -1.07385153294093 8.29161249326312e-06 250.357497498082 129.579587059605 1.93207512988077 0.0551859637080367 -497.264989652257 200.347236377096 -2.48201571753303 0.0141377493264529 SH3GL1 other 0.0690940069063616 1 1 1.93207512988077 -2.48201571753303 6.4232785065585e-11 129.285894624942 32.0678740430177 4.03163285634435 8.64013957677761e-05 -131.815345919113 61.6797732400801 -2.13709193459646 0.0341493091231242 DUS3L other 7.66682522542822e-07 1 0.79567045362545 4.03163285634435 -2.13709193459646 9.10983421343225e-07 294.916058541305 83.2104540970504 3.54421883333718 0.000521673968474389 -168.110833366931 142.731230304614 -1.1778139444896 0.240687715413223 DPP9 other 0.0083373202721332 1 1 3.54421883333718 -1.1778139444896 8.04108080099703e-21 253.22847208018 41.0227816738306 6.1728742359205 5.48902145565379e-09 -529.090574387773 108.651466692434 -4.86961281328579 2.70525668228769e-06 CCDC97 other 1.14159224131755e-16 0.0394074740908847 6.75369199903642e-05 6.1728742359205 -4.86961281328579 3.55496676811891e-06 21.0978633199592 5.82130489487195 3.62424983761708 0.000390999402399914 -20.29705482165 15.4739026357466 -1.31169591146072 0.191537604697521 TMEM91 other 0.0306971380427068 1 1 3.62424983761708 -1.31169591146072 7.85042688809423e-18 45.9308053732207 5.34255231133549 8.59716530538551 9.63115743995732e-15 -32.8884409743357 21.6273666720623 -1.52068633565178 0.130429808236128 ZFP14 other 1.09230839720943e-13 1 1.33998293462126e-10 8.59716530538551 -1.52068633565178 1.27724332845344e-06 85.3831522789655 20.3321104556283 4.19942398332437 4.58625225355485e-05 -23.4845169521013 35.1257013567355 -0.668584997452245 0.50479471560065 SIRT3 other 0.0115398934725768 1 0.435739826610247 4.19942398332437 -0.668584997452245 0.147629442314109 -5357.9471624077 3130.92430699331 -1.71129884885434 0.0891068198013919 -9425.08429659413 5408.97672270651 -1.74248934313736 0.0834861044897071 IFITM3 other 1 1 1 -1.71129884885434 -1.74248934313736 0.940771991029531 -99.3140874473271 579.71310606601 -0.17131592577108 0.864207796048971 -349.464336799784 1001.51086040473 -0.348937141488969 0.727629102828214 PGGHG other 1 1 1 -0.17131592577108 -0.348937141488969 0.0650620168825858 5.04677080590585 78.1452932739699 0.0645818909171197 0.948594644399996 -322.820218974078 153.819097932274 -2.09870050802284 0.0375531771303061 HUNK other 1 1 1 0.0645818909171197 -2.09870050802284 0.239960315103221 -2511.34331724838 1479.93638555072 -1.6969265312805 0.0919326865451229 -2396.03470116057 2648.32665824121 -0.904735333046798 0.367159901983274 COL6A1 other 1 1 1 -1.6969265312805 -0.904735333046798 0.00418218456792496 140.224079847555 81.2750770070692 1.72530233143131 0.0865745328288587 -341.153880174066 174.312609500341 -1.95713827675444 0.0522256994416584 IFNAR1 other 1 1 1 1.72530233143131 -1.95713827675444 0.000981706821795298 686.235542633899 269.634216662869 2.54506105021499 0.0119641398944524 -744.059092354516 529.585496720347 -1.40498389204836 0.162150185010979 SOD1 essential 1 1 1 2.54506105021499 -1.40498389204836 0.597184615362571 -1327.16385813933 1307.44457992949 -1.01508230521778 0.311817658316845 -1051.16183732261 2339.65484530726 -0.449280730202989 0.653923904312533 COL6A2 other 1 1 1 -1.01508230521778 -0.449280730202989 0.269904655421778 44.3351199902547 46.4940461020783 0.953565535959516 0.341817576341854 -67.2778657570959 88.079456584719 -0.763831526280874 0.446151674844176 SIK1 other 1 1 1 0.953565535959516 -0.763831526280874 0.222668890359701 1.17335520073732 35.5035539438225 0.0330489506091116 0.973678626982712 -95.5056981756078 63.4743246648526 -1.50463512104906 0.134479459614217 TRPM2 other 1 1 1 0.0330489506091116 -1.50463512104906 8.68036243552331e-07 509.581320959351 102.232169848877 4.98454959640033 1.72502955580589e-06 -313.263423072171 325.089263095741 -0.963622791134486 0.33681758966363 SCYL1 other 0.00795555217215711 1 0.0185699431682504 4.98454959640033 -0.963622791134486 0.00377816177600849 262.402906922778 89.6734790064892 2.92620415567672 0.00397666588535415 -79.6688870810104 192.324863958426 -0.414241224152027 0.679301268910774 TMEM50B other 1 1 1 2.92620415567672 -0.414241224152027 4.12773232075902e-09 5814.46815923037 1091.59103247599 5.32659941887007 4.31472248261017e-07 -2856.97612605443 2116.62320044814 -1.34978021853372 0.179450323139178 APP other 4.50087932255563e-05 1 0.00482817445804079 5.32659941887007 -1.34978021853372 0.000162126600706021 161.661905207317 43.976755748138 3.67607620109999 0.00033061567145512 -32.893782487272 84.591565777466 -0.388854162763758 0.697942896288477 DOPEY2 other 1 1 1 3.67607620109999 -0.388854162763758 2.29966931933721e-09 356.219699127097 67.1738374817575 5.30295294241358 4.07049665525818e-07 -206.994087785551 132.89072449777 -1.55762630212031 0.121457681677452 URB1 essential 2.54481406877856e-05 1 0.00456058445255127 5.30295294241358 -1.55762630212031 1.0463829488844e-14 2354.29295973273 270.743521959439 8.69565758284487 7.08845420019654e-15 877.469633758365 553.839938111194 1.5843379528585 0.115310535431179 AKT1 og 1.39514238574758e-10 1 9.8784697733939e-11 8.69565758284487 1.5843379528585 0.425213352756052 47.216229501917 56.2417328829646 0.839523021101979 0.402452415603452 128.161486374334 97.8580847585249 1.30966681690721 0.192221799407911 EMP3 other 1 1 1 0.839523021101979 1.30966681690721 9.46347553685346e-06 332.0265351802 109.014180058054 3.04571877716628 0.00272597100875267 -300.403185519188 210.460203486212 -1.42736337104638 0.15547381091795 SAE1 essential 0.0783575774451467 1 1 3.04571877716628 -1.42736337104638 0.00958995091226084 5.61075812458116 4.21529091592322 1.33104884965035 0.185102624623828 -10.4255999592817 7.35207598966132 -1.41804844970895 0.158158409349683 NTN5 other 1 1 1 1.33104884965035 -1.41804844970895 0.008368582844485 -68.0454263973604 32.4045356203136 -2.09987352371451 0.0373388851432939 -176.9066489655 56.5181889084526 -3.13008347192531 0.00208426231917464 LMTK3 other 1 1 1 -2.09987352371451 -3.13008347192531 1.0071426172297e-10 44.6164931420136 9.30215047401551 4.79636329971705 3.72654234764314e-06 -142.057129724352 39.2783100636568 -3.61668130563982 0.000401693286343868 GEMIN7 other 1.19255757306169e-06 1 0.0392442174630299 4.79636329971705 -3.61668130563982 6.58522453966445e-16 175.440637004457 22.8407376026124 7.68104078146716 1.63027966299475e-12 -249.167051463551 96.5688738879875 -2.58020044587623 0.0107965169484235 CBLC other 8.96775877811505e-12 1 2.206909579796e-08 7.68104078146716 -2.58020044587623 9.10064150960781e-08 111.816984547577 25.1047015404468 4.4540256480415 1.61153067518338e-05 -246.88427992862 112.063385666367 -2.20307711087401 0.029074691028407 WTIP other 0.000908790061149436 1 0.160298956260491 4.4540256480415 -2.20307711087401 0.00308419855214672 52.3144728991202 17.3296901527898 3.01877716438562 0.00298027789206603 2.62842044457754 57.5869074070369 0.0456426740543522 0.963655361893886 ADAMTS10 other 1 1 1 3.01877716438562 0.0456426740543522 1.34956506476694e-07 114.812182741117 24.8647108121554 4.61747508782566 8.57471122187963e-06 -66.5538886874545 54.3424674831411 -1.22471230641306 0.222697281830743 CAPN10 other 0.00132891671927601 1 0.0875906751315005 4.61747508782566 -1.22471230641306 0.907017072025787 -6.06335954428614 16.0486768802351 -0.377810556567036 0.706098389569019 -20.780129192997 53.2910707453328 -0.389936417158909 0.697129419374722 MYO1F other 1 1 1 -0.377810556567036 -0.389936417158909 7.32860558663164e-07 181.618454499238 48.6895396791996 3.73013291347312 0.000274566759240767 -114.782438004858 96.9272018419248 -1.18421285071298 0.238279804083629 ERVK3-1 other 0.00675770721143303 1 1 3.73013291347312 -1.18421285071298 3.85849907173129e-18 390.917723925744 65.9068809115458 5.93136435102123 1.86992001289168e-08 -495.433911224806 134.821387266347 -3.6747427190172 0.000326866136256453 ZNF787 other 5.38646470413688e-14 1 0.000224988775951127 5.93136435102123 -3.6747427190172 1.35605071430059e-22 80.070642959413 8.08380317853758 9.9050708176567 3.34772053082409e-18 -62.3283425354303 32.378534473528 -1.9249896126827 0.0560739435957592 TIMM29 other 1.9384744960927e-18 1 4.76213245509726e-14 9.9050708176567 -1.9249896126827 2.40217989274959e-10 481.526352591068 75.7090417617028 6.36022252278257 2.1819706758327e-09 87.7601360422445 249.219552295675 0.352139851122619 0.725214802051346 FBN3 other 2.79565695918198e-06 1 2.72353579757437e-05 6.36022252278257 0.352139851122619 2.03310148949052e-22 1014.90588260563 95.8551648047633 10.5879102568211 5.03039844654581e-20 -189.605338183693 387.914692341717 -0.488781017906557 0.625692082595732 CARM1 other 2.9046920980351e-18 1 7.20353057545361e-16 10.5879102568211 -0.488781017906557 4.74742495960707e-07 71.3660348861805 23.7115934537517 3.00975280406087 0.00306193013530043 -176.823422732691 68.653034047207 -2.57560973359319 0.0109597176748826 EVI5L other 0.00445403409710335 1 1 3.00975280406087 -2.57560973359319 0.660367899420364 6.83688409969563 9.11571144027394 0.750011027059253 0.454377704812779 -5.99461215760476 25.5702715246873 -0.234436781471685 0.814953316481036 SLC47A1 other 1 1 1 0.750011027059253 -0.234436781471685 2.97580284634102e-08 410.354077016442 70.8378113532399 5.7928678085517 3.92801502512277e-08 -358.980672330721 334.987297257327 -1.07162473105648 0.285609774531391 PSMB6 essential 0.000307668256283198 1 0.000465901862129812 5.7928678085517 -1.07162473105648 0.00968251368943892 47.0609624693322 15.344411519368 3.06697734285417 0.00254711839560703 60.4904863735825 29.5565526860456 2.04660154437231 0.0423649449451194 SIGLEC10 other 1 1 1 3.06697734285417 2.04660154437231 5.24647787526617e-12 117.832038772628 21.951943952611 5.36772684127653 2.81833179161663e-07 -56.1125176531007 37.9921098769054 -1.47695186803011 0.141691607362471 ZNF473 other 6.50982974763026e-08 1 0.00318781508949757 5.36772684127653 -1.47695186803011 2.58712306382748e-07 230.07497877959 48.7408584003124 4.72037190830672 5.20138028102386e-06 4.78523541109421 87.6395407492113 0.0546013291510462 0.956525943683972 FAM71E1 other 0.00248415556588715 1 0.0541255632043343 4.72037190830672 0.0546013291510462 0.00720467040213371 4034.89303923974 2448.26912722258 1.64805943692028 0.101340282462198 -5207.96385191709 4319.42207516768 -1.20570848629441 0.229743883491168 RPS11 essential 1 1 1 1.64805943692028 -1.20570848629441 0.000139825627541445 5474.38461826147 1919.75168024002 2.85161079665107 0.00493530060860756 -3093.54381485067 3386.97151153314 -0.913365761807177 0.362450694872332 RPL13A other 1 1 1 2.85161079665107 -0.913365761807177 4.46674375868155e-10 81.8378018634726 20.8812815974803 3.91919439817084 0.000132341146009553 -100.94694808899 39.7129041510011 -2.54191805527891 0.0119932797790102 CTU1 other 5.13228857872511e-06 1 1 3.91919439817084 -2.54191805527891 4.77446732138451e-08 224.27041874265 59.8246854625756 3.74879394698944 0.000249331789993817 -174.204210281365 105.547247299631 -1.65048558572853 0.100842737412456 NOSIP other 0.000486184007336585 1 1 3.74879394698944 -1.65048558572853 0.055424599775937 109.641502552881 48.0314545029825 2.28270211026137 0.0237900934197884 55.9135667396061 92.5186484872948 0.604349151806778 0.546483882982457 IGLON5 other 1 1 1 2.28270211026137 0.604349151806778 0.00442349251706434 394.114066545052 124.964596627924 3.15380577523494 0.00193139905265769 215.741170750762 220.472018899909 0.978542183390198 0.329311669373311 RCN3 other 1 1 1 3.15380577523494 0.978542183390198 3.46103725806524e-07 82.1297153453781 20.0312766824948 4.1000739317405 6.62717442881367e-05 -38.9491028813062 38.8463948746706 -1.00264395208274 0.317585372019979 ZNF614 other 0.00328452435790392 1 0.618050287231163 4.1000739317405 -1.00264395208274 0.886577275297688 3.37505142763107 20.4909371801609 0.164709471214365 0.869390070406821 20.5134534682794 43.6045642734832 0.470442803639115 0.638708627839175 SLC2A5 other 1 1 1 0.164709471214365 0.470442803639115 1.08942748484539e-17 4181.93016785805 490.511816279292 8.52564612934199 1.36425181030966e-14 539.187262888864 1039.603232457 0.5186471588921 0.604756123481522 RERE other 1.51408631843812e-13 1 1.89480933933909e-10 8.52564612934199 0.5186471588921 0.0667642342732123 -32.2342973999414 30.3017008473906 -1.06377848432614 0.289300467055513 -159.373411237706 68.2352918806864 -2.33564489643248 0.0209613735542387 MMEL1 other 1 1 1 -1.06377848432614 -2.33564489643248 0.177866734685138 -11.3936366814844 9.8424546878882 -1.15760113130163 0.249055838408022 -40.988871684731 22.0074085838788 -1.86250332602798 0.064689743565284 CFAP74 other 1 1 1 -1.15760113130163 -1.86250332602798 0.601349016456149 -4.15792798483893 11.7531491128019 -0.353771397344903 0.724050119915829 15.7735050293989 26.2241743882143 0.601487192538188 0.548502352899493 PRDM16 og 1 1 1 -0.353771397344903 0.601487192538188 0.502551707312794 18.1767694099248 16.4857337435731 1.10257569924729 0.271920467141273 10.5069265907953 36.5421297910733 0.287529124625955 0.774091265092951 PADI3 other 1 1 1 1.10257569924729 0.287529124625955 0.067779870861444 10.0364600746493 22.4010502001289 0.44803524767743 0.654753365831101 -83.9915539892466 52.1310052807465 -1.61116313673443 0.109178658906303 FHAD1 other 1 1 1 0.44803524767743 -1.61116313673443 0.000126795432539987 286.335121614401 108.905213105418 2.62921409774237 0.00943769075552459 -328.674153498704 244.189893627232 -1.34597770864523 0.180313765223383 EPHA2 other 0.917998931589508 1 1 2.62921409774237 -1.34597770864523 2.01949529689311e-06 221.061582334296 53.7381679898783 4.1136791707513 6.35875993283908e-05 -53.395032956096 120.493015448844 -0.443137992332553 0.658295978426886 ARHGEF19 other 0.0179065485643664 1 0.594671228919111 4.1136791707513 -0.443137992332553 0.00814296443496453 171.790687190673 128.022450810447 1.34187938211737 0.181597551143446 -459.816385589713 297.92973988403 -1.54337188952234 0.124779759365886 EFHD2 other 1 1 1 1.34187938211737 -1.54337188952234 2.8194429672533e-25 200.292428029353 22.6291138657788 8.85109462161699 1.85794992998221e-15 -142.272712742945 51.8417499160261 -2.74436555427623 0.00677870480557093 PEX14 other 4.0639450929989e-21 1 2.6000151320171e-11 8.85109462161699 -2.74436555427623 1.93932955821853e-15 1154.60909857729 147.365063534858 7.83502596125287 7.15179139165206e-13 120.660743406625 338.057367031625 0.35692386906432 0.721637401266092 PGD essential 2.62100389793234e-11 1 9.73358808403845e-09 7.83502596125287 0.35692386906432 0.00107183531352196 34.4331308130814 13.9241345467289 2.47290994621784 0.0144815004248567 -23.6773739873986 30.8791574294575 -0.766775260675064 0.444381445836666 MYOM3 other 1 1 1 2.47290994621784 -0.766775260675064 0.000171565362931927 521.981127946213 317.482456134436 1.64412589691313 0.102190104132681 -1508.75522993741 671.063305543815 -2.24830536474461 0.0259760862647237 SH3BGRL3 other 1 1 1 1.64412589691313 -2.24830536474461 3.23847363420293e-12 238.849164991729 52.7744356781749 4.52584972103275 1.19133716403302e-05 -293.866754356236 111.589694783091 -2.6334578199847 0.00930848616609557 CNKSR1 other 4.0471205006634e-08 1 0.12013443962109 4.52584972103275 -2.6334578199847 4.65926095322851e-05 2548.83448083364 1153.23890174705 2.21015305412643 0.0285991786315463 -4796.16258174278 2543.5210098636 -1.88563906613847 0.061264332492864 RPL11 essential 0.355920944217126 1 1 2.21015305412643 -1.88563906613847 5.50149901002261e-06 48.1643414341434 11.2057566862662 4.29817840799397 3.03140940728939e-05 10.0745949594959 24.8506881106445 0.405405070259628 0.68573880803535 IL22RA1 other 0.0465756906188514 1 0.293592001095978 4.29817840799397 0.405405070259628 0.0159986613952073 -9.46376933169139 48.5222130945242 -0.195039935900191 0.845617108388106 -253.453766680872 102.598519147355 -2.47034527191231 0.0145816876308785 ZNF593 other 1 1 1 -0.195039935900191 -2.47034527191231 1.07503899468225e-06 51.339703828588 14.2210905246092 3.61011019089895 0.000418252414607569 -118.533536316856 49.6212140748152 -2.38876735539238 0.0181653623618823 C1orf216 other 0.00978607996859255 1 1 3.61011019089895 -2.38876735539238 2.69929085186652e-10 423.747283155566 73.324130757789 5.77909726001835 4.24274502113662e-08 -365.561886326805 240.523155129954 -1.51986151241569 0.130664954431841 KIAA0319L other 3.13630604078371e-06 1 0.000502298583052365 5.77909726001835 -1.51986151241569 0.0486430348366783 132.329006005117 81.6637286900164 1.6204134703109 0.107286691968532 -335.82985249125 289.748162985371 -1.1590404889235 0.248318997279332 EVA1B other 1 1 1 1.6204134703109 -1.1590404889235 0.000125335642582765 70.2046822949007 29.1917153243856 2.40495227891779 0.0173458621482637 -50.9130886747336 43.2497285259549 -1.17718863007845 0.240913160986969 PLK4 essential 0.908056730512129 1 1 2.40495227891779 -1.17718863007845 0.000712634858965867 4.40659923451929 50.3147042185117 0.0875807440978263 0.930327501542212 -362.958074286116 111.444077481172 -3.25686283640723 0.00139493244541261 MAP3K6 other 1 1 1 0.0875807440978263 -3.25686283640723 0.0396782716323644 -3.13505292081593 2.0660700124899 -1.51739916937169 0.131270669909546 -11.7043288038205 4.56762577690926 -2.56245353176468 0.0113786321731556 FCN3 other 1 1 1 -1.51739916937169 -2.56245353176468 4.23895102941909e-18 150.477141028831 24.0433275698038 6.25858216139003 3.77086445496998e-09 -142.897810089232 50.7826207799308 -2.81391168660805 0.00554196333784966 GPN2 essential 5.91588005665728e-14 1 4.66644476302535e-05 6.25858216139003 -2.81391168660805 0.00369922134657624 30.9456943317377 66.7875801703667 0.463345044884082 0.643793153623326 -386.873186137007 147.930518024348 -2.61523579653341 0.00983351235790281 SYTL1 other 1 1 1 0.463345044884082 -2.61523579653341 2.9572251319048e-15 890.648839818028 127.2034387882 7.00176699861867 7.47269391217882e-11 -322.196472714433 279.752831085304 -1.15171836318677 0.251233345786968 WDTC1 other 3.98131219508343e-11 1 9.77204182895624e-07 7.00176699861867 -1.15171836318677 4.02150983466814e-08 80.1253982937608 15.2825111318957 5.24294715719418 5.13604211680348e-07 17.1402651865557 35.6273877701959 0.481098005195159 0.631129687720443 NBPF3 other 0.000411923252365058 1 0.00572052370969571 5.24294715719418 0.481098005195159 5.01880633850272e-13 5299.93800911225 788.53904648303 6.72121188259548 3.58319811309621e-10 446.810096136378 1685.037953586 0.265163223881991 0.791250214247208 HSPG2 other 6.43059656152353e-09 1 4.58362702627267e-06 6.72121188259548 0.265163223881991 2.75381498659829e-08 36.547127370427 16.490879714837 2.21620241020527 0.0281250509811898 -269.883265470475 53.6294106143682 -5.03237425842918 1.32022130832706e-06 ITGB3BP other 0.000285432923360913 0.0192580682245668 1 2.21620241020527 -5.03237425842918 6.63726984308434e-07 1149.74302732152 294.987534161563 3.89759869205798 0.000143564427685688 -2377.79702390632 890.573314152361 -2.66996213126989 0.00838422374343177 SERBP1 essential 0.00614943050961764 1 1 3.89759869205798 -2.66996213126989 8.08151269934006e-05 -15.0594023149551 27.2315252977348 -0.553013544056152 0.581056016525734 -390.087609525174 87.7850530907196 -4.44366775198104 1.68184401959911e-05 BCL10 other 0.600213948179986 0.243648743119322 1 -0.553013544056152 -4.44366775198104 0.542441776543167 -251.770192169913 409.980957715062 -0.614102161166457 0.540053951126472 -1380.67295026721 1321.63732092504 -1.04466855498667 0.29781320814855 CYR61 other 1 1 1 -0.614102161166457 -1.04466855498667 0.0550468692604692 14.6281674907294 30.3805370254053 0.481497989271776 0.630846099964506 -206.756103213844 96.8486213543091 -2.13483785646728 0.0343565372434525 PRKACB other 1 1 1 0.481497989271776 -2.13483785646728 1.97104742376063e-07 128.835271288334 28.7528163384893 4.48078789123246 1.43142896890696e-05 -183.426497222434 85.6278041410503 -2.14213711378473 0.0337342984203017 PIGK other 0.00191526678166821 1 0.142999753993806 4.48078789123246 -2.14213711378473 0.00462860963546087 -62.0732076045368 94.1322989890765 -0.659425173624411 0.510607676487811 -775.978142445714 245.28940816091 -3.16352079065995 0.00187827222104907 TINAGL1 other 1 1 1 -0.659425173624411 -3.16352079065995 7.59305183258953e-06 18.9313251746415 5.54332708426559 3.41515571548663 0.000817626732437507 -28.7912330329474 15.8073378951776 -1.82138404479422 0.0705147098830859 AZIN2 other 0.0633867966984574 1 1 3.41515571548663 -1.82138404479422 0.0119441571094141 6153.50996739445 2305.34890279572 2.66923152496874 0.00842855038514426 -5522.60786660614 8710.85057670418 -0.633991803438289 0.527039104988151 RPS8 essential 1 1 1 2.66923152496874 -0.633991803438289 0.000196451483629149 157.499651810585 50.2506662773572 3.1342798708632 0.0020655968031981 -381.048978644383 197.955217933565 -1.92492515540695 0.056094147478097 KIF2C other 1 1 1 3.1342798708632 -1.92492515540695 5.93267868287945e-13 6161.43804303757 800.269836595619 7.69920064618277 1.62392105268968e-12 -2501.08307479764 3488.29534528411 -0.716992922683254 0.474478774722481 PTPRF other 7.58492969606138e-09 1 2.19846432113128e-08 7.69920064618277 -0.716992922683254 0.162282553322001 5.04566495683724 7.01978023710716 0.718778193392071 0.473388394694831 -40.1465865966054 26.5009914071708 -1.51490885679629 0.131885956969297 BEST4 other 1 1 1 0.718778193392071 -1.51490885679629 1.96900438797887e-05 66.1801313160149 30.5545796850255 2.16596438236881 0.0318326327637095 -360.11590065658 102.815811727776 -3.50253423675781 0.000601374978672849 MOB3C other 0.157618801257708 1 1 2.16596438236881 -3.50253423675781 0.00826980564658252 827.420391906077 313.47151437965 2.63953933276367 0.00915029659245337 -903.582221727918 1028.90436580643 -0.878198452408851 0.381195309903208 CYP4B1 other 1 1 1 2.63953933276367 -0.878198452408851 0.00479099981161812 42.5385300172482 13.8826935696392 3.06414096110843 0.00257787838026851 -8.23380626495292 40.2217778973555 -0.204710151947169 0.838068897770199 TMEM61 other 1 1 1 3.06414096110843 -0.204710151947169 0.0147563296345968 -93.1009836671233 231.141864316663 -0.402787197128322 0.68766337294987 -2218.19660001129 758.193589476929 -2.92563354636327 0.00395785522770171 LMO4 other 1 1 1 -0.402787197128322 -2.92563354636327 1.5860020119265e-10 153.655314661456 26.8855758785706 5.71515802210984 5.46162697856555e-08 -254.164309419683 87.5090517385042 -2.90443450557755 0.00421718395804303 MTF2 other 1.86149056139814e-06 1 0.000643379658075021 5.71515802210984 -2.90443450557755 0.222825474370587 7.26303612742486 18.2896506488727 0.397111802016433 0.69183483657948 -87.7391291451622 56.8428337412041 -1.54353897176597 0.124752482190534 SLC44A3 other 1 1 1 0.397111802016433 -1.54353897176597 8.98243149462538e-08 200.506059832877 36.2020738193447 5.53852414183345 1.30977382471392e-07 -78.4433246156786 127.935404227639 -0.613147901390161 0.540694920879761 IGSF3 other 0.000897524554942968 1 0.00151252681277963 5.53852414183345 -0.613147901390161 2.76443904194543e-07 229.812146980324 60.7645946664007 3.78200740483828 0.000223137422874376 -611.917975296382 203.594104672968 -3.00557806562868 0.00310185198258616 CTTNBP2NL other 0.00264584460704597 1 1 3.78200740483828 -3.00557806562868 2.50482465881816e-08 228.392640950148 42.8009561013925 5.33615745426578 3.38714745774752e-07 -243.373476028852 144.614568732207 -1.68291119050062 0.0944452095527148 STRIP1 essential 0.000260316437049276 1 0.00381155703420329 5.33615745426578 -1.68291119050062 4.18247952919902e-05 0.726961754847164 103.684532413191 0.00701128449854183 0.994415166234015 -1478.06759061416 334.4608857639 -4.4192539502438 1.88850979478035e-05 PSMA5 essential 0.321172603047193 0.273437333186247 1 0.00701128449854183 -4.4192539502438 0.90399836574356 0.972364941443212 30.2730645975228 0.0321198053243271 0.974418100282705 -40.837703060068 97.9361103415785 -0.416983101714328 0.67727144348377 C1orf162 other 1 1 1 0.0321198053243271 -0.416983101714328 0.910117322063525 4.86350720949958 52.0495499876425 0.0934399473319992 0.925674727563098 -66.5276929601358 176.600190888175 -0.376713595979417 0.706901664219656 CD53 other 1 1 1 0.0934399473319992 -0.376713595979417 0.118175729453269 -8.42037163702691 4.77855921943508 -1.7621151586403 0.0800468728089155 -25.4582763337893 16.06996576405 -1.58421472127476 0.115209662319168 PROK1 other 1 1 1 -1.7621151586403 -1.58421472127476 1.48603099470287e-05 1481.30638887409 426.578410561677 3.47253014263813 0.000679818226583463 -2980.27123141685 1347.49817477373 -2.21170706366062 0.0285518676424381 CELSR2 other 0.120502253360455 1 1 3.47253014263813 -2.21170706366062 0.652784221292114 -15.7278248407775 52.9469536090537 -0.297048720817965 0.76682959888917 184.914485868097 225.321508169074 0.820669484110426 0.413103076751758 RGL1 other 1 1 1 -0.297048720817965 0.820669484110426 0.451305335868357 19.3706958623246 27.8202042059805 0.696281584380336 0.4872952959771 -59.7867749800387 85.6396546035813 -0.698120225458482 0.486148017475394 LYPLAL1 other 1 1 1 0.696281584380336 -0.698120225458482 0.428865848010766 -3.43913038399084 2.96264659645808 -1.16083045075386 0.247507118665503 4.47927789005581 10.9427704187178 0.409336732715688 0.682861318595266 LHX9 other 1 1 1 -1.16083045075386 0.409336732715688 0.659219139254771 -1.63411326401771 5.89667117255827 -0.277124705820886 0.782053590788002 -16.7620925628595 18.3777261779982 -0.912087404095023 0.363139106793518 SYT14 other 1 1 1 -0.277124705820886 -0.912087404095023 0.0298785376803232 29.2402638375301 21.7783680498886 1.34262878515728 0.181342618395796 -108.188031930504 65.1028220479592 -1.66180249222999 0.0985606001483602 DTL essential 1 1 1 1.34262878515728 -1.66180249222999 0.148778950195072 11.6142112245842 12.2471392685703 0.9483203358673 0.344433137310876 -61.8641880842924 44.0129089139309 -1.40559189589741 0.161833815537788 DYRK3 other 1 1 1 0.9483203358673 -1.40559189589741 6.39914082319822e-11 314.741760513406 49.3600344682362 6.37644936645954 1.95435264008306e-09 -341.415976057512 177.386625023051 -1.92469965541735 0.0560868563991504 EIF2D other 7.63929431473404e-07 1 2.44352710589585e-05 6.37644936645954 -1.92469965541735 6.73440798402225e-05 75.3832680489643 25.8193715861172 2.91963992220079 0.00402364922372796 -163.702365890805 77.120829404177 -2.12267382438108 0.0353596974084849 INTS7 essential 0.504878566562148 1 1 2.91963992220079 -2.12267382438108 0.0299656579549999 19.9017593167135 12.3017823306709 1.61779478629648 0.107727022437776 -48.7590612110814 35.913716337963 -1.35767239325049 0.176528325286728 VASH2 other 1 1 1 1.61779478629648 -1.35767239325049 4.28397748297495e-12 31.8631660699941 4.88629748878943 6.52092226130263 9.21056248955035e-10 -28.6370866070526 15.2415122186806 -1.87888748807706 0.0621253555065432 TAF1A other 5.33269517080722e-08 1 1.16375457055469e-05 6.52092226130263 -1.87888748807706 0.0226286573991666 65.1622698804328 50.545522322534 1.28917986967527 0.199243843656367 -269.513664832037 150.403728894386 -1.79193472670675 0.0750816658114246 SMYD2 other 1 1 1 1.28917986967527 -1.79193472670675 0.339092722950014 56.3678943614571 75.5778525979595 0.745825561640513 0.456895146986309 -224.867960941904 240.597331946497 -0.934623668195577 0.351426730844805 SUSD4 other 1 1 1 0.745825561640513 -0.934623668195577 0.598437222515996 10.4633630913874 29.0106497911725 0.360673172324849 0.718834841829823 -68.267714667702 90.8799194902165 -0.751185906090632 0.45367976056155 DUSP10 other 1 1 1 0.360673172324849 -0.751185906090632 0.739532687564984 1.50540995431596 4.9252505922938 0.305651443740015 0.760277527672039 -8.61767518901441 15.3459496174815 -0.561560242527938 0.575221529247222 HHIPL2 other 1 1 1 0.305651443740015 -0.561560242527938 1.16604674116017e-11 369.988315623671 53.7080680523521 6.88887776158739 1.28163532191017e-10 -138.941941890963 170.716137814536 -0.813877022229191 0.41694806821108 TP53BP2 other 1.43073935140353e-07 1 1.66445979256474e-06 6.88887776158739 -0.813877022229191 2.24762769146222e-07 50.5466976358117 10.848435106871 4.65935382733654 6.72436340936934e-06 -57.3351657553097 34.3634180307336 -1.66849426049617 0.0972107403703246 C1orf131 other 0.00216985977333762 1 0.0693012892969604 4.65935382733654 -1.66849426049617 3.40263832622077e-08 642.622669773637 127.048314524834 5.0580967734761 1.16236930661755e-06 -663.766991836972 401.432806232634 -1.65349463604206 0.100215745998911 GALNT2 other 0.000350301615684429 1 0.0126558770104519 5.0580967734761 -1.65349463604206 0.000387014470196603 50.3079227696406 16.4265366833166 3.06260070150607 0.00257993737452849 -76.5248364499508 51.9027012843855 -1.47439024475153 0.142366274624314 TTC13 other 1 1 1 3.06260070150607 -1.47439024475153 3.29190386457873e-06 172.440752512671 39.0311066339798 4.4180339063855 1.87589999644947e-05 -105.00877244223 123.536442524696 -0.850022635395523 0.396640696707848 SCCPDH other 0.028520650019574 1 0.18543271464903 4.4180339063855 -0.850022635395523 0.660267869666233 8.96815496947888 15.6918569115956 0.571516489093895 0.568461700570183 -23.3511347434562 50.3939029205673 -0.463372221442405 0.64373524508496 LYST other 1 1 1 0.571516489093895 -0.463372221442405 8.98282980635882e-07 199.163227016886 40.5498801437627 4.91156142288921 2.24862263461591e-06 -71.0716697936206 129.489001741168 -0.54886259711604 0.583879468192621 MAP3K21 other 0.00822467897070214 1 0.0240242842282364 4.91156142288921 -0.54886259711604 3.5182201200349e-08 462.266236212001 108.315829771012 4.26776249777401 3.5615428086395e-05 -842.382141511973 311.897615694503 -2.70082905134186 0.00774645917928576 ACP1 other 0.000361778574943189 1 0.34212180219791 4.26776249777401 -2.70082905134186 3.24591092171374e-12 225.67950670326 36.6588351308652 6.15621052599261 6.3385626463562e-09 -269.797157061744 117.100112111719 -2.30398717982733 0.0225780435402577 SNAP47 other 4.05576569668132e-08 1 7.78312107346078e-05 6.15621052599261 -2.30398717982733 5.9592281311016e-05 505.267113622931 197.025996857311 2.56446926640271 0.0112649867339014 -1711.20047281324 638.62606293119 -2.67950303336996 0.00815422664887661 SRP9 essential 0.449623762491616 1 1 2.56446926640271 -2.67950303336996 8.61864175307767e-10 96.1250905448099 16.994064423822 5.65639202885822 7.13326714470081e-08 -106.309724897896 56.1959284911066 -1.89176916820087 0.060363075463967 NVL essential 9.764921106237e-06 1 0.00083494891928723 5.65639202885822 -1.89176916820087 1.13147837689586e-08 100.077794432881 19.2838637238566 5.18971695019146 6.42844910584825e-07 -104.472459535866 61.6600718433549 -1.69432918925678 0.0921854947218123 SDE2 essential 0.000120219577545185 1 0.007108579021247 5.18971695019146 -1.69432918925678 0.0864161556548097 177.016888183463 106.397389990567 1.66373336976741 0.0981604960291418 -282.980864508855 347.148878812602 -0.815157074615279 0.416217265123098 DEGS1 other 1 1 1 1.66373336976741 -0.815157074615279 4.16732222711347e-12 168.982944937253 25.8490577755997 6.53729611362334 8.33429716829528e-10 -157.590470822084 84.3392063090758 -1.86853158475983 0.0635511965685926 FBXO28 other 5.18873290497898e-08 1 1.05495533556282e-05 6.53729611362334 -1.86853158475983 0.0554884412459104 47.4242985535877 20.2251678840035 2.34481606410281 0.0202960540260084 15.7482186341721 64.6918438767156 0.243434375810709 0.807988736420485 LEFTY2 other 1 1 1 2.34481606410281 0.243434375810709 0.108126039074238 43.8589870540185 40.7927427650045 1.07516641640592 0.283949757758436 -185.535992525237 134.893336767917 -1.37542740783742 0.170958271407657 CNIH4 other 1 1 1 1.07516641640592 -1.37542740783742 0.00705101737180154 199.842343894592 73.161471316329 2.73152439800631 0.0070261588532485 -128.919661905518 235.432226084992 -0.547587150872786 0.584753030792 ITPKB other 1 1 1 2.73152439800631 -0.547587150872786 0.453726234047887 252.572856161389 255.660792674459 0.987921743960944 0.324883244318558 -255.97167572294 806.162798537569 -0.317518590770114 0.751319849331284 GUK1 essential 1 1 1 0.987921743960944 -0.317518590770114 2.64562499695921e-06 448.394587929362 91.4441888050602 4.90347821757427 2.34272399930189e-06 -36.2784475549241 297.900921907494 -0.121780246004709 0.903229788474622 CDC42BPA other 0.023154509973387 1 0.0249968650725512 4.90347821757427 -0.121780246004709 0.0617706708905873 12.6097923248825 7.61284790518366 1.65638306215159 0.0996414978773232 -26.9075884256762 25.1741458561069 -1.06885804902687 0.28677426686952 CNIH3 other 1 1 1 1.65638306215159 -1.06885804902687 5.25804498396122e-08 105.885189335325 20.4211085834604 5.18508527108488 7.18286703008191e-07 -64.0029480817455 63.2294921243361 -1.01223251889938 0.313124691023993 C1orf35 other 0.000534164789920621 1 0.00791623775385327 5.18508527108488 -1.01223251889938 6.05893373857825e-07 267.658177994331 54.9884598831255 4.86753363457026 2.75854691245469e-06 -186.624033893729 171.803144080945 -1.0862666972253 0.279047461655282 MBOAT2 other 0.00563238480338234 1 0.0292957682102688 4.86753363457026 -1.0862666972253 1.07286219968284e-10 1027.21421297784 162.00150491607 6.3407695719248 2.32024348784554e-09 -546.746886022817 521.317768017556 -1.04877853694103 0.295891849161543 PARP1 other 1.26908869600483e-06 1 2.89334362934338e-05 6.3407695719248 -1.04877853694103 9.52382820754843e-12 102.566448336274 14.736702986693 6.95993184017413 8.87947267295572e-11 -35.4006983316954 48.0082710884065 -0.737387486137661 0.461994393935253 PSEN2 other 1.17209753750298e-07 1 1.15912636272764e-06 6.95993184017413 -0.737387486137661 0.000567699229856731 146.425141201388 48.4284105450374 3.02353803384102 0.00291624255864764 -220.571446431723 157.172599938744 -1.40337085801016 0.162468508397313 LBR other 1 1 1 3.02353803384102 -1.40337085801016 0.117013297183462 13.8179892230461 14.1627561119045 0.975656794049528 0.330795009309658 -60.282604053709 45.2560313113639 -1.33203469917548 0.184855771849409 WNT9A other 1 1 1 0.975656794049528 -1.33203469917548 0.0849318298947791 453.396744609459 352.568196173467 1.28598310775139 0.200330363441865 -1463.90724732542 1132.75025662464 -1.29234775164612 0.19812361499194 EPHX1 other 1 1 1 1.28598310775139 -1.29234775164612 0.436505551101972 8.15688825351441 12.9308605436038 0.630807843453944 0.529113507937994 -46.3956016202049 47.9912310627411 -0.966751645931939 0.335203871316162 REN other 1 1 1 0.630807843453944 -0.966751645931939 0.00100260808743807 268.240490518905 90.6526333293896 2.95899281319543 0.00357766406124135 -572.71732712615 336.345354394967 -1.70276568307709 0.0906425803688 SOX13 other 1 1 1 2.95899281319543 -1.70276568307709 0.101753788476246 33.3711820143068 28.3691085442641 1.17632113685342 0.241293555417144 -159.232031338708 105.256929851329 -1.51279380429979 0.132394914977339 ETNK2 other 1 1 1 1.17632113685342 -1.51279380429979 0.0340146450432609 61.6482973042995 24.0718100412508 2.56101627582868 0.011458457972324 98.6616687882305 80.8910299073774 1.21968614939383 0.224564052734489 PPFIA4 other 1 1 1 2.56101627582868 1.21968614939383 0.678360455028319 -63.7265663609906 73.6454283695508 -0.865315984601413 0.388202691686498 -3.34844324858673 275.365306852515 -0.0121600040573744 0.990313596874673 PLEKHA6 other 1 1 1 -0.865315984601413 -0.0121600040573744 0.715783773940276 -9.27351743989924 12.3446805845118 -0.751215665436836 0.453707710590519 -22.7775811275778 45.6087233328874 -0.499412819809261 0.618225215359513 PTPN7 other 1 1 1 -0.751215665436836 -0.499412819809261 0.890287118492422 3.3630854007065 27.6111321109899 0.121801793102425 0.90322234056791 49.234756069723 102.088402992675 0.482275700534329 0.630327434858148 SYT2 other 1 1 1 0.121801793102425 0.482275700534329 8.2060145637986e-07 278.652840114823 54.2556871947808 5.13591946802636 8.71525731648579e-07 -159.602195875146 200.527641972456 -0.795911198602077 0.427358390701269 ARL8A other 0.00753886557976178 1 0.00955279354460007 5.13591946802636 -0.795911198602077 0.595146454751159 -3.53821238335541 14.5385707967268 -0.243367276799451 0.808053396053265 -47.7630311586369 46.9240675520858 -1.01787917480981 0.310374324590752 OSR1 other 1 1 1 -0.243367276799451 -1.01787917480981 0.886712617916208 1.67029716283449 6.39503842276545 0.261186415532463 0.794307016575548 -7.26392678894872 21.8256617340975 -0.332815878732351 0.739737963382778 GDF7 other 1 1 1 0.261186415532463 -0.332815878732351 4.88272514548634e-07 1879.70273014085 401.133686617654 4.68597575534091 6.08395628610585e-06 -1654.49134337895 1246.00187116654 -1.32784017557692 0.186195699553979 PDIA6 other 0.0045751134613207 1 0.0629628636049095 4.68597575534091 -1.32784017557692 0.524266813294525 254.42755173352 236.871428527761 1.07411667719858 0.284506775456292 -67.1071693402538 807.512261511286 -0.0831035917828176 0.933880710687248 RHOB other 1 1 1 1.07411667719858 -0.0831035917828176 1.53008189998272e-05 702.532852200048 185.251361661632 3.7923222042667 0.000213882218017843 -959.19331248034 582.896293591734 -1.64556426765027 0.101892985453573 ATP6V1C2 other 0.1239213330796 1 1 3.7923222042667 -1.64556426765027 1.75456305356499e-09 187.957213278903 28.6349668696246 6.56390538653929 7.6811610404313e-10 -84.7943642277774 113.03586081573 -0.75015454047816 0.454313651225231 HNRNPLL other 1.95563597950354e-05 1 9.72895857381029e-06 6.56390538653929 -0.75015454047816 0.000448351158919014 86.2033010633233 27.4031263268883 3.14574695000181 0.00199338741232796 -217.645929217584 108.031284163921 -2.01465650345635 0.0457040301866841 GALM other 1 1 1 3.14574695000181 -2.01465650345635 0.00276385216682271 31.3179530923518 9.91594804577515 3.15834178918427 0.00191209593737609 -28.2129078202891 40.4601093151646 -0.69730181894775 0.48667214357338 CAMKMT other 1 1 1 3.15834178918427 -0.69730181894775 0.00118811391108763 342.268091337929 101.917181115713 3.35829629107708 0.000991250480908406 -388.732394639987 457.553697472894 -0.84958857678779 0.396890023991482 EML4 other 1 1 1 3.35829629107708 -0.84958857678779 0.0980748097766061 13.6243646404258 6.28774127238081 2.16681381281884 0.0317764356326398 6.13856435684613 26.6124617915297 0.230665032229372 0.817879215818464 CHAC2 other 1 1 1 2.16681381281884 0.230665032229372 0.127756114400885 756.127826051148 686.207126031719 1.10189445339015 0.272215628579215 -4319.69819626899 2926.20953923644 -1.47620945743898 0.141916350272105 RPS27A essential 1 1 1 1.10189445339015 -1.47620945743898 1.02365068375004e-10 330.251978063383 45.7362988269869 7.22078494616876 2.41274669552526e-11 61.3710706537399 160.178750285996 0.383141150397059 0.702157543946428 ASXL2 other 1.2117976794233e-06 1 3.19399407553634e-07 7.22078494616876 0.383141150397059 0.00307662212044031 14.7509462140898 4.74197999753089 3.11071455842717 0.00226219409101513 -15.2168689572525 17.387484515065 -0.875162186000407 0.382984625063298 ABHD1 other 1 1 1 3.11071455842717 -0.875162186000407 4.44172087699131e-33 549.158088862832 35.89929664044 15.2971824034072 3.94212173464396e-32 -307.26831766199 183.040705685797 -1.67868844534198 0.0953518393434672 CIAO1 essential 6.45248791800528e-29 1 5.72829709261113e-28 15.2971824034072 -1.67868844534198 0.0069883562208774 4.66984386347137 14.7800485602068 0.315955921555243 0.752527560266788 -138.948529411765 46.4527515932727 -2.99117973954179 0.00330846399707099 ZNF514 other 1 1 1 0.315955921555243 -2.99117973954179 5.9670160627094e-35 3684.540234662 224.499297679212 16.4122572887816 5.80870222036092e-35 -288.908852887265 1144.6605844327 -0.252396960999972 0.801089230572812 SNRNP200 essential 8.67663805678574e-31 1 8.449338249737e-31 16.4122572887816 -0.252396960999972 0.00479779617320999 44.5549201161948 34.5630869515902 1.28908972102519 0.19958776748177 -283.94362745098 108.62958169039 -2.61387020950023 0.00997629807938695 MRPS5 essential 1 1 1 1.28908972102519 -2.61387020950023 0.116110098398209 63.2260626891832 36.2515444305504 1.74409293955213 0.0831253160034243 -50.3940169930821 99.2693505132118 -0.507649306987006 0.61242089838286 ST6GAL2 other 1 1 1 1.74409293955213 -0.507649306987006 6.77296656413855e-06 67.556922499403 21.1294244368034 3.19729118516507 0.00168586881148536 -153.296641982049 58.746483179292 -2.60946074872591 0.00996884581883101 NPHP1 other 0.0568184165065583 1 1 3.19729118516507 -2.60946074872591 0.799161571779742 -25.8087994403303 50.7988194471822 -0.508059039977589 0.612143634881331 -82.5397996792135 141.236785749061 -0.58440723669444 0.559807082530711 MALL other 1 1 1 -0.508059039977589 -0.58440723669444 0.0130273172478025 5.65901036806348 52.3306659484865 0.10813946785302 0.914024918627259 -367.647336993547 137.962559107558 -2.66483413595513 0.00851801730097624 RALB other 1 1 1 0.10813946785302 -2.66483413595513 3.22763009087671e-06 56.9107411034935 16.3653101523009 3.47752291730884 0.000656924816973474 -94.9647938740984 43.6526764574406 -2.1754632609225 0.0311105713359029 TMEM177 other 0.0279900081480828 1 1 3.47752291730884 -2.1754632609225 0.000218359014717219 3.71558425009558 1.39058840989318 2.67195111340027 0.00835272402506252 -8.6338455167141 3.97955594752708 -2.16954997757457 0.0315744262734794 NT5DC4 other 1 1 1 2.67195111340027 -2.16954997757457 2.17575510619311e-14 165.295095404064 20.7928136052745 7.94962618056333 3.82283432522026e-13 -141.444222097511 85.4387397107993 -1.65550454719117 0.099871898122779 RABL2A other 2.88570399734393e-10 1 5.22084483795331e-09 7.94962618056333 -1.65550454719117 0.138065031842709 52.094530828391 47.0643749359514 1.10687820457161 0.270072560636531 -160.5158800839 134.722359736952 -1.19145686282003 0.23530727265275 SLC20A1 other 1 1 1 1.10687820457161 -1.19145686282003 0.369311843870017 17.7081729699214 20.5034405006442 0.863668366748741 0.389104589412176 -43.7991797716824 57.9130635952486 -0.756291880495092 0.450622144781171 FBLN7 other 1 1 1 0.863668366748741 -0.756291880495092 2.55182262755307e-10 82.2296015025756 14.6978464565477 5.59467005902374 9.76761179740501e-08 -93.5730985739646 41.5148529108811 -2.25396676160302 0.025600111288606 ZC3H8 essential 2.9667489867932e-06 1 0.00113577789980225 5.59467005902374 -2.25396676160302 2.49775234756192e-16 39.4141905881037 4.59826702657615 8.57153148355791 1.15959249536104e-14 -50.1929662581836 21.3244537234152 -2.35377500916094 0.0198806526096771 LIPT1 other 3.41942296381226e-12 1 1.6113697315537e-10 8.57153148355791 -2.35377500916094 1.32388856973601e-13 92.9705820002283 11.0369083169822 8.42360734818976 2.93563327929428e-14 29.1037783539617 55.2886807913689 0.526396686218368 0.599400599457882 FAHD2B other 1.7221142515126e-09 1 4.06027438859191e-10 8.42360734818976 0.526396686218368 9.52323503037198e-10 9.53212027072007 1.43022293858949 6.6647793246281 4.66637251998647e-10 -2.35991530751877 6.63313759877413 -0.355776624919542 0.722504396674175 LYG1 other 1.07612555843203e-05 1 5.94915832573076e-06 6.6647793246281 -0.355776624919542 0.397706393237407 10.8138580194015 10.5291232034154 1.02704259514161 0.306032029395187 -29.465271312515 46.677254059738 -0.631255456347219 0.528821627456106 AFF3 og 1 1 1 1.02704259514161 -0.631255456347219 2.87684458316819e-08 466.23910953332 127.26680592122 3.66347773214272 0.00034104059513982 -1075.89693281351 317.367962429754 -3.3900615694681 0.000886430896721052 UBXN4 other 0.000297839719695403 1 1 3.66347773214272 -3.3900615694681 3.62221496672593e-06 83.0880828042232 21.3714189279644 3.88781311546435 0.000150003049107988 -124.768481296415 55.1575763263673 -2.26203705105097 0.0250942377643916 SPOPL other 0.0312597151628448 1 1 3.88781311546435 -2.26203705105097 0.332632743087304 12.2133922001472 8.27781947763767 1.47543592043066 0.142150332343367 13.5184367590549 21.5264854344313 0.627990890581347 0.530946138729373 THSD7B other 1 1 1 1.47543592043066 0.627990890581347 8.84597747880894e-06 13.7523875501015 3.04047708564344 4.52310185629671 1.2252831996331e-05 -0.6979728503802 7.29436616549988 -0.0956865661174782 0.923896380735257 GPR17 other 0.0734746889389871 1 0.123435029531039 4.52310185629671 -0.0956865661174782 4.63505870890616e-05 168.173032393497 47.5510616545626 3.53668302119519 0.000535624645773888 -138.972371116399 114.354873664091 -1.21527283152461 0.226121899370919 POLR2D essential 0.354211186534609 1 1 3.53668302119519 -1.21527283152461 1.23022965910188e-11 149.013925277825 23.7325088716439 6.27889474660094 3.31346151298575e-09 -81.832715055271 57.0739739411969 -1.43380089740348 0.153656372113689 AMMECR1L other 1.50752342426345e-07 1 4.10703554534584e-05 6.27889474660094 -1.43380089740348 1.27321506817408e-05 50.3310515706366 10.8147536797027 4.65392491232591 6.91222678236853e-06 -5.29302452544933 33.3593697260557 -0.158666802428079 0.874136612794141 GALNT13 other 0.104059867521868 1 0.0711337258173545 4.65392491232591 -0.158666802428079 8.0040954533916e-13 687.189153766829 100.637946745255 6.82833042596062 1.89754047947805e-10 -836.523242751222 324.922469009903 -2.57453184231998 0.0109861091233239 PKP4 other 1.01916147408035e-08 1 2.45238131567744e-06 6.82833042596062 -2.57453184231998 0.0494850687999665 20.4254524819307 18.2836545871602 1.117142767304 0.265673150506268 -109.752404276925 62.1682934407881 -1.76540802718765 0.0794771197761924 SCRN3 other 1 1 1 1.117142767304 -1.76540802718765 0.32134348372619 21.4608620596641 26.6855225848503 0.80421367021861 0.422546310668294 -98.0025354696021 95.266496562226 -1.0287198438707 0.305267301004285 LNPK other 1 1 1 0.80421367021861 -1.0287198438707 0.646518488644855 -1.81252237402684 2.64104753745823 -0.686289189543036 0.493549534961992 3.8497212835512 9.21529608908092 0.417753401121064 0.676701850791385 ZNF385B other 1 1 1 -0.686289189543036 0.417753401121064 0.885873174428949 16.5459083494441 56.0171480789405 0.295372201493144 0.768107427668595 -54.1111950217497 189.372524146696 -0.285739418986848 0.775461690005618 CDCA7 other 1 1 1 0.295372201493144 -0.285739418986848 0.404088330289689 47.9227109634552 36.7576035857687 1.30374959977014 0.19425197802276 1.26580730897012 115.796928340625 0.0109312684464881 0.991292340341439 DLX1 other 1 1 1 1.30374959977014 0.0109312684464881 1.55670406572272e-07 162.700482955081 34.5680313490754 4.70667482657884 5.54226555039658e-06 -216.381751466787 106.857689169386 -2.02495256212951 0.0445887170037018 UBR3 other 0.00152463596196884 1 0.0575398009442173 4.70667482657884 -2.02495256212951 0.0011034381864557 14.7096832458106 5.68976216162646 2.58528965323319 0.0106758909063847 -32.4843228417568 17.3359344790934 -1.87381435254799 0.0628882817461398 PHOSPHO2 other 1 1 1 2.58528965323319 -1.87381435254799 0.840290033465817 6.47910302242444 30.1891571343061 0.21461689021658 0.830348123665083 -44.3578729281769 98.910953060183 -0.44846269857684 0.654445584695402 GULP1 other 1 1 1 0.21461689021658 -0.44846269857684 0.747658376169407 20.1448407948288 26.4363864847245 0.762011888669766 0.447188903945704 25.760183316803 88.454645139217 0.291224765825012 0.771261384302134 FAM171B other 1 1 1 0.762011888669766 0.291224765825012 3.43009835845928e-05 838.758628831982 279.148770612723 3.0047011383605 0.00312303053272847 -2383.53129503724 963.491258400118 -2.47384838653867 0.014496754144307 HSPD1 essential 0.266964555238886 1 1 3.0047011383605 -2.47384838653867 2.73021111656172e-05 16.0261224489796 4.30820867158851 3.7199039486336 0.000278719814681787 -23.8367346938775 14.8691034709066 -1.60310503861361 0.110960516903352 CCDC150 other 0.215468261319051 1 1 3.7199039486336 -1.60310503861361 2.43706249195958e-13 143.584092235844 20.657963091797 6.95054452357208 9.50736055423091e-11 -97.0384705195562 59.2479316403113 -1.63783726845804 0.103484143797009 METTL21A other 3.14868473961177e-09 1 1.23975981627171e-06 6.95054452357208 -1.63783726845804 3.00022207772646e-08 187.199859769896 32.0471137152431 5.84139531045676 3.03681583698154e-08 22.9792416950849 93.2652850915685 0.246385798022531 0.805716019999233 PTH2R other 0.000310162958395362 1 0.00036192771145146 5.84139531045676 0.246385798022531 0.103710767274582 -769.24576113489 470.8346517658 -1.63379173187432 0.104332144418749 -2638.03053132218 1393.87180746477 -1.89259192789066 0.0602764785915732 NBEAL1 other 1 1 1 -1.63379173187432 -1.89259192789066 2.36003178603903e-11 107.023176579456 17.7038929968538 6.04517755492961 1.09481459266342e-08 -104.289265584252 51.1659568144576 -2.03825496633307 0.0432466170380815 KANSL1L other 2.86295455964394e-07 1 0.000133030921154532 6.04517755492961 -2.03825496633307 0.00445910853639901 71.8742256935092 26.3764974069973 2.72493442114274 0.00719108106637237 -41.707342751512 71.4010551798156 -0.584127820611008 0.560005942943156 SPAG16 other 1 1 1 2.72493442114274 -0.584127820611008 0.79892331767494 -0.95526579739218 6.2254903354248 -0.153444266382753 0.878250133406151 -10.6623035773989 16.256910306003 -0.655862853193064 0.51289743021237 ABCA12 other 1 1 1 -0.153444266382753 -0.655862853193064 1.23426995680022e-06 316.703354979438 75.2060991104396 4.21113923904445 4.33527039601238e-05 -155.265672746921 142.821831291138 -1.0871284266788 0.278700958662858 SUMF1 other 0.0111689088390851 1 0.412544330884538 4.21113923904445 -1.0871284266788 3.20205966722126e-12 179.843410326087 29.9504977272709 6.00468853518698 1.29723809189232e-08 -115.247792119565 68.984508225099 -1.67063294476939 0.0967992779565837 RHBDD1 other 4.00257458402658e-08 1 0.000157095532928159 6.00468853518698 -1.67063294476939 0.0160545273916044 182.465622872702 62.898726072577 2.90094305983495 0.0042513452587812 154.714804369672 138.932331070242 1.11359827606614 0.267142806459045 ACKR3 other 1 1 1 2.90094305983495 1.11359827606614 0.183644044899471 -1.1561570493754 15.3376938915193 -0.0753801097839534 0.940007642655299 54.8007903458826 34.1621016158581 1.60413990222557 0.110680279612264 TRPM8 other 1 1 1 -0.0753801097839534 1.60413990222557 0.996100172373968 -2.32066920831301 61.2952007231009 -0.0378605368925466 0.969851314054884 7.09713665070559 134.908380645839 0.0526070850211816 0.958117880566518 HES6 other 1 1 1 -0.0378605368925466 0.0526070850211816 0.000104014996321693 102.773807075766 25.0267292035995 4.1065616781031 6.79610560328798e-05 33.470200225883 57.0535336836601 0.586645525086359 0.558386557151999 ESPNL other 0.761077728085831 1 0.632989275890243 4.1065616781031 0.586645525086359 0.000453023415916328 46.2690355329949 33.4209656818204 1.38443143664647 0.168382925981864 -199.695775391375 73.0423834220362 -2.73397123746004 0.00704884698964077 ANKMY1 other 1 1 1 1.38443143664647 -2.73397123746004 1.04272611274131e-09 262.192172111785 50.9878961105659 5.14224339720211 8.08636517571774e-07 -201.646573027583 112.849034912854 -1.78687015961901 0.0759128862208116 COPS7B other 1.1761950551722e-05 1 0.0088812548724908 5.14224339720211 -1.78687015961901 3.17617140851964e-09 140.930087772098 27.653403733487 5.09630167520528 9.89799480799398e-07 -96.3276450665251 61.1825469045365 -1.57443012656576 0.117413915038852 DIS3L2 other 3.49092999510394e-05 1 0.0108194981246182 5.09630167520528 -1.57443012656576 3.5330553920343e-05 79.8431049626705 35.7322454370556 2.23448327934831 0.0268632334239248 -189.164855072464 74.1070062791454 -2.55259070053268 0.0116464525093509 FANCD2 other 0.274412412299304 1 1 2.23448327934831 -2.55259070053268 3.54420834917345e-08 21.9506709608159 8.8185935587692 2.48913512279837 0.0138414133087084 -63.5046162104133 17.1348723762413 -3.70616219461704 0.000290642564425172 TAMM41 essential 0.000364309176211539 1 1 2.48913512279837 -3.70616219461704 1.778633210818e-09 782.192109500807 164.977770601235 4.74119699066264 4.71095068895361e-06 -601.284380032207 320.558264232275 -1.87574131483479 0.0625355829364632 VGLL4 other 1.98175312349341e-05 1 0.0492294346995652 4.74119699066264 -1.87574131483479 1.50293896231303e-10 209.314400496763 51.5347260032426 4.06161857702694 7.67429243654563e-05 -359.530633749812 103.159038683117 -3.48520729098897 0.00063764568940435 RAB5A other 1.76595328071781e-06 1 0.71056273669976 4.06161857702694 -3.48520729098897 1.99904321712332e-11 801.345079113376 124.362012452412 6.44364837228745 1.77800073013793e-09 -340.196452824987 310.702965022792 -1.09492502847545 0.2754431103793 RETREG2 other 2.43103645634366e-07 1 2.22605691413269e-05 6.44364837228745 -1.09492502847545 1.60371273800556e-05 385.864303448276 151.781136153157 2.54224150133462 0.0120568707742628 -1102.86512 392.269965557368 -2.81149518656868 0.00560920506367214 CTDSP1 other 0.129638652429142 1 1 2.54224150133462 -2.81149518656868 0.00142748712420024 179.000444389997 63.0279007727758 2.84001913748195 0.00514649583507197 -185.628785422087 166.227557588757 -1.11671487035457 0.265925931729716 CNOT9 other 1 1 1 2.84001913748195 -1.11671487035457 7.37894802908019e-13 183.541469893742 24.0842002697375 7.62082476636635 2.71735894639454e-12 12.1867473435655 59.4336569601376 0.205047913369006 0.837814541828486 STK11IP other 9.4044692630627e-09 1 3.66517374689696e-08 7.62082476636635 0.205047913369006 0.000350326771129584 186.835716422375 52.4412167918269 3.5627647078451 0.000496112226521362 -56.0934310499549 130.332769099932 -0.430386244666876 0.667549343035862 GMPPA other 1 1 1 3.5627647078451 -0.430386244666876 0.101031004882216 6.11343379686639 5.71998028446197 1.06878581618073 0.286806718934765 -12.0567724395543 10.8885249659201 -1.10729161913947 0.26986146564715 GRIP2 other 1 1 1 1.06878581618073 -1.10729161913947 4.90799243808564e-10 142.561582804104 28.8819626715982 4.93600744606928 2.04006414092701e-06 -105.664502198339 55.3173158068922 -1.91015237556364 0.0579603437949177 EAF1 other 5.62848572799661e-06 1 0.0218715276548784 4.93600744606928 -1.91015237556364 0.327322579789447 8.72160690820363 22.4654828916187 0.388222543458322 0.69841684221587 -46.8133408422501 43.1099869729746 -1.08590477820365 0.279310801626304 CNTN4 other 1 1 1 0.388222543458322 -1.08590477820365 3.34045488920657e-05 69.6253384137171 34.9891754053465 1.98991081118985 0.0483710536794574 -226.473762492062 77.1258031388705 -2.93642015090955 0.00382990876442888 DYNC1LI1 other 0.260321649515868 1 1 1.98991081118985 -2.93642015090955 0.735242522892713 -8.48849435320811 15.1834873496172 -0.559060916491107 0.576916729817739 -25.1668228370404 33.642855474859 -0.748058465365619 0.455543969128053 RBMS3 other 1 1 1 -0.559060916491107 -0.748058465365619 8.28187722662673e-11 575.932504325903 81.1367220405931 7.09829642905418 4.26156568705409e-11 252.875751449963 178.911258117807 1.41341441623227 0.159539043608119 OSBPL10 other 9.8380419575099e-07 1 5.609925070438e-07 7.09829642905418 1.41341441623227 6.99298290998071e-11 185.45858917374 32.9746208309077 5.62428269076276 8.47307110832774e-08 -151.552129860062 72.6564036694851 -2.08587436490078 0.038628318391067 POMGNT2 other 8.33493633040601e-07 1 0.000987790629808848 5.62428269076276 -2.08587436490078 0.891791577722812 -7.11993021056403 58.9783511087084 -0.12072107945915 0.904068310612692 -61.4292322074986 130.140429341052 -0.472022664429011 0.637574448608281 ACKR2 other 1 1 1 -0.12072107945915 -0.472022664429011 0.000745741826137732 32.1428703391765 9.94744396602526 3.23126930384911 0.00150530948370829 -14.335937924514 21.9182354811999 -0.654064417585552 0.514039547877083 FAM198A other 1 1 1 3.23126930384911 -0.654064417585552 0.0529309448796063 85.4791523855794 58.8961713523242 1.45135329551785 0.148689509929068 -147.018215457516 128.043902685987 -1.14818599225347 0.252649412396389 CSRNP1 other 1 1 1 1.45135329551785 -1.14818599225347 8.66649845061061e-05 401.005617042801 125.784120121335 3.18804644541759 0.00173101562903321 -390.840343544727 273.46242151992 -1.42922870854582 0.15493793405093 SLC25A38 other 0.640714230453642 1 1 3.18804644541759 -1.42922870854582 0.160392016925305 108.569099305761 70.7502486399475 1.53454018032186 0.126935490217293 -54.8937989398057 154.979904638877 -0.354199462618816 0.723670791536143 ITGA9 other 1 1 1 1.53454018032186 -0.354199462618816 2.29116510854306e-09 470.199713362718 78.0895817447851 6.02128610317622 1.19375978804913e-08 -3.52401584818218 170.912687789767 -0.0206188077301607 0.983576086022049 GOLGA4 other 2.53563242562461e-05 1 0.000144874687877643 6.02128610317622 -0.0206188077301607 0.000111333295269101 134.462385302586 80.6830020252153 1.66655158989453 0.0976230995839304 -511.691588407825 176.737809410128 -2.89520159899924 0.00433656809070673 CTDSPL other 0.81239905557863 1 1 1.66655158989453 -2.89520159899924 0.0627791713347613 -10.8805126605313 11.4152846538767 -0.953152986582444 0.341996604888747 -59.5221944921055 25.0787289867707 -2.37341352201318 0.0188499906745708 STAC other 1 1 1 -0.953152986582444 -2.37341352201318 1.13149317910403e-05 258.293667336188 59.401870972127 4.34824127774336 2.47574087276549e-05 6.62227612081696 116.433382240886 0.056876095097163 0.954717149652793 IQSEC1 other 0.093008739322351 1 0.241739903652296 4.34824127774336 0.056876095097163 6.82542337735035e-07 114.64688257152 24.6256852046404 4.65558142316854 6.86362623711032e-06 -19.1312293759522 48.3033638348716 -0.39606412177325 0.692598906810796 CAND2 other 0.00631556425106228 1 0.0706610321110507 4.65558142316854 -0.39606412177325 0.0540267124135539 1600.710533466 2183.93308605542 0.732948524699159 0.464689743546847 -7140.114850064 4283.79204761661 -1.66677438369973 0.097565755012086 RPL32 essential 1 1 1 0.732948524699159 -1.66677438369973 1.53294804747214e-05 629.291591087778 141.537457047429 4.44611344738872 1.70552717813526e-05 154.175735101413 331.684272442311 0.464826788337481 0.642738635516499 PTPRG other 0.12412280340382 1 0.16934179351705 4.44611344738872 0.464826788337481 2.89068525115167e-08 836.049549655479 140.626189381376 5.94519095862099 1.78255806561081e-08 405.683818168991 319.595137366673 1.26936793066269 0.206224841494857 IL17RD other 0.000299185923494198 1 0.000214566514357573 5.94519095862099 1.26936793066269 2.16674121973318e-10 73.5806829554053 19.527676995098 3.76802028084939 0.000233852993904394 -156.690617517902 46.5492756644679 -3.36612364599063 0.000962630026648343 SHQ1 essential 2.52685361045284e-06 1 1 3.76802028084939 -3.36612364599063 0.00383125704770301 288.964054867518 112.129333768783 2.57706030309053 0.0109222051320424 -178.003418005983 267.0214560489 -0.666625898307531 0.506028408808725 SLC25A26 essential 1 1 1 2.57706030309053 -0.666625898307531 1.45339785913014e-08 111.473066274139 49.0667105267748 2.27186752642222 0.0244882305938686 -462.724862439982 115.600032965071 -4.00280908725863 9.72915477639575e-05 UBA3 essential 0.000153493347902734 1 1 2.27186752642222 -4.00280908725863 0.00634683931858629 -200.073853082395 166.906475681354 -1.19871833771365 0.232490840485558 -1257.81339151158 393.227788936852 -3.19868897086918 0.00167823223325108 ARL6IP5 other 1 1 1 -1.19871833771365 -3.19868897086918 1.78037538612236e-10 196.42524445379 40.3137507371672 4.87241303183174 2.72904458732528e-06 -204.034328672064 94.9782625354341 -2.14822132165183 0.033270048568192 TMF1 other 2.08392938945622e-06 1 0.0289960987403311 4.87241303183174 -2.14822132165183 0.025589246144673 1234.33174207958 523.792116433438 2.35652982042627 0.0197479409611378 -89.6910923354375 1245.50110246133 -0.0720120537494446 0.942688887076969 LRIG1 other 1 1 1 2.35652982042627 -0.0720120537494446 2.15204267865418e-06 117.297786124093 38.9306767884914 3.01299118844932 0.00302233309081164 -244.880080829142 85.9036391582655 -2.85063686740889 0.00495748570776422 LIMD1 other 0.0190391215780535 1 1 3.01299118844932 -2.85063686740889 1.36459417629665e-08 59.8044661441884 10.7732176051158 5.55121676144268 1.21240928153791e-07 -14.697581479305 23.7554549204938 -0.618703431632681 0.537025828390776 ZNF660 other 0.000144346771968659 1 0.00140287877966752 5.55121676144268 -0.618703431632681 0.767882845499371 -29.2422580698314 40.2331781496131 -0.726819491144589 0.468454411191226 -21.6313137471369 178.061343434661 -0.121482368547188 0.903469430602463 NFKBIZ other 1 1 1 -0.726819491144589 -0.121482368547188 0.00146284463451181 -214.448228882834 120.907718938581 -1.77365209405505 0.0781100093804686 1462.81133139152 530.309822315821 2.75840889577255 0.00651680016952873 COL8A1 other 1 1 1 -1.77365209405505 2.75840889577255 5.20348146957203e-05 38.7596437823835 8.54154974562059 4.53777650856114 1.13810226183859e-05 10.4007707253887 37.8441137924197 0.274831927164112 0.783813727805715 NXPE3 other 0.39551662650217 1 0.114971090490934 4.53777650856114 0.274831927164112 0.115678442346073 16.0600453448403 37.7766686729138 0.425131328648774 0.67133825604488 -283.51203101002 144.477610670134 -1.96232502527554 0.051538777746451 SRPRB essential 1 1 1 0.425131328648774 -1.96232502527554 0.260714483285316 35.0699775792331 25.0628417882801 1.39928176842391 0.16377937204318 -69.7342068794575 101.926011330573 -0.684164973877876 0.494919653693669 TMEM108 other 1 1 1 1.39928176842391 -0.684164973877876 0.158588405213043 -2.21243730132394 1.16276521022256 -1.90273778564502 0.0589656769000347 0.795848782575662 4.6521216370817 0.171072221377879 0.86439449867659 AGTR1 other 1 1 1 -1.90273778564502 0.171072221377879 3.02030832218918e-05 42.9045022725091 9.43630551199316 4.5467479002221 1.10081071621544e-05 -35.1276501702564 39.4880632852122 -0.889576425071506 0.375089932661865 MED12L other 0.236641157043522 1 0.111353099652472 4.5467479002221 -0.889576425071506 9.52070340769096e-06 323.262436451965 66.7316727120401 4.8442129998285 3.08720572433266e-06 -235.438817803383 274.277056397457 -0.858397785421052 0.392015616602203 EIF2A other 0.0788028621054581 1 0.0326780725920612 4.8442129998285 -0.858397785421052 0.109729776795146 31.0282301374618 14.6594206649489 2.11660684597524 0.0359006681992395 17.3416204663071 60.3872358895671 0.287173608972938 0.774365433351959 ALDH1L1 other 1 1 1 2.11660684597524 0.287173608972938 8.32824549169548e-05 93.9734674878259 21.6843259515412 4.33370480123901 2.64473056902414e-05 -32.0671341691823 89.0339677714009 -0.360167416682094 0.71921864538196 OSBPL11 other 0.617206273389552 1 0.257834783174163 4.33370480123901 -0.360167416682094 0.0975188454391229 11.7619330169991 5.43154896287017 2.16548411832485 0.0318898752033166 12.0689565577924 22.5119138785554 0.536114193706524 0.592653149306881 TRPC1 other 1 1 1 2.16548411832485 0.536114193706524 5.05944996001368e-05 163.085457479355 36.7710717602088 4.43515648776479 1.77657381206701e-05 248.53597844579 199.732144362049 1.24434641824741 0.215325937324577 NCEH1 other 0.384922952957841 1 0.175987401823358 4.43515648776479 1.24434641824741 1.36206076166452e-08 30.4473154293464 7.17781867139256 4.2418618835685 3.85012760650264e-05 -3.31867846795573 13.9783936187787 -0.237414867434938 0.812656773081765 FAM86B2 other 0.00014409240797649 1 0.368264705561977 4.2418618835685 -0.237414867434938 9.55869371445776e-08 543.17411243811 90.8875622551149 5.97633052268977 1.59565608437574e-08 221.348076008815 363.353093804157 0.6091817567628 0.543325525028787 LPP other 0.000952428241708572 1 0.000192452080336558 5.97633052268977 0.6091817567628 2.97637564746213e-16 93.7538098762262 9.83810916532943 9.52965740679366 3.13575665503031e-17 58.9696663620779 36.6420707503831 1.60934317178189 0.109576137182932 TMEM44 other 4.07049133546921e-12 1 4.43897712086091e-13 9.52965740679366 1.60934317178189 6.94276516366624e-07 115.235283822414 24.9318708839443 4.62200708317577 9.15239704260746e-06 -51.9729712385507 53.9197057893315 -0.963895675573847 0.336915732421669 AMT other 0.0064192806703258 1 0.0932263162759996 4.62200708317577 -0.963895675573847 0.0474030255458529 65.487223615892 69.8527350089626 0.937504073498189 0.350264896676928 -257.157307041595 151.069245376564 -1.70224790890158 0.0911363326568784 TCTA other 1 1 1 0.937504073498189 -1.70224790890158 1.84039902317929e-09 139.41709935243 25.8389259677281 5.39562284928395 3.19027455629525e-07 -88.1220698909047 55.8813773975313 -1.57694877962685 0.117275610587542 NICN1 other 2.04854815270087e-05 1 0.00359543942494475 5.39562284928395 -1.57694877962685 7.56709651095398e-18 523.289140659712 61.5378152640482 8.50353783952791 2.812372708233e-14 -248.734675430129 142.145679586419 -1.74985744310933 0.0823819086608315 DCAF1 other 1.05303715046436e-13 1 3.89091764184036e-10 8.50353783952791 -1.74985744310933 0.0482178849578708 -5.29758585827651 81.9730154240763 -0.0646259727163892 0.948566008531009 -432.957548277727 188.72462479893 -2.29412324300025 0.0233043935325662 MANF other 1 1 1 -0.0646259727163892 -2.29412324300025 0.137531961294785 2.54788786258844 2.04785154172317 1.24417605997187 0.215428507226587 -9.70133063409848 7.61703088171407 -1.27363677327187 0.204816091390052 TM4SF19 other 1 1 1 1.24417605997187 -1.27363677327187 0.0511422647767094 369.039768279319 258.182989124438 1.42937290148674 0.154962675349251 2212.14409477585 974.267801787527 2.2705708745759 0.0245872580440202 MUC4 other 1 1 1 1.42937290148674 2.2705708745759 0.00434339308282967 141.232003504554 75.8220621762836 1.86267689707772 0.0644635302178971 -146.018093278184 138.382706347647 -1.05517587516576 0.29304147567389 SLIT2 other 1 1 1 1.86267689707772 -1.05517587516576 1.1159838279509e-08 203.381899820395 31.5468126055943 6.44698728721419 1.77743798122365e-09 7.01162642187196 133.294149671415 0.0526026568994694 0.958124569408349 EIF2B5 essential 0.000118606761234622 1 2.22553009629013e-05 6.44698728721419 0.0526026568994694 0.0542749747764797 80.5809139784947 33.8274492269597 2.38211617547189 0.0187211454403783 -34.0577572964671 138.886884036666 -0.245219392260798 0.806688694158347 ECE2 other 1 1 1 2.38211617547189 -0.245219392260798 0.703209677843266 -2.48745480538444 4.06846635154769 -0.611398642743645 0.541995229281417 -10.8982175724535 16.9804214605843 -0.641810781773049 0.522117511070328 VWA5B2 other 1 1 1 -0.611398642743645 -0.641810781773049 3.92963514761852e-05 119.539781920507 35.1270277257229 3.40307135730045 0.000886154277377167 -42.6506858951811 63.7064904656486 -0.669487293734678 0.504372001985019 DGKQ other 0.302778388124007 1 1 3.40307135730045 -0.669487293734678 1.13217993298856e-14 231.950222313078 37.8881060236155 6.12197986799615 9.1625926297254e-09 -106.329176675014 64.3269945427141 -1.65294799533049 0.100631296742107 FIP1L1 essential 1.50840332472066e-10 1 0.000111701166748982 6.12197986799615 -1.65294799533049 5.65718179105414e-06 91.612275765037 20.6351540751486 4.43962160066291 1.90486283673817e-05 15.8015124868098 37.4239818014261 0.422229589856408 0.673554927235471 SLC26A1 other 0.0478314720433628 1 0.188181399641364 4.43962160066291 0.422229589856408 1.06819306412702e-07 156.283290150713 37.4956778270231 4.16803480314949 5.15595316669695e-05 -76.7139364303179 70.5688770070213 -1.08707888922032 0.278734154640661 LYAR other 0.00106071571267813 1 0.487237574252862 4.16803480314949 -1.08707888922032 1.29131757747562e-23 110.415281276238 11.9850195947934 9.21277436410748 2.53522227133445e-16 -53.9068592676364 24.2501207063231 -2.22295220384534 0.0277046752176685 CENPC essential 1.85252419664653e-19 1 3.56933943581178e-12 9.21277436410748 -2.22295220384534 0.023700643947828 -8.75941903183661 6.71338852187913 -1.30476867282288 0.193930716549055 -34.9043673444336 12.6358768675906 -2.76232252895395 0.00644291438031284 CORIN other 1 1 1 -1.30476867282288 -2.76232252895395 0.0343982540398696 9.8096947856661 17.3456970842244 0.565540533657068 0.572534582987219 -60.9160726341724 32.6479082544496 -1.86584917353381 0.0639769299318211 ATP10D other 1 1 1 0.565540533657068 -1.86584917353381 0.000324189425282254 -69.640751970891 116.364130795717 -0.598472669324098 0.550464798236425 -832.147290256308 220.662773216453 -3.77112676563724 0.000236592437936264 OCIAD2 other 1 1 1 -0.598472669324098 -3.77112676563724 1.43680325430729e-06 19.683722362927 3.99801608658139 4.92337247691218 2.2861527636435e-06 4.99997555323039 7.5690474353861 0.660581875845431 0.509928592332255 SLC10A4 other 0.0129226084692398 1 0.0244115392101853 4.92337247691218 0.660581875845431 0.0527776031018369 486.829236649252 199.478286478595 2.4405124249024 0.0158157592108922 401.410620989515 304.490606908018 1.31830214752988 0.189385615831274 SCD5 other 1 1 1 2.4405124249024 1.31830214752988 0.27169105362171 -13.0548793067877 8.17493257448413 -1.59694030352434 0.112355911650041 -14.9368681658758 12.51945309689 -1.19309270543027 0.234692052923329 PLAC8 other 1 1 1 -1.59694030352434 -1.19309270543027 1.51195824033428e-12 225.03248415602 45.1361961333614 4.98563245097413 1.6652846485614e-06 -140.255308205744 69.1235658906095 -2.02905197957673 0.0441982832235382 ENOPH1 other 1.90930086589413e-08 1 0.0179451073728976 4.98563245097413 -2.02905197957673 5.71888656260235e-13 51.6539475855869 12.5772737546948 4.10692719209563 6.45234588463893e-05 -45.7631273066942 18.9648012636134 -2.41305599096876 0.0169788289442898 TRMT10A other 7.3144559135684e-09 1 0.602907199460661 4.10692719209563 -2.41305599096876 2.33449189415765e-12 143.150771059464 25.2693031559037 5.66500667534313 6.96308795951185e-08 -23.7684256623602 38.0228861363532 -0.625108403847216 0.532819114119747 KLHL8 other 2.93118802230435e-08 1 0.000815725754456813 5.66500667534313 -0.625108403847216 0.00108407441553785 -14.1397496087637 22.1380385805834 -0.638708328079492 0.52395534939258 -106.598500260824 33.0828831939725 -3.22216475619168 0.00155083102395485 SNCA other 1 1 1 -0.638708328079492 -3.22216475619168 8.59208831293065e-11 177.572453703704 112.901156743759 1.5728134133003 0.117787992800406 -734.123302469134 168.882465843882 -4.34694803158412 2.48006319182546e-05 PYURF other 1.02022456627739e-06 0.358716340065635 1 1.5728134133003 -4.34694803158412 1.37704114548683e-16 285.061851355876 38.3651540284175 7.4302282520416 6.53889484169003e-12 18.6872614663543 57.3844085493757 0.325650502266222 0.745122408321117 TBCK other 1.89012667629522e-12 1 8.75361852457045e-08 7.4302282520416 0.325650502266222 2.93502199898535e-06 59.4279906101014 45.6835340419548 1.30086237539162 0.195248675058874 -207.044045400644 69.474028711283 -2.9801646635618 0.00334898789415005 CAMK2D other 0.0255581715671644 1 1 1.30086237539162 -2.9801646635618 9.63738049946059e-11 90.4775334608025 57.4577507467815 1.57467934760517 0.117343442969081 -345.371892925431 84.7785818485281 -4.07381068891313 7.31978848362169e-05 CISD2 other 1.14183684157609e-06 1 1 1.57467934760517 -4.07381068891313 0.0809517475636707 -42.4226814939153 73.8255640514641 -0.574634031435808 0.566366577316121 -215.657154846832 108.563748899 -1.98645640956507 0.0487342378498738 DDIT4L other 1 1 1 -0.574634031435808 -1.98645640956507 0.000746850767085546 202.549067004687 54.1360519559718 3.74148205653079 0.000259336113691512 131.647377885211 81.7487629025806 1.61038984824876 0.109401254800551 ANK2 other 1 1 1 3.74148205653079 1.61038984824876 1.07272388807748e-08 81.8882149046795 26.7129236826613 3.06549054223634 0.00256694691600629 -91.2340925971768 40.4040421829937 -2.25804369236051 0.0253479521471573 TIFA other 0.000114137821691444 1 1 3.06549054223634 -2.25804369236051 7.99408311099458e-19 96.067687348912 11.3344440415623 8.47572999581111 1.60055164051593e-14 10.8617420427075 17.0581460791712 0.636748096322742 0.525216257172317 SPATA5 other 1.1212500971481e-14 1 2.221245566708e-10 8.47572999581111 0.636748096322742 1.1361311565033e-05 386.593829247676 94.0344659141316 4.11119290665932 6.30995229480509e-05 71.5097210481828 141.666350040129 0.504775629695597 0.614419728780494 CCNA2 essential 0.0933786197530064 1 0.590359136701964 4.11119290665932 0.504775629695597 3.30525891329886e-18 139.568701917035 18.0493750137531 7.73260579996193 1.278832256871e-12 -4.41133885312961 26.8101530861885 -0.164539860662047 0.869521939931621 METTL14 essential 4.61810775366117e-14 1 1.73332924096295e-08 7.73260579996193 -0.164539860662047 0.378017227316947 0.54660827818313 330.390819379327 0.00165442937915161 0.998682098121087 -521.236620965731 492.068245084281 -1.05927709453483 0.291132208275951 USP53 other 1 1 1 0.00165442937915161 -1.05927709453483 0.0382077899447627 115.479885895815 73.4578419214002 1.57205660927771 0.11798971229408 -63.5135336639763 116.12401413497 -0.546945729848394 0.585207688271701 SETD7 other 1 1 1 1.57205660927771 -0.546945729848394 5.39410554161058e-18 127.320006247072 18.9250960258873 6.72757517705131 3.09230047025296e-10 -43.218009787079 28.6079160091462 -1.5107010861351 0.132887564825686 NAF1 essential 7.51830430389682e-14 1 3.9643292028643e-06 6.72757517705131 -1.5107010861351 0.103231176584636 35.7675547144175 24.6715826810893 1.44974707041528 0.149136498608229 -9.59448731013735 37.50983858968 -0.255785886340153 0.798453133920719 MARCH1 other 1 1 1 1.44974707041528 -0.255785886340153 0.367549176798268 -547.101767104665 484.110547750994 -1.13011742802611 0.260150312823962 -1069.95337562301 772.983598246054 -1.38418638901369 0.168265787753384 SFRP2 other 1 1 1 -1.13011742802611 -1.38418638901369 8.37637416101651e-05 1014.03361344538 814.243950831024 1.24536831057873 0.214900289538802 -3192.42352941176 1274.10855459827 -2.50561344862671 0.0132703677086789 RPS3A essential 0.620521797848103 1 1 1.24536831057873 -2.50561344862671 0.156962941448883 -2.68255550521068 3.91710053489466 -0.684831926399055 0.494459764056307 -11.4294970548255 6.25446910880325 -1.82741282369408 0.069536418094956 RNF175 other 1 1 1 -0.684831926399055 -1.82741282369408 6.97303141944186e-06 366.169584562838 93.1052207248532 3.9328577034896 0.000125676886485386 13.3173575129536 145.560998933056 0.0914898744208141 0.927219980202268 PDGFC other 0.0584200572320839 1 1 3.9328577034896 0.0914898744208141 9.83496652222797e-14 108.597794192047 26.4738406326916 4.10207932044222 6.55700959749839e-05 -123.813606698371 40.0539891202164 -3.09116793153265 0.00235948771755002 CBR4 other 1.28326643182031e-09 1 0.612083365710604 4.10207932044222 -3.09116793153265 0.00766308776319648 61.5966197225362 38.192725593879 1.61278407771997 0.108799724924068 -72.2435535173092 65.0062496181899 -1.11133243252191 0.268124272046497 CYP4V2 other 1 1 1 1.61278407771997 -1.11133243252191 0.366296207206825 -36.0820753938794 31.8809872030078 -1.13177409357246 0.259535506090287 -144.015906403805 129.737939109588 -1.11005236704243 0.268752812432045 ROPN1L other 1 1 1 -1.13177409357246 -1.11005236704243 0.00016258770135872 386.576581459927 109.419431559222 3.53297925195942 0.000568167361017787 -468.336915313122 377.001822758706 -1.2422669786742 0.216357348961476 NDUFS6 other 1 1 1 3.53297925195942 -1.2422669786742 1.48834446219334e-12 757.143418845721 106.475185168752 7.11098475805165 4.38325138611645e-11 -885.12346137278 433.294960477333 -2.04277349636769 0.0428257207537826 MARCH6 other 1.87992789019641e-08 1 5.76572887329758e-07 7.11098475805165 -2.04277349636769 0.3765321702579 25.0129912819779 18.4427293893224 1.35625214435231 0.177565358223758 6.99268257824772 63.6566227668614 0.109850040330572 0.912711800852773 NKD2 other 1 1 1 1.35625214435231 0.109850040330572 1.66472607288302e-05 73.2945907838238 15.0785881289405 4.86083910224648 2.90212278523374e-06 44.6761392039991 62.634567983312 0.713282467532983 0.476771901861669 CDH18 other 0.134260157778015 1 0.0307741100146186 4.86083910224648 0.713282467532983 0.151586003720199 35.2064149646327 18.0128405036862 1.95451766518601 0.0525247398260847 39.6912217860352 67.9206991113632 0.584375931127523 0.559857129395571 ADAMTS16 other 1 1 1 1.95451766518601 0.584375931127523 0.00275945048802165 84.7334623923039 24.2806457712613 3.48975324587928 0.000631760724048082 111.896017231354 99.7001281821409 1.1223257108249 0.263482163888647 SRD5A1 other 1 1 1 3.48975324587928 1.1223257108249 7.73198520321687e-12 1040.29488028439 137.015854149483 7.59251465271629 3.1814427125182e-12 -85.9878019029032 570.634633602766 -0.150688017935416 0.880425632860935 MYO10 other 9.54126974076961e-08 1 4.28349446813451e-08 7.59251465271629 -0.150688017935416 0.77734674854722 8.80340318703473 16.1960002386673 0.543554152710923 0.58756063972189 -19.8534768532879 64.435301687052 -0.30811490492761 0.75842521345267 FAM105A other 1 1 1 0.543554152710923 -0.30811490492761 2.75066692198449e-06 8286.96816516291 1758.77503854284 4.7117840448934 5.52714042471611e-06 -11224.4008543136 7170.17557074391 -1.56542901126605 0.119575649799115 RPL37 essential 0.0240380782312224 1 0.0573938261702521 4.7117840448934 -1.56542901126605 0.000299943484347097 164.1032868884 40.2602253686732 4.07606478567032 7.38098592612276e-05 -15.2250487261809 167.025442209374 -0.0911540692530876 0.927490980661276 SKP2 other 1 1 0.684586444647886 4.07606478567032 -0.0911540692530876 0.855118752519208 -44.9522779132901 111.661375323337 -0.40257678882355 0.687832727349337 144.428220158942 457.324313604574 0.315811374690702 0.752584672968892 OSMR other 1 1 1 -0.40257678882355 0.315811374690702 0.0145124282851168 -268.411763772026 199.21694880605 -1.34733397625391 0.179851721717547 -797.529988887124 281.181076920957 -2.83635725995643 0.00517707283734604 PLK2 other 1 1 1 -1.34733397625391 -2.83635725995643 0.96084158267877 2.19947495749474 14.2363710276432 0.154496883596525 0.87742158145938 -1.66820084935559 21.1732304795515 -0.0787882062194849 0.937304035857456 GZMA other 1 1 1 0.154496883596525 -0.0787882062194849 0.149724663569653 161.734265129683 167.624910872757 0.964858172258504 0.336211298194442 -116.407646493756 248.63204810524 -0.468192444943716 0.640345171842973 PIK3R1 other 1 1 1 0.964858172258504 -0.468192444943716 0.115980735444791 -32.3825291828794 16.0622877044137 -2.01605959118645 0.0455324232089916 -42.2819688715955 23.3475478400215 -1.81098114291546 0.0720927361567664 HAPLN1 other 1 1 1 -2.01605959118645 -1.81098114291546 0.427989903089825 -111.252874303564 86.3097442336084 -1.28899552757848 0.199320052405446 -89.2823339022884 121.310088374729 -0.735984410682262 0.462852512778533 LHFPL2 other 1 1 1 -1.28899552757848 -0.735984410682262 4.25919653003667e-07 94.1269897646181 84.3670837997688 1.11568381322759 0.26628421185053 -380.856075037939 118.6007509007 -3.21124505659174 0.001607115532985 SSBP2 other 0.00401471864921257 1 1 1.11568381322759 -3.21124505659174 0.00833370442379184 178.912054281867 80.1071651525366 2.23340888347741 0.0269727064601319 1.43307014322437 112.999558718993 0.0126820861910454 0.989897952229439 IQGAP2 other 1 1 1 2.23340888347741 0.0126820861910454 2.86356480117353e-13 240.492335215912 45.9817037538684 5.23017451687357 5.44652499511483e-07 -58.0912056687832 67.6400464703989 -0.858828588981019 0.39176989563775 RASA1 other 3.69199409815303e-09 1 0.00605326787957062 5.23017451687357 -0.858828588981019 0.305405043104784 160.696774719009 149.869639316492 1.07224368759341 0.285266538030166 -25.9561003420753 217.330648236699 -0.119431385093031 0.905087261912072 LIX1 other 1 1 1 1.07224368759341 -0.119431385093031 5.69220132675023e-13 11.4194712968962 5.53483736156147 2.06319906998579 0.0407510070209833 -38.0617768021265 7.98696965103109 -4.7654840903537 4.2815237066651e-06 GIN1 other 7.2814639371789e-09 0.0623132960268038 1 2.06319906998579 -4.7654840903537 2.13881810357896e-13 230.88627858078 47.4872332419753 4.86207055703328 2.81077557327174e-06 -144.424952723522 68.5257878305733 -2.10760003344443 0.0366644726676465 PPIP5K2 other 2.76741674422082e-09 1 0.0298335719347063 4.86207055703328 -2.10760003344443 2.06395608147359e-07 2076.79631441833 518.61071854512 4.00453797068533 9.58826858637394e-05 -492.299329533582 748.373944731546 -0.657825319814118 0.511619905229274 PAM other 0.00200183100342124 1 0.879052463998762 4.00453797068533 -0.657825319814118 3.25146120676791e-06 284.624061793132 87.8272280501883 3.24072691478417 0.00150405286942493 -76.1540073000201 126.316471532764 -0.602882635779351 0.547605756874206 BDP1 essential 0.028186917201471 1 1 3.24072691478417 -0.602882635779351 3.45677326570161e-09 76.8186289900575 28.9325805817337 2.65509081614919 0.0089358864610613 -103.884667713239 41.7723448561635 -2.48692449683994 0.0141722180185323 GTF2H2 essential 3.79138891782152e-05 1 1 2.65509081614919 -2.48692449683994 1.12486435261954e-16 145.018611594389 63.6269478596249 2.27920113211044 0.0241251064988296 -442.154735055953 91.5054768833186 -4.83200295890221 3.42231394033401e-06 SLC30A5 other 1.54635102554608e-12 0.0498254686573229 1 2.27920113211044 -4.83200295890221 3.51884581745788e-10 2194.46426140232 858.019346569205 2.5575929845602 0.0115121997517212 -3537.22820338271 1222.67009325039 -2.89303567896981 0.00437244717494591 BTF3 other 4.06602634207258e-06 1 1 2.5575929845602 -2.89303567896981 3.66787637649698e-08 111.862042476832 44.376387527869 2.52075594045552 0.0127084336806085 -180.899535409651 65.128929184907 -2.77756041245604 0.00614449788260238 FBXL17 other 0.000376800940157535 1 1 2.52075594045552 -2.77756041245604 0.0330879725724729 52.2956827156972 61.1279711817964 0.85551150651096 0.393588550751047 -137.249664844798 89.1672468196517 -1.5392385628144 0.125785047142891 TNFAIP8 other 1 1 1 0.85551150651096 -1.5392385628144 8.12124624063339e-09 227.166101725776 47.6529956162487 4.76708964018029 4.33666939030938e-06 -51.3435922957635 71.8503154344617 -0.71459104925707 0.475957798099102 FEM1C other 8.70516384533493e-05 1 0.0454396218716617 4.76708964018029 -0.71459104925707 0.000114128103164136 127.239697362783 37.2598529597326 3.4149275226688 0.000814509985675974 -12.6909238183002 55.6067913962378 -0.228226148275098 0.819771241592768 COMMD10 other 0.83222212827288 1 1 3.4149275226688 -0.228226148275098 1.45110969556711e-09 149.183034779522 37.6722591783281 3.96002358322442 0.000114820917683235 -120.436278005541 56.8015435354648 -2.12029938817322 0.0356043678459449 ATG12 other 1.62379174933959e-05 1 1 3.96002358322442 -2.12029938817322 0.0580548924733179 -14.4809509313962 14.6868031988283 -0.985983861522122 0.325687603051509 -51.0581505661081 21.4602322249117 -2.37919841831153 0.0185752450583407 MEGF10 other 1 1 1 -0.985983861522122 -2.37919841831153 0.0722624478020305 125.186482771924 64.1637975341156 1.95104541163361 0.0528433126955316 -17.2587466544501 96.2843148504393 -0.179247748517071 0.857975771839232 YIPF5 other 1 1 1 1.95104541163361 -0.179247748517071 0.0101347583933708 -10.5770362062766 117.880081717167 -0.0897270857994003 0.928619187460607 -487.266055822418 177.686638871977 -2.7422774099154 0.00681518674449888 ARHGAP26 other 1 1 1 -0.0897270857994003 -2.7422774099154 0.85660753895722 -73.815582412887 134.147578136808 -0.550256541624683 0.582935527454536 -44.2245859150743 219.983129334873 -0.201036261502366 0.840933786660059 CXCL14 other 1 1 1 -0.550256541624683 -0.201036261502366 0.976916021030483 1.34926570055014 15.0207083346687 0.0898270354824715 0.928539889112677 5.30113561473735 24.6187279285827 0.21532938785934 0.82979178110819 SLC25A48 other 1 1 1 0.0898270354824715 0.21532938785934 7.37275658412985e-07 345.631930941929 80.2663947144999 4.30606024066871 2.91687556461539e-05 -113.001740624765 130.911587496574 -0.863191278829485 0.389349019964578 DDX46 essential 0.0067962070192509 1 0.282907761012046 4.30606024066871 -0.863191278829485 0.218927909787488 7.92002438429651 4.59113351616208 1.72506949676279 0.0865342023936482 3.83133382101924 7.2821715714679 0.526125178927491 0.599563038536074 TIMD4 other 1 1 1 1.72506949676279 0.526125178927491 0.0401906533037274 37.2493682612495 82.4018407833851 0.452045341549702 0.651876532015049 -265.345564733217 131.643276936337 -2.0156408356618 0.0455881437796887 RNF145 other 1 1 1 0.452045341549702 -2.0156408356618 0.316702403472297 2.24354036270262 2.44894065841186 0.916126879186021 0.361032712809321 5.98962178355534 4.00145322873 1.49686162530915 0.136475983012264 C1QTNF2 other 1 1 1 0.916126879186021 1.49686162530915 0.530243021470605 5.61823944792165 19.9861420695108 0.281106750286359 0.779005856323984 -27.8305649173488 32.6564110237621 -0.852223623015344 0.395413379428778 GABRB2 other 1 1 1 0.281106750286359 -0.852223623015344 0.0101924864846691 99.8453036257987 36.9627231689323 2.70124317327681 0.00767707558347038 -8.34343688333259 55.0462789275405 -0.151571315007784 0.87972215735334 FBXO38 other 1 1 1 2.70124317327681 -0.151571315007784 9.58928602332718e-05 66.4784164997657 23.1484197421331 2.87183389796438 0.00464515592560044 -65.4549083109615 37.0192180949764 -1.76813319349508 0.078980891469676 PCYOX1L other 0.705004308435014 1 1 2.87183389796438 -1.76813319349508 0.00169859001180175 429.81564351078 186.140317966654 2.3090948173183 0.0222589924003108 -451.634016833033 295.459614767348 -1.52858121469041 0.128406474193299 TNIP1 other 1 1 1 2.3090948173183 -1.52858121469041 0.000232062808049402 551.747200583898 186.214416797572 2.96296715406136 0.00353101447618294 -391.673633565623 279.562958774517 -1.40102120567958 0.163219626916573 G3BP1 other 1 1 1 2.96296715406136 -1.40102120567958 0.00222242454946824 92.1456888736432 28.9722121397759 3.18048509478972 0.00177603399174569 -4.57903119104208 45.8090896076363 -0.0999590087963409 0.920506039006771 ZNF300 other 1 1 1 3.18048509478972 -0.0999590087963409 3.12057635236945e-07 173.080732178174 32.2897526687035 5.36023716112049 3.00575969192022e-07 33.1896125289695 52.1371314422159 0.63658301887502 0.525347733208704 N4BP3 other 0.00297239433861048 1 0.00339440442008551 5.36023716112049 0.63658301887502 0.00181321070829849 519.888994969339 180.232290122303 2.8845496809509 0.00448568262892253 -180.385837035948 295.080865401278 -0.611309841424802 0.541901674292066 NHP2 essential 1 1 1 2.8845496809509 -0.611309841424802 1.22308080280994e-06 467.691651672603 107.160594887486 4.36439954596796 2.33515548916012e-05 -154.582482649727 175.446037193766 -0.88108278261653 0.379654999912847 RMND5B other 0.0110713274270356 1 0.228588370833884 4.36439954596796 -0.88108278261653 0.00103677132928414 276.161986424479 73.2644815880669 3.76938429698053 0.000233192709146903 220.123226406715 122.251583189945 1.80057567078461 0.0737395718605979 BOD1 other 1 1 1 3.76938429698053 1.80057567078461 0.643429445208023 66.9930207701689 80.7589576909379 0.829542909983424 0.408098140513321 96.6698361839324 130.968929155139 0.738112747867265 0.461583995729854 CPLX2 other 1 1 1 0.829542909983424 0.738112747867265 0.257703401369837 18.1000789577576 10.9843054684729 1.64781278249302 0.10145671949022 8.75393378828042 18.5517354532578 0.471866031635501 0.637699085132633 TENM2 other 1 1 1 1.64781278249302 0.471866031635501 0.0141391908181963 -8.209138233263 7.8172006828729 -1.05013783914347 0.295321505207729 28.1773288241231 12.9103132325474 2.18254416578268 0.0306043860916204 KCNMB1 other 1 1 1 -1.05013783914347 2.18254416578268 0.00449967582583082 48.8730886850153 21.9760729827976 2.22392275104256 0.0276478179578697 -68.8405417212758 56.3352186878831 -1.22198055363336 0.223631816379786 FAM50B other 1 1 1 2.22392275104256 -1.22198055363336 0.00231885249359047 6.37415547256893 3.76614144303537 1.69248966587712 0.0927456528835063 -19.4360248544053 9.52878511663333 -2.03971698558696 0.0432326087313367 MYLK4 other 1 1 1 1.69248966587712 -2.03971698558696 2.14239836514356e-09 47.4848010251298 10.433784856687 4.55106192789636 1.0904563244048e-05 -65.782884499995 27.3631127344589 -2.40407168359736 0.0174254676822987 FARS2 other 2.37699098612678e-05 1 0.11036508459301 4.55106192789636 -2.40407168359736 0.000376886221670664 139.801807672258 42.6480533089629 3.27803491192122 0.00129559588085075 -85.4165158995425 120.135500390003 -0.71100145770609 0.478172943279027 GFOD1 other 1 1 1 3.27803491192122 -0.71100145770609 2.06322046810733e-19 140.356904374212 14.7216662095957 9.53403659449401 3.20144383059041e-17 -28.5116228504611 42.9697115533762 -0.66352837428393 0.507984284714427 CDKAL1 other 2.90522074114193e-15 1 4.53164374220072e-13 9.53403659449401 -0.66352837428393 0.860585989775636 1.38428737155575 2.82658815346443 0.489737908884634 0.625044501533714 -0.342028383583924 6.67522656148738 -0.0512384681528642 0.959204588490627 PCDHB18P other 1 1 1 0.489737908884634 -0.0512384681528642 0.443754448447326 4.80539582106235 17.4665855549701 0.275119358957652 0.783600629144217 -24.5434440713369 25.4326373082915 -0.965037316964974 0.336069117053954 PSD2 other 1 1 1 0.275119358957652 -0.965037316964974 0.000268872087302753 319.747045264348 83.4419837406218 3.8319684040384 0.000189784649293862 51.4835562537621 123.23043838726 0.417782789118801 0.676732578663179 ZMAT2 essential 1 1 1 3.8319684040384 0.417782789118801 0.225283274123425 21.8135025403867 25.6569273304078 0.850199334451639 0.39652565715031 66.2464289176413 38.1867509885072 1.73480139584483 0.0847638132564212 GFRA3 other 1 1 1 0.850199334451639 1.73480139584483 0.204626098735489 5.28210778261117 12.4512462754302 0.424223219569131 0.671991226957715 -26.8177844157818 20.2532192883675 -1.3241245272639 0.187410991744214 KLHL3 other 1 1 1 0.424223219569131 -1.3241245272639 2.5241140687652e-06 227.466872238301 54.1050909210933 4.20416763683178 4.42808744338233e-05 -213.368946361187 157.388088588841 -1.35568675033973 0.177183613987035 DCDC2 other 0.0221516250674834 1 0.421066834991225 4.20416763683178 -1.35568675033973 0.000151378406138888 34.3287634590681 9.11051947725354 3.76803579036054 0.000233839702592977 -13.0723055746572 26.5018914517216 -0.493259343336721 0.62253200837987 KAAG1 other 1 1 1 3.76803579036054 -0.493259343336721 0.347358820813572 4.49211455825778 4.4794965621648 1.00281683352535 0.317643132391284 -3.53677248082072 7.4532313761679 -0.474528738250329 0.635846756399035 TRIM7 other 1 1 1 1.00281683352535 -0.474528738250329 8.48007770155246e-07 123.150188994736 43.3318494411973 2.84202475968294 0.00514356301009591 -207.497686139209 70.881225483248 -2.92739981179147 0.00398216259101345 TRIM41 other 0.00778131929894453 1 1 2.84202475968294 -2.92739981179147 0.00143126860572037 893.88236043195 328.300007556736 2.72276070623443 0.00722608070247964 -636.903844372822 529.386181725498 -1.20309873275664 0.230796472741937 HIGD2A other 1 1 1 2.72276070623443 -1.20309873275664 0.00834192305841681 76.0381382132627 45.6682637402407 1.66501049056221 0.0979571021594269 -117.175159656567 73.7389441719225 -1.58905393849108 0.114112521070869 FAM193B other 1 1 1 1.66501049056221 -1.58905393849108 0.0113107284043843 31.7771928820736 10.5169097293172 3.02153329256891 0.00297717320204837 28.2747529405994 29.5099114931294 0.958144281360603 0.339595925371623 PLA2G7 other 1 1 1 3.02153329256891 0.958144281360603 0.0228961742055721 -9.56088503790852 138.889249584133 -0.0688381934997567 0.945210711275329 -983.802247691361 386.22272747345 -2.54724069224795 0.0118716894032498 TNFRSF21 other 1 1 1 -0.0688381934997567 -2.54724069224795 1.74182802352334e-05 543.08139594038 156.087965332951 3.47932907435837 0.000654961114408952 -425.243679096505 252.449862916341 -1.68446785505851 0.0941301488442166 RNF44 other 0.140217155893629 1 1 3.47932907435837 -1.68446785505851 1.40007524325401e-16 148.312156947992 20.2029755325968 7.34110461643115 1.24837932500792e-11 -153.317432282407 56.3204048130825 -2.72223597808362 0.0072524597429889 MUT other 1.92146326384181e-12 1 1.66184255745055e-07 7.34110461643115 -2.72223597808362 0.272647384211512 9.89342823712949 7.39363010503405 1.33810159510055 0.182901829885017 -2.01485138352904 11.9341423705512 -0.168830848582878 0.866158667455417 RASGEF1C other 1 1 1 1.33810159510055 -0.168830848582878 0.108395776677555 -28.1255048789862 16.5781454472571 -1.69654108588121 0.0918303929936324 9.62482928987007 26.7226202018663 0.360175357699312 0.719215984187717 DOK3 other 1 1 1 -1.69654108588121 0.360175357699312 1.66953505039057e-13 191.520592757292 29.4011155326118 6.5140587113049 1.07391188663021e-09 -180.074976937815 84.1971533591906 -2.13872998971358 0.0340986878948732 ABT1 essential 2.1663886813868e-09 1 1.35355854190872e-05 6.5140587113049 -2.13872998971358 0.0149146520024831 5.09552378952051 48.5620519767681 0.104928098836478 0.916579895291773 -401.580385228382 150.659804152834 -2.66547794540477 0.00857241290812965 PPP1R18 other 1 1 1 0.104928098836478 -2.66547794540477 0.0137103209993864 48.7463378396822 34.5941051331606 1.4090937647338 0.160823461617624 -401.208431323021 189.05984387823 -2.12212399573033 0.0354271901263721 DAAM2 other 1 1 1 1.4090937647338 -2.12212399573033 4.26771331870876e-05 66.867975299119 20.7508634630021 3.22241893299243 0.00159350569398875 -103.225974049003 62.2300206837931 -1.65878096961466 0.0994815201060407 PRIM2 other 0.327376288678149 1 1 3.22241893299243 -1.65878096961466 0.101040099705092 -1.32775516882448 2.26725464074963 -0.585622428535632 0.559003500521166 -14.6210979248114 6.86832959405337 -2.12877057290181 0.0348957076802126 MLIP other 1 1 1 -0.585622428535632 -2.12877057290181 2.02446806785249e-07 41.938349810641 8.18784722288433 5.12202397883376 1.01337463145068e-06 6.614947305712 16.0597163139613 0.411896896333181 0.681063459231538 LGSN other 0.0019653536002712 1 0.0110721312232301 5.12202397883376 0.411896896333181 0.9806124203387 2.12254186774404 17.9625169444007 0.118165058622572 0.90609602339897 -4.79379746361909 52.5664280691001 -0.0911950391097054 0.927460102732284 FGD2 other 1 1 1 0.118165058622572 -0.0911950391097054 0.00734853129588848 172.699430153177 59.4472566553769 2.90508662417067 0.00421613461313215 23.115579330741 175.876442408506 0.131430787513036 0.895607202496323 SCUBE3 other 1 1 1 2.90508662417067 0.131430787513036 0.00127710760297793 42.2983217592593 14.7849712360208 2.86089983429981 0.0048537698388968 -26.691654265873 31.965948246553 -0.835002736662169 0.405099369709011 ANO7 other 1 1 1 2.86089983429981 -0.835002736662169 2.79551302439094e-07 14.442864806867 2.70993476831178 5.32959869578873 3.68686040841536e-07 3.09831008583693 8.48034550378545 0.365351869738551 0.715381157722667 CRIP3 other 0.00267502641303969 1 0.00413997555260961 5.32959869578873 0.365351869738551 0.0432708988883657 6.5956653607987 2.98066632176218 2.21281574278979 0.0284628137809501 -1.57869328952358 9.19702919117769 -0.171652525691443 0.863948398997625 TTBK1 other 1 1 1 2.21281574278979 -0.171652525691443 0.767191274397737 -5.30973832854712 8.1550371536672 -0.651099219843457 0.516027342153089 -14.3498787001922 24.6327879784314 -0.582551951194359 0.561112391472544 TCTE1 other 1 1 1 -0.651099219843457 -0.582551951194359 2.77926953361379e-23 559.200463139949 61.1704006749195 9.14168383679113 4.22625857392306e-16 -601.444626887186 178.398156176601 -3.37136122803758 0.000952884205197328 RPL7L1 essential 3.98297116862193e-19 1 5.94127430322104e-12 9.14168383679113 -3.37136122803758 0.000677490726945512 52.0937499999998 25.2317070802627 2.06461456746816 0.0407788656980924 -157.026442307693 76.2272551823388 -2.0599776540829 0.041226595948987 NFKBIE other 1 1 1 2.06461456746816 -2.0599776540829 0.115715819788409 11.3400739883343 7.31957202533576 1.54928101657885 0.123621179311815 -13.6128095140828 22.0873336008439 -0.616317467743719 0.538707738570606 CYP39A1 other 1 1 1 1.54928101657885 -0.616317467743719 0.0643482879200626 -75.7934967005725 95.964625335814 -0.789806623381735 0.43085512456648 -423.048425068723 184.657010452258 -2.29099574412367 0.0233198949281014 TPBG other 1 1 1 -0.789806623381735 -2.29099574412367 4.94793367075e-09 119.24217189675 21.4243206575234 5.56573876030353 1.16081479849515e-07 4.46956136900082 41.3231204797262 0.108161274296641 0.914011352035936 IRAK1BP1 other 5.37395075980158e-05 1 0.00134457178109693 5.56573876030353 0.108161274296641 2.94886184703439e-07 538.940144375954 98.0622995808246 5.49589543259436 1.62995552232103e-07 297.694099375904 189.515234264348 1.5708188343353 0.118331758978137 PHIP other 0.00281350908825552 1 0.00187184092183347 5.49589543259436 1.5708188343353 0.895878844122286 2.20935441919856 4.8764292613118 0.453068075185043 0.651145798852052 3.24584960450398 9.26198923025152 0.350448432168586 0.726487364600064 PRSS35 other 1 1 1 0.453068075185043 0.350448432168586 1.49774761400564e-10 88.917494645023 18.8305231928624 4.72198747397133 5.23944809525721e-06 -55.826260032517 38.6001552009768 -1.446270351553 0.150146842445949 MMS22L other 1.76000322121803e-06 1 0.0544954996387703 4.72198747397133 -1.446270351553 0.00241078286575631 24.6465686618482 8.95023271547107 2.75373495252755 0.00660604781705292 -0.766118486103031 18.5422409958293 -0.0413174700013529 0.967096674326628 FAXC other 1 1 1 2.75373495252755 -0.0413174700013529 0.0370384301890805 10.4444648066108 5.90691146415865 1.76817696862136 0.0790374512692549 -5.78356380877125 11.7271611410675 -0.493176800352622 0.622599424811655 GABRR1 other 1 1 1 1.76817696862136 -0.493176800352622 5.38203433038608e-09 1019.05843792294 255.787447301267 3.98400487856113 0.0001048151224109 -955.568787040695 507.822172478001 -1.88169961618226 0.0617887377759592 PNRC1 other 5.83197240040636e-05 1 0.956967228853235 3.98400487856113 -1.88169961618226 2.9607184742551e-13 267.060990105668 55.6803773969777 4.79632147967739 3.82184248572218e-06 -300.963729751086 110.543853939889 -2.72257316010299 0.00723506347219832 PM20D2 other 3.8148857540777e-09 1 0.0401981392648259 4.79632147967739 -2.72257316010299 4.52527978308405e-14 197.179085248014 35.4245704196674 5.56616729326777 1.15845059206299e-07 -154.982821558944 70.1208863284891 -2.21022336815467 0.0285941967138609 RARS2 essential 5.9602460023e-10 1 0.00134194916584577 5.56616729326777 -2.21022336815467 6.22353864273223e-26 67.1730696508355 6.85874767945091 9.79378055444273 6.95296773729635e-18 -13.1599532206333 14.0867669047103 -0.934206784967308 0.351669273551081 TBC1D32 other 8.9805662614626e-22 1 9.87321418696081e-14 9.79378055444273 -0.934206784967308 4.38560075257945e-07 106.958503860465 32.3006452408791 3.31134263922074 0.00116330888382722 -104.510126370668 62.6828107580596 -1.66728525901704 0.0975442027218626 RNF217 other 0.00412904310855355 1 1 3.31134263922074 -1.66728525901704 0.000243523553753076 244.666936204344 63.3801229264001 3.86031021884357 0.000167857671615856 141.978106584762 122.714549404919 1.15697859197021 0.249120267973688 RSPO3 other 1 1 1 3.86031021884357 1.15697859197021 0.219261692411168 -33.252221056117 23.1866351420465 -1.43411154108418 0.153541892835374 -86.9215769358124 51.9674466525017 -1.67261588811634 0.0964072752510235 ARHGAP18 other 1 1 1 -1.43411154108418 -1.67261588811634 3.55131401751207e-07 196.693721695292 49.1221398485729 4.00417657499516 9.65239797468229e-05 -104.33331553163 97.9315286509087 -1.06537002913068 0.288375998626455 ABRACL other 0.0033677110828067 1 0.884835322339126 4.00417657499516 -1.06537002913068 1.30983879083351e-06 98.1031472197338 40.4007854318479 2.42824851475286 0.0163166616267701 -217.916423619716 83.4664707863576 -2.61082589891094 0.00991904865962781 SLC18B1 other 0.0118226049260633 1 1 2.42824851475286 -2.61082589891094 4.14608008571049e-06 36.1506606528706 7.81758019674303 4.62427755687517 7.90943080330948e-06 11.1100608352928 15.9178876834987 0.697960750584392 0.486254250474013 MTFR2 other 0.0355940975358246 1 0.081016299718299 4.62427755687517 0.697960750584392 8.2800350752103e-05 123.585860785051 44.9739063445986 2.74794588306634 0.00671332317177973 -122.633733677376 90.6412937622431 -1.35295656744542 0.178052415186276 SLC2A12 other 0.61379900012534 1 1 2.74794588306634 -1.35295656744542 1.07060967075311e-22 180.785683495458 17.3196526238008 10.4381818401496 1.12202805409397e-19 42.391384960555 35.6122802421632 1.19035862551609 0.235713740718488 SHPRH other 1.5311859511111e-18 1 1.60517333418683e-15 10.4381818401496 1.19035862551609 8.48190321102368e-08 112.960891415153 54.863903758204 2.05892916247802 0.0411854731605705 -386.995747666228 111.628165275313 -3.46682888419571 0.000682732602617772 AIG1 other 0.000849377787551911 1 1 2.05892916247802 -3.46682888419571 4.92331210818043e-07 311.845259399114 97.6614388089529 3.19312579460509 0.00170675247781874 -400.730216713182 205.282657243811 -1.95208997239957 0.0527413495432622 DYNLT1 other 0.00461166645173261 1 1 3.19312579460509 -1.95208997239957 5.00350874821464e-18 131.510930938266 17.458570026588 7.53274356021058 4.32846042853956e-12 -47.1506092577108 36.0402902083449 -1.30827496074916 0.19278124559747 TIAM2 other 6.97639224763567e-14 1 5.81442089365719e-08 7.53274356021058 -1.30827496074916 1.75569481073978e-13 185.949199638811 31.5244642719932 5.89856810997456 2.24555885797634e-08 -100.727179445083 66.2638793045212 -1.52009179816024 0.130538384184794 TMEM181 other 2.27660946108627e-09 1 0.000269220051482783 5.89856810997456 -1.52009179816024 0.00254668203817428 14.2507701460964 16.1184029255821 0.884130407453615 0.378069575866432 -77.137938784954 34.3199136826049 -2.24761459187619 0.0260893361089935 PNLDC1 other 1 1 1 0.884130407453615 -2.24761459187619 1.58740346079674e-14 471.293507025234 75.9700061641823 6.20367867295811 5.53481380653477e-09 -311.182136829808 153.217016953465 -2.03098939672164 0.0440960730707129 WTAP essential 2.10950045905278e-10 1 6.80948142617973e-05 6.20367867295811 -2.03098939672164 2.338825474785e-17 572.628552323638 73.5555730488359 7.78497846714418 1.0841080687532e-12 -583.840848302482 237.585122018471 -2.45739650421836 0.01514201467681 ZMYM4 other 3.23927328257723e-13 1 1.47113464929809e-08 7.78497846714418 -2.45739650421836 3.62758306899659e-06 208.822580645161 48.1573059567828 4.33625960788923 2.61752921468246e-05 -12.6141439205964 96.9005482232294 -0.130176187357963 0.896598026177265 ARMT1 other 0.0313024143023716 1 0.255261449015833 4.33625960788923 -0.130176187357963 0.415274744975358 -2.43711649784349 4.02802924634771 -0.605039424689697 0.546037573717258 -11.1723535145075 8.49720105517174 -1.31482748754162 0.1905099121348 SLC22A3 other 1 1 1 -0.605039424689697 -1.31482748754162 0.560474188786801 -11.5364519897592 10.7199355905595 -1.0761680321959 0.283557262856586 -14.2064825631976 21.7404108858984 -0.65345970863929 0.514447236943642 LINC01558 other 1 1 1 -1.0761680321959 -0.65345970863929 0.00414664330518315 27.8805304575925 13.8698314575018 2.01015639901758 0.0461720026398528 -20.8160011658409 26.2784362903289 -0.792132413658937 0.429509927664003 VWDE other 1 1 1 2.01015639901758 -0.792132413658937 6.24756310174442e-08 318.034476904177 71.6412208747989 4.43926657056805 1.7540854371027e-05 -26.6077376727561 141.047673307925 -0.188643577371659 0.850630604304243 GNA12 other 0.000631503678324326 1 0.17386494852562 4.43926657056805 -0.188643577371659 6.78518151294718e-07 126.763778400961 83.7979064796413 1.51273204458585 0.13253935363887 -467.640960338808 157.312919992393 -2.9726799322104 0.00346147478622922 C7orf50 other 0.00628036400838391 1 1 1.51273204458585 -2.9726799322104 6.46889418167327e-05 213.92753861321 62.7515275739133 3.40912081162058 0.000837230429503675 3.08782451528074 123.153176719002 0.0250730399129387 0.980030029210585 SDK1 other 0.486008019869113 1 1 3.40912081162058 0.0250730399129387 6.07708899259309e-14 122.476152676039 14.4718113430812 8.46308383743503 1.96706739596088e-14 27.6399198074197 59.465416559674 0.464806628903083 0.642730738278032 WASH2P other 7.97921784727472e-10 1 2.72773235797895e-10 8.46308383743503 0.464806628903083 8.75598058555949e-15 155.81178948035 47.0468554839442 3.31184279751757 0.00116649002371275 -356.645634757276 91.0834986492386 -3.91558998113054 0.000137596346749555 CCZ1B other 1.16971144642489e-10 1 1 3.31184279751757 -3.91558998113054 4.0290629305932e-16 150.386170016217 37.169013164359 4.04600922147757 8.36211805280063e-05 -256.470341592594 71.6496478718383 -3.57950596004812 0.000465970355858108 C7orf26 essential 5.49926799396666e-12 1 0.770987284468218 4.04600922147757 -3.57950596004812 3.98068711033201e-10 95.6432346340403 22.9790714644021 4.16218883266042 5.2757645880989e-05 -65.4234597842612 45.4171507527054 -1.44050119173018 0.151795908709736 RBAK other 4.58813996336867e-06 1 0.497873904178893 4.16218883266042 -1.44050119173018 0.0931184886016823 30.1285436833185 25.0049229434043 1.20490448027018 0.230125179653555 -47.4693297203176 54.4902136546137 -0.871153305090745 0.385053368859283 CREB5 other 1 1 1 1.20490448027018 -0.871153305090745 0.865772098178166 10.7050903919765 129.125162418569 0.0829047583868671 0.934037801349015 -143.812744413876 330.48226747678 -0.435160244789777 0.664071586900491 EGFR og 1 1 1 0.0829047583868671 -0.435160244789777 0.0546092415317168 136.590365676649 62.8122325731132 2.17458224427318 0.0313059173146847 -83.4727966538163 190.762818789942 -0.43757372208749 0.662355489323874 CDCA5 essential 1 1 1 2.17458224427318 -0.43757372208749 0.241788832183769 939.715838201183 645.276143758803 1.45630029451769 0.147358669866801 -156.467403976143 1572.57339536227 -0.0994976796870571 0.920873377760443 IGFBP3 other 1 1 1 1.45630029451769 -0.0994976796870571 0.000781852864955732 70.7090836572245 19.686297458692 3.59179189512879 0.000443658274088409 -35.0826926232058 72.0507832559586 -0.48691618658156 0.627023772757741 SSC4D other 1 1 1 3.59179189512879 -0.48691618658156 1.8387935536928e-05 904.250632223901 279.263898350701 3.23797897817905 0.00148010932893861 -2715.60816261874 1022.09075391149 -2.65691490919592 0.00873394432705474 MDH2 other 0.147691898232606 1 1 3.23797897817905 -2.65691490919592 3.65605681842176e-05 80.9215951306888 21.2234226962197 3.81284377590532 0.000198737112133203 -129.844892972447 77.8534182933714 -1.66781235581922 0.0973984044242248 POMZP3 other 0.283125040018581 1 1 3.81284377590532 -1.66781235581922 0.265209768098929 148.049448957827 125.095283041942 1.18349345680915 0.238485855550015 -150.268266027623 320.168215210742 -0.469341611342379 0.639506976398239 NIPSNAP2 other 1 1 1 1.18349345680915 -0.469341611342379 0.00618208421513812 374.541838387296 160.412159986386 2.33487186020737 0.0208758243373047 -388.427949754433 410.558045931449 -0.946097521662721 0.345620414029553 CCT6A essential 1 1 1 2.33487186020737 -0.946097521662721 0.0265700843815725 61.6267726177464 37.8625711218416 1.62764362777773 0.10569918293393 -117.205129893215 96.9052671259028 -1.20948152117405 0.228380701920923 PSPH other 1 1 1 1.62764362777773 -1.20948152117405 0.390494301105111 2.45445325465609 4.57481186736755 0.536514577170675 0.592413977066564 -20.9111193066568 18.2002426989857 -1.14894727792955 0.252443767304603 TRIM50 other 1 1 1 0.536514577170675 -1.14894727792955 0.000138665592862761 44.6629144552297 12.7293420555868 3.5086585198351 0.000589662562609475 -49.5397836659738 39.9139172319182 -1.24116566605389 0.21641967927791 ATXN7L1 other 0.997560275054702 1 1 3.5086585198351 -1.24116566605389 1.1440413835459e-09 84.0371182230018 16.8243301908026 4.99497556633445 1.60710741008642e-06 -138.854290383006 51.5506640076637 -2.69354998729722 0.00786934865013765 TMEM168 other 1.2873897689042e-05 1 0.0173390818474224 4.99497556633445 -2.69354998729722 1.05903142042687e-14 349.163550701209 42.5516360294852 8.205643384881 1.06088201820844e-13 -158.045045614923 143.037555610498 -1.10491992777961 0.270999493538713 SLC12A9 other 1.41179478657107e-10 1 1.45828842222932e-09 8.205643384881 -1.10491992777961 3.10398419122602e-06 373.023144910756 81.5731969425254 4.57286411336287 9.90999422320841e-06 -263.458037669231 274.478734124194 -0.959848632754269 0.338655739467394 GIGYF1 other 0.0269643106691804 1 0.100685541307797 4.57286411336287 -0.959848632754269 0.0397558822538448 57.1262254403449 29.1376084693516 1.96056671914008 0.0516993369329432 -100.971209779116 96.0073619016771 -1.05170278381904 0.294551971403245 TRIM4 other 1 1 1 1.96056671914008 -1.05170278381904 7.9075185127221e-14 485.938500922784 69.3216561811914 7.00990899081592 7.15084939628161e-11 -635.355777817467 227.639651959706 -2.79105934466079 0.00592328213352212 MEPCE essential 1.03477787257481e-09 1 9.35402609527597e-07 7.00990899081592 -2.79105934466079 2.4553949446501e-07 155.72731655246 31.3267488889439 4.97106536987056 1.74617180185581e-06 -211.033297751455 115.803425203214 -1.82234072421545 0.0703306568729625 TMEM209 other 0.00236184439725894 1 0.0187923009315723 4.97106536987056 -1.82234072421545 0.0168249239801503 3.81665349949456 3.53967186619869 1.07825065253671 0.282586348844911 -30.3006991343646 12.5896727509765 -2.40679005195067 0.0172620153223523 AGBL3 other 1 1 1 1.07825065253671 -2.40679005195067 2.68574080095556e-08 51.5735386032434 8.34126592369679 6.18293902568525 5.21477012323691e-09 10.7423385637685 29.9917106778718 0.358176920254647 0.720692040082942 ZC3HAV1L other 0.000278565035875111 1 6.4209464527416e-05 6.18293902568525 0.358176920254647 4.95839543115322e-07 145.191883925007 25.8990818681328 5.60606297413408 9.16982705869923e-08 44.128202383683 92.1161558460226 0.479049543246744 0.632574198158474 TMEM140 other 0.00464353732127499 1 0.00106755126617376 5.60606297413408 0.479049543246744 8.7827212296046e-18 221.689028575094 22.1700267682993 9.99949304942135 1.68643429562459e-18 125.359892242071 91.3781985402785 1.37187966325264 0.172070585663653 TLK2 other 1.22132521418882e-13 1 2.40215701068767e-14 9.99949304942135 1.37187966325264 0.024979864322332 223.049938166186 131.577578727341 1.69519716294823 0.0921551991142062 -844.494687339632 508.349105416333 -1.66124948060644 0.0987946513574522 EPHA1 other 1 1 1 1.69519716294823 -1.66124948060644 9.86868965137048e-07 113.394093686354 22.3372699313611 5.07645267460152 1.12385014919952e-06 -9.86588217545479 63.4734738412687 -0.155433153070004 0.876688818791419 NOM1 essential 0.00900912678273611 1 0.0122477189259763 5.07645267460152 -0.155433153070004 0.00783675488981075 116.378766424079 40.6774530217461 2.86101409451233 0.00483030825616624 -26.7484769651267 114.375152907698 -0.233866152613698 0.81540990823053 NCAPG2 essential 1 1 1 2.86101409451233 -0.233866152613698 0.0274042451970387 2.1407038877208 1.30301148949984 1.64288949481367 0.102446059018128 -8.15711922968756 4.73263581399112 -1.72358904219349 0.0867889993302524 RAB19 other 1 1 1 1.64288949481367 -1.72358904219349 1.17311506763222e-07 305.586059166312 53.3274960929342 5.73036578791857 5.07255194070804e-08 -50.1531948589878 191.784061281537 -0.261508670344421 0.794047433563903 LUC7L2 other 0.00116021080188827 1 0.000598561129003549 5.73036578791857 -0.261508670344421 0.156197403025018 27.1090984744255 14.2648960090065 1.90040631612803 0.0592364039479114 4.55918245239989 50.1371532948163 0.0909342105163211 0.927662275721096 DENND2A other 1 1 1 1.90040631612803 0.0909342105163211 6.78647512163211e-18 105.957935925654 19.1005505323299 5.5473760165346 1.30055808624941e-07 -85.5647468818782 36.8865073992597 -2.31967602559182 0.021725764182438 MCPH1 other 9.44948795936055e-14 1 0.00150240470123532 5.5473760165346 -2.31967602559182 4.37402604747545e-05 357.422380454071 104.241696372438 3.42878514924645 0.000788213484516689 62.8160858091819 202.973230349581 0.309479657494704 0.757397929653499 MFHAS1 other 0.335356577059943 1 1 3.42878514924645 0.309479657494704 3.09666660348749e-12 106.914115827645 40.7321527101441 2.62480887245174 0.00974235253699541 -274.9349758248 76.3773957981778 -3.59969036586817 0.000456500302689801 FBXO25 other 3.87362025430249e-08 1 1 2.62480887245174 -3.59969036586817 0.00262258893895108 -17.9495129500352 16.7842315732846 -1.0694271508149 0.286572575803113 -99.3735934506181 31.9419157790219 -3.11107180101835 0.00222688106217127 CSGALNACT1 other 1 1 1 -1.0694271508149 -3.11107180101835 3.43346845006365e-06 148.799459274582 83.4739576439467 1.78258541315697 0.0766631362728625 -351.686105094002 156.879797611413 -2.24175521927379 0.0264347935727963 ATP6V1B2 essential 0.0297132359668508 1 1 1.78258541315697 -2.24175521927379 1.3149772935829e-24 182.704656019606 30.1540746936674 6.05903705803235 9.98625136159878e-09 -221.729603198188 61.0974845755875 -3.62911181595165 0.000385690346137046 CCDC25 other 1.89146333908965e-20 1 0.000121542665322019 6.05903705803235 -3.62911181595165 4.81792663204267e-18 103.158219493964 17.0914303258242 6.03566919370687 1.17459269685796e-08 -44.9410579772371 32.2369796513877 -1.39408401355313 0.165340249000849 HMBOX1 other 6.7181168957203e-14 1 0.000142583807471588 6.03566919370687 -1.39408401355313 2.93058156056165e-07 3.11212062632906 2.38507473536639 1.30483149235615 0.193884136518602 -12.7504349507055 4.39180493460923 -2.90323344058996 0.0042325419031731 GNRH1 other 0.00279694704140004 1 1 1.30483149235615 -2.90323344058996 6.00252796971363e-29 162.797596176746 23.3329969069963 6.97714043445195 9.02342475059599e-11 -145.465697092866 43.1578736241091 -3.37054828882035 0.000954029438096516 BIN3 other 8.69045999455139e-25 1 1.17737646145776e-06 6.97714043445195 -3.37054828882035 0.350275346343482 -20.2022846987353 15.6532877857744 -1.2906096773545 0.198851613953928 -13.8920123391302 28.3271362282247 -0.49041358177564 0.624567543742035 DOK2 other 1 1 1 -1.2906096773545 -0.49041358177564 1.38011621450513e-08 0.900282093762996 72.9600697992896 0.0123393809276723 0.990170819237105 -575.961521813759 133.601464412366 -4.31104198106714 2.88811044936885e-05 SLC25A37 other 0.000145933488521772 0.417129792202342 1 0.0123393809276723 -4.31104198106714 9.26617217056575e-25 214.644884252004 30.8704975649988 6.95307498041009 9.54589797428402e-11 -117.981396737265 56.5287792784208 -2.0871032108472 0.0385261642725694 CHMP7 essential 1.33358749878782e-20 1 1.24468963686689e-06 6.95307498041009 -2.0871032108472 0.0239568303396392 13.7810396261787 62.745080948777 0.219635378866258 0.826445992494902 -195.303994297631 114.027001292249 -1.71278725288119 0.0887642531858097 DOCK5 other 1 1 1 0.219635378866258 -1.71278725288119 0.606102008736402 -15.2762836185819 15.8290003104901 -0.965082021538536 0.336179780714931 -2.32829276071006 55.1371561753003 -0.0422272913987005 0.966378103455947 STAR other 1 1 1 -0.965082021538536 -0.0422272913987005 1.14401703563094e-30 400.706609516711 27.2772641384671 14.6901319532124 6.26927664196394e-30 22.313742475688 92.4408012639433 0.241384130931278 0.809618316344508 PLPBP other 1.6587102999613e-26 1 9.09546655216129e-26 14.6901319532124 0.241384130931278 4.11366486917107e-33 578.401141033107 37.074766636319 15.6009381449888 2.9123127341637e-32 38.0733208697079 114.112051924213 0.333648551819876 0.739151211740689 ERLIN2 other 5.97633232193173e-29 1 4.2324640965601e-28 15.6009381449888 0.333648551819876 0.372960792976469 87.7581101424575 63.1272839632964 1.39017718857478 0.166729572331611 145.893214047375 224.167871282123 0.650821249329541 0.51625194005002 TACC1 other 1 1 1 1.39017718857478 0.650821249329541 1.74825300649462e-06 430.124827590772 84.7410236789703 5.07575680487695 1.37499732038953e-06 159.62250930734 239.595094755737 0.666217768231325 0.506509493121846 GOLGA7 other 0.015601409829958 1 0.014899470963741 5.07575680487695 0.666217768231325 4.12707216517293e-10 110.429950898822 24.2825755382507 4.54770338199378 1.17573579729203e-05 -326.713232179988 84.6962197712015 -3.85747124325704 0.000175145319667311 PLPP5 other 4.75232359819663e-06 1 0.118631741946766 4.54770338199378 -3.85747124325704 7.98180162980531e-10 149.478782860691 21.5918296290006 6.92293267541914 2.05683940315014e-10 127.268364469054 61.4363580541625 2.07154799698338 0.0403644897232278 GINS4 essential 9.05615212917711e-06 1 2.65496830158621e-06 6.92293267541914 2.07154799698338 4.0980876746576e-33 553.698600417591 35.8291878011704 15.4538418088144 6.71100388222495e-32 -59.1585839966941 125.482699718436 -0.471448128940776 0.638065241713519 NSD3 other 5.95411158251003e-29 1 9.75108864087286e-28 15.4538418088144 -0.471448128940776 0.352434282255825 -1.7475876630424 3.12714442613734 -0.558844563888922 0.577129849330489 -16.4435805855384 11.3455054905511 -1.44934754993801 0.149399881044329 TRIM55 other 1 1 1 -0.558844563888922 -1.44934754993801 0.00139892537311945 24.7254717627819 10.5508370549927 2.34346067841903 0.020454694693247 -68.2457377322091 38.2680240006525 -1.78336194549908 0.0766049831091135 ADHFE1 other 1 1 1 2.34346067841903 -1.78336194549908 4.23908294301603e-06 126.956443914081 29.8319540677636 4.25572001169276 3.63086311820235e-05 -89.2454555242523 92.8681992763294 -0.960990481345529 0.338083170294027 MRPS28 other 0.0363670925681345 1 0.348345007560333 4.25572001169276 -0.960990481345529 0.00191779584118182 112.056322993087 56.6611596210333 1.97765671833321 0.049812188215877 -372.714347923383 192.101833145116 -1.94019152145117 0.0542448043878396 LACTB2 other 1 1 1 1.97765671833321 -1.94019152145117 2.07132225823793e-06 89.2073432033606 25.8891801227274 3.44573844287359 0.000745199071851546 -195.40227825729 85.0670602549882 -2.29703809760879 0.023048271281465 TERF1 other 0.0183477725634716 1 1 3.44573844287359 -2.29703809760879 0.000135279883863479 557.516697415061 181.822502610764 3.06626896786568 0.00258323304225598 -928.440931987313 600.707603373874 -1.54557879203247 0.124371161423085 RPL7 essential 0.9745562833525 1 1 3.06626896786568 -1.54557879203247 0.106849203386477 73.6557621870462 36.1484847384107 2.03758920242599 0.0433724802270868 12.1506014742284 144.183338431362 0.0842718833286874 0.932954150130002 SLC26A7 other 1 1 1 2.03758920242599 0.0842718833286874 0.166838354362118 18.236994400475 52.7805702142655 0.345524770316822 0.730174494877321 -415.090598638181 249.07874516173 -1.66650349217335 0.0976590735943144 SYBU other 1 1 1 0.345524770316822 -1.66650349217335 2.14230671276011e-08 607.404569324561 111.170459187496 5.46372277099382 1.88089624530708e-07 -751.585647557005 515.499102726681 -1.45797663581094 0.146923703150839 MTDH other 0.000223763936147794 1 0.00215136912538223 5.46372277099382 -1.45797663581094 0.0028637870605106 50.0238891001553 15.3088304164192 3.26764930693222 0.0013408037285019 -10.8935241500993 65.987157377225 -0.165085519411374 0.869096020609668 LRP12 other 1 1 1 3.26764930693222 -0.165085519411374 3.17067093657853e-08 212.325491913536 39.046129651769 5.43781147599392 2.09071095407634e-07 -212.354300267985 184.264037648768 -1.15244571310633 0.250935409678463 EBAG9 other 0.000327118120526807 1 0.00238382862983785 5.43781147599392 -1.15244571310633 8.1379139343484e-08 490.621158637874 90.885965105336 5.39820596138522 2.6191750368417e-07 -319.127906976744 391.647260607429 -0.814835029055967 0.4164760046453 POLR2K other 0.000815825871918427 1 0.0029683110692527 5.39820596138522 -0.814835029055967 3.39374380248123e-06 2256.99467488082 469.853519147993 4.80361343035916 3.74206847085434e-06 -1985.52340642366 2541.21876321026 -0.781327225805383 0.435841500376766 MAL2 other 0.0293830338418825 1 0.0394002389296254 4.80361343035916 -0.781327225805383 4.23346413913747e-09 1455.88600181827 253.26886452101 5.74838128868185 5.12940409847107e-08 -2091.55652810748 1342.33084825044 -1.55815276899399 0.121376995673565 EIF3H essential 4.61362921883202e-05 1 0.000605013213414662 5.74838128868185 -1.55815276899399 5.45384863629819e-11 176.075264390167 25.3157426033568 6.95516885081694 1.09570179711531e-10 -88.5129764479456 134.718862027616 -0.657019923682262 0.512202466608007 UTP23 essential 6.52607527819442e-07 1 1.42605588894558e-06 6.95516885081694 -0.657019923682262 4.85739297903841e-11 1497.67759004437 202.40563545017 7.39938681407457 9.26665788730007e-12 1545.49117404146 1880.01213640889 0.82206446655902 0.412353751291996 NDUFB9 other 5.82207122467544e-07 1 1.23580149585034e-07 7.39938681407457 0.82206446655902 0.308059620645871 67.8710339678983 47.1921653629121 1.43818435636432 0.15245107244553 242.758050833078 265.224610437179 0.915292326880721 0.361497533803477 FAM83A other 1 1 1 1.43818435636432 0.915292326880721 0.375490325706174 5.43290314155556 4.92193485389374 1.10381451661385 0.271465061592202 -36.6964813337731 40.5423304312096 -0.905139910396567 0.3668623826484 GSDMC other 1 1 1 1.10381451661385 -0.905139910396567 0.914718582007047 -2.07877144172456 5.93653165180054 -0.350165983044001 0.726711974994851 -10.2927817030617 32.5253880639008 -0.316453770907824 0.752104003775677 FAM135B other 1 1 1 -0.350165983044001 -0.316453770907824 1.22568322795305e-05 166.84588810246 35.7419235655828 4.66807243309989 9.46312443937466e-06 -48.6826761038083 131.724470337891 -0.369579592758512 0.712477241108671 ZNF7 other 0.100334429040237 1 0.0962778280461978 4.66807243309989 -0.369579592758512 1.82200803676752e-05 298.859875294911 71.4215812839953 4.18444775265542 6.15094694850917e-05 -318.848163127738 263.219464057837 -1.21133961072756 0.228620068461022 ARHGAP39 other 0.146380125673903 1 0.575790143849943 4.18444775265542 -1.21133961072756 0.00220777531264253 652.743851574861 184.39221791532 3.53997505401571 0.000595779615407982 315.448163862121 708.934411281647 0.444960998989791 0.657255229999572 SLC39A4 other 1 1 1 3.53997505401571 0.444960998989791 0.00960872750479121 389.961975932743 126.992810998734 3.07074056291762 0.0026749376679468 225.94001501914 535.838726779685 0.421656748061133 0.674076631516372 NAPRT other 1 1 1 3.07074056291762 0.421656748061133 0.000200637681750532 79.1660626060201 40.3649960110266 1.96125530606752 0.0517260716060981 -228.056101939482 104.523380764482 -2.18186687295688 0.0306971131821219 VLDLR other 1 1 1 1.96125530606752 -2.18186687295688 1.25508436136529e-12 480.996746881031 81.4691264479074 5.90403712243788 2.35655903113111e-08 -257.795711352122 195.853766043906 -1.31626629683664 0.190133409901891 AK3 other 1.58881129305233e-08 1 0.000282245075158573 5.90403712243788 -1.31626629683664 6.32219947918066e-23 364.245132662353 35.4249281196042 10.2821699858518 3.73507377798554e-19 36.5178240194265 84.2208555616679 0.433595975437314 0.66519660273494 UHRF2 other 9.05150012594629e-19 1 5.33443236971894e-15 10.2821699858518 0.433595975437314 3.52496893948584e-20 1337.23717778739 139.489419089212 9.58665672650158 2.44275450389573e-17 178.887471564344 330.539464971468 0.541198527019415 0.589157886033525 NFIB other 4.98430608043297e-16 1 3.45918465296674e-13 9.58665672650158 0.541198527019415 0.000457920342586844 485.859221370233 138.415064840541 3.51016142592543 0.000586585546268539 47.1517717573286 318.162078119317 0.148200477052598 0.882377177154402 PLIN2 other 1 1 1 3.51016142592543 0.148200477052598 1.96442121969502e-26 363.585899524872 30.8395683414945 11.7895910701081 2.41710240705796e-23 57.6457423356565 70.7501161684212 0.814779472565534 0.416440665699229 HAUS6 other 2.83662424123961e-22 1 3.48546167097758e-19 11.7895910701081 0.814779472565534 3.42507828004179e-07 148.340657783137 36.1227033365929 4.10657686388786 6.55686519240068e-05 -135.191970402233 85.0328133991732 -1.58988001217361 0.113953381691513 CDKN2B other 0.00325279684255569 1 0.612083365710604 4.10657686388786 -1.58988001217361 8.54752007229957e-07 657.047802777545 411.26807604469 1.59761440541801 0.112219363309394 -3795.5503697471 968.124706544834 -3.92051803253027 0.000133656155994148 CDKN2A ts 0.00783978541031316 1 1 1.59761440541801 -3.92051803253027 3.58721162307962e-09 115.753046194185 21.4549013990028 5.39517959283491 2.6139106956573e-07 -34.8241883242078 47.1915786258739 -0.737932261183453 0.461708498367959 C9orf72 other 3.92907289075911e-05 1 0.00296286777352755 5.39517959283491 -0.737932261183453 1.71651243173859e-23 165.780062413864 16.9324696059219 9.79066056352966 8.75566926932123e-18 -69.2098151345701 38.9604999251898 -1.77640983220091 0.0777061507120721 ZCCHC7 other 2.4611355246268e-19 1 1.24260458270207e-13 9.79066056352966 -1.77640983220091 1.63120509466182e-07 56.9600555212833 24.381134521861 2.33623482411004 0.0208026301627751 -195.388273699363 54.1554606070335 -3.60791453916628 0.00041985991156361 FBXO10 other 0.00159548170308873 1 1 2.33623482411004 -3.60791453916628 6.25273834441061e-12 807.969017482718 137.439451211807 5.87872703476937 2.85700759573394e-08 -592.595389004846 339.545244620457 -1.74526193016559 0.0831177988132504 SIGMAR1 other 7.73963952271145e-08 1 0.000340898146322974 5.87872703476937 -1.74526193016559 2.70871733925517e-05 122.871352375255 38.3332432459927 3.20534716008148 0.00164028384031582 -77.9365169566156 52.6499904305149 -1.48027599472165 0.140842516307876 CEP78 other 0.213880321107588 1 1 3.20534716008148 -1.48027599472165 0.54915290579654 69.6364452423696 75.7522138513066 0.919266140248501 0.359403384160676 102.333931777379 103.616395264471 0.987622967544672 0.324896614688674 NTRK2 other 1 1 1 0.919266140248501 0.987622967544672 0.0012109897231217 2.70688872496185 11.3227646070218 0.239066060181378 0.811372217338459 -46.812801452647 15.2656321467075 -3.06654850600102 0.00255840746759795 IDNK other 1 1 1 0.239066060181378 -3.06654850600102 0.735302331396049 4.15925374836688 6.891469765576 0.603536529920369 0.54703402501163 -1.16728188963315 10.4456039771792 -0.111748625755231 0.911167304398989 SHC3 other 1 1 1 0.603536529920369 -0.111748625755231 2.98363527193703e-07 18.0241876718667 18.4513384431547 0.97684987608872 0.330165613419581 -118.745272832683 27.9672378726583 -4.24587059234666 3.73906995574732e-05 AUH other 0.00284549295884635 0.538986934120977 1 0.97684987608872 -4.24587059234666 6.47783608674981e-10 442.641422567295 114.188759816727 3.87640099846721 0.000156552079794894 -503.81836119221 176.38112594964 -2.85641878335702 0.00487652113324373 MFSD14B other 7.38278978806876e-06 1 1 3.87640099846721 -2.85641878335702 0.986161674966278 -8.7209336250908 54.1120553523885 -0.161164338857549 0.872171167760973 -9.94583913533546 86.6105324366887 -0.114834060656604 0.908723383327227 ZNF462 other 1 1 1 -0.161164338857549 -0.114834060656604 2.62181341504213e-14 204.091316558721 29.634577634777 6.8869318494762 1.27380796567533e-10 -65.301434057431 46.5233626351682 -1.40362670191144 0.162392398116645 INIP other 3.46865914810073e-10 1 1.65442178581912e-06 6.8869318494762 -1.40362670191144 0.000673921541192771 238.815179198876 82.3237705306084 2.900926156074 0.00425505823809572 -118.54528226751 129.115414743166 -0.918134232874655 0.359956926138877 UGCG other 1 1 1 2.900926156074 -0.918134232874655 5.76493607342221e-08 210.522829139681 41.3416380071834 5.09227111666695 9.95988236286475e-07 -29.9753585143577 64.902292202165 -0.461853618682482 0.644821577466756 SNX30 other 0.000584276271041341 1 0.0108851554343749 5.09227111666695 -0.461853618682482 0.063093077400603 -5.52147129954459 137.390662340549 -0.0401881118081996 0.967994542219125 -421.516914756752 203.142406928482 -2.07498237876619 0.0396301999026096 STOM other 1 1 1 -0.0401881118081996 -2.07498237876619 0.000184663499643853 3981.92435807072 1040.56333252814 3.82670062801105 0.000187529769515443 432.484637280155 1538.55099269656 0.281098669678901 0.779007209103996 GSN other 1 1 1 3.82670062801105 0.281098669678901 3.44046864805168e-05 106.989948621759 52.351739653921 2.04367513532562 0.0426677922540984 -209.603148956124 77.8183467980232 -2.69349269909508 0.00784441624552732 MRRF other 0.267702865504901 1 1 2.04367513532562 -2.69349269909508 0.000152741983757808 52.1804768805165 13.2639338194333 3.93401215588587 0.000125128677874919 9.72845035787991 19.0401266427773 0.510944624497564 0.610107573211806 NR6A1 other 1 1 1 3.93401215588587 0.510944624497564 0.000865023291637318 463.502196950116 128.940708994213 3.59469247971111 0.000435118039738003 128.52093703188 185.501255952437 0.692830549162608 0.489446020892141 CRB2 other 1 1 1 3.59469247971111 0.692830549162608 5.78297743377413e-08 161.414810770743 51.9902220336875 3.10471478013987 0.00225772275731844 -257.235774793549 82.7356884504021 -3.10912714466327 0.00222621093918677 ALAD other 0.000585931273589995 1 1 3.10471478013987 -3.10912714466327 0.00340046565401154 41.2821426949453 12.1359131539281 3.40165113010745 0.00084970648160749 24.296877902968 20.1152866954269 1.20788126318338 0.228909293426809 ASTN2 other 1 1 1 3.40165113010745 1.20788126318338 3.65022714959998e-12 67.1482891041441 10.7257438254174 6.26047854555495 3.46583987629176e-09 -20.1351934429988 16.8383594216042 -1.19579306622738 0.233568864900478 WDR31 other 4.55402339184094e-08 1 4.29452219071311e-05 6.26047854555495 -1.19579306622738 6.58346570676462e-13 882.784656151586 143.12977943281 6.16772176726505 5.57036396627926e-09 -407.957189557714 227.772461357342 -1.79107336824924 0.0751958350697063 POLE3 other 8.40313562811437e-09 1 6.85043360573024e-05 6.16772176726505 -1.79107336824924 0.0101929933574251 477.494753249299 377.330841391622 1.26545381630684 0.207583503639914 -842.395549773566 507.839762343125 -1.65878218335412 0.0991561371243522 SURF4 other 1 1 1 1.26545381630684 -1.65878218335412 0.152744751003632 28.8620235620235 16.4313063678276 1.75652640854748 0.0809482275849878 37.7373065373064 22.7102915081567 1.66168305341887 0.09857181468479 GBGT1 other 1 1 1 1.75652640854748 1.66168305341887 0.00371765968916403 26.9459738092025 58.5985889014179 0.459839977623599 0.646267238790861 -203.378269247291 78.8663162321597 -2.57877226886829 0.0108333880762458 SURF1 other 1 1 1 0.459839977623599 -2.57877226886829 0.00380672617684397 4.08982068999364 28.4559459902356 0.143724643397799 0.885902222014525 -106.023202297525 38.2981173646807 -2.76836590394131 0.00631210352071825 SURF2 other 1 1 1 0.143724643397799 -2.76836590394131 1.26842034246646e-07 159.965708488918 49.11184487418 3.2571716435971 0.00137903672651698 -161.818328689842 68.1867153590562 -2.3731650342408 0.0188464350840395 SURF6 essential 0.00125142350987741 1 1 3.2571716435971 -2.3731650342408 3.17156242583246e-10 256.786518612157 46.5796843442441 5.51284368340483 1.42048922631862e-07 -47.0653021023831 62.6903852867085 -0.750757901504902 0.453922117565156 MED22 essential 3.67298644535657e-06 1 0.0016375399801001 5.51284368340483 -0.750757901504902 6.24151381730916e-09 123.764132475852 31.0952298305909 3.98016458312508 0.000104985255151434 -91.152981136244 41.8502608186821 -2.17807438599171 0.03089257860873 REXO4 other 6.73521756025831e-05 1 0.958410394277444 3.98016458312508 -2.17807438599171 0.0016590239947415 1275.11493759129 1151.83347287729 1.10703063213299 0.269973934425767 -3588.96649443414 1550.22270368236 -2.31512961712469 0.0219007208173794 RPL7A essential 1 1 1 1.10703063213299 -2.31512961712469 2.51304629092978e-06 612.729630951774 126.642413538001 4.83826558444351 3.10390451559709e-06 153.224709742125 177.962268133199 0.860995487130119 0.390553528806545 GTF3C5 essential 0.0220595203417816 1 0.032848621488564 4.83826558444351 0.860995487130119 4.30353608769925e-08 312.726627973883 77.8177523342392 4.01870548291698 9.05695591691618e-05 -153.456770820303 107.280255898162 -1.43042882901001 0.154581191522009 ASB6 other 0.000439907458884617 1 0.832696527001273 4.01870548291698 -1.43042882901001 8.91822744345755e-11 313.412671368571 81.1807793143884 3.8606758153284 0.000166022600419356 -322.302579443696 111.684634208871 -2.88582741687571 0.00446467464885317 PTGES2 other 1.05832605071511e-06 1 1 3.8606758153284 -2.88582741687571 1.65521817042716e-06 67.2781752683062 37.8737895118367 1.77637823242588 0.0776073571791981 -161.150989417857 52.2131481414587 -3.08640630098108 0.00239537898968049 NTMT1 other 0.0148042713163005 1 1 1.77637823242588 -3.08640630098108 4.0932816342228e-09 994.594677336441 190.032752727224 5.23380660998 5.35642213143906e-07 -71.8678174656439 263.479875700598 -0.272763972104306 0.785400066207542 CIZ1 other 4.46495160661023e-05 1 0.00595741269458652 5.23380660998 -0.272763972104306 0.0389324180299099 129.294872810841 59.9742080074126 2.15584127088198 0.0326489410406943 7.50376416514774 82.5096474786793 0.0909440822309504 0.927655206430167 SLC25A25 other 1 1 1 2.15584127088198 0.0909440822309504 2.38941646994091e-06 543.441486266485 163.429413052849 3.32523672523225 0.00110284542431446 -329.655642150548 222.594382067829 -1.480970180326 0.140644444111405 SH3GLB2 other 0.0210292543519499 1 1 3.32523672523225 -1.480970180326 3.82285817825145e-05 142.745496161611 46.0168302661324 3.10202800445099 0.00228188077965204 -64.0411421296953 63.1261329288762 -1.01449493511427 0.311917508456567 MIGA2 other 0.295123508421571 1 1 3.10202800445099 -1.01449493511427 0.964989387715742 -2.48937407750199 68.9769265532068 -0.0360899535815322 0.971256478863823 -22.414823756035 95.0922136624202 -0.235716710051658 0.813959706201592 PTGES other 1 1 1 -0.0360899535815322 -0.235716710051658 0.00344578400104576 -3779.60106915595 2301.8104388246 -1.6420123070977 0.102614807022454 -10841.0722503957 3182.83577863028 -3.40610480854311 0.000839378445212728 LCN2 other 1 1 1 -1.6420123070977 -3.40610480854311 6.48069285646077e-19 275.013451876135 31.2932855414386 8.78825751651938 2.60206349061791e-15 -3.13585504044473 43.6041462842205 -0.0719164416155427 0.942760524331522 LRSAM1 other 9.09824470118527e-15 1 3.63742455353478e-11 8.78825751651938 -0.0719164416155427 0.578055316811117 -10.3573139139772 157.02900038314 -0.0659579688382785 0.947494672687112 -192.282576714512 215.762815794953 -0.891175692188057 0.374190006956039 HMCN2 other 1 1 1 -0.0659579688382785 -0.891175692188057 9.90840102997683e-09 931.893558931916 169.845408830327 5.48671621652641 1.59596014163274e-07 111.730561098937 234.552682533907 0.476355929473478 0.63447890237076 GPR107 other 0.000105663188583673 1 0.00183375820273602 5.48671621652641 0.476355929473478 1.55115450347834e-09 18.6306694403934 2.9165650617311 6.38788062191738 2.02735389875968e-09 3.92843348693086 10.5944809960898 0.37079999373077 0.711313148706828 IDI2 other 1.73388050398809e-05 1 2.53378690266985e-05 6.38788062191738 0.37079999373077 0.000205953998964722 133.725227057069 42.5223004548416 3.14482578850795 0.00206983272675506 -52.0782160769961 63.6009511646291 -0.818827629514428 0.414418609541891 INPP5E other 1 1 1 3.14482578850795 -0.818827629514428 1.91053090578017e-07 1210.05340924495 225.554908787147 5.36478419269013 3.70676813288294e-07 221.665392435949 337.364314377783 0.657050502940056 0.5123373935978 SEC16A essential 0.00185822528649764 1 0.00416121790597438 5.36478419269013 0.657050502940056 1.06005319059016e-06 195.749679666663 38.7775752738575 5.04801237014504 1.62435958063992e-06 21.4227593276327 60.7124709357057 0.352855994781028 0.724820637495342 DPH7 other 0.0096560245130858 1 0.0175170937176209 5.04801237014504 0.352855994781028 0.00017334278208982 833.090974729239 193.633703835995 4.3024068549288 3.35832124814813e-05 565.910263022175 300.097075380133 1.88575734137141 0.0616299975617209 NOTCH1 og 1 1 0.323473502621627 4.3024068549288 1.88575734137141 0.512054190035153 41.6219353310397 174.661224109731 0.238300948268235 0.8120645433356 -243.453038019666 274.391252591384 -0.887247810272617 0.376765710939851 CACNA1B other 1 1 1 0.238300948268235 -0.887247810272617 0.407212110463889 36.9391538686319 44.135720900576 0.836944613453675 0.404125025077818 -30.7365011851037 64.5351302622447 -0.476275496155395 0.634659601649393 NACC2 other 1 1 1 0.836944613453675 -0.476275496155395 6.22950784357691e-08 114.896736763735 22.0062116448073 5.22110477797058 5.75638613553339e-07 -137.894437654815 108.561300260005 -1.27019883996007 0.205954727365634 PROSER2 other 0.000629865538064062 1 0.00638555914014719 5.22110477797058 -1.27019883996007 6.27170908188853e-15 200.599133313133 23.5566993234896 8.51558745809118 1.398550008294e-14 -21.7377048805448 116.131796857937 -0.187181335936241 0.851764837825497 USP6NL other 8.39969997337330e-11 1 1.94202654151705e-10 8.51558745809118 -0.187181335936241 0.0126192692510763 72.6401170731709 38.894136232018 1.86763672137737 0.0638594536574399 -228.791912195122 151.387109278034 -1.5113037912292 0.13291775931949 COMMD3 other 1 1 1 1.86763672137737 -1.5113037912292 0.00395025799046817 94.3667802362066 39.2529342239215 2.4040694562573 0.0174175002254446 -222.012214336695 167.06363819619 -1.32890805404331 0.185869724662886 MSRB2 other 1 1 1 2.4040694562573 -1.32890805404331 1.37976547917944e-06 29.530333142108 7.64700363603416 3.86168681847558 0.000164631094484725 -69.3135244222257 31.7841909138366 -2.18075472206063 0.0306994819252015 PDSS1 other 0.0124289274364484 1 1 3.86168681847558 -2.18075472206063 1.58804685628557e-20 544.59050962445 50.330203797552 10.8203517675988 9.75339860433718e-21 224.489025331988 252.840728232439 0.887867342027322 0.375970293599049 FAM171A1 other 2.24946837192851e-16 1 1.39951516573634e-16 10.8203517675988 0.887867342027322 1.01691798736161e-08 70.0252675386446 12.2358401287128 5.72296358909774 5.11792321432564e-08 -26.5042608006341 47.7133167223019 -0.555489800780201 0.579345354577656 MINDY3 other 0.000108322104013759 1 0.000603710222361852 5.72296358909774 -0.555489800780201 0.000190197935346875 186.473212183573 51.5675405114743 3.6160966827976 0.000401812417286643 -159.7868179876 204.92099274789 -0.779748408618058 0.436705439601836 RSU1 other 1 1 1 3.6160966827976 -0.779748408618058 0.685926564271647 -3.15118347079817 19.9500286196552 -0.157953832090925 0.874698769501465 66.3390646820802 87.6121103606841 0.757190580263089 0.450085197527411 ZEB1 other 1 1 1 -0.157953832090925 0.757190580263089 0.326555025714081 9.61136022089996 15.3073588785061 0.627891479985864 0.530993109835704 -37.242782264469 35.2477571926297 -1.05660005715928 0.292327656455631 FAM13C other 1 1 1 0.627891479985864 -1.05660005715928 0.0264657308808201 27.7866457725423 19.544495085579 1.42171213177284 0.157145058474374 -69.525163010195 41.7994038305502 -1.66330513449526 0.0982984175641295 NRBF2 other 1 1 1 1.42171213177284 -1.66330513449526 0.337704118028653 72.8108051076447 67.5524887556923 1.07784045338388 0.28275824139018 -41.443421668888 134.253516972245 -0.308695240195873 0.757962600157239 CDHR1 other 1 1 1 1.07784045338388 -0.308695240195873 5.57069922293322e-09 192.532738853503 37.3023014589886 5.16141715988168 7.71296271276401e-07 -148.896305732484 92.799100564387 -1.60450160429276 0.110721052511416 POLR3A essential 6.02749655921374e-05 1 0.00848040250268403 5.16141715988168 -1.60450160429276 3.67157152142739e-10 189.933042082739 33.6857998029364 5.63837115917855 7.78217963925762e-08 -128.156291012838 72.4594235779295 -1.76866285549467 0.0788920594660361 HERC4 other 4.23846216433578e-06 1 0.000909425512643645 5.63837115917855 -1.76866285549467 5.06197945613322e-07 175.920951978134 38.9858916337271 4.51242602403231 1.35958471343068e-05 -117.44298909855 87.3547936015963 -1.34443668465613 0.181012995758024 CAMK2G other 0.0047344693853214 1 0.136203196591486 4.51242602403231 -1.34443668465613 0.030861477588747 -428.376181646607 352.654857780129 -1.21471793793831 0.226345059758451 -1728.62073903614 651.568894796074 -2.65301298579816 0.00881951634561625 ADIRF other 1 1 1 -1.21471793793831 -2.65301298579816 6.14081001678369e-07 444.665423149854 123.549734993389 3.59908034747017 0.000429953850684154 -362.845931225541 227.836015979623 -1.59257494766759 0.113306085561755 GLUD1 other 0.00570112801958198 1 1 3.59908034747017 -1.59257494766759 0.0157069341629029 -10.2625656316847 5.49242074168367 -1.86849589904847 0.0635443918713499 -27.753108186945 9.5244500651481 -2.91388038124104 0.00408779049685526 ANKRD1 other 1 1 1 -1.86849589904847 -2.91388038124104 4.73311530029205e-07 50.2834251636742 38.1804518924333 1.31699397653383 0.189747542577323 -243.82692681662 66.2090223267921 -3.68268429660762 0.000316425100140541 RPP30 essential 0.00444202870932409 1 1 1.31699397653383 -3.68268429660762 3.43429729326789e-12 60.6005484934961 17.3804566119594 3.48670635337608 0.000635348832384417 -116.197064818589 30.7568285978403 -3.77792737794653 0.000224539700046181 FRA10AC1 other 4.28737674091563e-08 1 1 3.48670635337608 -3.77792737794653 0.00143700428617513 448.367184815347 138.871795663041 3.22864108348729 0.00152020741637994 34.0156455297042 234.841484647861 0.144845130666372 0.885022541890097 ADD3 other 1 1 1 3.22864108348729 0.144845130666372 0.114821724459155 14.9078463971453 9.95675256415973 1.49725990488179 0.136372439106624 -12.3340294391955 19.1764095652567 -0.643187630991253 0.521058922517256 HABP2 other 1 1 1 1.49725990488179 -0.643187630991253 4.42685442059853e-05 141.38376095837 65.7203043789214 2.15129498097267 0.0330433583092235 -388.311561940607 142.303689043081 -2.72875260333588 0.00711228568190988 DNAJB12 other 0.339229854250465 1 1 2.15129498097267 -2.72875260333588 4.35339954784012e-08 951.64748723989 214.752622233424 4.43136608690861 1.74938274247926e-05 -988.900981546917 471.803058227584 -2.09600375474866 0.0376858950299135 EIF4EBP2 other 0.000444830365798303 1 0.173433805089393 4.43136608690861 -2.09600375474866 0.000650503647968833 162.658042141081 43.853496492882 3.70912367654613 0.000288097608671262 33.0596518780268 96.3444056893763 0.343140337432921 0.731951920284057 NPFFR1 other 1 1 1 3.70912367654613 0.343140337432921 0.244953922565739 -431.815469987337 263.220264812427 -1.64050997477361 0.102940106803383 -555.783117124136 504.311964098837 -1.10206212957345 0.272154033242373 PLEKHS1 other 1 1 1 -1.64050997477361 -1.10206212957345 2.6164973303265e-06 203.909111552654 58.5823660008486 3.48072509651966 0.000650740942740035 -226.787113255748 112.827896093133 -2.01002696237949 0.0461744108945979 TCF7L2 other 0.0229142873234267 1 1 3.48072509651966 -2.01002696237949 0.0944367127536194 557.190869553325 255.927391395865 2.17714433189166 0.0309825694834235 390.891028884817 529.928004109531 0.737630443859358 0.461854263801431 MKI67 other 1 1 1 2.17714433189166 0.737630443859358 0.50746693782422 -44.7414797301193 51.6341901051419 -0.866508792701366 0.387550557634765 -102.639481575457 90.0390030359434 -1.13994466969479 0.256067820430144 CYP17A1 other 1 1 1 -0.866508792701366 -1.13994466969479 0.236198861949201 29.6017048595964 85.6326831833887 0.345682323140595 0.730047186913713 -171.675498125541 148.6994617879 -1.15451324477834 0.250055313459194 INA other 1 1 1 0.345682323140595 -1.15451324477834 0.221615700331466 -13.6283896442748 27.9571931105104 -0.487473459528069 0.626674576955945 -90.1912083772263 53.237715137493 -1.69412244955097 0.0924342355431846 FUOM other 1 1 1 -0.487473459528069 -1.69412244955097 1.43307696606314e-09 86.2420206208274 14.0015441650077 6.15946495646968 6.90589044185676e-09 25.6114791026803 26.2506354108561 0.975651777636154 0.330873212128867 LRRC27 other 1.60432966350768e-05 1 8.47007462693732e-05 6.15946495646968 0.975651777636154 0.0992953303564822 108.466265757878 50.3697135069659 2.15340247553478 0.032975696096089 123.649762919658 95.9169416128853 1.28913371131766 0.199447632607931 MTG1 other 1 1 1 2.15340247553478 1.28913371131766 0.307522719577842 18.5002715715245 22.5573339564953 0.820144419868265 0.413489280156575 -27.5781803787272 42.4622160385615 -0.64947576814367 0.517065530834275 NKX6-2 other 1 1 1 0.820144419868265 -0.64947576814367 0.103913334970077 21.7713912976748 10.2695605726615 2.11999249078216 0.0357456485597287 26.3374517176988 19.5558952643583 1.34677811277197 0.18019725176101 PAOX other 1 1 1 2.11999249078216 1.34677811277197 0.0213492157616724 -53.6508408313177 95.3251264772694 -0.56281950849665 0.574370959599793 -422.177911671297 163.683215071671 -2.57923765418732 0.0108314614346418 GSTO1 other 1 1 1 -0.56281950849665 -2.57923765418732 5.23511465105654e-09 35.2709435605236 12.9878373462172 2.71569027393129 0.00736475481335121 -73.9911100489337 22.506580708283 -3.2875322559194 0.00125046517458367 TAF5 other 5.67800535053592e-05 1 1 2.71569027393129 -3.2875322559194 2.8038076288106e-13 583.364737026511 100.020351808033 5.83246035912921 3.1097535677176e-08 -260.597247634992 174.714483923473 -1.49156064101209 0.137859963495067 PPRC1 essential 3.61607069887703e-09 1 0.000370464942522197 5.83246035912921 -1.49156064101209 0.0374773108998941 60.1551124342693 51.1832426891739 1.17528920157677 0.241681252473495 -107.38082582746 87.8869824857283 -1.22180581003447 0.223635993515949 ITPRIP other 1 1 1 1.17528920157677 -1.22180581003447 1.74893836466278e-13 208.615202831168 61.7850241395289 3.37646874362391 0.000926884925394053 -462.496560186815 107.288473215593 -4.31077585806859 2.87147075453013e-05 CNNM2 other 2.2680232712947e-09 0.414783950491877 1 3.37646874362391 -4.31077585806859 2.783023798429e-13 496.18733022252 91.8096666989619 5.40452163767772 2.40710339891809e-07 -326.298576472037 159.096670082844 -2.0509453548093 0.0419560526021476 PDCD11 essential 3.59010069997341e-09 1 0.00273519159219063 5.40452163767772 -2.0509453548093 0.384263426240827 -117.443015636934 94.7843931019079 -1.23905436109787 0.217186353415739 -0.864465168629595 179.629938061907 -0.00481247824252809 0.996166361362597 ADAM12 other 1 1 1 -1.23905436109787 -0.00481247824252809 0.236621195774883 195.141312582268 136.25063810073 1.43222310957545 0.154093549518957 -26.7244012840786 244.47308870999 -0.109314286595286 0.913094610196757 RGS10 other 1 1 1 1.43222310957545 -0.109314286595286 8.04615633105982e-09 95.2812744711456 31.6105008737875 3.01422855814841 0.00301663720615011 -144.218222915822 50.3922554382114 -2.86191244392019 0.00480099831564285 BTBD10 other 8.62789343379545e-05 1 1 3.01422855814841 -2.86191244392019 0.238574970915567 -93.8183422243871 110.97244788115 -0.845420138202823 0.399171120926589 -292.178804943812 174.075677428203 -1.67845852597254 0.0952597109341647 ADM other 1 1 1 -0.845420138202823 -1.67845852597254 0.443249447408791 9.48399763196363 21.9653896360703 0.431770061405583 0.666508536448112 43.4739455593276 35.2668007486066 1.23271588679745 0.21954821845885 GAS2 other 1 1 1 0.431770061405583 1.23271588679745 0.0957762102440091 25.1583226884151 11.6373607938696 2.16185809944709 0.0321836498525641 17.2761404392257 19.7508980760788 0.8747015134542 0.383107328652515 SLC5A12 other 1 1 1 2.16185809944709 0.8747015134542 5.5259171415702e-09 178.518470523763 39.5890352945783 4.50929074667832 1.2816715310617e-05 -114.332154546253 67.3643739460182 -1.69721987823819 0.0916751503611581 LIN7C other 5.98014753060728e-05 1 0.128807988871701 4.50929074667832 -1.69721987823819 0.210885536394135 33.9984605685633 19.366592229618 1.75552106253202 0.0811585041924323 20.5865820223732 32.6273244023787 0.630961392006521 0.529001079972246 LRRC4C other 1 1 1 1.75552106253202 0.630961392006521 0.0160667483558664 19.6963411572737 17.7675617927325 1.10855622099652 0.269338799583557 -50.9467909292499 28.9109214208348 -1.76219879635295 0.0800069185285562 IMMP1L other 1 1 1 1.10855622099652 -1.76219879635295 0.525512661013547 -0.0768692658164637 1.29757063869386 -0.0592409103013001 0.95283604532481 -8.43521022739093 7.51690820215789 -1.12216485828168 0.263516572223506 SAA4 other 1 1 1 -0.0592409103013001 -1.12216485828168 1.41382053283079e-14 212.440387906446 48.9775587760246 4.33750462896568 2.60437088063161e-05 -239.772425841415 76.3629261677928 -3.13990620677057 0.00202871443321244 PGAP2 other 1.88052269071824e-10 1 0.254004291988001 4.33750462896568 -3.13990620677057 0.128470781722176 12.6373976214518 34.7627702107731 0.36353252473347 0.716712234459629 111.538118478627 60.0952657587515 1.85602171935456 0.0653866141673685 SYT8 other 1 1 1 0.36353252473347 1.85602171935456 0.00183707112530222 6.38234851273126 6.66290484169461 0.957892790662758 0.33960854285276 -21.8640685470829 10.5861891511356 -2.06533892743996 0.0405561913202456 ZNF214 other 1 1 1 0.957892790662758 -2.06533892743996 0.00526617079785766 5.09087563154548 4.95010121223444 1.02843869514488 0.305345718613996 -13.6935010762762 7.86484408753036 -1.74110267462099 0.0836497768619584 ZNF215 other 1 1 1 1.02843869514488 -1.74110267462099 6.13679673628873e-06 -122.369080779944 125.530215980186 -0.974817734713844 0.331199505087808 -1055.25666202414 219.434368093139 -4.8089853526328 3.61765158546463e-06 HSD17B12 other 0.0517086492999689 0.0526657717811941 1 -0.974817734713844 -4.8089853526328 1.33471526290498e-06 59.8790773532154 23.3135414561946 2.56842477003016 0.0111545170852572 -120.27885212799 39.4197059590798 -3.05123666454659 0.00267916709871527 APIP other 0.0120404663866658 1 1 2.56842477003016 -3.05123666454659 0.544863569721783 11.4361440327598 10.4261001881834 1.09687647599254 0.274396575152534 6.93901510677111 17.5807445296776 0.394694041259603 0.693611272490937 PAMR1 other 1 1 1 1.09687647599254 0.394694041259603 5.54844228860852e-49 417.617691998493 17.9432616189758 23.27434670834 2.83485371034778e-49 -37.0248279185199 117.558026539419 -0.314949382942429 0.753282790787822 DGKZ other 8.09406761062212e-45 1 4.13491762191328e-45 23.27434670834 -0.314949382942429 0.000370979287813505 403.521688657343 359.261089148229 1.12319897936638 0.263100945413608 -1642.5821252619 582.710209178576 -2.8188662209598 0.00545280461904039 EIF3M essential 1 1 1 1.12319897936638 -2.8188662209598 0.00025771697359428 4973.15628889667 1290.38428193549 3.85401183083017 0.000172691297705855 -1913.14736539751 4659.39483207886 -0.41059996723736 0.681959723899179 SERPING1 other 1 1 1 3.85401183083017 -0.41059996723736 0.835481430274703 4.07241566399636 13.198433170055 0.308552963183233 0.758095488330856 27.7716209746911 47.6576723422667 0.582731375868331 0.560960940026712 SLC43A1 other 1 1 1 0.308552963183233 0.582731375868331 0.00234441960038216 109.417938417247 72.636043577487 1.50638626538794 0.134128617434127 -328.730912155801 144.010497093944 -2.28268715676578 0.0238930344448389 PTPRJ other 1 1 1 1.50638626538794 -2.28268715676578 3.0837511423296e-09 274.25481568125 57.7128470718026 4.75205833009832 4.7731791887502e-06 -269.853872503969 114.836205307122 -2.34990238298332 0.0201171354167612 C11orf49 other 3.39181788144833e-05 1 0.0498510834473071 4.75205833009832 -2.34990238298332 8.21964721821105e-14 339.205307472561 58.3281233124673 5.8154675345102 3.7096992653108e-08 -398.857013982859 115.86973906778 -3.44228801403913 0.000754035793391667 ARFGAP2 other 1.07480107025328e-09 1 0.000440526787755657 5.8154675345102 -3.44228801403913 2.12638010791511e-05 286.79258064516 130.903875191164 2.19086394674218 0.0300366830372888 -793.174265232975 263.43012222431 -3.01094748973919 0.0030664281523642 CELF1 other 0.169685132611626 1 1 2.19086394674218 -3.01094748973919 0.000153048315610778 97.4585935304319 33.0645585735304 2.94752441087938 0.00369553787247756 -201.581417985646 112.006346972939 -1.79973209941708 0.0738354643447239 HIKESHI other 1 1 1 2.94752441087938 -1.79973209941708 0.234240218178573 -19.7371866495754 13.0427168326072 -1.51327264885731 0.132233737182392 -58.001727411693 44.1822643352113 -1.3127830427982 0.191184037086232 CCDC81 other 1 1 1 -1.51327264885731 -1.3127830427982 0.0610557812810682 193.471664275466 149.62478274467 1.29304558193157 0.197919228721191 -513.568448110952 410.884059211657 -1.24991086073359 0.213216013421829 SESN3 other 1 1 1 1.29304558193157 -1.24991086073359 0.00537536142794065 165.490554758488 82.8115055076577 1.99840050901122 0.04742202588556 -339.161704925873 227.408367171895 -1.49142139818235 0.137883284002775 ENDOD1 other 1 1 1 1.99840050901122 -1.49142139818235 4.14229409977839e-08 80.372617192183 18.6123876999898 4.31823248514361 2.79578357813147e-05 -101.377415085814 50.1184087015457 -2.02275805861105 0.04481729178719 CCDC82 other 0.000423880955230323 1 0.271694248122816 4.31823248514361 -2.02275805861105 0.00145788345291027 109.677199686459 30.7214501897404 3.57005281355782 0.000477255205482707 7.83556053000504 110.556725075081 0.0708736671123697 0.943590856237203 KLHL35 other 1 1 1 3.57005281355782 0.0708736671123697 0.137009709192622 192.922422575522 124.22405227702 1.55301987851197 0.1224710675098 -320.020582688518 445.645556668874 -0.718105628788534 0.473780161183249 TENM4 other 1 1 1 1.55301987851197 -0.718105628788534 0.0259789047341883 1194.35234175975 457.778438271618 2.60901834142545 0.00998118197166287 2475.43132998688 1647.39895521588 1.50263014441605 0.134995633440692 SERPINH1 other 1 1 1 2.60901834142545 1.50263014441605 0.00146251235734913 487.031774683293 132.315444152831 3.68083845239371 0.000322311351013694 546.357278835999 480.023036754226 1.13818970549894 0.256832093227171 CAPN5 other 1 1 1 3.68083845239371 1.13818970549894 3.90232514461592e-10 169.956374821297 23.9652032979747 7.09179774976747 5.06237968410359e-11 127.871644355875 88.8158036513398 1.43973976588508 0.152052881982003 INTS4 essential 4.50055158928554e-06 1 6.65044819100688e-07 7.09179774976747 1.43973976588508 4.92999874610136e-07 365.903456495829 69.1364800614243 5.29248026759161 4.17652729305065e-07 -186.30274135876 257.745832685278 -0.722815726709523 0.470911164703435 PAK1 other 0.00461743682559853 1 0.00467603995729951 5.29248026759161 -0.722815726709523 0.124251889493527 5413.43366647071 3357.28720842368 1.61244282374412 0.108926436107489 -9489.21575543796 12081.8085281578 -0.785413519285826 0.433425720771144 RPS3 essential 1 1 1 1.61244282374412 -0.785413519285826 0.0179227969682878 20.0709843573947 13.5460174454565 1.48168894940606 0.140466348888016 -49.0969480579659 35.2850326786775 -1.39143836155875 0.166099259659861 ZC3H12C other 1 1 1 1.48168894940606 -1.39143836155875 2.86135155025669e-10 84.5171470518112 15.4198790004817 5.48105124879196 1.71928072735188e-07 -46.4486717779479 40.8198520468662 -1.13789417278189 0.256955104346437 TTC12 other 3.31945393345279e-06 1 0.00197184306619987 5.48105124879196 -1.13789417278189 0.489672583767354 82.3838404485194 153.741066270558 0.535860993077398 0.592843062749074 -260.331279565496 402.672884164797 -0.64650809578465 0.518931800920081 NCAM1 other 1 1 1 0.535860993077398 -0.64650809578465 0.349808018009765 3.55434605297826 11.7279449331131 0.303066400230342 0.762253646188877 -33.1847401904811 31.046480777736 -1.06887284352945 0.286821496548702 DRD2 other 1 1 1 0.303066400230342 -1.06887284352945 0.00492362834754947 1.31681609746079 24.9510639018331 0.0527759498609613 0.957980644251777 -174.661989825018 61.8625312759688 -2.82338899205159 0.00539751956732963 C11orf52 other 1 1 1 0.0527759498609613 -2.82338899205159 2.33934356193757e-13 140.474926728719 20.4883726557088 6.85632427178536 1.57914703687233e-10 -44.6966407935841 54.2592792286646 -0.823760312134249 0.411341472243842 NPAT essential 3.02383548816051e-09 1 2.04562707156441e-06 6.85632427178536 -0.823760312134249 1.13280080281228e-13 302.024662630037 41.0917722261715 7.350003328347 1.06662946688221e-11 -12.6422251924375 108.823183797337 -0.116172168018732 0.907666472477303 ATM ts 1.47535976558271e-09 1 1.42117710167385e-07 7.350003328347 -0.116172168018732 1.62836180504703e-16 246.537635439017 32.6397058747119 7.55330444414408 3.51039552884024e-12 -153.807961239794 88.8763503464333 -1.73058367766297 0.0855291564989345 AASDHPPT essential 2.23378672416351e-12 1 4.72218406539588e-08 7.55330444414408 -1.73058367766297 5.26626190298987e-09 432.482421736859 70.134198189912 6.16649841159897 7.93151247272713e-09 -46.8548997597518 191.42824901796 -0.2447648139714 0.807018624877399 GLB1L2 other 5.70915452903132e-05 1 9.6938945441671e-05 6.16649841159897 -0.2447648139714 1.4399480491155e-13 89.9682344786611 12.1218364341026 7.42199706849298 7.99449971965998e-12 -50.7673895105128 38.9376742707184 -1.30381155170047 0.194295222701464 SLX4IP other 1.8713564846305e-09 1 1.06758549256339e-07 7.42199706849298 -1.30381155170047 0.00553814839833925 317.038693867672 134.135815604494 2.36356481256636 0.0193648407662375 -713.259417995288 482.803612037957 -1.47732825565359 0.141656635366646 LAMTOR1 other 1 1 1 2.36356481256636 -1.47732825565359 0.0149573000680078 10.0817580156064 4.26081483933585 2.36615727173395 0.0192181248000375 -15.0552874808688 16.3625374781729 -0.920107135030372 0.358955801574813 P4HA3 other 1 1 1 2.36615727173395 -0.920107135030372 0.0765929253247738 14.2747907746205 6.81407090848372 2.09489906494045 0.0378495489367507 -0.550381349746981 19.0661912114255 -0.0288668745447787 0.977008882077358 GRIK4 other 1 1 1 2.09489906494045 -0.0288668745447787 7.38284375322895e-10 2091.28766771114 347.701668702738 6.01460348324947 1.26154648503728e-08 -1133.05581499449 967.904520390301 -1.17062767155752 0.243556741757908 ST14 other 8.3906019255447e-06 1 0.000152836356662266 6.01460348324947 -1.17062767155752 1.91638179419354e-11 1831.39559724557 264.852519986842 6.91477505041883 1.46900827097589e-10 -568.518006083987 738.208530206828 -0.7701319922769 0.442500933545391 HYOU1 essential 2.33242828171296e-07 1 1.90427542166605e-06 6.91477505041883 -0.7701319922769 4.76850481786129e-06 118.826145002781 23.5523782281132 5.04518668356578 1.31792784014515e-06 249.739041349898 87.4261175687322 2.85657247851089 0.00490339751624216 ADAM33 other 0.0406133555337246 1 0.0142902915706939 5.04518668356578 2.85657247851089 1.83238040133988e-16 209.022168994426 26.9531715414004 7.75501200937951 1.12645081325904e-12 -194.305816668533 83.7570213592244 -2.31987496111135 0.0216609193833599 KAT14 other 2.51237676827711e-12 1 1.52814317326722e-08 7.75501200937951 -2.31987496111135 0.00359242083571776 99.0103632843635 80.224957253062 1.23415912796369 0.219073701016098 -700.943856052843 265.093185049449 -2.6441413645624 0.00906088643254025 TKFC other 1 1 1 1.23415912796369 -2.6441413645624 0.00429345791938219 55.2233392769069 35.2007271527028 1.56881245769 0.118798760103014 -272.190075496036 116.271627896569 -2.34098447248168 0.0205493260994052 TMEM138 other 1 1 1 1.56881245769 -2.34098447248168 0.413238443745 -18.4808647385334 14.2300291926362 -1.29872289707578 0.196220761914721 -30.9352887330801 32.0440822883324 -0.965397868309182 0.336046616676736 PLCH2 other 1 1 1 -1.29872289707578 -0.965397868309182 6.64786207596567e-05 455.705224022154 131.639417791746 3.46176875943862 0.000699311810691767 -741.264228536745 434.818557457772 -1.70476677184766 0.0903082065615888 CPSF7 other 0.498722612938945 1 1 3.46176875943862 -1.70476677184766 3.67446218661115e-13 728.094269209953 103.363606667172 7.04400990528898 5.9451763271953e-11 -644.621047818324 289.303756884992 -2.22818070100135 0.0273268776535291 EI24 other 4.72535837198194e-09 1 7.79709875311664e-07 7.04400990528898 -2.22818070100135 9.13453716790756e-10 20.5145733044353 3.41392696857152 6.00908381851507 1.34093394594001e-08 -12.7961926944668 9.05880462061661 -1.41256967451802 0.159840040375933 CCDC15 other 1.03339018980538e-05 1 0.000162306644816579 6.00908381851507 -1.41256967451802 1.71640333358037e-07 154.769786446341 29.4409752396636 5.25695175470379 4.84912890780511e-07 -74.7887686803019 81.868205364189 -0.913526421491783 0.362403061922992 CHEK1 essential 0.00167520965357444 1 0.00541017312243817 5.25695175470379 -0.913526421491783 0.237570737801105 10.0615028202479 6.41262102035703 1.56901566275434 0.118710123444302 -3.25941939647563 17.9482451559826 -0.18160100712627 0.856136223221972 FEZ1 other 1 1 1 1.56901566275434 -0.18160100712627 0.251964431304586 -30.1727393045903 18.2682332264851 -1.65165065118866 0.100815503760572 -13.608032184835 48.277794822573 -0.2818693818731 0.778454042274823 ESAM other 1 1 1 -1.65165065118866 -0.2818693818731 0.280816076364744 12.9799641285413 14.9390717241279 0.868860151971661 0.38627570521848 -41.6155995003209 42.4281530912435 -0.980848716436581 0.328205745307165 KIRREL3 other 1 1 1 0.868860151971661 -0.980848716436581 0.000564799618432389 91.6333267687461 124.871817377217 0.733819117022516 0.464174708225484 -1162.75825907144 347.952690277723 -3.34171366269181 0.00104505200391133 MPZL2 other 1 1 1 0.733819117022516 -3.34171366269181 0.0612022310571432 11.926849982768 10.133642289547 1.17695589028939 0.241029013167657 -42.0006154300626 28.2371809029449 -1.48742240149342 0.138947947930877 SCN2B other 1 1 1 1.17695589028939 -1.48742240149342 1.8053332488786e-13 450.68269650655 57.5836264557528 7.82657717559442 8.12435292839942e-13 82.2237991266372 155.96624429972 0.527189710156947 0.598835542469947 SIDT2 other 2.33953135722178e-09 1 1.10499324179161e-08 7.82657717559442 0.527189710156947 7.89738581222647e-11 168.865618169666 30.3010659372695 5.57292665938746 1.09310684299557e-07 -212.347563508932 84.8775541764972 -2.50181058548612 0.0134010160156246 TMEM25 other 9.38920199215605e-07 1 0.00126712945240046 5.57292665938746 -2.50181058548612 0.15644427502637 918.880240174671 583.526657850864 1.57470139163636 0.117418253689896 -512.386189956334 1580.49200572145 -0.324194104178619 0.746239722066629 TAGLN other 1 1 1 1.57470139163636 -0.324194104178619 0.228882589550926 9.91256385374517 10.3600155888061 0.956809743071781 0.340153262331041 76.1596938682096 45.4309526181388 1.67638337915463 0.0956789394864473 JPH2 other 1 1 1 0.956809743071781 1.67638337915463 0.200805740469169 9.63229558434322 6.11617486586203 1.57488884729355 0.117388896756649 -6.97370803733111 28.1411930272489 -0.247811385628837 0.804619249044527 KIAA1755 other 1 1 1 1.57488884729355 -0.247811385628837 0.0686356078154935 33.5136970877892 16.0597681804312 2.08681076284934 0.0385423159728725 -22.0685428835345 69.8089162710007 -0.316127853895678 0.752330766813409 CDH22 other 1 1 1 2.08681076284934 -0.316127853895678 1.00629185619607e-11 277.771427976978 40.3897126689489 6.87728160518768 2.02296246544083e-10 -211.302135970809 149.901613047843 -1.40960548505485 0.160938867551241 LSM14B other 1.23713520800744e-07 1 2.61265602411683e-06 6.87728160518768 -1.40960548505485 1.44594028741745e-05 218.684431478583 63.3381286367707 3.45265065743711 0.000773474845764142 -364.204870499501 220.702496966309 -1.65020729491383 0.101582627007769 YTHDF1 other 0.117439270144046 1 1 3.45265065743711 -1.65020729491383 0.00292335590967286 85.4812030075189 38.9243826130824 2.19608372102449 0.0300249661649268 -194.375939849624 132.885025841643 -1.46273772096232 0.146175298683655 CABLES2 other 1 1 1 2.19608372102449 -1.46273772096232 0.00103039575196684 329.805018125105 89.5469964608418 3.68303830569377 0.000317854996837938 10.8246501433146 268.601398933651 0.0403000512517379 0.967905775306023 ORAOV1 essential 1 1 1 3.68303830569377 0.0403000512517379 0.0140250245629593 89.2147716229353 43.895454906092 2.03243756816731 0.043897583174609 -209.741788143829 138.240592607806 -1.51722286621611 0.13134354254641 TRPT1 other 1 1 1 2.03243756816731 -1.51722286621611 0.216025506662549 -55.9344461113528 50.8733138719411 -1.09948501196819 0.273353946028595 -259.984352873547 160.105623471114 -1.62383023929483 0.106554468895429 NUDT22 other 1 1 1 -1.09948501196819 -1.62383023929483 0.260425767575486 1.79837024022296 36.9747400612365 0.0486378061683342 0.961273515017743 -191.24672079004 121.766470505474 -1.57060248191593 0.118410489649316 FERMT3 other 1 1 1 0.0486378061683342 -1.57060248191593 0.0664107816340213 105.118128939199 60.2220730017956 1.74550831114806 0.0830146832082105 -186.093631432065 180.699517237973 -1.02985129277899 0.304794602675991 PLCB3 other 1 1 1 1.74550831114806 -1.02985129277899 0.0495208359762135 226.411305335198 103.655004908179 2.18427759986853 0.030560038152418 -159.514116220329 315.026489705582 -0.506351438475564 0.613384327440783 MRPL49 other 1 1 1 2.18427759986853 -0.506351438475564 0.417170993478298 25.6762190126866 19.9762564433485 1.28533687407863 0.200766964400392 3.26972892788887 62.6670425357414 0.0521762124967685 0.958461614358742 CDC42EP2 other 1 1 1 1.28533687407863 0.0521762124967685 0.395625248960071 -196.493530870302 693.642858533503 -0.283277667250446 0.777370835206916 -2871.66792315833 2108.10732223421 -1.36220195853923 0.175261115564567 FAU essential 1 1 1 -0.283277667250446 -1.36220195853923 0.0032649798637203 400.851622368236 121.828933806223 3.29028261058096 0.00126046912212582 -26.4286048725663 369.998483909908 -0.0714289545008013 0.943156167397401 TM7SF2 other 1 1 1 3.29028261058096 -0.0714289545008013 2.75734880703838e-05 406.589811621118 129.97402606741 3.12823895606838 0.00213148095624142 -1006.46855929955 394.735397332615 -2.54972968246744 0.0118340315137637 VPS51 essential 0.217389379946906 1 1 3.12823895606838 -2.54972968246744 0.000366256994139229 18.2945794540004 6.86978740711654 2.66304884996131 0.00856673953141537 -23.0472959264186 14.6931580427628 -1.5685733359256 0.118799841296343 TBX6 other 1 1 1 2.66304884996131 -1.5685733359256 1.14646548463179e-05 586.89644153385 178.223681433268 3.29303287202942 0.00122947344529822 -695.702394102664 381.186281768966 -1.82509819313048 0.0699238348221209 PPP4C essential 0.0941821395625019 1 1 3.29303287202942 -1.82509819313048 0.000280630159874472 -2350.62766293199 2264.10652621261 -1.03821425172256 0.300797683889907 -19661.2007146239 4842.48973713959 -4.06014298054818 7.78238403171649e-05 ALDOA essential 1 1 1 -1.03821425172256 -4.06014298054818 0.063976590448461 9.55629635474202 4.81394454382533 1.98512805200457 0.0489061716209676 21.0215627042991 10.2961043478942 2.04170062715016 0.0428878168361337 FAM57B other 1 1 1 1.98512805200457 2.04170062715016 0.0555752002643493 5.68463408524161 17.5616877971047 0.323695202358557 0.746610841661741 -75.2183760148483 37.5799469939132 -2.00155620302049 0.0471003557652797 DOC2A other 1 1 1 0.323695202358557 -2.00155620302049 9.04286563758023e-06 109.055470787169 29.3245126557551 3.71891843753339 0.00028029863107645 -82.7772286810674 62.7510091260874 -1.31913780883971 0.189093863848744 HIRIP3 other 0.0750467419262783 1 1 3.71891843753339 -1.31913780883971 0.00533568067453299 168.249860511722 67.0532865589196 2.50919632945778 0.0131418976699373 -110.633424807279 143.48614915403 -0.771039054707053 0.441872870526095 TAOK2 other 1 1 1 2.50919632945778 -0.771039054707053 2.32721434613464e-05 45.9285108345391 131.888351086608 0.348237812180842 0.728140275541961 -1158.12647316701 282.225563978336 -4.10354914998383 6.5950276742357e-05 TMEM219 other 0.185083356948088 0.947573576234185 1 0.348237812180842 -4.10354914998383 1.50979764711765e-13 803.859663360823 95.8826445273793 8.38378694416673 3.33679073717885e-14 88.4563795907011 616.650316248099 0.143446581084882 0.886128747665885 HMGA2 other 1.96152910313524e-09 1 4.61044376156001e-10 8.38378694416673 0.143446581084882 0.801366902368647 0.474849866409389 6.31209149770492 0.0752286095000436 0.940129206488582 -9.76151247964495 17.617494407818 -0.554080634492107 0.580317049107386 CNTN5 other 1 1 1 0.0752286095000436 -0.554080634492107 0.000303265352193785 12.3391048431698 3.6506026556582 3.38001859064145 0.00091713002503949 -20.283543691238 16.178682082819 -1.25372039498682 0.211831309345325 KLRF1 other 1 1 1 3.38001859064145 -1.25372039498682 0.851740831736592 -1.54951749059682 2.78154043960758 -0.557071710528654 0.578281947653473 -0.817175878269455 12.3409184879082 -0.066216779494179 0.947290569640746 CLEC1A other 1 1 1 -0.557071710528654 -0.066216779494179 0.844572516928642 7.1914265962645 39.3357760716113 0.182821525706583 0.855175438196523 -72.0763060346371 163.945345942327 -0.439636182536051 0.660809058948089 MKX other 1 1 1 0.182821525706583 -0.439636182536051 0.000272592157215349 126.659383015559 45.4752505740475 2.78523771538805 0.00600337787439581 -361.548066261494 192.935148342399 -1.87393572072135 0.0627857239525539 MPP7 other 1 1 1 2.78523771538805 -1.87393572072135 0.000345865683634214 958.204832833264 240.606033201146 3.98246386462058 0.000105432266679827 524.872990784401 1102.46276460993 0.476091354405161 0.634692888889925 ITGB1 other 1 1 0.961964001186741 3.98246386462058 0.476091354405161 0.397707479800458 -3.55430364228798 11.8757838168475 -0.299290025576728 0.765138640056234 -37.242192792851 27.7662980536303 -1.34127324863106 0.181886399642728 FXYD4 other 1 1 1 -0.299290025576728 -1.34127324863106 0.733149892309601 1.95478586935032 14.3954987021745 0.135791465776385 0.892164634452325 -19.9117584369452 29.9204821829497 -0.665489222907377 0.506739636247372 PCDH15 other 1 1 1 0.135791465776385 -0.665489222907377 0.00011009113364101 109.182779697704 33.657975804437 3.24389025448497 0.0014479337070184 -83.0122492651674 69.2490441087205 -1.19874938829248 0.232478798617006 CTF1 other 0.803885457846652 1 1 3.24389025448497 -1.19874938829248 3.76900525437518e-08 161.255738880918 49.1287914244364 3.28230624457638 0.0012723223961115 -446.432867049259 134.912391345506 -3.30905754910206 0.00116407660625251 CWC15 other 0.000386888389361612 1 1 3.28230624457638 -3.30905754910206 0.00961354576336466 335.5208554729 121.908940959286 2.75222516767621 0.00663994699387319 -103.507742523152 263.393517323489 -0.392977562906486 0.694886645540929 ARID5B other 1 1 1 2.75222516767621 -0.392977562906486 1.52526868213617e-08 127.91756482766 23.0776662975895 5.5429159594452 1.30504406447874e-07 -33.9910977401642 42.2988986523922 -0.803592973412841 0.422903690424652 DCUN1D2 other 0.000160824329844438 1 0.00150732589447294 5.5429159594452 -0.803592973412841 8.94484048168813e-06 161.38512431971 40.8861366275587 3.94718448920239 0.000121182543410109 -101.47295666664 74.9399236125365 -1.35405738056643 0.177754536850366 TMCO3 other 0.0742779553599382 1 1 3.94718448920239 -1.35405738056643 4.62133128721511e-07 89.2222811808403 16.116584868007 5.53605381732919 1.3031843359623e-07 26.3617456352647 44.3645409354435 0.594207560349259 0.553245204221405 TMEM218 other 0.00434081647808115 1 0.00150530822647006 5.53605381732919 0.594207560349259 9.59332821020157e-07 36.3455103179029 6.91674684004625 5.25471166697492 4.93402987833594e-07 2.85796916323335 19.3691530749015 0.147552613796867 0.88289139810345 TIRAP other 0.00876926131694526 1 0.00550193671733241 5.25471166697492 0.147552613796867 0.000357276948948951 18.488543386904 14.9024763582262 1.24063564621583 0.216703463860558 -61.8110336864436 24.5393140484993 -2.51885743685748 0.012836281198731 EEF1AKMT1 other 1 1 1 1.24063564621583 -2.51885743685748 0.0027334425896055 116.661452532916 37.5195129835548 3.1093541268526 0.00225209376310173 25.8605525436569 61.0543066551343 0.42356639458262 0.672501165350505 LATS2 other 1 1 1 3.1093541268526 0.42356639458262 1.11748219748066e-07 499.040549993442 212.752179488492 2.34564248034147 0.0203124316664568 -1109.78395925327 343.808412955304 -3.22791391203549 0.00153367813203508 SAP18 essential 0.00110742485770334 1 1 2.34564248034147 -3.22791391203549 7.34888501821534e-05 292.895785758771 66.4600756702776 4.40709377479328 1.98475877880317e-05 207.197483449819 112.197152834428 1.84672675032659 0.0667572259261111 ADGRL3 other 0.548814733160322 1 0.195855996292297 4.40709377479328 1.84672675032659 1.76102676446095e-13 73.0140224371326 10.7090130958356 6.81799730598197 2.07482080187525e-10 7.65093580538459 24.1323498132944 0.317040647287887 0.751650680846465 KIAA1328 other 2.28317120012362e-09 1 2.67755624482001e-06 6.81799730598197 0.317040647287887 3.72638918932237e-10 230.177749360613 51.3193422178427 4.48520459174134 1.45840858410959e-05 -188.799072890026 86.4362397793982 -2.18425828531964 0.0305282452139926 FAM124A other 4.30062576339694e-06 1 0.145622097123342 4.48520459174134 -2.18425828531964 0.00789842170537673 -95.3382174539389 30.7742456027031 -3.09798715083903 0.00231883049476343 -19.9004852528619 79.3746325941445 -0.250715935336876 0.802370112979242 HNMT other 1 1 1 -3.09798715083903 -0.250715935336876 0.0645422760381737 -1815.5946541747 945.390161582885 -1.92047128048679 0.0566585467995425 -4516.28924051974 2295.53852393154 -1.96742036495417 0.0509430465566046 LYPD1 other 1 1 1 -1.92047128048679 -1.96742036495417 0.550951717058062 183.920879599095 246.432144049227 0.746334778316725 0.456581299816779 -363.949726995179 697.40725343441 -0.52186111515602 0.602502498024847 LYPD6B other 1 1 1 0.746334778316725 -0.52186111515602 0.0689335822069482 -27.2743181040055 61.2979696116675 -0.444946517426151 0.656991368082451 -243.814784874653 109.448792614378 -2.22766079963703 0.0273719878555977 ADRA2A other 1 1 1 -0.444946517426151 -2.22766079963703 0.207892160729915 49.5007139553124 43.1431762139277 1.14735905650202 0.253001153454564 -16.9705367737264 66.6384406195143 -0.254665874770737 0.799318739279348 GPM6A other 1 1 1 1.14735905650202 -0.254665874770737 0.00685975572747617 4.81784183659545 5.46471363057509 0.881627503706618 0.379334642389484 -15.1795102776185 8.65588657722836 -1.75366326050902 0.0814521657914632 WDR17 other 1 1 1 0.881627503706618 -1.75366326050902 8.08153678993814e-05 69.4552621995629 25.5948496739107 2.71364212271033 0.00740337548694804 -37.6497997086671 40.6556502066024 -0.926065614922888 0.355842303536131 VEGFC other 0.600213948179986 1 1 2.71364212271033 -0.926065614922888 2.0147188161017e-06 19.043026337137 4.21360497488837 4.51941424282222 1.23898271531853e-05 8.93439511113526 7.62752851060092 1.17133552483193 0.243296830067778 CCDC102B other 0.0178665264611899 1 0.124716000123963 4.51941424282222 1.17133552483193 0.569258421625494 -4.26804610096374 4.11967919341065 -1.03601418959768 0.301851788565124 -4.01355640383059 7.12012007546705 -0.563692235705353 0.573799790894848 CD226 other 1 1 1 -1.03601418959768 -0.563692235705353 0.647380710362088 1.69492281338374 1.84653524521926 0.917893561886759 0.360091540263123 1.1407705484659 6.50887846255893 0.175263765490163 0.861099660576592 DLG2 other 1 1 1 0.917893561886759 0.175263765490163 0.180544389077112 -4.31133494942738 2.40308301773836 -1.79408489744352 0.0748832931235908 -7.22954108501212 9.38411621870713 -0.770401912819462 0.442314926129369 RGS18 other 1 1 1 -1.79408489744352 -0.770401912819462 1.40710774498058e-05 1167.68617734389 239.298981675242 4.87961197815952 2.58887575779165e-06 1168.45056235378 814.0730128876 1.43531420874544 0.153186794502048 PRSS23 other 0.114411930744371 1 0.0275430491871453 4.87961197815952 1.43531420874544 1.71165506233053e-11 355.731793087802 47.989896434252 7.41263931617707 7.86838584203284e-12 -93.1027841930439 192.433349863516 -0.483818341566456 0.629206546888466 MTMR12 other 2.08719218300585e-07 1 1.05098029692033e-07 7.41263931617707 -0.483818341566456 0.00928063771409865 22.9306021869705 7.87028412616166 2.91356726382302 0.00410206310397526 -3.4935314954566 26.2693921209551 -0.132988669070489 0.894374837609218 PPP1R1C other 1 1 1 2.91356726382302 -0.132988669070489 2.08886420412669e-15 1453.4673799016 175.376934103665 8.2876769817544 5.81979962319658e-14 -1378.79462089423 715.870310187641 -1.9260396768415 0.0559782633752481 CCT5 essential 2.82101110767309e-11 1 8.01793794087793e-10 8.2876769817544 -1.9260396768415 1.0214367149359e-08 54.7080085190276 10.2671444353613 5.32845416400361 3.53674252012938e-07 -93.5677497829548 41.9094102040744 -2.23261910218574 0.0270453246556382 FAM173B other 0.000108772795773524 1 0.00397565226687744 5.32845416400361 -2.23261910218574 0.0125696052264303 201.085167021747 80.9733078545146 2.48335127154542 0.0140729924819698 -57.822229368493 153.455962512054 -0.376800147885756 0.706834167714895 DOCK1 other 1 1 1 2.48335127154542 -0.376800147885756 3.10693001602964e-08 79.9528095270684 16.8163862019789 4.75445845300936 4.62600446922989e-06 -43.027844318208 41.6937819349764 -1.0319966748354 0.303734735617544 DIXDC1 other 0.00032072838555474 1 0.0483787547392062 4.75445845300936 -1.0319966748354 1.08735781275604e-10 231.684689617411 45.8597030806834 5.05203204673603 1.25379807395342e-06 -224.190799930037 113.702458832907 -1.97173220554095 0.0504796378699064 DLAT other 1.28580061358401e-06 1 0.0136137394869863 5.05203204673603 -1.97173220554095 0.00388432552426379 8.24464566812751 8.25989376652756 0.998153959502258 0.319801554347221 -45.9590351117057 20.3761217853712 -2.25553398216836 0.0255367618546613 PIH1D2 other 1 1 1 0.998153959502258 -2.25553398216836 0.00311924987808985 94.7163704666956 82.5531500072365 1.14733805382827 0.253056551571191 -446.111296351868 203.82212404272 -2.18872852222051 0.0301527552078467 TIMM8B other 1 1 1 1.14733805382827 -2.18872852222051 0.0224920649095742 -9.45484756538062 33.272832787341 -0.284161184165174 0.776676149935123 -206.674909880371 82.149977935907 -2.51582428958919 0.0129210504436729 IL18 other 1 1 1 -0.284161184165174 -2.51582428958919 0.029033535659655 50.4388961127176 56.637934817277 0.890549704459414 0.374587512864694 -231.534884623595 137.246535225464 -1.68699985207815 0.0936681489150242 PTS other 1 1 1 0.890549704459414 -1.68699985207815 0.000310661975948182 141.32061191477 34.422288989348 4.1054972247343 6.56467325119958e-05 147.076767714259 141.073931427655 1.04255099596258 0.298811621290386 PIP4K2A other 1 1 0.612615307801945 4.1054972247343 1.04255099596258 0.27243545164847 -14.0238997885313 13.040230707903 -1.07543341085462 0.283873695446408 -61.1957276521872 40.4708636098449 -1.5120934468347 0.132572858872466 C2orf50 other 1 1 1 -1.07543341085462 -1.5120934468347 0.0130685855757777 38.1487997077688 18.7495127687568 2.03465552296047 0.0436469586740532 -24.0704663788471 32.2226701631406 -0.747004089263256 0.456230411877855 FREM2 other 1 1 1 2.03465552296047 -0.747004089263256 0.000188880318585456 193.587164554812 78.2266566832179 2.47469561863997 0.0144121067639013 -205.99161418247 137.272685172341 -1.5006016231405 0.135492884300976 FOXO1 og 1 1 1 2.47469561863997 -1.5006016231405 0.0467722580158717 162.691598360656 77.5119554918362 2.0989226413955 0.037465924547935 -316.038619167717 308.354529895834 -1.02491965749451 0.3070188172051 CRIM1 other 1 1 1 2.0989226413955 -1.02491965749451 8.44537646532158e-07 294.775887773752 94.7176739612854 3.1121529430108 0.00221430461648011 -206.999814078795 141.450649768096 -1.46340659741164 0.145394236016343 SEC24D other 0.00775201105751868 1 1 3.1121529430108 -1.46340659741164 2.72684291773744e-08 138.309959349594 54.9791780369465 2.5156789222394 0.0129935755587935 -458.255726545361 122.1742729406 -3.75083653469467 0.000255965065920814 ABCB9 other 0.000282746342140195 1 1 2.5156789222394 -3.75083653469467 6.60925411763351e-10 51.1041043267287 15.8353363324103 3.22721938163911 0.00153115865913852 -150.382989621243 37.5177818771639 -4.00831238140912 9.55244046294643e-05 RILPL2 other 7.52794043998457e-06 1 1 3.22721938163911 -4.00831238140912 5.88159015942399e-24 288.875209319257 29.7034517772887 9.7253077347775 1.23060350929134e-17 -143.912115928701 68.0117598221007 -2.11598870996919 0.0359971569810885 DHX37 essential 8.44478715090096e-20 1 1.74524189687698e-13 9.7253077347775 -2.11598870996919 0.606460351446386 1273.01317733991 1483.42425664129 0.858158528580499 0.392183265434079 -103.908011407822 3402.01432692489 -0.0305430846029814 0.975674806302111 UBC other 1 1 1 0.858158528580499 -0.0305430846029814 5.06749656041289e-07 341.017598720997 65.0881956291424 5.23931559977537 5.37125506366845e-07 74.8057555148741 124.576584202063 0.600480066089624 0.549092524295592 ITPR1 other 0.00473912278329814 1 0.00597337275630569 5.23931559977537 0.600480066089624 0.0546620622631783 -0.0241404535480745 6.41862759601787 -0.00376099924585924 0.997004161081251 -29.0732991953184 13.2986202457612 -2.18618914278609 0.0303519969810699 PRSS53 other 1 1 1 -0.00376099924585924 -2.18618914278609 0.0581248184984148 18.1736994083677 73.2759765424308 0.248017157408256 0.80444522151789 -189.168185934908 114.50725113939 -1.65201927434826 0.100529229602594 SLC7A11 other 1 1 1 0.248017157408256 -1.65201927434826 0.00334785647545248 19.7717404213877 10.4247373180171 1.89661761426029 0.0597268333390536 -15.4894593695812 16.1797022955749 -0.957338960051049 0.339877480057793 NOCT other 1 1 1 1.89661761426029 -0.957338960051049 0.596463761983439 -17.2933935375783 21.0360081867429 -0.822085320753809 0.412283059759186 23.5412048340467 87.489405326651 0.269074921085052 0.788227573552429 ENKUR other 1 1 1 -0.822085320753809 0.269074921085052 0.0485759782963357 20.2157241726437 9.86637066333638 2.04895243270818 0.0421315334942101 -23.9216081540204 41.1937175646654 -0.5807101074689 0.562268478015289 GPR158 other 1 1 1 2.04895243270818 -0.5807101074689 0.961312571387267 0.828942217066627 2.9562003202241 0.280407999212918 0.779569753520867 1.07859058942942 12.3588646661362 0.087272627265254 0.930576900786975 CACNA2D4 other 1 1 1 0.280407999212918 0.087272627265254 1.66779264829662e-19 149.742213441601 16.4994716125426 9.07557629468387 8.16624584365862e-16 -155.900402378018 68.9786599802247 -2.26012512308462 0.0253242025789575 DCP1B other 2.35025339997959e-15 1 1.14613260415749e-11 9.07557629468387 -2.26012512308462 0.0543920233291553 35.1409987280527 15.0824008673661 2.32993400965011 0.0211798051211495 13.3139846545726 67.357539414872 0.197661386835532 0.843584933788323 CACNA1C other 1 1 1 2.32993400965011 0.197661386835532 0.0580164774172811 3.96889690056799 1.93553666174472 2.05054080297831 0.0419959869836444 -4.25023115593507 8.78263963525364 -0.483935506003751 0.629114663266202 KCNA6 other 1 1 1 2.05054080297831 -0.483935506003751 0.00261584730496191 125.546699313326 42.8061040593258 2.93291580890726 0.00386762432627118 -42.3156717642876 94.0605791485267 -0.449876793735969 0.653427804453533 THRB other 1 1 1 2.93291580890726 -0.449876793735969 1.22223108370655e-07 98.1335297734606 28.0915917971133 3.4933417259589 0.000622919407194764 -172.303012926359 61.7046679263243 -2.7923821441206 0.00589584716556076 NGLY1 other 0.00120707541826859 1 1 3.4933417259589 -2.7923821441206 4.18264118442334e-07 33.7288089924902 12.3752404598616 2.72550736301954 0.00716405850371769 -89.478907442847 27.1828705400256 -3.29173871873073 0.00123476721346106 OXSM other 0.00394590369338497 1 1 2.72550736301954 -3.29173871873073 3.18909918218161e-56 138.006578628432 5.74280028225107 24.0312342142492 2.62038929887073e-54 -101.183611198962 33.3017234641977 -3.03838962892546 0.00278930488161271 UEVLD other 4.65576589606694e-52 1 3.82445818170182e-50 24.0312342142492 -3.03838962892546 0.751846527690542 -2.45144407830978 15.3459736611852 -0.159745098775339 0.873289851973868 -17.1767784454352 24.5038978100444 -0.70098147562443 0.484365587013999 TMEM86A other 1 1 1 -0.159745098775339 -0.70098147562443 9.44575170169347e-12 66.3834989341142 18.8885392516342 3.51448558566384 0.000578784938461364 -142.149751293292 37.998453053961 -3.7409352189003 0.000258189156675669 C12orf45 essential 1.16258311944443e-07 1 1 3.51448558566384 -3.7409352189003 4.26620619712198e-09 186.413361509534 66.2963815593789 2.81181803780002 0.00555918881937164 -465.266531332157 134.356824206593 -3.46291700536731 0.000689818041932081 TMEM263 other 4.64803165176439e-05 1 1 2.81181803780002 -3.46291700536731 0.754940031371922 7.61633860661164 15.3797014041597 0.495220187080594 0.62114601704146 -6.16926277677957 31.2111226074539 -0.197662315911258 0.843568257798109 BTBD11 other 1 1 1 0.495220187080594 -0.197662315911258 3.98241387767291e-12 279.729071920807 55.289893940037 5.05931648601422 1.18375904041674e-06 -278.705978746385 110.136540611287 -2.53054959961056 0.0123923497838727 UBE3B other 4.96248593296821e-08 1 0.0128792983597341 5.05931648601422 -2.53054959961056 0.000991854148619756 269.683803013393 76.6133797603687 3.52006142865528 0.000568614718290704 -16.4703892299107 180.393481454289 -0.0913025742234716 0.927371600824754 ANK3 other 1 1 1 3.52006142865528 -0.0913025742234716 0.217614187122746 11.0180759453581 17.8176906008735 0.618378452750661 0.537245379540664 -50.764432169026 38.4537552022278 -1.32014238666826 0.188759097933752 IPMK other 1 1 1 0.618378452750661 -1.32014238666826 0.00330610535248713 2.88357383096451 1.97098505125137 1.46301151758292 0.145515485217423 -7.39121912408232 3.89517307241263 -1.89753291745372 0.0596414287700854 RAD9B other 1 1 1 1.46301151758292 -1.89753291745372 0.00343167905699649 124.844757702638 84.4943425660003 1.4775516787425 0.141556853880278 -328.543102463604 169.747653588289 -1.93547949275612 0.0547517016993694 PLBD2 other 1 1 1 1.4775516787425 -1.93547949275612 0.0173565965345328 365.202240396244 153.865513472335 2.37351588510383 0.0188862625323723 -197.107945055576 374.491219194838 -0.526335291597387 0.599432648261269 DLG5 other 1 1 1 2.37351588510383 -0.526335291597387 9.42096293045036e-06 85.6111812443642 18.6360248218248 4.59385421852971 8.95547023412319e-06 15.8315118725578 45.0976398751756 0.351049676133328 0.726027773548372 MAT1A other 0.0780432569158507 1 0.091301019036886 4.59385421852971 0.351049676133328 0.522477570390973 -6.64445687411533 5.93040371494099 -1.12040548898473 0.264487076295529 -1.39837792794849 21.5241794954152 -0.0649677693055084 0.948293680903929 SLC2A13 other 1 1 1 -1.12040548898473 -0.0649677693055084 2.34786222671587e-05 86.9686705104291 23.4692580308811 3.70564209554452 0.000299249109658543 -120.692462798881 72.4723197058699 -1.66535945432288 0.0980002150721604 GXYLT1 other 0.18658461115711 1 1 3.70564209554452 -1.66535945432288 1.76085364048419e-08 328.378605337695 84.7905845596273 3.87281921740697 0.000162293397697735 -764.930705708701 236.741916139159 -3.23107423553617 0.00152626934676359 TWF1 other 0.000185100934687698 1 1 3.87281921740697 -3.23107423553617 0.000357022523564972 102.171273031826 24.9444528345407 4.09595166145913 7.00828507234418e-05 139.878559463986 93.3529339463777 1.49838418087999 0.136237722568847 DIP2C other 1 1 0.651840594578732 4.09595166145913 1.49838418087999 1.33938139156695e-13 81.5555811808121 40.0928135702511 2.03416956602233 0.0436285404360548 -279.980857933579 60.1555478935798 -4.65428157065229 6.90173475505816e-06 EIF4E essential 1.74146368531535e-09 0.100337419869035 1 2.03416956602233 -4.65428157065229 1.56642660417706e-11 543.893451992164 78.7009698096495 6.91088627379884 1.28692257709917e-10 90.4318664271701 187.521022682976 0.482249217358711 0.630331869635241 MAGI1 other 1.91245024103977e-07 1 1.67119765862098e-06 6.91088627379884 0.482249217358711 0.0008987148624275 46.7703989904497 12.5485113237134 3.727167134325 0.000270901802785973 17.1548958511848 25.0428954937893 0.685020462407759 0.49435412905728 TEX30 other 1 1 1 3.727167134325 0.685020462407759 1.50878695291093e-15 192.726775705228 34.0234823566476 5.66452233445683 6.97939588256688e-08 -138.178144813011 50.8893281499499 -2.71526761771853 0.0073737259912613 CSNK1G3 other 2.04244489815552e-11 1 0.000817566433683884 5.66452233445683 -2.71526761771853 3.1797260307823e-07 67.3775024698918 15.2502978202795 4.41811060111199 1.86118324659645e-05 -10.6499724220695 22.1186644212486 -0.4814925629885 0.630845541633469 SRFBP1 essential 0.00302709918130475 1 0.184108246753321 4.41811060111199 -0.4814925629885 0.00920039530397519 92.599081866871 32.841873582986 2.81954321615935 0.00545927067724044 8.06661163237095 56.2964852855873 0.14328801507678 0.886255028364808 AKAP6 other 1 1 1 2.81954321615935 0.14328801507678 6.85934342339062e-05 377.82750995457 86.0567133471398 4.39044782515073 2.14095844897026e-05 148.283810023424 144.888763932493 1.02343208678703 0.307773508270983 NPAS3 other 0.513833415846191 1 0.210520444287245 4.39044782515073 1.02343208678703 2.68146467865616e-08 131.064731220181 35.7269742097623 3.66850913404157 0.000338291961499974 -158.064128566186 54.841449774364 -2.88220186039053 0.00452923617479244 MBIP other 0.000278148331117004 1 1 3.66850913404157 -2.88220186039053 3.58251755241162e-05 24.3715676751404 8.81281356831857 2.76546956158864 0.00640336242049523 -29.3344468399315 13.3504097949636 -2.19726939400751 0.0295454439529364 MIPOL1 other 0.277788411013997 1 1 2.76546956158864 -2.19726939400751 0.00433489287894507 231.529379552051 100.517420717905 2.30337565268236 0.0226223788718156 -164.408333137756 175.834363258401 -0.935018218800309 0.351271784159569 EXT2 ts 1 1 1 2.30337565268236 -0.935018218800309 0.0730750648074289 40.8385256927631 41.5762114187673 0.982257023888636 0.327620686716244 -191.281668011838 119.719539041878 -1.59774811649523 0.112291096403948 TMEM18 other 1 1 1 0.982257023888636 -1.59774811649523 0.907320388644871 21.3864863700344 55.9457777812593 0.382271678367808 0.702808233957377 -25.851722057852 208.059228070293 -0.124251744551883 0.901284549727974 KCTD14 other 1 1 1 0.382271678367808 -0.124251744551883 0.258649073032411 -12.3299198575245 12.3106419554319 -1.00156595425018 0.318187994602569 -69.2448797862869 45.7825909992966 -1.5124718430058 0.132546292572852 THRSP other 1 1 1 -1.00156595425018 -1.5124718430058 0.00745940874360984 882.646583172955 280.810997113067 3.14320518871118 0.00201933834796928 265.623100565881 1044.32044043483 0.254350188200167 0.799578082069188 NDUFC2 other 1 1 1 3.14320518871118 0.254350188200167 0.000119057107668991 69.3202954879367 19.9166111512425 3.48052662983342 0.000649096195590677 -77.0074260423308 67.467613522505 -1.14139839875385 0.255453232489512 ME3 other 0.865545172753566 1 1 3.48052662983342 -1.14139839875385 0.309159467540468 -14.4791165865384 43.6758914896612 -0.331512788696388 0.740710830407627 258.562243339343 180.701456441292 1.43088079327876 0.154503662981751 ADAMTS12 other 1 1 1 -0.331512788696388 1.43088079327876 3.63108940883989e-09 80.5602981029809 18.3926022278385 4.38003807754006 2.20765835741988e-05 -76.2249322493225 31.4961779118085 -2.42013276857775 0.0167024879743278 NUBPL other 3.97459046691614e-05 1 0.216681667780762 4.38003807754006 -2.42013276857775 0.0015438758996244 164.392857560075 54.0049458487226 3.04403337465736 0.00274592118187495 -312.015455426924 199.471555130594 -1.56421027159811 0.119820794093585 NEK7 other 1 1 1 3.04403337465736 -1.56421027159811 3.59349424276679e-07 88.3852320493594 25.8910533471619 3.4137364310459 0.000815403115477702 -52.7474619601291 37.9989601206488 -1.38812909070809 0.167064353937022 FER other 0.00340555449387009 1 1 3.4137364310459 -1.38812909070809 2.91525964137407e-11 185.428759182657 31.6520270205352 5.8583533706184 2.71087878486818e-08 -91.1092649724003 50.749248590851 -1.79528303378319 0.0745569151368443 VIPAS39 other 3.5257150102778e-07 1 0.000323787362064655 5.8583533706184 -1.79528303378319 2.62410351164517e-07 136.230140206254 32.821466186923 4.15064151706091 5.46935864506814e-05 -26.9812352055086 49.1978241146417 -0.548423343736432 0.584195405933716 ANKRD50 other 0.0025180897297747 1 0.514830729260264 4.15064151706091 -0.548423343736432 1.91550008326149e-08 191.544761190298 34.3102680152326 5.58272413101695 1.05208845592277e-07 -165.854880386763 169.735049184858 -0.977139849331479 0.330042388047737 UPF2 essential 0.000200801873728302 1 0.00122084344425278 5.58272413101695 -0.977139849331479 1.04024295390018e-24 427.914843061773 37.4594737588557 11.4234077557112 2.59873226290608e-22 -254.940375541531 190.009446249834 -1.34172474354944 0.181647594199147 CDC123 essential 1.49670156207159e-20 1 3.74035534600072e-18 11.4234077557112 -1.34172474354944 1.6248607757214e-12 62.9810880239988 12.7926363909372 4.92322974712365 2.14699504613188e-06 -32.0996942456419 18.8378729498598 -1.70399780968269 0.0903725297637568 SCLT1 other 2.05008684072769e-08 1 0.0229814349737957 4.92322974712365 -1.70399780968269 0.0612388536988488 330.004336065894 147.035892376203 2.24437945547031 0.0262238662435539 -42.2822771560492 734.780633091073 -0.0575440822088304 0.954185907696871 CCDC3 other 1 1 1 2.24437945547031 -0.0575440822088304 1.61513843621035e-07 42.7460847492712 21.4478397562408 1.99302518272653 0.0480025673135925 -93.1318001499927 31.5831442425149 -2.94878177533146 0.00368133826554312 C4orf33 other 0.00158008993214458 1 1 1.99302518272653 -2.94878177533146 0.0103857252929666 113.105515737218 36.8946265662574 3.06563655100554 0.00256311283371108 158.280371681329 184.132655402306 0.859599680108383 0.391337277426844 FRMD4A other 1 1 1 3.06563655100554 0.859599680108383 0.325918665926798 4.57297832408687 5.36056623374141 0.853077478140803 0.394994838636203 -16.4852022191515 19.8656507971324 -0.829834491076988 0.407968876885485 PTPRO other 1 1 1 0.853077478140803 -0.829834491076988 0.0386893503808265 5.55643982730268 27.9472968341528 0.198818506858684 0.842679438029926 -238.956221589406 103.517886826573 -2.3083568348892 0.0223736893845957 EPS8 other 1 1 1 0.198818506858684 -2.3083568348892 1.29727297067821e-15 167.459374379258 19.7908826725548 8.46144040919835 4.02621089117088e-14 -57.028271252019 53.6056294556447 -1.06384855156316 0.289310652352904 ACAD8 other 1.75819405716018e-11 1 5.55778151417229e-10 8.46144040919835 -1.06384855156316 4.21176771985118e-10 245.948533115839 40.7076267818367 6.04182932190924 1.33983034292084e-08 -155.856422066032 109.548467119887 -1.42271659443181 0.157074901103472 THYN1 other 4.8477446455487e-06 1 0.000162186463010567 6.04182932190924 -1.42271659443181 5.33404802003767e-12 408.385407920934 61.291552079378 6.66299667843357 5.89609864197359e-10 -283.876040492239 164.94195580791 -1.72106629330162 0.0874798903833791 VPS26B other 6.61635316405473e-08 1 7.49747903313362e-06 6.66299667843357 -1.72106629330162 6.74938530243488e-14 434.515615331138 54.6812456615966 7.94633717783618 5.72715572257366e-13 -84.7597385730764 145.373692057714 -0.583047299503313 0.560799456906653 NCAPD3 essential 8.84844413149213e-10 1 7.80783139658468e-09 7.94633717783618 -0.583047299503313 3.50780574954528e-08 81.3304110738252 16.7851045887143 4.84539197500794 3.07135980462278e-06 -42.047399328859 31.9382802906953 -1.31652045589658 0.189968147251222 VTI1A other 0.000360742743283236 1 0.0325164862515414 4.84539197500794 -1.31652045589658 2.19440700170625e-06 93.4934395057589 36.7954302396562 2.54089811959846 0.0120729500874131 -145.544361957633 67.4582887727031 -2.15754601258915 0.0325552091183003 QDPR other 0.0193963634880816 1 1 2.54089811959846 -2.15754601258915 1.59018653554657e-06 118.477203231254 26.4787632132191 4.47442360797674 1.48124301668865e-05 -24.1484961891288 48.4535995938851 -0.498383946528842 0.618924495914653 FAM160B1 other 0.0142512517315684 1 0.147828053065528 4.47442360797674 -0.498383946528842 0.000525270750319146 40.0614297032117 19.3126766670847 2.07435926121467 0.0397211479924969 -63.9283226372017 29.5788708418721 -2.16128340324284 0.0322288067663877 TEX9 other 1 1 1 2.07435926121467 -2.16128340324284 5.67340217854853e-18 114.2860994165 16.5586327053528 6.90190436916663 1.25752294443797e-10 -43.8412733584461 26.5772740296098 -1.64957750405863 0.101067657083315 MMAA other 7.90645327602523e-14 1 1.63339655253048e-06 6.90190436916663 -1.64957750405863 7.11354731805201e-12 332.613423654416 59.6717210519576 5.57405447322027 1.0872330993028e-07 -82.751959946398 95.775521471869 -0.864019936145206 0.3889206908883 ZNF827 other 8.78807635672146e-08 1 0.00126042933202174 5.57405447322027 -0.864019936145206 0.266747169300255 -43.2977941176472 61.7133128975871 -0.701595686322976 0.483990251433616 -157.636379551821 98.9045691303835 -1.59382302494046 0.113026033635258 EDNRA other 1 1 1 -0.701595686322976 -1.59382302494046 5.18013256939429e-05 13.0825376136911 16.4172879959119 0.796875684762846 0.426742165196256 -77.3158076672426 25.9851429890179 -2.97538511525292 0.00339552517920404 NR3C2 other 0.393793677925354 1 1 0.796875684762846 -2.97538511525292 7.40687934891895e-09 26.2752106501394 4.06169585254186 6.46902466458586 1.24211429893237e-09 29.9877548270752 18.2742746815293 1.64098194591467 0.102841961991591 AKR1C2 other 7.95350704486917e-05 1 1.56245557662702e-05 6.46902466458586 1.64098194591467 0.489024903795859 -4.65660546014869 20.6685738578252 -0.225298827687895 0.822061860587061 32.9327438101233 38.8896168357167 0.846826132261542 0.398477978882754 DPYSL4 other 1 1 1 -0.225298827687895 0.846826132261542 0.178102691569728 -1.29635616670432 1.80824206046618 -0.716915171395861 0.474612323013593 3.90494879903622 3.44985401901769 1.13191711229222 0.259590635543981 VENTX other 1 1 1 -0.716915171395861 1.13191711229222 0.289792572584196 22.9185255251865 70.7859140136457 0.323772403656021 0.746590096262916 202.630920111438 135.048882718091 1.50042648286415 0.135739874809607 ADAM8 other 1 1 1 0.323772403656021 1.50042648286415 0.84537793066346 -0.0637568507825383 11.2627782439616 -0.00566084578791392 0.995490601864255 -22.5117807989308 42.1655957190565 -0.533889784195715 0.594182631015671 ITIH2 other 1 1 1 -0.00566084578791392 -0.533889784195715 7.41902686209798e-20 79.5429927287125 8.08450618615169 9.83894265118694 5.01311906846532e-18 -10.4405699654341 29.6491277855722 -0.352137507752072 0.725216555873094 KIN essential 1.04719564158513e-15 1 7.12514613200975e-14 9.83894265118694 -0.352137507752072 0.000115434210388877 133.134377437238 31.0292205038859 4.29061301815703 3.15749268906437e-05 -22.7815391749752 131.706346311518 -0.172972220496431 0.862903381705468 PIGF other 0.840594707367021 1 0.305455842740088 4.29061301815703 -0.172972220496431 4.97696905428044e-05 7.78218357953005 3.02993459911153 2.56843285720162 0.0111859001909733 -31.0571918529438 10.927808457413 -2.8420329633318 0.0051028239143953 ANKAR other 0.378946423792913 1 1 2.56843285720162 -2.8420329633318 0.118354923369289 22.2435213923994 13.8860191546834 1.60186451888173 0.111261753498135 -38.3686056699883 50.2626033491339 -0.763362880419713 0.446430201665626 INPP1 other 1 1 1 1.60186451888173 -0.763362880419713 0.225097061761035 32.761532869633 60.1518813217053 0.54464685309537 0.586794589409054 -293.985441245936 210.801878208361 -1.39460541691832 0.165169710007959 MFSD6 other 1 1 1 0.54464685309537 -1.39460541691832 1.01554609864952e-06 360.728494266768 69.5154171465659 5.18918693253627 6.57131671786223e-07 -6.48125374121625 211.318822918247 -0.0306704989726527 0.975572031118045 RNF144A other 0.00926178041968361 1 0.00726196210490955 5.18918693253627 -0.0306704989726527 1.75195164606846e-08 634.311064858332 108.771933222335 5.83156928508174 3.15464398024845e-08 -168.365713262611 338.10546242566 -0.49796803652538 0.619221574007374 ASAP2 other 0.000184217715584099 1 0.00037571809804759 5.83156928508174 -0.49796803652538 5.41891026058783e-09 391.570900414285 65.1529626634407 6.01002447788928 1.30505440399035e-08 -119.230015557537 205.176057843946 -0.581110763168195 0.562020866361276 ADAM17 other 5.86922170324268e-05 1 0.000158002936691111 6.01002447788928 -0.581110763168195 0.338556958023227 4.02020645929182 10.9037673520892 0.368698847790581 0.712858581622281 44.3722676188516 30.203260513864 1.46912177241539 0.143839588437118 FLI1 other 1 1 1 0.368698847790581 1.46912177241539 0.00402853327787223 68.9396121900229 32.5140315685273 2.12030341561071 0.0355724439189472 -156.949874229449 90.5111540043327 -1.73403903591745 0.0848994128642758 TMEM45B other 1 1 1 2.12030341561071 -1.73403903591745 0.00940661644712288 86.0411396362166 50.0285993277487 1.71983906790077 0.08744488113673 -63.5839866106211 78.8941444500134 -0.805940504886359 0.421503984969934 WWC2 other 1 1 1 1.71983906790077 -0.805940504886359 0.000149340874948954 116.336474665089 42.0031434954286 2.76970876424404 0.00629182148602926 -54.7005958669652 68.854483484255 -0.794437676371121 0.428147578554792 CENPU other 1 1 1 2.76970876424404 -0.794437676371121 0.677114465928444 74.5204149304197 88.9712732708303 0.837578379974153 0.403540763298141 45.4557437025387 145.140542340238 0.313184331335773 0.754556285055788 ACSL1 other 1 1 1 0.837578379974153 0.313184331335773 0.000352511213221595 132.088462840626 76.9258615343234 1.71708785844004 0.087947719869563 -223.8832545685 125.361724751522 -1.78589800844122 0.0760583393469888 SLC25A4 other 1 1 1 1.71708785844004 -1.78589800844122 1.94460560083652e-12 97.3894322274606 12.2020067784418 7.98142748121777 3.79148323701675e-13 -19.8565927791281 102.991000610346 -0.192799299564563 0.847382264165432 AMN1 other 2.44709168809268e-08 1 5.17840780511748e-09 7.98142748121777 -0.192799299564563 2.60810361148536e-26 616.983853042103 46.5417063610741 13.2565799856046 1.01527696251299e-26 -360.758794759629 392.982510657813 -0.918002162884439 0.360152761116406 BICD1 other 3.76557999426257e-22 1 1.46961340323755e-22 13.2565799856046 -0.918002162884439 1.14437744359888e-08 361.886707312785 59.2295624756286 6.10990005981713 7.556242078901e-09 80.5843574380899 96.1563221475517 0.838055737140542 0.403273438514797 SAV1 other 0.000121555772059073 1 9.24430655932748e-05 6.10990005981713 0.838055737140542 4.0440055861591e-10 36.4971540087819 6.42999716620333 5.67607621984879 6.72065477584535e-08 -3.84975334742782 10.9564108651413 -0.35136993261873 0.725794237648128 CCDC122 other 4.65829003469667e-06 1 0.00078786235937235 5.67607621984879 -0.35136993261873 0.00139881429627415 12.0277280858676 5.03509048491629 2.38878092099821 0.0181230528658774 -8.81240310077514 8.57955589558685 -1.02713977366918 0.305975776921915 SERP2 other 1 1 1 2.38878092099821 -1.02713977366918 1.02512414138305e-12 405.382777629629 52.8089655993859 7.67640064577108 1.71456493261633e-12 -4.0207826045141 165.392660976802 -0.0243105261186774 0.980636186248227 NBAS essential 1.30108756024337e-08 1 2.32032072330968e-08 7.67640064577108 -0.0243105261186774 0.315922705178361 3.26682015485706 53.2343666869028 0.0613667515586466 0.951145181888649 -93.585159549507 83.9156389475504 -1.1152290648469 0.266456424795097 TDO2 other 1 1 1 0.0613667515586466 -1.1152290648469 1.34201494641195e-10 195.605687011022 40.2659018520577 4.85784939648696 2.92432226468203e-06 -93.6667601354578 66.0679140646425 -1.41773448521187 0.158315027334171 GUF1 other 1.57995419641079e-06 1 0.0310036646501589 4.85784939648696 -1.41773448521187 1.12034345749856e-06 174.225447711753 34.3433961836745 5.07304073190564 1.12677692827133e-06 70.3528925002001 56.1246446161316 1.25351158980843 0.211944222863386 SACS other 0.0101794406548319 1 0.0122784881873727 5.07304073190564 1.25351158980843 0.015263026574534 5.80043438731186 6.54903853463953 0.885692511447579 0.377137789259651 -18.336511263764 9.20911064179503 -1.99112726266364 0.048201853553358 CCDC175 other 1 1 1 0.885692511447579 -1.99112726266364 0.495638429451141 -28.9331633466135 72.2786776055583 -0.400300120382786 0.689486647677773 86.1515697211153 118.977107969808 0.72410206628133 0.470094574465576 PABPC3 other 1 1 1 -0.400300120382786 0.72410206628133 6.1403769416903e-12 97.5953619980181 16.3180819556667 5.98081087367789 1.46169640513555e-08 -25.9661656148746 26.8952995090663 -0.965453669929254 0.335811914292273 CENPJ other 7.6036287668951e-08 1 0.000176602159668477 5.98081087367789 -0.965453669929254 0.00658024492382252 32.66802996265 12.47258954858 2.61918584231527 0.00973807162048792 -81.183597034056 54.3648859496648 -1.4933094333946 0.137499478258383 FBXO4 other 1 1 1 2.61918584231527 -1.4933094333946 9.90193100893606e-05 74.5199206011629 53.2827665246906 1.39857453847918 0.164321703751708 -213.191648327261 80.0229697573966 -2.66413067365018 0.00869607677984169 PARP8 other 0.726603697435728 1 1 1.39857453847918 -2.66413067365018 0.776557990991978 2.19352475441902 89.8152002862541 0.0244226450247613 0.980547102970742 -98.1139787829526 161.904608948323 -0.605998676753354 0.545407793937412 GFRA1 other 1 1 1 0.0244226450247613 -0.605998676753354 1.47444508024322e-06 369.127545240926 80.3342499094139 4.5948962697375 8.87826436601408e-06 -38.1425849817916 143.975608348389 -0.264923936903917 0.791417781939578 CACUL1 other 0.0132493634910656 1 0.0905671747977096 4.5948962697375 -0.264923936903917 0.438898284706933 17.4032588037334 64.2923636437821 0.270689360561665 0.78702580164171 -200.115183943249 195.826765745914 -1.02189904010823 0.308578793020935 DST other 1 1 1 0.270689360561665 -1.02189904010823 0.558577712417964 2.31728832937081 5.74435909215029 0.403402414820724 0.68728111526555 -12.6870964389186 17.2146560234291 -0.736993897621392 0.462386323548353 BEND6 other 1 1 1 0.403402414820724 -0.736993897621392 5.35666112305846e-07 299.678254405527 69.5868012075559 4.30653872868333 2.95127599651492e-05 -136.556561283833 124.41381575165 -1.09759965530213 0.274103733299141 TIAL1 other 0.00499990749226277 1 0.286155720622087 4.30653872868333 -1.09759965530213 0.0760442344945939 12.9874381137008 67.404850805593 0.192678093022693 0.847466600150967 -229.266391670432 120.512719989548 -1.90242483689951 0.0589944836322921 BAG3 other 1 1 1 0.192678093022693 -1.90242483689951 0.0572124242225301 2.8806937967163 5.06338210482724 0.56892680368127 0.570262383794161 -16.2637353861879 9.78962110665595 -1.6613242952917 0.0987510143188347 GLT1D1 other 1 1 1 0.56892680368127 -1.6613242952917 0.0394158565901519 21.6924004051508 10.3823274694467 2.08935813949114 0.0383415736720267 61.1025429435298 42.3326591561054 1.44339014277862 0.150968388774618 SCHIP1 other 1 1 1 2.08935813949114 1.44339014277862 0.382242454969364 13.384341598157 16.6114158135597 0.805731537177675 0.421648144614564 53.1104751454804 38.7700111746268 1.3698854742719 0.172729645282654 KCNE4 other 1 1 1 0.805731537177675 1.3698854742719 0.325078286324555 8.06766892666465 9.99450283757447 0.807210629460641 0.420798235882483 -18.7114244538338 23.3265479021541 -0.802151459886867 0.423709514695039 AP1S3 other 1 1 1 0.807210629460641 -0.802151459886867 0.156568272880693 4.6374322841058 26.2417352916254 0.176719726518458 0.859965350594209 -107.266586916606 63.9149570006588 -1.67827050115204 0.0953627358185822 CCDC74B other 1 1 1 0.176719726518458 -1.67827050115204 0.398648751811375 24.2784374719588 26.5781433772562 0.913473794137732 0.362412122205463 -61.5109622229535 81.9204832415284 -0.750861808781072 0.453874238135919 TMEM56 other 1 1 1 0.913473794137732 -0.750861808781072 0.330137572092014 -109.664766490812 153.011544787825 -0.716709099583824 0.474660688203242 -555.586686460868 372.678338419153 -1.49079414923225 0.138101562148606 MZT2B other 1 1 1 -0.716709099583824 -1.49079414923225 5.98250669308652e-13 743.778839711506 103.46963686705 7.18837779113114 2.76317555117277e-11 -201.70633153352 252.424163179003 -0.799076954413761 0.425492663126396 FAM168B other 7.6474383057725e-09 1 3.65208912598505e-07 7.18837779113114 -0.799076954413761 7.60302789410237e-08 462.964302602141 90.5549926889522 5.11252100911078 9.19696001450016e-07 -270.760845784136 269.253793544841 -1.00559714394161 0.316166638489473 PTPN14 other 0.00076425636391517 1 0.0100715909118791 5.11252100911078 -1.00559714394161 0.00501119218100553 399.618507562589 154.585205807948 2.58510188911003 0.0106626785797906 -371.432719401472 384.575275169304 -0.965825791161311 0.335645621279014 MGAT5 other 1 1 1 2.58510188911003 -0.965825791161311 0.987542342178117 1.9174260636216 14.0810109589729 0.136171051155936 0.891863902821878 4.35120478559847 35.0734280873599 0.124059865912183 0.901429654134259 TMEM163 other 1 1 1 0.136171051155936 0.124059865912183 1.5876698129281e-08 55.3534073364445 8.75657430799101 6.32135414941097 2.73612824633e-09 7.11266578191054 34.8920349088561 0.203847835200499 0.83874507590148 GPATCH11 other 0.000167276891490105 1 3.40237547431135e-05 6.32135414941097 0.203847835200499 0.148921625523685 -24.2428960042121 52.9193316831065 -0.458110396204251 0.647518891063775 -197.380949677126 105.706518368001 -1.8672542878574 0.0637667976889491 HSPB8 other 1 1 1 -0.458110396204251 -1.8672542878574 6.42778094967026e-06 74.8827107204519 15.7397267267835 4.75756104412078 4.49604720721277e-06 -66.1799651063112 61.5492843631996 -1.07523533037015 0.28396206127308 GEMIN6 essential 0.0540254988819785 1 0.0470556300706889 4.75756104412078 -1.07523533037015 0.12611426416588 62.9396347649643 31.179726666172 2.01860764973446 0.0452981450070631 12.2117010483598 128.545287115425 0.0949992125140652 0.924441403073421 TMEM178A other 1 1 1 2.01860764973446 0.0949992125140652 2.27238241313269e-14 127.797415782187 15.3028306820279 8.35122719695751 5.11849563405248e-14 31.2794703483609 28.2491529851694 1.10727108755375 0.270022922597133 RNF219 other 3.01272460333132e-10 1 7.05789362979497e-10 8.35122719695751 1.10727108755375 0.593611034035824 4.533067024419 6.29626552689326 0.719961222260544 0.472676717012519 10.7259885816043 10.6761595023604 1.00466732247985 0.31668584554975 CYSLTR2 other 1 1 1 0.719961222260544 1.00466732247985 0.000917542556846347 61.4923851214973 19.2576399174167 3.19314232612084 0.0017046238885283 15.8582793782274 29.0444241384948 0.546000819386508 0.585850365779315 GRID2 other 1 1 1 3.19314232612084 0.546000819386508 0.516451187223213 3.21396361374592 7.2445330065698 0.44363986068271 0.657950874662831 13.8965244937969 12.301108806118 1.12969690072861 0.260431577379696 ARL11 other 1 1 1 0.44363986068271 1.12969690072861 6.06576507438763e-06 157.965849947867 43.2182239233175 3.65507500327055 0.000356433250853417 -11.5864003095211 86.5280604296857 -0.13390338639263 0.893660883807797 SETBP1 other 0.0511465311072365 1 1 3.65507500327055 -0.13390338639263 4.55231698681502e-07 76.9447705499579 32.2793027232325 2.38371848393671 0.0183489505302545 -172.290765352725 52.7167662900342 -3.26823470932995 0.00133295812459239 ARL14EP other 0.0042796331993048 1 1 2.38371848393671 -3.26823470932995 1.64403676882219e-12 235.706957220061 47.9089536290002 4.91989366007324 2.2401554684993e-06 -138.823192802635 98.1095310049827 -1.41498171870361 0.159132790652939 EPG5 other 2.07362357651543e-08 1 0.0239383013363835 4.91989366007324 -1.41498171870361 0.396520250234116 6.89388181495602 31.1862368312218 0.221055263969979 0.825350024455441 -53.969365711358 64.0427997717993 -0.842707781415937 0.400733595839217 PSTPIP2 other 1 1 1 0.221055263969979 -0.842707781415937 3.41974475956584e-10 2006.00044802868 541.30169392665 3.70588245064776 0.000296346877200464 -2215.19380440348 1112.73828818301 -1.9907590382467 0.0483362137454318 ATP5A1 essential 3.95459283996194e-06 1 1 3.70588245064776 -1.9907590382467 2.87776416262529e-05 54.6041293923994 22.8526641485284 2.38939884809517 0.0181183634765463 -64.6640664137983 47.2237259985019 -1.36931309519816 0.172948120923045 HAUS1 essential 0.2262498184656 1 1 2.38939884809517 -1.36931309519816 3.81935398833721e-09 187.590758367327 59.6435077746646 3.14519996167985 0.0020016193816305 -265.151303704765 123.249904275238 -2.15133070702138 0.0330511523875719 C18orf25 other 4.17455390925257e-05 1 1 3.14519996167985 -2.15133070702138 0.408245301588422 13.7167553420459 22.9115262341829 0.598683614607096 0.550246682982629 -68.0864226228397 70.0296028477972 -0.972252017062259 0.33242072416711 SPC25 essential 1 1 1 0.598683614607096 -0.972252017062259 0.00694475827601277 135.700969690097 67.8797055007422 1.99913904589072 0.0473525819153658 -415.574385437635 219.842255681789 -1.89032988289184 0.0605925266513897 PDK1 other 1 1 1 1.99913904589072 -1.89032988289184 0.694880217534556 -0.361742624510986 14.8016942267039 -0.0244392715435481 0.980534069042359 -16.6650935258205 23.5167435924577 -0.70864800903665 0.479621259766499 PDE3B other 1 1 1 -0.0244392715435481 -0.70864800903665 0.77284151435934 4.65610122375945 10.2548073919214 0.454040826493483 0.650434569991441 12.2642425791609 17.664383679826 0.694292130507079 0.488538339810384 KCNK13 other 1 1 1 0.454040826493483 0.694292130507079 3.6874069842447e-09 2233.93820025184 620.470152942225 3.6003959089066 0.000427173491668611 -1294.70543411579 872.238588038306 -1.48434780560171 0.139747435418935 ATG10 other 4.03476072216055e-05 1 1 3.6003959089066 -1.48434780560171 3.51059259272962e-16 41.4282323520377 16.749393090708 2.47341692488073 0.0144760749126814 -112.421796165489 23.7209599508714 -4.73934429290917 4.86298814970459e-06 POC5 other 4.79582054092793e-12 0.0707564775782018 1 2.47341692488073 -4.73934429290917 0.759466408714514 -18.56044486042 51.5193263063495 -0.360261792828074 0.719144994144311 32.7592185813747 85.0552892347859 0.385152044935694 0.700656205665301 SPOCK1 other 1 1 1 -0.360261792828074 0.385152044935694 4.89911711073392e-05 0.0940557295534361 2.51336201781267 0.0374222769687953 0.970196464253151 -11.5486261341255 3.53320998157693 -3.26859320401081 0.00133138047391582 FAM151B other 0.373361715009032 1 1 0.0374222769687953 -3.26859320401081 0.0547216363259908 119.64190695105 60.3876724442704 1.9812306404335 0.0493459352458583 -48.1478439490244 163.477258464188 -0.294523191796563 0.768754778701724 GUCY1A2 other 1 1 1 1.9812306404335 -0.294523191796563 2.52444139178694e-20 117.064624381695 13.2887264719333 8.80931853243752 2.47274894403006e-15 -60.8159689371188 35.9743054199841 -1.69053907301668 0.0929479057301219 CWF19L2 essential 3.57183212523934e-16 1 3.45764484843723e-11 8.80931853243752 -1.69053907301668 8.78244481527644e-12 283.573219408756 46.2942680919798 6.12544989036955 7.06388702750897e-09 50.0329300236994 64.9937540320332 0.769811357550448 0.442575916268297 JMY other 1.08217285013836e-07 1 8.657499940915e-05 6.12544989036955 0.769811357550448 0.00021781269637781 38.8652920610017 26.7279275613645 1.45410795400321 0.147925334673818 -69.0667489170153 37.6300357687588 -1.83541544689032 0.068348407722578 HOMER1 other 1 1 1 1.45410795400321 -1.83541544689032 2.68320113456926e-11 36.1519844357976 10.4455653050284 3.460988790946 0.000696613278944244 -35.6221167315175 15.1832877211012 -2.3461398733827 0.0202431259734992 XRCC4 other 3.24881993373646e-07 1 1 3.460988790946 -2.3461398733827 1.58409776908701e-06 16.1618004137712 5.27115252804637 3.06608475618541 0.0025594958194158 -21.0797347912131 10.6135224840123 -1.98612051964526 0.0487832376684768 ZNF547 other 0.014201436499865 1 1 3.06608475618541 -1.98612051964526 1.19939380971446e-08 40.505808019441 7.75893329794329 5.22053824462934 5.69278577670989e-07 -2.79154313487234 15.6609617729022 -0.178248512150926 0.858762076986117 ZNF773 other 0.000127291665024996 1 0.00631728437641496 5.22053824462934 -0.178248512150926 8.18891468365352e-10 113.965493568779 22.8214201793806 4.99379498177543 1.59647046649605e-06 -60.3599830916267 44.7899507627134 -1.34762334103468 0.179771703728134 ZNF776 other 9.28483327044416e-06 1 0.0172307057448918 4.99379498177543 -1.34762334103468 3.55006771600287e-06 30.5469469401263 9.92455093085918 3.07791729348119 0.00247090901065054 -35.0714716790126 19.4950384776421 -1.79899474008396 0.0739904988083176 ZNF256 other 0.0306583847954008 1 1 3.07791729348119 -1.79899474008396 3.93293183007566e-13 100.481120143639 13.1536037868558 7.63905632037114 2.06734330158655e-12 -47.0575521905395 64.9190523886604 -0.724865050537293 0.469620662560258 SUV39H2 other 5.05381740164722e-09 1 2.79298080044342e-08 7.63905632037114 -0.724865050537293 1.70639944865295e-08 61.9894232281143 11.4751081873 5.40207745463531 2.3988733215875e-07 -83.887409587641 56.6535085093379 -1.48070987649096 0.140687935788836 DCLRE1C other 0.000179496158003804 1 0.00272607964265203 5.40207745463531 -1.48070987649096 7.45243089226714e-22 171.929615732648 16.0166797952578 10.7344104977083 1.66837215832341e-20 -73.3886756965469 80.4620024903564 -0.912091091759029 0.363119155482881 RPP38 other 1.06279116954622e-17 1 2.3926125122516e-16 10.7344104977083 -0.912091091759029 3.36522598474682e-22 129.523036616969 11.6889657061353 11.0807953306754 1.91089688447433e-21 -16.3900188083023 58.7211332048491 -0.279116187201728 0.780522993769116 NMT2 other 4.80217748023371e-18 1 2.74481228485893e-17 11.0807953306754 -0.279116187201728 0.0997046940042679 13.5080032631934 7.4170237503084 1.82121612629753 0.0705799800368394 0.833084843029137 14.5984468050101 0.0570666766236546 0.95456853758426 ZSCAN1 other 1 1 1 1.82121612629753 0.0570666766236546 3.88030932479308e-10 55.9688832404069 10.9471925634131 5.11262434785902 1.03238737619481e-06 -14.9810242233988 19.3170225299942 -0.775534852751624 0.439341127217548 ZNF837 other 4.47593680614882e-06 1 0.0112757349227997 5.11262434785902 -0.775534852751624 5.80038535651837e-05 78.5555215801893 28.7996802866759 2.72765255718942 0.00711491121874706 -77.3106456485923 47.0389632582246 -1.64354484651774 0.102297173496035 USP12 other 0.438393125245659 1 1 2.72765255718942 -1.64354484651774 3.12418168372934e-13 312.783162904619 40.1510045059394 7.79017030217388 9.97973496437795e-13 -159.315868468621 148.035561166233 -1.07619998339265 0.283554295494548 CCDC50 other 4.02300875413828e-09 1 1.35534780551217e-08 7.79017030217388 -1.07619998339265 0.551039746763058 -4.88494203289307 7.64830100599897 -0.638696362638127 0.523951119818572 -12.6186977622002 11.5641114328577 -1.0911947567667 0.276858979353629 CAMK4 other 1 1 1 -0.638696362638127 -1.0911947567667 0.113136403805198 21.067878344132 12.6345325830949 1.66748379534997 0.0974772372555904 -0.0310640943504409 18.9260666171879 -0.00164133916353384 0.998692553573417 TRIM36 other 1 1 1 1.66748379534997 -0.00164133916353384 0.185657704582777 643.003151373238 530.990540223113 1.21095029509012 0.227793909071079 -2497.84809015074 2390.3511873214 -1.0449711755325 0.297695277347845 ZFP36L2 other 1 1 1 1.21095029509012 -1.0449711755325 1.34402100387691e-12 232.093535870552 42.2086951315686 5.49871383484123 1.54348574149644e-07 -145.808451892824 69.1184256549599 -2.10954532761932 0.0365041426835448 PAN3 other 1.70032097200469e-08 1 0.0017759346941658 5.49871383484123 -2.10954532761932 0.197528862605329 24.644921256876 15.0958284711801 1.63256500323426 0.10460355355959 -26.6239168110918 68.2672177946344 -0.389995632913934 0.69707863991536 PLEKHH2 other 1 1 1 1.63256500323426 -0.389995632913934 1.37554947719509e-09 453.331501831502 80.4010793628189 5.63837582062541 8.51833292165984e-08 -344.927326007326 231.805110297325 -1.48800570257017 0.138891423150815 PFKM other 1.5419909639357e-05 1 0.000992896885348671 5.63837582062541 -1.48800570257017 3.32431223601787e-07 1193.38306359285 269.279994145906 4.43175538300938 1.75966300988044e-05 -851.066389596605 761.346119394631 -1.11784426020758 0.265363107239823 TMEM123 other 0.00316042364278219 1 0.174382604279152 4.43175538300938 -1.11784426020758 0.0191547821405946 65.1195226422172 25.5521888170626 2.54849097697389 0.0118041199178153 -112.965384581832 106.928124338647 -1.0564609197115 0.292422957864723 IGSF10 other 1 1 1 2.54849097697389 -1.0564609197115 0.109310669964998 20.9612196771889 15.8141766257734 1.32547018875627 0.187017157721067 -93.832136331738 65.5503592501645 -1.43145113779834 0.154367456927216 SPEF2 other 1 1 1 1.32547018875627 -1.43145113779834 0.256459861735797 -300.236166286089 196.17572465224 -1.53044504776682 0.127944951874151 -435.680578059995 295.186899106318 -1.47594821917579 0.141986401764206 SPARCL1 other 1 1 1 -1.53044504776682 -1.47594821917579 5.25362894373161e-07 259.180506061748 46.5766176169921 5.56460557512002 1.15699599685635e-07 -94.6173224553319 189.838018084337 -0.498410821025837 0.618914948504022 MBNL1 other 0.00491056697370593 1 0.00134049556195777 5.56460557512002 -0.498410821025837 0.189673992407443 -45.0308252228158 26.6794801740943 -1.6878449253498 0.0935054021393193 -106.635553396956 110.683731479102 -0.96342571732947 0.336874260517117 CAPSL other 1 1 1 -1.6878449253498 -0.96342571732947 1.16882243182963e-11 132.018575870921 17.0786504064523 7.73003561341385 1.40057462511173e-12 83.7241057405435 70.8532828705081 1.18165457334642 0.239200412413991 NADK2 other 1.4337944771254e-07 1 1.89707832971384e-08 7.73003561341385 1.18165457334642 4.91331233897503e-07 199.158447809085 48.5675750347629 4.10064631941237 6.65049232807209e-05 -179.842564925299 107.056344931498 -1.6798870262232 0.0950068061105872 GPD1L other 0.00460279099915181 1 0.6198923898996 4.10064631941237 -1.6798870262232 0.354254550377202 115.431539657417 244.220487543618 0.472652973624095 0.637134313531833 -394.602585470386 501.589684030638 -0.786703949529957 0.432672040355807 GJA1 other 1 1 1 0.472652973624095 -0.786703949529957 0.134685787149643 -69.6096279194356 125.474195764143 -0.554772457360734 0.579876592902805 -375.884408842175 202.20804865136 -1.85889934327125 0.065000734364836 CCNO other 1 1 1 -0.554772457360734 -1.85889934327125 5.27379731237256e-24 332.060783312771 26.754753566775 12.4112816993066 5.90987123687743e-25 88.003091277775 165.884451211778 0.530508378783646 0.596523661665243 SLC30A6 other 7.57370032029823e-20 1 8.53562702742207e-21 12.4112816993066 0.530508378783646 1.91946004734154e-08 48.2738903583927 30.1224446792002 1.60258872984921 0.111216781904168 -178.979839071521 45.9178245376199 -3.89782923894586 0.000148258524387739 PELO essential 0.000201197802162341 1 1 1.60258872984921 -3.89782923894586 0.557123371816616 -0.624861519868386 6.80679391118991 -0.0917996824968 0.926976501046156 29.0277295972607 27.5605654581428 1.05323418132861 0.293883403389711 RASGRP3 other 1 1 1 -0.0917996824968 1.05323418132861 0.00231552196896873 62.4217917045897 56.46291273166 1.10553615966022 0.270618581918098 -221.153246218524 93.4599083315028 -2.36628999714072 0.0191874581882013 SAR1B other 1 1 1 1.10553615966022 -2.36628999714072 4.3493302808658e-08 2.37934724451577 1.45803738042208 1.63188356928612 0.104708209307306 -10.2589352594971 2.38066743272128 -4.30926853473623 2.87931217397573e-05 CATSPER3 other 0.000444458061401676 0.415887850409054 1 1.63188356928612 -4.30926853473623 3.1803039145211e-06 110.182739662096 23.1077845400835 4.76820871645959 4.38301127588912e-06 1.51545619414499 43.1494968230914 0.0351210629490815 0.972030212814677 GPR180 other 0.0275954970662996 1 0.0459076601036627 4.76820871645959 0.0351210629490815 0.0422190336202818 8.7200072788403 18.9107035894716 0.461114904455227 0.645354328808786 -133.187391142345 58.4261145958199 -2.27958665510634 0.0239789188490323 WDR78 other 1 1 1 0.461114904455227 -2.27958665510634 0.241137352784864 -16.568373927744 10.2626793112958 -1.6144296655073 0.10844225220807 -8.46140922087946 18.3667514854599 -0.460691659468359 0.645657333191928 ANKRD22 other 1 1 1 -1.6144296655073 -0.460691659468359 6.35947137450044e-13 1999.86515028433 272.720493760553 7.33302115549922 1.19687183961021e-11 -128.972161469724 520.529112812569 -0.247771274065441 0.804641434397338 FARP1 other 8.12168089237451e-09 1 1.59387422880892e-07 7.33302115549922 -0.247771274065441 0.118408049569298 42.7979421849542 62.7226813456987 0.682335979054714 0.496025648932671 -140.059774748556 112.464506692463 -1.24536868446462 0.214840005232814 IFIT5 other 1 1 1 0.682335979054714 -1.24536868446462 5.63854126684381e-10 113.59461376983 22.0838544797303 5.1437856500138 7.92955414262673e-07 -33.6044163367255 39.7421125975056 -0.84556190248514 0.399084007946728 PANK1 other 6.44598037625584e-06 1 0.00871378704733252 5.1437856500138 -0.84556190248514 0.829728077435958 -1.98321195860483 3.24572995191899 -0.611021861948892 0.542080118573939 -1.79916187555895 5.12889843642779 -0.350789140759831 0.726222849610282 PRDM8 other 1 1 1 -0.611021861948892 -0.350789140759831 0.381830725419232 35.1609746434233 32.7877745679686 1.07238063902553 0.285237658179387 70.0643291072373 51.7865249832336 1.35294517502229 0.178068985766522 BMP3 other 1 1 1 1.07238063902553 1.35294517502229 1.39287776141432e-06 468.386087517472 182.439649419872 2.56734810117682 0.0112129504556566 -626.03569508655 279.396143407246 -2.24067407463834 0.0264967359337537 HNRNPDL other 0.0125442571192974 1 1 2.56734810117682 -2.24067407463834 0.934795073262169 -8.25035542617291 26.9469893014756 -0.306169840863117 0.759883559077221 -0.547341261781759 47.7486405669542 -0.0114629705742987 0.990868719431346 HHEX other 1 1 1 -0.306169840863117 -0.0114629705742987 3.64088236671131e-09 612.221189702762 98.6893876014724 6.20351594616266 5.05209868506487e-09 338.061642600972 205.334990839381 1.64639081346546 0.101763051924088 UTRN other 3.98494575036553e-05 1 6.22340161768944e-05 6.20351594616266 1.64639081346546 4.9742021578853e-07 259.625875414669 82.0342647926621 3.16484673899208 0.00187245336213437 -279.089538026786 163.883278222594 -1.70297751578848 0.0906028281166011 PTPRK other 0.00465635063999643 1 1 3.16484673899208 -1.70297751578848 2.12257582645354e-12 194.513946221211 29.1253372706945 6.67851309028197 3.95289485807901e-10 -171.477977958669 95.0122362036546 -1.80479888496797 0.0730225715651901 GGPS1 essential 2.66765329868681e-08 1 5.04863731273851e-06 6.67851309028197 -1.80479888496797 3.81389286874218e-06 539.385907255784 141.647833278457 3.80793616655921 0.000202371219537854 1.80792740444378 205.839920073561 0.00878317191241466 0.993003574758699 PART1 other 0.0328528731713452 1 1 3.80793616655921 0.00878317191241466 2.06301855039682e-09 25.2597953581232 42.3736101366244 0.596120917634314 0.552043509664674 -257.940687130854 60.5542313002225 -4.25966413233795 3.70618583288199e-05 MARVELD2 other 2.29160100578079e-05 0.534283749668268 1 0.596120917634314 -4.25966413233795 2.07335837443357e-22 125.551824946846 28.6300025965652 4.38532356130168 2.24071835398016e-05 -184.652053065202 41.3123688233212 -4.46965541615141 1.58968684459545e-05 RAD17 essential 2.96179243787836e-18 0.230361520650327 0.219747248974834 4.38532356130168 -4.46965541615141 1.21160985510484e-33 177.274187071497 11.1817716692231 15.8538550343887 1.03405809946248e-33 -206.651268448609 138.471974802336 -1.49236889806472 0.137731062541451 MED21 essential 1.76083260242386e-29 1 1.50362388242839e-29 15.8538550343887 -1.49236889806472 0.525578281756186 108.306743504931 104.171195648651 1.03969953335496 0.300141433045299 226.169427282927 434.58792576756 0.520422712811156 0.603531206004713 PLOD2 other 1 1 1 1.03969953335496 0.520422712811156 0.195235131420951 -40.8684750675872 39.6214665886457 -1.03147305201718 0.303946786044729 -137.381573751427 75.6105138927642 -1.81696389401969 0.0711795804374867 STK32B other 1 1 1 -1.03147305201718 -1.81696389401969 0.0001031455371476 406.487135316666 102.5372704039 3.96428668049668 0.000112978139380107 926.726801089117 421.62558035705 2.19798523681681 0.0294626633823261 ZIC1 other 0.755231622994726 1 1 3.96428668049668 2.19798523681681 1.95555302203232e-16 720.081109184553 94.612084095544 7.61087884352468 2.94582303526706e-12 -9.16719725239356 175.27113208435 -0.052302949968862 0.958357831557229 ADGRA3 other 2.67988986139309e-12 1 3.96979112232589e-08 7.61087884352468 -0.052302949968862 0.542762804129588 -7.85554417401257 7.12865111627554 -1.10196782615402 0.272217483087944 -5.78159941136585 28.5211079671745 -0.202713001823772 0.839630450133509 CPB1 other 1 1 1 -1.10196782615402 -0.202713001823772 1.5627083860368e-09 33.0772634445204 48.5185957883254 0.68174403869453 0.49643150165679 -291.065743310467 67.1450278712467 -4.33488156217014 2.63216789280934e-05 SREK1IP1 other 1.74601407971892e-05 0.380506190584518 1 0.68174403869453 -4.33488156217014 0.681701522460916 11.359432726103 14.2416628911802 0.797619829432825 0.426327298650946 4.74211081519589 25.9160354887967 0.182979793234419 0.855056120227258 LGI2 other 1 1 1 0.797619829432825 0.182979793234419 2.09847359458425e-13 89.1090598597876 26.2270099212054 3.39760651814677 0.000867913088270845 -111.680352327881 36.1298822614895 -3.09107988560814 0.00237275572601022 CWC27 other 2.71542483139202e-09 1 1 3.39760651814677 -3.09107988560814 2.92490847421174e-08 109.679644502678 36.0228578761743 3.04472357189684 0.00273998944994844 -130.357391618742 53.7817190663051 -2.42382344562156 0.0165168432832693 SRP19 essential 0.000302640279826689 1 1 3.04472357189684 -2.42382344562156 1.35298894074106e-08 68.3709538844855 25.741862394583 2.6560220405371 0.00879827204140557 -75.8076766114655 37.0208138771308 -2.04770421479834 0.042406352648107 CENPH essential 0.000143146229930404 1 1 2.6560220405371 -2.04770421479834 8.18637109762253e-22 221.66925592066 22.1278374311901 10.0176646999498 1.98686938101563e-18 -55.2609374475803 57.2466750484078 -0.965312612494116 0.335931706585671 CDYL other 1.16721279109902e-17 1 2.8294101188467e-14 10.0176646999498 -0.965312612494116 4.20834299785535e-08 637.738612265672 130.802085664131 4.87559972020043 2.69119907365098e-06 -227.682415811348 298.360891188149 -0.763110791446756 0.446572345149709 CARHSP1 other 0.000430387238390667 1 0.0285993725556889 4.87559972020043 -0.763110791446756 0.161113146479012 3.0735525440135 23.7987265889268 0.129147773202436 0.897407081205346 -45.5483317200073 35.0848061450208 -1.29823523982821 0.196122547801132 BANK1 other 1 1 1 0.129147773202436 -1.29823523982821 3.73664610081254e-10 259.801410296601 48.556212497753 5.35052873633057 3.09872032566412e-07 -120.547704207851 107.213728125792 -1.12436817854533 0.262595099008813 TXNDC11 other 4.31171593572759e-06 1 0.00349690588751196 5.35052873633057 -1.12436817854533 0.000198482232322955 -50.5685137027406 54.8972713053966 -0.9211480370568 0.358462179773179 881.130889511234 223.760701904852 3.93782680341211 0.000125877101646174 DAB2 other 1 1 1 -0.9211480370568 3.93782680341211 1.36773357200564e-07 12.9725254644419 2.39370015936274 5.41944462580286 2.29696549140074e-07 -2.6357615339763 6.7526390993159 -0.39033057967563 0.69683858242424 ACOXL other 0.00134639692828235 1 0.0026125685499192 5.41944462580286 -0.39033057967563 8.41296038697263e-06 137.308572401037 55.2691423027744 2.48436228029079 0.0140628579197361 -506.415170139577 155.914503259559 -3.24803119371468 0.00143023569803578 BCL2L11 other 0.0700463081819341 1 1 2.48436228029079 -3.24803119371468 9.19650415334916e-15 317.480253878702 42.8510277512327 7.40892973960395 8.03200482926637e-12 -264.700705218618 120.944227127197 -2.18861793990574 0.0301407489920949 ANAPC1 essential 1.22782526951365e-10 1 1.07235296475535e-07 7.40892973960395 -2.18861793990574 7.48208466435875e-07 313.115102887915 231.303258525814 1.3536994890756 0.177790298609651 -1047.55261051804 336.551297008482 -3.1126090430477 0.00220629780573634 CAST other 0.00689324460127371 1 1 1.3536994890756 -3.1126090430477 2.0309054285686e-08 394.058421216251 102.199777336213 3.85576594672896 0.000169487722996487 -215.916499270632 161.3488171814 -1.33819697623121 0.182817608916072 SCOC other 0.000212513944045419 1 1 3.85576594672896 -1.33819697623121 0.00082923871654678 -164.230968753945 118.198615920661 -1.38944916972786 0.166701816351606 -679.49121544413 186.170616613358 -3.64983061132202 0.000358839470708797 CLGN other 1 1 1 -1.38944916972786 -3.64983061132202 4.5699974260339e-07 7.68464518760189 26.9554924621032 0.28508643269663 0.775963466553471 -156.656956420415 39.4905727934371 -3.96694566168586 0.000111548884941368 CETN3 other 0.00429488358098666 1 1 0.28508643269663 -3.96694566168586 2.45564274832176e-23 962.479401718248 93.9068171751298 10.2493027734428 3.82778335558347e-19 174.687910154229 151.49580845933 1.15308741496386 0.250649600340667 SMARCA5 other 3.51991831544441e-19 1 5.4660746317732e-15 10.2493027734428 1.15308741496386 4.54958918185243e-09 160.15775566095 24.4989967550124 6.53731894667003 8.57374026777096e-10 138.858305504775 67.1917485955764 2.06659758686376 0.0404357022964746 BMP6 other 4.95131790661e-05 1 1.08483535608106e-05 6.53731894667003 2.06659758686376 1.1277054556199e-06 14.8743046448172 3.34507604703031 4.44662675397838 1.65508695485272e-05 -14.0771712174232 9.15998288685765 -1.53681195601583 0.126378196285196 RGPD3 other 0.01024182094794 1 0.16451564331236 4.44662675397838 -1.53681195601583 3.64416625657376e-05 95.2803594648946 28.2829499657823 3.36882678716924 0.000961056840957213 -174.309181000482 86.5865058320773 -2.01312178295462 0.0459027626235863 RASSF3 other 0.282277118234204 1 1 3.36882678716924 -2.01312178295462 5.57867722262288e-09 1666.96912386052 315.484128330136 5.28384465070818 4.41095992669286e-07 -1307.94032934548 1005.91168879539 -1.30025363450323 0.195521718941903 HNRNPU essential 6.03557088715569e-05 1 0.00493277648602062 5.28384465070818 -1.30025363450323 3.26067407623855e-15 603.616166291583 74.3820147015896 8.11508223746302 1.48038799893244e-13 -239.145377449338 205.8162202301 -1.16193649451912 0.247070619980266 RANBP2 other 4.38560663254085e-11 1 2.03079625693552e-09 8.11508223746302 -1.16193649451912 5.41872349626466e-11 245.117119193989 40.8496025853145 6.00047745096324 1.36868507572539e-08 -221.466589822404 129.502786533504 -1.71012991882694 0.0892689083042968 AHCTF1 essential 6.48567015267917e-07 1 0.000165583520461257 6.00047745096324 -1.71012991882694 0.00391066237147926 74.0398396776031 25.3676949146548 2.918666434877 0.00404256727627475 -44.3244831135835 71.6155141071432 -0.618922920071064 0.536881597433998 MERTK other 1 1 1 2.918666434877 -0.618922920071064 0.00351054069019602 28.3205024509138 45.9619325487162 0.616173012762163 0.538684182218296 -383.05059250775 129.821935131847 -2.95058452270584 0.00366434098308125 TMEM87B other 1 1 1 0.616173012762163 -2.95058452270584 0.387328330169695 -14.1663442542751 16.3460395890187 -0.86665300038745 0.387480447820209 44.9270240091421 58.2422443792989 0.771382086798677 0.441662470674791 PTPRR other 1 1 1 -0.86665300038745 0.771382086798677 0.213075837454813 67.6830207212349 54.0373860363788 1.25252210896489 0.21226615771112 -138.172905667464 163.988172011696 -0.842578485828896 0.40076248719066 NR4A2 other 1 1 1 1.25252210896489 -0.842578485828896 5.27748092048332e-07 6.78771433110538 2.07145142282487 3.27679145951145 0.00129577319414699 -23.7798020947993 6.6881573927367 -3.55550874454959 0.000500537720800078 CCDC148 other 0.00492969492782347 1 1 3.27679145951145 -3.55550874454959 0.0195282686842344 5.69061300650956 15.3564917075989 0.370567256822966 0.71145935886428 -126.69367697886 48.4435535404188 -2.61528454705853 0.00978455286728838 PLA2R1 other 1 1 1 0.370567256822966 -2.61528454705853 0.0249791533620312 -3.49049631072497 3.0085014431379 -1.16021094777483 0.247843768264626 11.1368097468602 7.04535202131872 1.58073148270818 0.116088753671672 FEZF2 other 1 1 1 -1.16021094777483 1.58073148270818 1.62329147830202e-05 64.7286664118717 15.2695622747043 4.23906496122039 4.32403231481115e-05 -13.9576557104826 41.2588287827413 -0.338295005512157 0.735708422624092 SLC25A27 other 0.13114571853202 1 0.411518155400577 4.23906496122039 -0.338295005512157 0.0695184247535595 67.0273092990871 31.7810824431194 2.10903166747231 0.0366141900544472 0.155404308955725 88.3767201564782 0.0017584303726204 0.998599328357549 ADGRF1 other 1 1 1 2.10903166747231 0.0017584303726204 0.246024676222864 -5.43208089083504 3.72981981013191 -1.45639231044862 0.147388203952895 -14.1430185747581 10.1953279208072 -1.3872058539573 0.16745048875918 ADGRF4 other 1 1 1 -1.45639231044862 -1.3872058539573 0.654171892952403 4.59571578492499 9.50650109280861 0.483428733669584 0.629535941221776 -6.92651398234459 20.1444131462746 -0.343842927170382 0.731473026619212 FRMD1 other 1 1 1 0.483428733669584 -0.343842927170382 1.30272943889569e-06 311.771700854963 57.6839280741936 5.40482784830395 2.58213573502149e-07 151.999181172346 373.840983729646 0.406587794778191 0.684906148289619 FAM49B other 0.0117597386449114 1 0.00292736728279386 5.40482784830395 0.406587794778191 0.00123204087700399 185.471921515561 50.216739252218 3.6934282129314 0.000311993956889165 55.4888362652231 325.447240305795 0.170500251325176 0.864852785609821 ASAP1 other 1 1 1 3.6934282129314 0.170500251325176 9.70278118641155e-24 279.88671402454 28.2849561601192 9.89525005589969 4.41193297516727e-18 -50.4502492200509 75.3926580035571 -0.669166607943051 0.504417832676902 TRAPPC8 essential 1.39234910025006e-19 1 6.2720039174978e-14 9.89525005589969 -0.669166607943051 0.0447063965740447 -18.7147389796092 34.6499280475582 -0.540109028622588 0.589902046921694 -110.236906675692 50.1033596503376 -2.20018991630532 0.0292829738275861 FAM81B other 1 1 1 -0.540109028622588 -2.20018991630532 6.27766480757944e-20 128.027995429221 13.8942521699253 9.21445745071068 2.62417135847795e-16 17.306426917862 35.6884082800688 0.484931319493095 0.62843249444227 INO80C other 8.8665737742252e-16 1 3.69404602132941e-12 9.21445745071068 0.484931319493095 0.0122052753275093 268.72733162107 91.8711470426732 2.9250460048817 0.00406022086198045 61.1182149654869 331.751767917563 0.184228754375995 0.85411888349262 LPCAT1 other 1 1 1 2.9250460048817 0.184228754375995 0.000969873544121693 328.762373726234 87.7060457684814 3.74845737081879 0.000276056212418244 138.435341214874 299.745751115062 0.461842547225077 0.645037430458758 PLEKHG4B other 1 1 1 3.74845737081879 0.461842547225077 1.22842225049825e-29 562.647907185705 39.4665840613268 14.25631127111 5.3586982227645e-30 131.705824010345 124.831166505537 1.05507164354266 0.29303435067287 NMRAL1 other 1.77961531429681e-25 1 7.77547112123129e-26 14.25631127111 1.05507164354266 5.3522748047602e-26 557.601117332381 43.0314161379456 12.9580006278409 1.74772243929489e-26 153.062373199236 136.106582331472 1.12457730241488 0.26250670488195 UBALD1 other 7.72386777074945e-22 1 2.52895436965971e-22 12.9580006278409 1.12457730241488 0.856423571914141 12.1209945331424 21.7711204828268 0.556746472589847 0.578508836025399 10.4070209250416 69.567953852256 0.149595041233257 0.881279855393628 C16orf89 other 1 1 1 0.556746472589847 0.149595041233257 3.28722763359241e-10 157.489679293293 29.4920173299361 5.34007821612906 3.23003703020714e-07 -118.257338350761 51.7182927160268 -2.28656694063905 0.0235663005570482 TMEM251 other 3.80365109482978e-06 1 0.00363895971823136 5.34007821612906 -2.28656694063905 4.81184904309699e-15 229.303604058332 25.8797333362495 8.86035420377183 1.89807600333123e-15 72.9916736118449 47.1644969585422 1.5475978398753 0.123785122892355 ING1 other 6.45653904602754e-11 1 2.6559777514614e-11 8.86035420377183 1.5475978398753 0.0187873924470747 32.2600576245865 19.8637672256973 1.6240654281758 0.10646140105406 -56.5690099570689 36.4081647554735 -1.55374516504748 0.122352580624494 ADPRHL1 other 1 1 1 1.6240654281758 -1.55374516504748 4.33644695169088e-06 659.253614759852 203.336034144607 3.24218782732335 0.00145418921453044 -979.685176643606 448.208760532244 -2.18577873283922 0.0303420934565343 CMTM7 other 0.0371243223534256 1 1 3.24218782732335 -2.18577873283922 2.13152548656678e-08 126.849822884916 23.5182391654018 5.39367858251599 2.57135091378599e-07 -31.0451574813959 51.9874526750089 -0.59716635234024 0.551279028844495 FBXL2 other 0.000222680467581631 1 0.00291539766605055 5.39367858251599 -0.59716635234024 5.36324926385711e-14 570.624557212291 84.6075522488995 6.74436905506521 2.96698016477601e-10 -369.362893703489 187.026379294534 -1.97492404599143 0.0500763490882349 UBP1 other 7.05106380719294e-10 1 3.80604215537466e-06 6.74436905506521 -1.97492404599143 0.0001220320058985 104.568126837443 25.2582779240604 4.13995471709629 5.72088168139875e-05 65.3988382387053 59.8529818650974 1.09265797961591 0.276261469891832 PTPRD other 0.88570829881131 1 0.537247998700156 4.13995471709629 1.09265797961591 0.000358998099659739 15.9400714240179 15.9093988676347 1.00192795193825 0.31797074070667 -106.372837462848 37.6399621102081 -2.82606122586927 0.00534627729542745 LURAP1L other 1 1 1 1.00192795193825 -2.82606122586927 0.00133791871528982 75.0276404340062 29.2976579302634 2.56087502327295 0.0114349809452064 -47.3066657510416 59.9903514618256 -0.788571238512328 0.431615510744565 CNKSR3 other 1 1 1 2.56087502327295 -0.788571238512328 1.05854157305367e-15 257.440850387567 36.1294996271958 7.1255027897974 3.81751290727257e-11 9.22897586653081 60.8919179245912 0.151563231724118 0.879731096612561 CFDP1 essential 1.43612335216191e-11 1 5.03262726565743e-07 7.1255027897974 0.151563231724118 5.06783950225428e-11 305.269332363525 48.4390708694614 6.30213022017281 2.90415080866049e-09 82.9187514355717 89.1427590576504 0.930179324850675 0.353724679343659 ZDHHC7 other 6.06924458789972e-07 1 3.60724571943719e-05 6.30213022017281 0.930179324850675 0.152616657247942 -16.6445142025878 14.2364040830837 -1.16915157124302 0.244137412712558 -51.0591072659061 26.1993534608809 -1.94886898037938 0.0531167283469745 FAM92B other 1 1 1 -1.16915157124302 -1.94886898037938 8.65233371334862e-08 29.67855951984 7.37505346838645 4.02418228519409 9.01406856112798e-05 -20.564316310565 15.6489200660861 -1.3141045020181 0.190803827178841 C7orf31 other 0.000865752511357663 1 0.828933744881329 4.02418228519409 -1.3141045020181 0.112650407576084 -10.1320096653598 24.3680958661801 -0.4157899624575 0.678154004832421 -102.857253578918 52.9139985968896 -1.94385713244821 0.0537719130759215 JAZF1 other 1 1 1 -0.4157899624575 -1.94385713244821 8.18574682012361e-08 378.767636188334 85.4818674521201 4.43097053770484 1.76535510505878e-05 -47.2735599608486 158.306689958158 -0.298620102368026 0.765629891307554 CMIP other 0.000820375546312788 1 0.174929037360274 4.43097053770484 -0.298620102368026 0.590165232362039 4.91124324324322 26.844519887329 0.182951427846597 0.855072172344616 -108.297648648649 107.455318068973 -1.00783889150219 0.315082571606476 KCNJ16 other 1 1 1 0.182951427846597 -1.00783889150219 0.330235101180527 1.06830357241237 9.66169157126449 0.11057106972755 0.912096815691491 29.5936295542143 21.5671430173028 1.37216271670624 0.171957750031671 PID1 other 1 1 1 0.11057106972755 1.37216271670624 1.57225159434146e-12 807.427054340952 115.95564762034 6.96324043641768 8.42464989301635e-11 -96.2629626936222 258.839978221799 -0.371901447971591 0.710464527362076 TRIP12 other 1.98449596237779e-08 1 1.10034352252687e-06 6.96324043641768 -0.371901447971591 2.11143636294383e-07 51.0597245820139 11.2193148376586 4.55105550747427 1.05909505006119e-05 -28.0805759581122 25.0441204705381 -1.12124424537672 0.263885148086911 FBXO36 other 0.00204577069205628 1 0.1073075104722 4.55105550747427 -1.12124424537672 4.91600215106938e-24 292.973636954094 26.089255830405 11.2296662985939 9.39231894087338e-22 -171.219236149879 120.807622452871 -1.41728835212095 0.158418619292717 CEBPG other 7.06085388958095e-20 1 1.35080331007641e-17 11.2296662985939 -1.41728835212095 3.41399183487286e-05 186.704626555271 42.4774914502488 4.39537788557845 2.05817465001645e-05 23.6184030532456 159.951505311985 0.147659773549351 0.882805690407979 KCTD15 other 0.265813404263201 1 0.20277136651962 4.39537788557845 0.147659773549351 1.32058747139487e-22 71.5717429804503 6.39236950929421 11.1964339477542 9.25382692988796e-22 9.1502690899087 28.1081881883203 0.325537492086056 0.745207759039444 ZNF599 other 1.88791184910611e-18 1 1.33097792732579e-17 11.1964339477542 0.325537492086056 0.0119287207500156 26.3180116472546 10.8311943190745 2.42983468599642 0.0162556196372386 -38.0208402662229 35.5228859562222 -1.07031957688008 0.286150129989709 MCOLN2 other 1 1 1 2.42983468599642 -1.07031957688008 0.214271935346023 7.14556811623724 5.23767527287422 1.36426329315297 0.174462299671066 -12.7580031910921 23.4427877149369 -0.544218688759578 0.587073012052946 LGI4 other 1 1 1 1.36426329315297 -0.544218688759578 0.0274590509202945 161.208791733669 108.884452434275 1.48054922562042 0.140769713794843 -646.769969271919 351.005951124298 -1.84261824393651 0.0673075928378125 DDAH1 other 1 1 1 1.48054922562042 -1.84261824393651 2.36024923765433e-10 168.203007019332 92.0962181448161 1.82638343254054 0.0697545902657399 -463.679192223378 128.627351675 -3.60482577138762 0.00042285736220975 SREK1 other 2.74803818740094e-06 1 1 1.82638343254054 -3.60482577138762 5.12345214202877e-12 273.189292312635 43.731834851821 6.24692042394968 3.76059196589621e-09 37.6152301389664 63.2421464994126 0.594781047466752 0.552846067211686 CHD1 other 6.3582041082577e-08 1 4.65410861699315e-05 6.24692042394968 0.594781047466752 0.401733508509749 8.54355455263779 6.33267314339631 1.3491229310559 0.179227705008535 -2.10476298948591 24.6130151754806 -0.0855142279188401 0.931960850041163 ANKFN1 other 1 1 1 1.3491229310559 -0.0855142279188401 1.64878047308607e-09 109.837094074322 16.3133484972062 6.73295823313852 2.91311263429152e-10 -42.5539337127557 62.024806283341 -0.686079268323085 0.493668653797422 DGKE other 1.84003900796405e-05 1 3.7383974435863e-06 6.73295823313852 -0.686079268323085 4.47513536407892e-06 200.446991271686 48.2982225547516 4.15019395474557 5.47898137409342e-05 -310.890852460194 158.428257176183 -1.96234471047965 0.0515246568932509 HS2ST1 other 0.0382624073628748 1 0.515626937115932 4.15019395474557 -1.96234471047965 1.45833949403193e-08 545.53489338956 86.2776190158924 6.3230174825417 2.54293906037699e-09 306.927785531864 329.493582563717 0.931513697910978 0.353018112185847 MSI2 other 0.000153986067174831 1 3.16595913016935e-05 6.3230174825417 0.931513697910978 0.0167087020191964 45.8772790319014 17.2345442697799 2.66193746198125 0.00859930960256789 -10.2803812290188 52.9670586459457 -0.194090090932503 0.846362796993067 CACNA2D1 other 1 1 1 2.66193746198125 -0.194090090932503 3.05471517327841e-18 38.5931204868141 5.81848252189223 6.63284977510997 5.11104617313248e-10 -24.245541549991 12.1482481862024 -1.99580558269531 0.0476956880340773 ZUFSP other 4.26865898313925e-14 1 6.51198392918809e-06 6.63284977510997 -1.99580558269531 3.42728465297798e-09 28.2987482695387 4.26774806181079 6.63083852647377 5.16566170651305e-10 -7.66952721263469 16.5489732230044 -0.463444294052844 0.643691875633686 GDPD1 other 3.76007399278215e-05 1 6.57950331558567e-06 6.63083852647377 -0.463444294052844 9.57974957060018e-14 120.490947172299 33.6211650271213 3.58378262844556 0.000451464150914753 -265.031490025095 69.9619979140039 -3.78822071878032 0.000215734552941878 NUS1 essential 1.25025311645903e-09 1 1 3.58378262844556 -3.78822071878032 0.847669106704971 0.460232537286683 13.4884220650463 0.034120561698564 0.972825485449157 22.9880817168305 41.4282471359592 0.554889074630367 0.579780833439197 SEMA3D other 1 1 1 0.034120561698564 0.554889074630367 7.69093012074573e-09 216.433276649065 51.649416074003 4.19043027202787 4.64667468926617e-05 -152.485776980837 74.1324550660092 -2.05693682807429 0.0413576220291231 PPP2R5E other 8.25082983353602e-05 1 0.441062361505145 4.19043027202787 -2.05693682807429 0.779445883522453 3.24459159332073 5.01377840210128 0.647135021356532 0.51849566472967 6.83445751418952 14.0640339425323 0.485952859763857 0.62768247821759 SLC5A10 other 1 1 1 0.647135021356532 0.485952859763857 0.167921250003147 -12.3557263526368 6.53540085050675 -1.89058431690211 0.0605341600409469 -15.1032493721939 19.4628594786151 -0.776003618008376 0.438921734944906 AK5 other 1 1 1 -1.89058431690211 -0.776003618008376 2.3887801617628e-06 47.9188492454214 9.39477462074048 5.10058529127807 1.09750066541963e-06 25.5079217315026 28.5220212112483 0.894323776796119 0.372705793270379 CABYR other 0.0210260429838361 1 0.0119693422570665 5.10058529127807 0.894323776796119 7.18236394817308e-16 163.300363978777 22.5030127510477 7.25682226577303 2.60812399569288e-11 -119.412961990475 60.2918578871207 -1.98058189240148 0.0496265946735863 IMPACT other 9.7766338062532e-12 1 3.45028723390211e-07 7.25682226577303 -1.98058189240148 4.97746723809681e-10 37.8755916624131 5.50631752513132 6.87857020405118 1.96761919308131e-10 27.3379499360895 16.8362598128607 1.62375433973802 0.106726938579608 ANKRD29 other 5.70467520158275e-06 1 2.54157371170313e-06 6.87857020405118 1.62375433973802 0.00787710214622058 46.8467849185652 27.2945363731479 1.71634294417445 0.0881775097677453 -63.3571736990277 52.7156272150954 -1.20186701830392 0.231321771374394 SDHAF4 other 1 1 1 1.71634294417445 -1.20186701830392 0.186196458221634 53.1826568265681 43.9345113893141 1.21049842469634 0.228127383903578 -54.5340713407136 103.309195820524 -0.527872382584936 0.598423573088975 CHST9 other 1 1 1 1.21049842469634 -0.527872382584936 0.0526529692465086 -123.698285520835 430.970815369648 -0.287022418013938 0.774486050430269 -2873.59537808015 1216.4070146356 -2.36236337303677 0.0194254263875826 THY1 other 1 1 1 -0.287022418013938 -2.36236337303677 0.0206232323958923 28.9437570303712 45.0828241436658 0.642012952385945 0.521813141319575 -141.790469373146 83.490369090813 -1.6982853341913 0.0914604592247655 DNAAF1 other 1 1 1 0.642012952385945 -1.6982853341913 0.41030119288645 -5.56190577516417 6.65668414777995 -0.835536980828376 0.404709875425272 -16.3993916298324 12.2511916773806 -1.3385956290367 0.182675143921201 C16orf74 other 1 1 1 -0.835536980828376 -1.3385956290367 1.48414584435516e-14 106.393071093468 14.3111756292355 7.4342649304173 7.13683299590298e-12 -65.058312281968 40.0334598210451 -1.62509841949178 0.106213304249382 TBCEL other 1.97302348548574e-10 1 9.54622781531983e-08 7.4342649304173 -1.62509841949178 0.177985231370033 -31.8044044956625 22.9622479483759 -1.38507364641152 0.168059380250362 3.72643979430485 39.788649401411 0.0936558503584869 0.925505880433352 JPH3 other 1 1 1 -1.38507364641152 0.0936558503584869 0.0168695385121664 263.843628750667 91.6287833672143 2.8794841430261 0.00457450957819285 145.576826772099 363.346078997624 0.400656110487574 0.689251112902048 ANKH other 1 1 1 2.8794841430261 0.400656110487574 6.90285921430702e-10 97.6407146595844 14.6058707112772 6.68503210727425 4.33411083247604e-10 -17.2506033847705 58.1090190055876 -0.29686619529942 0.766982098617031 OTULIN other 7.85269264219567e-06 1 5.52989201115618e-06 6.68503210727425 -0.29686619529942 0.255640139895459 27.4645926646812 23.423264180481 1.17253481210223 0.24278132514269 -45.1282332387496 62.4265379323426 -0.722901425154463 0.470829842081712 UBASH3B other 1 1 1 1.17253481210223 -0.722901425154463 0.516050390562918 -16.295242736494 14.5000609361773 -1.12380512111075 0.262915230317579 -4.11196240678307 38.9483992465196 -0.105574618888875 0.916062818127269 ROBO4 other 1 1 1 -1.12380512111075 -0.105574618888875 0.00468466466802336 76.0380401599221 29.3316260016078 2.59235680134999 0.0105078676571844 -93.7691166679891 78.8278809268243 -1.18954252690155 0.23617043546985 ROBO3 other 1 1 1 2.59235680134999 -1.18954252690155 3.08812453811412e-11 98.158724452835 17.8283537950006 5.50576489458946 1.49270029047496e-07 -155.555660439488 48.7795638937016 -3.18895143832094 0.00172796752601042 TBRG1 other 3.7289103797728e-07 1 0.00171869511445287 5.50576489458946 -3.18895143832094 0.151347142198981 71.8461357169347 92.0209580964144 0.780758396817151 0.436235160907608 -357.423260214815 243.106776239735 -1.47023158195455 0.143695892456034 NRGN other 1 1 1 0.780758396817151 -1.47023158195455 0.00497560023355751 42.9847763239985 16.7803895264491 2.56160777771256 0.011411923890193 -100.854336001687 69.8858645853511 -1.44312925940144 0.15108311740512 RETREG1 other 1 1 1 2.56160777771256 -1.44312925940144 0.760284916522978 -7.06419267474851 16.5292914196534 -0.427374198651319 0.669715610755909 -46.3653748602871 68.4359903915099 -0.677499873897334 0.499125573828219 CDH12 other 1 1 1 -0.427374198651319 -0.677499873897334 2.23302990305676e-13 276.089013932844 39.0323752718669 7.07333366237231 5.07059155333643e-11 -493.93521424538 173.170886655988 -2.8522993892536 0.00494092494828065 TOMM70 other 2.88753096764269e-09 1 6.66072906446274e-07 7.07333366237231 -2.8522993892536 0.0597021714655228 140.985918567841 59.451243915509 2.3714544773564 0.0189628319069482 41.494329828136 252.457223366651 0.164361824450048 0.869663252431846 ABI3BP other 1 1 1 2.3714544773564 0.164361824450048 0.785398208699431 -1.66418889374728 9.66201871959645 -0.172240288706125 0.863479258801975 24.4246673746018 41.4391218134067 0.589410834635489 0.556466543293144 ANGPT1 other 1 1 1 -0.172240288706125 0.589410834635489 2.92641902854703e-05 332.953843491227 71.4705537310066 4.65861569709344 6.77545783297714e-06 258.9307053279 289.220304160728 0.895271533854708 0.372021252344121 PITPNC1 other 0.229782422121513 1 0.0698007665953305 4.65861569709344 0.895271533854708 6.21836837218096e-10 131.621687311849 30.1537568109296 4.36501786948621 2.34665038230745e-05 -350.732307654346 93.6075309999013 -3.74683857065641 0.000254326208577241 CC2D1B other 7.09391463898404e-06 1 0.229619739908784 4.36501786948621 -3.74683857065641 0.00054351050181393 255.318801089918 67.3466414149628 3.79111408862614 0.000214365730578368 342.876566757494 270.345949995347 1.26828815731619 0.206596693456769 PRKCA other 1 1 1 3.79111408862614 1.26828815731619 4.72059581903569e-05 691.010399466798 153.640822845704 4.49757028547519 1.35113734429545e-05 102.663911338266 284.536376071621 0.360811200155387 0.718738271889043 LRRK1 other 0.360370284825184 1 0.13541098464529 4.49757028547519 0.360811200155387 8.94194958404084e-05 44.9625261765679 10.1323539547813 4.43752028178514 1.7183908624557e-05 -9.6869558029318 40.4501793487741 -0.239478686099457 0.811050804183068 CEP112 other 0.659647620814693 1 0.170515925281479 4.43752028178514 -0.239478686099457 0.0205831759256385 -31.5053831445368 18.7525856739439 -1.68005541701443 0.0952089272503269 -109.820433784219 39.3405746436658 -2.79153100276082 0.00599008449668171 GAL3ST2 other 1 1 1 -1.68005541701443 -2.79153100276082 0.458199977549658 -4.58939255388636 4.14549722902528 -1.10707891004077 0.26994242808122 9.48058785107766 16.8182318452764 0.563708952183363 0.573751432615023 ABCA9 other 1 1 1 -1.10707891004077 0.563708952183363 0.424114178757283 -1.14998040496407 3.31373250606119 -0.347034772076692 0.729026991167388 -17.1174003919008 13.4437724791991 -1.27325870907037 0.204796373642539 ABCA6 other 1 1 1 -0.347034772076692 -1.27325870907037 0.337813817378931 1.37858915741346 1.62738796963205 0.847117702194366 0.398210836808001 -7.88717178314834 6.6022932023334 -1.19461095432127 0.234029285119321 ABCA10 other 1 1 1 0.847117702194366 -1.19461095432127 5.05654039673256e-05 60.5874853037232 13.2200008332081 4.58301675379096 9.25734749037645e-06 -9.58694970607548 53.6333826135301 -0.178749674902231 0.858363262129733 ABCA5 other 0.384754287606811 1 0.0942768268419938 4.58301675379096 -0.178749674902231 0.706056754849993 23.9856257154985 29.046929399532 0.825754260823349 0.410196526999936 36.0267676832642 59.9756222170966 0.600690186303634 0.5489125344545 ENPP3 other 1 1 1 0.825754260823349 0.600690186303634 0.153117877323757 -2.83022242326874 26.9540329634535 -0.105001816503905 0.916511003578869 -76.8775261328103 47.0479954227233 -1.63402341464435 0.104296599751536 C4orf19 other 1 1 1 -0.105001816503905 -1.63402341464435 1.08495256737131e-05 2180.80985052553 520.762732822054 4.1877225712899 4.72589503013206e-05 417.808139271021 882.133255748714 0.473633815014042 0.636431804993088 UCHL1 other 0.0893241448716797 1 0.448440179409231 4.1877225712899 0.473633815014042 8.73760714281318e-10 342.169644709474 55.681674234691 6.14510338297791 6.39440974140126e-09 -143.371600163841 173.684250734168 -0.825472658331459 0.410363857096534 MIA3 other 9.89184504637881e-06 1 7.85105628049247e-05 6.14510338297791 -0.825472658331459 5.50972361295759e-07 51.7314290717592 11.1558853619413 4.63714240451439 7.42372332470659e-06 -48.8347382111566 35.5140581707466 -1.37508188944125 0.171077684915857 DISP1 other 0.00513836824144425 1 0.0761674013114896 4.63714240451439 -1.37508188944125 0.464480733038246 6.47702373553594 28.1247567159859 0.230296169347999 0.818175415314095 -192.430141978772 157.08280221195 -1.22502361346425 0.222486510135955 TNIK other 1 1 1 0.230296169347999 -1.22502361346425 1.32403478016338e-05 -11.6267741935483 23.51054102794 -0.494534523035052 0.621642736804441 -170.077710718002 45.1404698282028 -3.7677434764257 0.000235114132568909 FAM167A other 0.108054478409133 1 1 -0.494534523035052 -3.7677434764257 8.48549265491246e-19 173.864677419355 28.5975095226134 6.07971394438639 9.3150023245541e-09 -89.6647450572323 54.907499331179 -1.63301454536132 0.104535721837914 NEIL2 other 1.18975092514528e-14 1 0.000113531248331665 6.07971394438639 -1.63301454536132 0.00545557861043724 160.765938176656 49.2586584551838 3.26370922835674 0.00135477033475704 152.389541100764 104.055795351892 1.46449835480492 0.145096255396357 PGM5 other 1 1 1 3.26370922835674 1.46449835480492 0.583697550481309 5.96167526944988 5.79790917916116 1.02824571500315 0.305489478209959 9.73411125260504 18.1218108237746 0.537148927734889 0.591960645422192 WNT3A other 1 1 1 1.02824571500315 0.537148927734889 0.0013931460379597 415.654351672224 163.108547298469 2.54832967711758 0.0118947628848089 -749.342558116371 517.090061502033 -1.44915289212811 0.14951530531742 OBSCN other 1 1 1 2.54832967711758 -1.44915289212811 3.52882092814219e-09 132.633067581729 44.8443658649663 2.95763057462132 0.00359941386336362 -173.084726303245 87.3318519654673 -1.98191979681922 0.0493033861955484 LONRF1 other 3.86758773724384e-05 1 1 2.95763057462132 -1.98191979681922 4.65025858735449e-09 799.671739865857 147.455716833916 5.42313147998565 2.15651365461631e-07 -825.229963375891 478.562028565125 -1.7243949877306 0.086592276989658 ENAH other 5.05855129132422e-05 1 0.00245756296080075 5.42313147998565 -1.7243949877306 1.08116197111541e-05 65.1189932336336 15.5358189059098 4.19153915400382 4.61223717181214e-05 -43.1648044793058 48.4610126304283 -0.890711979307732 0.374446635559625 CCSAP other 0.089044499941065 1 0.438024164206999 4.19153915400382 -0.890711979307732 3.19009611124741e-05 500.966631099039 117.951242294854 4.2472348858075 3.69493490180488e-05 200.488681006887 179.915672165869 1.11434806425341 0.266832881105099 SH3RF1 other 0.249242209171761 1 0.354048662290944 4.2472348858075 1.11434806425341 0.505569998225298 4.53715505412403 51.3760328844359 0.0883126780989456 0.9297421605499 -187.193271332012 168.653170652292 -1.10993034170667 0.268748027484117 GBP5 other 1 1 1 0.0883126780989456 -1.10993034170667 0.0102868935862903 247.385042999656 106.042553978736 2.33288461770982 0.0209396656500233 -132.647155142759 192.808011661825 -0.687975328408114 0.49249659701692 BUB3 essential 1 1 1 2.33288461770982 -0.687975328408114 0.144242647881083 -2.35677857621793 8.61074662406098 -0.273702000431924 0.784687668043345 -50.9905383714079 26.0696177237462 -1.95593732565407 0.0523180957021286 CCDC173 other 1 1 1 -0.273702000431924 -1.95593732565407 0.0662489679975231 32.9952855060326 18.4318941418881 1.7901190866243 0.0753868415551341 -62.2686020905059 59.9934174884734 -1.03792390394279 0.30092193336248 FAM69A other 1 1 1 1.7901190866243 -1.03792390394279 0.934217114956813 -89.7264177677019 351.188516615367 -0.255493598231667 0.798689576111583 -405.521306365344 1257.04919060441 -0.322597802374276 0.747446099434769 ATP5G3 other 1 1 1 -0.255493598231667 -0.322597802374276 3.63059529801885e-09 56.5744933043032 9.95574409083924 5.68259818533906 6.5727411324749e-08 10.8735677597787 19.7654249502336 0.550130735218533 0.583037209541553 SRSF12 other 3.97441267274123e-05 1 0.000771442626718579 5.68259818533906 0.550130735218533 0.40689958780412 97.3023123328077 104.285189941582 0.933040562972691 0.352231719693028 -27.7004260284695 169.661326072438 -0.163268946846747 0.870516656708372 PDLIM3 other 1 1 1 0.933040562972691 -0.163268946846747 0.105258724563464 -66.8223269186684 67.9201090764513 -0.983837155553634 0.326709304438842 -241.757237674775 115.302944274739 -2.09671348112955 0.0376220458017413 SORBS2 other 1 1 1 -0.983837155553634 -2.09671348112955 0.00187227712063491 107.241182402469 64.6200467298935 1.65956522518048 0.0991338504900524 -506.184795946882 217.901178302149 -2.32300164639307 0.0215506268288673 ELOC other 1 1 1 1.65956522518048 -2.32300164639307 0.960902799460889 0.712665015282205 9.13720428133941 0.0779959595231613 0.937935909958141 8.67272437053282 30.9002380575159 0.280668529297086 0.779353983209559 LY96 other 1 1 1 0.0779959595231613 0.280668529297086 0.00274677843257484 196.212749276294 108.384100008949 1.81034625244933 0.0725696536437387 -435.088533290448 222.818707176085 -1.95265711216345 0.0530257694953134 CXADR other 1 1 1 1.81034625244933 -1.95265711216345 0.000185352400360256 243.229273882276 183.309624998206 1.32687671956482 0.186893383663962 -1176.57840141525 376.852450236342 -3.12211954752413 0.00221677707157769 BTG3 other 1 1 1 1.32687671956482 -3.12211954752413 5.83553878217425e-06 143.404028626568 45.6636564749118 3.140441210733 0.00209200236043726 -220.664683177871 93.8764717318558 -2.3505856058179 0.0202600905440076 C21orf91 other 0.0492752894766794 1 1 3.140441210733 -2.3505856058179 0.00693666972243301 137.833947025795 62.9868130925693 2.18829847484467 0.0304629219576191 -154.472231263732 129.567745414415 -1.19221208001776 0.23538368278421 CHODL other 1 1 1 2.18829847484467 -1.19221208001776 0.649379181424802 -4.27209302325581 5.20409650843968 -0.82090964614657 0.413212181412674 0.298372093023263 9.85176842533008 0.030286145607738 0.975885652406392 NCAM2 other 1 1 1 -0.82090964614657 0.030286145607738 2.78209632990842e-08 62.7241449649827 11.5671484574872 5.4226108703898 2.2631326819103e-07 2.85842115999196 30.4381867408323 0.093909048667391 0.925305080199222 L3MBTL4 other 0.000288253000741812 1 0.00257567130528211 5.4226108703898 0.093909048667391 0.764829084678953 2.06197423064635 3.06200773116211 0.673405951807894 0.501705024461195 4.52832854151139 7.69009535213273 0.588852066737446 0.556828884425306 PDE1C other 1 1 1 0.673405951807894 0.588852066737446 0.000362895858177084 75.7430986612904 32.1055525005361 2.359190008022 0.019815806978057 -124.260862645233 62.2534953696914 -1.99604635703284 0.0480346880058035 MRPL39 essential 1 1 1 2.359190008022 -1.99604635703284 0.55491170182641 7.8339169186694 19.6793488066972 0.398078056119591 0.691230683624161 -28.1470635046953 38.1587655218145 -0.737630348356113 0.462078747018938 JAM2 other 1 1 1 0.398078056119591 -0.737630348356113 0.010526182520482 -10.7233230763793 253.172659114503 -0.0423557706186964 0.966280575292858 -1366.22258475251 490.908323775272 -2.78305035499446 0.00619462073795266 ATP5J other 1 1 1 -0.0423557706186964 -2.78305035499446 2.57621461074095e-10 225.665260756538 39.6424277865763 5.69251868153628 8.02705119560809e-08 -120.64571064778 76.8676911762769 -1.56952431901602 0.118975490313181 GABPA essential 2.99459186352528e-06 1 0.000936917415551376 5.69251868153628 -1.56952431901602 0.103268022177126 155.987483862982 374.694122895361 0.416306193055886 0.677877781210407 -1247.34593347127 726.541580130959 -1.71682663123897 0.0884109108209453 ADAMTS1 other 1 1 1 0.416306193055886 -1.71682663123897 0.119102514488094 74.2145151358818 36.120793888944 2.05462026565805 0.0418886351836354 83.5268518364426 69.647033559361 1.19928800363409 0.232564339610127 ADAMTS5 other 1 1 1 2.05462026565805 1.19928800363409 4.96340658414705e-10 76.7619047619048 15.6561130251669 4.90299888858183 2.33530155524836e-06 -61.0523809523809 30.446282356073 -2.00524912166175 0.046654737264249 TSEN2 essential 5.68955296740776e-06 1 0.0249200028960553 4.90299888858183 -2.00524912166175 0.0031399559174012 319.316020751293 94.5400138230355 3.37757535501321 0.000928845534648947 457.58451786972 364.900981668201 1.25399640137388 0.211768436988584 SLFN13 other 1 1 1 3.37757535501321 1.25399640137388 0.00543035136351899 569.145812301187 173.723535470032 3.27615835563838 0.00129516253409675 615.904411512603 334.565960983334 1.84090578043976 0.0675228688690978 WNT7A other 1 1 1 3.27615835563838 1.84090578043976 1.35844899833603e-11 197.947782498301 37.0493758748629 5.34281017760959 3.18915290656356e-07 -152.500359012168 71.1438651698265 -2.14354897148385 0.0336189432916652 XPC ts 1.66179065966447e-07 1 0.00359449424098779 5.34281017760959 -2.14354897148385 1.26867074081154e-11 75.1742634629316 16.7300514274157 4.4933671476791 1.35327685582463e-05 -104.151020284955 31.6625198543054 -3.28941034270817 0.00123946510708115 CCDC174 essential 1.55399479042005e-07 1 0.135598340953628 4.4933671476791 -3.28941034270817 0.0293951835092235 -40.5390408999904 85.957160225048 -0.471619127410137 0.637853421129373 -416.524738297263 164.237283950671 -2.53611560224271 0.0121856948490939 FGD5 other 1 1 1 -0.471619127410137 -2.53611560224271 6.76164684070235e-05 188.004391677015 41.7471433787797 4.50340733427471 1.30815667011742e-05 177.95281218766 130.628657429813 1.36228003631802 0.175085834179873 FLCN other 0.506785430710641 1 0.13135201124649 4.50340733427471 1.36228003631802 0.000409954289063679 90.7671222780948 27.5080780945549 3.29965335877324 0.00119640618763975 -23.8064454560743 52.2894727051391 -0.455281803859815 0.649531529383867 DPH3 essential 1 1 1 3.29965335877324 -0.455281803859815 4.23461541540074e-07 21.4196991944124 11.0231414518554 1.94315742821272 0.0537745770135711 -78.1120282550895 20.9536359497894 -3.72785078648245 0.000268601495678638 OXNAD1 other 0.0039932423367229 1 1 1.94315742821272 -3.72785078648245 2.47243209475825e-20 266.210991120711 48.8928641126541 5.44478209554944 2.03947550353648e-07 -300.194576433885 98.8548105293172 -3.03672198476226 0.00281522639988461 CXXC1 essential 3.49849141408292e-16 1 0.00232683760198477 5.44478209554944 -3.03672198476226 1.57819941095695e-05 55.2615661147325 18.9643641987138 2.91396882783344 0.00410421872892241 -27.3376481924538 38.3125890210332 -0.713542177414471 0.476597328994531 SKA1 essential 0.127644768358198 1 1 2.91396882783344 -0.713542177414471 6.54379608063691e-18 365.404951978066 45.4222001869716 8.04463347160523 2.35179091501914e-13 -168.253492451367 121.557104133386 -1.38415186550298 0.168354263873725 PPP4R1 other 9.11419918111108e-14 1 3.22007212084421e-09 8.04463347160523 -1.38415186550298 0.142828050711663 -9.54055511684506 104.284518453257 -0.0914858241506036 0.927229449438425 -487.454354319194 277.360119750278 -1.75747816505875 0.0808900727940945 APCDD1 other 1 1 1 -0.0914858241506036 -1.75747816505875 0.148372362734328 0.17774874261701 10.4009774535323 0.0170896190681236 0.986387982895855 47.1525350684679 27.6629397615209 1.70453811037311 0.0903648821262468 PIEZO2 other 1 1 1 0.0170896190681236 1.70453811037311 0.207589997099473 4.96163274006182 2.93584218168604 1.69002025075217 0.0931152121076232 8.84435947991045 8.92189013427618 0.991310063988809 0.323141303847121 CCDC144B other 1 1 1 1.69002025075217 0.991310063988809 4.78009424601612e-10 60.4151929326985 22.171533288868 2.72489918245898 0.00720760534207065 -237.176528039111 58.0304350683768 -4.08710580507707 7.13669074305946e-05 MPPE1 other 5.4851581473035e-06 1 1 2.72489918245898 -4.08710580507707 0.000590893684397116 44.0855728429985 11.3289746409261 3.89140008167541 0.000149854623246905 -4.76661951909442 46.854264112589 -0.101732886203066 0.919105473969076 USP43 other 1 1 1 3.89140008167541 -0.101732886203066 0.000326893517134871 165.77020405178 45.2244583142699 3.66549894085683 0.000339899545806448 -225.404139545089 172.961828309167 -1.30320164714137 0.194463696706166 RAB6B other 1 1 1 3.66549894085683 -1.30320164714137 5.76758730414804e-09 132.813970026946 21.1743457433619 6.27240017881461 3.25985159380597e-09 -120.615608954075 86.1850326707168 -1.39949600547122 0.1636245515941 EME1 other 6.23591539324486e-05 1 4.04123802084126e-05 6.27240017881461 -1.39949600547122 0.195200865432666 3.90816015335688 9.74605380264887 0.400999238511764 0.68898013920279 -63.3944582407529 37.3912646745287 -1.69543498441597 0.0920270008049819 EPHB1 other 1 1 1 0.400999238511764 -1.69543498441597 0.256875068059018 -0.474710888064639 51.6391087174409 -0.00919285595462471 0.992677729514953 -312.225030391821 199.028687968004 -1.56874385084634 0.118857710265005 ACSS1 other 1 1 1 -0.00919285595462471 -1.56874385084634 4.59434078395186e-10 300.01675666648 42.8322683453833 7.00445641233048 6.85170055545e-11 168.72052274119 169.126632059587 0.997598785516796 0.320009012879611 ANKRD40 other 5.27614095629031e-06 1 8.96750568697296e-07 7.00445641233048 0.997598785516796 1.25961016596263e-10 45.8470535921429 6.37615195905554 7.19039538056021 2.6782362041551e-11 4.3791470110577 24.4206405042084 0.179321546062768 0.857922486141349 ZNF18 other 1.48508038566995e-06 1 3.54196737999512e-07 7.19039538056021 0.179321546062768 0.0129756065236997 169.409173502573 74.1567765949528 2.28447326436386 0.0237463940571851 -129.492211673932 189.796467387402 -0.682268819100935 0.496121205807715 VOPP1 other 1 1 1 2.28447326436386 -0.682268819100935 0.88308733127644 -9.76098191214456 30.8639138512989 -0.316258720756304 0.752226216441195 -23.1255652454778 46.3962304671884 -0.49843629563467 0.618874116872324 DKK2 other 1 1 1 -0.316258720756304 -0.49843629563467 0.00323353810592272 28.2105943152458 23.387796336022 1.20621002124068 0.229551044086798 -56.6175306847542 35.1577442236826 -1.6103857609447 0.109322398246086 CYP2U1 other 1 1 1 1.20621002124068 -1.6103857609447 1.00623948769672e-08 20.5207630656597 14.7940751672845 1.3870933352454 0.167457334256935 -105.973889908344 28.6561773592 -3.69811676484201 0.000303477567189372 RSPH10B other 0.00010723494220384 1 1 1.3870933352454 -3.69811676484201 2.09048994337133e-14 95.0810809558454 14.9626925213851 6.35454353018032 2.33931116714904e-09 -4.80111116774559 29.399187781859 -0.163307612556159 0.870494603688768 FBXL18 other 2.77303490988208e-10 1 2.916185300968e-05 6.35454353018032 -0.163307612556159 0.0969082451912193 -637.559247155653 306.20879157151 -2.08210627749648 0.039234852627854 -1136.92647058823 962.394735890407 -1.18135150597676 0.239555517893452 PROM2 other 1 1 1 -2.08210627749648 -1.18135150597676 1.59530434033197e-07 44.595025756386 9.02168904606733 4.94309053755577 2.05860055661784e-06 8.97943482369854 19.3516166245711 0.464014712460622 0.643318979079629 AK9 other 0.00156148834559199 1 0.0220620221652734 4.94309053755577 0.464014712460622 0.0634877107443018 183.329157649599 82.806199841328 2.21395448651057 0.0283111872787734 527.767229270658 360.288686134601 1.46484541308491 0.145014934196818 KLF10 other 1 1 1 2.21395448651057 1.46484541308491 0.274538911865834 -15.474906275516 11.0239568348309 -1.40375243729384 0.162459497653386 -39.9561778641484 31.8415358017553 -1.25484455627124 0.211486797568663 PTPRN2 other 1 1 1 -1.40375243729384 -1.25484455627124 2.44478555894149e-08 789.340595662028 144.808978852092 5.4509092041058 1.96578517901497e-07 -725.195208805438 615.259413584491 -1.17868202061381 0.240354642480038 AZIN1 other 0.000254184354563146 1 0.0022453198314709 5.4509092041058 -1.17868202061381 7.94932166345842e-12 367.949789575915 52.0377620013688 7.070822714594 5.14021614827407e-11 -177.802417179238 221.09625512872 -0.804185566488783 0.422537568409407 ATP6V1C1 essential 9.80469333970961e-08 1 6.75167391075799e-07 7.070822714594 -0.804185566488783 9.42510688329623e-09 64.3664791150976 11.4432314659614 5.62485162574571 9.00035876666628e-08 -53.7555557585334 45.6429453999201 -1.1777407283323 0.240790345797092 OTUD6B other 0.00010065071640672 1 0.00104836178914129 5.62485162574571 -1.1777407283323 3.8774202642249e-19 271.785932201743 34.8181928563601 7.80585980791639 8.66386932750811e-13 -55.6854072138076 72.9658203596618 -0.763171125046276 0.446536474300658 CDK19 other 5.45165289150021e-15 1 1.177939673768e-08 7.80585980791639 -0.763171125046276 2.9560202837281e-13 152.089383415468 37.594508929976 4.04552121424838 8.25746159123503e-05 -253.25967172403 78.5519887252912 -3.22410260814299 0.00154487277450497 GTF3C6 essential 3.80912773761202e-09 1 0.761998555639169 4.04552121424838 -3.22410260814299 0.00297121286357188 63.5383846614572 28.5324678248626 2.22688009503654 0.0274156111028948 -71.1740281085902 67.7486235788433 -1.05056050365009 0.29511700469864 TTC39B other 1 1 1 2.22688009503654 -1.05056050365009 7.35885103146759e-14 329.47719619206 55.8052771056097 5.90405089412125 2.33030779128518e-08 -42.1408618797968 107.719207487936 -0.391210285171438 0.696204436888039 AGPAT5 other 9.63420777039737e-10 1 0.000279194176473878 5.90405089412125 -0.391210285171438 3.14690798942252e-21 627.553248095944 81.6191449931789 7.688799584318 1.4874151420294e-12 -329.990244799026 141.78126163893 -2.32746020866568 0.0212094863391599 MMS19 essential 4.47616192415459e-17 1 2.01440632685042e-08 7.688799584318 -2.32746020866568 9.95020117923401e-10 189.879594720336 48.552012397184 3.91084911510999 0.000136253964041798 -196.416509862035 84.3400843436548 -2.32886309505822 0.0211329832563212 PI4K2A other 1.12347721514731e-05 1 1 3.91084911510999 -2.32886309505822 0.00237634384836625 278.850653065445 121.126577886745 2.3021425844803 0.0226325869308274 -178.737455055082 210.409935465802 -0.849472505466038 0.396903717092106 MARVELD1 other 1 1 1 2.3021425844803 -0.849472505466038 1.20844450669664e-11 103.908963710928 35.1115308941631 2.95939712865673 0.0035571251120241 -247.021920483395 60.992517731774 -4.05003645807375 8.0048143830003e-05 ZFYVE27 other 1.48155296521008e-07 1 1 2.95939712865673 -4.05003645807375 0.21186339831873 14.188186235655 11.301739636952 1.25539843346466 0.211187643856005 -5.56923872212836 19.6323412181745 -0.283676748495624 0.777029494667105 GOLGA7B other 1 1 1 1.25539843346466 -0.283676748495624 0.736464549739478 -3.36556196512322 84.1766705524203 -0.0399821226360735 0.968161263027869 97.3638541528291 159.729376993084 0.609555086144514 0.543091233678145 GPR78 other 1 1 1 -0.0399821226360735 0.609555086144514 3.67643075210218e-05 77.744381848573 19.0240636832492 4.08663380984301 7.10618573091475e-05 19.8502674655092 35.8853265461592 0.553158334506886 0.580978485930369 TRMT44 other 0.284666033135272 1 0.660306778116599 4.08663380984301 0.553158334506886 0.00155626959487607 7.62101551144861 29.7514367690484 0.256156217617599 0.798165543777572 -143.2453525221 50.9631440149889 -2.81076364676343 0.00557238789952428 SLC25A28 other 1 1 1 0.256156217617599 -2.81076364676343 2.09085585841293e-05 180.043718757683 50.893801206969 3.53763551725095 0.000560428118168025 -157.719351798738 106.142919359112 -1.48591496023515 0.139722728985977 HSPA13 other 0.167038474528609 1 1 3.53763551725095 -1.48591496023515 0.914296596630345 -0.769481539670077 14.1029741584334 -0.0545616499772096 0.956570815147633 -11.6871563236449 28.9592966423011 -0.403571829385296 0.687185590701298 SAMSN1 other 1 1 1 -0.0545616499772096 -0.403571829385296 2.32018632560095e-05 243.253185950327 67.9841689876725 3.5780857451451 0.000489574212758279 -205.761615334551 140.733519330465 -1.46206544335319 0.146174122114664 USP25 other 0.184594024064812 1 1 3.5780857451451 -1.46206544335319 6.60724879522292e-05 58.317955906716 16.026485810452 3.63884862823032 0.000372509323473124 -10.9062243987693 26.5818503962404 -0.410288382343458 0.682160974533188 ZCCHC10 other 0.495940094569433 1 1 3.63884862823032 -0.410288382343458 0.000695522407759908 53.7170369043353 16.1102857639536 3.33433172393044 0.00109086573392235 19.2871730562523 24.029515463431 0.802645108912172 0.423521225717587 C16orf87 other 1 1 1 3.33433172393044 0.802645108912172 4.09313200738209e-06 451.805309077223 133.005112839234 3.3969018140177 0.000874077046960287 -1116.37590366218 432.284309991801 -2.58250387038881 0.0107717023259509 MOV10 other 0.0351681902074269 1 1 3.3969018140177 -2.58250387038881 0.216504438995878 -35.979163778249 287.830071985348 -0.125001406316157 0.900690928409564 -1586.68700112896 935.486023108529 -1.69610978885238 0.0919534293793712 RHOC other 1 1 1 -0.125001406316157 -1.69610978885238 0.00499489749537368 51.5092198300619 18.7964288010071 2.74037267266971 0.00688747420561349 -51.9076036364356 61.0908940348384 -0.849678245121673 0.39686717845572 PPM1J other 1 1 1 2.74037267266971 -0.849678245121673 0.25330520640925 -145.368073870878 104.206924051963 -1.3949943844268 0.165013270558847 -403.363844622098 289.964779998938 -1.39107875316297 0.166195143059975 DBI other 1 1 1 -1.3949943844268 -1.39107875316297 0.000723485477521134 345.149788593169 106.060002956109 3.25428794053496 0.00140112745683018 -330.046081397643 345.203985249865 -0.956090009096361 0.340544902784258 SLC16A1 other 1 1 1 3.25428794053496 -0.956090009096361 1.10983220273318e-05 32.4430849397292 24.5856425906962 1.31959475210164 0.189035876938544 -94.881824777798 36.5716054819711 -2.59441234606374 0.0104412763498128 HEATR3 other 0.0913058953188587 1 1 1.31959475210164 -2.59441234606374 0.00589419379161369 35.6378837092274 12.4750416930517 2.85673463753448 0.00489669493859555 -51.0213059734078 49.634160610888 -1.02794739238958 0.305651650903608 TRIM74 other 1 1 1 2.85673463753448 -1.02794739238958 1.02344169918849e-06 101.825932753577 57.0101495015058 1.78610183702268 0.0760377290308928 -596.109265418987 150.299369934918 -3.96614613672107 0.000111311611035563 NIFK other 0.00933174141320069 1 1 1.78610183702268 -3.96614613672107 3.17062140192705e-17 622.636244100441 95.2029259357997 6.54009567437367 8.69961171779344e-10 -1204.26160061489 239.613094985403 -5.02585887757199 1.38365194008106e-06 OXA1L other 4.3849693988651e-13 0.0201819471980224 1.10067487453523e-05 6.54009567437367 -5.02585887757199 0.294198381176628 39.9946662094848 25.7973288154461 1.55034137431849 0.123125641930853 47.4422188568544 65.0062339591052 0.729810296143288 0.466622033893711 SLC7A7 other 1 1 1 1.55034137431849 0.729810296143288 7.27023652285768e-07 1395.33978064487 349.89768971704 3.98785079653791 0.000104145734200651 -902.227476536915 553.947253943896 -1.62872452225983 0.105483868432211 LARP1 other 0.00670533914503164 1 0.951267136188748 3.98785079653791 -1.62872452225983 0.000128892591994815 168.490630489947 76.0240154018578 2.21628165257145 0.0281778191404053 -279.385570520745 120.173039723116 -2.32486064398856 0.0214204315411405 CNOT8 other 0.931248977162539 1 1 2.21628165257145 -2.32486064398856 0.107895081042513 3.8378956338583 3.55602217221354 1.07926650847323 0.282134803233725 -20.357004236709 13.0073905951875 -1.56503366972318 0.119601302676464 LRGUK other 1 1 1 1.07926650847323 -1.56503366972318 0.000627153018526917 22.8348630625754 12.7031966548575 1.79756825647847 0.0742175162788179 -24.1487323342929 17.715658270172 -1.3631292705026 0.174844428970887 SETD9 other 1 1 1 1.79756825647847 -1.3631292705026 7.10475030537127e-12 141.793483124521 33.7413659084482 4.20236345823269 4.45986030710856e-05 -94.1809399769881 47.3823291220258 -1.98768067594229 0.0486199507842395 MIER3 other 8.7779190022862e-08 1 0.42395432079374 4.20236345823269 -1.98768067594229 5.66210048031438e-10 524.885138385347 75.0580745335878 6.99305360078836 7.29002154318874e-11 396.243292192761 263.23994378259 1.50525519227438 0.134267677112852 NUP205 essential 6.47178084899934e-06 1 9.53534817849088e-07 6.99305360078836 1.50525519227438 3.53727489862243e-08 100.729204072757 17.1671594148569 5.86755220468117 2.61686907036743e-08 46.455569929407 34.6266813663292 1.34161196211486 0.181696818900642 ZKSCAN2 other 0.000363667232327372 1 0.000312846697362426 5.86755220468117 1.34161196211486 2.23588486033968e-07 33.1131899327451 7.50402752187312 4.41272234626341 1.90280494245752e-05 -29.0336400759554 13.7922073099783 -2.10507567232914 0.0368973649021672 C9orf85 other 0.00215919400963002 1 0.187997128314803 4.41272234626341 -2.10507567232914 0.548401686989148 37.5147347740667 34.1597775211172 1.09821367398764 0.273781937101274 37.9255893909626 60.5588129795314 0.626260448727442 0.532047837228866 PIK3AP1 other 1 1 1 1.09821367398764 0.626260448727442 0.0334005421691377 10.7556764309596 4.75679900072545 2.26111644181713 0.0252506200724363 -13.4992265083088 18.0353007800093 -0.748489125463969 0.45538595706251 RBM45 other 1 1 1 2.26111644181713 -0.748489125463969 0.00438264063428057 50.5839457598538 19.2090318216957 2.63334176492548 0.00939168615533077 -86.7354176912806 69.9202780095299 -1.24049017195639 0.216839862069766 TTN other 1 1 1 2.63334176492548 -1.24049017195639 5.38523946632125e-05 1494.68196212998 338.960223804191 4.40960873035482 2.04877019359049e-05 54.3045559781727 1149.95761632874 0.0472230934489053 0.962402719444438 PDIA4 other 0.408529818631769 1 0.201926790280278 4.40960873035482 0.0472230934489053 9.79808833187032e-08 21.0779339853301 4.5177093207 4.66562421109116 6.66637075856064e-06 -9.00876120619394 9.22922983567921 -0.976111914708965 0.330549816382385 KDM8 other 0.000975497674321009 1 0.0687369488915187 4.66562421109116 -0.976111914708965 7.29547209068629e-09 62.2421766914815 14.4870641002677 4.29639685865208 3.07423650488521e-05 -131.610382765663 42.9395401781326 -3.06501611846992 0.00257347835399384 KCTD18 other 7.83971430865148e-05 1 0.297647578402986 4.29639685865208 -3.06501611846992 0.000282409250640837 33.0623503061072 15.8675329793931 2.0836478076992 0.0388550227321789 -123.904040615201 47.0466609791131 -2.63364153877381 0.00931509403723541 FAM126B other 1 1 1 2.0836478076992 -2.63364153877381 0.00744891602878656 6.85415373703341 3.92247812778976 1.74740394050217 0.0825477427461799 -21.110581611845 11.5397363021746 -1.82938163048551 0.0692640465867567 C2CD6 other 1 1 1 1.74740394050217 -1.82938163048551 1.58568713115145e-05 162.300531796041 38.6978852554432 4.19404137266678 4.60926577024569e-05 -88.1137328506949 113.821097883552 -0.774142355759408 0.440033456751968 TMEM237 other 0.128234518296217 1 0.437788062857936 4.19404137266678 -0.774142355759408 0.0403436812118992 371.159451383036 155.389430354622 2.38857591881246 0.0181168848491445 9.51630143283977 460.019128449906 0.0206867515811923 0.983522143507656 FZD7 other 1 1 1 2.38857591881246 0.0206867515811923 0.0684405945284704 25.9413526354262 18.7187317015543 1.38584990954661 0.167905901390026 -106.747177779583 68.2023926997009 -1.56515297417198 0.119711961436691 SPAG17 other 1 1 1 1.38584990954661 -1.56515297417198 0.470623720345542 111.34006306012 108.232518310077 1.02871174762044 0.305282188680281 -217.063777358008 580.642864189221 -0.373833539935266 0.709059568491023 DEPTOR other 1 1 1 1.02871174762044 -0.373833539935266 0.545993073280467 3.00003194179196 4.56228565779208 0.657572139672602 0.511788432475705 -6.85972341770449 14.0433783828028 -0.488466751426762 0.625909624359137 FMN2 other 1 1 1 0.657572139672602 -0.488466751426762 5.64210566500677e-11 269.302715793116 50.5143554248098 5.33121156408637 3.34255055317417e-07 -121.798881393069 75.7997705060797 -1.60685026590285 0.110096553641878 RNF20 essential 6.74795837534809e-07 1 0.0037633776678188 5.33121156408637 -1.60685026590285 0.00071256464079074 165.568652849741 63.1774224344057 2.62069338174794 0.00964283805285279 -146.026655152562 100.877530839279 -1.44756373334727 0.149745748561978 PPARGC1B other 1 1 1 2.62069338174794 -1.44756373334727 0.00498508380778749 84.8859259862395 45.2300252054542 1.87676052800438 0.0624427071884016 -155.742783861907 110.396263333893 -1.41076137143214 0.16033182992234 ELMO1 other 1 1 1 1.87676052800438 -1.41076137143214 0.00892900220594858 379.149087147208 134.003122249958 2.82940487341762 0.00528098092972328 17.4338758481348 214.852220334401 0.0811435684537042 0.935432458346481 SLC26A2 other 1 1 1 2.82940487341762 0.0811435684537042 0.00193429431444982 25.8216238956669 9.58250570323159 2.69466303442521 0.00782842414256562 -12.9582170038627 15.3374736174395 -0.844872977589255 0.39949242236752 LSM11 essential 1 1 1 2.69466303442521 -0.844872977589255 4.82723236434805e-05 38.4542453060229 13.1213006391509 2.93067328945154 0.0039010858932691 -37.4947817605461 20.8121942345479 -1.80157754333781 0.073580917648055 MED7 essential 0.368173012428826 1 1 2.93067328945154 -1.80157754333781 2.11700446772192e-17 461.110787817379 70.7360496940059 6.51875231670526 9.31584447112505e-10 -498.031551946837 162.278008489907 -3.0690021191492 0.0025334667676814 RRAGA other 2.93374479136903e-13 1 1.17687063203723e-05 6.51875231670526 -3.0690021191492 0.918620250988453 0.467796610169491 1.95895910380635 0.238798558510252 0.811575205947936 -0.738983050847459 4.47409698819884 -0.165169206835848 0.869024643326557 SLC24A2 other 1 1 1 0.238798558510252 -0.165169206835848 0.000141797796761856 74.503610930143 17.4166366700025 4.27772665536878 3.29127621592906e-05 2.78377357931823 68.1087345112723 0.0408724901335159 0.967450149085004 PXYLP1 other 1 1 0.317246114453402 4.27772665536878 0.0408724901335159 0.963997728200836 11.8902290076337 45.5101909418705 0.261265197125208 0.794253688149133 36.8708854961832 294.879548700994 0.125037106366336 0.900665005535564 ADCY8 other 1 1 1 0.261265197125208 0.125037106366336 1.32325486788358e-06 84.1810585163661 15.6875371619199 5.36611054032804 2.88136667868764e-07 2.45980410956886 61.4782300907451 0.0400109779663152 0.96813586393098 RASA2 other 0.0119384054180457 1 0.00325594434691703 5.36611054032804 0.0400109779663152 3.31173452954676e-12 138.188033543483 23.2194019109619 5.95140366118752 1.76590509813277e-08 -61.5391164670745 46.8202870153562 -1.31436862928437 0.190702097259019 RMND1 other 4.1363564274039e-08 1 0.000212632632866167 5.95140366118752 -1.31436862928437 0.888462434041184 4.00894164671017 9.19123574614309 0.436170038222819 0.663328189099559 -6.8010124677682 56.6879118539326 -0.119972887434844 0.904662020645369 SLA other 1 1 1 0.436170038222819 -0.119972887434844 1.74169335146639e-15 188.137987787083 21.9687894173277 8.56387597027497 1.16993040616004e-14 -268.787810567301 140.010498040831 -1.91976897681569 0.0567726711050006 TMBIM4 other 2.35546608852315e-11 1 1.62561829935937e-10 8.56387597027497 -1.91976897681569 7.57920524423099e-11 28.2461377831113 6.64686926904032 4.24954014285728 3.70903100916426e-05 -16.5632080730963 13.1053608513563 -1.26384982916225 0.208206129726565 MICU3 other 9.01394879696392e-07 1 0.355288080367844 4.24954014285728 -1.26384982916225 2.7647665544508e-21 54.7394785821006 4.85988581747764 11.2635318272789 9.58762423489284e-22 -4.53453099889623 30.5187806743278 -0.148581656891379 0.882081987289008 GRIP1 other 3.93398633032805e-17 1 1.37879624121994e-17 11.2635318272789 -0.148581656891379 7.57319777117422e-20 161.026199770379 29.7136204890344 5.41927227716342 2.28086966195864e-07 -160.330577879832 56.1199100384175 -2.85692863317272 0.00487308367446559 VPS37A essential 1.06888113342353e-15 1 0.00259494541441035 5.41927227716342 -2.85692863317272 1.9725746384955e-07 93.1146318392851 16.2099762068585 5.7442793654372 5.91766513439475e-08 17.1601631448779 55.2204200724181 0.310757562553371 0.75646779568584 KIF5A other 0.00191655351876223 1 0.000696094949758854 5.7442793654372 0.310757562553371 4.77212560988149e-05 132.062787238889 42.1321851523098 3.13448701417873 0.00206659755733132 -10.8990071416125 80.1813716550072 -0.135929417477506 0.892056935179551 PSD3 other 0.364208626546156 1 1 3.13448701417873 -0.135929417477506 0.000633923787589219 38.6676021068992 22.677630289121 1.70509888440368 0.0901793344426583 -82.0103402124169 33.0513366606701 -2.4813017716771 0.0141579497471554 CARNMT1 other 1 1 1 1.70509888440368 -2.4813017716771 0.00522295707295 116.854510273657 55.8571857082745 2.09202287569505 0.0381211981960723 -171.98959495753 121.558861114344 -1.41486678454275 0.159180140941587 MCU other 1 1 1 2.09202287569505 -1.41486678454275 4.58120577530158e-06 273.192664971076 88.4009349622419 3.09038207670272 0.00236783445572613 -243.871798522152 133.620304510287 -1.82511033346266 0.0698971330911817 ELMSAN1 other 0.0391097537037496 1 1 3.09038207670272 -1.82511033346266 5.40373385963588e-05 115.15852165432 25.9267495672375 4.44168758431025 1.71569085636693e-05 48.9718262120676 55.7731824240727 0.878053288042794 0.381309778819183 CFAP70 other 0.409765138576189 1 0.170265160585854 4.44168758431025 0.878053288042794 0.652159557061317 -1.39301670654498 2.91544520498717 -0.477805826760894 0.63345723740585 -3.89121159506214 4.22624522970006 -0.920725462809527 0.35861540359791 GNA14 other 1 1 1 -0.477805826760894 -0.920725462809527 6.23487465519843e-13 118.125597717308 24.9623510955511 4.73215031970129 4.92124463701068e-06 -124.586651372071 37.8317872139324 -3.29317382410603 0.00122405935637845 FAM161B other 7.96567585948151e-09 1 0.0513138178301104 4.73215031970129 -3.29317382410603 0.103456709529945 182.691207873738 123.2230468471 1.4826058318492 0.140209501275337 -139.040712018795 178.959061627512 -0.776941445458607 0.43837741372442 GNAQ other 1 1 1 1.4826058318492 -0.776941445458607 0.0357630669376189 10.0751562829247 4.36652616922325 2.30736193772016 0.0223753431983489 -4.51081337360403 16.2905664038964 -0.276897270589999 0.782232722536277 MMP16 other 1 1 1 2.30736193772016 -0.276897270589999 0.0329530766746417 45.682180267202 40.2145263619987 1.1359621609362 0.257846445996427 -164.623220222041 93.058035504459 -1.76903820642284 0.0789898887682727 ADK other 1 1 1 1.1359621609362 -1.76903820642284 0.0726555278676841 118.910480139761 113.620022190129 1.04656272589684 0.296984800655016 -401.073926356811 276.538255224921 -1.45033795064122 0.14905213074147 KCNMA1 other 1 1 1 1.04656272589684 -1.45033795064122 0.436806237972205 -7.77538914042103 8.42689753704849 -0.922687039475307 0.357613657692584 -15.5800037454421 12.6585668114875 -1.23078733773427 0.220278922958663 BATF other 1 1 1 -0.922687039475307 -1.23078733773427 2.98873681154656e-16 176.846511663708 27.6558885254413 6.39453371751273 1.85278693844448e-09 -259.13923069818 73.8922489100039 -3.50698800646595 0.000595087987822641 DCK other 4.08709758978992e-12 1 2.31876285346327e-05 6.39453371751273 -3.50698800646595 1.15710862505396e-10 76.6912005608659 11.1236806423358 6.89440869679284 1.35591057626695e-10 28.4041551957047 29.6471871811774 0.958072515349387 0.339547605267309 ADAMTS3 other 1.36642957532622e-06 1 1.75956515482162e-06 6.89440869679284 0.958072515349387 0.00461148702560697 28.7727602185421 9.57773790064622 3.00412900384346 0.00311582062557018 -18.211533943505 32.3609695225243 -0.562762309418113 0.574425847240967 ALX3 other 1 1 1 3.00412900384346 -0.562762309418113 1.00574067371122e-07 161.42780729927 31.1062718086084 5.18955817953716 6.64883849855144e-07 -185.617838248175 125.321716604746 -1.48113067133926 0.140641730503555 DPY19L4 other 0.00100071197034266 1 0.00734563677319963 5.18955817953716 -1.48113067133926 8.78800546867891e-09 93.3727356463003 16.4860767811043 5.66373291147839 7.19812529738876e-08 -99.1603798412211 68.7444080107504 -1.44245012373536 0.151232856108022 NDUFAF6 other 9.40316585148643e-05 1 0.000842252641047459 5.66373291147839 -1.44245012373536 0.00495487910179379 9.04697967738302 46.0061174924677 0.196647319323658 0.844361142881461 -460.387645495714 148.909177983292 -3.09173451717913 0.00236018527604742 DRAM2 other 1 1 1 0.196647319323658 -3.09173451717913 0.0045429418106937 16.7412725194579 6.83889517370875 2.44794986532584 0.015505422610275 -43.1761911500571 28.5998077981901 -1.50966717870004 0.133204312390637 C8orf37 other 1 1 1 2.44794986532584 -1.50966717870004 0.200156748377144 -5.91672482606704 8.16256339329372 -0.72486111788463 0.469644332108143 -26.0170061721664 14.4363100049375 -1.80219226126815 0.073483711958791 CFAP161 other 1 1 1 -0.72486111788463 -1.80219226126815 0.519309927773515 14.1905804754082 13.0162655471185 1.09021903587006 0.277341968577892 1.47303445480994 21.7671899149677 0.0676722379215814 0.94613548515335 ADAMTSL3 other 1 1 1 1.09021903587006 0.0676722379215814 3.23632615375883e-05 42.8750676443015 15.3665362121148 2.79015824076862 0.00594811634579191 -67.0069873705231 26.8886093313349 -2.49202130704602 0.0137823251996359 WHAMM other 0.252530529777801 1 1 2.79015824076862 -2.49202130704602 0.366213251272803 53.0668865954413 37.3775497735195 1.41975295108929 0.157700744643351 48.8761740463861 61.1728380853517 0.798984902060476 0.425529705556287 CXCL13 other 1 1 1 1.41975295108929 0.798984902060476 0.000286202225990208 22.3930838617733 13.751163231446 1.62845015253437 0.105677756264676 -73.5533869823945 26.4545554591423 -2.78036752860935 0.0061772490375358 N6AMT1 other 1 1 1 1.62845015253437 -2.78036752860935 0.0104935715614716 52.5366295359804 33.5565389645349 1.56561526179756 0.119696290828452 -110.315588054397 65.048554336369 -1.69589607609034 0.0921282116795349 RWDD2B other 1 1 1 1.56561526179756 -1.69589607609034 1.38625000723463e-05 143.744057951206 35.20817967919 4.08268928586976 7.45069725772366e-05 -48.1620515273696 68.2502206609251 -0.705668803133169 0.481566669821662 USP16 other 0.112820645334732 1 0.690903156708715 4.08268928586976 -0.705668803133169 5.47016523398447e-08 679.690323241988 174.511960823249 3.8948065223472 0.000151642578153796 -875.412150618464 338.287294108454 -2.58777721145451 0.0106779973299991 CCT8 essential 0.000555002964640064 1 1 3.8948065223472 -2.58777721145451 0.512877008482633 -2.17975924868987 5.32339192618663 -0.409468113359694 0.682821960236154 -12.2133814144139 10.583392424269 -1.15401384781001 0.250460688953524 MAP3K7CL other 1 1 1 -0.409468113359694 -1.15401384781001 0.000442269435201076 187.126640219713 60.5944664674322 3.08818034267681 0.00241980467392723 -127.081964667161 129.694029270808 -0.979859792942412 0.328810160325442 TIAM1 other 1 1 1 3.08818034267681 -0.979859792942412 1.32677689652428e-09 304.246100981975 58.3855501784036 5.2109828553866 6.20180334373244e-07 -194.219826117867 114.505740693117 -1.69615798249267 0.0919583875610781 SCAF4 other 1.48851100021059e-05 1 0.00686973756385243 5.2109828553866 -1.69615798249267 9.38159514660592e-08 85.5733820391803 28.2768555078301 3.02626938187962 0.00289985587408833 -118.594760888774 42.1081701541253 -2.81643112143535 0.00548801177096094 CDK20 other 0.000935438852068076 1 1 3.02626938187962 -2.81643112143535 1.31756304739479e-05 24.3375862493256 9.5191077489862 2.55670876841557 0.0115274947868011 -31.7849043567149 16.4956305743851 -1.92686810082128 0.0558254608618134 PCGF6 other 0.107539495928363 1 1 2.55670876841557 -1.92686810082128 0.0362416859690103 132.385926244744 51.6094703415243 2.56514793445241 0.0113288768275462 62.76958222382 88.7089738319899 0.707589993574971 0.480335667605781 ANKRD9 other 1 1 1 2.56514793445241 0.707589993574971 9.2889353805807e-05 8.96134968454036 12.4507066645774 0.719746270308949 0.472765097187826 -68.0765646372805 21.3791659354187 -3.18424791888156 0.00175451988488445 SFR1 other 0.684222980133574 1 1 0.719746270308949 -3.18424791888156 4.51109918294713e-06 121.40105939181 50.4955586231532 2.40419281818076 0.0174038826606987 -201.896426112038 89.1836759631234 -2.26382714024391 0.0249904302479617 SFXN2 other 0.0385383203199174 1 1 2.40419281818076 -2.26382714024391 1.05542844054181e-05 585.971707150593 175.814463640652 3.33289818719501 0.00108582114061866 -685.633338458238 346.006529933884 -1.98156184679304 0.0493808011311991 C14orf2 other 0.0870517377758888 1 1 3.33289818719501 -1.98156184679304 0.192080502268574 -11.4915734859541 15.4976690284806 -0.741503348976908 0.459503122804571 -53.2124572182376 30.0123846110251 -1.77301663656176 0.0781774056138249 FUT6 other 1 1 1 -0.741503348976908 -1.77301663656176 0.547611178979756 3.14803346984294 46.1177171254467 0.0682608261219835 0.945670142833732 93.389901433435 91.22103099656 1.02377599127285 0.307611553152892 TDRD9 other 1 1 1 0.0682608261219835 1.02377599127285 0.0731031172847819 218.125043377675 96.0660900360887 2.27057272025678 0.0245685023221933 195.502069275753 160.230449097141 1.22013057054611 0.224292688003479 FGF18 other 1 1 1 2.27057272025678 1.22013057054611 0.149985010606089 268.438944069845 240.074260364314 1.11814962446406 0.265290658740205 -307.579825330862 359.857138688276 -0.854727591210304 0.394065046743146 PCDH1 other 1 1 1 1.11814962446406 -0.854727591210304 0.406755962782374 -8.86254549711597 43.0725562456762 -0.20575852165741 0.83724610197345 -81.7631382899472 64.2317385729724 -1.27293982860292 0.204921115161065 SH3RF2 other 1 1 1 -0.20575852165741 -1.27293982860292 0.0707561726191722 3.90697243309476 1.72125549279556 2.2698387598167 0.0246141064842359 8.28952258659589 7.49472978113345 1.106046892773 0.270442312041478 GDF6 other 1 1 1 2.2698387598167 1.106046892773 0.00326455697180395 490.628138408743 205.452400262598 2.38803799703313 0.0181583747209744 -1534.48144422189 894.585509994553 -1.71529879153893 0.0883148937824755 UQCRB essential 1 1 1 2.38803799703313 -1.71529879153893 8.92065396097418e-09 127.175108852426 21.4559032818092 5.92727824981613 1.9687773618714e-08 -78.3188053587496 93.4237816409943 -0.838317652990225 0.403160080534182 MTERF3 other 9.54063941126189e-05 1 0.000236666726670561 5.92727824981613 -0.838317652990225 5.05527798078648e-07 402.373130512591 77.1235185096885 5.21725588105843 5.85868202485032e-07 -194.125011062056 346.788810966234 -0.559778761376927 0.576454338671187 PTDSS1 other 0.00472921255102575 1 0.00649669249735652 5.21725588105843 -0.559778761376927 0.337080339146654 -25.1617391304345 56.9195640482103 -0.442057832859062 0.659055680578113 -126.432391304348 86.8649897068837 -1.45550459087119 0.147526269329122 PPP2R2B other 1 1 1 -0.442057832859062 -1.45550459087119 0.000213450779756412 6292.25285171103 1705.11827710175 3.69021488785294 0.000312250583448496 -6590.4340450424 7549.84689247433 -0.872922873656118 0.384091131334189 RPL30 essential 1 1 1 3.69021488785294 -0.872922873656118 4.90216679006664e-12 203.808763636364 31.8088830179184 6.40729080369013 1.68809087996016e-09 -117.525003636364 68.4384431341722 -1.71723666194391 0.0879332642466921 SUPV3L1 essential 6.08702050322574e-08 1 2.11484025441409e-05 6.40729080369013 -1.71723666194391 9.5322107363774e-07 16780.7339215686 5983.75575362933 2.80438149758879 0.00571365999046792 -27189.5639549438 11229.1413546391 -2.42133953935052 0.0166653788963184 EEF1A1 essential 0.00871434705519622 1 1 2.80438149758879 -2.42133953935052 0.130323442095033 4.32679263565891 2.26735381950882 1.90830059183098 0.058288597733093 -0.406976744186061 9.77051749639486 -0.0416535505244454 0.96683102357439 FBXO43 other 1 1 1 1.90830059183098 -0.0416535505244454 0.197661747840434 69.0944690657685 45.111202125501 1.53164770190662 0.127647842671911 -29.0821095550436 98.240519895593 -0.296029678852995 0.767603657220747 HKDC1 other 1 1 1 1.53164770190662 -0.296029678852995 0.000368447044336331 345.188604488079 117.368456493127 2.94106793939387 0.00376924684599529 -374.322496493689 256.051681709981 -1.46190212067292 0.145779551567245 HK1 other 1 1 1 2.94106793939387 -1.46190212067292 8.52139435511177e-08 149.446429721967 37.9264781051229 3.94042466341689 0.00012242434600018 -210.842522542075 82.0945515746229 -2.56828886324352 0.011158710295409 TYSND1 other 0.000853076788890239 1 1 3.94042466341689 -2.56828886324352 0.0121727899512953 182.925541968285 113.968328923558 1.60505592822176 0.110570905523663 -275.672779678316 219.214529530612 -1.25754793839895 0.210496693623399 CD109 other 1 1 1 1.60505592822176 -1.25754793839895 0.0803514168014769 270.525356652729 290.771453915622 0.93037109733348 0.353694046087003 -1782.41584272173 1049.934526216 -1.69764475614077 0.0916765478971976 UBE2L6 other 1 1 1 0.93037109733348 -1.69764475614077 0.000639495345497892 324.698464877286 126.564364224751 2.56548094612707 0.0112975350012425 -954.690645645166 457.005988719595 -2.08901123663597 0.0384185065012441 ZDHHC5 other 1 1 1 2.56548094612707 -2.08901123663597 3.05969574880915e-06 100.489420100213 24.3835442406717 4.12119826011993 6.25223722966235e-05 -168.11661187885 88.045523812752 -1.90942826618178 0.0581418880597102 MED19 essential 0.0266009948401467 1 0.585084359951803 4.12119826011993 -1.90942826618178 2.62772011424341e-13 451.073546847888 66.6503662769594 6.76775795910099 2.62034571528645e-10 -303.991973684211 198.316138846281 -1.53286553203742 0.127374152510914 ZFAND3 other 3.39264943949966e-09 1 3.36766831328615e-06 6.76775795910099 -1.53286553203742 0.00226595978279519 323.696155180831 141.678321084729 2.28472608019719 0.0237311714701397 -411.904011857359 247.018059642375 -1.66750565709123 0.0975003245665356 NPTN other 1 1 1 2.28472608019719 -1.66750565709123 1.11530712225079e-08 507.684332706197 81.6713897221919 6.21618334686239 5.0583785642429e-09 151.369348182313 191.289882930355 0.791308697896081 0.430047520881233 KAT6B other 0.000118545994024037 1 6.22989903972155e-05 6.21618334686239 0.791308697896081 0.00250308423034829 67.4720989359826 20.5170840328503 3.2885813026818 0.00126000486442648 3.51292545999641 48.6166492368501 0.0722576630668678 0.942495076719355 SAMD8 other 1 1 1 3.2885813026818 0.0722576630668678 0.000379919458071975 164.274807719397 50.8836452370641 3.22844023760581 0.00156022063431804 -240.928278630793 173.80647781284 -1.38618699177732 0.167958292252613 RAB11FIP1 other 1 1 1 3.22844023760581 -1.38618699177732 0.587675762260651 -24.3708431211615 26.7735512741517 -0.910258145122873 0.364127580516648 -73.4726686100813 100.851264283689 -0.728525012868522 0.467413181114465 GLYATL2 other 1 1 1 -0.910258145122873 -0.728525012868522 0.0014024485901874 75.0260778092604 61.5356850931955 1.21922877263223 0.224633697604632 -459.431728849602 178.209735991963 -2.57803944488376 0.0108799037880447 MAPK13 other 1 1 1 1.21922877263223 -2.57803944488376 2.18699990212754e-29 234.473349633252 16.7395754083016 14.0071264601472 2.36992791059711e-28 -17.7335813755715 58.3089623786335 -0.304131314503887 0.761482669028311 BAG4 other 3.16765065824152e-25 1 3.43544749920157e-24 14.0071264601472 -0.304131314503887 0.128192885410864 16.9988194495684 8.75459462686939 1.94170263433969 0.0540103610308295 0.276861211539495 29.020333909947 0.0095402489991543 0.992400526342683 MS4A1 other 1 1 1 1.94170263433969 0.0095402489991543 2.23924208184426e-07 89.0046192609181 16.1642703577592 5.50625653314406 1.53908247445988e-07 -33.6714089382063 90.8447890803323 -0.370647664869708 0.711419413463892 TBC1D31 other 0.00216221215422882 1 0.00177102220336099 5.50625653314406 -0.370647664869708 2.81885006662408e-06 65.5184217294925 12.6905588962076 5.16276881620018 7.51125503476416e-07 22.1955834971147 73.7461681503175 0.300972702091765 0.763846618286228 WDYHV1 other 0.0246057422315616 1 0.00826613616575795 5.16276881620018 0.300972702091765 6.10996863569895e-05 223.656249746965 54.4478295751827 4.10771653327588 6.54781509476155e-05 -256.519566643185 313.996258779245 -0.816951028781307 0.415252039898666 ATAD2 other 0.460141737954488 1 0.611368470238256 4.10771653327588 -0.816951028781307 0.0162177208715618 342.028253523838 132.696189386962 2.57752882809944 0.0109016337928273 -486.84977921412 771.111467625088 -0.631361093245763 0.528752755568674 FBXO32 other 1 1 1 2.57752882809944 -0.631361093245763 2.03831337854249e-17 155.484164368605 15.8303421297331 9.82190802285748 7.25431875038492e-18 246.054604056721 147.037582531787 1.67341301332622 0.096344159371948 NSMCE2 essential 2.82489851132204e-13 1 1.02989563299215e-13 9.82190802285748 1.67341301332622 5.78009614317231e-08 108.307662223016 18.6999802405013 5.79185971482678 3.75774782917975e-08 34.6329016325664 39.8880314140773 0.868252967238282 0.38659819436056 ZNF689 other 0.00058569714218765 1 0.000446119822280219 5.79185971482678 0.868252967238282 1.11925936193665e-07 141.98277480417 47.3946192946723 2.99575725930834 0.00318840298830207 -331.999078119588 101.095190421091 -3.28402445988493 0.00126509715775109 PRR14 other 0.00110896217580683 1 1 2.99575725930834 -3.28402445988493 2.94457461012251e-07 538.474201316331 140.41488964989 3.83487963889699 0.000182330680777594 -642.121389301718 299.5122699236 -2.14389009660777 0.033601173266948 FBRS other 0.00280997684282422 1 1 3.83487963889699 -2.14389009660777 0.00295851554072279 27.6115112540192 10.6199228994241 2.59997285437133 0.0102364365076996 -49.03848627257 33.5017530569043 -1.46375881253963 0.145311354402446 FRRS1 other 1 1 1 2.59997285437133 -1.46375881253963 5.48350051513167e-06 30.0994206121282 52.6685542648299 0.571487503924661 0.568496995326659 -483.416932987675 112.344768284806 -4.30297681296704 2.97335461991208e-05 PHKG2 other 0.046434282362135 0.429292940022906 1 0.571487503924661 -4.30297681296704 1.35155967101943e-08 142.805922542829 50.0905561846792 2.85095501867291 0.00496078761407483 -701.179645534981 154.01705998565 -4.5526102472045 1.07413926004219e-05 MFSD14A other 0.000143022044387276 0.155943537772925 1 2.85095501867291 -4.5526102472045 5.03038330233279e-09 70.4887900668435 13.9335558080945 5.05892329550898 1.19311818384074e-06 -104.431751153352 42.8425129239245 -2.43757296260356 0.0159322856472317 SASS6 essential 5.46098411301247e-05 1 0.0129787396038196 5.05892329550898 -2.43757296260356 3.30559189644373e-07 375.646284443234 76.0450536329824 4.93978590976111 2.02876828162125e-06 57.5798663125884 179.188526009462 0.321336793124511 0.748393724061901 MALSU1 other 0.0031429567751387 1 0.0217605685886695 4.93978590976111 0.321336793124511 4.1654092488823e-10 172.221241043809 24.3544843515238 7.07143861303039 5.42918941975959e-11 39.906494803193 104.8798735575 0.3804971673742 0.70411468545011 VPS8 other 4.79605220916308e-06 1 7.12363943766655e-07 7.07143861303039 0.3804971673742 5.86427713569612e-11 60.6110882610394 13.917576363396 4.35500310387732 2.4349179547841e-05 -66.6222883116608 20.8938816167138 -3.18860274667045 0.00173617931557516 GALK2 other 7.00781117715686e-07 1 0.237940182541502 4.35500310387732 -3.18860274667045 0.386311008372979 37.2742827660871 75.2467663941137 0.495360592252679 0.621038221806568 -159.523673793897 170.813937223528 -0.933903148577057 0.351787951185042 B3GNT7 other 1 1 1 0.495360592252679 -0.933903148577057 0.0031730702948348 25.4733643448994 17.5169665755368 1.45421093515552 0.147909767929529 -92.0365038186718 45.068304148073 -2.04215591330625 0.0428310234145993 MPV17L other 1 1 1 1.45421093515552 -2.04215591330625 3.68269890561512e-06 263.794887703189 57.9565206053457 4.55159980184969 1.07869152949915e-05 20.7581585804687 82.6867582422127 0.251045742048107 0.802115584774744 BUB1B other 0.031766960759836 1 0.109239091192379 4.55159980184969 0.251045742048107 0.0885371174087482 48.0470748561639 34.9088260672357 1.37635894039013 0.170695630237451 -74.3452178028225 78.5108109343006 -0.946942426375344 0.345142055520096 PDE6D other 1 1 1 1.37635894039013 -0.946942426375344 1.10098717314212e-10 161.892407622706 30.0614293540353 5.38538622751731 2.65279009575742e-07 -140.947745539099 62.227583018327 -2.26503647904158 0.0249051344659972 BRPF1 other 1.30180723352324e-06 1 0.00300561117849316 5.38538622751731 -2.26503647904158 1.68419331279708e-06 136.036265293619 30.4520263647771 4.46723195573508 1.52002571625362e-05 -55.4450064052185 62.623717256472 -0.88536753859798 0.377329880366046 RPUSD3 other 0.0150533198297803 1 0.151622565196299 4.46723195573508 -0.88536753859798 0.400259365925956 -1802.66290103182 1478.52886413609 -1.21922739877325 0.224646539724613 -4724.07229355363 5873.42457108954 -0.804313094749985 0.42247235611831 SST other 1 1 1 -1.21922739877325 -0.804313094749985 3.53740586733627e-08 205.452154926599 52.6570502092646 3.9017026990709 0.000141034162112536 -244.124768520002 108.171018217669 -2.25684081136001 0.0253889238817257 TATDN2 other 0.000363667232327372 1 1 3.9017026990709 -2.25684081136001 0.0748329466317815 6.30858829844338 2.92608527848628 2.15598237851322 0.0325981957540053 2.13424584004295 5.68549820044758 0.375384137818376 0.707878260083442 GHRL other 1 1 1 2.15598237851322 0.375384137818376 0.000228126377233753 116.104830917875 93.2284213528171 1.24538020952305 0.214835782136775 -522.226570048309 181.146470927948 -2.88289673750271 0.00448950437991538 SEC13 essential 1 1 1 1.24538020952305 -2.88289673750271 0.000215509743353032 7.95673835370302 6.51896948646998 1.22055155653315 0.224097574181 -44.3942908798012 14.3533231918699 -3.09296253462384 0.00234853503835246 EXOG other 1 1 1 1.22055155653315 -3.09296253462384 0.00487099144886867 65.7215498909855 21.300413270906 3.08545890894774 0.00240506240200128 23.1547603025492 54.7039264817749 0.423274192397567 0.672678182713609 NTAN1 other 1 1 1 3.08545890894774 0.423274192397567 5.24433119776466e-06 189.191074865519 42.0638141426894 4.49771564280269 1.36150614765163e-05 -114.904567438188 130.580405321459 -0.879952602041015 0.380283277963515 ZFYVE9 other 0.0444929058818354 1 0.136341225625834 4.49771564280269 -0.879952602041015 0.00319301044242124 134.217326813365 45.2333260148395 2.96722214876114 0.00347563073907525 -5.95170334148382 87.9979859693363 -0.067634540449116 0.946162616402971 ATP2B2 other 1 1 1 2.96722214876114 -0.067634540449116 0.605764635343492 -0.241450692746588 1.83328578583875 -0.131703793599273 0.895387212117726 2.84933985330066 3.56651767785319 0.798913705375427 0.425547385966102 SLC6A1 other 1 1 1 -0.131703793599273 0.798913705375427 0.00025266590363009 378.494301674441 116.886873949109 3.23812493983911 0.00146823496611941 -117.099870773798 237.222099847478 -0.493629686479835 0.622257568600203 SMG1 essential 1 1 1 3.23812493983911 -0.493629686479835 4.14131273306371e-11 64.959901971008 44.4118651657339 1.46266998083944 0.145608853061828 -264.344057426913 63.0189815070335 -4.19467359048655 4.61233920435089e-05 FCHO2 other 4.9791002989625e-07 0.664038475250398 1 1.46266998083944 -4.19467359048655 2.86572879612578e-07 23.5345333875042 130.630610568167 0.180160938428923 0.857266190963174 -974.584115298622 249.532815162763 -3.90563507514203 0.000140990835032243 RBPMS other 0.00273877701045741 1 1 0.180160938428923 -3.90563507514203 0.00307629550969102 0.298988424236143 7.08049260709539 0.0422270653791129 0.966372743141501 -24.4581812493481 10.046987015792 -2.43437970118848 0.0160681217931937 TMEM171 other 1 1 1 0.0422270653791129 -2.43437970118848 0.0104159121170629 13.6441852900916 32.6950038884319 0.417317133120734 0.677027655812707 313.361256047813 103.920939374668 3.01538128825074 0.00300287249740796 C8A other 1 1 1 0.417317133120734 3.01538128825074 0.296328345795999 -18.5200751476114 15.7400552129636 -1.17662072318261 0.241116538318829 -45.219216317767 30.5835432228226 -1.47854733469936 0.141252157891134 TIMP4 other 1 1 1 -1.17662072318261 -1.47854733469936 0.898625352764597 2.86049382716049 6.23779085136873 0.458574821650653 0.647169674384588 2.10246913580245 12.120271723103 0.173467161779454 0.862506275950547 SYN2 other 1 1 1 0.458574821650653 0.173467161779454 3.63229588138038e-05 63.9582016157359 15.6716162313516 4.0811490449712 7.23711305675228e-05 37.5014437617178 30.4700423922725 1.23076441046332 0.220324690903411 NRG1 other 0.281430284889352 1 0.671965947319449 4.0811490449712 1.23076441046332 6.1519317556989e-09 143.087017257578 34.3719903933004 4.16289588180112 5.26113343682231e-05 -364.533897047915 106.689087810568 -3.41678708224749 0.000814374291268491 CPT2 other 6.64285590980368e-05 1 0.496650996436026 4.16289588180112 -3.41678708224749 4.8905286049384e-08 127.787630291878 51.5197103980742 2.48036390935642 0.0142225219037845 -364.144610365241 114.915768558561 -3.16879584875832 0.00185320078587961 NECAP2 other 0.000497709096124581 1 1 2.48036390935642 -3.16879584875832 0.00193498102325658 62.5777582273852 73.7214241052211 0.848840876134856 0.397313515577998 -670.322866952656 224.088675390048 -2.99132861482579 0.00324495141000861 LRP8 other 1 1 1 0.848840876134856 -2.99132861482579 0.00144947228476579 84.6845298587832 26.4969549146248 3.19600988610364 0.00169084494202656 -46.6996223095242 77.9151222194232 -0.599365321894888 0.549810053466211 PAXIP1 other 1 1 1 3.19600988610364 -0.599365321894888 0.525799480420888 49.9514713867903 49.6368211084333 1.00633904974836 0.315841389204461 -34.8036563175796 153.782285188214 -0.226317721023481 0.821256386250606 STEAP2 other 1 1 1 1.00633904974836 -0.226317721023481 1.35662180284533e-09 841.58681498949 159.957515177345 5.26131463130334 4.85596849295011e-07 -1091.9121341057 485.843534030144 -2.24745634679571 0.0260696698132803 SSBP3 essential 1.52145135189104e-05 1 0.00541731845073515 5.26131463130334 -2.24745634679571 3.51085726626279e-07 144.741529350875 34.0234010715361 4.25417579643339 3.65331195413631e-05 -262.391153211925 105.34442044527 -2.49079307762907 0.0138208975061869 CLDN12 other 0.00333075028850351 1 0.350279550162589 4.25417579643339 -2.49079307762907 0.526893045250078 484.261431675708 451.266788436032 1.07311560275469 0.284931212199776 -7.92851782950439 1082.41303008727 -0.00732485438471222 0.994165332360134 MMP14 other 1 1 1 1.07311560275469 -0.00732485438471222 0.337114065235875 -91.2743038065766 61.9248432022452 -1.47395292562109 0.142535478982591 -108.505342879758 190.026213374927 -0.57100197363652 0.568830616371825 FZD1 other 1 1 1 -1.47395292562109 -0.57100197363652 1.60215410831749e-08 180.622296808032 35.5273391267247 5.08403672348664 1.07925560053516e-06 -216.675362545746 111.378962953939 -1.94538857966699 0.053585742554968 GATAD1 other 0.000168770913770164 1 0.0117746786018386 5.08403672348664 -1.94538857966699 0.0655506796339913 19.0075184201287 126.347858577863 0.150437994233318 0.880614659686814 -354.874893489049 186.959747252911 -1.8981352868914 0.0595371103175824 SUSD3 other 1 1 1 0.150437994233318 -1.8981352868914 2.75209679860016e-10 179.998235526888 37.6812778854889 4.77686123262304 4.33929606825274e-06 -307.372913607849 85.0393950749616 -3.61447671795998 0.000415238736185885 ZFHX2-AS1 other 3.19573480253451e-06 1 0.0454584656110157 4.77686123262304 -3.61447671795998 1.22374706395308e-15 512.760367000136 58.7079310831616 8.73409022494414 4.31630420564576e-15 352.013451118217 94.9055235098616 3.70909340257355 0.000291676971430149 CLEC18A other 1.65915626930758e-11 1 6.02383414939922e-11 8.73409022494414 3.70909340257355 0.631561407150353 -10.3168560237785 16.6682530528206 -0.618952447571142 0.536856302347062 -42.4273405742752 44.9599713871014 -0.943669207637601 0.346807307910211 C1orf158 other 1 1 1 -0.618952447571142 -0.943669207637601 3.37086221023222e-15 570.969507889789 66.7171732164328 8.55805904781884 1.21035124328069e-14 388.390415632017 107.853029980471 3.60110806068538 0.000429277421041136 CLEC18C other 4.53313550032028e-11 1 1.68154098228987e-10 8.55805904781884 3.60110806068538 8.10665087370586e-14 190.735668344519 32.6728935164276 5.83773421379467 3.09179360841553e-08 -26.3253013919962 52.5413442933274 -0.50103973824932 0.61706796317966 DDX19B other 1.06026886777199e-09 1 0.000368356290506626 5.83773421379467 -0.50103973824932 9.29756993292843e-10 420.186451342282 72.6227860696503 5.78587622539425 3.98359169079576e-08 149.929110738256 116.784845043114 1.2838062223134 0.201163336513216 ST3GAL2 other 1.05109028091756e-05 1 0.000472294630860746 5.78587622539425 1.2838062223134 1.34579079688974e-15 156.833389971624 31.3316588301594 5.00558846315085 1.56167051178128e-06 -106.346218544509 51.0076100364907 -2.08490886886152 0.0387950623560353 FUK other 1.82327737162623e-11 1 0.0168613565157025 5.00558846315085 -2.08490886886152 0.00067271631998229 93.4351969121284 26.2154862284096 3.56412221761019 0.000487321652647595 54.1136240275016 41.7218219084843 1.29701009093511 0.196580200096532 IL34 other 1 1 1 3.56412221761019 1.29701009093511 7.24424342576106e-05 70.8164988951631 30.865577423593 2.29435198711146 0.0232162645761457 -157.371415779668 64.0263027795386 -2.45791821404313 0.0151613022240852 DHRS1 other 0.541434753641382 1 1 2.29435198711146 -2.45791821404313 6.69430107719212e-06 33.6941827842387 10.9006741967346 3.09101824126915 0.00238394942498418 -47.3561487100718 24.5738042923207 -1.9270987978394 0.0558831527073107 CACNA1D other 0.0562120461451822 1 1 3.09101824126915 -1.9270987978394 0.000487652884874998 51.2696779964223 12.9574783091385 3.95676355948544 0.000118847180683335 40.8775478397572 22.3594179724681 1.82820267907202 0.0695886902253379 KIT other 1 1 1 3.95676355948544 1.82820267907202 0.000708786308899839 124.560993363306 55.4215261545369 2.24752008842161 0.0260955135273344 -58.7042860201241 88.9821735441206 -0.659730861609223 0.510458854595351 HYDIN other 1 1 1 2.24752008842161 -0.659730861609223 4.67626407147054e-17 98.2214177799659 12.519887503014 7.84523165693941 6.92877899947167e-13 -0.817710366836928 21.7457389487119 -0.0376032458021099 0.970053038746607 AASDH other 6.45417967144363e-13 1 9.43353260778067e-09 7.84523165693941 -0.0376032458021099 1.98303234439989e-18 48.0867496830958 7.18995310663951 6.68804774800136 3.93558289161319e-10 -12.273074341958 11.446034683589 -1.07225556109443 0.28528269275036 ZNF19 other 2.77525376598764e-14 1 5.02692002745753e-06 6.68804774800136 -1.07225556109443 0.0859279088992047 22.8282670354702 18.1470996148193 1.25795678207597 0.21031143336546 -38.083584890964 40.347126950306 -0.94389830874129 0.346700108579923 CACNA2D3 other 1 1 1 1.25795678207597 -0.94389830874129 4.39193717592376e-12 252.007586856426 37.9498004969067 6.64055103206582 5.21716215219312e-10 -60.4272577438257 60.9241053042731 -0.99184481154108 0.322849526641325 RNF111 other 5.46532662171952e-08 1 6.64457771703316e-06 6.64055103206582 -0.99184481154108 0.0283696726014963 212.28762034324 80.5104311402021 2.63677162495328 0.00923915380021853 79.1007874633739 129.250376040262 0.611996575071733 0.541454382484801 CCNB2 other 1 1 1 2.63677162495328 0.611996575071733 0.425441643518757 4.45890075093727 9.91934594060146 0.449515600891212 0.653700088978852 -14.6629665871385 15.8742904082357 -0.923692726418259 0.357110317965682 FAM81A other 1 1 1 0.449515600891212 -0.923692726418259 0.00360585810135509 137.159976939138 50.8721986685638 2.69616766188435 0.00781063961343753 -61.2251683932638 81.5936012175541 -0.750367277331201 0.454201171203361 MYO1E other 1 1 1 2.69616766188435 -0.750367277331201 8.37503354084084e-15 353.579864772657 55.0856754152053 6.41872614082641 1.59091441075724e-09 -290.330027603747 125.094433058524 -2.32088687326253 0.0215961763542507 APPL1 other 1.11907198172715e-10 1 1.9942112138842e-05 6.41872614082641 -2.32088687326253 0.870223080650104 4.86679620034539 55.9465844219461 0.0869900504316809 0.930790979369975 45.1947994626751 89.3318068054591 0.505920579453825 0.613626566504943 AFAP1L1 other 1 1 1 0.0869900504316809 0.505920579453825 3.50914192707947e-05 101.706618921038 44.3987535721075 2.290753922987 0.0233522527520912 -234.424206224094 87.9571418327086 -2.66520945700987 0.00852537941868288 DSCR3 other 0.272695419153346 1 1 2.290753922987 -2.66520945700987 1.41930016748493e-08 343.641734230782 74.6885430383504 4.60099662212359 8.80464292438903e-06 -289.531275219036 147.96340538329 -1.95677623442785 0.0522062159542508 DYRK1A other 0.000150005834701482 1 0.0898689903292389 4.60099662212359 -1.95677623442785 0.821222156668006 -0.123853424053145 9.67638593729182 -0.0127995539714705 0.989804496776641 -10.8953742191673 18.9847020007156 -0.573902830750601 0.566881802424437 KCNJ15 other 1 1 1 -0.0127995539714705 -0.573902830750601 0.329779762034156 -25.2228537259364 17.0487221944137 -1.47945713692262 0.141087716631692 -27.5216194877272 33.4489459651003 -0.822794820394115 0.411913630250598 ERG og 1 1 1 -1.47945713692262 -0.822794820394115 0.170288169652035 -1.71624927403628 82.5152325144817 -0.0207991812146329 0.983433309629332 -278.782665446461 161.994165624749 -1.7209426300713 0.0873094823420116 ETS2 other 1 1 1 -0.0207991812146329 -1.7209426300713 0.0204185695944213 225.85875 91.1442067933195 2.4780373645926 0.0143501420491137 392.356875000001 161.149256543732 2.43474207337422 0.016108557271865 TSPAN18 other 1 1 1 2.4780373645926 2.43474207337422 0.215892650492032 8.03286308596924 9.56951483017066 0.839422188953961 0.402559446823909 -18.9785599739698 18.0826395662116 -1.04954588651052 0.295603834131122 LCA5L other 1 1 1 0.839422188953961 -1.04954588651052 0.0314648530089998 644.75491726823 795.951450523487 0.810043020644266 0.419165380525803 -2994.5669458188 1524.37609647735 -1.96445414798808 0.0512773423749462 MX1 other 1 1 1 0.810043020644266 -1.96445414798808 0.0751677234434167 14.2885781262631 29.0663887582865 0.49158422276278 0.623794277175398 436.141675423706 190.094564190208 2.29434059454379 0.0232804257193919 CREB3L1 other 1 1 1 0.49158422276278 2.29434059454379 0.000458857344877771 117.735379998378 40.0243494885455 2.94159384232022 0.00376989690211727 -96.8561116067808 76.6531194801733 -1.26356386098328 0.208296075245403 C2CD2 other 1 1 1 2.94159384232022 -1.26356386098328 2.96936158569648e-05 444.5316952351 94.4924159673621 4.70441665274642 5.9431794384756e-06 329.578204120145 418.962656411885 0.786652936905513 0.432786783592954 SLC38A10 other 0.232916722782032 1 0.0615594526237303 4.70441665274642 0.786652936905513 6.35629271440838e-12 40.6723480939477 6.68176206207546 6.08706920660898 8.38782919243786e-09 -14.5781762174566 10.6331568253235 -1.37101111710661 0.172315754666879 C9orf43 other 7.86527660480893e-08 1 0.000102423782268859 6.08706920660898 -1.37101111710661 4.90808848186463e-06 532.654066739066 110.305258576348 4.82890909838528 3.21754976368541e-06 135.885963651163 175.95642883743 0.772270524862211 0.441107841359933 ZNF618 other 0.0417482006267405 1 0.0340030659026274 4.82890909838528 0.772270524862211 0.648027063735922 1.19766411863128 1.73140077365265 0.69173130615197 0.490127755914419 -2.90607099504609 6.24873960471661 -0.465065145753963 0.642529191601023 DGKI other 1 1 1 0.69173130615197 -0.465065145753963 8.25492799381235e-05 72.9947867457088 24.7541313062502 2.94879209626226 0.00367478085499901 -62.5953812322845 40.519301454879 -1.54482873555924 0.124388266974999 TMEM268 other 0.612185460021124 1 1 2.94879209626226 -1.54482873555924 0.000420060233641176 30.0818119017073 8.68569276225884 3.46337508418661 0.000687661019729601 -42.1195499851969 31.230125828083 -1.34868332638358 0.179380899424004 SVOPL other 1 1 1 3.46337508418661 -1.34868332638358 8.89259600079221e-05 650.06556041506 466.796568994639 1.39260997957876 0.165732203092529 -2452.21099023607 758.180988573316 -3.2343345813121 0.0014902652995828 SNX22 other 0.656184658898458 1 1 1.39260997957876 -3.2343345813121 1.04992996094191e-09 206.114437187551 31.2761613315147 6.5901449670508 6.40276863061479e-10 -47.2876350588614 112.430305456662 -0.420595095484192 0.674629591692379 UBN2 other 1.18411100995028e-05 1 8.12895505342854e-06 6.5901449670508 -0.420595095484192 2.03475216792738e-13 169.487290928253 20.3213023048128 8.34037545360034 3.7736432847977e-14 62.0569820168686 71.4237417618348 0.868856496258625 0.386268988408738 BRAF og 2.633986681382e-09 1 5.21102401197715e-10 8.34037545360034 0.868856496258625 0.125002008865615 -1653.98411300034 3375.14169604566 -0.490048792599776 0.624810626664851 -11658.8992795544 6136.236294119 -1.90000820058517 0.0593382974482778 SLC34A2 other 1 1 1 -0.490048792599776 -1.90000820058517 0.582174682070287 -4.70741962530511 5.99596104673645 -0.785098433530903 0.433601991652899 4.17790119101855 10.5354015788731 0.396558323832346 0.692242156032627 ACAN other 1 1 1 -0.785098433530903 0.396558323832346 9.61348328119009e-07 30.8547483022528 43.393461391099 0.711046026592886 0.478190127375078 -293.24380726528 82.4538129538685 -3.55646145108346 0.000507182647171751 PSMG3 essential 0.00878672371900774 1 1 0.711046026592886 -3.55646145108346 2.39566729200283e-12 343.461795848131 48.155876929341 7.13229241681326 3.60788860071033e-11 107.502181328944 84.0556023813134 1.2789412993707 0.202841569536687 WDR19 other 3.00680201819275e-08 1 4.75844427547685e-07 7.13229241681326 1.2789412993707 7.96033500358087e-14 225.048178517665 27.3624300268095 8.22471462867754 7.86401088782552e-14 -85.422442220845 100.609630590213 -0.849048363657888 0.39718087814107 SLC37A3 other 1.04160983521856e-09 1 1.08232381849143e-09 8.22471462867754 -0.849048363657888 7.18804341270833e-08 326.760314111972 63.0171748858638 5.18525806185055 6.64645844727621e-07 -144.066349300804 115.507002499273 -1.24725208154987 0.214186337846851 AP3S2 other 0.000723907852093856 1 0.00734367193839548 5.18525806185055 -1.24725208154987 1.03304194518574e-06 295.522444955057 63.705679726761 4.63887123130273 7.305839819295e-06 -291.951239409919 190.811548955847 -1.5300501516157 0.128003970295414 FMNL2 other 0.00941514428842283 1 0.0750017515848825 4.63887123130273 -1.5300501516157 1.46308873872678e-07 166.229741799285 29.2561200458507 5.68187926282662 6.65737499012785e-08 -29.0144551324914 103.720738773582 -0.279736294549817 0.780062651366028 GAREM2 other 0.00143631421480808 1 0.000780776938842194 5.68187926282662 -0.279736294549817 1.77685751064695e-19 408.979167718164 67.5401082760142 6.0553525624626 1.00609073052019e-08 -569.998826528037 136.820470431924 -4.16603469297123 5.11689406312033e-05 SPPL3 other 2.50305917524836e-15 0.736218717801754 0.000122421120089697 6.0553525624626 -4.16603469297123 0.10079277757322 102.069821292508 53.346520077453 1.91333607411157 0.0576228987015675 -120.393453696549 198.540059121731 -0.606393763702527 0.545176077110925 DPYSL5 other 1 1 1 1.91333607411157 -0.606393763702527 0.239874987515282 -22.7176473732981 20.5282224159512 -1.10665438599524 0.270203273002338 -110.078518158814 72.0987171222427 -1.52677499063093 0.12890889710662 DRC1 other 1 1 1 -1.10665438599524 -1.52677499063093 9.53071527784334e-13 99.0930232558139 19.6080313104531 5.05369568657242 1.24450045685503e-06 -83.1633515985677 36.8355957181084 -2.25768987788311 0.0254083258233231 RAB28 other 1.21116329750833e-08 1 0.0135140304609887 5.05369568657242 -2.25768987788311 0.00341950262541335 3.61729477066949 93.8485899995206 0.0385439437149558 0.969310105100272 -603.934225338397 211.334207391847 -2.85772110815268 0.00493346652922512 FAM213B other 1 1 1 0.0385439437149558 -2.85772110815268 0.0939353002307561 -145.15249780894 68.7952521596732 -2.10992028159213 0.0366834707401079 -256.914747297692 154.917512213674 -1.65839706322766 0.0995252067193675 TNFRSF14 other 1 1 1 -2.10992028159213 -1.65839706322766 1.06606713916129e-09 83.9257960853051 19.5062614973887 4.3025054337829 3.19073960705326e-05 -96.8270737170127 43.9254368419366 -2.2043508426664 0.0291686861230889 PANK4 other 1.20177748597652e-05 1 0.308353075625627 4.3025054337829 -2.2043508426664 0.517277701422994 18.1155089160108 15.7607416298097 1.14940713714558 0.252147288502563 12.9622828029352 26.3309046926833 0.492283989259859 0.623210680533991 MEGF11 other 1 1 1 1.14940713714558 0.492283989259859 3.34474784498149e-16 52.5872123737966 14.714516959888 3.57383205423258 0.000469261780697508 -182.947545571944 31.9631735082293 -5.72369779004709 5.23968758324327e-08 C12orf43 other 4.57059793016721e-12 0.000766042324670167 1 3.57383205423258 -5.72369779004709 1.29980162767939e-13 302.511462963888 55.9175088922368 5.40995958076177 2.75783530251819e-07 -335.317598521552 125.029731322865 -2.68190289600528 0.0082276183956482 PEX10 other 1.69104191761088e-09 1 0.00312104221185984 5.40995958076177 -2.68190289600528 1.93414401710096e-08 288.646121572349 119.965754539684 2.40607098817409 0.0174691285900022 -974.679278757304 268.239525600967 -3.6336154285004 0.000395135209672869 RER1 other 0.000202698292992181 1 1 2.40607098817409 -3.6336154285004 0.0548433353593593 31.1632969616675 12.8073395981359 2.433237341985 0.0161483164143731 41.5760749390049 25.3165099920405 1.64225143797769 0.102646772728012 RADIL other 1 1 1 2.433237341985 1.64225143797769 4.34011924061766e-10 952.894560711252 195.069110166632 4.88490750738171 2.863513030811e-06 -733.69415913291 436.16818625678 -1.68213588760224 0.094837185817073 SKI other 4.99070311478624e-06 1 0.0303761462308431 4.88490750738171 -1.68213588760224 8.66483078363146e-22 613.861434880185 81.3411070281794 7.54675535295483 3.90870610039536e-12 -242.335227684066 160.767214898728 -1.50736720690671 0.133805851941817 WIPI2 other 1.2352582765145e-17 1 5.25330099893137e-08 7.54675535295483 -1.50736720690671 3.78829285502725e-09 94.0637212015165 36.7460466760526 2.55983240947707 0.0114349733729562 -274.393263342082 79.8852902924843 -3.43484091173037 0.000762071154093256 LDLRAP1 other 4.1424982369723e-05 1 1 2.55983240947707 -3.43484091173037 1.53632041067368e-06 338.834626911551 75.8952817541063 4.46450186467906 1.51983207891401e-05 -106.503193509787 166.042408983793 -0.641421635361737 0.522178158464547 AGAP1 other 0.013785403044975 1 0.151618448192462 4.46450186467906 -0.641421635361737 0.11695228262939 113.509190067046 76.0192382013786 1.49316400364807 0.13771058894807 -335.095576697282 291.385891923029 -1.1500061807584 0.25215952188844 KRTCAP3 other 1 1 1 1.49316400364807 -1.1500061807584 2.87180146258152e-07 88.7784622950713 23.4592317205477 3.78437211212297 0.000219751695565299 -65.3943199184079 50.0065087867211 -1.3077161654559 0.192905877062115 PAFAH2 other 0.0027442934776429 1 1 3.78437211212297 -1.3077161654559 0.0266395285430936 17.2818691693651 6.85616515366053 2.52063198333813 0.0127324899927407 9.87024059778634 14.5542881563802 0.678167182876578 0.498683420748116 EXTL1 other 1 1 1 2.52063198333813 0.678167182876578 0.141660948024942 40.6519283063128 26.5463097409868 1.5313589234419 0.127732355055521 -5.76406584486238 56.3525867302898 -0.102285736632639 0.91866294170204 SLC30A2 other 1 1 1 1.5313589234419 -0.102285736632639 0.0280250009474205 18.4581554627762 29.2245678890878 0.631597207282176 0.528586526597774 -126.042172913637 64.9371218678867 -1.94098797864906 0.0540858126139068 WDR66 other 1 1 1 0.631597207282176 -1.94098797864906 0.000353293296467288 23.534646848464 64.7665442316003 0.363376603270755 0.716821900870956 -303.621251012687 104.769177225535 -2.89800167428142 0.00430369586744526 MRPL17 essential 1 1 1 0.363376603270755 -2.89800167428142 0.526150962693527 -6.08419249436921 40.8673770998202 -0.148876510462326 0.881857929875326 -163.465831297783 145.453816729703 -1.12383322055791 0.262940922903755 DUSP2 other 1 1 1 -0.148876510462326 -1.12383322055791 0.00674760251860659 -44.610411041104 21.6494276986529 -2.06058153878496 0.0410143867992545 -154.146114611461 48.0113204824935 -3.21062018420567 0.00161039311470632 GRHL3 other 1 1 1 -2.06058153878496 -3.21062018420567 1.55619308206293e-08 420.315292572818 98.8783468200107 4.25083252390862 3.67771732036825e-05 -283.608035043252 208.999360379293 -1.35698039711011 0.176773063648054 UBXN11 other 0.000164022750849433 1 0.352472427984093 4.25083252390862 -1.35698039711011 3.50281526790601e-06 50.2746925083861 13.2169709443464 3.80379836802859 0.000204122880272061 -19.2392843831532 20.4980824098345 -0.938589473809642 0.349392487427488 PTPDC1 other 0.0302783351757795 1 1 3.80379836802859 -0.938589473809642 0.615103105933604 -8.00496399710563 24.9153065199619 -0.321286996436995 0.748434265547998 -156.790884664234 162.075650415401 -0.967393215837039 0.334884219207874 GALNT14 other 1 1 1 -0.321286996436995 -0.967393215837039 4.09352410931599e-06 190.644263217098 41.2829617664654 4.61798899738731 8.08716426505455e-06 -234.558211473566 157.509221712078 -1.48917129374387 0.138474158470601 NCK1 other 0.0351681902074269 1 0.0827723374854672 4.61798899738731 -1.48917129374387 0.0734699029679686 35.023142718644 27.4449075396048 1.27612536745126 0.203832467062697 -61.0110553392441 60.9827085319422 -1.00046483352387 0.318655021162169 HPD other 1 1 1 1.27612536745126 -1.00046483352387 0.00334142655504051 296.235924932976 95.5215347749012 3.10124754204445 0.00242894441542465 -221.783958891867 397.797102219276 -0.557530353173901 0.578258248278122 RHPN1 other 1 1 1 3.10124754204445 -0.557530353173901 3.42621092471293e-07 274.268351038377 65.9640521551863 4.15784570652417 5.59133476968469e-05 -161.825793855871 146.93467269041 -1.10134518213299 0.272649922518404 TPRG1L other 0.003253386814911 1 0.525641381698058 4.15784570652417 -1.10134518213299 0.00535260660281824 0.862574935769318 9.26604152523564 0.0930899061287535 0.925953132045034 -57.4067993667765 20.5739292254764 -2.79026911863245 0.00593256943749849 LRRC43 other 1 1 1 0.0930899061287535 -2.79026911863245 6.81051574184366e-06 49.54362929441 24.9125648117462 1.98870046776758 0.0484832246946665 -109.714959525782 38.419419483824 -2.85571622371797 0.00487893488664199 AAED1 other 0.057112985011101 1 1 1.98870046776758 -2.85571622371797 0.367516859582468 10.4881466226097 11.0736523483184 0.947126231952041 0.345077747761608 -66.7203336656156 72.0348114276575 -0.926223479221861 0.355798124778973 XDH other 1 1 1 0.947126231952041 -0.926223479221861 2.29874465339109e-12 75.0638026085788 13.5545760797696 5.53789378338526 1.32497242740097e-07 -43.9429205324728 28.5550626069554 -1.53888370469793 0.125925598131095 XKR8 other 2.88699341019387e-08 1 0.0015292831757062 5.53789378338526 -1.53888370469793 5.76704115958096e-07 157.296725083891 33.7021234549453 4.66726452100781 6.78018831803959e-06 -338.874141178926 167.947975913417 -2.01773280884091 0.0454263496866466 CNNM4 other 0.00537026872780179 1 0.0698427198641258 4.66726452100781 -2.01773280884091 3.54268015327636e-14 271.696518961151 44.1316314086721 6.15650295012118 6.40714065198945e-09 -156.207673845033 97.6884028328468 -1.59904010420068 0.111902033436962 EYA3 other 4.67492073026348e-10 1 7.86604657844745e-05 6.15650295012118 -1.59904010420068 0.288063510966935 -8.40621059617298 7.96797599003459 -1.05499948878943 0.293067244004099 -42.3396674409173 31.2915428964963 -1.35307062297839 0.178003283908724 DZIP1L other 1 1 1 -1.05499948878943 -1.35307062297839 8.11948480104023e-12 165.333580891313 24.7045242461901 6.69244140238042 3.78548448905618e-10 7.2985026228944 37.8554959689262 0.192799022601247 0.847368757450567 FANCC other 1.00105128112025e-07 1 4.8378491770138e-06 6.69244140238042 0.192799022601247 0.000568521559548391 138.253809402964 35.4893726365393 3.89563971217175 0.00014531240043241 2.91549249153177 139.67572407072 0.0208732942744984 0.98337357612836 MRAS other 1 1 1 3.89563971217175 0.0208732942744984 9.03077012146851e-16 1511.91381318568 231.299604296612 6.53660354406334 8.99167172441391e-10 -1120.55955263109 509.742859598538 -2.19828396127729 0.0294409453123585 WASF2 other 1.22637858249542e-11 1 1.13654730596592e-05 6.53660354406334 -2.19828396127729 0.213601720189782 -21.2837811141841 22.0631069100242 -0.964677422857158 0.336497496857972 -108.765902805215 61.5627502375525 -1.76674860017656 0.0796171821980312 ABHD3 other 1 1 1 -0.964677422857158 -1.76674860017656 1.47638992812183e-08 31.466512561927 4.966221096718 6.33610786735251 2.43848705562756e-09 10.067888838624 19.5455843833427 0.515097867690472 0.607218442897751 ESYT3 other 0.000155832956913259 1 3.03811102260638e-05 6.33610786735251 0.515097867690472 0.000768281564377536 37.8449206121526 12.9141175756314 2.93050767042457 0.00389611783464947 -99.0159217044939 50.8261653871439 -1.94812890074015 0.0532060109217002 FAIM other 1 1 1 2.93050767042457 -1.94812890074015 0.0307374179646555 26.554741197924 20.3825419288542 1.30281793559478 0.194594370779036 -47.4353415626314 42.9789694544845 -1.10368727228014 0.271461655212537 FAM46B other 1 1 1 1.30281793559478 -1.10368727228014 0.355627993766329 56.8373833790436 39.4588488881136 1.4404217299954 0.151818343290498 23.6425759807738 159.048188088999 0.148650394983085 0.882027838215877 CLSTN2 other 1 1 1 1.4404217299954 0.148650394983085 0.23629606040923 -67.6688306392418 49.8032224685288 -1.3587239396407 0.176419186876875 22.6215900008453 131.676161288246 0.171797155836927 0.863845081703312 COLEC12 other 1 1 1 -1.3587239396407 0.171797155836927 0.00064851081801394 104.274670303126 55.7058919818494 1.87187865759517 0.0632376540433093 -227.213418123135 126.966249119999 -1.78955761627951 0.075612250834834 RNF207 other 1 1 1 1.87187865759517 -1.78955761627951 0.000321717408233229 145.346902099986 59.5816885367848 2.43945590783738 0.0159166211376149 -184.729275095166 135.800060650971 -1.36030333277944 0.175844948664367 GPR153 other 1 1 1 2.43945590783738 -1.36030333277944 0.575888580557967 8.23013298735003 12.6091495152268 0.652711190188627 0.514922007208783 -33.2294717932084 56.2410007383825 -0.590840691967461 0.555498962094851 SLC13A3 other 1 1 1 0.652711190188627 -0.590840691967461 0.041342631388666 7.36784320842033 8.232921146332 0.894924544698562 0.372242369548183 -86.899212614302 42.4037622887414 -2.04932788799673 0.042149310123635 RHBDL2 other 1 1 1 0.894924544698562 -2.04932788799673 8.2825981752269e-05 318.133283273887 76.4779025565486 4.15980659300451 5.41321627062653e-05 -268.465296858201 302.644610022056 -0.887064523761504 0.376503067735055 AUTS2 other 0.613906176747818 1 0.510087369181138 4.15980659300451 -0.887064523761504 0.212686055885234 80.6294254709278 46.706469929004 1.72630099413397 0.0863522243357887 46.1388702497512 132.47188017345 0.348291804942602 0.728109378085817 HIST1H2BD other 1 1 1 1.72630099413397 0.348291804942602 0.0205988510595254 54.3134455171155 19.809493714313 2.7417886746834 0.00682958436181561 22.9343320008896 29.4836631813014 0.777865757720178 0.437833870433006 CDC25C other 1 1 1 2.7417886746834 0.777865757720178 0.274377496551047 34.0326203995631 37.5849122099718 0.905486228341748 0.366689567933757 -113.92785515644 115.834451041071 -0.983540338237066 0.326957594608761 HIST1H4H other 1 1 1 0.905486228341748 -0.983540338237066 5.76594091876812e-23 117.927530603943 10.3392869985855 11.405770109687 3.98605245050269e-22 -71.242247309442 47.9519041992649 -1.48570215300301 0.139442736609035 MITD1 other 8.25682739567595e-19 1 5.73553087102832e-18 11.405770109687 -1.48570215300301 2.78526906785643e-29 2041.67397093088 143.417809472446 14.2358468480383 1.05958083924145e-29 325.307162801879 665.148095921117 0.489074786196875 0.625498385003707 EIF5B other 4.03362666406968e-25 1 1.53702796540365e-25 14.2358468480383 0.489074786196875 0.375375362805191 7.52518836701641 9.27278377144479 0.81153497725138 0.418397910336277 -17.42140412647 23.9543890165064 -0.727273992021475 0.468238873472562 CATIP other 1 1 1 0.81153497725138 -0.727273992021475 7.21976535911642e-06 204.070978216481 51.0169234471962 4.00006437917997 9.80551299415621e-05 -217.598968760687 142.560520036116 -1.5263620580618 0.128970901988443 CNOT11 other 0.0604077767597271 1 0.898184990264709 4.00006437917997 -1.5263620580618 0.339912266940572 6.71780952665016 16.6277082366212 0.404012954223884 0.686767344609085 -98.6130879589585 79.7547219416318 -1.2364545390946 0.218184364275932 KCNB1 other 1 1 1 0.404012954223884 -1.2364545390946 0.324163504377353 55.8673933578605 37.5241199126975 1.48883953808484 0.138548436273917 75.8350361274075 133.179084269805 0.569421516473074 0.569889121765258 TSPAN33 other 1 1 1 1.48883953808484 0.569421516473074 0.0287831295633825 -12.7294683612829 16.7435676661807 -0.760260215449448 0.448292385895601 -64.3349963704368 24.4257072201586 -2.63390516354592 0.0093258942073139 NRG2 other 1 1 1 -0.760260215449448 -2.63390516354592 6.06880001381679e-05 80.9743300557562 17.8332138757797 4.54064705441189 1.11531395723898e-05 52.8228599113625 61.8244295673815 0.854401088388397 0.394192959619381 AHCYL2 other 0.457162705040819 1 0.112758241076861 4.54064705441189 0.854401088388397 0.0433808654332536 347.61046606041 153.801236783837 2.26012789837943 0.0252433362365031 -303.838299772652 736.85162351956 -0.412346651719886 0.68067018262607 B4GALT5 other 1 1 1 2.26012789837943 -0.412346651719886 7.43543018038701e-16 134.412253942673 16.3178262937853 8.2371420998558 7.31842219211214e-14 -147.573667549211 78.867406445621 -1.87116166487563 0.0632321599783255 SPATA2 other 1.01151592173985e-11 1 1.00767355163192e-09 8.2371420998558 -1.87116166487563 1.37451545521014e-07 69.3291906998869 12.4618252917634 5.56332552228202 1.13482985909699e-07 -14.1481767787887 44.6876380609117 -0.316601579154931 0.751971927979927 FAM86C1 other 0.00135279811101782 1 0.00131504084072159 5.56332552228202 -0.316601579154931 0.0834807969303249 -1.86989332463781 15.7673561114875 -0.118592699461864 0.9057496490427 -88.59495621186 42.8429125188166 -2.06790227375296 0.0402898762277192 DNAH3 other 1 1 1 -0.118592699461864 -2.06790227375296 0.527867259211948 -9.38056787932564 10.1401282338281 -0.925093614500012 0.35645425286296 19.4661208356861 41.4943031571092 0.469127551364867 0.639683075329637 NCF1 other 1 1 1 -0.925093614500012 0.469127551364867 6.8307824071193e-18 325.614205018814 33.6197494528359 9.6852061754835 1.48813513632662e-17 -11.2319118549102 107.931142554759 -0.104065532792926 0.917255435972428 PPP1R9A other 9.51049834543219e-14 1 2.10943155574298e-13 9.6852061754835 -0.104065532792926 6.09329043007408e-17 429.525969866932 55.9109952788169 7.68231664854064 2.03149786213079e-12 -15.8453300929609 98.4520582851669 -0.160944629995087 0.872357984980334 ZC3H18 essential 8.40386616115817e-13 1 2.74516306109734e-08 7.68231664854064 -0.160944629995087 6.51619177816406e-06 95.747250853183 22.8374698817881 4.19255072250964 4.88334001476919e-05 -50.0284911579168 57.0565678856756 -0.876822651831408 0.382095850266747 ZFAND2B other 0.0547555595119126 1 0.462598799599086 4.19255072250964 -0.876822651831408 0.00076552788138078 152.153537135019 47.1936936514043 3.22402264715492 0.00154527646639743 -202.191267580156 169.835088580497 -1.19051527732047 0.235687779221705 GDPD5 other 1 1 1 3.22402264715492 -1.19051527732047 0.0355576151394616 10.3628719781868 4.42463693612662 2.34208413657068 0.0204650272164981 -4.90341069696853 13.9419936307223 -0.351700827503139 0.725546540179386 DYNC1I1 other 1 1 1 2.34208413657068 -0.351700827503139 1.913158628049e-08 563.812208158644 128.85764475125 4.37546572612778 2.28433140316531e-05 -552.693875388293 299.960275310628 -1.84255690129616 0.0674082654254726 TMED4 other 0.000200594682150938 1 0.223910164138263 4.37546572612778 -1.84255690129616 1.43377289290211e-08 304.285837922896 53.1868467995726 5.72107308917101 5.35612032604688e-08 -310.290873328089 198.603292561574 -1.56236520213726 0.120254620867154 PPP1R15B essential 0.000151478106135108 1 0.000631165219221364 5.72107308917101 -1.56236520213726 1.00031889722738e-12 279.358716458798 36.5106766469803 7.65142533949457 2.1778090856331e-12 -124.808925745691 137.551983204261 -0.907358242595119 0.365663128165059 COPG2 other 1.27030496758905e-08 1 2.94156673196462e-08 7.65142533949457 -0.907358242595119 3.30245727365685e-05 133.743049386132 28.9605300565618 4.61811469351299 8.19133413379972e-06 21.8368116744099 105.1946470276 0.207584818157911 0.835831019377254 EMSY other 0.257492593627025 1 0.0837645828522359 4.61811469351299 0.207584818157911 2.87221569147314e-14 427.73826260106 50.1306639543533 8.532467533056 4.23433539645356e-14 211.942086702013 142.639601894291 1.48585725063283 0.139854932051713 GPAT4 other 3.79620747942005e-10 1 5.84380628064556e-10 8.532467533056 1.48585725063283 0.433011557457174 -1.02231418247572 5.32505604989115 -0.191981863270081 0.848009324609957 13.2787376634882 12.7466853747426 1.04174044256241 0.299164685308309 PKD1L1 other 1 1 1 -0.191981863270081 1.04174044256241 7.16147690282444e-11 60.2928337898736 10.0482133601452 6.00035365779715 1.36952982150821e-08 -37.8557672482741 28.6111378350413 -1.32311295924451 0.187771765421946 ZSCAN12 other 8.53003513895419e-07 1 0.000165672022507848 6.00035365779715 -1.32311295924451 0.000884549708524869 91.4244400360684 27.3247824560169 3.34584329017913 0.00103065980444048 -107.846708746619 100.470157958256 -1.07342031642299 0.284761678254668 ELK4 og 1 1 1 3.34584329017913 -1.07342031642299 0.228165169338902 23.1776646981121 20.9158567126143 1.10813843375269 0.269518596014666 -82.0060236862054 78.8543562745616 -1.03996820924731 0.299974169595942 SLC45A3 other 1 1 1 1.10813843375269 -1.03996820924731 0.00486590997051583 40.7158078880407 22.6017114000818 1.80144800397254 0.0737391957595399 -43.8011688931297 39.5206936013905 -1.10830972084935 0.269588671156283 RNF166 other 1 1 1 1.80144800397254 -1.10830972084935 0.825328379680945 -17.4742432659706 339.75222130811 -0.0514323149932366 0.959047257387324 -392.577206451555 749.953587234715 -0.523468669440058 0.601395744573191 NBL1 other 1 1 1 -0.0514323149932366 -0.523468669440058 2.01188097204679e-10 144.459720135379 25.2076217982054 5.73079528453031 6.16142635218827e-08 -1.83906266599878 44.5669715124172 -0.0412651477896895 0.967145036215877 SPATA2L other 2.35088291583667e-06 1 0.000724214053436209 5.73079528453031 -0.0412651477896895 2.14495155136797e-09 267.56818740305 47.1865130045669 5.67043780872628 8.2918539087703e-08 38.1913040807237 83.4221691639545 0.457807612334607 0.647826656996201 ZNF276 other 2.37939475593249e-05 1 0.00096707892137988 5.67043780872628 0.457807612334607 0.000910018709486841 7.16723166258514 4.32354487290055 1.65772112312479 0.0994919173557235 -8.71070426652124 7.66786099078571 -1.13600184940607 0.257791970280983 NPM2 other 1 1 1 1.65772112312479 -1.13600184940607 1.65001080625043e-10 1075.8038832629 159.173859999122 6.75867182757793 3.33279813019392e-10 904.80192967068 287.012721773715 3.15248022484536 0.00197544930519555 FGF17 other 1.93397766600613e-06 1 4.2673147259003e-06 6.75867182757793 3.15248022484536 0.666158968791154 0.846607105452486 14.3742030686578 0.0588976725463457 0.953109477170474 -21.6435070080052 31.7289615163521 -0.682137264305069 0.496170248511485 CDA other 1 1 1 0.0588976725463457 -0.682137264305069 4.49166348401322e-17 720.467696799115 116.193648974866 6.20057725319361 5.86145578778597e-09 -151.299700799212 209.62409053699 -0.721766760736472 0.471633114114322 DMTN other 6.20029227333185e-13 1 7.20490145434652e-05 6.20057725319361 -0.721766760736472 9.40340687752358e-12 358.464349943949 84.0528218216777 4.26475092893905 3.64637634581395e-05 -196.26022403768 151.639065361036 -1.29425899302667 0.197691730130246 FAM160B2 other 1.15746535255438e-07 1 0.3496510278001 4.26475092893905 -1.29425899302667 2.33472669695517e-27 1095.67389587627 130.525123781211 8.39435247510556 3.3579229783748e-14 -301.281213685421 241.546962164125 -1.24729870740708 0.21424491459905 CCAR2 other 3.37601480379717e-23 1 4.63930638692262e-10 8.39435247510556 -1.24729870740708 2.01007715623027e-06 296.884667631337 63.4751204202325 4.67718163692851 6.25933049340314e-06 -265.936937069958 212.895034238263 -1.24914579629102 0.213482845010564 CACHD1 other 0.0178273742986062 1 0.064683921318828 4.67718163692851 -1.24914579629102 1.62869741255585e-07 186.45169218166 64.5401143809976 2.88892720395544 0.00442693902463339 -275.31483282986 98.9452941956688 -2.78249546952089 0.00607400136467079 CDC42SE2 other 0.00159319180896213 1 1 2.88892720395544 -2.78249546952089 1.81003296021731e-08 85.2758250416714 18.3816842577571 4.63917363860086 7.45909394803504e-06 -32.5583161242242 28.1806311336686 -1.15534375258634 0.249750791623753 RAPGEF6 other 0.000190125862141226 1 0.0765134590728506 4.63917363860086 -1.15534375258634 8.39553905710767e-09 299.69487107451 64.6135317640123 4.63826791219344 7.52205813614315e-06 -164.313143235214 149.394836984158 -1.09985824511886 0.273132768633647 EPB41 other 8.99162233016231e-05 1 0.0771462282442842 4.63826791219344 -1.09985824511886 3.23232942173128e-09 146.43216763519 28.0972491233124 5.21161936503225 6.22900106952753e-07 -84.7111513897137 55.3058710698564 -1.5316846069148 0.127749531417126 MIS18A other 3.55071386977181e-05 1 0.00689861868450174 5.21161936503225 -1.5316846069148 4.15000843413994e-05 256.701325148839 55.2171301412235 4.64894362478272 7.32700951154104e-06 205.404994763905 204.370501510354 1.00506185210637 0.31650747168815 ALG8 other 0.318762147826289 1 0.0752117526359688 4.64894362478272 1.00506185210637 0.00571106600159151 283.3102936814 188.396306120225 1.50379962068155 0.135196332220829 -534.210345158531 293.819863366368 -1.81815599203522 0.0714737501637863 FBXW5 other 1 1 1 1.50379962068155 -1.81815599203522 3.11460333003159e-06 228.844228533138 58.2989815943557 3.92535550835924 0.000131932167805533 -211.673203129619 130.238215567398 -1.62527720613677 0.106216858226863 C21orf59 other 0.0270472153179943 1 1 3.92535550835924 -1.62527720613677 1.98704203802482e-05 46.1811106399296 10.831438776882 4.26361738188428 3.56775372321045e-05 -8.8378350926463 23.9383466411184 -0.369191541301592 0.712512620150818 SYNJ1 other 0.158983233462366 1 0.342647067577131 4.26361738188428 -0.369191541301592 2.83653163984433e-10 187.037612141927 29.0505334300762 6.43835379450505 1.58715043715679e-09 -18.0475865203689 64.2040040740321 -0.281097523132026 0.779028202899363 PAXBP1 essential 3.29122766171137e-06 1 1.98965178801975e-05 6.43835379450505 -0.281097523132026 0.0317310828150724 98.3269426577594 52.224516183182 1.88277364433342 0.0617205720565889 -107.030118404097 112.072826646962 -0.955005076665466 0.341153690289241 IFNAR2 other 1 1 1 1.88277364433342 -0.955005076665466 8.2890094354155e-13 344.25049153559 50.8980172575744 6.76353441811842 2.59403476795614e-10 -884.164264529459 210.044680343242 -4.20941041251134 4.32326174308481e-05 MRPL10 essential 1.05502512093969e-08 0.622722621473936 3.33489109768442e-06 6.76353441811842 -4.20941041251134 0.0200042596428091 200.77884673135 112.71969387312 1.78122242735463 0.0769411442820404 -314.500371282399 241.752634444063 -1.30091807274666 0.195322019934329 IFNGR2 other 1 1 1 1.78122242735463 -1.30091807274666 1.42534637338111e-07 470.194575098668 98.1206503812843 4.79200426486731 4.11321083457531e-06 -282.393360039025 211.656143949553 -1.33420818677643 0.184271349636146 GART other 0.00140111548503363 1 0.0431599212871987 4.79200426486731 -1.33420818677643 0.00176760406564009 85.5516065545711 37.2752960279038 2.29512882984292 0.0232450388984693 -112.554100885638 69.3617331137689 -1.62271177251329 0.106949981985737 DONSON essential 1 1 1 2.29512882984292 -1.62271177251329 0.633528358419611 78.8337276955226 200.377997972748 0.393425069084902 0.694549694200309 -598.909434775422 791.029293037448 -0.757126746186211 0.450130778235464 LAD1 other 1 1 1 0.393425069084902 -0.757126746186211 0.561920472598872 -143.229635261506 211.129605780893 -0.678396735179561 0.498538304605732 -410.02638873686 385.121146716514 -1.06466859125416 0.288692394357222 STC1 other 1 1 1 -0.678396735179561 -1.06466859125416 0.809882566500628 32.5056560363008 81.4018843741386 0.399323139583582 0.69021196561535 -125.179801696354 308.994182345494 -0.40512025419426 0.685954998430409 TNNI1 other 1 1 1 0.399323139583582 -0.40512025419426 0.529802568619855 -491.95935323065 436.033849874326 -1.12825954538264 0.260976412833531 -522.099640277918 1655.14501233929 -0.315440421464951 0.752857122761866 CSRP1 other 1 1 1 -1.12825954538264 -0.315440421464951 0.912548668089793 7.13678211874152 21.013407169142 0.339629935369159 0.734592046792012 23.3281999884354 86.5687453355281 0.26947600889927 0.787919509440521 HOXB13 other 1 1 1 0.339629935369159 0.26947600889927 0.830615801993401 -27.4794792843392 470.908264727884 -0.0583542089672568 0.953543133656677 -515.813563393253 1007.64923165257 -0.511897937486945 0.609465362053538 C1QC other 1 1 1 -0.0583542089672568 -0.511897937486945 0.00568470821362028 5.70888873140531 2.26429767495408 2.5212624623311 0.0127453162668196 -3.44062260419149 4.39813498808032 -0.782291269712309 0.435284862415141 KCNE2 other 1 1 1 2.5212624623311 -0.782291269712309 1.6307946792278e-05 779.11992999794 172.219631967336 4.52399021585246 1.1910254489522e-05 -1182.26369157916 706.498319094362 -1.67341331129375 0.0962372380628023 ATP5G1 other 0.131702978294437 1 0.12011491652683 4.52399021585246 -1.67341331129375 0.450106057026547 -30.4017484972845 43.9580826081578 -0.691607702007515 0.490259956986898 -107.294422718868 85.3834649332424 -1.2566182785245 0.210858368358579 RCAN1 other 1 1 1 -0.691607702007515 -1.2566182785245 3.86939139334285e-11 1029.66136504015 137.498503093853 7.4885278157343 4.71698997635730e-12 88.8919857936967 564.061484768602 0.157592723832515 0.874980236562657 UBE2Z other 4.65874723758479e-07 1 6.33255904325968e-08 7.4885278157343 0.157592723832515 1.35900960003252e-12 309.946211653284 38.3533768809006 8.08132782194812 1.60370707551467e-13 70.6193380687661 157.337441663376 0.448840004783201 0.654165980816759 SNF8 essential 1.71901124308113e-08 1 2.19948425406838e-09 8.08132782194812 0.448840004783201 0.844997946159208 22.8430829988597 39.4116901932288 0.579601709210235 0.563058571177131 16.8175867645069 76.552626227352 0.2196866076751 0.826415916997851 CLIC6 other 1 1 1 0.579601709210235 0.2196866076751 3.47900126518992e-06 124.020595626069 27.7644598272449 4.46688307273924 1.54663488646339e-05 -150.650043288825 112.404093169203 -1.34025406941409 0.182175905982084 CCDC24 other 0.0300759659375669 1 0.154106700087213 4.46688307273924 -1.34025406941409 0.726352797117975 26.7069178505251 52.7549446200616 0.506244827719315 0.613394930252604 136.955991352688 216.417137072146 0.632833393905543 0.527763093790239 IGF2BP1 other 1 1 1 0.506244827719315 0.632833393905543 0.00442897484096899 -35.2707354160905 73.8578189382911 -0.47754910614893 0.633661685258339 -459.815228592254 144.044645030455 -3.19217162495028 0.00171834049087574 CBR1 other 1 1 1 -0.47754910614893 -3.19217162495028 0.0105121465897841 -30.4409731821951 11.9208639688576 -2.55358783236853 0.0116530258497037 -61.4068916982934 23.2492191555929 -2.64124533763196 0.00912924788014072 CBR3 other 1 1 1 -2.55358783236853 -2.64124533763196 0.470106282807788 9.19716461013391 7.58613045987576 1.21236573227671 0.227265886357766 5.20458423828731 11.126033755022 0.467784329338213 0.640613258944299 ACTC1 other 1 1 1 1.21236573227671 0.467784329338213 4.67661909553093e-05 90.3420968237638 27.3142343987788 3.30750975864083 0.00118165618463927 -75.5275799404036 52.5403435632754 -1.43751591288024 0.152682376032041 MORC3 other 0.357200166516653 1 1 3.30750975864083 -1.43751591288024 0.00229139013473017 46.0996899929181 28.7580979672897 1.60301595903016 0.11106319026888 -118.713103144166 55.3176898670566 -2.14602423617953 0.0335015944611269 CHAF1B essential 1 1 1 1.60301595903016 -2.14602423617953 0.214530597480541 80.9400621118013 69.4215894388553 1.16592061296855 0.245484824052793 -89.6094767551288 136.409568118979 -0.65691489234076 0.512235606781229 SIM2 other 1 1 1 1.16592061296855 -0.65691489234076 1.27693994821041e-10 164.937545535754 33.1924404977293 4.96912980975404 1.80241839134123e-06 -162.661879209087 63.3458996654637 -2.56783596204524 0.011204353585071 HLCS other 1.50474603497115e-06 1 0.0193850097988749 4.96912980975404 -2.56783596204524 0.330481052478976 22.1045948309148 34.0460291727874 0.649256179589446 0.517139943906443 76.8216184707022 52.3567137615787 1.46727349658597 0.144340943813871 SCUBE1 other 1 1 1 0.649256179589446 1.46727349658597 0.0138284532681941 95.4060757696435 42.4647868951973 2.24671033920657 0.0260528810665044 -294.720244485232 171.182258067204 -1.72167517716426 0.0870979761990096 ARHGAP27 other 1 1 1 2.24671033920657 -1.72167517716426 2.73793485261513e-06 334.273085400919 65.5984795273371 5.09574441068587 1.02387376624467e-06 74.5197084912784 113.802193718627 0.65481785593278 0.513581262094437 ADPGK other 0.0239322885467088 1 0.011185820896223 5.09574441068587 0.65481785593278 1.90320940383645e-08 3114.26154297237 535.501686958587 5.81559613875354 3.66742976444475e-08 -1472.19607621242 2347.77677431774 -0.627059647372243 0.531599498907256 PTMS other 0.00019957053808629 1 0.000435543958825458 5.81559613875354 -0.627059647372243 0.00168112638440886 290.575559855581 137.334443936282 2.11582434476814 0.0362817999744511 -1052.07552445902 475.638804244556 -2.21192113652292 0.0287323867004324 ADIPOR1 other 1 1 1 2.11582434476814 -2.21192113652292 0.393335162871188 25.0357859216083 78.8871354420683 0.317362086749793 0.751481959708476 -321.100962786417 273.214655380644 -1.17526990760821 0.242051420386763 CYB5R1 other 1 1 1 0.317362086749793 -1.17526990760821 1.20272516089722e-14 583.128346710578 82.0965543730739 7.10295762305261 4.23416905737591e-11 -90.9205368555604 179.996314017843 -0.505124437417909 0.614193555313704 ATP13A2 other 1.60166909676682e-10 1 5.5755538147526e-07 7.10295762305261 -0.505124437417909 0.70189712849806 10.7776291142628 19.2252550112955 0.56059745932788 0.575891983758583 -1.65258365753407 29.8828077922876 -0.0553021546375769 0.955969895286694 IRX6 other 1 1 1 0.56059745932788 -0.0553021546375769 0.233179536186684 101.596244731128 240.640288082242 0.422191336042642 0.673489878607668 -1266.11346952883 838.575250933974 -1.50983882259663 0.133188169183836 BTG2 other 1 1 1 0.422191336042642 -1.50983882259663 0.00797072802968949 786.99970870428 270.538753277096 2.90900914996901 0.00418529325754653 -381.74171172647 1110.38497528864 -0.343792216413266 0.731490487135953 C1R other 1 1 1 2.90900914996901 -0.343792216413266 1.80121555263435e-07 107.178350670888 31.9504593616091 3.35451673660977 0.000999611506413909 -161.398963905655 72.1701498115844 -2.23636731151344 0.0267552722279142 ALDH4A1 other 0.00175546467759744 1 1 3.35451673660977 -2.23636731151344 0.0001099168413023 91.1290255066905 20.6417061439334 4.41480102813464 2.02445899957655e-05 73.4729404933904 31.7266369544553 2.31581243857845 0.0220424119201117 STARD9 other 0.802722692030698 1 0.199672391128235 4.41480102813464 2.31581243857845 7.81267041372358e-14 166.906078965083 22.6307992273046 7.37517386322386 1.53619733158165e-11 -0.541180086048003 35.3288062732529 -0.0153183801870409 0.987800962931348 UBR1 other 1.02252230374814e-09 1 2.04083815500622e-07 7.37517386322386 -0.0153183801870409 3.45739583521494e-09 647.312862559114 152.911195809684 4.23326009015567 3.94473052721564e-05 -170.113587342417 237.688822525512 -0.715698725480279 0.475261155582491 AMFR other 3.79172601248022e-05 1 0.376800659959638 4.23326009015567 -0.715698725480279 7.52800279493046e-13 243.12436639189 33.9033579658836 7.17109988445812 3.03656856063839e-11 -268.094606010957 155.845039252473 -1.72026397052418 0.0874196065592636 MED8 essential 9.59067556074141e-09 1 4.00918147061087e-07 7.17109988445812 -1.72026397052418 6.97833237098951e-38 42.5238757936851 2.40675255943204 17.6685698856056 1.11466245442306e-38 52.5396842654606 13.3152931081419 3.94581507434743 0.000121171636322324 RGL4 other 1.01583584324494e-33 1 1.62294853363998e-34 17.6685698856056 3.94581507434743 3.35192295598159e-08 151.945713570593 39.8329236690691 3.81457597320633 0.00019838278440693 -51.9445365190393 63.80160807235 -0.814157167639646 0.416836992723939 RSPRY1 other 0.000345214545236543 1 1 3.81457597320633 -0.814157167639646 0.171846989053916 -22.846964890097 17.2541798673733 -1.32414087865743 0.187405574743611 -91.0091768821315 54.3560767978144 -1.67431467176437 0.0960853892038412 CCDC17 other 1 1 1 -1.32414087865743 -1.67431467176437 6.11315206618256e-12 632.815262245307 105.13239328092 6.01922245367693 1.21931590779849e-08 -1000.12547796261 331.20000411736 -3.01970249254048 0.00295984509083445 GPBP1L1 other 7.57052751876048e-08 1 0.000147890826456878 6.01922245367693 -3.01970249254048 2.58744174417067e-13 304.175022301516 57.9198324075536 5.25165577416013 5.3101524519994e-07 -89.7462682129051 90.8808092454585 -0.987516164942049 0.325046048848164 NAE1 essential 3.34090478007317e-09 1 0.00590648257235894 5.25165577416013 -0.987516164942049 6.94896674258499e-07 215.750637914455 46.9795520226913 4.5924371056209 9.00915695672331e-06 -248.716659978345 148.000319766058 -1.6805143419385 0.0948714667464895 TMEM69 other 0.00642431975351983 1 0.0918123185459672 4.5924371056209 -1.6805143419385 0.3783926254974 4.98956342789948 8.4795488353387 0.588423219771478 0.557139152873815 -6.85756283992351 12.9733399116996 -0.528588851182358 0.597877166103615 ADGRG5 other 1 1 1 0.588423219771478 -0.528588851182358 0.0094376292618443 -9.36206510210486 23.3968536102241 -0.400142055768293 0.689628847385704 -90.6915343362065 35.9202027715577 -2.52480574547362 0.0126300581435246 DRC7 other 1 1 1 -0.400142055768293 -2.52480574547362 0.614920133358017 -41.967619758882 44.1773757266961 -0.949979917741497 0.34360134280356 -52.5152032433578 179.254385985652 -0.292964676733552 0.769940993174467 ACE other 1 1 1 -0.949979917741497 -0.292964676733552 0.218205748461595 8.1755113205959 6.62069342091912 1.23484215335573 0.218833008088899 -0.785077013719372 10.3677686268009 -0.0757228524265027 0.939741170280378 TEPP other 1 1 1 1.23484215335573 -0.0757228524265027 5.76157298308237e-07 629.08872453271 172.178773128455 3.65369501188963 0.000353226948994035 -1715.68212371664 565.140637169687 -3.03584985908826 0.00281434503423386 EFCAB14 other 0.00536603055083717 1 1 3.65369501188963 -3.03584985908826 0.398523345668575 -101.609189029115 117.614306025912 -0.863918620637263 0.389142621784208 -286.809288581131 211.306907054832 -1.35731146974153 0.176914072499179 SPON2 other 1 1 1 -0.863918620637263 -1.35731146974153 0.0197143978862893 28.4050642464952 10.646060956764 2.66812902554798 0.0084837861589159 -24.5894325050158 44.9456362960684 -0.547092766537754 0.585144588097125 CHCHD6 other 1 1 1 2.66812902554798 -0.547092766537754 9.29088763395482e-12 1110.57935177776 204.169412013025 5.43949919249858 2.38424169275568e-07 -544.791977241653 366.812579399746 -1.48520527331193 0.13978685886928 CTBP1 other 1.14380117661618e-07 1 0.00270992910798611 5.43949919249858 -1.48520527331193 0.00687855740821714 0.609129066106996 7.02111106620141 0.0867567911066459 0.930988794556574 -24.6343876480288 11.0040350120511 -2.23866859938653 0.0267555343112679 LRRC36 other 1 1 1 0.0867567911066459 -2.23866859938653 0.0464749231097436 -66.5595113176449 361.014841651468 -0.184367797770217 0.853991721982543 -1084.74510139838 565.810727097942 -1.91715188392073 0.0572556750335175 TPPP3 other 1 1 1 -0.184367797770217 -1.91715188392073 0.000121930367182324 36.857742467396 55.1770402576134 0.667990568093408 0.505239352218312 -228.040377326166 86.4777778233642 -2.63698239092073 0.00930983661660171 ZDHHC1 other 0.885092535376491 1 1 0.667990568093408 -2.63698239092073 6.27664021979839e-06 268.433818018289 141.618222464492 1.89547512563642 0.0600907471557082 -460.636464869262 221.955166874582 -2.07535815162866 0.0397833563118023 ATP6V0D1 other 0.0528304807300431 1 1 1.89547512563642 -2.07535815162866 0.00219994591219956 37.1102446681513 16.8394838204782 2.20376378894834 0.0290450076049767 -33.2260184979588 31.8967799295439 -1.04167312723576 0.299217247941366 ZFYVE28 other 1 1 1 2.20376378894834 -1.04167312723576 0.923081567629154 -3.10999555423832 24.4506265481121 -0.127194922719821 0.89896733908272 -13.8056514099416 38.3287079671904 -0.360190889339639 0.719243362435492 CARMIL2 other 1 1 1 -0.127194922719821 -0.360190889339639 0.000980983453126356 13.0831441102367 4.09771881728278 3.19278718077396 0.00173304150458948 5.12319201219324 6.53965792053321 0.783403669495838 0.434685668818154 C16orf86 other 1 1 1 3.19278718077396 0.783403669495838 0.135114433971016 5.68628556694719 3.98449956835319 1.42710156429942 0.155656994200325 -16.1934151874737 16.3762498595686 -0.98883537600716 0.324357563138528 FAM131B other 1 1 1 1.42710156429942 -0.98883537600716 3.0329794291262e-14 350.582722715003 44.8518137429255 7.81646701568007 9.59785181041594e-13 112.939066718087 85.1403274950892 1.32650495999797 0.186729609458889 RGS12 other 4.00686912381862e-10 1 1.30396414696311e-08 7.81646701568007 1.32650495999797 1.21774699649341e-14 370.937764229234 69.4103058881557 5.34413095408259 3.44815198387304e-07 -146.66945901511 111.330872765556 -1.31741946660178 0.18977597272646 PSKH1 other 1.62130835113132e-10 1 0.00387882616665879 5.34413095408259 -1.31741946660178 0.000496999087985304 1503.79991959034 406.043652086096 3.7035424931886 0.000302210997791164 -598.267935084854 1582.8210031736 -0.377975736918647 0.706005198296974 ZYX other 1 1 1 3.7035424931886 -0.377975736918647 0.000346571894609111 85.0497002973288 70.1242928580009 1.21284218109053 0.227262247159463 -1052.60448746568 295.1948079493 -3.56579607472793 0.0004990678661633 ABR other 1 1 1 1.21284218109053 -3.56579607472793 0.60142042496961 2.56422371239372 5.29218712610793 0.484530053698148 0.628685019320331 -8.24353093661411 15.0443594785704 -0.547948282434784 0.584505626846197 LYPD5 other 1 1 1 0.484530053698148 -0.547948282434784 1.36719819554345e-06 293.009287658214 61.5615927591655 4.75961187041558 4.72490870151413e-06 -28.6175644736271 97.729272919608 -0.292824899016366 0.770083456837944 CCDC117 other 0.0123225573364331 1 0.0493705710221211 4.75961187041558 -0.292824899016366 2.83938077756147e-12 8.64734581116223 2.02063273892671 4.27952375737286 3.25678426970005e-05 -43.2965192563113 8.8448978411025 -4.89508415293516 2.4310458759911e-06 ZNF230 other 3.55575654774023e-08 0.0354252005049424 0.314336097577083 4.27952375737286 -4.89508415293516 1.92831077597917e-05 44.988493500959 22.4810026834754 2.00117824522248 0.0473062495495135 -170.352283125055 58.5638822524951 -2.90882838659141 0.00422078249797215 CCDC107 other 0.154496259371451 1 1 2.00117824522248 -2.90882838659141 8.3150654352623e-08 3.5576269635324 1.17592329800271 3.02539032058892 0.00290498456198804 -20.0535604108177 5.14735866614285 -3.89589335258909 0.000144828647324574 ZNF222 other 0.000832920104650225 1 1 3.02539032058892 -3.89589335258909 6.22374128377646e-06 196.853263935712 43.3433138021903 4.54172158672752 1.21763411889164e-05 6.47467078557357 115.118690090386 0.0562434369300932 0.955230423833526 NPR2 other 0.0524039016093978 1 0.122700990160711 4.54172158672752 0.0562434369300932 2.08875359490214e-08 5.08833408742916 0.920466244448109 5.52799640195389 1.3215504110332e-07 -0.0671375021349463 2.56626062927644 -0.0261616070359447 0.979161661975299 ZNF221 other 0.00021835830081107 1 0.00152572994953783 5.52799640195389 -0.0261616070359447 1.21146907971115e-14 9.45073935980212 1.34849264068865 7.00837296003024 6.8276677896965e-11 -16.713519848615 5.90274492568355 -2.83148265070586 0.00524443291806911 ZNF233 other 1.61319222654337e-10 1 8.93758697542207e-07 7.00837296003024 -2.83148265070586 3.16161069826697e-16 19.0813506456701 2.62560377432941 7.26741438758922 1.65068505596923e-11 -38.5879152332085 11.4930322110351 -3.35750518441582 0.000988206807894175 ZNF235 other 4.32223798560078e-12 1 2.19144948030475e-07 7.26741438758922 -3.35750518441582 9.10922535788825e-08 67.9063677543496 13.775669458698 4.92944230100361 2.17304993311964e-06 -26.7914695742803 34.1477018330258 -0.78457606621038 0.433947768590601 GNE other 0.000909556151985142 1 0.023249461234447 4.92944230100361 -0.78457606621038 1.19142158749312e-12 408.671457868578 107.569770304383 3.79912922294234 0.000207672457329218 -796.229743657444 221.409181342417 -3.59619117341862 0.000432812244936715 ARHGAP35 other 1.50941200919503e-08 1 1 3.79912922294234 -3.59619117341862 0.0383612237062922 12.6928298760098 5.19505294724717 2.44325322665588 0.0156638136400093 7.99220548634324 10.668798678326 0.749119533259135 0.454906075184225 PTGIR other 1 1 1 2.44325322665588 0.749119533259135 4.9643063196083e-21 620.91641174155 73.3580145537966 8.46419325166175 1.89008838268934e-14 -253.938269695777 168.284236818844 -1.5089842904843 0.133351705092405 DFFA other 7.05328641889948e-17 1 2.62193060446665e-10 8.46419325166175 -1.5089842904843 0.000641940397350732 31.0886054832983 11.2990191430917 2.75144285442741 0.00666493831565812 -39.2708416508751 31.9606739557538 -1.22872382807827 0.221099594624422 CCDC28B other 1 1 1 2.75144285442741 -1.22872382807827 4.94042376117982e-11 60.4300511142224 11.3974221019315 5.30208064365548 4.02538440363582e-07 -72.2295247895545 32.2390189026852 -2.24043805450725 0.0265318715323077 IQCC other 5.91961575064566e-07 1 0.00451165083959503 5.30208064365548 -2.24043805450725 4.61734063136048e-11 97.416229468558 19.322524312082 5.04158917826514 1.31372050369178e-06 -141.945483785714 54.6561512747025 -2.5970632851972 0.0103384823849753 TMEM234 other 5.5398852895063e-07 1 0.0142472988625373 5.04158917826514 -2.5970632851972 2.03895878571409e-16 457.820081469662 69.2366242801645 6.61239750247069 6.34033525023473e-10 -625.348647389841 194.867615715585 -3.20909477489864 0.0016306480596752 BSDC1 other 2.79375621047776e-12 1 8.05222576779811e-06 6.61239750247069 -3.20909477489864 7.31597513827369e-11 76.988665256664 12.8507312507273 5.99099489006172 1.50082420836644e-08 -40.5635379364583 36.1685940795993 -1.12151270926337 0.263873867181343 ZBTB8A other 8.70966840211483e-07 1 0.000181239531402331 5.99099489006172 -1.12151270926337 4.62206980461397e-06 113.873621133963 41.3116489846235 2.75645305701421 0.00669038203005894 -207.671822121291 93.0117139011424 -2.23274911740704 0.0272896217463248 ATAD3B other 0.0394170112937479 1 1 2.75645305701421 -2.23274911740704 4.59032560981912e-06 331.693988182361 163.166040913388 2.03286165629545 0.0441026770573092 -1068.82265300591 366.91930463015 -2.91296380299006 0.00421560155465329 SSU72 essential 0.0391738387541964 1 1 2.03286165629545 -2.91296380299006 7.75566779805726e-08 229.069320557952 63.4393923608832 3.61083724218008 0.000442756960442447 -321.43603663217 140.05867364875 -2.29500985735658 0.0234269148494283 UBE2J2 other 0.000778669046924949 1 1 3.61083724218008 -2.29500985735658 2.11674463225775e-09 488.642270310906 89.5221385750932 5.45834000492539 1.89818123867458e-07 -290.004635205315 251.234229404443 -1.1543197592652 0.250168913007601 ZNF362 other 2.35000989073256e-05 1 0.00217038042830052 5.45834000492539 -1.1543197592652 0.0469537039707428 15.6409532026663 7.02232153494927 2.22731943059331 0.0274250878820709 0.267559498812673 19.764439247738 0.0135374191728356 0.989217141459333 FNDC5 other 1 1 1 2.22731943059331 0.0135374191728356 4.41123597421052e-12 556.403713514557 72.2304661658812 7.70317212458168 1.51041877431375e-12 302.542551478708 481.396123390501 0.628469023281458 0.530627720842793 CPAMD8 other 5.48845979911273e-08 1 2.04540910417569e-08 7.70317212458168 0.628469023281458 7.64666978070971e-37 1714.15145983154 101.887007821292 16.8240435801013 8.55348602967141e-37 -44.6452841209901 987.974958328911 -0.0451886798796039 0.964015082869 NR2F6 other 1.11274338648888e-32 1 1.24513096133927e-32 16.8240435801013 -0.0451886798796039 2.27678117899101e-15 34.1920157187218 3.83134160737923 8.92429316479309 1.20113454751822e-15 -7.52853253997961 38.6016482149545 -0.195031375294048 0.845623798475536 ANKLE1 other 3.07206084481256e-11 1 1.68351018180154e-11 8.92429316479309 -0.195031375294048 5.84638339517291e-05 172.168657831677 38.336352276641 4.49100260215895 1.39413346220966e-05 -13.4266761715809 166.436666765885 -0.0806713834906779 0.935809415522906 KALRN other 0.441460410169506 1 0.139427287555588 4.49100260215895 -0.0806713834906779 0.000454202578709227 193.002799771385 48.1007223862349 4.01247195877077 9.40153849944904e-05 327.357980567727 157.0664680719 2.08420030440789 0.0388150011418151 CILP2 other 1 1 0.862685172709444 4.01247195877077 2.08420030440789 0.19563317904612 24.7875602712871 14.3465167076533 1.72777551348502 0.0860462469319058 -8.31666931595392 44.6364628979754 -0.186320079504578 0.852440572786273 FAM86C2P other 1 1 1 1.72777551348502 -0.186320079504578 0.37871702734929 -41.7778434781735 40.061795248072 -1.0428350307188 0.29865899267824 33.0538765609786 78.099444400013 0.423228062823109 0.67271932672025 ABCG1 other 1 1 1 -1.0428350307188 0.423228062823109 0.922766198371136 -44.2959134633531 154.257207236347 -0.287156200069697 0.774378737535859 41.5271987056743 300.720477084365 0.138092354429273 0.890347826175024 TFF3 other 1 1 1 -0.287156200069697 0.138092354429273 0.189556661009039 7.10162621059967 4.21832151453359 1.68351942499691 0.0943006047274775 11.1141115223677 8.22350981891032 1.35150462115462 0.178515757053992 TFF2 other 1 1 1 1.68351942499691 1.35150462115462 0.0396124964930801 -7.70541005014828 182.503292402854 -0.0422206632477594 0.96637748123039 -839.820595983667 355.785497119528 -2.36046888583973 0.0195046381049932 TMPRSS3 other 1 1 1 -0.0422206632477594 -2.36046888583973 0.410115783057022 -3.7168612097316 3.15207978915927 -1.17917738710636 0.240146102799276 0.595276616837781 6.14489886719933 0.096873297625009 0.922952972088676 UBASH3A other 1 1 1 -1.17917738710636 0.096873297625009 0.537030733716797 3.21018199568711 73.967577760369 0.0433998529205195 0.965439016116155 -144.364902233618 144.197899543146 -1.00115814925877 0.318320854755254 RSPH1 other 1 1 1 0.0433998529205195 -1.00115814925877 0.0360915955358807 6.0902333625818 47.9818917656181 0.126927745832352 0.899164244197398 -217.521616851203 93.8676322736239 -2.31732293211709 0.021811915234685 SLC37A1 other 1 1 1 0.126927745832352 -2.31732293211709 0.132825930591345 73.6361296263358 53.2819455115408 1.38200902612286 0.168996554236841 -76.9533259388698 104.038277573728 -0.739663590492793 0.460644976377432 PDE9A other 1 1 1 1.38200902612286 -0.739663590492793 2.61243248088434e-06 49.2936159971537 15.1281962239783 3.2583934837534 0.00138232801840937 -69.8756736111838 29.5393019686036 -2.36551539658766 0.0192668327234139 WDR4 essential 0.022882296100066 1 1 3.2583934837534 -2.36551539658766 0.00032439471077702 39.3625466949887 67.7957701106889 0.580604757947615 0.562366671113455 -454.104816516161 132.377958075363 -3.43036577326294 0.000776264557213969 NDUFV3 other 1 1 1 0.580604757947615 -3.43036577326294 0.0510396696004597 100.099867108939 43.0606838807472 2.324623254618 0.0214156731338349 22.121830757479 84.0802515578075 0.263103765124556 0.792826906450953 PKNOX1 other 1 1 1 2.324623254618 0.263103765124556 0.0156447612593455 265.920777072513 138.369832070201 1.92181180748706 0.0565004255383369 -304.976400589858 269.486479823646 -1.13169462449261 0.259545098621806 CBS other 1 1 1 1.92181180748706 -1.13169462449261 8.29755918602409e-06 173.870139281109 48.2924680766996 3.60035728563227 0.00043041986734963 -145.951243619391 92.7310924474957 -1.57391916526842 0.117599053570332 U2AF1 essential 0.0691269655787667 1 1 3.60035728563227 -1.57391916526842 0.000254181170967362 7.22239917059908 5.44631616927363 1.32610721561586 0.186780461545373 -30.7558237095386 10.3402498785823 -2.97437915627581 0.00341245366274423 HSF2BP other 1 1 1 1.32610721561586 -2.97437915627581 1.49629748876928e-11 493.953052986238 75.9407497159086 6.50445320640233 1.06308502323171e-09 -100.733034550714 143.997173077542 -0.699548695282159 0.485278365633068 RRP1B other 1.82832590152718e-07 1 1.3401249802859e-05 6.50445320640233 -0.699548695282159 0.0279144717332663 179.127093862244 387.24082324707 0.462572856756779 0.644332071231992 -1592.80362989098 734.277499977288 -2.16921208935347 0.0316208430937827 CSTB other 1 1 1 0.462572856756779 -2.16921208935347 7.26768840278473e-09 191.689377324307 47.2977668680163 4.05282088389528 8.05106137181574e-05 -243.936524585996 89.6849813486661 -2.71992613387128 0.00729047233696983 RRP1 essential 7.81131149531303e-05 1 0.74407909198321 4.05282088389528 -2.71992613387128 0.000134091120348306 303.719398620515 133.941594526252 2.2675510150134 0.0247660174175183 -580.135564667366 253.97709453003 -2.28420427338486 0.0237439776529512 AGPAT3 other 0.966394704350244 1 1 2.2675510150134 -2.28420427338486 3.10117339311432e-06 225.65071770335 55.7521270412391 4.04739208490537 8.22133123332852e-05 -110.42957145829 106.177529441294 -1.04004653375691 0.299969809480443 TRAPPC10 other 0.0269460956127703 1 0.759075512773223 4.04739208490537 -1.04004653375691 2.29308777855811e-06 152.144016947054 49.6350120403618 3.06525596938175 0.00257426532400582 -204.902799290205 88.4804598239156 -2.31579717937701 0.0219062209166932 C21orf2 other 0.0202250342068826 1 1 3.06525596938175 -2.31579717937701 0.00737217388968321 40.1689256960069 17.2508063765758 2.32852452338406 0.0211932424237341 -23.5184065710645 30.8415119908808 -0.76255686096124 0.446901757390752 LRRC3 other 1 1 1 2.32852452338406 -0.76255686096124 0.1797417961075 -367.924156829449 197.724691728397 -1.86079014013508 0.064692952978224 -337.482154227962 349.929467667723 -0.964429079029207 0.3363527167345 ITGB2 other 1 1 1 -1.86079014013508 -0.964429079029207 0.000241476110212377 3.57699424342108 24.663431054518 0.145032304528685 0.884878773374984 -158.327044252312 43.7529357960801 -3.6186610423179 0.000403368252572261 FAM207A other 1 1 1 0.145032304528685 -3.6186610423179 4.24304623152707e-07 661.715020790021 144.157414477578 4.59022536709649 9.01709752222043e-06 -67.2670824670841 199.245077205678 -0.337609758848121 0.736108250620204 RALGDS other 0.00400034398708372 1 0.0918842237514262 4.59022536709649 -0.337609758848121 0.157741740913253 8.78545276547611 5.66206796160021 1.55163322394901 0.123007686386184 -2.28589760974755 10.1321959983431 -0.225607322452247 0.821835854041287 FTCD other 1 1 1 1.55163322394901 -0.225607322452247 0.000444719076986618 221.592264670765 62.8609796407779 3.52511631121667 0.000572473264886911 5.88671850452965 112.488894638454 0.0523315525808116 0.958339108612611 SPATC1L other 1 1 1 3.52511631121667 0.0523315525808116 2.86532655701604e-05 328.71157586405 88.6886061304257 3.70635632023177 0.000302016194679214 -121.931638545232 158.8500441776 -0.767589579068097 0.444023709926498 LSS other 0.225357933709312 1 1 3.70635632023177 -0.767589579068097 4.4012000687983e-07 408.995697680269 91.4349926514832 4.47307628972216 1.48369120393871e-05 -57.8263850450356 124.423271558258 -0.464755381536161 0.642758841432923 VAV2 other 0.00414328974476672 1 0.148057545241044 4.47307628972216 -0.464755381536161 4.60568432543812e-10 517.052169317494 96.1555395855251 5.3772478584825 3.17445603775041e-07 -263.557605194283 173.301157727433 -1.52080695045791 0.130612951241931 MCM3AP essential 5.28870731090059e-06 1 0.00357856429135603 5.3772478584825 -1.52080695045791 0.00418582881278433 -9.9628650904032 52.617951122976 -0.189343463167513 0.85010386094257 -291.456306273333 94.9599641393612 -3.06925459497434 0.00258764797304358 C21orf58 other 1 1 1 -0.189343463167513 -3.06925459497434 9.03054720670615e-09 374.073865634892 78.4644231453602 4.76743281400154 4.73579249538751e-06 -241.473165855193 141.785067455834 -1.70309307029396 0.0908348838841614 PCNT other 9.65455801868955e-05 1 0.0494795599918087 4.76743281400154 -1.70309307029396 1.48186420553041e-06 213.125923320436 57.2448263292217 3.72306000361891 0.000287309911884458 -183.023677731085 103.441295267665 -1.76934827872652 0.0790770938774265 DIP2A other 0.0133115861582796 1 1 3.72306000361891 -1.76934827872652 0.648709015062746 -9.51776292648609 17.4659219648197 -0.544933324771347 0.58669187435318 -29.1334579854491 31.5608886765483 -0.923087378306208 0.357596460698749 S100B other 1 1 1 -0.544933324771347 -0.923087378306208 8.36275510378464e-16 614.938023214913 83.1297030150562 7.39733213173559 1.29304746351547e-11 -274.422189310772 150.215219549093 -1.82686008870816 0.069913462717988 PRMT2 other 1.13649841860433e-11 1 1.72052895495369e-07 7.39733213173559 -1.82686008870816 0.613967500626469 -0.480380942908285 2.11433998540094 -0.227201370747 0.820562744742351 -3.76047841655061 4.07266196529182 -0.923346560210076 0.357243508741602 CLDND2 other 1 1 1 -0.227201370747 -0.923346560210076 0.000309606314790237 44.1085113321376 11.7965888972241 3.73909031809329 0.000259389807941301 6.80436854845791 36.7173677610435 0.185317438677541 0.85322233654014 ZNF208 other 1 1 1 3.73909031809329 0.185317438677541 0.0128585602483136 66.0427809619657 23.9614519889136 2.75620947313719 0.00654007772614194 16.9383921010322 32.249094822378 0.525236202576404 0.600159964832657 ADAMTS13 other 1 1 1 2.75620947313719 0.525236202576404 1.37784993193966e-06 320.241442580296 62.3786804683085 5.13382841983961 8.29732203955347e-07 111.070650106162 83.9538431247006 1.32299661304585 0.187760156958127 CACFD1 other 0.0124144278867763 1 0.00910714067061389 5.13382841983961 1.32299661304585 0.208666542460845 54.9648406337829 32.0283939768011 1.71612852875468 0.0881109674987557 23.3414591489831 43.1061821647633 0.541487507749256 0.58893918061771 SLC2A6 other 1 1 1 1.71612852875468 0.541487507749256 5.28956353290526e-10 54.2598768886401 13.6345329250419 3.97959190732407 0.000105753591136862 -109.785027386342 35.0005557778834 -3.13666525991895 0.00204526257301658 ZNF761 other 6.05707920152982e-06 1 0.964790011941592 3.97959190732407 -3.13666525991895 0.0374720130467123 -48.0657371357896 59.5535324583149 -0.807101361609973 0.420903254806788 -204.032313379342 81.2476396924325 -2.5112398852658 0.0131047681321919 C9orf116 other 1 1 1 -0.807101361609973 -2.5112398852658 0.148646452216398 18.2662937298832 13.4573668643847 1.3573453049144 0.17673775664876 -8.64630975304653 18.3596043605261 -0.470942052086724 0.638375503824572 LCN1 other 1 1 1 1.3573453049144 -0.470942052086724 3.9237717925415e-08 111.21551676871 19.9180879123005 5.58364423625365 1.03851919812524e-07 11.281269609187 62.8486122308855 0.179499104415277 0.857781777994625 ZNF714 other 0.000402225846453429 1 0.00120561693710359 5.58364423625365 0.179499104415277 0.00132287966962435 317.309047397461 85.0121425644934 3.73251441294681 0.000283971644485925 264.968126925036 126.764312967665 2.09024228287834 0.0385747354755963 GPSM1 other 1 1 1 3.73251441294681 2.09024228287834 4.27286616847606e-32 142.850647681925 10.8962811313826 13.110036897864 6.75339992888612e-27 -47.2754716586925 39.133675149993 -1.20805090443188 0.228867622411604 C19orf47 other 6.20377439001039e-28 1 9.77824775703422e-23 13.110036897864 -1.20805090443188 0.000690593997508533 71.8697828912518 114.267140140194 0.628962821709505 0.530299235448592 -460.778931786455 159.635402495564 -2.88644576693606 0.00445263358612315 CFAP157 other 1 1 1 0.628962821709505 -2.88644576693606 0.00306181243131911 100.864296375866 43.571712895024 2.31490317167184 0.0219303125498318 -50.8428188682309 60.4238748869371 -0.841435921866415 0.401400057291126 TOR2A other 1 1 1 2.31490317167184 -0.841435921866415 0.000461770904360855 215.780443887736 115.918564773522 1.86148305329108 0.0645944895676215 -308.25216268055 159.147393349411 -1.93689733895784 0.0546004106457473 ST6GALNAC6 other 1 1 1 1.86148305329108 -1.93689733895784 1.49036467343508e-22 681.980705678325 73.2253305486103 9.31345342614186 1.26917780564962e-16 -536.871927558991 245.766717584961 -2.1844777553063 0.030449267355206 SHKBP1 other 2.13032726420811e-18 1 1.79030221264935e-12 9.31345342614186 -2.1844777553063 1.30272464513999e-08 108.433077901103 35.8547702858451 3.02423016621337 0.00291271571881625 -217.972057088531 73.9571402546786 -2.9472753589163 0.00369510541670572 RDH13 other 0.000138034450352937 1 1 3.02423016621337 -2.9472753589163 2.48822241456279e-15 739.695917334685 109.376294921259 6.76285403402263 2.64591732662512e-10 -185.550773655756 148.66647439531 -1.24810098854143 0.213888379601978 ZER1 other 3.35536792603792e-11 1 3.40026835644595e-06 6.76285403402263 -1.24810098854143 0.000100333390222521 14.8474726357559 121.148025385908 0.122556455942722 0.902618127490651 -586.56714559642 164.666848763185 -3.56214471827288 0.000489850500075874 ZDHHC12 other 0.73584508389197 1 1 0.122556455942722 -3.56214471827288 4.78545178325076e-05 130.144045114384 33.8688350585181 3.84258994705673 0.000177587511764314 4.64658845774885 46.035206290824 0.100935541124642 0.919732920571999 PKN3 other 0.365134504943572 1 1 3.84258994705673 0.100935541124642 0.0500886333686678 5.35242614298956 8.28950213228681 0.645687287073898 0.519449086641334 -49.9250235475287 27.814736728901 -1.79491267647534 0.0746416691886035 SPTBN4 other 1 1 1 0.645687287073898 -1.79491267647534 0.0123810156987813 35.4405049637456 27.3094310361105 1.29773867924541 0.196343087826814 -82.4518140476333 54.102685838477 -1.5239874466453 0.129589729981883 BRSK1 other 1 1 1 1.29773867924541 -1.5239874466453 0.685914100144857 2.84528752649825 7.60194933749693 0.374283936945455 0.708718152054551 -6.61759143981955 15.0860676659867 -0.438655823792947 0.661537912681899 COX6B2 other 1 1 1 0.374283936945455 -0.438655823792947 0.913892688636706 -7.43980382904713 26.5187230417556 -0.280549097983814 0.779442827937481 -22.0694894206347 52.4543450225578 -0.420737107881983 0.674549235429212 TMEM190 other 1 1 1 -0.280549097983814 -0.420737107881983 0.763056961759279 -5.53152709359602 10.2981032358964 -0.537140380795039 0.591931085397482 -10.4010098522167 14.3782138031847 -0.723386784658393 0.470518661650632 PLPP7 other 1 1 1 -0.537140380795039 -0.723386784658393 0.0217282817156095 56.8593205574913 28.4649887823931 1.99751775741648 0.0474854714406952 -16.4003339140535 39.6231654219727 -0.413907716342089 0.679503001672285 MED27 other 1 1 1 1.99751775741648 -0.413907716342089 2.95996293624115e-18 171.457700763411 25.3318508072156 6.76846323106295 2.61053874771978e-10 -207.349892191428 67.0718117803524 -3.0914610279272 0.00236730523397088 DEDD2 other 4.13714019598425e-14 1 3.35558650631901e-06 6.76846323106295 -3.0914610279272 2.71315981027736e-14 387.599036010211 52.5246102664744 7.37937957166736 9.67146862458703e-12 -137.089627342984 140.516631186409 -0.97561140048342 0.330807189181843 SIK3 other 3.58869648105387e-10 1 1.28949691171619e-07 7.37937957166736 -0.97561140048342 3.0219912659052e-12 56.6467831470632 9.82855308150441 5.76349160220363 4.35760032079659e-08 -80.7268906011521 27.3870562475759 -2.94762934254014 0.00370097971254244 MPZL3 other 3.78111547190059e-08 1 0.000515721997966277 5.76349160220363 -2.94762934254014 0.745018696683581 -2.86678708581556 8.58081321856971 -0.334092703429501 0.738764129737394 12.3719351582887 23.9102553873516 0.517432162804644 0.605596946274296 JAML other 1 1 1 -0.334092703429501 0.517432162804644 2.28786835238275e-12 73.0494330645413 12.2274384068984 5.97422212516144 1.91404882569774e-08 -220.583742700899 49.2164628865854 -4.48190970588871 1.55599133524521e-05 NEK8 other 2.87356265059273e-08 0.22552538413044 0.000230240933243182 5.97422212516144 -4.48190970588871 0.00583197215968261 36.3107177063059 21.1963112920397 1.71306776948225 0.0889787889438146 -211.914604381005 85.3169268428806 -2.48385182428413 0.0142120068860903 TLCD1 other 1 1 1 1.71306776948225 -2.48385182428413 0.0188329750627289 527.395469432314 278.052104375337 1.89675050515134 0.0597704510019209 -818.166757641923 753.108914951338 -1.08638570251793 0.279039596886858 PCSK7 other 1 1 1 1.89675050515134 -1.08638570251793 8.20687523346497e-08 370.897404730314 80.0997877150008 4.63044179405301 7.67151332161387e-06 25.2141445445525 145.244648841653 0.173597752107488 0.862408106179412 SAFB other 0.00082232889839319 1 0.078656026086507 4.63044179405301 0.173597752107488 0.613762451323249 4.50704614664594 5.59328747586999 0.805795547983148 0.421603232478462 13.0109371147313 15.500035546369 0.839413372686052 0.402538563177244 CD3G other 1 1 1 0.805795547983148 0.839413372686052 1.79158850316099e-11 504.333815771045 75.5361890759957 6.67671776853401 4.31255028371672e-10 -227.222624169979 213.836105504728 -1.0626017698632 0.289647893432521 CXCR5 other 2.18340890880229e-07 1 5.50281416202253e-06 6.67671776853401 -1.0626017698632 4.30322092088523e-15 264.140247789572 34.1787557752199 7.72819963156992 1.97137935657203e-12 -209.010560159651 96.0416345944097 -2.17624950931246 0.0312260995694634 VPS11 other 5.77965601884096e-11 1 2.66451633834275e-08 7.72819963156992 -2.17624950931246 9.3946059570696e-08 137.995830612347 26.6260939655204 5.18272904734153 7.10220763127109e-07 -77.0791346427557 74.8167445628931 -1.03023908742729 0.304589896114828 NLRX1 other 0.000936642213919839 1 0.00783018391347638 5.18272904734153 -1.03023908742729 6.88097354010053e-07 97.1196572372496 24.2888359624529 3.99853074010558 9.83717255061688e-05 -103.146465689311 53.5181125932996 -1.92731882144559 0.0557688242417132 ANO10 other 0.00636421242723898 1 0.900888262185494 3.99853074010558 -1.92731882144559 0.781515870020442 -2.79068044651353 10.0083194819247 -0.27883606748901 0.780742304090423 10.5203320526694 21.96017706112 0.479064081468423 0.632568202833757 CCR5 other 1 1 1 -0.27883606748901 0.479064081468423 0.00205231202163041 354.677397461895 142.577515990558 2.4876110023223 0.0140784020807997 -457.445040448312 317.365180655605 -1.44138383266663 0.151791873089412 NBEAL2 other 1 1 1 2.4876110023223 -1.44138383266663 2.30868891934508e-08 126.168499052995 25.9751245968139 4.85728176520356 3.14347543514591e-06 -103.180753529576 57.5563037694191 -1.79269249017339 0.07518136378447 CCDC12 other 0.00024044995094979 1 0.033242252726668 4.85728176520356 -1.79269249017339 0.387949343215585 21.0909200667054 15.8631132226023 1.32955743117652 0.185826467481091 6.48428574662513 35.1498665565891 0.184475401526371 0.853907474941182 PTH1R other 1 1 1 1.32955743117652 0.184475401526371 0.015006604744861 84.1181430152289 41.3057284152442 2.03647644630773 0.0434498983109668 -181.663487379459 136.786660559318 -1.32807897083415 0.18615596157322 PPP1R35 other 1 1 1 2.03647644630773 -1.32807897083415 0.4456803280865 29.897942521228 28.97491094092 1.03185623528542 0.303726383183402 -41.2218811234486 95.3722990573235 -0.432220692285841 0.666174078191776 AZGP1 other 1 1 1 1.03185623528542 -0.432220692285841 0.242777853230548 65.1276941657377 40.5823625980966 1.60482756538163 0.110621203966391 77.030982905983 66.3967231833317 1.16016241785439 0.247813726465921 FGFR4 other 1 1 1 1.60482756538163 1.16016241785439 2.68107322484812e-13 1212.85641677255 163.328940903146 7.42585123044286 8.19903513982598e-12 -1044.11080050826 981.80918949114 -1.06345592573788 0.289307314542137 NACC1 other 3.46099742595644e-09 1 1.09457119116677e-07 7.42585123044286 -1.06345592573788 0.260442681908934 -11.4988179379747 8.39224069824698 -1.37017256194483 0.172666753564198 3.54050336753075 13.6897429076878 0.258624533083269 0.79627714965562 HK3 other 1 1 1 -1.37017256194483 0.258624533083269 0.0857269282480445 113.078369753143 50.8296765135152 2.22465255554156 0.0278427845700853 96.3372710491765 219.600429613305 0.438693454374461 0.661617515268086 LY6K other 1 1 1 2.22465255554156 0.438693454374461 5.33258614190047e-05 430.951501179887 144.790757828904 2.97637437390261 0.00340824110325695 -1918.63177709203 870.371752879382 -2.20438194454815 0.0290415439767416 IER2 other 0.404956591615922 1 1 2.97637437390261 -2.20438194454815 1.38228329860148e-11 91.5747001447691 13.7129803927711 6.67795749150515 4.15138534215115e-10 -90.3305296623581 45.8780305828381 -1.96892779648106 0.0507561626889674 ZNF394 other 1.69039424585974e-07 1 5.29965852779016e-06 6.67795749150515 -1.96892779648106 1.84782172169886e-11 139.572577739639 20.1437145828245 6.92884011862662 1.08783011376006e-10 -89.1958115251837 67.3926402002266 -1.32352451632966 0.187622481590172 CPSF4 essential 2.25101642137355e-07 1 1.41602845908147e-06 6.92884011862662 -1.32352451632966 0.0280585029931916 5327.58079011421 1967.3530628172 2.70799425421142 0.0077254126222617 5882.7878986457 8550.60055638091 0.687997042997835 0.49273964828666 LY6E other 1 1 1 2.70799425421142 0.687997042997835 0.00101781699189795 845.373255813952 235.605388506441 3.58808964927744 0.000507723928214658 -188.741618217055 906.349496330383 -0.208243750320632 0.83544205586442 VPS28 essential 1 1 1 3.58808964927744 -0.208243750320632 4.97547568835205e-05 322.377511757162 75.4658401358322 4.2718336028183 4.24318296602388e-05 -150.522873022659 291.12060038704 -0.517046450242755 0.606200931039473 TONSL essential 0.378882473668009 1 0.404163177513774 4.2718336028183 -0.517046450242755 0.0673769667692847 15.5511406419752 6.71802562758002 2.31483794556126 0.0219601248470082 47.4194347992665 46.8398182755468 1.01237444006102 0.312967867775634 PTGER1 other 1 1 1 2.31483794556126 1.01237444006102 0.0106771632145581 122.779908972692 54.5565873260525 2.2505056674258 0.0259871204130935 -67.5263759274841 81.8571641429265 -0.824929334341217 0.41082514697964 MUM1 other 1 1 1 2.2505056674258 -0.824929334341217 0.00493726336631593 154.996504052122 52.0522079629009 2.97771237989736 0.0036135751962739 -104.792534032522 192.688167844909 -0.543845194048799 0.587711985614929 RECQL4 ts 1 1 1 2.97771237989736 -0.543845194048799 4.50805520425526e-05 182.267916732878 47.1709218628812 3.86398886294196 0.000194323537035084 -239.15701308332 174.618500636748 -1.36959722029012 0.173762711031324 LRRC14 other 0.34491130367757 1 1 3.86398886294196 -1.36959722029012 3.64980328635885e-31 103.423596499341 7.10881655286381 14.5486376994321 1.35775458113428e-30 -2.90530821521879 52.7740462119069 -0.0550518374799787 0.956169460240492 ZNF333 other 5.29549958817805e-27 1 1.97091654997452e-26 14.5486376994321 -0.0550518374799787 0.638639462733586 53.9281579168617 57.3158432123277 0.94089443501832 0.348223013018586 72.4497772012635 185.230517616418 0.391133049421669 0.696236019602215 COL26A1 other 1 1 1 0.94089443501832 0.391133049421669 0.000111134320710267 530.352559948152 136.561936698393 3.88360455900296 0.000180237004530034 -488.759019226616 527.108511362002 -0.927245545634817 0.355925562546958 PPP1R16A other 0.811058272543531 1 1 3.88360455900296 -0.927245545634817 0.135148611560168 79.4843378699503 39.9107872485309 1.99155023866075 0.049017361162268 42.3308489954632 154.049628779951 0.274787088620185 0.784019764823815 FOXH1 other 1 1 1 1.99155023866075 0.274787088620185 2.62896495704216e-06 226.023310838061 46.9807591554209 4.81097612940513 3.56796745826802e-06 -81.9040679697791 145.786351688008 -0.561808886918709 0.575068298433119 ORAI2 other 0.0230192171638612 1 0.0375992410752283 4.81097612940513 -0.561808886918709 2.45626590563412e-15 68.4048476863927 9.13781372940733 7.4859096182112 5.23528010923716e-12 -76.2422185178214 28.3556194059748 -2.68878691825566 0.00796642104460194 ALKBH4 other 3.31252020033817e-11 1 7.02155768250888e-08 7.4859096182112 -2.68878691825566 4.03171382999151e-11 154.982364652816 21.3171607895162 7.27030987771302 1.76399029927788e-11 34.9113935726259 66.2192444559611 0.527209180041969 0.598816971453093 SH2B2 other 4.85015173747979e-07 1 2.34063872811182e-07 7.27030987771302 0.527209180041969 0.0134190650648294 576.51084325446 399.788497767181 1.44203959462134 0.151403983311304 -1039.04755380027 646.515594142979 -1.60715002578961 0.110152824783188 MRNIP other 1 1 1 1.44203959462134 -1.60715002578961 0.0238707858954133 1293.60618485402 917.008882392742 1.41068010320536 0.160437392439951 -2110.83122430886 1482.93546649205 -1.42341408106053 0.156720824037289 SQSTM1 other 1 1 1 1.41068010320536 -1.42341408106053 5.77722676552924e-05 1082.67545764815 329.324658967025 3.28756267764497 0.00126425551722071 -648.275405392167 523.597721299737 -1.23811731606268 0.217646268653105 MGAT4B other 0.436700571206355 1 1 3.28756267764497 -1.23811731606268 0.000430171497808898 350.353688933201 104.51629334571 3.35214422285654 0.00100905684225685 -76.8103643614609 170.819234683491 -0.449658754787083 0.653588768434167 MAML1 other 1 1 1 3.35214422285654 -0.449658754787083 1.58053253362712e-07 16.9041251948675 3.29497257736189 5.1302779607355 8.64766837881334e-07 -11.5521045688931 10.273416123159 -1.12446575028257 0.262576538110379 FBXL13 other 0.00154781551018104 1 0.00948389791104459 5.1302779607355 -1.12446575028257 6.15603871260691e-06 153.279999735831 35.8059869410821 4.2808483393587 3.27234087241224e-05 -141.19889973451 112.163066584127 -1.25887160573133 0.20999407691609 NAPEPLD other 0.0518646261537132 1 0.315682723961609 4.2808483393587 -1.25887160573133 0.183536395386142 -131.429956349609 104.480763811508 -1.25793449009158 0.210409976706443 -308.704263526545 172.973615779945 -1.78468989119864 0.0763740834433373 SCGB3A1 other 1 1 1 -1.25793449009158 -1.78468989119864 0.000646437225815113 73.8493458940324 53.3374825100128 1.38456752022687 0.168187573382624 -507.771346925221 167.047882181826 -3.03967545288919 0.00278364861648341 PSMC2 essential 1 1 1 1.38456752022687 -3.03967545288919 0.386847555241622 -2.60913407554723 16.3396411297555 -0.159681235030054 0.873348441218373 -31.1806045839174 24.4522807455086 -1.27516140144287 0.204236819564683 CELF5 other 1 1 1 -0.159681235030054 -1.27516140144287 0.000344157827793442 240.847932980574 125.592701664737 1.91769051694983 0.0570634508049049 -417.333695388928 187.949537955305 -2.22045608586795 0.0278973229845164 MFSD12 other 1 1 1 1.91769051694983 -2.22045608586795 0.0021598489346434 34.6378028967472 9.77225562318507 3.54450438387711 0.000535208683675405 22.0795049949877 15.0590437176973 1.46619569003841 0.144837506110697 USP41 other 1 1 1 3.54450438387711 1.46619569003841 1.12922986385171e-13 46.1651232225089 5.4743844670389 8.4329340586997 3.45538917657816e-14 23.4260816760285 9.84620569625493 2.37919889129869 0.0186799946292134 TUBA3FP other 1.47082189766686e-09 1 4.77292906960741e-10 8.4329340586997 2.37919889129869 4.87321473584547e-12 390.373697488209 64.8163803165094 6.02276300499885 1.26713336725319e-08 -187.715622829147 119.951229044567 -1.56493288417581 0.11970590168269 YDJC other 6.05204538044649e-08 1 0.000153487864775378 6.02276300499885 -1.56493288417581 2.23917960166903e-11 1214.92282915045 160.07953933285 7.58949478624052 4.7218154178629e-12 -167.624739967789 670.875083568481 -0.249859838401165 0.803075548380491 DVL3 other 2.71925970826688e-07 1 6.33856501693915e-08 7.58949478624052 -0.249859838401165 0.000123233959607376 1686.03964921785 410.280012396742 4.1094852253915 6.86836602649231e-05 -1725.00865951107 1719.31070900258 -1.00331409004705 0.317517674410851 AP2M1 essential 0.893939142991909 1 0.639238826085639 4.1094852253915 -1.00331409004705 5.8309434775248e-11 314.284034991799 41.8726905328864 7.50570433836736 7.63540964267892e-12 102.681387289744 170.919402519589 0.600759105028906 0.549015240647476 ABCF3 other 6.96914364433765e-07 1 1.02031979055118e-07 7.50570433836736 0.600759105028906 7.52462100608728e-10 240.125938427516 34.708125043155 6.91843590309044 1.33219169984058e-10 74.9766047837977 129.097668905066 0.580774272840923 0.562288001263609 PCYT1A essential 8.54947438711637e-06 1 1.72918482639307e-06 6.91843590309044 0.580774272840923 2.81742282063168e-09 84.8280169732403 14.7254229254756 5.76065063818876 4.41835696778854e-08 -24.3693500503229 54.7465444810749 -0.445130378205824 0.656850579828651 FBXO27 other 3.10508169061817e-05 1 0.000522778789121168 5.76065063818876 -0.445130378205824 1.28880811980899e-09 714.442934590287 114.883471099604 6.21884878435527 4.4473567268122e-09 -234.824622182589 562.419187913517 -0.417525979250014 0.676871501813432 DMKN other 1.4466871144856e-05 1 5.48759346521358e-05 6.21884878435527 -0.417525979250014 5.10762296073417e-21 86.2732375736506 8.7838743680632 9.82177498887355 5.5666438548725e-18 -50.5015369647677 37.936705709237 -1.33120512233806 0.185088858603832 U2AF1L4 other 7.25639994031503e-17 1 7.90908758900284e-14 9.82177498887355 -1.33120512233806 5.30703046858196e-07 304.170850196865 55.4723410623207 5.48328850688207 1.87363405914884e-07 -33.2805862668433 214.511000969576 -0.155146291408913 0.876927864683644 BDH1 other 0.00495517434851498 1 0.00214343736366627 5.48328850688207 -0.155146291408913 6.16385797302016e-14 106.772319220859 14.6690365155205 7.27875475038113 1.68402903671448e-11 -96.5847574370816 64.4237105675603 -1.49921133983418 0.135892894536025 THAP8 other 8.09129636118357e-10 1 2.23554854623848e-07 7.27875475038113 -1.49921133983418 0.0230375336088588 16.2405093444789 5.91614627226851 2.74511626269368 0.00677842531971978 17.0510427268986 24.5308355310786 0.695086097059204 0.488062563965067 COX7A1 other 1 1 1 2.74511626269368 0.695086097059204 1.29229605633997e-12 34.9052075889256 5.54959305141361 6.28968777810373 3.34836374742925e-09 -47.3309314111485 22.2276573531685 -2.12937111001495 0.0348670648360738 ZNF382 other 1.6356591185095e-08 1 4.14962719218907e-05 6.28968777810373 -2.12937111001495 0.160171575209365 47.0338993698535 31.7540524501622 1.48119360335733 0.140666599586768 -13.0252735145166 54.8582187601561 -0.237435225001817 0.812645326728779 LRRC56 other 1 1 1 1.48119360335733 -0.237435225001817 0.223108479940981 -33.3876237033507 28.0416583022258 -1.19064369672818 0.235637490117716 117.27339930845 107.597106012411 1.08993079511752 0.277457265160369 PLXDC1 other 1 1 1 -1.19064369672818 1.08993079511752 1.60589655869477e-21 365.03225 32.3204663314872 11.2941517073465 7.93749366165102e-22 -239.366035714285 196.876364142781 -1.21581905860822 0.225951200385975 PGAP3 other 2.28759964786071e-17 1 1.14188783816512e-17 11.2941517073465 -1.21581905860822 0.600593028641849 2.33240048585334 3.33113944747492 0.700180980901701 0.484884588592835 77.7807907842394 106.221511903632 0.732250834979686 0.465143060075369 IKZF3 other 1 1 1 0.700180980901701 0.732250834979686 0.503804690321952 10.6496112124412 10.6224907931111 1.00255311299942 0.317639078638595 28.313477968705 45.4300389926726 0.623232526242641 0.534047704060629 GRIN2C other 1 1 1 1.00255311299942 0.623232526242641 9.96681266259273e-05 51.5545396055529 29.3741470510041 1.75509911882839 0.081230904040469 -500.640543416398 124.158413934553 -4.0322723813168 8.66565781932878e-05 FDXR essential 0.731065708801176 1 1 1.75509911882839 -4.0322723813168 7.14450641046342e-16 338.233708499685 36.2223362992301 9.33771101084039 1.00307094914301e-16 135.721796858584 168.116733569045 0.807306887168631 0.420726811085122 SAP30BP essential 9.72581657656386e-12 1 1.41593495181027e-12 9.33771101084039 0.807306887168631 1.01424521498586e-07 292.327970224679 49.8703254740677 5.86176182821762 2.63944441592725e-08 254.00948341377 231.925537252176 1.0952199849281 0.275108296987461 ACOX1 other 0.00100876829082494 1 0.000315440002147466 5.86176182821762 1.0952199849281 6.97051539644285e-23 346.867560921082 28.996461472546 11.9624100081831 7.48155623124492e-24 156.938743572546 127.674470699826 1.2292100583015 0.220832142260979 PRPSAP1 other 9.97898984154759e-19 1 1.0793641174817e-19 11.9624100081831 1.2292100583015 0.95090652971821 3.32698412698392 13.3113411092308 0.249936058259135 0.802963532348261 -10.9067460317477 58.6112354445381 -0.186086267402918 0.852617327099808 CYGB other 1 1 1 0.249936058259135 -0.186086267402918 0.000520124554239753 20.673301393514 7.05498580887235 2.9303108402451 0.00389505499754982 -8.04531338898211 13.6816424090509 -0.588037104643215 0.55735770030573 ZNF577 other 1 1 1 2.9303108402451 -0.588037104643215 2.26921414546941e-06 38.2254608211575 12.0863966995755 3.16268460909447 0.00187690815691807 -31.9574227212176 21.0297864596996 -1.51962659166602 0.130616139418823 TMEM143 other 0.020028084047913 1 1 3.16268460909447 -1.51962659166602 0.0183309754361472 190.747196123816 66.8145129430051 2.85487669851801 0.00488735072212067 178.92587960058 117.879231061086 1.51787450588187 0.131057108421886 ALDH16A1 other 1 1 1 2.85487669851801 1.51787450588187 0.386170055786371 -149.261363396902 118.822353249999 -1.25617242306976 0.211101823230283 -325.940845011064 344.40022615472 -0.946401367531728 0.345540368195292 ITGA5 other 1 1 1 -1.25617242306976 -0.946401367531728 0.741336316104724 6.85175675097361 9.54745268188335 0.717652862943754 0.474037808425166 3.07676637993751 16.5237243734637 0.186202959477989 0.852525974970243 SIGLEC11 other 1 1 1 0.717652862943754 0.186202959477989 6.95347364636993e-07 371.950036877042 68.2535590906693 5.44953320870691 2.15272171165989e-07 96.229868296281 197.82928501032 0.486428833280477 0.627407798313726 ZNF385A other 0.00642779103870437 1 0.00245367220694994 5.44953320870691 0.486428833280477 0.439367112772371 3.40244789660634 4.49071392260925 0.757663025354642 0.449788437058981 -3.07329995292507 7.7720541352433 -0.395429560762942 0.693062674643905 SIGLEC16 other 1 1 1 0.757663025354642 -0.395429560762942 4.0912427629905e-06 36.0410493535906 7.7539189347426 4.64810757720244 7.08554875464321e-06 -60.463087037212 33.053996295596 -1.82922169218213 0.0692757969260679 MPP3 other 0.0351560490623774 1 0.0728394411977322 4.64810757720244 -1.82922169218213 0.000586323912503272 22.1503255638388 5.73430982553052 3.86277097641642 0.000163965802433619 -10.9464313799503 24.444652739612 -0.447804740634005 0.654915360269069 NAGS other 1 1 1 3.86277097641642 -0.447804740634005 1.12257461876233e-06 212.199207322827 38.9161368043025 5.45273053155077 1.90378752812838e-07 11.8454174661584 165.894672435213 0.0714032421432003 0.943168287568774 LSM12 essential 0.010197467836837 1 0.00217640990215636 5.45273053155077 0.0714032421432003 1.84342308714241e-05 25.0951239008793 5.19120113141275 4.83416520870765 3.19223980957758e-06 14.1838529176658 20.3555934777443 0.696803703275646 0.486969353309127 ASB16 other 0.148008439666664 1 0.0337419747872351 4.83416520870765 0.696803703275646 5.2674614461537e-08 806.058667947071 255.667790032537 3.1527579905333 0.0019422750495893 -1099.96664170966 460.709271616855 -2.38755047809075 0.018165658404965 EMC10 other 0.000535068733700293 1 1 3.1527579905333 -2.38755047809075 0.0350573708659656 25.8537858689106 31.6586947665245 0.816640927858089 0.415387009002049 -87.3626483178438 57.0484620075514 -1.53137604842493 0.127714905779029 JOSD2 other 1 1 1 0.816640927858089 -1.53137604842493 0.040813853668841 103.26116905572 91.9689098362733 1.12278344105143 0.263288278043494 -196.198730462465 163.939961628434 -1.19677184570254 0.23324661097771 SHANK1 other 1 1 1 1.12278344105143 -1.19677184570254 4.8628042223012e-05 593.650352037945 130.120413819531 4.56231527868717 1.01841274540658e-05 544.998495879816 510.292701943424 1.06801154279537 0.287165225710581 FAM171A2 other 0.370788821950467 1 0.103368893658768 4.56231527868717 1.06801154279537 3.56144704843629e-09 120.396231037236 18.2736094184368 6.58853039267462 6.36438991190141e-10 108.045982434492 71.9941763827528 1.50076003175691 0.135426041192139 DBF4B other 3.90227753097164e-05 1 8.08150231013241e-06 6.58853039267462 1.50076003175691 0.0793490262130813 439.9691016159 252.933168049383 1.73946780095681 0.0839249330570406 -1314.92391952048 1016.83078907471 -1.29315903260269 0.197867781011407 PLCD3 other 1 1 1 1.73946780095681 -1.29315903260269 3.61789546948504e-05 436.37450629919 105.169627418527 4.14924457764425 5.64136812372452e-05 -80.6576094790559 267.594728702932 -0.301417034147176 0.76352538154847 FMNL3 other 0.28038689888509 1 0.530062948905155 4.14924457764425 -0.301417034147176 0.0463921832277851 -236.578142838314 285.12730180338 -0.829728129652961 0.407993714717649 -1813.66478774434 726.022215585776 -2.49808442332721 0.0135510552567244 AQP5 other 1 1 1 -0.829728129652961 -2.49808442332721 0.00228761858306785 116.342880870763 73.6227874708289 1.58025639706811 0.116113303507853 -434.705174135068 187.488375911497 -2.31857133553852 0.0217421878789851 RACGAP1 essential 1 1 1 1.58025639706811 -2.31857133553852 4.50185519186415e-05 76.5373013640838 34.653999031316 2.20861382534578 0.0286885930674542 -256.181165184222 88.2349607488953 -2.90339750831055 0.00423773124158407 LARP4 other 0.344526977833364 1 1 2.20861382534578 -2.90339750831055 0.00399155521458563 33.4318183298134 12.6521304374719 2.64238647356955 0.00908267314680959 -33.2647823000935 32.8999752636225 -1.01108836810812 0.313560099768631 GRASP other 1 1 1 2.64238647356955 -1.01108836810812 3.23503731412766e-36 1451.12629504894 95.7179655997401 15.1604381262871 2.03115722949219e-32 -199.349830618956 383.048449873671 -0.52042980642449 0.603506624608675 RAVER1 other 4.70600878086151e-32 1 2.95208391734394e-28 15.1604381262871 -0.52042980642449 1.26807674862604e-06 20.3055481387099 4.38810209148283 4.62741014574896 7.98619274047878e-06 -19.7953950222931 22.3098810563119 -0.887292718967346 0.376351302839554 SYCE2 other 0.0114634138075794 1 0.0817786136625027 4.62741014574896 -0.887292718967346 7.43097145613189e-08 133.000929022668 25.8049817534866 5.15407956080799 7.81366769495531e-07 -47.4663693794128 90.7529366133468 -0.523028467735908 0.601716038009552 SPC24 essential 0.000747704347915991 1 0.00859034626383386 5.15407956080799 -0.523028467735908 0.75363994969271 -1.98049395628976 8.53579930903127 -0.232022085406145 0.816830907668568 -18.3356051723704 24.579096767353 -0.745983684669998 0.456821880194236 IP6K3 other 1 1 1 -0.232022085406145 -0.745983684669998 8.33890889565774e-13 326.009509403176 53.3968580934309 6.10540621758573 8.09189813166994e-09 -349.673357524666 153.105498703118 -2.28387197381268 0.0237548742910953 LEMD2 other 1.06129293515036e-08 1 9.885062757648e-05 6.10540621758573 -2.28387197381268 2.91876865357564e-11 14.9700403979619 2.05829487041875 7.27303002747915 1.70179113352983e-11 -4.23750992684962 13.4067790091404 -0.316072184374829 0.752378492532851 ADCY10P1 other 3.52966693276902e-07 1 2.25844701330743e-07 7.27303002747915 -0.316072184374829 1.87316372931614e-24 60.6870672389127 6.5158130132381 9.3138135050247 1.52063606950757e-16 -79.1516165951359 23.5312912046836 -3.36367502771721 0.000977871876966708 ZNF653 other 2.6936094427566e-20 1 2.14394479439872e-12 9.3138135050247 -3.36367502771721 8.16332924842936e-12 97.5487515782421 13.5831841250059 7.18158207092694 2.86767508182014e-11 -135.0568553686 75.5733713505035 -1.78709581106574 0.0759148394373218 MED11 essential 1.00637522974637e-07 1 3.78905908560895e-07 7.18158207092694 -1.78709581106574 0.00521767426761101 726.024607694091 220.174806003881 3.29749175607901 0.00121470211438834 548.775477337733 1224.99645318981 0.447981278565141 0.654804563553299 CXCL16 other 1 1 1 3.29749175607901 0.447981278565141 0.439232239682285 5.94825262779625 5.53198872371517 1.07524670147945 0.283924490756485 -13.8441739286676 28.2820752095194 -0.489503469109218 0.625172901029001 SCIMP other 1 1 1 1.07524670147945 -0.489503469109218 7.09249910237385e-06 986.712771727792 204.44376119204 4.82632859997594 3.30328794364573e-06 -352.056473484377 1100.9009048326 -0.319789430582683 0.749558595978216 RNASEK-C17orf49 other 0.0594138649805857 1 0.0348926305487299 4.82632859997594 -0.319789430582683 0.474005688033912 10.675929402929 9.00845096143845 1.18510157280407 0.237791100410041 28.4111278007238 48.5092416455398 0.585684847607509 0.558939116023858 BCL6B other 1 1 1 1.18510157280407 0.585684847607509 0.0260025179104974 36.8618290258439 80.8873404411233 0.455718148536174 0.649265136935592 -968.752485089471 393.965544688697 -2.4589776901809 0.0150939412412051 TNFSF13 other 1 1 1 0.455718148536174 -2.4589776901809 2.96517680978559e-17 1879.15407554672 209.4986746615 8.96976593566993 1.27000260420658e-15 -1711.33675723437 1020.37301541215 -1.67716779196001 0.0956348222958623 SENP3 other 4.10202559865738e-13 1 1.77965464927468e-11 8.96976593566993 -1.67716779196001 1.31516912142643e-08 128.201695371368 20.0170146201718 6.40463614600026 1.88732016966464e-09 135.25672766417 106.751659136922 1.2670222529346 0.207137495728638 FGF11 other 0.000139315865032702 1 2.3614149962844e-05 6.40463614600026 1.2670222529346 7.87463542798015e-16 3023.55038459411 373.472528552773 8.09577720832783 1.98329805889158e-13 -4296.89982107611 1816.57302078285 -2.36538788802686 0.0193166384365449 EIF4A1 essential 1.0705566864339e-11 1 2.71751500029324e-09 8.09577720832783 -2.36538788802686 1.00723531986662e-12 2777.10284152383 536.828406729987 5.17316670785018 7.36424211785039e-07 -13156.3789647515 2777.81299958136 -4.73623637254712 5.05403382193511e-06 RPL26 essential 1.27898740916663e-08 0.0735109219400461 0.00810729414754149 5.17316670785018 -4.73623637254712 0.000597049662453531 48.7360174322852 23.6914091990274 2.05711770975134 0.0416900908556861 -86.8565003673957 52.0774731484976 -1.66783246413908 0.097774715846423 POLR3K essential 1 1 1 2.05711770975134 -1.66783246413908 0.010394697515743 67.9161020599488 41.1175813781828 1.65175333235883 0.101017045813527 -111.43602249981 90.3829621178207 -1.23293173722881 0.219843334331975 SNRNP25 essential 1 1 1 1.65175333235883 -1.23293173722881 7.51442445302754e-05 178.405782001548 75.0074483378362 2.37850754765049 0.018826889252382 -290.085556628918 161.022092434549 -1.80152643803725 0.0739198935929306 WDR90 other 0.560500919951324 1 1 2.37850754765049 -1.80152643803725 5.48831240219149e-06 559.980381504285 166.433796736929 3.36458335075664 0.00100589395097108 -476.80122691054 355.983747651922 -1.33939043581493 0.182762761420393 JMJD8 other 0.0464695411093553 1 1 3.36458335075664 -1.33939043581493 0.0175121683334552 -49.8168537969337 44.1229218854762 -1.12904702744384 0.260941293750844 -267.39780272848 94.3741199089026 -2.83338062369847 0.00533530038715617 CCDC78 other 1 1 1 -1.12904702744384 -2.83338062369847 1.63165472366048e-12 308.707666364956 55.3298964136321 5.57940076477166 1.24428476297735e-07 -240.980611937029 118.966286267766 -2.02562103514466 0.0447455429516588 SPSB3 other 2.05816926842533e-08 1 0.00143876647143071 5.57940076477166 -2.02562103514466 0.0100294481011428 17.0308985629441 5.65928772830561 3.00937138745605 0.00311684027757886 12.6827565684245 12.1681855126587 1.04228823231126 0.299113850512651 MEIOB other 1 1 1 3.00937138745605 1.04228823231126 0.0536670392641347 9.64241681712663 4.93153535117431 1.95525655409335 0.0525882944533884 -1.83607170492647 10.4268658186873 -0.176090470219327 0.860482892721631 HS3ST6 other 1 1 1 1.95525655409335 -0.176090470219327 2.90514106513414e-06 235.38729196132 45.6626576072716 5.15491879569961 8.05471533385983e-07 168.908576603344 97.8866105747872 1.72555342974405 0.0865291719647269 CCNF other 0.0253153992415789 1 0.00884810479424502 5.15491879569961 1.72555342974405 2.00138852441674e-10 210.961473627801 37.2217014254384 5.66770097950502 7.40434247190462e-08 -69.2994230710527 79.7918120250337 -0.868502936733795 0.386534785828819 TBC1D24 other 2.33922290733828e-06 1 0.000865863808664526 5.66770097950502 -0.868502936733795 0.000183218816944049 66.9367955853572 21.1303220783293 3.16780763384604 0.00186839552050301 -36.0432035327996 45.2968731340742 -0.795710631639305 0.427483275109131 AMDHD2 other 1 1 1 3.16780763384604 -0.795710631639305 7.57198334956105e-11 17.3592968318087 2.59493687616371 6.68967981119919 4.37397510985211e-10 4.31825720652429 5.5627418282974 0.776282153623869 0.438829637827013 NTN3 other 9.00611699596792e-07 1 5.58031744514932e-06 6.68967981119919 0.776282153623869 0.0224021031414229 23.8450936263478 29.3601160591932 0.812159379011769 0.417987203183253 -116.619713751967 62.7686462368936 -1.85792940812895 0.0651392686196203 BICDL2 other 1 1 1 0.812159379011769 -1.85792940812895 0.00783296531131322 184.860581638167 108.078904253938 1.71042242622876 0.0892690992406952 -324.194880143041 231.604678974364 -1.3997769025164 0.163658758361357 PAQR4 other 1 1 1 1.71042242622876 -1.3997769025164 9.9070833828221e-07 135.448257687458 28.8182752612713 4.7000820298738 5.86815331781294e-06 -2.61065669471006 61.7553206757125 -0.0422741986624772 0.966336709748632 FLYWCH2 other 0.00904219500350173 1 0.0607999365258599 4.7000820298738 -0.0422741986624772 0.0362785916902643 4.78006097927104 6.26298014086349 0.763224674477733 0.446536144710054 -23.3461941329135 13.4210789326599 -1.73951693824711 0.0840089323192972 ZG16B other 1 1 1 0.763224674477733 -1.73951693824711 6.23028061618499e-05 84.8676379732795 19.9219628298026 4.26000383086351 3.55721085529019e-05 41.3513307637763 41.0942905292812 1.00625488921173 0.31588172961956 ZNF75A other 0.468704010755596 1 0.341776818976281 4.26000383086351 1.00625488921173 0.275642760634683 10.1597715626232 20.0178168532783 0.507536443014232 0.612518971416839 -80.7148021431799 60.5931342441137 -1.33207834765572 0.184841463186424 ADCY9 other 1 1 1 0.507536443014232 -1.33207834765572 0.10213855111625 67.7366288492706 37.0120902401321 1.83012168212602 0.0691652052054467 -75.460922024131 127.228161496565 -0.593114929403175 0.553974274816815 SHANK2 other 1 1 1 1.83012168212602 -0.593114929403175 1.42107904490517e-08 101.228372189842 22.6942095920997 4.46053746789583 1.6007226209952e-05 -247.540320566195 81.4856114886646 -3.03784086593778 0.00281428698789711 CLPB other 0.000150165422675129 1 0.159255893562812 4.46053746789583 -3.03784086593778 5.48130285732537e-08 101.53490664392 17.6702550069867 5.74609175723688 4.69876518023255e-08 -42.5785044071653 73.6446179929711 -0.578161793319766 0.563993937561947 NEU3 other 0.000556078174875659 1 0.000555112118392673 5.74609175723688 -0.578161793319766 0.00636832127261086 69.3109374407221 52.6795629303571 1.31570828581763 0.190279342525084 -417.77935430024 174.006023006888 -2.40094766308005 0.0175774797970896 CYB561A3 other 1 1 1 1.31570828581763 -2.40094766308005 0.475240981262601 -20.3637929684441 23.3344224510115 -0.872693250119908 0.384234480139778 -82.8109153551013 76.2208053219393 -1.08646077675678 0.279029703630593 PPP1R32 other 1 1 1 -0.872693250119908 -1.08646077675678 0.0466028491419525 13.0899509548158 7.16292421973107 1.82745908699664 0.069745066591397 -25.1735364708337 22.4442910432635 -1.12160087490887 0.263938661658099 SLC25A45 other 1 1 1 1.82745908699664 -1.12160087490887 0.000948195210958863 2245.40941233844 1770.58321242811 1.26817502649829 0.206825421838736 -10817.3106965781 4066.74209707748 -2.65994509569511 0.00872057219224165 RPL29 essential 1 1 1 1.26817502649829 -2.65994509569511 0.57067334666082 1.25014996077949 4.37522984377195 0.28573355124624 0.775473797814743 -7.37877978067276 9.88172223250619 -0.746709896013881 0.456399751399488 ITIH3 other 1 1 1 0.28573355124624 -0.746709896013881 1.9629517197417e-06 283.445179716885 61.4793572393037 4.61041221712186 8.83214152495993e-06 -249.81313501787 186.714832508335 -1.33793942164032 0.183039944434013 ZFPL1 other 0.0174270853678668 1 0.0901231721206911 4.61041221712186 -1.33793942164032 0.119872023591898 28.535205857452 57.7302417999183 0.494285230197881 0.621852759213216 -311.7239032956 173.222645838937 -1.79955629811498 0.074010067838977 RPS6KA4 other 1 1 1 0.494285230197881 -1.79955629811498 0.000173721909558008 782.098184987396 195.912372326975 3.99208164189899 0.000101093798040787 -383.639536039962 597.60010321091 -0.641966984240236 0.521849059272 LRP5 other 1 1 0.924603876881038 3.99208164189899 -0.641966984240236 7.07321202752082e-05 83.6958907852938 19.9283290452399 4.19984488389836 4.49044071060749e-05 -42.2421464925364 61.4029346844632 -0.687949960528923 0.492512528056358 TPCN2 other 0.529146991778832 1 0.426816389543242 4.19984488389836 -0.687949960528923 0.187423743832652 54.6807873882985 32.0390792693847 1.70669034926198 0.0898822079518633 -23.129151913674 96.1030727151866 -0.240670264334004 0.810128724866301 FGF19 other 1 1 1 1.70669034926198 -0.240670264334004 0.132043417572054 -332.015425189365 304.611556746178 -1.08996332488469 0.277410081052419 -1961.33555153485 1006.23470447622 -1.94918297173599 0.0530672891112215 PDZK1IP1 other 1 1 1 -1.08996332488469 -1.94918297173599 3.68135536880907e-05 55.535559774659 84.3263374151961 0.658579056994015 0.511136938217209 -1173.38769059451 275.671516316748 -4.2564705497041 3.57229927747971e-05 CMPK1 essential 0.28497371909951 0.515161278805348 1 0.658579056994015 -4.2564705497041 0.0270868691926941 19.8904951455981 8.65296024845471 2.29869253694425 0.0228498103760459 -18.8063736718689 27.1397068155723 -0.692946825095331 0.489373247016294 BEND5 other 1 1 1 2.29869253694425 -0.692946825095331 3.04092957269884e-08 120.051260092978 25.8098550227978 4.6513728956221 7.11552017515513e-06 -192.855150477122 80.1670011859002 -2.40566751436677 0.0173443586379418 COA7 other 0.000314219252746971 1 0.0731404318804195 4.6513728956221 -2.40566751436677 1.01403204949654e-13 227.094575543978 35.6813194016588 6.3645229311061 2.19230419130163e-09 -367.562921646746 110.811966109995 -3.31699666155091 0.00113835714855372 ZYG11B other 1.32270340536329e-09 1 2.73621486116356e-05 6.3645229311061 -3.31699666155091 2.90214589078357e-06 8.22071403847115 33.8287495629114 0.24300969278167 0.808327682761673 -513.848538792464 105.002893092354 -4.89366077123716 2.51382299465997e-06 C1orf123 other 0.0252922014381788 0.036623887209201 1 0.24300969278167 -4.89366077123716 0.000524273924646745 92.327139890224 51.4957716840075 1.79290720132847 0.0749894885394865 -443.468179795282 159.840522594202 -2.77444150330481 0.00622830255106947 MAGOH essential 1 1 1 1.79290720132847 -2.77444150330481 4.07017003856881e-06 144.348832120781 32.2429819389085 4.47690701791422 1.52918368474944e-05 -78.860893824189 99.6855071644733 -0.791096881255514 0.430188510138523 ACOT11 other 0.0349871816515374 1 0.152474905206367 4.47690701791422 -0.791096881255514 2.71266168111915e-06 30.1929872545265 6.19247064860761 4.87575783040901 2.83115665414349e-06 -1.90749047280419 19.1452384390865 -0.0996326307908444 0.920774557496007 FAM151A other 0.0237168010780247 1 0.0300385721004624 4.87575783040901 -0.0996326307908444 1.60840325752968e-14 116.2157700072 16.5367785843591 7.02771518735333 6.37457831698553e-11 -138.176595564465 49.0255542657946 -2.81846065044636 0.00545935401137608 PARS2 essential 2.13692456795393e-10 1 8.35388488440954e-07 7.02771518735333 -2.81846065044636 0.142545066561491 2.73026205975633 4.04514270617308 0.674948267113005 0.50072070969353 -18.0371223501919 11.7198316504388 -1.5390257205202 0.125850210238653 BSND other 1 1 1 0.674948267113005 -1.5390257205202 5.93424208119794e-11 444.786086537214 73.3968001262673 6.06002013401172 1.00491179886289e-08 -432.812937925406 212.649640233472 -2.03533350656137 0.0435319742183332 USP24 other 7.08904559019906e-07 1 0.000122287716803625 6.06002013401172 -2.03533350656137 0.00244088102111318 497.255106511144 164.502154633474 3.02278780250066 0.00293733711263532 -412.381482394174 522.564894509939 -0.789148843955362 0.431246193589857 PLPP3 other 1 1 1 3.02278780250066 -0.789148843955362 7.07636592884476e-22 362.963448063801 36.8285121598712 9.85550126185359 7.00457867815106e-18 12.0605622468942 83.1724134655601 0.14500676058761 0.88490552304439 NOL9 essential 1.00923130877184e-17 1 9.94580126510669e-14 9.85550126185359 0.14500676058761 8.5062291109199e-06 107.382641928795 22.5349878631047 4.76515197528047 4.32965814344792e-06 -0.349966796318929 71.627368986464 -0.00488593677627703 0.99610792548213 PRKAA2 other 0.0707803324319645 1 0.0453791470014776 4.76515197528047 -0.00488593677627703 1.87303038193932e-11 220.667038960285 54.4670532151113 4.05138567142207 8.21584620180169e-05 -388.959270111108 122.808842606641 -3.16719270253977 0.00187209525471704 KLHL21 other 2.28078909608751e-07 1 0.758651238274368 4.05138567142207 -3.16719270253977 0.102963652442851 26.2783558578011 15.1247968869493 1.73743528949311 0.0843095860239462 -33.784313357341 47.9834955531957 -0.704081955010693 0.482445024110878 ZSWIM5 other 1 1 1 1.73743528949311 -0.704081955010693 3.52879255496784e-10 103.250895967057 18.4876710645055 5.58485141837516 1.0598222523835e-07 -19.1216130429962 42.7421161233633 -0.447371697456602 0.655247793124706 GMEB1 other 4.07681403875434e-06 1 0.0012294997949901 5.58485141837516 -0.447371697456602 9.70104352645035e-07 29.057239460618 6.25840903399356 4.6429115295579 7.34178607667062e-06 3.51658779601447 13.2642314534441 0.265118096616249 0.791275339462923 SLC45A1 other 0.00886287336576504 1 0.0753487505048706 4.6429115295579 0.265118096616249 2.72028528247404e-05 687.264086331696 246.754799338267 2.78521061464563 0.00601687331876653 -778.805306448471 525.991054961393 -1.48064363281926 0.140731403020179 SELENON other 0.214739320198501 1 1 2.78521061464563 -1.48064363281926 0.0031035956773629 152.999280193969 107.852416361218 1.41859853822418 0.15801081935541 -953.739543870283 356.807801789908 -2.67297839084767 0.00831772601380017 AK4 other 1 1 1 1.41859853822418 -2.67297839084767 6.87652550943396e-06 324.415289050726 120.203751900388 2.69887822902205 0.0077293281744894 -1360.1252973891 397.419337811039 -3.42239334623369 0.000794007065757664 JAK1 og 0.0576459133455849 1 1 2.69887822902205 -3.42239334623369 0.00466807339417145 68.2130247007123 24.7829279838709 2.75241992169393 0.00661724087356839 -89.2497272313986 81.9892808541867 -1.08855360483188 0.278029614512091 RAVER2 other 1 1 1 2.75241992169393 -1.08855360483188 1.93933608057714e-15 180.711024502527 25.4249622553688 7.10762213479268 4.29071869795104e-11 -45.4489841292676 55.1417183003938 -0.824221397702491 0.411105241720757 LZIC other 2.62100389793234e-11 1 5.64744395024316e-07 7.10762213479268 -0.824221397702491 0.0996589056047765 9.35682990786213 5.57428285357735 1.67857106530884 0.0952903780074557 25.1130307409612 12.0895178427953 2.07725660092616 0.0394602646232765 RBP7 other 1 1 1 1.67857106530884 2.07725660092616 0.00129273122116112 260.659040884281 97.5993171699601 2.67070557912171 0.00838237390410611 -122.283737599121 227.954314455822 -0.536439671655436 0.592428781937947 FBLIM1 other 1 1 1 2.67070557912171 -0.536439671655436 0.535344092982643 5.95488150207215 11.6092119868962 0.512944505518004 0.608725150727977 -13.4769423665129 27.1181133858324 -0.496971974958768 0.619917546682745 SLC25A34 other 1 1 1 0.512944505518004 -0.496971974958768 0.484156069123358 -2.06144456871435 12.3949629166967 -0.166313088838489 0.868128721788944 -28.8553636275769 27.3662371997726 -1.05441473071119 0.293344547962058 AKR7A3 other 1 1 1 -0.166313088838489 -1.05441473071119 0.000594588876023652 19.4887665341056 5.11970464966843 3.80661930085513 0.000202450076829094 14.4284926947351 11.7288926851618 1.23016665614039 0.220498478839244 DRAXIN other 1 1 1 3.80661930085513 1.23016665614039 0.933208224150618 19.9842531483487 57.3247742675343 0.348614598202905 0.72785173827681 11.8345070822235 143.860045791207 0.0822640297181586 0.93454289367594 PDPN other 1 1 1 0.348614598202905 0.0822640297181586 0.0340891097372263 -343.024554483647 188.853059985473 -1.81635687825251 0.0712477982316498 -1263.01696512238 491.915131374548 -2.56755054798407 0.011187682871939 DHRS3 other 1 1 1 -1.81635687825251 -2.56755054798407 0.0113932842514329 6.06563145014502 4.2684089835761 1.42105207666 0.157323345551583 -15.288463112791 10.3046546074427 -1.48364634189181 0.139946526819242 MATN1 other 1 1 1 1.42105207666 -1.48364634189181 0.689244201163131 -275.931494561194 375.681352568781 -0.73448280750287 0.463771426265842 -707.583419698143 906.957743640309 -0.780172422210184 0.436486856595605 LAPTM5 other 1 1 1 -0.73448280750287 -0.780172422210184 8.02718436694173e-05 302.638630800045 261.722402168482 1.15633445319374 0.24933505080253 -1911.18656114388 628.730000521515 -3.03975722417985 0.00278293632619127 SDC3 other 0.59641979846377 1 1 1.15633445319374 -3.03975722417985 1.99021557265643e-10 287.953452785995 72.3960227328757 3.97747613634074 0.000107168290904811 -604.232264186428 188.72344253981 -3.20168102094136 0.00166199353812766 PEF1 other 2.32636298287811e-06 1 0.976624635015544 3.97747613634074 -3.20168102094136 2.00289469443468e-12 102.819258755889 21.0171079180478 4.89216971035278 2.55916507752542e-06 -203.932831433393 59.1529952797027 -3.44754869079925 0.00073552161956467 SYNC other 2.5190406571905e-08 1 0.0272448714153356 4.89216971035278 -3.44754869079925 4.47874039516967e-17 1197.80421130191 173.27354031134 6.91279354683748 1.29748548720146e-10 -1525.88439248983 487.681223891537 -3.12885614154625 0.00211153047776203 RBBP4 essential 6.18290111553172e-13 1 1.6847849051311e-06 6.91279354683748 -3.12885614154625 1.43406871529548e-09 2112.7493524813 449.313877147391 4.70216803873218 5.84552001917904e-06 -2816.43454283186 1244.44537919329 -2.26320462908354 0.0250776048142196 KIAA1522 other 1.60529651990176e-05 1 0.0605712784387332 4.70216803873218 -2.26320462908354 2.64270754549446e-05 16.8829627621804 4.86281016216774 3.47185314646425 0.000676610912089942 -17.8215226503982 13.6864590356787 -1.30212808177338 0.194881906378835 TSSK3 other 0.208879604395882 1 1 3.47185314646425 -1.30212808177338 1.76541187423415e-06 65.0982577889493 49.365573385787 1.31869749147271 0.189215352039604 -365.703805906943 108.967319489563 -3.3560870141618 0.000994338728161183 TMCO4 other 0.0157474739181686 1 1 1.31869749147271 -3.3560870141618 0.139859340345754 65.2965887392267 64.77317740573 1.00808068022074 0.314986842035164 -109.2379625329 142.977363223668 -0.764022780039749 0.446015144044645 UBXN10 other 1 1 1 1.00808068022074 -0.764022780039749 0.0706559613847362 -183.646636855702 79.5058150684558 -2.30985163409216 0.0222159224526677 -211.757429214138 175.497516946433 -1.20661210995238 0.229419903719214 CAMK2N1 other 1 1 1 -2.30985163409216 -1.20661210995238 2.87862480030002e-07 2503.47231161489 445.95835516654 5.61369079110534 9.07197839911495e-08 2333.3829104556 986.89060432795 2.36437848351447 0.0193155559183171 ALPL other 0.00275052599668666 1 0.00105661332414492 5.61369079110534 2.36437848351447 0.222174503514915 24.0260627699054 26.4102874991713 0.909723635937675 0.364447423979847 -35.3891897097056 56.4954253075863 -0.626408059007099 0.532012293069259 WNT4 other 1 1 1 0.909723635937675 -0.626408059007099 0.0991930487763299 6.31037358238827 15.5372885375722 0.406143811201584 0.685342659938026 -55.1495163442295 34.5986344089204 -1.59397956845402 0.113507100115264 TTLL10 other 1 1 1 0.406143811201584 -1.59397956845402 0.000174891182242125 137.92091262804 37.4052855832247 3.68720383971335 0.000338672250186553 4.2273682538842 82.5817286590137 0.0511901158104758 0.959257066895838 SCNN1D other 1 1 1 3.68720383971335 0.0511901158104758 0.0312347633645586 975.466502040202 474.144028576503 2.0573210738703 0.0417518533663103 -370.01459502136 1070.43288825791 -0.345668186282604 0.730177835754295 MXRA8 other 1 1 1 2.0573210738703 -0.345668186282604 6.02322977042014e-05 292.73652664702 117.820159742225 2.48460473392235 0.0141833213162263 -490.375807402227 263.442045413303 -1.86141815985713 0.064843835568987 FAAP20 other 0.453850363201157 1 1 2.48460473392235 -1.86141815985713 0.000132005178296893 354.470246705986 101.232352454501 3.50155101715434 0.000623570405819819 -73.3846405311923 225.809397655402 -0.324984882352777 0.745684669978954 MEGF6 other 0.952549366590379 1 1 3.50155101715434 -0.324984882352777 1.97643055703502e-11 17.1553040468633 2.93108433121329 5.85288654583406 3.20051463201614e-08 -5.58812870746538 6.58631225744504 -0.848445759787455 0.397617728800104 CCDC27 other 2.40393248652169e-07 1 0.000381053272087841 5.85288654583406 -0.848445759787455 0.994278253368678 1.04144982924054 10.3111613733178 0.101002185062829 0.919677595937733 -0.133143600585416 31.1296041139354 -0.00427707336393054 0.996592829384505 DIRAS3 other 1 1 1 0.101002185062829 -0.00427707336393054 0.277102492667302 -15.3484467023333 11.7124628423024 -1.31043717354634 0.191974075495858 -46.2218525678492 36.7454001076565 -1.25789493194872 0.210309375246111 C1orf87 other 1 1 1 -1.31043717354634 -1.25789493194872 7.06451446393103e-07 589.225730783109 123.278820825526 4.77961848464652 4.02722018899161e-06 -546.726858534825 386.634126499646 -1.41406777380094 0.159334615328545 NFIA other 0.00652337265599391 1 0.0422896758748125 4.77961848464652 -1.41406777380094 8.0598579810808e-06 51.408913213448 18.7035769966838 2.74861398023293 0.00669557170087892 -196.314620797498 60.787212133641 -3.22953815295722 0.0015138681578186 OMA1 other 0.0672111557042328 1 1 2.74861398023293 -3.22953815295722 1.09750244685441e-08 96.0134544231415 26.9976972242209 3.55635718208601 0.000497338651381327 -335.751555667676 82.9611971063006 -4.04709150034886 8.11809812617462e-05 MYSM1 other 0.000116708410198498 1 1 3.55635718208601 -4.04709150034886 1.27374952557968e-06 92.214633706243 30.3317775117522 3.04019880373031 0.00277354623045114 -331.640765968965 95.1282647327992 -3.48624845518304 0.000636358014375143 TM2D1 other 0.0115121482121891 1 1 3.04019880373031 -3.48624845518304 1.20917318682731e-06 188.701264317936 73.1573008597116 2.57939073886549 0.0108089042488839 -898.60878349057 231.312005098415 -3.88483417930791 0.000150271322280985 USP1 other 0.010951481553095 1 1 2.57939073886549 -3.88483417930791 1.04054084488153e-05 337.003310250361 97.6522096794492 3.45105667712589 0.000718582870510488 -670.216726276539 290.814791355913 -2.30461704905614 0.02250673736593 FUBP1 other 0.0858758359280727 1 1 3.45105667712589 -2.30461704905614 0.810263138930081 2.46157065672328 15.4923061571862 0.158889879385805 0.873961148100446 -25.2311087436266 46.1371206807642 -0.546872201197986 0.585247945282681 NEXN other 1 1 1 0.158889879385805 -0.546872201197986 0.00377163245514911 41.791834715775 21.1024164130357 1.98042887116751 0.0494139180954997 -125.532075184537 62.8444030750291 -1.99750604735104 0.047508825527542 DNAJB4 other 1 1 1 1.98042887116751 -1.99750604735104 0.0235091109305768 -21.147634232526 10.201402218104 -2.07301249185099 0.0398371587398011 -75.0554741589818 31.2331367583821 -2.40307192772877 0.0174474541267113 ADGRL4 other 1 1 1 -2.07301249185099 -2.40307192772877 0.0557368425142002 8.44900691458362 4.1703297271857 2.02598055005241 0.0444709548700616 -7.54808707020113 12.2202320731574 -0.617671335946316 0.537692623104288 LRRIQ3 other 1 1 1 2.02598055005241 -0.617671335946316 9.7445266078136e-05 57.2733296521259 21.9938613848906 2.60405977149023 0.0100968279320105 -167.104864562243 65.018367844387 -2.57011780059117 0.0110963332944043 TYW3 other 0.715735479343909 1 1 2.60405977149023 -2.57011780059117 0.00516515998123189 -18.9390189421012 24.8057664517394 -0.763492592698066 0.446337751967002 -258.64724803431 78.3886039978426 -3.299551654746 0.00120312850656225 SNX7 other 1 1 1 -0.763492592698066 -3.299551654746 0.042036732382845 33.848952618705 13.8086335542142 2.45128907837335 0.0153754672519688 4.9863100570749 43.8402930990366 0.11373806388134 0.909596520893882 NTNG1 other 1 1 1 2.45128907837335 0.11373806388134 0.0772508841497694 15.0554207260861 20.4848414724657 0.734954221946145 0.463499785516837 -119.029895597139 65.0344193943771 -1.8302599870282 0.0691698757195981 FAM102B other 1 1 1 0.734954221946145 -1.8302599870282 1.50659231072713e-07 161.645405405405 29.7891026797447 5.4263267726865 2.22404640449518e-07 -52.8317472401979 93.6640661464874 -0.564055666316802 0.573547565173199 HENMT1 other 0.00147751507913009 1 0.00253207683151777 5.4263267726865 -0.564055666316802 3.88714677655947e-05 50.977662436912 15.2023909301865 3.35326611919238 0.00100525505175998 -113.571048735054 49.007269343936 -2.31743270448319 0.0217970868264728 C1orf52 other 0.29966014500497 1 1 3.35326611919238 -2.31743270448319 0.277720222612236 -15.0954574989663 12.6771514386503 -1.19076099800646 0.235579607641993 -54.115265717605 39.7315953480884 -1.36202096199514 0.175180221852683 WDR63 other 1 1 1 -1.19076099800646 -1.36202096199514 0.35381289317144 -3.5723738374754 106.629211857705 -0.033502768849522 0.97331676199898 -493.56909081669 350.033929330596 -1.41006070971631 0.160525264425827 GBP2 other 1 1 1 -0.033502768849522 -1.41006070971631 3.47974552964934e-08 66.4281849724582 14.485684760416 4.58578148504112 9.47104149173295e-06 -120.632093780017 46.7272682154566 -2.58162093328011 0.0107915381682361 ATXN7L2 other 0.000357961422635028 1 0.0963489050953993 4.58578148504112 -2.58162093328011 0.390772274913621 -46.7167556029887 166.319454118774 -0.280885695846661 0.779172657759385 -750.076840981858 545.980327858039 -1.37381660603875 0.171482181875432 GBP4 other 1 1 1 -0.280885695846661 -1.37381660603875 2.6124369014023e-07 119.921003703424 27.5270715905494 4.35647516332959 2.3858258731963e-05 -236.727080341622 90.4365932256807 -2.61760280764755 0.00972681220229326 ZNF326 other 0.00250741693796593 1 0.23323833736367 4.35647516332959 -2.61760280764755 0.00819939765570097 25.858123569794 8.23249926181867 3.14098097642363 0.00201715811665712 18.0411899313501 28.1305151539382 0.641338767975758 0.5222498087921 HFM1 other 1 1 1 3.14098097642363 0.641338767975758 0.874346096909033 0.10888065905837 3.58982804829984 0.0303303271336175 0.975842378818482 -5.82871035195114 11.7939105104697 -0.49421354747239 0.62185057070509 GFI1 other 1 1 1 0.0303303271336175 -0.49421354747239 5.81265396632602e-05 44.4419129720853 9.76895080268798 4.54930256787217 1.10820647051095e-05 22.0976190476192 38.2835029976843 0.577209955132784 0.564668753034732 KCNT2 other 0.439262260235257 1 0.112072920362772 4.54930256787217 0.577209955132784 2.81713956355578e-10 132.158553054662 21.5966009549776 6.11941450092875 7.54066173424477e-09 -119.611105614643 68.1289307760792 -1.75565804794106 0.0811480072596835 AGL other 3.26926633877165e-06 1 9.22599963184848e-05 6.11941450092875 -1.75565804794106 0.416490435604126 -100.473738709171 94.3375061107474 -1.06504552485435 0.28853321952176 -314.501534720746 290.06636069255 -1.08423994416262 0.279963998812997 VCAM1 other 1 1 1 -1.06504552485435 -1.08423994416262 1.24411803999206e-06 121.129683902998 27.0182602093821 4.48325254713981 1.43378021477361e-05 -129.508722945924 83.0750009649338 -1.55893736312553 0.121077297771583 EXTL2 other 0.0112518035536882 1 0.143220305653736 4.48325254713981 -1.55893736312553 2.06143524699815e-06 95.9339515361074 36.640051941326 2.61828099178823 0.00972574624580502 -407.002829063543 112.659820683935 -3.61267066282114 0.000410473521889836 SLC30A7 other 0.0182684391588976 1 1 2.61828099178823 -3.61267066282114 3.57020284274192e-07 96.0193376305846 19.3333258824883 4.96651937769056 1.78182433503196e-06 -117.605492578598 70.3440645095297 -1.67186092243313 0.0965692978390986 ZNF281 other 0.00338455229491934 1 0.0191670843719388 4.96651937769056 -1.67186092243313 0.1439563912046 -6.52411140922045 3.94621272172888 -1.65325892679251 0.100289202139334 -20.6867919356084 12.4844322675416 -1.65700702220895 0.0995278764559508 NLRP3 other 1 1 1 -1.65325892679251 -1.65700702220895 3.59570260364922e-13 430.84778200113 63.6551344746982 6.76846864839134 2.48646588521715e-10 -356.755147046019 200.782295433928 -1.77682572198413 0.0775457928414023 ZNF496 other 4.62515225907399e-09 1 3.19908700792038e-06 6.76846864839134 -1.77682572198413 3.12454434899072e-05 56.6781821111574 13.3424749877255 4.24795116073285 3.68436300930328e-05 -8.9114433806447 44.10048685848 -0.202071315204339 0.840122574041701 TRIM58 other 0.244401858978054 1 0.353072507181533 4.24795116073285 -0.202071315204339 1.51674351646426e-06 16.6212341699439 5.84681781508826 2.84278297966653 0.00509145014777438 -66.5786233054389 19.8753904684547 -3.34980202834805 0.0010214698288277 C1orf74 other 0.0136142898037832 1 1 2.84278297966653 -3.34980202834805 1.8590835609551e-08 81.9197539876629 18.4538047830968 4.43917961366424 1.70025250328516e-05 -133.230371938533 53.8738771766365 -2.47300508002627 0.0144707783044076 FLVCR1 other 0.000195092228886628 1 0.168852076101249 4.43917961366424 -2.47300508002627 0.296192004422329 -199.868484768445 140.28245246211 -1.42475756062526 0.156224788581406 -473.497006515232 419.351143215655 -1.12911819646986 0.260581275956005 ATF3 other 1 1 1 -1.42475756062526 -1.12911819646986 2.52736156367866e-09 67.2947440104007 11.8446617753894 5.68144074406788 6.60952975257785e-08 -76.9559310249585 40.9952299406821 -1.87719232545615 0.0624080328045175 RBM15 other 2.79273452786492e-05 1 0.000775496125869959 5.68144074406788 -1.87719232545615 9.44463888748052e-05 52.5202805119953 50.7966378413391 1.03393221960949 0.302778325224435 -623.993272577566 164.414777806608 -3.79523836544386 0.000211132919968545 DENND2D other 0.694976594955274 1 1 1.03393221960949 -3.79523836544386 0.0209885052306344 207.654822335025 86.8129225928272 2.39198055004985 0.0180575696770006 -43.6319423708569 189.731883823515 -0.229966316106588 0.818446574179362 SNED1 other 1 1 1 2.39198055004985 -0.229966316106588 9.61387074943126e-07 141.009274172865 32.7635018883575 4.30385233707183 2.962877596019e-05 -152.525413353852 99.2720735761004 -1.53643827371983 0.126469732634496 BPNT1 other 0.00878672371900774 1 0.287191725382122 4.30385233707183 -1.53643827371983 0.0031672716223741 29.807913000895 14.9265673202525 1.9969703925464 0.0475565117345882 -81.0507978858136 45.5464570293197 -1.77951926828553 0.0770892882313965 SPATA17 other 1 1 1 1.9969703925464 -1.77951926828553 0.551364734130195 -12.8910748340565 27.721182479804 -0.465026152598224 0.642565359082579 -92.5396907089302 84.8200475505332 -1.09101201168035 0.276960662767033 C1orf115 other 1 1 1 -0.465026152598224 -1.09101201168035 4.4334110642762e-11 242.732715560118 38.5716522259629 6.29303391356237 3.0049119065639e-09 -188.711660912722 120.314063981062 -1.56849211695174 0.118792496841288 BROX other 5.32142330045073e-07 1 3.72939616723646e-05 6.29303391356237 -1.56849211695174 0.573482200253939 -80.7984003690923 82.53526561638 -0.9789560833867 0.329147070180386 -198.558810364892 262.073093774347 -0.757646683622765 0.449827845714122 KIF26B other 1 1 1 -0.9789560833867 -0.757646683622765 1.03774029144036e-13 124.174495318272 17.9116127622741 6.93262504981188 1.08495161243789e-10 -106.393911176016 56.6916265347424 -1.87671297648894 0.0624616541900401 TFB2M essential 1.35321334003823e-09 1 1.41249850423289e-06 6.93262504981188 -1.87671297648894 7.3374875185483e-14 135.142668155657 19.0293693434618 7.10179437460389 4.34367403945744e-11 -101.476309595396 60.2294117413826 -1.68482983083285 0.0940601175761761 CNST other 9.60770615678714e-10 1 5.7154063011181e-07 7.10179437460389 -1.68482983083285 1.36225694871072e-10 252.644352733659 35.550351552631 7.10666257011914 4.14950176749281e-11 -55.1874894671994 158.720807533056 -0.347701667632367 0.728539019844626 PPP1R21 other 1.6032654433333e-06 1 5.46489382778803e-07 7.10666257011914 -0.347701667632367 0.574570114902029 21.3436184735731 57.6633266115932 0.370141990200094 0.711781980222505 -187.241444139501 213.053377706775 -0.878847574044101 0.380844309063637 KLHDC8A other 1 1 1 0.370141990200094 -0.878847574044101 0.000247813301111896 469.366629911467 120.815772801329 3.88497808711865 0.000151972034498852 -339.926391301839 543.075198993986 -0.625928769959542 0.532294296769326 PKDCC other 1 1 1 3.88497808711865 -0.625928769959542 0.00537228985778631 7.0461661854347 2.18909412252553 3.21875889799824 0.00157206790325058 1.51947385306383 9.8876450037774 0.153673989355741 0.878069298871678 OXER1 other 1 1 1 3.21875889799824 0.153673989355741 0.0440844435111354 12.0154315046519 5.32467689081036 2.25655598471878 0.0254523145447122 -12.7059993583574 24.0503660004396 -0.528307941680603 0.598051080040804 HAAO other 1 1 1 2.25655598471878 -0.528307941680603 3.94187920533524e-08 53.1055154025146 10.5852180219678 5.01695055239329 1.39870896859579e-06 -53.9040945814997 33.9940933948933 -1.58569001841941 0.11480902456066 B3GALNT2 other 0.000404003199754808 1 0.0151480181298924 5.01695055239329 -1.58569001841941 4.11883844987687e-07 378.235727783457 77.4596659734495 4.88300230875128 2.56385820896335e-06 -381.984280104943 273.605826945174 -1.39611164122425 0.164664441100846 MAPKAPK2 other 0.0038869478451488 1 0.0272922706344149 4.88300230875128 -1.39611164122425 0.628186937620714 -1.34238238863436 1.49611923210483 -0.897242920101906 0.370980813055327 -3.16730243939078 5.28633462690366 -0.599149063184817 0.549948198145866 IL24 other 1 1 1 -0.897242920101906 -0.599149063184817 0.0760904766332396 -15.8214532776225 6.93210783680209 -2.28234379067612 0.0238292169460061 -12.0011068374887 24.4936639465306 -0.489967808151815 0.624849465145167 FCMR other 1 1 1 -2.28234379067612 -0.489967808151815 0.393563961214645 -247.922301984797 216.012596529144 -1.14772150313627 0.252851906868077 -797.604843204615 763.251246541941 -1.04500955199002 0.29764554122761 PIGR other 1 1 1 -1.14772150313627 -1.04500955199002 0.317023463108218 337.7268839244 280.348800982486 1.20466676775799 0.230144794358471 -402.888114319238 892.164027746066 -0.45158524866451 0.65219099635851 CAPN2 other 1 1 1 1.20466676775799 -0.45158524866451 0.00981365641928587 100.893033100333 36.6183497449581 2.75525887439055 0.00662258646841069 -24.324822581506 113.380703468777 -0.214541115351296 0.830428625157388 MRPL55 essential 1 1 1 2.75525887439055 -0.214541115351296 6.92662194066065e-11 466.199639747244 73.4884951384029 6.34384523549214 2.28365935172539e-09 -358.36928604454 243.01156655189 -1.4747005302236 0.142295539031531 WDR26 essential 8.25791867765562e-07 1 2.84863667534225e-05 6.34384523549214 -1.4747005302236 0.165873608202142 43.8710743095003 40.217561039433 1.0908437303417 0.277045455624364 -129.793531173301 127.174968242672 -1.02059023852581 0.30904922479732 TRIM17 other 1 1 1 1.0908437303417 -1.02059023852581 0.103401418110821 11.8080570259475 6.31629759452136 1.86945862655198 0.0635347674231355 -9.05403825544766 21.8145634736046 -0.41504558486366 0.678709578042114 RFTN2 other 1 1 1 1.86945862655198 -0.41504558486366 2.8967773521215e-06 40.1717586368504 8.84927490474669 4.53955370007802 1.11591796835713e-05 -27.7658035802861 28.879388341727 -0.961440154193576 0.337809305005844 DISC1 other 0.0252512081784431 1 0.112808147421223 4.53955370007802 -0.961440154193576 0.0847424374339974 148.805415162455 66.433293303085 2.23992230045812 0.0265466263801602 127.170596551463 432.557293656567 0.293997115333423 0.769161186290897 CAPN13 other 1 1 1 2.23992230045812 0.293997115333423 7.78607078306376e-13 80.4916197662193 9.98980836718709 8.05737375609778 2.06272693106415e-13 -33.7266088478904 62.0043976264011 -0.543938980765614 0.587275221933016 MEMO1 other 9.91633974931001e-09 1 2.82572962286479e-09 8.05737375609778 -0.543938980765614 6.64504542813599e-07 267.199687673944 49.7505551863313 5.37078805800655 2.86149977705184e-07 -274.968068050449 308.790028048966 -0.890469390439142 0.374611989489712 DPY30 other 0.00615464960549138 1 0.00323435319800169 5.37078805800655 -0.890469390439142 5.44421352162663e-06 20.6264618249534 8.97975744333957 2.29699543168088 0.0229663525126898 -96.2393420235878 27.0669784326385 -3.55559976016895 0.000501251651308375 TYW5 other 0.0461288211687425 1 1 2.29699543168088 -3.55559976016895 3.39572815070555e-05 53.9753210397689 14.9332163134673 3.61444714298366 0.000407127849254927 -67.817104347182 44.2879416540921 -1.53127695292011 0.127752597032523 MAIP1 other 0.264459308376948 1 1 3.61444714298366 -1.53127695292011 0.391681428884193 4.19938498790364 9.40836494846942 0.446345885911537 0.655974391990621 -30.9954830451296 29.2242729082596 -1.06060750056743 0.290528862401517 KCNF1 other 1 1 1 0.446345885911537 -1.06060750056743 0.482284177106072 16.9355807729458 53.903254108991 0.314184756614183 0.753808712382113 -164.535128476787 167.290847381226 -0.983527377931448 0.326900678519276 PQLC3 other 1 1 1 0.314184756614183 -0.983527377931448 0.00047061248351812 149.90392837118 44.4282076785494 3.37407102838307 0.000931811936503383 -144.45880641996 127.402316588548 -1.13387896145167 0.258562794093477 ARL5A other 1 1 1 3.37407102838307 -1.13387896145167 2.96881728963997e-07 563.603067117233 100.476680431147 5.60929227258306 9.10590815490401e-08 196.457960471958 314.683413204679 0.624303513398644 0.533346093316576 FAM84A other 0.00283195481258757 1 0.00106047406372012 5.60929227258306 0.624303513398644 3.80846952213577e-08 28.953712473747 5.03237026479274 5.75349406944712 4.53228657137724e-08 -23.9973026397068 21.4596574637228 -1.1182518956919 0.265189561014559 CLHC1 other 0.000390825142361573 1 0.000535761595602503 5.75349406944712 -1.1182518956919 1.93795922713356e-06 25.3112053700119 4.7860976504758 5.28848494503568 4.13398159106823e-07 3.88551249845569 20.4094712357914 0.190377910998586 0.849262117402326 PRORSD1P other 0.0172129538554003 1 0.0046292325856782 5.28848494503568 0.190377910998586 0.0129132353053739 230.811599129726 82.1727201973295 2.80885917583664 0.00560801112499463 -32.0764209953766 275.944354607273 -0.116242352705596 0.907609978318478 FRZB other 1 1 1 2.80885917583664 -0.116242352705596 1.84175492165343e-05 47.2065925527464 10.4051532035518 4.53684742831391 1.1286417273167e-05 -7.42122407507025 34.9825627063917 -0.212140663831764 0.832272459227633 DUSP19 other 0.147911337757987 1 0.114026673710806 4.53684742831391 -0.212140663831764 7.2886302462118e-06 234.766069786861 49.3278588986716 4.75929981613662 4.41886769374704e-06 -135.67770177377 208.82424361461 -0.649721983545964 0.516833535238172 CFAP36 other 0.0609548147490693 1 0.0462699636212252 4.75929981613662 -0.649721983545964 8.65328832098078e-05 65.3297770605463 17.2994608488768 3.77640538229767 0.000225323793198333 -64.1931444623751 58.1615149814442 -1.10370482066802 0.271409989763922 NUP35 other 0.639824138453319 1 1 3.77640538229767 -1.10370482066802 2.86022536513537e-08 63.3058122463078 12.1596936504955 5.20620124699674 6.12050435974964e-07 -48.2867691510493 33.4014512789404 -1.44564883566883 0.150320942235231 CCDC138 other 0.000296176336559767 1 0.0067815188306026 5.20620124699674 -1.44564883566883 3.46400288377206e-16 110.17961430192 11.8721336266029 9.28052343135962 1.54679912326231e-16 7.01905615543698 40.2638872268219 0.174326341515313 0.861839454967893 WDCP other 4.73286714009776e-12 1 2.18052272406288e-12 9.28052343135962 0.174326341515313 1.3518850969888e-08 147.905649464532 24.9473062198327 5.92872225005798 1.9547563288374e-08 -26.1582521735887 79.3587795928312 -0.329620141688162 0.742137833280285 SMC6 essential 0.000143042962112384 1 0.000235000805852832 5.92872225005798 -0.329620141688162 0.442320593851647 16.8139109668271 13.1784724998121 1.27586190031256 0.203937893928342 13.0538546214411 41.9214597867629 0.311388360229837 0.755929280973363 VSNL1 other 1 1 1 1.27586190031256 0.311388360229837 0.0092958749372147 34.8877048620931 51.5078636815671 0.677327739270582 0.499220919116792 -314.237647339839 125.635881312473 -2.50117756215111 0.0134309762085562 CCDC74A other 1 1 1 0.677327739270582 -2.50117756215111 8.09187410117635e-05 557.770026675782 169.301151215138 3.29454361457353 0.00122008270884307 -926.263064723875 551.538262693833 -1.67941759869896 0.0950723972179757 H3F3A essential 0.600821652012344 1 1 3.29454361457353 -1.67941759869896 1.76875010146883e-12 409.176511882017 56.5490383565946 7.23578196505794 1.9657196476845e-11 -137.880905145313 184.221773734839 -0.748450643753829 0.455315308380326 COQ8A other 2.22827137783044e-08 1 2.60634768086488e-07 7.23578196505794 -0.748450643753829 0.851171619679506 -2.1235832986251 10.0642568254802 -0.211002494813995 0.833157220552643 -12.6967493273216 22.4657623064229 -0.565159960038021 0.572766572052364 SLC16A14 other 1 1 1 -0.211002494813995 -0.565159960038021 0.26465270921073 -13.9836879432624 12.8465972205041 -1.08851298933412 0.278413954090649 -59.3390070921986 40.2357471896205 -1.47478327698376 0.142726236733198 TEKT4 other 1 1 1 -1.08851298933412 -1.47478327698376 0.000371224909476559 14.7130684632917 67.0875531646179 0.21931144853635 0.826743662032662 -340.665510750024 109.046591433411 -3.12403630660983 0.00219007250742229 SGCB other 1 1 1 0.21931144853635 -3.12403630660983 0.117392751070488 -142.089527395224 82.064413527441 -1.73143901586175 0.0856923092733136 -263.409169721588 133.390534473524 -1.97472160045862 0.0503710169060123 SPATA18 other 1 1 1 -1.73143901586175 -1.97472160045862 0.171431369191779 -4.50610396542521 5.02390757289964 -0.896932099175628 0.371128439434421 -28.4448462099167 15.3556881579238 -1.85239801156281 0.0658463013948431 NOSTRIN other 1 1 1 -0.896932099175628 -1.85239801156281 0.104563831807591 -19.5683317009468 14.5648576253602 -1.34353058603708 0.181063843896344 -80.3415724334431 38.8501660922781 -2.06798530133985 0.0403032144053068 CFAP221 other 1 1 1 -1.34353058603708 -2.06798530133985 0.0383293267573838 154.732981778081 102.056961096011 1.51614333913504 0.131546461226863 -295.232121996224 238.194598615185 -1.23945766911863 0.217073885571485 SGPP2 other 1 1 1 1.51614333913504 -1.23945766911863 0.0485013394445596 338.299840843644 203.138568673444 1.6653648937907 0.097859900499737 -521.583396785957 535.546725417608 -0.973926964783955 0.331610280559152 INHBB other 1 1 1 1.6653648937907 -0.973926964783955 3.77736139169295e-07 66.6182468917922 16.3546238555998 4.07335854862734 7.41539831110012e-05 -131.105023838373 49.8420941395852 -2.63040761231275 0.00940022905162167 BBS5 other 0.0035737616126807 1 0.687704039371425 4.07335854862734 -2.63040761231275 6.53727849327974e-19 387.684211905948 49.3394538784182 7.85748891467822 6.13024371957028e-13 -2.14822144748228 74.4138965808805 -0.0288685520606676 0.977006563468625 SMARCAD1 other 9.17637782101677e-15 1 8.35307009228646e-09 7.85748891467822 -0.0288685520606676 0.097912594613025 -13.6027812000315 6.31462647444038 -2.15417036226787 0.0327719578391307 -11.650384020551 9.52373657344911 -1.22329969237397 0.223073041940866 HPGDS other 1 1 1 -2.15417036226787 -1.22329969237397 0.0015308347073093 -15.9143503776938 145.797266714515 -0.109153969318613 0.913220649937764 -618.35563567722 221.800329222749 -2.78789322740914 0.00596529736087661 PDLIM5 other 1 1 1 -0.109153969318613 -2.78789322740914 4.3954088751635e-05 11.6479179499358 2.70336759263972 4.30866966876751 3.00195670876798e-05 -10.634197421835 13.7837327800867 -0.77150345204009 0.441655458475548 NEURL3 other 0.336908090281283 1 0.290889605079617 4.30866966876751 -0.77150345204009 3.73938556188832e-31 95.4530401304913 6.45158223397585 14.7952915531028 5.61137370425807e-31 -12.2782058534388 32.1502049888259 -0.381901324041518 0.70308234344501 ANKRD23 other 5.42510057318757e-27 1 8.14827575595315e-27 14.7952915531028 -0.381901324041518 0.488207950166336 -80.0071688009615 206.899327625047 -0.386696127625675 0.699518469819283 -453.878803001176 394.83052579079 -1.14955347510712 0.252121599017673 MSX1 other 1 1 1 -0.386696127625675 -1.14955347510712 1.67361036194816e-13 84.4532843514901 17.0917347056121 4.9411768791239 2.05149719468208e-06 -76.2104031093397 31.572301372972 -2.41383743962931 0.0169907184203139 PACRGL other 2.17134208359154e-09 1 0.0219879469326025 4.9411768791239 -2.41383743962931 0.289435408654123 -11.2218617746054 12.4818068368026 -0.899057477922001 0.370063018988827 -36.9810501809256 23.3942713219089 -1.58077375747509 0.116036137640191 C1QTNF7 other 1 1 1 -0.899057477922001 -1.58077375747509 1.1566752408595e-08 198.121482606907 41.5643227069969 4.76662362583272 4.28116187433149e-06 -195.741630529969 99.7638730062701 -1.96204923316948 0.0515477221358881 ERCC3 other 0.000122815777074462 1 0.0449008257379887 4.76662362583272 -1.96204923316948 0.000131857434283197 -37.5304142554061 34.2823624928692 -1.09474410531691 0.275338007827658 -414.964690179986 95.7978469655969 -4.33167031748646 2.65714140793812e-05 RNF149 other 0.951615103221831 0.384089790517455 1 -1.09474410531691 -4.33167031748646 1.34634240073473e-16 261.797986582547 35.0642795124605 7.4662303125183 5.71140825351219e-12 -211.984159730052 84.1717512050492 -2.51847153819624 0.0128076834478552 IWS1 other 1.84812421348857e-12 1 7.65442934135703e-08 7.4662303125183 -2.51847153819624 0.583143512739801 67.0450443998858 67.1315480379076 0.998711430906181 0.319521746152412 -37.1431538241186 265.039701236414 -0.140141849129942 0.888733449056176 CDC42EP3 other 1 1 1 0.998711430906181 -0.140141849129942 4.83054153169837e-16 225.837309684507 24.1870698508777 9.33710908666815 1.10092841302675e-16 -14.5419810922087 94.582127504857 -0.153749777847426 0.878009640698317 DHX57 other 6.58934170338975e-12 1 1.55340999078074e-12 9.33710908666815 -0.153749777847426 0.00260272069517125 225.053431277162 93.2965575794965 2.41223724771836 0.0170231754496562 -380.459979243692 267.578562377301 -1.42186270777261 0.157075179713672 FZD5 other 1 1 1 2.41223724771836 -1.42186270777261 0.391075226722545 17.4755335019784 14.3503287247834 1.21777931621856 0.225158436631286 -4.70275669715249 41.157363459497 -0.114262826912625 0.909177324498011 CRYGC other 1 1 1 1.21777931621856 -0.114262826912625 2.84423341140275e-20 445.193784104734 48.7240800841294 9.13703826395572 4.15774876176583e-16 52.9414958849679 89.3274801542374 0.592667517247284 0.554296106803782 DCAF16 other 4.02402143045262e-16 1 5.84537898416658e-12 9.13703826395572 0.592667517247284 7.05248809133463e-09 54.700052012834 20.7855954551406 2.63163266748299 0.00937966330486266 -109.079213039555 33.9882797685879 -3.20931844101055 0.00162527505709245 GNPDA2 other 7.58777193746693e-05 1 1 2.63163266748299 -3.20931844101055 0.937758210472492 59.4010901708083 228.659390352079 0.259779797712857 0.795382876490497 171.386620764739 505.788717790497 0.338850224879331 0.735187160691173 ALPP other 1 1 1 0.259779797712857 0.338850224879331 0.601362270527976 585.036986361832 971.72441312935 0.602060603250436 0.548024965680044 2143.09668829354 2149.42952574853 0.997053712448291 0.32031270627857 ALPPL2 other 1 1 1 0.602060603250436 0.997053712448291 1.95931849969142e-08 208.774346344724 58.1455555381021 3.59054693712431 0.000443145120941819 -181.227753602838 95.2965696530804 -1.901723789876 0.0590746082470321 PAQR3 other 0.000205258206027673 1 1 3.59054693712431 -1.901723789876 0.0794227631438138 15.5163874056343 15.6616638077327 0.990724076069963 0.323384555396829 -35.3148591419628 29.4782366268767 -1.19799768178008 0.232770446970325 NIPAL1 other 1 1 1 0.990724076069963 -1.19799768178008 0.691387334741605 -26.3410727529996 35.157177175215 -0.749237420903332 0.454864506443149 -6.80088002146126 56.2459066081401 -0.120913332748681 0.903918328025279 ANTXR2 other 1 1 1 -0.749237420903332 -0.120913332748681 1.41692057432878e-11 59.1462034015523 12.1457314347904 4.86971111777864 2.77652527128999e-06 -32.8602358944258 18.6005099907354 -1.76663091016284 0.0792972301361886 HELQ other 1.73232709417437e-07 1 0.0294811453305571 4.86971111777864 -1.76663091016284 4.00774393734102e-10 118.553564423471 38.5909551530998 3.07205571754157 0.00251972565612573 -188.753083800928 59.0998945375284 -3.19379730332801 0.00170718920668843 MRPS18C other 4.6185241133918e-06 1 1 3.07205571754157 -3.19379730332801 1.04864145001477e-07 463.1064098053 82.2791527194459 5.62847810774611 1.01006723884034e-07 107.278966950764 198.828150063288 0.53955622942031 0.590391929925367 CGGBP1 other 0.00104182528058968 1 0.00117369813153247 5.62847810774611 0.53955622942031 0.099534602604402 10.3594916671645 16.5722443382993 0.625110966003751 0.532823399065943 -100.519906218267 56.3491365516905 -1.78387660165932 0.076412966016864 GPR155 other 1 1 1 0.625110966003751 -1.78387660165932 0.493531304097063 -114.117737909339 297.65555233028 -0.383388574531657 0.701960410066508 -1143.49416981068 961.886117004023 -1.18880411058672 0.236346665871981 DAPL1 other 1 1 1 -0.383388574531657 -1.18880411058672 0.0627107445504167 636.03946916927 324.806731645362 1.95820901231728 0.0520484458376122 2139.35671409086 1204.95504066091 1.77546600653037 0.0778353570341661 CLDN1 other 1 1 1 1.95820901231728 1.77546600653037 2.35007425231355e-07 356.769029557938 89.2074137430091 3.99932039937541 9.85982407918063e-05 -750.446689068191 283.347762854246 -2.64850049108812 0.0089327851227548 HIPK1 other 0.00226547157923027 1 0.902765492689778 3.99932039937541 -2.64850049108812 0.770965113014425 433.978038689287 1147.88271888385 0.378068274354081 0.705893819984881 1815.64030176625 2517.59957796632 0.721179141296526 0.471878724383594 COL6A3 other 1 1 1 0.378068274354081 0.721179141296526 0.886839295837283 -1.18666815866037 2.44127858246433 -0.486084696430874 0.627602578838017 -1.69970116243862 5.80723505677517 -0.292686820116851 0.770158100579094 KBTBD8 other 1 1 1 -0.486084696430874 -0.292686820116851 0.693158499705287 -7.41894473066285 11.20327150476 -0.66221234819764 0.508831372040619 -21.2195177513757 26.3946480488066 -0.803932589369577 0.422683216145228 EOGT other 1 1 1 -0.66221234819764 -0.803932589369577 0.00485274562977315 13.5940585978944 4.55333745660582 2.98551529014671 0.00330047741259157 -6.92094841690856 15.3363531567885 -0.451277324286515 0.652432865032654 SLC22A15 other 1 1 1 2.98551529014671 -0.451277324286515 0.911940498747642 2.39156343177624 9.8954741612659 0.241682550305431 0.809347668787766 -11.8707360144825 39.9529796229546 -0.297117664977915 0.766777063914058 IGFN1 other 1 1 1 0.241682550305431 -0.297117664977915 0.000715086996949647 748.708857574232 626.717296502607 1.19465165833526 0.234096264577481 -6930.34507632948 2167.25854124906 -3.19774726661606 0.00168754865203046 ATP1A1 other 1 1 1 1.19465165833526 -3.19774726661606 0.0349165450728747 -56.5536381166247 76.5559170144665 -0.738723279951541 0.461199420957138 -463.632555879279 182.490855709417 -2.54057965850918 0.012056641301044 EIF4E3 other 1 1 1 -0.738723279951541 -2.54057965850918 0.678504934715844 -14.7635529302644 39.9247695860225 -0.369784298903832 0.712051234095558 47.8843626777675 95.17102857481 0.503140119370756 0.615584615313857 PROK2 other 1 1 1 -0.369784298903832 0.503140119370756 0.426094265113175 -1.24074032529449 18.2571239202954 -0.0679592432362925 0.945909189660584 79.755106561974 63.6874275988751 1.25228965227326 0.212426409373397 LMOD1 other 1 1 1 -0.0679592432362925 1.25228965227326 0.271293384057929 -634.403567460365 439.785192237743 -1.44253053230909 0.151265741210131 -1773.07497162519 1666.2900633929 -1.06408542580807 0.289023027323591 ELF3 other 1 1 1 -1.44253053230909 -1.06408542580807 0.494798658403126 -3.96104382929642 11.6900423264601 -0.338839134938862 0.735204781945226 -22.9524221453287 20.5017086627523 -1.11953703580955 0.264700569574858 PDCL2 other 1 1 1 -0.338839134938862 -1.11953703580955 0.0167741304438267 17.7608238219727 8.79263026711408 2.01996709544369 0.0451320248465826 -24.144979170652 23.4693804553367 -1.0287863889974 0.30520370897826 TMEM169 other 1 1 1 2.01996709544369 -1.0287863889974 0.141218018077319 902.72772356975 1172.61661059503 0.769840470801171 0.44258928947068 -2049.88457909514 2023.6147984245 -1.01298161126865 0.312678708905752 IGFBP7 other 1 1 1 0.769840470801171 -1.01298161126865 0.0119447978363636 285.931362429962 230.851588291165 1.23859387126818 0.217554007040167 -1203.14072544972 591.329150202067 -2.03463794240245 0.043761608648358 ARPC2 other 1 1 1 1.23859387126818 -2.03463794240245 0.000133742179000449 86.6079471344051 26.9709662098239 3.21115478254016 0.00162189237208766 -106.690128056382 71.1322729124505 -1.49988357869144 0.135774757188832 RNF25 other 0.964414852772235 1 1 3.21115478254016 -1.49988357869144 5.31364649446875e-05 284.559953014766 78.566565472606 3.62189630287433 0.00040113617909654 -254.781302471049 207.208682607586 -1.22958796545006 0.22080257027241 STK36 other 0.403571451254902 1 1 3.62189630287433 -1.22958796545006 0.796190954233166 1.46911057180551 21.7060111662085 0.0676821992099864 0.946128753501262 -48.088619737076 75.6403838506797 -0.635753248317815 0.525906029763133 ADORA1 other 1 1 1 0.0676821992099864 -0.635753248317815 0.150904341480314 -1.95578501638774 5.6446767339374 -0.346483086379243 0.72945264811073 -23.4087243774645 12.4672763374667 -1.87761334102433 0.062325052498702 NEK10 other 1 1 1 -0.346483086379243 -1.87761334102433 0.630199923466542 2.80407867439758 2.91393102595092 0.962300977416756 0.337387681140041 2.88793951805949 6.4199460401935 0.449838596769957 0.653451263045175 EOMES other 1 1 1 0.962300977416756 0.449838596769957 4.41239530647647e-12 156.131387117945 22.7318919648382 6.86838505828947 1.43136797433475e-10 -127.727447809238 79.8690309422883 -1.59921118739417 0.11178418741102 CWC22 essential 5.48946100078737e-08 1 1.85648426271216e-06 6.86838505828947 -1.59921118739417 7.00468786669177e-08 89.3267232092735 23.7834772554471 3.75583108600383 0.000243495700171028 -130.26390932953 53.1381644897891 -2.45141906161552 0.0153330845813226 AZI2 other 0.000706352724477198 1 1 3.75583108600383 -2.45141906161552 0.0512196396960614 221.880625474208 99.1371738378809 2.23811731648765 0.0266384082346957 18.3426838601937 218.862279129041 0.0838092517960982 0.933316235442229 TGFBR2 ts 1 1 1 2.23811731648765 0.0838092517960982 8.95004424348885e-05 137.613340687371 63.6704683714679 2.1613370249533 0.0323822393165281 -419.325378330864 159.072717763995 -2.63606094259977 0.00934089606719837 ANKZF1 other 0.660155263399738 1 1 2.1613370249533 -2.63606094259977 0.00715606660606887 64.4047221583187 30.4433152374105 2.11556204230919 0.0359702175667232 -58.8524581138501 57.9942424611778 -1.01479829059319 0.311773314434083 HDAC11 other 1 1 1 2.11556204230919 -1.01479829059319 0.986345108529799 -1.58589687422565 165.015775100805 -0.00961057737211398 0.992344187898996 -47.0547477094797 317.796096105437 -0.148065845635398 0.882480797194798 FBLN2 other 1 1 1 -0.00961057737211398 -0.148065845635398 1.37557638537106e-05 65.6486745492776 14.4771203888988 4.53465003990832 1.23454864477031e-05 5.6771726016064 36.1692782315179 0.156961180294146 0.875503202049059 GLB1L other 0.112054452352326 1 0.124306703041923 4.53465003990832 0.156961180294146 8.66435046134785e-10 461.66371104619 109.854317304779 4.20250858020768 4.44327488439611e-05 -742.225337387385 242.235249642421 -3.06406824969954 0.0025758062016637 STT3B other 9.81497620261484e-06 1 0.422466576008382 4.20250858020768 -3.06406824969954 5.4055215824143e-05 5.93902253349587 14.2779956764808 0.415956319644979 0.678009983443104 -102.774680267966 27.4413203282998 -3.74525274434321 0.000252580568757011 CHCHD4 essential 0.409846646378653 1 1 0.415956319644979 -3.74525274434321 0.410691080442526 29.6737090497612 43.4297707749768 0.683257326028959 0.495470913361919 -159.527681947396 162.710130423367 -0.980440993638873 0.328406227040851 NFASC other 1 1 1 0.683257326028959 -0.980440993638873 0.000251840721416286 64.2817679558011 18.029312398872 3.56540319085174 0.000486897543761812 -47.1321362799265 54.2595130842924 -0.868642816729787 0.386421046858668 SGO2 other 1 1 1 3.56540319085174 -0.868642816729787 0.00157663418831341 39.4934118267775 10.7687073993952 3.66742361566956 0.000341030889449482 11.4743207031087 61.0121167935241 0.188066261361491 0.85108231989044 SERPINI1 other 1 1 1 3.66742361566956 0.188066261361491 2.01887074909422e-13 226.777699789432 32.7317821845231 6.92836395253361 1.09062392836531e-10 -90.1425348440793 72.1498852117038 -1.24937877003658 0.213422152026401 CLASP2 other 2.61383195885228e-09 1 1.41955610516029e-06 6.92836395253361 -1.24937877003658 0.00310496535756039 223.349172828151 100.297320489805 2.22687078515577 0.0274066960638262 -768.701114442361 370.085536470437 -2.07709039854295 0.0394538780919428 NUAK2 other 1 1 1 2.22687078515577 -2.07709039854295 7.04573560491401e-09 1774.74464578391 271.500447535682 6.53680191650757 9.6961113263438e-10 494.497693681272 1606.3683735427 0.307835800197374 0.758643015379638 PRKCI other 7.58191608444797e-05 1 1.22432797717743e-05 6.53680191650757 0.307835800197374 0.0610214160366759 -0.208358422399522 11.2049345738687 -0.0185952377522524 0.985187612582234 -47.8306186963721 22.4293475252937 -2.13250156485529 0.0345207085633072 EFHB other 1 1 1 -0.0185952377522524 -2.13250156485529 0.0344170630835979 19.3596358118361 7.51209162749687 2.5771298823051 0.0109331958321456 -19.9011489269456 40.3270267905975 -0.493494078556411 0.622390130583862 EIF5A2 other 1 1 1 2.5771298823051 -0.493494078556411 0.150076760998707 -102.930040290932 56.757539433156 -1.81350427306938 0.0717664357653992 -228.317881623897 304.690481265064 -0.749343664022353 0.45483151980418 RPL22L1 other 1 1 1 -1.81350427306938 -0.749343664022353 0.0479610989680554 55.7389402261348 23.518488511101 2.37000520674725 0.0190429019425053 -78.535464095602 96.0051925642538 -0.818033504209059 0.414618575864671 PPM1L other 1 1 1 2.37000520674725 -0.818033504209059 0.0149439446478731 10.163654673424 14.8592274526307 0.683996170448592 0.494998916686062 -105.876949768491 43.989664204305 -2.40685969496738 0.0172664741162691 ICA1L other 1 1 1 0.683996170448592 -2.40685969496738 2.23870971832767e-06 1164.19874804382 224.137569881082 5.19412586056631 6.29984716316433e-07 -941.822574334888 986.901302616072 -0.954322962020934 0.341387228776587 SNHG16 other 0.0197700455225517 1 0.00697141087075765 5.19412586056631 -0.954322962020934 0.367480886928279 -2.47162199858378 2.29733540804166 -1.07586466909971 0.283648857245165 3.17863656846124 6.84418576260676 0.464428739767371 0.642988106012574 CTLA4 other 1 1 1 -1.07586466909971 0.464428739767371 0.496746171896831 -1.62111881209365 2.63358320879125 -0.615556328990151 0.539084386979599 5.61091560629141 7.84592995831391 0.715137101159797 0.475593233641314 ICOS other 1 1 1 -0.615556328990151 0.715137101159797 3.68043297648793e-10 268.353706460983 46.3172903634428 5.79381272857854 3.75801103931571e-08 -64.3064623140778 110.409257470836 -0.582437232050616 0.561123986784379 RYBP other 4.24795574146237e-06 1 0.000446119822280219 5.79381272857854 -0.582437232050616 2.1839382353071e-09 290.023822890478 67.0390678850081 4.3261911604731 2.71669821674347e-05 -363.4707572688 159.804981004734 -2.27446450657274 0.0243188214167004 PPP4R2 essential 2.42089553383792e-05 1 0.264389070453475 4.3261911604731 -2.27446450657274 0.395631250341699 -1.71949177457081 13.0149703452009 -0.132116457353655 0.895072841207471 -38.2466414428694 30.8570135606153 -1.2394796848288 0.217143081501391 CADPS other 1 1 1 -0.132116457353655 -1.2394796848288 0.0234161198545566 75.4812848139635 74.0920312836771 1.01875037714876 0.309929699647001 -160.815152866898 113.997109420163 -1.41069500520558 0.160364534763682 NKX6-1 other 1 1 1 1.01875037714876 -1.41069500520558 4.89045295055921e-09 186.61419303588 66.0625951291266 2.82480869349927 0.00536187922457936 -314.690674787061 102.087200485605 -3.08256738641232 0.00243487457524385 CDS1 other 5.31347713078258e-05 1 1 2.82480869349927 -3.08256738641232 1.11063791533725e-07 213.223628028598 59.5621254235142 3.57985257430757 0.000461049362841408 -154.928960346882 92.0419585027497 -1.68324276087904 0.0943674804648604 WDFY3 other 0.00110086430168229 1 1 3.57985257430757 -1.68324276087904 3.48965677379078e-18 79.2098433127151 11.4089546677017 6.94277833682298 1.04594032934671e-10 -105.680135118273 29.7255733668005 -3.55519248743252 0.000503756689366603 COX18 other 4.87470154730833e-14 1 1.36244187300702e-06 6.94277833682298 -3.55519248743252 0.168461385429371 -83.115375965215 131.905172068506 -0.630114609319858 0.529547426095321 -350.627033510758 197.617115417558 -1.77427462580807 0.0779809313248584 PTPN13 other 1 1 1 -0.630114609319858 -1.77427462580807 4.10653597546261e-05 -17.0403188334782 53.9008301657102 -0.316142047925613 0.752340112223753 -541.448529598122 129.49026411231 -4.18138408559048 4.94059222391178e-05 THOC7 essential 0.315628355074056 0.711050032865383 1 -0.316142047925613 -4.18138408559048 2.32870353268565e-06 99.2111880745727 33.5272168746102 2.95912387973081 0.0036007103832165 -190.394207378275 80.5556000745358 -2.36351299229487 0.0194200206845217 ATXN7 other 0.0205251929370913 1 1 2.95912387973081 -2.36351299229487 8.05140829031496e-10 139.960596098679 45.8147728211514 3.05492284432028 0.00267678982519034 -429.306633799504 110.078821355472 -3.89999300967409 0.000146266083109344 PSMD6 essential 9.13432270536232e-06 1 1 3.05492284432028 -3.89999300967409 3.76517515620714e-05 93.9343980625066 21.299963619783 4.41007316910449 1.99272209676011e-05 43.6692295571349 51.1772676322794 0.853293494895205 0.394894313887329 PRICKLE2 other 0.291048039574812 1 0.196601962066352 4.41007316910449 0.853293494895205 0.00510156324799348 376.252327431203 115.899216681416 3.24637506796484 0.00144979391640434 296.789694762767 278.470204755062 1.065786176384 0.288279638758912 ADAMTS9 other 1 1 1 3.24637506796484 1.065786176384 1.38355050672046e-05 90.9937499999999 29.5816654241518 3.07601849643356 0.002477966123756 -36.9458333333334 44.2495430931499 -0.834942707895506 0.405026815263518 PPM1K other 0.112690188772381 1 1 3.07601849643356 -0.834942707895506 4.09880660900394e-09 491.818258368742 74.3568032030425 6.61430073890829 6.08226474593317e-10 214.564864234636 291.399877655321 0.736324482910152 0.462675616645971 GMPS essential 4.4705683684406e-05 1 7.73116671855565e-06 6.61430073890829 0.736324482910152 0.00461740366172618 86.2480150359334 25.8682415309859 3.33412748340943 0.00107502319415704 27.9634187192297 102.068579444901 0.273966962911685 0.784481962480237 TIPARP other 1 1 1 3.33412748340943 0.273966962911685 0.00184096893395557 235.175129598863 68.3440487787246 3.44104766693414 0.000749606452144421 330.236360205286 267.832507625311 1.23299581194705 0.219493415204875 CCNL1 essential 1 1 1 3.44104766693414 1.23299581194705 0.771849278015224 -6.02452054947481 28.2068273338161 -0.213583770984844 0.831159769988381 -76.4910455426825 110.225201720233 -0.693952420580075 0.488778249793156 PTX3 other 1 1 1 -0.213583770984844 -0.693952420580075 0.000656068041566933 4.45341480057069 1.98023492377093 2.24893256204679 0.025926004094076 -7.639096520067 4.49692888840274 -1.69873633976461 0.0913752043804749 HESX1 other 1 1 1 2.24893256204679 -1.69873633976461 1.98570320205988e-08 151.717315716272 39.4627869783023 3.84456667492062 0.000177115363840026 -220.984032309832 92.6638018932485 -2.38479349859195 0.0183214966094703 SLMAP other 0.00020792298228769 1 1 3.84456667492062 -2.38479349859195 0.0265331178593114 -387.328894845097 285.966617474822 -1.35445492996818 0.177575209361384 -1335.30451660372 493.302889378363 -2.70686538707772 0.00755920108537481 RPL9 essential 1 1 1 -1.35445492996818 -2.70686538707772 1.88417846001496e-06 140.377677406686 90.4977591777974 1.55117296474591 0.122899666091351 -498.356688315028 155.340255615239 -3.20816189172113 0.00162334773919111 SMIM14 other 0.0167673041156731 1 1 1.55117296474591 -3.20816189172113 1.70965979153177e-14 105.532402588764 32.5634687597705 3.2408218966875 0.00146832916580253 -417.775126581782 76.7025836512742 -5.4466891034751 2.054367279133e-07 RPP14 essential 2.27059916913334e-10 0.00300184146826914 1 3.2408218966875 -5.4466891034751 0.000991433632395498 0.898276766080015 10.1906232738646 0.0881473823474354 0.929877109664693 -77.3969972531556 24.003804382409 -3.22436377251413 0.00154950919986651 ABHD6 other 1 1 1 0.0881473823474354 -3.22436377251413 0.000324872730293286 13.6001825862256 8.56818169452971 1.58728923721453 0.114538963523969 -49.5589459513825 20.1653206744173 -2.45763242507001 0.0151170670717828 C3orf67 other 1 1 1 1.58728923721453 -2.45763242507001 0.000668104541551449 165.140050694104 153.686137491481 1.07452795281069 0.284255992440865 -635.182385914751 263.365458726936 -2.41179078298694 0.0170432587775611 RBM47 other 1 1 1 1.07452795281069 -2.41179078298694 0.0548133117927328 110.556857164977 77.4977724759245 1.4265810955963 0.155724878920666 -88.7672106551622 131.275450485856 -0.676190485933442 0.49993396754572 APBB2 other 1 1 1 1.4265810955963 -0.676190485933442 0.0115256242596594 36.6949239361867 21.5899081933151 1.69963316229147 0.0912188888240316 -69.5931156848828 44.3539731251442 -1.56903904614197 0.118691273526657 IL17RE other 1 1 1 1.69963316229147 -1.56903904614197 1.15907582241381e-05 149.996206454741 39.9794916401619 3.75182875772388 0.000250858624260252 -97.7941720340745 83.3715913095952 -1.17299154901484 0.242670994864018 IL17RC other 0.095183306536622 1 1 3.75182875772388 -1.17299154901484 3.54486807856492e-06 184.70601121592 47.2143309110691 3.91207516132812 0.000140968042187477 -139.084613183997 98.628190651828 -1.41019126747428 0.160654635295893 CRELD1 other 0.0306170255945652 1 1 3.91207516132812 -1.41019126747428 3.0145241667938e-08 215.844599282116 45.4880895375641 4.74507945874208 5.02713292495862e-06 -155.88260087071 95.1657025560699 -1.63801240030637 0.103633124273108 PRRT3 other 0.000311611363121475 1 0.0523776979451438 4.74507945874208 -1.63801240030637 0.000151823661393103 3.62472551602988 2.46541729220864 1.47022799243153 0.143501235441257 -14.6582125603865 5.11316018681962 -2.86676185075747 0.00471642286716743 FANCD2OS other 1 1 1 1.47022799243153 -2.86676185075747 0.048355489089493 9.26387830889357 3.79181482885696 2.44312518596436 0.0156985293106139 12.5465070145369 16.0426646036649 0.782071265871302 0.435381336722223 PCOLCE2 other 1 1 1 2.44312518596436 0.782071265871302 1.21313129802685e-05 324.545191143042 70.0426711052426 4.63353532956214 7.78239335724409e-06 -311.996660804061 294.705427354667 -1.0586729386174 0.29146200799593 U2SURP essential 0.099355453308399 1 0.0797461847316802 4.63353532956214 -1.0586729386174 1.3715794255845e-11 243.487811401431 42.353957794814 5.74887977602991 4.6790444802666e-08 -185.0430923117 83.6002063480076 -2.21342865520463 0.0283384761661898 MTMR14 other 1.67771595337496e-07 1 0.000552875895788302 5.74887977602991 -2.21342865520463 0.000773349923189883 101.5052371519 27.4791142026076 3.69390499284246 0.000313584864464996 170.408987408065 127.359700384129 1.33801341314478 0.183015881898005 TTC14 other 1 1 1 3.69390499284246 1.33801341314478 0.634872827928349 -8.68681037233595 10.7114883327346 -0.810980706181493 0.418653153318988 0.228409160886535 23.1682849802716 0.00985869955765096 0.992147036367356 CXCL3 other 1 1 1 -0.810980706181493 0.00985869955765096 0.755850659506057 -19.9147548830257 27.017455434028 -0.737106976326994 0.462201071822896 -28.9628643725263 58.4370805898591 -0.495624765648412 0.620879725142934 CXCL5 other 1 1 1 -0.737106976326994 -0.495624765648412 3.96619829604289e-24 87.972896122163 8.64617633173803 10.1747746919336 7.20260136264334e-19 -121.852591516229 35.0415904571828 -3.47737045968621 0.000660500047356312 MTHFD2L other 5.69784047209522e-20 1 1.0275231103947e-14 10.1747746919336 -3.47737045968621 0.233945094033162 -108.362964580219 73.6340167674004 -1.47164271810028 0.143198425721997 -240.899635557496 159.265811782264 -1.51256338608838 0.132480725143565 CXCL1 other 1 1 1 -1.47164271810028 -1.51256338608838 8.82156337579951e-40 145.700434370025 8.98269612131205 16.2201228230732 3.86485641899566e-35 -99.4216940461768 36.2695101136206 -2.74119208488675 0.00684620558326816 RCHY1 other 1.28477249005144e-35 1 5.62220663271299e-31 16.2201228230732 -2.74119208488675 0.58355701215019 -1.60756279485808 2.03609550317804 -0.78953211789374 0.431030947848401 4.96662482747346 8.14623955225344 0.609683129941788 0.54298204937153 CPA3 other 1 1 1 -0.78953211789374 0.609683129941788 0.0466511702917035 108.489360003194 46.0534051993511 2.35572938707957 0.0197715277266911 186.20908026244 181.582217708364 1.02548081311303 0.306776356434713 GYG1 other 1 1 1 2.35572938707957 1.02548081311303 0.00396591934967627 765.663725181211 247.702506047638 3.09106168281543 0.00237030169700794 -1183.11760689148 1019.25787597412 -1.16076376232144 0.247545881795004 HPS3 other 1 1 1 3.09106168281543 -1.16076376232144 0.0771914624576787 -8.99992288139775 4.31454064482015 -2.0859515814743 0.0386536955511273 -18.7672128720201 17.5805785412897 -1.06749688742856 0.287440029166879 TM4SF18 other 1 1 1 -2.0859515814743 -1.06749688742856 6.01603435314823e-09 313.75355398581 48.0737489957566 6.52650480854955 9.3394100758046e-10 58.6606365254757 189.306459319199 0.309871288789808 0.757080487918916 TOPBP1 essential 6.49912191170603e-05 1 1.17966088667488e-05 6.52650480854955 0.309871288789808 3.07637278446384e-08 278.022131492044 46.4488852354056 5.98555013932007 1.45837038291861e-08 -139.562077454218 178.425812981275 -0.782185464772772 0.435306593005978 RYK other 0.000317789308635115 1 0.000176229477071885 5.98555013932007 -0.782185464772772 1.07625656289871e-05 54.8362367823337 21.1846224649149 2.58849251966379 0.0105566328558929 -131.442342175902 46.6782768872289 -2.8159210438178 0.00549630053178407 SNRK other 0.0886727782172246 1 1 2.58849251966379 -2.8159210438178 0.952912174683837 3.80246835443038 12.2410727056744 0.31063195570007 0.756539144358088 2.65879746835443 46.1064731138004 0.0576664682590655 0.954095945859323 TCF23 other 1 1 1 0.31063195570007 0.0576664682590655 0.0147546691129979 3.51483321878053 1.86535212927718 1.88427330347676 0.0616013423816424 -13.1172615191347 6.92185318614776 -1.89505052568658 0.060147434256695 UCN other 1 1 1 1.88427330347676 -1.89505052568658 3.89852210029669e-05 68.9343499955714 16.3678239753905 4.21157693895147 4.60506594053466e-05 -80.524993356757 62.524230625984 -1.28790058750906 0.199983825122848 ZNF513 other 0.300498083490869 1 0.437435213691387 4.21157693895147 -1.28790058750906 1.22948850400745e-08 136.41059671423 21.7293916118778 6.27769976954461 3.81392186481325e-09 -7.08541994902511 83.99772252199 -0.0843525245243429 0.932893309455134 SLC4A1AP other 0.00013042414050511 1 4.71934691551991e-05 6.27769976954461 -0.0843525245243429 0.915778146450472 0.155727476915386 21.7228957441383 0.00716881758075036 0.994290151370213 -33.5201231178771 82.375766050175 -0.406917285569886 0.684677153931803 PLB1 other 1 1 1 0.00716881758075036 -0.406917285569886 0.00011966369676381 185.252807400286 43.1446271594546 4.2937630846971 3.18657831861209e-05 -22.5928979395037 175.332385670505 -0.128857528819357 0.897647722385293 SPDYA other 0.869715748079371 1 0.308046526060231 4.2937630846971 -0.128857528819357 8.20166039046738e-18 242.951515484296 32.6874593767888 7.43256037992401 6.88964521022037e-12 -236.184109378433 71.9710178029919 -3.28165581908186 0.00127674533498484 KIAA1143 other 1.14093297691792e-13 1 9.21834529127486e-08 7.43256037992401 -3.28165581908186 0.000760901879094342 52.3855143557928 21.8865023558529 2.3935078115295 0.0178997356351011 -87.973559888868 48.1536626269985 -1.82693392546932 0.0696584775516691 KIF15 other 1 1 1 2.3935078115295 -1.82693392546932 9.71265931218558e-10 269.664100679092 41.4812302892954 6.50087036470277 1.09909458300205e-09 -203.910990818507 175.453069572405 -1.16219677042674 0.246989154642706 WDR43 essential 1.09714199590448e-05 1 1.38463935566598e-05 6.50087036470277 -1.16219677042674 4.39330176200283e-08 129.018186856776 55.6074862476521 2.32015858947812 0.0216366038790463 -522.079782359056 122.525744528585 -4.26098028922613 3.51984364313125e-05 ZDHHC3 other 0.000448731841970969 0.507667048648821 1 2.32015858947812 -4.26098028922613 0.0180346293460142 -216.219782789533 112.291045056651 -1.92553006057117 0.0559938812716744 -673.202331692235 247.779134887855 -2.71694520201197 0.00733817629947268 CDCP1 other 1 1 1 -1.92553006057117 -2.71694520201197 0.451294444125837 -3.22162500847921 4.64383907278345 -0.693741742120321 0.488882536155061 -12.7624376555265 10.247000795408 -1.245480303002 0.214834733361421 CLEC3B other 1 1 1 -0.693741742120321 -1.245480303002 0.967094325855701 7.41307297114928 29.7182288161791 0.24944531576907 0.803346597469694 2.3266279181854 65.5756389368115 0.0354800647909406 0.971742593568038 SLC6A20 other 1 1 1 0.24944531576907 0.0354800647909406 1.30214597614468e-15 379.051574406827 49.4211897915317 7.66981887740342 1.73722573669101e-12 -192.149281341658 110.031122152808 -1.74631756526855 0.0827241874959024 LZTFL1 other 1.76453801227366e-11 1 2.35081386689028e-08 7.66981887740342 -1.74631756526855 1.37235933719217e-06 200.136066095357 46.3918681866683 4.3140333407153 2.83392546745424e-05 -135.540618496477 103.286653698065 -1.31227621036789 0.191354522474308 FYCO1 other 0.0123667235556301 1 0.275145823635132 4.3140333407153 -1.31227621036789 0.153973025089534 -31.6766989374606 20.6742995327856 -1.53217761439642 0.127517102747199 21.9901662442169 45.3633878469367 0.484755819349632 0.628533913905558 CCR1 other 1 1 1 -1.53217761439642 0.484755819349632 0.537499906172158 -9.03212346300101 8.09304799493843 -1.11603483244507 0.266156942408362 -8.91077637867489 17.6843459760734 -0.503879328686003 0.615070947919374 LRRC2 other 1 1 1 -1.11603483244507 -0.503879328686003 3.21535092569522e-06 74.336021917271 19.9992428292121 3.71694181385164 0.000301104392688574 -85.9795965898296 45.6511321673095 -1.88340556976151 0.0619323528055038 ELP6 essential 0.027893169280406 1 1 3.71694181385164 -1.88340556976151 0.00673087727512796 404.459780482051 156.079256972998 2.59137433331081 0.0104723435290046 -1108.6540788433 717.966874658164 -1.5441577013858 0.124589355579364 DTX3L other 1 1 1 2.59137433331081 -1.5441577013858 8.52033381115807e-20 470.817924663421 43.9526659144442 10.7119310027721 2.49672055790668e-20 -27.7191844963974 180.465846586098 -0.153597952303806 0.878129153406082 ZNF148 other 1.20230430409252e-15 1 3.57730121536869e-16 10.7119310027721 -0.153597952303806 5.0559039107334e-05 30.5749794836185 8.93664807909088 3.42130284341787 0.000801934735918606 -83.8048181932962 36.5609608374226 -2.29219408554264 0.0232760531080059 NMNAT3 other 0.384754287606811 1 1 3.42130284341787 -2.29219408554264 1.09324659094224e-05 60.4766327583667 34.8530097663129 1.73519111158142 0.0847205445891954 -383.236051358342 108.137193081811 -3.54398001683293 0.000523023481568323 SMIM12 other 0.0899960593663655 1 1 1.73519111158142 -3.54398001683293 2.3483531646523e-08 78.8795482696196 19.2052687154127 4.10718274440579 6.5817255441492e-05 -153.840375189236 58.0897417227308 -2.64832258892687 0.0089605394561567 ZMYM6 other 0.000244487047971951 1 0.613943358758237 4.10718274440579 -2.64832258892687 0.000126049146887117 126.570143692938 32.8639341636252 3.85133876737829 0.00017441275492468 -201.143036406739 136.092726045962 -1.47798521089811 0.14153672474511 TPRA1 other 0.912721872609614 1 1 3.85133876737829 -1.47798521089811 2.24410084255757e-10 508.538174561859 70.617012588022 7.20135496992288 2.85864932727036e-11 111.997061715541 308.375928525394 0.36318354111196 0.716989507295301 YEATS2 essential 2.61505071183234e-06 1 3.77741922105505e-07 7.20135496992288 0.36318354111196 0.00281403249688758 275.734022978819 82.1203636225787 3.35768146675629 0.00099931612199222 93.0809315130065 301.28051046458 0.308951054847437 0.757793245355414 GRIK3 other 1 1 1 3.35768146675629 0.308951054847437 9.57725896029884e-13 429.353890001791 66.2862664520427 6.47726766014833 1.22438599624205e-09 -661.02945228905 263.017958377515 -2.5132483590351 0.0130048648164919 MEAF6 other 1.21688652349557e-08 1 1.54040002187213e-05 6.47726766014833 -2.5132483590351 4.34689854895932e-17 111.734681845572 13.3426568423708 8.37424533701178 3.41200624237524e-14 -111.941212683832 52.9424653076687 -2.11439365419233 0.0361134232508218 SNIP1 essential 6.00194762637078e-13 1 4.71334542321716e-10 8.37424533701178 -2.11439365419233 0.0266813622311207 206.827322030585 104.416593882798 1.98078978004912 0.0494193875198925 -453.982830898519 414.315676742135 -1.09574137881602 0.274925072209887 DNALI1 other 1 1 1 1.98078978004912 -1.09574137881602 0.00130624707195192 220.288414751265 61.8123989391622 3.56382244552715 0.000517042544198557 -201.419248991613 252.516237965148 -0.7976487001973 0.426575048521822 POLR2H essential 1 1 1 3.56382244552715 -0.7976487001973 9.89031439082494e-06 71.1236870310826 14.6532287798287 4.85378943437979 2.96075161540696e-06 -20.854893231099 60.1792869996039 -0.346546033874352 0.729408532873452 KLF15 other 0.0817632290689498 1 0.0313780456200829 4.85378943437979 -0.346546033874352 0.253560941609205 -24.0630582350839 17.418507585312 -1.3814649801212 0.169150109993502 -81.4754582680629 71.5359995282567 -1.13894345232263 0.256506853569999 CFAP100 other 1 1 1 -1.3814649801212 -1.13894345232263 0.976388747919447 -2.43792915106117 11.2690133025537 -0.216339184772166 0.829076024769406 0.30560432272161 45.8615614618334 0.00666362664027343 0.994693857637785 CAMK2N2 other 1 1 1 -0.216339184772166 0.00666362664027343 0.291915515907316 -2.40900408553082 12.1242025418347 -0.198693817363948 0.842771315448754 78.4101389552124 51.110658893741 1.53412498786656 0.127105422488487 LIPH other 1 1 1 -0.198693817363948 1.53412498786656 2.10430709197718e-10 233.990582055499 32.5428640978135 7.19022706029185 2.85005219221075e-11 161.958846972403 137.187350721792 1.18056691174718 0.239643473954985 TMEM41A other 2.45593680704656e-06 1 3.76634397200651e-07 7.19022706029185 1.18056691174718 0.000795791925736907 1354.10746934847 374.28114344799 3.61788856599621 0.000403698443465865 -1274.90769810162 1527.18497521779 -0.834808958174705 0.405135446628668 RPN1 essential 1 1 1 3.61788856599621 -0.834808958174705 3.12079930311712e-15 297.670137143258 32.5561990735315 9.14327057869808 3.83608117919167e-16 40.2958927172605 137.243752450776 0.293608211650384 0.769460459895593 SENP2 other 4.19934754227439e-11 1 5.395831786651e-12 9.14327057869808 0.293608211650384 0.000181226311108467 39.862834835906 10.6324604869588 3.7491636940292 0.000253305375687927 -90.1432659878065 74.3944090065929 -1.21169409356848 0.227547578192209 HEYL other 1 1 1 3.7491636940292 -1.21169409356848 0.0226718929292698 194.068888549997 78.1109038037896 2.48453006045722 0.0140711710488738 -289.049249282556 322.069915890393 -0.897473607503674 0.370904469387459 IFT122 other 1 1 1 2.48453006045722 -0.897473607503674 1.40117860870712e-08 199.4752971463 31.2529567463116 6.38260561282226 2.14369961177969e-09 35.8794910675934 129.084403316599 0.277953727528132 0.781438436198799 RFC4 essential 0.000148132602512517 1 2.67662333526812e-05 6.38260561282226 0.277953727528132 0.000226438465454348 150.740316426878 36.3225431022976 4.15004852502585 5.53314405440028e-05 -12.2777409968023 148.807014619872 -0.0825078107249568 0.934352177750961 RPL39L other 1 1 0.520447529756891 4.15004852502585 -0.0825078107249568 1.01864917566953e-14 411.085423758212 76.0772816004605 5.40352408905898 2.66527568060991e-07 -662.57205732498 172.239553497377 -3.84680547453387 0.000179673964223666 BAP1 other 1.35857240559045e-10 1 0.00301922429099491 5.40352408905898 -3.84680547453387 0.000144666421798169 778.608792715971 383.237061227488 2.03166361369678 0.0439412672557761 -1981.29690697059 871.524816289189 -2.2733683194549 0.0244140627185081 TKT essential 1 1 1 2.03166361369678 -2.2733683194549 3.34061437432014e-10 550.993444223725 119.740242460647 4.60157281212128 8.82286519169384e-06 -641.06516642876 272.302977375648 -2.3542348769268 0.0198482975311504 PRKCD other 3.86442270821354e-06 1 0.0900461621464274 4.60157281212128 -2.3542348769268 4.96763750200673e-15 131.955262719942 28.1478676774447 4.68793104444212 6.11974595320032e-06 -283.84771056175 64.2154305926309 -4.42024148934575 1.87347551789162e-05 RFT1 essential 6.66408570894203e-11 0.271279254990707 0.0633148916318105 4.68793104444212 -4.42024148934575 2.39752063611499e-07 112.330913173653 27.7104779866783 4.05373423106072 8.02274783477375e-05 -100.257829341317 63.2635365680368 -1.58476485476741 0.115098086817914 SFMBT1 other 0.00230929187670596 1 0.741622809846485 4.05373423106072 -1.58476485476741 5.15685762712592e-15 438.02458639706 71.7558206902417 6.10437706911529 9.58448716587728e-09 -506.845632423643 161.515451543593 -3.13806281429888 0.00207406686710203 GNL3 essential 6.91534607797585e-11 1 0.000116758222654717 6.10437706911529 -3.13806281429888 4.77150093379364e-16 510.25042990358 61.3514356518973 8.3168457996435 8.03306399282464e-14 -29.4395432070568 139.985375259371 -0.210304420390416 0.833742539701346 PBRM1 other 6.50967256042191e-12 1 1.1054299360526e-09 8.3168457996435 -0.210304420390416 4.54956690257195e-07 92.2644856974395 18.6174003099935 4.95582004797487 2.03473647806404e-06 18.097738629122 33.328384937567 0.543012770136445 0.587978377534151 UVSSA other 0.00427750280179815 1 0.0218184792542807 4.95582004797487 0.543012770136445 6.41214239054468e-20 585.379899713812 62.4878351740904 9.36790173772142 8.74164140115191e-17 -45.9047719645106 140.595709874734 -0.326501939535781 0.744487926961581 FAM208A other 9.05522748392719e-16 1 1.23458201508468e-12 9.36790173772142 -0.326501939535781 5.01954347619957e-08 568.924539420632 106.061555572031 5.36409763511579 2.90858574794009e-07 11.1371192854039 240.855904254303 0.0462397603242682 0.963178673650631 ARHGEF3 other 0.000510286789790448 1 0.00328612017802271 5.36409763511579 0.0462397603242682 6.76873075772609e-06 508.547380691167 122.414661580251 4.15430124240291 5.56880903766336e-05 -5.82707076247935 218.847782505155 -0.0266261357358834 0.978794791046749 SLBP essential 0.0567896510573219 1 0.523690801901862 4.15430124240291 -0.0266261357358834 5.46769369530919e-07 362.068199732767 164.671838039991 2.19872568401671 0.029439494460686 -909.712344634669 305.37270083134 -2.97902314829744 0.00337717638429345 LRPAP1 other 0.00510135821772347 1 1 2.19872568401671 -2.97902314829744 0.00381198406999268 14.7910083861895 4.47121638302752 3.30805023043288 0.00118305125972597 -0.30080696538543 16.5328466776114 -0.0181945052325913 0.985508526815488 ZDHHC19 other 1 1 1 3.30805023043288 -0.0181945052325913 0.000673798201436688 17.308043248726 4.69519526094129 3.68633087375711 0.000320052886856801 -9.0765997954789 17.463886697653 -0.519735380366314 0.604035119593 SLC51A other 1 1 1 3.68633087375711 -0.519735380366314 4.01656038006083e-11 331.183168431833 44.4569165242168 7.44953078901523 7.73777878359565e-12 86.3394507037786 164.985925808668 0.523314035913012 0.601554560038023 UBXN7 other 4.83272544928919e-07 1 1.03376724548838e-07 7.44953078901523 0.523314035913012 2.81837758139418e-11 138.678240393651 18.2547464931907 7.59683189494746 3.44050824695829e-12 114.534006314478 67.7459546466971 1.69063978671178 0.0930541308057287 RNF168 essential 3.40939136021253e-07 1 4.62885979545769e-08 7.59683189494746 1.69063978671178 1.2809178556329e-07 137.432082467277 23.548574206458 5.83611055439559 3.35619991122707e-08 10.2665580585359 88.1203282119484 0.116506125962702 0.907412639654144 PIGX other 0.00126298500565404 1 0.000399253541439573 5.83611055439559 0.116506125962702 0.185839724083771 107.72379325933 58.5400878741745 1.84017136241528 0.0678162399897957 116.354211663067 221.948623031848 0.524239394115867 0.600923684569795 MELTF other 1 1 1 1.84017136241528 0.524239394115867 0.472815634208037 -7.59859625668455 29.2126364184954 -0.260113334100637 0.795123799964184 -62.7868032702592 55.6595503283314 -1.12805085380469 0.261052809750589 S100P other 1 1 1 -0.260113334100637 -1.12805085380469 0.12662684738106 -4.61529649564876 14.108351994941 -0.32713221907872 0.744020936060912 -48.8648083193474 26.7674655985035 -1.82552988214466 0.0698968920364056 ABLIM2 other 1 1 1 -0.32713221907872 -1.82552988214466 3.43818727275098e-21 53.8704759929482 4.87030326331568 11.0610105942917 3.599771427439e-21 -23.0615320798666 34.0512286387549 -0.677259911074677 0.499284255988216 EXO5 other 4.88978993930644e-17 1 5.16891179265967e-17 11.0610105942917 -0.677259911074677 0.0508348185862727 23.3132841665029 9.50741269191385 2.45211656651142 0.0153570490529123 41.6163794313302 42.3095860667103 0.983615849271435 0.326898920426195 CLDN19 other 1 1 1 2.45211656651142 0.983615849271435 7.4364175283343e-08 40.2046900172214 8.58375387145557 4.68381207328394 6.2583325557035e-06 -86.5092355980224 38.2350395006564 -2.26256430561651 0.0250985034347528 C1orf50 other 0.000748177967525714 1 0.0646798669631957 4.68381207328394 -2.26256430561651 4.08769245472095e-07 106.740517253677 23.2144368424529 4.5980231171698 8.99638577352345e-06 -187.21642344617 102.055122536112 -1.83446375638738 0.0685664999098027 ERMAP other 0.00385878167725657 1 0.0917091565752981 4.5980231171698 -1.83446375638738 3.23789480630713e-09 93.8781472446899 15.5758033883395 6.02717849629314 1.23959266185366e-08 -64.6704611917091 68.4742229235751 -0.944449727657203 0.346458666533869 ZNF691 other 3.55650365524776e-05 1 0.000150300610249756 6.02717849629314 -0.944449727657203 1.2159119201666e-12 119.600775193798 44.1215327458683 2.71071215686627 0.00746117712212911 -258.628391472868 66.3257683943008 -3.89936517486455 0.000142613431322713 AIMP1 other 1.54019562927503e-08 1 1 2.71071215686627 -3.89936517486455 0.000141000317408724 -100.558139534883 78.719593669701 -1.27742198412271 0.203339087515079 -466.370639534883 118.335361736022 -3.94109277812701 0.000121815798329453 SGMS2 other 1 1 1 -1.27742198412271 -3.94109277812701 1.03604912096403e-13 292.443496309963 62.1138475567861 4.70818517630234 5.48097597535959e-06 -187.344620093929 93.1960667966 -2.01022024355177 0.0461312725387817 METAP1 essential 1.3511116586492e-09 1 0.0569308974560601 4.70818517630234 -2.01022024355177 3.1495521699843e-15 96.2310964083176 27.5009193155832 3.49919561975475 0.000612448527808343 -160.137386426002 41.204452228737 -3.88640978739473 0.000151530167955611 DNAJB14 other 4.23772244471388e-11 1 1 3.49919561975475 -3.88640978739473 9.88801503700659e-06 458.099979190553 298.872895612849 1.5327585268353 0.12741408680964 -1073.19173660953 436.058111644807 -2.46112091014994 0.0149691006275209 H2AFZ essential 0.0817541083259705 1 1 1.5327585268353 -2.46112091014994 0.291162914251002 -14.9494035129789 12.9594954851738 -1.15354826351702 0.250449725910756 -29.9911426173492 19.0575098448195 -1.57371780791717 0.117578616307692 EMCN other 1 1 1 -1.15354826351702 -1.57371780791717 3.85926139989536e-08 14.3632887189292 6.45634791483968 2.22467700136105 0.0275289390527132 -24.9624760994265 9.52630433713018 -2.62037356943674 0.0096458598709687 SLC9B1 other 0.000395883034401266 1 1 2.22467700136105 -2.62037356943674 8.87757985025767e-15 64.9565009560229 18.5353052820648 3.50447429743045 0.000596364498479693 -96.2891969407264 27.3487366894711 -3.52079140013062 0.000563381289761077 SLC9B2 other 1.18568956480041e-10 1 1 3.50447429743045 -3.52079140013062 4.02185874860478e-10 153.214149139579 42.4025144663164 3.61332697053353 0.000406520454872563 -117.489722753346 62.5646670213133 -1.87789256056173 0.0622503960473843 BDH2 other 4.63398565014242e-06 1 1 3.61332697053353 -1.87789256056173 1.14651525313287e-11 252.912483583209 82.4448597058971 3.06765618239167 0.00254424368539789 -412.288430640128 121.781632114373 -3.38547302644886 0.000899031464823203 PGRMC2 other 1.40746212474591e-07 1 1 3.06765618239167 -3.38547302644886 0.126018834454766 24.6390568108845 24.2030985393379 1.01801249831042 0.310622762993014 -65.5079764265988 54.767979220623 -1.19609993574369 0.233903555795198 CDC25A other 1 1 1 1.01801249831042 -1.19609993574369 6.52119917600238e-05 101.883972925791 26.4280505885792 3.85514522095776 0.000182790358715722 -36.4893510152828 59.1392083734229 -0.617007768938636 0.538334191592563 ZNF589 other 0.489676846126019 1 1 3.85514522095776 -0.617007768938636 1.75753988467207e-06 1371.35678969242 397.950031930577 3.44605271933149 0.000763288500386386 -2070.18216783611 884.749849415603 -2.33985026299073 0.0207914162566187 PLXNB1 other 0.0156790133111596 1 1 3.44605271933149 -2.33985026299073 0.000163686307380057 -4.93529209359272 66.0868962634093 -0.0746788300349531 0.94058245792387 -573.916115941714 145.397969809723 -3.94720859371543 0.000127483444476971 CCDC51 other 1 1 1 -0.0746788300349531 -3.94720859371543 1.46230510458288e-08 25.0315668895066 9.87121215617886 2.53581490231047 0.0123754290709153 -94.0145963666019 21.9600209646729 -4.2811706108042 3.53317159550894e-05 ATRIP essential 0.00015439017294186 0.5095540075043 1 2.53581490231047 -4.2811706108042 0.000672712530775095 729.054108659277 335.42186368517 2.17354378945188 0.0315101129205999 -1495.5893471604 742.803562954132 -2.01343857481302 0.0460864427487043 SHISA5 other 1 1 1 2.17354378945188 -2.01343857481302 0.000821077552233176 473.853081388644 320.306885651029 1.4793721353368 0.141057405789009 -872.548767828994 484.153390720932 -1.80221554687394 0.0734421550027802 SPRY1 other 1 1 1 1.4793721353368 -1.80221554687394 3.503209367272e-11 271.143998617889 37.4350806650915 7.24304566199941 3.95620891675386e-11 65.7322408080408 81.8032767524283 0.80354043771345 0.423187817377736 BSN other 4.22276857130967e-07 1 5.21349211049823e-07 7.24304566199941 0.80354043771345 8.07799489238066e-09 340.940811724914 102.751650077447 3.31810546563423 0.00117800172491387 -828.188028466743 219.282665676967 -3.77680573113234 0.000241447982101395 APEH other 8.66122612361054e-05 1 1 3.31810546563423 -3.77680573113234 2.10360528167548e-12 169.073073945026 28.814524149096 5.86763373464662 2.56403667868591e-08 -13.9984998064267 42.3052965885183 -0.330892368929189 0.741169812059731 INTU other 2.64423183906608e-08 1 0.000306633146404048 5.86763373464662 -0.330892368929189 1.86717397135566e-12 351.714388006774 54.6034619738085 6.44124704355704 2.10555453585243e-09 -221.87398702022 117.826596199737 -1.88305521992764 0.0619273495984608 RNF123 other 2.35058531253963e-08 1 2.63004817073327e-05 6.44124704355704 -1.88305521992764 0.0102065828374503 -11.0381477794371 26.3655721279733 -0.418657623883909 0.676042192062569 -100.077698965765 38.7097611894755 -2.58533496179188 0.0106436735930725 HSPA4L other 1 1 1 -0.418657623883909 -2.58533496179188 1.08768268325408e-12 73.3397887323942 16.0505342106679 4.56930515643831 9.93065787790164e-06 -49.8244466800804 23.8835086444183 -2.0861443526525 0.0386035047918945 MFSD8 other 1.3792904106345e-08 1 0.100875622723725 4.56930515643831 -2.0861443526525 7.42924185720653e-18 122.257446202081 16.4984250999349 7.41024949118101 7.79977151271278e-12 -12.3251531993729 24.3632370330618 -0.505891445485966 0.613656237177397 ABHD18 other 1.03407617410458e-13 1 1.0419714763833e-07 7.41024949118101 -0.505891445485966 0.000772767839435411 20.608072163756 14.1184828713877 1.45965202858446 0.146658390124972 -81.2396181077576 30.4024311500019 -2.67214216214918 0.00844457096167292 MON1A other 1 1 1 1.45965202858446 -2.67214216214918 0.0169090671347234 -69.4303226552562 42.963783861452 -1.61601973604449 0.108373902702526 -264.648502370765 92.5172692200868 -2.86053084577323 0.00488746382243586 MST1R other 1 1 1 -1.61601973604449 -2.86053084577323 4.6784308587406e-11 186.605797367897 33.6177710111414 5.55080815161879 1.42226184903934e-07 -179.165724441176 77.6534052444838 -2.30724877907274 0.0225400306024158 RAD54L2 other 5.61130997197347e-07 1 0.00163944123338765 5.55080815161879 -2.30724877907274 7.49950171229574e-06 -18.4863688123785 80.5970139596805 -0.229367912086998 0.818922571341572 -882.222720878826 187.972452795571 -4.69336175465182 6.40289473134386e-06 TEX264 other 0.0626658363079432 0.093104492288471 1 -0.229367912086998 -4.69336175465182 0.339340565855412 4.17067452609015 5.61007863758112 0.743425323515323 0.458488023323139 -11.0343626498761 13.0841105653083 -0.843340676066511 0.400497350069052 GRM2 other 1 1 1 0.743425323515323 -0.843340676066511 0.0199985339009202 -29.5501097293344 53.3670946055543 -0.553714043227284 0.580651578705614 -335.315390555149 122.575549518227 -2.73558137714313 0.00702769034240262 DUSP7 other 1 1 1 -0.553714043227284 -2.73558137714313 0.000684069894832349 31.2932638875188 22.5155097434857 1.38985367171501 0.16674836672841 -135.273705946955 51.4750385749423 -2.62794763621228 0.00953474477636948 POC1A other 1 1 1 1.38985367171501 -2.62794763621228 0.00647892763813302 34.3362071800132 21.3959658992266 1.60479818213089 0.110759982642985 -86.4056661471383 48.9155334504245 -1.76642591938018 0.0794731206937039 PPM1M other 1 1 1 1.60479818213089 -1.76642591938018 2.49436049653727e-12 756.712490382148 123.0481274474 6.1497278022831 7.4479788584041e-09 -514.749080960928 281.313067262972 -1.82980863978046 0.0693758366687967 WDR82 essential 3.12942467895566e-08 1 9.11707092057246e-05 6.1497278022831 -1.82980863978046 0.10888347722734 -25.5502587350213 20.3998848133555 -1.25247073543738 0.212272743597946 -64.8059771297619 30.6781879814237 -2.11244474963787 0.0362406732064456 PITX2 other 1 1 1 -1.25247073543738 -2.11244474963787 2.17521906710825e-06 419.531246155957 162.431055043466 2.58282657859787 0.0107302473789766 -447.132502258099 241.917025275029 -1.84828869216528 0.0664784588373746 C4orf3 other 0.0192366248741952 1 1 2.58282657859787 -1.84828869216528 0.023183208877243 179.04485574306 89.268534980547 2.00568829523276 0.0466295396959323 -20.2436309199776 133.24830807129 -0.151924112305778 0.879444357108928 PRSS12 other 1 1 1 2.00568829523276 -0.151924112305778 0.000102828114468239 49.0707131192161 15.0274866971979 3.26539720899344 0.00134550687735234 -2.89469243331516 22.4310523008112 -0.12904844563224 0.89748661702193 NDST3 other 0.753113110365386 1 1 3.26539720899344 -0.12904844563224 1.60826797004306e-07 1212.67280744118 266.040373705035 4.55822847695178 1.06294051892768e-05 53.4808790511944 410.023164325776 0.130433799122389 0.896397987073156 HMGB2 other 0.00157369020868713 1 0.107675874567374 4.55822847695178 0.130433799122389 4.309558545016e-06 46.8197731219141 20.0456687074036 2.33565533808417 0.020833722188813 -61.4180027797549 30.8945157457515 -1.98799046682584 0.0486327134557516 SAP30 other 0.0369199880551521 1 1 2.33565533808417 -1.98799046682584 0.660818385495177 2.16330895939838 10.6080121658143 0.20393160618442 0.838681532550354 -8.80890906868552 16.4124686884072 -0.536720540701328 0.592250568784549 HAND2 other 1 1 1 0.20393160618442 -0.536720540701328 6.87341224569995e-09 267.804593070104 62.6880621080875 4.27201901070658 3.34551926778827e-05 -101.379973307816 94.3444704423739 -1.0745724983399 0.284214865064956 MAD2L1 essential 7.40403967106799e-05 1 0.322340781451399 4.27201901070658 -1.0745724983399 0.0399299828432254 199.815076326389 421.154070571194 0.474446503759036 0.635836601801643 -1038.16436278653 634.483956519156 -1.63623422171619 0.103781002790424 ANXA5 other 1 1 1 0.474446503759036 -1.63623422171619 2.94644630554057e-17 201.818580833943 36.7717024192227 5.48842092033358 1.5953705473803e-07 -162.851865398683 58.4356687841187 -2.78685721900974 0.00597915103867754 MAP9 other 4.07640846371538e-13 1 0.00183324029599471 5.48842092033358 -2.78685721900974 0.00231507912266538 18.0133160499637 47.5329755330409 0.378964620833433 0.705226150638371 -182.141998585908 74.3572164252035 -2.44955375338889 0.0154025607231465 GUCY1A3 other 1 1 1 0.378964620833433 -2.44955375338889 6.27239615204341e-09 68.1985969600802 21.7309353352527 3.13831852646702 0.0020390598854138 -76.0530872445856 33.4994113750604 -2.27028130115759 0.0245866006048864 FBXO8 other 6.76728820843963e-05 1 1 3.13831852646702 -2.27028130115759 1.68285473779599e-13 86.903624519793 18.8870359835071 4.60123147939575 8.75697192291921e-06 -68.1267468403764 29.1153868117529 -2.33988809013095 0.0205814487489045 CEP44 other 2.18316745134273e-09 1 0.0894086833330051 4.60123147939575 -2.33988809013095 0.119393473851601 424.517252679729 220.398940355151 1.92613109661808 0.0559300824452893 229.583109169113 338.164570968323 0.678909409438456 0.498214289059001 HPGD other 1 1 1 1.92613109661808 0.678909409438456 0.00244050578132083 20.3499136227103 28.5023708825904 0.713972662363335 0.47631096066584 -95.8859819774953 43.82155673958 -2.18810076847157 0.03014978521187 TMEM144 other 1 1 1 0.713972662363335 -2.18810076847157 0.602847916687447 -57.8474390777757 66.3147652701942 -0.872316125105487 0.384368043546321 -98.9000291842984 104.231229754231 -0.948852176238325 0.344154064005577 FAM198B other 1 1 1 -0.872316125105487 -0.948852176238325 0.339335344317198 -70.7641645326503 142.062796873601 -0.498118902977901 0.619106269695617 -296.363112862783 213.864537408786 -1.38575154372745 0.16781338510572 NPY1R other 1 1 1 -0.498118902977901 -1.38575154372745 3.98726080562615e-20 526.24142043196 60.968192358625 8.63140926561378 6.83399429010236e-15 35.4157612296278 94.4933066142978 0.374796506742935 0.708324119701571 NAA15 other 5.63718932699425e-16 1 9.52522124154467e-11 8.63140926561378 0.374796506742935 0.00883913418852438 2.56353751027999 28.4487742946388 0.0901106488360408 0.928314879092309 -109.902226554171 45.9980398237555 -2.38928065142056 0.0180756393834024 IL15 other 1 1 1 0.0901106488360408 -2.38928065142056 6.54794504791279e-10 92.4707852906286 13.6248009955856 6.78694575580141 2.40597286866977e-10 65.4770676156585 21.368046623775 3.06425143900641 0.00258241429831041 FAM160A1 other 7.46072858759183e-06 1 3.09720887383859e-06 6.78694575580141 3.06425143900641 4.10268196536797e-12 157.239896033809 41.09125817832 3.82660212913046 0.000189759781325463 -190.931066182549 63.9211226783366 -2.9869792360086 0.0032888229746336 ARFIP1 other 5.11030065606234e-08 1 1 3.82660212913046 -2.9869792360086 1.96447403031824e-11 270.514521443008 36.2991424420139 7.45236672946588 6.75909406362122e-12 30.716012809509 147.367927118498 0.208430785518279 0.835175375201848 ICE1 other 2.3901755526882e-07 1 9.04569558534427e-08 7.45236672946588 0.208430785518279 0.971206301089786 1.47250547595552 6.15208680632593 0.239350568727575 0.811147935838623 1.21132470950025 9.92275051241747 0.122075497916064 0.902996341602209 HHIP other 1 1 1 0.239350568727575 0.122075497916064 1.70929660971775e-14 66.6173486430595 12.3307964190157 5.40251792173998 2.41170569386517e-07 -42.3719238389571 19.8884411643039 -2.13047988471851 0.0346998740546643 ANAPC10 essential 2.27028775702711e-10 1 0.00273993883880022 5.40251792173998 -2.13047988471851 1.22838379108814e-18 552.149963408633 74.4707890620614 7.4143160071594 7.30148045489895e-12 -136.570435195031 120.114537325102 -1.13700171716425 0.257281026713785 ABCE1 essential 1.72096569131448e-14 1 9.76280951624538e-08 7.4143160071594 -1.13700171716425 4.03622381087608e-13 500.411116125956 91.6673839735982 5.45898764025035 1.84832607264502e-07 -223.132042563283 147.851064188609 -1.50916764642721 0.133278647611457 OTUD4 other 5.18493310745141e-09 1 0.00211559402274949 5.45898764025035 -1.50916764642721 8.7379058049925e-08 105.198752581405 29.2020347396708 3.60244597745423 0.000424077784033356 -71.9534616908989 47.1529695250734 -1.52595822523199 0.12905819080285 LSM6 other 0.0008737032014412 1 1 3.60244597745423 -1.52595822523199 1.88228067554188e-19 314.735294117647 37.2774034056963 8.44305840437247 2.13892183581959e-14 -3.06302521008402 59.742466398754 -0.0512704847108204 0.959176428530055 TMEM184C other 2.65119233150074e-15 1 2.96454566444595e-10 8.44305840437247 -0.0512704847108204 4.93836482488512e-23 80.9079768270946 8.49354721748228 9.525817041502 3.36490597428279e-17 -0.0150560224089578 13.6121460425842 -0.00110607264731487 0.999118913379665 PRMT9 other 7.07321993868295e-19 1 4.762014934805e-13 9.525817041502 -0.00110607264731487 0.00258627444416175 20.6403052773224 25.5614867321748 0.807476712664838 0.420705462814039 -85.4802678129563 38.9139957124449 -2.19664586604298 0.0296228769816786 ITGA2 other 1 1 1 0.807476712664838 -2.19664586604298 7.03173210834298e-05 24.7660887322811 48.7943103753011 0.507560995160971 0.612521919509355 -237.415512132619 74.2367350289606 -3.19808666208179 0.0016943945157943 MOCS2 other 0.526184513667305 1 1 0.507560995160971 -3.19808666208179 0.213440235707775 -113.586447410966 68.3625537328099 -1.66153019758317 0.0986413877827065 -160.239649252467 100.282761575392 -1.59787830665194 0.112119883088004 EDIL3 other 1 1 1 -1.66153019758317 -1.59787830665194 2.67926524184545e-12 61.1313465783664 20.8227988537325 2.93578913227645 0.00384074511218329 -96.7904446546832 30.425282259751 -3.18125050832233 0.00177584562850784 TMEM161B other 3.35845898065327e-08 1 1 2.93578913227645 -3.18125050832233 0.00424431457008549 -29.4249685153996 34.5166015301475 -0.852487417966082 0.3952761074903 -143.594327047318 49.2196106530668 -2.91742102674213 0.00406146057473815 ELOVL7 other 1 1 1 -0.852487417966082 -2.91742102674213 1.15233324834618e-07 -10.1913764047395 22.2307641953155 -0.458435720661685 0.647289935474283 -139.705474009587 30.6712171527404 -4.55493739664338 1.06372530658083e-05 NDUFAF2 other 0.00114046421588822 0.154442277262471 1 -0.458435720661685 -4.55493739664338 0.227886377796085 -11.3525133071606 13.3424674253682 -0.850855613525868 0.396162078121045 -33.4928586912016 19.4776881354623 -1.71955000297096 0.0875103970339571 ZNF474 other 1 1 1 -0.850855613525868 -1.71955000297096 0.000117186133403253 60.7038457414264 14.1615687348644 4.28651986781517 3.22105873553089e-05 -15.7117870050903 58.7513422654525 -0.267428562467572 0.789504130689319 LMBRD2 other 0.852529120508669 1 0.311163391614416 4.28651986781517 -0.267428562467572 3.47405989600002e-11 413.264446039084 54.9362281406538 7.52262141079286 5.59625511100122e-12 79.419902207833 229.831186359133 0.345557552332049 0.730186636424865 NIPBL other 4.18797920462803e-07 1 7.50177997629713e-08 7.52262141079286 0.345557552332049 2.4523589480803e-05 97.9865526987088 26.4267364708542 3.70785673088227 0.000291166469708857 17.9771189393581 36.5853855150581 0.491374320272202 0.623861300082948 RNF180 other 0.194496588172249 1 1 3.70785673088227 0.491374320272202 1.97296261719735e-11 113.479508837791 16.5584381815883 6.85327369606465 1.63256917846439e-10 55.0867568220923 24.4784440071587 2.25041905465814 0.0258386077242125 ADGRV1 other 2.39991172755885e-07 1 2.11368731535785e-06 6.85327369606465 2.25041905465814 5.03017488329886e-13 214.12349807167 48.8817469256798 4.38043874326394 2.15606262910395e-05 -191.365389123988 73.908436401488 -2.58922253590166 0.0105233427350225 SLC25A46 other 6.4446600604825e-09 1 0.211876274562046 4.38043874326394 -2.58922253590166 0.0282288638741706 14.7261039539542 26.1040690239363 0.564130593604049 0.573470252758412 -66.0234300819397 39.4689438617852 -1.67279444601164 0.096359279490983 STARD4 other 1 1 1 0.564130593604049 -1.67279444601164 1.41133972919647e-10 82.5435028705425 18.4443931202014 4.47526260867514 1.49405265285186e-05 -49.0140157947225 26.9925691389526 -1.81583366675501 0.0713796883020132 PGGT1B other 1.65931211961629e-06 1 0.149076573701558 4.47526260867514 -1.81583366675501 0.0388748655272532 -9.45315915569316 11.058372436047 -0.854841814232867 0.393975311397766 -36.2437568857877 15.5989942103703 -2.32346755162539 0.0214706057103785 F2RL2 other 1 1 1 -0.854841814232867 -2.32346755162539 1.51217844466106e-11 68.9522495603326 12.2829375866655 5.61366115180687 9.32021693015729e-08 -13.1658340020831 18.0202777933938 -0.730612155541225 0.466155709833269 CCDC112 other 1.84742840584242e-07 1 0.0010845936441624 5.61366115180687 -0.730612155541225 0.00304794628036541 171.106354312739 59.727657803545 2.86477589453681 0.00477214954818068 -292.842704867698 243.058446776816 -1.20482422541191 0.230168618096495 ANKRD33B other 1 1 1 2.86477589453681 -1.20482422541191 0.123212275629496 60.2335203841701 48.299979644749 1.24707134096522 0.214302157022644 -253.606112537983 197.155467376942 -1.28632553746589 0.200298255038368 CMBL other 1 1 1 1.24707134096522 -1.28632553746589 7.52585286784872e-07 11.4629288663359 9.17586422956871 1.24924787241263 0.213469878919966 -51.7724130593475 13.4076949602289 -3.86139550556001 0.00016557753378296 C5orf63 other 0.00693131049128867 1 1 1.24924787241263 -3.86139550556001 2.40923982107299e-07 276.52173553255 63.2220701087986 4.37381653363588 2.23914018698783e-05 -75.0907871132482 92.3795524394786 -0.812850735149892 0.417558489090804 PRRC1 other 0.0023203388716754 1 0.219614869539767 4.37381653363588 -0.812850735149892 0.00324375811207005 -1.81333613136762 77.7364139351155 -0.0233267273286 0.981420047215361 -269.517168564083 109.655365463734 -2.45785664408022 0.015093014702982 F2RL1 other 1 1 1 -0.0233267273286 -2.45785664408022 1.74415941387975e-11 148.976554142834 45.2899749987168 3.28939360525271 0.00125847075410306 -171.812643178477 63.1988317339337 -2.7186047346857 0.00735041407784559 AGGF1 other 2.12613032551942e-07 1 1 3.28939360525271 -2.7186047346857 5.31839229554681e-11 85.4429724988387 33.0678490658257 2.58386846779038 0.0107054458044697 -145.846168068383 46.9612930252704 -3.10566763972836 0.00226295788310353 WDR41 other 6.36717925622865e-07 1 1 2.58386846779038 -3.10566763972836 1.30453216706637e-08 85.8990028202311 65.6922050089238 1.30759810556766 0.192971108015361 -386.579232029444 97.0711540198597 -3.98243160836796 0.000105164034805995 NDUFS4 other 0.000138202137779011 1 1 1.30759810556766 -3.98243160836796 0.676411243873945 -23.6500463262979 38.1807015046361 -0.619424091079787 0.536546441418562 -47.9240623610881 56.89788917073 -0.842281902888968 0.400927926453346 SPINK1 other 1 1 1 -0.619424091079787 -0.842281902888968 0.875652785882752 8.67976913995902 26.5164504470446 0.327335257684402 0.743858862001243 20.2252634340432 39.2349131877866 0.515491479164 0.606948843775165 ESM1 other 1 1 1 0.327335257684402 0.515491479164 0.0148053735431061 71.7355009161805 28.4529703588526 2.52119550301578 0.012693199723541 -11.5099359384099 45.5023162227833 -0.252952748208603 0.800635626605841 GRPEL2 other 1 1 1 2.52119550301578 -0.252952748208603 0.0805254040059894 -130.042527437057 146.432094645419 -0.888073941385258 0.375932332248316 -470.632262750163 218.508177424563 -2.15384279113601 0.0328607056860059 CDC20B other 1 1 1 -0.888073941385258 -2.15384279113601 1.56110998889185e-09 49.6243548523564 17.4393421528863 2.84554052654695 0.00503745582607805 -69.3371971684011 25.2170691596264 -2.74961363390369 0.00668087229160461 ARSK other 1.74438430158775e-05 1 1 2.84554052654695 -2.74961363390369 0.161829374147143 102.75048493645 77.9931402757842 1.31742977104298 0.189626254567953 -18.1978676360882 113.481723884362 -0.160359457128372 0.872805385393399 RHOBTB3 other 1 1 1 1.31742977104298 -0.160359457128372 0.00252546110483725 54.6899128469972 113.589974313861 0.481467780738142 0.630890426435024 -393.530422853455 169.50067074521 -2.32170422171958 0.0216038337983615 GPX8 other 1 1 1 0.481467780738142 -2.32170422171958 8.72580187826431e-05 39.1516224446679 10.2319119691509 3.82642291711554 0.000188143114469445 -5.69465936190154 16.4052073408977 -0.347125107508086 0.728968191166061 TIGD6 other 0.644924016822516 1 1 3.82642291711554 -0.347125107508086 0.00557845539380558 444.091891760785 207.541696904305 2.13977190311569 0.0339383989320086 -80.1043989360415 292.833454686316 -0.273549342310802 0.784795135845757 SERINC5 other 1 1 1 2.13977190311569 -0.273549342310802 0.056713885445466 -7.05430625711539 7.91489658909983 -0.891269541895264 0.374148443701468 15.1056807003195 12.9117224164249 1.16991987692546 0.243806149376333 ENPP6 other 1 1 1 -0.891269541895264 1.16991987692546 2.5694971893339e-07 177.523982588851 46.0852379234095 3.85207911661179 0.000170639937860769 -66.6520080575864 75.5461374887503 -0.882268905773132 0.378988854413393 CASP3 other 0.00246771256278146 1 1 3.85207911661179 -0.882268905773132 1.4754005244926e-12 85.5861894096267 15.0210249419074 5.6977596229701 5.88942168515502e-08 -19.4497570046063 24.6235121400309 -0.789885573349487 0.430793600114885 PRIMPOL other 1.86408380720828e-08 1 0.000692831567041636 5.6977596229701 -0.789885573349487 5.04202897835847e-05 469.86818938695 143.640499333949 3.27114004452572 0.00131685645425166 -53.7649049018546 207.674886195544 -0.258889776644588 0.796059403042519 ERAP1 other 0.383748825542863 1 1 3.27114004452572 -0.258889776644588 0.0139556384722101 -215.978661792898 142.675118113791 -1.51377944976112 0.132092306878626 -600.759584447287 206.279141708709 -2.91236224598816 0.00411010289344104 ERAP2 other 1 1 1 -1.51377944976112 -2.91236224598816 0.00479217293297191 88.5683821323455 38.4983785731398 2.30057434663338 0.0227489687025686 -7.40485206236955 53.8259151550907 -0.137570388557885 0.890758504760198 CMYA5 other 1 1 1 2.30057434663338 -0.137570388557885 0.0450512093862734 18.439528716398 19.4269466453562 0.949172767754826 0.34405949470936 194.366807255836 79.5068030674899 2.4446563030694 0.0156576264760364 EGFLAM other 1 1 1 0.949172767754826 2.4446563030694 7.44050977574395e-19 270.347289267438 40.27930297917 6.71181647327028 3.36276698456171e-10 -135.105564164595 65.4587262398041 -2.06398095296942 0.0406758043857782 CFAP97 other 1.04397792663463e-14 1 4.30535057033436e-06 6.71181647327028 -2.06398095296942 0.148031042207929 -102.469539965737 136.022933945451 -0.753325465004528 0.452492848126998 -353.530689842477 192.626262130522 -1.83531926504875 0.0685360131061093 CARTPT other 1 1 1 -0.753325465004528 -1.83531926504875 3.55451634027407e-07 110.789634864546 20.7608330771484 5.3364734667846 3.43376448830027e-07 -99.893227326266 85.0887051596648 -1.173989275531 0.242259900750449 RICTOR essential 0.00337039239384787 1 0.0038629850493378 5.3364734667846 -1.173989275531 2.713009414772e-13 82.4345065176174 39.2025154510202 2.10278614954215 0.0370897900972153 -240.611355278146 55.1929084385732 -4.35946142512012 2.35700222944913e-05 PAPD4 other 3.50140995070474e-09 0.341034652578994 1 2.10278614954215 -4.35946142512012 0.730834795754518 2.35280816154826 19.1652530651619 0.122764262676246 0.902453839241614 -19.4089044632271 30.6753340266044 -0.632720232040306 0.527854719514609 EBF1 other 1 1 1 0.122764262676246 -0.632720232040306 1.74884244243134e-09 10.8377013841616 24.2624962507966 0.446685339881536 0.65573388233204 -155.352023005358 34.5738457670731 -4.49333938873847 1.37506835026931e-05 ANKRA2 other 1.94943467057822e-05 0.199412412156055 1 0.446685339881536 -4.49333938873847 0.00139216844825724 82.5003224634725 32.2306387548993 2.55968623801884 0.0114524762076006 -60.264615255364 51.7666948294364 -1.16415806444524 0.246183976539454 UBLCP1 other 1 1 1 2.55968623801884 -1.16415806444524 8.60323532528775e-16 63.0005672793284 16.8475451204691 3.73945087125989 0.000260138587208368 -83.0214082491141 24.0076050101308 -3.458129547453 0.000704632941123129 UTP15 essential 1.16874951894034e-11 1 1 3.73945087125989 -3.458129547453 0.0409645103357835 55.0050078231667 34.0933161549341 1.61336631418315 0.108673137675168 -31.3235601885531 57.8777005250184 -0.541202568595707 0.589135073676843 TLR3 other 1 1 1 1.61336631418315 -0.541202568595707 0.0366030046237344 3.96623331971337 2.81217588579111 1.41037882436632 0.160406032042948 -3.94865112663566 4.77402294930294 -0.827111886257732 0.409428992714356 KLKB1 other 1 1 1 1.41037882436632 -0.827111886257732 5.42245181049226e-09 235.840878458735 161.163559701241 1.46336354754094 0.145419297237512 -796.896931737094 229.172874600815 -3.47727423293516 0.000659627838841358 NSA2 essential 5.87251531076312e-05 1 1 1.46336354754094 -3.47727423293516 7.34777121904496e-14 123.700784904465 54.5118818494643 2.26924444190107 0.0246510882932421 -328.951430182262 77.5153185155509 -4.24369578145085 3.79651196658231e-05 GFM2 other 9.62043685709556e-10 0.547153304623842 1 2.26924444190107 -4.24369578145085 0.380118967388869 5.59732988802756 4.01602619812812 1.3937483502066 0.165969379916438 5.22618022230427 13.5350987430805 0.386120583344545 0.700091098681576 TERT other 1 1 1 1.3937483502066 0.386120583344545 5.95457603303254e-10 147.177837153091 21.2990030208911 6.9100810497436 2.49460924575624e-10 42.3917921313964 72.7753172285732 0.582502333837337 0.561321286510877 CCDC127 other 6.80072128732647e-06 1 3.2093147946654e-06 6.9100810497436 0.582502333837337 0.928400157174898 32.7170481185579 132.755434261283 0.24644601782678 0.805708574193907 125.213938804825 331.363535458899 0.377874827510573 0.706112694623923 FOXQ1 other 1 1 1 0.24644601782678 0.377874827510573 0.246140900998346 15.64557214856 15.1427204929119 1.03320748447305 0.30313719959318 -13.3353845059401 23.7068816534635 -0.562511118116283 0.574591088413835 ACSL6 other 1 1 1 1.03320748447305 -0.562511118116283 0.0685396899165973 102.543987621573 83.4006732834515 1.22953429012569 0.220783928155838 -128.852761878171 128.992288806733 -0.998918331244037 0.319432324964134 SEPT8 other 1 1 1 1.22953429012569 -0.998918331244037 0.00300674407449235 36.7632936803211 61.8221307580525 0.594662351969041 0.55297721754422 -244.045676384033 95.733253750947 -2.54922575826082 0.0118141436842096 SHROOM1 other 1 1 1 0.594662351969041 -2.54922575826082 0.0611558117181331 44.2201134675132 37.5844246594006 1.17655422075093 0.241200743144571 -64.1654059165205 57.7178973170959 -1.11170726757426 0.268007873923284 GDF9 other 1 1 1 1.17655422075093 -1.11170726757426 0.0761574175369785 183.171146832365 334.584141863865 0.547459140806778 0.584861042314284 -809.153924084831 513.816383223443 -1.57479198893694 0.117369997922159 UQCRQ essential 1 1 1 0.547459140806778 -1.57479198893694 0.000405326270548132 5.58239902742126 4.64733356109742 1.20120472396284 0.231527998128067 -18.6400108064299 7.13684787537712 -2.61179881257381 0.00990387836534823 LEAP2 other 1 1 1 1.20120472396284 -2.61179881257381 5.51558206837444e-05 20.3568910474634 5.09644183852922 3.99433402605811 0.000100766524202658 5.26602413770493 10.0883033470525 0.521993040508987 0.60243502964027 GJB7 other 0.41775018585868 1 0.921812163405913 3.99433402605811 0.521993040508987 1.97696242847258e-05 48.6181784717321 25.678881597642 1.89331370553913 0.0602292186362398 -127.572768080821 50.8298595076625 -2.50979973811632 0.0131343694611922 SLC35A1 other 0.158216303150661 1 1 1.89331370553913 -2.50979973811632 0.134310252055516 5.44558163245299 5.86586395143861 0.928351164898302 0.354687695928261 -10.2996490402525 11.7952315277485 -0.873204482338682 0.383920040915555 GRIK2 other 1 1 1 0.928351164898302 -0.873204482338682 0.0142908174622709 18.2374711612407 7.15638920995702 2.54841801167913 0.0117999805675343 3.27124455267878 14.2672150910446 0.229284028579068 0.818952394555877 TXLNB other 1 1 1 2.54841801167913 0.229284028579068 0.00361476598003125 283.703270528926 209.467751115416 1.3544007085492 0.177592461277058 -750.784289640825 417.601862073538 -1.79784708313541 0.0741602865837094 CITED2 other 1 1 1 1.3544007085492 -1.79784708313541 6.82761022175872e-07 137.746717134339 30.146007822888 4.56931869531847 1.00149652546379e-05 -63.3309974413735 50.3026446556441 -1.25899936027056 0.20994805352716 CREBRF other 0.00631690497717117 1 0.101701972160848 4.56931869531847 -1.25899936027056 0.000396051497616705 52.3734125072878 26.3182606494386 1.99000280470302 0.0483268922706268 -82.407779664884 54.7654459674709 -1.5047404108392 0.134399938370468 DCBLD1 other 1 1 1 1.99000280470302 -1.5047404108392 0.45500788173209 46.3791788669489 53.609560377799 0.865128878881008 0.388331396528792 -42.6718605852829 86.940036324242 -0.490819447396348 0.624262008243485 SFXN1 other 1 1 1 0.865128878881008 -0.490819447396348 0.365983715527647 -1.28313048619957 1.8516164783999 -0.692978541273521 0.48935339776267 2.34846016851919 4.14047883089159 0.567195308667594 0.571396770283002 SAMD3 other 1 1 1 -0.692978541273521 0.567195308667594 0.312962479137967 -17.388496490944 12.5678070311208 -1.38357443330296 0.168465420742787 -38.1772027509309 28.1034110303741 -1.35845441358236 0.176280716322506 TMEM200A other 1 1 1 -1.38357443330296 -1.35845441358236 0.0150220867422589 75.3650352729065 38.9966976223586 1.93260044742087 0.05529017053634 -55.3068349773057 80.6405728228035 -0.685843776170028 0.493937778621744 DACT2 other 1 1 1 1.93260044742087 -0.685843776170028 1.08166168542639e-09 73.8100911137523 17.7706765969156 4.1534766957924 5.4592732042855e-05 -69.062246570754 36.9521051059273 -1.86896650063046 0.0635643733925605 PDSS2 other 1.218924553307e-05 1 0.514045164915523 4.1534766957924 -1.86896650063046 4.17922649825516e-06 91.2032542703857 29.048612322047 3.139676803121 0.00202336279622513 -95.5789408992783 59.7291034138347 -1.60020719274919 0.111575863274888 STXBP5 other 0.0358619425815276 1 1 3.139676803121 -1.60020719274919 0.290085506349344 1.40056168590235 1.84281271959831 0.760013033884227 0.44843967450367 -4.86845328233315 5.32940557998069 -0.913507746646445 0.362441548161481 PI16 other 1 1 1 0.760013033884227 -0.913507746646445 4.57180908881708e-11 71.124212108946 39.960829438861 1.77984824408523 0.0771254969410983 -321.508293336417 77.5482065689856 -4.1459152643383 5.64124644101077e-05 DAGLB other 5.48571372567161e-07 0.81138047561058 1 1.77984824408523 -4.1459152643383 8.08318595741461e-06 58.2386616165146 17.8540153141267 3.26193635391554 0.00136271453227031 -71.3676960644354 42.9547364455925 -1.66146278547958 0.0986549388664413 KIAA0895 other 0.067397604512923 1 1 3.26193635391554 -1.66146278547958 0.465571553417656 9.39158391665324 34.8458653750967 0.269517884419226 0.787896712514804 -73.535115462431 80.200077808757 -0.916895811968922 0.360649723533119 STK17A other 1 1 1 0.269517884419226 -0.916895811968922 5.45937013119882e-10 190.361931998729 47.9084244384524 3.97345423545051 0.000108821664699958 -292.218223705116 112.888867170693 -2.58854775522966 0.0105672204110635 TRA2A other 6.24770317814393e-06 1 0.990603613763722 3.97345423545051 -2.58854775522966 0.605550855940242 -74.6745319067632 75.4847965997801 -0.989265855781358 0.324105245236771 -67.3275909650573 115.660921550464 -0.582111832263775 0.561353766130476 GALNT10 other 1 1 1 -0.989265855781358 -0.582111832263775 0.00175443075425575 107.937277376929 46.01161104238 2.34587042121849 0.0203004690840649 -101.024248789844 71.1550544231719 -1.41977614392696 0.157761717066027 SAP30L other 1 1 1 2.34587042121849 -1.41977614392696 0.00131792807964238 9346.95051288429 2877.30845996012 3.24850485895205 0.00142432506969137 -1048.8473255402 4623.80656872448 -0.226836332781441 0.820851839983301 RPS14 essential 1 1 1 3.24850485895205 -0.226836332781441 0.00279258130908174 4.13899522591896 4.31790296229633 0.95856605904774 0.339270206929418 23.7583546417961 6.89738496331725 3.44454525420162 0.000735982933205642 MYOZ3 other 1 1 1 0.95856605904774 3.44454525420162 2.62040851885952e-17 355.7672480184 41.5685569107443 8.55856624472919 1.08664859521455e-14 -268.375171112318 134.225060716848 -1.99944160709648 0.0473195004663133 COG5 other 3.62769355350912e-13 1 1.51076754192679e-10 8.55856624472919 -1.99944160709648 0.000388596618850466 47.4629548443666 15.2884222916027 3.1045031291709 0.00227642482155239 -64.7479042950328 46.8445585544044 -1.38218624090215 0.168955660233766 BMT2 other 1 1 1 3.1045031291709 -1.38218624090215 0.294267541230573 -2.47727604851674 1.73070954005292 -1.4313644151063 0.154392259660326 -5.85830244576409 5.30298829030948 -1.10471721321153 0.271039329986582 GPR85 other 1 1 1 -1.4313644151063 -1.10471721321153 1.56875975723183e-08 183.341197239609 44.3250242868176 4.13629095955476 5.7860953147491e-05 -179.291713475632 72.4249936137867 -2.47555028353503 0.0143860846213481 SLU7 other 0.000165315903217091 1 0.542909323382908 4.13629095955476 -2.47555028353503 1.11360885274261e-12 69.420631823159 12.0052439818621 5.78252569694062 4.00973185489614e-08 -64.2208074500491 30.3055093601722 -2.11911328355526 0.0356954320832182 RP9 other 1.41183330350708e-08 1 0.00047527351676084 5.78252569694062 -2.11911328355526 0.173591448852544 203.598700048147 108.415337737813 1.87795107497171 0.0622785096978796 128.965682340984 177.145535047859 0.728021072087092 0.467706177611589 PTTG1 other 1 1 1 1.87795107497171 0.728021072087092 4.80568299384484e-11 267.00211709577 54.8099703783849 4.87141509569335 2.68391189510582e-06 -214.768085002724 89.3930798610836 -2.40251354284328 0.0174501132555417 CAMLG essential 5.76153334132058e-07 1 0.0285299834449748 4.87141509569335 -2.40251354284328 0.878476649238277 -0.647524667401798 4.57822254753357 -0.141435821583343 0.887710505878241 4.1020206504461 11.5608784045951 0.354819115545378 0.723210545378814 BMPER other 1 1 1 -0.141435821583343 0.354819115545378 0.101453639683996 19.636736039175 9.68772910484413 2.02696997682936 0.0445108614452764 5.26588460037936 14.4642674099224 0.364061618272281 0.716345999334728 RELL2 other 1 1 1 2.02696997682936 0.364061618272281 4.40073216306543e-09 125.510919077213 26.2157489681639 4.7876152319597 3.90907911050953e-06 -190.617249463815 87.7173648015031 -2.17308454141509 0.0312924771144452 KCNK5 other 4.79283739879456e-05 1 0.0410648760559026 4.7876152319597 -2.17308454141509 0.0546178718158363 4.92127573633524 4.99877996124181 0.984495371769211 0.326406264162098 -27.114346271291 16.7258164531243 -1.6211074865781 0.107027114113351 KIF6 other 1 1 1 0.984495371769211 -1.6211074865781 3.6491598297328e-17 186.313951101349 34.7694463752868 5.35855386048873 3.14869434580767e-07 -167.194717015992 67.0240713271578 -2.49454731270921 0.013710723709683 ZNF12 other 5.04277396870776e-13 1 0.00355141235263647 5.35855386048873 -2.49454731270921 0.453077154485367 34.4907333671179 45.504913676488 0.757956242095653 0.44965847059089 -21.2967132411495 89.938513296132 -0.236791919953445 0.813139149777248 SLC29A4 other 1 1 1 0.757956242095653 -0.236791919953445 0.755310346378177 -19.8550333908107 29.0720388714069 -0.682959784094763 0.495665089967564 -43.9204479417732 90.0695184117251 -0.487628319949535 0.626511125381077 STEAP1 other 1 1 1 -0.682959784094763 -0.487628319949535 2.42097321661505e-07 388.276830169856 91.934863020947 4.22339053337566 4.1027448358027e-05 -210.271423608947 218.276869896169 -0.963324349066252 0.336894989597102 CDCA7L other 0.00233067091563531 1 0.391155692645429 4.22339053337566 -0.963324349066252 0.530379964044758 -18.2613997022502 31.9589960557123 -0.571400918552514 0.568560895544269 -84.8553324844394 75.4036428784977 -1.1253479174895 0.262192430368172 SP8 other 1 1 1 -0.571400918552514 -1.1253479174895 1.31881967789286e-11 66.2457445162287 21.9354747039127 3.02002785033926 0.00296567994723114 -134.470874115053 41.9404919078146 -3.20623025620731 0.00163961866349688 MIOS essential 1.61410340377308e-07 1 1 3.02002785033926 -3.20623025620731 0.000384661470870884 75.8867612742989 20.1643619373853 3.76340999581061 0.000238350012259856 -14.8733663158106 61.8843906489755 -0.240341161314429 0.810387515994614 KIAA1324L other 1 1 1 3.76340999581061 -0.240341161314429 4.10739920543736e-54 121.746142246025 4.91077060855509 24.7916573488345 2.25531379175257e-54 38.1785849497743 33.6263670271497 1.13537644191385 0.258065423145605 USP49 other 5.99392766049474e-50 1 3.29185601044205e-50 24.7916573488345 1.13537644191385 0.000434815201616337 47.636648333607 12.2159382800044 3.89954887145924 0.000143540373766326 36.2871039238221 25.6776912303263 1.41317627034029 0.159621921406629 SYTL3 other 1 1 1 3.89954887145924 1.41317627034029 0.266150558453601 -2.8052653572921 5.276619348847 -0.53164065319684 0.595740951149098 -26.6506968855239 16.310321334658 -1.6339774268514 0.104306267821109 IQUB other 1 1 1 -0.53164065319684 -1.6339774268514 0.958769589826277 -6.33407079646018 31.027287036947 -0.204145170311462 0.838514941937992 10.0031938252711 98.5340517769482 0.10152017140141 0.919272226529814 HEY1 other 1 1 1 -0.204145170311462 0.10152017140141 7.08562197491876e-05 412.742676128795 99.5267127123081 4.14705424182822 5.58101487004506e-05 22.644491269612 314.809381783281 0.0719308018755323 0.942751537221445 ZNF704 other 0.530004523723923 1 0.524782828230337 4.14705424182822 0.0719308018755323 0.285596498710869 -2.261875018421 16.5602034462996 -0.136584977700043 0.891539589869552 -77.1324587993371 51.7431927643367 -1.49067838064488 0.138118237370863 FABP5 other 1 1 1 -0.136584977700043 -1.49067838064488 0.399441223622755 13.1707140011026 11.3088558991659 1.16463717625706 0.245990500741341 34.8524474137633 32.4149303140888 1.07519735739228 0.283990120089391 SHH og 1 1 1 1.16463717625706 1.07519735739228 0.467494758850735 -3.90218279491599 12.375630778928 -0.315311830533943 0.752951768891227 20.4951578845173 25.8518495636276 0.792792710404483 0.429118267292822 TAGAP other 1 1 1 -0.315311830533943 0.792792710404483 0.116572117283211 -6557.8624424587 4248.60950666418 -1.5435314618047 0.124781276686667 12072.4351475765 13658.8372226991 0.883855261669991 0.378170210025844 COL1A2 other 1 1 1 -1.5435314618047 0.883855261669991 0.272245777053813 25.3380711595155 105.066735955924 0.241161685751282 0.809752688168257 317.528942843106 219.757329796046 1.44490717619203 0.150528900161003 FNDC1 other 1 1 1 0.241161685751282 1.44490717619203 2.77912370297344e-06 132.563532257626 28.1914834625709 4.7022545810201 5.7016930198838e-06 -14.4008534386696 87.7226224236516 -0.164163508121331 0.869819097124956 CHMP4C other 0.024278424669176 1 0.0591436616952546 4.7022545810201 -0.164163508121331 0.000551901981964086 62.1874715497286 16.8996054197897 3.67981796053689 0.000320324915398807 -34.7739184054289 59.2694551292102 -0.586708926708034 0.558241886459117 SLC13A4 other 1 1 1 3.67981796053689 -0.586708926708034 0.182459351841414 36.9945694336694 25.2858414721522 1.46305470887383 0.145530810802561 -16.4108389670841 58.0543234321736 -0.282680737572582 0.777808706794893 PGAM2 other 1 1 1 1.46305470887383 -0.282680737572582 0.000161302985850364 304.68662964332 84.05004006276 3.62506227737442 0.000395067486678511 -320.386307408676 270.925830113627 -1.18256095136556 0.23885428203111 BRI3 other 1 1 1 3.62506227737442 -1.18256095136556 3.55246572080828e-11 276.266303850727 39.0760999033152 7.06995592022449 5.2641720635934e-11 -34.5543080581729 125.219780635352 -0.275949278004226 0.782961842972231 LMTK2 other 4.28107644014606e-07 1 6.91133150229178e-07 7.06995592022449 -0.275949278004226 0.00125618243695478 5667.40614192834 2290.26875593594 2.47455942768267 0.0144538263660476 -841.805425795666 4401.0493399444 -0.191273798763251 0.8485697483456 CTSB other 1 1 1 2.47455942768267 -0.191273798763251 3.21754940965791e-05 131.259693426757 28.836204198241 4.55190608737484 1.08661682649649e-05 138.220429140897 56.1568675955825 2.46132726163255 0.0149683422442564 DLC1 other 0.251194082411993 1 0.109998221346239 4.55190608737484 2.46132726163255 0.0663195530156476 38.7897940074907 18.0885479734427 2.14443934717376 0.0335769033338753 5.25500576202836 43.3491411225485 0.121225141397206 0.903671772324706 ADCY1 other 1 1 1 2.14443934717376 0.121225141397206 0.000535378768898258 8.02775486899698 4.11868962528658 1.94910410818791 0.0531241018542353 -9.2370107213094 8.14850069231701 -1.13358408744062 0.258753807955161 C8orf48 other 1 1 1 1.94910410818791 -1.13358408744062 0.338339577945993 -11.5780773112513 21.0271125557833 -0.550626115713016 0.582687862681355 -74.3132151412347 50.6799666001772 -1.46632328563877 0.144599219816602 C7orf57 other 1 1 1 -0.550626115713016 -1.46632328563877 0.297177354324425 -5.63304156113435 5.08451740427762 -1.10788126251574 0.269663125558278 -24.4924108607498 16.6791050041153 -1.46844874798178 0.144048792744911 HNF4G other 1 1 1 -1.10788126251574 -1.46844874798178 8.96758456063384e-05 231.325789912484 65.3419351178492 3.54023475881561 0.000531809982986664 -210.467477422157 210.236991403979 -1.00109631524233 0.318381796432717 PEX2 other 0.661270706380456 1 1 3.54023475881561 -1.00109631524233 1.31331530615757e-05 97.3610953482619 20.4709235747962 4.75606755076418 4.66680502846522e-06 13.6036201201857 109.900657856786 0.123781061783204 0.901657716662881 MED30 essential 0.107213672466196 1 0.0487867797675754 4.75606755076418 0.123781061783204 0.0318046218542022 195.679898791377 82.1405272548202 2.38225764225167 0.0184601377307585 -212.843402109825 444.483410653819 -0.4788556715688 0.63273860508077 TNFRSF11B other 1 1 1 2.38225764225167 -0.4788556715688 0.849625043079419 -14.1123132559575 69.2454705266908 -0.203801247195192 0.838792611601461 -130.166150396966 228.355961781481 -0.570014241719361 0.569544135075374 SBSPON other 1 1 1 -0.203801247195192 -0.570014241719361 0.116701642187536 55.4928634442439 30.3091761336793 1.83089316580205 0.0691008908517534 -4.81063768154108 77.5731473741863 -0.062014212963878 0.950634068964306 PHKG1 other 1 1 1 1.83089316580205 -0.062014212963878 0.698614545620685 -7.13070461281502 12.5175412735412 -0.569656968328712 0.569751318837762 -28.4190232905948 35.8794233212835 -0.792070235803839 0.429554126613909 EN2 other 1 1 1 -0.569656968328712 -0.792070235803839 2.27557727259189e-07 58.2532180362968 13.9752979160899 4.16829883599327 5.08676706308606e-05 -114.372497790919 43.9612084550526 -2.6016686485736 0.0101761628741549 ORC5 essential 0.00219570451032391 1 0.481004693485418 4.16829883599327 -2.6016686485736 1.07748619990243e-17 548.608985291592 76.6027376160953 7.16174124273493 3.77912405304463e-11 -77.2567217993475 143.805505889658 -0.537230624943014 0.591937490012563 DNAAF5 other 1.49770581786437e-13 1 4.98277506393934e-07 7.16174124273493 -0.537230624943014 1.54512925701632e-06 116.025607563093 22.0297032224888 5.26678032796415 4.77060622554066e-07 42.136783703291 90.6329783323453 0.464916683514229 0.642669825052863 OSGIN2 other 0.0138628996939505 1 0.00532447360832593 5.26678032796415 0.464916683514229 0.856098875644607 -109.236911184142 257.131766168887 -0.424828533680254 0.671582848225904 -19.5816229511574 498.427834787373 -0.0392867765090022 0.968715054645301 DEFB1 other 1 1 1 -0.424828533680254 -0.0392867765090022 5.57538118446329e-14 901.063080180849 201.719090861252 4.46692019249989 1.59317544505606e-05 -958.542539918731 378.685107238378 -2.53123907330039 0.0124398735567334 SUN1 other 7.32660841450321e-10 1 0.158520956783077 4.46692019249989 -2.53123907330039 9.82188773174789e-09 261.352998553698 43.8344494482993 5.96227400693035 1.69174591459664e-08 -105.002866176237 188.000162598274 -0.558525400856231 0.577312942230517 OXR1 other 0.000104750432659091 1 0.000203838465249749 5.96227400693035 -0.558525400856231 0.000391340804616987 29.5680077834373 19.7668584030435 1.49583748618772 0.136884435488037 -66.5789332112403 37.1081133776823 -1.79418804005494 0.0748812301273074 GPR146 other 1 1 1 1.49583748618772 -1.79418804005494 0.473127201064474 -2.72870714817151 15.4982555033615 -0.176065438305599 0.860489893192413 -29.5698620729126 29.0947104819892 -1.01633120189381 0.311176261344415 GPER1 other 1 1 1 -0.176065438305599 -1.01633120189381 1.42696620992091e-07 338.921122129998 81.4367323626839 4.16177211802397 5.371744955274e-05 -46.7359599008297 154.741495205643 -0.302026032763353 0.763062024978631 TMEM184A other 0.00140242239111027 1 0.506448114383232 4.16177211802397 -0.302026032763353 0.217235323467127 -26.8510797492195 29.4224293120316 -0.912605803703618 0.362914332704553 -159.325963002141 93.6693094151228 -1.70094093782673 0.0910262152456962 NOS3 other 1 1 1 -0.912605803703618 -1.70094093782673 0.00155551291037063 127.104864648314 79.4387994987153 1.60003506410453 0.111782510535478 -204.733257025125 149.129614746035 -1.37285446203145 0.171931779067221 MICALL2 other 1 1 1 1.60003506410453 -1.37285446203145 0.0921466667726381 -1.42672113181234 5.33034752107628 -0.267660058968213 0.789328685303542 -36.7596393344625 17.6547673018959 -2.08213672295273 0.0390282554943926 CA3 other 1 1 1 -0.267660058968213 -2.08213672295273 9.68700376961637e-16 1869.05253820179 233.570321373502 8.00209772890193 3.69749946663979e-13 749.200824128656 438.479084053898 1.7086352607792 0.0896730396978525 INTS1 essential 1.31472015161233e-11 1 5.05078427142995e-09 8.00209772890193 1.7086352607792 0.00166268290691417 92.1578023895209 25.4659297135875 3.61886659650794 0.000405471791351549 45.7796135898779 81.7106344991731 0.560265060606538 0.576145742367916 CDK5 other 1 1 1 3.61886659650794 0.560265060606538 2.30394105914232e-05 723.623151546774 164.913886591756 4.38788489254456 2.1633873193867e-05 -296.494468332573 529.146921502234 -0.560325414897687 0.576104688176791 SLC4A2 other 0.183324590075954 1 0.212509536383356 4.38788489254456 -0.560325414897687 7.09703898090383e-05 335.124887225682 81.6601902049957 4.10389550139916 6.68714066284842e-05 -157.544106956856 262.016978371428 -0.60127442097865 0.548577057502799 FASTK other 0.530716574991988 1 0.623174638370844 4.10389550139916 -0.60127442097865 0.000901238432669698 214.470312223043 59.5693021403506 3.60034958471952 0.000432946307276634 -40.1630084304402 191.135588973371 -0.210128363044078 0.833856489080695 TMUB1 other 1 1 1 3.60034958471952 -0.210128363044078 0.000956293301896602 93.7170006700372 32.1320809446192 2.91661784468805 0.00406425596174507 -199.499218289984 115.558041019718 -1.7263984100937 0.0862682452495268 FMC1 other 1 1 1 2.91661784468805 -1.7263984100937 3.04019885593955e-10 120.881689860553 25.6365384572246 4.71521106729162 5.31805842999861e-06 -68.9057953915478 37.6641567693839 -1.82947930610674 0.0692370175419749 PHAX other 3.52237439449156e-06 1 0.0553024896135555 4.71521106729162 -1.82947930610674 8.67134038815481e-08 454.012361404625 98.332751179432 4.61710219595269 8.11757898249969e-06 -97.6016211678199 143.935677189691 -0.678091930183452 0.498724441001952 ALDH7A1 other 0.000867567605834889 1 0.0830509505699543 4.61710219595269 -0.678091930183452 1.72007120491559e-09 520.022976229598 89.8870468894755 5.7852938129007 4.07542495381719e-08 204.999835688466 176.408062055381 1.16207747707193 0.247049654596132 FOXK1 other 1.91787939348088e-05 1 0.000482856348528261 5.7852938129007 1.16207747707193 0.000228408337355549 661.480743151614 189.78887912131 3.48535038625107 0.000643620155593708 -918.12640939207 814.870744424357 -1.12671416377901 0.261650714652875 COX6C other 1 1 1 3.48535038625107 -1.12671416377901 0.0600582388417239 53.6115699670304 23.0268984065153 2.32821498668971 0.021227645117939 127.567709167893 99.0205809681209 1.28829489708773 0.199613891456636 OSR2 other 1 1 1 2.32821498668971 1.28829489708773 1.06797619119567e-10 4365.00375631744 676.246667532594 6.4547508562873 1.3959034567632e-09 -3449.67336624583 2897.23377597841 -1.19067829280737 0.235648324324124 YWHAZ other 1.26341583418448e-06 1 1.7536735127316e-05 6.4547508562873 -1.19067829280737 0.710072142480128 -5.17346211188172 13.9940544413122 -0.369690008966166 0.712124669467485 -48.7622566495969 59.3943537973474 -0.820991450062289 0.412928503171275 BAALC other 1 1 1 -0.369690008966166 -0.820991450062289 6.83333503633563e-05 282.434303493874 68.7915473328132 4.10565417474123 6.54118539078702e-05 -136.33176897647 291.96895850928 -0.466939258449067 0.641207589743193 FZD6 other 0.511953460922265 1 0.610815891791692 4.10565417474123 -0.466939258449067 0.305762268789507 182.024308031374 117.790925443051 1.54531690235661 0.124335523170449 240.430435815994 499.934878002772 0.480923509030831 0.631257878950262 CTHRC1 other 1 1 1 1.54531690235661 0.480923509030831 3.42257507701849e-10 141.095417125818 21.4097037864073 6.59025545301555 6.69061139003757e-10 -34.4935070547308 90.8682702871527 -0.379599027754439 0.704769444704847 SLC25A32 other 3.95752356155648e-06 1 8.48837867054066e-06 6.59025545301555 -0.379599027754439 5.89015473358731e-11 309.20694237376 46.8693150623409 6.59721487208601 6.45072485611153e-10 -219.326667530952 198.925385972058 -1.10255745619998 0.271950669249395 DCAF13 other 7.03755687569012e-07 1 8.18919520483359e-06 6.59721487208601 -1.10255745619998 0.00200520487939725 144.611298741173 46.6505877157329 3.09988160540157 0.00230747642124735 -172.424913373393 194.525785512982 -0.886385899528403 0.376809846995548 TP53INP1 other 1 1 1 3.09988160540157 -0.886385899528403 1.62068640888632e-05 155.024129314022 36.9630248926598 4.19403254371659 4.65396815023045e-05 -187.559450512768 150.147790115822 -1.24916557458546 0.21353747908148 INTS8 essential 0.130951461838015 1 0.441708117138372 4.19403254371659 -1.24916557458546 0.082098093546558 30.898135863691 19.7710167180214 1.56279954158995 0.120165785589039 -25.2787471760782 46.7860440521312 -0.54030529163593 0.589772136837371 FREM1 other 1 1 1 1.56279954158995 -0.54030529163593 0.134805733286161 16.8478281491191 11.275433044194 1.49420674869728 0.137181114271392 77.4200722656754 44.768276911492 1.72935117468865 0.0857631555390673 GEM other 1 1 1 1.49420674869728 1.72935117468865 0.00547725043153913 117.962428120542 40.8983644141543 2.88428228879775 0.00448929387253699 -107.291489039734 162.096281274751 -0.661899756095426 0.509031148228217 PDP1 other 1 1 1 2.88428228879775 -0.661899756095426 0.000244280357919446 94.4199922175625 26.1109077349342 3.61611297378361 0.000405483017326297 -101.212687535129 103.48778258419 -0.978015810250738 0.329610381953382 TMEM67 other 1 1 1 3.61611297378361 -0.978015810250738 3.21101024971671e-29 434.745905483153 30.7101706100471 14.1564145313124 2.27855586138162e-29 758.110527457758 285.246472163024 2.65773848738253 0.0087252215490945 WASHC5 other 4.6495428415898e-25 1 3.30458956576177e-25 14.1564145313124 2.65773848738253 2.69928252422498e-06 69.1426063867131 28.7446475479524 2.40540804236225 0.0174512025207374 -210.286015421047 71.0138777268332 -2.96119606691452 0.00359691512512254 RPP25L other 0.0236106242393959 1 1 2.40540804236225 -2.96119606691452 8.40397004439512e-06 72.1698300867733 17.6334490921492 4.09278013108081 7.07128895338881e-05 -25.5778681709848 43.4495185108136 -0.588680129208315 0.556998134148327 FAM219A other 0.0699798585596782 1 0.657134882438423 4.09278013108081 -0.588680129208315 0.306676494617299 -100.364480329197 112.530280349582 -0.891888654479567 0.373950917939582 -426.121859218155 277.640823720357 -1.534795400432 0.12704364680024 C9orf24 other 1 1 1 -0.891888654479567 -1.534795400432 3.88540789297381e-28 359.087357621983 30.9340046308093 11.6081755953558 8.88745503451693e-23 -25.6785259202694 73.3085018190408 -0.350280326061715 0.726606961870793 SNAPC3 essential 5.62179668034381e-24 1 1.28041564682285e-18 11.6081755953558 -0.350280326061715 0.000309563179275561 23.6323940901718 16.0517732954018 1.47226064405866 0.143088278070364 -110.860773895718 41.0481573295138 -2.70074909832818 0.00773087856071339 NUDT2 other 1 1 1 1.47226064405866 -2.70074909832818 4.32167455872716e-10 131.85910198326 18.9752793160435 6.9489939930304 1.06923354092572e-10 189.281865841995 176.47024132595 1.07259934830815 0.28518505078123 TMEM65 other 4.96992574253623e-06 1 1.39224899363938e-06 6.9489939930304 1.07259934830815 9.46923305331051e-23 1200.0576243865 120.121222096138 9.99038807169346 1.98680578530068e-18 -62.3859069661474 284.667534437806 -0.219153571865349 0.826820611465712 PSIP1 og 1.35457378827607e-18 1 2.8294101188467e-14 9.99038807169346 -0.219153571865349 1.72650100868424e-20 60.3031957618896 6.31533833786647 9.54868805687171 3.07348967073363e-17 4.36346626179896 14.9953898993738 0.290987182799507 0.771455210465612 CCDC171 other 2.44489807839776e-16 1 4.3511393268576e-13 9.54868805687171 0.290987182799507 7.22506792796419e-20 337.256996638402 46.1311790832664 7.31082541874023 1.47420793500359e-11 -468.951512718881 119.334740201261 -3.92971495080126 0.000129441977552683 UBAP1 essential 1.01989058871142e-15 1 1.95922234561977e-07 7.31082541874023 -3.92971495080126 0.0761295595278041 2.80057603625395 29.2912569368922 0.0956113301074027 0.923952766996073 -83.1020589439864 44.3976220406455 -1.87176824172942 0.0631229227060796 DIRAS2 other 1 1 1 0.0956113301074027 -1.87176824172942 1.22030410452699e-06 386.408041636305 162.60355044693 2.3763813309994 0.0187044677560705 -701.676850576301 246.462997158626 -2.84698660109492 0.00501178106529689 SYK other 0.0110486333623874 1 1 2.3763813309994 -2.84698660109492 1.04955637513435e-13 25.6312199278268 3.83285319842579 6.68724279300701 3.71722814767642e-10 -6.59040697674418 5.81992855911427 -1.13238623288997 0.259187662042545 NIPSNAP3B other 1.36830664626265e-09 1 4.75136101836e-06 6.68724279300701 -1.13238623288997 0.00849382031196726 248.773797113071 104.801206993903 2.37376843500995 0.0188090259318462 -87.5662790697675 159.133550396339 -0.550269122078117 0.582911896286476 ABCA1 other 1 1 1 2.37376843500995 -0.550269122078117 0.0513599721774143 54.7968953613922 40.7844276609436 1.34357396938213 0.181049837265567 -62.272651841135 61.8181598808077 -1.00735207843785 0.315335596409438 NFIL3 other 1 1 1 1.34357396938213 -1.00735207843785 2.51036234604242e-05 24.2972705397043 5.8893899772413 4.12560055177152 6.38277231237776e-05 -21.5098439326229 20.6591114206268 -1.04117953065235 0.299626153795272 LETM2 other 0.198921112300401 1 0.596789211207321 4.12560055177152 -1.04117953065235 4.30987874247464e-10 135.028291069046 22.1209356366027 6.1040949301267 7.86940482855644e-09 -166.029458636974 77.8597069771485 -2.13241823123869 0.0345376863660934 METTL2B other 4.95722252959434e-06 1 9.61956046242739e-05 6.1040949301267 -2.13241823123869 2.06794544059598e-15 163.300320441671 18.1660032957313 8.98933671778229 8.4747566529431e-16 39.7424299679897 33.2018857876078 1.19699315340766 0.233148593789345 FXN essential 2.79296711206893e-11 1 1.18917785354098e-11 8.98933671778229 1.19699315340766 0.84209111619632 -1.38592857142858 3.11437217029426 -0.445010581794929 0.656949361831353 -9.0279285714286 19.6401185681218 -0.45966772247913 0.646415864731465 TMEM71 other 1 1 1 -0.445010581794929 -0.45966772247913 0.56212537568882 -7.37964256174208 11.0161690891175 -0.669891910885079 0.503929910047188 -20.5897075316089 20.3621863352257 -1.01117371153753 0.313519390463707 MAMDC2 other 1 1 1 -0.669891910885079 -1.01117371153753 0.281620737233704 5.05098300566473 5.87841455927204 0.85924239516211 0.391577875950548 -18.9130877942647 20.22718408059 -0.935033157305061 0.351274047747768 C8orf34 other 1 1 1 0.85924239516211 -0.935033157305061 0.177691020756627 0.543803989319933 4.22642270641533 0.128667676447623 0.897787413478273 -13.2883712894613 7.77513648983916 -1.70908527545812 0.0894365753804233 TMC1 other 1 1 1 0.128667676447623 -1.70908527545812 0.553633110981049 100.470017276582 117.241736753095 0.856947534717667 0.392796858734132 -73.3546788126278 215.683704371885 -0.340103018103531 0.734239407718433 ALDH1A1 other 1 1 1 0.856947534717667 -0.340103018103531 7.05971748211406e-17 307.810594781799 34.7297960847173 8.8630118654008 1.7978960881068e-15 -3.8780660352455 101.57333758346 -0.0381799606816997 0.969593647023783 KDM1B other 9.73040860559781e-13 1 2.51615557530547e-11 8.8630118654008 -0.0381799606816997 0.000375120971887758 507.24758028458 132.30548721384 3.833911888059 0.00021739139760748 212.740248809868 293.378827135563 0.72513838468502 0.470011364824084 HGSNAT other 1 1 1 3.833911888059 0.72513838468502 0.000185066994572872 54.7061084945815 53.1822948579524 1.02865264917016 0.305255844072318 -214.838946263405 71.7016893132055 -2.99628848805711 0.00318620276278383 RASEF other 1 1 1 1.02865264917016 -2.99628848805711 3.92856565205782e-06 32.9906042820652 14.077195597228 2.34354947007779 0.0203876667993615 -52.0235736015843 19.0159011462608 -2.73579322912151 0.00695904014154043 GKAP1 other 0.0338131645672616 1 1 2.34354947007779 -2.73579322912151 9.09890346800378e-06 42.2558362369338 12.9633421973157 3.25964057677069 0.00137666421570784 -26.9656794425087 17.5456856640828 -1.53688376497645 0.126400804445112 KIF27 other 0.0754845031705594 1 1 3.25964057677069 -1.53688376497645 3.69574215186102e-08 45.8651567944252 25.0186000852454 1.83324233323006 0.0687228099870418 -138.380023228804 33.862293085344 -4.08655205009422 7.06620312713238e-05 C9orf64 other 0.000379552718996127 1 1 1.83324233323006 -4.08655205009422 0.584024078903869 46.5075097175435 45.0141842619787 1.03317455331132 0.303101048128933 40.8912796061157 72.8025314568563 0.561673870232773 0.57513409234463 SVEP1 other 1 1 1 1.03317455331132 0.561673870232773 0.00397133789669503 26.9805424664718 8.17079995671876 3.30206866027677 0.00120145371627567 -2.67402911560638 32.9667302471038 -0.0811129613268606 0.935460969457044 TRPV6 other 1 1 1 3.30206866027677 -0.0811129613268606 2.99998874882587e-06 167.517914679727 55.623565292516 3.01163569431005 0.00303218706749278 -173.567308931564 83.1220611527283 -2.08810160052036 0.0384135014443524 ANKS6 other 0.0260939021372874 1 1 3.01163569431005 -2.08810160052036 0.0681896496974841 -17.1463633738651 47.7299993779749 -0.359236614232544 0.719910169303444 -158.358507919193 73.7259170287403 -2.14793541133521 0.0332828823543415 FBP1 other 1 1 1 -0.359236614232544 -2.14793541133521 0.0025577908440115 96.5161107703929 72.2468522215119 1.33592132809427 0.183508229193004 -225.187149124876 108.410664099806 -2.07716787822241 0.0394147658040591 TMEM246 other 1 1 1 1.33592132809427 -2.07716787822241 0.000187737623886751 127.661457696739 30.8991445103931 4.13155314555066 5.9670370909085e-05 11.3841186194458 179.099584501736 0.0635630654929605 0.949402767237966 ZHX1 other 1 1 0.559171045789036 4.13155314555066 0.0635630654929605 0.00113881666619408 85.1068730086482 28.1206273738648 3.02649268372106 0.00292192107152032 309.834898828981 112.565240891064 2.75249176723058 0.00665997537260643 METTL27 other 1 1 1 3.02649268372106 2.75249176723058 0.628980060509874 -6.04977817213842 7.049403477109 -0.858197178212797 0.39219996206279 7.83709768492379 28.8467836116815 0.271680121791816 0.786254416976787 NCF1C other 1 1 1 -0.858197178212797 0.271680121791816 7.88860310860752e-08 162.706276150628 29.3781365953436 5.53834568855591 1.24788482464178e-07 27.532719665272 46.1207755080919 0.596970006725958 0.551381881237233 KIAA1958 other 0.000791384663855507 1 0.00144255485728589 5.53834568855591 0.596970006725958 0.100567502752388 0.126164956726102 53.9288537208819 0.00233947039518195 0.998136325571128 -159.855282856652 84.6629788038956 -1.88813676432202 0.0608407297516491 RNF183 other 1 1 1 0.00233947039518195 -1.88813676432202 3.38482614578834e-09 291.957094856552 55.3681666073464 5.27301358788019 4.41010971302873e-07 -60.5069271324035 79.6557156041967 -0.759605593565413 0.448636725499194 STRBP other 3.71552366023186e-05 1 0.00493226670305133 5.27301358788019 -0.759605593565413 0.0670307962463801 1745.28224471021 744.077669520098 2.34556460461426 0.0203438995756589 1061.24734465167 2975.20759174512 0.356696906661627 0.721833709707729 CLDN3 other 1 1 1 2.34556460461426 0.356696906661627 1.94225366428245e-11 308.886610007805 52.7116710571594 5.85992824383912 2.63749870939209e-08 -77.6432659786666 76.335285084348 -1.01713468277315 0.310654228711946 GAPVD1 other 2.36352848406531e-07 1 0.000315233845746543 5.85992824383912 -1.01713468277315 2.60655775753041e-09 45.7454764172219 39.5576602506539 1.15642523160772 0.249286515729262 -289.315272417423 58.5343530600568 -4.94265772649068 1.98085601525062e-06 CARD19 other 2.87868238741658e-05 0.0288788998463388 1 1.15642523160772 -4.94265772649068 0.0182790622483458 441.53202846975 165.13718083968 2.67372875220876 0.00832145928031578 142.511454626333 251.197136396392 0.56732913707045 0.571327520918609 WNK2 other 1 1 1 2.67372875220876 0.56732913707045 1.89671085232674e-06 67.7155774763666 21.3567333129246 3.17068984681224 0.00183532928233306 -65.3637776275142 32.8932257478235 -1.98715012412059 0.0486793233409749 ZNF367 other 0.0168673335939553 1 1 3.17068984681224 -1.98715012412059 3.60205082436026e-05 65.9038276542961 53.6227434974733 1.22902752369247 0.220973319262547 -449.609766594097 131.477373428935 -3.41967408435579 0.000806400798241713 NDUFB6 essential 0.279230979904408 1 1 1.22902752369247 -3.41967408435579 0.0134427811001466 12.5927595328361 4.80731918403467 2.61949728128253 0.00971693699674255 -0.738884326327173 12.2252947652328 -0.0604389784063503 0.951887005366328 AQP7 other 1 1 1 2.61949728128253 -0.0604389784063503 8.48233787761362e-19 391.414842653947 45.2909188279609 8.64223673935054 7.67518010859127e-15 -175.442653707565 115.267998586418 -1.52204129384647 0.130104061800851 NOL6 essential 1.18947824057776e-14 1 1.06907583732568e-10 8.64223673935054 -1.52204129384647 0.122561360519 76.5537591795029 55.9794242236543 1.36753387947772 0.173517272254285 -106.348424802086 142.358960518993 -0.747044122929637 0.456214157059535 AQP3 other 1 1 1 1.36753387947772 -0.747044122929637 2.17360003697128e-13 58.8261372397842 7.90655895391147 7.44016930534391 7.40114072083938e-12 0.0497158685285127 17.43836005536 0.0028509486196342 0.997729088638514 TRMT10B other 2.81133428781865e-09 1 9.89384491561808e-08 7.44016930534391 0.0028509486196342 1.53318440383567e-17 1388.42196852481 185.612451003198 7.48022000151748 7.43255371022303e-12 -1140.78268186385 475.382979847387 -2.39971292668088 0.0177233773942096 VCP essential 2.12805995252391e-13 1 9.93509454445512e-08 7.48022000151748 -2.39971292668088 2.64713227031354e-17 326.045486768213 46.1227680911775 7.06907890098167 6.77026214133716e-11 -337.053765495645 118.127737743284 -2.85329908059471 0.00498378250406441 PIGO other 3.66442520179503e-13 1 8.86565827408101e-07 7.06907890098167 -2.85329908059471 1.36994310805976e-08 329.303083805222 114.077297681082 2.88666623858702 0.00450691341038403 -1055.49563180957 292.108236140662 -3.61337169316003 0.00041956623024971 STOML2 other 0.000144898882539481 1 1 2.88666623858702 -3.61337169316003 0.00303611370687838 69.4947904607547 23.5248429175969 2.95410221033917 0.00366393239856496 -12.4454220369942 44.092905825567 -0.282254521537517 0.778153625562638 SLITRK5 other 1 1 1 2.95410221033917 -0.282254521537517 3.76408358135331e-07 134.040714861367 40.1435049288045 3.33903865890863 0.00106703468193187 -233.77076081382 93.7327425111139 -2.49401387979341 0.0137457956217968 MELK other 0.00356195229303464 1 1 3.33903865890863 -2.49401387979341 0.626135759719548 23.6151396959325 26.7341551467237 0.883332185600282 0.378442670211849 -6.91105750096432 109.641967645156 -0.0630329576292463 0.949822533011557 ARMC3 other 1 1 1 0.883332185600282 -0.0630329576292463 1.50232929446401e-07 275.128452654051 47.9421355244842 5.73876089673857 5.05781787510464e-08 161.709068728204 206.053144759966 0.784793015008726 0.433804451522336 OTUD1 other 0.00147363480493975 1 0.000596873087441098 5.73876089673857 0.784793015008726 6.54081414201277e-11 118.210013808866 17.1509521356116 6.89232952632519 1.30133231091405e-10 -24.3946835864959 75.3721132755998 -0.323656622142147 0.746634298175876 ARHGAP12 other 7.80384535283543e-07 1 1.6896498724908e-06 6.89232952632519 -0.323656622142147 0.320441396089188 15.4870833333333 10.8903192694529 1.42209635458294 0.157007455031331 31.7174868421053 30.333979510994 1.045609160203 0.297369392191145 FAT3 other 1 1 1 1.42209635458294 1.045609160203 0.665498090758976 1.36820393718203 7.22448892438083 0.189384183643037 0.850039487841352 -14.7218690555187 20.0073657023976 -0.73582246031293 0.462950794373746 DEUP1 other 1 1 1 0.189384183643037 -0.73582246031293 0.000605271536566115 20.4872625915603 19.5338219751668 1.04880973204351 0.295867349176396 -83.4180333182085 33.8737545308549 -2.46261551084409 0.0148663225445941 HECTD2 other 1 1 1 1.04880973204351 -2.46261551084409 7.5845458841886e-13 179.500874737579 28.6209097259108 6.27166908587377 3.93175371997568e-09 -90.8089573128061 42.7785776630262 -2.12276710151803 0.0354839862891283 FBXO33 other 9.66195300186786e-09 1 4.86279300086592e-05 6.27166908587377 -2.12276710151803 1.08317756792162e-06 147.005678480517 78.1751822270069 1.88046480088321 0.0619964599808149 -485.301169263476 128.688351807162 -3.77113516840043 0.000233790807135423 SPTSSA essential 0.009853666335383 1 1 1.88046480088321 -3.77113516840043 1.2998211816102e-15 93.6857142857142 18.2288069180459 5.13943203781309 8.35045657666978e-07 -63.72 34.5546897436764 -1.84403334171625 0.0671251852357763 WRN ts 1.76151766531815e-11 1 0.00916462609289508 5.13943203781309 -1.84403334171625 3.02753812211243e-05 178.835017952975 42.7880843629699 4.17955186859788 4.89619117935584e-05 -29.064414501371 97.4005564251118 -0.298400908250639 0.765802065912863 MARCH8 other 0.237177336486288 1 0.463718266596791 4.17955186859788 -0.298400908250639 0.418581440400768 -7.52409069000034 26.0923638391627 -0.288363704276852 0.773451133952906 42.4401486782099 40.3478265784985 1.05185712037402 0.294491712742991 TSHR other 1 1 1 -0.288363704276852 1.05185712037402 0.000371700989691287 42.7710432118614 69.5108420389286 0.615314704257331 0.539291909412556 -381.393599315903 114.550952358464 -3.32946685700533 0.001098335128563 CFL2 other 1 1 1 0.615314704257331 -3.32946685700533 1.04234368346338e-16 254.934739466721 43.7366159181355 5.82886293589559 3.63649357885155e-08 -283.334825971911 76.5896501491197 -3.6993879123388 0.000308921757168427 SUGT1 essential 1.43332679913049e-12 1 0.000432015437167565 5.82886293589559 -3.6993879123388 2.39929452746556e-06 236.563957584072 52.5041094931919 4.50562746168939 1.29097895987695e-05 -53.212784101442 81.1895279993835 -0.655414379325448 0.513166360560682 GTF2A1 essential 0.0211113925471695 1 0.129716348717138 4.50562746168939 -0.655414379325448 0.661888819004105 56.3878793278802 64.2787325201182 0.877240062414604 0.381731629082236 25.9324924590792 156.192242834527 0.166029323790123 0.868353069308899 ZCCHC24 other 1 1 1 0.877240062414604 0.166029323790123 0.164283633055388 70.786780583252 67.2762337750736 1.05218108403504 0.29436464935877 -307.248389603032 258.356661353196 -1.18924121404014 0.236175176117813 PGM2L1 other 1 1 1 1.05218108403504 -1.18924121404014 0.457111045190727 26.6491606675123 35.5574026552651 0.749468709114675 0.454710720806111 -55.5710261436833 81.7193194563343 -0.68002311464888 0.497504226527637 PHYHIPL other 1 1 1 0.749468709114675 -0.68002311464888 0.000591984619462351 235.887222946545 68.2361796416931 3.45692306024729 0.000704217344884761 -88.2870491090831 155.190927867028 -0.568893106849195 0.570246801715431 SLC16A9 other 1 1 1 3.45692306024729 -0.568893106849195 0.466088214054654 -25.5778949371639 27.4475322867243 -0.931883226148357 0.352924864643213 49.3919380872165 98.5307330975993 0.501284589431517 0.616920704378191 FOLR2 other 1 1 1 -0.931883226148357 0.501284589431517 0.000172309569303264 912.788540839587 276.242844549736 3.30429750072764 0.00120152389843899 -1604.18737948269 985.209804833116 -1.62826980772327 0.105653617051955 INPPL1 other 1 1 1 3.30429750072764 -1.62826980772327 0.202899400386253 -74.4838571794941 76.8374460844295 -0.969369246052904 0.333953231618404 -475.07002464879 274.325001472438 -1.731778081104 0.0854108741494216 PHOX2A other 1 1 1 -0.969369246052904 -1.731778081104 0.215607468499485 -170.314917898524 120.960345546801 -1.4080227460381 0.161221393946019 13.5352720828133 199.951211667595 0.0676928735261416 0.946121487563027 GJB2 other 1 1 1 -1.4080227460381 0.0676928735261416 0.00139788193357083 -99.8186383104419 57.2290246396335 -1.74419604281205 0.0832010457762744 -347.278983901935 94.2367546549442 -3.68517554720052 0.000319987431848941 CRYL1 other 1 1 1 -1.74419604281205 -3.68517554720052 0.0436359745701937 -47.6043331622546 70.8813254415057 -0.671606136958313 0.502853911076012 -395.176809150231 157.058319317292 -2.51611510213532 0.0129038460707853 REEP3 other 1 1 1 -0.671606136958313 -2.51611510213532 4.75904017004505e-07 131.220139465745 29.4089306171811 4.46191468754341 1.59167629872116e-05 -18.3832138329035 47.5249550275587 -0.386811809127299 0.699447413815044 SKA3 essential 0.00446302787146825 1 0.158387708485743 4.46191468754341 -0.386811809127299 3.2402658137735e-22 224.290550400463 33.0742972095441 6.78141545924492 2.65378613886413e-10 -226.79549631841 53.7030234129913 -4.22314204871277 4.19009541122746e-05 MICU2 other 4.62418334283616e-18 0.603583243987315 3.41011518844041e-06 6.78141545924492 -4.22314204871277 9.59839777629146e-05 62.0287562904387 16.0364550258338 3.86798430142534 0.000161175991663507 -48.1437814521925 57.2734569936356 -0.840594997741141 0.401869699758731 DDIAS other 0.705578220535185 1 1 3.86798430142534 -0.840594997741141 0.000213986020060076 124.659353717593 36.5005829799294 3.41527021050978 0.000814790621911064 -152.853826201398 127.622711197549 -1.19770082273831 0.232873688899898 PCF11 essential 1 1 1 3.41527021050978 -1.19770082273831 0.139765801013892 61.3793964177497 32.832225981132 1.86948629230998 0.0634662491259047 -12.0430894520703 91.8939134334137 -0.131054266839955 0.895904543463645 PKNOX2 other 1 1 1 1.86948629230998 -0.131054266839955 0.00143184290837556 31.7448551106105 17.6796148608885 1.79556259343849 0.0746466217245678 -61.1574868699729 28.3379832522135 -2.15814535302881 0.032562928971736 LRR1 essential 1 1 1 1.79556259343849 -2.15814535302881 3.10322965986106e-05 -98.3836293965699 193.315176499113 -0.508928637566234 0.611575789214503 -1382.91643916115 309.857554994005 -4.46307155295246 1.61140251359184e-05 RPL36AL essential 0.242796688587529 0.233476110194322 1 -0.508928637566234 -4.46307155295246 2.37096146959877e-10 162.60968622602 32.9709218855474 4.93191202813467 2.20220860240635e-06 -139.066023529988 52.8478385730926 -2.63144202837452 0.00942199050612044 DNAAF2 other 2.76003624675993e-06 1 0.0235504187941335 4.93191202813467 -2.63144202837452 0.463237292452166 -159.018979392283 127.955251236475 -1.24277024862699 0.215891705807734 -158.799004185367 286.785695868751 -0.553720099966362 0.580594880255163 C10orf10 other 1 1 1 -1.24277024862699 -0.553720099966362 0.0103867034438262 125.534510973031 52.030561673971 2.41270720388613 0.0170333722895201 -87.2346584142776 116.602299355244 -0.748138406331988 0.45554030536927 ZNF22 other 1 1 1 2.41270720388613 -0.748138406331988 1.85434099456434e-13 562.004059949033 77.9634495479549 7.20855815395068 2.57913081597143e-11 -118.453185332354 124.652541146863 -0.950266911869811 0.343505232015546 KLHDC2 other 2.40248419255756e-09 1 3.4121900695302e-07 7.20855815395068 -0.950266911869811 1.66816660741916e-06 84.352282946146 19.3506226664018 4.35915083459333 2.37686253505369e-05 -33.8502660894913 33.5596892660364 -1.00865850756696 0.314720630858173 EML5 other 0.0149167458035422 1 0.232457155928251 4.35915083459333 -1.00865850756696 9.9018365515134e-12 451.670355122404 66.4335743155585 6.79882664414498 2.29741617818801e-10 -49.3279120207038 106.598161840236 -0.462746366064305 0.644212343041961 NEMF other 1.21772785910512e-07 1 2.96022074559525e-06 6.79882664414498 -0.462746366064305 9.16057522058394e-14 116.172965510998 15.3129590496314 7.58657847477199 2.98270231835983e-12 -63.1361059563683 42.5712121939209 -1.48307042958443 0.140112654293003 RPUSD4 essential 1.19664594106488e-09 1 4.01889310375804e-08 7.58657847477199 -1.48307042958443 0.000279040324702407 538.086139088731 202.3746489474 2.65886138351542 0.00867464331975821 -576.879397815079 330.715391369714 -1.74433791976187 0.0831083819394704 ARF6 other 1 1 1 2.65886138351542 -1.74433791976187 1.51394770069995e-08 97.0348023346866 25.9514830125399 3.73908505682696 0.000260485438053236 -138.067693406851 45.0815324337609 -3.06262200846247 0.00259293962562256 TTC8 other 0.000159660924515817 1 1 3.73908505682696 -3.06262200846247 0.0687943339008425 58.0994612515541 24.9591410459439 2.32778288101368 0.0212337215601615 35.6358267716536 40.1055753111227 0.888550444550548 0.375639539250828 TMEM63C other 1 1 1 2.32778288101368 0.888550444550548 0.358015788905937 18.7450025530949 43.4936634808261 0.430982378878213 0.667079944755454 98.4144240406984 69.1824387065919 1.42253476287648 0.156880438662041 NGB other 1 1 1 0.430982378878213 1.42253476287648 0.00381384924493319 3.95361557140618 1.56623297405724 2.52428319215152 0.0125996686603566 -2.41406454188189 2.47408950005926 -0.975738566379295 0.330714399734582 NOXRED1 other 1 1 1 2.52428319215152 -0.975738566379295 1.16345797641974e-05 17.1434404260329 3.46619105559398 4.94590175529005 1.97462622757134e-06 30.8297396409981 15.3195541904122 2.01244365585345 0.0459277387591019 AKR1E2 other 0.0954966307045326 1 0.0211897140480681 4.94590175529005 2.01244365585345 3.0103811618842e-15 128.776927109499 19.1490454340364 6.72497893187958 3.23595105097046e-10 -42.5887540682817 33.3691504634294 -1.27629122937836 0.203774003535402 KBTBD6 other 4.05197304389613e-11 1 4.14622408160844e-06 6.72497893187958 -1.27629122937836 2.13035385146355e-21 439.875218120602 42.732814813578 10.293616744873 2.91237622601023e-19 -275.690020152776 216.757943042516 -1.27187966578323 0.205320855457879 NUDT5 other 3.0331978137138e-17 1 4.16091191410082e-15 10.293616744873 -1.27187966578323 0.782292211668982 -5.83072716807363 24.3351453786545 -0.239601082193987 0.810952049043758 -23.6289556152468 34.1293486974771 -0.69233538045786 0.489749451183751 DACT1 other 1 1 1 -0.239601082193987 -0.69233538045786 0.39262915900009 -29.6236125106691 26.3635047466507 -1.12365987737016 0.26292887218252 -57.8735657873693 48.7180293980226 -1.18792911992697 0.23671424152849 OXGR1 other 1 1 1 -1.12365987737016 -1.18792911992697 8.77918719983522e-06 169.719799668072 35.0423301760707 4.84327950839205 3.06763059200145e-06 50.5018481256822 174.888267136045 0.2887663589599 0.773146006740707 BEND7 other 0.0729550456306307 1 0.0324800727081113 4.84327950839205 0.2887663589599 4.37809631934326e-07 563.094400373234 202.07993607377 2.78649336155607 0.00599870695067718 -2524.09874207948 738.692407422216 -3.41698211152288 0.000810046163690358 ATP5C1 essential 0.00412285330392555 1 1 2.78649336155607 -3.41698211152288 4.8920037128679e-15 70.2592088063801 8.39645993866389 8.36771798110434 3.21673689304935e-14 -28.7569971751827 41.9048140169887 -0.686245670092327 0.493583461884766 PRPF18 other 6.56360138155486e-11 1 4.44617373357281e-10 8.36771798110434 -0.686245670092327 2.53974491972485e-06 71.5147333960683 14.1123681299446 5.06752181756959 1.14087376788457e-06 32.0355572411758 51.587007551961 0.621000495307039 0.535517349313585 TAF3 other 0.0222786424358264 1 0.0124263970797987 5.06752181756959 0.621000495307039 0.714992866992763 -30.8495467851988 38.3833172746529 -0.803722788326345 0.42276462143009 -38.5913312234017 81.3487726783694 -0.474393527435026 0.635874288327517 VSTM4 other 1 1 1 -0.803722788326345 -0.474393527435026 0.000511886910816674 189.461337456177 177.907857542198 1.0649408074134 0.288648812194003 -1289.22362069841 409.546534520784 -3.14792950746599 0.00199149255352374 VDAC2 other 1 1 1 1.0649408074134 -3.14792950746599 0.196287371905301 -44.8782091762298 71.3875471347766 -0.628655990820103 0.530549902537055 -297.961910879805 164.335195425824 -1.81313509931776 0.0718510457262073 COMTD1 other 1 1 1 -0.628655990820103 -1.81313509931776 0.0356099106165394 -0.849859043713838 11.8334278924325 -0.0718185002215057 0.942838342613905 -48.8509165044689 21.2156543171755 -2.3025882574322 0.0226237070067559 SLC18A2 other 1 1 1 -0.0718185002215057 -2.3025882574322 0.000653757134081372 149.949518947711 52.1341777331228 2.87622295905979 0.00458798489033086 -83.2835634118582 93.469170805819 -0.891027091541004 0.374286818310063 PDZD8 other 1 1 1 2.87622295905979 -0.891027091541004 2.81993428984683e-05 848.489000197718 229.995699032953 3.68915159616158 0.000314104858343054 -660.108501944242 516.741005714263 -1.27744555714484 0.203418638755455 ZNF503 other 0.222041625982539 1 1 3.68915159616158 -1.27744555714484 0.00222927941668986 172.963817966492 49.8925273462209 3.46672792833761 0.000716188849553134 76.2668675328296 74.0794274932162 1.02952830648986 0.305157949687584 QSOX2 other 1 1 1 3.46672792833761 1.02952830648986 5.74453343193202e-06 110.540382148909 34.2312297244565 3.22922614929996 0.00151355693050495 -115.810723012255 61.3494509458854 -1.88772224081366 0.0609203214378096 FAM204A other 0.0485470520332575 1 1 3.22922614929996 -1.88772224081366 0.00195182834345972 507.422046708233 149.1176410723 3.40283043011797 0.0008539732047382 105.429633321672 246.641693591311 0.427460709446676 0.669652749497229 NSD1 other 1 1 1 3.40283043011797 0.427460709446676 6.32626032603311e-05 695.926738383161 223.324682728498 3.11621057681841 0.00218346675203358 -544.08238558347 400.709132323116 -1.35779881638621 0.176500907850224 PRDX3 other 0.475544988707909 1 1 3.11621057681841 -1.35779881638621 0.000194184803481733 307.238003777669 170.963916688535 1.7970926832321 0.074255379018346 -808.926335448546 343.175404385586 -2.35718039553805 0.0196556935978104 GHITM other 1 1 1 1.7970926832321 -2.35718039553805 1.00191404638702e-07 338.82648773214 60.588107210917 5.59229365843416 1.31106048656332e-07 83.6934797343093 90.6221254885116 0.923543552781924 0.357475361106621 SNAPC4 essential 0.000997004667559723 1 0.00151388154383467 5.59229365843416 0.923543552781924 0.36840726493455 -2.25650377847155 1.5923974987108 -1.41704805508575 0.158475733637909 -2.78125813506729 6.96142445905609 -0.399524285787396 0.690056909610017 TMEM52B other 1 1 1 -1.41704805508575 -0.399524285787396 2.95819985606568e-06 325.841534499119 81.8483089507734 3.98104174265948 0.000114756523376833 -113.5733767114 122.42118241025 -0.927726513298988 0.355309244592222 PMPCA essential 0.0257422551474835 1 1 3.98104174265948 -0.927726513298988 0.00224231873073809 101.680628981971 43.9102342234681 2.31564761108988 0.0221808256252756 -73.8296055307036 65.6768950080696 -1.12413361687748 0.263076629874854 SDCCAG3 other 1 1 1 2.31564761108988 -1.12413361687748 0.010234366326618 -6.69594848010826 20.4608847384942 -0.327256057872747 0.743907400624332 -75.4712868690749 28.256020786674 -2.67098072438665 0.00835479513835628 AK8 other 1 1 1 -0.327256057872747 -2.67098072438665 0.00328155338480579 1.78124170988971 45.3738844809841 0.0392569807558843 0.968735064075541 -173.798854097106 62.6603120760841 -2.77366722792689 0.00621059979852647 SPACA9 other 1 1 1 0.0392569807558843 -2.77366722792689 3.55203665490763e-10 365.773072806609 56.9513127058326 6.4225573639701 1.49844950603396e-09 104.831444331623 78.6484795848963 1.33291126395474 0.184479777524984 TSC1 ts 4.10260233641831e-06 1 1.88055413007262e-05 6.4225573639701 1.33291126395474 1.04006531497567e-19 64.3079935918247 6.73066331304643 9.55448082912909 2.96769187434108e-17 -34.5997080954681 26.6827117051961 -1.29670883820741 0.196683612410617 BORCS5 other 1.46722013983618e-15 1 4.20195492487954e-13 9.55448082912909 -1.29670883820741 2.82899325173537e-05 690.815018050541 147.326451542463 4.68900873412694 7.02356504105698e-06 342.536750902528 228.329244125151 1.50018781963285 0.136067366648405 FAM69B other 0.222670058844091 1 0.072223319317189 4.68900873412694 1.50018781963285 0.00157565107006174 87.9227001703581 35.4379351122932 2.48103338672965 0.0145093893417983 -68.5207913891896 55.4020535413301 -1.23679154488512 0.218620355428849 ZMYND19 other 1 1 1 2.48103338672965 -1.23679154488512 1.92344911277356e-06 128.683862068965 24.7102687514542 5.2077079113675 6.03755334967512e-07 45.4309701149422 53.0639150223922 0.856155639774618 0.393241884639284 STOX1 other 0.0170898453669931 1 0.00669262788811487 5.2077079113675 0.856155639774618 0.354576415274224 63.2627431686935 44.7611811485828 1.41333945050949 0.159655721197311 28.1286818079168 104.654338288048 0.268777026046413 0.788475578516839 RET other 1 1 1 1.41333945050949 0.268777026046413 5.25280533281639e-08 604.605849666753 138.718684148591 4.35850335070305 2.38312678181731e-05 -685.172893861875 303.504543094662 -2.25753752110449 0.0253802708046501 DDX21 essential 0.000533685021814146 1 0.232998305458278 4.35850335070305 -2.25753752110449 3.78587088492196e-09 289.398014674148 47.8724193405448 6.04519300801343 1.21875118583874e-08 -27.8425032369443 110.252166880175 -0.252534748520673 0.800987873707952 BMS1 essential 4.14022839975066e-05 1 0.000147834518842239 6.04519300801343 -0.252534748520673 0.191334515157452 49.3453019033691 27.0283455090453 1.82568710640669 0.0699691784703699 56.8439385923546 50.673785359317 1.12176223246963 0.263830615392969 STK32C other 1 1 1 1.82568710640669 1.12176223246963 1.70639707021203e-19 247.031199601866 25.1493056998315 9.82258526538653 7.63100095577e-18 -125.026589634308 81.7176074714842 -1.52998348217595 0.128155409146359 METTL17 essential 2.40431347192874e-15 1 1.08329689568111e-13 9.82258526538653 -1.52998348217595 5.03788536529107e-07 512.155035030932 90.8199836769804 5.63923284607179 9.82234109233295e-08 343.298446968651 289.101178239618 1.18746816965274 0.237159450042328 ARHGEF40 other 0.00471344554776633 1 0.00114184715198371 5.63923284607179 1.18746816965274 5.23184512789886e-10 473.4010398089 73.8449739876888 6.41074150676556 2.17083045702042e-09 -98.6538041657198 229.605031228472 -0.429667432102361 0.668112595064391 ZNF219 other 5.99150904046977e-06 1 2.71006474254429e-05 6.41074150676556 -0.429667432102361 0.51609580522359 15.4566476935534 35.831779794651 0.431367009457362 0.666804786162278 -51.2566326020765 68.6512311591001 -0.746623647335451 0.456429085825342 CASP7 other 1 1 1 0.431367009457362 -0.746623647335451 0.000326998517837416 12.0608533664508 6.05052381229718 1.99335689613157 0.0479658675427358 -17.644246093045 8.74384658063497 -2.01790435483186 0.0453152956057258 PPP1R36 other 1 1 1 1.99335689613157 -2.01790435483186 0.116719412796564 132.315372674301 117.596542901863 1.12516379656434 0.262404592949382 -202.863832707147 195.663559759819 -1.03679925355629 0.301579454184166 BTNL9 other 1 1 1 1.12516379656434 -1.03679925355629 0.00212348347248651 61.4889866205697 22.0165244956227 2.79285618548899 0.0058920940173042 -28.783507366319 42.2331798220365 -0.681537774034725 0.496561595171783 VWA2 other 1 1 1 2.79285618548899 -0.681537774034725 1.96963335019418e-24 363.05232578108 31.1296446674157 11.6625913870806 5.36398757376079e-23 -142.370155815312 102.670989492607 -1.38666391079792 0.167522647929338 METTL3 essential 2.83213579424421e-20 1 7.73111529006143e-19 11.6625913870806 -1.38666391079792 8.76727520113107e-10 286.458714475979 41.4317303887265 6.91399349697265 1.13827711108332e-10 269.919814074896 136.649062359973 1.97527746925807 0.0500011500479095 SALL2 other 9.92367880016025e-06 1 1.48021555525275e-06 6.91399349697265 1.97527746925807 0.107289346856683 21.5508542566328 16.0010638436323 1.34683883941936 0.180177734847955 -22.8853852003265 30.4701575525436 -0.751075381243509 0.453850183773896 PRAP1 other 1 1 1 1.34683883941936 -0.751075381243509 2.49980240570397e-09 209.337388954569 40.3196518399971 5.19194435967094 6.48903555800395e-07 -87.0473973990883 73.798763953917 -1.17952378516047 0.240008638248857 TRUB1 other 2.7630315990246e-05 1 0.00717297990581757 5.19194435967094 -1.17952378516047 7.2477406126296e-14 7.26122483964514 1.20581447828647 6.02184247278549 1.24419118568116e-08 -3.50094427222468 2.04660568801491 -1.71061005680112 0.0891932693919461 ERICH6B other 9.49309065442225e-10 1 0.000150845739351984 6.02184247278549 -1.71061005680112 3.43585772338345e-06 122.068060920821 32.4527624563263 3.76140740206926 0.000238573771400519 -50.9279966927758 49.0531916146189 -1.03821983884119 0.300774262323794 ZFYVE1 other 0.029730476880437 1 1 3.76140740206926 -1.03821983884119 0.00955377879788554 22.5323853128399 8.65997331711773 2.60190008533875 0.0101637219798103 -2.62129975318222 15.5261013091081 -0.168831807869531 0.866147648204792 C10orf82 other 1 1 1 2.60190008533875 -0.168831807869531 0.0328287798883956 94.9653185196473 61.0775245073877 1.55483247373853 0.122012381777286 -118.978430571237 109.503320447511 -1.08652806220856 0.278921448931813 HSPA12A other 1 1 1 1.55483247373853 -1.08652806220856 1.53311950028944e-07 35.3710152035311 9.65628132352081 3.66300587342813 0.000339685374239953 -28.9445368878302 17.1797867534112 -1.68480187229816 0.0940010333640029 FRAT1 other 0.00150215048638359 1 1 3.66300587342813 -1.68480187229816 2.8492542378952e-06 161.974063480029 61.6677557986742 2.62656004555806 0.00947412830627303 -233.469726941678 107.123545833617 -2.17944360527703 0.0307794012858975 UBTD1 other 0.0248568939713977 1 1 2.62656004555806 -2.17944360527703 0.732517676988808 -3.01971258227937 16.0127768166309 -0.18858144448395 0.850662880072269 -20.3971350128086 27.8159211248081 -0.733289935691436 0.464468211708939 ANKRD2 other 1 1 1 -0.18858144448395 -0.733289935691436 0.0343219787183476 -11.6651000041409 21.7967844981672 -0.535175268862331 0.593310761450087 -118.562362830759 47.8084013309777 -2.47994828377446 0.0142311136082146 E2F7 other 1 1 1 -0.535175268862331 -2.47994828377446 0.000205663483514425 63.2495219316839 16.6973401927978 3.7879998371816 0.000216370737174294 2.20910909547751 46.6034590244784 0.0474022560067307 0.962253261332093 ARHGAP42 other 1 1 1 3.7879998371816 0.0474022560067307 7.54323594580047e-05 75.0070888000262 37.2193122788264 2.01527336771069 0.0456156596947122 -144.949188671139 55.9094434325066 -2.5925707675148 0.0104435560868575 ISCA2 essential 0.562574536837799 1 1 2.01527336771069 -2.5925707675148 1.26684399127641e-08 361.694352995645 62.3069838298487 5.80503710440196 4.22348121008242e-08 -726.023775667924 407.488492486526 -1.78170375128307 0.0769969287743587 LARGE2 other 0.000134323468395038 1 0.00050014464489796 5.80503710440196 -1.78170375128307 4.31798908237478e-06 278.22950496166 60.4123441293613 4.60550751624346 8.92649926123815e-06 -34.8161930536762 120.010076669924 -0.290110580875926 0.772146110504937 PACSIN3 other 0.0369749405123752 1 0.0910145864675842 4.60550751624346 -0.290110580875926 6.36887958444129e-08 145.602312656227 29.1283341298094 4.99864880728692 1.54423259028985e-06 -59.461433941934 50.5190865318967 -1.17700928547849 0.240996069250898 TTC7B other 0.000643575282007792 1 0.0166746235099498 4.99864880728692 -1.17700928547849 0.00686010623759438 63.0650724997335 65.7614609935317 0.958997436293828 0.339124065198429 -318.126322071354 132.263902058599 -2.40523920071864 0.0173968292625911 SLC39A13 other 1 1 1 0.958997436293828 -2.40523920071864 0.000765700619165389 20.8082568156838 108.656286507089 0.191505319062476 0.848392194782197 -756.333126528876 218.536878887746 -3.46089470289074 0.000703805030392244 PSMC3 essential 1 1 1 0.191505319062476 -3.46089470289074 0.0404128076565546 13.9297160279363 5.54590956241785 2.51170991361485 0.0130880574984832 16.527794519091 11.1543087411278 1.48174081448457 0.140535273763464 RAPSN other 1 1 1 2.51170991361485 1.48174081448457 0.0151296113390949 3.91386496248954 9.27206823310016 0.42211347717627 0.673563121587456 -45.1580068537557 18.4229011841068 -2.45118868100497 0.0154192212491973 AGBL2 other 1 1 1 0.42211347717627 -2.45118868100497 0.0376063284793635 315.264085646569 126.716698801879 2.48794427749008 0.0138995469580422 64.8976670925547 221.136235014598 0.293473690950154 0.769550163592041 TC2N other 1 1 1 2.48794427749008 0.293473690950154 4.79850298216609e-13 320.667000892309 46.9797649862639 6.8256408048458 1.83104783253139e-10 -139.238004822577 81.9854719161842 -1.69832534433569 0.0914400348870833 CPSF2 essential 6.15120097283871e-09 1 2.36736174267983e-06 6.8256408048458 -1.69832534433569 8.79203911804084e-17 422.145151932372 48.5895775011132 8.68797741496518 4.7210735311337e-15 -61.9065288996159 85.2084807911676 -0.726530133207502 0.468602580332847 MOAP1 other 1.21048794577186e-12 1 6.5854254685784e-11 8.68797741496518 -0.726530133207502 0.00565590363625275 59.8761246386541 18.8479048636327 3.17680533045272 0.00179317577531382 18.3680586381993 32.9838908388035 0.55687968190188 0.578402607159765 IFI27L1 other 1 1 1 3.17680533045272 0.55687968190188 0.419382511069139 -96.4551010685979 2096.172556357 -0.0460148668467591 0.963356877856596 -4509.30479737556 3668.30834930526 -1.22926002069308 0.220813466979836 IFI27 other 1 1 1 -0.0460148668467591 -1.22926002069308 0.000330732451065592 248.381735408032 67.4502827123946 3.68244172477559 0.000318539556690134 -7.6586855337363 112.76141953445 -0.0679193785015845 0.945937348196394 CLMN other 1 1 1 3.68244172477559 -0.0679193785015845 0.473274804314429 1.73842458082425 2.50709421768831 0.693402173942702 0.489174126485817 -5.30345241766623 7.36397509902946 -0.720188803784141 0.472576139458494 PDZRN4 other 1 1 1 0.693402173942702 -0.720188803784141 0.122732305423921 67.5913470245209 37.2144182607092 1.81626773125951 0.0712740916999403 16.0026319919833 59.4746160920638 0.269066587453242 0.788238588023451 NELL1 other 1 1 1 1.81626773125951 0.269066587453242 0.00110868489790766 33.1290130796671 13.5640823363131 2.44240725308603 0.0156920775003411 -91.4805786761791 52.8927601008112 -1.72954821230394 0.0856639904288339 PTER other 1 1 1 2.44240725308603 -1.72954821230394 0.0740859971942234 4.20596982247439 1.87752022971054 2.24017283857593 0.0265017107695592 9.67198817712418 7.39180453617864 1.30847455851753 0.192649297365319 CACNB2 other 1 1 1 2.24017283857593 1.30847455851753 0.687872444088945 -3.13557944912387 6.56859785980312 -0.477359021825984 0.633774597951296 -21.9167456598868 25.8773619596405 -0.846946674628934 0.398322273910555 HACD1 other 1 1 1 -0.477359021825984 -0.846946674628934 9.72737596655715e-07 217.37778687476 43.0864768495206 5.04515111862015 1.25398649990163e-06 -50.8546603556351 179.485947442389 -0.283335052578188 0.777298083873469 ARL5B other 0.00888595794544996 1 0.013614531429432 5.04515111862015 -0.283335052578188 0.303751894993112 16.701635220126 17.82622157335 0.936913924883262 0.35025103070852 -37.7246289308173 49.3803482499679 -0.763960366173436 0.44604479404646 SMCO4 other 1 1 1 0.936913924883262 -0.763960366173436 1.17265551077371e-07 101.159162417272 22.4737501413546 4.50121416234519 1.30978096855133e-05 -111.532177498102 62.2618578063517 -1.79134033945777 0.0751650161582133 CEP295 other 0.00115987356570628 1 0.131502009242553 4.50121416234519 -1.79134033945777 0.0208440549280266 175.242078285182 79.4106833261731 2.20678214750261 0.0287901948483008 -70.7927539608574 134.271568848052 -0.527235620825806 0.598778967250809 ABTB2 other 1 1 1 2.20678214750261 -0.527235620825806 8.49990524625844e-09 52.9478650446291 14.2696875044433 3.71051328406051 0.000286088006520361 -53.3179239756005 24.7879869084921 -2.15095821102496 0.0329995483871069 R3HCC1L other 9.10169853769354e-05 1 1 3.71051328406051 -2.15095821102496 0.0508191901027001 204.520683883309 93.9147123203404 2.17772784295708 0.0309382460162913 -25.7988402678146 257.89884209039 -0.100034727022049 0.920446024706701 AMOTL1 other 1 1 1 2.17772784295708 -0.100034727022049 0.392370370917488 -135.369801628254 279.545295846534 -0.484249971791941 0.628892006536723 -692.241009058595 508.273053027323 -1.36194709700926 0.175190674461154 HTRA1 other 1 1 1 -0.484249971791941 -1.36194709700926 0.32758314852378 -4.032736879317 9.73473453169733 -0.414262645394795 0.67925819586942 -22.9630421483352 15.5221705587123 -1.47937055977307 0.141083978850291 LIPC other 1 1 1 -0.414262645394795 -1.47937055977307 9.57671785007027e-09 187.373558535817 40.0742267297944 4.67566248499834 6.32870621750953e-06 -209.726827854062 110.76231716128 -1.8934853768785 0.0601567941811851 CEP57 other 0.00010220273289595 1 0.065381863933091 4.67566248499834 -1.8934853768785 2.32063620189691e-10 72.6798999291567 14.8384470398265 4.8980799496122 2.41198455367097e-06 -48.7460651008066 30.0409463245108 -1.6226541126314 0.106695557060516 TCP11L2 other 2.70307704796952e-06 1 0.0257214032803472 4.8980799496122 -1.6226541126314 0.00145467512554761 159.649696969698 66.423070033082 2.4035278238447 0.0174343839874816 -113.592727272727 95.9567754061004 -1.18379058479184 0.238331895007854 SPRED1 other 1 1 1 2.4035278238447 -1.18379058479184 0.0184460422516686 34.7522785697593 12.1529810044264 2.85956824561 0.00483478232847259 27.6415400794578 17.2410696293001 1.60323812117102 0.110944503050615 GPR176 other 1 1 1 2.85956824561 1.60323812117102 0.894579953533863 14.7250122773915 32.5782114927403 0.451989584531761 0.651961326532257 2.37046705782009 86.562631726445 0.0273844153134257 0.97819130757531 JAM3 other 1 1 1 0.451989584531761 0.0273844153134257 0.00121104931524892 306.919804305997 82.5458621244658 3.7181731028893 0.000280476549050063 189.645847875835 228.520977634483 0.829883758764465 0.407889105982834 ADAMTS15 other 1 1 1 3.7181731028893 0.829883758764465 7.45044618653093e-11 983.122668710853 142.467938752838 6.90065903470698 1.55152230588438e-10 571.829725515474 211.800565966139 2.69984984651502 0.00777413005198935 GPT2 other 8.86752105120911e-07 1 2.01015229950381e-06 6.90065903470698 2.69984984651502 7.25213170773014e-06 255.84079300473 62.6367979782996 4.08451263893416 7.27703580294221e-05 -97.6955557966126 107.990526792681 -0.904667832430968 0.367142041064112 AMN other 0.0606713338668704 1 0.675527233587125 4.08451263893416 -0.904667832430968 0.37996368709088 29.5262088961932 21.400369176693 1.37970558603027 0.169716955327137 27.9637899012573 35.1366735652553 0.795857634312574 0.427364140514474 RAB8B other 1 1 1 1.37970558603027 0.795857634312574 0.0184361574438703 -3.19923640698205 23.0180531639967 -0.13898814049079 0.889644715154098 -114.399623514416 46.1990432802967 -2.47623360553889 0.0143814669292093 IKBIP other 1 1 1 -0.13898814049079 -2.47623360553889 8.65740644823948e-14 73.8492203536316 13.5106088170412 5.46601721311655 1.84556197954473e-07 -51.4685320561298 19.4008555836052 -2.65290011743727 0.0088279923502974 RPUSD2 other 1.13178274497835e-09 1 0.00211261479798485 5.46601721311655 -2.65290011743727 1.95011384578538e-14 206.462354669465 41.4610269875569 4.97967295241934 1.68055225260535e-06 -238.331592864638 76.2042886743368 -3.12753516909214 0.00210591816942776 HIF1AN other 2.58799608474178e-10 1 0.0181045894173175 4.97967295241934 -3.12753516909214 0.000150218895321844 121.800346274922 92.8858923825481 1.31129004793634 0.191698975536073 -447.836998950683 170.721853055338 -2.62319668475905 0.00958098721419138 NDUFB8 essential 1 1 1 1.31129004793634 -2.62319668475905 9.35020194827141e-11 303.389962209673 56.1117616818647 5.40688713232343 2.47495392969153e-07 -138.738529898818 87.9991935548004 -1.57658865149054 0.11699688628703 ZFYVE19 other 1.10874694702602e-06 1 0.00280882521480691 5.40688713232343 -1.57658865149054 0.00364874108235911 7.15600099601595 4.65399339565332 1.53760445872128 0.126266242342308 -13.652390438247 7.30114448371991 -1.86989731112555 0.0634601122499766 PPP1R14D other 1 1 1 1.53760445872128 -1.86989731112555 1.15165860754585e-09 3146.46341928205 645.46508279271 4.87472289851584 2.76200672910084e-06 -1792.28280754532 1012.60002497366 -1.76998100270829 0.0787755877554099 SPINT1 other 1.29573109934983e-05 1 0.0293297494563219 4.87472289851584 -1.76998100270829 0.827780606237756 -72.1494714035299 178.877840666516 -0.40334493716323 0.687268848706593 57.7218145393969 268.02349565693 0.215361024218864 0.829778402925883 FBN1 other 1 1 1 -0.40334493716323 0.215361024218864 0.0375168650417787 -13.2281182345168 6.89115286512021 -1.91957985745337 0.0568093717338019 20.7048081624788 18.9073946443475 1.09506405043852 0.275243781136899 AVPR1A other 1 1 1 -1.91957985745337 1.09506405043852 3.10204941066377e-14 7.73333169703749 1.29155491422986 5.98761354382582 1.42798994234278e-08 -5.49689162228214 2.59784387594047 -2.11594379215423 0.0359475093021779 DEPDC4 other 4.09687665666365e-10 1 0.000172601144330972 5.98761354382582 -2.11594379215423 6.29848986381528e-10 353.399892816253 87.9212920163742 4.01950295214539 9.2836317686892e-05 -185.681733291109 130.776199045375 -1.41984347799162 0.157770515665008 BRD7 other 7.18342768968133e-06 1 0.852515905318729 4.01950295214539 -1.41984347799162 7.57721936580123e-05 2518.02638029783 576.240516384416 4.36974893070176 2.33787188040526e-05 976.166707903778 996.452861599685 0.979641632356457 0.328872556300597 CKB other 0.564881703720482 1 0.228807520935263 4.36974893070176 0.979641632356457 7.85012843432063e-08 160.87154140906 30.9099607345942 5.20452105359725 6.43332464595722e-07 -24.0381508733163 52.756612162488 -0.455642428275717 0.649319468152887 TRMT61A other 0.000787760388384075 1 0.0071133270610349 5.20452105359725 -0.455642428275717 4.15473068014131e-13 103.991841519957 23.8620384356273 4.35804517709147 2.37903375266365e-05 -132.750273798784 41.6677564901092 -3.18592324091879 0.00174501921067 BTRC other 5.33592061250548e-09 1 0.232645710672978 4.35804517709147 -3.18592324091879 9.44491733703351e-15 129.336459356545 33.6769881065794 3.84049960011943 0.000178158862017112 -252.922416274031 58.9338950963016 -4.29162905083298 3.10199031018768e-05 POLL other 1.26032976945375e-10 0.44774128137249 1 3.84049960011943 -4.29162905083298 2.54518865907374e-09 379.286619337549 69.9490997288723 5.42232310076457 2.36032230717186e-07 -140.155704177344 119.387971961452 -1.17395162908536 0.242312834248125 BAG5 other 2.81166991167876e-05 1 0.00268345043102369 5.42232310076457 -1.17395162908536 1.48684952070488e-08 137.880232934013 48.7915205941658 2.82590563390844 0.00533610754397956 -253.972381301594 85.1994771689088 -2.98091478657893 0.00333811528925354 DPCD other 0.000156892361424779 1 1 2.82590563390844 -2.98091478657893 0.0013741787313531 158.26954255551 44.399000108305 3.56470961439298 0.000487194467368696 37.4996540972886 77.370569000725 0.484675950837808 0.628603938064463 LARP6 other 1 1 1 3.56470961439298 0.484675950837808 4.9589592993713e-07 332.609765235257 120.865479019086 2.75190044282813 0.00664621607677051 -588.409120844885 205.08293237454 -2.86912769401152 0.00470231956214797 API5 other 0.00464356948793129 1 1 2.75190044282813 -2.86912769401152 0.000432369542780437 64.8288758857243 16.8107690440771 3.85638965806656 0.000173417194946406 18.0116500506129 33.7415469975457 0.53381221826975 0.594300270660858 ASPG other 1 1 1 3.85638965806656 0.53381221826975 4.63577182072149e-12 142.618719271537 30.6057645306641 4.65986461892322 6.99613150589743e-06 -73.3082882619498 48.0995614805831 -1.52409473195599 0.129619031106061 ZNF319 other 5.76319152752096e-08 1 0.0719692048011668 4.65986461892322 -1.52409473195599 2.26049719837205e-08 86.6274724641023 25.3415901943366 3.41839134007707 0.000804936607052205 -102.121270880188 44.1903225710959 -2.31094196508498 0.0221540010862731 HPS6 other 0.000235702042874253 1 1 3.41839134007707 -2.31094196508498 8.82085820368929e-05 17.2658724423009 7.23529673072951 2.38633923180647 0.0182811563285911 -32.0624800239408 12.6328479189594 -2.5380246979639 0.0121823404752063 SENP8 other 0.651773212670601 1 1 2.38633923180647 -2.5380246979639 6.98233565216021e-10 804.16352883194 182.317622030928 4.41078333445752 1.9324738716074e-05 -575.777966978806 319.027931575173 -1.80478857802811 0.0730743241765264 NOLC1 essential 7.94240680433223e-06 1 0.19083179482123 4.41078333445752 -1.80478857802811 0.000372072861069945 29.6996285979572 20.108518554893 1.47696751090251 0.141753216320978 -88.9362813370473 35.1508999480937 -2.53012814660157 0.012420072903803 ALKBH3 other 1 1 1 1.47696751090251 -2.53012814660157 2.26586886955335e-09 241.72806129444 71.0037727264324 3.40443967992777 0.000847998186400395 -370.019863743263 106.595026529758 -3.47126761716191 0.000674556833516783 COPS2 essential 2.50854342548251e-05 1 1 3.40443967992777 -3.47126761716191 0.507378440681679 10.3436326070623 42.1951672898761 0.245137850408382 0.806682531808248 -48.3939706987229 59.2771113751489 -0.816402310707255 0.415556154277207 GABRB3 other 1 1 1 0.245137850408382 -0.816402310707255 1.00251905193694e-08 1037.10056929721 230.462730498758 4.50007932758916 1.31598700089543e-05 -1206.81774636827 506.317547725247 -2.38351949639152 0.0183429202554408 SGPL1 other 0.00010684848055544 1 0.132059295539856 4.50007932758916 -2.38351949639152 1.1695791576271e-79 500.558893388125 13.0806772185457 38.2670472655986 6.34648462273446e-80 -27.1217463596461 109.128915850441 -0.24852942181535 0.804060279003949 FRS2 other 1.7102756021981e-75 1 9.2804644638246e-76 38.2670472655986 -0.24852942181535 8.28292439767865e-26 1909.76931933565 147.446940106104 12.9522478931157 2.51915999760812e-26 -127.758236280326 1230.1140415292 -0.103858855331417 0.917418268905371 CCT2 essential 1.19489467360912e-21 1 3.64497260053919e-22 12.9522478931157 -0.103858855331417 0.00018439448794135 113.211256853355 219.050370784711 0.516827506147534 0.60600851358641 -1758.13617481138 481.295390962136 -3.65292543378977 0.000353531690209802 PCBD1 other 1 1 1 0.516827506147534 -3.65292543378977 0.00053276525660814 18.8299993931685 7.20082091919886 2.61497954253575 0.00979860478367097 -50.7060431580926 22.6935518951073 -2.23438108730017 0.0268792157241752 C16orf71 other 1 1 1 2.61497954253575 -2.23438108730017 0.162314533503453 25.3927825341432 23.6715557826156 1.0727128697131 0.285078053420091 115.591857558596 62.3902700802233 1.85272250640949 0.0658360791012931 CLMP other 1 1 1 1.0727128697131 1.85272250640949 0.0723149641158241 8.14611071367549 14.8964657918711 0.546848549682218 0.585269192081658 -77.5835044559458 39.9148469088752 -1.94372546719439 0.0537398584425138 SCN3B other 1 1 1 0.546848549682218 -1.94372546719439 2.2708706340592e-13 280.113974330684 35.5719840267784 7.87456707840123 5.14515807527536e-13 -372.790203517964 138.256588149675 -2.69636484240727 0.0077701616399263 COX11 essential 2.93623572983855e-09 1 7.01748109886807e-09 7.87456707840123 -2.69636484240727 2.82076812189884e-13 87.0007747582319 12.664105901144 6.86987107004313 1.46835348765976e-10 -77.0550787936363 33.9332735257102 -2.27078235570918 0.0245373381148979 ZNF202 other 3.63766257000074e-09 1 1.90357346140211e-06 6.86987107004313 -2.27078235570918 4.01160386087923e-13 49.768627202835 8.70381938880771 5.71802159254738 5.53881880430681e-08 -33.4076628594931 13.0666839667069 -2.55670550727435 0.011546892416863 FAM227B other 5.15450980084372e-09 1 0.000652195914207126 5.71802159254738 -2.55670550727435 1.97273818059237e-13 83.3768392428765 9.96564159841293 8.3664296392271 2.95058612911684e-14 -26.7127471009903 38.7331672330064 -0.689660800013975 0.491419188624144 STXBP4 other 2.55469594386712e-09 1 4.08036555795568e-10 8.3664296392271 -0.689660800013975 1.11164464937812e-06 677.268912754442 126.387973549151 5.35864998651203 3.77154906149949e-07 274.257434607241 245.285540162944 1.11811497092348 0.265611999525159 CYYR1 other 0.0101031380551666 1 0.00423205520190858 5.35864998651203 1.11811497092348 6.18853161974439e-14 172.005464995169 26.7912423595437 6.42021234725967 1.5786959908737e-09 -146.41658823677 72.5072105982801 -2.01933831171604 0.0451754740590876 CUL5 other 8.12306660407649e-10 1 1.97968477255562e-05 6.42021234725967 -2.01933831171604 1.27117573968844e-07 284.054757768676 90.4125722503399 3.14176171187971 0.00201668545515346 -357.878757410291 158.84767677713 -2.25296815585419 0.0256829594342026 WBP1L other 0.00125388774962867 1 1 3.14176171187971 -2.25296815585419 4.58411470348602e-08 21.4996721357709 18.8171464021932 1.14255752047851 0.254972882456328 -139.121329742104 32.6277378499048 -4.26389749672791 3.4675817941004e-05 BORCS7 other 0.000467579699755574 0.500198673798983 1 1.14255752047851 -4.26389749672791 0.520734589926317 111.587934755014 152.901906850952 0.729800805321473 0.466785806319773 -241.99673140391 463.166590916133 -0.522483132743332 0.602196723852851 C2 other 1 1 1 0.729800805321473 -0.522483132743332 0.00563562467165645 93.2018713540776 28.8354233373337 3.23220055636942 0.00156502914655848 49.0234046825826 129.325233927398 0.379070682447819 0.705268399611287 PLEKHF1 other 1 1 1 3.23220055636942 0.379070682447819 0.117253358280391 206.957459833855 116.777555269077 1.77223661993083 0.0782825508676146 518.466382875733 453.875902783736 1.142308678861 0.255053834009763 TMEM100 other 1 1 1 1.77223661993083 1.142308678861 0.000281065660824395 203.496947721118 108.874667891001 1.86909362538627 0.0635465671838036 -590.489030155597 235.745513211575 -2.50477314334144 0.0133147535333775 ANAPC16 other 1 1 1 1.86909362538627 -2.50477314334144 0.0671945354517672 -36.4611176851456 59.115877350603 -0.616773687869046 0.538288884819709 -199.585414387461 93.7146347643031 -2.1297144772471 0.0347742726181866 SMPD1 other 1 1 1 -0.616773687869046 -2.1297144772471 0.0128674811622877 28.8997521712921 38.6250956373799 0.748211795838868 0.45546618274157 -106.571376342405 61.2312105075509 -1.74047475885297 0.0837602496447898 APBB1 other 1 1 1 0.748211795838868 -1.74047475885297 0.0456134920334245 5.24720803345545 2.33887965564875 2.24347072359309 0.0263717327639522 -0.596508513877426 5.24269989811431 -0.11377887833938 0.909569392013719 SYNPO2L other 1 1 1 2.24347072359309 -0.11377887833938 7.74471589736995e-05 15.600913713811 3.82160557896314 4.08229300262948 7.20511288673398e-05 0.336686318604518 8.31498584141066 0.0404915083472226 0.967754765234316 NUDT13 other 0.576439204241246 1 0.669138833790984 4.08229300262948 0.0404915083472226 2.25810987050276e-12 8.55297272053852 1.42984024544172 5.981768066611 1.47024707634736e-08 -6.28628780314985 3.78664047328266 -1.66012269913236 0.0989115117475114 C11orf65 other 2.83663761932556e-08 1 0.000177620549293525 5.981768066611 -1.66012269913236 1.73928583402457e-06 481.528106435275 189.848006312224 2.53638748064256 0.0121959517533469 -969.620215670079 320.381784030513 -3.02645238899642 0.00290106874185783 TRIM44 other 0.0155266046403373 1 1 2.53638748064256 -3.02645238899642 1.09043557376113e-07 -27.1267645858837 137.007098628041 -0.197995321830221 0.843333893891512 -1021.35045436 221.103339999274 -4.61933525908453 8.5958693346295e-06 ILK og 0.00108160304561367 0.124897981432167 1 -0.197995321830221 -4.61933525908453 2.25405296203678e-05 269.203549571603 346.706198633844 0.77646015742542 0.438777904817116 -1698.4217870257 559.517713199026 -3.03551030996861 0.00286058604880316 TAF10 essential 0.17955785895585 1 1 0.77646015742542 -3.03551030996861 0.000748399130065062 501.28482252142 308.178653222908 1.6266046245547 0.106053923008167 -779.914365194169 497.341599277668 -1.56816635955429 0.11908380039351 TPP1 other 1 1 1 1.6266046245547 -1.56816635955429 0.0144594426167135 450.947428093004 189.521660783492 2.37939782834725 0.018670312075287 912.927927299369 315.295924660625 2.89546377195334 0.00438506655918461 DCHS1 other 1 1 1 2.37939782834725 2.89546377195334 0.0948051001295164 -2.77000379218808 4.88554739561066 -0.566979207831806 0.571570175714927 9.37978763746682 8.6762784805871 1.08108420660469 0.281383223585735 NETO1 other 1 1 1 -0.566979207831806 1.08108420660469 0.00601299803224484 4.9680800831051 2.65240210167963 1.87304936908287 0.0630074708031204 -9.18257241092261 5.69654271771285 -1.61195533255114 0.109073758027079 MSS51 other 1 1 1 1.87304936908287 -1.61195533255114 4.59300344587692e-05 70.1972879527697 92.6896675043589 0.757336711230176 0.450012932729488 -484.677496556973 176.227649509208 -2.75029201096873 0.00667249812573216 CYB5A other 0.351089183402832 1 1 0.757336711230176 -2.75029201096873 1.88518851960472e-06 397.520585544373 106.289940497772 3.73996432477733 0.000263114354486285 -458.5722378774 240.476615418973 -1.90693068878422 0.0584804435116789 USP54 other 0.0167744074474428 1 1 3.73996432477733 -1.90693068878422 0.00740710289327812 15.2819077512698 5.59561135336041 2.73105238842086 0.00705019049094486 -1.33941983097005 9.33865581007243 -0.143427475882062 0.88614008738902 RAG1 other 1 1 1 2.73105238842086 -0.143427475882062 0.00096566894621658 39.4289177893547 20.2424827460087 1.94783012953928 0.0532538484826615 -66.239124835589 33.7831859949994 -1.96071278906003 0.0517166774204873 C11orf74 other 1 1 1 1.94783012953928 -1.96071278906003 2.52835711419e-24 9.71592108479248 0.79658558270573 12.1969582374198 2.47611778859571e-24 3.88880942064408 3.8068033326041 1.02154198178236 0.308610250424827 WDR88 other 3.63350200880244e-20 1 3.5742760278379e-20 12.1969582374198 1.02154198178236 2.3759351886897e-13 177.557463464289 27.3613651989628 6.48934956911504 2.26505828696751e-09 25.637599670391 50.0818177817951 0.511914319525964 0.609692629625547 ATP9B other 3.07089623138144e-09 1 2.82611322464936e-05 6.48934956911504 0.511914319525964 1.86780401004756e-07 34.6143554829547 62.3588113815513 0.555083631584345 0.579637637982279 -407.481952851405 98.5260824061929 -4.13577748043895 5.78050912562206e-05 PPFIBP2 other 0.00181774686257829 0.831352822446964 1 0.555083631584345 -4.13577748043895 0.697090339222 -2.1311483441113 5.9658177673492 -0.357226524044202 0.72141448062416 -18.0384050106272 21.4690800948297 -0.840203908642147 0.402105122845517 MOGAT2 other 1 1 1 -0.357226524044202 -0.840203908642147 0.000276690834522015 -55.8525634928187 80.9657657106396 -0.689829374212652 0.491326406778678 -466.036674170604 128.148846886409 -3.63668254138642 0.00037470408896468 CYB5R2 other 1 1 1 -0.689829374212652 -3.63668254138642 0.118528168556413 51.8613239080063 26.6655664474583 1.94487988883318 0.0536112467753901 130.113642507117 78.2038326698026 1.66377577754394 0.0981908414851653 SERPINB7 other 1 1 1 1.94487988883318 1.66377577754394 5.63881856868059e-20 275.839110252985 27.5529265501985 10.0112454388624 1.95317999053304e-18 -14.8376057671436 102.995117187334 -0.144061254284085 0.885642923952356 KIAA0355 other 7.96652287383193e-16 1 2.78191426051621e-14 10.0112454388624 -0.144061254284085 0.0105978284639486 18.9929695642452 16.744370497674 1.1342898538278 0.258435522171086 -83.8356591070662 47.3969757983685 -1.76879764362417 0.0789073036335853 SERPINB8 other 1 1 1 1.1342898538278 -1.76879764362417 1.90868051379879e-05 165.356035384762 47.256583800702 3.49911106740445 0.00060857469436438 -31.7860532462453 74.7955221407251 -0.424972676658917 0.671442186247432 TUB other 0.153018916791249 1 1 3.49911106740445 -0.424972676658917 0.0244343563667966 84.7105012841244 79.3670690403367 1.06732555842615 0.287473791438117 -166.395013581069 125.618504178941 -1.32460591430099 0.187239086386849 RIC3 other 1 1 1 1.06732555842615 -1.32460591430099 0.0162725834383952 22.5494150099877 8.66466449650718 2.60245679669162 0.0101479353833511 8.29631038819665 13.7140278257022 0.604950674859217 0.546090727144776 LMO1 other 1 1 1 2.60245679669162 0.604950674859217 0.000155564185247381 213.512278011633 72.8470805739809 2.93096547355522 0.00389761633816504 -228.376021938975 130.152738720681 -1.75467703702408 0.0813163810092076 IDH3A other 1 1 1 2.93096547355522 -1.75467703702408 0.0027397696120285 276.559930423783 81.4346560774015 3.39609625367509 0.000871047157492851 81.7514231499052 121.486300772634 0.672927092437408 0.502008791539733 WDR72 other 1 1 1 3.39609625367509 0.672927092437408 0.0358914359164992 3391.04194478084 1419.32746817554 2.38918926098134 0.018111771628126 -57.2394626411666 2550.05396238394 -0.022446373090731 0.982121328863758 CRABP1 other 1 1 1 2.38918926098134 -0.022446373090731 0.550393808057822 -42.1134227728746 42.1472397934818 -0.999197645663799 0.319363503659239 1.4635244652599 86.8808238896521 0.0168451955188493 0.986583270637637 PLD4 other 1 1 1 -0.999197645663799 0.0168451955188493 3.20450385473799e-13 191.874133270655 24.0724320641969 7.97069995914666 3.20707385513831e-13 -20.8271477259372 97.3265400318335 -0.213992480562086 0.830834165361097 XRRA1 other 4.12579871297516e-09 1 4.38439066735959e-09 7.97069995914666 -0.213992480562086 0.0272807458539115 -9.85300254675013 32.1872013269591 -0.306115540977387 0.759924822658813 -116.950799859308 50.4255658471817 -2.31927590487998 0.0216772433916186 TRIM66 other 1 1 1 -0.306115540977387 -2.31927590487998 2.04779461270197e-10 198.136120578212 29.6733662829871 6.67723771845229 4.10308104019724e-10 -89.8745622282288 119.971511965164 -0.749132529515219 0.454912710147295 RNF169 other 2.3918241076359e-06 1 5.23881387212384e-06 6.67723771845229 -0.749132529515219 8.9347242790797e-05 2976.86537927532 2280.25377573615 1.30549740162771 0.193645605993614 -9150.55455677825 3572.32322713194 -2.56151360752561 0.0113695512629435 RPL27A essential 0.6592039573105 1 1 1.30549740162771 -2.56151360752561 3.84273009060901e-08 340.343158727022 191.60506947024 1.7762742899654 0.0776369692503026 -1075.23694010674 301.849494286068 -3.56216246990866 0.000488112534589658 ST5 other 0.00039430253459739 1 1 1.7762742899654 -3.56216246990866 0.0224738076823796 44.0212217490034 17.1137879776776 2.5722663975049 0.0110489067734839 25.5166265459474 31.5329556150334 0.809205037975642 0.419645679607134 CDYL2 other 1 1 1 2.5722663975049 0.809205037975642 0.101173139903964 57.9846661845808 30.3042598456326 1.91341634740297 0.0575623177353225 -44.1013817858668 97.8025506717929 -0.450922613806493 0.652683734353433 TMEM130 other 1 1 1 1.91341634740297 -0.450922613806493 0.00239088639775969 44.8738253077874 13.287213889823 3.37721855611563 0.000928580038356118 48.0564435055 19.851626196505 2.42078120098598 0.0166581589216559 PRTG other 1 1 1 3.37721855611563 2.42078120098598 2.14325155950928e-09 127.025759475359 20.1653061538732 6.29922295779088 2.94783380603966e-09 80.3836146205035 37.151574671703 2.16366642143243 0.0320217761658741 CENPN essential 2.3777232801196e-05 1 3.66032523695944e-05 6.29922295779088 2.16366642143243 0.00458761568877046 -18.6395243166092 15.836131790622 -1.17702508182253 0.24098978329632 -78.8428103901026 24.9045871092931 -3.16579472063131 0.00186239223119682 AKIP1 other 1 1 1 -1.17702508182253 -3.16579472063131 5.88976701867148e-14 419.517918796413 56.6307843128945 7.40794823674888 7.73008805211931e-12 137.091821776449 104.333789730909 1.31397337458965 0.190796507520954 ATMIN other 7.73562000232313e-10 1 1.03281706464366e-07 7.40794823674888 1.31397337458965 6.15329707923449e-20 51.4314109364452 5.92883468701329 8.67479254382016 5.28847658312673e-15 4.7820040505352 10.922995312345 0.437792374142162 0.662146248375443 C16orf46 other 8.69153212441872e-16 1 7.3737228998536e-11 8.67479254382016 0.437792374142162 9.92232528333695e-05 27.5357542897491 34.149935941275 0.806319354071416 0.421302138981411 -154.355725195169 53.6595968648318 -2.87657258372608 0.00459071576484147 TMEM41B other 0.728001006038432 1 1 0.806319354071416 -2.87657258372608 0.178897301148553 4.76261934612785 12.2823689938027 0.387760646869584 0.698725152473845 -26.1582891310638 22.6284364510393 -1.1559918948736 0.249463184007196 PKD1L2 other 1 1 1 0.387760646869584 -1.1559918948736 2.70024501072708e-10 133.005891805035 25.7844714524198 5.15837185379081 7.6628314885557e-07 -80.2004533351966 38.6218013184378 -2.07655910903642 0.0395255864494945 LEO1 other 3.13714465346273e-06 1 0.00842758207111356 5.15837185379081 -2.07655910903642 0.000160199569502376 35.9761606529555 14.6590361695837 2.45419686784068 0.0152414728456588 -27.0489226115918 23.2033684498144 -1.16573258189192 0.245536643077622 ZNF143 other 1 1 1 2.45419686784068 -1.16573258189192 7.33654492050302e-14 173.207951349379 32.840536294237 5.27421202252942 4.51056487867835e-07 -63.8918940678871 59.6148252280937 -1.07174505374173 0.28553328011278 TMX3 other 9.6072055733987e-10 1 0.00504016899347266 5.27421202252942 -1.07174505374173 0.973683769383734 -12.1828987414656 329.622889612382 -0.036960111464929 0.970564063907497 186.761084149049 924.617551067123 0.201987388119016 0.840189747491772 MFAP4 other 1 1 1 -0.036960111464929 0.201987388119016 0.000176409801587719 200.970059396338 94.1809612630277 2.13387139716137 0.0344473372959225 -224.073671086278 149.076345802194 -1.50307998147202 0.13487969023001 WEE1 essential 1 1 1 2.13387139716137 -1.50307998147202 2.09266683998297e-05 160.748354857284 34.9039811000043 4.60544470261772 8.49124023696312e-06 25.8507855556479 97.9083508585528 0.26403044611582 0.792104931308994 MAPK7 other 0.16716222717784 1 0.0867550015010522 4.60544470261772 0.26403044611582 0.502167871807516 13.2330472536351 20.0058517971837 0.661458826536839 0.509300192562464 48.41268174475 41.2222517912048 1.17443079019471 0.242023711891279 PRKCB other 1 1 1 0.661458826536839 1.17443079019471 0.000136528821594363 172.24498715718 47.7733019509075 3.60546539852283 0.000435311220766633 -85.5594912585957 106.860071906983 -0.800668479177814 0.424709913737151 NDST2 other 0.982870986657822 1 1 3.60546539852283 -0.800668479177814 0.000180406618814337 664.299516827862 160.870539956238 4.1294044080947 5.9266705553259e-05 57.4933241577747 529.179775875459 0.108646110034458 0.913623707187992 MCM7 essential 1 1 0.55556609785625 4.1294044080947 0.108646110034458 0.00169873569995707 -5.59503768844213 6.21707299038765 -0.899947241586634 0.369571895638862 -35.8065326633165 11.5890884470758 -3.08967636469727 0.00238332163645311 CCDC68 other 1 1 1 -0.899947241586634 -3.08967636469727 0.380935600655542 4.67264119477888 3.47015877488339 1.34652086486616 0.180125963369719 11.7755088991464 15.942934974438 0.738603583218941 0.46127924887205 CLEC4E other 1 1 1 1.34652086486616 0.738603583218941 2.55349865235493e-12 269.150727103334 38.4155067913694 7.00630421368807 6.78316437522717e-11 -216.318258597642 126.976802996645 -1.70360454423599 0.0904335309280893 ZNF3 other 3.20259800978355e-08 1 8.88119711648493e-07 7.00630421368807 -1.70360454423599 3.69650166427249e-11 52.8860222077075 8.33034445028308 6.34859969156621 2.22821973309479e-09 -56.6756368386675 27.4197254232419 -2.06696587817131 0.0403792347255453 ZSCAN21 other 4.45280590478264e-07 1 2.78059540492899e-05 6.34859969156621 -2.06696587817131 1.29977894695652e-11 159.70096396619 24.8995039030509 6.41382111820398 1.67705245852982e-09 -251.293242386171 114.395679671874 -2.19670221031917 0.0295461381907562 RIMKLB other 1.59131936475886e-07 1 2.10134673053786e-05 6.41382111820398 -2.19670221031917 0.511789220825901 -16.9664197720378 39.4154005794759 -0.430451537282421 0.66747693283878 -209.171056809023 180.955220190026 -1.15592717684169 0.249524619171551 A2ML1 other 1 1 1 -0.430451537282421 -1.15592717684169 0.210824700188549 0.497318590186598 8.14057174975346 0.0610913588718948 0.951369431490606 -14.9969546187514 12.414805862644 -1.20798945909232 0.228991133901695 BEAN1 other 1 1 1 0.0610913588718948 -1.20798945909232 1.23790061584183e-14 247.149174917492 36.8712008034886 6.70304111424837 4.2966042515395e-10 30.002053538687 57.0143617766788 0.526219229747811 0.599545424804304 TK2 other 1.64789329980865e-10 1 5.48332634581471e-06 6.70304111424837 0.526219229747811 2.16743763449314e-05 512.513051845636 142.721627980493 3.59099779828524 0.000442438723626984 -380.439530307196 254.228143674856 -1.49644931048136 0.136583240308736 TMED3 other 0.172874825727173 1 1 3.59099779828524 -1.49644931048136 0.810324409744744 -3.91552841609085 11.9960889809538 -0.326400414527396 0.744561722599265 -14.2145218860629 22.2159528754099 -0.639833995227661 0.523225129709864 SLC38A8 other 1 1 1 -0.326400414527396 -0.639833995227661 0.000121530866703999 42.6322884192792 49.8041394218493 0.85599889716348 0.393311281630193 -213.763898090254 93.5789129559672 -2.2843169613526 0.0237013935425935 SEC11C other 0.882557154004439 1 1 0.85599889716348 -2.2843169613526 5.35857691972195e-09 62.2482010001218 12.2762357849162 5.07062605270306 1.11151553525474e-06 -82.9165447005733 40.4980604674921 -2.04742014169124 0.0422942670428936 TMEM135 other 5.80762566559465e-05 1 0.0121177423653472 5.07062605270306 -2.04742014169124 0.000519971939736115 15.305615476746 12.7566891205889 1.19981096443303 0.232043483924684 -68.7720195417415 25.6279649029017 -2.6834756408596 0.00807758813245432 IQCD other 1 1 1 1.19981096443303 -2.6834756408596 3.95397573586492e-11 202.216712898752 31.810117516501 6.35699358211598 2.40872985133099e-09 -353.352219140079 163.536606112516 -2.16069189363614 0.0323282316061342 NDEL1 other 4.75900519568702e-07 1 3.00175914072868e-05 6.35699358211598 -2.16069189363614 0.00109037548894877 152.808027434651 40.5221623129324 3.77097417098798 0.00023083794062857 79.9928963852052 136.497093132083 0.586041025121312 0.558700348338183 CENPV other 1 1 1 3.77097417098798 0.586041025121312 0.368845783131598 -157.510745206042 373.356516071566 -0.421877584629728 0.673743522200222 -738.768825474026 585.291129854455 -1.26222453714229 0.208908445943203 CDH16 other 1 1 1 -0.421877584629728 -1.26222453714229 0.0898285114257022 -60.7043933023747 33.0195560772903 -1.83843759620152 0.0680582848705476 -112.186372314919 51.7629998456095 -2.16730816702144 0.0318554064807136 RRAD other 1 1 1 -1.83843759620152 -2.16730816702144 4.37881328824488e-06 160.045866721357 93.2611418610094 1.71610451606822 0.0882934098927693 -336.278764972729 146.20052615041 -2.3001200736225 0.0228782355797675 FAM96B essential 0.0374695053075114 1 1 1.71610451606822 -2.3001200736225 0.214489460140137 -10.5975954738331 10.1011147002943 -1.04915108760465 0.295807337498591 -65.2055634134844 41.7760928062644 -1.56083441589125 0.120684297674695 CFAP52 other 1 1 1 -1.04915108760465 -1.56083441589125 0.640214518340764 6.43059420176721 7.46981774500934 0.86087698807157 0.390627000078416 5.19856668370589 14.0842342523387 0.369105383407172 0.712549672466149 MC4R other 1 1 1 0.86087698807157 0.369105383407172 0.000872159792983116 101.89250961219 59.5805516249914 1.71016391814423 0.0893170107933893 -705.560948402715 272.272908167481 -2.59137404874931 0.0105098260395879 BLCAP other 1 1 1 1.71016391814423 -2.59137404874931 0.0725402856647536 3.67107436924256 2.84571003769596 1.2900380996705 0.198958752716838 -4.48537594332765 4.67748258032867 -0.958929481039881 0.339087668120024 CHRFAM7A other 1 1 1 1.2900380996705 -0.958929481039881 0.000901847664242766 87.7731917570798 23.8041674672694 3.68730357311456 0.000313622902875307 54.2229633225435 53.6560051946754 1.01056653632359 0.313809092919081 ATF7IP2 other 1 1 1 3.68730357311456 1.01056653632359 0.199828606027257 -379.449568781282 264.748092433504 -1.43324760263037 0.153801085302382 -1221.45375687675 737.718625096334 -1.65571766161827 0.0998022105680994 MMP10 other 1 1 1 -1.43324760263037 -1.65571766161827 1.4846482442148e-06 64.3982287134866 18.0054902638253 3.57658846106894 0.000465548126662278 -62.8032628962091 39.3099879328553 -1.59764136797707 0.112172667289308 TVP23A other 0.0133351105295373 1 1 3.57658846106894 -1.59764136797707 9.84156403078601e-05 4.39667536671978 1.4624194514041 3.00643933756381 0.00309357685175646 -4.89354146537337 3.87134980987269 -1.26404011667814 0.208150634076538 TMPRSS5 other 0.722370799859693 1 1 3.00643933756381 -1.26404011667814 4.36524253987324e-11 314.439864421606 42.12697071091 7.46409863124036 5.40953073909221e-12 -12.6026404985787 167.656959050131 -0.0751692060382084 0.940175780306854 COG1 essential 5.24178324187979e-07 1 7.25418072112265e-08 7.46409863124036 -0.0751692060382084 1.72748803842423e-06 126.72128406621 89.4263762090317 1.41704594816637 0.158476348611152 -482.186965621018 138.140072829899 -3.490565451017 0.000627916392196273 PLEKHA7 other 0.0154230132070516 1 1 1.41704594816637 -3.490565451017 6.71636498801471e-07 91.2224319647634 22.3713655636844 4.07764254287837 7.3360492093207e-05 -40.9797074091554 44.0681886594739 -0.929915856669672 0.353898896178537 ZNF606 other 0.00621733906940522 1 0.680858727117054 4.07764254287837 -0.929915856669672 0.0278564650976931 -10117.7725311888 3841.55685853143 -2.63376878275769 0.00940110461347416 -10922.0033062327 6016.16039426909 -1.81544416878195 0.0716112097322985 B2M other 1 1 1 -2.63376878275769 -1.81544416878195 6.73843982878606e-13 621.981580401548 90.732128989501 6.85514147335306 1.61631199060168e-10 -247.187879904218 159.225169801499 -1.55244224397675 0.122609116913451 ZNF592 other 8.59757537754813e-09 1 2.09312402782917e-06 6.85514147335306 -1.55244224397675 7.65681971897291e-08 512.836021220161 143.581240694858 3.57174808309431 0.000485657711193556 -546.506324786324 229.098857586564 -2.38546071570797 0.0183868181829715 CASC4 other 0.000769280677165208 1 1 3.57174808309431 -2.38546071570797 0.892709135028031 -40.490972507182 242.648060724005 -0.166871197677683 0.867696135760803 -303.466557242513 645.893864546738 -0.469839665461869 0.639151897682212 HTR3A other 1 1 1 -0.166871197677683 -0.469839665461869 0.422512585424953 199.372735799285 208.748075657919 0.95508777827491 0.341069981370715 -168.559118353948 555.657032251111 -0.303351003533729 0.762042712286518 NNMT other 1 1 1 0.95508777827491 -0.303351003533729 2.57587488610036e-14 626.473497225817 102.371154168573 6.11962913101686 7.3589201985214e-09 -48.3322952988735 162.180404962531 -0.298015628398757 0.766090331674048 AP1G1 other 3.40839764928799e-10 1 9.01026189106961e-05 6.11962913101686 -0.298015628398757 0.00225438588811479 362.080783232322 104.801321671287 3.4549257343147 0.000713592792109526 -136.794679257635 404.507082361559 -0.338176227864818 0.735697025773877 SLFN5 other 1 1 1 3.4549257343147 -0.338176227864818 0.00966127593315759 11.978604896626 9.94003495332361 1.20508679827336 0.230325806427911 -36.0194552806681 19.4616847053337 -1.85078814224118 0.0664353543529031 CATSPER2 other 1 1 1 1.20508679827336 -1.85078814224118 7.67353063681588e-05 113.339425846826 41.5635244785027 2.7268964138363 0.00712563282803684 -120.334657792788 83.8493249022179 -1.43512971551194 0.15325200900508 ZNF667-AS1 other 0.57137109121731 1 1 2.7268964138363 -1.43512971551194 0.1124930286039 59.1192703053294 34.3469531424046 1.72123769058109 0.0871901541098258 -18.9420626355781 87.9194407092408 -0.215447942830091 0.829699518266954 C16orf45 other 1 1 1 1.72123769058109 -0.215447942830091 1.89322630105631e-83 135.389594501194 3.41204588942786 39.6798867567096 2.04826877088205e-83 11.9677059567317 19.7661961264758 0.605463280853595 0.545751042412715 SAAL1 other 2.76884346529485e-79 1 2.995593077415e-79 39.6798867567096 0.605463280853595 0.411973497350526 4.88232853540992 6.00985586764845 0.812386959509611 0.417874426504512 -16.7702805348993 21.7007381159808 -0.772797701408571 0.440874541828431 YPEL4 other 1 1 1 0.812386959509611 -0.772797701408571 3.93678681850395e-05 1112.20759854985 670.016167482993 1.65997128506318 0.0989420210000906 -3522.89822667694 1081.86027908358 -3.25633383052119 0.00138633029591744 PPIB other 0.303211320761174 1 1 1.65997128506318 -3.25633383052119 2.22045191460096e-63 27.1431828465106 0.941483025021857 28.8302413587121 2.19899768959088e-64 22.0639767142293 5.45953294639466 4.04136707862526 8.32188595598398e-05 LDHC other 3.24385820204054e-59 1 3.21295552426123e-60 28.8302413587121 4.04136707862526 0.00112355835008767 142.080138924621 59.6799481175785 2.38070144841114 0.0184944096954205 -157.943603219523 96.9334503876988 -1.62940246723712 0.105258488854672 FAM96A other 1 1 1 2.38070144841114 -1.62940246723712 0.00408477934855746 39.0041152263374 43.831301717737 0.889868968015472 0.374951788501967 -472.628875171469 164.979069784761 -2.86478082212538 0.004767982077802 FAM111A other 1 1 1 0.889868968015472 -2.86478082212538 0.0383062307507348 90.088575928083 47.3393343894182 1.90303850043613 0.0588894705523464 -60.2540478026214 76.4377756831766 -0.788275787254271 0.431739322638758 PCLAF other 1 1 1 1.90303850043613 -0.788275787254271 3.24539855894361e-07 109.281357730045 19.2159947403614 5.68699977318947 6.31740929251946e-08 40.5676291200649 34.6378518623485 1.17119356250155 0.243329940834431 KIF7 other 0.00308776064675287 1 0.000742232417778112 5.68699977318947 1.17119356250155 0.000990478288155546 18.1815988316719 28.1506873207166 0.645866959642288 0.519339382846599 -113.998920566385 47.4403815164428 -2.40299333442066 0.0174669070502592 LDHD other 1 1 1 0.645866959642288 -2.40299333442066 0.41713825011277 23.2928489348536 17.6919471537107 1.3165791607041 0.189935742402084 18.9578725152219 31.890675083272 0.594464446604522 0.553073862877223 PLIN1 other 1 1 1 1.3165791607041 0.594464446604522 1.13918319284826e-05 40.8797843189251 9.5635602119955 4.27453619914997 3.34486545264878e-05 -15.7024557900593 17.238825591681 -0.910877351043965 0.363783548039239 PEX11A other 0.0936180747882703 1 0.322311235017236 4.27453619914997 -0.910877351043965 3.42967543181722e-19 256.499124680172 30.4627062482437 8.42010301349901 2.44614695967988e-14 31.1155889377162 53.8494420166619 0.577825651899765 0.56422575119394 TMEM170A other 4.82349552730774e-15 1 3.3874243097647e-10 8.42010301349901 0.577825651899765 0.543381817414275 -10.4546981348891 29.7394671864445 -0.35154288640566 0.725661628476333 46.5761669292485 53.6069702759434 0.868845351443969 0.386283776180485 MESP1 other 1 1 1 -0.35154288640566 0.868845351443969 0.209282650353832 -965.922749483984 662.107479204501 -1.45886095508921 0.146626876608456 559.750384125874 1216.42079911537 0.460161799710222 0.646044954568229 ANPEP other 1 1 1 -1.45886095508921 0.460161799710222 0.288640893823539 8.69675165809056 9.62682145815805 0.90338765457426 0.367713052491257 -12.5404208434671 19.5759532178109 -0.640603331236889 0.522720308732059 SCNN1G other 1 1 1 0.90338765457426 -0.640603331236889 0.00947295884492574 71.9550330111768 23.3235420031483 3.08508171706785 0.00241045465593425 37.0023006632784 38.4679103957712 0.961900458917208 0.337597798470309 RBPMS2 other 1 1 1 3.08508171706785 0.961900458917208 0.0225997045329158 181.074792761356 119.366072613211 1.51697034841804 0.131297999182178 -218.072792968405 197.283727593355 -1.10537648304122 0.270698343628859 NAV2 other 1 1 1 1.51697034841804 -1.10537648304122 6.22603759550581e-06 49.2861337783191 16.2054092488427 3.04133842111015 0.0027664103069432 -67.6124231998502 26.7278542353102 -2.5296614761737 0.0124158846274073 ANKDD1A other 0.0524170105165634 1 1 3.04133842111015 -2.5296614761737 8.00044587366324e-12 39.6391712845299 11.7488125296642 3.3738874617708 0.000940491114486362 -53.1008707970501 21.8354795444974 -2.43186190112466 0.0161836431977037 C18orf54 other 9.86534980681413e-08 1 1 3.3738874617708 -2.43186190112466 1.17662711535516e-08 323.305046292558 69.5239671546811 4.65026751959147 7.02071108167249e-06 -201.143473887473 141.825050562693 -1.4182506763751 0.158112158400764 DCTN5 essential 0.000124910734566104 1 0.0722009927639199 4.65026751959147 -1.4182506763751 0.000427289860432318 481.034593988698 127.657983018884 3.76815129467885 0.000232747165212436 176.406904602823 260.41522998973 0.677406250816362 0.499151606459996 PLK1 essential 1 1 1 3.76815129467885 0.677406250816362 4.48314728138627e-15 343.289072198872 42.8670203625287 8.00823265287996 2.5851139861587e-13 -55.5647220934233 71.2435732233919 -0.779926098304954 0.436623693655223 CLPX other 6.01952185471734e-11 1 3.53746997865956e-09 8.00823265287996 -0.779926098304954 3.69087346494795e-08 131.007370203782 23.6121720877524 5.5482981284782 1.55151388133792e-07 -35.2167053634746 58.6839730426401 -0.6001077217094 0.54947909935241 ZBTB39 other 0.000379089613584804 1 0.00178455126631488 5.5482981284782 -0.6001077217094 0.451970955236819 9.59907439359563 7.74525811894474 1.2393485467084 0.217077732551015 13.3514049295516 15.7998984997002 0.845031056990964 0.399387649369599 CHP2 other 1 1 1 1.2393485467084 0.845031056990964 0.000375232734695516 162.582609799355 43.6493042772938 3.72474687721264 0.00029197063265541 -25.8827651976439 109.259888076608 -0.236891741821081 0.813119481132026 NEMP1 other 1 1 1 3.72474687721264 -0.236891741821081 2.44405387143528e-10 446.959099032964 75.4450134738829 5.92430272661677 2.71936503024435e-08 -335.294948011896 188.848685324468 -1.77546879627896 0.0781969840951692 NAB2 other 2.8434122740278e-06 1 0.00032474657191178 5.92430272661677 -1.77546879627896 1.57548376925767e-14 651.06331391364 85.402287917881 7.62348796252008 3.40156615897275e-12 19.8426675278108 131.945353250443 0.150385497018207 0.880676935059463 VPS39 other 2.09381792934345e-10 1 4.57782773674553e-08 7.62348796252008 0.150385497018207 0.0134160831490851 590.140012337587 251.468581057263 2.34677433600822 0.0204839574872958 -509.728484404519 598.494216638606 -0.851684895582396 0.39599212583301 STAT6 other 1 1 1 2.34677433600822 -0.851684895582396 0.0185461466285503 143.89293571254 98.8321193169729 1.45593291641404 0.147572955986801 -605.516638148782 321.498986148262 -1.88341694449245 0.0616464899485097 PATL1 other 1 1 1 1.45593291641404 -1.88341694449245 0.146165844044623 5.61941205549604 6.24515245607616 0.899803823048177 0.369686389148475 -29.5216743447136 19.9274202950814 -1.48145991340385 0.140609986507162 ATP23 other 1 1 1 0.899803823048177 -1.48145991340385 0.379879153458295 14.5285136151467 10.4163417116122 1.39478081819746 0.165090505119372 13.2186708369644 20.7009497918242 0.638553833031619 0.52406172369085 ELFN2 other 1 1 1 1.39478081819746 0.638553833031619 0.00125673751763199 112.515428308259 53.5974344588235 2.09926891919985 0.0374792169638159 -402.298004298434 177.009876741693 -2.27274325988882 0.0244717708985681 STX3 other 1 1 1 2.09926891919985 -2.27274325988882 0.00596178988550444 46.2320810217074 41.1416821519262 1.12372850606797 0.262899840089615 -347.840026808654 136.220343337605 -2.55351013135076 0.0116488817943013 MRPL16 essential 1 1 1 1.12372850606797 -2.55351013135076 2.24505152287918e-06 427.364599297089 98.0119393982474 4.36033203628997 2.56782899687065e-05 -600.75496680696 333.884541014543 -1.79928955375263 0.0742232542712209 PIP4K2C other 0.0198238049470231 1 0.250543075224669 4.36033203628997 -1.79928955375263 5.01741413397748e-13 241.496374046694 42.4851381031627 5.6842553614935 6.34429771301895e-08 -141.773880027529 68.0767369779097 -2.08255986290196 0.038934059264006 MTMR10 other 6.42931447127874e-09 1 0.000745264652348336 5.6842553614935 -2.08255986290196 9.39568671814801e-06 816.59014592526 208.27392467963 3.92075074775372 0.000132204112508476 -1435.85404727466 913.327081663642 -1.57211373242018 0.117963236243597 YWHAB other 0.0778432644598562 1 1 3.92075074775372 -1.57211373242018 1.32232028736651e-07 573.37287831411 99.8304990787655 5.74346400754466 4.80398697437339e-08 275.302092177287 161.80599628932 1.7014331884526 0.0908797730502241 SCG5 other 0.00130288217914222 1 0.000567446941412984 5.74346400754466 1.7014331884526 0.900695768339316 -13.8046534062197 52.2943059539528 -0.263980048198273 0.792148216049067 15.6819651798431 84.0885078356428 0.186493559981997 0.852303173844793 GREM1 other 1 1 1 -0.263980048198273 0.186493559981997 0.01442582931458 16.750235074012 5.85623822167466 2.86023799578666 0.00483733177453201 4.96981843561881 19.3764227738013 0.256487923164974 0.797925549525538 NYAP1 other 1 1 1 2.86023799578666 0.256487923164974 2.11592464598334e-05 366.165908971147 92.2270705717231 3.97026498512047 0.000110737092149399 -382.757098305604 305.416064083227 -1.25323171672235 0.212058470841525 TSC22D4 other 0.16889310524239 1 1 3.97026498512047 -1.25323171672235 0.852015624747686 5.924935770935 28.5199575215671 0.207747005459405 0.835704598779584 53.3777786052054 94.4297413804187 0.56526447944158 0.572727276023306 MS4A7 other 1 1 1 0.207747005459405 0.56526447944158 0.843200530526684 1.17932010276652 3.67714842823779 0.320715936759639 0.748866174701685 -4.43580444576833 12.1750593363727 -0.36433534516883 0.716113951177346 MS4A14 other 1 1 1 0.320715936759639 -0.36433534516883 9.34649100784614e-10 284.197836348491 45.5773463072591 6.23550643849633 4.03541794353989e-09 -26.2449575314863 77.137796992402 -0.340234729986798 0.73413746894909 DIS3L other 1.05643387861685e-05 1 4.98979428718707e-05 6.23550643849633 -0.340234729986798 4.28452693071342e-09 216.271123861304 56.5940852909712 3.82144393268968 0.000202259565775267 -244.453811770549 93.6621175500236 -2.60995392977304 0.0100855180353848 CCNDBP1 other 4.66756363831919e-05 1 1 3.82144393268968 -2.60995392977304 2.82852767119859e-06 3.68097578189327 2.66511663631165 1.38116873826112 0.16952600495114 -15.8957039980134 4.41071653320932 -3.60388247087087 0.000440832127678701 EPB42 other 0.0246817324588789 1 1 1.38116873826112 -3.60388247087087 2.37491839140106e-06 312.628268493719 77.9226006274887 4.01203586605441 9.3410622625118e-05 -216.365050238987 131.287666004539 -1.64802267283438 0.101373625128224 SMAD3 ts 0.0209135313546778 1 0.857416105075958 4.01203586605441 -1.64802267283438 0.135563912181738 -53.8576281199231 28.8867644042303 -1.86443962246031 0.0641757614599123 -124.917530645399 95.7826938072131 -1.3041764193522 0.194132027638814 MS4A8 other 1 1 1 -1.86443962246031 -1.3041764193522 0.682471291551922 0.536043185295714 3.81308982707181 0.140579742310282 0.888391820555659 -6.26734207049922 9.83362795223247 -0.637337725297649 0.524882988840601 CCDC178 other 1 1 1 0.140579742310282 -0.637337725297649 0.000561232416885502 36.1956874907694 9.13400507300193 3.96274002493778 0.000113345623507955 33.1955102643627 30.2865214981556 1.09604895584936 0.274779576230492 MS4A15 other 1 1 1 3.96274002493778 1.09604895584936 0.588081734561981 46.8501122659001 45.7333712930853 1.02441851412305 0.307443079092367 57.2775051455204 89.8365044902979 0.637574953194068 0.524814535434061 MAP1A other 1 1 1 1.02441851412305 0.637574953194068 6.89564571961966e-09 137.211837681353 23.3002043537397 5.88886842356515 2.62584462235551e-08 -28.6909930503993 42.155210813463 -0.680603714149528 0.497215155625137 RCCD1 other 7.42661044003038e-05 1 0.000313893466156378 5.88886842356515 -0.680603714149528 1.51739213236276e-13 128.811551653973 34.6005368623485 3.72281945122485 0.000277530911485852 -152.304153828266 53.0895715264578 -2.86881489997265 0.00471074190864746 AKTIP other 1.97109237993922e-09 1 1 3.72281945122485 -2.86881489997265 0.00995560023406977 89.8133252525449 29.8414896370119 3.00967968908465 0.0030720166059718 91.1822335656762 76.5377886090071 1.19133613895589 0.235415896924998 MAPRE2 other 1 1 1 3.00967968908465 1.19133613895589 0.00503182909463543 -193.455526553404 86.2606667142079 -2.2426852692241 0.0264030719673253 -552.899382736975 175.062351379643 -3.15829976222556 0.00192394721500878 EVA1C other 1 1 1 -2.2426852692241 -3.15829976222556 1.41863826151923e-05 446.971806396557 99.1112363295894 4.50979952374093 1.41012482951954e-05 -199.166332910614 333.859653475739 -0.596557058743509 0.551817211683927 MBD6 other 0.115292731513668 1 0.140956077958773 4.50979952374093 -0.596557058743509 0.0194507419094281 18.3260801113671 9.34435160841222 1.9611933368249 0.0516484073296662 -44.1578197245654 30.7704238297385 -1.43507349683915 0.153280899979552 CNPY4 other 1 1 1 1.9611933368249 -1.43507349683915 3.73785232844063e-08 1542.26131206161 600.20442030681 2.569560069673 0.011252056523763 -4065.16515380736 1135.2104099059 -3.5809794539713 0.000474335325424308 PDIA3 other 0.000383765298561 1 1 2.569560069673 -3.5809794539713 1.66869242330392e-15 741.634178743962 115.546629615109 6.41848387282589 1.61473007486853e-09 -44.3340982286634 180.148987768975 -0.246096848934382 0.805934964449594 NUDT21 essential 2.25740711024554e-11 1 2.02390267584022e-05 6.41848387282589 -0.246096848934382 0.272547148690363 -14.4500640488961 16.7455069148587 -0.862921864495737 0.389522289092468 -47.7514695745556 30.5454500402583 -1.56329238926321 0.12003645860667 NKX3-1 other 1 1 1 -0.862921864495737 -1.56329238926321 9.12622275147131e-08 17.8992327205372 2.98435069591977 5.99769750418715 1.40323947728393e-08 18.3496333949756 16.5758657613327 1.10700904913097 0.270038837673556 SGSM1 other 0.000911070817279381 1 0.000169679717593172 5.99769750418715 1.10700904913097 1.11459875063259e-10 138.113991589971 18.8931393976902 7.31027219366501 1.38616326048134e-11 92.784307891675 34.2371830704601 2.7100450320555 0.00749554558426484 DUSP18 other 1.31745572324772e-06 1 1.84359713644018e-07 7.31027219366501 2.7100450320555 0.0312577755802003 35.6049584696703 45.0514914119577 0.790316976281498 0.430573955298197 -105.18910982465 67.3019722788262 -1.56294245566624 0.120145738485442 TEF other 1 1 1 0.790316976281498 -1.56294245566624 0.566042968691021 17.4926848049282 16.8715967931079 1.03681263957623 0.301448440789476 10.0537588409766 25.0810540564647 0.400850730529215 0.689085621679643 MEI1 other 1 1 1 1.03681263957623 0.400850730529215 0.990256461915467 -4.47416959330853 59.0729907636881 -0.0757396829831542 0.93972324742431 -11.5954889502516 82.8596738113778 -0.139941281649836 0.888886900271817 PBX3 other 1 1 1 -0.0757396829831542 -0.139941281649836 0.216333868855669 1.59969177925648 1.83262381979259 0.872896969896161 0.384060848849539 11.5847378491155 7.48809380492743 1.54708770361455 0.123868368502516 GNGT2 other 1 1 1 0.872896969896161 1.54708770361455 8.70709025928812e-10 1206.87641919417 176.187562019896 6.84995243340667 1.60702711512865e-10 -563.914482419161 722.893875867276 -0.780079208365981 0.436526224133121 PHB essential 9.86077971864379e-06 1 2.08126081680312e-06 6.84995243340667 -0.780079208365981 1.6464658524628e-08 299.299802449625 58.9091751195858 5.08069926020939 1.2771880504131e-06 -117.423192414065 164.374439618909 -0.714364062236825 0.476282838937838 SNRPD1 essential 0.000173306995630235 1 0.0138625990991837 5.08069926020939 -0.714364062236825 0.0172722971953193 8.3673034767457 13.0712697313394 0.64012935611637 0.523033616638848 -35.7692619956158 18.1268239043698 -1.97327795450106 0.0502420973006566 TTC16 other 1 1 1 0.64012935611637 -1.97327795450106 6.58761587391721e-12 298.991682262425 39.5374940650499 7.56223148008578 3.11638364027037e-12 -214.173788729464 161.861828474784 -1.32318898623359 0.18769633701101 SAMD14 other 8.14690455127341e-08 1 4.19714548671614e-08 7.56223148008578 -1.32318898623359 4.17965345701287e-09 43.6216385485575 9.26755335321489 4.70692068186748 5.58895547881692e-06 -16.2518103886954 12.7236475173098 -1.27729178025293 0.203434130038495 PIP5KL1 other 4.55624023348973e-05 1 0.0580133578701196 4.70692068186748 -1.27729178025293 9.69372444870658e-09 54.4034571533652 21.2448319630285 2.56078547705349 0.011386274254729 -493.664720485472 86.4838100836259 -5.70817497527133 5.54915503649353e-08 TMEM92 other 0.000103412652418802 0.000811230974784989 1 2.56078547705349 -5.70817497527133 6.08396971693029e-06 571.47127500375 181.61595976948 3.1465917187515 0.00198340341432089 -395.918724453818 250.620046329607 -1.57975680817296 0.116214355702247 FAM102A other 0.0512817807440054 1 1 3.1465917187515 -1.57975680817296 5.44825381604789e-06 291.626618276368 70.173384276686 4.15580096759358 5.31168430814963e-05 -744.811155950381 281.435551678444 -2.64647146214623 0.00896202716987583 ACSF2 other 0.0461521580757417 1 0.500998063944673 4.15580096759358 -2.64647146214623 1.2405165159841e-06 452.20325268904 124.703879898512 3.62621638602631 0.000389694095847867 -210.190464808293 172.434690528937 -1.21895695212803 0.224712393608432 GOLGA2 other 0.0112229529201082 1 1 3.62621638602631 -1.21895695212803 4.29184957115708e-10 222.169740624697 61.1964305389959 3.63043626348639 0.000383871890037056 -239.114325398107 84.6195609154684 -2.82575710404564 0.00533845903347155 TRUB2 other 4.93691456170198e-06 1 1 3.63043626348639 -2.82575710404564 1.54410724765577e-08 207.406248981959 80.2602147086409 2.58417261572101 0.0106841259184176 -360.108557411015 110.120819899641 -3.27012237775926 0.00132467045541152 COQ4 essential 0.000162764344975394 1 1 2.58417261572101 -3.27012237775926 1.00185317322153e-06 276.04027860126 67.7662454018766 4.0734185133653 7.37169416790396e-05 -63.1477446719789 92.9785016432499 -0.679165006490114 0.498046221965968 SLC27A4 other 0.0091379027929536 1 0.68387206795645 4.0734185133653 -0.679165006490114 2.20800034966262e-08 187.308660355353 95.0369120531252 1.97090431821531 0.0505157357053962 -489.535131384341 130.395149253115 -3.75424342230773 0.000245426804588279 URM1 essential 0.000230471076497784 1 1 1.97090431821531 -3.75424342230773 0.155894067290759 383.498159381292 241.778654960055 1.58615391191026 0.114742394920702 -0.271799115198847 331.731777881318 -0.000819333971966013 0.999347319699506 CERCAM other 1 1 1 1.58615391191026 -0.000819333971966013 1.08629873903739e-07 101.545710497043 27.8957827291453 3.64018143828417 0.000369360401140923 -64.9730079624944 38.4724185375635 -1.68882047015205 0.0932389640416366 DOLPP1 other 0.0010779342387468 1 1 3.64018143828417 -1.68882047015205 0.00226469499702441 69.234857189757 19.6436020532104 3.52454997826845 0.000556030684876899 -11.701571277449 77.1842150241615 -0.15160575609645 0.879692527712401 CCDC103 other 1 1 1 3.52454997826845 -0.15160575609645 3.59961549864217e-06 52.135117577847 45.1029391820131 1.15591397197987 0.249506491276883 -215.660533947599 61.6084020374881 -3.50050523654828 0.00060762417455675 ENDOG other 0.0310718809842792 1 1 1.15591397197987 -3.50050523654828 0.253545224697129 202.170127335952 121.790953605502 1.65997655286294 0.0989152181087485 147.426700522853 167.90210815599 0.878051515505008 0.381257503888403 PRRX2 other 1 1 1 1.65997655286294 0.878051515505008 4.35491988203853e-08 1032.39600011033 195.582229272293 5.27857773148201 4.55311376884542e-07 -214.755845902829 336.147907469828 -0.638873070843391 0.523892992407852 C15orf39 other 0.000444942164347876 1 0.00508628339117722 5.27857773148201 -0.638873070843391 0.999933495557281 -0.249611878179364 23.0880321247287 -0.0108113102420719 0.991388550202257 -0.0200378212327396 40.2767599165674 -0.000497503306478663 0.999603719762173 ISLR2 other 1 1 1 -0.0108113102420719 -0.000497503306478663 1.15186571234128e-08 224.364622036074 35.0409025198032 6.40293502455524 1.77411764760223e-09 132.023069648044 144.64021631343 0.912768751409737 0.362800213442242 SP2 other 0.000122328138650644 1 2.22155011832751e-05 6.40293502455524 0.912768751409737 0.0273498623407767 126.659020158204 78.3936769587748 1.61567903269559 0.108223925529644 -673.112018372032 322.394906028484 -2.08784942251092 0.0384685894402993 PRR15L other 1 1 1 1.61567903269559 -2.08784942251092 2.51016294649949e-18 171.52630268717 20.4652853723829 8.38132963045013 2.78864035532803e-14 -26.9416499518705 41.9954924161347 -0.641536707913907 0.522109527135845 COQ7 other 3.51146694585814e-14 1 3.85892052370293e-10 8.38132963045013 -0.641536707913907 8.46828294769099e-07 632.473052878356 225.043325147977 2.81045017648257 0.00557755429135755 -1891.40885292098 615.31751956039 -3.07387453273276 0.00249226360303555 GPRC5B other 0.00777219008939079 1 1 2.81045017648257 -3.07387453273276 2.15979660304317e-17 514.021232306411 54.4741198167027 9.43606310732538 1.04274040906624e-16 -340.906255656523 231.034353842378 -1.47556521351411 0.1422745827494 CRK other 2.99283015283691e-13 1 1.47161953931519e-12 9.43606310732538 -1.47556521351411 3.61415333186799e-07 145.726941609053 34.3430304631292 4.24327555384215 3.82852294966253e-05 -98.3112628000262 58.868696750374 -1.670009159824 0.096989225811481 FBXO22 other 0.00342441028194492 1 0.366236505364718 4.24327555384215 -1.670009159824 0.0586952870716232 115.351671295405 50.0544829396849 2.30452228293723 0.0225294736394645 26.5800819673607 89.4959892296555 0.296997465430027 0.766868655843217 TBC1D2B other 1 1 1 2.30452228293723 0.296997465430027 0.911849426994523 -2.13859317088558 16.3435274132941 -0.130852607078323 0.896068412296992 -9.38451226243989 24.2419418479208 -0.387118834015551 0.699220601267089 NOD2 other 1 1 1 -0.130852607078323 -0.387118834015551 0.24051879981836 -17.3589622269536 17.3846839979188 -0.998520434943294 0.31964589937524 7.95402570775194 25.7862631404296 0.30845980530157 0.758163313601894 SNX20 other 1 1 1 -0.998520434943294 0.30845980530157 1.31161376695209e-06 30.1486283784406 14.5294751280681 2.07499776232104 0.039753868530536 -66.0329078745158 29.5042428549545 -2.23808176332941 0.0267398372748523 KATNAL2 other 0.0118373142467426 1 1 2.07499776232104 -2.23808176332941 1.08278969545707e-14 77.0240671569115 20.152945643752 3.82197563167601 0.000193956041877718 -130.645039192178 40.6851938168715 -3.21111999073239 0.00161994541798838 HDHD2 other 1.44303382713564e-10 1 1 3.82197563167601 -3.21111999073239 0.00023556232394337 118.718256301698 36.2703151704921 3.27315204578872 0.00132209451371239 -74.2401026217324 102.625931752245 -0.723404907065395 0.470565279928374 ZNF91 other 1 1 1 3.27315204578872 -0.723404907065395 0.00535719837771041 51615.9343081355 18341.5077107563 2.81415983473734 0.00554231727264197 95896.1132671202 31462.7872647166 3.04792173879208 0.0027211338768358 IGF2 other 1 1 1 2.81415983473734 3.04792173879208 8.44921653812302e-17 155.473239012243 19.7743962710143 7.8623507328079 6.4574752687325e-13 -129.113009545838 54.3861754537388 -2.374004210972 0.0188453884166986 RNF214 other 1.1636261016303e-12 1 8.79508131601366e-09 7.8623507328079 -2.374004210972 1.69743066763931e-11 256.643912095822 33.5353856896855 7.65292859520499 2.10636658081263e-12 238.244883920894 202.904625808142 1.17417177145172 0.242162594686807 CDK12 other 2.07001669918614e-07 1 2.8452799773617e-08 7.65292859520499 1.17417177145172 0.372494836020058 -3.79104477611939 4.04798892026588 -0.936525482354923 0.350538741280277 -9.08597014925372 6.45244862744921 -1.40814296616037 0.161200105186153 DPEP2 other 1 1 1 -0.936525482354923 -1.40814296616037 6.39919261324502e-11 61.8003731343282 16.204435850773 3.81379356266698 0.000200871374788052 -48.1235820895523 25.8296877593829 -1.86311125933262 0.0644419521254569 DUS2 other 7.63929431473404e-07 1 1 3.81379356266698 -1.86311125933262 1.55084641121827e-07 82.5634665692085 30.8461404758421 2.67662227090842 0.00823181423955221 -191.299623631094 61.8697597023509 -3.09197295336877 0.00235591892708696 POP5 essential 0.00151920914442941 1 1 2.67662227090842 -3.09197295336877 0.72208313801114 21.7417183158795 27.3807700554309 0.794050652040265 0.428356925429988 -16.1291230319874 116.503729235794 -0.13844297635609 0.890066623142381 ENGASE other 1 1 1 0.794050652040265 -0.13844297635609 0.0111514428675583 217.130805630635 272.077691733695 0.798047073418864 0.426072066039198 -1814.61329980793 753.977676176987 -2.40672019496499 0.0172805570267063 ATP5L other 1 1 1 0.798047073418864 -2.40672019496499 0.645078493072407 -0.0519779938466688 5.77028082281659 -0.00900787941570187 0.992824507820759 13.7942773321858 15.9905168922641 0.86265362308952 0.389669336773251 CD3D other 1 1 1 -0.00900787941570187 0.86265362308952 4.00427383826762e-05 490.530919353732 107.769135725141 4.55168278053934 1.05630793024509e-05 470.202849699491 467.446380631474 1.0058968668541 0.316003198397486 TBC1D16 other 0.308008743639546 1 0.107035682571735 4.55168278053934 1.0058968668541 2.43559709992248e-05 119.373502233174 24.9866729322978 4.77748688497347 4.30355737712237e-06 51.1555906360707 111.105135545767 0.460425077425861 0.645900880177296 TEPSIN other 0.19321591793685 1 0.045122799099128 4.77748688497347 0.460425077425861 1.21410662147775e-07 239.567859886705 103.543804547057 2.31368608614173 0.0220430466591865 -485.054992841536 208.90396981923 -2.32190414218201 0.0215836364470782 MYO5B other 0.00119929452069572 1 1 2.31368608614173 -2.32190414218201 0.00241831197160149 14.3392436248209 5.23214601873465 2.74060463402141 0.00686273721807492 0.591322294472283 8.20800106480916 0.072042180526451 0.94266242855863 ART5 other 1 1 1 2.74060463402141 0.072042180526451 6.83175294560593e-10 353.095734401489 69.9426723193648 5.04835921609088 1.29098132884514e-06 -2.00424715172893 141.080836614687 -0.0142063741598218 0.988684467314961 ACAA2 other 7.77453485209955e-06 1 0.0140071474179697 5.04835921609088 -0.0142063741598218 0.00235496327922888 58.8546988913205 95.3930109254779 0.616970764632835 0.538177068347101 -340.093748110892 147.989584697883 -2.29809245566291 0.0229200865155861 RRM1 essential 1 1 1 0.616970764632835 -2.29809245566291 4.95871980661959e-08 24.7756750952188 19.7408186576139 1.25504800611007 0.211338201534748 -119.879645060176 30.8921362559192 -3.88058773491931 0.000153391766043911 TRIM68 other 0.000504351391531278 1 1 1.25504800611007 -3.88058773491931 0.0102187529295494 156.333920145452 50.9116913429401 3.0706880094081 0.00260871706257058 -9.98603194759025 244.180744176526 -0.0408960664825029 0.967442474713569 FN3K other 1 1 1 3.0706880094081 -0.0408960664825029 0.11936679310102 28.6516454488329 23.9978452144021 1.19392575428555 0.234379266734201 -50.1915830753834 51.2950415046279 -0.978488009817772 0.329398081514239 PRRT2 other 1 1 1 1.19392575428555 -0.978488009817772 5.4143201736897e-11 53.3759376631122 10.4430747327402 5.11113240392435 9.37087881206681e-07 -5.85650585340381 16.624836604828 -0.352274491028864 0.725114037506129 ZNF23 other 6.48094124790658e-07 1 0.0102564268598071 5.11113240392435 -0.352274491028864 4.77471578095959e-18 219.712810522141 25.2229914311193 8.71081493732206 4.43033978533047e-15 -38.6521745673774 71.7259358851995 -0.538887002175084 0.590742982634092 IRGQ other 6.65834115654815e-14 1 6.18121006849308e-11 8.71081493732206 -0.538887002175084 5.11136267820484e-14 29.3086326318816 4.64305203970999 6.31236358783354 2.72055966539279e-09 -70.6136566930452 20.3239906842107 -3.47439918617477 0.000663002644392643 ZNF226 other 6.72450873944629e-10 1 3.38356005584901e-05 6.31236358783354 -3.47439918617477 1.62856922947726e-26 45.0638364181821 3.88944907567038 11.5861746847566 8.66360116292224e-23 -41.0583893340486 16.5520644506637 -2.48056002055999 0.0141793380877993 ZNF180 other 2.35230539505695e-22 1 1.24825165555384e-18 11.5861746847566 -2.48056002055999 0.000393129258188375 54.7980110070483 14.382576399498 3.81002745856862 0.000201740051657993 12.0223809983586 29.7832982261697 0.403661841178989 0.687032465093593 ZNF668 other 1 1 1 3.81002745856862 0.403661841178989 1.90502465399989e-07 225.607125615525 43.534908723216 5.18221198188053 6.92213945412271e-07 -15.9779150976797 90.151662243065 -0.177233727034343 0.859562319050401 ZNF646 other 0.0018532079834111 1 0.00763927310156982 5.18221198188053 -0.177233727034343 0.0257251969731545 82.3073884418433 114.902833921477 0.716321657463134 0.474906504763361 -489.439990246282 238.064777964605 -2.05591097696548 0.0415246538732659 VKORC1 other 1 1 1 0.716321657463134 -2.05591097696548 0.625018476170928 10.8469553172543 12.443897399818 0.871668655626566 0.384728694720747 -19.07219562686 47.1000430665192 -0.404929473205034 0.686084068130031 LPO other 1 1 1 0.871668655626566 -0.404929473205034 0.840519908038558 -2.62361360551679 11.4718181406061 -0.228700766814821 0.81940296089004 24.8685855691587 45.8980261318951 0.541822550226778 0.588718781717487 CA4 other 1 1 1 -0.228700766814821 0.541822550226778 8.26192100472835e-11 140.235273494847 19.2626889375432 7.28015044781869 1.53843456348051e-11 86.6081014951102 74.4103123788856 1.16392605710503 0.246231023317653 SMG8 other 9.81516215361728e-07 1 2.04365647412752e-07 7.28015044781869 1.16392605710503 2.62714676568309e-11 3913.24695696484 582.497657670951 6.71804754136094 3.41132910061947e-10 -5479.27229080296 3551.08103449609 -1.54298711788775 0.124899698841904 TPM4 other 3.1825255919485e-07 1 4.36616011588286e-06 6.71804754136094 -1.54298711788775 1.17277237365869e-22 551.469789411349 49.920793475756 11.0468955121711 3.3845982067332e-21 -278.616504673001 304.719492048801 -0.914337651325505 0.361987591084621 RAB8A other 1.6771817715693e-18 1 4.86028302486888e-17 11.0468955121711 -0.914337651325505 0.0114138832867183 437.044009987278 592.655394591022 0.737433614839315 0.462101715035266 -2017.60325999906 884.523292355057 -2.28100636516553 0.0240684777414389 GPX4 other 1 1 1 0.737433614839315 -2.28100636516553 0.0236986630800895 499.030884265281 226.761067870016 2.20069030787655 0.0294086243193524 -170.064680065784 340.234220350458 -0.499845899952711 0.617973935865035 MIDN other 1 1 1 2.20069030787655 -0.499845899952711 1.02199132003034e-20 150.898415567036 16.068854232735 9.39073896504894 9.16908951018494e-17 -70.6900250391456 51.2493603054751 -1.37933477838149 0.169844549946337 KLHL26 other 1.44969468746303e-16 1 1.29476712973322e-12 9.39073896504894 -1.37933477838149 1.06068833051426e-17 711.02820234691 76.9554629706491 9.23947663882025 2.26104923603259e-16 112.078296026033 250.384811496253 0.447624180381684 0.655070217137944 GATAD2A other 1.47446284824787e-13 1 3.1840095341811e-12 9.23947663882025 0.447624180381684 5.46379146347655e-09 189.578525473995 33.4065250962605 5.67489509692274 7.37091670996789e-08 48.8409497910722 59.5008675494979 0.820844330554376 0.413091749496714 MVD essential 5.91609878638861e-05 1 0.000862028709230744 5.67489509692274 0.820844330554376 0.0239242055985164 215.667587776333 96.3075203920706 2.23936393438793 0.0266867827268342 14.0566888816648 169.401686652521 0.0829784470239548 0.93398553417694 CDT1 essential 1 1 1 2.23936393438793 0.0829784470239548 0.0510371294408903 101.314911706998 56.7550502846401 1.78512592621942 0.0763756601740814 -26.8238772618269 98.9414170320566 -0.271108682960707 0.786701147169697 TRAPPC2L other 1 1 1 1.78512592621942 -0.271108682960707 1.78058115347242e-16 1629.4224 185.175319797822 8.79934972856556 4.05698233473867e-15 656.928520000001 320.922327953648 2.04700160374907 0.0424890155706537 ANKRD11 essential 2.44171093575673e-12 1 5.66273594282824e-11 8.79934972856556 2.04700160374907 1.66553712339822e-06 114.285935803424 28.6879530618874 3.98376055471367 0.000109682944114599 -25.4741228004938 50.6683462303116 -0.50276207328145 0.615938815808808 SPATA33 other 0.0148948984945503 1 0.998005108498735 3.98376055471367 -0.50276207328145 0.00229188662603279 26.187567584268 7.37842334775921 3.54920913994736 0.000531061867329845 6.25714462260953 29.698771465627 0.21068698514521 0.833446876243956 PROCA1 other 1 1 1 3.54920913994736 0.21068698514521 0.0280018240363106 8079.22995202192 4142.18752977227 1.95047421053535 0.0531462781922486 -2367.92558295541 7308.55317483346 -0.323993754483337 0.746433290832923 RPL13 essential 1 1 1 1.95047421053535 -0.323993754483337 0.000223696345538048 88.881459730434 31.2556402839806 2.84369345573727 0.00508623763936169 -158.132364676887 85.1447481345011 -1.85721806854239 0.0652541996534458 ZNF641 other 1 1 1 2.84369345573727 -1.85721806854239 3.83246253343735e-06 212.490949217117 43.9761921098736 4.83195426939678 3.42303406999653e-06 -4.57303349904763 119.740144637607 -0.0381913143072268 0.96958804139388 CACNB3 other 0.0330089998004959 1 0.0361095864043934 4.83195426939678 -0.0381913143072268 5.21669114641788e-06 121.784460431654 23.7017858822207 5.13819764623762 9.50649358379086e-07 31.671223021582 102.804378964204 0.308072704107377 0.758501833859362 DHRS13 other 0.0442897078330878 1 0.0104010546300256 5.13819764623762 0.308072704107377 1.96132448748388e-07 136.720843406678 28.7384959115155 4.75741123779181 4.88209507892585e-06 -305.299109465371 115.435524433568 -2.64475871672475 0.0091225554901207 TP53I13 other 0.00190640740183433 1 0.0509202516731966 4.75741123779181 -2.64475871672475 2.09630141462146e-05 610.864352318548 161.655571465384 3.77880172505748 0.000232407591286999 -604.223436530707 440.094381005767 -1.37294058413072 0.171965928097242 KMT2D other 0.167431593985816 1 1 3.77880172505748 -1.37294058413072 0.501142738888485 -0.546449465402466 2.37018092448297 -0.230551794488713 0.818002000869222 -11.2336493847085 9.53823619828217 -1.17774913004689 0.240909166530545 CORO6 other 1 1 1 -0.230551794488713 -1.17774913004689 0.322811531052839 -0.982862836267021 2.10573420906374 -0.466755411027883 0.641390213789049 -8.63615315272571 5.73301795596186 -1.50638864539833 0.13418878347673 RHEBL1 other 1 1 1 -0.466755411027883 -1.50638864539833 0.013767222145022 907.250351864884 583.987802244253 1.55354332466935 0.122443708377929 -2778.44747439205 1577.25252436262 -1.76157427645572 0.0802201784130459 TUBA1A other 1 1 1 1.55354332466935 -1.76157427645572 0.0225863786443762 785.863828289934 628.933426385575 1.24951830403772 0.213461392326821 -3125.91074360779 1698.64307201365 -1.84023989212883 0.0677496543090636 TUBA1C essential 1 1 1 1.24951830403772 -1.84023989212883 0.00667484335959995 29.1299686479138 12.614783694228 2.30919287670723 0.0222620620298505 -13.3093568859065 24.573063714939 -0.541623830072732 0.588860412334248 ZNF610 other 1 1 1 2.30919287670723 -0.541623830072732 0.00802119682463218 68.3408169082018 26.7850808292106 2.55145083727627 0.0117019932815454 -4.63333575065412 52.1762016519668 -0.0888017066010299 0.929354879168315 ZNF528 other 1 1 1 2.55145083727627 -0.0888017066010299 1.34305529069075e-11 45.329689444807 8.74284645115004 5.18477474105064 6.70509190079673e-07 -61.4931937463592 24.3765752627462 -2.52263466395695 0.0126631400891313 ZNF701 other 1.64309384263106e-07 1 0.00740510349523991 5.18477474105064 -2.52263466395695 3.36453804915076e-11 72.089792706994 16.220475361415 4.44436991522948 1.68351109603959e-05 -176.777735624795 54.4264594658983 -3.24801093731914 0.00142847235883855 SERTAD3 other 4.0572964334709e-07 1 0.167223157169613 4.44436991522948 -3.24801093731914 6.02528652824299e-09 289.479997719888 56.3765686255953 5.13475730746164 8.64296617048047e-07 -249.216745140512 143.517641830543 -1.73648857354257 0.0845305744136606 NCKAP5L other 6.5082197058478e-05 1 0.00948046959240003 5.13475730746164 -1.73648857354257 4.71182162390482e-24 216.322585616378 24.5949918889362 8.79539162253959 2.4045403916093e-15 -286.807790695124 81.3355801780806 -3.52622788289173 0.000552778427274265 RAB4B other 6.76806058057689e-20 1 3.3627497376656e-11 8.79539162253959 -3.52622788289173 0.0313695809216261 -4.45816884384839 2.83138558955531 -1.57455376628818 0.117438603399743 -18.6833401474988 7.20958261767626 -2.59145933104248 0.0104882249103264 AQP2 other 1 1 1 -1.57455376628818 -2.59145933104248 0.883132158071433 -4.14067048549161 18.3662977224616 -0.225449382780485 0.821928603968742 15.0896863336878 46.7771646055435 0.322586596706624 0.747445885220358 GPD1 other 1 1 1 -0.225449382780485 0.322586596706624 2.37857366535966e-24 215.538145366696 19.2992770144246 11.1681979177561 1.37664428774595e-21 -75.6760382164212 83.3517149515771 -0.90791219185334 0.36534317233109 PROSER3 other 3.41896178658797e-20 1 1.97851317034848e-17 11.1681979177561 -0.90791219185334 0.00403735015797481 66.3018275271277 66.9561243140674 0.990227976997733 0.323586365546811 -414.690029939602 184.404365403051 -2.2488080964527 0.0259160167845547 CYP2S1 other 1 1 1 0.990227976997733 -2.2488080964527 0.0510144614575211 111.809394631639 52.769189046091 2.1188385998121 0.0356776826308258 3.74069362961436 145.332020312794 0.0257389501746647 0.979498242724684 AXL other 1 1 1 2.1188385998121 0.0257389501746647 8.07921894431017e-10 49.9769417139448 10.9001988686856 4.58495687244017 9.33761518089343e-06 -145.331050243264 47.8737371338161 -3.03571559155777 0.00281834391346737 NFKBID other 9.16506597042545e-06 1 0.0950475849263143 4.58495687244017 -3.03571559155777 0.000816530755548342 184.496997463222 193.600036720087 0.952980178046008 0.342074379205234 -1027.92204535735 399.79573310794 -2.57111809915145 0.0110717092125296 TMC4 other 1 1 1 0.952980178046008 -2.57111809915145 0.155094430350174 69.4006152794392 41.8226723318057 1.65940174097055 0.0990311057886077 156.888224235173 89.3077689676611 1.75671418118152 0.0809160836115745 LAIR1 other 1 1 1 1.65940174097055 1.75671418118152 0.232726492094712 108.914517459811 238.503660710233 0.456657634249628 0.648548297444548 -570.603841956775 509.964211800898 -1.1189095798345 0.264887712162226 TTYH1 other 1 1 1 0.456657634249628 -1.1189095798345 0.00203242615717126 657.638294474607 341.604721910468 1.9251440401546 0.0560191783751098 -1055.91098690514 730.413035329409 -1.44563546354145 0.150272657471417 LENG8 essential 1 1 1 1.9251440401546 -1.44563546354145 0.173213285447574 58.7080738315768 53.3386203479145 1.10066727351849 0.272726182977094 -74.7849582135629 114.047672908966 -0.655734188221948 0.512954938279309 CDC42EP5 other 1 1 1 1.10066727351849 -0.655734188221948 8.92402779972087e-24 90.7981460003116 12.1801244912884 7.45461559651982 6.23170172297001e-12 -145.912614468468 32.2496379580861 -4.52447294627325 1.20809551492997e-05 ZNF526 other 1.28077646981594e-19 0.175306740171489 8.34549494740143e-08 7.45461559651982 -4.52447294627325 1.03666834519564e-05 226.389255532631 46.7769485186186 4.83976109391833 3.23435946327694e-06 -0.929799892597322 248.1551846874 -0.00374684854466606 0.997015500043749 TRAPPC9 other 0.0855666052124478 1 0.0341774764484474 4.83976109391833 -0.00374684854466606 0.0522848774391069 128.509028784133 80.2451180676689 1.60145603718552 0.111286128487867 -104.428207313954 167.310714738691 -0.624157319972315 0.53343016227583 NLRP7 other 1 1 1 1.60145603718552 -0.624157319972315 1.36710562948246e-21 531.818871330118 58.4451971616825 9.09944524370236 4.97874463117959e-16 -703.322593176438 242.432866618054 -2.90110249071346 0.00427475838801336 ZNF146 other 1.94798881144955e-17 1 6.99662983019668e-12 9.09944524370236 -2.90110249071346 3.24403293924169e-16 18.1839509428195 3.10307253374218 5.85998256408478 2.63679110189688e-08 -32.81718469555 8.65136871793299 -3.79329395908476 0.000211736995886888 ZNF283 other 4.43361981806161e-12 1 0.000315175640409735 5.85998256408478 -3.79329395908476 1.56608456349685e-06 198.272013985421 41.476126562665 4.78038887469055 4.09462733869272e-06 -40.826304551063 158.550363261681 -0.257497388912827 0.797143099500425 PPP1R14A other 0.0140462124500032 1 0.0429731139195801 4.78038887469055 -0.257497388912827 1.99578702310695e-21 4029.59870454124 451.6637816329 8.92167773553381 1.37245559943143e-15 -4841.85251717498 1726.57050175226 -2.80431787306749 0.00570107372577765 SPINT2 other 2.8420007209043e-17 1 1.92253580368355e-11 8.92167773553381 -2.80431787306749 0.000695902258353897 615.75505208833 198.258109629766 3.10582529631808 0.00226433808566545 -626.673592811833 757.879240576651 -0.826877897242591 0.409602439029607 C19orf33 other 1 1 1 3.10582529631808 -0.826877897242591 2.44800971033012e-14 303.234129737762 40.8411539362385 7.42471993350564 7.52470889641428e-12 -177.880712256878 156.123059920588 -1.13936219510018 0.256344468621064 YIF1B other 3.24165445841915e-10 1 1.00567734400577e-07 7.42471993350564 -1.13936219510018 0.680124417301399 14.6616793211255 36.3314857896795 0.403552978978095 0.687101247563687 -30.4848146493971 71.6425660687159 -0.425512601267766 0.671057076453192 DNAAF3 other 1 1 1 0.403552978978095 -0.425512601267766 0.0503290709994628 85.0012739350293 37.3517943710898 2.27569452462022 0.0245131290107217 -38.6046771614647 161.371676023517 -0.239228333699891 0.811308199610536 PSCA other 1 1 1 2.27569452462022 -0.239228333699891 0.838330999480503 2.51121842786018 16.7268148535255 0.150131298149145 0.880895512743911 -36.355473370858 72.2651801043773 -0.503084242208315 0.615762932253455 LY6D other 1 1 1 0.150131298149145 -0.503084242208315 5.13657732120576e-06 15702.2317904557 4567.63600046401 3.43771521830123 0.000758207494726769 -9341.2011861795 6829.89925143731 -1.36769238348775 0.173440504875792 EEF2 essential 0.0436454974982854 1 1 3.43771521830123 -1.36769238348775 0.000224638970471956 74.1812749584634 35.7534340951403 2.07480139561045 0.0396686294425105 -89.8371177893723 55.2795534736277 -1.62514188600006 0.106177149448745 CHAF1A essential 1 1 1 2.07480139561045 -1.62514188600006 7.37239673583329e-09 464.17861115825 130.791244547201 3.54900370254321 0.000512105578049422 -425.669136640456 203.49966340671 -2.09174368897959 0.0380919647343348 UBXN6 other 7.91869133395854e-05 1 1 3.54900370254321 -2.09174368897959 0.147062629046716 79.3969995789103 44.5081474272555 1.78387563105558 0.076400414834878 30.9072502843921 69.2507594958624 0.446309188655739 0.655996797159104 PLIN4 other 1 1 1 1.78387563105558 0.446309188655739 0.179957430033955 -21.5934786394962 14.6650117020321 -1.47244878341993 0.142927368998327 -41.1152372421683 22.8003977825809 -1.8032684181317 0.0732883899778526 SEMA6B other 1 1 1 -1.47244878341993 -1.8032684181317 5.89893518033329e-16 269.381243660284 49.0264741575067 5.4946077255086 1.56138649845719e-07 -331.522146743306 99.4390221374349 -3.33392404327054 0.00106975164831992 ZNF444 other 8.03670928968607e-12 1 0.00179575061187562 5.4946077255086 -3.33392404327054 3.42907125618814e-08 838.328297554583 136.319981901841 6.14970957198507 8.10852594988675e-09 169.722886547672 560.628582277517 0.302736770676557 0.762553020247418 NXN other 0.000352920013686884 1 9.90456444778667e-05 6.14970957198507 0.302736770676557 5.83420624638751e-06 180.687919283567 40.1608761460714 4.49910302321035 1.46537996868832e-05 -217.99087339376 162.595555440467 -1.34069392489376 0.182288269068579 FAM57A other 0.0492698717507425 1 0.146288882274155 4.49910302321035 -1.34069392489376 2.91891318954211e-19 378.861827675123 38.1383830039231 9.93387233108839 9.17366118910246e-18 -316.884810031779 154.407278007821 -2.05226602087842 0.0420906592211258 GLOD4 other 4.1066189663668e-15 1 1.30174252273364e-13 9.93387233108839 -2.05226602087842 0.10621681078047 157.704512950898 75.4321647785313 2.0906799296284 0.0389941624295371 55.23824090259 279.236677877525 0.197818715372405 0.843573042253961 MFSD3 other 1 1 1 2.0906799296284 0.197818715372405 0.770365447340395 -36.4992721979621 51.7309902147003 -0.705559125129413 0.482039738147173 -11.958806404658 199.790076908552 -0.0598568587074113 0.952384509868287 GPT other 1 1 1 -0.705559125129413 -0.0598568587074113 0.0198326380998687 277.46208684381 113.760486684837 2.43900228391686 0.0164047319724335 -299.476128753511 439.098347885153 -0.682025177721324 0.496724768479487 KIFC2 other 1 1 1 2.43900228391686 -0.682025177721324 2.95994666422695e-05 273.870492382517 58.1292651188543 4.71140469129527 5.76949663466015e-06 143.363041173908 265.845131245843 0.539272773219727 0.590537294553614 SLC43A2 other 0.232237415275246 1 0.0598239106047911 4.71140469129527 0.539272773219727 0.204768695500221 24.9468127117411 14.9405582831547 1.66973765229833 0.0971589000862641 68.1681146467698 68.3283139663013 0.997655447497059 0.320131645085842 RILP other 1 1 1 1.66973765229833 0.997655447497059 0.0177536252566663 18.7378001930692 7.29084788832329 2.57004404427075 0.0111494530282155 -23.5869993498691 33.5006437255453 -0.704076003527156 0.482484354224497 SERPINF2 other 1 1 1 2.57004404427075 -0.704076003527156 4.47511200570793e-07 218.135838150289 40.6873926741382 5.36126362033861 3.13443671695487e-07 -127.628050738602 186.555791384627 -0.684128055158938 0.494971394542993 WDR81 other 0.00421108039737116 1 0.00353595806039678 5.36126362033861 -0.684128055158938 2.30526797153214e-19 225.975907904107 22.6962173585665 9.95654493143164 3.04497153844109e-18 -184.405372260464 103.793532172128 -1.77665571641451 0.0776518778570054 SRR other 3.24535625032295e-15 1 4.33208100774014e-14 9.95654493143164 -1.77665571641451 2.20165045532427e-22 537.80447424638 47.8953656052485 11.2287372160167 1.28443646061561e-21 -297.405668961154 219.033378659807 -1.3578098040622 0.176563096009843 TSR1 essential 3.14439718029412e-18 1 1.84612052484282e-17 11.2287372160167 -1.3578098040622 9.21409539036339e-10 16.9931932524416 2.82620057431014 6.01273434267471 1.24602210939963e-08 -36.8823123211996 15.8650280434167 -2.3247555705711 0.0213741367630303 TRPV3 other 1.0420220476962e-05 1 0.000151055260322517 6.01273434267471 -2.3247555705711 1.78165019606683e-08 76.9143204342431 15.9404056683221 4.82511687811639 3.32078909535856e-06 2.78215433712868 28.7896793399754 0.0966372116991788 0.923139342004478 HSD11B1L other 0.000187197986100741 1 0.0350708536360818 4.82511687811639 0.0966372116991788 1.46012730716799e-07 90.2041943526548 16.5541485663146 5.44903858940881 1.92254941460659e-07 -129.070222004843 93.9968724565167 -1.37313315466482 0.171668872959837 CYB5D2 other 0.00143355299017753 1 0.00219728172595387 5.44903858940881 -1.37313315466482 1.6346087642263e-07 233.667635518093 52.5087412079178 4.45007117182345 1.62552972363084e-05 -913.807392336387 297.014072225851 -3.07664679147432 0.00247305140052019 GGT6 other 0.00159864737141332 1 0.16164267571785 4.45007117182345 -3.07664679147432 9.58800999836988e-11 567.445407233191 113.338687870414 5.00663469725341 1.49012871639185e-06 -283.650960708997 204.23450419055 -1.38884936134177 0.166870915959084 C19orf48 other 1.13608330470685e-06 1 0.0161023309093303 5.00663469725341 -1.38884936134177 0.503646202079817 29.2322201695991 41.016593733794 0.712692535107185 0.477107545897214 -24.8063017790004 73.9112463908569 -0.335622831305264 0.73760915242808 KLK1 other 1 1 1 0.712692535107185 -0.335622831305264 0.099324146057093 67.4657150837318 718.426603792591 0.0939075957482347 0.925303840744841 -2248.15016622638 1319.64390186431 -1.70360364871942 0.0904592216493671 KLK5 other 1 1 1 0.0939075957482347 -1.70360364871942 0.130946718801869 1723.77838746844 867.662350345852 1.9866926192906 0.0487190938255447 2382.88033253033 1593.76799726883 1.49512371726234 0.136915332930092 KLK6 other 1 1 1 1.9866926192906 1.49512371726234 0.462094192889681 9.98848749504055 377.719916250802 0.0264441642214288 0.978936651011 -706.524176260417 705.855926256325 -1.00094672294902 0.318392778851376 KLK11 other 1 1 1 0.0264441642214288 -1.00094672294902 0.090605982247728 -5.2625861633402 38.4279528990651 -0.136946825587169 0.891248285267648 -134.842340033923 71.8114060728892 -1.87772872594999 0.062272969835157 KLK13 other 1 1 1 -0.136946825587169 -1.87772872594999 0.0020312406582109 89.8519213335473 48.814815285584 1.8406690839222 0.0675821490293768 -248.740188742809 135.916810585966 -1.83009141893808 0.0691572706685088 ZNF83 other 1 1 1 1.8406690839222 -1.83009141893808 0.06651452427302 140.995774994505 99.9217506418204 1.41106189682283 0.160243353325316 -351.267080838689 277.871112226974 -1.26413673599781 0.208090964883138 KRT80 other 1 1 1 1.41106189682283 -1.26413673599781 0.0752103341202083 -7.68709129866154 5.07729158190123 -1.51401414999748 0.132085301068264 15.5259342738681 14.3256459043929 1.08378598615977 0.280164627645354 KRT1 other 1 1 1 -1.51401414999748 1.08378598615977 0.000164872495702069 588.48360198872 188.193328933909 3.12701627269363 0.00213170377852128 -1309.25837736606 625.47159641642 -2.09323394518206 0.0380576651964603 OTUB1 other 1 1 1 3.12701627269363 -2.09323394518206 0.000148135391786769 277.969633363465 64.726377781354 4.29453405074585 3.18886785307506e-05 109.803022874565 212.676899613598 0.516290312084015 0.606438119198595 RCOR2 other 1 1 0.308235966678235 4.29453405074585 0.516290312084015 0.174654636335253 61.4973124763124 48.8200871210627 1.25967232143222 0.209718339107709 -93.5641330439066 162.587954771393 -0.575467802491656 0.565825901943416 ANGPTL4 other 1 1 1 1.25967232143222 -0.575467802491656 0.000217610970697322 217.549706071113 77.0605413513549 2.82310119103891 0.00538484240319284 -331.611571527895 255.398324148412 -1.29840934796109 0.196087733751348 NDUFA7 other 1 1 1 2.82310119103891 -1.29840934796109 1.97553740866447e-12 336.937715175048 49.5460888132617 6.8004906793947 2.16499439900954e-10 -46.8129097168728 162.609909323773 -0.287884729236664 0.773822040219603 CD320 other 2.48562116758164e-08 1 2.7911107792031e-06 6.8004906793947 -0.287884729236664 0.000315703588672302 99.6010226442659 44.1649699488836 2.25520413032192 0.0256607658906049 -278.718553688825 111.580903474284 -2.4979055108033 0.0136420472099228 SPRYD3 other 1 1 1 2.25520413032192 -2.4979055108033 0.264718977448514 80.8120231919439 62.5973961413379 1.29098058662823 0.19883810766523 -84.2383903351252 161.57795649311 -0.521348283908499 0.602947903564932 IGFBP6 other 1 1 1 1.29098058662823 -0.521348283908499 1.99074489707727e-29 231.054109623593 18.0740471955607 12.7837504861857 8.88978099061061e-26 -3.59834505263987 61.913367748105 -0.0581190328279308 0.953731166149178 ZNF558 other 2.88359398341642e-25 1 1.28519563781258e-21 12.7837504861857 -0.0581190328279308 0.0690577985746471 293.637787498236 166.505261579565 1.7635345857099 0.0798196032630159 -657.667856638917 546.212873302463 -1.20405045136081 0.230441727476421 NDUFV1 other 1 1 1 1.7635345857099 -1.20405045136081 0.14481617225748 337.071281900848 202.605347864841 1.66368403131052 0.0982634171292588 -506.854326782049 656.756799966961 -0.771753450908383 0.441474595493236 CDK2AP2 other 1 1 1 1.66368403131052 -0.771753450908383 0.750589632386616 1.1032877098914 24.9071052223834 0.0442961034628746 0.964726516479102 -60.3250599689572 81.7066162360511 -0.73831303691096 0.461462662079129 NUDT8 other 1 1 1 0.0442961034628746 -0.73831303691096 1.44839479376667e-05 1029.26167283047 285.011365779475 3.61130044767004 0.000416493098370029 -2396.46378931491 1426.82698655769 -1.67957559808743 0.0951497164415658 PRDX2 other 0.117595173305916 1 1 3.61130044767004 -1.67957559808743 7.48162965182531e-18 103.96449704142 10.2840919593389 10.1092539285406 8.11824216976216e-19 69.7328825021135 55.6289912451756 1.25353490942838 0.211874574821236 ZNF232 other 1.04129321494105e-13 1 1.15758015098639e-14 10.1092539285406 1.25353490942838 1.69336783695974e-17 194.250449910018 21.8253761357368 8.90021086930787 1.2851695372731e-15 -333.850220864917 116.307485533306 -2.87041044120341 0.00466505678595939 MIS12 essential 2.34920920021424e-13 1 1.80065103867334e-11 8.90021086930787 -2.87041044120341 0.405652990614133 -3.93824701195218 2.92328241456036 -1.3472003226019 0.17988191190151 -0.321912350597587 11.884020926329 -0.027087831012178 0.978424524681665 CD300C other 1 1 1 -1.3472003226019 -0.027087831012178 0.0421989218384112 -16.8597609561753 10.8602767629326 -1.55242461349785 0.122600103909119 88.0203452855247 44.1502865660776 1.99365286460347 0.0479444203718126 CD300A other 1 1 1 -1.55242461349785 1.99365286460347 0.474184258003994 -14.8003195559854 22.4528634459797 -0.659172919819075 0.510762844802819 -140.017085032726 120.539200496338 -1.16158962774089 0.247187823575101 TEKT1 other 1 1 1 -0.659172919819075 -1.16158962774089 0.0187752763571395 728.554647395964 255.069788833937 2.85629533284433 0.00488231413359163 99.7570707700173 1078.1760644992 0.0925239152070711 0.926402830270126 HID1 other 1 1 1 2.85629533284433 0.0925239152070711 9.29717069638325e-09 160.858554067403 28.4325041872614 5.6575584411405 7.15496395410274e-08 -379.147051391027 123.847986782384 -3.06139050978062 0.00259497237005641 MRPL58 other 9.93402688908551e-05 1 0.000837345431548644 5.6575584411405 -3.06139050978062 2.81405760979308e-05 639.954811734705 136.29793641355 4.69526412926003 5.79327121683547e-06 -339.235463713848 593.69462908492 -0.571397225264985 0.568552724430837 ATP5H other 0.221607036771205 1 0.0600588427049333 4.69526412926003 -0.571397225264985 0.13300696499088 22.6848632063411 11.9533334832321 1.897785520513 0.0597684514511455 -9.29202250063926 60.0138225717085 -0.154831372214902 0.877175673306437 TMEM88 other 1 1 1 1.897785520513 -0.154831372214902 0.000170420466081133 441.169702583102 105.699039595611 4.173828866099 4.96192305012702e-05 447.936824637236 493.968893272501 0.906811806852235 0.365904891830362 EVPL other 1 1 0.46954677823352 4.173828866099 0.906811806852235 1.68045087023051e-11 433.440700295126 57.1797106566492 7.58032342796969 2.87944052106396e-12 234.26819030152 266.67994060749 0.878461986184124 0.381044081136128 SRP68 other 2.04981397150717e-07 1 3.88090993429001e-08 7.58032342796969 0.878461986184124 0.18815474486853 68.4937878410882 37.9410360942409 1.80526930447967 0.0729364743725653 68.2616737165135 167.37452445452 0.407837894918484 0.683944790447042 MGAT5B other 1 1 1 1.80526930447967 0.407837894918484 0.0609203792332424 -23.3769224328021 21.026161475525 -1.11180171711387 0.26791228594353 172.397926145086 82.5309990150763 2.08888694190644 0.0383210532478424 TMC8 other 1 1 1 -1.11180171711387 2.08888694190644 0.0157342698734214 414.656139224607 143.056137847052 2.89855538857015 0.00428217744835387 231.117076506544 561.517896906616 0.411593428775397 0.68119524257295 TK1 other 1 1 1 2.89855538857015 0.411593428775397 0.000128180159600576 57.4899975688533 18.9773857977782 3.02939499578408 0.00287455041255894 -196.413468551385 78.250149535866 -2.51007147866674 0.0131038287459547 TMEM99 other 0.926486193592963 1 1 3.02939499578408 -2.51007147866674 1.14923717838737e-06 95.8320137570306 27.5556974104574 3.4777567894421 0.000655348179006786 -417.715813420271 109.807636416605 -3.80406888857417 0.00020391899861205 GHDC other 0.0104324437291355 1 1 3.4777567894421 -3.80406888857417 3.23891116319074e-10 689.380525731395 125.441406932981 5.49563770517742 1.97775207249304e-07 -211.372094003113 274.831185923248 -0.769097922031831 0.443230262469965 FAM234A other 3.74839188916065e-06 1 0.0022583950915798 5.49563770517742 -0.769097922031831 0.162604235425836 23.2549778239124 12.2875887092824 1.89255828577213 0.060269020397872 25.761085422499 52.3804691661906 0.491807076808826 0.623547047615687 SOST other 1 1 1 1.89255828577213 0.491807076808826 4.33782710681158e-11 520.794848293903 78.2997291330633 6.6512982108643 6.26199006885823e-10 96.277399069459 165.215908907148 0.582736854497271 0.561021443174485 ZNF598 other 5.20929657257002e-07 1 7.95648458149127e-06 6.6512982108643 0.582736854497271 0.00633374539798369 -0.316281911745058 8.60462956816869 -0.0367571792881227 0.970731734563529 -49.8884178903082 18.1561508660955 -2.74774197781475 0.00680276673288456 RAB26 other 1 1 1 -0.0367571792881227 -2.74774197781475 5.46936872641809e-10 449.603941513033 83.5782967451699 5.37943412371605 3.11406110879552e-07 -164.137296037297 176.931157788859 -0.927690171073035 0.355188002500499 MLST8 essential 6.25859863364022e-06 1 0.00351359514905399 5.37943412371605 -0.927690171073035 2.29394735195202e-10 125.469866497139 29.6323657234868 4.23421699326866 4.16297378945572e-05 -164.683682983683 62.7302658663285 -2.6252667784735 0.00963467737021454 E4F1 essential 2.6724486650241e-06 1 0.396648142659341 4.23421699326866 -2.6252667784735 0.0839783107233069 1.93210425937699 3.14899627165342 0.613561939329485 0.540514857024977 -9.86829836829837 6.66627076542616 -1.48033266507552 0.141063912058804 DNASE1L2 other 1 1 1 0.613561939329485 -1.48033266507552 6.60885976248052e-05 179.875527135597 120.908394643038 1.48770089675451 0.139078689212479 -683.483423512051 252.111430635747 -2.71103702751009 0.00754728575867576 ECI1 other 0.495994925174163 1 1 1.48770089675451 -2.71103702751009 9.08006655593431e-17 337.629765282434 37.5399857374013 8.99387036649969 1.73365019300916e-15 110.871859685324 79.3717100752629 1.39686872791568 0.164711675092637 CASKIN1 other 1.24987116142436e-12 1 2.42676354017422e-11 8.99387036649969 1.39686872791568 2.82212690983364e-06 321.954946553399 74.2251282425577 4.33754651795675 2.71636839657611e-05 -25.1973135638384 159.237029053566 -0.158237777441591 0.874494245097501 ABCA3 other 0.0246287015421182 1 0.264384136038753 4.33754651795675 -0.158237777441591 7.06798615143797e-12 274.325231674528 37.989890746675 7.22100606984604 2.46137567234179e-11 92.0725830125362 81.4093787440874 1.13098250389515 0.259879568205508 KCTD5 other 8.73320368871676e-08 1 3.25763070234436e-07 7.22100606984604 1.13098250389515 2.73888642806641e-07 5434.94739187984 1167.43387425855 4.6554648719026 7.12765842829634e-06 -1349.45274048462 2505.93824272186 -0.538501993975276 0.591039527008822 SRRM2 essential 0.0026230315321592 1 0.0732580733260298 4.6554648719026 -0.538501993975276 0.000134239982269559 -3.11032629425434 10.1112845398826 -0.30760941223502 0.758795175416181 -79.2028156316101 20.8244711442406 -3.80335303994095 0.000205360991721827 ZNF597 other 0.96733331223444 1 1 -0.30760941223502 -3.80335303994095 0.0991560897174825 1.8815495824268 7.58594327063268 0.248031064206715 0.804442946829989 -26.0941820478631 15.6098953800339 -1.67164362172723 0.0966386083591344 NLRC3 other 1 1 1 0.248031064206715 -1.67164362172723 0.00575113914938255 40.3911756895177 45.313000256632 0.891381622509228 0.374152076986812 -405.99855077962 149.673507648313 -2.71256120845107 0.00745718909599837 SDHAF2 other 1 1 1 0.891381622509228 -2.71256120845107 1.2756811030087e-06 1299.62229055157 296.833182524338 4.37829180517919 2.23191489255177e-05 -1691.27630869681 980.847562629742 -1.72430087317783 0.0867136020056491 DDB1 essential 0.0115270544467866 1 0.218950850959328 4.37829180517919 -1.72430087317783 2.33233677296899e-06 113.102914931588 34.8737806638057 3.24320772737364 0.00145689501782998 -335.973587150506 112.909849741078 -2.97559148223961 0.00340962895973443 VPS37C other 0.0205525516434028 1 1 3.24320772737364 -2.97559148223961 0.261811862252071 62.8561173904423 62.77890891859 1.00122984730353 0.318328123575959 -187.143208407694 203.257491387035 -0.92071985701793 0.358675096782654 VWCE other 1 1 1 1.00122984730353 -0.92071985701793 0.85243638497286 -1.26097789332775 3.62263890330661 -0.34808268971461 0.728286407384228 -6.15762513831176 11.8939362096933 -0.51771129672727 0.605454144162231 HRASLS5 other 1 1 1 -0.34808268971461 -0.51771129672727 0.00860894390974438 158.987449045269 50.7805830708656 3.13087088471194 0.00210831331201138 103.246299077451 166.926807498269 0.618512392495863 0.537208027462451 C11orf84 other 1 1 1 3.13087088471194 0.618512392495863 0.00180734043254021 70.2920009120491 27.1398545279629 2.5899918085274 0.0105502542692996 -160.035994859358 97.8132196342352 -1.63613870863059 0.103921153291686 ATG16L2 other 1 1 1 2.5899918085274 -1.63613870863059 1.01495032536173e-08 214.940293404613 38.9563860153495 5.5174597900309 1.42359398319048e-07 -219.790223990385 149.735035397051 -1.46786103471087 0.144181424319044 C2CD3 other 0.000108132807664038 1 0.00164083442502535 5.5174597900309 -1.46786103471087 0.312045007094463 68.6084862541783 61.079016187295 1.12327425254845 0.263057826495349 -60.5237942560886 133.892931750313 -0.452031286976037 0.651878381701838 TRANK1 other 1 1 1 1.12327425254845 -0.452031286976037 3.52929131070584e-06 1501.35369400428 744.678389592257 2.01611019600869 0.0455047102695829 -5613.38928635605 1618.97666792131 -3.46724532699003 0.000679592369136423 RPSA essential 0.0304934012459312 1 1 2.01611019600869 -3.46724532699003 0.769970940768669 3.02083495691716 24.7547797795044 0.122030370854612 0.903031022135263 -31.809076708829 53.7428312114187 -0.591875716106125 0.554785162273066 ENTPD3 other 1 1 1 0.122030370854612 -0.591875716106125 8.71956342957122e-08 1667.76150421945 370.291851288995 4.50391089734741 1.29514629689381e-05 -1352.22149768832 810.225428690896 -1.66894477734814 0.097121251689597 CTNNB1 og 0.000872043538591418 1 0.130084494060014 4.50391089734741 -1.66894477734814 9.18052937742097e-11 146.280426793085 21.4756999163119 6.81143931807212 1.94411485165106e-10 21.5390992036562 48.0644119772277 0.44812988066641 0.654677257494431 ULK4 other 1.08899439474968e-06 1 2.511601976848e-06 6.81143931807212 0.44812988066641 8.97367149003095e-06 115.391780008116 23.3055609512491 4.95125520683645 1.91748746408459e-06 31.3355353160939 78.3582978565236 0.399900663660028 0.68978380993385 FADD other 0.0744904470387469 1 0.0205976503391966 4.95125520683645 0.399900663660028 6.47905814540457e-05 1682.90729711928 442.114046001132 3.80650040943275 0.000206841411672016 -1865.46282802371 1404.88628500115 -1.32783902009705 0.186303548690373 LTBP3 other 0.486651528775946 1 1 3.80650040943275 -1.32783902009705 0.0322058259099197 39.2515815573803 16.7815088531499 2.33897809194987 0.0207115624762871 -27.6468743482594 51.0020700944832 -0.542073572642101 0.588605665354489 NAALADL1 other 1 1 1 2.33897809194987 -0.542073572642101 0.000279973402591132 126.869180679896 32.0430554456964 3.95933468001833 0.000117699930254642 -11.4275264365329 97.3846972989006 -0.117344169602527 0.906750834519592 SAC3D1 other 1 1 1 3.95933468001833 -0.117344169602527 0.446770487734628 -5.64883632908753 25.0036883113157 -0.225920122613714 0.821583888814923 -96.1792508940917 75.9907750270604 -1.26567008771581 0.207675190934332 BATF2 other 1 1 1 -0.225920122613714 -1.26567008771581 0.0650076773353802 410.445962233829 235.495456831785 1.74290395133615 0.0834850235819985 -744.549216552834 715.143719970644 -1.04111830358155 0.299565477977345 SF1 essential 1 1 1 1.74290395133615 -1.04111830358155 0.000653437060547672 130.45371944247 36.1811168213399 3.60557470037872 0.000428505684067041 -54.0145563556573 109.873450742567 -0.491606989592174 0.623745713563704 MAP4K2 other 1 1 1 3.60557470037872 -0.491606989592174 0.228280903595858 11.8180996593569 8.20772816689736 1.43987464241573 0.152073338211953 -12.7326299039865 24.9447848192739 -0.510432541159807 0.610530025667622 MAJIN other 1 1 1 1.43987464241573 -0.510432541159807 0.112497910778363 7.39587187607792 20.3188982761895 0.363989807692708 0.716395828215012 -115.390423630491 60.9679296361228 -1.89264133322519 0.0603986304150698 CCDC88B other 1 1 1 0.363989807692708 -1.89264133322519 4.99104555616711e-05 197.791775735945 624.896522249893 0.316519245496535 0.75203429044285 -3843.61192237387 1266.15079445695 -3.03566679356102 0.00281595696866369 SCARA3 other 0.379918387735441 1 1 0.316519245496535 -3.03566679356102 1.23083420040322e-07 30.0880609089807 48.6146463228705 0.618909386055246 0.536890490381497 -317.972044595658 89.7065391968458 -3.54458044466437 0.000521013209210964 PBK other 0.00121532568947814 1 1 0.618909386055246 -3.54458044466437 0.00733414693386853 14.8154333780324 5.44157383699637 2.72263757174528 0.00722364241502085 8.89132024868947 10.0411047621136 0.885492230121684 0.377271759325076 SCARA5 other 1 1 1 2.72263757174528 0.885492230121684 0.0196995890832146 56.5283832748594 342.693513455836 0.164953175520623 0.869200007376345 -1141.3892448381 637.368045739193 -1.79078517109273 0.0753179010327389 PNOC other 1 1 1 0.164953175520623 -1.79078517109273 9.33062920699273e-06 375.872088284947 94.3235894695079 3.9849213796773 0.000103624594937124 -553.621878300497 310.275181203602 -1.78429314311547 0.0763322868951594 COPS6 essential 0.0773415854967627 1 0.94692154853544 3.9849213796773 -1.78429314311547 4.5248567096685e-18 632.20285856189 77.8358949855626 8.12225334698283 1.50804886382428e-13 -434.950621861377 209.612879217949 -2.07501859372452 0.0396813966071329 PAFAH1B2 other 6.31308008132949e-14 1 2.06859062650777e-09 8.12225334698283 -2.07501859372452 3.07320701934204e-13 98.8089464639104 12.4893748177363 7.9114405569437 4.38588471714307e-13 -22.3140152744793 39.3605505183537 -0.566913190507189 0.571587965071247 ANKS3 other 3.95829064091254e-09 1 5.987171227372e-09 7.9114405569437 -0.566913190507189 1.79517934925716e-15 237.779519259831 27.966528407294 8.50228944389876 1.41431104175578e-14 -114.317569068325 88.1371542020696 -1.29704175388092 0.196531848613124 NUDT16L1 other 2.42762103400046e-11 1 1.9637708814779e-10 8.50228944389876 -1.29704175388092 1.51964092575972e-05 24.1003018898035 7.27013400872987 3.31497354255977 0.001177148215862 -40.4054499753966 21.8024946549262 -1.85324893389056 0.0660297800435865 KIAA1586 other 0.123121307805052 1 1 3.31497354255977 -1.85324893389056 0.00169906957964298 84.5582898763092 39.7439798138177 2.12757479931366 0.034934119641224 -241.347293453433 123.973735752561 -1.94676148127969 0.0533482274746346 RAB4A other 1 1 1 2.12757479931366 -1.94676148127969 0.00614744963627245 6.57423586343826 5.21577893301806 1.2604514010018 0.209490186661659 -21.9971179600022 10.5573399848077 -2.08358525837537 0.0389172303464676 KCNJ4 other 1 1 1 1.2604514010018 -2.08358525837537 3.06196131392198e-09 886.964762230585 166.554078118253 5.32538603828625 3.58735315291372e-07 -453.242754508577 323.784002698255 -1.39983059920032 0.163615215911838 SETD5 other 3.36938222983975e-05 1 0.00403110873792915 5.32538603828625 -1.39983059920032 1.01805994608494e-22 1201.90504321595 102.531557406044 11.7222938344356 4.74869383062844e-23 249.31428479888 326.799948005506 0.76289572969785 0.446700221828988 VASN other 1.45613114088528e-18 1 6.8452421568509e-19 11.7222938344356 0.76289572969785 0.119585883978349 -0.140785799961753 3.3577470877083 -0.0419286492651957 0.966610244295472 -19.4594584605875 10.2725921056136 -1.89430849200695 0.0600710931102564 FAM83B other 1 1 1 -0.0419286492651957 -1.89430849200695 9.24328503856782e-18 56.443317632222 6.57556224075037 8.58380098395677 1.00492739472081e-14 9.49160654041852 10.0701066716688 0.94255273056066 0.347405399144888 THAP9 other 1.28527878461285e-13 1 1.39785400605665e-10 8.58380098395677 0.94255273056066 7.00862799207798e-08 534.859058375866 105.546579992167 5.06751671551613 1.12720765227332e-06 -400.183175791985 333.511406031094 -1.19990851453721 0.231993986251362 RNF187 other 0.000706679960441222 1 0.0122820545791701 5.06751671551613 -1.19990851453721 2.86886610006405e-08 258.754004472646 43.1150102771421 6.0014830753694 2.88594724235937e-08 80.2690751077254 121.261188189292 0.661951909809951 0.509466146270124 HOOK3 other 0.000297042396000632 1 0.000344293506013473 6.0014830753694 0.661951909809951 1.91245826771121e-07 556.642933504383 126.165818399122 4.41199479040717 1.90145353491561e-05 -234.896015964649 185.325174538358 -1.26748034394017 0.206872293671794 MAPK1IP1L other 0.00185967441952238 1 0.187882623785011 4.41199479040717 -1.26748034394017 0.504043564347728 -368.399825584063 314.21734781357 -1.17243630292061 0.242868299744901 -378.314912562533 680.372499454602 -0.556040864182189 0.579005919989388 DDIT4 other 1 1 1 -1.17243630292061 -0.556040864182189 1.83333535718313e-13 471.088953448155 77.2598287025188 6.09746308475568 8.72658919064706e-09 -169.173894998963 137.375191989742 -1.231473401774 0.220073059956733 RBPJ other 2.37563595583791e-09 1 0.000106499294482657 6.09746308475568 -1.231473401774 0.00118554067675215 135.806901279708 86.1879509496596 1.57570634622732 0.117243183882598 -301.68435786106 162.129140457756 -1.86076578836651 0.0647748420466171 LMBRD1 other 1 1 1 1.57570634622732 -1.86076578836651 2.48157555307677e-13 39.0761594168145 7.74040399577077 5.04833590574407 1.25887060608312e-06 -33.9433408469618 14.0595926166637 -2.41424782157141 0.0169562785549831 ZCCHC4 other 3.20545114190926e-09 1 0.0136662992996384 5.04833590574407 -2.41424782157141 1.15017918528225e-24 265.236320862508 22.5106703945271 11.7826931057101 1.30856169061046e-22 28.3924524248556 68.3411624430768 0.415451704505385 0.678456523234928 TTC39C other 1.65476279386558e-20 1 1.88459054681718e-18 11.7826931057101 0.415451704505385 0.178707111998451 47.2375033703579 40.1632405860903 1.17613774887272 0.241507838088902 -69.3500371561411 91.8213436878477 -0.755271425692711 0.451337059853736 GLYCTK other 1 1 1 1.17613774887272 -0.755271425692711 0.451032166265247 -22.6826977082935 30.1229453162482 -0.753003979861775 0.452568030016991 -117.739366987822 96.7388875963318 -1.2170841521263 0.225386973937345 GNG4 other 1 1 1 -0.753003979861775 -1.2170841521263 0.0438704791908326 118.82943537597 47.0323971166367 2.52654431117518 0.0125422289257636 75.1985978057267 78.5979786627997 0.956749767425229 0.34021280191026 UBTD2 other 1 1 1 2.52654431117518 0.956749767425229 7.18501649246056e-06 267.177667840723 54.6656623619134 4.88748615304204 2.55447006520067e-06 50.9376226709327 169.633433380402 0.300280561772899 0.764370770472701 POLR2J3 other 0.0601314030254024 1 0.0271974427841915 4.88748615304204 0.300280561772899 1.06573398460332e-13 468.447583055017 56.2056097315372 8.33453431592558 3.78439292029707e-14 -201.036509052557 226.073547299335 -0.889252685482804 0.375236495530817 NKIRAS2 other 1.3889711021335e-09 1 5.22511130505417e-10 8.33453431592558 -0.889252685482804 2.29274987216832e-08 240.183898751977 39.8077738992454 6.03359281932945 1.12230431162737e-08 -171.397398488309 160.117196459175 -1.0704496598653 0.286070352409663 DNAJC7 other 0.000238858681682495 1 0.00013634875081961 6.03359281932945 -1.0704496598653 4.06497523523146e-15 1572.31228366897 205.275367361463 7.65952731630163 1.84139849208496e-12 -1205.19724472939 668.970041562337 -1.80157132584701 0.0735440152283975 IRF2BP2 other 5.46088773100994e-11 1 2.4904914605449e-08 7.65952731630163 -1.80157132584701 2.36865772390967e-05 515.286201197636 213.559729985219 2.41284347584304 0.0171321293083187 -1186.61050821192 484.602568617604 -2.44862612180717 0.0155854142278877 NT5DC2 other 0.188189856164623 1 1 2.41284347584304 -2.44862612180717 0.751126904366042 -3.91264555988368 6.90601620763993 -0.566556092868016 0.571845965806852 -7.67503588866082 11.5236113955785 -0.666026961964861 0.506396816369586 FOXI1 other 1 1 1 -0.566556092868016 -0.666026961964861 4.98960327699605e-05 14.6090590597157 20.8945353010362 0.69918085514882 0.485590777444922 -172.619888642497 47.3967253583047 -3.64202141260906 0.00037911100502415 SMIM4 other 0.379858497477709 1 1 0.69918085514882 -3.64202141260906 0.121889131739292 26.8981474197608 30.5456921078218 0.880587263330433 0.379895865565021 -141.926063955318 99.545080257672 -1.42574664250551 0.155939415127096 COA6 other 1 1 1 0.880587263330433 -1.42574664250551 0.0530935857268454 111.532707390727 54.2484635326724 2.0559606692557 0.0414528734446658 -92.1188466440615 153.422710938126 -0.600425100565536 0.549094238184974 KIF5C other 1 1 1 2.0559606692557 -0.600425100565536 2.94752968574555e-05 119.414553823929 36.8508938009174 3.24047917179573 0.00148011932307934 -102.567351835755 59.0668982088343 -1.73646077491868 0.0846062973796506 MGAT2 other 0.231351605034168 1 1 3.24047917179573 -1.73646077491868 0.00018413276100765 321.187284706197 77.7268173169564 4.13225828347572 6.13129995891617e-05 144.372154777432 300.962985566322 0.479700699758036 0.63218348370449 BMI1 other 1 1 0.57413492815291 4.13225828347572 0.479700699758036 1.38176662677977e-17 321.271064713102 45.5183080403592 7.05806253668842 6.58879602856548e-11 -16.5055935190937 72.6100881177818 -0.22731818603938 0.820498749203371 THAP11 essential 1.91830660795835e-13 1 8.63132279742078e-07 7.05806253668842 -0.22731818603938 0.298771464372557 75.6453715197733 68.4956399419808 1.10438228745433 0.271117038131267 -142.359181251449 203.244086911405 -0.700434553421987 0.484692658029904 MMADHC other 1 1 1 1.10438228745433 -0.700434553421987 3.903611591236e-11 175.547208940156 51.8069907582651 3.38848495870511 0.000897938569935099 -491.617003044223 122.030305544901 -4.02864682546692 8.88628495217348e-05 PDHB other 4.69916763352989e-07 1 1 3.38848495870511 -4.02864682546692 0.000809803837628004 34.7172472081575 26.0918693820272 1.33057722694533 0.185347379098175 -149.723922587511 61.458863877718 -2.43616482864718 0.0160153283486226 PXK other 1 1 1 1.33057722694533 -2.43616482864718 0.255610452501265 9.02230176211455 5.47082723525858 1.64916590748238 0.101220413334296 7.85038449648349 15.5202024765595 0.505817144353631 0.613732523507987 HIST1H1E other 1 1 1 1.64916590748238 0.505817144353631 1.76914783613807e-07 60.0789541644819 19.3545145319132 3.10413129016588 0.0022817072484035 -123.083082256638 45.5891625325832 -2.69983205259953 0.00773452514073569 KCTD6 other 0.00172544988458546 1 1 3.10413129016588 -2.69983205259953 2.33301897469502e-05 61.381441236225 30.7529313989449 1.99595415604286 0.0477135612584533 -184.771255309979 69.2602529898229 -2.6677819865476 0.00845780121575098 MPLKIP other 0.185498338678001 1 1 1.99595415604286 -2.6677819865476 0.00241129009623432 39.2754004836323 22.5859039578253 1.73893418465656 0.0840979789536548 -93.7421487991359 53.2006341352975 -1.76204946280781 0.0800979631375803 ACOX2 other 1 1 1 1.73893418465656 -1.76204946280781 0.00976122877659258 270.220271713062 309.184170763845 0.873978350979215 0.383517903086806 -1530.60805855138 727.668736867156 -2.10344072928175 0.0370850881647446 FAM107A other 1 1 1 0.873978350979215 -2.10344072928175 3.33657221458967e-05 81.4627457915619 46.94389528148 1.73532139382775 0.0846461054474991 -173.56244404408 76.5804755876317 -2.26640593065358 0.0247923859185919 IRF2 other 0.260052438405119 1 1 1.73532139382775 -2.26640593065358 0.507114332721816 41.2156904503617 49.0690323515278 0.839953194004211 0.402220079160521 116.820860259422 106.679097453193 1.09506794722067 0.275174685801366 CX3CR1 other 1 1 1 0.839953194004211 1.09506794722067 0.107485643699186 129.88713592233 126.857018428741 1.02388608475212 0.307515828419688 -256.389563106795 203.115334033415 -1.26228560894677 0.208779334175487 DEGS2 other 1 1 1 1.02388608475212 -1.26228560894677 2.99840000959965e-09 21.3703609317779 3.39560021177408 6.29354446900938 2.95993663275246e-09 5.35900945117734 7.54980991061048 0.709820447750056 0.478868398274995 SCN11A other 3.30093857056825e-05 1 3.67505732322546e-05 6.29354446900938 0.709820447750056 2.46060078506977e-06 490.200668522388 256.603380666407 1.91034376573419 0.0579475288241658 -1934.43340221607 581.042982433833 -3.3292432069539 0.00108966067506568 ARF4 essential 0.0216163778968379 1 1 1.91034376573419 -3.3292432069539 5.62388641737735e-07 1795.0049122807 441.956681684317 4.06149513440967 8.02859737655207e-05 -1549.96792982457 945.640844724571 -1.63906618297141 0.103413184959238 SEPT2 other 0.00524202452963743 1 0.742083255514708 4.06149513440967 -1.63906618297141 0.226193064832137 -68.4785327835484 46.544464650018 -1.47124976725932 0.143277346248441 115.409295347402 206.498993623414 0.558885509911349 0.577056946832244 FILIP1L other 1 1 1 -1.47124976725932 0.558885509911349 1.4869410142579e-06 58.4172213688343 11.6922429742681 4.9962373769855 1.59811786219632e-06 -92.1929410593387 86.1920249278975 -1.06962263778419 0.286496034214087 MFSD2A other 0.013352730308036 1 0.0172468879688227 4.9962373769855 -1.06962263778419 0.130324218736799 59.6924349083478 58.1539550505195 1.02645529193142 0.306447263739613 -132.92134740658 121.779230513635 -1.09149439396152 0.276930263214083 DTYMK essential 1 1 1 1.02645529193142 -1.09149439396152 0.261451656089786 4.16693997109689 221.800345855494 0.0187868957328484 0.985034961784973 -951.624603023514 651.476546083801 -1.46071966633946 0.146090740017913 TAP1 other 1 1 1 0.0187868957328484 -1.46071966633946 6.44156902814874e-13 283.842360010736 41.7013921298544 6.80654399083073 2.69672378848875e-10 -98.382226032043 87.3261920106612 -1.12660616210119 0.261836406371941 ING5 other 8.22395117823749e-09 1 3.4644810510715e-06 6.80654399083073 -1.12660616210119 1.09623609817827e-07 312.516343264843 69.9212135077722 4.46954976303586 1.60517925274303e-05 -222.114635195239 146.420850828787 -1.51696041880649 0.131531481617859 ATG4B other 0.00108713733856339 1 0.159683232062877 4.46954976303586 -1.51696041880649 0.798505264595168 -1.34507790768673 11.476018815042 -0.117207711957016 0.906849174281485 -12.2815305637848 18.9382557821608 -0.648503785409507 0.517631295706119 BDKRB2 other 1 1 1 -0.117207711957016 -0.648503785409507 0.172657205222657 -26.8027068894723 14.383729491871 -1.86340454362827 0.0643220977137563 -24.2439124538069 24.215141758025 -1.00118812832357 0.318316658739819 MLKL other 1 1 1 -1.86340454362827 -1.00118812832357 6.89550591692709e-13 407.391931607307 58.0046241013844 7.02343887092932 6.52413335365e-11 133.659809138106 97.6639689645625 1.36856827093116 0.173127419133988 RFWD3 other 8.79521779704051e-09 1 8.54791951995223e-07 7.02343887092932 1.36856827093116 0.362109425197726 4.31542737293557 5.55651572329611 0.776642699820467 0.438553175290632 13.5959896166435 9.52196688833062 1.42785516648936 0.155345265867744 RHOH other 1 1 1 0.776642699820467 1.42785516648936 0.721511064863469 0.462380916660412 5.40897999677117 0.0854839391043089 0.931997927014289 -8.11754557047483 12.3246583898038 -0.658642642557173 0.511199362600166 KLHL30 other 1 1 1 0.0854839391043089 -0.658642642557173 1.01204758178515e-14 192.555732771375 32.827561910134 5.86567267159528 2.58898310390904e-08 -180.676664525643 66.7542053211124 -2.70659599131652 0.00755498463500373 COG7 other 1.35007147410139e-10 1 0.000309538819903365 5.86567267159528 -2.70659599131652 4.29440501083555e-17 100.677842158307 18.4261078868967 5.46386913483244 1.87960164342766e-07 -118.112427364016 38.584222549483 -3.06115866951941 0.00261044306172097 CDC40 essential 5.93014387946281e-13 1 0.0021500763199169 5.46386913483244 -3.06115866951941 0.228113926980564 79.6755640535371 204.388306352889 0.389824474184801 0.697230568338778 -1016.09430975144 672.598587542918 -1.51069944030562 0.133011672500287 STIP1 other 1 1 1 0.389824474184801 -1.51069944030562 0.564565245992454 -2.93825191429171 10.3063425332202 -0.285091622447139 0.775952090128382 -21.5937034658122 20.9577460383955 -1.03034474347821 0.304443009611306 SCNN1B other 1 1 1 -0.285091622447139 -1.03034474347821 0.0801482424236026 -2.71356783919584 41.7061953072662 -0.0650639028375498 0.948215935199473 -119.226644586569 75.2824489836916 -1.58372431019609 0.115512844341756 HR other 1 1 1 -0.0650639028375498 -1.58372431019609 0.685316758731501 -63.2267273879467 72.6819419141272 -0.8699097151621 0.385739675906539 -90.9392429173424 195.97685773847 -0.464030518535512 0.643298599816964 RAB31 other 1 1 1 -0.8699097151621 -0.464030518535512 1.40805502740132e-08 277.710500037138 72.928994121548 3.80795736157129 0.000209502835173712 -94.5011842767662 131.714285612239 -0.717471030856693 0.474287512726468 REEP4 other 0.00014883141639632 1 1 3.80795736157129 -0.717471030856693 0.794718157266284 -4.93612281393028 45.7971037470548 -0.107782423124251 0.914325973665756 -96.1393932046191 147.51898709413 -0.651708604420351 0.515680969246335 TNXB other 1 1 1 -0.107782423124251 -0.651708604420351 7.8542038765693e-08 529.05880711267 130.290458620053 4.06061052141574 8.05588658618355e-05 -12.0420301411366 234.931911244053 -0.0512575327777715 0.959192340600975 BMP1 other 0.000788090816974963 1 0.744444479429222 4.06061052141574 -0.0512575327777715 1.58264295050163e-06 1305.11794354838 296.883882160003 4.39605523227765 2.06816903504477e-05 -436.642387030126 628.250534658809 -0.695013156283675 0.488115161828181 ATXN2L other 0.0141899766941976 1 0.20369396826156 4.39605523227765 -0.695013156283675 0.000832556795082096 11.5120127442375 4.37925804525622 2.62875871329568 0.00948671333262165 -0.117179795615413 7.74343185435911 -0.0151327987150099 0.987946893918894 PHYHIP other 1 1 1 2.62875871329568 -0.0151327987150099 0.0118495889044157 9.17000957738419 5.35533312535169 1.71231356906149 0.088813249438509 -7.42003985072487 8.71257865201945 -0.851646814000929 0.395707309343673 CCDC110 other 1 1 1 1.71231356906149 -0.851646814000929 2.69971162746226e-31 333.541885717093 30.5983763999752 10.9006399998846 9.63083549913718e-21 39.0469513093889 55.0965712435299 0.708700204533586 0.479610494983166 POLR3D essential 3.91728157144775e-27 1 1.38202489412619e-16 10.9006399998846 0.708700204533586 0.000327616361734852 38.717767846024 9.4336722881155 4.10420954465426 6.55882110185182e-05 33.7742967441991 33.1192502702715 1.01977842096612 0.309432922761747 CAVIN2 other 1 1 0.612134773435831 4.10420954465426 1.01977842096612 3.2004461452468e-05 44.171846707684 11.1097785106885 3.97594305459709 0.000108373155562277 -5.31974387663328 29.7920877031794 -0.178562305859 0.858520742165969 MTCL1 other 0.249986848405227 1 0.986954327705653 3.97594305459709 -0.178562305859 1.14915690331495e-06 50.6652879526097 9.33746098142783 5.42602406086437 2.15932620665669e-07 -6.66591888955117 37.5380496394441 -0.177577656633146 0.859285040479309 HEXIM2 other 0.0104324437291355 1 0.00246033627986463 5.42602406086437 -0.177577656633146 1.91390579161418e-05 341.027767549513 87.6641317236099 3.89016306720194 0.000177806921169916 -96.8779095762862 194.389519955147 -0.498370023232938 0.619285809544271 FNTA other 0.153418688255793 1 1 3.89016306720194 -0.498370023232938 0.0106726178562121 -330.182778762545 272.872351678934 -1.21002650774617 0.228122785821097 -2121.64704972291 699.968387671016 -3.03106124089719 0.00285963372443235 SERINC2 other 1 1 1 -1.21002650774617 -3.03106124089719 1.13650837867121e-20 266.641938971648 28.3144199049323 9.41717823875316 5.66890061380681e-17 63.1471648246024 44.8286810596269 1.40863311906523 0.160921008890773 TRAPPC11 essential 1.61145523011791e-16 1 8.0135579076773e-13 9.41717823875316 1.40863311906523 0.00922387977027041 172.984550758928 92.7237893556542 1.86558974736702 0.0640649507202682 -54.066244928786 167.713497203282 -0.322372652352801 0.74762228277165 GFRA2 other 1 1 1 1.86558974736702 -0.322372652352801 0.000325368450079555 36.286400768861 13.7407375454586 2.64078988837494 0.00910706311903919 -15.9231138875543 21.7549624190642 -0.731930195089679 0.465302333536847 ING2 other 1 1 1 2.64078988837494 -0.731930195089679 1.20767425126108e-15 125.229517059106 19.7841913791742 6.329776873819 2.45577051776711e-09 -36.5440893801057 31.3232341802321 -1.16667676044667 0.245109987252091 CDKN2AIP other 1.63760628471003e-11 1 3.05915333398249e-05 6.329776873819 -1.16667676044667 1.94116268334398e-08 102.538661553878 19.1867368026266 5.34424704986001 3.19079454655368e-07 -34.2752457635272 52.6221709608502 -0.651346098758017 0.515787625930179 SNRNP48 essential 0.000203395025960782 1 0.00359570637451134 5.34424704986001 -0.651346098758017 1.7774863930082e-10 439.85824304093 60.8737838257695 7.2257417790863 6.92982103440867e-11 292.977530513334 171.697118055134 1.70636254022188 0.0907623600740132 SLC20A2 other 2.0807255716554e-06 1 9.06836380562719e-07 7.2257417790863 1.70636254022188 0.0030816102780763 -7.76449257867944 5.27973582918957 -1.47062141551716 0.143433793403821 -32.4929504698077 9.67943148016824 -3.35690691507875 0.000993009446345317 DYNLRB2 other 1 1 1 -1.47062141551716 -3.35690691507875 1.59658086336175e-16 287.73946424256 30.3793933511724 9.47153423758065 4.46197239503423e-17 -94.0335545517073 119.122832173652 -0.789383133660129 0.431093960777823 TMUB2 other 2.19034928644598e-12 1 6.31012136105742e-13 9.47153423758065 -0.789383133660129 2.69392475054461e-06 1339.2169061011 254.089771351832 5.27064469764396 4.45868325155021e-07 281.035538996199 1012.53097732129 0.277557472601673 0.7817195663519 STAT3 other 0.0235664537177642 1 0.00498480787523314 5.27064469764396 0.277557472601673 4.12017800045751e-12 93.446970433295 12.5703245220156 7.43393460285234 6.5442495691473e-12 -9.05611064673523 56.4924558684033 -0.160306549034282 0.872846990701813 ZSWIM1 other 5.13085766396973e-08 1 8.76013247326058e-08 7.43393460285234 -0.160306549034282 3.02814635897e-05 238.788925298166 54.5145933456164 4.38027527389356 2.38199382719895e-05 -86.1891978120093 196.423135881237 -0.438793512919586 0.6615231435237 ADAM9 other 0.23719470429812 1 0.232911356423514 4.38027527389356 -0.438793512919586 0.0235410160366041 15.6424032027772 6.21121182617077 2.51841406162779 0.0128373648122198 39.6609367563482 26.0368369439916 1.5232624777604 0.129798521331167 GDNF other 1 1 1 2.51841406162779 1.5232624777604 0.000712221711233059 144.217127741651 56.8054030404254 2.53879243914561 0.0121093499559273 684.487655681695 226.777385711078 3.01832413110959 0.00297258085790778 AXIN2 ts 1 1 1 2.53879243914561 3.01832413110959 0.000200010202927828 557.61878332679 155.161142347803 3.59380431781594 0.00043968598244838 -943.906909173811 797.007391191686 -1.18431387162229 0.238137446690479 NDUFS5 essential 1 1 1 3.59380431781594 -1.18431387162229 0.543194299987737 2.37068054189148 17.7563642876926 0.133511596376441 0.893970163737209 -87.3153273163907 83.8541400834609 -1.04127628319228 0.299445343439036 VWA3B other 1 1 1 0.133511596376441 -1.04127628319228 1.11497232168017e-20 19.4495964710011 2.0084125810636 9.68406424774588 1.1114996944594e-17 -15.3752443731516 8.95363032207884 -1.71720786095419 0.0879130996569302 ZNF30 other 1.58114224937465e-16 1 1.57655116662121e-13 9.68406424774588 -1.71720786095419 0.0664851778605949 -18.493770749295 26.8728893784529 -0.68819435412567 0.492445267691743 -163.370696938326 71.9955534763394 -2.26917759569716 0.0247538586834871 LDLRAD4 other 1 1 1 -0.68819435412567 -2.26917759569716 0.0021212531706357 8.21355410088566 4.18704337681586 1.96165966332354 0.0518002775881851 -4.96547664888058 6.56647064253339 -0.756186529901984 0.450817034690569 KCTD19 other 1 1 1 1.96165966332354 -0.756186529901984 0.269221084107289 20.6616727542872 17.6028265181881 1.17377017451933 0.242322967491351 -46.0603603045875 60.9246540258708 -0.756021696652206 0.450806260423924 SLC16A4 other 1 1 1 1.17377017451933 -0.756021696652206 0.37262749491863 7.61656753227915 16.7717795239494 0.454129958088408 0.650387372998972 96.5726098940956 69.5801840643818 1.38793265917115 0.167202068852315 IL7R other 1 1 1 0.454129958088408 1.38793265917115 1.79963064961978e-05 63.2600783307453 42.4194130762721 1.49130017940137 0.13816505570218 -150.162547549913 66.8964657320252 -2.24470076119472 0.026378592405716 TMEM208 other 0.14469030422943 1 1 1.49130017940137 -2.24470076119472 0.566997557632926 13.0911272860088 14.1525508489703 0.925001254241121 0.356412451209809 -8.52839085857394 37.609705022538 -0.226760376170545 0.820910800388503 LRP1B other 1 1 1 0.925001254241121 -0.226760376170545 3.44172577371882e-06 823.812479692881 205.055687449436 4.01750612206757 9.22194790666108e-05 -1453.6368562331 692.835920214912 -2.0980968420087 0.0375507780017145 AHCYL1 essential 0.0297778113942152 1 0.847128134705887 4.01750612206757 -2.0980968420087 2.21579146018296e-09 185.210067494263 28.4187844754267 6.51717062896944 1.02505982913237e-09 -87.183201001053 117.580306638477 -0.74147791831428 0.459563024016696 DNAJC21 other 2.45465377959069e-05 1 1.2932154804334e-05 6.51717062896944 -0.74147791831428 0.000154458269647108 155.195040005859 43.1360109841452 3.59780694749223 0.000431113399359714 -189.694930149953 189.16091914704 -1.00282305142797 0.317509214534379 PKIG other 1 1 1 3.59780694749223 -1.00282305142797 0.153657964983621 243.280321613519 132.039373124842 1.8424831613181 0.0673027728251195 149.042886345054 198.319492488372 0.751529183919189 0.453466529740894 NPNT other 1 1 1 1.8424831613181 0.751529183919189 0.365626315519668 17.1321920140071 13.2584174579067 1.29217473113959 0.198310619793489 -19.3672162508308 66.6019537963602 -0.290790512092893 0.771618637094818 FAM178B other 1 1 1 1.29217473113959 -0.290790512092893 3.35252947466227e-17 547.034792207863 57.476702009077 9.51750488609233 4.74045596891754e-17 -200.511849122093 286.423963092649 -0.700052631620192 0.484993391788684 SEMA4C other 4.63453674577312e-13 1 6.70205664885562e-13 9.51750488609233 -0.700052631620192 1.20086705171933e-26 333.983402990976 25.9857271320511 12.8525710015263 7.28048796728566e-26 -165.383455714764 129.494815966143 -1.27714344764199 0.203551591977296 CNNM3 other 1.73513280302926e-22 1 1.05290416982885e-21 12.8525710015263 -1.27714344764199 0.0282384816309319 95.4284502524816 51.8563294367327 1.84024691467816 0.0676822192936032 -234.893944414256 174.126030433186 -1.34898810838272 0.17934697694143 GSTM4 other 1 1 1 1.84024691467816 -1.34898810838272 3.30436972267564e-07 151.603570455164 40.5029589353095 3.74302457006419 0.000255165882482399 -46.6467702371222 60.8343259304426 -0.766783711723176 0.444368968591701 TET2 other 0.00314212516929226 1 1 3.74302457006419 -0.766783711723176 0.000286713925792608 52.3229974160206 16.6563771750094 3.14131919962307 0.00201051550481042 1.72924741602055 25.0387270351854 0.0690629125670222 0.945027425292246 CXXC4 other 1 1 1 3.14131919962307 0.0690629125670222 1.23358222472318e-20 358.399447364874 39.9896888886419 8.96229646504373 1.07866320525272e-15 -176.274430516241 94.7453463295872 -1.86050753250763 0.0647457897419544 TCTN2 other 1.74872616176758e-16 1 1.51217794744379e-11 8.96229646504373 -1.86050753250763 0.596143451770806 3.49569084842576 4.93783903432024 0.707939409148234 0.480067029496045 -13.7746419360949 19.4277241477554 -0.70901984356651 0.479398235721168 SHOX2 other 1 1 1 0.707939409148234 -0.70901984356651 0.0129647001390918 28.9878112303365 27.3613148036023 1.05944511213767 0.291331895469097 -100.05729763517 53.6566022558685 -1.86477140609899 0.0644340647119568 PPIP5K1 other 1 1 1 1.05944511213767 -1.86477140609899 0.169630191018703 -19.8572416974179 34.3159949324828 -0.578658486705318 0.563654141481686 -88.3140934250265 51.4879673650171 -1.71523751945645 0.0882872287516027 TSPAN5 other 1 1 1 -0.578658486705318 -1.71523751945645 9.54237263089487e-05 56.6208342259083 13.2818823011866 4.2630127975799 3.71597074629285e-05 -30.5454907121212 53.3500797544538 -0.572548173361844 0.56788228434526 ABHD15 other 0.701841507002318 1 0.355878518372467 4.2630127975799 -0.572548173361844 3.72582852033287e-18 307.40593141798 36.9606877940253 8.31710527496383 5.07262393360988e-14 -115.674945937597 85.1130142188466 -1.35907471964473 0.176162827403847 ZBTB5 other 5.20237436294079e-14 1 6.99616292923475e-10 8.31710527496383 -1.35907471964473 0.000262191936340177 318.681130270549 137.324859267488 2.32063686043768 0.0216449164325283 -194.180995364124 221.249772895724 -0.877655117212898 0.38152519131932 CHTF8 essential 1 1 1 2.32063686043768 -0.877655117212898 1.38192066301832e-10 59.1164341466411 11.0556936262888 5.34714836942216 3.64313631948027e-07 -27.8463216766026 18.0118243544715 -1.54600228875148 0.124410900774217 ADAL other 1.62569146797476e-06 1 0.00409269934130414 5.34714836942216 -1.54600228875148 4.85125149554053e-11 114.331626820724 25.3540005935857 4.50941169614268 1.38342482647134e-05 -117.529832216827 41.3064816022881 -2.84531210739375 0.00511845230744994 LCMT2 other 5.81519516770443e-07 1 0.138425488136722 4.50941169614268 -2.84531210739375 6.67865782965859e-08 402.83399151316 71.3963317706866 5.6422225277203 8.05538195233394e-08 264.958694105816 115.029589501222 2.30339598058812 0.0226212053269424 SNTB2 other 0.000674277294482331 1 0.000940063073837371 5.6422225277203 2.30339598058812 0.0889843355922526 7.90590325014631 6.95103347300309 1.1373709076286 0.257173007008908 -54.757090467078 28.3749232771165 -1.92977052069205 0.0554977118151091 IL12A other 1 1 1 1.1373709076286 -1.92977052069205 1.57086286413797e-26 159.027779027059 12.6696840660381 12.5518346154616 6.32493612280497e-25 -50.7226594708042 60.6833051225204 -0.83585855069025 0.40460974131038 ZNF507 other 2.2691114072473e-22 1 9.13447274855494e-21 12.5518346154616 -0.83585855069025 0.0392241125696066 32.4244390152878 138.916181009229 0.23341009506397 0.815754967487673 -516.767044345023 265.096795713716 -1.94935228452588 0.0530821401769311 STX18 other 1 1 1 0.23341009506397 -1.94935228452588 6.21907662872276e-10 888.629961639591 149.17162062649 5.95709799161213 1.7167656819009e-08 133.595374239094 281.168490674422 0.475143476847804 0.63536674983803 NSG1 other 7.09410071038405e-06 1 0.000206801594041783 5.95709799161213 0.475143476847804 1.76036729994656e-19 49.4011724237294 5.99762789125766 8.23678516230361 7.56493283617092e-14 -10.0346774484026 11.3047238793105 -0.887653476151473 0.376129599070428 ZBTB49 other 2.48018148889471e-15 1 1.04131300489893e-09 8.23678516230361 -0.887653476151473 3.00732253278835e-12 248.006885013106 31.3593311470813 7.90855148822867 4.96645663606013e-13 143.75996872852 127.770397500322 1.12514300292568 0.262301961235593 GFM1 essential 3.76306268527806e-08 1 6.77623343424045e-09 7.90855148822867 1.12514300292568 0.000125545826128856 18.4963190184049 5.60625534890147 3.29922878415255 0.00119964768065553 -0.513982617586924 8.43731923224659 -0.060917763502717 0.951502180362849 FSTL5 other 0.909424075317439 1 1 3.29922878415255 -0.060917763502717 4.99900565408183e-17 299.077321029083 42.7650244176445 6.99350287067032 7.95954543695893e-11 -10.154579915486 68.7705198350516 -0.147658908785946 0.882807649671054 DDX19A essential 6.89862780263293e-13 1 1.04015339770179e-06 6.99350287067032 -0.147658908785946 1.71449677032272e-07 69.5326354327556 16.3226662651149 4.25988219714828 3.5353513333232e-05 -84.1370273439734 45.6885630242164 -1.84153367439852 0.0674547308842981 ANKRD49 other 0.00167386319686607 1 0.339888677185692 4.25988219714828 -1.84153367439852 7.22916033682021e-14 227.853361691045 38.0050080502021 5.99535096506403 1.40409872557324e-08 -117.046512435436 72.0940202909479 -1.62352594519038 0.106535562630539 TNIP2 other 9.46947712520079e-10 1 0.000169769576909061 5.99535096506403 -1.62352594519038 1.98249696237695e-11 98.3123374376977 14.4167851598939 6.81929683680056 1.95809930505278e-10 -32.7844503952748 28.6006441906543 -1.14628363531712 0.253455801072792 LRRC28 other 2.41111280564285e-07 1 2.52947268226718e-06 6.81929683680056 -1.14628363531712 0.610019609267356 5.4791219407471 7.29997596204034 0.750567120938258 0.454181900391084 -1.68119364534134 11.280342065466 -0.149037470280995 0.881740078285535 PLA2G4F other 1 1 1 0.750567120938258 -0.149037470280995 0.00176027271733891 51.2823416614267 15.8217907509955 3.24124762288365 0.00148066621954049 4.26394275966404 38.9827630840006 0.109380208644422 0.913054273678785 ENHO other 1 1 1 3.24124762288365 0.109380208644422 6.55292935557446e-06 225.629596664636 76.0467042809572 2.96698717976048 0.0034876685793332 -194.597308755329 112.932586402231 -1.72312806210098 0.0868725576386074 ZNF608 other 0.0550577124455366 1 1 2.96698717976048 -1.72312806210098 0.131171564235321 17.7157269403825 8.73340679782669 2.02850128827058 0.0442211907268217 10.9962856205475 33.3210614926873 0.330010063543765 0.741837950231367 SLC35G2 other 1 1 1 2.02850128827058 0.330010063543765 0.449320306663025 -75.4030139390311 60.2254726695206 -1.25201199088624 0.212427488793678 -50.4563952346233 134.350380540325 -0.375558260659179 0.707752249815677 INPP5D other 1 1 1 -1.25201199088624 -0.375558260659179 7.72691925045684e-06 281.424018166454 71.0441309930166 3.96125639419978 0.000115850356225474 -40.1725417714764 131.285629384416 -0.305993443150184 0.760042564467387 LETM1 essential 0.0644811411450623 1 1 3.96125639419978 -0.305993443150184 2.03887899490223e-08 310.675534832692 75.5801430594433 4.11054441360806 6.60169456025811e-05 -215.697613823369 135.119000424129 -1.59635294182394 0.112602268538094 TMEM129 other 0.000213307520446672 1 0.615740051635274 4.11054441360806 -1.59635294182394 0.0554918545898243 126.57083503938 66.1229037634551 1.91417538909314 0.0574403740287561 -11.2829668344609 96.5279702063967 -0.116888056491146 0.907100080155661 PPIC other 1 1 1 1.91417538909314 -0.116888056491146 3.71907269703955e-06 52.2007471693774 18.6787573019246 2.79465846285175 0.00585213430558813 -54.4301080521869 28.0949359871769 -1.93736366144525 0.0545190968935065 CEP120 other 0.032065844793875 1 1 2.79465846285175 -1.93736366144525 0.17457312981822 204.866453428864 148.372375692984 1.38075873269549 0.169393435518898 -147.183316274309 287.844574507806 -0.511329131445266 0.609867487116271 STXBP6 other 1 1 1 1.38075873269549 -0.511329131445266 4.71888886967787e-11 290.973171637831 53.695447841062 5.41895418209582 2.19941553641546e-07 -249.324288822843 122.202284018271 -2.04025882843208 0.0429895644814994 MFF other 5.65794775474377e-07 1 0.00250491435442357 5.41895418209582 -2.04025882843208 3.84653458808616e-08 703.569594494599 125.002628491745 5.62843840152576 1.03315215453389e-07 -1746.7613585911 799.336493857508 -2.18526411844582 0.0306208368601814 LGALS9 other 0.00039465444873764 1 0.0011995929666293 5.62843840152576 -2.18526411844582 4.28183503000264e-06 285.531655789866 74.5482422851376 3.8301594650313 0.000202962183423521 -120.755300648786 114.80368569381 -1.0518416714499 0.294934261229256 JMJD7-PLA2G4B other 0.0367038898771826 1 1 3.8301594650313 -1.0518416714499 0.344422247919168 31.7168362792357 35.0488519507259 0.904932244965555 0.367188259823544 -26.6123013747546 63.7093881094434 -0.417713969078444 0.676850703016896 CPLX1 other 1 1 1 0.904932244965555 -0.417713969078444 0.00519728531470923 185.953618756368 70.3203724485267 2.64437761464479 0.00905485107863475 -101.368574341054 180.264852742441 -0.562331329701235 0.574729688688229 PXDC1 other 1 1 1 2.64437761464479 -0.562331329701235 0.110955177526585 11.5776805251641 6.16517504206477 1.87791594661466 0.0622471743809919 22.0450765864333 11.8754193159821 1.85636195235352 0.0652761083566329 SIGLEC7 other 1 1 1 1.87791594661466 1.85636195235352 6.38833407516659e-17 105.372877592192 12.522353019258 8.41478254367528 2.52338984450957e-14 -66.9381540053671 39.0189184007831 -1.71553074121151 0.0882591357890792 E2F6 other 8.80759618943217e-13 1 3.4936332397235e-10 8.41478254367528 -1.71553074121151 1.13253056362986e-10 455.134859050266 65.2361730552067 6.97672530031926 8.4013411018386e-11 66.7028082865777 110.129695421492 0.605675045511479 0.545622162960801 FEM1B other 1.33823434528916e-06 1 1.09746718813318e-06 6.97672530031926 0.605675045511479 0.000952757592818035 29.1611121340455 28.1360470869322 1.03643244710055 0.301635725134314 -135.196648867612 52.9574037570662 -2.55293196561911 0.0116608700567022 COMMD8 other 1 1 1 1.03643244710055 -2.55293196561911 0.0188279253108874 101.76908195568 224.368529664231 0.453580019033768 0.650887391604259 -833.114984171649 406.915487056107 -2.04739070070532 0.0426341396346372 ATP5I other 1 1 1 0.453580019033768 -2.04739070070532 1.32173190713347e-06 559.943789422052 104.098105709442 5.37900075708356 3.47616646125021e-07 232.94303966237 466.874084516818 0.498941893301808 0.618683456241437 UQCRFS1 essential 0.0119261148813191 1 0.00390825395238361 5.37900075708356 0.498941893301808 0.187699277462857 28.2281744635948 19.9791653846936 1.41288056433132 0.160080569052622 -5.41945128385509 36.2342786025004 -0.149566970638712 0.88133805860449 MFSD7 other 1 1 1 1.41288056433132 -0.149566970638712 0.0105893154899266 40.4625039804693 14.0316636891513 2.88365691174264 0.0044792310176962 13.4102669567987 31.9338308987762 0.419939186103494 0.675100375314502 COL4A3 other 1 1 1 2.88365691174264 0.419939186103494 1.15915311471919e-09 336.793249203076 51.7992635004365 6.50189262247402 1.01752263144134e-09 35.6938930350719 87.3964421441174 0.408413571072062 0.68353012633144 MAP2K1 other 1.30393133874762e-05 1 1.28380830408953e-05 6.50189262247402 0.408413571072062 0.147530738962745 428.683632618385 955.072961192929 0.448849093249315 0.654167416654065 -2274.42403047549 1754.32842049597 -1.29646422180887 0.196742468180879 KLK7 other 1 1 1 0.448849093249315 -1.29646422180887 0.00248031286127145 631.727666999005 259.450004599573 2.43487244478563 0.016039529779171 -485.757278165503 424.039638276612 -1.14554686476888 0.253759743704359 HNRNPH1 essential 1 1 1 2.43487244478563 -1.14554686476888 1.66581855543607e-10 590.797880382843 85.5069714883244 6.90935335563269 1.18735318251757e-10 261.220463006547 195.364963499533 1.33708961078465 0.183152383677312 IRS1 other 1.95217276511553e-06 1 1.54308419599984e-06 6.90935335563269 1.33708961078465 2.78717218329434e-08 228.775204952317 41.3329379117549 5.5349369415924 1.48631741354946e-07 -44.9887569014556 74.8894529799552 -0.600735552354711 0.548987448161216 UPF3A other 0.000288751038189294 1 0.0017114945017022 5.5349369415924 -0.600735552354711 0.174651059326728 -13.2034647174716 7.2632472208793 -1.81784597383885 0.0710964581457999 -20.7365672250784 41.4235108159766 -0.500598979096686 0.617392018282245 ZBBX other 1 1 1 -1.81784597383885 -0.500598979096686 0.0414080412173647 210.162931029897 95.90651743219 2.19133106546686 0.0299204100259338 12.8225244536171 145.368337089898 0.0882071344441913 0.929825907560512 ROR2 other 1 1 1 2.19133106546686 0.0882071344441913 0.112370939241147 4.15107180978681 2.72570823047196 1.52293329248525 0.129938436499906 -7.679211100992 9.88617940347374 -0.776762264529989 0.43855569617997 C8orf46 other 1 1 1 1.52293329248525 -0.776762264529989 4.44761608997799e-08 51.4863598759049 8.48309245574782 6.06929137510692 1.01682549403541e-08 -2.73053429851776 36.8178716451502 -0.0741632847448267 0.940979932085166 HSPBAP1 other 0.000454146078947653 1 0.000123686653094468 6.06929137510692 -0.0741632847448267 6.83519778743491e-09 299.810021680051 56.2217716608706 5.33263205379765 3.46894335098996e-07 -28.2583315521081 80.7139168888017 -0.350104822580214 0.726747897471998 CHST14 other 7.36424209618238e-05 1 0.00390082679818821 5.33263205379765 -0.350104822580214 0.481539134409401 6.61008627906488 13.3503509890772 0.495124531517787 0.621222533654402 65.2559462130625 54.0353222360613 1.20765350353575 0.229044072475322 PARM1 other 1 1 1 0.495124531517787 1.20765350353575 5.71299102309692e-10 324.903412539576 49.0209700868512 6.62784542949558 5.32715153108337e-10 57.7523130300694 79.153075631499 0.729628161247178 0.466718688069882 CSNK1G1 other 6.52880614119516e-06 1 6.78199661422223e-06 6.62784542949558 0.729628161247178 0.393207291730647 7.62615919933246 7.93296454893316 0.961325258961108 0.33786687081107 41.4400339034643 32.713627524934 1.26675141336372 0.20712020921511 ARMC4 other 1 1 1 0.961325258961108 1.26675141336372 0.041116624177292 447.087846488774 205.414731017576 2.17651306833744 0.0310504901640872 -48.3379239099781 375.279432667405 -0.128805150781653 0.897680992013704 AFAP1L2 other 1 1 1 2.17651306833744 -0.128805150781653 0.000174025462068399 60.6960618145565 20.3502596358581 2.98256940700684 0.00332423406764104 -44.7673751472853 33.2600369313642 -1.3459809211778 0.180286747934218 ZNF354A other 1 1 1 2.98256940700684 -1.3459809211778 6.37965670015353e-07 94.8544919951191 22.860937144466 4.14919525808156 5.46767459358682e-05 -26.4702782964085 32.3509387186901 -0.818222881462038 0.414477989778699 ZBTB43 other 0.00591649362372239 1 0.514726886240264 4.14919525808156 -0.818222881462038 0.000866449726418033 113.381853058425 37.7656604168179 3.00224732752015 0.00311900694204913 -9.56367396802257 65.6693007942676 -0.145633863195592 0.884397243196265 CPT1C other 1 1 1 3.00224732752015 -0.145633863195592 0.830950788368574 -0.166653205970669 9.95316144920204 -0.0167437458762442 0.986662581082877 -16.7412609490525 28.8543082882849 -0.580199697798668 0.562622454280287 PCSK9 other 1 1 1 -0.0167437458762442 -0.580199697798668 1.87391343293387e-08 431.040830969466 103.54692195721 4.16275851393817 5.2310068949965e-05 -483.168635630457 216.954834332446 -2.2270471046065 0.0274042028964224 XPO6 other 0.000196592258249092 1 0.49401629116347 4.16275851393817 -2.2270471046065 4.09671217290785e-05 234.486782173797 51.1156420176699 4.58737820592645 9.58411254885042e-06 238.201201852537 85.0288319472683 2.80141684176327 0.00577802795865474 MN1 other 0.314955231853155 1 0.0974895928469065 4.58737820592645 2.80141684176327 1.27346671097108e-07 158.096720634693 65.6890143758246 2.40674520902657 0.0172872503034626 -474.25883412311 134.54026784404 -3.5250326294346 0.00055884196774518 NSMCE1 essential 0.00125586452508708 1 1 2.40674520902657 -3.5250326294346 1.96434893532731e-08 36.4703098364089 9.17893521559728 3.9732614927314 0.00010861696350696 -40.6313215898556 21.6099799519652 -1.88021098030499 0.0619678208179833 CCDC126 other 0.000205765550975536 1 0.98895745273087 3.9732614927314 -1.88021098030499 0.00650217488405676 64.1823397325175 20.6805443644109 3.10351307013797 0.00228359127419511 11.2165728997023 64.1994531502209 0.174714461717556 0.861538044620805 RAB3B other 1 1 1 3.10351307013797 0.174714461717556 1.19560857941987e-06 170.80196953635 49.3212387683033 3.4630510871539 0.00069058281519768 -234.604820621548 105.436502141999 -2.22508159750585 0.0275197150412587 CD2BP2 essential 0.0108346049467028 1 1 3.4630510871539 -2.22508159750585 0.400562736338744 126.66768293676 93.4671045785238 1.35521137097323 0.177360727300342 191.719665803488 370.869085521461 0.516947012539264 0.605944526699879 RSPO1 other 1 1 1 1.35521137097323 0.516947012539264 0.0145386710734358 35.9082399757375 39.5890261814344 0.907025088497301 0.365829208871602 -136.463386054719 65.3479065862179 -2.08825948960849 0.0384419989608128 RGS14 other 1 1 1 0.907025088497301 -2.08825948960849 2.80825319538419e-06 236.295542040953 83.5615771296194 2.82780136706151 0.00530617759011232 -484.584556156893 178.633802111191 -2.71272598147612 0.00742788306271334 TBC1D10B other 0.0245160503957039 1 1 2.82780136706151 -2.71272598147612 0.00809373514708549 612.342506060274 257.758308579526 2.37564604390376 0.0187648225371905 -338.917763868909 424.037817120109 -0.799263061419143 0.42538509526675 LMAN2 other 1 1 1 2.37564604390376 -0.799263061419143 3.85895653022893e-06 80.6631915468786 23.380754255336 3.44998243709223 0.000725812224862286 -76.0876693973979 38.4521171995467 -1.9787641081645 0.0496495014077083 RAB24 other 0.0332333336383316 1 1 3.44998243709223 -1.9787641081645 0.00696086872503076 956.672288760119 327.630461654327 2.91997357000789 0.0040337166472061 54.9934674016518 538.822861405278 0.102062238521628 0.918841790805493 PRELID1 essential 1 1 1 2.91997357000789 0.102062238521628 0.526584890101486 13.8851690273481 111.142267398143 0.12493148963398 0.900741785485261 -447.140126458209 439.090463590879 -1.01833258413653 0.310127492296516 CXCL10 other 1 1 1 0.12493148963398 -1.01833258413653 0.982396110582488 -0.417529777317461 4.92405150277001 -0.0847939500800471 0.932533925462163 -1.48606076298983 7.88466760736325 -0.188474750869909 0.850749466514515 SH3TC2 other 1 1 1 -0.0847939500800471 -0.188474750869909 0.41951057276752 -1.29280456633285 23.7997286471199 -0.054320138918445 0.956750969378586 -118.517606134568 94.025739528647 -1.26048044640435 0.20941503254438 CXCL11 other 1 1 1 -0.054320138918445 -1.26048044640435 0.00489246529445609 145.786097265452 47.0157487508022 3.10079284365252 0.00229827389391945 218.400095408078 194.691573279931 1.12177477293308 0.263715662638012 NMD3 essential 1 1 1 3.10079284365252 1.12177477293308 0.339607909851152 -3.3414034179182 2.33546554406373 -1.43072263532697 0.154509778810629 -1.16550146728811 3.73967849707366 -0.311658199548471 0.755716422666932 ADRB2 other 1 1 1 -1.43072263532697 -0.311658199548471 0.00266937542333611 188.133336343948 61.2198501543289 3.07307737391848 0.0025116239691666 405.970023689771 249.906515040152 1.62448755537463 0.106343649223606 B3GALNT1 other 1 1 1 3.07307737391848 1.62448755537463 0.519146724907376 21.2014756979111 20.467485601961 1.03586127334956 0.301933919089166 29.6161687767081 33.5883181878749 0.881740151770961 0.379328077685527 GPRIN1 other 1 1 1 1.03586127334956 0.881740151770961 0.0831288002089519 5.74342620462363 2.55419205697573 2.24862738451395 0.0259835122243684 0.355992592070255 9.99558426499174 0.0356149858410051 0.971636396842696 KCNAB1 other 1 1 1 2.24862738451395 0.0356149858410051 4.44071409881325e-10 67.5101389183134 21.3021229165494 3.16917422656806 0.00184433125194332 -107.121334100058 34.8634761760532 -3.07259475673389 0.00251010591270779 MRPL1 other 5.10293577072045e-06 1 1 3.16917422656806 -3.07259475673389 5.17656019951424e-07 43.0446455427911 29.5789991254931 1.45524347731199 0.147637267862971 -183.093061485262 51.6298476503249 -3.54626383415466 0.000517947566943932 PGM2 other 0.00484008378654581 1 1 1.45524347731199 -3.54626383415466 0.501628926361915 -3.64347826086949 12.0636526265449 -0.302021151773912 0.763035651097799 -21.1240683229813 18.4103493896172 -1.1474018160076 0.252961059721319 STK32A other 1 1 1 -0.302021151773912 -1.1474018160076 0.202072002381307 5.44800196324503 4.67292456672177 1.16586559133502 0.245494931866595 -31.9911234607787 25.8528281332006 -1.23743225677098 0.217834828018125 C22orf15 other 1 1 1 1.16586559133502 -1.23743225677098 1.67599405002055e-05 18.7828936896787 4.10927192728882 4.57085683839645 9.90797089539001e-06 2.16486998798997 7.31979160210129 0.295755686182173 0.767815082618168 KIAA1024 other 0.135118640312657 1 0.100674892268058 4.57085683839645 0.295755686182173 4.71997943914698e-07 154.672650320001 27.3151997460983 5.66251214553519 7.24054035864721e-08 43.3731823091563 107.010850408965 0.405315742687742 0.685815341978861 SLC33A1 other 0.00443064469952727 1 0.000847070816558137 5.66251214553519 0.405315742687742 1.80461111112713e-14 179.880501678478 30.067609909904 5.98253410289278 1.54735005595972e-08 -173.509371503171 50.8175799414765 -3.41435723037167 0.000822449040851009 SNUPN essential 2.39562125002127e-10 1 0.000186734204753219 5.98253410289278 -3.41435723037167 2.53196443395628e-06 1.81292550567342 7.08733929823859 0.255797758423106 0.798450584437097 -60.8102102387006 14.3863861536748 -4.22692742910753 4.05862243611083e-05 CRADD other 0.0222154559435324 0.584806906819209 1 0.255797758423106 -4.22692742910753 2.38867488073975e-13 855.402406666438 117.091538893638 7.30541604243035 1.51860776669254e-11 -142.660705808552 197.897626583148 -0.720881337849761 0.472104528078032 SIN3A essential 3.08688454837998e-09 1 2.01777413960438e-07 7.30541604243035 -0.720881337849761 0.117943720415973 -3.73366962561671 2.06350277905936 -1.809384345641 0.0723935673777835 -10.5095777730547 6.97021180150896 -1.50778456556794 0.133712947075834 RNASE2 other 1 1 1 -1.809384345641 -1.50778456556794 7.18636563144991e-11 625.031248267618 89.6728638447295 6.97012698679807 1.05273527782479e-10 -344.888797234399 432.069168327639 -0.798225891861993 0.426053857487579 PTK2 other 8.55824283049369e-07 1 1.371082425839e-06 6.97012698679807 -0.798225891861993 3.09664450116514e-08 18.7418616802305 12.3885238836982 1.51284058183013 0.132467124215403 -82.1200560499066 23.9843893246378 -3.42389605748891 0.000800093543176883 RSPH10B2 other 0.000319790477635324 1 1 1.51284058183013 -3.42389605748891 0.0861690333459116 -55.8441067682363 48.6498554297493 -1.14787816479487 0.252834182490529 -240.136938968139 107.758593691445 -2.22847135195308 0.0273265360987229 PTAFR other 1 1 1 -1.14787816479487 -2.22847135195308 5.76266393348947e-08 257.105082906649 54.1052618988135 4.75194230438218 4.67630944600422e-06 -134.89471364145 91.4438653433446 -1.47516416913218 0.142264324017367 PTPN9 other 0.000584103616298493 1 0.0488814626390821 4.75194230438218 -1.47516416913218 0.83760499417603 -2.7028321939449 18.251042430818 -0.148091935251928 0.88246910218887 -32.7203567530304 55.0281982859824 -0.59461072272405 0.552999552183465 RNASE6 other 1 1 1 -0.148091935251928 -0.59461072272405 0.529162703732349 7.01657486500641 9.67778981523889 0.725018315024566 0.469593307999913 -34.0958300977011 51.0125020385097 -0.668381842395456 0.504938037212186 KCNK9 other 1 1 1 0.725018315024566 -0.668381842395456 0.578765085737653 -65.031158154611 83.9448936645198 -0.774688671529012 0.439735020029892 -182.462604056453 181.56759907161 -1.00492932103205 0.316538541386016 CXCL8 other 1 1 1 -0.774688671529012 -1.00492932103205 0.112508690176318 34.9601200347469 17.5078164110352 1.99682925694329 0.0475831228267706 -2.76953855063312 53.1951844760428 -0.0520637079824475 0.958544538506892 SCN9A other 1 1 1 1.99682925694329 -0.0520637079824475 0.0144835728024014 16.5893303998791 7.61194571893619 2.17938106923305 0.0308532058476556 -9.39949280352014 16.4641665277946 -0.570906081862816 0.568911971034 RASSF6 other 1 1 1 2.17938106923305 -0.570906081862816 0.916720307830209 5.56750265206859 19.1918231616241 0.290097642375183 0.772147595426386 -22.8576022630988 105.149190234042 -0.217382580048617 0.828209605532333 COL22A1 other 1 1 1 0.290097642375183 -0.217382580048617 0.531728024635181 54.8309159238441 107.339220271528 0.510819025749792 0.610218901383888 542.32879556385 489.218218498114 1.10856214069211 0.269370084277643 SDC2 other 1 1 1 0.510819025749792 1.10856214069211 0.925170063967094 3.71549920857496 65.1243227081642 0.0570524046019626 0.954577407635681 -39.0009704076554 137.653411782027 -0.283327306622906 0.77730646285899 CD52 other 1 1 1 0.0570524046019626 -0.283327306622906 4.17719457102949e-21 237.011554556574 20.6029225005524 11.5037832399855 1.09813686249427e-21 112.722036639319 74.2349964938703 1.51844873662285 0.131274846502022 TM2D2 other 5.93746436326132e-17 1 1.57868155352176e-17 11.5037832399855 1.51844873662285 5.28436579542173e-15 209.279234539713 24.5463877668338 8.5258668822336 2.80773964889366e-14 -68.6827255711381 88.364778553579 -0.777263596371637 0.438373296776787 PLEKHA2 other 7.08422078534238e-11 1 3.88478857820927e-10 8.5258668822336 -0.777263596371637 0.000335699419877485 483.876087608763 205.125684657592 2.3589249118972 0.0195748695590238 -560.637713771373 454.901400737689 -1.23243787084897 0.219651708256212 CLIC4 other 1 1 1 2.3589249118972 -1.23243787084897 0.0972695744515092 -28.356756192068 23.8657067011593 -1.18818003368367 0.236603599727626 55.538757407689 49.023095899627 1.13291003737101 0.259024261447016 GPR183 other 1 1 1 -1.18818003368367 1.13291003737101 9.8680131454429e-11 450.610444470749 88.1693406296026 5.11073850902156 9.21509949420013e-07 -231.434106175835 181.068596283784 -1.27815706823681 0.203080490471694 CCDC8 other 1.16876747694626e-06 1 0.0100896124361997 5.11073850902156 -1.27815706823681 2.73312820854201e-09 28.4553531338119 12.2598546961216 2.32101879174911 0.0215888605766345 -86.316230924428 20.8387047620973 -4.14211112973898 5.63867062015931e-05 METTL15 other 3.01382047555927e-05 0.811066382003715 1 2.32101879174911 -4.14211112973898 0.188580806692039 76.1700693329609 42.8185774120196 1.77890238155318 0.0772285180386954 42.9709231986227 72.6957869653984 0.591106101087755 0.55531592670004 MUC15 other 1 1 1 1.77890238155318 0.591106101087755 0.129338460458215 -63.5281525249814 31.2032426053526 -2.03594713948363 0.0434584405137729 -47.597552493303 83.4289008888279 -0.570516355677854 0.569153660217438 ZEB2 other 1 1 1 -2.03594713948363 -0.570516355677854 0.00296969920936484 932.124843815077 421.662321345284 2.21059553256074 0.0285578773659054 -702.952016520893 644.440899365207 -1.09079361228209 0.277089821564947 HINT1 other 1 1 1 2.21059553256074 -1.09079361228209 2.51308448418546e-08 63.3551185674218 15.2642661451508 4.15055122630632 5.47129862169197e-05 -31.5614802571955 22.3168015464003 -1.41424747590168 0.159307788468116 DTWD2 other 0.000261134608751711 1 0.514958626273648 4.15055122630632 -1.41424747590168 0.0116046358051258 -44.9366125467495 54.8380311313556 -0.819442485801708 0.414131955042131 -252.840188374668 85.4071388821606 -2.96041047251941 0.00369255993710178 CLIC3 other 1 1 1 -0.819442485801708 -2.96041047251941 8.49618200108799e-06 77.5787368624815 50.0408999925515 1.55030658669266 0.12313398667774 -381.920474601747 107.08164220741 -3.56662885186233 0.000483042797983026 INO80E other 0.0707222189770565 1 1 1.55030658669266 -3.56662885186233 0.122586864713985 -51.076310047373 26.1461675154371 -1.95349127237163 0.0525975729180589 -4.34784205766607 43.7244147944625 -0.0994373984901613 0.920922013823029 BNC1 other 1 1 1 -1.95349127237163 -0.0994373984901613 7.53238391810532e-11 31.5781647790606 9.99494101597885 3.15941482081553 0.00192192862674264 -84.4889599130279 22.2169348975352 -3.80290802051193 0.000209588803364704 DFFB other 8.96127714736989e-07 1 1 3.15941482081553 -3.80290802051193 7.4433067561618e-05 68.875902201971 21.6724377886962 3.17804129251647 0.00179224120763437 -118.387643122795 62.0376232366597 -1.90832009587429 0.0582104939196004 CKAP2L other 0.555345117077232 1 1 3.17804129251647 -1.90832009587429 1.60245494850411e-10 135.673644434512 24.9673719390235 5.43403786212906 2.16226997903729e-07 -103.727497308169 41.9677017201856 -2.47160299603154 0.0145615447488222 C15orf40 other 1.88032063657473e-06 1 0.00246347418711718 5.43403786212906 -2.47160299603154 2.36039358338364e-07 93.4651768482214 21.6444317825098 4.31820884869557 2.83582496895281e-05 -74.1962253418116 36.3821654585727 -2.03935704229306 0.043158050733038 FAM103A1 other 0.00227494733566516 1 0.275301887985938 4.31820884869557 -2.03935704229306 1.48262227074734e-07 42.9823713338073 8.55805749332429 5.02244479747136 1.38839098291309e-06 -28.6834575527775 24.172690814847 -1.18660590053798 0.237198673668804 RGPD8 other 0.00145474897205729 1 0.0150390511269146 5.02244479747136 -1.18660590053798 0.00304954567269881 61.4079192716902 17.7550234703215 3.45862225270143 0.000706915562725536 46.5109868012138 32.8580040505244 1.41551467124101 0.158990549787548 HIC2 other 1 1 1 3.45862225270143 1.41551467124101 1.65497812998712e-05 141.602319036362 49.4940790088468 2.86099513057009 0.00481419263735124 -146.122550296715 108.784888559068 -1.3432247091688 0.181188243836157 LUZP1 other 0.133540185308661 1 1 2.86099513057009 -1.3432247091688 0.102124020901633 55.108069065144 33.2910603311475 1.65534135942148 0.100230905858081 -202.231822246682 160.849971889855 -1.25726986377818 0.210875894816612 HEXDC other 1 1 1 1.65534135942148 -1.25726986377818 0.000185906977802665 150.732357626499 60.9814159230685 2.47177529981686 0.014547398024675 -415.112626624745 172.028853272661 -2.41304071222752 0.0170104057558917 BUB1 other 1 1 1 2.47177529981686 -2.41304071222752 6.64433726167698e-07 463.755323621794 91.175961858573 5.08637709071987 1.06117231493851e-06 66.2830608661245 192.820005634965 0.34375614007401 0.731504737201496 SPNS1 other 0.00615464960549138 1 0.0115821494668939 5.08637709071987 0.34375614007401 0.0198415165129213 67.4933583106266 24.6101213800369 2.74250408067372 0.00691248098784971 100.595197547684 111.217289789363 0.904492437625516 0.367322143455963 LRRC45 other 1 1 1 2.74250408067372 0.904492437625516 0.378136016529891 11.6408449659276 11.8149412582051 0.985264734841013 0.326049562706306 -11.2068382219287 21.1945747904633 -0.52875975728333 0.597738334443161 CHRNA5 other 1 1 1 0.985264734841013 -0.52875975728333 0.0767442487632699 163.659443119891 71.5497839203802 2.28735062711034 0.0237076220922671 43.6729819482325 323.345542663362 0.135065977989067 0.892757948875378 CENPX other 1 1 1 2.28735062711034 0.135065977989067 0.0557690236026754 400.045631768953 274.78512664713 1.45584892694239 0.147921551733219 -422.339432697266 425.867042932812 -0.991716639514407 0.323236439112336 AGPAT2 other 1 1 1 1.45584892694239 -0.991716639514407 1.31683428916724e-08 246.999531675749 38.5236840321913 6.41162801224698 2.16114356492108e-09 -48.0349540190711 174.095026375512 -0.275912270551962 0.783031206509625 ASPSCR1 other 0.000139465919565702 1 2.69818774080397e-05 6.41162801224698 -0.275912270551962 4.33421442807304e-07 2972.1151226158 521.507898146992 5.69907978992503 7.08038049177624e-08 1847.68324250683 2356.78216047745 0.783985585724441 0.434401939670995 FASN other 0.00408369683413042 1 0.000828900144172245 5.69907978992503 0.783985585724441 3.8379133753292e-07 1054.47900543389 190.921503303973 5.52310235979557 1.40920310076839e-07 -502.656018442285 785.481952846018 -0.639933249415882 0.52317939369233 CNBP other 0.00362951467904882 1 0.00162481117518595 5.52310235979557 -0.639933249415882 0.120717933113609 -743.352465047827 555.552166616784 -1.33804259926609 0.182867811702256 -1793.96075545744 868.853381855035 -2.06474509154498 0.0406350097354752 MT1E other 1 1 1 -1.33804259926609 -2.06474509154498 3.82284337333641e-05 486.063181198909 109.514891463512 4.43832957055758 1.84894866108084e-05 -605.23893051771 494.916267663276 -1.22291177328908 0.223462513846534 DUS1L other 0.295123508421571 1 0.182934980527339 4.43832957055758 -1.22291177328908 6.46860503771314e-10 1048.0977520436 149.665232102164 7.00294742688234 1.02588573843289e-10 -209.567779291545 676.36242963031 -0.309845387784315 0.757149337537531 GPS1 essential 7.37291602198543e-06 1 1.33652394003037e-06 7.00294742688234 -0.309845387784315 2.30476163691678e-06 364.292276907357 68.1446481791298 5.34586774811357 3.66450671967791e-07 76.7690309945537 307.957159865138 0.249284773986657 0.803513866204213 RFNG other 0.0203187785910584 1 0.00411597394754223 5.34586774811357 0.249284773986657 0.705289740940008 122.71875 162.074609485997 0.75717442966045 0.450245646358929 -226.718749999996 732.442499260643 -0.309537950390448 0.757382647461273 DCXR other 1 1 1 0.75717442966045 -0.309537950390448 0.0985627643789836 19.7023152965659 49.8854456691173 0.394951173279044 0.693447543772669 -203.644224765869 112.96112370343 -1.80278150649882 0.0734571618316931 ZNF32 other 1 1 1 0.394951173279044 -1.80278150649882 0.35334355143571 4.22905268065942 13.5062463675441 0.313118283612979 0.754625742726025 -22.9449491601159 24.7614516738308 -0.926639902310952 0.355602059638106 LDB2 other 1 1 1 0.313118283612979 -0.926639902310952 0.0569539568893863 109.549429495913 46.3727925297191 2.3623642985422 0.0195657271425423 -79.0834894414151 209.566471675486 -0.377367089349464 0.706484767185311 RAC3 other 1 1 1 2.3623642985422 -0.377367089349464 0.606513552261043 22.9813625097834 23.3856533297638 0.982712015171034 0.327321134414315 23.8192179754762 40.0862392052807 0.594199367356426 0.553267972065638 NRG4 other 1 1 1 0.982712015171034 0.594199367356426 0.0028934858684763 84.1958086603987 120.408294723799 0.699252562736919 0.485455876305381 -987.778079261966 333.171670649498 -2.964772116838 0.00351476596081804 LIMS1 other 1 1 1 0.699252562736919 -2.964772116838 0.00136971005891218 14.485604047091 4.2411367547076 3.41550034457442 0.000817951828623675 1.0159816886251 7.26989406941805 0.13975192470809 0.889042230240508 TMEM266 other 1 1 1 3.41550034457442 0.13975192470809 0.00539859028090322 23.4158109115942 7.25816263107513 3.22613478118301 0.00154261056116512 -23.4359269609973 37.2118849207916 -0.629796824613492 0.529792095361034 NLGN1 other 1 1 1 3.22613478118301 -0.629796824613492 7.54669502838672e-08 85.4289017341037 29.5799324110126 2.88806953805947 0.00445002340873393 -141.767299752271 55.8835262397845 -2.53683525881988 0.0122079879173988 TAPT1 other 0.000758820185104285 1 1 2.88806953805947 -2.53683525881988 0.0253070961556912 502.871743523556 187.911062422559 2.67611569558763 0.00826512050601923 566.74161407685 338.775380547547 1.67291263361833 0.0964014405267845 LINGO1 other 1 1 1 2.67611569558763 1.67291263361833 0.00074548300275182 34.2982304739198 240.186846542558 0.142798121411043 0.886643845466374 -1981.85473594219 561.571317945444 -3.52912385766597 0.000555862607634078 HNRNPF other 1 1 1 0.142798121411043 -3.52912385766597 0.000275001835420036 48.9106900452488 21.1326783055027 2.31445770092062 0.021930214860199 -75.489585218703 40.4122729431976 -1.86798662190591 0.0636158082760591 BTD other 1 1 1 2.31445770092062 -1.86798662190591 0.372247936655297 23.6903571313356 28.0343341671042 0.845047968327855 0.399448087606506 -46.8483240313575 65.5459622896302 -0.714740044922176 0.475895566025773 CSGALNACT2 other 1 1 1 0.845047968327855 -0.714740044922176 0.0162430016534558 -87.1070379642044 132.087076763065 -0.659466770700475 0.510593989947001 -623.645751202399 233.83166670735 -2.66707140219343 0.00848042994873577 PCDH7 other 1 1 1 -0.659466770700475 -2.66707140219343 0.814686981952639 -35.4389800817491 84.8000496853389 -0.41791225610421 0.676604953396656 -122.056353171257 193.364936671643 -0.631222781504192 0.528849202514281 ROBO1 other 1 1 1 -0.41791225610421 -0.631222781504192 2.72862266268127e-07 61.7431615184221 16.0276295125507 3.85229527985239 0.000171289610891169 -45.5086434685522 25.4754691730005 -1.78637116197975 0.0760066462539699 AVEN other 0.00261402051084866 1 1 3.85229527985239 -1.78637116197975 0.724893941450789 5.76566493783667 7.19805716125364 0.801002938525219 0.424380240865978 3.4322406134452 29.2641451805829 0.117284840963765 0.906789169406172 P2RY1 other 1 1 1 0.801002938525219 0.117284840963765 7.25949110001061e-05 43.7292061920867 9.99009909823311 4.37725449588592 2.24134661330611e-05 0.656983511598667 40.6541635694091 0.0161603007887986 0.987127981539443 CTNND2 other 0.542501769903793 1 0.219786448900797 4.37725449588592 0.0161603007887986 0.00175605533360871 352.880512650628 102.313991537901 3.44899565881863 0.000728274847573919 -51.2795974988612 341.387514745122 -0.150209352375251 0.880798587326053 TRIM56 other 1 1 1 3.44899565881863 -0.150209352375251 0.431149171239594 -16.2666911822062 13.8296450919903 -1.17621899000339 0.241370709074797 -41.2870368513133 47.0880370207116 -0.876805224077473 0.381994511415146 MUC3A other 1 1 1 -1.17621899000339 -0.876805224077473 0.502064036038978 -15.8809070958303 26.5169267285891 -0.598896970918897 0.550144982478661 35.4016093635698 54.9398657848537 0.644370146483497 0.520319594659721 ITGAM other 1 1 1 -0.598896970918897 0.644370146483497 0.513454829024507 -5.85653278402828 7.57365068594142 -0.773277383243917 0.440567075631344 24.6509735824884 30.7220142085527 0.802387936388163 0.423589632034545 TM4SF4 other 1 1 1 -0.773277383243917 0.802387936388163 0.331387267428511 804.745351290656 557.496383794412 1.44349878256326 0.150937846741704 -627.612408074625 2271.64599168847 -0.276280903966086 0.782707620262967 TM4SF1 other 1 1 1 1.44349878256326 -0.276280903966086 2.95700640362272e-06 50.5694865653337 14.5211469766695 3.48247191813301 0.000645772471891851 -33.2826880868464 32.0533188097683 -1.03835388417574 0.300722422427587 OTUD3 other 0.0257348267307286 1 1 3.48247191813301 -1.03835388417574 6.66814623461277e-05 23.662760010216 5.70500130310061 4.14772210435001 5.53241932721763e-05 5.71490394165555 9.12120220531496 0.62655161162039 0.531880859358922 OTUD7A other 0.500110967595958 1 0.520434686111362 4.14772210435001 0.62655161162039 2.86045216052888e-06 417.830421548063 113.334333493756 3.68670647867782 0.000314299144085337 -175.935015603417 153.957678930501 -1.14274920761073 0.254916204563776 BRD3 other 0.0249460032919723 1 1 3.68670647867782 -1.14274920761073 1.84749294420081e-08 671.708995611555 148.434950984861 4.52527515355911 1.19419844347313e-05 -333.156175369559 236.7950700811 -1.40693881530328 0.161447491056787 KLF13 other 0.000193931334352759 1 0.120399087070961 4.52527515355911 -1.40693881530328 0.0433375456548086 86.6424070951308 36.4308795494556 2.37826833078548 0.0186367760674788 -12.6655753975255 157.736483483227 -0.080295789013658 0.936107630288553 ZFPM2 other 1 1 1 2.37826833078548 -0.080295789013658 9.36418424827422e-08 48.0205607267768 10.6685141163752 4.50114797646183 1.32051071851382e-05 -35.2573443139534 22.7564960359602 -1.54933098040398 0.123341565203252 ZNF764 other 0.000933796453237905 1 0.132489571975433 4.50114797646183 -1.54933098040398 7.08444780335413e-08 91.2216633516216 20.889550874138 4.3668561330611 2.29522598363255e-05 -80.8864983629639 44.5584995693688 -1.81528774857061 0.0714127010287841 ZNF747 other 0.000713899805143995 1 0.224909194136153 4.3668561330611 -1.81528774857061 0.000195654067793576 242.108477388787 66.847135283051 3.62182278064163 0.000395844467646396 -53.9188773172722 142.588419764016 -0.378143452368066 0.705841401266971 ZNF768 other 1 1 1 3.62182278064163 -0.378143452368066 0.0363905984173156 61.6055160001058 27.6896596404819 2.22485638321243 0.0279142671303899 1.04012598925387 61.1320010912103 0.0170144273160955 0.986452674341417 TAS1R3 other 1 1 1 2.22485638321243 0.0170144273160955 3.59293193664331e-08 198.983128233422 48.6946446267278 4.08634521842681 7.03088435805901e-05 -298.891357017775 116.891422539644 -2.55699991089085 0.0115245938313846 MAP3K2 other 0.000369209685809467 1 0.653801936455907 4.08634521842681 -2.55699991089085 1.38617330550107e-05 68.6842328154362 27.1811859649558 2.5269034582961 0.0127759053297236 -137.049630766788 60.009415487389 -2.28380212761094 0.0240982721992672 PUSL1 other 0.112820645334732 1 1 2.5269034582961 -2.28380212761094 1.89342642270092e-06 260.812111888978 103.048681189481 2.53096021102307 0.0123784440716919 -515.017836475283 211.267214299885 -2.43775560813821 0.0159170098530716 SF3B5 essential 0.0168439214563474 1 1 2.53096021102307 -2.43775560813821 1.38452651932772e-05 23.7741170138564 8.76446925645308 2.71255638170583 0.00743652920162608 -50.692783248481 19.326069699442 -2.62302599736275 0.00959134456868997 ZNF35 other 0.112755839734049 1 1 2.71255638170583 -2.62302599736275 2.97877513331436e-05 12.5783093254666 3.45801040148703 3.63744114825613 0.000376545068365647 -0.181674407495762 5.39869629673008 -0.033651533168443 0.973199177557624 TIGD4 other 0.233506182700513 1 1 3.63744114825613 -0.033651533168443 0.0482757731529643 10.7924016282225 20.8425086686436 0.517807227517628 0.60533104095534 -83.1853389790859 47.0793535717573 -1.766917611821 0.0792101501116119 IFFO2 other 1 1 1 0.517807227517628 -1.766917611821 1.27134078229154e-08 511.534335930424 80.3152929559032 6.36907763271535 2.297151792768e-09 331.246693241531 427.685393961232 0.774510184164851 0.439873108331598 NLGN2 other 0.000134787549738549 1 2.86500771594025e-05 6.36907763271535 0.774510184164851 0.657069547058899 -13.890813316477 22.5789303641134 -0.615211309502723 0.539353661288189 -47.4660317460316 54.1838575425261 -0.876017948865637 0.38243034859863 MYO7B other 1 1 1 -0.615211309502723 -0.876017948865637 6.63895465670151e-09 1286.96159533074 209.425131289054 6.14521087994182 7.51500156311049e-09 -1279.65038910506 1315.68470012431 -0.972611742755807 0.332388626735741 CHD3 other 7.15546532899289e-05 1 9.1961074127783e-05 6.14521087994182 -0.972611742755807 0.0295721486027817 -9.81310981218681 12.4625786889948 -0.787406046298619 0.432270302953213 -48.3562771722467 19.4567596983082 -2.48532016235218 0.0140265797095721 TMEM154 other 1 1 1 -0.787406046298619 -2.48532016235218 0.155578753812694 15.3854322464853 12.8332799929267 1.19886983335245 0.23238494999714 -24.131422720265 27.8414717920962 -0.866743787845138 0.387405117867984 MYRIP other 1 1 1 1.19886983335245 -0.866743787845138 0.571377004189199 79.9877101285493 129.168884058646 0.619249060727601 0.536685477269647 -441.818745585533 602.365102850415 -0.733473342819545 0.464407016498774 ALCAM other 1 1 1 0.619249060727601 -0.733473342819545 4.38233194470062e-05 380.912617322087 110.380150558942 3.45091590646712 0.000724670186830481 -851.852342481485 403.985377157396 -2.10862172407195 0.0366278993226785 YWHAG other 0.335949566880749 1 1 3.45091590646712 -2.10862172407195 2.18685125397988e-10 592.142936288088 86.647676697357 6.83391590932466 1.72307683522919e-10 7.47590027700812 298.528911997265 0.025042466496768 0.980052892147232 UBE2E3 other 2.54964987701514e-06 1 2.22948911710305e-06 6.83391590932466 0.025042466496768 3.70355551366452e-23 305.003241013552 25.3152772621158 12.0481888408936 1.21207065567161e-23 42.0181202121401 161.552333254224 0.26008983817039 0.795160909195327 CNTROB other 5.30571362887579e-19 1 1.74829071374073e-19 12.0481888408936 0.26008983817039 1.82909965330533e-17 823.956867702833 83.1351983807009 9.91104711063163 5.32381344511138e-18 100.225016732351 529.858774398929 0.18915420782839 0.850236464394445 TRAPPC1 essential 2.53622957927316e-13 1 7.56513890550327e-14 9.91104711063163 0.18915420782839 0.0649226898863352 13.9890373930019 5.98167265311496 2.33864977310604 0.0207290845060975 6.04635831205862 38.0744121080096 0.158803720853425 0.874046017957235 KCNAB3 other 1 1 1 2.33864977310604 0.158803720853425 0.831024524566063 -4.74181184833449 10.9975463695946 -0.431169980009758 0.666951658844177 -10.3132714374047 17.7573525104502 -0.580788798968502 0.56223731381701 FAM153A other 1 1 1 -0.431169980009758 -0.580788798968502 0.150589702250018 22.12414216547 15.1502746353567 1.4603129446801 0.14632363948606 -50.8513570154949 55.9950302897544 -0.908140539479258 0.365280349331849 GPR37L1 other 1 1 1 1.4603129446801 -0.908140539479258 6.1720823903938e-06 137.021164425428 33.0514868958662 4.14568835759596 5.59373660471992e-05 -56.3218909757725 53.2957662059423 -1.05677983422054 0.292277822625039 SIMC1 other 0.0519936220566774 1 0.525811240843672 4.14568835759596 -1.05677983422054 2.80162605392684e-11 122.300313669938 31.5987387591721 3.87041756957588 0.000158979534428963 -117.915840331883 47.8077796128125 -2.46645716004518 0.0147206869682107 TMEM192 other 3.38968736264608e-07 1 1 3.87041756957588 -2.46645716004518 0.000766876713384587 12.7076906341782 3.42606136571232 3.70912522506324 0.00029418670052205 -4.60696907066972 13.6121294288691 -0.3384458761389 0.735510120891601 SPDYE5 other 1 1 1 3.70912522506324 -0.3384458761389 2.21235122004239e-07 114.016 21.0057257835169 5.42785339459529 2.38096580297457e-07 56.8043000000001 36.4044540393526 1.56036676002875 0.120883624630045 ZNF778 other 0.00213779498392697 1 0.0027064438282412 5.42785339459529 1.56036676002875 0.00380610212905562 -32.140643985419 27.0603972162904 -1.18773733173696 0.236933848047169 -147.638629880078 44.3668980872097 -3.327675276957 0.0011171354113462 NIPA1 other 1 1 1 -1.18773733173696 -3.327675276957 5.28390362924771e-06 172.130167369711 100.683322382452 1.70961946126355 0.0893374229436877 -680.706599537351 194.454147934009 -3.50060210476127 0.000606417358093412 UBE2E1 other 0.0448075027760206 1 1 1.70961946126355 -3.50060210476127 1.37058056334504e-18 418.564104112567 49.6162043023963 8.4360363715358 2.38192240887345e-14 -149.384460759363 129.011218083096 -1.15791838088952 0.248713536990469 SIK2 other 1.9193610209084e-14 1 3.29920072853061e-10 8.4360363715358 -1.15791838088952 0.006926524666542 411.773570220944 168.269080708854 2.44711368533244 0.0155104379289149 -16.2181499312425 270.805974420464 -0.0598884495290404 0.952321131207143 RNF150 other 1 1 1 2.44711368533244 -0.0598884495290404 0.161155211852752 145.447921454982 80.9592992928838 1.79655608096112 0.0745622371450125 319.950929349455 284.978863764449 1.12271810310084 0.263478945809866 HOXD4 other 1 1 1 1.79655608096112 1.12271810310084 3.31687074376409e-09 89.290583118843 13.3717954289937 6.67753134521011 4.58360723937154e-10 96.2195497174703 71.6459326352301 1.34298691046917 0.181332136871939 CHRNB1 other 3.64225576372734e-05 1 5.84501595164659e-06 6.67753134521011 1.34298691046917 2.67340347385624e-17 344.644165518649 46.5599878617947 7.40215325102028 7.81380539431534e-12 -44.6326496249809 75.2053891403684 -0.593476745950686 0.553721645963935 USP38 other 3.70025774816442e-13 1 1.04376812457264e-07 7.40215325102028 -0.593476745950686 0.00521068087823783 149.107606423304 45.2227318305563 3.29718264217188 0.00120942252111624 -7.3826069976345 196.983855418664 -0.0374782338478639 0.970151611638497 SLC16A5 other 1 1 1 3.29718264217188 -0.0374782338478639 0.0075926647151905 23.4792651598558 7.44125266179975 3.15528395916301 0.0019426650245389 39.3450029451584 28.7013997774528 1.37083916639031 0.172500398202474 NANP other 1 1 1 3.15528395916301 1.37083916639031 0.341476390077646 28.5974941470066 28.2515404623977 1.01224548038608 0.31300844960692 -21.9368882423245 45.3781419694846 -0.483424117652864 0.629481248652543 ADRA1B other 1 1 1 1.01224548038608 -0.483424117652864 1.26111361155567e-15 26.7737722632089 5.0050993495599 5.34929886368053 3.21086081210576e-07 -128.758942544154 19.6277276273031 -6.56005346054649 8.07690516018791e-10 ADPRM other 1.70943950046371e-11 1.18132814872908e-05 0.00361799796308077 5.34929886368053 -6.56005346054649 0.563171126823511 19.0276039159043 27.9851037566915 0.679919005530027 0.497576544521374 -20.0874658963249 45.7263361604592 -0.439297516114905 0.661061759750557 FABP6 other 1 1 1 0.679919005530027 -0.439297516114905 2.54521434938888e-05 69.6612724793538 23.0285316848173 3.02499844248782 0.00291425454641169 -69.4821510013823 36.9888495649744 -1.87846207218017 0.0622081448471148 PWWP2A other 0.2015809764716 1 1 3.02499844248782 -1.87846207218017 8.74577860182282e-08 13.495179781136 3.47642648641422 3.88191144955165 0.000153356600601836 -12.0071651902033 5.20060298887205 -2.30880250153597 0.0222843054674887 USP50 other 0.000874315486824227 1 1 3.88191144955165 -2.30880250153597 5.38273140748619e-08 243.442694889003 52.7447074062346 4.6154904797183 8.24551345204737e-06 -37.0131193019685 82.6019535401614 -0.448090120338045 0.654722023086753 USP47 other 0.000546347237859849 1 0.0843103750471843 4.6154904797183 -0.448090120338045 3.25089428259068e-11 499.896019251981 107.169852555955 4.66452092010649 6.66699459642292e-06 -766.11109996992 236.231944734238 -3.24304615462485 0.00145009748833482 PDCD6IP other 3.92187886251739e-07 1 0.0687369488915187 4.66452092010649 -3.24304615462485 2.30448222093142e-11 115.370262390671 15.6279185079614 7.38231789037656 1.51962891716226e-11 6.86394557823126 47.483892020847 0.144553137624392 0.885282516606331 ZNF212 other 2.79695007154446e-07 1 2.01897897934178e-07 7.38231789037656 0.144553137624392 3.11806622152164e-11 18.7466600631462 3.01215304624194 6.22367448643923 4.74255911206011e-09 -7.58766173466227 5.95897473807363 -1.27331664727197 0.204902009451418 MRAP other 3.76412954262092e-07 1 5.84710112925891e-05 6.22367448643923 -1.27331664727197 1.64672550326444e-09 353.074205544287 52.6515206429179 6.70586910374028 5.00953630002244e-10 107.360998422357 161.598354056583 0.66436938079682 0.507587109514482 ZNF282 other 1.83791033419345e-05 1 6.3856559216386e-06 6.70586910374028 0.66436938079682 0.00957071325557617 186.989972926902 118.041029827619 1.5841099759971 0.115220107478795 -438.635432333969 260.195020983643 -1.68579487292166 0.093860386911097 GLB1 other 1 1 1 1.5841099759971 -1.68579487292166 8.88781847074043e-05 95.1394773169987 32.2253210769012 2.95232053980042 0.00364164287021518 -110.39853624024 56.5115152916782 -1.95355823800565 0.05254238551703 GON7 other 0.655921003140644 1 1 2.95232053980042 -1.95355823800565 0.0434137060332938 108.82842084716 73.6160924548997 1.47832379060099 0.141417919849727 -133.765621272258 116.366776420324 -1.1495172882429 0.252172275519943 FAXDC2 other 1 1 1 1.47832379060099 -1.1495172882429 0.000954307226302641 483.332036498546 223.472987742523 2.16282084640772 0.0320979803188869 -917.89396035964 492.596166094597 -1.86338023626308 0.0643130765767046 CRTAP other 1 1 1 2.16282084640772 -1.86338023626308 0.00243621835099882 5.4061835534654 15.054523212781 0.3591069260085 0.720016749982687 -110.667400247952 38.7117576865328 -2.85875420961449 0.00485467958221616 HSPB2 other 1 1 1 0.3591069260085 -2.85875420961449 3.70603607465415e-11 266.017662053897 35.6640558930761 7.45898511519386 6.99701117186032e-12 148.01611434814 189.355028723615 0.781685679782956 0.435656515581194 ELP5 essential 4.46392045192092e-07 1 9.35990184459754e-08 7.45898511519386 0.781685679782956 4.35762667136994e-05 10.1223102376416 24.1658931928331 0.418867622929144 0.675896502414623 -210.531996390254 53.2683008237062 -3.95229420001623 0.000117625891824867 CMTM8 other 0.334186389427361 1 1 0.418867622929144 -3.95229420001623 2.69251246657838e-06 1278.38225790659 287.750830431485 4.44267095941877 1.74437299901493e-05 -2449.13964228593 1482.23241788715 -1.65233172121351 0.100615934662679 GABARAP other 0.0235567915700942 1 0.17295458285233 4.44267095941877 -1.65233172121351 0.0456995109218169 35.4084768211921 20.5354761587408 1.7242588653646 0.0867212050926092 -121.793377483443 98.7158689304417 -1.2337770897733 0.219215656315554 STX8 other 1 1 1 1.7242588653646 -1.2337770897733 0.412283313488602 118.688304937915 101.389411468798 1.1706183438538 0.243548835495552 -49.3006971659588 231.447480751283 -0.213010299381647 0.831598829282299 CDK1 essential 1 1 1 1.1706183438538 -0.213010299381647 0.221085232317586 -2798.4234372815 1605.25742553058 -1.74328639928674 0.0832665090299042 -1438.68378548455 5407.49917487744 -0.26605344521706 0.790551619311684 UBB other 1 1 1 -1.74328639928674 -0.26605344521706 3.96688932462098e-14 344.786958745465 44.6098163773957 7.72894817204792 1.27344400647467e-12 -133.884479525272 124.182876298485 -1.07812351844282 0.282653613447024 NFRKB other 5.23074026344523e-10 1 1.72615335077642e-08 7.72894817204792 -1.07812351844282 0.506804261411065 34.7713621101271 34.5223534843064 1.00721296785093 0.315433143454853 104.144252765415 107.866838521008 0.965489062193405 0.335833513217049 FABP4 other 1 1 1 1.00721296785093 0.965489062193405 2.95009385843436e-05 50.9284020111325 12.923703528289 3.94069717706337 0.000122601683073247 -38.8052545470315 35.9764465962929 -1.07862944282635 0.282428643211375 PRDM10 essential 0.231493865071344 1 1 3.94069717706337 -1.07862944282635 0.428538153232901 -1110.39755982155 1584.88095789457 -0.700618904082649 0.484604967978265 -3070.41851426254 2360.24479895239 -1.30088985499528 0.19525196905592 FOS og 1 1 1 -0.700618904082649 -1.30088985499528 6.26195617878598e-11 1797.8153078203 424.072096660674 4.23940957676081 3.86192327901956e-05 -2151.06262290123 634.885781163981 -3.38810962021788 0.000894968042376727 TMED10 other 7.47677567747047e-07 1 0.36923848470706 4.23940957676081 -3.38810962021788 4.91590892282745e-06 32.7638468228027 13.3765999848792 2.44934040487408 0.0154480048134223 -72.708489519297 25.3534422802419 -2.86779557251519 0.00472112575283775 SETMAR other 0.0418098053886475 1 1 2.44934040487408 -2.86779557251519 7.03647332027315e-09 259.901437707137 52.880191449387 4.91491105806407 2.23946649762701e-06 -23.8803855669139 85.5021499938359 -0.279295731962711 0.780390205120489 SMAD1 other 7.57265258727796e-05 1 0.0239331784601399 4.91491105806407 -0.279295731962711 0.442045847159329 -20.7444826718134 16.2604385813243 -1.27576403109072 0.203997971491342 -18.7538570349681 62.810179205795 -0.298579900138827 0.765671095642607 CST5 other 1 1 1 -1.27576403109072 -0.298579900138827 0.575489758755119 -10.79055131325 10.2612893642332 -1.05157850346386 0.294672928736469 -11.2539709178964 39.6369028194758 -0.28392659661508 0.776855579927601 CST2 other 1 1 1 -1.05157850346386 -0.28392659661508 9.91796949137487e-08 1621.23767238573 322.84680588028 5.02169339407041 1.38499256910569e-06 -198.443801040375 578.818436485378 -0.342842916762185 0.732178173825935 EMX2 other 0.000987135503476541 1 0.0150050094936911 5.02169339407041 -0.342842916762185 0.674040785112134 -0.513384241000207 67.5251405823239 -0.0076028607504239 0.99394388852315 -220.273777556672 260.833443062446 -0.844499750378775 0.399726203035227 CST1 other 1 1 1 -0.0076028607504239 -0.844499750378775 0.130217637905576 13.108502275548 6.50784001510312 2.01426314186064 0.0457814101115815 3.25983772353222 25.7659360362539 0.126517341304639 0.899492989198944 TCAF2 other 1 1 1 2.01426314186064 0.126517341304639 0.163180654336318 11.7649674991448 21.5651544692219 0.545554520183751 0.586166681898964 -110.13405991887 70.1830137862894 -1.56924095984583 0.118657627748252 SEMA3E other 1 1 1 0.545554520183751 -1.56924095984583 1.47398596713326e-08 1162.26793254768 191.441564086672 6.07113684059477 9.50355934303074e-09 -445.008219946827 717.237998385736 -0.620447077467162 0.5358805809544 LRRN2 other 0.000155593958690587 1 0.000115791367035486 6.07113684059477 -0.620447077467162 0.000726910338978319 144.98745309525 53.6584097181833 2.70204528715501 0.00765942589502655 -256.629830122221 160.317612624188 -1.60075880573275 0.111466548017578 SLC30A1 other 1 1 1 2.70204528715501 -1.60075880573275 6.09746278294522e-05 47.9365393334854 36.8935977631091 1.29931864171345 0.195763892525048 -148.604522783948 58.5049100933197 -2.54003505939779 0.0120681618463692 DCLK2 other 0.459260896811434 1 1 1.29931864171345 -2.54003505939779 0.00051438097104909 633.183665338644 212.890240858675 2.97422588646972 0.0034076749657714 -2268.3591500664 865.462763629767 -2.62097833135288 0.00964083506582689 GPRC5C other 1 1 1 2.97422588646972 -2.62097833135288 1.75657398188313e-09 47.6802091212594 9.10208597526836 5.2383826356742 5.24496668801244e-07 -59.2987420523895 25.3051038505068 -2.34335106477747 0.0203896856807656 TMEM182 other 1.95770170280875e-05 1 0.00583587541211714 5.2383826356742 -2.34335106477747 0.00109140908548635 2880.83313575377 1821.37615050666 1.58167939936646 0.115801374799637 -14536.725683074 5379.99241604813 -2.70199743027741 0.00767599805533644 KRT8 other 1 1 1 1.58167939936646 -2.70199743027741 4.99064254302542e-07 -1.32182419463009 4.30755338722462 -0.30686194129372 0.759360316244665 -99.3615550056659 17.6893313603606 -5.61703283077853 8.77357082292122e-08 ADORA2B other 0.00467024329176319 0.00128225737576994 1 -0.30686194129372 -5.61703283077853 7.35265248069999e-05 202.320483314154 53.4362003896128 3.78620638890864 0.000220725828255222 -58.5939503534439 103.975794444929 -0.563534529033854 0.573912437462504 MGMT other 0.549022560733868 1 1 3.78620638890864 -0.563534529033854 0.0130483633574347 94.5252252931635 68.8910665094447 1.3720969943208 0.172181822389966 -379.156757852269 183.967395181123 -2.06099976291437 0.0411147313547623 METTL7B other 1 1 1 1.3720969943208 -2.06099976291437 0.324216200266558 0.595055915244254 11.6059772785579 0.0512715044120947 0.959175617319701 -44.1037374926428 31.8370318111222 -1.38529677497245 0.167964985051588 KRT86 other 1 1 1 0.0512715044120947 -1.38529677497245 2.79927551350388e-08 230.492439516129 64.1249095307035 3.59442907916723 0.000446611124071391 -263.118388282733 94.7997842311341 -2.77551674211848 0.00624891051866765 HARS essential 0.000289976950443867 1 1 3.59442907916723 -2.77551674211848 6.76276469589029e-14 123.052038123296 16.9968395899095 7.23970109103976 2.04391224385462e-11 -3.33263189274975 31.9912919528409 -0.104173094905403 0.917168416494808 NFXL1 other 8.864631963373e-10 1 2.70838811433175e-07 7.23970109103976 -0.104173094905403 0.000258158559581532 39.0730072640336 10.0154149108764 3.90128692737448 0.000144787713513159 -72.5271062544074 75.3221397251557 -0.962892272033865 0.337172195217409 DENND5B other 1 1 1 3.90128692737448 -0.962892272033865 0.724436268945435 -68.57729232716 234.901756287942 -0.291940313307398 0.770749530174982 181.824120240151 346.491605512962 0.52475764880644 0.600553048483332 CD14 other 1 1 1 -0.291940313307398 0.52475764880644 6.47738072923965e-07 89.8848511193219 22.0826128773415 4.07039020330564 7.54478896534243e-05 -41.8093023255814 32.2518197537829 -1.29633932735462 0.196836318732821 DNAJC18 other 0.00600647515022393 1 0.699401937087243 4.07039020330564 -1.29633932735462 0.1424832716853 -15.3047471132419 10.3536213355929 -1.47820232333864 0.141369851627085 -55.9784108119578 32.1355921615571 -1.741944275697 0.0834891797207977 KRT6C other 1 1 1 -1.47820232333864 -1.741944275697 2.15322452056435e-15 94.6747355671727 14.7421318525309 6.4220518792144 1.58515565990649e-09 -48.0002751406196 22.1199099349015 -2.17000319087572 0.0315394317675808 RIOX1 other 2.90749907011804e-11 1 1.98730965082477e-05 6.4220518792144 -2.17000319087572 3.22616499237747e-06 22.2648430465427 6.40765811381286 3.47472393986608 0.000667675911273837 -15.6036544850498 9.35843216010931 -1.66733638905468 0.0975202113892816 SPATA24 other 0.0279837551438821 1 1 3.47472393986608 -1.66733638905468 1.17502743206329e-09 432.111842105263 69.5894990769176 6.20944032989299 5.02998527830912e-09 -163.901691729323 319.765722460889 -0.512568046593457 0.609012516069128 RALGAPB other 1.32155335284159e-05 1 6.19694186287683e-05 6.20944032989299 -0.512568046593457 1.12290348704151e-09 74.7303041081274 23.9307848374695 3.12276862692439 0.00218632357629444 -312.645385025787 65.7215378007691 -4.75712217771825 4.91763436649191e-06 PYM1 other 1.26438932640874e-05 0.0715417447637244 1 3.12276862692439 -4.75712217771825 0.350404145866018 48.0090041316425 82.0553960395987 0.585080402372004 0.559372754275093 174.026366528945 120.486474674303 1.44436433217397 0.150722084285486 MZB1 other 1 1 1 0.585080402372004 1.44436433217397 0.358873529824436 -24.0713606759373 30.0166797225582 -0.801932821965222 0.423827531325181 -127.807158364138 91.6017696011892 -1.39524770013262 0.164949971436139 KRT4 other 1 1 1 -0.801932821965222 -1.39524770013262 0.221024837101762 -42.3549793417864 24.3049404709115 -1.74264896441435 0.0834443487929221 -34.6681673552737 35.6882878622109 -0.971415818240545 0.332905086607393 SLC23A1 other 1 1 1 -1.74264896441435 -0.971415818240545 0.177924731743053 -139.721491006335 157.111903914675 -0.889311933246102 0.375240741042418 -828.003218124701 449.174124765415 -1.84339028557607 0.067219517860666 NPAS2 other 1 1 1 -0.889311933246102 -1.84339028557607 2.77893085883126e-15 568.646117985809 64.6474169332864 8.79611506477714 2.88403711883081e-15 -144.60540225551 286.592135565666 -0.504568633644091 0.614592527307397 LONRF2 other 3.74349775993159e-11 1 4.03073027727794e-11 8.79611506477714 -0.504568633644091 3.10240228681494e-11 119.078638681222 29.7732451601738 3.9995182937098 9.80005988705084e-05 -101.630917451281 44.7999972001813 -2.26854740631256 0.0246763291958842 NUDT9 other 3.74553028087168e-07 1 0.897783486252727 3.9995182937098 -2.26854740631256 6.23431814746222e-07 349.050286428372 140.52426533161 2.48391468622648 0.0142868680067672 -1477.66315903308 389.271898330276 -3.79596668901943 0.000225980432022502 PA2G4 other 0.00578544724084494 1 1 2.48391468622648 -3.79596668901943 0.359122109946838 8.97316801866573 7.8233729207784 1.1469692304752 0.253196564792308 -1.64992267831465 14.47047302692 -0.114019954651464 0.90937244184609 COX7B2 other 1 1 1 1.1469692304752 -0.114019954651464 0.000541401116283264 204.4620452496 62.5501607510245 3.26876930122439 0.00132890278746242 46.2311269330673 94.3170508002539 0.490167223644178 0.624704243224357 ELOVL6 other 1 1 1 3.26876930122439 0.490167223644178 0.332091403746244 120.530905935314 88.0912946871509 1.36824990895377 0.173226814559138 -5.31960238400718 341.399035370243 -0.0155817733293772 0.987588215184383 PFKFB3 other 1 1 1 1.36824990895377 -0.0155817733293772 0.0107932381583974 10.7803604705748 4.22894034714782 2.54918716880118 0.011756068286503 -0.662659857461886 8.67793578469186 -0.0763614612856248 0.939228751246896 TMC7 other 1 1 1 2.54918716880118 -0.0763614612856248 0.000127951434643029 1131.97278688675 345.860958062929 3.27291288738287 0.00130915415860024 -472.060782139286 701.925374124301 -0.67252274891503 0.502239551482921 ARL6IP1 other 0.925088872469099 1 1 3.27291288738287 -0.67252274891503 0.719499454638234 -23.426801175154 29.2813818252402 -0.800057911029337 0.424995126759893 -17.4751566174221 74.7627595850022 -0.233741460513553 0.815517666126822 SERPINB9 other 1 1 1 -0.800057911029337 -0.233741460513553 0.000878570659728843 79.9810165710214 34.4374039592008 2.32250423596906 0.021523801774201 -178.84344214926 88.3638509315517 -2.02394350476866 0.0447162232091589 SMAGP other 1 1 1 2.32250423596906 -2.02394350476866 0.825555947520176 -6.44399912155484 14.0593906150814 -0.458341282206243 0.647466712427589 -25.9305753815746 48.6644481081227 -0.532844332765514 0.595044082619596 IRX1 other 1 1 1 -0.458341282206243 -0.532844332765514 0.000167790173294712 966.623241872264 268.890817726941 3.59485403794589 0.000446887629145725 -105.143618860964 677.404736045956 -0.155215358361225 0.876871956017358 CDH2 other 1 1 1 3.59485403794589 -0.155215358361225 0.110496906730739 -181.622713738835 92.4273279529535 -1.96503261277101 0.0515428153033048 -245.74747101141 138.812410690215 -1.77035662581958 0.079011749688294 EMB other 1 1 1 -1.96503261277101 -1.77035662581958 0.9161460337045 11.8493735473419 28.4888462994772 0.415930270491837 0.678043840300142 6.35264080511487 116.243230623912 0.0546495548258454 0.956488954369143 SIX2 other 1 1 1 0.415930270491837 0.0546495548258454 0.000853408827083126 219.321401355831 62.4130672756735 3.51403016914881 0.0005847639935013 74.3228858429409 165.235855543899 0.449798777621818 0.65350921800304 DLGAP1 other 1 1 1 3.51403016914881 0.449798777621818 0.0553290100093594 239.561252675024 155.077141965237 1.54478764335704 0.124791734213308 -474.664898197832 402.970678590914 -1.17791423400237 0.240950069589538 STAT2 other 1 1 1 1.54478764335704 -1.17791423400237 0.000658760593492401 133.031595044009 40.8207944082339 3.25891734770295 0.00138365165165157 -37.1771489807468 66.9900881680978 -0.554964920891855 0.579745272310581 NUDCD2 other 1 1 1 3.25891734770295 -0.554964920891855 2.64184551681476e-37 484.338359148112 31.9368206383021 15.1655158362019 1.43842684660164e-32 -180.549056147144 102.474635614427 -1.76189019911699 0.0800341351302537 IRF2BP1 other 3.8449419651722e-33 1 2.09089726422015e-28 15.1655158362019 -1.76189019911699 7.22776464241108e-09 773.38214314921 137.085783316556 5.64159261769201 7.79569916109319e-08 41.8594608961142 228.250048583368 0.183392998844533 0.854729349246946 HSPA4 other 7.77056976705616e-05 1 0.000910849489982128 5.64159261769201 0.183392998844533 0.0173827360707168 9.87628267182961 4.28927621003103 2.30255226947909 0.0226172929141431 -9.33591481122945 13.7628607947722 -0.678341149448787 0.498554012536316 FOXA3 other 1 1 1 2.30255226947909 -0.678341149448787 0.000288099436380127 168.238203572632 40.0335343437178 4.20243194438397 5.75002748010499e-05 159.525109538254 147.540915012697 1.0812262451031 0.282197072396791 COMMD5 other 1 1 0.539640079007854 4.20243194438397 1.0812262451031 0.184479683740441 -11.1112808689131 36.2871099040431 -0.306204624680652 0.75986786095352 85.5834328731352 57.4246123037049 1.49036152687466 0.138201413799534 SGCD other 1 1 1 -0.306204624680652 1.49036152687466 0.00489086081399971 252.523842115434 77.2788080675344 3.26769846003256 0.00135576609388065 108.686904148415 221.955786666384 0.489678173211045 0.625106794552535 GTSF1 other 1 1 1 3.26769846003256 0.489678173211045 0.469756108986186 3.98603204374643 11.8729265442205 0.335724476092775 0.73753857339666 -37.8234622039652 37.1922118141621 -1.01697264989125 0.310771898643222 DPY19L2P2 other 1 1 1 0.335724476092775 -1.01697264989125 6.38668351718158e-06 104.724721941355 21.4651729604449 4.87882031672129 4.03645641199285e-06 -16.6366700370744 79.1084602298379 -0.210302033293772 0.833859853327329 ZNF16 other 0.0537120083794971 1 0.0423787558695129 4.87882031672129 -0.210302033293772 2.12276540510957e-10 268.22008611922 45.7410037176804 5.86388719790038 2.69170987315654e-08 -297.658686549816 143.284732077152 -2.07739291014998 0.0394364686488286 ARMC10 other 2.47641812160082e-06 1 0.00032155166144728 5.86388719790038 -2.07739291014998 1.22823226198128e-15 154.214158573863 29.7876504138327 5.1771172425956 6.94357893401637e-07 -260.378954202396 64.9771857847139 -4.00723655630606 9.53994354662664e-05 RNF34 other 1.66511447756803e-11 1 0.00766223935368706 5.1771172425956 -4.00723655630606 0.000403747082523676 73.7380018184647 19.9979655980279 3.68727516091619 0.000313033177340498 -88.7352986951286 85.1430313029407 -1.04219097367354 0.298945952947488 ACYP2 other 1 1 1 3.68727516091619 -1.04219097367354 2.50472853891346e-08 405.50980999487 111.822942985372 3.62635608730058 0.000394833604387439 -355.883170559368 180.095077132607 -1.97608494482792 0.0500042971846422 TRABD other 0.000260316437049276 1 1 3.62635608730058 -1.97608494482792 0.012778301627966 13.1858300799336 6.52979667327303 2.019332414117 0.0451650111292086 -18.1999292888289 18.0778944969277 -1.00675049806945 0.315613701573379 TMEM133 other 1 1 1 2.019332414117 -1.00675049806945 9.17034699487067e-06 243.359540636043 59.8968921626753 4.06297441902491 8.00951516421819e-05 -242.645027763755 160.314537958167 -1.51355598097455 0.132376807742996 ATF7 other 0.0760369793873695 1 0.740559772083613 4.06297441902491 -1.51355598097455 0.00358169889875512 106.765419568199 32.943631760721 3.24085153524257 0.00146244288694161 -0.624259493273825 102.227634718723 -0.00610656301489766 0.995135652850432 RASA4B other 1 1 1 3.24085153524257 -0.00610656301489766 1.16223127709624e-13 88.6100409586761 25.9282625688463 3.41750785357843 0.000813673643471158 -139.900451387697 44.9901244074817 -3.10958134102053 0.00224255719245661 SOCS6 other 1.5131088996516e-09 1 1 3.41750785357843 -3.10958134102053 0.00155326703733206 14.0886917960089 3.97148115892464 3.54746534913027 0.000513130516519491 6.25424981522544 5.9594417841043 1.04946906804384 0.295575079787605 CAVIN4 other 1 1 1 3.54746534913027 1.04946906804384 6.60074905522058e-10 15.4338334184934 4.17116107276373 3.70012884884046 0.000297647687433847 -76.4103719419386 17.6127185212846 -4.33836331680418 2.55920966108671e-05 ZNF296 other 7.51891324880176e-06 0.370010532799916 1 3.70012884884046 -4.33836331680418 0.0784456224209225 0.177079819844843 63.2500305751732 0.00279967959279296 0.997769805175778 -588.148866093928 258.628428804321 -2.27410756355375 0.024340797127029 HOXB9 other 1 1 1 0.00279967959279296 -2.27410756355375 0.000139616095603417 43.8374260260607 18.4014745629025 2.38227789170967 0.0185595798929391 -108.724422570144 51.400158399617 -2.11525462090705 0.0361921440354065 POLH other 1 1 1 2.38227789170967 -2.11525462090705 0.496705018182273 -9.79615585645108 18.6928106388893 -0.524060080942068 0.60100008376917 51.2510428891236 60.305379128459 0.849858563693822 0.396740357777372 KCNS3 other 1 1 1 -0.524060080942068 0.849858563693822 1.36208559186027e-09 564.028452555094 86.3196923984126 6.53418051991885 8.84256388453203e-10 76.8610464976865 379.330552569458 0.202622873314726 0.839697259354216 KIF5B other 1.52744278271211e-05 1 1.11840748011561e-05 6.53418051991885 0.202622873314726 0.190949986215066 12.3889403586087 11.4722700905549 1.07990312822294 0.281895865561707 -37.8775668151574 35.3751190497082 -1.070740334808 0.285983457186151 GPR37 other 1 1 1 1.07990312822294 -1.070740334808 1.08123163442464e-14 513.475496971468 63.9159515440477 8.03360482895426 2.90992227444935e-13 -38.8214687435185 135.145485180392 -0.287256867602345 0.774322946483165 CDCA4 other 1.44106552236116e-10 1 3.98019168699182e-09 8.03360482895426 -0.287256867602345 0.490446336514844 -86.8690062543428 84.7945804484891 -1.02446413196317 0.307265408299135 -177.901431549687 161.147590712119 -1.10396581645144 0.271375790714243 HTRA3 other 1 1 1 -1.02446413196317 -1.10396581645144 0.00841273532650542 44.5276399411286 14.5864135174491 3.05267911730749 0.00267246557810225 -14.704654655217 65.1236128867273 -0.225796051591816 0.821659434462116 FOXN2 other 1 1 1 3.05267911730749 -0.225796051591816 0.0221448780280096 17.8845374220374 6.63528841516416 2.6953669988428 0.00779738566330857 7.65925155925155 9.17086753638296 0.835171975700829 0.404890004275604 CELP other 1 1 1 2.6953669988428 0.835171975700829 8.92935101223724e-09 197.680152451982 31.7584986491489 6.22448040242229 4.32144802419902e-09 231.10653816098 127.063764700804 1.8188233183958 0.0708685758772466 USP32 other 9.5490479724865e-05 1 5.33612402028095e-05 6.22448040242229 1.8188233183958 0.0274335474816855 166.456618156618 65.252488968776 2.55096197535499 0.0116987932780318 54.1787479787479 90.1877801399428 0.600732692330154 0.548884290083383 CEL other 1 1 1 2.55096197535499 0.600732692330154 7.40013384258873e-12 124.086924219911 15.9940370748533 7.75832415788298 1.02574993346023e-12 43.7643016344727 64.5978941846286 0.677488054167664 0.499093477383515 PPM1D other 9.13768526882857e-08 1 1.39286583464565e-08 7.75832415788298 0.677488054167664 0.0697936207933504 78.6717029949474 70.9102372235864 1.10945479912708 0.268963513344325 -203.294100417389 169.032915731971 -1.20268942612186 0.230942376003013 GPR27 other 1 1 1 1.10945479912708 -1.20268942612186 4.20442320742633e-14 261.803785735194 36.7058245526023 7.1324861633338 3.67490704571992e-11 -75.6291345497116 92.6585674753767 -0.816213077865783 0.415647236163469 KBTBD2 other 5.54100934506716e-10 1 4.84609992119085e-07 7.1324861633338 -0.816213077865783 8.44649448795011e-09 30.5399399732852 23.8282825658188 1.28166769421705 0.201873152978009 -228.709691799724 48.043993700455 -4.76042215028344 4.39749047184384e-06 TRIAP1 essential 9.04535094714578e-05 0.0639966788367433 1 1.28166769421705 -4.76042215028344 0.0111067665340106 -12.5301560596055 91.0634850009528 -0.137598029105457 0.89073555125942 -473.685684365743 174.864168311075 -2.70887791902043 0.00750558024691146 LSM3 essential 1 1 1 -0.137598029105457 -2.70887791902043 9.24488853841725e-10 294.51258912656 48.3947602767877 6.08562967234742 8.83577684351347e-09 78.8729303784452 92.2077198601621 0.855383155532533 0.393667919878521 KIAA0232 other 1.04541199592422e-05 1 0.000107787641714021 6.08562967234742 0.855383155532533 2.16679041972355e-15 275.70258584487 34.5041291146947 7.99042297020196 3.39606006744879e-13 1395.65885150552 320.486044509443 4.35481942323513 2.46430339060218e-05 MTSS1 other 2.92538374566877e-11 0.356461485450605 4.64139529418226e-09 7.99042297020196 4.35481942323513 3.7541816877284e-07 333.040898512168 105.431878477122 3.15882542664206 0.00190254786467257 -518.818674792726 202.45499876469 -2.56263702036689 0.0113343463920214 TMEM43 other 0.00355295754926616 1 1 3.15882542664206 -2.56263702036689 2.9724688445107e-27 356.361959377084 26.2915589615976 13.554234646093 1.01067254052141e-27 488.902859859703 243.658990120434 2.00650449884099 0.0466240002456491 RNF139 other 4.29789270227802e-23 1 1.46466664572362e-23 13.554234646093 2.00650449884099 0.14354906804531 1996.50853001771 1384.56716003318 1.44197304951958 0.151327454687721 -936.671147034373 2835.14777419915 -0.33037824538051 0.741560309989444 RPS9 other 1 1 1 1.44197304951958 -0.33037824538051 0.0919773346179935 20.0245982737596 13.0330498290701 1.53644761098779 0.126494064319525 -9.72488207496 24.8712549032294 -0.391008902156251 0.696334605184537 CYTL1 other 1 1 1 1.53644761098779 -0.391008902156251 5.51843000205131e-09 236.828858161558 56.8513082859471 4.16575915844137 5.12245637613417e-05 -219.711195171457 116.42835566157 -1.88709351706474 0.0610054265262923 TSEN34 essential 5.97259679122014e-05 1 0.484174576672202 4.16575915844137 -1.88709351706474 0.0124461633432672 51.7512633352049 21.8785272920454 2.36539062453352 0.0192901026747906 -43.5909601347562 65.3536811522391 -0.667000838609421 0.505796331911048 GSTA4 other 1 1 1 2.36539062453352 -0.667000838609421 6.00841840482194e-11 105.772280540473 17.9517032551437 5.89204706857918 2.31907058397516e-08 -59.0026718294966 48.8816251575198 -1.20705217225004 0.229262803787445 MSANTD4 other 7.17585410087885e-07 1 0.000277871037371904 5.89204706857918 -1.20705217225004 0.020079362298818 9.42249150546923 162.848424919662 0.0578605013227339 0.953933793282219 -776.73526386662 335.465193553621 -2.31539748025294 0.021894054434095 NDUFA3 other 1 1 1 0.0578605013227339 -2.31539748025294 0.258673563995106 15.150637326918 9.4488480731615 1.60343749942936 0.110860850077119 11.0386466523012 19.4644783901694 0.567117516895614 0.571449487612302 OSCAR other 1 1 1 1.60343749942936 0.567117516895614 1.49653279317307e-05 152.453227820573 33.8617276594986 4.50222827829659 1.34191379399878e-05 21.1086311402957 100.152893206102 0.210764067462903 0.833357426331516 PAQR8 other 0.121293982886677 1 0.134513438710438 4.50222827829659 0.210764067462903 7.90290179497728e-07 38.8730862207897 11.7017738020349 3.32198236595803 0.00111191360810427 -23.0747507050765 17.6109711397029 -1.31024862411226 0.192025433354211 NUDT6 other 0.00726848177365122 1 1 3.32198236595803 -1.31024862411226 0.00108431107258617 195.395789972865 55.7575106022299 3.50438511085626 0.000597515576226281 337.567497431305 226.840059422846 1.48812999912884 0.138735260795733 TANC2 other 1 1 1 3.50438511085626 1.48812999912884 1.15652169714901e-06 68.0156249999999 13.5361976517522 5.02472162049107 1.40769948297526e-06 8.59548611111112 40.238575281495 0.213613082744111 0.831136951250014 PKHD1 other 0.0104954344016272 1 0.0152383469032072 5.02472162049107 0.213613082744111 5.8747906642243e-06 13.9226496799297 8.80636385729207 1.58097597436893 0.115921994823699 -48.5214949165307 14.3294896875265 -3.38612860434015 0.000898336698764696 DNAJC24 other 0.0495832332060531 1 1 1.58097597436893 -3.38612860434015 4.16290011507634e-09 93.8690435378812 22.3928163798183 4.1919266404775 4.63349589956611e-05 -138.953774114127 57.0277461121019 -2.43659943777156 0.0159585914955216 ZNF160 other 4.53839370545623e-05 1 0.43985776574581 4.1919266404775 -2.43659943777156 6.08263497856978e-08 31.9265570622825 9.71544415086945 3.28616546670441 0.00125614756679905 -69.2303837608049 24.1830985551662 -2.86275902994305 0.00478100744535727 ZNF415 other 0.000615380180781905 1 1 3.28616546670441 -2.86275902994305 0.50429390633533 -42.9039273035789 86.8040835721079 -0.494261623854812 0.621821180312787 -155.854062939561 137.607921130298 -1.13259514175777 0.259133300144447 CAVIN3 other 1 1 1 -0.494261623854812 -1.13259514175777 0.0811258694121235 11.4644692582729 11.5820986607925 0.98984386112011 0.323803133242809 145.830910320001 65.664690687926 2.22084211152487 0.0278212383851372 HAS2 other 1 1 1 0.98984386112011 2.22084211152487 0.341606125558313 13.2776003649635 21.7448266591035 0.610609620997132 0.542369987445879 -52.3514834000471 59.0215872953586 -0.886988740883354 0.376486235277963 PDGFD other 1 1 1 0.610609620997132 -0.886988740883354 0.244798136898196 -6.66637389865302 15.2802042107886 -0.436275183674981 0.66325207664742 -79.0691363959951 46.98315027386 -1.68292538782753 0.0944290425553749 S1PR1 other 1 1 1 -0.436275183674981 -1.68292538782753 3.7447231629419e-05 48.0653456691191 15.2024822771365 3.16167746772552 0.00189167137304943 101.323731818071 22.713113368022 4.46102347028857 1.57181041624942e-05 PYGO1 other 0.289616889421926 0.227786765522866 1 3.16167746772552 4.46102347028857 1.58349122943231e-08 46.7907579751295 13.957614243961 3.35234640800984 0.00100981910727063 -107.723227316229 38.8150270430114 -2.7752969796172 0.00620338001194213 LRRC8E other 0.000166852470845283 1 1 3.35234640800984 -2.7752969796172 0.862341420815602 -8.48306122550162 16.4115373915204 -0.516896194617616 0.605984887581221 -19.5896989047928 53.0062588159948 -0.369573317234032 0.712218211927179 PKIA other 1 1 1 -0.516896194617616 -0.369573317234032 0.000144132480220293 5.5938397701882 9.2950526951319 0.601808290244322 0.54819834099432 -46.0170145073774 17.8213866461991 -2.58212312099698 0.0107637024657988 XKR6 other 1 1 1 0.601808290244322 -2.58212312099698 1.06728571208084e-06 101.858923405396 19.5009801341921 5.22327199476508 6.23450634189209e-07 -38.5763681569048 87.5676484109319 -0.440532192618398 0.66023115280605 TSNARE1 other 0.00971763640849602 1 0.0069040923230113 5.22327199476508 -0.440532192618398 0.0669270713881507 32.2415407847555 14.5119856403139 2.22171807386505 0.0277418414959859 52.6585505421407 28.1429053941346 1.87111280106551 0.0632022099517395 FPR1 other 1 1 1 2.22171807386505 1.87111280106551 0.00415131529915581 78.1241651487553 24.1032244164578 3.24123294870921 0.00146061432917222 -41.2120405399093 95.8863492315508 -0.429800914000684 0.667945175287382 FEZ2 other 1 1 1 3.24123294870921 -0.429800914000684 0.01230959462981 53.3360995850621 18.8045140930408 2.83634553496922 0.00518558074278996 47.4105876054077 36.0538586856526 1.3149934385324 0.19049253094026 SOX7 other 1 1 1 2.83634553496922 1.3149934385324 0.00404893262273535 202.1484375 59.9987629841839 3.36921008776944 0.000954045378949841 179.3955078125 179.317941342578 1.00043256391045 0.318680820658617 C11orf24 other 1 1 1 3.36921008776944 1.00043256391045 0.000142532613580414 27.7527276616986 8.94820173337093 3.10148658788046 0.00229321706316475 -91.0348630546518 36.8055490664055 -2.47340048888836 0.0144767145473151 FAM86JP other 1 1 1 3.10148658788046 -2.47340048888836 0.143320926068444 18.1429795175378 10.2430800606851 1.77124257645647 0.0785511429852289 -43.9000989195335 66.8889802208685 -0.656312875074109 0.512628378589267 ALK og 1 1 1 1.77124257645647 -0.656312875074109 2.13347558570099e-05 37.2374094758302 13.4470785578136 2.76918211756805 0.00631060778631117 -29.8075170276582 18.3680495560664 -1.62279162720429 0.106679302979755 KYAT1 other 0.170208682227225 1 1 2.76918211756805 -1.62279162720429 0.171676641929255 -59.1462664587662 78.7764051737211 -0.750811950968495 0.453889677646661 -202.880226380226 108.879664550762 -1.86334360247445 0.0642818307784325 OBP2B other 1 1 1 -0.750811950968495 -1.86334360247445 5.4745739132943e-11 78.1147484872926 11.1611942559438 6.99878047957933 8.68267336629933e-11 -61.4472167077894 45.3571845364235 -1.35474054079448 0.177592885451432 TRMT61B other 6.55032768725663e-07 1 1.13387031490503e-06 6.99878047957933 -1.35474054079448 7.97774166978181e-19 492.195803538469 53.6516500585603 9.17391735391627 2.69244154450005e-16 -13.5879266299737 176.851239702091 -0.0768325212357164 0.938855865199012 INSR other 1.11903782402029e-14 1 3.78988071803828e-12 9.17391735391627 -0.0768325212357164 3.19934005521951e-05 201.766748960564 43.1141818566357 4.67982321064292 6.59555441910741e-06 145.275588517269 205.613432199459 0.706547169429777 0.480997574014928 MFN1 other 0.249932445113748 1 0.0680331438330929 4.67982321064292 0.706547169429777 0.527831840838671 4.42827233900011 6.05516145125874 0.731321926697687 0.465715904994724 20.3871649245152 19.5993972208854 1.04019346588834 0.299912697494226 GIMAP8 other 1 1 1 0.731321926697687 1.04019346588834 0.00299400337985766 54.3348911317697 31.0421512522084 1.75035843006867 0.0820224518209732 -71.3437404741464 59.1558291454537 -1.20603060602405 0.229631625772229 NRTN other 1 1 1 1.75035843006867 -1.20603060602405 2.11140198061381e-05 43.9629230892333 9.20307333067106 4.77698280885345 4.33703393213886e-06 -30.6589826217893 44.2357796089833 -0.693081096180414 0.489374984463096 KCNMB3 other 0.1685532201124 1 0.0454396218716617 4.77698280885345 -0.693081096180414 0.00504641776125701 -5.88825066087768 28.0300537463205 -0.210069189098527 0.833887784044505 -148.580447025055 54.2822763962944 -2.7371815791277 0.00691665340404531 FUT3 other 1 1 1 -0.210069189098527 -2.7371815791277 0.00753611573188065 6.98168735855569 2.20053610124523 3.17272111764262 0.00182548550024609 6.23263671350576 9.95260402681016 0.626231757710484 0.532096102026658 KCNG3 other 1 1 1 3.17272111764262 0.626231757710484 0.00310554008035926 305.847585513079 88.3038709746316 3.46358072570731 0.000708937434812791 220.569709926224 273.129532172569 0.807564484776633 0.420721135791393 ATP6V0E2 other 1 1 1 3.46358072570731 0.807564484776633 6.19439490048358e-08 134.000835421888 22.2597291613634 6.01987717148309 1.27078529715383e-08 51.8869743803953 94.79642509551 0.547351593988041 0.584945282350423 PRKCE other 0.00062650110023491 1 0.000153917515191271 6.01987717148309 0.547351593988041 3.36291286116405e-05 162.515173797185 55.8916816287991 2.90768087595787 0.00416888465538889 -242.061342258981 114.455931234127 -2.11488683591092 0.0360184806906743 JAGN1 other 0.262038170141902 1 1 2.90768087595787 -2.11488683591092 2.05684170500203e-12 631.242670474651 113.028664808114 5.58480162130816 1.03278617546737e-07 -685.956212404588 233.970931320783 -2.93180100849415 0.00388422742637125 TADA3 essential 2.58647844404005e-08 1 0.00119927130695271 5.58480162130816 -2.93180100849415 1.2833259902221e-08 166.341113002889 26.3045607901091 6.32366053667146 2.70398179399941e-09 4.08392860558987 117.100894115991 0.0348752982325194 0.972224934797608 SOCS5 other 0.00013601972170364 1 3.36348295355587e-05 6.32366053667146 0.0348752982325194 0.00208682235789632 -119.365547982814 375.12227797228 -0.318204369593946 0.750758243260351 -1605.24041474208 518.701534910559 -3.09472848392259 0.0023378802327573 C9orf16 other 1 1 1 -0.318204369593946 -3.09472848392259 2.28226025477177e-13 95.3511803425578 14.8155646380386 6.43587893354708 1.39792700867309e-09 -16.1465876325373 25.7362343902252 -0.627387339877114 0.53131098143874 MORN4 other 2.95073428339443e-09 1 1.75607590829514e-05 6.43587893354708 -0.627387339877114 4.38077163548714e-09 244.690080269982 49.6032002103536 4.93294947165342 2.58966308988975e-06 -291.801404084144 161.978234481188 -1.80148527373925 0.0740961962367584 ZNF672 other 4.77153646537259e-05 1 0.0275488359502471 4.93294947165342 -1.80148527373925 2.13652508955641e-07 168.78489437459 40.104300725497 4.20864823276378 4.96097538902143e-05 -230.648445414457 130.446596777344 -1.76814459796253 0.0795570084083454 ZNF692 other 0.00206858359170851 1 0.469506710816988 4.20864823276378 -1.76814459796253 1.74591341936065e-06 49.2194211728865 9.96674642760861 4.93836394157126 2.03012726746249e-06 13.9523736989084 13.8188658123326 1.00966127672045 0.314241350983164 NAIF1 other 0.0155840231812132 1 0.0217731149435352 4.93836394157126 1.00966127672045 0.100496535373733 11.3606992589706 11.3098415541396 1.00449676545755 0.316835940531693 -72.0037264584641 43.3357624000491 -1.66153131895477 0.0987975611993709 RBKS other 1 1 1 1.00449676545755 -1.66153131895477 0.00579454809280859 4.8747984255028 1.54944915181215 3.14614933946138 0.00198397208700293 2.65694331017858 3.92388202560756 0.677121099166376 0.499338464552185 OPRPN other 1 1 1 3.14614933946138 0.677121099166376 0.399181277197375 -0.540209723546235 1.47297936783061 -0.366746293494829 0.714311689232756 3.71330028598666 3.73158173397645 0.995100885015236 0.321248189691847 SMR3B other 1 1 1 -0.366746293494829 0.995100885015236 1.38530888450055e-05 64.8687937884807 19.1810886221312 3.38191408560799 0.00090864826390708 -140.228139880501 67.3715045050499 -2.08141618493899 0.0390190036634136 TMEM126A other 0.112790614176574 1 1 3.38191408560799 -2.08141618493899 5.98973376472591e-05 99.8404026770999 31.4369001227017 3.17589845968946 0.00179844737288934 -207.945944921295 110.418720228304 -1.88324900425709 0.0615161197245697 TMEM126B other 0.451566081229277 1 1 3.17589845968946 -1.88324900425709 1.23695830974636e-12 809.358738610169 240.52984329195 3.36489945502432 0.000968021306339613 -1684.34913522091 424.816284610312 -3.96488834406614 0.000112424398843763 TRIM8 other 1.56636030763182e-08 1 1 3.36489945502432 -3.96488834406614 0.463941406704613 59.5260539835276 47.9358876389726 1.24178474448718 0.216334764243818 62.5855397279793 71.060870972758 0.880731390865898 0.37993080143867 NETO2 other 1 1 1 1.24178474448718 0.880731390865898 0.0362176286149368 37.9515583899189 56.7082142017661 0.669242700094353 0.504404866275932 -384.572161558695 172.466660456505 -2.22983480135096 0.0272953390720573 CDC42BPG other 1 1 1 0.669242700094353 -2.22983480135096 0.0284738919141307 234.945341931445 485.023808661418 0.484399606237585 0.628818377047331 -5506.20430638481 2428.13144461252 -2.26767143047459 0.0247969035015594 JUNB other 1 1 1 0.484399606237585 -2.26767143047459 0.392753029744935 -66.0253138161333 48.397868783231 -1.36421944759291 0.174476066563316 -90.7936067855946 134.671256270352 -0.67418697426663 0.501196678251022 TMEM37 other 1 1 1 -1.36421944759291 -0.67418697426663 4.59944266895807e-09 330.765314764503 70.2919210825037 4.70559503383432 5.5679861596379e-06 -279.618661769114 164.474414732335 -1.70007391255451 0.0911227385135981 UGT2B7 other 5.00419362382638e-05 1 0.057801264323201 4.70559503383432 -1.70007391255451 0.283176122475824 -46.0489039834793 123.317119448896 -0.37341858283158 0.70934715676804 -278.849680276679 191.727046248948 -1.45440972326151 0.1478547477797 LRG1 other 1 1 1 -0.37341858283158 -1.45440972326151 0.357775457045356 25.2375479116938 21.8038915392633 1.15747906130644 0.249090728135996 45.6669803004941 32.2896466960964 1.41429173042067 0.159544863972057 SHCBP1 other 1 1 1 1.15747906130644 1.41429173042067 0.112109450149592 -62.0792493143367 95.1706888246613 -0.652293790041901 0.515190452321746 -422.814526815339 211.983913903491 -1.99455948816868 0.0478672722314428 SOSTDC1 other 1 1 1 -0.652293790041901 -1.99455948816868 0.709818261213813 -0.94377865171154 1.93326876592428 -0.488177675213374 0.626109463572462 5.5058641472552 8.36908146163902 0.657881533653626 0.511583877174475 NPTX1 other 1 1 1 -0.488177675213374 0.657881533653626 5.40102150442454e-12 143.307978700746 29.057875874211 4.93181192324976 2.11344912400125e-06 -115.608911608094 42.0794538530162 -2.74739572457182 0.00673373952915608 FAM98B essential 6.69834686978731e-08 1 0.0226392670163014 4.93181192324976 -2.74739572457182 1.33382523810437e-16 75.8835356120302 10.4145077581744 7.28632954855389 1.68609525595315e-11 -103.71881290417 40.5897787888668 -2.55529386951522 0.0116051749793701 ZNF439 other 1.83120866939349e-12 1 2.23812284275221e-07 7.28632954855389 -2.55529386951522 5.71692813692399e-11 179.460661157025 32.9473867936094 5.44688603928472 2.05247064821795e-07 -275.238690400509 128.347786115406 -2.14447555918902 0.0336057130961875 ZNF440 other 6.83630266613371e-07 1 0.00234145851548704 5.44688603928472 -2.14447555918902 0.00159465017947744 599.730204072305 163.782244579472 3.66175348012952 0.000341219103636362 -46.2548732832069 710.402073146742 -0.0651108365693809 0.948168061068526 GAA other 1 1 1 3.66175348012952 -0.0651108365693809 1.80394868804043e-09 577.560701754386 85.7241713756183 6.73743114090521 2.84432699156712e-10 281.402339181286 348.678445174459 0.807054015170018 0.420848588102597 CANT1 other 2.00923804873943e-05 1 3.65154699177386e-06 6.73743114090521 0.807054015170018 0.963039653053465 -2.42971755688832 22.829143627436 -0.106430516910336 0.915382988000671 18.6644343242694 83.353590826987 0.223918779492179 0.823125194226157 KCNK3 other 1 1 1 -0.106430516910336 0.223918779492179 5.74730257259557e-11 181.865334114485 48.6010282250256 3.74200589486373 0.000255079713927538 -255.207420937151 84.4252301254716 -3.02288096292857 0.00292223017802533 ZDHHC16 other 6.87204968605253e-07 1 1 3.74200589486373 -3.02288096292857 0.618563336737053 -39.8509016818476 48.5128333356437 -0.821450716063784 0.412659469694918 -88.4562742355916 97.5942393141704 -0.906367782127361 0.36615717333562 CHST11 other 1 1 1 -0.821450716063784 -0.906367782127361 4.92912997952279e-10 145.10270531068 35.0772641608313 4.13665970770627 5.71049026586985e-05 -133.967118126156 60.9329927185625 -2.19859737966464 0.0293604029455423 EXOSC1 essential 5.65174043452083e-06 1 0.536386350673155 4.13665970770627 -2.19859737966464 0.00329530911126382 256.572168039425 173.594851631767 1.47799410885566 0.14140003323377 -502.729707872396 301.552988339093 -1.66713555266474 0.0974684198492155 PGAM1 essential 1 1 1 1.47799410885566 -1.66713555266474 1.63920953226237e-06 511.933605904227 97.9975119108955 5.22394493412959 6.1660468692359e-07 102.116671093572 388.212370647396 0.263043320652763 0.792901170723886 CHD7 other 0.0146627292660869 1 0.00683074672173953 5.22394493412959 0.263043320652763 0.000182462297058517 2.82910354304981 21.3861466053506 0.132286736608361 0.894930181066701 -110.052458634867 39.4629467420365 -2.78875420414659 0.0059590251066398 ESCO2 other 1 1 1 0.132286736608361 -2.78875420414659 0.00136108906458693 1655.56428791139 1310.10963934288 1.26368376981165 0.208216704646622 -18722.4463242081 5610.83980516552 -3.33683494349127 0.00105791547290537 KRT19 other 1 1 1 1.26368376981165 -3.33683494349127 4.83516490344452e-06 16.067892545306 3.22832479493015 4.9771610869326 1.68989649317139e-06 1.86155708899758 10.8632760696859 0.171362402746284 0.86416089382725 LURAP1 other 0.0411569236581198 1 0.0182001852314558 4.9771610869326 0.171362402746284 0.474765887832565 9.33767328855222 16.5077031085784 0.565655514103584 0.57268415171718 -47.6709446905816 56.9777177416324 -0.836659427229908 0.4044470643051 TPPP other 1 1 1 0.565655514103584 -0.836659427229908 0.822193534484693 14.9454905847374 39.7151186130648 0.376317410262521 0.707202265052027 -46.4383624304338 128.359967934554 -0.361782284443317 0.718013887872131 KCND3 other 1 1 1 0.376317410262521 -0.361782284443317 0.00120099920114124 -13.4398831700472 22.2936752597315 -0.602856326445347 0.54747410186346 -357.849769253177 95.6403736707775 -3.74161826766802 0.000255956570145002 KRT13 other 1 1 1 -0.602856326445347 -3.74161826766802 0.489951857750578 9.75499025129075 9.14624935109042 1.06655634204066 0.287841429004624 2.95661531509668 18.62327807735 0.158759124082058 0.874066659504961 PDE7B other 1 1 1 1.06655634204066 0.158759124082058 0.00278862283492512 117.862636732635 43.2009870544588 2.72823944008636 0.00724152465747662 -197.201206228358 156.00114173434 -1.26410104462043 0.208438394079403 MRPL36 other 1 1 1 2.72823944008636 -1.26410104462043 9.83616659485838e-10 209.111722228098 47.1928248385078 4.43100668255546 1.79260392967529e-05 -175.458424279721 96.7623260231938 -1.81329275029688 0.0717725356221747 ZNF581 other 1.11099501688925e-05 1 0.177557419234338 4.43100668255546 -1.81329275029688 1.96631726114157e-05 21.9446757439937 17.2049590488131 1.27548549704381 0.204083353762795 -77.1378698727618 32.6074052151772 -2.3656549597776 0.0192598371148534 NAT1 other 0.157423359926994 1 1 1.27548549704381 -2.3656549597776 0.00015385815875112 36.7354792828275 12.7060589181313 2.8911781001115 0.00439325638852586 -33.7798019580536 24.633523439103 -1.37129396213097 0.172278195606289 KSR2 other 1 1 1 2.8911781001115 -1.37129396213097 1.10407615597015e-09 83.3760764014562 20.0313982178492 4.1622694279605 5.29099035532908e-05 -86.8963069442832 39.8903401772352 -2.17837969188023 0.0309394812241319 ZNF524 other 1.24341056685358e-05 1 0.499257849928852 4.1622694279605 -2.17837969188023 0.276535600960171 74.3636981345744 50.4099931981388 1.47517770617989 0.14221965033871 29.3758281166438 75.2059879317184 0.390604909589313 0.696632620639527 MCC other 1 1 1 1.47517770617989 0.390604909589313 4.19547630897211e-11 161.402536655573 23.9507873264401 6.73892404686817 3.00498141966323e-10 20.3850017555212 34.304110696425 0.594243702625576 0.55322109598675 ZBTB26 other 5.04212342812269e-07 1 3.8538886707181e-06 6.73892404686817 0.594243702625576 0.000363051822497058 112.254473734847 30.861213510776 3.6373966207016 0.000382020811424838 73.6816432557247 56.9667652724427 1.29341455326353 0.197924437002076 DSEL other 1 1 1 3.6373966207016 1.29341455326353 1.00193232687729e-16 211.054270519639 31.8418035328847 6.62821345222082 7.18206495068435e-10 -300.901015112266 90.0101529001716 -3.34296749218934 0.00106897722253375 POLR1C essential 1.37825810885241e-12 1 9.10326732499241e-06 6.62821345222082 -3.34296749218934 0.0125233291295179 11.6449008092816 5.3911430888545 2.16000588694371 0.0324872198839219 -12.7057580749123 15.2341173499304 -0.834033097097702 0.405693343690759 DLK2 other 1 1 1 2.16000588694371 -0.834033097097702 3.7675510332916e-24 228.571492697629 22.2923460038911 10.253361968172 5.02628208687303e-19 -141.17873575196 79.0542556459737 -1.78584612046942 0.0761445151677092 ZNF562 other 5.41284056953004e-20 1 7.17451505080256e-15 10.253361968172 -1.78584612046942 8.1197746894586e-17 318.041594005901 36.1339302357107 8.80174373314044 3.83757560907425e-15 17.6350263567946 112.121713895945 0.157284666315044 0.875240826504327 ZNF318 other 1.11849896347292e-12 1 5.35763930782856e-11 8.80174373314044 0.157284666315044 2.19512348086543e-22 269.839076697514 29.4956601086023 9.14843321708932 4.06058567232879e-16 -271.550559548575 104.702529407348 -2.59354345196475 0.0104466552327621 ZNF561 other 3.13529486772009e-18 1 5.7108076895632e-12 9.14843321708932 -2.59354345196475 3.96641454212885e-14 410.841102057795 50.4159263625598 8.149034079098 1.25455058048016e-13 -471.142149306316 247.581881710541 -1.90297507253438 0.0589344631538091 WIPF2 other 5.23051085670532e-10 1 1.72325067734755e-09 8.149034079098 -1.90297507253438 0.504939258234508 -21.1195676196982 78.2599371626626 -0.269864356980014 0.787630639598058 -145.600470153302 135.601290168602 -1.07373956377751 0.284641048635896 HOPX other 1 1 1 -0.269864356980014 -1.07373956377751 0.0506391071419767 1.79362104149346 20.633553390785 0.0869273947886503 0.930840701732871 -160.491547628045 67.7888408385379 -2.36752163988628 0.0191338609894943 LRRC8C other 1 1 1 0.0869273947886503 -2.36752163988628 2.00893223309641e-10 952.199974611001 205.988522877734 4.62258751753943 7.96622140505917e-06 -1061.54930542962 465.800929792258 -2.27897635563556 0.0240425363336711 RSL1D1 essential 2.34783910081978e-06 1 0.081582073409211 4.62258751753943 -2.27897635563556 6.0597746316353e-10 350.742075428917 61.5230641618732 5.70098515421924 5.79794892222397e-08 -507.264479883102 202.125980211967 -2.50964512009362 0.0131055652542832 LRRC8D other 6.9172327420117e-06 1 0.000682244649678094 5.70098515421924 -2.50964512009362 2.71632462453319e-12 162.603135313531 45.2380828014654 3.59438608455494 0.000435590863097385 -214.830229451517 67.7972590611204 -3.16871555615314 0.00184280073418784 PPID other 3.40382638700254e-08 1 1 3.59438608455494 -3.16871555615314 0.384399425660708 12.4176541429399 10.755586366856 1.15453065220188 0.250048202625622 -16.4335776624689 35.6299361718566 -0.461229500474085 0.64527638680254 COL24A1 other 1 1 1 1.15453065220188 -0.461229500474085 2.06740830728671e-12 75.230198019802 24.2257298756621 3.10538416823431 0.00225765139366267 -134.185643564356 36.3065360557628 -3.69590872999456 0.000302821579287897 ETFDH other 2.59935246475158e-08 1 1 3.10538416823431 -3.69590872999456 0.640935099560021 -1.1023102310231 6.06024792624572 -0.181891936507946 0.85590366827287 -7.52860286028602 9.08235215080754 -0.828926552866224 0.408412473609932 RXFP1 other 1 1 1 -0.181891936507946 -0.828926552866224 0.0169245889202076 477.950499168053 221.832926127475 2.15455165971801 0.0327516319135754 -931.028868552413 727.541719225169 -1.27969138256973 0.202578221532187 LPAR3 other 1 1 1 2.15455165971801 -1.27969138256973 0.0234245318715677 20.849583066068 8.8435485216674 2.35760373960575 0.019693016883103 66.2635236262563 36.021018532539 1.83957939907774 0.067820131945641 PTGER4 other 1 1 1 2.35760373960575 1.83957939907774 6.72584395128859e-09 115.73961611888 152.816691723126 0.757375485713153 0.449989777788342 -878.519056464232 217.022565479734 -4.04805396398408 8.17722480903835e-05 TBCA essential 7.24776944190859e-05 1 1 0.757375485713153 -4.04805396398408 0.698475534751888 13.5560944542426 31.8446033781045 0.42569518901791 0.670928174722469 -67.486648125537 114.598596064121 -0.588895941515516 0.556799525628263 MAP6 other 1 1 1 0.42569518901791 -0.588895941515516 0.0467827545216529 265.297686805662 139.897320428625 1.89637432649052 0.0598079376385272 717.483462689595 310.986584144158 2.30712030444698 0.0223980730636049 ECEL1 other 1 1 1 1.89637432649052 2.30712030444698 3.17312859266864e-09 329.103511338697 74.2038827882511 4.43512521141016 1.72248463613864e-05 -113.883915508414 117.920934627249 -0.965765034583587 0.335647043088342 PLRG1 other 3.48790294906137e-05 1 0.170870475904953 4.43512521141016 -0.965765034583587 8.86678370828271e-10 73.5899270252543 15.050996382565 4.88937244782681 2.75358721193276e-06 -24.2202829967673 26.5584472490746 -0.911961560464012 0.363367880335328 ZNF584 other 1.00336524442927e-05 1 0.0292486033651498 4.88937244782681 -0.911961560464012 0.236852951887948 14.4403299677319 8.53105907316731 1.69267729175044 0.0925259646369791 7.84074763193507 35.0371125820499 0.223784069351423 0.823220012038624 DNAI2 other 1 1 1 1.69267729175044 0.223784069351423 0.209444987356885 4.1693301374605 2.39330343198883 1.74208171088268 0.0834777671635209 5.86533076845548 5.38259845505504 1.08968387990137 0.27754363681619 NMUR1 other 1 1 1 1.74208171088268 1.08968387990137 4.73968326527821e-10 1793.85885059205 393.657928750599 4.55689754880702 1.05956661241679e-05 -1513.39305377479 835.805789146529 -1.81069941537515 0.072162243389878 CLSTN1 other 5.44068242021285e-06 1 0.107344693503944 4.55689754880702 -1.81069941537515 1.07667771717031e-05 1139.27098729074 311.238027294314 3.66044919765995 0.000347498268615761 -545.7687132248 453.185531872429 -1.20429421250463 0.230360183774102 CXXC5 other 0.0886967103404899 1 1 3.66044919765995 -1.20429421250463 7.09776948168044e-07 78.8609557702084 23.497969116993 3.35607538581616 0.00101111450628268 -77.6265039823763 46.7778584575752 -1.65947109470133 0.099197224277295 ZNF274 other 0.00655266078548738 1 1 3.35607538581616 -1.65947109470133 2.90093613285947e-06 140.521820512996 39.7116655687769 3.53855267716298 0.000533994657951989 -100.075139356458 84.3149281519054 -1.18692076895515 0.237110584342079 PIK3CD other 0.0252845593340032 1 1 3.53855267716298 -1.18692076895515 9.7657636872515e-06 84.7725208640161 29.4444898043909 2.87906231105334 0.00456032679858587 -101.520066273932 63.2052097105999 -1.60619776026005 0.110292396527579 SLC25A33 other 0.0807726314572572 1 1 2.87906231105334 -1.60619776026005 0.433944947696236 -239.014492753622 215.523292644951 -1.1089961081254 0.269171997152406 -387.66746297181 307.744636608097 -1.25970501791553 0.209693974216338 ENC1 other 1 1 1 -1.1089961081254 -1.25970501791553 0.0452020743183897 119.874202258223 117.324325930644 1.02173356895386 0.30851983468404 -316.86021109475 251.847074745213 -1.25814529080915 0.210255870974548 SPSB1 other 1 1 1 1.02173356895386 -1.25814529080915 0.0428539708195112 52.5456082379159 29.2491549880334 1.79648295000022 0.0744167659858647 -140.848527845781 116.557431377729 -1.20840452797326 0.228780693799528 P2RY6 other 1 1 1 1.79648295000022 -1.20840452797326 1.79060745679966e-11 773.135209445254 102.912600743793 7.51254174763323 4.31082097306102e-12 637.065502183407 415.364232034076 1.53375147172312 0.127129420934918 BPTF other 2.18239236834743e-07 1 5.79115689521017e-08 7.51254174763323 1.53375147172312 0.00138406459061708 82.8251783926284 22.7755433755278 3.63658407735833 0.000377698272568941 63.0634830606216 45.4146282617297 1.38861607976134 0.166981005236271 ZIK1 other 1 1 1 3.63658407735833 1.38861607976134 2.37337789249947e-06 150.986284522632 53.2558979860196 2.83510916597947 0.00523574172259285 -261.214501510574 120.986543366563 -2.15903764370844 0.0324923061554192 PLEKHG5 other 0.0209023390992428 1 1 2.83510916597947 -2.15903764370844 1.53701972352907e-07 441.366314001741 92.11790288615 4.79131960426013 3.8856021882958e-06 -539.0639283063 347.455145286246 -1.55146336331327 0.122856741791664 ATF7IP other 0.00150581822314143 1 0.0408376789989888 4.79131960426013 -1.55146336331327 0.225647428748177 -6.27538785072592 5.70554384956479 -1.09987549236075 0.273663705800946 -33.1638473316239 19.6040238669882 -1.69168572516735 0.0933906890351317 LKAAEAR1 other 1 1 1 -1.09987549236075 -1.69168572516735 0.0797293571501999 45.6485915622867 32.9960111233488 1.38345787894297 0.1691811838104 -114.222223247062 113.372994167222 -1.00749057644705 0.315796046607721 RGS19 other 1 1 1 1.38345787894297 -1.00749057644705 0.00030647089017349 234.194386540981 80.4620272286441 2.9106200105484 0.0043259247562188 -384.001604899553 276.464355329933 -1.38897328894817 0.167501744167798 TCEA2 other 1 1 1 2.9106200105484 -1.38897328894817 0.324069862319244 -10.6603162221355 15.2611145822963 -0.698528024584919 0.485893758249775 -36.461012270859 24.4268656393461 -1.49266028680031 0.137558792164196 ANO5 other 1 1 1 -0.698528024584919 -1.49266028680031 2.25923438164632e-07 261.175209348147 53.2849102053232 4.90148539880725 2.54683332238773e-06 -28.2268109298888 79.3366520137945 -0.355785254524995 0.722525698731438 HDAC3 essential 0.00218083894860319 1 0.0271186812167845 4.90148539880725 -0.355785254524995 0.00143726628054905 46.0271305292847 19.3327020252973 2.38079139010456 0.0185143042683958 -32.9520849236024 28.069908052352 -1.17392920782444 0.24225945047331 GPHN other 1 1 1 2.38079139010456 -1.17392920782444 0.684107331414713 -5.80398825615533 6.66535764327984 -0.870769217013739 0.385235533444011 -6.15700124996369 12.1333022549895 -0.507446457738394 0.612567535360784 VAT1L other 1 1 1 -0.870769217013739 -0.507446457738394 0.0786129964782973 51.830283689498 30.2936928041083 1.71092656232617 0.0890951834465327 -16.037774111689 70.4985099107182 -0.2274909658658 0.820341786287731 TMEM51 other 1 1 1 1.71092656232617 -0.2274909658658 5.96485684895924e-07 201.59926249066 64.5943347614639 3.1210053209021 0.00215752750569144 -310.750090381048 144.437323488011 -2.15145284388243 0.033020160928575 CAMTA1 other 0.00554910632658678 1 1 3.1210053209021 -2.15145284388243 0.101948351828232 12.2083074253488 6.01986920468837 2.02800210606583 0.0443419397681459 27.0829007302436 35.5979494860116 0.760799459555556 0.447979166195788 LRRC34 other 1 1 1 2.02800210606583 0.760799459555556 4.38944799315187e-17 98.1802399873228 13.3261286137905 7.36749905638168 1.44044053728212e-11 -45.1782642557797 20.6701076178907 -2.1856811338842 0.0305257289412805 SPATA5L1 essential 6.06007189934547e-13 1 1.91477760620913e-07 7.36749905638168 -2.1856811338842 0.705416583361239 11.1266265718973 39.2515388299009 0.283469818090835 0.777238480399516 -34.2249589939857 63.8032692660318 -0.536413876400009 0.592529992356684 GATM other 1 1 1 0.283469818090835 -0.536413876400009 0.731507273972142 -14.890387258356 19.5128847749764 -0.763105375246802 0.446666456575031 -20.9970513205107 37.1575714720222 -0.565081368041517 0.572910096153023 SYCE1 other 1 1 1 -0.763105375246802 -0.565081368041517 0.463184901711311 -1.18882722087285 2.66940774992164 -0.445352427296936 0.656698702924963 -12.573260504017 10.1344709156722 -1.24064301024076 0.216649181161052 RASGRP4 other 1 1 1 -0.445352427296936 -1.24064301024076 1.82816405116673e-06 10.0789107470428 2.00932365542024 5.01607131327724 1.46306709838375e-06 -12.407361313176 14.0553949100557 -0.882747257730862 0.378776003436174 SLFNL1 other 0.0162907698599467 1 0.0158230706690202 5.01607131327724 -0.882747257730862 1.22647710061612e-21 213.03972985257 19.8076484216311 10.7554276670177 1.90866606302139e-20 124.094205507193 58.0113509483288 2.13913662548085 0.0340112605670346 BCL2 ts 1.74772986837797e-17 1 2.73626366794747e-16 10.7554276670177 2.13913662548085 1.22425549499401e-11 180.474671212859 28.6688820550351 6.29514157079463 3.17048685930027e-09 -275.04144710623 135.905172660799 -2.02377467848628 0.044756940384934 RHNO1 other 1.50044753466466e-07 1 3.93203780290419e-05 6.29514157079463 -2.02377467848628 3.06543418823701e-12 143.55979329729 20.6166399311294 6.96329730629513 9.71949564638968e-11 -348.109520586666 144.242314703115 -2.41336615613219 0.0170118623230607 CTPS1 essential 3.83516471290332e-08 1 1.26693625750689e-06 6.96329730629513 -2.41336615613219 0.0978360708751467 -31.3140064601196 17.421960012181 -1.79738711592873 0.0743992438415827 -65.0130295356294 33.17591077899 -1.95964565882549 0.0519955216459 KNDC1 other 1 1 1 -1.79738711592873 -1.95964565882549 0.000449332955214087 18.2751178875228 4.53600143688229 4.0289047836113 8.87749692403196e-05 29.7281311820073 17.3189510801705 1.7165087564711 0.0881332437172419 WDR87 other 1 1 0.81672971701094 4.0289047836113 1.7165087564711 0.271060163826634 -11.1518222909589 16.4390930332446 -0.678372113863383 0.49862447686315 -49.7084472552864 30.9451605053107 -1.6063399395442 0.110389897752156 CFAP46 other 1 1 1 -0.678372113863383 -1.6063399395442 0.000753268536063112 237.630344055375 68.0587857247045 3.49154545625574 0.000637910578603973 -81.8791661819448 249.451391434762 -0.328236959156664 0.743209302550966 COL8A2 other 1 1 1 3.49154545625574 -0.328236959156664 3.91240350388557e-07 224.933452706558 44.4075094011731 5.06521207200636 1.22995534700906e-06 54.5596505381633 82.2206354648823 0.663576123313552 0.508022609986773 PWWP2B other 0.00369800379187264 1 0.0133597749792124 5.06521207200636 0.663576123313552 0.318729566082483 -1.47544914690337 5.06623296535441 -0.291231997618995 0.77129007767038 -11.2377999020728 7.86860694058727 -1.4281816320125 0.1553899681386 PCDHB1 other 1 1 1 -0.291231997618995 -1.4281816320125 0.00132406136819812 2.33995447679068 0.955420063183386 2.44913684248385 0.0154875432692847 -5.86483844728946 3.72924182233074 -1.57266241415902 0.1179323749956 ZNF540 other 1 1 1 2.44913684248385 -1.57266241415902 1.19042188266285e-22 186.132172424354 16.7116924567138 11.1378409401962 4.238700217468e-21 -26.0824392643948 68.8187967253077 -0.379001675494322 0.705252727142211 FBXL14 other 1.70230329220787e-18 1 6.08507803219706e-17 11.1378409401962 -0.379001675494322 3.87325245421783e-21 471.241020264781 57.6390740571561 8.17572155648248 9.83159045082329e-14 -257.204782971436 131.916088891576 -1.94976052680608 0.0530093408080383 EXOSC10 essential 5.50737766465233e-17 1 1.3518436869882e-09 8.17572155648248 -1.94976052680608 1.56178190429969e-20 40.8819621472541 4.22323087790641 9.68025744486898 1.79178846356266e-17 -21.2159174384195 16.6225042716852 -1.27633701226107 0.203835624645816 ZNF570 other 2.21242024563094e-16 1 2.539322610561e-13 9.68025744486898 -1.27633701226107 0.0308618715215961 62.3942582461362 27.6081334785767 2.25999552974318 0.0253876807768204 -57.2881234397404 112.443633170229 -0.509483034517495 0.611227443298013 NINJ2 other 1 1 1 2.25999552974318 -0.509483034517495 0.000409483725171965 53.6891546461403 22.3014591526602 2.40742788526177 0.0172406225685054 -90.7432073641215 53.1911708822285 -1.70598251286924 0.0900142626129615 MLLT3 other 1 1 1 2.40742788526177 -1.70598251286924 1.01340804368545e-18 59.4862589000968 5.96624126017953 9.97047492818062 2.24428000620123e-18 -4.82273468397177 27.426793273218 -0.175840268161467 0.860650440091632 FAM90A1 other 1.42039271402952e-14 1 3.1951814448287e-14 9.97047492818062 -0.175840268161467 0.0113100391095573 228.242942808556 102.96463440493 2.21671202085701 0.0281277926142144 -391.910793878099 323.373535322863 -1.21194455039992 0.22741417509374 RRM2 essential 1 1 1 2.21671202085701 -1.21194455039992 1.21683889551944e-12 245.071511443941 36.089020730384 6.79074983150237 2.39810473955505e-10 -171.23800232043 107.51257869823 -1.59272528288125 0.113313022852238 TRAPPC12 other 1.54112646117537e-08 1 3.08732004170317e-06 6.79074983150237 -1.59272528288125 0.290165331064358 1034.60176203869 1185.98166740362 0.872358983679453 0.384769329969308 -3206.11743098203 4048.85560002887 -0.791857687134896 0.430019289525023 RPS21 essential 1 1 1 0.872358983679453 -0.791857687134896 0.715520458303881 -12.9671714318002 16.4548806313189 -0.788044089916977 0.431882231794493 -0.631088258560305 75.3742725588217 -0.00837272768460627 0.993330444325293 C3AR1 other 1 1 1 -0.788044089916977 -0.00837272768460627 1.77382502156693e-12 73.9556401998652 12.4370085509272 5.94641709033415 2.24945364569317e-08 -202.400992906284 50.3525447502879 -4.01967753387731 9.6743380580234e-05 MRM3 other 2.23448737966786e-08 1 0.000269664503045697 5.94641709033415 -4.01967753387731 1.22979810730431e-10 271.863602878677 107.181925945673 2.53646872343455 0.0121739065540175 -813.311214370712 191.754291719766 -4.24142378810119 3.78178539681221e-05 PTEN ts 1.45066984737617e-06 0.545068729242544 1 2.53646872343455 -4.24142378810119 0.00260935777701152 739.551725857486 685.371372793644 1.0790525475889 0.2822736222853 -5463.69727453238 2004.13706899321 -2.72620937912051 0.00715957055753954 RPS7 essential 1 1 1 1.0790525475889 -2.72620937912051 2.90053522687592e-09 84.9113860353785 16.119918417363 5.2674823678958 4.65254107760504e-07 -91.3515227620973 47.137256284427 -1.93798981873023 0.054477927941745 RNASEH1 other 3.19609976649457e-05 1 0.00519502736725378 5.2674823678958 -1.93798981873023 0.0541293863067225 -94.4202738890495 109.432986857022 -0.862813641488313 0.389581611931927 -919.698711765441 377.210306743916 -2.43815901984305 0.0158999333206351 PRNP other 1 1 1 -0.862813641488313 -2.43815901984305 0.598374877983551 8.75432744498175 9.36139486449463 0.935152033612498 0.35117401259804 -0.528497647948935 34.5472858484399 -0.015297805166735 0.987814394346927 ADRA1D other 1 1 1 0.935152033612498 -0.015297805166735 0.00240306769566925 84.5117887548056 32.3599707696101 2.61161511413268 0.00999408440951332 -36.566249317646 53.2251962597869 -0.687010135935802 0.493212778969486 FRMD5 other 1 1 1 2.61161511413268 -0.687010135935802 0.108370827178926 6.75189780923127 5.24720446986325 1.28676095014213 0.200331943271183 -9.27274326463782 12.3997877120494 -0.747814678764791 0.455844394203223 AQP4 other 1 1 1 1.28676095014213 -0.747814678764791 0.0746615616818248 25.091312515933 13.9145180617894 1.80324696870646 0.0733043929265941 -75.4151824350547 86.2264756235411 -0.874617475545588 0.383144034695974 CYP4F11 other 1 1 1 1.80324696870646 -0.874617475545588 7.98545209774632e-05 189.700575619105 61.5233568561784 3.08339117552645 0.00242594604964878 -158.460196483111 100.106290673325 -1.58291946906924 0.115491341624385 TLN2 other 0.593478799904506 1 1 3.08339117552645 -1.58291946906924 0.45847483277882 -0.824460070316434 2.44351261706525 -0.337407740217295 0.736287599739391 -8.95063500035879 7.16958705924344 -1.2484170882365 0.213849643976665 LGALS9C other 1 1 1 -0.337407740217295 -1.2484170882365 9.75306014401325e-07 68.0904828493871 18.8207176620224 3.61784731444031 0.000400753049659811 -141.293205560582 52.793560224075 -2.67633410137302 0.00823857910578732 TVP23B other 0.00890823217140729 1 1 3.61784731444031 -2.67633410137302 0.205628513062294 159.526200417782 131.818881390761 1.21019233917549 0.228059345357098 -561.998483139876 598.621213359769 -0.938821529537273 0.349292508375643 ZNF217 other 1 1 1 1.21019233917549 -0.938821529537273 0.449041815129357 -15.1371065474435 17.5903944970631 -0.86053252244973 0.390842037125132 19.4724214732567 41.0548865233109 0.474302162842426 0.635960664386651 SCG2 other 1 1 1 -0.86053252244973 0.474302162842426 2.02193452830037e-09 119.706718346253 19.4828374679193 6.14421377498858 7.16645217914953e-09 -86.0440270323992 60.0864369078785 -1.43200415035955 0.154265516012985 ATPAF2 other 2.24738022820586e-05 1 8.78033720989401e-05 6.14421377498858 -1.43200415035955 0.24128405931696 68.055817447342 40.6686441576249 1.67342233450343 0.0963283411392416 63.0658455642095 65.2671859036858 0.966271866804174 0.335463475051381 FOXB1 other 1 1 1 1.67342233450343 0.966271866804174 2.75009781586425e-05 151.169787226817 42.4852126741713 3.55817419077484 0.000498511582905628 -365.850708960927 189.981653913143 -1.92571599112506 0.0560066526610035 PPIH essential 0.216872713759055 1 1 3.55817419077484 -1.92571599112506 0.0330265861021418 56.1266149870803 27.5756567842894 2.03536820269163 0.0436103871031521 -101.045716557344 85.0452591564666 -1.18814049788995 0.236694134050264 DRC3 other 1 1 1 2.03536820269163 -1.18814049788995 0.000390451484763818 18.3668686535375 6.39305277614102 2.87294181616692 0.00466511830214609 -10.7597831140976 9.61535498432971 -1.11902089227418 0.264944116163789 ZNF57 other 1 1 1 2.87294181616692 -1.11902089227418 2.03368405249911e-07 37.7136134710282 7.18811599140819 5.2466617839927 5.1199137326602e-07 -13.8668631312728 25.2307378231076 -0.549601966795153 0.583399010618402 C20orf196 other 0.00197389374135563 1 0.00570409588955672 5.2466617839927 -0.549601966795153 7.73487858754673e-09 321.319772344013 58.8013331277468 5.46449808622435 1.85881481179535e-07 -172.717537942665 130.291561241775 -1.325623365754 0.186953361118692 JMJD1C other 8.29643077300262e-05 1 0.00212704178913741 5.46449808622435 -1.325623365754 0.287319638610979 519.455747243389 328.328881713381 1.58212017332321 0.115673730070814 413.22564647538 527.621303414002 0.783186053712353 0.434720631903785 SYNPO other 1 1 1 1.58212017332321 0.783186053712353 0.070190878677978 23.0300955437897 11.0730992316245 2.0798238200572 0.0392662111349924 1.71375110617803 16.6542939057429 0.102901456878162 0.918180478599503 ZNF556 other 1 1 1 2.0798238200572 0.102901456878162 0.671937363717475 -112.610899297991 278.412783704596 -0.404474599907288 0.686508631043752 -766.29656862745 875.033652909745 -0.875733825869768 0.38274184086476 MAL other 1 1 1 -0.404474599907288 -0.875733825869768 4.47677203836685e-06 33.3855724377916 7.46588118945009 4.47175244162313 1.53493486641748e-05 -1.14712543684661 11.2289230859008 -0.102158099051098 0.918769466399326 ZNF554 other 0.0382719241559982 1 0.153002307484495 4.47175244162313 -0.102158099051098 8.16896830375653e-13 59.6446839291846 18.9656481636779 3.1448798066081 0.00199433281876147 -109.500662056789 29.4614516563807 -3.71674360564219 0.000281935321485477 RAB33B other 1.03990966506821e-08 1 1 3.1448798066081 -3.71674360564219 0.00336844157369245 143.457040513424 62.3794603790968 2.2997480202874 0.0228899003262039 -110.870599160876 91.8586590493027 -1.20696949322295 0.229409206473391 THOP1 other 1 1 1 2.2997480202874 -1.20696949322295 0.0375323598441143 -51.3391918289893 32.9341530011055 -1.5588435454 0.121072876865225 -271.397276329743 112.536261542895 -2.41164290166415 0.0170499155511603 EPHX4 other 1 1 1 -1.5588435454 -2.41164290166415 3.53504859604469e-05 1111.35425584751 328.652964662135 3.38154337658268 0.000958381611373499 -1094.42557292529 711.588183511598 -1.53800414099689 0.12653539422166 LAMB2 other 0.274530431922775 1 1 3.38154337658268 -1.53800414099689 6.87409258878865e-14 580.51284776951 84.0290872083477 6.90847499426175 2.16072896419266e-10 -369.752709455908 179.959995226752 -2.0546383599867 0.0419812393744291 USP19 other 9.00781092834864e-10 1 2.7858278535336e-06 6.90847499426175 -2.0546383599867 6.56704636290728e-145 607.502180694249 5.64571707100271 107.604078109843 4.3117821278042e-146 356.907856860649 179.017610837355 1.99370249212472 0.0479619329097031 ORMDL3 other 9.60693212429705e-141 1 6.30770607476476e-142 107.604078109843 1.99370249212472 8.76879031435551e-09 63.0849134377575 27.943166444922 2.25761506170399 0.0256503050881474 -109.698838966749 40.3571267765882 -2.71820240261473 0.00746673446204999 SERF1A other 9.38348251539183e-05 1 1 2.25761506170399 -2.71820240261473 0.00108900591367944 98.4556206927414 30.3637385938962 3.24253946490415 0.00145624776486985 -70.2082072854201 95.3611844637144 -0.736234639704322 0.462722615114358 KLF11 other 1 1 1 3.24253946490415 -0.736234639704322 0.153156158599015 -66.9949418310573 48.0831038335316 -1.3933156657898 0.165519181040177 196.362502107571 180.523473022107 1.08773944363193 0.27839865450387 LRRC15 other 1 1 1 -1.3933156657898 1.08773944363193 2.4265273697037e-10 119.431501831502 55.0272260477382 2.17040745844413 0.0318217116378261 -266.178754578755 79.4473295062865 -3.35038013527808 0.00106086495245709 SMN1 other 2.82350724738723e-06 1 1 2.17040745844413 -3.35038013527808 0.332910194809218 85.1738829817053 80.5110523333868 1.05791541053283 0.29191597315824 -55.7733634817709 121.013851240417 -0.460884129461895 0.645596898025958 MOB3A other 1 1 1 1.05791541053283 -0.460884129461895 9.0094978731802e-12 67.446871458761 11.9606220319056 5.63907723852848 1.05564955400288e-07 -72.2882423202966 26.7648087114791 -2.70086900674515 0.00785978513917476 NME6 other 1.10969985303961e-07 1 0.00122476461255414 5.63907723852848 -2.70086900674515 0.000116234333566834 71.2904301433819 225.970873084218 0.315485040927431 0.752829004416149 -1620.69997178547 479.481287195641 -3.38011099716636 0.000922313376561232 CYCS essential 0.846069714032984 1 1 0.315485040927431 -3.38011099716636 3.29185711213919e-06 47.4517373751402 9.05726083432549 5.23908257067149 5.3011516012772e-07 32.2754803447967 34.9587781514057 0.923243947629185 0.357343330306508 SLFN12 other 0.028520650019574 1 0.00589700104126076 5.23908257067149 0.923243947629185 0.597803236959427 -30.9869957497568 44.1751155730972 -0.70145817045984 0.484075797206187 -71.4552382372662 70.3245066416783 -1.0160787703972 0.311185551169203 CALB2 other 1 1 1 -0.70145817045984 -1.0160787703972 0.82206174142869 8.29349957971421 16.442820231519 0.504384251785258 0.614726589297182 28.1376936316696 63.4202351675348 0.443670597520481 0.657915839302159 CCL11 other 1 1 1 0.504384251785258 0.443670597520481 0.750270609194998 -6.34991913976057 34.5763136228847 -0.183649396781206 0.854530092439578 -33.7527449923396 46.6166438211403 -0.724049228465326 0.470133996680637 FRMD3 other 1 1 1 -0.183649396781206 -0.724049228465326 0.00223603086736663 201.873109691162 63.1162702722268 3.1984321763701 0.00168170281454593 -227.750252928646 345.7238736724 -0.658763453357741 0.511044346025173 SNTB1 other 1 1 1 3.1984321763701 -0.658763453357741 2.19094192652185e-07 60.4699333459315 11.455505677018 5.27867865905264 4.4835597522124e-07 -59.9887455643667 61.6584551558637 -0.972920022286057 0.332159368292835 MTBP essential 0.00211842174875398 1 0.0050112747350478 5.27867865905264 -0.972920022286057 1.23319238313787e-10 56.9963235667496 8.21194446638257 6.94066110652316 1.13922311395009e-10 -40.6667140608341 31.7394490754747 -1.28126716894584 0.202103734379097 TEFM other 1.45455041591112e-06 1 1.48133181506931e-06 6.94066110652316 -1.28126716894584 0.000697332112614421 225.074627639029 59.2554699996951 3.79837722391177 0.000211570646064532 45.2456875841993 318.749103823297 0.141947654256879 0.887313103770158 MRPL13 essential 1 1 1 3.79837722391177 0.141947654256879 5.37962590422387e-09 323.392760087915 71.8893035074818 4.4984823097397 1.34058798866346e-05 17.918284377944 134.682291933643 0.133041130505651 0.894334536928616 MALT1 other 5.82990059240741e-05 1 0.134393945863511 4.4984823097397 0.133041130505651 0.153228735105365 98.468589031411 53.0533416417691 1.85602991223999 0.0653479246389953 107.556660943339 92.7226457640605 1.15998265641626 0.247839516700718 ISG20 other 1 1 1 1.85602991223999 1.15998265641626 2.28674427948191e-05 124.634308375164 34.3842621621745 3.62474866516901 0.00039396779732537 -146.462468415009 100.942123138342 -1.45095490228872 0.148853040984212 MBOAT1 other 0.182070579532349 1 1 3.62474866516901 -1.45095490228872 7.25968722300077e-10 2325.32126797685 361.314995152389 6.43571758486282 1.49737029766419e-09 182.031190320757 1055.35669455477 0.172483096246007 0.863285700497621 ID4 other 8.25426437255188e-06 1 1.87934946059833e-05 6.43571758486282 0.172483096246007 0.840223361145766 1.98733068020014 8.16557756164412 0.243379070885954 0.808031498871452 -7.2182506359 18.1798063932375 -0.39704771765804 0.691874952185268 CXCR6 other 1 1 1 0.243379070885954 -0.39704771765804 0.313125831529422 240.575248342936 158.188490049631 1.52081386115675 0.13037050687176 463.042705161025 762.842116586175 0.606996775732842 0.544752768093396 CEBPB other 1 1 1 1.52081386115675 0.606996775732842 0.734170380055341 -19.6185062708263 37.8423360375475 -0.518427463129143 0.605002506036478 -64.2815466982934 82.3593129698764 -0.780501249710581 0.436452257537786 TPSAB1 other 1 1 1 -0.518427463129143 -0.780501249710581 0.266144318202305 -15.3579505307308 10.1504085540312 -1.51303767222565 0.132306413140776 -46.8458449868424 45.0345293566676 -1.04022059641901 0.299857299485733 CLEC7A other 1 1 1 -1.51303767222565 -1.04022059641901 0.0163607419743601 27.5384677419355 20.3056982310664 1.35619408052679 0.177116888063706 118.623817204301 40.8630574079509 2.90295990385732 0.00426646347615244 C1QTNF4 other 1 1 1 1.35619408052679 2.90295990385732 2.09980817965249e-05 40.7830898852006 12.1834803200848 3.34740885311471 0.00102380734645509 -13.445285695673 18.098749321884 -0.742884795880108 0.458675857567488 SERHL other 0.167690681227048 1 1 3.34740885311471 -0.742884795880108 0.219764084893544 -8.46741675842498 5.46465259867244 -1.5494885732502 0.123290650590863 4.38667204292737 16.1493120074061 0.271632131506014 0.786264028266891 NEGR1 other 1 1 1 -1.5494885732502 0.271632131506014 7.0011356084166e-15 181.754669533106 20.5316040571445 8.85243398553947 2.86024700407255e-15 -76.3492362551711 92.0443745407442 -0.829482916648801 0.408204123388483 ZNF131 essential 9.36681933050057e-11 1 3.99776723759221e-11 8.85243398553947 -0.829482916648801 0.000276100318573504 192.202118105494 57.3375829442494 3.35211406264502 0.00101207793641325 -199.07702727902 178.179428424145 -1.11728401555498 0.265635816192195 MACROD2 other 1 1 1 3.35211406264502 -1.11728401555498 2.71680323269567e-12 296.25179216516 47.5620179227504 6.22874733040824 5.16604687240389e-09 -377.071606150083 135.494005986304 -2.78293938839035 0.00613108310323656 DPAGT1 essential 3.40415445056767e-08 1 6.36198672336539e-05 6.22874733040824 -2.78293938839035 0.000139500506964994 2905.89317378809 1406.72292337497 2.06571822034175 0.0407123211059053 -5152.26616102134 2099.49863440222 -2.45404596916459 0.0153622999507633 BSG other 1 1 1 2.06571822034175 -2.45404596916459 1.84979860247732e-12 117.11220254517 19.3760674622481 6.0441677741548 1.20974608533016e-08 -163.220837916771 54.8702543074557 -2.97466887983044 0.0034367773768891 HINFP essential 2.32963635995993e-08 1 0.000146778492533109 6.0441677741548 -2.97466887983044 0.000931939069005908 298.72782685056 88.4506629055151 3.37733847364906 0.000922848404733664 -192.869113418393 270.351469892748 -0.713401386332046 0.476656517299049 CERS6 other 1 1 1 3.37733847364906 -0.713401386332046 1.82022035871387e-05 102.12091832068 24.7002461587689 4.13440893116064 5.84648752760548e-05 -81.1543217781034 79.4345454546252 -1.02165023181835 0.308559161807278 SPTLC3 other 0.146272908026246 1 0.548342065214118 4.13440893116064 -1.02165023181835 2.50378196261181e-05 153.085006745038 32.3676021983155 4.72957514143587 5.07153199355037e-06 13.8430911543666 126.265354131487 0.109634913310828 0.912842587292648 COPRS other 0.198449758356612 1 0.0528301487768142 4.72957514143587 0.109634913310828 2.19399628935682e-05 73.3954589685374 16.2050624332031 4.52916854045281 1.18467324556111e-05 -10.8326704758102 72.2799683809539 -0.149870990793968 0.881063783326299 TP53RK essential 0.174949264113313 1 0.119509837012204 4.52916854045281 -0.149870990793968 0.000275003297731799 43.3038552266818 10.4539950275524 4.14232598279899 5.60087813376039e-05 28.1143424534095 31.9528743947272 0.879868962838875 0.380275090794348 B3GALT1 other 1 1 0.526426535792139 4.14232598279899 0.879868962838875 0.809307591790041 -0.991561981512203 2.79228630041324 -0.355107562346117 0.722991751356157 -7.75882910642331 12.3748094766155 -0.626985742373252 0.53159101452518 CLEC12A other 1 1 1 -0.355107562346117 -0.626985742373252 3.18546750441795e-05 95.5888141234355 21.7733528671847 4.3901742972944 2.07932839249769e-05 -58.9348093480936 79.6436275125985 -0.739981479858773 0.46042340165421 BPGM other 0.248944285470263 1 0.204772260093172 4.3901742972944 -0.739981479858773 0.01408733341794 29.87336443777 27.740403814947 1.07689003509292 0.283235589763306 -210.801857095365 93.3413327981418 -2.25839776202083 0.0253439957085054 POP7 essential 1 1 1 1.07689003509292 -2.25839776202083 0.0321550115684873 4.01414842498658 12.9586144201081 0.309766792563698 0.757157068819783 -99.6252891973662 40.2743813504156 -2.47366404788582 0.0144592626886217 ALG14 other 1 1 1 0.309766792563698 -2.47366404788582 2.77656246086739e-06 10.5144351317616 53.4630840864106 0.196667201517358 0.844347281487662 -566.822773799624 126.416226280151 -4.48378179351349 1.42492086278426e-05 SUCLG2 other 0.0242588262205984 0.206613525103717 1 0.196667201517358 -4.48378179351349 0.0596267133792999 21.1503893044863 8.89535466347299 2.37768926643657 0.0186567664078215 9.50081423160526 15.7323246801695 0.603904027202096 0.546801809793005 STARD5 other 1 1 1 2.37768926643657 0.603904027202096 0.000832338848421578 78.2599277978339 22.9779513379461 3.4058705515924 0.000843882542834876 18.3150984045654 34.0801975088472 0.537411744747395 0.591769115784113 CSDC2 other 1 1 1 3.4058705515924 0.537411744747395 0.213232000273194 -10.6425068628234 13.5734815703688 -0.784066107700492 0.434335405785256 -71.968040119755 40.7328175154366 -1.76683186947432 0.0794511795793951 RCAN2 other 1 1 1 -0.784066107700492 -1.76683186947432 0.364209559275184 27.3721674554535 22.0128295210574 1.24346429109758 0.215598742733298 43.2277358545434 38.9318913361105 1.11034255904358 0.268593417913687 IL16 other 1 1 1 1.24346429109758 1.11034255904358 0.000103163980447918 20.6686852573449 5.56440459998657 3.71444687134986 0.000289238599493554 -14.4887428007268 15.6384514444241 -0.926481937947428 0.355724546778389 ABCG4 other 0.755263500859208 1 1 3.71444687134986 -0.926481937947428 8.20581078809997e-09 987.279372132828 203.068708151021 4.86179963974849 2.88997513704052e-06 -1695.54019954821 682.713372017919 -2.48353155078338 0.0141016852069839 GNB2 other 8.79416742160674e-05 1 0.0306510763034517 4.86179963974849 -2.48353155078338 0.0264407994240575 25.4691082104736 15.2423602863856 1.67094253986519 0.0967907265929872 -10.9161548815226 30.8180071975016 -0.354213522359342 0.723669769236552 CFAP53 other 1 1 1 1.67094253986519 -0.354213522359342 0.000109195026337179 108.826842206174 34.6050604591163 3.14482450723488 0.00201906589937319 -185.02330706936 98.7843231414668 -1.87300273145965 0.0630951471681121 C2CD2L other 0.797669667393096 1 1 3.14482450723488 -1.87300273145965 0.0193141395475196 20.01282728899 117.599992000184 0.170177114373943 0.865089945944089 -945.508098877866 355.036747290256 -2.66312742580665 0.00854876723323236 GNG12 other 1 1 1 0.170177114373943 -2.66312742580665 0.346073412150423 1.84009562657013 6.70016658035128 0.274634310132877 0.783980190233383 -15.631898484562 14.3821453501792 -1.08689615519477 0.278849695915033 PRSS27 other 1 1 1 0.274634310132877 -1.08689615519477 0.595361831686975 -56.6525600033509 92.2051470407671 -0.61441862869437 0.539845406055045 30.5825107161307 136.95954046131 0.223295950126015 0.823601100421254 MYOZ2 other 1 1 1 -0.61441862869437 0.223295950126015 0.418641746533389 72.8295756877109 61.1236106203313 1.19151298407568 0.235285318739847 31.0473164611239 91.0345749547885 0.341049721784754 0.733531005133826 SYNPO2 other 1 1 1 1.19151298407568 0.341049721784754 2.99742557989469e-05 17.3217582220629 3.93070686256881 4.40677944901307 1.9644144453732e-05 7.83607082047806 5.79471731636174 1.35227835848911 0.178281666695755 DNAJB7 other 0.234938216952146 1 0.193887705758335 4.40677944901307 1.35227835848911 7.06881820383782e-08 60.8775731656718 11.1569383260429 5.45647662348096 1.99524985251699e-07 -37.6257109118183 40.2861236810893 -0.933962056257105 0.351844731897338 CLP1 essential 0.000712527417497929 1 0.00227797675661865 5.45647662348096 -0.933962056257105 1.14936733066604e-07 7.51934320413778 1.52924381952221 4.91703357446759 2.23074230398281e-06 -5.90554495149898 4.28362736179923 -1.37863181194606 0.170007636695593 TTC36 other 0.00113764378389324 1 0.0238488659718803 4.91703357446759 -1.37863181194606 1.731523787489e-05 69.8841632088521 28.3860966457916 2.46191521437002 0.0150345387140168 -227.480290456431 86.1922488136744 -2.63921980905946 0.00925156096296845 RSPH9 other 0.13940498013074 1 1 2.46191521437002 -2.63921980905946 0.210328061412838 -48.3196350999136 96.1649755304655 -0.502466046846814 0.616101977641329 -370.681795880821 212.666160949207 -1.74302199384393 0.0834496064651664 COPS9 other 1 1 1 -0.502466046846814 -1.74302199384393 1.66861470836676e-12 290.438710435337 45.9438527323505 6.3216011101052 3.24288485362505e-09 -218.226731111335 132.664720053918 -1.64494924515457 0.102223764823465 GTPBP2 other 2.10362256283797e-08 1 4.02052864152433e-05 6.3216011101052 -1.64494924515457 0.0866061412473735 31.7371757406824 14.2692608878983 2.22416395565369 0.0275733699897289 20.8340601537563 44.7668186978245 0.465390679073846 0.642300738281202 FGGY other 1 1 1 2.22416395565369 0.465390679073846 0.0361665558926447 44.4482190088747 21.4916504977353 2.06816219226897 0.0403652703583419 -4.9701319799681 35.3894445665998 -0.140441084646433 0.888502456282339 IL17D other 1 1 1 2.06816219226897 -0.140441084646433 0.0631695894017304 -6.42545384189425 6.32875409041359 -1.01527942942626 0.311618435102467 -32.0125978236938 13.5620273867138 -2.3604581314336 0.0195476875776815 PRSS30P other 1 1 1 -1.01527942942626 -2.3604581314336 8.87712425279942e-25 654.930411119713 63.4140832879258 10.3278385046751 3.19414454934152e-19 -38.1112388946621 161.725185059006 -0.235654322366409 0.814022355074619 ZNF24 other 1.27777326494795e-20 1 4.56283548873436e-15 10.3278385046751 -0.235654322366409 4.80863444909752e-07 74.5441318015194 26.1932568837198 2.84592832928125 0.00504823919871553 -116.982169796509 53.04946345526 -2.20515274193428 0.0289655538188284 MANEA other 0.00450857565947384 1 1 2.84592832928125 -2.20515274193428 0.864064979871226 -6.93908629441631 51.7854540819166 -0.133996822417348 0.893593486927475 45.7925313526425 113.178446988836 0.404604697899413 0.686372655057896 C2orf54 other 1 1 1 -0.133996822417348 0.404604697899413 0.00472445287271064 142.984125246333 102.776282858666 1.3912171297629 0.166153266959643 -216.620648127873 154.648146668013 -1.40073226091029 0.163292936398058 AFF1 other 1 1 1 1.3912171297629 -1.40073226091029 0.043057560737348 54.1461958866677 23.4324490970517 2.31073566669906 0.0222100663537072 -48.428002301165 76.7121357497066 -0.631295189840288 0.528808349494283 CARNS1 other 1 1 1 2.31073566669906 -0.631295189840288 8.91828701893639e-12 130.93147256368 21.5387272608022 6.07888623029083 9.46408146056692e-09 2.97345076669631 37.3210118118987 0.0796722977844966 0.936603383694799 BANP essential 1.09864377786277e-07 1 0.000115319832597008 6.07888623029083 0.0796722977844966 0.242526579827396 358.133611390766 250.302624817695 1.43080246022833 0.154566806613052 -527.637839781391 819.429879224138 -0.643908469973019 0.520618119745947 PPP1CA essential 1 1 1 1.43080246022833 -0.643908469973019 0.455613160602337 -7.63794362494577 11.7604614614946 -0.649459517379778 0.517034667413217 -41.6126284017337 33.7874767749207 -1.23159917146051 0.220026187438621 MUCL1 other 1 1 1 -0.649459517379778 -1.23159917146051 0.0011627341149877 87.6305876408752 31.1119481586963 2.81662167839468 0.00551112960040833 -292.586737963912 188.450772278688 -1.55258975288901 0.122642654731986 PDE3A other 1 1 1 2.81662167839468 -1.55258975288901 0.000950880289901511 93.3736570820022 29.3803544001438 3.17809839222175 0.00179620467109031 -8.29761022364219 42.5464432609591 -0.19502476794003 0.845633998654037 RASGRP1 other 1 1 1 3.17809839222175 -0.19502476794003 0.545539209624664 12.9937532535138 12.3926015721871 1.04850891701996 0.296125021303029 -14.4686100989068 54.1169879128625 -0.267358008213682 0.789568263640076 KLHL6 other 1 1 1 1.04850891701996 -0.267358008213682 0.00782601090086841 122.666169922118 51.0078977693853 2.40484660780789 0.0175055352694663 -107.334521972076 115.676223125732 -0.927887504205691 0.355085987284605 CHCHD1 essential 1 1 1 2.40484660780789 -0.927887504205691 5.30650499134245e-08 138.995806536291 53.9787786083495 2.57500836661744 0.010977975888591 -615.655276282977 136.926134752175 -4.49625834686172 1.36408847823682e-05 MRPL52 other 0.000538875581870825 0.197847392883468 1 2.57500836661744 -4.49625834686172 0.110263494488871 -14.5506309583746 8.58346086155695 -1.69519395417099 0.092099743506496 -33.7274373507869 16.605288367863 -2.03112626553726 0.0439964210451744 SMPDL3A other 1 1 1 -1.69519395417099 -2.03112626553726 0.0829353026787263 1.39339558955895 4.48109947216463 0.310949488672222 0.756291824470136 -23.8670398289829 12.2015184053297 -1.95607128851747 0.052405656743526 RND1 other 1 1 1 0.310949488672222 -1.95607128851747 0.00475160310122693 135.348770314972 44.2445048691317 3.05910916429763 0.00263014522017861 -112.055932690925 144.845741460564 -0.7736225556996 0.440371539519277 RAD9A essential 1 1 1 3.05910916429763 -0.7736225556996 0.0322187332824398 389.586014460358 172.28690964928 2.26126300166059 0.0251712898486659 -425.831285553516 552.558019861455 -0.770654429484685 0.442115914196792 EFEMP2 other 1 1 1 2.26126300166059 -0.770654429484685 0.0175572269263839 21.8992342744398 8.30658472408476 2.63637042200309 0.00929897999099323 -0.519182286528537 18.781822019328 -0.0276428072843122 0.977985311752643 AGAP5 other 1 1 1 2.63637042200309 -0.0276428072843122 5.86060016573252e-07 243.91306424159 48.2851633486613 5.05151163060841 1.22600207120702e-06 -29.6781678201928 115.733108400151 -0.25643628025249 0.7979562281316 WASHC2C other 0.00545504663426383 1 0.0133192865015931 5.05151163060841 -0.25643628025249 0.309773638204859 43.9893571120374 75.1485169118331 0.585365605600005 0.559181509166913 -319.868891126133 246.01795599142 -1.30018514232875 0.195531766568859 TMEM134 other 1 1 1 0.585365605600005 -1.30018514232875 0.583671853900988 18.7535103237135 22.7657826854452 0.823758646159051 0.411438956579073 73.2958398339329 115.505727710945 0.634564547459991 0.52671932908654 ZMAT3 other 1 1 1 0.823758646159051 0.634564547459991 0.000124077758164991 36.2057410910776 10.5676633408241 3.42608767173823 0.000786460491794846 -25.8901857071155 24.0556758928032 -1.07626099646866 0.283504704018208 ZFAND4 other 0.899687824454352 1 1 3.42608767173823 -1.07626099646866 0.338030941569358 0.799580185591226 3.45896024590943 0.231162004980199 0.817499819393346 8.6433385636944 6.77474284123214 1.27581795593623 0.203966088737683 THEMIS other 1 1 1 0.231162004980199 1.27581795593623 0.0872915892425748 113.955928302898 51.2130075421773 2.22513642084089 0.0275446607098564 52.7127652187738 197.669494329692 0.266671220045995 0.790083746533501 SLFN11 other 1 1 1 2.22513642084089 0.266671220045995 0.000118007378816068 20.4737076197048 4.97652733778585 4.114055089028 6.34944919584392e-05 5.90781723696993 7.20597222761947 0.819850125750708 0.413585287971584 FAM71D other 0.858385673508081 1 0.593863983287282 4.114055089028 0.819850125750708 0.927876458815828 4.87298777008897 14.0083265062758 0.347863662936885 0.728465047951499 0.636352638643409 34.740176833101 0.0183174841538827 0.985411658965891 CCL19 other 1 1 1 0.347863662936885 0.0183174841538827 0.000472566550245419 353.710484682871 121.252501289831 2.91713969543106 0.0040759613604861 -881.338889687905 396.951180835267 -2.22027023029227 0.0279000706368649 CORO1B other 1 1 1 2.91713969543106 -2.22027023029227 5.66415530108966e-14 60.181515574916 10.0177357617641 6.00749680427965 1.36705907437216e-08 -7.08077860880521 19.412742728769 -0.364749005729713 0.715812502236303 FUT10 other 7.44270006563181e-10 1 0.000165400477408288 6.00749680427965 -0.364749005729713 0.000336258975022415 144.00195655019 37.5284537564295 3.83714067957087 0.00017999623571207 19.0838371940847 82.448535755668 0.231463627815521 0.817256031664711 LRRC20 other 1 1 1 3.83714067957087 0.231463627815521 0.000423842198207249 95.2253534154502 34.7541112682337 2.73997377405214 0.00688522586894276 -244.115374535588 111.46327334742 -2.19009694587656 0.0300513793887595 MUS81 other 1 1 1 2.73997377405214 -2.19009694587656 0.000310737621448019 14.5033613445378 4.30945817484737 3.36547212110987 0.000967578377457834 5.66117647058824 8.16904753364756 0.693003247596537 0.48936501840845 PURG other 1 1 1 3.36547212110987 0.693003247596537 3.07313902270408e-06 6.22330870657487 2.35762801495354 2.63964826813339 0.0091704303837309 -20.5949220317819 6.98870472782182 -2.94688684582626 0.00371969383273816 TMEM217 other 0.0267097502060891 1 1 2.63964826813339 -2.94688684582626 1.51442412539138e-13 33.1600396539293 7.71028370677243 4.3007547990488 3.39721651131439e-05 -33.8659336697909 14.4647871605926 -2.34126733382252 0.020800783468711 ZNF596 other 1.96738838129594e-09 1 0.326880172718671 4.3007547990488 -2.34126733382252 0.00525940432612784 3253.40034223874 1220.26752228641 2.66613695998632 0.00850858163151894 -4719.90889049902 3913.63805403681 -1.20601568804518 0.229697714020816 CFL1 essential 1 1 1 2.66613695998632 -1.20601568804518 5.51351596435878e-13 206.121196182267 25.0322400508784 8.23422896885465 7.44284260191314e-14 63.5429750335762 99.7046663310855 0.637311947091537 0.524874189948617 TMCC1 other 7.0567490827828e-09 1 1.0247305694314e-09 8.23422896885465 0.637311947091537 2.55864854092597e-14 111.501168607064 16.7879636412449 6.64173279081487 5.02663564029284e-10 -27.855606037439 29.2547263856589 -0.952174553616549 0.342500528670401 NAA16 other 3.38585961420734e-10 1 6.40644712355323e-06 6.64173279081487 -0.952174553616549 0.712464233210864 5.92666760187982 17.4705497616903 0.339237613167498 0.734895913354402 -50.169463313568 72.2150363101891 -0.694723230465086 0.488282413784572 EFCAB12 other 1 1 1 0.339237613167498 -0.694723230465086 5.08521083529035e-13 287.494396579868 75.9720032946801 3.78421502806416 0.00022234416714358 -315.696999481071 122.080929038526 -2.58596491661237 0.010662323345091 FAM192A other 6.51466360109046e-09 1 1 3.78421502806416 -2.58596491661237 0.182297603986495 96.481327326238 52.1772878294109 1.84910583397273 0.0663849309919565 24.3435956090552 212.899771777477 0.114342985930953 0.909116806559171 RAB43 other 1 1 1 1.84910583397273 0.114342985930953 0.00188213249381276 30.8710877544211 15.9116608875577 1.94015495758592 0.0543566765967105 -103.962922922923 45.3403157138112 -2.29294660361738 0.0233303947538977 HOXC5 other 1 1 1 1.94015495758592 -2.29294660361738 0.63895449542826 -1.87056211367237 4.8244624239382 -0.387724465298134 0.698748468831565 18.4071586370027 21.3214260574649 0.863317424800397 0.389288321206382 RAB37 other 1 1 1 -0.387724465298134 0.863317424800397 2.26357273337339e-07 210.271672591147 43.3203133241845 4.85388161940552 2.95955906841629e-06 27.3608606750758 64.6289902926859 0.423352748529203 0.67263241927339 DCP2 other 0.002184800402252 1 0.0313683665661442 4.85388161940552 0.423352748529203 0.0109913812264712 212.816516872986 93.2357685163877 2.282563014811 0.0238523014763768 -413.278616245548 299.025455483242 -1.38208506555961 0.168986659518257 SNX32 other 1 1 1 2.282563014811 -1.38208506555961 0.000140182599206488 4502.99476943895 1122.06094984088 4.013146318012 9.30134898816914e-05 -7370.30522665764 4608.31128776847 -1.59935055737666 0.111779132856223 RPL38 essential 1 1 0.854049864093691 4.013146318012 -1.59935055737666 0.586846629474415 0.895877067763854 3.47125868188538 0.258084213786472 0.796707861192482 13.2539675875388 12.9009303169659 1.02736525676048 0.305959277712398 CYP7B1 other 1 1 1 0.258084213786472 1.02736525676048 0.445343999553379 -8.61820199778024 19.1570850117719 -0.449870217336532 0.653449169049714 -77.8598393760019 61.4094230762069 -1.26788097780011 0.20679197985936 OVOL1 other 1 1 1 -0.449870217336532 -1.26788097780011 0.000612281371102517 282.807949470262 101.581773685489 2.78404224704595 0.00610595664918631 -453.094133526502 260.388983621585 -1.74006644683928 0.0840292243928611 RARG og 1 1 1 2.78404224704595 -1.74006644683928 0.00145484360963584 -18.3876216620911 19.2574785534495 -0.954830177328558 0.341274897692533 -97.803024706763 30.3521729258551 -3.22227423208474 0.00157509941726096 CES4A other 1 1 1 -0.954830177328558 -3.22227423208474 0.146246165653495 -33.2120289493386 51.0977730207006 -0.649970184334332 0.516754262321831 -143.92367357125 80.5364232158307 -1.7870631426671 0.076045622015426 CES3 other 1 1 1 -0.649970184334332 -1.7870631426671 0.0360001205683692 164.164964763411 94.7683939692108 1.73227547590124 0.0852800778887985 -503.832187544945 310.24865872268 -1.62396250033526 0.106483391402769 SSH3 other 1 1 1 1.73227547590124 -1.62396250033526 4.52016485761416e-11 165.817499963377 57.2727072847369 2.89522720026135 0.00437956124330769 -263.289517503382 89.783373568018 -2.93249748856807 0.00391303111446063 CES2 other 5.42464984562276e-07 1 1 2.89522720026135 -2.93249748856807 2.77244405904297e-18 85.5202965003003 15.6974158086143 5.44804938233014 2.1484410619925e-07 -62.3996259564723 24.6080029112387 -2.5357452281499 0.0122878480020071 PDP2 other 3.87587679454207e-14 1 0.00244900796656525 5.44804938233014 -2.5357452281499 5.37388896356639e-11 484.442793922184 73.4759786312101 6.59321322351751 6.48927448039457e-10 -318.50480304495 248.394143842035 -1.28225568493072 0.201679816148282 SP3 other 6.43308247828533e-07 1 8.23748502541287e-06 6.59321322351751 -1.28225568493072 2.19391287757504e-09 167.060213018915 35.4214319523319 4.71635966732612 5.34183893129483e-06 -61.5479476884037 51.7871648628611 -1.18847880264136 0.236474352348933 DMXL1 other 2.43173303350417e-05 1 0.0555444412076036 4.71635966732612 -1.18847880264136 2.48383480054902e-11 78.6891029900333 11.6902257148494 6.73118765278237 3.08155620281191e-10 -57.0605980066446 36.8275430749858 -1.54940007511394 0.12332496653537 METAP1D other 3.01065616174546e-07 1 3.95086320762515e-06 6.73118765278237 -1.54940007511394 5.55061130285419e-13 142.328650458081 20.9211985397758 6.80308301589332 2.03323358182715e-10 -57.877007868056 45.8368323542821 -1.26267468529922 0.208578317858925 ZNF621 other 7.10367234539279e-09 1 2.62510787749704e-06 6.80308301589332 -1.26267468529922 0.0477649372232292 246.327364620938 106.002358399343 2.32379136031057 0.0217380796836221 316.708653945332 164.284404568241 1.92780717547524 0.0561293234448348 EGFL7 other 1 1 1 2.32379136031057 1.92780717547524 6.28701598144276e-07 305.840836283932 64.8830017950667 4.71372821574951 5.37705735631621e-06 -339.459580312481 225.841087541879 -1.50309044296262 0.134850432000178 NADSYN1 other 0.00583372212918074 1 0.0558998882762633 4.71372821574951 -1.50309044296262 1.05993760822158e-07 636.627188668109 109.473157145865 5.8153725101748 3.34879638234585e-08 149.307626729622 374.080963822914 0.399131848901838 0.69034543032156 DHCR7 other 0.00105273003248567 1 0.000398406305607686 5.8153725101748 0.399131848901838 0.00346429721595385 29.4721452412526 12.5404069023198 2.35017455739819 0.0201029816617516 -17.5777701899688 21.7402190389968 -0.808536940609403 0.420097085773948 NBEA other 1 1 1 2.35017455739819 -0.808536940609403 0.0683958597393569 72.5576244723298 65.1349318165367 1.11395870769774 0.26706690169329 -369.860044526687 215.40670042853 -1.71703128914229 0.0880237887692199 RNASEH2C essential 1 1 1 1.11395870769774 -1.71703128914229 0.717969667855294 -3.47565099570746 30.4825949917019 -0.114020837026953 0.909368833679597 -76.2958429640088 93.9226156412495 -0.812326641917974 0.41785007721619 MYEOV other 1 1 1 -0.114020837026953 -0.812326641917974 0.00377688214630828 133.744874715262 46.6972646523393 2.86408370406684 0.00477793777668385 -202.89034738041 153.047865716026 -1.3256659701277 0.186952424535506 ANKRD13D other 1 1 1 2.86408370406684 -1.3256659701277 0.168693419606968 37.1291156857059 19.9992971557028 1.8565210265461 0.0652775191652729 48.0825050739346 61.0540078602399 0.787540519600307 0.432168148994579 MRGPRF other 1 1 1 1.8565210265461 0.787540519600307 0.0067170670745168 -31.2260147410663 82.249878125956 -0.379648158180215 0.704729629784375 -541.157080607017 178.424127211193 -3.03298152029895 0.0028425313717412 MYD88 other 1 1 1 -0.379648158180215 -3.03298152029895 2.10171181950334e-11 339.853231916657 55.9127957415393 6.07827291426549 9.16878421698427e-09 -179.429817292135 124.056982438459 -1.4463500059833 0.150111277911536 OXSR1 other 2.55463071660631e-07 1 0.000111767479605038 6.07827291426549 -1.4463500059833 1.33679062970802e-12 136.056678700361 17.0067855843057 8.00014076886568 2.94617555481927e-13 -34.3158213627528 110.733771884273 -0.309894811481868 0.757065405665552 LCLAT1 other 1.69130750470659e-08 1 4.02918968877083e-09 8.00014076886568 -0.309894811481868 0.00943099559073804 -110.125769652467 36.3004446088993 -3.03373060134556 0.00284165728278499 -168.903509922135 102.403720294635 -1.64938841514906 0.101133225850523 MIR4435-2HG other 1 1 1 -3.03373060134556 -1.64938841514906 2.32375328906346e-05 186.212947435378 49.7549328760768 3.74260272643063 0.000258280291290922 -324.597517781761 164.543749751154 -1.97271253555764 0.0503544095919709 KAT5 essential 0.184831336612108 1 1 3.74260272643063 -1.97271253555764 0.494440329901493 -29.3442697461449 24.7432492613835 -1.18595053689824 0.237480317168208 -34.415151617175 69.3318874485479 -0.496382730712688 0.620336795278181 SH3RF3 other 1 1 1 -1.18595053689824 -0.496382730712688 0.126557389748282 62.9940686860797 37.7452906924948 1.66892524949093 0.0971639333642428 -15.9287132843237 89.975676160635 -0.177033549110383 0.859714658004033 GXYLT2 other 1 1 1 1.66892524949093 -0.177033549110383 1.38512156056762e-05 165.734846374882 37.4170059737124 4.42939893403873 1.75717743951723e-05 61.2582948959191 65.1661351329421 0.94003265301754 0.348635723570062 HPSE2 other 0.112790448677021 1 0.174153856030553 4.42939893403873 0.94003265301754 1.73960351193278e-10 303.392159763313 43.1668000283295 7.02836808760907 6.01528221122558e-11 -170.051975287155 173.546635363712 -0.979863279577659 0.328661112896116 DCAKD other 2.03742363317568e-06 1 7.88783956358011e-07 7.02836808760907 -0.979863279577659 7.43056862947115e-09 101.798152193177 30.5205465846891 3.33539741533479 0.00107046168346085 -150.486002195824 58.2557856645081 -2.5831941064612 0.0107317750486297 TADA2B other 7.97820153746318e-05 1 1 3.33539741533479 -2.5831941064612 0.458826135915852 -7.05016560749983 13.6878572992149 -0.515067146989049 0.607254325829647 -32.0351492999371 26.1265596543888 -1.22615260959381 0.222037437135232 CCDC96 other 1 1 1 -0.515067146989049 -1.22615260959381 0.00295025057537867 466.265375854213 146.409871314662 3.18465805391034 0.00176066048194081 -404.89145785877 479.850768375669 -0.843786203009236 0.400123624454327 GRK2 other 1 1 1 3.18465805391034 -0.843786203009236 1.18441001554545e-05 423.497402969751 135.67290527769 3.12145893907817 0.00215937961187803 -1226.22923209249 432.782024926815 -2.83336451484983 0.00524030143056641 RELA other 0.0971097771745713 1 1 3.12145893907817 -2.83336451484983 1.2862293760582e-06 60.6208511107529 15.2689459896349 3.97020535352633 0.000109887881395405 -21.541410431493 28.9612372211813 -0.743801456649727 0.458129934466764 EVC2 other 0.0116170535821225 1 0.999650057053997 3.97020535352633 -0.743801456649727 7.7596397175886e-17 430.076794657763 43.537918096096 9.87821222201084 1.34976953330178e-17 42.9156928213678 188.079464737185 0.228178514232463 0.81985790280307 FAM222B other 1.06904556389218e-12 1 1.91383822126859e-13 9.87821222201084 0.228178514232463 0.00118750729524123 156.115299930311 42.183543813084 3.70085786585546 0.000299245428714847 145.509502983212 100.019623733397 1.45480954188618 0.1477705293818 BNC2 other 1 1 1 3.70085786585546 1.45480954188618 0.783887635422629 28.2706538384421 52.0027915012126 0.543637236046895 0.587487579679969 -1.40772134353478 79.6393735575076 -0.0176761980996531 0.985920349883768 HPSE other 1 1 1 0.543637236046895 -0.0176761980996531 0.0223715519586323 32.7671450614146 18.8619081536493 1.73721262952258 0.0843753012623391 -19.6190296306412 28.8859598896888 -0.679189118366271 0.498050955961323 COQ2 essential 1 1 1 1.73721262952258 -0.679189118366271 0.370918354788887 83.0723715154737 204.128669054916 0.406960824758648 0.684636863504376 -727.503245429745 612.498874815441 -1.18776258266426 0.236868942770988 TRMT112 essential 1 1 1 0.406960824758648 -1.18776258266426 0.712127762597109 -3.38523326748149 4.17966603539734 -0.809929128024141 0.41923879692794 -1.71686603130494 12.8136422579904 -0.13398735478465 0.893588657488379 LRRN3 other 1 1 1 -0.809929128024141 -0.13398735478465 0.000383474103195332 841.702733485192 247.352985252334 3.40284040892629 0.000853944258574275 -1319.25264806378 810.686594883047 -1.62732757195042 0.10575244305821 KDM2A essential 1 1 1 3.40284040892629 -1.62732757195042 0.015281972707563 63.0673809866246 21.3814875388247 2.9496255053399 0.00391557383683725 71.619732489573 82.2055965920632 0.871226965786508 0.38559917054554 ADCK5 other 1 1 1 2.9496255053399 0.871226965786508 5.84010952429539e-05 47.5756870258768 116.712741268324 0.407630619492519 0.684133913430013 -668.217258357375 189.507490883843 -3.52607306044147 0.000561799099315158 MRPL57 other 0.441156349089226 1 1 0.407630619492519 -3.52607306044147 1.15727866816162e-13 135.307221895856 24.6299515291086 5.49360487924407 1.54454965012593e-07 -95.6267659890021 43.2211305007301 -2.21250034141024 0.0283663216044707 NOC3L essential 1.50677682594642e-09 1 0.00177680422090817 5.49360487924407 -2.21250034141024 0.131127691156108 13.4217334044089 62.350055565266 0.215264177116241 0.829863842048193 -351.713994543915 187.084641541124 -1.87997257095315 0.0621179350741937 ESRRA other 1 1 1 0.215264177116241 -1.87997257095315 0.958042253762044 10.9202733485194 80.0597793983312 0.136401491867551 0.891685580101762 -60.9415148063781 262.391779429347 -0.232253902690528 0.816655293394156 RHOD other 1 1 1 0.136401491867551 -0.232253902690528 0.554099359080006 1.90803388396592 29.8997211204131 0.0638144374752469 0.949200205350236 -87.7724437888432 89.0267884745349 -0.985910480348839 0.325713536574595 RAPH1 other 1 1 1 0.0638144374752469 -0.985910480348839 0.261414372981855 67.1600748377901 46.6518943179781 1.43960016671625 0.152023429303775 216.804420222179 211.388486983736 1.02562075785546 0.306689174277326 ADCY5 other 1 1 1 1.43960016671625 1.02562075785546 0.179366614781921 235.117274809105 189.203019319108 1.24267189633247 0.2159150395085 -1045.8129772371 866.004355521862 -1.20763015863458 0.229077667423249 PARP14 other 1 1 1 1.24267189633247 -1.20763015863458 0.824810113541622 0.300457201535423 2.36547313202115 0.127017803528676 0.899092003475814 -6.37679833186056 10.883065263602 -0.585937709405044 0.558775129901735 PARP15 other 1 1 1 0.127017803528676 -0.585937709405044 0.582349777213495 -2.62917614133286 7.96267387694657 -0.33018759551924 0.741704071870071 9.44872019124251 12.7309878653314 0.742182797689483 0.459099784916101 ABLIM3 other 1 1 1 -0.33018759551924 0.742182797689483 5.7726596429472e-13 111.076752939351 16.3962056742376 6.77454010679307 2.52752419737727e-10 17.7778898762175 34.2591138950432 0.518924392810689 0.604563236118908 MFSD4B other 7.38207715140088e-09 1 3.25115437508638e-06 6.77454010679307 0.518924392810689 9.0934540873293e-05 278.493269050153 101.265598707247 2.75012711725785 0.00668546307345372 -847.260346878717 338.794728191812 -2.50080735140316 0.013458627037613 VANGL1 other 0.670278500777043 1 1 2.75012711725785 -2.50080735140316 0.622831552071501 -43.3906960024961 44.6992549146101 -0.970725263438648 0.333187789966992 -46.3438436809053 65.0383929422505 -0.712561328537982 0.477181669466412 GLRX other 1 1 1 -0.970725263438648 -0.712561328537982 0.648020210781301 -18.6810933940775 32.3385092397589 -0.577673301375 0.564345107449814 -86.8839407744875 105.987788715911 -0.819754254967721 0.413648268711873 SYT12 other 1 1 1 -0.577673301375 -0.819754254967721 0.0137773988945097 7.93537874257092 3.46997229337631 2.28687092335534 0.023539462511363 -3.14713770418271 5.39904787622755 -0.582906056091819 0.560792847594592 ZNF483 other 1 1 1 2.28687092335534 -0.582906056091819 0.00199142207077676 10.5740809899389 3.52933008850021 2.99605894738862 0.00319155266145171 -18.2348401661047 16.0842209065315 -1.13370988076269 0.258689541034894 SLC2A14 other 1 1 1 2.99605894738862 -1.13370988076269 0.00448688961157781 152.924414411589 73.8740643463415 2.0700690528497 0.0402198858276268 -434.125834875043 221.663039785974 -1.9584944575975 0.052091082158533 GPR137 other 1 1 1 2.0700690528497 -1.9584944575975 0.240854837435575 307.892116285616 415.993803871816 0.740136303521699 0.460351515923152 -670.962990248826 768.594610427188 -0.872973842317085 0.384045346053525 SNCG other 1 1 1 0.740136303521699 -0.872973842317085 0.119670030365394 75.4590803988765 83.3715953725232 0.905093396158587 0.366838940929871 -164.717886528814 154.038253141345 -1.06933104712418 0.286604661361788 MMRN2 other 1 1 1 0.905093396158587 -1.06933104712418 5.09023083530457e-19 508.668198737491 74.6228761805887 6.81651826856022 2.09120885382692e-10 -107.43417097068 144.175164073254 -0.745164201208008 0.457330736257332 TNKS other 7.15075627743587e-15 1 2.69807766320749e-06 6.81651826856022 -0.745164201208008 0.0305666728821802 30.1930357287697 22.4083443451751 1.34740145294451 0.179830047652679 -65.8293606537431 42.9156130803611 -1.53392567246972 0.127099789924834 ZBTB21 other 1 1 1 1.34740145294451 -1.53392567246972 0.0072476527369236 57.6976463110954 33.2888557124727 1.73324210388756 0.0850940296916548 -40.6031080363004 64.2205287378054 -0.632244997578136 0.528182941962723 PPP1R3B other 1 1 1 1.73324210388756 -0.632244997578136 3.39425976596496e-09 52.3738965913722 11.2031409516465 4.674929719926 6.80578348737605e-06 -0.177050317258538 22.0113049821222 -0.00804360838225357 0.993593567657563 FAM86B3P other 3.72553951912314e-05 1 0.070092764136486 4.674929719926 -0.00804360838225357 2.80294013840649e-05 87.259190293128 20.7629481084369 4.20263971365756 4.41356172996039e-05 33.2793128303694 32.8728464766661 1.01236480552397 0.312921304498543 STOX2 other 0.220815624103663 1 0.419817991753832 4.20263971365756 1.01236480552397 2.82387550382854e-05 417.936871724811 120.991024497974 3.45427996381507 0.00071996368253289 -840.177048712357 385.009600127762 -2.18222363399134 0.0306702546121804 MAP3K11 other 0.222323718416421 1 1 3.45427996381507 -2.18222363399134 2.13482667401216e-08 91.1229567684366 20.7109203711575 4.39975409761782 2.03718250099932e-05 -113.660024961376 49.6872801722703 -2.28750747811726 0.0235549206397182 SFT2D3 other 0.00022300399436731 1 0.200845822773523 4.39975409761782 -2.28750747811726 0.786025701897283 -49.1548082998431 482.677152328898 -0.101837860074116 0.919019592192993 -621.483325993838 1032.83229051313 -0.601727242362916 0.548252156808371 C1QB other 1 1 1 -0.101837860074116 -0.601727242362916 0.928792555733042 -24.3622608208294 271.375044162971 -0.0897734015888317 0.928585469097855 -202.532687457466 580.688162053205 -0.348780465476251 0.727736781137066 C1QA other 1 1 1 -0.0897734015888317 -0.348780465476251 0.21747975929485 -15.4085414987912 12.2133784154641 -1.26161173220356 0.208959732044179 -32.0633939363416 18.380927407399 -1.74438390542987 0.0830491747480771 NDNF other 1 1 1 -1.26161173220356 -1.74438390542987 0.295955433348174 -21.4145447603002 15.1424378424137 -1.41420720911387 0.159306585516883 -71.5530642250228 67.1827698280051 -1.06505082193256 0.288509216392116 OLR1 other 1 1 1 -1.41420720911387 -1.06505082193256 1.28015427284502e-06 1882.74085525933 405.744231078751 4.64021595637647 8.48857863082451e-06 -621.516702642781 877.495702882594 -0.708284611082521 0.480056378277887 DAG1 other 0.0115649137008819 1 0.0867447850283957 4.64021595637647 -0.708284611082521 0.63687656423231 6.44930900308598 7.47597161395093 0.862671681504369 0.389650794399976 -2.64021199516971 23.7759835915891 -0.11104533215205 0.911724059662017 DAB1 other 1 1 1 0.862671681504369 -0.11104533215205 0.0126760932767935 64.6006990679096 30.1407514922876 2.14330087570774 0.0336194620594367 -118.377511144561 95.2353165704095 -1.24300013280306 0.215709189508228 ARV1 other 1 1 1 2.14330087570774 -1.24300013280306 0.017630469686263 82.7223633608556 44.4640764239379 1.8604313867255 0.0647439811914549 -188.311528248008 146.939212030838 -1.28156076002699 0.201935561162985 NAA20 essential 1 1 1 1.8604313867255 -1.28156076002699 0.198886041934735 0.123825713182776 21.7159923028455 0.00570205180845231 0.995457730772311 -222.020125264966 125.802107254501 -1.76483629813778 0.0795481439893376 SAA1 other 1 1 1 0.00570205180845231 -1.76483629813778 0.000155931244911179 71.4904381204869 72.2989968980088 0.988816459256515 0.324304013709569 -439.096405837925 159.625447184785 -2.75079201707495 0.00665802938218547 MINOS1 other 1 1 1 0.988816459256515 -2.75079201707495 0.0114121630515857 255.41966235657 91.0917941561642 2.80398102510407 0.00573464169030198 -100.557700974105 289.458372661192 -0.347399524324028 0.728791480312271 EHBP1L1 other 1 1 1 2.80398102510407 -0.347399524324028 2.86688262167614e-05 26.1729424720826 7.71153046224042 3.39400104820161 0.000877263947912991 -56.5697199114679 26.9311558920447 -2.10053070645134 0.0373222004196007 THAP2 other 0.225451649368612 1 1 3.39400104820161 -2.10053070645134 1.06344944303527e-12 425.795481374116 68.1922963434394 6.24404081114479 4.16689342681746e-09 -482.477299782337 191.506513820577 -2.51937801047525 0.0128037250630495 RNF26 other 1.34919830837885e-08 1 5.14903020751833e-05 6.24404081114479 -2.51937801047525 0.286143532085432 250.679572606692 211.500296363116 1.18524454536135 0.237859619566575 -436.935749898089 634.617832690079 -0.6885021620744 0.492236695139366 PPP1R14B other 1 1 1 1.18524454536135 -0.6885021620744 0.000423519199342461 441.845210940479 120.487519188232 3.66714506130885 0.000342834777529648 -243.171497902728 382.867870298168 -0.635131638790563 0.526336699536334 SSSCA1 other 1 1 1 3.66714506130885 -0.635131638790563 0.0980431480913652 -58.3148587869058 51.255310491357 -1.1377330120113 0.256998993352105 -247.848611972983 114.601789147408 -2.16269408895688 0.0321079142377805 AGR3 other 1 1 1 -1.1377330120113 -2.16269408895688 1.49944812093697e-16 1791.41604180445 198.696332118708 9.01584857003898 2.68261520776088e-15 -13.8127462578105 453.955526748142 -0.0304275318702616 0.975774231687308 SMARCC1 other 2.05739276673761e-12 1 3.74975953740816e-11 9.01584857003898 -0.0304275318702616 7.68939651159113e-09 53.6062462889236 10.5258349239003 5.09282604909599 1.02429530646508e-06 -11.1242200656072 20.6761553525506 -0.538021690973361 0.591343853022567 ZNF417 other 8.24995351728613e-05 1 0.0111894019278245 5.09282604909599 -0.538021690973361 0.00378209645577213 108.87009427498 63.0369758405413 1.72708307819809 0.0861841704019242 -280.201084516693 168.989266490004 -1.65809989200271 0.0993596180839219 PTPRM other 1 1 1 1.72708307819809 -1.65809989200271 0.144676813710266 159.069588598664 129.51798720605 1.22816600249971 0.221374485743064 -447.584522279012 388.625575228362 -1.15171144363313 0.251335115781528 FKBP2 other 1 1 1 1.22816600249971 -1.15171144363313 0.0784177564109347 133.880235663674 123.650817171628 1.08272827245329 0.280713995633727 -626.31052452538 384.210149483139 -1.63012488183336 0.105230642795661 VEGFB other 1 1 1 1.08272827245329 -1.63012488183336 0.00564524668114487 228.476859111187 71.6377889050926 3.18933432484745 0.00173637954395706 91.5177367957835 125.698618737102 0.728072732343958 0.467704089685164 PEAK1 other 1 1 1 3.18933432484745 0.728072732343958 0.000532890936015079 19.6779742981239 19.5106722138584 1.0085749010814 0.314760613010333 -66.4731354199317 35.7271365914528 -1.86057830998509 0.0647106017617013 TNFRSF10D other 1 1 1 1.0085749010814 -1.86057830998509 0.000177926004238129 98.5259301014655 36.1426078248467 2.72603268084415 0.00730145249698721 -145.480423243142 77.1320692405027 -1.88612109950693 0.06152692069169 MST1 other 1 1 1 2.72603268084415 -1.88612109950693 4.49578056760412e-08 130.517538520678 41.8806438513037 3.11641671470185 0.00223700188873065 -326.171028606208 89.722346640943 -3.63533769253162 0.000393689749192279 GMPPB essential 0.000458884322535353 1 1 3.11641671470185 -3.63533769253162 1.58861417826327e-24 294.984676907995 26.3228963675463 11.2063913024284 1.0855667941022e-21 -6.33012140992669 65.9207471085831 -0.0960262388941051 0.923624579488858 MOB1B other 2.28490377259606e-20 1 1.56082793656014e-17 11.2063913024284 -0.0960262388941051 2.92421906828241e-09 105.845606003357 17.5586663424749 6.02811192711792 1.24832515431897e-08 -105.090972997197 73.1271807710667 -1.43709865318337 0.152786566106994 ZNF622 other 3.22073488180625e-05 1 0.000151309491955003 6.02811192711792 -1.43709865318337 0.0885996925226663 121.211579539525 55.9343214675776 2.16703405635814 0.0318000243045495 130.101515620924 95.8791511409542 1.35693228478482 0.176827702277658 CSPG4 other 1 1 1 2.16703405635814 1.35693228478482 8.86970994414719e-07 242.98965786172 54.3533651414646 4.47055407203022 1.52966019715269e-05 -98.2412430911132 91.8631872117917 -1.06942994329836 0.286593887376146 SNX33 other 0.00812731522182207 1 0.152507121656123 4.47055407203022 -1.06942994329836 0.344847098240396 3.8218186134853 4.92373226523219 0.776203580457084 0.438842887097869 -18.1448452600413 17.6857994965148 -1.0259556127851 0.306553227552078 C2orf70 other 1 1 1 0.776203580457084 -1.0259556127851 0.0470796386556586 34.0459575763446 18.3317373924657 1.85721390435897 0.0651906320444683 -65.1899157338353 64.3581184556124 -1.01292451206131 0.312685023706342 NABP1 other 1 1 1 1.85721390435897 -1.01292451206131 8.70478380874865e-08 8.91517549328229 1.6324498565404 5.461224709331 1.8876882062179e-07 -6.16450966958843 5.73881594608318 -1.0741779711189 0.284445185532232 ADGRF3 other 0.00087065247655104 1 0.00215894900145141 5.461224709331 -1.0741779711189 1.18781705115329e-11 124.018004980817 32.3051132973332 3.83895898582267 0.000181270923221966 -218.8649682529 66.2371433748572 -3.30426339515086 0.00118933386781492 CCDC106 other 1.45685761323952e-07 1 1 3.83895898582267 -3.30426339515086 2.46450165102713e-06 21.5109028120376 12.5502303955175 1.71398469463321 0.0885566452122935 -81.0115631285339 25.4753516361738 -3.17999783812606 0.00178305664281578 CEP83 other 0.0216432534993202 1 1 1.71398469463321 -3.17999783812606 1.36603559401745e-07 220.062555500741 101.567898660642 2.1666546064521 0.0318088938355162 -687.447652840499 206.16975559678 -3.33437681414817 0.00107259544820831 NUDT4 essential 0.00134486204231018 1 1 2.1666546064521 -3.33437681414817 0.00225833345761005 133.847380410022 41.8233518561154 3.20030256949507 0.00167360881558175 -137.07089977221 137.073869022609 -0.999978338319182 0.318920755479347 PC other 1 1 1 3.20030256949507 -0.999978338319182 4.34005020617137e-13 185.753837481571 25.403281271819 7.31219858938603 1.26222090557876e-11 21.0604891162949 36.7881852172623 0.572479696726453 0.567815923710783 SCAI other 5.57132244966219e-09 1 1.68014224741589e-07 7.31219858938603 0.572479696726453 1.23645090511739e-07 29.3343872406374 12.5711290500753 2.33347276316933 0.020933547567192 -86.6841318833661 27.2642944298088 -3.17940125340607 0.00178865642814948 NMNAT1 other 0.00122062433353189 1 1 2.33347276316933 -3.17940125340607 0.0028588428779614 185.848519362186 67.491052466478 2.75367641443279 0.00661688299462335 -364.218878132118 221.198428041231 -1.6465708249257 0.101725965512879 LRFN4 other 1 1 1 2.75367641443279 -1.6465708249257 0.532175260425607 -11.8829050717445 13.3681594616759 -0.888896119604999 0.37544526133499 -46.5143182737197 57.0241220135535 -0.815695474674108 0.415934151887071 APOBEC4 other 1 1 1 -0.888896119604999 -0.815695474674108 1.55979781528638e-05 843.126282471434 221.286838872274 3.81010586426282 0.000207301525399559 -295.304739915616 397.706083627981 -0.742520047020069 0.459016330800977 SLC19A1 other 0.126187643256668 1 1 3.81010586426282 -0.742520047020069 0.200541890797424 15.5466627440885 17.7526033953576 0.875739878701621 0.382553261687933 -31.6641415070054 39.6391364635321 -0.798810073376255 0.42564694549892 HSPB7 other 1 1 1 0.875739878701621 -0.798810073376255 0.00267073749612155 131.029612756264 37.9493767530084 3.45274742215304 0.000720128575248688 -5.38493735763108 124.377116315963 -0.0432952420600538 0.96552338269708 RCE1 other 1 1 1 3.45274742215304 -0.0432952420600538 0.0245856356126393 76.3519993627523 294.550952889101 0.259214912102148 0.795811168384311 -2515.38668950136 985.389239284402 -2.55268333489013 0.0116496996390738 UQCRH essential 1 1 1 0.259214912102148 -2.55268333489013 0.000216193271409521 7.63861211244938 2.31766756389193 3.2958187064681 0.00123200495304962 -1.92279082243492 5.23415130274466 -0.367354841543586 0.713886298299419 TAS1R1 other 1 1 1 3.2958187064681 -0.367354841543586 0.00053872349760252 19.6209703438819 5.25867402015657 3.73116307812093 0.000268105027595579 -2.02552227569705 16.3182314185035 -0.124126335982727 0.901378170511994 SPDYE2B other 1 1 1 3.73116307812093 -0.124126335982727 0.000738729300664961 301.57501916688 95.7719712657163 3.14888599640671 0.00196222039045513 -126.514796831077 223.303012549681 -0.566561083912511 0.571821454356711 PSMD1 essential 1 1 1 3.14888599640671 -0.566561083912511 0.648644541905457 -10.4421198229085 12.4290393015808 -0.840138933471749 0.402158772918835 -27.4621744766095 50.9658992706194 -0.538834296453604 0.590794706225673 MUC13 other 1 1 1 -0.840138933471749 -0.538834296453604 0.0735182574748879 9.40205554998496 7.02802748061591 1.3377943634849 0.182935690088484 -16.9122363715365 15.4917130125258 -1.09169569290769 0.276671875717129 SUSD5 other 1 1 1 1.3377943634849 -1.09169569290769 0.223350223403562 212.901415721636 130.924702023397 1.62613633967705 0.106005836114042 -180.619152362622 536.863309661567 -0.336434152068396 0.737010585712027 HEG1 other 1 1 1 1.62613633967705 -0.336434152068396 0.761479572284841 3.30306741635584 5.02162704637694 0.657768365880332 0.511650241491901 7.33812559149364 19.8282954095426 0.370083531636415 0.711819017792404 WFIKKN2 other 1 1 1 0.657768365880332 0.370083531636415 0.139995623509134 52.6321184510249 30.357027147334 1.73377051038567 0.0849998881441232 -67.7279897494307 99.4935838099497 -0.68072721029733 0.497086615650694 C11orf80 other 1 1 1 1.73377051038567 -0.68072721029733 8.11840825375308e-09 1329.23070495475 231.049367180026 5.75301599471188 4.50083535076982e-08 -603.230557593249 754.101710094812 -0.799932621181042 0.424966262886435 TOMM20 essential 8.7029336480233e-05 1 0.000532178771875023 5.75301599471188 -0.799932621181042 1.85925364533298e-12 446.938355800871 63.4426729177687 7.0447592329562 5.40338231923805e-11 -24.1259376216253 144.385415272516 -0.167094007217346 0.867509743278124 AGFG1 other 2.34098626483875e-08 1 7.09031827930417e-07 7.0447592329562 -0.167094007217346 1.0340350344971e-07 235.922491312291 40.6435358636121 5.80467437931529 3.495501772159e-08 -124.332461577043 161.961809288233 -0.767665304082745 0.443846434664817 STAT5B other 0.00102783082429011 1 0.000415650115727427 5.80467437931529 -0.767665304082745 0.0078321226152029 -44.6997861320829 17.230919175418 -2.5941614418256 0.010528977945111 139.47195238218 85.0042338794506 1.64076477155212 0.103174125647176 CD7 other 1 1 1 -2.5941614418256 1.64076477155212 4.48362960237596e-09 604.906749868165 91.8624678753867 6.5849172557473 6.58149277493748e-10 447.993232554057 369.494683456961 1.21244838589467 0.22717376954321 CNP other 4.88087918514647e-05 1 8.35125618211816e-06 6.5849172557473 1.21244838589467 1.63266794091159e-13 5337.98317542787 632.829141238574 8.43510961739273 2.03301530173493e-14 817.368108190735 2717.60466222145 0.300767848816757 0.763989455435377 JUP other 2.11903972050915e-09 1 2.8185724143253e-10 8.43510961739273 0.300767848816757 0.118730217047691 8.45011843388604 4.30565605434631 1.96256234293404 0.0514645797904631 16.2032263557971 18.3741155477011 0.881850683573417 0.379205671998411 HAP1 other 1 1 1 1.96256234293404 0.881850683573417 0.248217548868525 20.128974792165 20.2284386712896 0.995082968055969 0.321298431013456 -92.8483571137837 98.2126159589757 -0.945381163175282 0.345984673611044 TDRD12 other 1 1 1 0.995082968055969 -0.945381163175282 7.59613282229214e-08 1738.56583530723 324.116758637669 5.36401092808281 2.86778068027262e-07 -3055.23920548666 1383.1478174257 -2.20890288586293 0.0286299251984336 EIF1 essential 0.000763639232625028 1 0.00324116572484411 5.36401092808281 -2.20890288586293 1.67822355677908e-07 109.703071792583 18.8038207772677 5.83408409875963 3.02516073432382e-08 68.177121251262 81.0265360461945 0.841417202043454 0.401402210789747 ENDOV other 0.00163962441497316 1 0.000360599159531399 5.83408409875963 0.841417202043454 0.141636529625302 153.714859800425 450.314501002899 0.341350010843723 0.733296521268035 3875.65699643292 1971.98726544642 1.96535599612787 0.0511374592659874 RNF213 other 1 1 1 0.341350010843723 1.96535599612787 0.200733458142971 12.094643262465 6.71502151267781 1.8011324669073 0.0736259394043345 0.713709616403151 29.031562774286 0.0245839199891541 0.98041846653947 MARCH10 other 1 1 1 1.8011324669073 0.0245839199891541 0.0206245972760342 -1.86553859627173 38.3890225381523 -0.0485956263777671 0.961305772299391 -395.341444597356 144.925784291006 -2.7278889435128 0.00713004010448751 PLK3 other 1 1 1 -0.0485956263777671 -2.7278889435128 0.00375322293399963 342.220726002861 119.05879579462 2.87438423779459 0.00461341005880553 -280.982471682796 481.277440715853 -0.583826391831004 0.560180330096153 NET1 other 1 1 1 2.87438423779459 -0.583826391831004 0.0259736326344164 45.3385562597389 30.5741225051487 1.48290621430276 0.140129739007093 -99.5896724885305 77.6583488214653 -1.28240780289425 0.201614202974906 DPY19L1 other 1 1 1 1.48290621430276 -1.28240780289425 0.00354948412149743 58.0912908049655 18.4581410902673 3.14719074477093 0.00197513157094151 106.740781130621 75.4198927547226 1.41528683258354 0.158977601255425 PHOSPHO1 other 1 1 1 3.14719074477093 1.41528683258354 4.63832486803174e-18 173.458998201962 23.3357374043625 7.4331912120992 7.87434842449642e-12 -319.460940637047 98.1817983789581 -3.25376949609341 0.00141112123745934 ZNF791 other 6.47046319090427e-14 1 1.05169797557574e-07 7.4331912120992 -3.25376949609341 1.45187266679638e-11 285.713196983085 37.4430650722068 7.63060386301453 2.70864538482694e-12 270.199093239076 221.536855966285 1.21965752407445 0.224547984297075 PHC3 other 1.77462396062522e-07 1 3.65369175959305e-08 7.63060386301453 1.21965752407445 0.00321985444103286 158.431336601535 45.8686234488183 3.45402422591377 0.000721836415842769 36.8433903251944 271.387788546599 0.135759204651421 0.892197373205125 GPR160 other 1 1 1 3.45402422591377 0.135759204651421 2.95734475711009e-08 403.107371794872 65.2511409116807 6.17778273548488 5.35354688660574e-09 243.972756410257 279.655923479505 0.872403321105181 0.384320636518207 CBX2 other 0.000305851004929222 1 6.58914550803435e-05 6.17778273548488 0.872403321105181 0.0445085393608281 438.105491117309 218.684957679267 2.00336363217013 0.0469637827268704 -828.225253266774 714.26956757344 -1.15954156647115 0.248102791886903 SPTBN2 other 1 1 1 2.00336363217013 -1.15954156647115 1.61683288054045e-06 204.321115813145 37.9270879923486 5.38720810451793 2.75663995039419e-07 -92.443303663259 214.151460007181 -0.431672535224179 0.666607616845726 GOLIM4 other 0.0144722711137176 1 0.00311996509585614 5.38720810451793 -0.431672535224179 0.0847728602133263 59.8815619157197 27.1388492658726 2.20648861449779 0.028869996817494 -0.297727599597426 88.8459879012983 -0.00335105283457685 0.997330704221092 RBM4B other 1 1 1 2.20648861449779 -0.00335105283457685 0.00080433178502006 262.426546011116 115.896072503435 2.2643264809801 0.0249589813514539 -1450.34384146507 472.023487529202 -3.07260947767 0.00251264213573486 HOXB2 other 1 1 1 2.2643264809801 -3.07260947767 0.79910779460769 -29.7430409356727 49.4249613262671 -0.601781774584123 0.54818193851185 57.1046783625725 201.033365403309 0.284055725018632 0.776739585995563 C1QTNF1 other 1 1 1 -0.601781774584123 0.284055725018632 0.296003272997414 -8.42735504413708 9.72019586079637 -0.866994365630676 0.387276699152656 -22.3701829450312 14.2805153410631 -1.5664828902012 0.119261853768955 MARCH3 other 1 1 1 -0.866994365630676 -1.5664828902012 7.51571477976721e-17 37.214602852376 4.57249125737587 8.13880240718782 1.33059992654803e-13 -19.4401064854631 16.4552310578922 -1.18139371103752 0.239291464796838 SWSAP1 other 1.03566549665192e-12 1 1.82731287912841e-09 8.13880240718782 -1.18139371103752 0.00398719960390359 9.69099697166057 4.47234990658863 2.16686913458714 0.0317622904269452 -3.7930877160502 6.45376198780261 -0.587732817420135 0.55756144311055 SLCO4C1 other 1 1 1 2.16686913458714 -0.587732817420135 0.000155777343946513 386.95908241047 93.1392606449742 4.15462909766345 5.45195100925583e-05 -131.185128721415 304.915272690107 -0.430234692949416 0.667642418863427 RBM4 other 1 1 0.513410226541622 4.15462909766345 -0.430234692949416 0.289080767515807 -104.731110691349 83.5936447595869 -1.25285972387677 0.212155804823789 -352.254816773706 270.433024402145 -1.30255843402427 0.194670094139387 PIFO other 1 1 1 -1.25285972387677 -1.30255843402427 2.64072068296686e-11 280.496577102759 37.2950574388275 7.52101206876644 4.20605078803076e-12 80.8688105146529 138.973365190732 0.581901506117128 0.561483889735593 XXYLT1 other 3.19844089120946e-07 1 5.65124983879813e-08 7.52101206876644 0.581901506117128 6.53083376986104e-07 101.999159699172 19.2677438156484 5.29377807153181 4.09163422287892e-07 -31.3726687487454 65.3458163889073 -0.480102177651744 0.631840413240554 UBXN2A other 0.0060534298212842 1 0.00458303949304668 5.29377807153181 -0.480102177651744 2.02955362398883e-07 8.71266666666666 1.49099466432179 5.84352638889542 3.03625284997623e-08 7.77247619047618 9.08222070366564 0.855790279060182 0.393469726694367 TCAP other 0.00197008770280596 1 0.000361890977188667 5.84352638889542 0.855790279060182 0.000680764944574034 81.7580181216739 26.5877301922155 3.07502812502632 0.00250168562459129 -161.892017834029 87.0417581762048 -1.8599350613564 0.0648530755426864 CCS other 1 1 1 3.07502812502632 -1.8599350613564 0.132346884766487 14.137642080033 7.02789809899913 2.01164585497424 0.046109989729573 5.59539518171055 26.2988613108515 0.212761880279652 0.831811520710439 NRROS other 1 1 1 2.01164585497424 0.212761880279652 0.0356260708066024 10.4250791154055 4.75298308847329 2.19337601698771 0.0298733793499276 -16.0691575795783 17.7859782961826 -0.90347336041826 0.3677732325094 CEP19 other 1 1 1 2.19337601698771 -0.90347336041826 2.56563550321249e-12 151.81031242462 18.9220287492012 8.02294058616888 3.18752931184471e-13 146.525010749756 70.3844562922948 2.0817808145205 0.0391200952729919 FBXO45 other 3.21730692102846e-08 1 4.35799007515409e-09 8.02294058616888 2.0817808145205 0.0104038487931852 -36.7773485784925 164.886889964875 -0.223045923095081 0.823795340328177 -1570.98084054388 525.634815445951 -2.98873056802954 0.00326157844941961 GNG5 other 1 1 1 -0.223045923095081 -2.98873056802954 2.81711877533103e-10 65.2981017588456 14.9413318291725 4.370299950862 2.29683944610496e-05 -57.3906358902875 25.3480657136362 -2.26410316821191 0.0249918081149406 SLC25A30 other 3.26926633877165e-06 1 0.225044328929364 4.370299950862 -2.26410316821191 0.318399264179147 -0.349927204969558 75.068988841074 -0.0046614082642085 0.996286941418237 -369.622003241969 257.446980986014 -1.4357208689196 0.153163856551113 CD34 other 1 1 1 -0.0046614082642085 -1.4357208689196 1.39210878510772e-05 848.827987918885 182.473125308162 4.65179727965626 7.16976060852897e-06 -451.705321443981 597.372605028903 -0.756153391771499 0.450743124943579 CTSF other 0.113248049668513 1 0.0736621204920267 4.65179727965626 -0.756153391771499 0.00438775239568343 33.9638631737436 10.1616055176868 3.34237174574703 0.00104880092352592 58.5304377035084 65.3482945376644 0.895668940063517 0.371864681624294 MSRB3 other 1 1 1 3.34237174574703 0.895668940063517 1.59505482310878e-58 303.56644710615 11.3787228221562 26.6784288404545 8.08681926583094e-59 22.7650226867671 72.3286598987863 0.314744151469466 0.75339330388155 LEMD3 other 2.32925855818575e-54 1 1.18099908558195e-54 26.6784288404545 0.314744151469466 0.000248743431898569 42.9190318260093 16.3517230719531 2.62474062440705 0.00965614750594134 -53.6852421560497 36.171580720735 -1.48418291615537 0.140057524362237 C16orf91 other 1 1 1 2.62474062440705 -1.48418291615537 0.306105388683857 3.6200127312197 2.80050421352669 1.29262891794082 0.198075476326152 7.06396155451453 4.88825214386172 1.44508944027875 0.150464513885308 TLR10 other 1 1 1 1.29262891794082 1.44508944027875 0.0763866454522145 -22.7894288905419 14.8755586224403 -1.53200491282144 0.12757292117826 -59.0666477019682 25.9651390546253 -2.27484426629505 0.0242954600300488 TLR1 other 1 1 1 -1.53200491282144 -2.27484426629505 0.716379372363877 -4.14527170979747 6.4638801041071 -0.641297741145229 0.52228875414491 -8.86110085314698 11.2565069078334 -0.787198100236634 0.432383632831392 TLR6 other 1 1 1 -0.641297741145229 -0.787198100236634 3.50159038212253e-08 17.604648379848 18.3647432173827 0.958611191643818 0.339228546283352 -105.286022949381 26.6056953981129 -3.95727386087601 0.000114555576519419 FAM174A other 0.000360138570801302 1 1 0.958611191643818 -3.95727386087601 1.82444635781773e-08 134.849827295365 49.9646970119563 2.69890213210131 0.00771873928653629 -179.436313492382 72.2557079741951 -2.48335139912358 0.0140661540521429 RGMB other 0.000191548623107283 1 1 2.69890213210131 -2.48335139912358 2.33684502187648e-12 37.8273450356554 4.94679538207662 7.64683843053477 2.68012690337245e-12 20.4027701590785 8.84367269327864 2.30704718126724 0.0224779997680634 FAM53A other 2.93390892496592e-08 1 3.61575920533977e-08 7.64683843053477 2.30704718126724 0.00025957980882539 51.5881245956914 17.5777357444116 2.9348560784965 0.00386236277949631 -109.394615098112 56.7014667469505 -1.92930838255601 0.0555804128970489 CYB561D1 other 1 1 1 2.9348560784965 -1.92930838255601 0.140333646831291 44.8978138932833 38.3581392775918 1.17048988138775 0.243660118323241 -174.743880339422 125.575213038188 -1.3915475523524 0.166119658884974 ZDHHC24 other 1 1 1 1.17048988138775 -1.3915475523524 6.09670721310269e-07 145.677094354063 30.451473483568 4.78390953504014 3.99218940299212e-06 -253.806931282098 135.413546914385 -1.87430975013575 0.0627818511609255 TRMT10C other 0.0056638410009724 1 0.0419299652996262 4.78390953504014 -1.87430975013575 1.09161631958493e-06 86.425633940182 23.4098451323137 3.6918498798988 0.000316640820309561 -39.8770386324231 41.1771296108955 -0.968426867274198 0.334477787345878 CTU2 essential 0.00992825042662495 1 1 3.6918498798988 -0.968426867274198 9.30184996340304e-14 618.093655589124 76.8489812426059 8.0429648590637 2.44530786746207e-13 202.539079438422 113.383285096197 1.78632220143015 0.0760670921632742 MGA other 1.21491462372007e-09 1 3.34762647055557e-09 8.0429648590637 1.78632220143015 2.1677253405765e-15 63.0928673169778 9.21165874493074 6.84924062690646 1.7567854086576e-10 -106.078784240324 28.5528668780282 -3.71517104371586 0.000285331200157821 C12orf66 other 2.92642920977827e-11 1 2.27240192609861e-06 6.84924062690646 -3.71517104371586 0.514225023715221 5.64319840743199 5.29610567982053 1.06553734925154 0.288322467032389 17.603820267324 22.924599177478 0.767900896806893 0.44373736101617 SNX31 other 1 1 1 1.06553734925154 0.767900896806893 1.61087869098055e-15 330.898303874308 41.2050353411825 8.03053076242823 5.26784936835235e-13 40.769680414212 74.8996740978946 0.544323869299159 0.58715827112108 PIGG other 2.18000213250398e-11 1 7.18376618362209e-09 8.03053076242823 0.544323869299159 1.23489065836019e-18 3291.22184531886 322.094614627777 10.2181834027939 9.03590161216339e-19 -470.599276345554 1475.8567804506 -0.318865138256758 0.750290830448734 PRPF8 essential 1.72995832329679e-14 1 1.28815813383001e-14 10.2181834027939 -0.318865138256758 0.00385745782984042 130.010588181901 50.2403606607759 2.58777179287656 0.010635496696114 -150.588549514387 136.832470911805 -1.10053226774987 0.272911469070847 ADCY6 other 1 1 1 2.58777179287656 -1.10053226774987 0.000287033490405559 1.91524591658958 0.462099506347293 4.14466124780962 5.74321088374043e-05 1.31482143851168 5.90681150274686 0.222594108158054 0.824162519016953 REP15 other 1 1 0.539057773547877 4.14466124780962 0.222594108158054 1.44464793844598e-06 632.920666610625 124.213282662457 5.09543466724531 1.09018506475846e-06 -425.254203093483 566.969788773078 -0.750047377328046 0.454467097210259 PITPNA other 0.0129902742625063 1 0.0118906485013205 5.09543466724531 -0.750047377328046 4.57461700362476e-07 222.502025202519 80.3126975574794 2.77044641718423 0.00634190430611497 -785.730010501051 218.682237142104 -3.59302164075845 0.000448828831377457 DDX23 essential 0.00429876759830618 1 1 2.77044641718423 -3.59302164075845 0.00485787482439797 55.1184063154156 29.8983485497999 1.84352678287927 0.0673077817888502 -194.099813843551 90.8665413694291 -2.13609774201061 0.0343623542735591 ZNHIT2 other 1 1 1 1.84352678287927 -2.13609774201061 2.47698081248927e-08 634.514962429144 106.052636691085 5.98301920844635 1.56129273925319e-08 -220.746202633604 569.072746549756 -0.387905068327329 0.698639899662032 ZBTB4 other 0.000257457385650135 1 0.00018838558191829 5.98301920844635 -0.387905068327329 8.35607694348638e-19 148.349240483163 17.7279038592505 8.36812076943626 4.33137151023001e-14 -398.26580039043 94.2591102303132 -4.22522342315035 4.18508542338625e-05 TNK1 other 1.17185623055453e-14 0.602903406093023 5.97642640981537e-10 8.36812076943626 -4.22522342315035 0.00905892719778664 63.6039417134886 24.0228808200006 2.64764006407318 0.00896023544571794 -51.1125334869367 104.265647605954 -0.490214511303893 0.62468896705539 ZHX3 other 1 1 1 2.64764006407318 -0.490214511303893 0.343802027428493 63.1919856841565 118.97942354843 0.531116925931605 0.596107926672777 -544.122469848167 451.635118498132 -1.20478334735703 0.230147216999007 PHLDA3 other 1 1 1 0.531116925931605 -1.20478334735703 0.00171562977128946 31.8197104351817 11.8767250374924 2.67916537048161 0.00817755346765094 -112.020945466683 63.9544942041132 -1.7515726902501 0.0818252188237627 SLC16A11 other 1 1 1 2.67916537048161 -1.7515726902501 0.000256247872520663 27.5610631284683 7.74927619505738 3.55659837573569 0.000498624257494506 -53.0513414277968 41.7287625956108 -1.27133751704818 0.205513075534289 SLC16A13 other 1 1 1 3.55659837573569 -1.27133751704818 0.635744790586034 5.24828378332122 7.29166352530854 0.719764943226606 0.472774996197125 -7.46170697478068 22.3389146067359 -0.334022807559806 0.738822742256745 GLIS1 other 1 1 1 0.719764943226606 -0.334022807559806 0.545662215448271 45.6610418830044 48.8928403523915 0.933900373836045 0.35184627168008 -37.5908618899272 151.761142662285 -0.247697541218297 0.8047049328052 PODN other 1 1 1 0.933900373836045 -0.247697541218297 2.20007689013211e-09 58.7088815789474 10.7028123847891 5.4853695896216 1.72742017439144e-07 -83.3066259398496 49.1797265389515 -1.69392210576585 0.0923694417491029 SNHG11 other 2.43834521733341e-05 1 0.00198083271397466 5.4853695896216 -1.69392210576585 0.00136422928966465 17.0110825395675 5.99792484747902 2.83616133448512 0.00517600758942803 -21.0119879758067 16.6141948208187 -1.2647009501464 0.207876795143728 C11orf45 other 1 1 1 2.83616133448512 -1.2647009501464 8.66653455976362e-05 44.4939940788095 14.2274002001364 3.12734536548588 0.00210719662070655 -62.3472602034205 43.9999920475449 -1.41698344254358 0.158494593748688 EXO1 other 0.640714230453642 1 1 3.12734536548588 -1.41698344254358 5.70624416758943e-09 109.306963357864 19.039671046895 5.74101112821958 5.05211430266274e-08 -7.92430124973431 29.2261851593743 -0.271137037096085 0.786658402960925 RALGAPA1 other 6.17073244283121e-05 1 0.000596250530000257 5.74101112821958 -0.271137037096085 3.01941928126075e-05 27.9887678360114 9.7452886096247 2.87203067627663 0.00465763788393358 -43.6204796693106 19.5378359856042 -2.23261571555063 0.0270261789652165 LIG4 other 0.236601694879593 1 1 2.87203067627663 -2.23261571555063 8.45219790694883e-08 95.1403726708073 18.4082050565338 5.16836771312682 7.68943992974013e-07 -158.830039525692 75.3280060745034 -2.10851246173436 0.0367061439167433 GTF2IRD2B other 0.000846487620380925 1 0.00845607709073522 5.16836771312682 -2.10851246173436 3.57998284741417e-05 580.037034331501 362.332161678575 1.60084335777527 0.11146101270101 -2095.30765256217 715.189036653797 -2.92972563221274 0.00390886205700948 ATP2A2 essential 0.277627669816969 1 1 1.60084335777527 -2.92972563221274 5.57247516166335e-06 136.055049526664 29.4069917214073 4.6266224990168 7.7627782356328e-06 -11.168584378084 49.4504188855377 -0.225854191527391 0.821610457958057 ZWILCH other 0.0471542848179953 1 0.0795607141370006 4.6266224990168 -0.225854191527391 9.94525464753973e-12 8078.81886224582 1992.48643373572 4.0546418411988 7.90586124458157e-05 -15411.6460452247 3361.75098951851 -4.58441035438856 9.27983326626772e-06 RPL4 essential 1.22286851146148e-07 0.134789578192539 0.731213106511349 4.0546418411988 -4.58441035438856 2.35729656111549e-10 168.926415090947 27.5714120431891 6.12686846891748 7.01334314053042e-09 -52.7656189039574 46.5188721736149 -1.13428413971493 0.258415353015894 SNAPC5 essential 2.74483611576287e-06 1 8.59716965757397e-05 6.12686846891748 -1.13428413971493 4.75393308471448e-09 83.5487902788328 20.647531353106 4.04642999930666 8.2285854932198e-05 -95.4366496690896 40.8048290814544 -2.33885674361188 0.0206363256811718 C12orf76 other 5.16942683631852e-05 1 0.759663012734052 4.04642999930666 -2.33885674361188 0.233752032029178 -3.17829616597156 6.24086922546358 -0.509271393318687 0.611358087055403 29.4466848559001 21.4259989005486 1.37434361835733 0.17151554149401 CNTNAP2 other 1 1 1 -0.509271393318687 1.37434361835733 0.000312098496360364 11.3046575402331 2.8654176414013 3.94520413949315 0.000122420787788705 5.48876312425571 6.47940223539492 0.847109490173699 0.398292678859908 LINGO2 other 1 1 1 3.94520413949315 0.847109490173699 0.000596134872670442 206.820796778369 59.298016809146 3.48781979410936 0.000639242484610547 -239.318085718395 194.127276082462 -1.23278959323953 0.219582892971569 BBS1 other 1 1 1 3.48781979410936 -1.23278959323953 5.40336538771271e-09 107.013188518231 19.5892610468471 5.46284968393204 1.81488420578234e-07 -39.401629169899 32.4889999532183 -1.21276829778185 0.2270517483515 DENND4A other 5.85400606104796e-05 1 0.00207822390404136 5.46284968393204 -1.21276829778185 0.86305501521284 14.7756181102951 119.108031406645 0.124052240103355 0.901434639109753 -86.5545660888164 197.953617612083 -0.437246700176158 0.662541035888 IGDCC3 other 1 1 1 0.124052240103355 -0.437246700176158 0.00234796201980098 21.0528585008147 6.69969555200115 3.14236047554824 0.00204036013220909 -16.7174565453557 23.3931600097064 -0.714630111469303 0.47601080801322 ANKRD36C other 1 1 1 3.14236047554824 -0.714630111469303 0.882620861687234 -22.5547091260358 45.4208018484931 -0.496572235806623 0.620203436920151 -28.1460949086603 166.211765153974 -0.169338764211947 0.865753869098364 SLC26A9 other 1 1 1 -0.496572235806623 -0.169338764211947 0.105112039638374 1.25304959422904 8.77679197813309 0.142768519221026 0.886659624744538 68.1088067327924 32.2712789325651 2.11050844545437 0.0364303591522214 MFSD4A other 1 1 1 0.142768519221026 2.11050844545437 0.0988607432842906 38.9086725154608 20.4325531306922 1.90424917858235 0.0587923323511206 -46.5371062850569 66.891206419903 -0.695713364667469 0.487684835676622 PELI3 other 1 1 1 1.90424917858235 -0.695713364667469 0.000193722999749472 6.97570692376444 2.05905729500148 3.38781584208391 0.000893210909811961 -13.6146409759066 7.5566981937107 -1.80166530763897 0.0735416133829417 TMEM81 other 1 1 1 3.38781584208391 -1.80166530763897 0.461265335850384 130.94819419775 105.890447198584 1.23663840943247 0.218167033534819 17.067317939609 342.917085555439 0.0497709757213302 0.9603715518942 MRPL11 other 1 1 1 1.23663840943247 0.0497709757213302 6.31630620624075e-07 17.1167334551931 3.21360422906814 5.32633524077622 3.46822541209573e-07 -9.00836028308962 12.2610461883656 -0.734713836380254 0.463623891974096 IL20RB other 0.00586026889815017 1 0.00390036629844286 5.32633524077622 -0.734713836380254 0.054554112915491 17.765316250942 7.38561722020274 2.40539358069444 0.0173333380839657 3.7694819219528 27.57051926794 0.136721469962885 0.891428381966276 GOLT1A other 1 1 1 2.40539358069444 0.136721469962885 7.64573107306228e-21 782.663279194266 72.0842643905777 10.8576162330453 1.08837572878106e-20 -0.36844811420545 371.270896155572 -0.00099239697487912 0.999209483158984 AKIRIN1 other 1.08554089775338e-16 1 1.56149265808218e-16 10.8576162330453 -0.00099239697487912 5.5504301733698e-14 267.624524925689 31.5907255786182 8.47161690729978 2.00327326248783e-14 -64.1578355836207 121.220412914268 -0.529265938311856 0.597398195382035 MSL2 other 7.29437533384259e-10 1 2.77773870576562e-10 8.47161690729978 -0.529265938311856 1.4952401073479e-08 34.7150090193507 11.0620382352392 3.13821090481884 0.00207592433196625 -48.417396804573 19.5196750746797 -2.48044071529544 0.014315853479112 ZNF497 other 0.000157732878924129 1 1 3.13821090481884 -2.48044071529544 8.05758424381349e-11 93.5430321175829 18.522259121316 5.05030361063951 1.2252949522122e-06 -21.4711350027218 27.6475881463856 -0.776600652796136 0.438577916175726 TRAM1L1 other 9.57724463219671e-07 1 0.0133128296557856 5.05030361063951 -0.776600652796136 0.864299470063423 -9.92653150207108 19.7866709277077 -0.501677696987962 0.616606088836529 -3.71134607465545 39.6094388854256 -0.093698526893827 0.925469648933912 CMKLR1 other 1 1 1 -0.501677696987962 -0.093698526893827 2.81772358310434e-16 109.179917509216 16.8855382132192 6.46588317947383 1.22804990903544e-09 -197.849056466036 49.2954933929736 -4.01353233020357 9.26303851576017e-05 ANGEL2 other 3.85408231697012e-12 1 1.54488678556658e-05 6.46588317947383 -4.01353233020357 4.57123593379513e-05 148.563113807048 56.2220439671822 2.64243530337971 0.00908142155231699 -95.5703969629434 85.0374097215946 -1.12386298307807 0.262819988006206 UGT8 other 0.349470987138638 1 1 2.64243530337971 -1.12386298307807 0.537503325053516 0.239990415196279 3.77657028895556 0.0635471861593895 0.949413732799215 -15.8463599529473 14.4890170006982 -1.09368081714472 0.275813900227636 KY other 1 1 1 0.0635471861593895 -1.09368081714472 4.50812474439141e-12 411.986863129262 77.2811250319836 5.33101534118138 3.34560940620526e-07 -320.251524114776 159.478909786198 -2.00811207290114 0.0463462852352746 IQCK other 5.60720555707404e-08 1 0.00376648706950588 5.33101534118138 -2.00811207290114 0.383115522309938 -42.6767038777908 32.2233849515908 -1.32440164004818 0.187344644231277 26.6339502546024 123.021666236188 0.216498045177409 0.828887943872652 SLCO2A1 other 1 1 1 -1.32440164004818 0.216498045177409 5.25119861821084e-14 156.941518769554 26.4206876740227 5.94009969406899 1.95188530069093e-08 -263.196670739659 91.7353006145804 -2.86908822423183 0.0047192542625359 ZNF266 other 6.90540884847041e-10 1 0.000234694688555078 5.94009969406899 -2.86908822423183 0.0780085448751774 18.1644695014772 7.97825742326408 2.27674647956466 0.0241970162335683 17.1125883540894 13.7922121061055 1.24074283533634 0.216612393698987 BRSK2 other 1 1 1 2.27674647956466 1.24074283533634 1.38146204972769e-11 377.022140077821 86.1658861579804 4.37553835849342 2.22348319662818e-05 -176.846949416342 125.247547937925 -1.41197933474906 0.159973484274893 TMEM167A other 1.68952808681696e-07 1 0.218145936421191 4.37553835849342 -1.41197933474906 0.00473867467061892 412.567888680761 124.07908992596 3.32503960922785 0.00110819995938253 296.066984211936 207.354212423302 1.42783202111916 0.15539156314315 SH3PXD2B other 1 1 1 3.32503960922785 1.42783202111916 3.48429831243901e-22 2117.65813237062 179.233522824683 11.8150784462458 5.00365118353605e-23 271.264672158701 1513.49593626686 0.17923052560537 0.85800518740833 KIAA1551 other 4.97174526201923e-18 1 7.21226281594887e-19 11.8150784462458 0.17923052560537 7.33806780792445e-15 300.236857307914 52.945064035307 5.67072422667575 6.83425897389862e-08 -124.124329454485 80.0808861686804 -1.54998696184546 0.123197277393422 LARP7 other 9.81393188631816e-11 1 0.000800906809151179 5.67072422667575 -1.54998696184546 0.00294614984625928 19.3637745148372 6.06228685426168 3.19413696189992 0.00169319111262296 8.25742376013959 10.5168484730176 0.785161427525092 0.433534674618083 FGFBP3 other 1 1 1 3.19413696189992 0.785161427525092 8.9798801238979e-21 507.923361641752 50.3844004122149 10.0809646931635 1.07900878775993e-18 -13.0164675481349 110.092224111793 -0.118232397003056 0.906036602045819 NR1D2 other 1.27433478838235e-16 1 1.53780332431545e-14 10.0809646931635 -0.118232397003056 4.46967642992942e-05 3245.49651456891 1513.24121263286 2.14473177671532 0.0335326080678685 -9156.79146532046 3306.50140427173 -2.76932937439271 0.00630331853729361 RPL15 essential 0.342243124239696 1 1 2.14473177671532 -2.76932937439271 0.253953912162019 45.2945500057989 30.0940282647338 1.50510093256203 0.134415030924336 11.208054664244 51.9903652773822 0.215579456009706 0.829610391749631 HRAS og 1 1 1 1.50510093256203 0.215579456009706 0.270359509604576 -7.59712564842409 5.47760375718244 -1.38694326665423 0.167544368455118 -27.0085773299907 31.1371720060181 -0.867406241156731 0.38712367136084 WDR49 other 1 1 1 -1.38694326665423 -0.867406241156731 3.71619553073375e-17 636.02211654157 104.541419843178 6.08392460610983 9.12032862663077e-09 -464.722626482554 181.854543019454 -2.55546338720193 0.0115864427025122 SRP72 essential 5.1350389843679e-13 1 0.000111204166944509 6.08392460610983 -2.55546338720193 5.62207300536573e-09 13.6332903655038 2.6564678078887 5.13211201920766 8.57609291690428e-07 -7.40648259802902 7.98182374155858 -0.927918585757042 0.35491133278085 PCP2 other 6.08139636990411e-05 1 0.00940883153913568 5.13211201920766 -0.927918585757042 7.2274929074698e-41 75.8325878234099 4.790816882268 15.8287385402028 4.0939299227046e-34 -83.0049797167707 19.3439229177156 -4.29101067399068 3.13075865959763e-05 THAP6 other 1.0529011667602e-36 0.451799782166534 5.9538022865893e-30 15.8287385402028 -4.29101067399068 3.88227128979134e-13 126.6428980691 18.2698791963107 6.93178628650557 1.10957585419989e-10 15.9683149028822 31.7812837940188 0.50244398578661 0.616082388414982 CEP135 other 4.98949506163983e-09 1 1.4437801014849e-06 6.93178628650557 0.50244398578661 0.000111066908315472 607.466302510758 150.556522610891 4.03480561304366 8.53515433398519e-05 -78.2630503719966 496.670743646263 -0.157575318001289 0.87499522699182 FZD4 other 0.810677363794628 1 0.786343768790056 4.03480561304366 -0.157575318001289 1.161430600822e-11 93.7500533705714 13.5271345821416 6.93051827061287 1.09731761052034e-10 -49.8689956537521 55.1841612888949 -0.903683130974531 0.36758408088257 BTC other 1.42519149026867e-07 1 1.42804913833117e-06 6.93051827061287 -0.903683130974531 0.881285594995703 0.824317329416746 3.23782291400971 0.254589998066298 0.799377242713178 5.37007952218194 10.6802898672968 0.502802788024061 0.615816603075004 ADGRE1 other 1 1 1 0.254589998066298 0.502802788024061 2.178980512162e-12 130.206209808533 23.5239567888359 5.53504714267826 1.30944051026854e-07 -118.892805102147 52.8247207336118 -2.25070390247226 0.025820129327456 DENND6A other 2.73767111548034e-08 1 0.00151227284530913 5.53504714267826 -2.25070390247226 8.63200333960619e-10 114.968766801524 28.5692241270739 4.02421732876437 8.91412001792416e-05 -185.916492852322 64.6380819379103 -2.8762687146396 0.0045911061763842 PDE12 other 9.77919658343986e-06 1 0.820009900448843 4.02421732876437 -2.8762687146396 2.26515387967112e-09 41.8911369090807 8.43087049388724 4.96877955122827 1.76401123858497e-06 -87.6210303064129 28.808351224412 -3.04151492821857 0.00276488134109821 GLMN essential 2.50797837557187e-05 1 0.0189772329046971 4.96877955122827 -3.04151492821857 0.167129710691102 -24.4542235932478 22.4116999093316 -1.09113649085877 0.276906066728025 -96.0879017589885 50.7066376273903 -1.8949767970236 0.0599574501522028 DNAH12 other 1 1 1 -1.09113649085877 -1.8949767970236 0.610025885801182 -1002.83033307822 1180.67272317498 -0.849371983780133 0.39702790038219 -2824.99493276165 3651.55601201941 -0.773641407515846 0.440360422219709 AMY1B other 1 1 1 -0.849371983780133 -0.773641407515846 3.10444453817137e-06 334.427994204012 235.532683578877 1.41987935229387 0.157638120932579 -1423.63218504227 456.126497155499 -3.12113458420051 0.00214709025921675 NDUFA11 other 0.0269652052585565 1 1 1.41987935229387 -3.12113458420051 3.32502786495929e-11 157.373335062437 20.8925737064664 7.53250113047241 4.13254139949808e-12 2.36480842073416 82.6636835875474 0.0286075857995082 0.977215088189887 RSRC1 other 4.01064861071389e-07 1 5.55330913264552e-08 7.53250113047241 0.0286075857995082 0.885191006567172 3.42876442631554 10.2698988524609 0.333865452384073 0.738944292894677 -14.210306930214 40.1321871212994 -0.354087527980058 0.723767242618794 PQLC2L other 1 1 1 0.333865452384073 -0.354087527980058 3.19017655338949e-06 157.411460548189 36.7458943373272 4.28378362772048 3.27986033515588e-05 -15.7985657401326 63.4821118740194 -0.248866417227658 0.803806821393131 PTDSS2 other 0.0276779717772072 1 0.316276932119081 4.28378362772048 -0.248866417227658 0.000436787495816865 19.4719420578589 83.3661864054995 0.233571222307638 0.815626064350383 -432.589922384095 150.566166529912 -2.87308850556512 0.00463517804338089 C19orf70 other 1 1 1 0.233571222307638 -2.87308850556512 0.00176677837203876 17.4827506448357 4.81538752804597 3.63060097302907 0.000385841997839476 6.36025989682629 19.3174023453031 0.329250267874281 0.742419772242668 C3orf33 other 1 1 1 3.63060097302907 0.329250267874281 0.0890037590997145 441.574536376606 225.148496951736 1.96125909057818 0.051676117159713 -17.3310938290918 482.03693303127 -0.0359538712523663 0.971366314476912 SEZ6L2 other 1 1 1 1.96125909057818 -0.0359538712523663 0.125066944976577 -69.6793534576008 40.6132400442278 -1.71568073322197 0.0882447296946531 -154.659113423896 86.9075584161552 -1.77958184814391 0.0771295901392926 ASPHD1 other 1 1 1 -1.71568073322197 -1.77958184814391 1.08184924387565e-05 27.2684352261988 27.5077106122944 0.991301515801587 0.323103515778906 -229.447774450302 58.8632663714904 -3.89797897048798 0.000144742793466183 KCTD13 other 0.0890902852331597 1 1 0.991301515801587 -3.89797897048798 0.450579803341617 -3.79559329467715 4.29346032119833 -0.884040613101038 0.378108145588975 0.784232257516897 8.45299090872898 0.0927757128789834 0.926207214252221 AMZ1 other 1 1 1 -0.884040613101038 0.0927757128789834 0.143658577023587 3.45028209550132 1.92797996334251 1.78958400040612 0.0754859556970155 -5.63954590618897 8.11114722868147 -0.695283385591526 0.487925523227842 GPR171 other 1 1 1 1.78958400040612 -0.695283385591526 0.0238192872204094 -10.8471899703943 13.118436129252 -0.826866088573384 0.409626368877139 -77.5285728592261 29.0019731444129 -2.67321717985114 0.00834477232316557 CD164L2 other 1 1 1 -0.826866088573384 -2.67321717985114 2.57990662015547e-06 43.0665650741352 10.834551137537 3.97492840519513 0.00010710479529712 -7.47849670510709 19.1206043119269 -0.391122402990276 0.696237036516251 FUT1 other 0.0226103016190425 1 0.976153104337948 3.97492840519513 -0.391122402990276 9.40778349994758e-14 257.480096902907 30.060652689465 8.56535284056365 1.11954891909697e-14 14.5808949268479 122.731516363777 0.118803184046305 0.905588149905168 DHX36 essential 1.22846836942315e-09 1 1.55606104265287e-10 8.56535284056365 0.118803184046305 2.74497787271124e-05 137.432539669168 29.941874275967 4.58997784849691 9.26380014868738e-06 185.240265932533 123.16475163913 1.50400389289367 0.134669068243332 ZIC4 other 0.216523854599463 1 0.0943332769140836 4.58997784849691 1.50400389289367 3.22926672323395e-14 202.987205064727 33.1182988080845 6.12915555358103 7.01294531166814e-09 -154.82049748285 64.1940370046553 -2.41175823654186 0.0170447236352169 FBXW8 other 4.26392378135811e-10 1 8.59716965757397e-05 6.12915555358103 -2.41175823654186 2.15496251877957e-12 996.592588443627 139.328046872404 7.15284977299868 3.16241221807375e-11 -22.2991464775507 258.07302854971 -0.0864063424328569 0.931254924091696 CTBP2 other 2.70792590109841e-08 1 4.17438412785735e-07 7.15284977299868 -0.0864063424328569 0.617984201339966 -2.36508718353016 71.7666261942589 -0.032955251053997 0.973754083777609 -295.410747709586 302.397256272845 -0.976896256767108 0.330193379382472 CHST2 other 1 1 1 -0.032955251053997 -0.976896256767108 0.0328416408554031 59.9600914035595 22.9929533331101 2.60775945285882 0.0100224150699794 59.0321564588628 49.1016875881854 1.20224292398999 0.231139005093248 ZDHHC14 other 1 1 1 2.60775945285882 1.20224292398999 3.46459997587143e-10 158.972524610237 22.5265365473209 7.05712235328709 5.2365473481808e-11 44.6090933013969 94.0232072087914 0.474447688242928 0.635844149233415 ATR ts 4.00507757210738e-06 1 6.87611032289621e-07 7.05712235328709 0.474447688242928 1.23515529753199e-05 5008.82687735981 1379.40242984435 3.63115706409551 0.000382885639063517 -11712.7098832331 4646.6799546134 -2.52066206358893 0.0127247740522227 LRRC75A-AS1 other 0.101060406444067 1 1 3.63115706409551 -2.52066206358893 0.00122791327264231 457.496972377194 140.573998750316 3.25449212830452 0.00139300728691581 -453.434242754116 631.755401918125 -0.717737025085036 0.473992877868768 UBE2C other 1 1 1 3.25449212830452 -0.717737025085036 0.00200750449398342 82.9807765142765 23.0975910335515 3.59261606085842 0.000438331824104501 40.6669376368323 94.8854946895881 0.428589614986692 0.66881311103687 GK5 other 1 1 1 3.59261606085842 0.428589614986692 8.54356277661289e-09 128.880176660106 23.3890777821253 5.51027183973026 1.57731743772705e-07 -96.1374110089409 84.8324910387988 -1.13326167641325 0.258961905681438 VCPIP1 other 9.14673830864176e-05 1 0.00181344185815479 5.51027183973026 -1.13326167641325 0.00814738659104341 319.176666371099 104.629966354507 3.05052823289328 0.00272982033171562 147.689105568505 261.893008591335 0.563929164672597 0.573698201614188 DES other 1 1 1 3.05052823289328 0.563929164672597 1.86707623577746e-09 94.0438173819963 16.4529980281149 5.71590765532786 5.44178216498137e-08 14.0936779622912 34.7892877418948 0.40511545010216 0.685951227311213 PDIK1L other 2.07749572754958e-05 1 0.000641096356856456 5.71590765532786 0.40511545010216 0.607216468798605 17.360250895792 18.313616055768 0.947942276551345 0.34463440917153 -11.1421792176256 71.616422706457 -0.155581342889681 0.876565463385162 SPSB4 other 1 1 1 0.947942276551345 -0.155581342889681 0.000903560327129756 3.59922868495249 1.56341910571564 2.30215216879097 0.0226662480932741 -4.18448715791353 2.60922926793361 -1.60372536416758 0.110823556285541 RAG2 other 1 1 1 2.30215216879097 -1.60372536416758 6.0930371005884e-07 33.7176870164257 18.5859059749144 1.81415353450807 0.0716005536589361 -118.225003520026 31.0184835681735 -3.81143724386743 0.000199321552166118 TRAF6 other 0.00566104077015668 1 1 1.81415353450807 -3.81143724386743 0.00704007441579996 45.7092423176164 14.5600585766726 3.13935840827244 0.00208011077040218 27.7288164307865 35.1844837474698 0.788097862393123 0.432021105368882 ZNF654 other 1 1 1 3.13935840827244 0.788097862393123 8.2880623543331e-06 26.5532340116279 6.53324240349385 4.06432707860767 7.59415031033925e-05 -61.0019985465127 26.8823165134033 -2.26922402747909 0.0246164629160233 TVP23C other 0.0690727116610121 1 0.703522084749828 4.06432707860767 -2.26922402747909 2.96298817269121e-08 125.785023085194 23.9259289903421 5.25726809337133 4.91135166418864e-07 -213.077461893618 97.8681170500589 -2.17718975613509 0.0310194385953758 MRPS22 essential 0.000306372977056271 1 0.005478121646236 5.25726809337133 -2.17718975613509 6.09895783286153e-12 3815.35615680047 554.194322699511 6.88450963953521 1.50872667202592e-10 -328.071398575242 1559.78901961727 -0.210330624494165 0.833696984510133 MARCKSL1 other 7.55416917178229e-08 1 1.95530976694559e-06 6.88450963953521 -0.210330624494165 4.76377797479941e-14 226.66202367673 32.8938511921814 6.89071104360701 2.5471116688842e-10 -200.435266812997 107.825643479363 -1.85888310373365 0.065433748411494 SH3BP5L other 6.27056094822846e-10 1 3.27533089501819e-06 6.89071104360701 -1.85888310373365 0.00392063496103678 59.2575348171855 33.8333849348935 1.75145155978973 0.0818461397381402 -106.109156878758 78.7359678653062 -1.34765799869609 0.179734912634412 TMEM51-AS1 other 1 1 1 1.75145155978973 -1.34765799869609 0.0120298108367316 116.808283020098 40.4000216021255 2.89129258816914 0.00438438642032641 141.290884184128 156.658468592614 0.901903902504953 0.368498305715707 YPEL2 other 1 1 1 2.89129258816914 0.901903902504953 0.91835309972845 0.435592448246187 7.80839482209977 0.0557851463931291 0.955590834786288 7.09669990383154 18.339556340199 0.386961373120901 0.699360063584468 CADM2 other 1 1 1 0.0557851463931291 0.386961373120901 0.000942751215842383 260.547583160084 89.5944925064932 2.90807588581632 0.00416389511752589 -63.2349965349962 123.831726875459 -0.510652626193233 0.61031158641395 ABO other 1 1 1 2.90807588581632 -0.510652626193233 3.19823263860963e-07 1153.6723683219 198.923740093445 5.7995710707026 5.26927909412504e-08 176.219041519101 806.263241568407 0.218562663450099 0.827352967966071 PSMD2 essential 0.00304439764869251 1 0.000621248005197342 5.7995710707026 0.218562663450099 0.306969836677636 4.22818268902924 3.00399116862306 1.40752167755783 0.161774597316239 11.1932208710147 10.4312613361233 1.07304577177573 0.285334395852217 FAM182B other 1 1 1 1.40752167755783 1.07304577177573 0.385067127746776 12.8282550923507 9.48454904319527 1.35254243864703 0.178159102012256 11.9329951929093 36.4955432449521 0.326971299284875 0.744127902739232 PPM1E other 1 1 1 1.35254243864703 0.326971299284875 5.384325049e-07 110.352497927812 19.6293154091922 5.62182101756515 1.20271349585647e-07 -23.0320322507725 79.5601141630936 -0.289492197102158 0.772692155335682 FAM131A other 0.0050251905682317 1 0.00139226114280345 5.62182101756515 -0.289492197102158 0.0215741923008505 39.0917429293151 50.9507080473193 0.767246313692236 0.444125208819275 -214.484533521055 111.753726731048 -1.91926067966614 0.0568250464861731 CSRP2 other 1 1 1 0.767246313692236 -1.91926067966614 2.08382764248285e-07 194.264792642721 33.2831037168918 5.83673909426084 3.27378648095034e-08 117.897194748106 145.34327687836 0.811163730997863 0.418583070609465 PARL other 0.00202027089938712 1 0.0003896133290979 5.83673909426084 0.811163730997863 0.0245611160629776 57.3626035692064 35.7775436717701 1.60331307524803 0.111237771237643 -203.081862596769 120.517902659885 -1.68507630911807 0.0943188730162316 DDIT3 og 1 1 1 1.60331307524803 -1.68507630911807 2.90957907833336e-06 79.1270703540495 17.3042035566966 4.57270801830274 9.87350271183586e-06 -13.8595831433924 35.5449616912203 -0.389916952613168 0.697140218520025 PCCA other 0.0253453433513619 1 0.100344408060388 4.57270801830274 -0.389916952613168 2.75865102771112e-13 429.810324972615 65.1228567861597 6.59999186436122 8.94509450125907e-10 -742.01767056147 221.865180084865 -3.34445301546481 0.00107146925852729 DCTN2 essential 3.55921155595288e-09 1 1.13092829779418e-05 6.59999186436122 -3.34445301546481 1.21719777728284e-55 115.072615815116 4.51509528237703 25.4861987662272 3.14574661402854e-55 -50.3816692197514 29.4190227131629 -1.71255414263674 0.0889470203619077 ZNF408 other 1.77686531527749e-51 1 4.59216090715887e-51 25.4861987662272 -1.71255414263674 1.15510281760727e-09 1642.54715604363 269.296397432893 6.09940263479741 8.85579905362372e-09 -1331.07229012368 872.146864337099 -1.52620200169544 0.129093779678721 CTDSP2 other 1.29949066980817e-05 1 0.000108023036856102 6.09940263479741 -1.52620200169544 7.09702139259974e-06 187.862630909175 51.9503802558064 3.61619356747977 0.000412725059383294 -970.049227249881 338.15387713103 -2.86866214718574 0.00474260667791308 CKAP5 essential 0.0594375541630228 1 1 3.61619356747977 -2.86866214718574 9.88540263389155e-32 811.276281749957 54.8884464274273 14.7804562627331 1.16203488481523e-30 -843.500280931497 357.636849534789 -2.35853850638913 0.0196909090569013 ARHGAP1 other 1.43466848425668e-27 1 1.68692604228627e-26 14.7804562627331 -2.35853850638913 3.24676784352093e-07 518.760229895887 103.23633588883 5.02497715973291 1.52241100911421e-06 -33.6637207330282 154.077638615059 -0.218485440428719 0.827371355358162 MED16 other 0.00308865024954146 1 0.0164466061314608 5.02497715973291 -0.218485440428719 1.10547803186459e-57 941.072066762552 35.093296253492 26.8162916348706 1.19116410414313e-57 -199.52672617164 228.843334174211 -0.871892235321774 0.384728695771939 ATG13 other 1.61421902212868e-53 1 1.73945694128021e-53 26.8162916348706 -0.871892235321774 0.00752221982446012 -111.251102941175 151.988023016277 -0.731972827419832 0.465358490145046 -815.72775735294 268.725328513364 -3.03554473955132 0.0028438408967721 CHST1 other 1 1 1 -0.731972827419832 -3.03554473955132 1.50954727849029e-06 771.267813863306 150.295356965484 5.13168090775039 8.70587980688008e-07 283.002520601067 220.269455485157 1.28480147180523 0.200829062731625 GOLGA8A other 0.0135542250135643 1 0.00954512662026332 5.13168090775039 1.28480147180523 0.648529393463954 36.1976470588222 279.673602911913 0.129428185863587 0.897196983073664 -359.948382352942 494.482258059053 -0.727929822529559 0.467822360128323 TP53I11 other 1 1 1 0.129428185863587 -0.727929822529559 3.89329234847678e-09 83.4520440870493 16.5589335944473 5.03969918177781 1.29273394353594e-06 -28.5344992408479 37.9864084302875 -0.751176550244656 0.453692760146241 CENPS other 4.25326248770621e-05 1 0.0140248705534214 5.03969918177781 -0.751176550244656 6.89733680311774e-06 112.667185364865 37.3535828037076 3.01623504114528 0.00299197987297735 -81.681451744722 50.8763846537343 -1.60548852479687 0.110421801059351 DOLK essential 0.0578134770837329 1 1 3.01623504114528 -1.60548852479687 0.00132420147422465 197.391043956404 87.7786376635489 2.24873669961698 0.0259387562701159 -135.902698320332 119.556395905033 -1.13672461679326 0.257407755825919 PHYHD1 other 1 1 1 2.24873669961698 -1.13672461679326 0.238518583672896 4.64603920521752 17.9981537334836 0.25813976666807 0.796650540560094 -113.506832606885 73.4634097181004 -1.54507983011464 0.124420171061646 CCNE2 other 1 1 1 0.25813976666807 -1.54507983011464 0.185060386985754 288.50817547358 177.415034710407 1.62617658613042 0.105956677460981 -7.4701441131146 289.96340647418 -0.0257623684448603 0.979480230401579 PHYKPL other 1 1 1 1.62617658613042 -0.0257623684448603 5.25086217661806e-14 75.1466238422467 10.1750095055532 7.3854106771334 1.24272515605809e-11 -3.56251867343887 27.399988131064 -0.130018986008244 0.896738031642669 ZNF519 other 6.90540884847041e-10 1 1.65456421935548e-07 7.3854106771334 -0.130018986008244 8.32451595083767e-26 297.81662591687 22.9632528263243 12.9692699971262 1.05075092566382e-25 60.8475403954501 79.9878976904731 0.760709334190906 0.448119201580889 LSM1 other 1.20081142590833e-21 1 1.51886046304705e-21 12.9692699971262 0.760709334190906 4.2812296704221e-11 -36.7304655921228 53.163675882658 -0.690894017057693 0.490665523119174 -518.973826820469 83.607500529514 -6.20726398389662 4.71780277159293e-09 TMEM9B other 5.14218495714398e-07 6.89931477317751e-05 1 -0.690894017057693 -6.20726398389662 0.00473303884690267 40.8397384075868 12.2849427895311 3.32437351213303 0.0011060348641645 37.8544850387203 19.3198333961669 1.95935877201874 0.0518647801693917 NRIP3 other 1 1 1 3.32437351213303 1.95935877201874 1.31824977441989e-16 224.408474158135 34.1940119704871 6.56280036258459 8.89656375315929e-10 -242.139403337504 91.5033148817309 -2.64623640848938 0.00904447730778515 PTPN2 other 1.81022059023339e-12 1 1.12505945222452e-05 6.56280036258459 -2.64623640848938 0.00244415379360726 130.213056761985 37.2834562768559 3.49251570978457 0.000623683586080442 104.13387655202 58.6335790115327 1.77601091912772 0.0776931281952146 SCUBE2 other 1 1 1 3.49251570978457 1.77601091912772 5.4141438598491e-25 534.111032328536 70.2603110538889 7.60188823984679 2.9453151811537e-12 -321.182379531862 141.175677419552 -2.27505463690717 0.0243196402365078 SMAD2 ts 7.79853281572664e-21 1 3.96940126964084e-08 7.60188823984679 -2.27505463690717 8.55043621274966e-13 540.328783411015 206.387702659788 2.61802799511606 0.00971522050566701 -1445.72622784489 326.660853204422 -4.42577129663029 1.79678679720452e-05 EIF3F essential 1.08778649498601e-08 0.260210663971159 1 2.61802799511606 -4.42577129663029 0.000213798167757986 35.6060079697558 9.16361475900657 3.88558542738388 0.000154762580765632 -11.0324920813323 41.6145044821697 -0.265111701283367 0.791299926591666 ZNF25 other 1 1 1 3.88558542738388 -0.265111701283367 2.08918712047232e-09 103.1152200489 20.6507116078566 4.99330105455879 1.59998533524666e-06 -72.4271504778839 33.2994246614762 -2.17502708272537 0.0311637931026184 ARL10 other 2.32025121599655e-05 1 0.0172654417526467 4.99330105455879 -2.17502708272537 0.0553033713358948 252.811786878566 131.726262330133 1.9192208327066 0.0568178601301396 -126.64265207083 212.409568817536 -0.596219147639338 0.551909907402574 CLTB other 1 1 1 1.9192208327066 -0.596219147639338 0.686779698581896 -11.1610395952307 25.6437099239039 -0.43523498075553 0.663993426941091 10.0233447728599 37.3121584624627 0.268634814652808 0.788565645235787 PCSK1 other 1 1 1 -0.43523498075553 0.268634814652808 0.146525512245108 -28.9334354214836 23.6677375591968 -1.22248420868773 0.22342928857797 -87.5254763809295 44.6676101522491 -1.95948420080232 0.0518975957478161 LPL other 1 1 1 -1.22248420868773 -1.95948420080232 4.63248343882846e-06 1.00853216858153 3.21616558115336 0.3135821658224 0.754257305978017 -16.9603844223492 4.67959121989804 -3.62433033685337 0.000391600104866859 RFESD other 0.0395011862828902 1 1 0.3135821658224 -3.62433033685337 2.26783392422914e-06 281.040916937929 52.9205437234088 5.31062035958663 3.81265231195707e-07 104.561625912916 229.753703148467 0.455103114683413 0.649684429067009 CCDC14 other 0.0200181700491706 1 0.00427665209832225 5.31062035958663 0.455103114683413 0.137848692454157 38.7460808284194 19.6779015616938 1.96901487218763 0.0507940431132401 -1.98820652955558 64.4206608373664 -0.030862870757798 0.975419927339505 TBC1D10C other 1 1 1 1.96901487218763 -0.030862870757798 5.87709755953631e-06 163.245658590157 35.4548830749532 4.60432088423613 8.76122413522366e-06 28.5698057519393 68.8811896313888 0.414769342760018 0.678903360671132 PPP2R2D other 0.0495968263049269 1 0.0894433371964983 4.60432088423613 0.414769342760018 0.163451484234606 -7.6071228474474 17.5243868576523 -0.434087817693069 0.664832217099242 -42.7416056182189 25.4283939798586 -1.68086138873237 0.0948169545455802 MCTP1 other 1 1 1 -0.434087817693069 -1.68086138873237 0.525511867471501 63.342154465698 94.2537724934059 0.672038400055865 0.502593044673897 -243.317675823386 308.563913250786 -0.788548710249306 0.431620300942246 POLD4 other 1 1 1 0.672038400055865 -0.788548710249306 0.522064009218707 -3.33623669742089 10.5860859769285 -0.315152994666011 0.753074912098149 31.4214233464687 36.9594101070371 0.850160304384459 0.396564402755568 LRRC25 other 1 1 1 -0.315152994666011 0.850160304384459 1.74915948881481e-08 102.576001474111 16.3838562996128 6.26079718951971 3.58960302139302e-09 47.6921245623733 64.500524941145 0.739406766160292 0.460778362954296 DPP10 other 0.000183941611843765 1 4.44536438169311e-05 6.26079718951971 0.739406766160292 0.0763384553386593 58.874658420825 51.6096449336711 1.14076852294742 0.255784330208627 -297.209981303035 168.957417628363 -1.7590821727447 0.0806025397500658 CLCF1 other 1 1 1 1.14076852294742 -1.7590821727447 4.49345951751991e-06 36.7610889118597 8.0976851337925 4.53970342196336 1.124313767916e-05 -29.220484852225 31.1224726061808 -0.938886997250404 0.349249528439383 LIPT2 other 0.0383966115772076 1 0.113611906247912 4.53970342196336 -0.938886997250404 0.000969493688379988 164.799580608196 43.8117328600679 3.76153988554975 0.000239469626761711 99.4457895817257 168.247424011108 0.591068720167508 0.555340907769704 KCNE3 other 1 1 1 3.76153988554975 0.591068720167508 0.127144201155236 11.8237451459802 7.49542729385978 1.57746112161826 0.116796079981646 -24.8503523658853 24.5382048494868 -1.01272087825141 0.312824280356086 CABP4 other 1 1 1 1.57746112161826 -1.01272087825141 2.14174791131769e-09 77.9258753753381 13.8458959618573 5.62808471116703 1.00087616596571e-07 -120.166513636251 51.4051538742088 -2.33763552056093 0.0208652210579908 ALG10B other 2.37648348239811e-05 1 0.00116311819246876 5.62808471116703 -2.33763552056093 0.000609784693394842 9.31146267172253 2.86388459370741 3.25134004777354 0.00141110802657408 -12.2649655000932 11.0077937117392 -1.11420742623595 0.266926124842762 UCP3 other 1 1 1 3.25134004777354 -1.11420742623595 2.28429705309118e-14 5238.13400378202 645.26729420391 8.11777390677224 1.3748509716492e-13 -1841.95194336349 2461.42611502473 -0.748327131218799 0.455396831231725 UCP2 other 3.02829260328297e-10 1 1.88725792878286e-09 8.11777390677224 -0.748327131218799 6.21898099961735e-15 201.266394214625 22.9792248211216 8.75862418255419 3.33908820027818e-15 52.8993101339603 86.0005671151968 0.615104201151398 0.539393768671601 PAAF1 other 8.32970315088748e-11 1 4.66437230696858e-11 8.75862418255419 0.615104201151398 2.16180579880782e-09 186.016412641993 30.3605275731067 6.12691634537884 7.17583364725352e-09 -91.4026639148464 113.625355490834 -0.804421368100533 0.422393742133682 MRPL48 other 2.39701026971811e-05 1 8.79039621788556e-05 6.12691634537884 -0.804421368100533 3.17905104640777e-15 1082.32831646713 129.22001380467 8.37585668504247 3.27143512588991e-14 -543.179616318202 495.406498179447 -1.09643215887219 0.274612457669967 RAB6A other 4.27709527783701e-11 1 4.52079620046727e-10 8.37585668504247 -1.09643215887219 0.114789032616739 28.5062629678014 13.607338493955 2.09491833986971 0.0378478087449865 35.1570682065187 54.2250339673602 0.648354931924633 0.517740140725438 P2RY2 other 1 1 1 2.09491833986971 0.648354931924633 9.09687660329791e-14 99.7694843899349 13.4199522433868 7.43441426470801 6.38758172636202e-12 11.6603284897564 30.2605609733623 0.385330876715098 0.700513846463825 ERCC4 other 1.18841595945484e-09 1 8.55233317342611e-08 7.43441426470801 0.385330876715098 0.794507003483183 -4.90670547741474 13.91892688961 -0.352520385826399 0.72493635829892 9.81211490247734 31.7189392050498 0.309345619632677 0.75748227768566 SUGCT other 1 1 1 -0.352520385826399 0.309345619632677 0.0125059245658241 58.3638787769839 28.2857361076512 2.06336785985911 0.0408247014999727 -116.613620361631 95.5198169797768 -1.22083169805822 0.224091151725568 TMEM70 other 1 1 1 2.06336785985911 -1.22083169805822 1.31312446768302e-07 19.8498289307401 5.52701102398473 3.59142199004141 0.000440190069113312 -17.6232058276567 8.50048195794003 -2.07320078024464 0.0397979484910046 LINC00476 other 0.00129408416290162 1 1 3.59142199004141 -2.07320078024464 0.0455295059158327 139.290450165396 72.2570330835404 1.92770785377189 0.055781049064835 -297.296950956422 236.55194161813 -1.25679353516512 0.210781972808045 RPS6KB2 other 1 1 1 1.92770785377189 -1.25679353516512 1.32537918576356e-07 209.762463665991 39.4924018768067 5.31146381828911 3.69014547951328e-07 48.0093440793917 87.8464423437345 0.546514381214618 0.585493221572539 RMI2 other 0.00130576357381426 1 0.00414329534439751 5.31146381828911 0.546514381214618 0.00271936291272638 176.693777292576 52.9707400331998 3.33568640313184 0.00107738935707445 -52.4024414450195 163.3912122538 -0.320717624419246 0.748879867416978 TOM1L2 other 1 1 1 3.33568640313184 -0.320717624419246 0.0187045473992429 -1.69041311032661 6.33556317574365 -0.266813393448357 0.789981752557323 -24.7610286293015 9.48117331488222 -2.61159962031652 0.0099339756602821 ZNF77 other 1 1 1 -0.266813393448357 -2.61159962031652 2.76878880470295e-10 83.7717509468368 29.2535983587232 2.86363919814523 0.00477625088210202 -220.229017043064 61.6846276917729 -3.5702414893952 0.000476938189235591 KDF1 other 3.21484068114059e-06 1 1 2.86363919814523 -3.5702414893952 0.00998848311426394 56.9569088930881 18.4387976754655 3.08897086976958 0.00246021848281808 12.7324915535697 88.4233122042556 0.143994736638659 0.885729332656408 B3GNTL1 other 1 1 1 3.08897086976958 0.143994736638659 2.4110344909571e-07 402.764842152843 103.889782680582 3.87684747971008 0.000155920923472859 -404.964167206008 230.503279378868 -1.75686943932969 0.0809146714134587 MLXIP other 0.00232182621479169 1 1 3.87684747971008 -1.75686943932969 0.0108752783941731 194.035828877006 70.0651533679442 2.76936279377046 0.00629373262460688 92.2224331550797 102.001364281813 0.904129408507561 0.367312018879486 NR2F1 other 1 1 1 2.76936279377046 0.904129408507561 0.00236768392371796 196.324631763162 123.516678370036 1.58945847924282 0.114423899238635 -507.731588158086 276.026667254202 -1.83942947690086 0.0681691773340133 AURKAIP1 essential 1 1 1 1.58945847924282 -1.83942947690086 2.07315053387431e-05 19.1902192852595 6.5040237369547 2.95051495218631 0.00366184732882072 -17.4864286294475 9.61668729254689 -1.81834223132115 0.0709300288919983 TTLL11 other 0.165706922172574 1 1 2.95051495218631 -1.81834223132115 0.00101786341631604 47.2388733098269 109.057157762154 0.433157018568663 0.665522923956128 -756.276487492017 242.288088599746 -3.12139359331596 0.00215982930175771 TOMM5 other 1 1 1 0.433157018568663 -3.12139359331596 3.04373197534925e-47 120.548975395157 5.71662219395502 21.0874483751314 7.4732029646431e-47 -81.6526654972919 47.7184531958689 -1.71113395403103 0.0891097772754385 SLC35E3 other 4.43867433965181e-43 1 1.08989192036355e-42 21.0874483751314 -1.71113395403103 0.0437547932587215 235.190284331007 100.269650821827 2.3455779730292 0.0202560691669151 13.7519947651783 176.450104223525 0.0779370169583887 0.937978028936451 PRIMA1 other 1 1 1 2.3455779730292 0.0779370169583887 0.00159798412906899 22.1015874618277 8.3758040293671 2.63874218932719 0.00915985199756265 -9.44334351260636 12.9281427442668 -0.730448580233551 0.466204626751585 ZNF169 other 1 1 1 2.63874218932719 -0.730448580233551 2.75543195544765e-08 379.40482854944 63.2209483127409 6.00125177927739 1.42642804060814e-08 -235.495573354616 258.146999205222 -0.912253770447288 0.363108777682106 RUVBL1 essential 0.000285572967862595 1 0.000172426621548712 6.00125177927739 -0.912253770447288 0.0153621032146484 -203.020918081077 89.2757406657933 -2.27408830850357 0.0243510871149378 -533.84847454061 188.248322731025 -2.83587373738989 0.00518866005526178 SFN other 1 1 1 -2.27408830850357 -2.83587373738989 0.00100949018155229 -0.76599858152307 14.06728046272 -0.0544524994403188 0.95664663032134 -73.2099345924505 27.0943177330091 -2.70204015889497 0.00768037096229635 MSRA other 1 1 1 -0.0544524994403188 -2.70204015889497 6.01160421008157e-14 734.198778833103 88.2228642665638 8.32209184021428 5.44875486223224e-14 -124.647444595232 455.185270743165 -0.273838923635916 0.784592810385838 CTDNEP1 other 7.89383748825811e-10 1 7.51056370210092e-10 8.32209184021428 -0.273838923635916 0.0853011509468863 -211.542040200057 220.485904412006 -0.959435664443943 0.338823966140379 -1978.64680779677 939.904109006204 -2.10515816330335 0.0368796902148016 ETV4 other 1 1 1 -0.959435664443943 -2.10515816330335 0.00536698486001981 39.0719984495623 42.5985732292448 0.91721378176907 0.360455570551396 -120.346038308731 58.9033139765747 -2.04311150229326 0.0427351478991032 SWI5 other 1 1 1 0.91721378176907 -2.04311150229326 0.168997881491499 -14.0140914758446 11.772474264588 -1.19041173171212 0.235716382027349 4.27389316603011 16.6596707778247 0.25654127401599 0.797875314163718 GAPT other 1 1 1 -1.19041173171212 0.25654127401599 0.00015627812516919 506.995745327457 121.476022602162 4.17362813226018 5.12796772384041e-05 695.879425619201 541.752228116664 1.28449757934239 0.201002271934579 BAIAP2 other 1 1 0.484644229580157 4.17362813226018 1.28449757934239 0.330598619481167 75.5546117717598 55.4187351161709 1.36334060337861 0.174963623168099 -47.1614369941041 195.07540582256 -0.241760035280932 0.809319865271952 HOXD8 other 1 1 1 1.36334060337861 -0.241760035280932 2.1448630054151e-24 230.027392621388 21.3925329146192 10.7526955101325 1.94114592251123e-20 8.61267158079304 50.6231926058583 0.170132920059972 0.865130364302919 ZDHHC21 other 3.08366954288529e-20 1 2.78263267991985e-16 10.7526955101325 0.170132920059972 0.459104507023011 4.84641220960182 9.70715863478 0.499261667800246 0.618312193330326 -13.1609666838352 17.3547510125944 -0.758349496013184 0.449408352214774 TSPEAR other 1 1 1 0.499261667800246 -0.758349496013184 0.000221245335263584 169.077690088717 45.9664981719863 3.6782808526354 0.000325291150925154 -185.602773635225 192.228858533846 -0.965530228139734 0.335812971922593 PLEKHF2 other 1 1 1 3.6782808526354 -0.965530228139734 0.711804253383088 -196.164027484124 341.756687293109 -0.573987385697834 0.566819189119028 -1104.15992169501 1490.69493269164 -0.740701465793077 0.460009697711847 A2M other 1 1 1 -0.573987385697834 -0.740701465793077 0.0507439738761377 48.8884870910772 57.924227725447 0.844007576981467 0.399965895243672 -549.36372046085 247.48957493485 -2.21974489473129 0.0278877763034133 ARL4D other 1 1 1 0.844007576981467 -2.21974489473129 0.000537616002819311 210.093872396681 123.464412679996 1.70165530160677 0.0909340661484878 -447.728021625675 229.761250193266 -1.9486663710659 0.0532396643551601 DOK7 other 1 1 1 1.70165530160677 -1.9486663710659 0.0632559745713434 99.2547375916366 43.37957994634 2.28805206768746 0.023522366225833 132.538007945884 82.1595431383516 1.61317849251788 0.108793690329663 LRRN1 other 1 1 1 2.28805206768746 1.61317849251788 1.39796690619366e-13 425.917683881064 50.3274263936561 8.46293391896454 1.72587548253973e-14 187.571987480437 221.596953565462 0.846455623429978 0.398586961491879 UBE2O other 1.81721718136114e-09 1 2.39482481957213e-10 8.46293391896454 0.846455623429978 8.67059999116274e-11 271.43793911007 45.0442042797758 6.02603472411526 1.2184391378091e-08 -107.617017954723 93.2288083786401 -1.15433222655433 0.25017563940382 ORAI3 other 1.02937363095084e-06 1 0.000147808851807622 6.02603472411526 -1.15433222655433 0.841286264762175 0.318658524674823 3.69162958873926 0.0863192032176903 0.931326275980097 -6.37338908086334 12.2147737373967 -0.521777088784756 0.602585033875179 DENND2C other 1 1 1 0.0863192032176903 -0.521777088784756 0.054333326748369 22.5275229357798 9.56981879195478 2.35401771188378 0.0198594746807293 9.48651863861646 13.7681176383107 0.689020742546504 0.491867572584773 PLEKHD1 other 1 1 1 2.35401771188378 0.689020742546504 0.000100477367739874 186.567287529295 81.6669550879307 2.28448933021218 0.0238044071324006 -438.866420553667 218.54110343334 -2.00816420187761 0.046496002304159 TUBB6 other 0.736700060268755 1 1 2.28448933021218 -2.00816420187761 2.2800630197814e-08 62.7983788743881 27.331201620519 2.29768086110206 0.0229351417643513 -109.772547191797 40.0409975311946 -2.74150380759812 0.00684487443511406 LYSMD3 other 0.000237582566661222 1 1 2.29768086110206 -2.74150380759812 0.00347418193102963 25.7710221994426 12.5994289625809 2.04541192112595 0.0427566269739193 -45.7415297220532 26.9921908763452 -1.69462086021847 0.0924529591502223 AMIGO3 other 1 1 1 2.04541192112595 -1.69462086021847 3.61632599537815e-12 256.508324289987 43.5898944744414 5.88458236439155 3.53416772163675e-08 -157.094915433684 96.2358335629911 -1.63239522761402 0.10515379151168 B3GALT6 other 4.51281320963239e-08 1 0.000420071175393745 5.88458236439155 -1.63239522761402 9.61838291049687e-10 26.0566407114644 5.63232257712785 4.62626924410848 7.77441910753326e-06 -17.8420077488494 10.9226900691674 -1.63348109631105 0.104384486300807 ZNF613 other 1.08658871739883e-05 1 0.0796722470140008 4.62626924410848 -1.63348109631105 0.00809018988686282 -21.6896015343186 13.0153005190952 -1.66646951428414 0.0976394625777258 -64.011083668315 20.4684256115744 -3.12730861098171 0.00210744426934431 C11orf16 other 1 1 1 -1.66646951428414 -3.12730861098171 0.227733040716879 -405.678843946247 265.803466449197 -1.52623609227378 0.129029201622836 -798.568415603124 555.971783769337 -1.43634702140646 0.152958596403058 NUPR1 other 1 1 1 -1.52623609227378 -1.43634702140646 0.0162195311977448 28.6580156046814 11.3291093808525 2.52959121862807 0.012405344342137 -2.41212743823146 16.9558325338168 -0.142259451632392 0.88705746943189 JAKMIP2 other 1 1 1 2.52959121862807 -0.142259451632392 1.62656378119098e-12 80.5459573817294 19.3149225937563 4.17014135007544 5.08119858026254e-05 -63.5734094616638 28.2969178827171 -2.24665490867797 0.0260932432983085 MBLAC2 other 2.05207286635055e-08 1 0.480528949735429 4.17014135007544 -2.24665490867797 0.301166229981241 -19.1321047052109 75.195546532386 -0.254431353816557 0.799594222153476 -172.68846666123 117.645858393074 -1.46786694423403 0.144735036177386 TPRN other 1 1 1 -0.254431353816557 -1.46786694423403 0.929531799653259 -0.466777958174071 12.8110357813976 -0.0364356142734267 0.970982203411792 -8.93888976542259 27.0787120761861 -0.330107641023435 0.741767257043089 ZNF683 other 1 1 1 -0.0364356142734267 -0.330107641023435 8.86174372166017e-07 719.514899352862 175.506127982836 4.09965684744198 6.86334896140235e-05 -355.90499212566 258.880142162895 -1.37478676097803 0.171318313503761 SLC35A4 other 0.00812090194652938 1 0.638840521327331 4.09965684744198 -1.37478676097803 0.0703873595226164 23.6578804057389 21.8018738765069 1.08513059655996 0.279559592952509 -47.585011612658 46.0826646257986 -1.03260113101225 0.303409501006395 CRYBG2 other 1 1 1 1.08513059655996 -1.03260113101225 7.49149531628041e-10 349.891058565447 70.5509857508821 4.95940708469934 2.07298884520814e-06 -379.898108988893 151.293714429426 -2.51099730363288 0.0132098612442213 IP6K1 other 8.51258612788943e-06 1 0.0222120754764052 4.95940708469934 -2.51099730363288 0.112460108375345 99.7357769985594 88.1761612462226 1.13109683602644 0.260251199244653 -139.726249694202 137.954448873513 -1.01284337573132 0.313156027446664 SSNA1 other 1 1 1 1.13109683602644 -1.01284337573132 0.000320075166249585 99.1195043646685 41.8068498741253 2.37089148460369 0.0189744406025372 -126.724090583459 69.6512105451423 -1.81940973590584 0.0707786587994302 CSTF3 essential 1 1 1 2.37089148460369 -1.81940973590584 5.24377668277435e-19 426.185387093556 48.3005538113198 8.82361284631222 3.84070590235664e-15 -74.2033231422853 127.672950411461 -0.581198467671848 0.562034608850502 YES1 other 7.36593310629313e-15 1 5.36162543968988e-11 8.82361284631222 -0.581198467671848 1.3352115700821e-05 110.024266828749 24.7693271373248 4.44195622346779 1.74948386721238e-05 -212.846223978119 110.464912154256 -1.92682200915432 0.0559442572329632 CHMP6 essential 0.108913207771597 1 0.173433805089393 4.44195622346779 -1.92682200915432 0.00210799733898546 24.2618380127901 12.9373976043267 1.87532599327983 0.0627046488546157 -32.521004915084 22.0072706878326 -1.47773912432786 0.141588296999745 DLEU1 other 1 1 1 1.87532599327983 -1.47773912432786 9.72863656097691e-05 14.8366897661151 4.86426315419927 3.05014126411042 0.00271107256055855 -35.7551380968875 16.3472958076557 -2.18722035238042 0.0302962160356784 UFSP1 other 0.714665641769364 1 1 3.05014126411042 -2.18722035238042 0.0690998213452706 20.9571181833626 11.8562112177478 1.76760668298415 0.0791071281159721 -8.10573928308511 19.2304024216458 -0.421506482566443 0.673973032141957 TCP11L1 other 1 1 1 1.76760668298415 -0.421506482566443 0.0295620668013408 91.7302033287575 35.5091962596923 2.58328019192267 0.010842408428282 -94.2579143788634 160.494384289089 -0.587297273959955 0.557977841462616 CCDC57 other 1 1 1 2.58328019192267 -0.587297273959955 0.0409865784282137 33.1265653658844 16.0880855739452 2.05907441339902 0.0411824214370369 66.0332442603251 29.2061998373049 2.2609324262714 0.0251734252329442 FOXG1 other 1 1 1 2.05907441339902 2.2609324262714 0.020567243903109 57.6922423429464 20.5413876960997 2.80858543719034 0.00560837786788683 34.2980661748257 90.4458912692689 0.379210881705129 0.705043654434354 SPHK1 other 1 1 1 2.80858543719034 0.379210881705129 0.123653359465184 478.712201695072 234.275595677531 2.04337203928827 0.0427894345138109 403.895817205477 444.050023993705 0.909572785455368 0.364526740250893 BNIP3 other 1 1 1 2.04337203928827 0.909572785455368 5.75363169561381e-18 71.5689794105518 12.0990015116618 5.91527981392258 2.02538099104857e-08 -103.062840645919 26.0020405106532 -3.96364433797775 0.000112091875566073 MYPOP other 8.01653504149873e-14 1 0.000243309018454664 5.91527981392258 -3.96364433797775 1.37241183077838e-09 63.6355964048139 9.29734295879566 6.84449274237131 1.90057284459791e-10 48.8829634895649 35.9345517478772 1.36033319220276 0.175792806892871 ATAD5 other 1.53874814466872e-05 1 2.45592022978942e-06 6.84449274237131 1.36033319220276 5.29963687745062e-06 193.115100611536 42.3581320644995 4.55910332206047 1.339472018643e-05 -19.5249625720012 119.472928157204 -0.16342583104944 0.870483045576718 SMIM19 other 0.0449356210839038 1 0.13429774001968 4.55910332206047 -0.16342583104944 1.39396952250117e-10 19.7516420312045 3.76631773643047 5.24428458070671 5.00206336227984e-07 -20.1129847812473 10.5004968760611 -1.91543171895995 0.0572553021727819 ZNF404 other 1.63944755541363e-06 1 0.00557630023626957 5.24428458070671 -1.91543171895995 5.16331868850448e-14 69.1938440326047 13.1585490011539 5.25847067382102 4.91976822480352e-07 -26.4294921186523 22.8324113508158 -1.15754274537928 0.248890569060986 RTTN essential 6.79079673912109e-10 1 0.00548652552430089 5.25847067382102 -1.15754274537928 0.00028441197409196 20.1735352215103 5.45163550830389 3.70045561387626 0.000297295573041833 -17.1634375368529 26.9151517892725 -0.637686819351086 0.524606485657484 ACBD7 other 1 1 1 3.70045561387626 -0.637686819351086 2.00556676695267e-05 262.413071842127 65.5748093202712 4.00173594955474 0.000108775943036027 -50.5608469923084 102.593904655282 -0.492825057806251 0.62302934414939 ANAPC2 essential 0.160425285688544 1 0.990296185399986 4.00173594955474 -0.492825057806251 1.52682241058498e-08 75.8935511456912 19.8847780930213 3.81666573248441 0.0001977937563214 -156.502569310295 55.966034397357 -2.79638482510896 0.00584961335682991 ZBTB8OS other 0.000160972886747975 1 1 3.81666573248441 -2.79638482510896 2.99888726800619e-05 14.2317510805638 9.1612274708426 1.55347644470778 0.12231012836789 -44.3296691097506 16.1644854016207 -2.74241140428176 0.00680328027626484 SLC35G1 other 0.235022795193645 1 1 1.55347644470778 -2.74241140428176 1.09950016337112e-05 259.486311695689 64.8987419999694 3.99832575638849 0.000100647165013946 -26.1666848740412 128.305154063035 -0.203941026883346 0.83868164923254 ZNF135 other 0.090488863445443 1 0.920820912712588 3.99832575638849 -0.203941026883346 0.809959129213672 -166.742544162784 443.092727767769 -0.376315235419923 0.707228849035472 -892.400196196465 1472.64473914875 -0.6059847106861 0.545465870246471 COX8A other 1 1 1 -0.376315235419923 -0.6059847106861 6.51521894545045e-08 84.0132799708933 14.809160055847 5.6730617843328 6.81909942561833e-08 4.37662843926006 25.8771057922181 0.169131295995869 0.865916769719328 ZSCAN2 other 0.00065812301719602 1 0.000799266643676724 5.6730617843328 0.169131295995869 0.617463227494855 -3.59621475997697 4.70541891214 -0.764270902787999 0.445867732599879 0.856549570017561 9.85264040889844 0.086936042976253 0.930834557364661 PRR18 other 1 1 1 -0.764270902787999 0.086936042976253 1.46417336658136e-14 116.680274050814 30.0446718635062 3.88355960687124 0.000152412951537053 -328.837853268627 66.7099268699554 -4.92936911637851 2.11249498376916e-06 B3GNT4 other 1.94661849086991e-10 0.0307917268834193 1 3.88355960687124 -4.92936911637851 2.35749210170583e-07 52.232429644065 15.9957996280577 3.26538409198662 0.00134048531313036 -65.710604688485 25.1118269984149 -2.616719392525 0.00973967292377567 CDC26 essential 0.00227238663683425 1 1 3.26538409198662 -2.616719392525 7.04931911606683e-10 640.731824314196 103.106237868006 6.21428768581826 5.55277866423299e-09 325.153146883098 161.596169147946 2.01213400415087 0.0461242581350653 HSD11B2 other 8.0164856987912e-06 1 6.830473034873e-05 6.21428768581826 2.01213400415087 1.48365204110993e-08 91.8530543848067 14.3914642890843 6.38246758910249 2.11443011183461e-09 34.5229675519221 55.623506685271 0.620654281062501 0.535781719594578 CRLF3 other 0.000156569799898331 1 2.64092320968142e-05 6.38246758910249 0.620654281062501 2.82544254205932e-07 394.491748278871 74.4262111365029 5.30044109803393 4.08658141947435e-07 -275.935620091145 278.751483639736 -0.98989830112535 0.323828626210684 RNPEP other 0.00270168815871712 1 0.00457819716423711 5.30044109803393 -0.98989830112535 3.13216172140431e-17 80.7176489171276 10.3070384039703 7.83131349215063 6.93647328702713e-13 -57.0933571685446 35.9198195732056 -1.58946670242001 0.113979665112252 EID2 other 4.33209287687431e-13 1 9.44331473295874e-09 7.83131349215063 -1.58946670242001 0.0104924699550312 0.095065092340297 3.79052500238359 0.0250796637089895 0.98002497818082 -23.0067060248259 8.5510836838075 -2.6905017978472 0.00794926078436881 DMRTA1 other 1 1 1 0.0250796637089895 -2.6905017978472 6.2910609307298e-13 13.272223255185 1.82195832154185 7.28459213268568 1.50108990461334e-11 0.71624888017446 6.34948775920676 0.112804198911306 0.91033081842351 EID2B other 8.03620123291425e-09 1 1.99464826525021e-07 7.28459213268568 0.112804198911306 0.90681883434335 8.20848445595857 19.4898270984818 0.421167638608657 0.674219896145665 21.9051381692573 82.5372255311716 0.265397074208467 0.791058522996993 RIMS2 other 1 1 1 0.421167638608657 0.265397074208467 0.000508739434510364 83.3123275068995 25.4031380773496 3.27960771040268 0.00129980079980163 -168.013464915949 101.574892457969 -1.65408459561473 0.100258725980291 DNAJC30 other 1 1 1 3.27960771040268 -1.65408459561473 1.37850427842524e-09 147.559642687222 28.9996082409039 5.08833227888538 1.19535249194096e-06 -186.583611809452 75.3576944925789 -2.47597293237024 0.0145339360661134 SPRYD4 other 1.54488974483116e-05 1 0.0130006537023499 5.08833227888538 -2.47597293237024 0.00390667357539082 76.600643974241 22.8123420731451 3.35785969404763 0.00100185512819554 10.9260265952998 91.2155492655525 0.11978250071697 0.904820114001466 VPS37D other 1 1 1 3.35785969404763 0.11978250071697 0.0554322931247963 -17.9915416533673 11.932222000667 -1.50781150839815 0.133734438610359 19.0668049792532 18.0969828892104 1.05359026396721 0.293787585855829 CLEC14A other 1 1 1 -1.50781150839815 1.05359026396721 0.156448684967468 -16.5178704899096 14.8927531691505 -1.10912134931004 0.269095726601001 -47.5803917238566 24.8972713026303 -1.91106853219011 0.0578415856111365 SYNE3 other 1 1 1 -1.10912134931004 -1.91106853219011 4.72732412552659e-12 362.437573705059 78.5737966033575 4.61270282680438 8.41870655416559e-06 -344.740893834477 114.582109606074 -3.00867993284182 0.00307523759923566 LPCAT4 other 5.87464569079189e-08 1 0.0860560183966807 4.61270282680438 -3.00867993284182 0.00242193719175235 399.154950850971 143.347974675176 2.78451754728624 0.00604268372842467 -368.335880906493 282.869932098386 -1.30213868322484 0.194838703459409 SLCO3A1 other 1 1 1 2.78451754728624 -1.30213868322484 5.02906098441312e-08 33.0362552239998 7.94477485170375 4.15823680855036 5.29241425750478e-05 -43.7579835138996 22.5334708850955 -1.94191049115486 0.0539612063472843 ZNF575 other 0.000511204049065593 1 0.499339285195576 4.15823680855036 -1.94191049115486 6.22011875123234e-09 71.4791666666667 16.0813953183991 4.44483611349855 1.68028274539236e-05 -63.0499999999999 25.7876021068799 -2.44497335342315 0.0156213975109268 WDR25 other 6.71461819195531e-05 1 0.166919287927277 4.44483611349855 -2.44497335342315 2.90172703214399e-05 29.7711166378621 23.812176067709 1.25024762765104 0.213130462093814 -170.848745942756 49.9228941628753 -3.42225243162696 0.000798077411427011 SGF29 other 0.228017710185875 1 1 1.25024762765104 -3.42225243162696 0.0138369536924134 -145.190664556963 77.6180307327923 -1.8705790804819 0.0634189995343212 -673.153481012659 246.343937936798 -2.73257579078469 0.00706603162382249 PLA2G16 other 1 1 1 -1.8705790804819 -2.73257579078469 0.026314452839952 -7.20784066599234 13.4203838490061 -0.537081557956046 0.592034472773146 -51.836457936021 19.7625701922506 -2.62296135734143 0.00964862109085902 DIRAS1 other 1 1 1 -0.537081557956046 -2.62296135734143 4.97903960137697e-13 47.2709368042473 8.10341924870399 5.83345565044132 3.00543240748006e-08 -53.0327738768055 23.1091938059831 -2.29487771499303 0.023064572261492 PHLDB3 other 6.38163505708486e-09 1 0.000358277597295698 5.83345565044132 -2.29487771499303 0.0275652549363704 -134.836882230906 72.6241798424507 -1.85663896684848 0.0652981246172742 -422.427165930583 158.152336285956 -2.67101438935932 0.00838594753503103 PRR15 other 1 1 1 -1.85663896684848 -2.67101438935932 0.000197181371696836 32.7857241059308 24.5847762864312 1.33357829755912 0.184447702280722 -107.435975871728 36.3269761377125 -2.95747092916425 0.00362643151033965 GNG7 other 1 1 1 1.33357829755912 -2.95747092916425 6.6407237627863e-12 100.64887063655 13.3166083207699 7.55814605431989 3.41642060304446e-12 -60.5983572895284 52.9324711615376 -1.14482388522154 0.25405824605878 CNTD1 other 8.21125493268526e-08 1 4.59713556345663e-08 7.55814605431989 -1.14482388522154 0.138362573949907 -18.8425418750497 15.0489176904569 -1.25208618072238 0.212752475929971 -55.6604350242121 27.9152721483965 -1.99390622911801 0.0482230703681287 KBTBD11 other 1 1 1 -1.25208618072238 -1.99390622911801 0.903515110476656 4.99018152802674 18.307974193215 0.272568743836013 0.785559601518912 30.6535647316975 82.489828998254 0.371604173556309 0.710711969185712 B3GNT5 other 1 1 1 0.272568743836013 0.371604173556309 0.0759989457729564 -23.1066173252811 13.1718641163027 -1.75424048724298 0.0813913993161063 -65.1346494682944 32.534140029276 -2.00203999274862 0.0470477150950739 MAP3K19 other 1 1 1 -1.75424048724298 -2.00203999274862 1.00507396082245e-13 163.910257471645 23.6433214035546 6.93262400294583 1.08495772285899e-10 -133.985332671027 77.8831610365142 -1.72033762995585 0.0873928853894218 RMDN1 other 1.31121948928897e-09 1 1.41249850423289e-06 6.93262400294583 -1.72033762995585 1.93594587136169e-17 286.584875267586 50.1535392469662 5.71415057781634 5.59076169257301e-08 -173.686081261525 100.370955890957 -1.73044163742166 0.0855676827742905 MEX3C other 2.68399535605584e-13 1 0.000658088558832769 5.71415057781634 -1.73044163742166 0.0110106435869564 195.329121984702 82.5505768597593 2.36617513062974 0.0192172311613487 66.2121037343639 154.22465812566 0.429322421842656 0.668288632619568 RNF152 other 1 1 1 2.36617513062974 0.429322421842656 3.58179851813355e-08 512.22691015953 94.7015729959919 5.40885324239766 2.43285979413438e-07 -794.892917116469 365.563707439634 -2.17443061479983 0.0312298505264972 MYO1D other 0.000368101433708585 1 0.00276324215417783 5.40885324239766 -2.17443061479983 0.050357708355322 25.8458752997602 10.6597907131472 2.42461376543569 0.0164747258670537 28.4284892086329 44.9466870800293 0.632493539691031 0.527996354671097 LRRC37A other 1 1 1 2.42461376543569 0.632493539691031 0.144739610365975 -7.5033196418976 9.06610694424356 -0.827623111887266 0.409164631945824 -30.2011457090555 15.3699123948398 -1.96495236493313 0.0512190771767558 BDNF other 1 1 1 -0.827623111887266 -1.96495236493313 4.51766761783021e-05 24.3303723056826 5.52538739473562 4.40337854479916 2.04777728413236e-05 -10.1442194644023 21.4261364968744 -0.473450706611627 0.636598811000874 CCDC121 other 0.345601572764011 1 0.201849406896927 4.40337854479916 -0.473450706611627 4.4186932207766e-07 124.82 30.0047818372378 4.16000358466499 5.46521835855395e-05 -30.0619166666667 52.0004741855505 -0.578108510307009 0.564100137097402 ACSF3 other 0.00415931592871701 1 0.514550308457855 4.16000358466499 -0.578108510307009 0.767049106081433 27.7561057667635 75.1390342895179 0.369396626257088 0.712386281215134 -61.2429419446075 157.561317029393 -0.388692752125082 0.698089755555692 BOK other 1 1 1 0.369396626257088 -0.388692752125082 0.000285190433448213 22.4789177446431 5.7272593330793 3.92489957889809 0.00013215870025324 5.99748527039929 11.8419124851661 0.50646255644197 0.613280568742581 ZNF843 other 1 1 1 3.92489957889809 0.50646255644197 0.000332227146904191 226.019434169581 101.151731304319 2.23445937360768 0.0269312313109503 -711.049193528094 332.975534240776 -2.1354397558048 0.0343489496942739 C8orf59 other 1 1 1 2.23445937360768 -2.1354397558048 0.0956438616960003 1.81215074996849 1.34804185639252 1.34428374117253 0.180846429667692 -6.14898767091951 4.57183240939944 -1.34497223876307 0.18062446902794 PFN4 other 1 1 1 1.34428374117253 -1.34497223876307 0.00016699476884097 25.6868870832166 6.06462755107247 4.23552590276944 3.94840228912977e-05 31.327022375215 23.3913708279347 1.33925551459359 0.182499916000398 CDK5R1 other 1 1 0.377111902634784 4.23552590276944 1.33925551459359 0.275247872457056 -0.403501561729411 2.30589529472094 -0.174986940063227 0.861325873355604 -6.82711381445559 4.48679534524012 -1.52160134107704 0.130214276122347 TCERG1L other 1 1 1 -0.174986940063227 -1.52160134107704 0.0253099281452253 16.9164183148198 6.33055471513175 2.67218578403326 0.00835256881892009 5.81922243294502 15.8981621528276 0.366031141021545 0.714847454197343 NCKAP5 other 1 1 1 2.67218578403326 0.366031141021545 2.17076904728216e-07 229.172731804587 55.5734532774703 4.12378065945191 6.07645863936162e-05 -158.712884075048 90.8280848247846 -1.74739877408203 0.0825615023858561 RUFY1 other 0.00209956782253131 1 0.569242645335396 4.12378065945191 -1.74739877408203 0.0443020478553008 152.810235551317 67.474805232933 2.26470065417445 0.0249637599227593 -169.504269678471 280.622339620818 -0.604029849895446 0.546736244116302 BASP1 other 1 1 1 2.26470065417445 -0.604029849895446 0.279995190700754 41.5849820664121 29.2711095832626 1.42068348820609 0.157443543525537 89.8509776697905 114.875688195701 0.78215834073369 0.435330322428537 LRRC37A3 other 1 1 1 1.42068348820609 0.78215834073369 0.00013114442261623 54.2366327595201 19.1667473352971 2.82972545162313 0.00529280673889934 -81.5847026604068 49.1004118731121 -1.66158896734395 0.0986699705106168 FKBP9P1 other 0.946731586866563 1 1 2.82972545162313 -1.66158896734395 0.0108501440503613 53.0712555723263 39.423639568475 1.34617848968882 0.180210436099685 -129.307985538278 76.3386082577891 -1.69387402376548 0.0922977496889149 VSIG10 other 1 1 1 1.34617848968882 -1.69387402376548 0.384760529109759 92.0803149660284 68.0582783802331 1.35296274248354 0.178063385209476 76.8648882124274 105.496078858069 0.728604219649143 0.467357538695154 IRX5 other 1 1 1 1.35296274248354 0.728604219649143 0.140072001057824 108.616497722932 54.5780656879096 1.99011262773634 0.0487261586139298 84.7930071984721 260.478642991773 0.325527675607364 0.745317447569917 METRNL other 1 1 1 1.99011262773634 0.325527675607364 1.10324704917716e-09 264.66676989334 38.9788329578185 6.79001267636086 2.53596796998998e-10 46.5791117224694 288.802519597167 0.161283605792082 0.872089990951718 FAM91A1 other 1.24258715148823e-05 1 3.26150840620411e-06 6.79001267636086 0.161283605792082 1.14041634380607e-06 134.740154094563 68.3133436581466 1.97238411823068 0.0503449932588447 -452.956655200252 132.279658534345 -3.42423514105645 0.000789023961223996 WSB2 other 0.010356120818103 1 1 1.97238411823068 -3.42423514105645 0.905895568444466 0.119125282013642 5.4751127485188 0.0217575943154539 0.982677159905384 -3.24200168528637 8.56599052473059 -0.378473648310314 0.705741983268425 GRIN1 other 1 1 1 0.0217575943154539 -0.378473648310314 2.36186787036357e-06 449.772417563929 89.639945646243 5.017544514573 1.4275306816612e-06 60.840707716465 266.15912248747 0.228587722817313 0.819492628697788 SOX11 other 0.0208033322021623 1 0.0154473095062558 5.017544514573 0.228587722817313 4.71167291732388e-05 220.091349736813 69.4564709158329 3.16876666543451 0.00187757473722873 -222.424431228031 183.594428371005 -1.21149880855076 0.227730751338956 TYMS other 0.359736227237678 1 1 3.16876666543451 -1.21149880855076 0.0223091544196017 36.2263079293493 37.6629404693074 0.961855539635073 0.337691032636217 -121.514846445672 72.2590165091855 -1.68165652282611 0.0947443843280819 PXMP2 other 1 1 1 0.961855539635073 -1.68165652282611 3.6417446217022e-10 587.316430283949 124.217187203344 4.72814143925598 5.10285606714299e-06 -367.583462838326 185.669062541179 -1.97977766358787 0.0495224160564446 PNMA1 other 4.20512251467953e-06 1 0.0531513487953613 4.72814143925598 -1.97977766358787 0.417691767398536 29.5086993035471 44.4242389182396 0.664247717509718 0.507506149011165 -39.5672234334039 77.4822869463173 -0.510661533013572 0.610305362949979 MAMSTR other 1 1 1 0.664247717509718 -0.510661533013572 4.07076097510424e-08 475.982288001942 99.1154395680259 4.80230214461452 3.82497640665603e-06 -119.907388086862 188.970285392633 -0.634530385757337 0.52672103012509 ANKLE2 essential 0.000416764508631172 1 0.0402272768688015 4.80230214461452 -0.634530385757337 0.0667577981914248 -113.499291670555 50.6317098732149 -2.24166420519403 0.0263846932397815 -168.654303419492 88.3090125685506 -1.90981983054756 0.0579799318047486 FUT2 other 1 1 1 -2.24166420519403 -1.90981983054756 0.176336289675026 -4.36938079758976 6.56874785496522 -0.665177122651619 0.506938663160134 -15.9363751684769 9.34068986339673 -1.70612400171069 0.0900140284237421 GCNT4 other 1 1 1 -0.665177122651619 -1.70612400171069 0.0681351770763657 352.135858088133 153.196445279694 2.2985902671908 0.0228820384264373 83.831300967089 662.459274385368 0.126545591870335 0.899466210393371 MUC20 other 1 1 1 2.2985902671908 0.126545591870335 1.06315224158101e-06 222.46793866577 76.1567116770248 2.92118624566198 0.00406199010867714 -448.837552105014 159.695315569603 -2.81058683846858 0.00564907760060459 THAP4 other 0.00968212746407823 1 1 2.92118624566198 -2.81058683846858 0.948964345892473 -2.32304810725552 8.47657973018293 -0.274054887843942 0.78451363023862 3.00949658254466 36.4961180794497 0.0824607311931967 0.934417733297155 LY6H other 1 1 1 -0.274054887843942 0.0824607311931967 0.588580935964984 -41.2424557122227 41.3363271209691 -0.997729082013705 0.319975869518677 -21.1946391427959 70.3375512187145 -0.30132750963836 0.763571251070139 FIBIN other 1 1 1 -0.997729082013705 -0.30132750963836 0.000518741544599333 431.284230595903 113.026436207893 3.81578190966428 0.000199900431344367 -26.7016604846252 359.159116312311 -0.0743449331282086 0.940837688812105 FAM89B other 1 1 1 3.81578190966428 -0.0743449331282086 0.210432660332108 -70.800307157031 251.698024248397 -0.281290675079592 0.778967923695688 -658.49455000136 393.789678831446 -1.6721986009268 0.0970691186926598 DPP7 other 1 1 1 -0.281290675079592 -1.6721986009268 2.36175217481435e-08 689.000352327711 124.119425837811 5.55110811766112 1.32567835294342e-07 -153.720212649346 280.643494608286 -0.54774194165414 0.584717125491873 SEC24C other 0.000245834783876425 1 0.001529965387132 5.55110811766112 -0.54774194165414 1.03146474619124e-10 350.970651435543 47.8949931671039 7.32791943848951 1.28484770546425e-11 246.193794795725 139.901864710448 1.75976063868246 0.0804601122898053 SMCR8 other 1.22073852711733e-06 1 1.70974684166128e-07 7.32791943848951 1.75976063868246 2.1181778625162e-08 239.618225609492 56.0118668849225 4.27799034268564 3.2877936521361e-05 -191.135895759488 128.319350576478 -1.48953291067018 0.138379065722828 MTHFR other 0.000221349586632943 1 0.31694330806592 4.27799034268564 -1.48953291067018 3.20204873323908e-05 138.272093787451 61.3145356188474 2.25512747331235 0.0255823225273396 -240.229230293424 105.92683291165 -2.26787890933915 0.0247741363694551 DEAF1 other 0.250080006065972 1 1 2.25512747331235 -2.26787890933915 3.40520528583265e-15 198.052732196281 32.827708327188 6.0330964995279 1.12510308573683e-08 -33.0767529769766 46.2178683971037 -0.715670240193278 0.475264821851193 MTX3 other 4.57897954785917e-11 1 0.00013667752285531 6.0330964995279 -0.715670240193278 3.56136106249514e-05 104.492674063479 33.7905610294389 3.09236280428853 0.00237110523691634 -75.725828275409 58.3764857065322 -1.29719744789186 0.196568232685922 TMEM80 other 0.276361618449623 1 1 3.09236280428853 -1.29719744789186 2.05046824076871e-16 283.929693473611 39.2396700412264 7.23578188030902 1.92728414764293e-11 -367.408418587095 125.67810047477 -2.92340843153381 0.00397439870996857 SIX5 other 2.80914148985314e-12 1 2.55557877977452e-07 7.23578188030902 -2.92340843153381 5.31946260189526e-33 324.861717109148 24.8231200861755 13.0870622218868 6.2510535107833e-27 -229.336168565317 79.5043020751692 -2.8845755837022 0.00447044489483746 FBXO46 other 7.72651942925287e-29 1 9.05152548361422e-23 13.0870622218868 -2.8845755837022 2.06057326164366e-07 158.64138491113 51.1566946972601 3.1010874695864 0.00228871386315884 -196.139431725896 82.7882651429716 -2.36916948781536 0.0190518476550753 ZDHHC13 other 0.00199875606379435 1 1 3.1010874695864 -2.36916948781536 1.02673397595404e-07 57.6132850714146 21.1442048300969 2.72477898953227 0.00718412679378597 -80.7054392486793 33.9252825805571 -2.37891722956295 0.0185970028129914 SLC38A9 other 0.00102077891889351 1 1 2.72477898953227 -2.37891722956295 0.00335581782387388 26.7595566360097 8.84180087550282 3.02648261511408 0.00289509680337466 3.19860598745389 20.1939257386619 0.158394461228015 0.874350835524575 ACER2 other 1 1 1 3.02648261511408 0.158394461228015 1.01112989480059e-11 299.030853695392 50.7745709508255 5.88938218670521 2.37410807512909e-08 -213.68319696444 89.0437714241386 -2.39975456505106 0.0176083500578579 WDR73 essential 1.24298197967836e-07 1 0.000284275700915957 5.88938218670521 -2.39975456505106 0.000115019541583907 326.016527371992 87.1043060257484 3.74282905457762 0.000259797329585738 14.1116145910856 168.445197602119 0.0837757014861199 0.933347975730492 POLE other 0.838262419063517 1 1 3.74282905457762 0.0837757014861199 0.00178799394161743 57.8776223276553 31.3118305498396 1.84842665891189 0.0664460066832447 -65.6209629015665 46.5596962517821 -1.40939413665214 0.160721835887493 FAM109B other 1 1 1 1.84842665891189 -1.40939413665214 0.387020588480882 -4.03943060410615 8.26981878420625 -0.488454548946184 0.625922724052616 -31.8430037910492 23.0436759431582 -1.38185434778706 0.169017671016831 SCN4B other 1 1 1 -0.488454548946184 -1.38185434778706 0.00443511956446452 64.7599115087929 24.4964752444651 2.64364202859859 0.00906194234460038 -64.0165644291079 68.1639950985404 -0.93915511167682 0.34914110832921 DSCAML1 other 1 1 1 2.64364202859859 -0.93915511167682 0.00123026030112449 43.1678383128299 92.8286454308334 0.465027127267458 0.642568896361204 -367.546807264206 143.74130059506 -2.55700209851057 0.0115245243727534 RHOG other 1 1 1 0.465027127267458 -2.55700209851057 0.140308704986206 175.166022345072 207.350163882206 0.844783621413401 0.399586076296926 -381.96269377972 358.21760602232 -1.06628676915428 0.2880187456351 EPS8L2 other 1 1 1 0.844783621413401 -1.06628676915428 1.07011311335545e-07 309.174466512105 56.1961166736025 5.50170518557087 1.70327689444534e-07 -76.2149993898899 184.658084996216 -0.412735783496572 0.680422713737322 ANO6 other 0.00106251531025063 1 0.00195399925330769 5.50170518557087 -0.412735783496572 3.74238328620062e-07 130.375334088002 25.2495479958265 5.16347199995627 7.29455384559197e-07 30.0719454286177 35.7311065038881 0.841618084940789 0.401290066212562 ZBTB34 other 0.00354216578038888 1 0.00803349215015044 5.16347199995627 0.841618084940789 0.855162176556393 -3.07896399241946 5.54751113530965 -0.555017181096222 0.579781418666774 -2.98709363914672 12.3778655436662 -0.241325423079526 0.809661109393218 LINC00982 other 1 1 1 -0.555017181096222 -0.241325423079526 1.47521668819902e-12 58.5050830782687 13.8561428755319 4.22232100259162 4.31191820779402e-05 -136.690260166157 37.1408577660341 -3.68032049844477 0.000330760078337804 FAM210A other 1.86408380720828e-08 1 0.410451494199913 4.22232100259162 -3.68032049844477 0.00750348863962824 140.888250473576 219.081144162285 0.643087067179148 0.521156049769942 -861.342202420073 378.484017167344 -2.27576902418904 0.0242853247658405 TALDO1 other 1 1 1 0.643087067179148 -2.27576902418904 3.03449197190311e-08 545.969233889269 112.723268696214 4.84344749938579 3.18298561265671e-06 -155.806337096446 217.895892448857 -0.715049445610894 0.475704935724988 ULK1 other 0.000313584400376467 1 0.0336473409113941 4.84344749938579 -0.715049445610894 2.48609627902552e-05 73.981371733261 16.1771414945648 4.57320421893555 9.89586468366543e-06 5.83417955815183 72.3395248199567 0.080649956889713 0.935826427586314 RIMKLA other 0.197122573963933 1 0.100561776915408 4.57320421893555 0.080649956889713 0.0361704480266185 25.7046451408339 19.5094992276243 1.31754510153893 0.189808069385988 -133.205627591243 77.1630924673054 -1.72628679504626 0.0865018376818565 CLVS1 other 1 1 1 1.31754510153893 -1.72628679504626 5.90134516929869e-06 23.283409436834 5.90071568219401 3.94586194130553 0.000119631637518556 -11.5810211706102 15.7025111715345 -0.737526695195369 0.461902960830826 B3GNT8 other 0.0497955505385424 1 1 3.94586194130553 -0.737526695195369 3.30504458703063e-12 124.670928739051 27.3117198928548 4.56474104260517 1.04375064730275e-05 -161.0058812736 52.7939940812478 -3.04970071076302 0.00271481364809513 PUS1 other 4.12833119365996e-08 1 0.105773690597661 4.56474104260517 -3.04970071076302 5.97816470662265e-10 310.622870763328 61.9210683191907 5.01643268107276 1.46071236384102e-06 0.481861519679153 95.0090167272401 0.00507174514880542 0.995960044471886 CHD9 other 6.82706409496307e-06 1 0.0157990649273045 5.01643268107276 0.00507174514880542 0.00200360676674545 136.585857463177 68.632192888837 1.99011355624909 0.0484080483901237 -172.23364711795 118.568798656306 -1.45260514629318 0.148436069733935 GATD1 other 1 1 1 1.99011355624909 -1.45260514629318 0.00277685404479384 483.657234499444 166.144016309226 2.91107224469201 0.00428912713367623 -83.4255619886366 259.937673398695 -0.32094448218238 0.748806124983231 MAN1B1 other 1 1 1 2.91107224469201 -0.32094448218238 0.585349256498283 -4.44190257741274 33.9372202917874 -0.130885869238019 0.896033155947337 -46.8988803042189 53.8718854824642 -0.870563186794065 0.385321853198563 CLDN22 other 1 1 1 -0.130885869238019 -0.870563186794065 3.03506293835848e-06 138.309951164838 26.3597305375705 5.24701688310907 5.18508273940397e-07 126.3450644464 81.7425332015736 1.54564655018505 0.12429712855922 TOP3A essential 0.0263959423749037 1 0.00577255261377844 5.24701688310907 1.54564655018505 2.49302998777966e-12 619.926954192057 77.6826700970139 7.98024776205378 3.03603764989487e-13 80.8517808363102 360.544296307835 0.22424923002326 0.822858704646088 CASKIN2 other 3.12800472566714e-08 1 4.15178148623123e-09 7.98024776205378 0.22424923002326 5.83236413317333e-08 319.986949939293 54.7615051253114 5.84328259800499 2.91968868839362e-08 -156.002761408393 214.147937095193 -0.728481271052574 0.467418203392873 ZBTB38 other 0.000590701839407795 1 0.000348172876090939 5.84328259800499 -0.728481271052574 0.0838137932852675 23.0219717776304 11.0311154817097 2.08700306109589 0.0389698433992153 -7.88012595889765 48.070451699401 -0.163928685508812 0.870058552626805 C8orf31 other 1 1 1 2.08700306109589 -0.163928685508812 3.87612489598665e-08 105.540619161365 27.9472960752458 3.77641611114026 0.000243280007027207 -176.081392048814 60.5105317357759 -2.90992967666666 0.00426990209968956 CCDC71 other 0.000397535369332391 1 1 3.77641611114026 -2.90992967666666 6.208626243832e-09 129.886366840547 27.6942262461225 4.69001609527661 6.53115832558884e-06 -392.520331916779 113.926196675166 -3.44539134432757 0.00075726613908058 TIMM22 essential 6.70283289284103e-05 1 0.0673884916034256 4.69001609527661 -3.44539134432757 0.000418660825072241 140.875780777756 41.3295386034209 3.40859795531555 0.000841426787256113 -259.829095305257 188.606240468264 -1.37762724425324 0.170398029797012 HIC1 other 1 1 1 3.40859795531555 -1.37762724425324 0.00268026130699585 35.3957840608493 23.4893652532722 1.50688550666215 0.133849475710536 -67.5702910613191 41.2947650301937 -1.63629193705094 0.103781583077939 PPFIA3 other 1 1 1 1.50688550666215 -1.63629193705094 2.14560781740307e-09 372.41752741987 55.7628828079101 6.67859172028031 4.41020298075772e-10 -116.772967860342 239.283817925628 -0.488010300373244 0.626255122876565 MAGEF1 other 2.37969363028174e-05 1 5.62565492225455e-06 6.67859172028031 -0.488010300373244 0.205341742168771 7.18961972890618 9.3083133300518 0.772386948524236 0.441069033279012 -20.9839945449102 18.146318578004 -1.15637750184469 0.24931750350745 UMODL1 other 1 1 1 0.772386948524236 -1.15637750184469 0.297909322152199 108.354441174817 69.382511355592 1.56169673103197 0.120495225976678 89.5523307030534 213.970790985702 0.418525959971039 0.67616931316626 SAMD9L other 1 1 1 1.56169673103197 0.418525959971039 0.000769919907893529 567.440331672979 168.235728713857 3.37288836331614 0.000942269140498077 -674.733421322119 806.941857126783 -0.836161137711447 0.404368240177573 ZFAS1 other 1 1 1 3.37288836331614 -0.836161137711447 4.17019057290536e-12 401.838526984343 71.8547596635813 5.5923717352298 1.0410398394824e-07 -270.023520021736 156.056944145239 -1.73028839889644 0.0856492568138999 PAWR other 5.19188726326718e-08 1 0.00120843904567117 5.5923717352298 -1.73028839889644 5.23192808447248e-13 352.253277138434 65.7798918196481 5.35502974228391 3.17536197957016e-07 -477.037176106896 172.919526160343 -2.75872359067508 0.00653035577068709 TGIF1 other 6.70000710497545e-09 1 0.00357926802337149 5.35502974228391 -2.75872359067508 4.40813462760409e-12 120.865448831271 16.9616252849963 7.12581765016259 4.21292717142653e-11 -93.9274209389115 52.4101020923219 -1.79216252571796 0.0751498243361317 MIEF2 other 5.48504191712776e-08 1 5.5480037920516e-07 7.12581765016259 -1.79216252571796 0.00386100233731419 -6.18888888888889 8.96345960519363 -0.690457609169445 0.490932462353601 -39.5574074074074 13.4079331361749 -2.95029867807743 0.00366427431730427 NAP1L5 other 1 1 1 -0.690457609169445 -2.95029867807743 0.317028348464868 5.57006240776925 5.79520131140469 0.961150805375411 0.338002827623367 -7.20155978202619 12.2557604739515 -0.587606113658344 0.557668623923775 CD19 other 1 1 1 0.961150805375411 -0.587606113658344 0.0869072280907397 13.8671202721633 8.15716240782281 1.69999315679489 0.0911910818906452 -31.3809619104796 36.1179210164753 -0.868847403929065 0.386309478737518 ERICH5 other 1 1 1 1.69999315679489 -0.868847403929065 1.73261332372096e-09 429.618076079702 81.4417673293929 5.27515659553535 4.33693522772415e-07 -176.052165125369 155.609778537382 -1.13136955003812 0.259624757970798 NR2C2 other 1.93151733328413e-05 1 0.00485216313277778 5.27515659553535 -1.13136955003812 0.674909944835162 -3.01725481276439 3.51143290063997 -0.859265974358924 0.391503866210165 -6.11323764264084 11.2465323085894 -0.543566450075631 0.587510846284911 GPR4 other 1 1 1 -0.859265974358924 -0.543566450075631 0.0009244110418813 20.7729859325803 13.7857195457131 1.50684814555364 0.133911515054981 -45.026205263006 20.60569621753 -2.18513389635924 0.0304001911004399 ACOT4 other 1 1 1 1.50684814555364 -2.18513389635924 0.641595055578999 171.203292372729 207.13535577836 0.826528584313346 0.409766686548865 -296.899097194858 825.420728698468 -0.359694258784865 0.719562244565716 CAVIN1 other 1 1 1 0.826528584313346 -0.359694258784865 1.24511752850092e-09 290.182636896294 64.5482349629095 4.49559367600118 1.54432928675507e-05 -404.12353820558 138.07364036806 -2.92686958298714 0.00405813618727006 ARIH2 other 1.39864051976509e-05 1 0.153907856718011 4.49559367600118 -2.92686958298714 0.699387773254961 122.527008530464 169.246249499138 0.723957008755389 0.47019761942712 48.2619557853687 259.59481542728 0.18591263352441 0.852759528463075 IRX3 other 1 1 1 0.723957008755389 0.18591263352441 0.827399949452648 17.7069616928992 37.8760933623819 0.467497044203762 0.640809463909824 5.03076201932587 69.2797182917229 0.0726152204912605 0.942207155509198 ST8SIA3 other 1 1 1 0.467497044203762 0.0726152204912605 0.486700851746349 9.67130270959162 10.3743498936527 0.932232169604069 0.35264793289402 32.0620878816425 32.0277133764797 1.00107327378507 0.318331791840424 RPRM other 1 1 1 0.932232169604069 1.00107327378507 0.00243390785302626 173.865141879615 65.1686313397948 2.66792685844616 0.00847689426816418 -58.679214829706 112.585158695868 -0.521198491074823 0.603002278518461 SLC25A22 other 1 1 1 2.66792685844616 -0.521198491074823 1.01776150163206e-05 62.6701044526337 21.4942453919436 2.91566897603782 0.00408674676474646 -99.5407876404585 45.4562851118876 -2.18981351853645 0.0300621907396074 RABEP2 other 0.0840874552648411 1 1 2.91566897603782 -2.18981351853645 0.267313283375797 136.442671339292 89.2634124890043 1.52853971783903 0.128429983433205 20.1264372751008 134.010803969403 0.150185184171389 0.880815038105217 ATOX1 other 1 1 1 1.52853971783903 0.150185184171389 5.96050879230903e-08 1145.06866434338 192.550235349804 5.94685673722054 1.95453113994649e-08 1385.48757680308 973.778538993323 1.42279534958264 0.156943339259612 TBL1XR1 other 0.000603297160798419 1 0.000234993278955767 5.94685673722054 1.42279534958264 0.000355967683793321 96.7589625568408 29.3690155726541 3.29459332123254 0.00122986852538494 -219.806079072395 159.602835252741 -1.37720660616284 0.170500062578819 SAMD12 other 1 1 1 3.29459332123254 -1.37720660616284 0.57228196838601 -1.33543855075725 49.932983534102 -0.0267446176102256 0.978699212512264 -230.917835299322 225.774433063253 -1.02278115447478 0.308069026811894 CD163 other 1 1 1 -0.0267446176102256 -1.02278115447478 4.75380094438962e-10 405.166864300875 84.3973724229302 4.80070472183081 3.78947297868522e-06 -71.3458548974614 169.900091500991 -0.419928290015343 0.675138714572715 C18orf32 other 5.45593734387596e-06 1 0.0398690452087472 4.80070472183081 -0.419928290015343 0.222889241439831 66.5261191866084 41.9950612513387 1.58414149674535 0.115281703346007 17.8001990953724 72.5505590377119 0.245348889539498 0.806523904712893 PIDD1 other 1 1 1 1.58414149674535 0.245348889539498 0.000509202648917383 2.66285757721641 1.0477246176463 2.54156247965089 0.0120509963217918 -6.74014577579582 4.08342971644853 -1.65060898407183 0.100910714085132 ZNF491 other 1 1 1 2.54156247965089 -1.65060898407183 0.100106159761778 211.942827734176 2272.84879991718 0.0932498579500315 0.925830335157472 -6945.02722580896 3926.56769936078 -1.76872723395029 0.0789855555388807 RPLP2 essential 1 1 1 0.0932498579500315 -1.76872723395029 0.227436639318306 350.935344827587 601.564837287156 0.583370774146609 0.560480809882861 -2650.07672413793 1888.31320603752 -1.40340951684541 0.162469485349446 JUN og 1 1 1 0.583370774146609 -1.40340951684541 0.0061399354836224 84.1559219543663 41.0872460700868 2.04822493604981 0.0422362146366522 -133.58373780537 87.0316919184084 -1.53488614159775 0.126863719977537 CSTF2T other 1 1 1 2.04822493604981 -1.53488614159775 0.628273873835272 26.4250998668443 27.7070821374297 0.953730881359983 0.341676711634474 40.7457592774851 87.5456850926771 0.465422815920065 0.642269571440046 PGBD5 other 1 1 1 0.953730881359983 0.465422815920065 0.134537400178719 18.9017323423682 10.9537026344974 1.72560210671041 0.0863991605963156 -0.99660365770577 19.6384319657067 -0.0507476187226187 0.959591551089381 CASC2 other 1 1 1 1.72560210671041 -0.0507476187226187 8.51480176579704e-05 154.478886362685 34.5911302490877 4.46585252491885 1.54695035235177e-05 83.1173531586066 141.142708674954 0.588888749117198 0.55681004533916 ACAD9 other 0.630180478686639 1 0.154122663604807 4.46585252491885 0.588888749117198 0.00306913001522584 143.967790536689 65.6742910004736 2.19214837866542 0.029997680609998 -104.582099519505 98.4122990902566 -1.06269338778062 0.289724940784881 IL17RA other 1 1 1 2.19214837866542 -1.06269338778062 2.898070843539e-05 988.069925000966 279.360623522419 3.53689762194302 0.000540003205612945 -359.67365755596 482.622689567555 -0.745248131367877 0.457295685224799 PNPLA2 other 0.227788368302165 1 1 3.53689762194302 -0.745248131367877 9.23695215704757e-05 186.5683936522 76.95118347602 2.42450323990585 0.0164795534905085 -310.669434058096 176.289890676582 -1.76226460216056 0.0799957622219408 AGTRAP other 0.680486265409694 1 1 2.42450323990585 -1.76226460216056 0.452895799596832 -0.725332615866154 3.07137729518965 -0.236158747739055 0.813642747799846 -17.4134459373421 13.862869690853 -1.25612130285202 0.211092099892109 CD163L1 other 1 1 1 -0.236158747739055 -1.25612130285202 0.336547579746278 -7.89399005414213 7.59808028302947 -1.03894533356979 0.300490922489533 -35.756162415067 27.8085626198956 -1.2857968570258 0.200482268678413 SRRM3 other 1 1 1 -1.03894533356979 -1.2857968570258 0.000371058653720489 61.6951184104219 19.9698786902782 3.0894087724457 0.00238274154610822 -98.2085079613547 64.0318169708255 -1.53374545042351 0.127157519125409 THAP5 other 1 1 1 3.0894087724457 -1.53374545042351 0.164951131631073 205.7039132872 126.77902697627 1.62253898135456 0.106801978852926 5.80592067112503 219.023118607605 0.0265082549642933 0.978887419283301 CRACR2B other 1 1 1 1.62253898135456 0.0265082549642933 2.95709629361695e-10 18.6143011408987 2.69330719461122 6.91131749773745 1.38353460665065e-10 6.21479881684586 5.76837784914664 1.07739107585771 0.283082529932683 DNAJC28 other 3.42904886207821e-06 1 1.79513615212922e-06 6.91131749773745 1.07739107585771 0.0161670051564969 60.0719663391308 22.5566376085797 2.66316138874713 0.00860408461646406 137.145709779049 115.646778962097 1.18590168277837 0.237574454342798 NAALADL2 other 1 1 1 2.66316138874713 1.18590168277837 0.0091111420988524 833.377831793405 469.602116119439 1.77464667041969 0.077998257555422 -971.888960838134 811.283399394298 -1.19796480682798 0.232832849014002 CD151 other 1 1 1 1.77464667041969 -1.19796480682798 0.194457760176227 -52.6667330463357 284.793066119915 -0.184929829099701 0.853532225568652 -811.880941726111 497.438801138302 -1.63212226281557 0.104737443531805 POLR2L essential 1 1 1 -0.184929829099701 -1.63212226281557 0.0295264101323567 206.485760888227 194.434129239666 1.0619831080875 0.290021158118091 -405.463360613518 365.009126144474 -1.11083074797706 0.268492567400121 FAM20C other 1 1 1 1.0619831080875 -1.11083074797706 0.940216196073658 -1.63446946408952 4.99505179620045 -0.327217720811783 0.743978407961738 -3.80133114912757 22.3931075769944 -0.169754516475993 0.865441447391678 ANXA2R other 1 1 1 -0.327217720811783 -0.169754516475993 6.96926147207215e-05 642.062954876272 145.134994563361 4.42390173925951 1.8756432821237e-05 29.2017334921213 447.677013522812 0.0652294681434058 0.948079923225533 FLII other 0.521718913799321 1 0.185426094870749 4.42390173925951 0.0652294681434058 5.09350243307861e-10 942.148025454154 146.92049650309 6.41263845330348 1.75985256444925e-09 -171.802029244541 529.77533842322 -0.324292236320171 0.746168570007053 SOX12 other 5.83613508782148e-06 1 2.20403935171624e-05 6.41263845330348 -0.324292236320171 7.81805675919961e-05 843.180779191532 230.908141803381 3.65158531269764 0.000355234836068675 -204.604070487558 374.990079872484 -0.545625288426654 0.586102880110576 HNRNPA0 other 0.581585242316859 1 1 3.65158531269764 -0.545625288426654 0.796427588046973 3.90967696572043 12.4065462949186 0.315130163768601 0.753112780040733 -11.4285894034098 28.0267857197078 -0.40777381743685 0.684037065471505 MYOZ1 other 1 1 1 0.315130163768601 -0.40777381743685 0.0101657144499609 238.298016040523 124.351988713224 1.91631849644221 0.0572013722656125 -224.382756437316 216.924874832526 -1.03438002032062 0.302601432073302 CHID1 other 1 1 1 1.91631849644221 -1.03438002032062 0.00862559755415799 19.8865621278285 9.51838672452649 2.08927864599006 0.038382532158052 -33.1040628068782 22.6087645186793 -1.46421370258989 0.145242201993825 PCDHB9 other 1 1 1 2.08927864599006 -1.46421370258989 4.27142813615311e-08 37.507532623018 7.84921941173071 4.77850479844693 4.02720463525497e-06 -24.7534893641908 17.1970718409583 -1.43940140467607 0.152027654389596 ZNF620 other 0.000436710812640294 1 0.0422896758748125 4.77850479844693 -1.43940140467607 1.38368749468231e-10 233.292257476714 36.0665539034527 6.46838226078428 1.17967150067655e-09 59.5985882477821 63.8818115916518 0.932950815934133 0.352268858723445 ZNF518A other 1.6276315999948e-06 1 1.4843806493013e-05 6.46838226078428 0.932950815934133 0.000151856651183956 80.5687798589519 23.8944214795704 3.37186568537923 0.000948356844991967 -166.352189139442 106.431966214888 -1.56299084810267 0.120148111697317 SVBP other 1 1 1 3.37186568537923 -1.56299084810267 1.09534277775787e-06 26.9650753950369 9.40433929795115 2.86730141700774 0.00470879424732814 -61.2641939800941 20.6042269989181 -2.97337987895936 0.00341033655715802 ZNF619 other 0.00995885653537457 1 1 2.86730141700774 -2.97337987895936 0.397789864544265 2.63724228957131 4.7317185403964 0.557354007229342 0.578116338954199 -12.8835123801249 13.6468250666289 -0.944066646800471 0.346653731525145 CCDC184 other 1 1 1 0.557354007229342 -0.944066646800471 1.97093628436348e-06 199.512501024177 60.0654405723599 3.32158557604897 0.00112105836088003 -126.965469315667 90.56557297234 -1.40191758467033 0.162978658493282 AP3S1 other 0.0174960013962946 1 1 3.32158557604897 -1.40191758467033 1.0566299227227e-08 511.690127380136 83.828426215139 6.10401686495848 7.96248217667805e-09 762.707144364154 388.272867706851 1.96435859365791 0.0512768827681075 GRB2 essential 0.000112457122675376 1 9.73015321990058e-05 6.10401686495848 1.96435859365791 4.87229391040634e-08 120.599353962402 21.2130817288496 5.68514068365598 6.26104148521217e-08 -108.424524317723 78.7072225102267 -1.37756765973586 0.170309923734007 ZBTB41 other 0.000495902074201158 1 0.000735734984927282 5.68514068365598 -1.37756765973586 3.39746916558961e-10 109.940799210657 115.579149539724 0.951216544233794 0.34299468610557 -1238.27927782627 234.610790682059 -5.27801502320652 4.40059706466903e-07 UBE2N essential 3.92985258383751e-06 0.00642487171441679 1 0.951216544233794 -5.27801502320652 0.00140739385145154 158.490515977911 42.8312374531849 3.70034875016495 0.00029741068352418 158.870655473841 129.779324286221 1.22415998347672 0.22272569558328 ARL6IP6 other 1 1 1 3.70034875016495 1.22415998347672 0.0206908009168232 46.0901794616152 18.5982108063184 2.47820502421432 0.0142836505664838 -1.51657300824795 30.3965251227303 -0.0498929730330873 0.960272329019888 ZNF354C other 1 1 1 2.47820502421432 -0.0498929730330873 0.364120087311427 88.8764928633851 62.7888225961993 1.41548271154817 0.159433702568114 82.6316718356439 97.489988931119 0.847591355190601 0.398298627902679 MAMDC4 other 1 1 1 1.41548271154817 0.847591355190601 1.48435573362087e-16 155.441876180676 20.810082502269 7.46954636838792 9.01544131473277e-12 -18.9733071216845 36.7906444507165 -0.515710105244298 0.606900445887503 CENPBD1 other 2.03683293767455e-12 1 1.2027500257985e-07 7.46954636838792 -0.515710105244298 0.00139876288690137 136.601205203541 75.3600475087192 1.81264754627094 0.0718992544903039 -227.222281285035 130.191822870405 -1.74528842346124 0.0829961998417825 BET1L other 1 1 1 1.81264754627094 -1.74528842346124 6.22872519980648e-08 353.945915703095 90.3181208659721 3.91888042299213 0.000134830740293214 -393.196008951884 152.647594571814 -2.57584149986001 0.0109656306607049 IMP3 essential 0.000629848692204431 1 1 3.91888042299213 -2.57584149986001 2.02532432880201e-09 72.5563690041302 18.3127484803733 3.962068778583 0.000115172926837497 -190.803599385689 52.8079325762513 -3.6131616989584 0.000413755973921937 ASB8 other 2.25094545903056e-05 1 1 3.962068778583 -3.6131616989584 0.247346434883872 156.241642852396 104.78929550651 1.49100766540308 0.13824176394656 55.3784807602848 167.286200886873 0.331040339649619 0.741116143374928 ODF3B other 1 1 1 1.49100766540308 0.331040339649619 0.359281057442282 3.24421220469021 4.21284753751971 0.770075863367282 0.442450072873523 -10.5509065506871 11.7670495475803 -0.896648434089136 0.371324451454165 DPY19L2 other 1 1 1 0.770075863367282 -0.896648434089136 0.886960595623546 -1.54959387463973 3.48259345754193 -0.444953995788375 0.65697776314134 -4.08654857908111 14.7642203784436 -0.276787292138206 0.782314591725163 C2orf73 other 1 1 1 -0.444953995788375 -0.276787292138206 2.76642843626847e-28 185.123473874567 13.2165497054956 14.0069441722442 3.75285930689985e-29 4.32187247558148 72.8632724408837 0.0593148280443752 0.952779262054191 LRRC75B other 4.00329859012411e-24 1 5.44239656686616e-25 14.0069441722442 0.0593148280443752 1.05756127675439e-12 175.993263836587 26.7849700715612 6.57059774068766 7.64438896535416e-10 -300.708444488242 108.438640268581 -2.77307465072826 0.00625322827243412 DMAP1 essential 1.34183374794597e-08 1 9.68314750241411e-06 6.57059774068766 -2.77307465072826 0.770052243648055 0.197136146677766 12.1282729137924 0.0162542637421674 0.987052584123805 -17.0078557087658 28.1994192492959 -0.603127871478789 0.547310848980589 ADAMTSL1 other 1 1 1 0.0162542637421674 -0.603127871478789 9.90431826312238e-06 777.613503903815 267.721532952318 2.90456092690277 0.0043445719353341 -1429.39638087558 573.362955529184 -2.49300441734384 0.0139637500743327 IMPDH2 essential 0.0818690947629696 1 1 2.90456092690277 -2.49300441734384 0.2667114769748 -73.0983638368248 101.385304747925 -0.720995651377387 0.472073044236427 -368.824196251379 225.955386121106 -1.63228769441105 0.104788717801826 ALS2CL other 1 1 1 -0.720995651377387 -1.63228769441105 1.17891336271899e-06 413.79334511285 75.6674010205081 5.46858144368801 1.82340063821878e-07 70.1102573662515 299.38609688453 0.234180070804331 0.815160316194402 MLF1 other 0.0106915652864985 1 0.00208742905063286 5.46858144368801 0.234180070804331 0.00105441564442673 110.096202485246 105.462853149862 1.04393347227957 0.298514895576154 -649.521357965861 225.863390642226 -2.87572658906339 0.00473444576796921 NDUFAF3 essential 1 1 1 1.04393347227957 -2.87572658906339 0.000746330685005238 48.1610055865921 17.6592459305783 2.72724021036469 0.00712829639227704 -90.6371694599628 53.2288797058933 -1.70278183498812 0.0906263663597144 C2orf69 other 1 1 1 2.72724021036469 -1.70278183498812 4.19310809683173e-07 223.588434120609 89.8196565901024 2.48930404110727 0.013862393060309 -341.670478436822 135.333864949453 -2.52464879034109 0.0125937345481591 STAP2 other 0.00395535886774137 1 1 2.48930404110727 -2.52464879034109 1.28937256229471e-16 28.5568700140488 3.22028363859717 8.86781203735483 1.9637654878976e-15 4.68650010211721 10.4776453792098 0.447285619287741 0.655309794804023 TSSK6 other 1.77082427705556e-12 1 2.74750429411754e-11 8.86781203735483 0.447285619287741 4.24109927182491e-18 177.87670461742 22.9741557330884 7.74246969873341 1.15056861394173e-12 -113.956501275189 60.5087364460138 -1.8833065763464 0.0615201387511724 DDX10 other 5.91845403383167e-14 1 1.56063126795057e-08 7.74246969873341 -1.8833065763464 2.54537720858474e-05 35.1709187152119 10.3132280910349 3.41027255528123 0.000839429784594774 -64.8429655249359 36.3543146288326 -1.78363878364822 0.0765597516050918 PPP1R42 other 0.2015809764716 1 1 3.41027255528123 -1.78363878364822 4.79107268155681e-08 167.796933485697 65.5680022953347 2.55912834937227 0.0114766769169102 -621.967485978343 175.82777847691 -3.53736759553053 0.000537166810725015 NDUFV2 other 0.000487827020436114 1 1 2.55912834937227 -3.53736759553053 1.78901294688439e-13 445.624225651552 76.138458938203 5.85281383240549 3.92983324961496e-08 -537.437752770548 163.061115648178 -3.29592834339566 0.00127445450857635 DALRD3 other 2.31909748304623e-09 1 0.000466078223404335 5.85281383240549 -3.29592834339566 0.11417377377314 13.9638705998017 9.40299418351013 1.4850451172553 0.139536965252927 -4.80294176480349 16.3607868148132 -0.293564228858167 0.76947861645511 ZNF114 other 1 1 1 1.4850451172553 -0.293564228858167 2.8200515302484e-07 213.942363112391 40.8451595653292 5.2378878033321 5.40647902251994e-07 79.9390009606144 76.6691168551532 1.04264929921703 0.298788257636814 ZNF518B other 0.00269709728352957 1 0.00601146402513992 5.2378878033321 1.04264929921703 9.2469901764311e-12 154.896912626454 23.7685776584307 6.51687765470946 1.02662028902572e-09 25.7626891344272 43.4190719021413 0.593349604351094 0.553840830392456 LCORL other 1.1384894305222e-07 1 1.29497883257704e-05 6.51687765470946 0.593349604351094 2.67979410045206e-06 120.853550758153 32.2759886811852 3.74437951233399 0.000286192359867514 -5.03580134255045 59.1671136418271 -0.0851114923914505 0.932323367103849 PARD6G other 0.0234481983789556 1 1 3.74437951233399 -0.0851114923914505 0.000593405616830226 17.33444666002 4.81722404765229 3.59843064979883 0.000430945012555799 1.71360010876463 7.87316980709446 0.217650596995953 0.827989473547068 ZNF454 other 1 1 1 3.59843064979883 0.217650596995953 5.40704981578937e-05 199.366087107066 79.4810882090737 2.50834621919918 0.0131792449504601 -369.559270892587 168.087548120621 -2.19861182475807 0.0294171247673094 SH2B1 other 0.409908446534992 1 1 2.50834621919918 -2.19861182475807 0.203485426653785 5.33538483106686 2.98746517285985 1.78592369194363 0.0760666995161138 5.37964741343054 6.1356794933729 0.876781034478913 0.381962449792845 ZC3H12D other 1 1 1 1.78592369194363 0.876781034478913 9.35055069929294e-05 16.0258748481166 4.50001278426023 3.56129540435321 0.000491316073011046 -1.92356925880917 9.08301766307898 -0.211776452514034 0.83256145721839 VN1R1 other 0.688294036974954 1 1 3.56129540435321 -0.211776452514034 0.0405933396075234 81.201093432961 47.0733699172898 1.72499002250392 0.0865225147210536 -98.0847450803565 124.664226168532 -0.786791432433527 0.432605291288125 KDELC2 other 1 1 1 1.72499002250392 -0.786791432433527 5.70347844338949e-10 6213.87122943327 901.696524859966 6.89131105434646 3.62805092959603e-10 132.832304996947 3797.76699560335 0.0349764230271963 0.972161932168525 PLEC other 6.51850551294985e-06 1 4.63955152876741e-06 6.89131105434646 0.0349764230271963 2.32089857230186e-05 477.124424268008 105.326625748264 4.52995072118193 1.2714819156686e-05 245.572906099766 189.230751508104 1.29774312125611 0.196556399193792 RNF212 other 0.184627481426613 1 0.127822076982165 4.52995072118193 1.29774312125611 0.0399022157745858 5.01009509875641 5.32671998256696 0.940559127409217 0.348443045040431 -19.0566203365033 11.0363197029243 -1.72671876580867 0.0862768975453795 PRSS36 other 1 1 1 0.940559127409217 -1.72671876580867 8.89055315644075e-11 39.2296772388116 6.59162312013154 5.95144420787648 1.70992592824222e-08 -4.0078629504466 13.117876369392 -0.305526812236023 0.760374879243576 ZNF543 other 1.05521975413795e-06 1 0.00020599477657534 5.95144420787648 -0.305526812236023 0.0137347248341409 11.7090051718892 4.96849840338918 2.35664867355137 0.0197875450199684 -8.59713590334218 15.0040818617687 -0.572986470118387 0.567547503904781 TMEM151B other 1 1 1 2.35664867355137 -0.572986470118387 8.74789365033902e-10 199.226944667201 30.9584322549487 6.43530470233532 1.47989938291113e-09 -45.0329835082459 97.5746196753844 -0.461523536121008 0.645074274585909 GALNT11 other 9.90261561218377e-06 1 1.85801367524492e-05 6.43530470233532 -0.461523536121008 5.42056442549971e-16 1889.24887292545 224.866018178159 8.40166463671096 8.24239507624107e-14 -408.139311369832 482.169904583752 -0.846463679068005 0.398911717455074 WDR6 other 7.387145199071e-12 1 1.13398871458925e-09 8.40166463671096 -0.846463679068005 4.00365420461322e-09 117.045934549796 19.6481493304688 5.95709715867694 1.69828470545942e-08 -50.8405444232995 62.5018644651955 -0.813424445147718 0.417238795654832 GEN1 other 4.37118966059671e-05 1 0.000204609341313751 5.95709715867694 -0.813424445147718 0.106899631030626 12.4711162741578 6.09883002295147 2.04483748968667 0.0427049455819074 3.69864822050903 9.06032406661418 0.408224716170798 0.68371930494756 TMPRSS9 other 1 1 1 2.04483748968667 0.408224716170798 0.00495168308669043 10.6250286647939 3.20690955397127 3.31316754837579 0.00115793961477471 7.27423608324253 11.8842977862814 0.612088001668852 0.541412445709654 AQP11 other 1 1 1 3.31316754837579 0.612088001668852 1.89285357291486e-05 107.139798527944 30.3217366041429 3.53343213572093 0.00053991538014044 -116.453124999999 73.7956114724013 -1.57804946224413 0.116579880425069 TMEM11 other 0.151825785083501 1 1 3.53343213572093 -1.57804946224413 0.00218140465209964 26.2844965104686 11.1794096738374 2.35115245592806 0.0199820327038329 -23.7326701713042 18.2713923692405 -1.29889773541603 0.195920468337047 ZNF354B other 1 1 1 2.35115245592806 -1.29889773541603 0.204643779694216 -24.4157748298823 20.1861288081211 -1.20953230121367 0.228311924733993 -62.3985494409304 34.9511306908879 -1.78530846377449 0.0761795228735192 SHISA3 other 1 1 1 -1.20953230121367 -1.78530846377449 0.113045443436409 140.543649727116 67.877679949896 2.07054292119087 0.040049332983214 113.171713939047 265.879267806236 0.42565076575103 0.670948987274214 CALML5 other 1 1 1 2.07054292119087 0.42565076575103 3.27875169495604e-06 30.9587878441023 19.9851176984306 1.54909209499094 0.123554565267053 -100.201430778916 37.5178492352382 -2.67076692351551 0.00843870841569457 ZFAND2A other 0.028416940940184 1 1 1.54909209499094 -2.67076692351551 5.17060953532768e-15 170.913799701628 20.3941152089273 8.38054497342512 2.9843971355072e-14 5.8305182590647 58.4912045003584 0.0996819660130092 0.920725627136213 PLEKHM3 other 6.93327032592089e-11 1 4.12682435897936e-10 8.38054497342512 0.0996819660130092 1.53963783923321e-11 12.9021759579446 2.27469527992111 5.67204586558603 6.6709096268046e-08 -29.4168669415364 9.95700355781976 -2.95438951796234 0.00361861694637494 ZNF223 other 1.88035969305551e-07 1 0.000782230862839107 5.67204586558603 -2.95438951796234 2.9276106963465e-13 64.9302318857342 20.9875189543463 3.09375453225202 0.00235800152226923 -148.434684554444 40.7284953314658 -3.64449222458182 0.000368646650703246 FAM220A other 3.77310466545137e-09 1 1 3.09375453225202 -3.64449222458182 0.0195648826231446 21.8737029463001 28.936574799292 0.755918870772337 0.450891251118912 -177.345287687142 78.6403143743275 -2.25514469389045 0.0255812157327853 DNAJC22 other 1 1 1 0.755918870772337 -2.25514469389045 0.217570887528612 55.596613756614 32.6112954620135 1.70482690027983 0.0902046779455963 58.6576719576732 131.925212363325 0.444628217054741 0.657200780489146 CEP295NL other 1 1 1 1.70482690027983 0.444628217054741 3.43191783943291e-07 142.766397820789 27.4171915317785 5.20718534045738 6.22069912709969e-07 71.2460866925393 57.2240530323048 1.24503740852328 0.215059559170318 BEND3 other 0.00325798865219001 1 0.00689004635317562 5.20718534045738 1.24503740852328 1.30469902893587e-09 73.7645222031924 25.2407640681891 2.92243618314857 0.00398617599307049 -158.04258174604 52.3578211680934 -3.01850952198045 0.00296515379276258 NT5DC1 other 1.46413325027184e-05 1 1 2.92243618314857 -3.01850952198045 1.25484323384022e-05 814.913783482145 205.652902911475 3.96256883294729 0.000113419341134303 -126.258984375 487.974014368419 -0.258741204771766 0.796182688353905 GLDC other 0.10264617652813 1 1 3.96256883294729 -0.258741204771766 0.0120813867364807 63.1296835383604 46.3511854454774 1.36198638571217 0.175191111159595 -230.294064078513 118.051937522146 -1.95078597532812 0.0528977886720293 COX14 other 1 1 1 1.36198638571217 -1.95078597532812 0.0040049609834387 65.9927479638514 24.6001938592438 2.68261089085092 0.00814757644918587 -76.9223474283164 86.7161260853566 -0.887059315271995 0.376505862409683 MCMDC2 other 1 1 1 2.68261089085092 -0.887059315271995 1.85936587057205e-07 -74.506762447362 94.5723841000265 -0.787827896657002 0.432288782391122 -1147.08586821898 202.787232091419 -5.65659808257482 9.98116951244823e-08 P4HTM other 0.00180972080182778 0.00145864811254918 1 -0.787827896657002 -5.65659808257482 1.80868093332913e-07 212.246985724824 41.8751307720799 5.06856890501554 1.30423845977294e-06 -219.058770338873 142.650567916523 -1.53563195392998 0.126986497173541 DTX3 other 0.00176219783334257 1 0.0141483788116168 5.06856890501554 -1.53563195392998 4.20660390939661e-09 46.2688958675326 6.99221060000929 6.61720570422623 5.72005680090963e-10 26.8256369995004 28.111651643282 0.954253323138025 0.341450889346135 KLHL11 other 4.58519826124231e-05 1 7.27591225075705e-06 6.61720570422623 0.954253323138025 2.12278762607527e-14 1398.68108543794 187.176973865974 7.47250613443217 5.64112073245646e-12 15.7783449758197 520.524437446769 0.0303124000348846 0.97585741215316 CTXN1 other 2.81566550722624e-10 1 7.5607941177114e-08 7.47250613443217 0.0303124000348846 0.00200758909402939 22.1975443383356 22.1086659668649 1.0040200693974 0.317278084817427 -132.605306086906 47.6875380116502 -2.78071193473042 0.00625004954429091 SLC25A20 other 1 1 1 1.0040200693974 -2.78071193473042 0.950126834301296 -0.385629680492682 3.68822523517698 -0.104556976839344 0.916861663401529 2.66512885436557 10.9879030095146 0.242551181245212 0.808671702513237 CD28 other 1 1 1 -0.104556976839344 0.242551181245212 9.5830602598696e-09 332.808915283294 69.2791173871234 4.80388503542268 3.64241520069164e-06 -271.21682381507 152.053352091432 -1.78369513124566 0.0764298835658414 EPM2AIP1 other 0.000102260836033068 1 0.0383728441392865 4.80388503542268 -1.78369513124566 8.98039420376539e-07 407.901666473117 82.1888487622955 4.96298065511101 1.85217349191011e-06 -100.16081175241 235.484323850743 -0.425339615455229 0.671194670930342 ERBB4 other 0.00822334697238797 1 0.0199071606910498 4.96298065511101 -0.425339615455229 0.168971097985166 -128.880629848327 67.9549489497781 -1.89655988033448 0.0597585591233169 -152.542838948709 124.126520346542 -1.22893027632478 0.22097250016718 MAF other 1 1 1 -1.89655988033448 -1.22893027632478 8.98385919075535e-08 215.705907548243 50.2695161395254 4.29098833872881 3.15273824110302e-05 -112.623235222955 109.024645551931 -1.03300712103035 0.303241356003838 CTNNBIP1 other 0.000897577371748367 1 0.305058952209128 4.29098833872881 -1.03300712103035 0.000169547303095952 77.3499026966917 18.1374355565591 4.26465486013646 3.49165764565087e-05 -24.195280789548 72.6014247002424 -0.333261790515073 0.739392932261038 ERN1 other 1 1 0.335757799205788 4.26465486013646 -0.333261790515073 0.0536322196779947 46.7258883248731 20.6293536415207 2.26501950263861 0.0250144249605053 9.93387151815041 45.0859850304199 0.220331695347189 0.825927083634522 GPR35 other 1 1 1 2.26501950263861 0.220331695347189 1.81792958931018e-08 74.1711190959746 13.2496794813321 5.59795572417254 9.45444973040587e-08 -47.9354180770367 40.2939179828358 -1.18964400774966 0.235982300937539 CSRNP3 other 0.000190937144765248 1 0.00109983613713811 5.59795572417254 -1.18964400774966 1.4493378284496e-05 37.8874193107133 10.136280170685 3.73780308680564 0.000262831004502518 -29.4171611701331 25.9423078401483 -1.13394542040732 0.258614479164249 ZNF713 other 0.117645843578931 1 1 3.73780308680564 -1.13394542040732 0.0012275024491235 663.540413533836 203.488596086861 3.26082358566471 0.00148292447529585 -722.99655388471 849.468419030662 -0.851116460232542 0.39657058805091 PARP10 other 1 1 1 3.26082358566471 -0.851116460232542 8.85514821052487e-15 293.560362794288 32.709006996868 8.97490904637971 9.61282436130903e-16 177.378270937863 127.480546500659 1.3914144220973 0.166119596191426 SUZ12 og 1.18278214647981e-10 1 1.34819861667359e-11 8.97490904637971 1.3914144220973 0.234250597755787 515.220819087867 569.686491219367 0.904393604252541 0.367276631666317 -927.037757665347 1046.88626768003 -0.885519073356196 0.377332864068797 KCTD12 other 1 1 1 0.904393604252541 -0.885519073356196 0.0483455382371901 168.176485342392 72.9885113947832 2.30415009333116 0.02262485118661 15.5842449417831 125.546529946483 0.124131228066807 0.901382108537713 RPP25 other 1 1 1 2.30415009333116 0.124131228066807 8.15244532507916e-07 2314.07119360902 422.268068035217 5.4800998909916 2.76607501849586e-07 522.134946741855 1762.76899570279 0.296201571513167 0.767639753076999 GRINA other 0.00749128200921524 1 0.00313009049092992 5.4800998909916 0.296201571513167 0.0143544478810881 -52.3171357987318 27.3672801931566 -1.91166734251561 0.0578130400282992 141.928624714169 100.251435752178 1.41572660430537 0.158914862346228 THBD other 1 1 1 -1.91166734251561 1.41572660430537 0.00957591446245816 561.440820022735 329.74146894937 1.7026697364199 0.0907725965586449 -890.05357314888 546.071060929754 -1.6299226178246 0.105288296056038 COX5A other 1 1 1 1.7026697364199 -1.6299226178246 0.254484285770484 -19.713055847303 36.7117235580778 -0.536968955328861 0.592117760923772 -132.557963044132 80.801092377717 -1.6405466701424 0.103074102324906 ERFE other 1 1 1 -0.536968955328861 -1.6405466701424 4.6246493166458e-11 289.546078110248 46.8557355564505 6.1795226277349 6.16342660595884e-09 -97.6318182693975 77.5958247152819 -1.25820968625094 0.210338205057398 FAM219B other 5.54819178517997e-07 1 7.57176958542044e-05 6.1795226277349 -1.25820968625094 8.49747380317722e-05 287.845325000786 70.0059666441857 4.11172559710227 6.40735653128468e-05 -229.987746542378 394.283147781609 -0.583306052608079 0.560551763811271 ZHX2 other 0.628983010911178 1 0.598831541413866 4.11172559710227 -0.583306052608079 0.349650560396216 -4.26768995816809 28.1624366291645 -0.151538377675338 0.879773959612829 -61.9779332020095 49.6836090640153 -1.2474523161583 0.214359864078189 CPNE7 other 1 1 1 -0.151538377675338 -1.2474523161583 0.00633777733535623 11.8849527900214 7.2409948133409 1.64134253599028 0.102753872053683 34.8126462759547 10.7907215985876 3.22616480815439 0.00153067588000017 C5orf46 other 1 1 1 1.64134253599028 3.22616480815439 6.18214198073465e-12 497.26066350711 80.4717124737934 6.17932250005303 6.25311802245775e-09 -244.091627172196 133.959423000369 -1.82213107301547 0.0705099814462004 MPI other 7.65410998634757e-08 1 7.6813301787871e-05 6.17932250005303 -1.82213107301547 0.0493622187605257 14.1086512866016 6.82178503606991 2.0681758824124 0.04040012840681 -26.6486448334275 27.9153487837553 -0.954623388009933 0.341356953136899 TRIM73 other 1 1 1 2.0681758824124 -0.954623388009933 0.000158695396179508 343.328242481203 78.985761627425 4.34671053880164 3.11666959739822e-05 333.527020676691 329.728109318426 1.01152134516562 0.3140071156997 OPLAH other 1 1 0.301662450332173 4.34671053880164 1.01152134516562 0.249680619929117 7.65411318115978 11.3941931637553 0.671755610174083 0.502878800278811 -23.4254912342041 25.4770453499749 -0.919474409705329 0.359475440362659 TMEM52 other 1 1 1 0.671755610174083 -0.919474409705329 0.00012190045025186 218.892986121475 71.7315944076619 3.05155612291944 0.00269909002834732 -647.4795702134 294.194832997205 -2.20085296406124 0.0292957912590343 TMEM139 other 0.884997268828502 1 1 3.05155612291944 -2.20085296406124 3.52782885445893e-05 25.601402496969 5.53656154422465 4.62406175610466 7.84754538922325e-06 -10.0176786709036 22.9699961723921 -0.436120171536813 0.663352476929955 EFCAB13 other 0.27404174541437 1 0.0803902549672029 4.62406175610466 -0.436120171536813 0.098059459913369 22.1233879276654 15.7831625622341 1.4017081709975 0.163110327849578 108.518643194657 51.9174560147122 2.09021495898999 0.0383203013990617 MSC other 1 1 1 1.4017081709975 2.09021495898999 1.72471689058404e-20 352.369905650702 37.5000938441768 9.39650730248558 7.70018025945348e-17 -341.113255050764 150.13388142712 -2.27206045569634 0.0244762895769132 APOLD1 other 2.44254406044511e-16 1 1.08788146705559e-12 9.39650730248558 -2.27206045569634 0.121106809862575 20.7926108374386 37.5054957804512 0.554388374417283 0.580144235183627 -126.187243971999 86.0133123833433 -1.46706643978096 0.144465523369202 RFLNA other 1 1 1 0.554388374417283 -1.46706643978096 7.18378829970267e-12 160.992426796691 22.6503784933624 7.1077146390233 4.74224405958447e-11 -87.417580897546 109.697357884203 -0.796897779341456 0.42679561390907 DPY19L3 other 8.87413368662271e-08 1 6.23367981632379e-07 7.1077146390233 -0.796897779341456 0.000128477256238024 253.766141285968 131.44914172067 1.93052718309277 0.0554666152694917 -565.260596923927 221.30821534574 -2.55417809971874 0.0116615534857621 TAF7 other 0.928505130832202 1 1 1.93052718309277 -2.55417809971874 2.98151460280389e-10 10.9573358598104 2.04118808315734 5.36811671115648 2.87572479367416e-07 -9.74347057375399 4.51511898105008 -2.15796540792109 0.0324804044201229 ZNF852 other 3.45617172757027e-06 1 0.00324985658933116 5.36811671115648 -2.15796540792109 0.869112680181673 -2.94547964113181 5.55841061173495 -0.529914007236762 0.59692980514685 -2.32751035196687 8.34869581075351 -0.278787298606439 0.780779663293425 FOXE1 other 1 1 1 -0.529914007236762 -0.278787298606439 3.85565235164653e-17 338.8006910066 36.393699689914 9.30932259960627 1.42421296656858e-16 -179.152083333332 195.108723732069 -0.918216673793377 0.35996978593999 PFAS other 5.32658372379969e-13 1 2.00842512545501e-12 9.30932259960627 -0.918216673793377 3.21620793198045e-13 197.298644018372 25.1609049501342 7.84147646554818 7.46764564472109e-13 -53.696925513795 114.156414052684 -0.470380275689227 0.638762053811428 HYI other 4.14054609163163e-09 1 1.0159731899643e-08 7.84147646554818 -0.470380275689227 0.0235963362575141 232.0602711996 86.6047111236345 2.67953403676063 0.00831873061306659 384.658047251955 418.493352947389 0.919149717774162 0.359706608125142 C17orf62 other 1 1 1 2.67953403676063 0.919149717774162 7.67175704995029e-10 48.3965327596779 11.9641877936159 4.0451164420457 8.27035409048364e-05 -57.6483603126554 23.5015471244184 -2.45296022459551 0.0152919297334464 ZNF552 other 8.71204730592355e-06 1 0.763105571928925 4.0451164420457 -2.45296022459551 3.07066812484973e-11 749.119871451526 124.316184853583 6.02592391597137 1.64549572333671e-08 -85.7559400107124 225.973395084578 -0.37949573656056 0.704943763237334 GAK essential 3.70844589438102e-07 1 0.000198348054491007 6.02592391597137 -0.37949573656056 0.00112026074073721 81.5532670454537 123.848434100259 0.658492516582275 0.511217891210714 -512.498266209895 185.148937282517 -2.76803244853563 0.00634119023309601 ZBTB7A other 1 1 1 0.658492516582275 -2.76803244853563 0.195986368221766 -30.3451131971286 18.6234274736322 -1.62940539490341 0.105232019343005 -70.1707658445304 55.0546735206635 -1.27456510696033 0.204346413809769 ERICH3 other 1 1 1 -1.62940539490341 -1.27456510696033 4.77139854303272e-06 125.636384669624 43.813279968038 2.86754118297641 0.00472874665464916 -127.798671298881 59.419121707932 -2.15080040945507 0.0330830995079111 RMI1 other 0.0406332299924666 1 1 2.86754118297641 -2.15080040945507 9.53300195649736e-09 170.863603547854 27.9436947100697 6.11456735842031 7.91308040342461e-09 -74.4104166666672 149.807759521389 -0.49670602447027 0.620118727782786 CTC1 other 0.000101793394891479 1 9.6721581771059e-05 6.11456735842031 -0.49670602447027 1.14907409727234e-06 298.180604378661 74.4703712346966 4.00401662345595 9.55805785032745e-05 -160.50309384315 115.746094781572 -1.38668258437609 0.16749195788827 FBXO34 other 0.0104324437291355 1 0.876569485453531 4.00401662345595 -1.38668258437609 0.00432852854937142 8.75716790429041 2.92127447142527 2.99772171014723 0.00318144203704729 -11.1104166666668 15.6611209810257 -0.709426654715692 0.479153739065167 LINC00324 other 1 1 1 2.99772171014723 -0.709426654715692 0.0876811528193313 -142.279376961239 336.713261226205 -0.422553529501931 0.673199180739083 -1158.76555405571 583.48520021844 -1.98593820995272 0.0487811681042937 SELENOW other 1 1 1 -0.422553529501931 -1.98593820995272 1.11905951438663e-15 1131.59888992869 138.206428898999 8.18774422393663 9.44784880163936e-14 -253.91089311261 532.239319877047 -0.477061509043087 0.633994617611685 EIF3K other 1.51778041936259e-11 1 1.29926816720145e-09 8.18774422393663 -0.477061509043087 4.03742467856664e-16 401.916221033867 55.7132279621559 7.21401785060588 2.30613387879287e-11 -89.6603249691482 106.151775255385 -0.844642727391405 0.399620605052648 MRFAP1L1 other 5.51027720130776e-12 1 3.05378248229752e-07 7.21401785060588 -0.844642727391405 0.000389138861529617 85.9784661798781 50.7638257594453 1.6936955576852 0.092344792463096 -129.291242184426 75.1124024208808 -1.72130351336604 0.0872039231760506 SNX18 other 1 1 1 1.6936955576852 -1.72130351336604 2.21302960315042e-08 214.90305280528 34.1291234258037 6.29676450004575 3.1443247690692e-09 334.083333333334 182.968199727939 1.82590927729568 0.0698393959543786 AURKB essential 0.000230973899680809 1 3.90022044355343e-05 6.29676450004575 1.82590927729568 0.0162411939284785 4.04336819833371 11.8279541601437 0.341848483988763 0.732922066441927 -38.4140003652325 16.3721725187411 -2.34629828883493 0.0202102412111392 C14orf39 other 1 1 1 0.341848483988763 -2.34629828883493 6.06884713970885e-15 1154.97237076649 184.239228883294 6.26887323490754 3.48779178240753e-09 -585.920917317975 351.035506880513 -1.6691215157258 0.097124966113941 MRFAP1 other 8.13043451306795e-11 1 4.32137401840292e-05 6.26887323490754 -1.6691215157258 0.655344849640112 -20.2468625381187 28.0682798216323 -0.721343191203132 0.471945807042876 -56.3447722000679 67.8271952000172 -0.830710632127888 0.40760386246032 C3orf38 other 1 1 1 -0.721343191203132 -0.830710632127888 0.01679092131428 -19.3119708365915 6.7709198930309 -2.85219307593179 0.00493450184117812 -30.5137758288 15.0083604032822 -2.03311854252427 0.0437468688271859 KLHDC7A other 1 1 1 -2.85219307593179 -2.03311854252427 0.312246275749666 24.0587997575267 15.8519225625192 1.51772125195792 0.131161804560501 15.3591836734692 85.4946370389439 0.179650843671901 0.857665954262425 TMEM107 other 1 1 1 1.51772125195792 0.179650843671901 1.54133797470966e-05 112.498559504312 31.1480054345613 3.6117420019288 0.000418395496635191 -192.504719432221 113.007209940104 -1.70347289818279 0.090621906389339 RRS1 essential 0.124740482293253 1 1 3.6117420019288 -1.70347289818279 0.440949421201262 12.5222849755035 10.186227607844 1.22933488800708 0.221053454843022 9.5550376519687 16.1437478399793 0.591872330185066 0.554911552315498 EXOC3L1 other 1 1 1 1.22933488800708 0.591872330185066 1.84681823889211e-13 1610.77541812699 244.639307160006 6.58428703394532 6.70078364250495e-10 -341.64759615655 542.265297577324 -0.63003772818015 0.529597591875762 RCC2 other 2.39292239213251e-09 1 8.50061412888178e-06 6.58428703394532 -0.63003772818015 0.136312055220204 -0.305668626564155 2.31320039426327 -0.132141005734831 0.895044140271343 -6.40012060907584 3.6936350424313 -1.73274309333578 0.0851303263563997 IGSF22 other 1 1 1 -0.132141005734831 -1.73274309333578 0.0223931846421108 0.5284004202837 4.2342543026287 0.124791848225946 0.900847981876765 -12.7732281790208 5.83738120798993 -2.18817783589967 0.0301345308830852 C9orf50 other 1 1 1 0.124791848225946 -2.18817783589967 0.472998893687414 20.82965380851 17.0884636508888 1.21893074965968 0.224710460948246 18.8656401666886 28.9826960197808 0.650927717484 0.516050780974797 ZFP42 other 1 1 1 1.21893074965968 0.650927717484 0.00281034783227818 11.668306997058 4.98710857249539 2.3396937980076 0.0205585282790947 -27.4549225076583 17.5166808452874 -1.56735872224586 0.119044186064061 CCDC89 other 1 1 1 2.3396937980076 -1.56735872224586 0.0214993774748838 1175.52866541353 438.371309204137 2.68158212166692 0.00846703401099152 2986.57221177945 1829.99239337759 1.63201345677027 0.105562475531847 CYC1 essential 1 1 1 2.68158212166692 1.63201345677027 1.48045054290058e-06 119.899395933384 30.8177954159846 3.8905896516918 0.000149926253382338 -64.8562224167975 65.0310552975389 -0.997311547845232 0.320219426204908 TMTC2 other 0.0133003676774188 1 1 3.8905896516918 -0.997311547845232 2.2288638997913e-22 540.326213652276 52.0908055648084 10.3727751528057 2.58764428670446e-19 -373.782099671935 264.838796374866 -1.41135703978531 0.160224078240053 FARSA essential 3.18304053529195e-18 1 3.69774368570068e-15 10.3727751528057 -1.41135703978531 2.17449411235633e-08 17.4526758898664 8.11162244930896 2.15156412899286 0.0329705042969572 -250.356950757532 47.0382033809783 -5.32241737061696 3.50693057449765e-07 SPTY2D1 other 0.000227038930271125 0.00512152141099638 1 2.15156412899286 -5.32241737061696 0.74365707677796 2.14300335321923 2.81670268324242 0.760819864293355 0.44794331532622 4.72284094428807 11.988112666815 0.393960340176118 0.694162445337776 C10orf67 other 1 1 1 0.760819864293355 0.393960340176118 2.42553455986065e-24 973.408291022914 102.197387608681 9.52478643338857 3.38597951525072e-17 -1044.54210610775 377.897060463309 -2.76409164132456 0.00640508861758762 SAMD4B other 3.48622082288771e-20 1 4.7914996120313e-13 9.52478643338857 -2.76409164132456 0.886358762521997 -2.29288791424088 5.65568852571308 -0.405412692692759 0.685740518494926 2.76444625026435 18.3528530185946 0.150627602556588 0.880467888285301 GIMAP7 other 1 1 1 -0.405412692692759 0.150627602556588 0.0451899143868103 14.5584512022631 5.99464009583121 2.42857802462358 0.0163331041587302 -5.4127652050921 38.3592840252917 -0.141107044686321 0.887973449954552 ALOXE3 other 1 1 1 2.42857802462358 -0.141107044686321 3.6719579427426e-12 334.285735051846 47.4449086696712 7.04576622497611 6.23648301804721e-11 -31.2996010595339 81.4868314490105 -0.384106247634862 0.701443651007113 EDC3 other 4.58040033777712e-08 1 8.1760292366599e-07 7.04576622497611 -0.384106247634862 3.75607421285634e-09 109.718010116376 25.2896382808466 4.33845707470923 2.5851082583762e-05 -157.073223821632 55.7648498486619 -2.81670665747164 0.00548776116452693 TCAIM other 4.10876958144356e-05 1 0.252203161687182 4.33845707470923 -2.81670665747164 6.20328644362076e-06 70.5805731298847 62.819819718447 1.12353988671443 0.262991347560664 -453.66780530597 138.551978300122 -3.2743509755109 0.00131324446728948 FUCA1 other 0.0522378751417305 1 1 1.12353988671443 -3.2743509755109 5.67791977572316e-07 9.7221312118228 2.17865855312556 4.4624391453517 1.56265121793727e-05 -9.98679865110973 8.26257997851242 -1.20867800094901 0.228651228792534 GGN other 0.00529038557427986 1 0.155608808282193 4.4624391453517 -1.20867800094901 1.14134414106941e-12 261.570103718256 35.0097751263201 7.47134486795403 5.80893618589245e-12 -141.119133145222 160.772205714153 -0.87775826995946 0.381460217567234 TMEM125 other 1.44642542997726e-08 1 7.78397448909588e-08 7.47134486795403 -0.87775826995946 3.04130244182793e-11 846.574798409996 219.864859940567 3.8504324822022 0.000173712785496032 -1934.35560477002 500.305892313715 -3.86634583859166 0.000163724002086024 ZNF664 other 3.67328508923978e-07 1 1 3.8504324822022 -3.86634583859166 3.98163479219988e-06 2606.44516355127 612.306795021122 4.25676341459081 3.65351531283642e-05 -3484.12809732384 3113.07519335235 -1.11919175764332 0.264859321889919 CALR other 0.0342500224825034 1 0.350279550162589 4.25676341459081 -1.11919175764332 0.00406988694065948 117.275320675149 42.324999497365 2.77082863716159 0.00628032005792939 -30.1365698870271 70.0395572560968 -0.430279274565286 0.667594039458143 LDLRAD3 other 1 1 1 2.77082863716159 -0.430279274565286 0.510246926332426 6.66842448360071 8.9869933264895 0.74200839383571 0.459343266290766 -20.7185465902568 34.3521935608731 -0.603121502373434 0.547417811024236 CDH4 other 1 1 1 0.74200839383571 -0.603121502373434 6.23428760595697e-26 1204.14539688394 108.094499917124 11.1397471453881 2.21942383244028e-21 -1289.10087957215 560.061539638995 -2.30171291605397 0.0227277502663057 RAD23A other 8.99545358663531e-22 1 3.18753650815074e-17 11.1397471453881 -2.30171291605397 9.43042218083586e-17 760.32392807849 90.8578167645257 8.36828305096749 3.77421515726417e-14 -666.357409668695 470.754467474222 -1.41550947619033 0.15899206932905 GADD45GIP1 other 1.29781470052663e-12 1 5.21143628915036e-10 8.36828305096749 -1.41550947619033 2.57659986539764e-05 8.12996901496408 1.82408116098702 4.45702153437346 1.61736702667983e-05 0.864731503054467 10.3993394673876 0.0831525411557409 0.933841112183418 DAND5 other 0.203912113347569 1 0.160863324473575 4.45702153437346 0.0831525411557409 2.9778062561221e-11 400.581318393796 85.5019656292696 4.68505391011345 6.16566171376737e-06 -457.512944693265 171.25051239781 -2.67160044245867 0.00837198590466127 PTPN11 essential 3.59897664114917e-07 1 0.0637652734437822 4.68505391011345 -2.67160044245867 2.87782850013148e-10 95.8273595736392 21.2003791569181 4.52007762994978 1.22536366174683e-05 -55.9052115479813 35.6790628568813 -1.56689125418548 0.119192628122832 NSUN7 other 3.33828106015251e-06 1 0.123435029531039 4.52007762994978 -1.56689125418548 1.30373175828323e-11 404.927827308847 62.237450961563 6.50617628217012 1.08525019546738e-09 -111.694850922247 106.893085444232 -1.04492119820529 0.29774038242005 CLK3 other 1.5958980453145e-07 1 1.36752377130845e-05 6.50617628217012 -1.04492119820529 0.00467986021967866 -1093.02574751097 345.349364873419 -3.16498554416509 0.00186094412101983 -2398.67822438611 1017.2580985481 -2.35798390576557 0.0195988410251957 HLA-DQB1 other 1 1 1 -3.16498554416509 -2.35798390576557 0.569601955068737 36.0722962534869 34.7511723634428 1.03801667109896 0.300910734279938 53.074407904242 142.040043570998 0.37365806549977 0.709179383221196 GATA2 other 1 1 1 1.03801667109896 0.37365806549977 2.64712492115301e-07 114.092543101614 20.8164864675142 5.48087417536407 1.74950271208853e-07 21.9026265188647 35.9705983499464 0.608903591365955 0.543509405404744 ARID3B other 0.00253885751187786 1 0.00200493010805346 5.48087417536407 0.608903591365955 1.0700368534678e-19 1205.00968394501 113.940008036523 10.57582586407 8.6103122163683e-20 422.240200546946 232.402268469133 1.81685059843995 0.0712769585911832 PACS2 other 1.50939398550168e-15 1 1.23230788440663e-15 10.57582586407 1.81685059843995 1.38069597209064e-17 220.536604381838 29.5660422124243 7.45911822750372 5.94240197315007e-12 -16.6798507266562 46.6277591110312 -0.357723618819804 0.721039959940909 ELMOD2 other 1.91695828765064e-13 1 7.96103592342914e-08 7.45911822750372 -0.357723618819804 0.84615852058666 28.2398859774148 55.8976968149661 0.505206611122014 0.614140695269038 57.8503453568686 102.817326634119 0.562651716891379 0.574495565493007 EGR3 other 1 1 1 0.505206611122014 0.562651716891379 3.14194474310145e-06 7.42682633544592 1.94715255558861 3.8141984890346 0.000197297605604593 -8.9100696016297 6.05057138374922 -1.47259969951939 0.142899837953808 CATSPERE other 0.0272783642596068 1 1 3.8141984890346 -1.47259969951939 0.0406412032763066 18.9687148147157 8.55479909327306 2.21731856095037 0.028125855251638 -3.2108019208721 16.0691758341463 -0.199811238237202 0.841902489074198 GPC5 other 1 1 1 2.21731856095037 -0.199811238237202 0.00218395091205466 260.754981223567 333.589501410089 0.781664231402221 0.435855390193122 -1890.90531117836 745.483116291081 -2.53648308037608 0.0123989862550336 VWA1 other 1 1 1 0.781664231402221 -2.53648308037608 1.51206978483022e-20 309.568663535303 28.6773369906916 10.7948887874696 6.20372798744254e-20 -127.771738548945 116.103232399502 -1.10050113083236 0.273086854446423 GEMIN4 essential 2.14230047114746e-16 1 8.88187735962148e-16 10.7948887874696 -1.10050113083236 0.122664786787322 12.6962873035931 64.1604251286803 0.197883465985915 0.843397205382614 -186.986805051098 108.275203233247 -1.72695870769497 0.0861801941020295 FJX1 other 1 1 1 0.197883465985915 -1.72695870769497 7.58959639705744e-10 105.965846558582 15.8783441813413 6.67360811356529 5.4795316354812e-10 18.3946325858702 24.0344839186063 0.765343356161268 0.445364667380221 KLHL28 other 8.62102254741754e-06 1 6.97544377196757e-06 6.67360811356529 0.765343356161268 0.00700775272549768 30.3899128686326 9.72321669914133 3.12549990491484 0.00215291695256054 16.8872989276139 15.3830700821438 1.09778469690626 0.274156513931736 MKRN3 other 1 1 1 3.12549990491484 1.09778469690626 0.647953699490095 15.2933171118153 22.7722585680121 0.671576649551032 0.502859413257875 62.4362267994567 70.762393855319 0.882336272103993 0.378970152197523 ZBTB18 other 1 1 1 0.671576649551032 0.882336272103993 0.000850025763967543 19.141984293153 6.08213752491563 3.14724621315078 0.00201700340633516 -7.04259061792197 9.20631489428945 -0.764973900935149 0.445583918774414 C14orf28 other 1 1 1 3.14724621315078 -0.764973900935149 0.0122745260008721 8.10399575671854 2.79078487671599 2.90384107507948 0.00423953396696408 -3.26524045261665 17.8580378518277 -0.182844301244578 0.855165452149955 ALOX12B other 1 1 1 2.90384107507948 -0.182844301244578 5.58765501472829e-06 643.199718045113 124.966810702091 5.14696433742267 1.1813318771799e-06 413.99765037594 521.677190564016 0.793589710005038 0.429158523256146 SHARPIN other 0.0472715614246014 1 0.0128552534874717 5.14696433742267 0.793589710005038 0.000242782364469679 1.56269767529167 38.6201413176809 0.040463282162467 0.967778313217205 -197.425796097643 62.0338972978327 -3.18254703794889 0.00177942358769019 DNHD1 other 1 1 1 0.040463282162467 -3.18254703794889 4.97279662249847e-11 164.123900999758 23.8297035209638 6.88736646913681 1.33654827113106e-10 -62.1692569429849 80.3662290650324 -0.773574393949447 0.440360722752536 GCC1 other 5.95790763341542e-07 1 1.73457234627389e-06 6.88736646913681 -0.773574393949447 0.000450564947414877 16.9724039829304 14.2280157845895 1.19288622109299 0.235037675355694 -90.3524608819344 30.1439616375317 -2.99736517609677 0.00325035810519222 LSMEM2 other 1 1 1 1.19288622109299 -2.99736517609677 0.145948311349119 111.218497513984 140.220251342116 0.793170005398344 0.428899106511763 -345.005399316346 306.131980159117 -1.12698254895494 0.261502817793684 CIITA other 1 1 1 0.793170005398344 -1.12698254895494 9.81074302380981e-09 198.424796030145 32.8016611418377 6.049230103687 1.15112057144906e-08 109.547552062445 57.7594986188706 1.89661535646805 0.059840485281947 ZFPM1 other 0.000104641385091955 1 0.000139757548579631 6.049230103687 1.89661535646805 0.394153823693275 20.1708220544237 15.4383298813056 1.30654171853451 0.19336811380029 65.9022937740423 98.7818380181426 0.667149904235822 0.50570138839529 ALOX15B other 1 1 1 1.30654171853451 0.667149904235822 0.00372653684244899 33.0095859708634 9.7696921615487 3.37877442042459 0.00092100167818051 9.47286246479094 30.5697987281777 0.309876507497556 0.757071090887924 PLD6 other 1 1 1 3.37877442042459 0.309876507497556 0.000190678371324522 1284.33333333333 302.879256623306 4.24041364751059 3.80915600413618e-05 496.500000000012 1243.92881896413 0.399138594130706 0.690336952386985 CDC42EP4 other 1 1 0.364421954915709 4.24041364751059 0.399138594130706 2.55846021666027e-16 633.101251584416 67.2262830789281 9.41746624368796 1.04963055555062e-16 292.75297198835 137.5198201989 2.12880566281231 0.0349720532876382 ZBTB42 other 3.50176449854291e-12 1 1.48123863999303e-12 9.41746624368796 2.12880566281231 0.0565624427442804 13.3056187998047 10.0439194928332 1.32474367295545 0.187231402364714 -16.21148696265 17.1143634772175 -0.947244516819488 0.34500786986641 LACC1 other 1 1 1 1.32474367295545 -0.947244516819488 5.82117081560533e-06 1196.3359962406 232.447399330527 5.14669555213857 1.18269311334946e-06 832.549968671679 970.357693817915 0.857982550121259 0.392784773750401 MAF1 other 0.0491656087086026 1 0.0128688837663555 5.14669555213857 0.857982550121259 0.226359003989913 24.1308740601504 13.9447036955642 1.73046875623656 0.0863766465706845 37.2989505012532 58.2125270404125 0.64073752502377 0.523038031360131 WDR97 other 1 1 1 1.73046875623656 0.64073752502377 0.660024414501412 5.26470630839429 9.63764870083688 0.546264599573662 0.585690282136852 28.5991888172666 32.7521807241072 0.873199530076366 0.383940828438102 PCED1B other 1 1 1 0.546264599573662 0.873199530076366 0.401838740572101 32.0407379315408 38.5163314254875 0.831874084205703 0.40680238493941 -43.8193204092007 77.2290178037703 -0.567394506046164 0.571294378473584 APOBEC3B other 1 1 1 0.831874084205703 -0.567394506046164 0.807760675289302 11.6254676258993 42.4240553175833 0.274030088327764 0.784480345749423 -99.9750599520381 184.010550164441 -0.543311564813514 0.587811301323674 PIPOX other 1 1 1 0.274030088327764 -0.543311564813514 0.735245200928734 0.544938605430159 1.41255101080847 0.385783310663071 0.70026440988655 2.89222907186746 3.68357772134853 0.785168466815636 0.433730564908562 ATP8B5P other 1 1 1 0.385783310663071 0.785168466815636 0.77698685483946 -17.7665580310965 46.7273117759599 -0.380217850243142 0.704325165064006 11.1956507462198 73.7273571483366 0.151852055725999 0.879509039773055 CDH5 other 1 1 1 -0.380217850243142 0.151852055725999 0.852794265304803 15.5162425816793 28.7060441606494 0.540521797250946 0.589618126685278 24.1992946118292 63.054345058271 0.383784727118578 0.701667351345152 LRRC3B other 1 1 1 0.540521797250946 0.383784727118578 0.0585691654392527 -70.5663908945867 63.5085155612441 -1.11113273977466 0.268254273684781 -259.24765209954 108.407633153939 -2.39141511125335 0.0179983011118754 FAM216B other 1 1 1 -1.11113273977466 -2.39141511125335 0.00198233589730471 509.231069303507 234.710144386894 2.16961678684026 0.031549491244335 -631.272755104559 521.501691666529 -1.21049033050543 0.227921642181227 MYADM other 1 1 1 2.16961678684026 -1.21049033050543 0.000506401129382026 563.294172932331 150.554744825321 3.74145745845398 0.000293694693560811 -208.715225563908 628.494684831076 -0.332087495091555 0.740460931737162 MROH1 other 1 1 1 3.74145745845398 -0.332087495091555 0.672351503679574 4.94145302936219 5.67136682917398 0.871298432671106 0.384930128920077 5.08197799441448 8.19591212185844 0.620062528594088 0.536121314610638 AKAP5 other 1 1 1 0.871298432671106 0.620062528594088 1.85375684141847e-06 3.34013321798589 1.17380036778125 2.84557179369392 0.00502509815850434 -10.9396619848357 3.70339961712998 -2.95395126527382 0.0036202726361114 NKPD1 other 0.0165077046728314 1 1 2.84557179369392 -2.95395126527382 0.421595544207276 -3.89704251971831 6.29364748791209 -0.619202541483802 0.536722250087525 6.6320589032369 9.51096990970182 0.697306264892265 0.486690507234071 GIPC3 other 1 1 1 -0.619202541483802 0.697306264892265 7.70550945930051e-16 1294.58641144668 137.994262753427 9.38145097930553 9.69258954284116e-17 1113.65717129412 965.463428657439 1.15349493128161 0.250541980180069 CITED4 other 1.04779517627568e-11 1 1.36849671755374e-12 9.38145097930553 1.15349493128161 0.0650724843825215 19.0412696330395 15.4617227330604 1.23151022442831 0.220009365305318 -43.9328153510394 37.6017809932527 -1.1683705981619 0.244462836099128 ABCA13 other 1 1 1 1.23151022442831 -1.1683705981619 2.38658364782456e-08 193.858822212271 32.4473117409761 5.97457267831085 2.78702514042913e-08 -63.7018958053442 136.531492894298 -0.466572908967326 0.641711748760232 TIGD5 other 0.000248347894392624 1 0.000332631450510216 5.97457267831085 -0.466572908967326 0.4405955732764 -43.392001047458 44.3475820232884 -0.978452467254505 0.329436566241342 -154.892605350093 141.756180892815 -1.09266914764874 0.276302605824213 C1orf194 other 1 1 1 -0.978452467254505 -1.09266914764874 0.0577260626061508 14.3137146760759 6.24784963474013 2.29098258006832 0.0233296186148713 7.72980370897279 12.4336828935352 0.621682551755591 0.535075860218324 ZNF154 other 1 1 1 2.29098258006832 0.621682551755591 2.04311280399865e-06 234.709975363111 54.1937453909625 4.33094213492489 2.90068835667899e-05 -333.781515117154 181.110018355971 -1.84297654070746 0.0675588365050496 R3HDM2 other 0.018112195007448 1 0.281395777481429 4.33094213492489 -1.84297654070746 0.423616656072364 -34.541318495637 46.0217011005933 -0.750544149164266 0.45410277634196 -311.098075323749 246.849266520921 -1.26027546975669 0.209527047740073 B3GNT3 other 1 1 1 -0.750544149164266 -1.26027546975669 0.155476894113706 131.205191024795 91.5471403305389 1.43319813760504 0.153815196392721 -104.373939837525 195.274816465559 -0.534497697791634 0.593763091159802 SEPHS2 essential 1 1 1 1.43319813760504 -0.534497697791634 0.452761084818554 0.125243291064582 1.99834252309441 0.0626735855426049 0.950115189304596 6.04629902683574 5.11877866962587 1.18119954330389 0.239511990175963 GPBAR1 other 1 1 1 0.0626735855426049 1.18119954330389 4.06567693186541e-12 52.0047229230071 11.0942091513699 4.68755566200821 6.18971344036337e-06 -57.1380578757605 22.2132421982183 -2.57225205424283 0.0110816572933162 ZNF784 other 5.06540408454915e-08 1 0.0640016369733572 4.68755566200821 -2.57225205424283 1.2931410176417e-11 304.280195208847 64.490895928352 4.71818837106706 5.51635047486809e-06 -671.510891325908 154.067993936026 -4.35853595656437 2.45610202299656e-05 C14orf119 other 1.58345117610226e-07 0.355299718646683 0.0572872996815051 4.71818837106706 -4.35853595656437 3.99605335688951e-11 102.665656537239 23.2351460989595 4.41855007495891 1.87193382169974e-05 -149.231519253415 50.4844214707265 -2.95599147035779 0.00361073503566665 BBS10 other 4.80845100434515e-07 1 0.185115535627887 4.41855007495891 -2.95599147035779 3.36858173538267e-17 225.382864303421 34.5841701258314 6.51693718494288 1.02630302570319e-09 -172.559616080635 68.8705948563044 -2.50556302643637 0.0132934443749208 FIZ1 other 4.65639053281947e-13 1 1.29468126692458e-05 6.51693718494288 -2.50556302643637 7.7688422171294e-09 2185.23456231622 333.037560894478 6.56152584245174 1.75937433375029e-09 1191.12768604388 1402.0138573639 0.849583390198058 0.397385443912232 PUF60 essential 8.33208327787128e-05 1 2.20361635302224e-05 6.56152584245174 0.849583390198058 0.044143915823689 162.972540338466 66.524746299645 2.44980325974329 0.0154442836716552 114.918221338413 132.087746232003 0.870014248986934 0.385682731766022 SSC5D other 1 1 1 2.44980325974329 0.870014248986934 0.00211522804199607 91.8006053674059 123.884159904582 0.74101971905135 0.459802640205082 -741.673436366679 264.833423031003 -2.80052807488673 0.00575186622578031 DCTPP1 other 1 1 1 0.74101971905135 -2.80052807488673 6.712501500877e-06 98.60469787424 40.2242351241432 2.45137533553885 0.0153420931149868 -247.267589131284 85.9893781814856 -2.87555968377176 0.00460089872018089 ZNF771 other 0.0563514500998624 1 1 2.45137533553885 -2.87555968377176 1.6778853071912e-12 464.875955633539 92.6033922662308 5.02007479701219 1.44606889294331e-06 -197.665998245394 173.161717560578 -1.14151095883098 0.255476402025446 TSHZ1 other 2.11514221824522e-08 1 0.0156431170313413 5.02007479701219 -1.14151095883098 3.25317662280288e-08 50.3984504094299 10.6066934038607 4.75157039903555 4.56884468378006e-06 -26.391354239342 19.2359161262755 -1.37198322482247 0.172051094336859 PSTK other 0.000335500105109661 1 0.0477992530817069 4.75157039903555 -1.37198322482247 9.73440040752038e-08 135.973433825102 28.2187631089011 4.81854691151263 3.40009262347332e-06 -34.1593792317012 41.4505867339586 -0.824098810734468 0.41114160676898 SOCS4 other 0.000969448936584955 1 0.0358777773628905 4.81854691151263 -0.824098810734468 4.91510234666205e-16 220.399970150538 54.5869628304582 4.03759357037465 8.53738970326729e-05 -345.664876542116 102.223489853319 -3.38146229441114 0.000916717540628071 ZADH2 other 6.70321658037771e-12 1 0.786464339464983 4.03759357037465 -3.38146229441114 1.89276644268764e-10 151.984319031412 23.0741625273178 6.58677509320115 6.61369098429047e-10 16.6570774981867 49.3268021544477 0.337688168919435 0.736055084318413 ZNF48 other 2.21377963136746e-06 1 8.39145112086774e-06 6.58677509320115 0.337688168919435 0.481216202015509 -5.52015700353558 5.50532105383543 -1.00269483824015 0.317601685109463 15.8465979117627 22.4733578287582 0.70512818033291 0.481809597732036 C3orf80 other 1 1 1 -1.00269483824015 0.70512818033291 0.390667444255442 3.62232951036317 2.76039866520561 1.31224868205527 0.191414422938938 2.19625317935196 5.47991415578638 0.400782405876355 0.689143125539676 TMEM150B other 1 1 1 1.31224868205527 0.400782405876355 0.828985494172634 0.118621576752223 3.05671018205967 0.0388069426563343 0.969098058856568 -3.67967292571092 7.0112795999942 -0.524821877837244 0.600514066746828 ANKRD18A other 1 1 1 0.0388069426563343 -0.524821877837244 0.000866148510108863 24.4497326605919 10.6080425570931 2.30482980521638 0.0225030848190528 -26.7458832241383 21.1232889185421 -1.26617987034494 0.207348337757108 TMEM86B other 1 1 1 2.30482980521638 -1.26617987034494 4.09729412450629e-05 31.3946604921051 16.3108338103135 1.92477348841934 0.0560893006894114 -101.778999051498 34.8684929033883 -2.91893886361827 0.00403570479564969 SEPT1 other 0.314958999350798 1 1 1.92477348841934 -2.91893886361827 2.25119910966948e-08 49.0279519495997 18.2858266875739 2.68119964097203 0.00815176218453028 -132.782800638636 42.1576614152724 -3.14967187887071 0.00197076598998167 TRNAU1AP other 0.00023484509112072 1 1 2.68119964097203 -3.14967187887071 6.29148420973358e-12 401.453625092109 52.9622832664668 7.57999089790545 8.02732912611166e-12 -0.712779931437402 182.939941730408 -0.00389625100289909 0.996897719158052 EXOC3 essential 7.78634085796628e-08 1 1.07180898491843e-07 7.57999089790545 -0.00389625100289909 6.64024205938699e-07 26.6978853429042 4.91652728529697 5.43023231514347 2.7556836080365e-07 14.0932356840301 13.2984478823153 1.05976545599519 0.291262681950302 TDRD6 other 0.00615152024381611 1 0.00311915827593651 5.43023231514347 1.05976545599519 0.949537159942547 -61.1320792200255 247.596641424612 -0.246901891997751 0.805304666047355 15.0041973572941 442.428418746818 0.033913276637594 0.972989111150357 ACTA2-AS1 other 1 1 1 -0.246901891997751 0.033913276637594 0.0767505147666259 336.250987949615 156.750689782379 2.14513242918701 0.03381601578815 -77.5964843292993 677.213021594574 -0.114582091387714 0.908954527768052 LYNX1 other 1 1 1 2.14513242918701 -0.114582091387714 0.353311656722612 23.0462042133232 29.4986092283744 0.781264094008718 0.435831213156365 -57.142949326248 72.1579776779838 -0.791914507100758 0.429613051202682 FAR2P1 other 1 1 1 0.781264094008718 -0.791914507100758 1.53045728886774e-05 84.8498282724333 31.7909629220094 2.66899208056672 0.00852699781098201 -139.288940414047 68.3545974392229 -2.03774062948575 0.0435007105403704 FAHD1 other 0.12393643125251 1 1 2.66899208056672 -2.03774062948575 3.1472490660755e-10 71.9335270904439 26.196262398392 2.74594619631155 0.00691714297824886 -138.141176052332 49.1209565051204 -2.81226559661826 0.00570777266457408 TDRP other 3.64545859323525e-06 1 1 2.74594619631155 -2.81226559661826 4.29513889392137e-08 188.847099084865 76.3986183235218 2.47186537176841 0.014551287920094 -568.855251321917 176.135710947449 -3.22964178168071 0.00152104186519327 RCC1 essential 0.000439092049125581 1 1 2.47186537176841 -3.22964178168071 0.102436804658471 18.8284522680355 14.5695700596496 1.29231351309266 0.198171895159118 -29.8515092339452 31.1461054743313 -0.958434731383897 0.339336185555796 MYLPF other 1 1 1 1.29231351309266 -0.958434731383897 6.90661580999916e-11 315.076812611171 44.0867681816672 7.14674324307109 3.92384462732223e-11 -28.908957391602 167.362524847686 -0.172732560158923 0.863100874829333 PRKRA other 8.234758030262e-07 1 5.1716272188107e-07 7.14674324307109 -0.172732560158923 0.0074460765869556 47.9176069831808 27.1010481561004 1.7681089936883 0.0794629494187134 -55.4128959107992 44.9342696506052 -1.23319898913841 0.219797244067319 HERC2P3 other 1 1 1 1.7681089936883 -1.23319898913841 0.0248719409225676 -24.2225143686293 43.5592204041347 -0.556082366578123 0.578977620685843 -242.616428347235 94.7608793490599 -2.56030157184945 0.0114396427909203 ZNRF2 other 1 1 1 -0.556082366578123 -2.56030157184945 0.122918387009828 26.2179932536197 16.0877524501804 1.62968651679655 0.105224865948722 -27.8411214013157 44.9434807411371 -0.619469630349135 0.536528403087969 SLC9A4 other 1 1 1 1.62968651679655 -0.619469630349135 7.05013384368179e-07 26.1617948968618 7.98497988520981 3.27637580469301 0.00129755692899643 -51.3853541772205 22.0173154602147 -2.33386101362238 0.0208870186247755 ZNF816 other 0.00651150361802451 1 1 3.27637580469301 -2.33386101362238 0.00237242617104498 37.7890547120963 22.0286479454357 1.71545048092369 0.08824809933854 -74.2577901447946 44.4180798605741 -1.6717919905112 0.0965699933485265 FGD6 other 1 1 1 1.71545048092369 -1.6717919905112 8.30178250958761e-08 411.062378573411 83.4232939117433 4.9274292502558 2.11897595328311e-06 -172.841891016745 137.148425268559 -1.26025428785122 0.209471644739188 OAZ2 other 0.000831672571810487 1 0.0226942324596621 4.9274292502558 -1.26025428785122 0.300830144119863 3.90227382680213 4.89131345844442 0.79779671860228 0.426258083659901 -7.0565070149976 10.2396437912622 -0.689135985474334 0.491809438560305 ALX1 other 1 1 1 0.79779671860228 -0.689135985474334 2.03128991517242e-13 158.134826159541 18.868076007811 8.38107849968786 2.79275404578101e-14 4.80910212673316 74.336249670468 0.064693903015714 0.948500017218102 CCDC43 other 2.62970792418222e-09 1 3.86433377314718e-10 8.38107849968786 0.064693903015714 9.29680217077804e-13 70.7907381868331 8.72818550637913 8.11059046981696 1.35355668229072e-13 55.0903680046455 34.3872145047412 1.60205962588362 0.111152513919368 MEIOC other 1.18162355590589e-08 1 1.85829796911693e-09 8.11059046981696 1.60205962588362 9.56462241694431e-10 566.27486027437 82.5011260187845 6.86384401766149 1.46681444674168e-10 431.391449517313 325.037078464611 1.32720688838053 0.186367087152402 FZD2 other 1.08061104066637e-05 1 1.90172493020059e-06 6.86384401766149 1.32720688838053 8.80058644682351e-09 32.4054773082945 11.9107254609124 2.72069719133733 0.0072592291721968 -46.7619848721959 17.7992796310529 -2.62718412438526 0.00947425242314008 TIGD2 other 9.41398732216711e-05 1 1 2.72069719133733 -2.62718412438526 0.00148628483747364 81.2603075941487 52.9133280027252 1.53572475331666 0.126698601667008 -226.452072838788 115.110266995218 -1.96726216305446 0.0509854682222072 MTURN other 1 1 1 1.53572475331666 -1.96726216305446 6.59842443628084e-09 527.051259367193 86.3016729601215 6.10708044571435 7.8403344117337e-09 37.2593903228795 141.880498713522 0.262611075240944 0.793199083398287 ZNF609 other 7.11244169986711e-05 1 9.58637688522679e-05 6.10708044571435 0.262611075240944 2.41051380968555e-15 726.466050596408 79.0228476181687 9.19311404856766 3.74215639119125e-16 285.890709427476 295.708742589016 0.966798299314454 0.335254634357866 PAK2 other 3.25130102650387e-11 1 5.26446561112786e-12 9.19311404856766 0.966798299314454 2.2512290554359e-11 70.9009773519028 14.2848173965379 4.96338002676089 1.81709222625203e-06 -83.3302827624141 32.1404003947626 -2.59269585129353 0.010439921066402 CCDC66 other 2.73366744201581e-07 1 0.0195337414322093 4.96338002676089 -2.59269585129353 0.358493247434542 6.558004317407 15.0744459794986 0.435041150190592 0.664137684485696 34.2553408515241 24.6213257754733 1.39128742147784 0.166131998058467 ATP5EP2 other 1 1 1 0.435041150190592 1.39128742147784 0.00908011741239759 278.207525873778 96.1683353916769 2.89292234019323 0.00437773303312226 -280.811661852199 428.11579900039 -0.655924547769243 0.512864314044561 MCFD2 other 1 1 1 2.89292234019323 -0.655924547769243 3.36618799395379e-48 67.8370022451236 3.05215880411148 22.2259084795137 3.08214260441206e-48 -15.6461584731111 19.7067944910279 -0.793947411398361 0.428541576987215 HARBI1 other 4.90958518918161e-44 1 4.49530498853498e-44 22.2259084795137 -0.793947411398361 2.75417509653332e-07 71.153525998007 16.3763533416958 4.34489440435089 2.55558839075452e-05 -48.7754118060848 43.591472008844 -1.11892096225126 0.26496248304934 C11orf71 other 0.00263657181991135 1 0.249399871053734 4.34489440435089 -1.11892096225126 0.0250442476881809 15.417535779537 9.2069951126624 1.67454588504487 0.0960142157201766 -18.6934112362974 17.6952079180019 -1.0564109403473 0.292403352145451 TPRXL other 1 1 1 1.67454588504487 -1.0564109403473 0.357518437095904 68.2537149544525 55.4422083498914 1.23107857687971 0.220194945047159 2.92556124648105 94.340630472415 0.0310106179260322 0.975301753188487 SERTM1 other 1 1 1 1.23107857687971 0.0310106179260322 0.0869359390300254 475.682171592946 258.833897005265 1.83778932008766 0.0680204373830768 -84.01973985909 385.223956160849 -0.21810621721565 0.827635097390089 GAS1 other 1 1 1 1.83778932008766 -0.21810621721565 0.547096451216575 -8.78819961298018 48.8693426189397 -0.179830526502197 0.857547511550569 64.8682457576659 73.0824038501917 0.887604161059567 0.37628698644791 ARHGAP45 other 1 1 1 -0.179830526502197 0.887604161059567 2.39936087184435e-19 22.11637313124 2.70257999819996 8.18342959171254 1.16619987728889e-13 -32.6910356064075 10.5488410238119 -3.09901680503234 0.00232437340580854 ZNF571 other 3.37758029929529e-15 1 1.60247525138267e-09 8.18342959171254 -3.09901680503234 0.0974356479266733 -0.591093117408883 2.64990734831268 -0.223061805457183 0.823784931728334 -11.5052423959306 5.74243745843798 -2.0035468351553 0.0468840772378631 GLIPR1L2 other 1 1 1 -0.223061805457183 -2.0035468351553 2.93963227157771e-12 109.688369308238 17.4370262781601 6.29054332765576 3.08212828026704e-09 -137.131336547023 51.8898298620684 -2.64274014602747 0.00906801535214325 MIGA1 other 3.67983167756098e-08 1 3.82399655732731e-05 6.29054332765576 -2.64274014602747 0.00547098599065304 11.4488641832708 3.86232250782286 2.96424344680743 0.00355210439055986 -2.05958225045721 14.1492179793416 -0.145561560608104 0.884471070525354 PRR26 other 1 1 1 2.96424344680743 -0.145561560608104 7.55445239024979e-06 820.66158706191 162.817763860332 5.04036886150758 1.5239452741812e-06 511.578121274737 334.527052729132 1.52925784955563 0.128630185035033 NRIP1 other 0.0631023408157565 1 0.0164616568517054 5.04036886150758 1.52925784955563 0.0961348418184441 8.8160824514991 4.07417841014529 2.16389209405896 0.0320449414498053 5.19659391534393 13.0688773212729 0.397631241582255 0.691463577974218 BHLHA15 other 1 1 1 2.16389209405896 0.397631241582255 0.493137658015571 25.2597506360797 37.0285207389501 0.682170125405769 0.496169599363415 -59.5279125209442 103.535214848974 -0.574953291088224 0.566172942150968 RNF182 other 1 1 1 0.682170125405769 -0.574953291088224 0.0161805954820391 199.945677817434 70.1132210643627 2.85175427376083 0.00494897009260426 83.7254063461191 322.432911269745 0.259667680995737 0.795469206212563 TSPYL5 other 1 1 1 2.85175427376083 0.259667680995737 0.313132642732113 134.234719162996 133.910377245841 1.00242208202102 0.317764935906555 -245.368570793724 379.890659893903 -0.645892612527646 0.51934239863814 HIST1H2AC other 1 1 1 1.00242208202102 -0.645892612527646 0.000691215919891608 35.1041176003601 9.80942585226597 3.57861083095409 0.000461412885980609 -4.69172775146206 38.066059701905 -0.123252256424829 0.902067020812925 SKIDA1 other 1 1 1 3.57861083095409 -0.123252256424829 0.803154761183112 -6.77767070484582 10.6770813068819 -0.634786840152398 0.526540971818275 -13.1022152021022 30.2898367313667 -0.432561433668414 0.665958834988369 HIST1H2BC other 1 1 1 -0.634786840152398 -0.432561433668414 0.000590634308639139 43.5969739656252 11.0318296726662 3.95192595056524 0.000118400340306271 35.9805837334547 40.4470518806431 0.889572467225333 0.375101225819071 MB21D2 other 1 1 1 3.95192595056524 0.889572467225333 0.683235028619816 5.58254974852395 7.00480241753896 0.79696034459817 0.426677632784024 -9.62614804286032 27.8777194812026 -0.345298977893477 0.73033180665313 SSTR2 other 1 1 1 0.79696034459817 -0.345298977893477 5.80778550694932e-14 74.4676129727787 9.43211481312572 7.89511307359721 4.81603826416725e-13 -93.6555116341746 48.2213167546902 -1.94220145647651 0.0539140238106905 ZNF594 other 7.62968782047932e-10 1 6.57148421145622e-09 7.89511307359721 -1.94220145647651 3.07291189669686e-06 96.912361444221 76.0285407982384 1.27468395982245 0.204292534161454 -445.078783950218 131.841691380861 -3.3758576614774 0.000926190189246578 PCGF5 other 0.0267097502060891 1 1 1.27468395982245 -3.3758576614774 0.261353301803898 0.0435379265629033 2.22992667770267 0.0195243758452889 0.984447741280259 -21.3291718867783 14.1342307762646 -1.50904369855034 0.133310298063432 SLC47A2 other 1 1 1 0.0195243758452889 -1.50904369855034 0.053968956037294 22.4032202095912 12.0756401153377 1.85524079846799 0.0654489950786648 58.445455717161 26.5324815913764 2.20278889164129 0.0290762511308168 PRF1 other 1 1 1 1.85524079846799 2.20278889164129 0.193355558380907 5.65574392549807 3.42882553882895 1.64946972701028 0.101050826065516 11.4435318935466 7.07978259376536 1.61636769801718 0.108022455318168 OR2A4 other 1 1 1 1.64946972701028 1.61636769801718 0.000380013798812859 32.5679697042768 11.2820845164325 2.88669790204472 0.00444925197277718 -76.7263858198306 39.8637172513077 -1.92471728956269 0.0560963939809163 YOD1 other 1 1 1 2.88669790204472 -1.92471728956269 0.0246031737650087 54.461193014289 24.28095320833 2.24295943190587 0.026384966729947 -75.6151961896123 97.0816492485968 -0.778882484742143 0.437292521365528 TMEM64 other 1 1 1 2.24295943190587 -0.778882484742143 0.308652997699329 -18.538959349742 13.256736719855 -1.39845572417348 0.163973848248197 -4.31625690853585 21.6524331271036 -0.199342812107936 0.842255856481487 SHISA2 other 1 1 1 -1.39845572417348 -0.199342812107936 0.425463871946962 10.582109669255 8.50269566229641 1.24455938322941 0.215172314474986 5.1685137067849 34.146743172799 0.151361835025663 0.879887113510331 S1PR5 other 1 1 1 1.24455938322941 0.151361835025663 0.00126954455462513 23.6412031405507 15.1308435054441 1.56245110406731 0.120234395427814 -63.9210660179143 30.8236295718737 -2.07376830391972 0.0397658803970388 SMG1P3 other 1 1 1 1.56245110406731 -2.07376830391972 0.000754065803108487 117.844444444444 39.4356495432403 2.98827192678113 0.00326933588689769 -22.5123456790126 83.8814736540479 -0.26838281086787 0.788766188623453 GPR157 other 1 1 1 2.98827192678113 -0.26838281086787 0.0799822683813324 41.611851363895 20.8456929567227 1.99618460515007 0.0476539836695954 9.80570111087813 36.8733346668136 0.265929328049176 0.790644769958744 PIPSL other 1 1 1 1.99618460515007 0.265929328049176 0.166917387469123 5.19145160097612 2.73686756528701 1.89685890059927 0.0597817008484529 1.42510291108975 11.5707722540243 0.123164027413477 0.902143188736351 CHST13 other 1 1 1 1.89685890059927 0.123164027413477 0.000185186017056988 11.70635397681 4.76805309578686 2.45516434939744 0.0152021014165807 -7.75704812502423 7.12567252001103 -1.08860575661316 0.278039541287207 WDFY3-AS2 other 1 1 1 2.45516434939744 -1.08860575661316 0.807841827750251 9.05492147754919 13.9785952867091 0.647770487078817 0.518091739724871 6.82368060163678 38.7120626572169 0.176267554174478 0.860313842779807 SLC36A4 other 1 1 1 0.647770487078817 0.176267554174478 4.57633793136964e-07 441.301873935264 116.538518550213 3.78674690072638 0.000221846991054343 -257.710494037478 190.147948914887 -1.3553156660808 0.177395850186927 ZDHHC20 other 0.00429992712031492 1 1 3.78674690072638 -1.3553156660808 9.5301202123552e-11 120.429178994083 16.8471540788206 7.14833962048702 3.12011268821964e-11 -30.1206413778533 91.1300862013179 -0.330523569475322 0.741445051743428 ZFP3 other 1.12931924516409e-06 1 4.11886075971875e-07 7.14833962048702 -0.330523569475322 0.131982817882605 5.58725406330187 28.9952241940217 0.192695666911031 0.847449565673093 -61.0829769033363 43.9007004310866 -1.39138957473405 0.166101092162303 ARSJ other 1 1 1 0.192695666911031 -1.39138957473405 0.621341151713517 -9.09262822274751 10.794227806945 -0.842360230427724 0.401002865599639 -22.5809268319499 30.7626023731328 -0.734038250667357 0.464135720436007 HOXC9 other 1 1 1 -0.842360230427724 -0.734038250667357 0.00154241951954565 165.017491470368 348.126567851996 0.474015793992847 0.636147193552584 -2398.5757810914 763.523038137843 -3.14145829435781 0.00200961788281501 PPA1 essential 1 1 1 0.474015793992847 -3.14145829435781 0.389108240060621 -53.1531526579076 41.8633867450861 -1.26968114122173 0.206275049766666 -108.239894453301 119.306979940073 -0.907238574873567 0.365817655221053 HOXC10 other 1 1 1 -1.26968114122173 -0.907238574873567 6.81319746946284e-11 173.002289000083 25.2005431694684 6.86502222736545 1.67367148470737e-10 39.4456583639732 65.1275441214809 0.60566783065543 0.545656826891753 PSMG4 essential 8.12473798233444e-07 1 2.16589826835981e-06 6.86502222736545 0.60566783065543 2.75174860808966e-07 27.0192608016658 5.10945066415962 5.28809505710528 4.39184426024641e-07 60.9615478049627 22.3123513027535 2.73218841787596 0.00706300773333101 MAP6D1 other 0.00263477933043571 1 0.00491227780508561 5.28809505710528 2.73218841787596 3.15461576278344e-10 44.6114953261937 8.13365193194851 5.48480506658545 1.71741621162846e-07 -66.6012923130091 36.1918337936824 -1.84022983451684 0.0677107684752929 ZNF443 other 3.65367597645578e-06 1 0.00196987639473784 5.48480506658545 -1.84022983451684 0.190026017081722 1.81034410443287 2.52355640833946 0.717378101179085 0.474234640371295 -13.0140804760765 9.97388896776193 -1.30481505440267 0.193914957663001 LINC01559 other 1 1 1 0.717378101179085 -1.30481505440267 0.000614394441743102 7.3697975708502 3.6703519216205 2.00792668611362 0.0464111836768452 -15.9562794560366 7.95377482680061 -2.00612662584703 0.0466050435655959 CAPS2 other 1 1 1 2.00792668611362 -2.00612662584703 7.04404385013693e-23 68.3177301905882 5.87703640938182 11.6245204949776 6.28128308232937e-23 39.0356397085791 26.3180616158532 1.48322624509189 0.140018966672576 ZNF792 other 1.0083548771471e-18 1 9.05195704994485e-19 11.6245204949776 1.48322624509189 4.34687982569443e-10 505.607412246838 102.657825673572 4.92517164599365 2.11722738299059e-06 -1923.60453168617 392.049469436057 -4.90653522488674 2.29911746835816e-06 CUEDC1 other 4.99804242358346e-06 0.0335073379838518 0.0226776224992122 4.92517164599365 -4.90653522488674 5.96422444390485e-16 330.200957982035 35.7368137593132 9.23979849479398 1.73522390542668e-16 290.739943485952 155.664531303961 1.86773403710209 0.063675026777461 KCTD2 other 8.12506295993158e-12 1 2.44527752752727e-12 9.23979849479398 1.86773403710209 0.0532326041121895 34.9723469870509 55.2048795805354 0.633501010287173 0.527447519729395 -209.380950990299 115.707339092334 -1.80957364185182 0.0725225801071094 D2HGDH other 1 1 1 0.633501010287173 -1.80957364185182 0.206045926355031 -2.8009570526894 152.082100425446 -0.0184174011593329 0.985330509967177 -466.146507958287 292.860006957767 -1.5917042166345 0.11357053894313 OXTR other 1 1 1 -0.0184174011593329 -1.5917042166345 3.10725438894662e-12 163.006513479283 31.5779305634521 5.16203913843376 7.48641743396513e-07 -40.1756830106749 50.256126616453 -0.799418612526378 0.425287058511143 CMTR2 other 3.88624306425554e-08 1 0.00824029966956542 5.16203913843376 -0.799418612526378 4.5890796726393e-08 1533.08592700403 265.449213896793 5.7754396952183 6.98277387506832e-08 -711.530732198835 1116.95470337465 -0.637027383517961 0.525406978903519 FAM83H other 0.000468040235812482 1 0.000817892303986753 5.7754396952183 -0.637027383517961 4.19899457033606e-05 10.3104152718016 2.73604992520044 3.76835787126445 0.000241406775644135 -5.00503179721081 6.25557852129195 -0.80009095564468 0.425013642974606 GPR62 other 0.322314823218996 1 1 3.76835787126445 -0.80009095564468 1.45999622909442e-26 64.3959835239442 4.90928505067787 13.1171815975633 1.28609791654901e-26 122.879937917325 45.5991032850335 2.69478847312458 0.00785249280788138 ZNF572 other 2.10925655217271e-22 1 1.86136951462138e-22 13.1171815975633 2.69478847312458 1.78221240845347e-06 54.4407465320117 12.8855761072585 4.22493694335832 4.07759190781887e-05 -33.6368940882813 22.8613482163458 -1.47134341203163 0.143238741681682 ST20 other 0.0158955524709965 1 0.388879940248686 4.22493694335832 -1.47134341203163 1.85220606858322e-11 377.450560336819 67.3081808766569 5.60779619090438 9.94804805111515e-08 -245.297089963471 113.010568364865 -2.17056770453101 0.0315803654276511 PITPNB other 2.25617221214123e-07 1 0.0011561621445006 5.60779619090438 -2.17056770453101 6.15841621575686e-14 139.385601719197 23.7984702179459 5.85691434964964 3.21311952805151e-08 -87.4286011982287 36.5819667329871 -2.38993714680166 0.0181826371940673 LRRC57 other 8.0847688080456e-10 1 0.000382489748619252 5.85691434964964 -2.38993714680166 6.98219077990079e-07 213.131778476086 65.3807825954458 3.2598535841162 0.0013932042152248 -519.408704990342 199.322286894483 -2.60587369873649 0.0101338791812987 MRPL14 essential 0.00645014784247235 1 1 3.2598535841162 -2.60587369873649 0.00988070463360535 50.194863463416 16.419650477757 3.05699950991117 0.00262844902954654 23.7395507143899 25.2272538981674 0.941027937888807 0.348136189680696 GPR137C other 1 1 1 3.05699950991117 0.941027937888807 7.00683606381905e-09 48.2352941176471 11.6584844578406 4.13735544204527 5.71130752102969e-05 -21.8318014705881 17.5458214107678 -1.24427354864048 0.215253285145595 BBS12 other 7.54184182569459e-05 1 0.536406002375108 4.13735544204527 -1.24427354864048 3.98323062583382e-18 58.2259145608636 6.99203892428159 8.32745858417059 4.62413230884936e-14 -61.6264235172281 28.3047092079795 -2.17724983727636 0.0310148705160684 ZFP82 other 5.55979330753885e-14 1 6.37806569359592e-10 8.32745858417059 -2.17724983727636 0.0159102800894319 4.94084832415617 1.69689422759357 2.911700826022 0.00413619732145029 4.35516600927998 5.20348704787581 0.836970663943108 0.403923033162833 LSMEM1 other 1 1 1 2.911700826022 0.836970663943108 0.00929980040604485 -346.923159535211 231.005290761897 -1.50179746269445 0.135237720338242 -1117.03225910644 371.817082533858 -3.00425212175322 0.00311775151594112 NQO1 other 1 1 1 -1.50179746269445 -3.00425212175322 0.000782333468505885 58.6154446259348 19.6835368713846 2.97789188035349 0.0033693880142311 -47.5675428117676 34.4014073426867 -1.38272083865429 0.168739336771548 AEN other 1 1 1 2.97789188035349 -1.38272083865429 3.21797983340647e-15 116.248323879448 16.9693292746713 6.85049609196768 1.60233990720576e-10 -31.0580270009556 34.927705915923 -0.889208901257861 0.375259948207428 FKRP other 4.32882647189839e-11 1 2.07551088180362e-06 6.85049609196768 -0.889208901257861 1.11524290332584e-07 138.7425880494 60.7271073570149 2.28468955772471 0.0237056349301467 -655.493248160006 182.465251722225 -3.59242782926085 0.000441012578350158 TRAPPC5 other 0.00110531724148624 1 1 2.28468955772471 -3.59242782926085 0.153551255430392 42.6105946325203 21.8695800193322 1.94839565253898 0.0534733404285601 38.9337835467437 95.2339746295139 0.408822415510922 0.683327524711808 RPH3AL other 1 1 1 1.94839565253898 0.408822415510922 3.18016591567279e-12 100.048963810702 13.6118736936493 7.35012431516909 1.24272511593472e-11 17.1611073306527 45.8820023435214 0.374026992156235 0.708919531589064 SLC25A42 other 3.97584342777412e-08 1 1.65456421935548e-07 7.35012431516909 0.374026992156235 3.33624784776925e-11 192.418421640957 25.9626582579289 7.41135286415415 7.26643026089556e-12 -110.75354907221 114.316315947033 -0.968834134958707 0.334118088720043 METTL23 other 4.02384852919449e-07 1 9.71739718789563e-08 7.41135286415415 -0.968834134958707 7.82301243391184e-12 180.107720862854 23.525109425426 7.65597802780858 1.79228215565358e-12 148.969634894407 102.530345752556 1.45293214219648 0.148225758753296 SLC26A11 other 9.65203274096043e-08 1 2.42477852838373e-08 7.65597802780858 1.45293214219648 0.00990118205917901 -19.809160678762 167.448452310081 -0.11830005237719 0.905983085852047 -1056.25638921199 369.488347274444 -2.85870013764585 0.00483944845487767 HIGD1A other 1 1 1 -0.11830005237719 -2.85870013764585 0.00214716615366474 584.738244514107 177.484599580198 3.29458581700712 0.0013200823327448 -308.753396029259 746.818027326108 -0.413425204978933 0.680085623016088 MAPK15 other 1 1 1 3.29458581700712 -0.413425204978933 2.28907748879655e-09 674.099016937106 103.894122764523 6.48832675997424 2.17483596430174e-09 170.832938528958 163.216756481282 1.04666299105478 0.297412520147233 EHMT1 other 2.53355096460003e-05 1 2.71484773423786e-05 6.48832675997424 1.04666299105478 0.732875302128244 2.41778922345484 8.26643735352427 0.292482616156772 0.770324536554785 -24.3988930151147 34.9452791549654 -0.698202836123225 0.486138577564727 ADIPOQ other 1 1 1 0.292482616156772 -0.698202836123225 0.572597654149417 40.5258206110187 115.425109887419 0.351100559059859 0.725995903583069 -74.597594564821 162.819224192166 -0.458162080890263 0.647486060895405 F2R other 1 1 1 0.351100559059859 -0.458162080890263 0.00222608867046559 4619.43519991505 1796.37264619722 2.57153503739552 0.0111103682284734 -8702.25517037722 7788.96822828033 -1.11725390518104 0.265696205110365 MUC16 other 1 1 1 2.57153503739552 -1.11725390518104 0.0012322991221649 1464.59224740946 471.315753149386 3.10745447743447 0.00225264472674733 -621.45974830582 774.824118267988 -0.802065570306468 0.423767214886443 NPM1 essential 1 1 1 3.10745447743447 -0.802065570306468 3.49810767479317e-18 265.843460716829 28.2146268257732 9.4221859590214 6.91113906065432e-17 -100.420761136166 143.155225028766 -0.701481633771921 0.484075113413083 DHTKD1 other 4.88580698938361e-14 1 9.76682172051668e-13 9.4221859590214 -0.701481633771921 0.0579898449553558 140.027600816899 66.391857092492 2.10910805856542 0.0365321010956478 -55.1640046331576 210.043432643106 -0.262631418364264 0.793181197111357 HIST3H2A other 1 1 1 2.10910805856542 -0.262631418364264 7.347872841771e-05 122.639294827186 28.9838477746394 4.2312979208542 4.29867545201114e-05 -23.9286874109422 88.2086244404945 -0.271273784878988 0.786601057886874 ZNF746 other 0.548812622551876 1 0.409233903031461 4.2312979208542 -0.271273784878988 2.80922291037609e-05 1186.23240060214 263.513345716752 4.5016027456811 1.35699404709717e-05 -485.592269547521 1413.87878136623 -0.343446889469755 0.73174968680694 POLR2A essential 0.221254396421221 1 0.135957233578666 4.5016027456811 -0.343446889469755 0.062761935137781 203.766695933923 88.2195559523976 2.30976787101347 0.0222650936942476 137.113396374486 171.989901717594 0.797217714558761 0.426584721509259 TMEM132C other 1 1 1 2.30976787101347 0.797217714558761 3.04855834958858e-10 72.8003900156006 11.9792648272704 6.07720015087008 9.43316217959065e-09 -36.9789001560063 33.5070098917516 -1.10361683347667 0.271503504924433 TMEM136 other 3.53175484799838e-06 1 0.000114952514320492 6.07720015087008 -1.10361683347667 1.22892991354376e-06 137.620034330554 45.8636326660733 3.00063528182659 0.00313175353152316 -164.072917396483 81.5973978534246 -2.01076163839453 0.0460515027991147 FRAT2 other 0.0111218157175711 1 1 3.00063528182659 -2.01076163839453 1.41537455770875e-15 163.830597416577 18.1881612583577 9.00754040440973 9.74709114479182e-16 -9.10477215643802 96.9983000873139 -0.0938652754557789 0.925343132520721 TMEM102 other 1.91655868859342e-11 1 1.36683459123416e-11 9.00754040440973 -0.0938652754557789 0.755277544851466 21.9580411256485 34.1377386260657 0.643218971419581 0.521051215920513 63.0006745161832 131.763195633769 0.478135599346659 0.633240644014607 TMEM132E other 1 1 1 0.643218971419581 0.478135599346659 1.03576271914886e-14 136.85513552584 18.3415783806855 7.46146992834351 6.90196378600205e-12 -66.5436357065414 52.5120772721653 -1.26720631068643 0.207085389060875 ZNF322 other 1.381189585985e-10 1 9.23413734929214e-08 7.46146992834351 -1.26720631068643 0.209817391191774 -4.59366552283435 3.65824676488635 -1.25570138322177 0.211113850871814 -21.1334513944824 14.3977824276551 -1.46782683379695 0.14417756703625 NME9 other 1 1 1 -1.25570138322177 -1.46782683379695 2.22088906986541e-05 1943.6508180674 533.434450901035 3.64365446360718 0.000366161343895529 -4131.59285414627 1796.93693187255 -2.29924199389726 0.0228264361442961 LRRC75A other 0.177027067758972 1 1 3.64365446360718 -2.29924199389726 0.000681209334968296 7.2742701834089 10.6024786289339 0.686091473323758 0.493700622372967 -151.583605289 40.9229352034579 -3.70412348320977 0.000296344202931456 CCL13 other 1 1 1 0.686091473323758 -3.70412348320977 0.157280794991449 3.7057282177857 16.4465843576549 0.22531901683652 0.822050557307658 -66.7698225358272 40.5052821292099 -1.64842260134949 0.101446088678136 CFAP65 other 1 1 1 0.22531901683652 -1.64842260134949 0.487615553357696 34.9358494384299 43.0580577996851 0.811366123408507 0.418383798878487 -10.1353966406958 65.1453260059492 -0.155581332723244 0.876562894765041 DDX60L other 1 1 1 0.811366123408507 -0.155581332723244 1.44048766954391e-12 92.9110046010098 14.5622631739904 6.38025858281134 2.02178163610393e-09 -136.755497566215 63.9547816884354 -2.1383154465672 0.0340894593822113 SYNE4 other 1.8207764143035e-08 1 2.5270248669663e-05 6.38025858281134 -2.1383154465672 5.25639379834655e-07 213.957117112197 37.676956706274 5.6787260919237 8.16037055492207e-08 32.0416268465179 182.01882181773 0.176034689855337 0.860534439867887 OGFOD3 other 0.00491210000455485 1 0.000951988828937209 5.6787260919237 0.176034689855337 0.0712957402937891 55.5390593254776 24.005001675889 2.31364530089835 0.022244496876696 81.5847470540432 59.7451865837682 1.36554510445212 0.174421949867128 WASHC1 other 1 1 1 2.31364530089835 1.36554510445212 0.0963490596748078 89.1498382873863 43.3121969396266 2.05830792678684 0.0413508677392169 -120.111735715386 192.590967384935 -0.623662352114972 0.533829210427734 AATK other 1 1 1 2.05830792678684 -0.623662352114972 9.42081803364455e-05 349.177127046515 78.373283317926 4.45530813900009 1.9049483641006e-05 197.584808499321 240.027859854737 0.823174479074626 0.412055372949607 ZNF467 other 0.693372207276239 1 0.188181399641364 4.45530813900009 0.823174479074626 0.640587467266348 46.7295133127922 66.3070737923846 0.704744013573995 0.482077106156212 -173.53710989966 303.215266817726 -0.572323127792834 0.567971434777005 SOX2 og 1 1 1 0.704744013573995 -0.572323127792834 1.2465626261579e-11 63.2770292965107 9.85320187066616 6.42197634099957 1.56431360616193e-09 -52.6369596317722 32.0648655435281 -1.64157743185661 0.102705083241886 ZNF678 other 1.52716387330604e-07 1 1.96180569348767e-05 6.42197634099957 -1.64157743185661 0.0960221668242565 66.7682311829085 30.767066687443 2.17012014376264 0.0315304067974577 32.0042687647787 131.128241342363 0.244068466389468 0.807502652478176 TMEM45A other 1 1 1 2.17012014376264 0.244068466389468 0.0631761787738928 93.3004752214804 45.4685765201607 2.05197704353272 0.0418876915791931 -190.477144700598 184.855301178059 -1.03041213038908 0.304453390217997 RAP2B other 1 1 1 2.05197704353272 -1.03041213038908 1.31109123866359e-12 136.368652998659 19.3957764427707 7.030842688924 6.38485656139505e-11 10.7841522101195 38.8587415198043 0.277521911115505 0.781754016366815 ZBTB2 other 1.65931707165264e-08 1 8.36671603805208e-07 7.030842688924 0.277521911115505 0.00131705145199108 80.0298053527981 21.9729135197862 3.64220271839385 0.000373186955984483 -21.0180454176808 85.0218946454009 -0.247207445862508 0.805090280335156 RNF135 other 1 1 1 3.64220271839385 -0.247207445862508 7.38232457704477e-08 79.9503838199727 14.1849344256679 5.63628857355175 7.92842583128998e-08 -94.9646149532061 57.0256490133742 -1.66529652176224 0.0978606162649114 ACBD4 other 0.000743030968679557 1 0.000925960852836357 5.63628857355175 -1.66529652176224 1.91811868618627e-06 199.854224273864 38.3010660645947 5.2179807198267 5.60974343134775e-07 210.149683493682 166.13007597912 1.26497073004466 0.207744335678758 SGSH other 0.0170463207641374 1 0.00622793715748227 5.2179807198267 1.26497073004466 0.422236483284659 -2.68385395117915 14.526909854723 -0.18475050633749 0.85366780749385 -25.9107709281478 23.0094026168862 -1.12609489953174 0.261877138971818 MAB21L2 other 1 1 1 -0.18475050633749 -1.12609489953174 2.09613723901542e-13 614.951933754246 83.3468061960739 7.37823033443618 1.4325641769447e-11 -205.905887454128 187.463454082153 -1.09837881981996 0.273979847725409 SETD2 other 2.71261120100986e-09 1 1.90445081683028e-07 7.37823033443618 -1.09837881981996 0.196952459549979 24.2406164263612 31.9135634598031 0.759570972288746 0.448770219174873 -109.652705621388 97.3060370300348 -1.12688491863606 0.261691818198894 C6orf223 other 1 1 1 0.759570972288746 -1.12688491863606 0.0340055846736211 1.05471608907381 2.91265730735212 0.362114721292992 0.717804631837246 -14.2209824594582 6.35836850211997 -2.23657726895141 0.0268729442510209 TMIE other 1 1 1 0.362114721292992 -2.23657726895141 0.00163642309487199 216.61167379889 77.1055947954684 2.80928607545896 0.0056759185097472 -97.5469231775457 115.895205787955 -0.841682125799235 0.401401334140057 MEX3D other 1 1 1 2.80928607545896 -0.841682125799235 2.10824479741427e-10 367.924333313536 51.8397832877458 7.09733548212013 4.12717224762886e-11 -176.349572370374 197.975745154253 -0.890763523748683 0.374419062687436 MRPS23 essential 2.45990002962297e-06 1 5.43589856735197e-07 7.09733548212013 -0.890763523748683 0.0154986634452395 22.4472674007475 11.6192106329154 1.93190984395772 0.0551713928308047 -15.6025861198101 16.3386725735198 -0.954948209507379 0.341071929346885 GPR135 other 1 1 1 1.93190984395772 -0.954948209507379 0.410308568496533 -5.88953514444943 4.7244263527921 -1.24661381184803 0.214431943475748 -11.8717804808776 19.4644448427123 -0.609921350277941 0.542812827854422 P2RY13 other 1 1 1 -1.24661381184803 -0.609921350277941 0.567504821812464 7.24899037617371 17.4188061817093 0.416158851562718 0.67785850127243 -18.9452963653543 28.5123258792193 -0.664459870640094 0.507364598592421 TNFSF15 other 1 1 1 0.416158851562718 -0.664459870640094 7.19532632625763e-07 116.034515437179 22.9022598181244 5.06650943438129 1.49982158802949e-06 -86.551212030525 98.4760857144317 -0.878905892761748 0.381223568534687 ZFP41 other 0.00663840806860529 1 0.0162055722586587 5.06650943438129 -0.878905892761748 0.456562495959571 -162.016434991718 129.248824583765 -1.25352346927315 0.211965530376268 -163.838483285913 212.19038613328 -0.772129625057582 0.44125246718143 PHLDA2 other 1 1 1 -1.25352346927315 -0.772129625057582 0.0845471308598815 -24.9948797172433 21.2356882272325 -1.17702235264455 0.241050904079863 -147.753383775433 68.1913269478591 -2.16674744998597 0.0318328157627669 ATG9B other 1 1 1 -1.17702235264455 -2.16674744998597 1.69174821268815e-24 187.243483451615 18.6523038303031 10.0386249953431 1.96188063518789e-18 -232.561242347761 76.1556211893752 -3.05376331668878 0.00267754291584054 HKR1 other 2.43307227948809e-20 1 2.79411040063459e-14 10.0386249953431 -3.05376331668878 4.13570143047354e-05 235.160753544228 51.1344120430785 4.59887469413192 8.92362471021727e-06 -8.79690179753316 209.415189785216 -0.0420069900686554 0.966548619525457 C3orf58 other 0.317745940903282 1 0.0909942011700855 4.59887469413192 -0.0420069900686554 1.86340679031882e-11 187.049584099234 37.825234886258 4.9451003982315 1.94875909297108e-06 -67.880387204274 54.5831762244292 -1.2436137267859 0.215507349585704 C5orf30 other 2.26925678925026e-07 1 0.0209218776221375 4.9451003982315 -1.2436137267859 0.000464538832422177 26.9534361075247 12.8749944336684 2.09347167071707 0.0379786090406196 -109.167587298197 41.5519615409789 -2.62725472515985 0.00949574885575667 AMIGO1 other 1 1 1 2.09347167071707 -2.62725472515985 0.00352526849273348 17.5126109331679 5.73790803833784 3.05208985856124 0.00269162085029224 4.03253775842204 12.6837768458635 0.317928784732377 0.750984096730266 GPR3 other 1 1 1 3.05208985856124 0.317928784732377 5.5082313710706e-13 389.804913485291 47.6321245799403 8.18365581890194 9.67399418129959e-14 -84.2338590890591 199.970414616889 -0.421231606937645 0.674173289450446 SIAH2 other 7.05053615497037e-09 1 1.33027093987051e-09 8.18365581890194 -0.421231606937645 5.73707831824083e-12 1012.77948295736 131.029016707 7.72942901053803 1.36966718928477e-12 -140.115214885559 539.07457327446 -0.259918055556706 0.795278718534547 COPG1 essential 7.10938745196404e-08 1 1.85562510804301e-08 7.72942901053803 -0.259918055556706 0.596347201578928 6.87400484596748 46.4586231868985 0.147959719303649 0.882593700206405 197.730605745933 195.990267760332 1.0088797163527 0.314823925685831 ADGRB1 other 1 1 1 0.147959719303649 1.0088797163527 6.80082711759616e-11 7.18174408770831 1.13132446650767 6.34808518715938 2.29251781095685e-09 -1.45194578701289 2.54437663198009 -0.570648923891018 0.569063999528808 LINC00471 other 8.11066642044517e-07 1 2.85945746560647e-05 6.34808518715938 -0.570648923891018 0.903028393418821 -2.50392311086384 6.29374209856488 -0.397843297620155 0.691307582969679 -6.85497918545092 25.775307534969 -0.265951402370307 0.790639417689785 SLC9A9 other 1 1 1 -0.397843297620155 -0.265951402370307 0.00695521317369014 63.1285520152445 38.0531171858502 1.6589587577524 0.0992562191338281 -262.678551635654 135.014907809556 -1.94555220528812 0.053616537571282 LSM10 essential 1 1 1 1.6589587577524 -1.94555220528812 0.0132089644374374 21.0337470591116 11.5720512542928 1.81763341666059 0.0710638661601847 -16.9568537565259 20.1988999264669 -0.839493923840233 0.402493518380556 RELL1 other 1 1 1 1.81763341666059 -0.839493923840233 8.71417675029356e-13 320.518422915807 43.2358146795219 7.41326202111825 8.01794686817233e-12 3.41381497433482 64.7493637328582 0.0527235292754301 0.958021419480922 RFX7 other 1.10835614086984e-08 1 1.07063644530705e-07 7.41326202111825 0.0527235292754301 4.38679956947662e-42 371.273878253824 19.373399775009 19.1641055553272 4.79619715827807e-42 -96.791290008103 123.144017731937 -0.786000747667669 0.433115240833096 SLC35C1 other 6.39244433264133e-38 1 6.98997773847446e-38 19.1641055553272 -0.786000747667669 1.53419256093606e-12 297.37537083837 48.7679040745144 6.09776812191885 1.11012977832431e-08 -394.973277661795 132.96908501416 -2.9704143457085 0.00353419853018733 RNF41 other 1.93707152743786e-08 1 0.000134880768066403 6.09776812191885 -2.9704143457085 0.944807925885257 1.91019878596914 6.06221644556111 0.315099073601675 0.753139436739862 -1.23671284926563 32.1339891978465 -0.0384861288665805 0.969353027850266 SLC2A4 other 1 1 1 0.315099073601675 -0.0384861288665805 1.32512946413428e-08 48.9875662405173 8.52381559283541 5.74714055072862 5.38649682448097e-08 -8.6380397130819 26.8777349888302 -0.321382725020233 0.748396280532602 IBA57 other 0.000140317958957179 1 0.000634690920828592 5.74714055072862 -0.321382725020233 1.23722832910524e-06 1142.67151661183 209.454140150926 5.45547352651259 2.05713581094862e-07 1054.68237492859 1110.25350834881 0.949947347157798 0.343719658248594 CLDN7 other 0.0111944419217442 1 0.00234657481954909 5.45547352651259 0.949947347157798 9.50937402455994e-07 45.3647533525851 14.5166801231055 3.12500881523043 0.00214804224804091 -54.0296194469717 28.7695600126445 -1.87801340803353 0.0623874356874858 ZNF329 other 0.00869442067065516 1 1 3.12500881523043 -1.87801340803353 1.47697530418224e-05 44.5767131737406 13.2213385653742 3.37157338141873 0.000946463435969161 -68.9139007196359 42.7525719775172 -1.61192409092666 0.109039379674528 ZNF101 other 0.119797466922221 1 1 3.37157338141873 -1.61192409092666 1.87939176153318e-08 238.70983386556 71.5175657494765 3.33777906677853 0.00105456717915723 -343.451211572276 116.64256379592 -2.94447584479697 0.00372690666638927 C5orf24 other 0.000197129401867215 1 1 3.33777906677853 -2.94447584479697 0.000228724781409307 89.0504117959614 32.7671119512746 2.71767655106075 0.00733786366157584 -148.451153787764 70.7958317205063 -2.09689116124564 0.037659043883203 ADO other 1 1 1 2.71767655106075 -2.09689116124564 1.1551418608058e-05 250.506277589863 69.001583025588 3.63044247110922 0.000384585177465903 -537.650270404556 258.240881415305 -2.0819719459519 0.0389992243621312 COA4 other 0.0948718010279802 1 1 3.63044247110922 -2.0819719459519 6.48024915839046e-08 161.424510129525 49.583146233725 3.25563265728646 0.00141472287798256 -483.560677515775 134.99380237424 -3.58209539261077 0.000467377119809986 PRKAG1 other 0.000654699572472188 1 1 3.25563265728646 -3.58209539261077 0.000292097613919964 70.2731404079399 21.1983983950494 3.31502121520423 0.00115081714029658 19.2608976502417 33.1826386247175 0.580451056592418 0.562487310468282 GINS3 essential 1 1 1 3.31502121520423 0.580451056592418 1.82192264093897e-07 45.9262950751429 18.9128140852065 2.42831631867339 0.0163288802167889 -97.8796813578247 34.4162872531387 -2.84399303846751 0.00506482021569313 CCDC149 other 0.00177455265227455 1 1 2.42831631867339 -2.84399303846751 0.00127704431956437 151.173036831133 53.0374914540679 2.85030518387268 0.00497041484418651 -128.406011118832 92.6693711377411 -1.38563593927894 0.167874612321943 MRPS11 essential 1 1 1 2.85030518387268 -1.38563593927894 0.000195261971517207 177.065889701401 50.5453931835231 3.50310638713404 0.000603168505822336 -301.466321983546 186.900214278904 -1.61298007681082 0.108809558654263 SNRPE essential 1 1 1 3.50310638713404 -1.61298007681082 0.00392813514931007 65.434112646121 19.6359143258733 3.33236902342263 0.00108136944868535 23.3274631850614 42.4248828630359 0.549853331601918 0.583227005215746 RTKN2 other 1 1 1 3.33236902342263 0.549853331601918 0.919852096707843 31.1063639490884 107.978285823412 0.288079808934546 0.773670495383348 -24.2589611283109 196.32758558832 -0.123563691040237 0.901820826368031 CHST15 other 1 1 1 0.288079808934546 -0.123563691040237 0.686627111727356 2.78953401445303 3.25527259730688 0.856927931860712 0.392824927470322 2.10740094692262 13.7599870760132 0.153154282433615 0.878478413650752 USH1G other 1 1 1 0.856927931860712 0.153154282433615 0.00114269031470813 1161.74492944516 315.50786308709 3.682142556062 0.000318883368742461 276.396608152335 578.30849440881 0.477939734284705 0.633366449747737 IDH2 other 1 1 1 3.682142556062 0.477939734284705 0.00392093328938829 3.60175631645135 2.51237946538577 1.43360362798472 0.153699549803338 -6.02658768720707 3.73582836657806 -1.61318644644462 0.108738122575257 OGFRP1 other 1 1 1 1.43360362798472 -1.61318644644462 0.0118001364383572 254.445296219113 186.042644533141 1.36767189510568 0.173622024206712 -498.736900863353 278.220310576866 -1.79259702438425 0.0752122579316741 TMEM259 other 1 1 1 1.36767189510568 -1.79259702438425 0.0037425247980032 70.4162119414791 38.1238494342639 1.84703834965292 0.0667117750445773 -128.999841834717 72.6177288587701 -1.77642352442062 0.0776902764644951 WRB essential 1 1 1 1.84703834965292 -1.77642352442062 7.41010734867239e-11 2419.25566674038 456.482349152951 5.29977921650105 4.06833860172028e-07 -183.763876603271 906.726060485609 -0.202667469935576 0.839669588021254 TNRC18 other 8.82025077712475e-07 1 0.00455857340322757 5.29977921650105 -0.202667469935576 0.808071888110725 -2.34753492302411 14.0771031025858 -0.166762643273736 0.867774164043367 -32.9241965723943 50.494702896709 -0.652032682314092 0.515345808647686 FAM181B other 1 1 1 -0.166762643273736 -0.652032682314092 0.00583212740256062 84.9989517787386 160.660822096468 0.529058364507195 0.597507441944068 -566.719838203967 223.643682561944 -2.53403016670055 0.0122492222338218 TMEM30B other 1 1 1 0.529058364507195 -2.53403016670055 2.59110013983866e-12 193.927614201367 31.9296592320269 6.0735885964874 9.38720886886397e-09 -86.9215001553765 69.7095441845804 -1.24690960430356 0.214323751125418 DEXI other 3.2489804653437e-08 1 0.000114401914484845 6.0735885964874 -1.24690960430356 0.00130091007989455 55.8616378789708 166.467893965538 0.335570040253739 0.7376608987689 -724.031682570358 241.513942424952 -2.99788772151464 0.00317980821600157 NOP10 essential 1 1 1 0.335570040253739 -2.99788772151464 0.437051771887792 12.3494652690475 23.3576672187258 0.528711414260881 0.597776828814174 49.7213821555677 38.5758038470273 1.28892666379003 0.199381769490543 KCNIP1 other 1 1 1 0.528711414260881 1.28892666379003 6.85725603931732e-09 50.3801151420999 9.23207225675114 5.45707548002112 1.89442878628505e-07 -20.6306101312864 29.1304532797924 -0.708214524955495 0.479882614286009 ZNF708 other 7.38732193115655e-05 1 0.00216627931711695 5.45707548002112 -0.708214524955495 5.55789628810499e-15 624.183085155377 112.849236439744 5.53112369075407 1.32318769876528e-07 -236.357950101245 178.780194617838 -1.32205891489539 0.188096240920579 IST1 other 7.44924839494711e-11 1 0.00152735556068476 5.53112369075407 -1.32205891489539 9.96756697747339e-09 65.5673334771754 12.6375264489248 5.1883043522931 6.51198142810554e-07 -9.11985636346826 19.4363762087498 -0.469215879828602 0.639570449679735 ERCC6L2 other 0.000106274199113821 1 0.00719769307248506 5.1883043522931 -0.469215879828602 0.082228160162017 -146.407378581801 93.7911778454021 -1.56099306933886 0.121180935772325 -320.096204405889 146.845028827872 -2.17982322562037 0.0312396536672537 MRPL41 essential 1 1 1 -1.56099306933886 -2.17982322562037 4.0771176088258e-07 419.338801220432 75.6022481259731 5.5466445987387 1.20899273156483e-07 -16.633916210098 272.853500621778 -0.0609628103439856 0.951466362364921 CREB3L2 og 0.00384920673449244 1 0.00139904638896682 5.5466445987387 -0.0609628103439856 0.00262894514515749 28.6936535753625 15.060281939671 1.90525341360172 0.0586109005194715 -100.188192116914 45.275664067731 -2.21284865014978 0.0283792938144407 TP53TG1 other 1 1 1 1.90525341360172 -2.21284865014978 0.424312179541544 -6.77100843226007 34.3076325956694 -0.197361575835308 0.843801514194179 -55.6664030152553 50.8310913847974 -1.09512507992115 0.27514973693082 UNC5C other 1 1 1 -0.197361575835308 -1.09512507992115 8.75918980592454e-14 318.08912718008 37.1261055481612 8.5678021565565 9.94473595014305e-15 18.7488114624924 172.311347985279 0.108807758059522 0.91349570231151 TSEN54 essential 1.14473851573628e-09 1 1.3834122180244e-10 8.5678021565565 0.108807758059522 1.39710362458521e-09 464.842759477937 68.2475389566294 6.81112852689589 2.07998460476124e-10 193.313130468041 134.831757780297 1.43373589168093 0.153688132032764 RGMA other 1.56489576989789e-05 1 2.68401213398391e-06 6.81112852689589 1.43373589168093 1.0679956511121e-08 416.052397850133 99.4862185850039 4.18201037055847 4.87999160870066e-05 -568.304246473952 214.013060273248 -2.655465258748 0.00876985587804113 MRPS16 essential 0.00011365609719135 1 0.462344715412384 4.18201037055847 -2.655465258748 8.51735121063872e-05 23.2857142857142 8.87068529254225 2.62501864487189 0.00956160170241875 -22.5507389162562 13.04617089238 -1.72853315369551 0.0859503740419892 RAD51B other 0.630283989587265 1 1 2.62501864487189 -1.72853315369551 6.21313425967513e-08 181.041765794343 147.448093665636 1.22783388576651 0.221555116465617 -1508.81331688548 327.92854802634 -4.60104289780923 9.2785961693945e-06 ARL6IP4 other 0.000628334267680946 0.134780887956624 1 1.22783388576651 -4.60104289780923 2.52920461995991e-10 499.065033854385 70.1214136827579 7.11715591063589 4.41479663672225e-11 448.853932959961 378.384022581553 1.18623912790403 0.237428711733268 EXT1 ts 2.94095913208938e-06 1 5.80545757728975e-07 7.11715591063589 1.18623912790403 0.000152668677272067 431.688417641661 204.700624780629 2.10887689328885 0.036858865559667 -1371.54300011471 491.484905998243 -2.79061062379728 0.00604734280505015 SHMT2 other 1 1 1 2.10887689328885 -2.79061062379728 0.000260400175343853 68.2715322188561 21.2289456352904 3.21596434376673 0.00158845972864411 -13.0033658700777 36.699006494468 -0.35432473824701 0.723586598374311 MOB2 other 1 1 1 3.21596434376673 -0.35432473824701 0.000381099692329812 64.9340771734078 16.2681445599042 3.99148636369076 0.000101593723506961 25.3456066945607 26.4774480437218 0.957252626941534 0.339949900385521 HHIPL1 other 1 1 0.92907460147116 3.99148636369076 0.957252626941534 3.67859315720774e-12 166.127535496957 26.9021160580659 6.17525904424714 6.55828273937915e-09 -429.967951318459 135.108782982875 -3.18238342338528 0.00179466551705763 CYB5D1 other 4.58830924498521e-08 1 8.04963623431397e-05 6.17525904424714 -3.18238342338528 0.0866053196560187 -46.1333086625053 353.763780357474 -0.130407099946433 0.896414538682333 -1407.32348020926 677.51500449145 -2.07718422600193 0.0394450966217772 BACE2 other 1 1 1 -0.130407099946433 -2.07718422600193 1.93027298484487e-06 137.425984810307 65.5715916868589 2.09581590556157 0.0377236035169974 -426.0760019801 126.337835456504 -3.37251307528369 0.000940719138105355 UBE2E2 other 0.017146614924377 1 1 2.09581590556157 -3.37251307528369 0.00645419103630434 44.3726208060328 13.7440007184148 3.22850832993485 0.00152086795141065 26.9272183016107 27.4904723794781 0.979510934912569 0.328863847078724 SYNM other 1 1 1 3.22850832993485 0.979510934912569 0.0778548564029896 35.6141495384781 22.8407517401743 1.5592371890211 0.121033676139635 -16.8382560105184 32.0874136010188 -0.524762021018228 0.600518207252935 GABRG3 other 1 1 1 1.5592371890211 -0.524762021018228 7.28305782856536e-08 -0.259639589243624 2.86498210546037 -0.0906252045165579 0.927908169976507 -22.1352539257602 4.46938882775282 -4.95263553448529 1.90579224746572e-06 PRR34 other 0.000733250947225472 0.0277864509680502 1 -0.0906252045165579 -4.95263553448529 2.6356894529006e-05 168.392846497764 36.9221912513402 4.56074899107327 1.0209378843391e-05 -3.88152011922526 112.19229816962 -0.0345970283392976 0.972445018190154 FIGN other 0.208351251251793 1 0.103614985881576 4.56074899107327 -0.0345970283392976 0.00129416065645071 376.460417713689 119.420047918325 3.15240551545551 0.00195827407534114 4.45431437739178 206.309765449113 0.0215904194728506 0.982803561970891 B4GALNT4 other 1 1 1 3.15240551545551 0.0215904194728506 0.0133511380448832 435.065815408346 152.0393960809 2.86153343556329 0.00514442492432368 3.10719284714418 558.72419035262 0.00556122842145635 0.995573995518631 C8orf33 other 1 1 1 2.86153343556329 0.00556122842145635 0.007431846084577 3.87793047172496 17.7293762970246 0.218729097220174 0.827145156635575 -85.9014519596922 34.399869617667 -2.49714469602452 0.0135511233180453 SPACA6 other 1 1 1 0.218729097220174 -2.49714469602452 4.07491539564024e-11 26.9206914082359 6.65270330278516 4.04657929010085 8.44676273198116e-05 -36.7830028808678 13.2436642464084 -2.77740376050708 0.00620936576471262 ZSCAN22 other 4.90049325479695e-07 1 0.778538121006703 4.04657929010085 -2.77740376050708 0.000214760459162751 25.8753221212532 11.3968299673672 2.27039643438945 0.0245435962471448 -28.7691577376916 19.9574606573453 -1.44152396097061 0.151428357193239 KCNJ14 other 1 1 1 2.27039643438945 -1.44152396097061 0.000288728486218517 316.471307349346 75.9836166266375 4.16499400001449 6.3640214079258e-05 223.230320245458 292.134891207793 0.764134401483306 0.44648478923536 FBXL6 other 1 1 0.595099641855141 4.16499400001449 0.764134401483306 0.0554113471522531 562.720119519482 232.901139359988 2.41613296124629 0.0169300457679077 920.508226111348 967.897556894259 0.951038898233228 0.343167178551749 C1S other 1 1 1 2.41613296124629 0.951038898233228 0.549844186689643 -3.89738060575546 7.14638930253897 -0.545363601220381 0.586287397813251 -22.9426562824962 21.1563667555456 -1.08443271699676 0.279856858183578 KIAA2012 other 1 1 1 -0.545363601220381 -1.08443271699676 2.91788474662284e-07 30.7918620458905 7.55216630146095 4.077222457341 7.28430247609406e-05 -34.5044641479462 20.564185861834 -1.67789108597703 0.0953966691105609 KBTBD3 other 0.00278570456760082 1 0.676128955831051 4.077222457341 -1.67789108597703 4.01288770112978e-05 66.766481223922 24.561985025514 2.71828523446162 0.0074108189023911 -92.5874972549594 44.327176703691 -2.08872985243046 0.0385823847399856 YBEY other 0.308631193093892 1 1 2.71828523446162 -2.08872985243046 0.674017885116722 -53.6215301674697 302.561965715443 -0.177224953046148 0.859605422372806 545.979983941272 726.449366911606 0.751573349512886 0.453655804896342 NXPH4 other 1 1 1 -0.177224953046148 0.751573349512886 4.6158102444475e-06 46.3132117533304 9.8351890455365 4.70892949173648 5.43846579734735e-06 -19.6741020269303 27.9985969604116 -0.70268171132819 0.483294702997307 CACNB4 other 0.0393682455748927 1 0.0565165365660337 4.70892949173648 -0.70268171132819 0.00433007677146383 58.4539341971065 31.2682262106243 1.86943556706281 0.0635929496765958 -80.2005061761037 47.3688745312536 -1.69310558821042 0.0925976362666162 TRAPPC6B other 1 1 1 1.86943556706281 -1.69310558821042 0.000139415408355018 8.15596456760766 5.99717754777635 1.35996716832767 0.175827919789964 -24.1710267810981 8.69259616688585 -2.78064531206187 0.00610246835112978 PGBD4 other 1 1 1 1.35996716832767 -2.78064531206187 5.23295839774734e-06 617.259659549104 121.965970528624 5.06091704820436 1.28029090662528e-06 637.894270888116 516.227281258367 1.23568492802854 0.218630484525536 NPLOC4 essential 0.0444173508800794 1 0.0138949972096042 5.06091704820436 1.23568492802854 0.367225477634672 5.13127177579115 55.1223652811557 0.0930887444618662 0.925953273427409 -335.637138191316 250.783583760618 -1.33835370385206 0.182741075612536 TSHZ2 other 1 1 1 0.0930887444618662 -1.33835370385206 3.93874002082848e-07 373.449388820217 103.251481081476 3.61689135021247 0.000405131668681455 -721.035613239941 339.204723645811 -2.12566501282815 0.0351472398715262 CAPN12 other 0.00372210931968292 1 1 3.61689135021247 -2.12566501282815 7.62554005768989e-12 1019.92812223206 132.126460033465 7.71933284198892 1.28061809848482e-12 742.533757750223 584.585424330448 1.27018862743744 0.205896647346476 EXOC7 essential 9.41220409320663e-08 1 1.73562170887648e-08 7.71933284198892 1.27018862743744 0.00827807494844634 768.300731461012 244.614028519561 3.14086945916748 0.00202015506991317 238.230942438387 984.644242652033 0.241946209726203 0.809143729546263 KPNA2 other 1 1 1 3.14086945916748 0.241946209726203 0.866260680624058 -2.72789240129922 5.3578570101596 -0.509138709026122 0.611413241257215 1.55215035204971 21.3171820917082 0.0728121730804867 0.942053893601732 NCF1B other 1 1 1 -0.509138709026122 0.0728121730804867 6.77539656350734e-10 88.0555246113991 12.8923150779415 6.83007854516837 1.84841222098816e-10 2.69950129533688 57.1205757020267 0.0472597004172193 0.962367478544458 CEP97 other 7.71243390824041e-06 1 2.3894424780714e-06 6.83007854516837 0.0472597004172193 2.97318493821822e-05 126.934648560023 34.0210720998838 3.7310596264383 0.000271751655924494 -90.4186567341505 62.4724977790152 -1.44733538674874 0.149932240530549 FES other 0.233157162855073 1 1 3.7310596264383 -1.44733538674874 1.5866795744682e-06 322.930164820789 96.9344955616816 3.33142668097242 0.0010802248325202 -385.348412836835 159.911471044574 -2.40976091533435 0.0171348332493741 GLRX5 essential 0.0142214090259585 1 1 3.33142668097242 -2.40976091533435 5.9889400693538e-05 657.621193829645 147.333293824633 4.46349346273623 1.53194612611744e-05 680.273222669356 648.72399424778 1.04863274474402 0.295958758169206 MXRA7 other 0.451566081229277 1 0.152719709312647 4.46349346273623 1.04863274474402 1.66344773711996e-07 976.085819490354 196.892087266556 4.95746595529211 1.8868945281381e-06 -315.412025607768 338.504052272886 -0.931782126358409 0.352926767206567 LIMK2 other 0.00162602016303476 1 0.0202746817048439 4.95746595529211 -0.931782126358409 0.000267982209650688 55.9758253304799 31.8537990668889 1.75727313445212 0.0810263949582373 -246.144522648783 81.6605858170277 -3.0142390014236 0.00305218179074612 MFSD5 other 1 1 1 1.75727313445212 -3.0142390014236 2.2372207207717e-06 466.94283303449 118.742791518536 3.93238888073134 0.000127808927709357 -655.094399324967 353.745916614352 -1.85187833571275 0.0659960651978733 ADI1 other 0.0197591334058557 1 1 3.93238888073134 -1.85187833571275 1.08982682475414e-15 67.2396083613649 16.6383165887838 4.04125068798681 8.30335124381027e-05 -101.41386352715 26.3425417236875 -3.84981314980542 0.000171699330056131 RWDD4 other 1.47845907046146e-11 1 0.765984152241498 4.04125068798681 -3.84981314980542 0.00665556332250214 -1.63021739130435 1.84063380609305 -0.88568263057423 0.37715176876497 -33.3291545893721 10.4274271947155 -3.19629703156911 0.0016852494700962 SPNS3 other 1 1 1 -0.88568263057423 -3.19629703156911 0.000316831977204219 170.036025770259 51.7092743832759 3.28830809943164 0.00124242425458552 -66.862602445545 101.604047395279 -0.658070265502551 0.511450663100264 SATB1 other 1 1 1 3.28830809943164 -0.658070265502551 0.0738707398593728 5.28691185640907 2.63983648131562 2.00274217506617 0.046937330692372 12.8544226083714 10.8710662738765 1.18244358782551 0.238828845313806 NXPH3 other 1 1 1 2.00274217506617 1.18244358782551 0.753609045208449 -101.831082268875 176.668877348263 -0.576395139864606 0.565189609577465 50.6212616029887 284.917707327015 0.177669763237594 0.859215814144733 CSF1R other 1 1 1 -0.576395139864606 0.177669763237594 0.0661130548111515 253.482831218124 108.119008888913 2.34447978965999 0.0204393331929733 8.36561499229015 441.47513660318 0.0189492324678968 0.984908204365406 EPHB3 other 1 1 1 2.34447978965999 0.0189492324678968 1.18494354471246e-06 43.040220694067 14.810353527755 2.90609002772341 0.00418903482423328 -93.2979902979903 32.7563037133561 -2.84824536719474 0.00498516079497453 C2orf82 other 0.0107450680634526 1 1 2.90609002772341 -2.84824536719474 0.0613675424144787 -1.26000624519056 3.99249865448472 -0.315593405091122 0.752738421782359 14.9317657161338 8.05299091267818 1.85418881978696 0.0656247767872928 HS3ST4 other 1 1 1 -0.315593405091122 1.85418881978696 3.12613657860672e-13 696.780054685118 96.5831801213687 7.21430018984183 2.16998007034879e-11 -154.437377671554 216.161232346996 -0.714454557807302 0.476007069000524 TRAK1 other 4.02521345861401e-09 1 2.87392160516994e-07 7.21430018984183 -0.714454557807302 0.000154502706093571 63.9936800953682 14.8974217734272 4.29562115301823 3.2253432632169e-05 45.2175414606781 63.0541085068532 0.717122841499908 0.474484585691634 TSPAN10 other 1 1 0.311503652361488 4.29562115301823 0.717122841499908 5.11972979322548e-12 227.896597423412 29.6817798209102 7.67799636000478 1.87632458738355e-12 121.758244467731 96.0117312745026 1.26816007639335 0.206692581634573 PLCB1 other 6.35409664637214e-08 1 2.53735373951878e-08 7.67799636000478 1.26816007639335 0.00544355834562679 211.039546234201 74.5108606559263 2.832332687831 0.00523120090942672 491.509470631108 286.70992420435 1.71430923430746 0.0884579562850288 SKA2 other 1 1 1 2.832332687831 1.71430923430746 0.0162468667014444 27.9206496456415 9.90047458908415 2.82013244864298 0.00560434787110849 8.23180289625718 22.7175315491933 0.362354636921347 0.717713967895994 CCNYL2 other 1 1 1 2.82013244864298 0.362354636921347 0.342978161120542 23.4646946164707 68.9263563821664 0.340431379926268 0.734041972438454 -111.269050647953 108.595957735304 -1.02461503142838 0.307312019800309 NDN other 1 1 1 0.340431379926268 -1.02461503142838 0.104536918182164 -13.9945754132326 19.6321826194764 -0.712838489967441 0.477031462048039 90.1508922641874 54.3651510596308 1.6582478022604 0.0993162509814868 NTM other 1 1 1 -0.712838489967441 1.6582478022604 2.01945963283708e-06 724.507453608964 200.181815147377 3.61924709832195 0.000402529190770032 -733.175775929245 382.0356980995 -1.91912897034635 0.0568542809944745 TTC3 other 0.0179065485643664 1 1 3.61924709832195 -1.91912897034635 0.947173006482173 1.29121018799859 5.30351967878829 0.243462882425582 0.807990937962277 5.2832084448049 17.4263853061512 0.30317293873561 0.762192608056504 KCNB2 other 1 1 1 0.243462882425582 0.30317293873561 0.000385329061068265 19.3012078830261 8.98402767639022 2.14839140953997 0.0334284036571214 -33.1920745920746 19.0187462570268 -1.74522937229951 0.0831708469268261 BRICD5 other 1 1 1 2.14839140953997 -1.74522937229951 0.652852187536215 3.51683898507578 6.05083563406357 0.581215421763815 0.561934086972017 20.0812081447087 28.2204381412013 0.711583854376467 0.477785227895459 GALR2 other 1 1 1 0.581215421763815 0.711583854376467 0.0187079348379202 -1.2584646188524 11.1425826779362 -0.11294191438618 0.910225632411457 -41.5469150900416 16.1944917603988 -2.56549669509471 0.0112704139253697 IGIP other 1 1 1 -0.11294191438618 -2.56549669509471 0.447232619630567 93.3406929496239 91.080038839633 1.02482052202427 0.307076071812478 -164.370687269708 330.834156636039 -0.496837113014718 0.620021745773684 TSKU other 1 1 1 1.02482052202427 -0.496837113014718 0.0387161069195375 -954.140420410782 878.428828656397 -1.08618978485735 0.279172982584468 -3467.4623716303 1344.85528773051 -2.5783163462009 0.0109107901562795 ANXA2 other 1 1 1 -1.08618978485735 -2.5783163462009 0.00761517164236691 27.5878373442864 9.52311117499831 2.89693534364217 0.00431391702808601 6.6162043254238 14.3874103188984 0.459860682275334 0.646260609788331 RGS6 other 1 1 1 2.89693534364217 0.459860682275334 0.0570489666908808 135.556053811659 61.7314229261825 2.19590035975285 0.0296046569031486 -238.928251121079 251.420785108082 -0.950312246532708 0.343452352886284 HOXB4 other 1 1 1 2.19590035975285 -0.950312246532708 2.29723625404385e-07 142.998427242211 36.1270886733565 3.95820511680676 0.000114723688253391 -87.042035376323 77.009750306549 -1.13027292037487 0.260107211228885 PAQR7 other 0.00221637353790151 1 1 3.95820511680676 -1.13027292037487 0.965613056328105 0.877537581179867 8.63291867838746 0.101650161882885 0.919164067615576 -2.38206466316282 14.309070280209 -0.166472357498829 0.867999435988084 PAPPA other 1 1 1 0.101650161882885 -0.166472357498829 0.695360727144901 -6.41437667560322 8.85868201099255 -0.724077991245622 0.470501177593781 -23.8281389633601 36.8917652104225 -0.645893164164134 0.519646579101625 MAFA other 1 1 1 -0.724077991245622 -0.645893164164134 2.65174081789653e-15 1192.73108181326 140.348186156607 8.49837190259338 1.49612813117664e-14 -111.599173740293 252.468132719018 -0.442032713350389 0.659081659663148 NGRN other 3.57401627436094e-11 1 2.07677545888629e-10 8.49837190259338 -0.442032713350389 0.0174474267114616 56.7074772016569 21.5900047205745 2.62656159345888 0.00950238978263095 20.0394461817211 41.170631088881 0.486741292317309 0.627138217323874 GRID1 other 1 1 1 2.62656159345888 0.486741292317309 3.96397018808824e-05 4964.73750185547 2521.83156893452 1.96870305020136 0.0508302277770173 -14211.4514761834 4407.431445914 -3.22442938717933 0.00154917742343525 RPS17 essential 0.305146425079033 1 1 1.96870305020136 -3.22442938717933 0.2617365944232 -1.5967385740402 3.53396543846976 -0.451826312917084 0.652038179167916 -12.6669556257271 7.93433465859943 -1.59647357601665 0.112460061274216 HCAR2 other 1 1 1 -0.451826312917084 -1.59647357601665 0.0906228123546 10.3683302171725 4.7080212584698 2.20226920142293 0.029172755699815 3.17878613548109 15.4129158414637 0.20624171105441 0.836881775873478 CCDC87 other 1 1 1 2.20226920142293 0.20624171105441 0.675438229615193 -29.1045269653284 76.7167024195378 -0.379376668279686 0.704927413374779 -237.682808046709 271.068075163845 -0.876838070669307 0.381931562015503 C1orf116 other 1 1 1 -0.379376668279686 -0.876838070669307 2.62913034186412e-06 214.172988491146 46.6846083655513 4.58765738836495 1.00176078311219e-05 -123.485099463937 128.210765933873 -0.963141422364062 0.337173499635155 TMEM198B other 0.0230192171638612 1 0.101718789917212 4.58765738836495 -0.963141422364062 0.000118213160556379 1925.6956956082 486.874223688613 3.95522211264116 0.000118523535237103 -118.466727438469 993.072371981153 -0.11929314597901 0.905205986281492 CRIP2 other 0.859646103565984 1 1 3.95522211264116 -0.11929314597901 3.56918283260005e-13 126.191697080292 27.1218084889623 4.65277590657894 7.20921557984474e-06 -72.2190510948911 42.9941934635053 -1.67973964103299 0.0951177125378345 DDX28 other 4.59175371413997e-09 1 0.0740406877549327 4.65277590657894 -1.67973964103299 0.000178772448774687 175.131649905547 49.1161789099813 3.56566112821038 0.000482133950583809 -137.815111658058 157.91008104953 -0.87274422723417 0.38414385743409 ACBD3 other 1 1 1 3.56566112821038 -0.87274422723417 9.13671344234991e-13 738.08400839671 97.1185843980719 7.5998225568387 2.70393254576252e-12 280.60709246705 219.674403660085 1.27737728106571 0.203391493179819 C16orf72 essential 1.16164174706037e-08 1 3.64760500423363e-08 7.5998225568387 1.27737728106571 0.992461745876098 -1.24990897837326 10.390856075221 -0.120289316811337 0.904412820102247 0.241905143328759 43.8858336372342 0.00551214647825485 0.995609193457399 PLCXD3 other 1 1 1 -0.120289316811337 0.00551214647825485 0.0177215020596838 72.0294236866107 31.5400094051095 2.28374769206448 0.0237444605375324 -1.15303212357231 46.8531740386123 -0.0246094773135772 0.980398113805481 RRP7BP other 1 1 1 2.28374769206448 -0.0246094773135772 0.677697373816214 -1.40705945510669 4.09677569673091 -0.34345533152559 0.731733675179618 14.7292309757081 20.1583477793194 0.730676498736613 0.466108976702144 VMO1 other 1 1 1 -0.34345533152559 0.730676498736613 2.70258158884724e-10 247.862791258087 50.4607473316351 4.91199208028169 2.31939171575623e-06 -106.22455372866 81.6458746223943 -1.30104006136182 0.195226541320295 ALG12 other 3.13958903176384e-06 1 0.0247548677822662 4.91199208028169 -1.30104006136182 0.145470578098919 14.2701468806784 9.65938868501933 1.47733436825146 0.141682546448003 -13.2718125378559 27.1818675935561 -0.488259774357896 0.626078845346842 LCK og 1 1 1 1.47733436825146 -0.488259774357896 0.0986303793219415 30.9515381784119 19.564635044746 1.58201459457961 0.115780927107953 -14.2263226464809 37.9397628044249 -0.374971312282999 0.708218593566058 GALNT9 other 1 1 1 1.58201459457961 -0.374971312282999 8.26728863771776e-05 3249.30515366429 931.734007954941 3.48737421401649 0.000650850493289152 -1264.30789598109 1686.20948774482 -0.749792896535058 0.454628671781412 COL18A1 other 0.612936779600395 1 1 3.48737421401649 -0.749792896535058 0.776035990699857 2.59920676416547 6.25731763513922 0.415386738491444 0.678460412327779 -1.35417009007931 9.60659591262419 -0.140962532659438 0.888091221488021 ADGRG3 other 1 1 1 0.415386738491444 -0.140962532659438 3.47802030380215e-06 3110.27527962628 853.992393849675 3.6420409619875 0.00038171526158198 -9497.80356365612 3292.1799229774 -2.88495883756755 0.00454390897024273 RPL35A other 0.0300709635466734 1 1 3.6420409619875 -2.88495883756755 0.0224624149831854 7.65684330790685 5.65219626453413 1.35466692052986 0.177705817993381 -11.0631573641588 8.46511595550461 -1.30691149681945 0.193385388217797 SLC25A18 other 1 1 1 1.35466692052986 -1.30691149681945 2.06866844477356e-16 286.719314186533 32.4126062655457 8.84591975842783 6.52819299872623e-15 89.7164992805114 59.1009630285159 1.51802093710763 0.131494551957564 ZNF721 other 2.8338689024953e-12 1 9.10030104022437e-11 8.84591975842783 1.51802093710763 3.48973167155423e-08 137.876676402217 33.1073101408178 4.1645387624599 5.16270408308899e-05 -214.601257177485 90.9177355808896 -2.36038937624611 0.0195005003753336 C11orf54 other 0.000358953799736068 1 0.487823908811079 4.1645387624599 -2.36038937624611 3.59443430362836e-14 99.5559201491782 11.7111590827162 8.50094507691448 1.57647940630866e-14 -34.8798623859843 45.0206119231317 -0.774753182954027 0.439681192607579 CEP63 other 4.74285606363762e-10 1 2.18815341595643e-10 8.50094507691448 -0.774753182954027 3.17597465196752e-14 1153.29503625209 153.521119066385 7.5122891447488 4.62538497660621e-12 -772.148111832754 429.909338044691 -1.79607197030106 0.0744692478210761 SRPRA other 4.19419212538831e-10 1 6.2100418695915e-08 7.5122891447488 -1.79607197030106 0.000864995822153176 669.54997399123 174.697167951181 3.83263210184571 0.000188826652101813 350.949744689435 280.286874730351 1.25210909368148 0.212559994998862 EWSR1 essential 1 1 1 3.83263210184571 1.25210909368148 3.10266787162269e-06 79.2210180546367 34.6010479345688 2.28955545521179 0.0234610432939642 -325.353428963041 99.3922171252234 -3.27342963436595 0.00132274317720524 HMGN4 other 0.026955978468658 1 1 2.28955545521179 -3.27342963436595 0.00199256434891513 128.8348357577 47.6486512057038 2.70385063370436 0.00761983537217822 -35.1188736370051 80.2979894664117 -0.437356823880319 0.662461355292085 SPATA13 other 1 1 1 2.70385063370436 -0.437356823880319 0.0616492689065527 48.8139653044929 23.2300433211659 2.10132906898268 0.0372090759490511 120.901357334688 91.5214831370776 1.32101615042237 0.188418117227746 GJC1 other 1 1 1 2.10132906898268 1.32101615042237 7.66426233447394e-09 109.102526822421 30.769998324383 3.54574367122942 0.000518893025275982 -225.415204385174 67.8255719335159 -3.32345453136953 0.00111096636239135 CNOT10 other 8.22451991112399e-05 1 1 3.54574367122942 -3.32345453136953 2.98909240895471e-16 1414.51611493363 153.094373758757 9.23950423653449 2.59360244711934e-16 438.635369188696 312.265027574788 1.40468938387166 0.162223196825539 MTA1 other 4.08728496000466e-12 1 3.65127352505461e-12 9.23950423653449 1.40468938387166 0.000576640736989646 33.4196072464871 11.8192160885611 2.82756546593909 0.00530989365366013 -35.8581675125249 26.0425052221512 -1.37690929527105 0.17052572038213 ZNF662 other 1 1 1 2.82756546593909 -1.37690929527105 0.0423665297161389 158.791542899827 119.789094980813 1.32559264201187 0.18700349344858 -411.089106889173 324.396034813623 -1.26724454916768 0.207044908433611 CADM1 other 1 1 1 1.32559264201187 -1.26724454916768 1.81651531390412e-06 54.7957795406841 16.4652256480791 3.32797015430376 0.00109431325508167 -94.5535862459068 46.1865336260729 -2.04721114191887 0.0423369069184835 ZNF320 other 0.0161906009928274 1 1 3.32797015430376 -2.04721114191887 0.591559776508169 -34.8650740461101 52.5502268036884 -0.663461913805916 0.508059965426316 -194.399987557652 202.315151716996 -0.96087705694719 0.338170692867087 C12orf60 other 1 1 1 -0.663461913805916 -0.96087705694719 0.000114241568141531 440.224350119301 107.929471069477 4.07881504242635 7.6148809134011e-05 -689.503516262719 490.03801007989 -1.40704088678817 0.161663469951149 PYCR1 other 0.832821031751764 1 0.705366419008344 4.07881504242635 -1.40704088678817 0.0126885630981018 324.868639734084 110.052657533914 2.95193816318312 0.00369995356972843 157.092879059062 552.538810370366 0.284311031389383 0.776589140226569 NAA38 other 1 1 1 2.95193816318312 0.284311031389383 0.038990941863974 24.955057404447 16.822649114833 1.4834201934607 0.139980342190854 -174.701254662598 95.1567949313116 -1.83593042187586 0.068271766845822 SPNS2 other 1 1 1 1.4834201934607 -1.83593042187586 0.000443290289944903 246.977522161249 83.0008520308904 2.97560225127968 0.00340287790176573 -107.622009990152 144.790200977938 -0.743296226286407 0.458449680908608 AP2A2 other 1 1 1 2.97560225127968 -0.743296226286407 0.00081200028358535 96.075498041887 24.9052661235834 3.85763788128772 0.000168712200921325 106.470352082033 103.117055891635 1.03251931662908 0.303468945739312 SLC8A1 other 1 1 1 3.85763788128772 1.03251931662908 0.000276967384749017 2.89005899215807 3.04450388480201 0.949270916218921 0.344019982996886 -14.9082581124089 4.61207696831153 -3.23243914072553 0.00151117482971925 SLC25A21 other 1 1 1 0.949270916218921 -3.23243914072553 0.0047859240852773 337.331753002435 139.404600876498 2.41980358525818 0.016717034818183 -279.46436392652 262.663618743529 -1.06396297006551 0.289043946497786 PCP4 other 1 1 1 2.41980358525818 -1.06396297006551 8.25375272815252e-09 444.711722792434 68.5922794505106 6.48340784640775 1.16903307404154e-09 472.550725252354 156.459688861773 3.02027141105871 0.00296044941442186 ABAT other 8.84389604821542e-05 1 1.47134502698868e-05 6.48340784640775 3.02027141105871 5.1679173202892e-05 307.615793738184 77.4271418840566 3.97297105708517 0.000113505889242902 -730.561724804189 351.497637924583 -2.07842570185617 0.0395089122871002 SLC25A10 other 0.392968433034791 1 1 3.97297105708517 -2.07842570185617 3.03929558603521e-05 238.682976867171 50.9640404562688 4.68336055639034 6.12398800734038e-06 240.842097545956 254.996612446557 0.944491361023206 0.346388551897449 CAMK1D other 0.238007237342417 1 0.0633526559359362 4.68336055639034 0.944491361023206 4.64855583091829e-07 73.7129633104414 14.0668152842755 5.24020269128301 5.1312030246282e-07 -12.8458404740163 27.8380892541132 -0.461448354330509 0.645119741456507 LYSMD4 other 0.00436545878081537 1 0.00571564704913335 5.24020269128301 -0.461448354330509 0.301848227367531 11.2656124957128 7.5288049895901 1.49633474519389 0.136599867739699 6.21340888304565 11.1950935891869 0.555011785613568 0.579686658619455 WBP2NL other 1 1 1 1.49633474519389 0.555011785613568 0.244478718079409 9.76056754985084 27.0572437368207 0.36073768802135 0.718793118946973 75.0352075447757 45.1486288018901 1.66195983213635 0.0985683469035462 NKX2-5 other 1 1 1 0.36073768802135 1.66195983213635 7.76380618095451e-08 138.302241256996 26.1255036143042 5.293763645623 3.95147313870476e-07 -296.233019785071 105.685264028803 -2.80297374006973 0.00569792062838985 AFMID other 0.000779408502506024 1 0.00442960138848804 5.293763645623 -2.80297374006973 0.0250836566788481 -247.454593857922 871.89963869005 -0.28381086867945 0.776965830899738 -4141.16305765464 1578.41301627665 -2.62362449811983 0.00964402179600353 GAS6 other 1 1 1 -0.28381086867945 -2.62362449811983 0.0180805540087661 25.5342766170249 10.3422665170606 2.4689246380282 0.0146165553214252 -21.7585144811175 30.3511191978148 -0.716893315838055 0.474498334020693 NEB other 1 1 1 2.4689246380282 -0.716893315838055 0.882776529741113 -0.825378787878777 7.65609231049225 -0.10780679678426 0.914290194858855 -5.97954545454544 12.2770604345899 -0.487050258195228 0.626919760286359 BEGAIN other 1 1 1 -0.10780679678426 -0.487050258195228 0.170664739058924 70.5833705559243 37.5312150585787 1.8806577523738 0.0619699997223504 69.1421379851513 70.0341153981651 0.987263672740883 0.32511387654316 GPC6 other 1 1 1 1.8806577523738 0.987263672740883 0.00245325675981236 123.060664939551 37.9265126977914 3.24471342567483 0.00143856238004764 9.55453847630023 60.5585477671246 0.157773573320183 0.874839258738853 ARHGEF37 other 1 1 1 3.24471342567483 0.157773573320183 0.189698978663752 6.89386143062271 5.00601499083277 1.37711561856028 0.170462055628772 -1.46256477509722 11.0500496087152 -0.132358208957152 0.894872632552222 FAM43B other 1 1 1 1.37711561856028 -0.132358208957152 0.625142116400403 5.00407810025037 7.2331897237949 0.69182176762052 0.490186890264529 0.12651691277912 13.7213517309762 0.00922044090550535 0.992656289741497 CSMD1 other 1 1 1 0.69182176762052 0.00922044090550535 0.0126656598178003 -20.8088270091714 13.9122052660556 -1.49572455345688 0.136758748003153 -71.9246992513226 24.1084148425895 -2.98338566516874 0.00331275190488137 CALHM3 other 1 1 1 -1.49572455345688 -2.98338566516874 0.512223846367557 1.49373146134069 3.84250837325541 0.388738635350112 0.69802817920404 -11.4741546371367 12.5412328844671 -0.914914406170382 0.361724788871009 PTGDR2 other 1 1 1 0.388738635350112 -0.914914406170382 6.0361508850988e-10 41.0550324005154 7.77063736460251 5.28335456593727 4.35597136774837e-07 -7.79902454432867 16.4112783728336 -0.475223463227507 0.63531438757498 CEP57L1 other 6.8914734655173e-06 1 0.0048730251691001 5.28335456593727 -0.475223463227507 0.612786239761264 2.92754825997985 7.83587350113651 0.373608412585431 0.709219697337499 -9.80860728698768 14.9543224044709 -0.655904495148186 0.512883740506404 RIPPLY3 other 1 1 1 0.373608412585431 -0.655904495148186 0.000295901330588884 15.1523575339311 4.43807234602737 3.4141754240429 0.000819091435943102 -17.1609378134031 17.4072673868989 -0.985849038334344 0.325763644748659 GPR19 other 1 1 1 3.4141754240429 -0.985849038334344 1.89700518992498e-11 9.60892397579469 4.48360296860752 2.14312552718711 0.0336635617640624 -125.092995757112 18.3950951815213 -6.80034512040871 2.13127611635406e-10 GJD3 other 2.30941411821467e-07 3.11763070300272e-06 1 2.14312552718711 -6.80034512040871 0.0133740279545854 25.8940227009934 16.3948200641917 1.5794026771632 0.116692703566424 -110.095665101352 56.7811860421176 -1.93894620340773 0.0546913883914184 RABIF essential 1 1 1 1.5794026771632 -1.93894620340773 0.0129154704057889 146.690149179358 50.7201760197375 2.89214590111584 0.00437675543837618 88.7932805270939 101.532881385245 0.874527338490342 0.383184170066178 TMEM119 other 1 1 1 2.89214590111584 0.874527338490342 2.4321500858171e-06 68.3640004800333 37.2378729633237 1.83587286382781 0.0682926230913147 -178.198730911164 59.6027580203963 -2.98977323918775 0.00324800298748742 FANCF other 0.0213785992543323 1 1 1.83587286382781 -2.98977323918775 0.000902390169803311 -3.22563461182139 4.61085611750359 -0.699573903331386 0.485298983847454 65.6227912813515 18.2832792165032 3.58922436748206 0.000451175880394246 CALN1 other 1 1 1 -0.699573903331386 3.58922436748206 2.89497966087653e-08 30.3659468960794 73.5055029824194 0.413111204794315 0.680096069552164 -519.554468674975 109.300345319908 -4.75345679059208 4.53179445615498e-06 SMDT1 other 0.000299601445104112 0.0659466729259673 1 0.413111204794315 -4.75345679059208 0.853730639602255 -3.07960145098225 14.3246339224577 -0.214986398092459 0.830093028235537 -11.9866961888161 21.3791563774035 -0.560672085334731 0.575923731308921 C2CD4C other 1 1 1 -0.214986398092459 -0.560672085334731 0.0167995714726052 -40.8793405282703 61.1190297893524 -0.668847994956096 0.504593831654553 -277.537886095744 108.04114460271 -2.56881660330711 0.0111548310606394 CHST6 other 1 1 1 -0.668847994956096 -2.56881660330711 5.92927432898595e-06 19.6197755874419 4.33010775447473 4.5310132449168 1.2928619569765e-05 2.62855858350681 11.8590109026646 0.221650743479474 0.824925740031741 POTEC other 0.0500193582393255 1 0.12986798357829 4.5310132449168 0.221650743479474 2.25162693809685e-09 524.053039538717 141.182971395472 3.71187144142742 0.000285238497676875 -560.472409390445 249.156951438653 -2.24947530524126 0.0258726177391496 RUVBL2 essential 2.49322650855465e-05 1 1 3.71187144142742 -2.24947530524126 7.19329441589296e-06 71.1169488406331 18.388385374367 3.8674928435951 0.000161852066489618 -60.2612256164887 33.270199239278 -1.81126735019205 0.0720482178443667 GDPGP1 other 0.0601934876721923 1 1 3.8674928435951 -1.81126735019205 0.00573153585129701 294.185089755932 100.018503617253 2.94130664943468 0.00377320542148808 41.3686647035505 162.226873226705 0.255005005525439 0.79905946538242 WT1-AS other 1 1 1 2.94130664943468 0.255005005525439 2.76167277534152e-15 894.741826942949 111.677063261912 8.01186744000013 2.67776914045412e-13 159.545401721413 310.565126305216 0.513726069695977 0.608184632199253 PRR36 other 3.72080173021763e-11 1 3.66318818414124e-09 8.01186744000013 0.513726069695977 0.00321913284532777 -2.93783368981324 9.55936599260813 -0.307325160694229 0.759013801664396 -53.6862621842701 16.9179874490803 -3.17332438895908 0.00182193266600034 LINC01547 other 1 1 1 -0.307325160694229 -3.17332438895908 0.00495183806927733 -92.4680392508947 531.099830179232 -0.174106700843209 0.862011764799297 -2817.69195225888 939.930563190988 -2.997766071882 0.00317472970552533 PTTG1IP other 1 1 1 -0.174106700843209 -2.997766071882 1.69364073511463e-05 335.792619521263 83.0393099875188 4.04377901949973 8.3365511295151e-05 -73.8678455837745 133.852604302531 -0.551859606831555 0.581854995879292 DDX41 essential 0.136473570435537 1 0.768796745163883 4.04377901949973 -0.551859606831555 2.57276957539608e-08 72.4859248464278 12.0307400879428 6.02505949896407 2.04572253443513e-08 31.4992621151471 41.3371489274513 0.762008579024883 0.447601457182291 ABHD16B other 0.000267130665013375 1 0.000245711733611004 6.02505949896407 0.762008579024883 0.0167479908569514 -16.5432175874546 8.76187295326764 -1.88809147036137 0.0608945363700322 -50.0830145891082 17.5018666112207 -2.86158132167452 0.00480180114469785 CCDC60 other 1 1 1 -1.88809147036137 -2.86158132167452 1.04963477473255e-06 783.978489442618 212.952682545482 3.68146801473223 0.000320291359816634 -1311.34700831168 542.369661820279 -2.41781039874279 0.0167818633090595 DAZAP2 other 0.00956427206736297 1 1 3.68146801473223 -2.41781039874279 0.295638446947193 -11.966897582756 10.6333108342581 -1.12541594704458 0.262141296119073 -31.3050292374269 19.9793366684748 -1.56687029989453 0.119171240567342 CCBE1 other 1 1 1 -1.12541594704458 -1.56687029989453 0.000963999898545688 93.1485592315897 214.181892441938 0.434903988239067 0.66423703014514 -2506.37815723942 703.099348637802 -3.56475676175113 0.000484514871737796 SELENOF other 1 1 1 0.434903988239067 -3.56475676175113 1.51659014869458e-09 287.773343036274 44.3771369571321 6.48472079923183 2.48646440505145e-09 -107.943256456188 186.729699134998 -0.578072245369759 0.564375829915783 ZNF623 other 1.69600276328515e-05 1 3.09639412361057e-05 6.48472079923183 -0.578072245369759 0.211605767191936 12.4275630690054 8.27386836739585 1.5020257172543 0.135165085740689 -12.4544486246152 32.8299673877574 -0.379362199100434 0.704948372714668 EPHA10 other 1 1 1 1.5020257172543 -0.379362199100434 2.16451906647272e-10 13.6854071353394 22.4937929598188 0.60840815774316 0.543875282518894 -144.51000923599 32.3495833281824 -4.46713664809696 1.59176152930318e-05 CCDC125 other 2.52447858722713e-06 0.230646245596031 1 0.60840815774316 -4.46713664809696 6.95347024045969e-09 85.9027460660291 17.4888416696974 4.91186024142875 2.26982314345365e-06 -76.1040182279921 46.4901755595449 -1.6369914140358 0.103660987733076 JRKL other 7.4861060608789e-05 1 0.0242439809952285 4.91186024142875 -1.6369914140358 7.86896603992933e-29 436.449126174361 33.4250453548704 13.0575477621832 1.47103620905446e-26 196.963713506415 78.3186853821287 2.51490065934329 0.0129535523804051 KIAA2026 other 1.13919021360057e-24 1 2.12888360174362e-22 13.0575477621832 2.51490065934329 0.26079159526979 8.10410922232633 7.68852532046305 1.05405248530004 0.293499188313006 -6.97338241199303 11.6256485461116 -0.599827388926648 0.549497147186703 SYNDIG1L other 1 1 1 1.05405248530004 -0.599827388926648 0.00231960169604683 134.556511576004 43.815783600362 3.07095983500549 0.00252844278337933 -126.066959933281 182.381642699595 -0.691226145719767 0.490477774291803 FHL3 other 1 1 1 3.07095983500549 -0.691226145719767 0.000125223157872415 9.03404086347555 3.81219076653515 2.36977670235702 0.0190217049371832 -14.0018475856682 7.81006416525919 -1.79279546100932 0.0749432545464642 PMCH other 0.907492225101394 1 1 2.36977670235702 -1.79279546100932 0.0873686456850587 8.88668638401867 4.62053008285863 1.92330451802202 0.0563489195427439 -0.233114876815448 6.91462547322286 -0.0337133048952823 0.973150889724907 C19orf71 other 1 1 1 1.92330451802202 -0.0337133048952823 2.49009852392255e-05 227.846549768686 70.5929700710439 3.22760962655891 0.00152920678540498 -422.271152734814 252.083996198211 -1.67512082918103 0.0959666107515074 CCDC159 other 0.19741501097658 1 1 3.22760962655891 -1.67512082918103 0.00651179841139728 81.8664480087598 58.4343499417203 1.40099869495271 0.163226346539055 -230.064497323384 111.911255649785 -2.05577621292489 0.0414926227758064 RIPK4 other 1 1 1 1.40099869495271 -2.05577621292489 1.95855364308052e-19 625.482565191025 65.9832531425574 9.47941387248162 4.67079973156828e-17 -470.83484162896 274.630607545229 -1.714429596313 0.0884747374213337 SF3A3 essential 2.75842695091461e-15 1 6.60404374046439e-13 9.47941387248162 -1.714429596313 0.579420083721556 1.69948396235947 5.98446694135533 0.283982513231927 0.776797955115735 -5.32394009916036 9.05428785664526 -0.58800208072167 0.557375739790323 TRIM61 other 1 1 1 0.283982513231927 -0.58800208072167 0.612613899815209 56.3893446285902 57.0206153421928 0.988929079249422 0.324249084196765 57.6525201402672 128.527848630333 0.448560531858627 0.654379213123307 GRIN2A other 1 1 1 0.988929079249422 0.448560531858627 2.97266510923047e-13 59.5354714300216 24.632684594772 2.41692988033701 0.0170399507428474 -142.373138468825 35.5873212905159 -4.00067027542102 0.000105436393400146 GTF2H2C essential 3.82998172673254e-09 1 1 2.41692988033701 -4.00067027542102 4.59491691573725e-14 161.217963753448 21.4591658346323 7.51277868840845 4.40423739362034e-12 -73.5196002472764 39.7682759848444 -1.84869970916754 0.0664186914798678 ASB7 other 6.04966761125966e-10 1 5.91533124337148e-08 7.51277868840845 -1.84869970916754 0.00140626725312417 26.0431687566484 7.26337673553778 3.58554563598857 0.000451052650425043 7.64001497515241 12.986710638444 0.588294849084879 0.557196186429938 SH2D7 other 1 1 1 3.58554563598857 0.588294849084879 0.525287072647337 11.6044181297129 12.3274914235812 0.941344652450127 0.348083204284413 25.39959064478 26.0655559254073 0.974450371113006 0.33144471735145 GPR132 other 1 1 1 0.941344652450127 0.974450371113006 0.283828675835426 66.1594665017438 172.1583929236 0.38429416874903 0.701290551521442 -410.51718002271 329.711239056215 -1.24508094172889 0.214993260194456 MX2 other 1 1 1 0.38429416874903 -1.24508094172889 1.04164703415889e-13 685.644717654359 101.829221474283 6.73328056256935 3.42028684531351e-10 -160.079762643499 197.157529889277 -0.81193836590162 0.418130981244267 EP400 other 1.35820356783977e-09 1 4.37728310463223e-06 6.73328056256935 -0.81193836590162 0.616839579013635 18.4337622093494 22.5515789341698 0.817404504720458 0.414976707522361 32.5456355486203 39.9500609734903 0.814657969363717 0.416542656607376 MEX3B other 1 1 1 0.817404504720458 0.814657969363717 1.89481314781432e-06 145.965120105298 27.5486069299585 5.29845739482979 4.09321088311405e-07 91.9100581331577 50.9823171793581 1.80278306711352 0.0734297717266289 PI4KAP2 other 0.0168543629498084 1 0.00458439618908774 5.29845739482979 1.80278306711352 0.0632196760658297 53.5503185034117 30.6144044291595 1.74918700859672 0.0823316932397907 -177.218313316716 139.914905506345 -1.26661496625661 0.207282759154261 FAM46C other 1 1 1 1.74918700859672 -1.26661496625661 2.76858450491844e-14 162.247790439656 20.5321891149727 7.90211845074716 5.9310431512178e-13 -198.435598367746 96.0929515948798 -2.06503801865026 0.0406760663366352 COA5 other 3.66145300775463e-10 1 8.08401181510986e-09 7.90211845074716 -2.06503801865026 1.72697160566602e-13 186.345694384081 26.1398394438196 7.12880026614471 3.82388716096702e-11 -218.152802086148 108.806153078319 -2.00496751253691 0.0467418784993868 UTP11 other 2.23988217254882e-09 1 5.04064805558673e-07 7.12880026614471 -2.00496751253691 0.00118706728589289 54.0122258180512 54.8879440646493 0.98404534435528 0.326656983116567 -300.854848375883 106.008483102926 -2.8380261613948 0.00515974324172042 PSMG1 essential 1 1 1 0.98404534435528 -2.8380261613948 1.50807921765162e-08 406.114146066359 63.9085169281699 6.35461696792013 2.27600057610341e-09 256.448231350063 105.480071528522 2.43124817450203 0.0162023292805458 PRR14L other 0.000159072195877893 1 2.83953831874661e-05 6.35461696792013 2.43124817450203 0.0225956997083045 22.0845360973986 15.6232717851961 1.41356665883038 0.159494383838265 -24.8020325144404 23.2086129906401 -1.06865638736976 0.286886003794254 SERHL2 other 1 1 1 1.41356665883038 -1.06865638736976 0.968630880712997 1.18213976344886 11.4050290671799 0.10365074534099 0.917594848716853 -3.01025318415218 20.4976015161456 -0.146858801103195 0.883454741559579 PCBP3 other 1 1 1 0.10365074534099 -0.146858801103195 4.49956585380284e-10 246.003010740771 47.549285753785 5.173642607685 7.10122432149847e-07 -165.085071897598 77.0779432519833 -2.14179394172341 0.0337929915341706 SETD3 other 5.1691012528487e-06 1 0.00782980993688421 5.173642607685 -2.14179394172341 0.713974583840121 -0.281827474245326 5.88048734090511 -0.0479258704095685 0.961837418515165 -6.60916142221504 8.79698741240446 -0.751298269779901 0.453619734348693 TNFAIP8L3 other 1 1 1 -0.0479258704095685 -0.751298269779901 0.000103951370842785 266.258880218662 60.4395629015748 4.40537402052794 2.06593919062384e-05 150.411641578862 95.9480460659526 1.5676363172156 0.119191773328097 ZNRF3 other 0.760716131827502 1 0.203495010276449 4.40537402052794 1.5676363172156 0.781974372761892 19.1460493420415 34.0115571119621 0.562927750676482 0.57433014527909 -36.4823543091919 135.149539031658 -0.269940649228897 0.7875794197973 FBXL7 other 1 1 1 0.562927750676482 -0.269940649228897 3.72666483539836e-10 120.768902264259 30.2005731003909 3.99889438729545 0.000102264427887633 -132.487933505303 47.7033637578977 -2.77732895687818 0.00622671294942069 TANGO2 other 4.30062576339694e-06 1 0.934799135320853 3.99889438729545 -2.77732895687818 3.0581851489875e-06 45.0852284773754 15.3437395116687 2.93834683801096 0.00380406373668031 -84.563845338392 32.8010865965518 -2.57808060990521 0.0108662683244299 SMG1P5 other 0.0265909198704463 1 1 2.93834683801096 -2.57808060990521 0.00491828996328995 44.5142022321214 31.0490830319004 1.4336720406972 0.153693104373648 -106.289241749294 55.7768004208541 -1.9056174062927 0.0585632547166074 SFXN4 other 1 1 1 1.4336720406972 -1.9056174062927 0.041886830942246 -3.83074388344383 2.43635321395029 -1.57232697685599 0.117981684353465 -17.2350017150537 6.89152657642206 -2.50089751870358 0.0134625678173052 FAM167B other 1 1 1 -1.57232697685599 -2.50089751870358 0.000422320853470285 37.5063520871142 49.7769252709985 0.753488727616659 0.45233734809337 -218.887441016334 74.7378434188469 -2.92873638043905 0.00393495593737846 MRPL54 essential 1 1 1 0.753488727616659 -2.92873638043905 1.27715424445957e-13 49.0943948969346 5.94580502277497 8.2569802926403 6.13430414851151e-14 19.325335183982 26.2332827096897 0.73667239429566 0.462435132344449 ZNF438 other 1.66183310289079e-09 1 8.45000396457461e-10 8.2569802926403 0.73667239429566 0.000114626135257185 136.626305984588 31.1188400753393 4.39046910661879 2.11582628043631e-05 70.4150543400144 128.058974640264 0.549864267911095 0.583224861082829 HMCES other 0.83550989988962 1 0.208218464257737 4.39046910661879 0.549864267911095 0.00050031297111933 34.571592673299 17.0031499947576 2.03324635046789 0.0438775064440937 -47.6670890217837 26.9458710586097 -1.76899417792446 0.0790266796157902 DGCR6 other 1 1 1 2.03324635046789 -1.76899417792446 0.356038992243241 -32.1468687722688 25.5976811997822 -1.25585081403945 0.211097034956069 -82.4658959737045 66.5586591743207 -1.23899575196853 0.217256883193165 C11orf88 other 1 1 1 -1.25585081403945 -1.23899575196853 3.87537785778007e-06 26.3204254806778 6.36816860840195 4.13312321001544 5.89389685236598e-05 -4.76022192930202 12.6981826641881 -0.374874267853067 0.708276506127403 ZNF530 other 0.0333631279776286 1 0.552611768877834 4.13312321001544 -0.374874267853067 0.0189473133158397 58.2593397671771 65.3857635052448 0.891009550764119 0.374296198932197 -246.607081592835 114.106204642464 -2.16120659139916 0.0322047629538613 NDUFB1 other 1 1 1 0.891009550764119 -2.16120659139916 3.64881102524012e-07 107.29130594953 22.1602304391718 4.84161508356319 3.10607786323391e-06 -36.7086793147909 38.8888312642346 -0.943938866801361 0.34667944799107 KLHL25 other 0.00345615380310744 1 0.0328685159487413 4.84161508356319 -0.943938866801361 6.63387065675237e-31 159.227767738398 10.7645386799871 14.7918803092256 4.18943530431173e-31 266.929882717104 100.024900486675 2.66863432423672 0.00845413763277234 TRMT12 other 9.62110261348797e-27 1 6.08389794892149e-27 14.7918803092256 2.66863432423672 5.72345035284515e-08 35.9534756254835 6.54858711319102 5.49026454165378 1.6598144406686e-07 -42.0052080646548 27.1130221724715 -1.54926322109911 0.123411806399126 GUSBP1 other 0.000580357865778498 1 0.00190513501499942 5.49026454165378 -1.54926322109911 0.309166346261423 -6.30018627755355 6.16643766617858 -1.02168976946099 0.308530048326547 11.0654765600745 17.5404976551398 0.630853056602535 0.52907173161825 GPR1 other 1 1 1 -1.02168976946099 0.630853056602535 3.13937995399226e-05 7.83498490854213 2.04393115276461 3.83329198634923 0.00018601168472964 -18.4601440052366 11.1635090194053 -1.65361482425891 0.10031112473974 BMP8A other 0.245436724803115 1 1 3.83329198634923 -1.65361482425891 9.44389991785941e-05 367.163317845033 82.4361065404475 4.45391386436819 1.72718770203307e-05 98.5793042823017 374.289109429716 0.263377431506094 0.792652532735537 ALYREF essential 0.694976594955274 1 0.17130948246852 4.45391386436819 0.263377431506094 0.493998996921754 -0.443191423344062 27.2225855425866 -0.0162802839815028 0.987035001625916 -127.879866899201 110.213517272966 -1.16029204097063 0.247992979923611 RFLNB other 1 1 1 -0.0162802839815028 -1.16029204097063 0.02414922957294 37.9508313804263 13.7965748730515 2.75074297277614 0.00664047356737944 -8.7053453855595 52.4558084455305 -0.165955794859192 0.868403906853349 NOG other 1 1 1 2.75074297277614 -0.165955794859192 0.126580651713157 -78.303767069152 38.2561494883461 -2.04682823850334 0.0423749910465654 -90.0124332737508 92.2057354844714 -0.976212952489382 0.330489927372064 UPP1 other 1 1 1 -2.04682823850334 -0.976212952489382 0.00553055642218376 62.9041131377834 26.5529772260713 2.36900414602172 0.0191821685084477 -40.1645961635836 43.4347388880041 -0.924711352982861 0.356684838356062 TRIM52 other 1 1 1 2.36900414602172 -0.924711352982861 7.07674464681743e-08 295.397880287562 86.4858849400558 3.41556174735687 0.000827310292235076 -151.309361569851 134.404027737173 -1.12577996446458 0.262131434273988 CMTM4 other 0.00071319432550626 1 1 3.41556174735687 -1.12577996446458 1.59345338290143e-05 200.975363002996 136.781813593863 1.46931348344115 0.143800976713423 -855.358161870034 301.131451184107 -2.84048098764377 0.00511805293326027 TMEM50A other 0.12883070600758 1 1 1.46931348344115 -2.84048098764377 0.273508469049731 70.1786681181638 46.2114755778528 1.51864157637497 0.130971750536644 108.55359901055 78.6129204395764 1.38086205681655 0.169389061790718 ASCL2 other 1 1 1 1.51864157637497 1.38086205681655 2.81548804317171e-07 73.645984153607 17.0057755944345 4.33064541776672 2.71710023007226e-05 -117.673271125158 52.0621324673682 -2.26024685406259 0.0252551287534101 TBK1 other 0.00269329586209806 1 0.264401023388331 4.33064541776672 -2.26024685406259 4.11123909969387e-12 1057.94656357809 134.888511972713 7.84311835089486 7.60279815874909e-13 705.395232696915 270.464681009866 2.60808631301913 0.0100256184267371 CBX6 other 5.12054829866871e-08 1 1.03428466151623e-08 7.84311835089486 2.60808631301913 0.0036534669269419 290.521796175193 91.4808918157487 3.17576480081034 0.00180548271295384 174.253400285761 215.238820936333 0.809581652267577 0.419429778534041 MACC1 other 1 1 1 3.17576480081034 0.809581652267577 5.7474009346619e-12 364.968283973955 58.7235720149587 6.21502186346883 5.69693998452786e-09 -97.125673878037 123.909347224407 -0.783844609415435 0.434474597114814 TBL3 essential 7.12160449813956e-08 1 7.00495740497546e-05 6.21502186346883 -0.783844609415435 4.67237575589686e-15 593.394613672982 64.8883091282607 9.14486171153044 5.20285824859361e-16 376.206808358269 103.260652565404 3.6432735898118 0.000374927852437077 KREMEN1 other 6.27079550198917e-11 1 7.31053612509889e-12 9.14486171153044 3.6432735898118 1.23356469996541e-07 40.8015496704057 13.1601881793211 3.10037737412585 0.00234350370788894 -95.4946481117408 28.3388603922679 -3.36974200055681 0.000975801827069572 TRAIP essential 0.00121789842827585 1 1 3.10037737412585 -3.36974200055681 4.92823153423795e-08 126.612494102317 26.7740286596866 4.72892950521696 5.35524737501436e-06 -66.5430324953006 42.9475331813367 -1.54940290084501 0.123495218420174 CHEK2 ts 0.000501447558608711 1 0.0556785069580243 4.72892950521696 -1.54940290084501 0.806407296965538 6.56849637510589 12.1201524675464 0.541948328842733 0.58863738629738 -12.3195712895835 49.1184171547086 -0.250813686662184 0.802292487967162 FOXL2 other 1 1 1 0.541948328842733 -0.250813686662184 3.67447258227431e-06 12.3616583438512 3.08396008803419 4.00837170098752 9.89662894570834e-05 -3.45645612687264 5.08136936978323 -0.6802213882397 0.497487616281379 AIFM3 other 0.0316996749672805 1 0.905838447400684 4.00837170098752 -0.6802213882397 0.996284771725359 -2.50140365999976 55.192996916898 -0.0453210334594808 0.963911302815043 -8.90600137453844 103.993643024281 -0.085639863317982 0.931866156192758 B3GALT5 other 1 1 1 -0.0453210334594808 -0.085639863317982 7.78472810394872e-12 1266.2163757338 161.03854557966 7.86281552143956 9.39014178139625e-13 1379.8257481408 491.487075185708 2.80745073025457 0.00571189192341142 ZNF703 other 9.60557600746233e-08 1 1.27593246525612e-08 7.86281552143956 2.80745073025457 0.76583530860659 4.28211325966851 6.04999590808893 0.70778779435921 0.480139968689776 8.42040745856356 19.6957416606068 0.427524264059835 0.669590867767462 SLC35F3 other 1 1 1 0.70778779435921 0.427524264059835 0.0470968501579743 -0.293731895460939 2.37427642164205 -0.12371427892031 0.901718944759571 -13.2140173289743 5.98538571779198 -2.20771357971045 0.0288918758766835 C9orf66 other 1 1 1 -0.12371427892031 -2.20771357971045 0.0789604281193118 18.2329404805796 33.356086802117 0.546615092733912 0.585501091337953 -76.9682044508906 49.7538703519832 -1.54697923812519 0.124094045896522 TUBA8 other 1 1 1 0.546615092733912 -1.54697923812519 0.0893576323095344 33.8076317171363 17.9936987153023 1.87885949698521 0.0621910617255691 -27.8300467605213 78.1203834850811 -0.356245649585631 0.722153867656399 EMILIN3 other 1 1 1 1.87885949698521 -0.356245649585631 0.982912266974678 -4.08296317844641 29.1670015430377 -0.13998570173289 0.888853026036495 -8.44415229868998 46.0834697439578 -0.183236035515688 0.854852289597661 OLFML1 other 1 1 1 -0.13998570173289 -0.183236035515688 0.175599744890972 -3.06438803324846 2.21956312035575 -1.38062666708811 0.169368692445243 -8.53785320874511 4.61002331465439 -1.85201952918652 0.0659130108256966 FAM162B other 1 1 1 -1.38062666708811 -1.85201952918652 0.00322473570365881 74.5920726921451 23.1174545417001 3.22665596930636 0.001537957937699 -23.4474430960576 90.8729875143186 -0.258024345159369 0.796741790940016 RBM12B other 1 1 1 3.22665596930636 -0.258024345159369 1.3004033368134e-06 51.8239886499917 12.0410036342509 4.30395922334723 2.95158903319382e-05 -58.361550279439 38.7122105587056 -1.50757472738313 0.133685851548259 LIN9 other 0.0117400413247513 1 0.286156556768141 4.30395922334723 -1.50757472738313 1.12149681398654e-17 161.53137492647 18.0885722963851 8.93002345789063 1.11683027233237e-15 -39.8884500414172 60.0850264354627 -0.663866730328584 0.507755563622678 BTBD9 other 1.5584319727157e-13 1 1.56546099272828e-11 8.93002345789063 -0.663866730328584 2.31916399241577e-07 219.892762107504 51.4119798777589 4.27707243779247 3.43201734086989e-05 -197.47998344273 106.237752383002 -1.85884941099644 0.0650895981374883 NUDT14 other 0.00223660175428577 1 0.330091427844866 4.27707243779247 -1.85884941099644 0.0672298411993341 -1121.07564067236 601.592739383674 -1.86351258464471 0.0643068102176878 -2908.32670581003 1460.75066685751 -1.99098091946565 0.0482636018782243 GPR39 other 1 1 1 -1.86351258464471 -1.99098091946565 0.0436402888218699 -85.6089504420472 67.3354278616028 -1.27138050742029 0.205510173925383 -324.540412847757 128.958263234264 -2.51663138684026 0.0128720418467331 FAM3B other 1 1 1 -1.27138050742029 -2.51663138684026 3.96820666628713e-05 17.7392843098703 4.04255162024559 4.38814045590161 2.14424648744268e-05 8.69874143566635 11.634386896434 0.747675104249159 0.455826686225544 ZNF730 other 0.30543286710412 1 0.210800872180489 4.38814045590161 0.747675104249159 0.00445379452212461 389.104455071734 134.4009809886 2.89510130216042 0.00434905877412776 77.1651145230297 200.7802808131 0.384326160968269 0.701273860873711 TOB2 other 1 1 1 2.89510130216042 0.384326160968269 0.000701004081844086 45.0676229508197 16.1736291789715 2.7864879583993 0.00598996995899605 -45.3012295081968 35.6528149795126 -1.2706213950912 0.205754997555718 SCN5A other 1 1 1 2.7864879583993 -1.2706213950912 0.122760514233287 8.48326437093481 9.67316749127064 0.876989298344143 0.381858472705508 32.0549061282324 15.5446856007677 2.06211350628084 0.0408772412760073 ARSI other 1 1 1 0.876989298344143 2.06211350628084 7.96803507570234e-05 31.8335983297198 11.2318272559369 2.83423147492704 0.00523122001051481 -90.0988222382827 36.8529834971559 -2.44481758838429 0.0156587824497579 TTC32 other 0.592264047176955 1 1 2.83423147492704 -2.44481758838429 2.49779733755563e-10 160.818828840056 24.1419730127628 6.66137886721346 5.9454134372417e-10 -52.7136487627935 119.961987333079 -0.439419602281447 0.661044845804049 DNAH2 other 2.90518808331095e-06 1 7.5589986441091e-06 6.66137886721346 -0.439419602281447 0.0152672893188219 4.35011610175366 3.23744808976662 1.34368674991396 0.181039055623687 -24.682097802731 12.7679369679392 -1.93313123840671 0.0550666427174826 HTR7P1 other 1 1 1 1.34368674991396 -1.93313123840671 2.58300507445643e-05 40.3763647391833 27.6751599651557 1.45893880252251 0.146645352578146 -219.692209192613 65.5692176782637 -3.35053881945951 0.0010174498256196 KMT5A other 0.204367361490993 1 1 1.45893880252251 -3.35053881945951 3.69093871666529e-06 27.0581537553241 6.31751932709395 4.28303458277994 3.1902129479955e-05 -8.07223152224335 12.6278711929016 -0.639239298448098 0.523592947858917 KCNH8 other 0.0318343464312381 1 0.308334081423765 4.28303458277994 -0.639239298448098 8.74055676456424e-12 597.060991105465 76.7900150227528 7.77524253548533 1.05758419079359e-12 393.515421046552 131.988241363942 2.98144302083305 0.00334219551115695 SMTN other 1.0771862156649e-07 1 1.43545902216413e-08 7.77524253548533 2.98144302083305 0.000283833887224494 319.006224819079 93.4034255100668 3.41535894510312 0.000836883192581507 -31.7955229675459 197.085379624519 -0.161328674040265 0.872070487906612 NPW other 1 1 1 3.41535894510312 -0.161328674040265 1.42181485203254e-08 8.67341562547043 3.40664390285145 2.54602942744047 0.0118585932414409 -27.5635706758994 6.81920983012008 -4.04204759239884 8.2778402832993e-05 PP2D1 other 0.000150228957265758 1 1 2.54602942744047 -4.04204759239884 1.71108631546318e-10 370.859685147159 107.34318811065 3.45489724755402 0.000711373490809424 -2527.50499657769 426.680733726499 -5.92364453511465 1.98355647115155e-08 COA3 other 2.00436650993357e-06 0.000290015791647068 1 3.45489724755402 -5.92364453511465 0.00142865936338319 19.9475072208966 5.9215413813002 3.36863426875465 0.000979429537602093 47.1555946251412 26.8858943377025 1.75391579066849 0.0816649029422507 NPB other 1 1 1 3.36863426875465 1.75391579066849 0.242670595239903 27.7783067233045 19.6757465714188 1.41180445796428 0.160011903240192 -26.1206972315805 60.2842931577521 -0.433291921715458 0.66540508726107 ST6GALNAC3 other 1 1 1 1.41180445796428 -0.433291921715458 4.98426730756702e-07 689.036392402188 218.538962192936 3.15292241478604 0.00195265162832548 -1542.74328553633 589.648683785232 -2.61637705291349 0.0097959443688249 PTP4A2 other 0.00466477577315197 1 1 3.15292241478604 -2.61637705291349 0.000201960460026818 11745.2030371349 3223.75582881232 3.64332898048982 0.000376508748181367 -27373.5318354971 13691.3889548519 -1.9993246796043 0.0474814048966481 ACTG1 other 1 1 1 3.64332898048982 -1.9993246796043 0.720213073748216 -8.16971672479524 14.7935384987462 -0.552248992050661 0.581578365180635 -21.8231659096439 28.332025093961 -0.770264950608686 0.442322755148659 TMPRSS2 other 1 1 1 -0.552248992050661 -0.770264950608686 2.13058724997417e-07 198.751828336307 82.8510632270829 2.39890498196211 0.0176398237041639 -341.640270755409 130.183396543788 -2.62429987099389 0.00955710302783992 DENND5A other 0.00206368681032498 1 1 2.39890498196211 -2.62429987099389 1.98731641369778e-15 186.88181558664 49.1254229327319 3.80417723512609 0.000204737407159571 -580.69850517738 109.076024733649 -5.32379600920897 3.53478309577752e-07 DIABLO other 2.68526193818845e-11 0.00516184375476391 1 3.80417723512609 -5.32379600920897 6.59319052425666e-14 102.074879150538 13.6029030836195 7.50390402130083 4.9613683901297e-12 -45.6005458024214 26.641501222439 -1.7116357453616 0.0890169505863524 VPS33B other 8.64631005351018e-10 1 6.65815637955405e-08 7.50390402130083 -1.7116357453616 0.057414068007698 49.0033112582782 28.2973284646479 1.73172924502391 0.085508865024218 106.133813790417 45.0381726276092 2.35653019646172 0.0198226075295473 TBX1 other 1 1 1 1.73172924502391 2.35653019646172 0.0919242250611668 -6.79373381404555 24.3996910964778 -0.27843523867506 0.781066908603073 200.179454628548 94.3056490681696 2.12266663351044 0.0354460804764516 ADAP2 other 1 1 1 -0.27843523867506 2.12266663351044 0.0598772822491912 319.976862828934 270.225692882127 1.18410969518175 0.238267870630602 -726.927158238425 497.677933605159 -1.46063771196885 0.146234554410639 UQCR10 other 1 1 1 1.18410969518175 -1.46063771196885 2.96412020429088e-05 1134.60887096774 344.526556043852 3.2932406836683 0.00123366757279776 -1045.80435217275 729.06953204706 -1.4344370546337 0.153515346930109 EIF3C other 0.23253523002662 1 1 3.2932406836683 -1.4344370546337 0.627463408728002 4.36577404340194 13.7432096415498 0.317667717896329 0.751203647516867 20.5450323755204 21.9095824884067 0.937719027114811 0.349980999591841 CLDN5 other 1 1 1 0.317667717896329 0.937719027114811 0.00404425306645605 967.430987707671 296.142400324779 3.26677634356542 0.00135017102014802 246.241404974547 544.896742099579 0.451904711387587 0.651994781238643 NIPSNAP1 other 1 1 1 3.26677634356542 0.451904711387587 0.254382668871898 2.59558660883448 2.56199908509007 1.01310988904714 0.312596766433523 -10.077448330913 9.38955628413275 -1.07326140085476 0.284832725524112 CNTN2 other 1 1 1 1.01310988904714 -1.07326140085476 9.05853848786782e-06 150.787647814267 38.2209869850135 3.94515316607054 0.000121475493200993 -245.528862351352 138.215254062809 -1.77642376752263 0.0776635549115309 LRTOMT other 0.0751586938338393 1 1 3.94515316607054 -1.77642376752263 0.601336847102084 22.0342363291664 27.2486450144577 0.80863603740573 0.420013796002816 -74.76381894662 177.924721255025 -0.420199162990166 0.67494530732512 KCNQ3 other 1 1 1 0.80863603740573 -0.420199162990166 0.0722186199888386 -252.233024277956 122.531816598314 -2.05851044471847 0.0412712621313515 -466.681347389782 227.611417746987 -2.05034243013479 0.0420719473152169 ADRA2C other 1 1 1 -2.05851044471847 -2.05034243013479 6.06339333584122e-07 201.618094648933 43.071612482029 4.68099713548118 6.39638785431262e-06 -113.933665326322 145.182938757484 -0.78475932710412 0.433849032423901 NR2C2AP essential 0.00563531776633083 1 0.0660491009836321 4.68099713548118 -0.78475932710412 0.410170415670262 16.2714062624071 18.1588126432805 0.896061134725578 0.371970446813129 -14.9477356343135 40.0902202749063 -0.372852419662801 0.709900023443939 C1QTNF12 other 1 1 1 0.896061134725578 -0.372852419662801 0.000828935302079185 232.732496709734 86.1079076717755 2.70280050929654 0.00766364881454532 -87.4623797430811 139.323252340319 -0.627765848657052 0.531105560563149 CRELD2 other 1 1 1 2.70280050929654 -0.627765848657052 0.00509402274893033 16.005600167586 18.5242035772635 0.864037155542341 0.389111488867155 -62.5689314060936 30.7693770424086 -2.03348060377877 0.0439782536949508 SCFD2 other 1 1 1 0.864037155542341 -2.03348060377877 0.0268581398486589 46.8146048682895 48.6816283371234 0.961648294590628 0.337763699475514 -190.889421473825 107.882589917445 -1.7694182316155 0.0788426758825723 UBE2F other 1 1 1 0.961648294590628 -1.7694182316155 0.120729339399014 47.2560451246014 32.2975584512024 1.46314605161252 0.145426530071224 -58.984026076101 78.6953620010193 -0.749523537045767 0.454663329333732 KCNJ12 other 1 1 1 1.46314605161252 -0.749523537045767 6.12265658274622e-10 258.94291023442 38.1425679391354 6.78881691048223 2.3041171563428e-10 -54.6735086716217 141.900891997311 -0.385293622203995 0.700551538365054 PPP1R2 essential 6.98778795788826e-06 1 2.96839413251643e-06 6.78881691048223 -0.385293622203995 0.00148281935957786 15.4314953045991 6.09571700483133 2.53153079323866 0.0128982474527844 -15.7175535757284 10.2192333131238 -1.53803647437459 0.127166765287403 GOLGA6L4 other 1 1 1 2.53153079323866 -1.53803647437459 0.00331419658684249 138.636617927527 58.7388164889418 2.3602215062271 0.0196642041547826 -103.242191142191 124.347195543159 -0.830273579482199 0.407818181412036 PGP other 1 1 1 2.3602215062271 -0.830273579482199 0.135801491199495 38.9459565002126 24.3054120403252 1.60235738590225 0.111125769150745 -1.23442326869039 35.7297824044091 -0.0345488605197344 0.97248422054158 C22orf46 other 1 1 1 1.60235738590225 -0.0345488605197344 3.5692646477306e-11 71.3896212427551 16.697682919151 4.27542082266256 3.35582372318833e-05 -139.457190996091 39.5608916959073 -3.52512759489995 0.000559627166813126 SNRNP35 essential 4.3006069740506e-07 1 0.323266499254732 4.27542082266256 -3.52512759489995 3.47253813868306e-08 106.907483158462 21.1549225803401 5.05355114170041 1.22223946413662e-06 -222.157952620451 93.8558485067844 -2.36701235090738 0.0191835921127045 CMSS1 other 0.0003572894490891 1 0.0132820762567726 5.05355114170041 -2.36701235090738 1.17116775167155e-10 25.8097504181728 3.70198067365563 6.97187605592933 1.15672848317633e-10 8.36043195094797 7.01745671029205 1.19137634845488 0.23553618212977 PCDH9 other 1.38291488117377e-06 1 1.50386270097755e-06 6.97187605592933 1.19137634845488 0.000149365367188505 42.335997978545 17.3570665865246 2.4391217126178 0.0158667722747051 -44.8063767716446 26.0966798188581 -1.71693782820857 0.0880141171781958 ACOT1 other 1 1 1 2.4391217126178 -1.71693782820857 0.000210922072857018 177.043135432459 52.9196170814716 3.34551051569203 0.00103477617832279 -179.255149663647 153.195360256138 -1.1701082158359 0.243788806711912 OAF other 1 1 1 3.34551051569203 -1.1701082158359 0.0778309797433849 101.077763224642 44.7199161444049 2.26024044629806 0.0252081073965061 34.6711272119906 82.8752609003857 0.418353159137135 0.676271745600808 ALDH1A3 other 1 1 1 2.26024044629806 0.418353159137135 0.0372177836623523 20.5309579941836 9.27917965294544 2.21258330607562 0.0283979843535857 -10.288585637831 23.6331633402305 -0.435345259951587 0.663921369389486 POU6F1 other 1 1 1 2.21258330607562 -0.435345259951587 7.8892353398942e-10 282.426017656177 46.0703404088 6.13032191970151 7.22276991905479e-09 -116.291610820818 85.2605555043069 -1.3639555845369 0.174597895850104 TM2D3 other 8.95349318724592e-06 1 8.84717087385022e-05 6.13032191970151 -1.3639555845369 0.000321699380653117 124.779189061333 33.4953074851956 3.72527373025262 0.000276270840812972 53.6175370901277 56.9807371330682 0.94097654379082 0.348239932897958 TSSC4 other 1 1 1 3.72527373025262 0.94097654379082 0.061342149670884 -196.946306617475 879.918168342062 -0.22382343461388 0.823189434125452 -6298.10915299475 2700.82060068808 -2.33192428678536 0.0209915603181077 TACSTD2 other 1 1 1 -0.22382343461388 -2.33192428678536 0.39001135951631 15.2506904475786 14.8242162192999 1.0287687539071 0.305211970830495 -9.9908080871967 26.9117801084717 -0.371242929561974 0.710970164396058 PRKD1 other 1 1 1 1.0287687539071 -0.371242929561974 4.91648127933701e-05 16.4649942769936 7.11721123477702 2.31340531197672 0.0220146620313257 -15.2156784065045 10.7194158494155 -1.41945033388495 0.157775736259663 CCSER1 other 0.374586708672687 1 1 2.31340531197672 -1.41945033388495 0.059375754918068 61.7477709096875 37.0970900682569 1.66449095592335 0.0981888241439201 -112.666967525482 114.69293518779 -0.98233572400086 0.327582060390196 MROH7 other 1 1 1 1.66449095592335 -0.98233572400086 0.24449192919692 279.717044438276 191.569418691877 1.46013411925719 0.14631701472685 -89.442392656326 320.275984205337 -0.279266623372492 0.780419841866951 SLIT3 other 1 1 1 1.46013411925719 -0.279266623372492 0.00942380214925632 56.4655736093008 85.3185802351255 0.661820361446357 0.509056561162382 -241.157788648264 125.217668220528 -1.92590863633994 0.0559228253488349 EFNA5 other 1 1 1 0.661820361446357 -1.92590863633994 0.837414098032877 1.5398664140478 3.09907887278908 0.496878742767191 0.619997205481462 -0.719524417535048 8.89935119919983 -0.0808513341511618 0.935667245156597 HIST1H1B other 1 1 1 0.496878742767191 -0.0808513341511618 0.0365331840564724 229.993534232806 165.326943482816 1.39114369011916 0.166255639090899 -314.450632079485 285.618399313375 -1.10094669263403 0.272695237372904 PKP3 other 1 1 1 1.39114369011916 -1.10094669263403 0.0938925667841305 332.349335899159 256.773416061584 1.29432922222544 0.197514695436539 -1183.84943501869 881.505335787873 -1.34298612493432 0.181278378750754 CSF1 other 1 1 1 1.29432922222544 -1.34298612493432 2.53530519903529e-14 25.866947595579 2.93219851817914 8.82169042621374 2.90199047842272e-15 -3.0310941646496 17.333597866216 -0.174868148438896 0.861422235314211 ACTRT3 other 3.3552229004033e-10 1 4.05553169359575e-11 8.82169042621374 -0.174868148438896 5.22326985709636e-11 317.123917578806 44.6315346428491 7.10537784811789 4.80234114071834e-11 106.372758709382 90.2801958639718 1.17825130629598 0.240600270172885 PLA2G6 other 6.25382099990147e-07 1 6.31141206877226e-07 7.10537784811789 1.17825130629598 8.41983302052039e-07 324.853674304298 73.0834670047276 4.44496802927103 1.66644796495528e-05 -196.546955886635 203.280180296014 -0.966877122995587 0.335111659164943 MAML2 other 0.00772940671283772 1 0.165611598757256 4.44496802927103 -0.966877122995587 1.86196714093496e-11 140.751955841099 19.227600223733 7.3203080053311 2.05801519987896e-11 -2.05321275760916 71.2164653853279 -0.0288305906014842 0.977042597568893 SS18L1 other 2.26768978094469e-07 1 2.72666433831964e-07 7.3203080053311 -0.0288305906014842 0.436356713409401 4.89593549888368 22.4480188500056 0.218101006222314 0.827641035787656 -77.5263554800958 68.6412840936228 -1.12944209164785 0.260479040249144 KCND2 other 1 1 1 0.218101006222314 -1.12944209164785 1.51952406084868e-07 320.022234513274 55.2216098221817 5.7952355163816 6.0710508355412e-08 43.8102876106195 229.864181352915 0.190592058983547 0.849181263385004 TOP1MT other 0.00148989334166213 1 0.000713885598218179 5.7952355163816 0.190592058983547 1.53427850387266e-10 856.651397761054 119.39236021788 7.17509391888847 3.03195300987234e-11 217.689978495984 488.369980927507 0.445748074200936 0.656417684853973 COPB2 essential 1.80201010279843e-06 1 4.00369394953642e-07 7.17509391888847 0.445748074200936 1.29775013021826e-16 404.956302818683 45.0818677162503 8.98268690568719 1.46630399425606e-15 59.1498861393654 81.0840644054459 0.729488421345005 0.466904537700786 THAP7 other 1.78220025382873e-12 1 2.05370537435503e-11 8.98268690568719 0.729488421345005 3.79555600166039e-05 169.347539305301 45.6381082593134 3.71066080002872 0.000289417545698002 -62.4683782615919 102.465072287628 -0.609655337832954 0.543000414862837 KNTC1 other 0.293130790008232 1 1 3.71066080002872 -0.609655337832954 0.00756946394998254 16.1312907822696 5.21434686966994 3.09363592132693 0.00235104743172271 21.8139203480087 20.5247767526953 1.06280914091522 0.28954313038421 CCR10 other 1 1 1 3.09363592132693 1.06280914091522 0.0620718232183152 21.1330633063307 10.0189687615044 2.10930523982963 0.0365251726377258 9.09683468346836 22.2187822610484 0.409420938402008 0.682795996820161 NCMAP other 1 1 1 2.10930523982963 0.409420938402008 2.4993387459086e-13 140.269339060293 19.9800542263223 7.02046838669229 9.56815920787212e-11 -0.765555377057865 41.1311999200099 -0.0186125223321149 0.985177491564948 WDR27 other 3.22789599034096e-09 1 1.24749659752237e-06 7.02046838669229 -0.0186125223321149 7.66772366084394e-10 131.940971625107 28.9904868913766 4.55118163828956 1.14160096723632e-05 -90.5448839208943 45.7919701424475 -1.97730920157468 0.0499568364299931 TXNRD2 other 8.70823376162046e-06 1 0.115278865671524 4.55118163828956 -1.97730920157468 0.55803287220584 -2.13962178092765 4.37506497343529 -0.489049144165652 0.625507229318247 -9.61424397649925 9.0638435545504 -1.06072483694542 0.290486526500108 POU3F2 other 1 1 1 -0.489049144165652 -1.06072483694542 0.00115690413234321 435.486651184393 118.375394057359 3.67886125872895 0.000331718174052922 924.220418021364 528.625370252875 1.74834669319645 0.0825651616159978 PTP4A3 other 1 1 1 3.67886125872895 1.74834669319645 0.412962498871719 -6.49380112145688 7.32105438897772 -0.887003534795982 0.376525884613183 7.83162714131384 13.5550356508021 0.57776514522486 0.564306639069344 TMEM255B other 1 1 1 -0.887003534795982 0.57776514522486 2.83631287574629e-07 147.057499567642 28.8146072857097 5.10357465952949 1.02910081594865e-06 -41.7156192609551 52.1555693695897 -0.799830579268456 0.425117345552708 HDDC3 other 0.00271179393145354 1 0.0112408682126071 5.10357465952949 -0.799830579268456 1.55550444234596e-17 118.841767731285 16.0092384517088 7.42332423180314 7.58314658209818e-12 -6.08975173026863 26.9792481897184 -0.225719845395447 0.821722537106628 ZFP1 other 2.15888461553196e-13 1 1.0134117092316e-07 7.42332423180314 -0.225719845395447 0.821328755082083 -4.60491166350949 36.3410483901426 -0.126713781453772 0.899337772919857 -36.8006146828005 62.7827010643386 -0.586158512757963 0.558655893942138 CEND1 other 1 1 1 -0.126713781453772 -0.586158512757963 0.180705686337903 75.3527759078497 44.8452410907036 1.6802847766041 0.0949559327328916 23.4356277347692 77.5250840200855 0.302297353572651 0.762838650901181 DUSP8 other 1 1 1 1.6802847766041 0.302297353572651 0.617554953538912 -227.620483985391 235.43282771209 -0.966817101070321 0.335113020131134 -186.088953992493 952.394293527672 -0.195390664619817 0.845338169785368 SOCS3 other 1 1 1 -0.966817101070321 -0.195390664619817 0.257242525638458 38.2642478462558 23.1508947665256 1.65281939346823 0.100561503040427 33.5706468261141 42.0243166219183 0.798838613561293 0.42570877673027 SLITRK6 other 1 1 1 1.65281939346823 0.798838613561293 0.776642423359287 4.99414530337521 9.85698711157837 0.506660427455455 0.613157410277481 -13.1461843016925 42.5241975554381 -0.309145969998706 0.75765122397938 LPAR5 other 1 1 1 0.506660427455455 -0.309145969998706 8.15878936746009e-16 705.987987424146 92.9314370948178 7.5968693640649 3.02893138756779e-12 -813.654682054908 284.462016203843 -2.86032804278463 0.00483603046911077 XPOT other 1.10894265082517e-11 1 4.08087925847008e-08 7.5968693640649 -2.86032804278463 0.0124954022095003 -457.21355605924 260.755929347274 -1.75341576010847 0.0815598060500278 -1138.36212624585 380.835967181565 -2.98911401323376 0.00326722204234733 TMEM173 other 1 1 1 -1.75341576010847 -2.98911401323376 0.0436175265047491 75.7658522333325 36.289463358381 2.08781958237017 0.0384393152355997 -84.5321579794263 112.945377107269 -0.748433978835119 0.455325327933037 PDE4B other 1 1 1 2.08781958237017 -0.748433978835119 0.691197825346766 1.18353887268002 6.54490629454643 0.180833585603237 0.856742300316154 -15.6281217054454 21.282145750465 -0.734330169931474 0.463893894121133 FAM19A3 other 1 1 1 0.180833585603237 -0.734330169931474 1.1426414378254e-07 267.877477178048 46.1897291367561 5.79950309699653 3.61971586233247e-08 192.694227377278 101.988454352804 1.88937295500822 0.0607093387958213 SNN other 0.00113121502344715 1 0.000430058441603721 5.79950309699653 1.88937295500822 0.00436622905381108 33.1841422393081 12.4711604877486 2.66087043558676 0.00867230189132289 -42.6919269581933 41.3387785529347 -1.03273314917919 0.303448216460632 NELL2 other 1 1 1 2.66087043558676 -1.03273314917919 1.85704583171567e-06 19.8302013422818 3.73025222867214 5.31604838671748 3.77401280450467e-07 41.7389261744965 19.3392545694832 2.1582489658293 0.0324995250710822 KRBA2 other 0.0165351360855963 1 0.00423444236665424 5.31604838671748 2.1582489658293 1.92347919414373e-09 146.040886558779 23.4981477824547 6.21499566309745 4.59129582111945e-09 26.7150399686811 79.0330861798943 0.338023494462466 0.735805837871033 ZNF93 other 2.13967825556549e-05 1 5.66336339535084e-05 6.21499566309745 0.338023494462466 1.66982479492833e-06 2072.24996267728 385.602651479673 5.37405527354503 2.71642472646523e-07 -197.609687318558 1701.06214968675 -0.116168411221746 0.907666592007441 SEPT9 other 0.0149299034914542 1 0.00307580771777658 5.37405527354503 -0.116168411221746 1.35394055591131e-06 55.8618789870483 22.0725195729868 2.53083381814799 0.0123761435887075 -59.3191378310457 40.6436741551458 -1.45949250563843 0.146453303385201 CDCA2 other 0.0122071280520964 1 1 2.53083381814799 -1.45949250563843 0.0159881739754052 -6.31660690099578 21.7939838315742 -0.289832595536964 0.772331664668993 -84.9184929504352 33.491558341808 -2.5355193115762 0.0122184443152677 OR7E14P other 1 1 1 -0.289832595536964 -2.5355193115762 5.49853814140146e-11 203.249738475972 39.1163698285874 5.19602763156798 6.45547968242304e-07 -79.7039112854794 83.7011854646257 -0.952243517735653 0.342485275619509 ZBTB40 other 6.57845103237271e-07 1 0.00713717833688691 5.19602763156798 -0.952243517735653 5.35510359555066e-09 2845.10241715426 450.999874039519 6.30843284205653 3.04350237915351e-09 1572.76628726974 966.45762432029 1.62735152343163 0.105775316762491 CLDN6 other 5.80439678721737e-05 1 3.77698645252951e-05 6.30843284205653 1.62735152343163 2.02124930716122e-19 282.72245180317 26.9347737860357 10.4965593566539 9.4185860595131e-20 111.438971922351 44.8220428941656 2.48625374317459 0.0139841276346834 EIF4ENIF1 other 2.84652539927515e-15 1 1.34770547925573e-15 10.4965593566539 2.48625374317459 0.399940040033155 -22.7168311179973 28.7264734047897 -0.790797770331586 0.430609271619736 -60.6600614314062 44.9434943711294 -1.34969615247302 0.179633180570664 LRRC26 other 1 1 1 -0.790797770331586 -1.34969615247302 1.14604413627833e-07 29.8711441805459 13.1289783224899 2.27520706080965 0.02442342337255 -82.2000098551296 22.9310189847554 -3.58466450661334 0.000466179567822854 SERINC4 other 0.00113446909050192 1 1 2.27520706080965 -3.58466450661334 2.15063253032618e-07 57.8302080703906 17.4960204144075 3.30533496764607 0.00117548991469925 -66.6981897515414 31.3013315713304 -2.13084192918591 0.0346594969241086 RNLS other 0.00208159722610271 1 1 3.30533496764607 -2.13084192918591 0.00952647073283039 -31.3498210547639 12.6452301996706 -2.47918152218223 0.0142605237031465 12.3366646408715 26.4495842894828 0.466421872867656 0.641581332890672 APOBR other 1 1 1 -2.47918152218223 0.466421872867656 0.00951044656295891 53.9612859833201 49.7209836709784 1.08528194736454 0.279610349751091 -332.553435566317 143.172574957402 -2.32274536981165 0.0215936739351843 FAM110C other 1 1 1 1.08528194736454 -2.32274536981165 0.0775198570534474 66.1276132280966 111.92076336145 0.590843121883796 0.55555176086035 -693.629890520241 354.963957856457 -1.95408540830147 0.0526288267094323 ATL3 other 1 1 1 0.590843121883796 -1.95408540830147 3.71680343480426e-05 -97.6312509412717 71.8982482315475 -1.35790861867526 0.176453502302239 -650.533315643399 144.974041970014 -4.48723996933156 1.39359416828114e-05 NDUFA12 other 0.287569081750806 0.202085090342448 1 -1.35790861867526 -4.48723996933156 9.16062378568699e-09 26.1201942252667 4.72329380587969 5.53008034197481 1.59918156837878e-07 1.99689008352843 9.74896154265657 0.204831055573565 0.83801262779888 TCTE3 other 9.79087470214225e-05 1 0.00183713978575354 5.53008034197481 0.204831055573565 1.03072430872452e-05 209.322115540914 92.8308377569673 2.25487694174346 0.0255600261775797 -465.876082315587 164.96359601827 -2.82411449289691 0.00537292050922459 UBE2G2 other 0.085096598928296 1 1 2.25487694174346 -2.82411449289691 1.08366783718073e-12 344.871568549667 42.4055424911656 8.13270030967094 1.3375713266749e-13 199.469703180649 76.8451600822735 2.59573541088455 0.0103580190112329 OSBP2 other 1.37441591789632e-08 1 1.83675294578997e-09 8.13270030967094 2.59573541088455 0.604091341927339 3.73167379174579 4.35987215260413 0.85591358212577 0.393401732461025 6.8786998963272 8.21479197717933 0.837355336012915 0.403716209883173 B3GALT5-AS1 other 1 1 1 0.85591358212577 0.837355336012915 0.136557565643924 8.80557868442971 4.74885043589242 1.85425479351298 0.0657770953908661 23.2102233645876 20.1407126107267 1.15240328449085 0.251091753537963 TUSC5 other 1 1 1 1.85425479351298 1.15240328449085 4.58622832449605e-06 530.531456985426 182.468414387489 2.90752489282224 0.00419636475990782 -389.716000793547 368.021251752728 -1.05894971808692 0.291324945619932 ZBTB7C other 0.0391443413154353 1 1 2.90752489282224 -1.05894971808692 0.846962103594477 2.22182659891536 27.7575419483604 0.080044068853388 0.936305460118234 -17.0078479992182 40.3486778518388 -0.421521816939613 0.673958072631542 PRR16 other 1 1 1 0.080044068853388 -0.421521816939613 0.0666151663426781 344.754367250227 183.294819913416 1.88087348793098 0.0618893418716958 -110.379293499039 295.959718755157 -0.372953772098811 0.709699028417999 TMED9 other 1 1 1 1.88087348793098 -0.372953772098811 1.57811155395685e-18 111.80365170922 11.7618599267057 9.50560986152936 3.98745469718459e-17 31.8305623886674 26.8289224284472 1.1864271654428 0.237292695376023 TMEM186 other 2.20935617553959e-14 1 5.64105216010704e-13 9.50560986152936 1.1864271654428 7.27831448038975e-06 68.9752652089199 21.269824883571 3.24286944469378 0.00145093900414345 -35.8478320769942 39.3940070066825 -0.909981867823531 0.364254113515358 SDR42E1 other 0.0608831006284602 1 1 3.24286944469378 -0.909981867823531 8.04987373508684e-05 198.399335178242 49.5619319686142 4.00305894661009 9.74632782673219e-05 -59.8630183344522 142.060928649089 -0.421389743849434 0.674065801603868 RBM33 other 0.597944621042251 1 0.893153482041738 4.00305894661009 -0.421389743849434 1.8699441986166e-15 570.777772507352 67.3827801760931 8.47067709310486 2.40308747973612e-14 -1.51696549979398 137.696563013496 -0.0110167274084053 0.991225140509123 BTBD6 other 2.52797756210978e-11 1 3.32827615943453e-10 8.47067709310486 -0.0110167274084053 0.0427501311470181 549.719538082235 228.875078406528 2.40183222179316 0.0175284466712844 -436.585849484239 941.857337564356 -0.463537132505917 0.643646864773175 H1FX other 1 1 1 2.40183222179316 -0.463537132505917 0.106695288786114 18.2326185298354 19.042717410744 0.957458861388577 0.339798453154876 -87.266434821972 55.8840545281231 -1.56156233757262 0.120391872052571 RBM43 other 1 1 1 0.957458861388577 -1.56156233757262 0.000440066134117846 61.3845086289956 228.931557972149 0.268134761204322 0.788956754054543 -1383.99513445556 405.158796876917 -3.41593258032111 0.000814199619050683 SUMO3 other 1 1 1 0.268134761204322 -3.41593258032111 4.01677849891521e-05 51.7068824374387 13.8765882870488 3.72619561579825 0.000273566910565854 -56.2837551881412 42.3553688362117 -1.32884582839523 0.18589020957111 IMMP2L other 0.30889026656658 1 1 3.72619561579825 -1.32884582839523 5.63203844108436e-06 32.5273004081932 7.77269447981891 4.18481653854366 4.81079750331056e-05 -0.849637774427253 17.3553641859342 -0.0489553411455259 0.961019153862026 CLCNKB other 0.0476357811346915 1 0.456159819263907 4.18481653854366 -0.0489553411455259 0.000242680552014196 254.557358003027 62.3028891563279 4.08580342661641 7.24086727443464e-05 105.565254490585 128.630362908137 0.820686905516822 0.413171801481869 JAG2 other 1 1 0.672242117758512 4.08580342661641 0.820686905516822 0.038350880599268 111.440551719303 51.8984700966251 2.14728009345598 0.0333157320586453 338.28648042343 208.639945117116 1.62138884878223 0.106953717372036 FMNL1 other 1 1 1 2.14728009345598 1.62138884878223 7.2393300722005e-08 24.0378629348679 4.32532987680646 5.55746350440578 1.18682077695181e-07 8.39799404917609 7.96021987889693 1.05499523592806 0.293090606347712 NUTM2A other 0.00072900053827059 1 0.0013742197776325 5.55746350440578 1.05499523592806 2.15646114818445e-05 222.648574287144 57.7625789358727 3.8545469816077 0.000170258771739235 -363.036685009172 196.724061586904 -1.84541068378053 0.0669107779336418 PTRHD1 other 0.172020905790673 1 1 3.8545469816077 -1.84541068378053 0.190779308937167 323.570750519133 188.52113807863 1.71636323553371 0.0886129855442307 80.4983989739475 294.01454929051 0.273790528965995 0.784704839551884 LCN12 other 1 1 1 1.71636323553371 0.273790528965995 0.0238770521748317 878.782787813583 458.105094725607 1.91829952980538 0.0569233637526406 -559.729896936406 743.032083452798 -0.753305152498119 0.452416668150214 WT1 ts 1 1 1 1.91829952980538 -0.753305152498119 3.98792763634316e-16 229.417491039426 34.613237289354 6.62802756996059 5.57208329927009e-10 -9.32781362007179 55.7838226657825 -0.167213596600532 0.86742423848612 ZFP90 other 5.44471760189932e-12 1 7.09103320665111e-06 6.62802756996059 -0.167213596600532 1.26330310923279e-08 95.7133175111938 14.9687755826695 6.39419817490007 1.93498352211262e-09 102.191110784882 30.0138614761644 3.40479717566622 0.000849622414691481 FAM227A other 0.000133960661703045 1 2.42027738945847e-05 6.39419817490007 3.40479717566622 0.773684303777781 -67.9388690756764 125.915172770302 -0.53956062308402 0.59029482832123 -150.565004135576 219.732499765357 -0.685219547842753 0.49425593620359 MUC6 other 1 1 1 -0.53956062308402 -0.685219547842753 2.16898849505101e-08 80.1659834429409 34.1050740781057 2.35055884233967 0.020064739709209 -239.003458637539 66.1365989189843 -3.61378514384013 0.000412842946962633 NOC4L essential 0.000226507468538177 1 1 2.35055884233967 -3.61378514384013 0.133871770581715 234.332257889232 119.976267200643 1.95315509772733 0.0527674138006277 123.741329656447 193.705008885379 0.638813267496186 0.523973460030468 USP18 other 1 1 1 1.95315509772733 0.638813267496186 0.00329972944883368 73.5668229107126 116.151718542998 0.633368355057778 0.527426560268227 -404.457070995771 172.713911627635 -2.34177471394294 0.0204645945604366 NDUFA6 other 1 1 1 0.633368355057778 -2.34177471394294 0.207536957223145 -65.24745282262 44.2339433554927 -1.47505394891541 0.14225288244896 -140.78383534047 83.9100679996453 -1.67779431832978 0.0954288546628177 SORCS2 other 1 1 1 -1.47505394891541 -1.67779431832978 1.53701043195403e-10 139.013825435217 20.0518715639744 6.93271074431638 1.18861278369379e-10 34.9008181791038 41.5422577908949 0.840128101721838 0.402191710430581 TMEM121 other 1.80506505128681e-06 1 1.54460231241008e-06 6.93271074431638 0.840128101721838 0.0926404853133856 22.0203776805718 10.787722421391 2.0412443721121 0.0429226506028913 46.7347700842847 45.7628536508398 1.02123810811407 0.308732927278097 TMEM106A other 1 1 1 2.0412443721121 1.02123810811407 5.0191006695189e-09 604.082742237407 113.179484826138 5.33738727619566 3.58624265048284e-07 -289.996613754837 231.522876033782 -1.25256138280056 0.212395735783067 SIVA1 other 5.44973950696363e-05 1 0.00403021949061262 5.33738727619566 -1.25256138280056 0.00165844603026643 88.3736903376022 68.7175266529903 1.28604294482064 0.200383671134273 -369.683326476844 157.074014269286 -2.35356133346833 0.019874415316602 BRI3BP other 1 1 1 1.28604294482064 -2.35356133346833 0.620232844714007 -13.0241909898477 13.3659820292782 -0.974428288270788 0.331372048733454 -13.0369870981386 30.3772318847232 -0.429169686942244 0.668399531648645 ROBO2 other 1 1 1 -0.974428288270788 -0.429169686942244 1.19101666444151e-07 376.724659725271 70.7242810673258 5.32666651452631 3.73694190359908e-07 -73.8627454055076 163.658838086174 -0.451321457913659 0.652432153601407 AP3M1 other 0.00117743907446688 1 0.00419434359259961 5.32666651452631 -0.451321457913659 0.00034181128277452 16.8807744678024 6.36099292275105 2.65379551161357 0.00881719030257749 -34.885291089635 21.0683917729817 -1.65581177080504 0.0998505133341195 CA13 other 1 1 1 2.65379551161357 -1.65581177080504 2.18918309560602e-16 173.29186222832 19.6734937494692 8.80839287800599 3.01465647300606e-15 -26.2641345945556 74.9782964561122 -0.350289828336245 0.72661589245914 UBOX5 other 2.99808624943244e-12 1 4.21237948973136e-11 8.80839287800599 -0.350289828336245 0.00425497427624391 51.1694633862133 50.4626502737553 1.01400665856081 0.312234420348565 -244.122080838535 102.142242283687 -2.39002077280149 0.0181058428266437 MAFF other 1 1 1 1.01400665856081 -2.39002077280149 1.19900282900459e-16 463.563840174791 50.3429913988507 9.2081107477728 3.42653696247878e-16 83.417870286226 103.443417077759 0.806410621794527 0.42132676300391 BRF1 essential 1.64742988705231e-12 1 4.82148015990389e-12 9.2081107477728 0.806410621794527 8.17812849861631e-08 975.617670681281 178.182475356787 5.47538510017742 1.73756165374616e-07 -190.782882328418 318.99178335716 -0.598080866913137 0.550664527493765 SEMA4B other 0.000819693819416312 1 0.00199159316752385 5.47538510017742 -0.598080866913137 0.028575085175471 17.2165377751339 7.45461447104487 2.30951417300065 0.0222098272877222 -2.72738166057619 16.6038844475631 -0.164261662335074 0.869735107870954 MROH2A other 1 1 1 2.30951417300065 -0.164261662335074 0.00794545503963373 347.097594299524 154.382775340979 2.24829223035343 0.0259769425438637 -376.800154857155 276.384289347404 -1.36331973046244 0.174771562518663 CIB1 other 1 1 1 2.24829223035343 -1.36331973046244 7.86022673519288e-08 54.2680263242159 12.3572432710836 4.3915965020455 2.10612381126092e-05 -27.7964431418788 25.0707080851787 -1.10872190156892 0.269312934097997 ANKS1B other 0.000788616548341901 1 0.207326827980525 4.3915965020455 -1.10872190156892 0.33176268573811 -28.365394726199 19.0257785475042 -1.49089271986296 0.138061993856331 -37.4101704683327 62.8455498702064 -0.595271591156338 0.552547157581809 SLC24A3 other 1 1 1 -1.49089271986296 -0.595271591156338 0.0210790912010358 7.48642080320797 11.3535017060716 0.6593931103392 0.510621858057719 -83.9721732790569 35.4883435094508 -2.3661902747502 0.0192083593405409 EFCAB10 other 1 1 1 0.6593931103392 -2.3661902747502 0.958914000952032 7.41790593587845 31.800886579078 0.233260978980339 0.815866521089755 13.1661541405873 51.869706667685 0.253831282003179 0.799962300216028 FLRT2 other 1 1 1 0.233260978980339 0.253831282003179 0.00107518154605984 -78.860395288217 56.4905575389457 -1.39599251138297 0.164752362717926 -349.077775211447 92.5637438263886 -3.77121495718856 0.000232144445394604 RPS27L other 1 1 1 -1.39599251138297 -3.77121495718856 0.461466461807166 27.940769400553 40.6490444291601 0.687365958854112 0.492899607327374 -121.208079614651 161.447073722572 -0.750760461740747 0.453957497476034 MANEAL other 1 1 1 0.687365958854112 -0.750760461740747 1.20637362975859e-09 79.5128582148579 13.0654822039712 6.08571937671694 9.97038233258107e-09 -8.10210179758112 26.8862351884372 -0.30134757584303 0.763584183825412 ADSSL1 other 1.35656714666353e-05 1 0.000121359493752177 6.08571937671694 -0.30134757584303 0.0923606320047354 131.547048362779 104.514432260726 1.25864960003434 0.210125446214607 -151.824100204895 180.558862449166 -0.840856539222157 0.401775679608247 ANO9 other 1 1 1 1.25864960003434 -0.840856539222157 1.17235596270688e-07 206.082660709138 51.5677355970613 3.99634884726027 9.94584723735224e-05 -506.304093398673 167.408338662202 -3.02436603483832 0.00292000705355324 FAF1 other 0.00115969451830965 1 0.910243939162477 3.99634884726027 -3.02436603483832 0.00930250522974843 193.948103180056 79.2029817155433 2.4487474963584 0.0154501627714592 -417.072620809703 294.991772391565 -1.41384492668524 0.159412779729466 FAM43A other 1 1 1 2.4487474963584 -1.41384492668524 1.7531462386316e-05 75.0484928862066 45.7933886690775 1.63884995339696 0.103285900295174 -193.510578215642 66.6755462463525 -2.90227210888772 0.00424849939909492 NSMCE3 other 0.141058146360298 1 1 1.63884995339696 -2.90227210888772 3.68306642700769e-05 1069.00215734216 238.961884416737 4.4735258091532 1.94054005625185e-05 -140.43649024402 918.738896700789 -0.152857891124813 0.878800941372762 HSF1 essential 0.285069341450395 1 0.191589519753746 4.4735258091532 -0.152857891124813 1.90168362419853e-06 129.419335818955 37.6222727832596 3.43996590967628 0.00077442579013843 -118.983412815399 77.65303315554 -1.53224424057041 0.127802260861014 C6orf120 other 0.016905967419125 1 1 3.43996590967628 -1.53224424057041 0.0557617773477478 38.1948420976907 43.4757246624199 0.878532615482913 0.381041390996622 -99.2267462772465 63.1870801566561 -1.57036448006838 0.11840969091532 PURA other 1 1 1 0.878532615482913 -1.57036448006838 1.44662078825621e-08 120.135959339263 19.0903326256243 6.29302598834809 3.16297688035747e-09 51.9729493152621 32.8128524204905 1.58392049094783 0.115290210137116 INPP5J other 0.000152821020071386 1 3.92304022470737e-05 6.29302598834809 1.58392049094783 0.00848047521229902 6.02115585097627 2.21935807124604 2.71301685338037 0.00741671692669033 -3.30372637701153 7.13530695355399 -0.463011107793477 0.644001658112687 MIXL1 other 1 1 1 2.71301685338037 -0.463011107793477 5.80580242552511e-08 68.0823513101347 11.3688380857095 5.98850566758565 1.55514762596365e-08 33.1658394565375 54.0732212767516 0.61335053975778 0.540592452159559 MFSD6L other 0.000588127785705694 1 0.000187659664025033 5.98850566758565 0.61335053975778 1.13831048716099e-09 64.7388749517562 9.42834708432935 6.86640769296214 1.54796976006303e-10 24.648234272482 36.7461732795279 0.670770098561909 0.503378309961907 LRRC37B other 1.28128228434841e-05 1 2.00570441811367e-06 6.86640769296214 0.670770098561909 7.83281034678567e-10 128.267060956539 28.1837408333834 4.55110135005953 1.10486938131914e-05 -104.645699974878 54.6539426733187 -1.91469626629452 0.0574606244814882 DDX51 essential 8.89258958670578e-06 1 0.111746489226618 4.55110135005953 -1.91469626629452 0.302199506455766 7.58375634517766 10.8501084197812 0.698956734049905 0.485714322194222 -21.6704453354946 23.7131920996352 -0.913856103574851 0.362330722081463 AQP12B other 1 1 1 0.698956734049905 -0.913856103574851 0.0580555718164051 107.672169173078 83.3018549518555 1.29255428027752 0.198166089590526 -146.018595121197 143.912068837448 -1.01463759294662 0.31192337703943 SIGIRR other 1 1 1 1.29255428027752 -1.01463759294662 0.00857804199579086 -4956.30079831445 1635.99877059599 -3.02952599194734 0.00288822954575466 -6536.35877759308 2826.34723834258 -2.31265241896679 0.0221106487510599 IFITM2 other 1 1 1 -3.02952599194734 -2.31265241896679 0.554692639144376 412.816565530741 1334.33558319224 0.309379867201867 0.757473675359284 2470.44680544484 2303.97346741452 1.07225488504307 0.285374744804509 TNFAIP2 other 1 1 1 0.309379867201867 1.07225488504307 3.34320382814697e-14 310.712485474598 39.4129026763527 7.8835220035956 5.4254953623756e-13 -37.6201448070859 87.4804563157168 -0.430040564389775 0.667767295721723 ZNF445 other 4.41269473277118e-10 1 7.3971203770629e-09 7.8835220035956 -0.430040564389775 2.54348423686091e-09 31.5911149514331 6.45711228966704 4.8924524670241 3.102537493837e-06 -42.3248018592457 21.002942526329 -2.01518438695853 0.046101465363794 PGBD2 other 2.81004138488394e-05 1 0.0328372568347708 4.8924524670241 -2.01518438695853 5.50344851251598e-21 1112.43904834097 132.503870438279 8.3955211622226 3.01516956007998e-14 -1060.72800882059 441.284204193049 -2.4037298383709 0.0174330793548584 RAB11B other 7.81764861202895e-17 1 4.16877343376658e-10 8.3955211622226 -2.4037298383709 4.33875803579606e-08 32.227643159839 26.1114792775516 1.23423276089706 0.218996302123576 -174.18323735014 41.7303367406896 -4.17401945334173 4.98860370752305e-05 PRMT3 other 0.000443445900611099 0.717909959549641 1 1.23423276089706 -4.17401945334173 0.00702309225888161 5.03106843919251 1.73199380083094 2.90478432242587 0.00423127609729843 -6.5618250451338 8.64267106441284 -0.759235772856478 0.448903003501701 GP1BA other 1 1 1 2.90478432242587 -0.759235772856478 5.91089325914341e-06 140.310330871193 46.7982202885062 2.99819800851815 0.00321833088463806 -183.310937974299 70.8367988562194 -2.58779251651918 0.010685020098262 PRPF39 other 0.049870206427393 1 1 2.99819800851815 -2.58779251651918 0.0173305097451587 56.7092665310198 20.8129623876882 2.72470902866599 0.00723939635001285 37.6525313652029 43.5500860120084 0.864579954097466 0.388717371812627 PPIL6 other 1 1 1 2.72470902866599 0.864579954097466 4.49362540906828e-13 212.847730650904 27.1249823507234 7.84692605137224 9.94096329149252e-13 72.6948736561927 41.7995917024709 1.7391287975642 0.0842101697811173 ZNF74 other 5.76666948745732e-09 1 1.35018163425051e-08 7.84692605137224 1.7391287975642 0.000378243170720741 6.98586956521738 3.89259944110184 1.79465410477477 0.0746575889791296 -8.64668409466153 5.6801365386872 -1.52226694477664 0.129979729779707 KIAA0825 other 1 1 1 1.79465410477477 -1.52226694477664 1.13127959460434e-05 691.839123630673 139.806888307032 4.94853388133004 1.90884296865973e-06 13.4866979655744 615.584438869902 0.0219087701279998 0.982548548693065 UBALD2 other 0.0930024954724231 1 0.0205067000123115 4.94853388133004 0.0219087701279998 0.0441039461369262 1.79328003518617 1.16206662581533 1.54318177232564 0.124812802686048 -8.14092998718817 5.74731488300369 -1.41647537204948 0.158630113841818 CDNF other 1 1 1 1.54318177232564 -1.41647537204948 0.219018754488208 117.673194822888 78.0046266991663 1.50854122123689 0.133718770626603 346.017540871936 352.516065993464 0.981565307943587 0.328044275724463 NOTUM other 1 1 1 1.50854122123689 0.981565307943587 0.000850636130462231 27.5100999754159 10.2365529336799 2.68743786640357 0.00814199031243109 -29.2480742440383 21.3491149567756 -1.36999001144803 0.173051486047746 RBM11 other 1 1 1 2.68743786640357 -1.36999001144803 0.275662566651851 29.0948227053077 25.736727891551 1.13047870062997 0.260078910636688 -33.6345806944315 65.8704471825663 -0.510617160396832 0.610369802283594 NUPR2 other 1 1 1 1.13047870062997 -0.510617160396832 0.000209142343899909 110.293687107745 27.0796465034587 4.0729367384341 7.70908504316128e-05 -111.139704077697 114.616005032628 -0.969670021617477 0.333871404797773 CCDC137 other 1 1 0.713707093295871 4.0729367384341 -0.969670021617477 0.000588082259101884 -4.53012763872062 14.229693178514 -0.318357365959292 0.750648018872464 -67.8176229051729 21.0602321747777 -3.22017451385902 0.00156482055715033 ARL15 other 1 1 1 -0.318357365959292 -3.22017451385902 7.13944082919849e-11 47.598839929861 7.25269365839569 6.56291885081355 7.9570402359423e-10 -26.5385507350711 22.4807716253332 -1.18049999249871 0.239657638529296 C12orf56 other 8.50450191574124e-07 1 1.00744086427266e-05 6.56291885081355 -1.18049999249871 4.74595895019685e-07 194.441856759094 66.5378241134747 2.92227555303716 0.00407056922133173 -245.65992806083 117.638598972259 -2.08825955262151 0.0386391475303255 CDK10 other 0.0044531332829697 1 1 2.92227555303716 -2.08825955262151 0.462908300096575 24.4485158107989 22.2570852307982 1.09845990871115 0.273696175026762 3.87159047535145 49.508403175021 0.0782006735637319 0.93776864140267 SOCS1 other 1 1 1 1.09845990871115 0.0782006735637319 0.00460078963030782 189.885770390352 67.1178415814338 2.82914000087391 0.00529345562566319 -73.6036862195423 121.627527386932 -0.605156478971968 0.545971557560251 TCN2 other 1 1 1 2.82914000087391 -0.605156478971968 2.59098872212095e-06 100.921304897079 58.5858908886194 1.72262132343341 0.0871038741167427 -363.037802949077 93.9961217061817 -3.8622636376837 0.000169230176309015 GAS2L1 other 0.0227022431832238 1 1 1.72262132343341 -3.8622636376837 5.36175226079673e-16 150.076176034506 21.1244530191102 7.10438163292275 4.36695126589792e-11 -113.462339937997 50.0489919512015 -2.26702547872741 0.0247988874913134 ATP6V0A2 other 7.30753215623986e-12 1 5.74483458434944e-07 7.10438163292275 -2.26702547872741 5.87845842869965e-07 20.516648949219 6.77883651198717 3.02657379521382 0.00290582368197892 -29.5813721481725 14.3561411282821 -2.06053784814751 0.0410517348668574 PRKN other 0.0054704934137479 1 1 3.02657379521382 -2.06053784814751 0.175508159449191 2.24107543913568 3.12740586682928 0.716592452199943 0.474732471543432 -7.3538184511848 5.81677024702259 -1.26424426939485 0.20809036252052 HS6ST3 other 1 1 1 0.716592452199943 -1.26424426939485 4.55336988519478e-09 910.927947827915 137.084843123013 6.64499391089131 6.12579094788514e-10 227.697906805512 580.218691823674 0.392434628553313 0.695329694171637 HGS essential 4.95452177208044e-05 1 7.78588029476201e-06 6.64499391089131 0.392434628553313 0.118737398780932 32.0785020454501 51.6617327330234 0.620933529489319 0.535561295162204 -105.604230439495 87.5301766136597 -1.20648940199916 0.229478964932344 TNFAIP8L1 other 1 1 1 0.620933529489319 -1.20648940199916 0.000186448725911772 35.7056728794898 9.25003116628665 3.86005973792017 0.000167197423978678 -43.1635900131927 35.7028237731971 -1.20896851989608 0.228552165286312 RAD51D essential 1 1 1 3.86005973792017 -1.20896851989608 0.00595655400876247 6.18448471121188 9.23450006587865 0.669715162390162 0.504104457556425 -30.982468856172 14.706786718179 -2.10667832816768 0.0368675762229474 MAPK11 other 1 1 1 0.669715162390162 -2.10667832816768 0.0929739131193464 -16.0316567819455 27.0273572300526 -0.593164053943069 0.553919481217074 -134.422411358443 62.5111387150999 -2.15037534304223 0.0330463857434297 SP140L other 1 1 1 -0.593164053943069 -2.15037534304223 2.70909455340873e-22 213.50484485373 19.7412253294904 10.8151769350804 1.51579612089144e-20 -218.888244757573 91.5565402048834 -2.39074395196399 0.018046306530835 MRPL30 other 3.86696156553562e-18 1 2.1739547965825e-16 10.8151769350804 -2.39074395196399 5.1273656611582e-06 44.0362446829636 10.3479257632871 4.25556248569133 3.64557788508424e-05 -29.6731603315112 19.1415850337731 -1.55019348079881 0.123188454733969 TARSL2 other 0.0435723533885224 1 0.349610919179579 4.25556248569133 -1.55019348079881 0.000233317340197095 55.2299480718773 15.3266202764591 3.60353078993598 0.000424006678457068 -25.7049431051373 48.8187113448253 -0.526538747071249 0.599276433510424 SMYD3 other 1 1 1 3.60353078993598 -0.526538747071249 0.00570731455604366 39.8354940497652 77.7826103235425 0.512138817199198 0.609297182618042 -548.688369996395 195.325156012174 -2.80910242796476 0.00562121048580076 METTL7A other 1 1 1 0.512138817199198 -2.80910242796476 2.36873135761659e-10 139.548679867987 22.4098302271664 6.22711901221004 4.26366679717734e-09 48.5243399339933 49.6976435576494 0.976391161840599 0.330392063239867 IFNLR1 other 2.75767704653723e-06 1 5.26562849451401e-05 6.22711901221004 0.976391161840599 0.0396685403333309 13.0683192190758 8.00791148835546 1.63192603190967 0.104778830255355 -16.8925472060759 15.0883614807862 -1.1195746620723 0.264672749000185 SH3BGR other 1 1 1 1.63192603190967 -1.1195746620723 1.19115376476084e-06 233.066139504842 55.0492722337992 4.23377330975402 3.97600771178187e-05 -232.164604287058 108.72766342064 -2.13528551044891 0.034350946226047 FAM174B other 0.010798539309929 1 0.379509936089579 4.23377330975402 -2.13528551044891 0.362373573172094 -22.7737089201878 19.3801684631833 -1.17510376462677 0.241755202549185 -4.6841940532081 28.9615472126487 -0.161738391212826 0.871722508490999 GPRIN3 other 1 1 1 -1.17510376462677 -0.161738391212826 0.452608375232667 -9.89137879474832 8.97443141138101 -1.10217331230639 0.272083848402296 -26.3484657013591 27.8548595095489 -0.945919892086571 0.345652293759568 KRT6B other 1 1 1 -1.10217331230639 -0.945919892086571 2.40311216391066e-06 50.4191755107934 19.8519153905454 2.53976377185276 0.0120707292776258 -103.094909458457 40.6707697748227 -2.53486496639359 0.0122339013169441 PARPBP other 0.0211401777059221 1 1 2.53976377185276 -2.53486496639359 0.227555873678208 5.10161428321082 3.21646385230505 1.58609408265378 0.115092708302473 11.9408371044611 10.7490970245698 1.1108688550459 0.268629035881603 STAC3 other 1 1 1 1.58609408265378 1.1108688550459 0.00659116780179191 155.531783776542 50.3118680898981 3.09135378353742 0.00236303579754494 -8.86308527027925 168.665547929637 -0.0525482849288031 0.958159485609286 ROR1 other 1 1 1 3.09135378353742 -0.0525482849288031 5.8758118706425e-05 69.5958340143044 15.4016374748334 4.51872952652115 1.26966792146595e-05 24.1356221739706 57.5504793151382 0.419381775116195 0.675549369819113 SDHAP1 other 0.443565038114802 1 0.127677806182616 4.51872952652115 0.419381775116195 1.68325010125383e-07 312.677524683199 53.7225260993852 5.82023123977369 3.74812798586193e-08 -160.205680375237 228.161200637471 -0.7021600514357 0.483728706735236 FAAP100 other 0.00164436702391487 1 0.000445015235761387 5.82023123977369 -0.7021600514357 0.28088440721836 147.35488750145 134.353373975568 1.09677102361602 0.274510913171947 -90.510486333939 232.108540863707 -0.389948969551647 0.697131136952709 IRF7 other 1 1 1 1.09677102361602 -0.389948969551647 5.12735271721656e-05 87.6462013892688 21.9525118308679 3.99253634684426 0.000100918328605025 -77.4443472077888 96.5677230748809 -0.801969278572889 0.423806505927486 L3MBTL1 other 0.389935174144319 1 0.923099951750163 3.99253634684426 -0.801969278572889 2.41160236139688e-06 35.7071979294415 7.50074532519549 4.7604866425072 4.46192863526476e-06 13.4860012042925 16.8183519489696 0.801862230330999 0.423884480019924 FAM131C other 0.0212124543708469 1 0.0467074689539516 4.7604866425072 0.801862230330999 0.438616102991569 31.6631905516682 27.8136555417769 1.13840449717619 0.25677871286857 5.17626705841421 48.0507992680673 0.10772488985119 0.914358845828067 LMNTD2 other 1 1 1 1.13840449717619 0.10772488985119 0.68478939447405 7.4513866975211 19.9570546566099 0.373371062300176 0.709433050368137 68.1046947862974 84.4692664901028 0.806265966501286 0.421447279663729 PDE6G other 1 1 1 0.373371062300176 0.806265966501286 0.42531641960378 -10.9086873077901 8.5263088722259 -1.27941498147278 0.202662841036638 -4.43350983883274 17.9081485019066 -0.247569414468543 0.804795221086841 PRKG1 other 1 1 1 -1.27941498147278 -0.247569414468543 0.486963173745623 812.177651515152 1061.90828214345 0.764828436854998 0.445551780840499 1985.20681818182 1702.84155769649 1.16582004309743 0.245501380182005 DLK1 other 1 1 1 0.764828436854998 1.16582004309743 0.000262284278102958 29.4913294797687 14.7698547983228 1.99672440132029 0.047701464890709 -213.036448298009 67.7212711221119 -3.14578336714726 0.00200522320194467 TLCD2 other 1 1 1 1.99672440132029 -3.14578336714726 0.76546164391781 -113.542881475329 230.694924900668 -0.49217763036711 0.623328005918561 -350.01591298588 507.561104909391 -0.689603497195404 0.491530733449324 AHNAK2 other 1 1 1 -0.49217763036711 -0.689603497195404 0.028466123358293 293.588442318323 130.126455586187 2.25617796931285 0.0254401466696274 -16.0453363692599 188.010176728064 -0.0853429141363331 0.932097509981116 OLFML2A other 1 1 1 2.25617796931285 -0.0853429141363331 1.18949345464315e-05 482.122658360519 123.581486970926 3.90125309362837 0.000147619305534466 -532.63522829601 325.707420719163 -1.63531806281831 0.104212874797147 SP1 other 0.0975027784770992 1 1 3.90125309362837 -1.63531806281831 3.56337990331846e-11 107.705071631506 49.8454780007579 2.16077919104053 0.0323897645332189 -387.218482315249 79.464232913245 -4.87286503775849 2.90215212625205e-06 MRPL40 essential 4.29387278349875e-07 0.0422698457188611 1 2.16077919104053 -4.87286503775849 0.420043352342339 -6.35755186764424 5.229254768336 -1.21576632795561 0.226164734957741 -0.409312146589389 11.1720415764868 -0.0366371843308251 0.970827624698301 FAM212A other 1 1 1 -1.21576632795561 -0.0366371843308251 0.000201332326863275 115.966794572647 32.8448599883939 3.53074406813197 0.000572565712552104 2.00886286570837 71.7314153464998 0.028005342652233 0.977700508785178 PDIA2 other 1 1 1 3.53074406813197 0.028005342652233 1.39823998416936e-09 420.28280664167 85.1693528086556 4.93467183654538 2.42971338191e-06 -171.83197643278 154.814981122495 -1.10991827268203 0.269098957827553 PCGF3 other 1.56602878226968e-05 1 0.0259055414952311 4.93467183654538 -1.10991827268203 2.07914130924098e-06 87.0581774451217 16.5609300193415 5.25684109186179 5.4452354074426e-07 6.53435865931203 63.8431462717535 0.102350197960138 0.918627285587709 LMLN other 0.0184107962933289 1 0.00605237915537245 5.25684109186179 0.102350197960138 0.000568421326081983 3273.48164460971 835.083136503267 3.91994701068533 0.000138487684067119 -1507.05296781845 3791.04462348743 -0.397529735862642 0.691586668458016 P4HB other 1 1 1 3.91994701068533 -0.397529735862642 0.00104375785640448 129.400143039394 88.0606179870447 1.46944395800664 0.143820686255683 -327.318281980902 152.133295530384 -2.15152298410265 0.0330465178428282 PSMD13 essential 1 1 1 1.46944395800664 -2.15152298410265 0.637035120915423 -208.254735174351 238.645399924892 -0.872653465098824 0.384448698182963 -380.792028704978 572.986096523618 -0.664574639795439 0.507490753186891 NDUFA4L2 other 1 1 1 -0.872653465098824 -0.664574639795439 0.074988785320609 1937.18325434439 1274.25418385245 1.52024869048317 0.130567702607822 -1244.53924933268 1827.34138118028 -0.681065542623915 0.496887108603941 ZFP36L1 other 1 1 1 1.52024869048317 -0.681065542623915 2.04089450743275e-13 550.205221015685 113.888114683248 4.83110307467944 3.32150803405842e-06 -790.062008701692 210.764921816292 -3.74854601939088 0.000253307964563147 UBE2L3 essential 2.64152976097021e-09 1 0.0350751248396569 4.83110307467944 -3.74854601939088 0.00178977214890331 46.95300246948 14.7353039440532 3.18642918040582 0.00174215945443707 -40.7840405025663 66.5252104690339 -0.613061427615481 0.54073423048473 NTF3 other 1 1 1 3.18642918040582 -0.613061427615481 1.40289443142705e-07 262.965882414315 53.5784430013281 4.90805383067583 2.35989225275006e-06 -88.5337437181563 101.977188553414 -0.868172039002467 0.386677852852338 BRWD1 other 0.00137988696275164 1 0.0251776904445904 4.90805383067583 -0.868172039002467 0.0026661860271299 17.5360754740275 7.07629540337041 2.47814350227312 0.0144311806588962 -29.0990082202492 19.4312944201611 -1.49753318492551 0.136571930224712 PMEL other 1 1 1 2.47814350227312 -1.49753318492551 0.568167728993539 -0.518612054080082 2.76234413439109 -0.187743463105621 0.851328150512662 -12.1032325890078 11.4981593283128 -1.05262348897923 0.294184071678974 POU3F1 other 1 1 1 -0.187743463105621 -1.05262348897923 0.365430570613825 3.80359414758269 2.9912835316299 1.27155921776167 0.205593990096553 6.72109573791348 5.23047117255035 1.28498858251738 0.200873708449466 SNAI3 other 1 1 1 1.27155921776167 1.28498858251738 0.0158914156442745 5.90154961352121 2.40159049399202 2.45735050512771 0.0151284687211832 -11.1786955878546 11.1381797709576 -1.00363756176773 0.317158944152441 LYG2 other 1 1 1 2.45735050512771 -1.00363756176773 0.0796228359332243 -11.3970804110259 25.7247874731019 -0.443038855926129 0.658351386940462 -82.5690751916488 38.238661143276 -2.15930873945277 0.0323542500605267 MORN5 other 1 1 1 -0.443038855926129 -2.15930873945277 0.000838391635632888 52.3322249649283 17.5814052188017 2.97656668017433 0.00340279688184262 -14.715524312556 34.0327982186859 -0.432392429737863 0.666081366230137 EP400NL other 1 1 1 2.97656668017433 -0.432392429737863 0.183676452968383 318.602506838776 231.492953002276 1.37629462455232 0.17074140092699 808.444324528411 462.196297777755 1.74913630510547 0.0822727359067672 PRAME other 1 1 1 1.37629462455232 1.74913630510547 0.00236362725040727 22.5412325017721 10.2726180081228 2.19430260951475 0.0297416643386056 -38.8328267154435 25.9971678241409 -1.49373297038085 0.137332091826399 C6orf201 other 1 1 1 2.19430260951475 -1.49373297038085 0.0161663853412637 11.9694272256334 10.5048817929308 1.13941569848869 0.256395758744994 -78.3630541437763 38.1013436640708 -2.05670054144762 0.0414952056647551 MYBL1 other 1 1 1 1.13941569848869 -2.05670054144762 1.22011948402113e-07 355.54701352606 78.7535761316623 4.51467769452967 1.25840047843758e-05 -198.975287178459 131.053492243264 -1.51827535285453 0.131008632141829 DRG1 other 0.00120511201436767 1 0.126582504126037 4.51467769452967 -1.51827535285453 3.08127402026667e-14 562.408472210624 65.3711721174559 8.60331020530142 7.53219976513843e-15 -50.2615803977217 371.187059439655 -0.135407684938146 0.892463000672973 ANKFY1 other 4.07005485337025e-10 1 1.04931074928144e-10 8.60331020530142 -0.135407684938146 3.81181455434472e-07 310.075158389536 59.7651124100177 5.18823015444646 7.08147266338151e-07 -81.9375711658053 218.68502346722 -0.374683048096741 0.708447419730906 YTHDF3 other 0.00360521420549923 1 0.00780873990591079 5.18823015444646 -0.374683048096741 2.56946330985158e-07 57.8657927932869 10.4516166343949 5.53653992654671 1.97383131562027e-07 -13.8771641163458 43.6445958901857 -0.317958359638893 0.751093169425835 ZNF696 other 0.00246771256278146 1 0.00225431274556992 5.53653992654671 -0.317958359638893 0.00290090151682729 37.0566775324134 10.7719284061649 3.4401154682021 0.000752003191029914 34.6755716771648 39.5463014743637 0.876834757850708 0.381969247735383 ADARB2 other 1 1 1 3.4401154682021 0.876834757850708 0.0218958581264154 -0.796812326237805 19.2744574666208 -0.0413403245003245 0.967077448829959 -93.3403616375557 38.689565982925 -2.41254610296611 0.0170017182941374 NRG3 other 1 1 1 -0.0413403245003245 -2.41254610296611 2.08253164685401e-10 42.1611806875375 6.1841787223563 6.81758768308579 2.04394928932638e-10 75.799209243106 18.7525402386951 4.04207687482774 8.39136466691353e-05 SRL other 2.43135569770206e-06 1 2.63873853252035e-06 6.81758768308579 4.04207687482774 0.466638650171155 592.550407743787 523.09025311031 1.13278808813673 0.259030250340294 979.15816492116 935.836896992521 1.04629147244339 0.297034648293168 IFIT1 other 1 1 1 1.13278808813673 1.04629147244339 0.105631852605249 24.0124697052615 11.4465455804232 2.09779182169418 0.0376116132093168 33.2099235070711 21.9581714582663 1.51241753304413 0.132545798334328 KCNQ5 other 1 1 1 2.09779182169418 1.51241753304413 0.191473293350601 4.00671799375852 6.68583029506003 0.599285027727816 0.549951402802058 -12.8092986750883 10.0492795621994 -1.27464845572322 0.20454522137331 ADAMTSL5 other 1 1 1 0.599285027727816 -1.27464845572322 0.0134549293567073 13.1462795370645 11.8049681068487 1.11362262210922 0.267258718399631 -32.8694527952149 21.9090935765523 -1.50026529762019 0.135690437128884 KCNIP4 other 1 1 1 1.11362262210922 -1.50026529762019 1.68781039025559e-05 556.516488703845 163.067413290024 3.41280012649769 0.000824214239808072 -547.570925501082 291.123185981329 -1.88089081141136 0.0618994866475078 MORF4L1 other 0.1360375174546 1 1 3.41280012649769 -1.88089081141136 2.55917229545343e-10 47.2519170459223 6.64346939975851 7.11253626721603 4.81838030217734e-11 13.1407294383493 24.6548576733532 0.532987438518119 0.594858205559774 WDR53 other 2.97503779346462e-06 1 6.33183355509124e-07 7.11253626721603 0.532987438518119 1.23427416185249e-33 451.174442745284 32.4818397443667 13.8900519889281 4.03317719119003e-29 -186.347827601893 104.033900252192 -1.79122216075877 0.0751840559021975 DMWD other 1.79364721200403e-29 1 5.84851024494467e-25 13.8900519889281 -1.79122216075877 8.00025278174332e-06 605.692794477205 122.170053674174 4.95778446731784 2.72159075923493e-06 122.972877415025 469.708299281495 0.261806907825846 0.793978376815146 SLC52A2 other 0.0667221081997393 1 0.0289196234076304 4.95778446731784 0.261806907825846 0.00576522541489265 47.5128006943608 33.2279034811413 1.42990666628507 0.15480963441378 -126.428096272879 63.4135787681561 -1.99370700611469 0.0479850430898073 PIGP other 1 1 1 1.42990666628507 -1.99370700611469 0.784406561285612 -15.1969788041759 21.9218814641208 -0.693233326211008 0.489214146170653 -13.7580765580513 53.2556428477014 -0.258340258841606 0.796491511415155 IKZF1 other 1 1 1 -0.693233326211008 -0.258340258841606 0.000192315581218476 268.870023860354 63.2889649351866 4.24829232293022 3.93839290305051e-05 194.296747456985 287.354307674596 0.676157420535382 0.500072329728432 PCYT2 other 1 1 0.376234674028416 4.24829232293022 0.676157420535382 2.38777478929404e-11 742.606161427483 104.232691734262 7.12450334987736 3.99271418378794e-11 370.552598888377 194.905211509421 1.90119389840156 0.0591816586437317 NAT8L other 2.89613204193474e-07 1 5.26040093714062e-07 7.12450334987736 1.90119389840156 9.37040659463629e-06 40.6319719117225 17.8427852980081 2.27722136612037 0.0242777691402096 -70.7686729721984 28.1836001818764 -2.51098768487734 0.0131679839976167 GNB1L other 0.0776525594497509 1 1 2.27722136612037 -2.51098768487734 2.53580075163032e-06 33.2146894505663 8.8169437547533 3.76714317051869 0.000233121911828705 -66.1154754565769 29.1558469119179 -2.26765751844962 0.0247141188309178 DNAH14 other 0.0222465799940528 1 1 3.76714317051869 -2.26765751844962 0.758383678747157 0.615029092559749 41.8225507260305 0.014705681071168 0.988286792260494 118.495522634424 160.536104663037 0.738123818832804 0.461608006086629 EVI2B other 1 1 1 0.014705681071168 0.738123818832804 3.49099289587569e-23 53.5427004356208 5.21123222062415 10.2744798483012 4.15875954065987e-19 -43.5844968988223 21.8168766475834 -1.99774228011002 0.0475406453780043 ZNF829 other 5.00189462121069e-19 1 5.93787687215416e-15 10.2744798483012 -1.99774228011002 8.40508389501738e-15 187.523358089264 21.1208777771968 8.87857787291984 1.51878458127251e-15 175.830624482833 87.8423805647863 2.00166051229854 0.0470549073646117 THNSL1 other 1.12300325921327e-10 1 2.12705780607214e-11 8.87857787291984 2.00166051229854 0.0118374203072385 89.6403259630587 72.7744541830314 1.23175538682308 0.220120219078248 -210.71279543551 113.97014416126 -1.84884205408537 0.0666051458209239 TRIM69 other 1 1 1 1.23175538682308 -1.84884205408537 1.97910178710245e-06 1659.97649379148 422.262637322855 3.9311469854774 0.000129785142749635 -962.652799682534 905.200452750755 -1.06346919818388 0.289313080710519 ATP6V0C other 0.0175645283605342 1 1 3.9311469854774 -1.06346919818388 0.0571788425629392 -4484.7406202884 2054.27354836897 -2.18312727818023 0.0305916709457127 -7267.83058530174 3548.9576609631 -2.04787751210575 0.0423279187048168 IFITM1 other 1 1 1 -2.18312727818023 -2.04787751210575 5.43516578236119e-07 1694.63845907587 310.856947159647 5.4515058278738 2.00846591489962e-07 422.560477085608 569.767598410562 0.741636551928179 0.459467166896624 LAMP1 other 0.00507155319152123 1 0.00229266384185792 5.4515058278738 0.741636551928179 0.00101557163149965 38.6584058809606 10.0810574604358 3.83475702154063 0.000216738922228612 41.3197443518056 22.354090342819 1.84841985149618 0.0674103517755103 POMK other 1 1 1 3.83475702154063 1.84841985149618 0.60479141560035 11.5884531694438 27.5265404747432 0.420991994256477 0.674501643527547 -43.3716499662356 63.1621288503276 -0.686671756568108 0.493592698225788 LINC00839 other 1 1 1 0.420991994256477 -0.686671756568108 3.65440910714957e-05 142.055976897498 37.8110275389873 3.75699858331071 0.000260095556507406 -80.0765474593079 81.7732247204695 -0.979251432642391 0.329302970484545 KLHDC8B other 0.283033985348734 1 1 3.75699858331071 -0.979251432642391 4.51083369690231e-08 66.5290641415538 17.0119232236956 3.91073150676384 0.000138667262823943 -85.0605788322819 33.1782941504132 -2.56374177788229 0.0113316655549769 SETD4 other 0.000460330578768881 1 1 3.91073150676384 -2.56374177788229 0.000558983435247334 166.375032034351 50.0395798617563 3.32486868382975 0.00110420422922412 -5.17088038242473 76.6771743858055 -0.0674370231277323 0.946320707227258 PTCH1 ts 1 1 1 3.32486868382975 -0.0674370231277323 0.158554007539694 -16.1162242123781 12.9885374480567 -1.24080361448157 0.216628418593853 -101.822765072765 59.2875396094979 -1.71743954536533 0.0879765231507869 RTN4RL1 other 1 1 1 -1.24080361448157 -1.71743954536533 0.000743249743490496 96.634928084366 56.0612039183949 1.72373979383375 0.0868290241829041 -457.274144420211 165.160138640307 -2.76867135245074 0.0063438774888845 RNPC3 essential 1 1 1 1.72373979383375 -2.76867135245074 0.0199012332077627 9.0701578048045 13.1992252379486 0.687173500057201 0.493071007662836 -59.8368881294601 27.6184084455232 -2.16655815803026 0.0319023233644392 ZNF267 other 1 1 1 0.687173500057201 -2.16655815803026 5.14536498629395e-06 755.932072543092 150.476969002544 5.02357322554997 1.40632029814954e-06 312.940810516988 307.548742302836 1.01753240209593 0.31051710175929 IRS2 other 0.0437098755585671 1 0.015224823547767 5.02357322554997 1.01753240209593 0.000392989120797409 11.4401260856443 2.97173158429414 3.8496498627623 0.000174218672877196 0.364005231212901 9.84108633572065 0.0369883180367653 0.97054317436963 C7orf61 other 1 1 1 3.8496498627623 0.0369883180367653 5.68849208004626e-07 168.28707208165 49.5278667453061 3.39782597435613 0.00086335895946847 -143.726865830321 74.8498023004735 -1.92020368007588 0.0566685594370903 BICD2 other 0.00529939922177109 1 1 3.39782597435613 -1.92020368007588 1.59868860251945e-07 17.8163103732634 3.21118205935084 5.54820936464285 1.28394991681602e-07 6.20673225595856 7.9600115132726 0.779739105352976 0.436781259026479 CCIN other 0.00156463653528578 1 0.00148360412888091 5.54820936464285 0.779739105352976 0.650221608013967 -29.3647502072942 34.1644891050515 -0.859510883274188 0.391507420276047 -40.889256020301 61.9632693463985 -0.659895070928462 0.51039007678904 RASA3 other 1 1 1 -0.859510883274188 -0.659895070928462 1.37800750161594e-09 157.829294711689 24.3837638663556 6.47272076520802 1.53387658036195e-09 -80.4729146450061 93.9956273300351 -0.856134662120522 0.393396761175787 LRCH3 other 1.54447080781114e-05 1 1.92424817006407e-05 6.47272076520802 -0.856134662120522 0.211059433981057 77.5603622158084 62.1285802025949 1.24838459148579 0.213772634661185 -216.987198684913 229.551512930367 -0.945265818181448 0.345994387016248 LEMD1 other 1 1 1 1.24838459148579 -0.945265818181448 0.000614726554021783 947.470933722822 299.068672041807 3.16807149091956 0.00185753257276719 -660.82360950371 973.061953962012 -0.679117713741696 0.498102898599826 NDUFA13 other 1 1 1 3.16807149091956 -0.679117713741696 2.12886296296596e-20 49.2282753245487 5.81680565308907 8.4631115874407 2.17873027777786e-14 -76.8324962856517 23.4343367556107 -3.27862900865997 0.00129659999149848 ZNF566 other 3.01319263778202e-16 1 3.01906654591678e-10 8.4631115874407 -3.27862900865997 5.81993583176236e-27 137.357108278199 12.0208005788989 11.4266189990135 4.12881821719546e-22 -102.370357473481 48.1466359610773 -2.12622035641782 0.0351329108172964 ZNF529 other 8.4127172448125e-23 1 5.94054365090083e-18 11.4266189990135 -2.12622035641782 2.98977017824527e-16 11.7671967341979 1.51540975586328 7.76502638225033 1.01207201197237e-12 -17.2499645074017 6.63338973966164 -2.60047504886718 0.0102042321887461 ZNF284 other 4.08791276471476e-12 1 1.37439379225848e-08 7.76502638225033 -2.60047504886718 0.133839334963695 2.92262803583139 1.89449242653801 1.54269713348614 0.125025453024298 6.26382630562558 3.22264252224323 1.94369256360008 0.0538169650294786 DLEU7 other 1 1 1 1.54269713348614 1.94369256360008 0.000218458796072578 5.89995906743424 4.60574173047027 1.28100084909273 0.202119081690061 -29.8546475880268 11.1190323903355 -2.68500410287284 0.00804764892145777 MATN1-AS1 other 1 1 1 1.28100084909273 -2.68500410287284 0.000374775770837682 122.218637458973 32.2730899533599 3.78701381353937 0.000217157807975632 -8.67931825073047 100.667365420802 -0.0862177947585081 0.931403846206102 AIDA other 1 1 1 3.78701381353937 -0.0862177947585081 5.46688311268486e-06 76.4991856677527 20.1888762778043 3.78917501970409 0.000216853446880044 -24.3726927252986 28.7752348769577 -0.847002390406741 0.398316718140843 C15orf41 other 0.0463044999644408 1 1 3.78917501970409 -0.847002390406741 0.304268373529606 -5.30683060718988 3.43035423058949 -1.54702116762966 0.123884409287631 0.938120634637274 15.1602474330646 0.0618802983776655 0.950737367839493 CD300LF other 1 1 1 -1.54702116762966 0.0618802983776655 0.874879318990211 10.3671416030807 424.044827337526 0.0244482208830926 0.98052633016472 652.277051599898 1316.15124678078 0.495594296776549 0.62087810548122 KRT5 other 1 1 1 0.0244482208830926 0.495594296776549 0.00577413622379681 57.0098032262816 18.6396690957989 3.0585201343049 0.00263216980261328 -22.7821741668349 65.4988161115212 -0.347825739751463 0.728455446485933 GSAP other 1 1 1 3.0585201343049 -0.347825739751463 6.07348066995079e-08 22.383388377486 13.4032425219957 1.66999801285049 0.0969379988222573 -80.6584217553226 21.3127456847349 -3.784515751675 0.000219635620609373 CYP2R1 other 0.000614575508992321 1 1 1.66999801285049 -3.784515751675 0.00149322312184514 3.74332913064621 1.89781865311895 1.97243773765964 0.0503503979553567 -2.15363331626438 2.61933421823243 -0.822206384077895 0.412230649955953 LRRC70 other 1 1 1 1.97243773765964 -0.822206384077895 1.57325746850263e-10 123.855806237558 17.4976720003544 7.07841627360768 5.02809612397384e-11 60.5695610958385 75.7400137756877 0.799703592281114 0.425130537049811 ANKRD46 other 1.84700426802208e-06 1 6.60641549728923e-07 7.07841627360768 0.799703592281114 3.93072353909855e-05 288.640044397439 98.4009357796824 2.93330588891653 0.0038806343286953 -217.501526629121 146.334415392283 -1.48633201592433 0.139290171522458 PIP5K1C other 0.302822941452152 1 1 2.93330588891653 -1.48633201592433 1.39517071078039e-09 153.22029324458 27.0473256634434 5.6648962322981 7.02921020244945e-08 -16.7909536977661 38.7392047265499 -0.433435683987038 0.665304797158729 ZBTB6 other 1.5628702302162e-05 1 0.000823120514706831 5.6648962322981 -0.433435683987038 0.049697382481774 3.53046527610535 13.9733060595559 0.252657836381603 0.800867385131343 -83.7404474780166 38.881932791688 -2.15371102888996 0.0328086269561149 C2orf76 other 1 1 1 0.252657836381603 -2.15371102888996 1.22415507175652e-11 97.5674108310801 14.8011856613849 6.59186453458426 6.53541721902402e-10 28.5118019825006 26.9433793313197 1.05821180156706 0.291615936978365 WWOX other 1.50044687145196e-07 1 8.29475153438529e-06 6.59186453458426 1.05821180156706 0.0771060245415933 11.1175135698734 5.12763750427086 2.1681551319908 0.0316625387671972 -0.965650246523621 16.9383160110058 -0.0570098140745622 0.954610332663952 CYP4Z1 other 1 1 1 2.1681551319908 -0.0570098140745622 1.64628571771398e-07 46.8951883602995 10.0286348368044 4.67612881747348 6.23179657164043e-06 -19.9189929968606 20.6672638817686 -0.963794390530424 0.336621799692476 CIDECP other 0.0016099028033525 1 0.0644118493644755 4.67612881747348 -0.963794390530424 2.96571965358745e-06 52.8573925166338 17.4848813816192 3.02303409231015 0.00295033746497657 -140.844257312569 48.2587221990551 -2.91852438055907 0.00406647690984983 CCDC84 essential 0.0258017609862108 1 1 3.02303409231015 -2.91852438055907 5.4306939723494e-11 1310.55296600491 204.66727776523 6.4033341348695 1.82029589324619e-09 -706.244558746053 579.502917129225 -1.2187075127157 0.224855779576899 BCL9L other 6.49945454610776e-07 1 2.27846436957626e-05 6.4033341348695 -1.2187075127157 4.29985546059156e-11 341.695066016165 108.711924004166 3.14312407903913 0.00200333533404209 -723.322404421464 177.560866928397 -4.07365889192887 7.3648250669179e-05 POLR1D other 5.16412640817046e-07 1 1 3.14312407903913 -4.07365889192887 6.93254394801265e-06 226.289313854235 48.6658770520574 4.64985586537719 7.0022018529899e-06 467.626677974756 191.219385759829 2.44549827475178 0.0155702742203752 KIF18B essential 0.058094718284346 1 0.0720246482598541 4.64985586537719 2.44549827475178 6.52354777712723e-20 457.949647596673 57.5902223749619 7.95186454768358 3.88080756794626e-13 -43.3048447520476 97.0527678403921 -0.44619896697088 0.656088510335432 ZNRF1 other 9.21124946130364e-16 1 5.29963081478741e-09 7.95186454768358 -0.44619896697088 0.606860897789357 -5.0496931521277 6.44461362524293 -0.783552505358667 0.434498393463868 -11.053035059648 11.479053309421 -0.962887335890022 0.337103845942615 FFAR4 other 1 1 1 -0.783552505358667 -0.962887335890022 0.00235500152434293 219.448435673707 78.049004206454 2.81167502269761 0.00575143799324506 -68.9729810541195 122.110184978019 -0.564842163383302 0.573226825891292 SAPCD2 other 1 1 1 2.81167502269761 -0.564842163383302 0.878575599341622 -17.660998811699 39.4685051595982 -0.447470679223434 0.655148117274637 -47.9054789619619 121.845126716711 -0.393166967385917 0.694726152333492 EDARADD other 1 1 1 -0.447470679223434 -0.393166967385917 0.25980696565429 -0.844542036839871 1.42860978872024 -0.591163551802635 0.555277534389021 -14.550117911395 8.85954498592923 -1.64230984034773 0.102566233913446 CYP4F12 other 1 1 1 -0.591163551802635 -1.64230984034773 8.83945530923366e-09 155.061704890264 25.6023804769969 6.05653466596916 1.01125841689115e-08 7.62654734697993 78.6522212363042 0.0969654413709003 0.922879104680408 MARC1 other 9.45468139875633e-05 1 0.000123029698998977 6.05653466596916 0.0969654413709003 0.000241233926992593 26.5855259025044 9.29944951172975 2.85882791975708 0.00486194903407782 -11.3584444886507 15.5003814977001 -0.732784834382045 0.464840897390507 SOWAHB other 1 1 1 2.85882791975708 -0.732784834382045 7.72378164001481e-12 131.262143493761 24.3411111911613 5.39261098077662 2.56460862086528e-07 -67.6912407445496 46.3777142187063 -1.45956397129306 0.146446794254688 BLOC1S4 other 9.53191892194227e-08 1 0.00290826617606122 5.39261098077662 -1.45956397129306 0.0104725823922357 31.6414398541919 13.7743844484307 2.29712187667281 0.0229589523707353 -11.1309264884569 27.8028048455209 -0.400352646083838 0.689451622309968 ZNF749 other 1 1 1 2.29712187667281 -0.400352646083838 7.77952646456492e-09 37.9115719115332 6.78847286060568 5.58469816260717 1.04221316071001e-07 11.1445714728122 13.9154979026988 0.800874790879802 0.424446044777319 KLHL32 other 8.34276418059942e-05 1 0.0012096968156361 5.58469816260717 0.800874790879802 3.16791628929719e-12 356.060313812249 50.4842929626209 7.05289294782994 5.26219246103528e-11 77.632233594307 113.836696113826 0.681961408267526 0.496268186066368 MKL2 other 3.96084573650827e-08 1 6.90925870133933e-07 7.05289294782994 0.681961408267526 1.31584099179134e-12 35.2859886647045 6.27158399014417 5.62632800902557 8.39013015237163e-08 -21.6022002928134 12.6279020262836 -1.71067214869508 0.0891422909261071 ZNF17 other 1.66506519101276e-08 1 0.000978373077068056 5.62632800902557 -1.71067214869508 6.16406944510854e-05 15.0048421807747 4.49581426788031 3.33751380433454 0.00105840321202769 -16.5384086561454 12.3459388342146 -1.33958290886004 0.182341782743195 KDM4D other 0.464031147827771 1 1 3.33751380433454 -1.33958290886004 0.216711970743306 39.7823609518347 29.4457163001073 1.35104069285928 0.178816154419266 -69.4555977637614 99.730371229722 -0.696433763429751 0.487287695873002 GPAT2 other 1 1 1 1.35104069285928 -0.696433763429751 8.9678330097324e-10 537.477334155291 160.126090682057 3.35658812293428 0.000994076088796217 -1084.33307023624 316.064751214744 -3.43073077927474 0.000772870395677653 PPP1CC other 1.01462062672112e-05 1 1 3.35658812293428 -3.43073077927474 0.00162008449899492 22.566378185418 7.65110392624769 2.94942774310022 0.00370159972994969 -5.33194342367749 11.5075039811071 -0.463344912366004 0.643797811871729 ZNF555 other 1 1 1 2.94942774310022 -0.463344912366004 0.0367192276649899 16.5901002532938 8.49035977901234 1.95399260868821 0.0524790970272863 -7.71841808390635 12.6612074427495 -0.609611533402871 0.543000407287283 PRELID2 other 1 1 1 1.95399260868821 -0.609611533402871 8.640770683134e-07 495.710681688082 111.714864836692 4.43728488964046 1.74010315821369e-05 -447.106930160691 309.221930263017 -1.4459095115938 0.150261338477259 BACE1 other 0.00792013040816062 1 0.172566030200052 4.43728488964046 -1.4459095115938 8.29232868580135e-24 9.67921443712853 0.812968611522438 11.9060124830679 2.17495377201195e-23 1.92592977859246 3.9505552556926 0.487508629531828 0.626614439007392 RGS9BP other 1.19036378284678e-19 1 3.13650083461843e-19 11.9060124830679 0.487508629531828 0.494681788650557 -406.952639837958 436.430390420243 -0.932457154154868 0.352740714267965 74.4869176664385 899.42606288391 0.0828160543042354 0.934118682614581 THBS2 other 1 1 1 -0.932457154154868 0.0828160543042354 0.0348101326188629 163.428880636892 105.591944986522 1.54774003507325 0.123778206635373 -137.636844490439 142.091248060025 -0.968651105325613 0.334268245441224 RXRA other 1 1 1 1.54774003507325 -0.968651105325613 0.000391879579357863 14.8029205517451 20.2702022193207 0.730279865567183 0.466307434981535 -87.0765199969178 32.9775435055822 -2.6404792698455 0.00911505306102969 ANKRD37 other 1 1 1 0.730279865567183 -2.6404792698455 0.269700078862639 5.56167970517878 5.2123386819617 1.06702193478448 0.287621055484855 -3.74734380724552 7.76189714801196 -0.482787099054168 0.629928079124367 C9orf47 other 1 1 1 1.06702193478448 -0.482787099054168 0.420805787153014 75.0481645477232 74.618256873898 1.00576142745537 0.316097871098908 -129.384788094063 244.918746184497 -0.528276377817962 0.598063065285268 CYP4X1 other 1 1 1 1.00576142745537 -0.528276377817962 0.00016108353273373 206.27209738478 58.9843084798547 3.49706731672933 0.000614920099778563 -438.080488313134 243.212158302575 -1.80122774852451 0.0736234838151632 KRT10 other 1 1 1 3.49706731672933 -1.80122774852451 0.585790364426981 2.64661354581673 4.6895749137931 0.56436107631684 0.573324180870876 16.6939973439575 19.0645303832152 0.875657412398429 0.382571259347993 CD300E other 1 1 1 0.56436107631684 0.875657412398429 8.84239617897953e-06 60.0897179439285 13.3568467063894 4.49879520704417 1.34981039777925e-05 -45.4482263241013 59.7279775390385 -0.760920228621437 0.447883542074781 CCDC30 other 0.0734537850587829 1 0.135291496169414 4.49879520704417 -0.760920228621437 0.358256758092522 15.8519862107668 39.1599443951525 0.40480103982806 0.686185477609256 -60.9908105182989 58.5818007834692 -1.04112215231713 0.299450586243267 GLDN other 1 1 1 0.40480103982806 -1.04112215231713 2.69596760481674e-14 590.395679392157 69.7048793184206 8.46993331263305 1.9549739894127e-14 613.144752217036 284.543386301137 2.154837475534 0.0327494168460869 KPNA4 other 3.56622594765158e-10 1 2.71135342591647e-10 8.46993331263305 2.154837475534 1.14114631817006e-10 44.5219638242894 6.48912148869719 6.86101560925283 1.62117266185279e-10 26.9857881136952 12.5431709298644 2.15143270107591 0.0330217779701485 TRDN other 1.34826437491793e-06 1 2.09925647983317e-06 6.86101560925283 2.15143270107591 8.09065018289558e-10 49.1706347463211 8.79746686366408 5.58918101179887 1.01137177888219e-07 -28.8202284208215 19.3702005704244 -1.48786422298724 0.138831471233154 ZNF501 other 9.17722450245846e-06 1 0.00117491059552744 5.58918101179887 -1.48786422298724 1.25048255327362e-12 88.2490924368822 14.8031818789091 5.96149484339009 1.64387261319939e-08 -84.4088473444969 32.641716959036 -2.58591934518722 0.0106384964237831 ZNF197 other 1.58336100895505e-08 1 0.000198168843521187 5.96149484339009 -2.58591934518722 2.55021437402894e-06 13.6108181874574 3.32595996896557 4.0922976567546 6.85041798562886e-05 -6.97279170026673 7.55294499989462 -0.923188464945 0.357343868784422 SPATA12 other 0.0223653800602338 1 0.637741756249949 4.0922976567546 -0.923188464945 3.31211534704835e-11 5854.93740918923 1487.36163281272 3.93645854513343 0.000124584931727469 -3855.05981401958 2090.88898854368 -1.84374198493659 0.0671301890488849 RPS23 essential 3.99540474314443e-07 1 1 3.93645854513343 -1.84374198493659 0.549519983287736 -45.7445699730798 43.1535666584148 -1.06004146389971 0.2907537970354 -47.3366978971014 66.6542099575936 -0.71018316663295 0.478644096118254 GNG2 other 1 1 1 -1.06004146389971 -0.71018316663295 0.0479315578114229 84.9481661840835 45.8657500289663 1.85210459068989 0.0660442551245257 -149.021803983504 146.737478397988 -1.01556743110523 0.311527001938552 BTN3A2 other 1 1 1 1.85210459068989 -1.01556743110523 1.6106695372559e-05 51.818568553694 12.8989080256701 4.01728335844941 9.2044444915927e-05 -57.7799420900237 42.8437049320436 -1.34862151118049 0.179451412108267 PCLO other 0.130158205305649 1 0.845704359887537 4.01728335844941 -1.34862151118049 6.62007643318938e-05 38.5833057303742 8.66505608747022 4.45274737299925 1.62005256077896e-05 30.7439549519709 11.9959730108684 2.5628562955349 0.0113399872439742 RGS7BP other 0.496770535546531 1 0.161114227169467 4.45274737299925 2.5628562955349 0.666059307376156 46.1653157357526 58.2849313405615 0.792062625346618 0.429558550367972 -19.3664234081307 167.063936848386 -0.115922225786563 0.90786719047039 INSIG1 other 1 1 1 0.792062625346618 -0.115922225786563 2.28784979352513e-14 40.7851402317361 5.4096785565128 7.53929088497027 4.17376873123978e-12 8.6578736404596 13.8951571216373 0.623085695589414 0.534174418616167 ZNF396 other 3.03277368629692e-10 1 5.60829304416689e-08 7.53929088497027 0.623085695589414 3.67644716069042e-10 119.736580190429 50.9725678738802 2.34903959491877 0.0201086057992625 -490.636174724278 112.302320015762 -4.36888725589477 2.30142240188914e-05 TMEM222 other 4.24372295758495e-06 0.333038835777377 1 2.34903959491877 -4.36888725589477 0.000138606848105193 16.6805619093148 5.61059004970465 2.97304949417805 0.00342971641128038 -11.4617291214651 12.5276805699009 -0.914912306193626 0.361686784743001 CLCNKA other 0.997276272116865 1 1 2.97304949417805 -0.914912306193626 1.25442385607641e-07 165.70122349216 34.0595407632365 4.86504573399934 2.80353856545042e-06 -146.412723762967 95.4581567585986 -1.53378955486461 0.127133273645977 SEPT10 other 0.0012378654611762 1 0.0297595618722562 4.86504573399934 -1.53378955486461 0.109258142525079 -9.3167185520003 6.42788911300368 -1.44942116894215 0.149253349418164 -75.0659412844588 39.8626505368099 -1.88311465177514 0.0615705298892973 CYP4F3 other 1 1 1 -1.44942116894215 -1.88311465177514 1.21483525300985e-13 88.4257767095492 10.6361164109457 8.31372780186471 5.34591069505434e-14 -6.54585393723288 48.8717844569465 -0.133939327363817 0.893631292580796 SMYD4 other 1.58135104884292e-09 1 7.36933789313241e-10 8.31372780186471 -0.133939327363817 0.515599884191913 -6.33869712720595 9.65994332528575 -0.656183676628191 0.512672641460765 -34.5507277952421 31.5793535642815 -1.09409230701674 0.275600971783383 FOXD2 other 1 1 1 -0.656183676628191 -1.09409230701674 1.27343796906011e-07 367.470802260703 62.2857782592443 5.89975452712858 2.16562686563595e-08 295.567008540837 246.034142823961 1.20132517035376 0.231434214578021 GPATCH8 other 0.00125586452508708 1 0.000259766942533033 5.89975452712858 1.20132517035376 1.74219386700483e-26 105.077216055584 8.53074022022697 12.3174792975689 8.76991371085391e-25 -26.0117504716087 36.2479895061799 -0.717605330005241 0.474073869472145 CEACAM19 other 2.51625060211507e-22 1 1.2663755398473e-20 12.3174792975689 -0.717605330005241 0.0785128485606042 295.167790647956 144.629411566773 2.04085591893377 0.0430422907666454 -36.287382905121 266.365740131449 -0.136231419578259 0.891823467573089 NF2 ts 1 1 1 2.04085591893377 -0.136231419578259 4.96696093087038e-07 1175.04734327 208.848802357087 5.62630635181194 8.39100421565942e-08 641.177688019112 744.145892591452 0.86162900904585 0.390222705049136 UBE2H other 0.00465056551957393 1 0.000978373077068056 5.62630635181194 0.86162900904585 0.00081767413313213 57.4786068315906 16.3624311282241 3.51284026078764 0.000581138352517178 -26.4764769486433 52.6251397199851 -0.503114615743024 0.61559787033493 HPDL other 1 1 1 3.51284026078764 -0.503114615743024 2.72939380963059e-08 18.8625809435707 4.28084694222318 4.40627315065248 1.93260707437408e-05 -12.0858310206599 6.65353626824825 -1.81645226438991 0.0711963916672439 KTN1-AS1 other 0.000282983550182499 1 0.19083179482123 4.40627315065248 -1.81645226438991 1.38349384660626e-19 120.005698864433 14.2238046145723 8.43696198846034 2.14509480608843e-14 -21.8662186317118 29.212961906374 -0.748510839188161 0.455286379473351 KATNA1 other 1.95017292617618e-15 1 2.97288689175796e-10 8.43696198846034 -0.748510839188161 1.46792169120524e-08 33.2148706945831 6.79463230507029 4.88839854804175 2.57249591885477e-06 -23.8748123108818 11.8893556152925 -2.00808295112084 0.0464177695279856 FSD2 other 0.000154968492940538 1 0.0273816465602901 4.88839854804175 -2.00808295112084 7.15638587237329e-09 601.361680053198 108.616869354324 5.53654035167841 1.36893614880867e-07 -635.93213429006 391.435169510112 -1.62461675348677 0.106372021468957 ARAP1 other 7.69812428291195e-05 1 0.00157920474126568 5.53654035167841 -1.62461675348677 4.51399244307981e-14 137.106545253806 20.0988692511592 6.82160491421169 2.14568805427551e-10 -80.9118775941712 52.2553523896618 -1.54839406671342 0.123663157858802 KIF24 other 5.94583084602472e-10 1 2.76686474598827e-06 6.82160491421169 -1.54839406671342 0.475238432835979 14.5249435119713 12.1433927389872 1.19611906031319 0.233562861766249 26.4999251468341 43.7625483359052 0.605538894660119 0.545748454432667 PDE2A other 1 1 1 1.19611906031319 0.605538894660119 0.0727732344912504 13.6012655583359 5.89069915784783 2.30893909090838 0.0223798119181363 10.4915575281222 13.4422048419053 0.78049379930704 0.436390328053088 CARMIL3 other 1 1 1 2.30893909090838 0.78049379930704 3.93503056457377e-05 191.699094592884 45.8846324936093 4.17784962360945 4.89865846232127e-05 56.9250664809423 71.652158776744 0.794464081093651 0.428140034247382 PRR5 other 0.303115404389118 1 0.463902956381824 4.17784962360945 0.794464081093651 0.000684005706465024 150.874437494693 44.3005815222049 3.40569880372948 0.000844375554595449 -144.60276229021 166.872508217853 -0.866546346276705 0.387556433819771 ZFP91 other 1 1 1 3.40569880372948 -0.866546346276705 5.32076688523493e-06 121.329171101831 23.6906703455873 5.12139037570251 8.94562247340377e-07 -15.2227135020053 95.3619966178039 -0.159630817746147 0.873381075828436 C17orf58 other 0.0451041408861365 1 0.00980171854410851 5.12139037570251 -0.159630817746147 3.18281022161002e-05 20.4870423693953 9.30682543816956 2.20129221349452 0.0292330634796661 -70.1380090497738 23.6952266532626 -2.96000583054631 0.00357330891647315 BCDIN3D other 0.248768446921039 1 1 2.20129221349452 -2.96000583054631 8.62778630640519e-07 107.26908926836 27.0652567438449 3.9633501460412 0.000113380537632149 -47.7489067055393 41.3647544838872 -1.15433796963884 0.250173293068127 LYRM7 other 0.00790909170708163 1 1 3.9633501460412 -1.15433796963884 0.00203554778225492 56.9242055864316 37.9625462583328 1.49948333810556 0.135782329343053 -157.784358774366 76.2660902007171 -2.06886649570089 0.0402192780978761 CFAP73 other 1 1 1 1.49948333810556 -2.06886649570089 0.0444362892314698 64.5991562376126 91.9870579629655 0.702263532154932 0.483574916130938 -259.021674500255 149.20012048732 -1.73606880245294 0.0845516764178306 CCDC73 other 1 1 1 0.702263532154932 -1.73606880245294 4.22302934818766e-76 1286.05812708503 35.1836090755007 36.5527630870747 3.41469936583221e-77 404.281830989089 193.620395396943 2.08801262986921 0.0384645949340576 BCR other 6.17364660411554e-72 1 4.99297341271985e-73 36.5527630870747 2.08801262986921 0.238451749488581 4.79945062064318 3.35592486942731 1.4301424517475 0.154872791920646 -12.072170825883 14.2527148861387 -0.847008511874718 0.398415638116311 FSCN2 other 1 1 1 1.4301424517475 -0.847008511874718 1.28661827529571e-05 16.1757426911633 4.12254998051095 3.92372263953935 0.000142540198638218 -0.978093168973053 7.53251747187969 -0.129849439131666 0.896892613575155 ZNF732 other 0.105129579274413 1 1 3.92372263953935 -0.129849439131666 0.000903866839496306 36.9338833570415 16.7068313150467 2.21070546895256 0.0287651914356775 -67.9013598862018 35.3956651349054 -1.91835242048442 0.0572093643628667 HYAL3 other 1 1 1 2.21070546895256 -1.91835242048442 0.000125105148015276 48.9895978383397 14.2590610996036 3.43568187948236 0.000756405575557789 -7.83882534314685 27.4659402944203 -0.285401674186968 0.77571259736842 VSIG10L other 0.906762112814721 1 1 3.43568187948236 -0.285401674186968 9.26438819379956e-25 227.374445702396 21.118712926302 10.7664916179251 2.19124933793881e-20 29.5969628607184 53.8591363168773 0.549525389463848 0.583462157346991 ZNF397 other 1.33342339273357e-20 1 3.1404985511339e-16 10.7664916179251 0.549525389463848 3.00999113404855e-18 150.761933280284 19.3223759806403 7.80245314713563 9.56385440707164e-13 -51.7331617004069 49.2779311664941 -1.04982413984908 0.295487444057774 ZSCAN30 other 4.20646260983285e-14 1 1.29944089828882e-08 7.80245314713563 -1.04982413984908 0.0686393448753363 154.853844873556 108.174775435061 1.43151528857592 0.154295861838285 -190.282562226479 217.321228260914 -0.875582030109029 0.382612125045755 TPCN1 other 1 1 1 1.43151528857592 -0.875582030109029 0.0243046697184946 90.356271026857 34.2785459841096 2.63594234915166 0.00923247703075766 167.70971282911 78.5725969089494 2.1344555153682 0.0343579224800707 LILRB4 other 1 1 1 2.63594234915166 2.1344555153682 0.0658326941371473 0.382921947965299 7.25589187850152 0.0527739324644375 0.957997646580954 -31.8792528352235 16.1575135718086 -1.97302961829758 0.0507348239332325 TNFRSF4 other 1 1 1 0.0527739324644375 -1.97302961829758 0.212728149804507 24.7411174585482 51.8063945978852 0.47756879533088 0.633621336254653 -363.575310018113 221.080520235808 -1.64453797028484 0.102065960578012 KRT16 other 1 1 1 0.47756879533088 -1.64453797028484 3.43046106808135e-05 323.778243191139 72.6293006296445 4.45795622956867 1.57341612496973e-05 540.391461320061 291.981117536815 1.85077537163658 0.066092959887225 HEXIM1 other 0.266964555238886 1 0.156602106918237 4.45795622956867 1.85077537163658 0.562614159151453 -71.6409363243693 115.781810280204 -0.618758129200009 0.536972434744274 -463.061585620732 494.091570148292 -0.937197907427873 0.350096211358194 KRT14 other 1 1 1 -0.618758129200009 -0.937197907427873 2.90794738163044e-06 37.9536100709244 13.02546506166 2.91380076575074 0.00410271032872394 -47.6830273171237 23.9446265031843 -1.99138739168817 0.0482068533238133 PDZD7 other 0.0253340375887644 1 1 2.91380076575074 -1.99138739168817 2.81698041126343e-07 203.590971569754 48.2402664612123 4.22035337913093 4.25140111534876e-05 -123.953622507569 86.0065483563264 -1.44121145280738 0.151651746363246 POFUT2 other 0.00269444176337347 1 0.404903442225816 4.22035337913093 -1.44121145280738 0.0642921239902449 22.6405600210726 9.9157227731874 2.28329901298711 0.0237627356259848 32.3566382771535 41.704838782238 0.775848539928516 0.439013035568624 MAPT other 1 1 1 2.28329901298711 0.775848539928516 0.405785379726186 22.5629169446298 28.1527865354292 0.801445246502871 0.42441947433832 -31.0742369913275 62.6909879787747 -0.495673110174119 0.621009528691836 TNFRSF18 other 1 1 1 0.801445246502871 -0.495673110174119 0.110726426483193 39.9079887455741 19.2382020120749 2.07441364429617 0.0396943259441801 7.36469398077899 57.706100457218 0.127624183967153 0.898611817730243 FGF3 other 1 1 1 2.07441364429617 0.127624183967153 0.527256629374233 16.5760429382472 51.1709218538654 0.323934811758625 0.746444712813703 -122.200154581135 138.209823361615 -0.884164031245507 0.378041747130785 C1QL4 other 1 1 1 0.323934811758625 -0.884164031245507 0.870576014287353 7.43905786231772 23.0361255769522 0.3229300794297 0.747203982322949 -25.1278141256821 83.1801859081672 -0.30208893922675 0.763008363322423 RTN4RL2 other 1 1 1 0.3229300794297 -0.30208893922675 4.61648322024444e-12 122.694790674562 21.942488168238 5.59165349589497 1.01697331870496e-07 -91.4410948693525 48.1279833103623 -1.89995691861173 0.0593325183199079 ZDHHC17 other 5.74013523605193e-08 1 0.00118121450967581 5.59165349589497 -1.89995691861173 2.31580775195657e-21 656.17245841035 111.297449847998 5.89566480909043 2.30166626097968e-08 -471.031238447321 206.868878507001 -2.27695553747289 0.0241750170955962 ZNF395 other 3.29655233491018e-17 1 0.000275854701378415 5.89566480909043 -2.27695553747289 7.82225108175958e-13 481.921788322817 59.4305219148475 8.10899471845996 1.4054871649053e-13 281.832785487797 277.17747908332 1.01679539917844 0.310825136047159 ZACN other 9.96163675262082e-09 1 1.92903113383252e-09 8.10899471845996 1.01679539917844 0.000609768999141488 217.644094972791 59.1426547794133 3.67998521176546 0.000322007029197 96.1669959834156 92.1331828747703 1.04378241348861 0.29822177346723 PPARA other 1 1 1 3.67998521176546 1.04378241348861 0.00973327911476121 -0.18814985874543 6.83690987539468 -0.0275197219466885 0.978080159383171 -24.7530976355984 10.3373007408386 -2.39454169479744 0.0178200332592139 TMEM232 other 1 1 1 -0.0275197219466885 -2.39454169479744 0.681433376715938 -5.99407537028943 39.0717752466448 -0.153411902388647 0.878276939191865 -158.181307418287 181.726080905948 -0.87043811559527 0.385433612721669 FAM183A other 1 1 1 -0.153411902388647 -0.87043811559527 0.0596698860153811 14.7999095036745 9.20627571025649 1.60758921082347 0.109960292332689 -6.6527203507513 14.1714026280967 -0.469446851898867 0.639409972217556 EFCAB6 other 1 1 1 1.60758921082347 -0.469446851898867 4.4773074064749e-06 12.1515683635359 2.85558846453944 4.25536400445424 3.61172392632554e-05 -3.80118240081291 9.46414981664397 -0.401640134027467 0.688505705538792 KANK3 other 0.0382720237105474 1 0.346581027970199 4.25536400445424 -0.401640134027467 1.53492552990213e-11 1139.09629402286 148.283992965514 7.68185608737808 2.20810786119686e-12 627.137000215569 235.973198937218 2.65766198466641 0.00875760833980849 EMID1 other 1.87491153477546e-07 1 2.98227047733248e-08 7.68185608737808 2.65766198466641 0.000810617714370407 535.754347555256 230.177116654132 2.3275743277308 0.0213377142788705 -633.788779899749 514.224048610314 -1.2325148573128 0.219779358427016 ESPN other 1 1 1 2.3275743277308 -1.2325148573128 0.000127606404433785 4.82864776392356 60.2586418399582 0.0801320377705829 0.936235610010966 -303.758635006981 84.1835415864591 -3.60829004437895 0.000415368626189471 PTRH1 other 0.922977123269567 1 1 0.0801320377705829 -3.60829004437895 0.578670645238922 0.187239770841812 8.00643065932226 0.0233861727914674 0.981372314162942 -16.1515467283241 18.3562959101406 -0.879891390255999 0.38028030462892 GPR141 other 1 1 1 0.0233861727914674 -0.879891390255999 2.80720388840144e-10 315.144315523312 44.9362034580504 7.01314956029854 6.77374544761512e-11 408.683748847981 89.3664021971836 4.57312523274951 9.77245240825189e-06 TMPRSS6 other 3.25804083287871e-06 0.14193509877745 8.86954228910724e-07 7.01314956029854 4.57312523274951 0.615411652426126 -1.94457844725117 5.82241959052175 -0.333981159725542 0.738845205435162 -18.8338743648383 19.1108686481454 -0.985505929196263 0.325911474892236 CYP4A11 other 1 1 1 -0.333981159725542 -0.985505929196263 0.00879102317458433 54.5807883455365 26.8557742689343 2.03236696134557 0.0438808897003187 -144.411290261391 88.7073888879032 -1.62795108808669 0.105633893102816 TMEM216 other 1 1 1 2.03236696134557 -1.62795108808669 7.73122148644418e-09 183.891436000703 46.4378407193382 3.95994803272849 0.000115467978103745 -226.785289183949 80.7695647482365 -2.80780625586942 0.00565173299287362 RPS19BP1 essential 8.29328128850868e-05 1 1 3.95994803272849 -2.80780625586942 1.40304062192125e-06 243.278003215082 52.1919220115506 4.6612194730296 7.13449949137554e-06 -219.013461208309 158.508585877745 -1.38171355195377 0.169214501106643 TMEM262 other 0.0126315747191571 1 0.0733202967844301 4.6612194730296 -1.38171355195377 0.768992648779261 2.91712208839602 4.06323386019423 0.717931132877639 0.473916411775318 3.04896446826196 17.1289253142466 0.178000920216871 0.858962415168414 C3orf70 other 1 1 1 0.717931132877639 0.178000920216871 2.39565933630319e-05 498.603234407604 192.567379102774 2.58924038292849 0.0105468970666692 -516.835011537657 307.829955671043 -1.67896269357867 0.0952004419756551 TEAD1 other 0.190119524929021 1 1 2.58924038292849 -1.67896269357867 1.52489038112349e-05 105.853210617899 30.7850782173878 3.43845839436951 0.000751517484510098 -106.078109113242 66.8129279212515 -1.58768837728934 0.114394661904456 PLCD1 other 0.123531369774814 1 1 3.43845839436951 -1.58768837728934 4.44042444371776e-10 222.515 47.2547531739152 4.70883847770955 5.4405928784714e-06 -150.7685 71.3009347627222 -2.11453749521985 0.0360487420128208 ENTPD5 other 5.10293577072045e-06 1 0.0565332006001963 4.70883847770955 -2.11453749521985 0.533596344203208 15.0271650629164 17.2386688323856 0.871712613603055 0.384731009838107 -6.87914003095348 41.1164463119456 -0.167308720670125 0.867348072272545 MITF og 1 1 1 0.871712613603055 -0.167308720670125 1.66394802463789e-07 13.8975719569063 3.08800170436227 4.50050656943415 1.33476534932017e-05 -3.75028139572279 4.64286930957532 -0.807750799271545 0.420488099514434 HEATR4 other 0.00162634279928108 1 0.13386361688332 4.50050656943415 -0.807750799271545 2.13994767519254e-13 2238.80017322246 413.5445900157 5.41368507114908 2.34141617845913e-07 -2509.6864251466 898.533596060592 -2.79309136146909 0.00588802310204036 NAP1L1 other 2.76866430216411e-09 1 0.00266219019490803 5.41368507114908 -2.79309136146909 0.207561256542719 2.73201162194496 2.05890981968812 1.3269214590267 0.186461283917971 -1.14877798666895 4.3965780341138 -0.261289115706666 0.794212005302905 LILRA5 other 1 1 1 1.3269214590267 -0.261289115706666 3.37478120303717e-05 43.9538302811453 35.432301605285 1.24050169731535 0.216652340251135 -271.0584931075 79.1645162198574 -3.42398976272034 0.000788495577225317 CMC1 other 0.262895455716595 1 1 1.24050169731535 -3.42398976272034 0.448829814171314 9.07062285434033 8.80571997322217 1.03008304623855 0.304545288743823 -0.274460519862703 15.6665269249893 -0.0175189128501044 0.986044747839399 SLIT1 other 1 1 1 1.03008304623855 -0.0175189128501044 0.000494777558487255 113.462714273087 31.296589727354 3.62540184926019 0.000389395422570263 -39.7662493965335 88.5698932167612 -0.448981566447322 0.654064078517721 LYPD6 other 1 1 1 3.62540184926019 -0.448981566447322 1.22570478405343e-07 26.5102889508431 4.45898810731387 5.94535986928503 1.7810640874493e-08 41.0021453667334 20.0617614988902 2.043795873508 0.042677629184449 AKR1C1 other 0.00121038347425276 1 0.000214440116128895 5.94535986928503 2.043795873508 0.0727753066348002 11.2670716411425 5.22296264163145 2.15721850111168 0.0328715773033735 -4.00554871545015 23.4246904413752 -0.170996868687542 0.86449836693761 VSTM2B other 1 1 1 2.15721850111168 -0.170996868687542 0.768994902266938 5.78046173578451 7.96986245113881 0.725290024918628 0.469346965930446 4.7114151346729 25.0308587556622 0.188224270715728 0.850942376816202 FOXD3 other 1 1 1 0.725290024918628 0.188224270715728 3.01248559215497e-10 158.753061329492 40.8604207875561 3.88525272793664 0.000152565324317792 -242.25751183371 91.1400049058457 -2.65808096108817 0.00870515460648776 SPATA21 other 3.49116955274839e-06 1 1 3.88525272793664 -2.65808096108817 7.11528869803273e-07 283.675628044092 65.5308327907164 4.32888788320541 2.706437659042e-05 -571.719462958215 268.661076657226 -2.1280323524038 0.0349471667961221 RNF220 other 0.00656812299715401 1 0.26352583486092 4.32888788320541 -2.1280323524038 0.0177440189826365 68.881506673778 35.3569887255131 1.94817231774249 0.0531891648567733 -55.3974459321239 63.3900554695955 -0.873913826415483 0.383508516803989 SHTN1 other 1 1 1 1.94817231774249 -0.873913826415483 7.43529926388764e-09 26.7599932493811 5.15431258399068 5.19176763405807 6.36831885333522e-07 -18.0712157734397 18.4931065303861 -0.977186593488059 0.329980086858068 ZNF546 other 7.98253728970977e-05 1 0.00704590797933009 5.19176763405807 -0.977186593488059 3.56062974201683e-13 338.988139974264 56.5309556922667 5.99650467293687 1.35144993956187e-08 -95.7440679840197 117.414558455663 -0.815436085978843 0.416065982216629 TSPYL4 other 4.58110622607886e-09 1 0.000163538957186382 5.99650467293687 -0.815436085978843 0.179728208060183 -271.848188405799 192.3582908721 -1.41323873888312 0.159603589415311 -556.80084541063 299.906206741037 -1.85658326801958 0.0652809398841485 MT1X other 1 1 1 -1.41323873888312 -1.85658326801958 0.0346164115821755 118.620143138459 46.4522959560577 2.55359053190115 0.0116206356777189 36.4351589133335 67.3375009268157 0.541082731195093 0.589222380823842 GCNT1 other 1 1 1 2.55359053190115 0.541082731195093 0.425589777388076 44.1388694301466 42.0424379512964 1.04986465060087 0.29540404133228 -68.2818658057442 149.170936938941 -0.45774242092274 0.647774415096605 SESTD1 other 1 1 1 1.04986465060087 -0.45774242092274 0.000474562691453622 307.366747554599 197.573818504235 1.55570586164488 0.121791570894367 -568.780026517899 272.377049864821 -2.08820833767081 0.0383933425885249 FNBP1 other 1 1 1 1.55570586164488 -2.08820833767081 2.11077250595463e-09 163.458299321314 27.3701521625366 5.97213703272906 1.64766722245402e-08 1.51971919677207 77.0337426057076 0.0197279678406728 0.984286773265373 DYNC2H1 other 2.34359071336143e-05 1 0.000198560376977934 5.97213703272906 0.0197279678406728 3.54168862574772e-30 19562.0226562217 1472.43431982899 13.2854976230747 2.2559283549245e-27 -10049.213276199 6238.01519308212 -1.61096325756683 0.109222255937742 BCAM other 5.13261515643359e-26 1 3.26793781494364e-23 13.2854976230747 -1.61096325756683 4.13991487469888e-09 169.012886006199 29.7943500429395 5.67264886673542 6.83269374331264e-08 -176.695901733441 100.658387790892 -1.75540166707727 0.0811919830438612 RSBN1L other 4.51374918788419e-05 1 0.000800791706716241 5.67264886673542 -1.75540166707727 0.000173429954652634 129.711859134262 30.4190195960669 4.26416961679573 3.51035100569032e-05 80.7632457813648 96.5805366103247 0.836226931594114 0.404339914899236 WDR86 other 1 1 0.337520249197125 4.26416961679573 0.836226931594114 0.0180728131952294 94.3324662142656 52.3902318578527 1.80057355863994 0.07375287274024 -223.391344713258 188.539096495126 -1.18485422316126 0.237924340997791 EPOR other 1 1 1 1.80057355863994 -1.18485422316126 0.0681090777614603 18.9040159532227 10.2245492760936 1.8488850161271 0.0663550864274534 43.4813129055219 20.938004990022 2.07666933531838 0.039461433661079 CIDEC other 1 1 1 1.8488850161271 2.07666933531838 0.156592584824695 32.5142625094093 16.7928889585409 1.93619231269153 0.0547370254454886 24.275068341191 39.9848410124165 0.607106786635786 0.544704083904173 PCDHB13 other 1 1 1 1.93619231269153 0.607106786635786 7.48880916704609e-05 46.0072693255062 11.7547740004829 3.91392206465357 0.000135985717815851 -34.5371447943218 38.589639884252 -0.894984894855575 0.372191861341213 MAGI2 other 0.558665163861639 1 1 3.91392206465357 -0.894984894855575 1.05413802695801e-07 366.153185907582 102.633677549887 3.56757347732773 0.000482311870889857 -321.05029584955 150.86355582985 -2.12808384426285 0.0349428259533098 CHP1 other 0.0010470753021774 1 1 3.56757347732773 -2.12808384426285 0.0227045956667998 125.521183085013 45.1362640829186 2.78093868944096 0.00608830930471238 147.837593888804 87.5321710904596 1.68895152544568 0.0932265089104829 FPR3 other 1 1 1 2.78093868944096 1.68895152544568 0.802204628992022 -48.6133015716551 73.3937546819861 -0.662362918783699 0.508748340436186 -37.4730025737907 128.387139557308 -0.29187504841218 0.770782770616884 C11orf96 other 1 1 1 -0.662362918783699 -0.29187504841218 4.00288700484038e-05 45.1985470832423 12.6694020100979 3.56753594583372 0.000480642988963903 -7.57658461389073 19.4018806117798 -0.390507743321059 0.696700781060066 KCNJ11 other 0.30794209728237 1 1 3.56753594583372 -0.390507743321059 0.17471650623425 -55.4502106404085 44.3622426548174 -1.24994155664912 0.213451868456157 -170.358295755494 94.7777152428791 -1.79745096533432 0.074466661667186 CDHR4 other 1 1 1 -1.24994155664912 -1.79745096533432 0.0172726172504018 1035.76913198529 432.041377180068 2.39738410877622 0.0177105019461711 2141.13451363953 880.274457052516 2.43234879358971 0.0161474585817431 COL4A1 other 1 1 1 2.39738410877622 2.43234879358971 0.0238286835061289 -3.07458252228255 4.461700992096 -0.689105461735163 0.49182145442874 -23.5350685300244 9.01852733978791 -2.60963543639686 0.00998233934387142 PLEKHG7 other 1 1 1 -0.689105461735163 -2.60963543639686 0.42010662865796 13.561108653988 60.4042332295361 0.224505931603432 0.8226631930859 -205.759090238966 187.414064825314 -1.09788499828308 0.273979497022148 GJA4 other 1 1 1 0.224505931603432 -1.09788499828308 1.94109957044131e-12 123.95287103766 17.2012298052095 7.20604703508587 2.31573469051601e-11 -95.1617919123885 84.8959385556123 -1.12092278537037 0.264043318728486 HSPA14 essential 2.44287380940039e-08 1 3.06626430371225e-07 7.20604703508587 -1.12092278537037 0.000197903080012317 96.7711917618989 22.7483010553154 4.25399644248542 3.85073015936578e-05 52.0059650885359 103.285340615346 0.503517389580154 0.61540335350322 SIRT7 other 1 1 0.368264705561977 4.25399644248542 0.503517389580154 4.2200588196057e-17 391.383059794906 51.3074768662948 7.62818761902546 3.50853138474236e-12 -186.654080651713 113.189656562102 -1.64903831605236 0.101414405503437 IFT140 other 5.82790122987547e-13 1 4.7200272718939e-08 7.62818761902546 -1.64903831605236 0.81149830741397 2.5854650200989 14.8166094641313 0.174497750403553 0.861709597755854 -12.2893215838295 29.4190156261792 -0.417733949360752 0.676738997665961 SBK2 other 1 1 1 0.174497750403553 -0.417733949360752 0.343407502295051 4.17652625276531 3.70917269386849 1.12599940673277 0.261906148904146 -0.74992389032087 6.58206564081097 -0.11393442898398 0.90943721771753 CYP26C1 other 1 1 1 1.12599940673277 -0.11393442898398 0.210358222196724 22.0014118702904 22.94414647152 0.958911759807678 0.33908700971581 -77.9018896077954 73.041244691125 -1.06654657840546 0.28782446175731 TLR5 other 1 1 1 0.958911759807678 -1.06654657840546 3.02595927055961e-19 784.186190516584 78.8772239774368 9.94185838412497 2.82180115025143e-18 306.117524811265 179.919752203223 1.70141144072663 0.0908970506537044 USP7 essential 4.25691950182326e-15 1 4.01514085669276e-14 9.94185838412497 1.70141144072663 5.62771036820733e-12 5.09380166023784 0.780376791360022 6.52736180346994 9.72208825843766e-10 -12.6018245066364 5.59419649228837 -2.25266032825412 0.0257315065512869 NANOS3 other 6.97554700139299e-08 1 1.22741364262775e-05 6.52736180346994 -2.25266032825412 0.000202987309236243 19.7300835750399 5.60617224361798 3.51935023000773 0.000569055380001353 -10.433415749201 15.7543947295001 -0.662254306074003 0.508798098318226 NHLRC1 other 1 1 1 3.51935023000773 -0.662254306074003 0.606928247529499 10.9215247982511 17.4614273900493 0.625465751126104 0.532579346832416 -14.8123848480495 30.621005097591 -0.48373281023407 0.629253827637033 COX8C other 1 1 1 0.625465751126104 -0.48373281023407 0.115476067696168 21.8596981320881 12.1868406161272 1.79371330278665 0.075315861717732 0.777622581721171 27.1378137863335 0.028654577256801 0.977186524494891 PLEKHN1 other 1 1 1 1.79371330278665 0.028654577256801 1.13638582200019e-07 29.1094041132008 4.95210035162445 5.87819350301574 2.43370201160257e-08 -6.23885568641238 19.9186326493287 -0.313217066464783 0.754534125764942 ZNF385C other 0.00112547651810899 1 0.000291314130788828 5.87819350301574 -0.313217066464783 1.0794488561112e-10 109.342739302286 15.6017060078646 7.00838352210765 6.82727597236427e-11 -57.9490977831243 64.1541254324582 -0.903279366564405 0.367770326653973 ZNF286A other 1.27677210700833e-06 1 8.93758697542207e-07 7.00838352210765 -0.903279366564405 0.9892230296497 68.4434623082054 589.142386173642 0.116174737914771 0.907703521991688 181.304036024016 1311.90986025197 0.138198546651059 0.89030949700143 ISG15 other 1 1 1 0.116174737914771 0.138198546651059 0.000876588271416402 131.153891278842 34.6977877979686 3.77989202200726 0.000245866029416755 59.0484384602491 54.066662327891 1.09214136619246 0.276958785974398 EXD3 other 1 1 1 3.77989202200726 1.09214136619246 0.0447618949531016 19.7863085375424 11.965617866236 1.65359689392844 0.100233327439288 -19.8633251940351 19.7395111395557 -1.00627239720396 0.31585287019073 TCL6 other 1 1 1 1.65359689392844 -1.00627239720396 0.000495702945301725 104.80091212068 31.7611208975035 3.29966037593207 0.00124252422485895 -196.005700754255 138.307995813544 -1.41716825264747 0.15877203219575 C17orf97 other 1 1 1 3.29966037593207 -1.41716825264747 1.06803138052412e-14 29.7943290734823 4.41663370954104 6.74593616607125 2.94240459988533e-10 -29.8770650719533 12.5699088874083 -2.376872047329 0.0186966335263002 ZKSCAN4 other 1.42357902710059e-10 1 3.77539934211287e-06 6.74593616607125 -2.376872047329 3.74557370561035e-05 12.4540961414411 23.4268064853793 0.53161732262627 0.59580456674974 -228.135892229278 53.483019974788 -4.26557610876914 3.57915091496608e-05 DHRS4L2 other 0.289645214654848 0.516113561938108 1 0.53161732262627 -4.26557610876914 0.00107988045512185 440.444689038907 125.116004121909 3.52029056658292 0.000608483199882397 175.681956538282 279.547451800752 0.628451289420086 0.530892828938983 SAMD11 other 1 1 1 3.52029056658292 0.628451289420086 0.490645168871959 4.19471314209473 4.06186377985674 1.03270650357523 0.303767537307261 0.300075050033355 9.04501062706393 0.0331757542810938 0.973588208711071 PERM1 other 1 1 1 1.03270650357523 0.0331757542810938 2.21804041252291e-13 41.1272104992547 8.02084304398548 5.12754211417893 8.59091925115074e-07 -32.9016499867565 15.5329569820061 -2.11818329406763 0.0357441449067157 VMAC other 2.86836986147463e-09 1 0.00942423841851236 5.12754211417893 -2.11818329406763 3.5940136119238e-05 111.852624503946 24.0129269956884 4.65801709737548 6.98320051039571e-06 127.119078706175 78.9393109913296 1.6103393494293 0.109426193236445 HAPLN4 other 0.278643875332452 1 0.071843166850951 4.65801709737548 1.6103393494293 0.00276553709229455 9.34032732519674 2.7124154102299 3.44354603279778 0.000739664143465529 6.96899339131541 6.10285136321322 1.14192415586641 0.255257959784736 ERC2 other 1 1 1 3.44354603279778 1.14192415586641 0.317602611582956 21.3094530101093 14.857039422772 1.43430009194479 0.153501072809005 8.64272930752245 24.6597468999764 0.350479238192453 0.726454912744038 B3GLCT other 1 1 1 1.43430009194479 0.350479238192453 0.0853011957462867 -79.1315507737973 191.81454335577 -0.412541976168238 0.680508617333202 -613.80578757685 288.021812268236 -2.13110869188341 0.0346471879146499 SPRY4 other 1 1 1 -0.412541976168238 -2.13110869188341 0.880411712622632 -7.39099426653614 17.0631403351897 -0.433155569335238 0.665503921947457 9.47246888547043 57.4792029090654 0.164798194930718 0.86931754904843 TRPV2 other 1 1 1 -0.433155569335238 0.164798194930718 0.071992107464467 289.051056625629 343.84589673848 0.840641285434541 0.401869360731567 -2224.52821480019 1244.60363538851 -1.78733867678748 0.0758754242658053 C2orf88 other 1 1 1 0.840641285434541 -1.78733867678748 0.000319118153926656 151.877843920737 50.9006366403917 2.98381030071864 0.00344462082291505 -86.3222158797469 79.635688102004 -1.08396396059488 0.280535936673665 TMEM203 other 1 1 1 2.98381030071864 -1.08396396059488 0.0648722187518479 18.8444386050528 8.60846531552518 2.18905901509149 0.0300691889045422 1.44776455572659 18.2056170856784 0.0795229598048332 0.936717941691893 SLC18A3 other 1 1 1 2.18905901509149 0.0795229598048332 0.103604992172566 19.9663639048885 9.48156482263956 2.10580893326953 0.0369324475146356 26.3215920838871 37.6760602753761 0.698629100057208 0.485895200210285 KBTBD12 other 1 1 1 2.10580893326953 0.698629100057208 0.014623632171325 144.339183854268 948.93675970555 0.152106220333434 0.879307555114623 -4376.14974728767 1669.77432090554 -2.62080311842048 0.00967528019299877 THSD4 other 1 1 1 0.152106220333434 -2.62080311842048 0.207271422401107 44.4185748156809 52.2225990056197 0.850562317109132 0.396333046643197 -241.110461528468 196.32081843719 -1.22814515265281 0.221266203936444 DNAJB13 other 1 1 1 0.850562317109132 -1.22814515265281 0.161630716654065 -0.369362169721793 1.79187267921513 -0.206131927790528 0.836996119009056 -6.86849208331251 4.00656903509079 -1.71430768399499 0.088750239494565 GABRD other 1 1 1 -0.206131927790528 -1.71430768399499 0.613577934867032 -807.057631517649 970.693026554125 -0.83142415721542 0.407055615872753 -2354.04716429546 3002.13589029763 -0.784124120398189 0.434203775994472 AMY1C other 1 1 1 -0.83142415721542 -0.784124120398189 8.23304122193778e-06 67.4418033524785 14.7049226144402 4.58634194281653 9.91540115750201e-06 0.420777443690302 35.7537264896269 0.0117687716778944 0.990626849663017 NHEJ1 other 0.0686306316260734 1 0.100730560359063 4.58634194281653 0.0117687716778944 7.48624445257915e-08 332.999662115465 62.2771075670098 5.34706371449828 3.71206344058227e-07 103.426103116217 110.101193576098 0.93937313263305 0.349216904493572 FANCA ts 0.000753041329484937 1 0.0041667912120536 5.34706371449828 0.93937313263305 3.25127876407537e-08 205.639217210517 38.5069032865735 5.34032081676686 3.27344087385391e-07 7.06233777752266 58.8427447306578 0.12002053625896 0.904623316897233 SECISBP2 other 0.000335336891726734 1 0.00368654911213427 5.34032081676686 0.12002053625896 2.37234276422778e-05 229.240101005095 63.5678582982715 3.60622659221049 0.00041919261863695 -73.5241726164545 97.1386151486259 -0.75689953479324 0.450266499915078 SEMA4D other 0.188458909190255 1 1 3.60622659221049 -0.75689953479324 0.0079901079681981 39.9322898414102 13.6946546038533 2.91590339417356 0.00407662047933906 22.2923190404118 28.2498005998921 0.78911420849098 0.431258455002428 LIN28B other 1 1 1 2.91590339417356 0.78911420849098 0.0309626287137175 22.9123689000607 9.60210664769073 2.38618146420723 0.0182469086792842 14.6525526566698 18.2561522812637 0.802609029050866 0.423445719895397 FAM69C other 1 1 1 2.38618146420723 0.802609029050866 2.92266535172238e-05 43.5578835978837 9.61432713078695 4.53051815330923 1.1589475370422e-05 55.148544973545 38.8936449929436 1.41793202934697 0.158192346016794 DNAH17 other 0.229516910070758 1 0.116972574913669 4.53051815330923 1.41793202934697 7.23030800313003e-17 300.992090109473 44.1363468665859 6.81959680576426 2.16862612029268e-10 -446.809902479838 114.697497006652 -3.89555059299963 0.000147929353958942 MCRS1 essential 9.9648104899138e-13 1 2.79535906905726e-06 6.81959680576426 -3.89555059299963 0.508635424108129 3.99837167533335 6.04474646661221 0.661462262713269 0.509330691776626 -8.19681044746196 13.5480709468795 -0.605016793874254 0.546082028772186 TMEM72 other 1 1 1 0.661462262713269 -0.605016793874254 6.63157044588483e-07 39.356462923902 8.2769996944077 4.7549189775243 4.90490123630598e-06 -10.1580180418589 12.5285995679146 -0.810786392109887 0.418874399421357 FANCM other 0.00614481317515688 1 0.0511532149934351 4.7549189775243 -0.810786392109887 1.00504373856833e-73 119.700437381179 3.40498956290715 35.1544212308775 6.88055278320668e-75 68.0297732948968 18.8380121930656 3.611303177728 0.000413252362685787 ZNF70 other 1.46917293703919e-69 1 1.00579920584915e-70 35.1544212308775 3.611303177728 0.159282570553214 35.4504541141385 55.8114585011873 0.635182363374078 0.526452246742983 -102.356432153992 83.4776531041743 -1.22615368721805 0.222409505659655 CARD9 other 1 1 1 0.635182363374078 -1.22615368721805 4.77379309461102e-12 17.4795188219434 2.29802327240148 7.60632802629407 2.873254769112e-12 -8.70753117047845 16.066867222648 -0.541955755892737 0.588653147447379 ZFP69B other 5.93048316143527e-08 1 3.87286010328606e-08 7.60632802629407 -0.541955755892737 2.45602387209697e-13 27.2771958933941 3.43008411311605 7.95234023244236 4.09555413460902e-13 -26.6324827096579 23.9817875953703 -1.11052950509825 0.268547937130797 ZFP69 other 3.17269163797487e-09 1 5.59206961539515e-09 7.95234023244236 -1.11052950509825 0.000254687817651793 6.09082271406213 7.40179458257422 0.822884591853107 0.411871256917606 -112.848871003801 29.0353443196265 -3.8866035050778 0.000151796416712205 TMEM220 other 1 1 1 0.822884591853107 -3.8866035050778 0.572500660516402 -196.188915547025 209.326330270896 -0.93723954981263 0.350152027823996 -484.118938781695 581.410483905161 -0.83266289856009 0.406367519676238 HIST1H1C other 1 1 1 -0.93723954981263 -0.83266289856009 6.62219643470171e-18 554.101848462664 56.11576671895 9.87426316810079 6.2613839944036e-18 -63.4535139092259 298.367042308841 -0.212669312998535 0.831881547177446 PLSCR3 other 9.2220707549656e-14 1 8.89257487502248e-14 9.87426316810079 -0.212669312998535 4.78071262716364e-12 710.149241674324 95.7441864018702 7.41715260594091 1.07391976297646e-11 -123.542872317071 332.310741519858 -0.371769121130525 0.710630877538768 EIF4EBP1 other 5.93860122546268e-08 1 1.43078330021353e-07 7.41715260594091 -0.371769121130525 0.362320278532627 1.41256027352114 7.88748032704031 0.1790889124222 0.858111182463169 -16.6699655798903 15.268007481959 -1.09182325195923 0.276673091175078 P2RX2 other 1 1 1 0.1790889124222 -1.09182325195923 1.4565059413273e-12 144.001905888538 17.7954390730995 8.0920681584204 1.74037415805444e-13 115.220601121626 32.9784750144351 3.49381228426096 0.00062398580751354 CCDC157 other 1.84087785924358e-08 1 2.38657508294005e-09 8.0920681584204 3.49381228426096 2.22313667272125e-06 91.6164666269329 23.9067557860173 3.83224170803292 0.000184969936810173 -94.0339759267251 43.7691841803686 -2.14840595472879 0.0332551303933289 FAM122A other 0.0196391893668195 1 1 3.83224170803292 -2.14840595472879 1.87118866015889e-06 68.060917694336 14.7734495807434 4.60697532572561 8.66389331100818e-06 -146.965375600356 108.884056799239 -1.34974191741709 0.179132212723393 PALM3 other 0.0166573214527344 1 0.0884756784920155 4.60697532572561 -1.34974191741709 0.377279746633259 -904.922412567366 653.75482677079 -1.38419232334729 0.168289281260932 -537.094548790277 1188.66590377739 -0.451846517245491 0.652011201128662 DMBT1 other 1 1 1 -1.38419232334729 -0.451846517245491 0.160180075509255 47.4683032490975 24.6453397516463 1.92605594921558 0.0563498617506722 33.0139865910263 38.1958008068837 0.864335500070901 0.3890461074364 LCN10 other 1 1 1 1.92605594921558 0.864335500070901 1.6556599839583e-11 1006.63159665279 187.809245037062 5.35986179196953 3.05709162528099e-07 -434.144411504982 398.475118147229 -1.08951448091315 0.277662770016999 LDLRAD2 other 2.02007074642752e-07 1 0.00345084502661718 5.35986179196953 -1.08951448091315 2.45508711385238e-12 49.2904829030152 14.4746435422216 3.40529856636802 0.000850904649363053 -83.9012323925415 27.9901583538592 -2.99752617801726 0.00319311619381548 PMS2CL other 3.08088881917335e-08 1 1 3.40529856636802 -2.99752617801726 3.84048423265006e-07 500.817671203283 91.2660162307752 5.48744967608662 2.8451717161552e-07 -93.8358176712035 352.273079281178 -0.26637237753926 0.790474822882399 CYHR1 other 0.00363156189039389 1 0.00321760469379992 5.48744967608662 -0.26637237753926 0.0665349838997163 106.134968540954 83.3279228891316 1.2737023180353 0.204752238334904 1003.28463217297 447.035369487281 2.24430705186409 0.0262860951003346 COL14A1 other 1 1 1 1.2737023180353 2.24430705186409 0.705917526033387 12.016878111344 14.5639214415977 0.82511280766876 0.41055156032194 8.61282815795215 32.5100604078373 0.264928088410314 0.791410166345976 DNER other 1 1 1 0.82511280766876 0.264928088410314 1.29046018227537e-10 10.2939762772308 1.42025763172153 7.24796406462761 1.83791702727353e-11 3.92704860841927 5.83301549980168 0.673245015130303 0.501787595567425 CPSF4L other 1.52016209472039e-06 1 2.43781314497561e-07 7.24796406462761 0.673245015130303 0.00197851183804506 20.0446130753836 12.5088658750882 1.6024324887281 0.111625044596563 -53.099608072048 27.8549037842625 -1.9062929990104 0.0589453409657857 KLHL17 other 1 1 1 1.6024324887281 -1.9062929990104 0.113540397885282 -3.18159517563286 2.35006333624429 -1.35383379952536 0.177772913196048 -7.20873224080952 3.46257969103703 -2.08189641366796 0.0390062248556787 ANKRD19P other 1 1 1 -1.35383379952536 -2.08189641366796 7.72263330574625e-05 28.0040860800871 9.08309821437457 3.08309845596175 0.00242819303026341 -46.9774433245558 32.0845333884803 -1.46417723317811 0.145183852186638 RINL other 0.574950049612808 1 1 3.08309845596175 -1.46417723317811 0.361905460263523 -20.8329721057224 20.7323631349291 -1.0048527497873 0.316596835577195 -95.9775569754459 78.8329763281265 -1.21747980915954 0.225346352591297 TPRG1 other 1 1 1 -1.0048527497873 -1.21747980915954 0.343969203245572 22.6141108146288 29.3060040109905 0.771654532161667 0.441509246158084 -128.147054562139 114.599421307115 -1.11821729202905 0.265226866273053 MORN2 other 1 1 1 0.771654532161667 -1.11821729202905 6.32632310230215e-12 94.9150491980052 16.6771301794838 5.69132987369552 6.30159137560688e-08 -85.315406389001 39.5121972326117 -2.15921695993624 0.0324019429437008 RILPL1 other 7.82882483909891e-08 1 0.000740436986633808 5.69132987369552 -2.15921695993624 3.60687461222823e-17 54.5922737879181 6.57381662086044 8.30450207793788 5.63752652598096e-14 -37.8347420274825 27.7773404317885 -1.36207215807401 0.175230730684787 ZNF490 other 4.98470071409941e-13 1 7.76907530545436e-10 8.30450207793788 -1.36207215807401 0.0841426515738487 16.2254594441158 11.1600170657194 1.45389199215081 0.148011187017509 -87.4082737207005 72.8557002211484 -1.199745160027 0.232080839429211 NWD1 other 1 1 1 1.45389199215081 -1.199745160027 0.000880204036680638 541.035990481858 295.285487835082 1.83224713970376 0.0687973442829592 -1406.28826378856 657.698146309207 -2.13819709190334 0.0340382105831599 ARL4C other 1 1 1 1.83224713970376 -2.13819709190334 0.000394535566078104 85.6752652859315 22.1226010728722 3.87274828143923 0.000159861227992875 -21.7912264128257 161.529800052485 -0.134905301719839 0.892866405427732 TMEM221 other 1 1 1 3.87274828143923 -0.134905301719839 0.0580006010939469 7.13076108568149 7.13074390292641 1.00000240967216 0.318909144709177 -20.2061095307485 16.439808395585 -1.22909641308076 0.220947566694112 RAB42 other 1 1 1 1.00000240967216 -1.22909641308076 0.641864387546666 -49.0272106125388 65.0179457966251 -0.754056591789212 0.451966671602969 -91.4035561593486 101.428375413947 -0.901163562822677 0.368908526635735 WNT7B other 1 1 1 -0.754056591789212 -0.901163562822677 1.6771444630132e-07 294.747724277439 50.2148050354065 5.86973750210943 2.84980420049034e-08 144.165537744812 165.066972193109 0.873376035371604 0.38390225022152 C11orf95 other 0.0016387378548102 1 0.000340067135244512 5.86973750210943 0.873376035371604 0.00242424035877196 12.6753817786393 5.74075757472211 2.20796325461503 0.0288509808321558 -20.5750319133847 12.5321478943925 -1.64178017102647 0.102848463584602 PRSS45 other 1 1 1 2.20796325461503 -1.64178017102647 0.146212295473796 17.7792804737912 9.70525065166192 1.83192388449511 0.0688947122011919 -1.246202962755 17.4942301401205 -0.0712350845263559 0.943303084651431 MESP2 other 1 1 1 1.83192388449511 -0.0712350845263559 2.33660324380273e-07 17.8583718530915 3.15738406946943 5.65606573675164 8.58368457142679e-08 12.0688427283633 6.1713254481505 1.95563219437409 0.0525287390922145 EYS other 0.0022529528476746 1 0.00100042843679979 5.65606573675164 1.95563219437409 2.63411824110002e-39 642.76141812206 36.1289737166785 17.7907466501142 6.89587949955146e-39 -167.339393889707 240.214806754931 -0.696623976474636 0.487109142412743 C6orf132 other 3.83580298268985e-35 1 1.00417797272468e-34 17.7907466501142 -0.696623976474636 4.81383217788996e-05 153.314622271733 78.2451290500142 1.95941426812313 0.0519822516565872 -283.510046622932 127.61811522353 -2.22155017825132 0.0278634809797433 MAPK12 other 0.367247256851225 1 1 1.95941426812313 -2.22155017825132 0.320134912989864 -2.93646063125743 1.96609663868074 -1.49354847238222 0.137422538313767 -2.27489182080435 4.84931656726777 -0.469115964950517 0.63967706933034 TMEM215 other 1 1 1 -1.49354847238222 -0.469115964950517 0.137590772144261 3.70986460348168 4.50225413405098 0.824001598537856 0.411188671247387 -7.65761000967103 6.89168344776072 -1.1111378036609 0.268207767085596 NUTM2G other 1 1 1 0.824001598537856 -1.1111378036609 1.3146585423111e-12 10470.779811541 1461.37936215382 7.16499772934315 6.27040391164202e-11 762.113930120088 3254.2184024988 0.23419261888965 0.815224815929356 AGRN other 1.66370038529469e-08 1 8.21924544738037e-07 7.16499772934315 0.23419261888965 0.228196733206547 33.9020767077116 74.8297357787099 0.453056212946795 0.651319633841785 -145.491125064558 117.073535667723 -1.24273281946049 0.216369187319352 FAM166A other 1 1 1 0.453056212946795 -1.24273281946049 1.1452336678498e-10 27.6893612754437 4.39834188391887 6.29540904418573 3.0446919209935e-09 -5.18902703967382 9.69515989864511 -0.535218304176601 0.593270931494206 TMPPE other 1.35297905519776e-06 1 3.77815820476084e-05 6.29540904418573 -0.535218304176601 4.82015696081633e-07 107.119901780097 22.5765940834995 4.74473259269817 4.70561604030776e-06 -46.500605522364 73.9039879238839 -0.629202927049842 0.530142465713786 ZNF626 other 0.00451889715076531 1 0.0491783932372564 4.74473259269817 -0.629202927049842 0.000145287442247343 35.2006612410986 8.6746011656705 4.05789967386677 7.80683816947169e-05 -40.3752119362497 49.0676134655157 -0.822848495874474 0.411850190616329 SMTNL2 other 1 1 0.72244480420291 4.05789967386677 -0.822848495874474 3.41240012859504e-11 161.737179521977 23.9633307612161 6.74936139444118 2.79749897695711e-10 -53.3823805620547 67.6857085660662 -0.788680235354995 0.431503544643989 ZC3H6 other 4.11433083504704e-07 1 3.59226843631062e-06 6.74936139444118 -0.788680235354995 0.00028488901562628 289.975464443745 88.4637168192941 3.27790279302961 0.00129101525017899 -447.841931688238 291.306039643576 -1.53735889663046 0.12624431290505 LAMTOR4 essential 1 1 1 3.27790279302961 -1.53735889663046 6.02003638624049e-10 340.288925771189 69.3162174831595 4.90922525964235 2.44707497283416e-06 -54.0119384192754 130.126599018948 -0.415072236010798 0.678706791734292 PRKAR1B other 6.87427954944802e-06 1 0.0260858192104121 4.90922525964235 -0.415072236010798 6.70977828454434e-05 11.8039429847577 3.00403785570529 3.92935893345671 0.000127975400230778 -1.52292853975734 7.20483420723135 -0.211375931208633 0.832871601062007 NUTM2B other 0.503099175775135 1 1 3.92935893345671 -0.211375931208633 0.0350382341985535 11.3468278450349 10.7144023569623 1.05902573629425 0.291235615620754 -22.1081420533535 16.4651875677696 -1.34272032810789 0.181325590874449 NCR3LG1 other 1 1 1 1.05902573629425 -1.34272032810789 0.00782342243571676 57.9354521462298 26.2124905189169 2.21022310353986 0.0285363319259435 -77.9122454051622 71.5903737042798 -1.08830616986295 0.278127780387415 DCUN1D3 other 1 1 1 2.21022310353986 -1.08830616986295 0.418635706540038 11.0571907691407 33.147926244686 0.333571116561575 0.739159930895166 105.634358334389 80.8530703812195 1.30649779700792 0.193343860692634 POTEE other 1 1 1 0.333571116561575 1.30649779700792 2.79620039741444e-14 56.0271042010309 8.22259911852437 6.8137949319224 2.23626731775435e-10 -75.8277132514981 32.3638922245669 -2.34297261668479 0.0204620405993189 ZNF793 other 3.69713616546137e-10 1 2.88210131912181e-06 6.8137949319224 -2.34297261668479 0.00418795585403516 1500.37233955802 778.460609637781 1.92735807179267 0.0562790439998935 -1834.46201310175 1217.9267372781 -1.50621704652081 0.134617667939373 TUBB4B other 1 1 1 1.92735807179267 -1.50621704652081 0.000635345869077157 33.5369847485925 10.0201270080998 3.34696204164706 0.00102679283995079 -15.0870699338661 23.8385561831721 -0.632885222491631 0.527747249200924 AGAP4 other 1 1 1 3.34696204164706 -0.632885222491631 4.24667630911874e-05 392.599889588016 125.06764560756 3.1391003459034 0.00204854425165433 -374.073650113737 228.334451854044 -1.63827073433865 0.103503921489044 COMMD6 other 0.325889939961772 1 1 3.1391003459034 -1.63827073433865 0.380761317676965 -21.3444532480894 25.469401201035 -0.838042994399966 0.403296988804491 -78.3703450725385 56.2199968020647 -1.39399412185061 0.165314575026547 PLA2G2A other 1 1 1 -0.838042994399966 -1.39399412185061 8.26102301866332e-05 20.1736431319161 6.62926391463097 3.04311962711158 0.00275660598452334 -21.7218972226447 11.8920971991113 -1.82658254965053 0.0697116242302121 HYKK other 0.612554856833885 1 1 3.04311962711158 -1.82658254965053 2.55393253864814e-06 31.9763067385674 9.10561625594 3.51171253430627 0.000588443011975015 -23.6599220215453 14.2801947991802 -1.65683468287867 0.0996431280336474 C15orf62 other 0.0223954344314055 1 1 3.51171253430627 -1.65683468287867 0.268364123849398 -2.63783026830702 9.10488040220675 -0.289716081022623 0.77246829101781 -38.5314026651661 24.2862499668395 -1.58655217325758 0.114902846549389 RUFY4 other 1 1 1 -0.289716081022623 -1.58655217325758 5.15575758143617e-23 52.6233998806129 5.15771430763041 10.202852802987 7.25868554933715e-19 -39.8612054610892 21.0584676610717 -1.89288252605273 0.0603127073555505 ZNF383 other 7.38356043237473e-19 1 1.03545149361294e-14 10.202852802987 -1.89288252605273 0.09358315539129 218.154686457639 116.402148887184 1.87414655608353 0.0632826680520649 4.55182621747821 259.205805699075 0.0175606646047221 0.986017790498146 HES4 other 1 1 1 1.87414655608353 0.0175606646047221 0.273496958397474 3.73105325795896 9.72332556565005 0.383721930605696 0.701703699053871 -21.0294644451056 20.04400878291 -1.04916459940069 0.295714721321268 IGFL1 other 1 1 1 0.383721930605696 -1.04916459940069 2.08366079322478e-10 29.7421395211399 5.07561201128278 5.85981344811719 2.71851600663515e-08 -24.1408377178222 15.8551541875184 -1.52258612135267 0.12991305793258 ZNF669 other 2.43246561001061e-06 1 0.000324672366672436 5.85981344811719 -1.52258612135267 2.67337865888053e-08 61.930391547545 17.7383550733311 3.49132663606757 0.000627286691880218 -67.1018432572192 26.7258991295625 -2.51074221794826 0.013079959052298 CENPP other 0.000277363035858855 1 1 3.49132663606757 -2.51074221794826 0.362601182015893 231.973090439862 162.380413990073 1.42857802083227 0.155190798404111 34.7355174184425 671.537714355352 0.0517253412219552 0.958815908128947 PLSCR1 other 1 1 1 1.42857802083227 0.0517253412219552 2.75970424395577e-11 76.9337432637835 12.3135134213986 6.24791159362258 5.58396098817761e-09 -37.9734696697526 26.6002291901497 -1.42756174761887 0.15583433242515 C3orf62 other 3.33951810561088e-07 1 6.866596827162e-05 6.24791159362258 -1.42756174761887 0.000901586328519195 7.18198945771659 4.0072634834878 1.79224288278284 0.0750320882570546 -14.7516906673317 7.18445387053786 -2.053279335236 0.0417154777855576 ENO4 other 1 1 1 1.79224288278284 -2.053279335236 5.9628376444729e-21 106.236357251275 11.4642039632538 9.26678883172301 2.10653949237159e-16 -61.8943635627963 39.0130171841691 -1.58650542896006 0.11475895584247 ZNF559 other 8.46901830644485e-17 1 2.96706087500539e-12 9.26678883172301 -1.58650542896006 2.66921556958802e-08 856.335808443187 141.796418657426 6.03919207939983 1.12810076236503e-08 419.973385616553 297.096407476689 1.41359294507627 0.159512845093756 SBK1 other 0.000276957807500453 1 0.000137007837589233 6.03919207939983 1.41359294507627 1.01391258325166e-07 141.703583527652 25.2923461352746 5.6026270860662 1.15273592923237e-07 18.91514144925 54.2239801958342 0.348833512053827 0.727761811389985 SLC38A3 other 0.00100853884656042 1 0.00133567512120155 5.6026270860662 0.348833512053827 3.23750185322866e-17 97.2807467493738 16.7264949583398 5.81596724189188 3.47427773039432e-08 -99.8733548053601 28.779995383576 -3.4702352614815 0.000678088708471633 GTF2F2 essential 4.47617006227395e-13 1 0.000413195850475797 5.81596724189188 -3.4702352614815 0.00619708708314722 65.3482719645881 22.4361291778395 2.91263575131906 0.00413577379969183 -50.1642413952915 91.2266551070908 -0.549885790906219 0.583221027662279 FAM92A other 1 1 1 2.91263575131906 -0.549885790906219 2.28973291846679e-13 217.41912484114 32.5220800831084 6.68527733421531 3.93199903758017e-10 -98.2906945368483 77.5683558328871 -1.2671493869047 0.207002438270405 FOCAD other 2.96016671699387e-09 1 5.02273557060491e-06 6.68527733421531 -1.2671493869047 3.15392487045192e-12 102.979435510776 16.3007033084328 6.31748419453175 2.75433629062997e-09 -36.1077343221268 42.9663412884766 -0.840372562320327 0.402010878591328 PRR19 other 3.94398305050012e-08 1 3.4247417437693e-05 6.31748419453175 -0.840372562320327 0.00250363910725555 57.6718545800166 22.8785733070684 2.52078019927051 0.0127478965434883 -146.334244188349 83.7343400917333 -1.74760133092392 0.0825658766709593 ZP3 other 1 1 1 2.52078019927051 -1.74760133092392 0.761448108942203 -47.2675182838642 421.84926531966 -0.11204835985206 0.910928191006774 -572.642578114947 838.381361583068 -0.683033526692028 0.495592336680701 C10orf99 other 1 1 1 -0.11204835985206 -0.683033526692028 0.668704492419021 -1.5655956267752 4.80878825421246 -0.325569674523255 0.745212914710627 32.0550487174608 40.5885624403714 0.789755704320714 0.430942519844226 H3F3C other 1 1 1 -0.325569674523255 0.789755704320714 0.404028034485175 -2.80390458993235 5.57359283344233 -0.503069505384127 0.615717380447208 10.2971413034805 11.6926992741115 0.880647065496598 0.380039996422624 PDCD1 other 1 1 1 -0.503069505384127 0.880647065496598 0.162965615235553 -0.475582801618083 3.51608757853573 -0.135259088687472 0.89258716741657 -24.8995370949581 13.2738922812824 -1.87582787077978 0.0626092423987704 TCTEX1D4 other 1 1 1 -0.135259088687472 -1.87582787077978 3.20689499852564e-18 115.5848253882 13.6635126780357 8.45937850037674 1.82039898303338e-14 -51.5077194933044 37.3493959947348 -1.37907770986619 0.169844800355125 BLOC1S5 other 4.48099438143987e-14 1 2.52562154906051e-10 8.45937850037674 -1.37907770986619 0.455088919989199 -10.3316543353308 8.2579128722232 -1.25112174167918 0.212763101231859 -7.13555552158492 27.5668902018908 -0.25884513883599 0.796095954959642 CERKL other 1 1 1 -1.25112174167918 -0.25884513883599 1.52806124834283e-07 68.5607945960361 17.76157568966 3.8600626314899 0.00016843000173177 -55.9371083681451 26.4979537033838 -2.11099728659432 0.0364421199437147 SLC24A5 other 0.00149750002337597 1 1 3.8600626314899 -2.11099728659432 0.000273795565675668 143.534919966568 260.055194485443 0.551940215040014 0.581774115157887 -1080.60871915083 358.654653366595 -3.01295050547218 0.00301694212556083 IER5L other 1 1 1 0.551940215040014 -3.01295050547218 0.000347447233313095 583.113387131811 173.527030458342 3.36036054781561 0.00100341082434271 -560.192572269915 494.341357465023 -1.13321000521295 0.259062980879775 H2AFX essential 1 1 1 3.36036054781561 -1.13321000521295 0.0752374093696469 289.957773873002 520.942247297333 0.556602532002949 0.578601749300077 1986.46130231056 881.393956153227 2.25377232104053 0.0256126318060148 SERPINA5 other 1 1 1 0.556602532002949 2.25377232104053 3.48630610368343e-19 234.143568022394 24.9382394153882 9.38893737133323 6.73105857695147e-17 11.2077738717182 83.0930837931265 0.134882150957615 0.892877819322465 C19orf54 other 4.90279227361001e-15 1 9.51300508680551e-13 9.38893737133323 0.134882150957615 1.96168583259404e-07 21.1031470448481 3.92674955311087 5.37420244388382 2.75409457309497e-07 -0.276837603713582 6.60317152123297 -0.0419249451302894 0.966612142002337 LCTL other 0.00190656246069815 1 0.00311763505674351 5.37420244388382 -0.0419249451302894 0.145643556446615 -7.98887736732835 11.6939997222417 -0.683160386273457 0.495531989887525 -84.8808308429701 43.3008587427731 -1.96025744771486 0.0517703630646183 NCCRP1 other 1 1 1 -0.683160386273457 -1.96025744771486 0.718467477878018 0.687069084232273 3.54211647475938 0.193971341464413 0.8464573067608 4.31711728253385 5.73645028952899 0.752576430482469 0.45286840056212 C22orf34 other 1 1 1 0.193971341464413 0.752576430482469 0.591101320401394 20.8903661994986 21.3865816284718 0.976797814742279 0.330181567736684 13.3387311112025 32.2866595805399 0.413134442661333 0.680075424376229 COL25A1 other 1 1 1 0.976797814742279 0.413134442661333 6.37275988817468e-05 105.43536645554 27.9273712081684 3.77534160553934 0.000226683484077518 -85.0372624825203 78.3384236592445 -1.08551153457484 0.279369759623658 FAM83G other 0.478976633195209 1 1 3.77534160553934 -1.08551153457484 0.192643712939538 -38.6063443670152 34.4474506372908 -1.12073153899006 0.264102723880797 -87.4334954510259 47.9507315249979 -1.82340274424061 0.0701323020095578 CFAP77 other 1 1 1 -1.12073153899006 -1.82340274424061 1.7157493881541e-11 342.730618221399 66.7709907543818 5.13292695449345 8.5444746346356e-07 -207.242618856336 147.012657530869 -1.40969235123731 0.16066001645195 SRSF10 essential 2.09201322897629e-07 1 0.00937499756912218 5.13292695449345 -1.40969235123731 0.0878235582947287 -145.058580586313 144.665074291495 -1.00272011953642 0.317873100687137 346.890769503636 317.996766619102 1.09086256816926 0.277366716891427 HBA2 other 1 1 1 -1.00272011953642 1.09086256816926 0.000231272773931521 13.0761421319797 9.78343690073305 1.33655915243854 0.183489251723461 -62.919130977264 21.3819539534537 -2.94262774647407 0.00379828183147417 DUSP28 other 1 1 1 1.33655915243854 -2.94262774647407 0.0245135907779453 37.279995224641 67.1022108495223 0.555570297202903 0.579349179556605 -194.551859073846 96.4382505667779 -2.01737233857358 0.0454767263189038 C15orf52 other 1 1 1 0.555570297202903 -2.01737233857358 3.22148677825391e-12 633.855920348885 80.784565789843 7.84625026020229 6.3692625666293e-13 -118.817905044023 318.376830727928 -0.373198969197479 0.709506991883954 NBR1 other 4.02621417546173e-08 1 8.6768463945191e-09 7.84625026020229 -0.373198969197479 0.0116429597709371 99.2337465522988 57.5228556686555 1.72511857067576 0.0865253332195256 -316.804908111822 198.367211233127 -1.59706287214727 0.112315011344942 RALGAPA2 other 1 1 1 1.72511857067576 -1.59706287214727 4.40149281094412e-06 171.890402022344 36.7739856456237 4.67423911236556 7.72958431661094e-06 11.6127782761152 57.5340868883861 0.201841706441671 0.840379424643043 NDOR1 essential 0.0376415665191941 1 0.0792359688295787 4.67423911236556 0.201841706441671 0.0614632523472413 27.616500316618 14.2873214853298 1.93293755900815 0.0551028847172182 2.07291660384573 27.7841731435194 0.0746078205436618 0.940624849829537 NKAIN2 other 1 1 1 1.93293755900815 0.0746078205436618 0.00525284087008328 9.75241855873643 11.4358543337094 0.85279317785548 0.395107028205087 -50.5358569367454 22.7843137012482 -2.21801093503979 0.0280274259432556 CFAP54 other 1 1 1 0.85279317785548 -2.21801093503979 0.000269463630005847 35.777927836676 69.2852729462994 0.516385752920482 0.60633545147257 -492.746332935678 144.921574212284 -3.40008956992072 0.000860626240602593 CLN3 other 1 1 1 0.516385752920482 -3.40008956992072 0.470797334215139 2.44737671643628 5.52592591076547 0.442889889578209 0.65846285856026 -10.1607606907262 11.6351692758937 -0.873280005627232 0.383861382418411 ASAH2 other 1 1 1 0.442889889578209 -0.873280005627232 1.38842165340916e-09 1289.65622918055 189.010191261634 6.82321001091082 1.8550726645997e-10 -150.078281145907 823.30179272758 -0.182288296310762 0.855593149122509 SUMO2 other 1.55544877831429e-05 1 2.39786692626158e-06 6.82321001091082 -0.182288296310762 0.000258242659580803 77.2595439957849 20.7206215556277 3.72863061990537 0.000270020064030892 6.944666379269 37.222676493115 0.186570849641979 0.852242674209219 NANOS1 other 1 1 1 3.72863061990537 0.186570849641979 7.44986099293832e-07 490.187365455237 91.9779311882717 5.32940194590659 3.41911295611456e-07 264.477064074966 143.630164856968 1.8413754822209 0.067478029366478 RTL6 other 0.00686430191889337 1 0.0038468439869245 5.32940194590659 1.8413754822209 0.0186080106422758 -72.4827419850005 27.21842918053 -2.66300239092597 0.00856786930052544 -149.408764966449 86.9041985765054 -1.71923528913184 0.0875807886119288 DPYD other 1 1 1 -2.66300239092597 -1.71923528913184 6.56468358696932e-08 230.297088754822 39.6743408557069 5.80468594531659 3.56332338639977e-08 11.6426049380939 73.3336892975991 0.158762023970271 0.874064378595579 PTAR1 other 0.000662901748612162 1 0.000423500984473612 5.80468594531659 0.158762023970271 0.1347102195006 -17.6529275691496 21.6812716928518 -0.814201667652626 0.416811582956252 -76.4180170120655 37.9382338549406 -2.01427449955248 0.0457562932422296 SAXO2 other 1 1 1 -0.814201667652626 -2.01427449955248 0.00277973756761589 3.67667194542575 1.88315867057661 1.95239626000287 0.052728577391655 -6.24493712862577 3.56750178298152 -1.750507079889 0.0820484691400345 LINC00319 other 1 1 1 1.95239626000287 -1.750507079889 7.09298040122673e-06 13.1780749446543 6.84833497912043 1.92427429219399 0.0561763293572742 -39.1491828363068 15.0769243094021 -2.59662926157247 0.0103322648012711 RHCE other 0.0594138649805857 1 1 1.92427429219399 -2.59662926157247 0.00595396070905544 15.4398980625553 56.2224037038953 0.274621806350936 0.783972498703406 -216.164730277321 87.7953331665625 -2.46214374364546 0.0149062286075157 PARVB other 1 1 1 0.274621806350936 -2.46214374364546 0.00227148607793123 182.093479091488 68.0280192235159 2.67674233602471 0.00823423894568805 -111.634145616642 126.055433524409 -0.885595666092612 0.377207280378833 UROS other 1 1 1 2.67674233602471 -0.885595666092612 0.035044163204357 8.01718063457996 3.49085390673969 2.29662450757433 0.0230150954589795 -4.61761192216575 10.7620696864092 -0.429063559028712 0.668488495597099 CYP51A1-AS1 other 1 1 1 2.29662450757433 -0.429063559028712 0.0297340242909702 47.9263521581179 19.2763412539412 2.48627846574978 0.0140845800845403 -14.4261523858354 59.5907887788712 -0.242086951380485 0.809067049727056 ZBED6CL other 1 1 1 2.48627846574978 -0.242086951380485 3.03341028723612e-15 96.9704417137169 64.623883292971 1.50053566533759 0.135536499166024 -480.319897218968 88.8926183047764 -5.40337214021696 2.45731823750548e-07 SMIM15 other 4.0826669055911e-11 0.00358989621317176 1 1.50053566533759 -5.40337214021696 0.389336986780934 -7.7706919945726 13.4413667973969 -0.57811769529848 0.5640345877972 -44.4798037783113 32.3636664354187 -1.37437468239484 0.171335180043769 VWC2 other 1 1 1 -0.57811769529848 -1.37437468239484 6.22389064941508e-09 63.8718709812484 15.4287159331688 4.1398047159541 5.70695839453099e-05 -69.6762045039927 36.3238473928643 -1.91819450595094 0.0569367840328086 FAM221A other 6.71806756697864e-05 1 0.536111671582241 4.1398047159541 -1.91819450595094 0.634499827259888 64.0504996012572 150.368654795765 0.425956458068021 0.670734310492739 -173.228065237448 334.119830227799 -0.518460892067803 0.604880876943282 TMEM120B other 1 1 1 0.425956458068021 -0.518460892067803 2.33269890187656e-05 18.7661000718219 4.13180682746187 4.5418628835922 1.10076215552068e-05 1.06094599678511 13.8247905748433 0.0767422834394104 0.938925657896075 FSIP2 other 0.185496216677224 1 0.111353099652472 4.5418628835922 0.0767422834394104 2.47569892795341e-09 109.587940280082 19.6247142439976 5.58418017799164 1.01010112120399e-07 -98.758842572946 64.0194469801403 -1.5426381706106 0.124931800472686 RBM34 other 2.7366375949597e-05 1 0.00117369813153247 5.58418017799164 -1.5426381706106 0.111367898600746 96.0396949550256 63.7624401248103 1.50621109805451 0.134640875520947 -58.318872562713 99.3556805264777 -0.5869706921002 0.558326095732123 NOXA1 other 1 1 1 1.50621109805451 -0.5869706921002 0.000772933719968172 95.1201865222623 24.9404287710076 3.81389539833559 0.000200796077016193 53.486263537906 61.4664950257462 0.870169407178699 0.385626551444583 TMEM198 other 1 1 1 3.81389539833559 0.870169407178699 0.137319735043519 -23.1023797071129 17.0900664330654 -1.3518016326967 0.178433835225302 -100.100398294174 54.2495488175486 -1.84518397804249 0.0669439374568213 BCL2L15 other 1 1 1 -1.3518016326967 -1.84518397804249 0.00800909764691618 15.1745586612725 4.80409705263273 3.15867029642055 0.00192407524988964 11.4709577384734 19.1317609834113 0.599576680286752 0.549711421060114 FZD9 other 1 1 1 3.15867029642055 0.599576680286752 0.00453648468137543 12.0817089429335 3.80805679395052 3.17267036618954 0.00182578468278929 5.62658045851812 14.4420858319419 0.389596109868955 0.697376993962347 SPRED3 other 1 1 1 3.17267036618954 0.389596109868955 0.034757626591927 557.002365306805 233.012977124892 2.39043495422257 0.0180776707922009 -371.38970521128 810.865204113153 -0.458016577018459 0.647607785048324 PRELP other 1 1 1 2.39043495422257 -0.458016577018459 3.88521152632028e-06 50.2764632441218 14.8091818697575 3.39495211054121 0.00087183232004731 -41.2205921539157 29.8184474663176 -1.38238559202245 0.168841999820418 ZNF548 other 0.033443900818565 1 1 3.39495211054121 -1.38238559202245 2.30539961832369e-13 157.165137962401 21.9017244851632 7.17592525962369 2.8988737942478e-11 -165.566176470588 91.157734958193 -1.81626031566625 0.0712879543549703 MTF1 other 2.98019008660703e-09 1 3.82970216958077e-07 7.17592525962369 -1.81626031566625 8.21390528722141e-18 451.158873343153 54.3923977103205 8.29452078479617 5.24835929405432e-14 17.6252454590081 116.758107434773 0.150955217125752 0.880209885595792 TMEM201 other 1.1425542254525e-13 1 7.23538812278329e-10 8.29452078479617 0.150955217125752 3.05182160777166e-07 94.3976089528694 22.965053603173 4.11048938025674 6.40019136358378e-05 -45.1462679944784 39.2438605907559 -1.15040333226321 0.251761004938462 NHLRC3 other 0.00290869117436717 1 0.598225886754176 4.11048938025674 -1.15040333226321 0.231431582512912 -55.3160065475957 45.3987457316943 -1.21844790326394 0.224992525880582 -180.571176056878 108.553245599137 -1.66343415215504 0.0983416791828717 SNTN other 1 1 1 -1.21844790326394 -1.66343415215504 0.865801613851056 -1.39440408523055 12.7247759417763 -0.109581818305548 0.912925610066125 -23.9852123164838 45.0355391587406 -0.532584105009626 0.595314594920002 ZDHHC11 other 1 1 1 -0.109581818305548 -0.532584105009626 0.000155143667419928 33.6714605782567 7.86680852354132 4.28019322924859 3.25883752803176e-05 31.4070628400727 33.3719753901104 0.941120879808033 0.348107340765596 LINC00910 other 1 1 0.314445233079785 4.28019322924859 0.941120879808033 8.83067471401305e-08 81.2106895183025 14.6364234948158 5.54853373483402 1.22800886776576e-07 31.8062412144091 30.0705398132705 1.05772099243701 0.291838987258359 SLX4 other 0.000882714244412745 1 0.00142043785734465 5.54853373483402 1.05772099243701 0.151752855437649 -1.59444661712939 10.813607521365 -0.147448167873595 0.883025742148538 -30.0959830158109 16.849940688098 -1.78611803880528 0.0766055737042395 ENTPD8 other 1 1 1 -0.147448167873595 -1.78611803880528 3.78849620502273e-05 1665.03777836646 797.34962367491 2.08821541884281 0.0383926948234064 -4997.67141662853 1746.93533731593 -2.86082221240494 0.00480114968921375 RPL14 essential 0.292699216800056 1 1 2.08821541884281 -2.86082221240494 9.03494190937452e-11 12.6395243910977 2.53610162342864 4.98383987231944 1.68859907333005e-06 -31.1908736610372 11.1940529125991 -2.78637897324314 0.00601442238585518 ZNF563 other 1.07199585754729e-06 1 0.0181895892179113 4.98383987231944 -2.78637897324314 0.00236947702464267 74.4340090806934 21.5606477502124 3.45230857361232 0.000715494363556453 75.4630763934449 100.26934385205 0.752603672213042 0.452822267518154 FBF1 other 1 1 1 3.45230857361232 0.752603672213042 0.0644542233186925 42.3081155712574 18.1529744705746 2.33064369918205 0.0210609371534403 10.1626109114536 65.2843546646128 0.155666866336693 0.876498160727667 KLRG2 other 1 1 1 2.33064369918205 0.155666866336693 3.82943347660079e-05 20.2014243568188 5.28815156885292 3.82012960366051 0.000197221761383557 68.3703073946008 18.8214141381295 3.63258078765147 0.000388612922992683 ASTL other 0.295440792719751 1 1 3.82012960366051 3.63258078765147 2.39459136642497e-14 521.403224423291 59.497655015366 8.76342478184446 3.6325851822453e-15 103.174148872308 314.508946649595 0.328048375003008 0.743329517269283 MSL1 other 3.17163626482988e-10 1 5.07181543145088e-11 8.76342478184446 0.328048375003008 0.442107846969084 3.38576779026217 8.08449880477533 0.418797487886605 0.676001396337219 36.2984662029606 28.3552628625918 1.28013153603481 0.202600944897611 LRRK2 other 1 1 1 0.418797487886605 1.28013153603481 0.0126481287522849 -55.1594672956902 31.9799580424361 -1.72481362303527 0.0865804587023043 -291.996912959761 99.2230777419305 -2.94283265148473 0.00375906822544921 GJB3 other 1 1 1 -1.72481362303527 -2.94283265148473 0.00582346374789126 51.8474599836454 24.6925387186117 2.09972172462631 0.0373731732477808 -69.7694407082344 58.8941305367928 -1.1846586420806 0.237965734049878 HACD4 other 1 1 1 2.09972172462631 -1.1846586420806 0.145881350594891 31.824736498461 16.2691003263841 1.95614605970865 0.0522690919954543 31.7300314025431 57.8691286224631 0.548306707874402 0.584280464518502 USP32P1 other 1 1 1 1.95614605970865 0.548306707874402 4.66238650758375e-13 426.115671641792 71.2757327303734 5.97841166016111 1.51116413544461e-08 -176.96338619403 107.938543892035 -1.63948280024082 0.103153964264787 FAM120AOS other 5.97997693462692e-09 1 0.000182457957713582 5.97841166016111 -1.63948280024082 1.43691051055467e-07 9.0711249351996 1.59779326324013 5.67728325303142 6.80635872951118e-08 -1.51829963711768 5.90746579100699 -0.257013699415578 0.797518074186655 UTS2B other 0.00141162088556891 1 0.000797841370273301 5.67728325303142 -0.257013699415578 0.00530692212471229 -1.75400825140301 33.1959753127297 -0.0528379791489482 0.957927746983914 -156.759513457645 52.9090933208721 -2.96280853854294 0.00352001959215523 C9orf152 other 1 1 1 -0.0528379791489482 -2.96280853854294 1.44975745619811e-11 796.636299199467 117.844560824075 6.76005997755577 4.92772186459781e-10 51.7350525350232 262.417787194487 0.197147659417921 0.844037396452823 NOC2L essential 1.77218351445657e-07 1 6.28185983298929e-06 6.76005997755577 0.197147659417921 2.56004113398899e-12 16.7293246667703 2.39868033109397 6.97438689512268 8.98817405643472e-11 4.10608916008745 4.53665195039893 0.90509239081618 0.366858290703933 MSANTD1 other 3.21054758613559e-08 1 1.17286683262417e-06 6.97438689512268 0.90509239081618 7.53958801994741e-07 496.957582429531 107.004635380959 4.64426219163552 8.74471904311766e-06 -92.216396205387 167.412204072604 -0.550834371461918 0.582762828856363 NELFB essential 0.00694320660756957 1 0.0892923261492744 4.64426219163552 -0.550834371461918 1.01538904734017e-10 261.110088197776 41.0246948995588 6.36470518152676 2.220415877607e-09 62.9742041168082 81.5115842152547 0.772579808417253 0.440978682442639 ZNF292 other 1.20222063205076e-06 1 2.77107901525353e-05 6.36470518152676 0.772579808417253 0.0553293541395444 48.5804854893121 19.9999899350612 2.42902549686525 0.0163378548187776 37.8855378683837 74.0242740391709 0.51179884382704 0.609554607142363 KCTD21 other 1 1 1 2.42902549686525 0.51179884382704 1.98025719315501e-07 44.1663732922985 11.7884271192226 3.74658746630237 0.000253458798347571 -37.8124812340489 23.8767300373919 -1.58365409228287 0.11533730711271 ADAT2 other 0.0019238198631501 1 1 3.74658746630237 -1.58365409228287 1.04438322770779e-12 38.1518765490094 6.34443025058737 6.01344408278068 1.35850176009276e-08 -73.6495003843199 26.78202506656 -2.74996010201927 0.0067038688474183 ZNF567 other 1.32532231596118e-08 1 0.000164378712971224 6.01344408278068 -2.74996010201927 0.000338996842642766 -533.33625162127 511.067903034974 -1.04357219158952 0.29832942486846 -3564.76707738867 970.64212353702 -3.67258641567982 0.000331354117291229 NDUFA4 other 1 1 1 -1.04357219158952 -3.67258641567982 9.70664792822857e-08 53.8263263263263 25.4388965302012 2.11590649234425 0.0359507328983103 -184.861444778112 50.972828380426 -3.62666641526017 0.000389069240041462 ALKBH2 other 0.000966782133651566 1 1 2.11590649234425 -3.62666641526017 2.35051056514728e-05 66.5151806080415 14.0330431430682 4.73989710784131 4.78193452285675e-06 36.5249106322138 56.1379806505721 0.650627439906705 0.51624412846139 RNFT1 other 0.186771569506603 1 0.0499377422221931 4.73989710784131 0.650627439906705 0.474592126341928 34.117313642391 44.7311269077085 0.762719743519619 0.44679726425183 -95.1376545938309 139.953507821659 -0.679780421903136 0.497664059426766 RELN other 1 1 1 0.762719743519619 -0.679780421903136 0.231765460471148 25.0939643347051 26.4888227819205 0.947341621834267 0.344978316780723 -109.696816415181 99.7027505684641 -1.10023861718693 0.272979078531515 FAM111B other 1 1 1 0.947341621834267 -1.10023861718693 0.749443349903312 -13.1790866214017 20.358265335561 -0.647358033907781 0.518364079666128 -46.8200147471696 87.36456555871 -0.535915384546907 0.592790217231101 APOD other 1 1 1 -0.647358033907781 -0.535915384546907 0.000144282987210902 1741.07938853739 403.090065702124 4.31933093043285 2.80290357028234e-05 1469.87785526255 814.047176602215 1.80564210221542 0.0729401525693014 H1F0 other 1 1 0.27230208185293 4.31933093043285 1.80564210221542 0.0635808591304001 407.885276488385 186.17919562376 2.19082091917864 0.029958049694765 159.372831583995 411.089840732699 0.387683702666892 0.698781982440117 LITAF other 1 1 1 2.19082091917864 0.387683702666892 0.000652800868995124 106.14133810825 35.5667215836704 2.9842879349606 0.00331624235531228 -221.740918322895 130.172276088341 -1.70344196925935 0.0905426034724834 TMEM120A other 1 1 1 2.9842879349606 -1.70344196925935 1.22239996996943e-20 497.366409611861 46.1611117231192 10.7745760672996 3.72772541681145e-20 35.7333304929484 150.610722559168 0.237256218453572 0.812799978907508 ARID2 other 1.73299643742567e-16 1 5.33996665958241e-16 10.7745760672996 0.237256218453572 4.40937576804686e-10 1520.74951919379 313.102972138511 4.85702677559073 2.93485004788002e-06 -166.557350565427 500.786824407153 -0.332591319195753 0.739901043356835 SF3B3 essential 5.06769557021625e-06 1 0.0311094105075282 4.85702677559073 -0.332591319195753 2.29089195352943e-11 30.7938224948429 10.6751889074571 2.88461616574596 0.00446989817700846 -183.941125474349 34.2422173655161 -5.37176443659834 2.76554443252759e-07 BLOC1S3 other 2.78114283158473e-07 0.0040399073070363 1 2.88461616574596 -5.37176443659834 0.671831301320746 15.4042003556212 17.2703634228006 0.89194419240097 0.373814380758082 6.81261113161285 71.2793023320222 0.0955762880489402 0.923981354376416 SP6 other 1 1 1 0.89194419240097 0.0955762880489402 0.479784862464301 -4.79647089212489 8.06416226784388 -0.594788489221128 0.552852140771825 3.89117238707176 11.3363607852236 0.343247049100953 0.731877721801248 ANKRD34B other 1 1 1 -0.594788489221128 0.343247049100953 0.767842201019248 2.10027051397655 3.08924838608974 0.679864566227062 0.497604344469034 4.04345055605649 7.47572578019355 0.540877324148158 0.589368594226832 PLAC9 other 1 1 1 0.679864566227062 0.540877324148158 0.01294421311396 0.477590444734603 2.51854587438515 0.189629440381425 0.849980090831008 -11.338716491282 4.18167138779096 -2.71152738696473 0.00787252564533605 UBE2Q2P1 other 1 1 1 0.189629440381425 -2.71152738696473 0.00853643858972177 1332.10165593376 507.405382540227 2.62532030950253 0.00957860161899863 -2462.98891862508 2028.86930768891 -1.21397120518851 0.226718783966894 CLDN4 other 1 1 1 2.62532030950253 -1.21397120518851 1.04191284580269e-09 10.0800229061807 1.65379196222256 6.09509728940391 8.83062673946516e-09 -2.68594759684185 6.39701353581047 -0.419875240501825 0.675177384929585 ZNF573 other 1.17538188135001e-05 1 0.000107742476848214 6.09509728940391 -0.419875240501825 5.3280246230026e-08 27.3298315378331 5.98625204500597 4.56543281712185 1.02236264876202e-05 -54.6312998206318 23.2926713089654 -2.34542870141322 0.0202973647804187 FAM47E other 0.000541007620219684 1 0.103739137969883 4.56543281712185 -2.34542870141322 4.38119068210296e-06 557.347285717568 121.885333771761 4.57271821367156 9.74825369569981e-06 -1256.42983987686 530.915360339405 -2.36653510848443 0.0191831095955182 JPT1 other 0.0374854674760729 1 0.09911049532418 4.57271821367156 -2.36653510848443 2.62433326757937e-23 35.9641738368977 3.28550683969452 10.9463092276629 8.43347509475659e-21 -8.39696980625667 12.9316518694679 -0.649334662811501 0.51712852763064 ZNF527 other 3.76145687242151e-19 1 1.21028801084852e-16 10.9463092276629 -0.649334662811501 1.00021561565864e-08 399.674314345991 64.5690564838279 6.18987385151112 6.09691020100121e-09 89.9415260196901 292.501969960554 0.307490325729496 0.75892070437739 ZNF33A other 0.000106632986785367 1 7.49127356397019e-05 6.18987385151112 0.307490325729496 0.577960391708404 -8.77477477477484 61.7072281628154 -0.142200112304874 0.88710661187225 -84.9099099099098 96.0127313613455 -0.884360945741143 0.377871138322383 PCDH18 other 1 1 1 -0.142200112304874 -0.884360945741143 6.58596170533736e-11 46.9675118024559 10.7377611800577 4.37405069966398 2.23700464802276e-05 -93.1853819198663 30.1012378089325 -3.09573255795526 0.00233294095372304 ZNF600 other 7.85639371829693e-07 1 0.219427785924552 4.37405069966398 -3.09573255795526 5.66492139719638e-19 687.94216870588 68.0176037803256 10.1141782490266 1.0427469601065e-18 -163.144408714163 284.369385787203 -0.573705950317189 0.567014706939683 PAX8-AS1 other 7.95524911808288e-15 1 1.48622724223979e-14 10.1141782490266 -0.573705950317189 1.2862105383218e-06 93.252869680112 20.5591268842278 4.53583803462257 1.14735933860561e-05 -35.865798818345 34.589228097116 -1.0369065975582 0.301404787299004 C15orf61 other 0.0116170535821225 1 0.115825925232237 4.53583803462257 -1.0369065975582 0.565080990030249 -1.53962519255704 3.44792063287463 -0.446537306536959 0.655836451659913 2.09524231711237 6.36230129797474 0.329321454452233 0.742360195072931 NUGGC other 1 1 1 -0.446537306536959 0.329321454452233 4.36400609920731e-10 311.061437849844 97.2007008903992 3.20019747800571 0.0016640071253069 -594.453341110749 201.885449075973 -2.94450810512375 0.00372980666283077 TSPYL1 other 5.01686141164872e-06 1 1 3.20019747800571 -2.94450810512375 7.14785204841108e-15 441.267462729583 87.6674398530507 5.03342476373487 1.34575294534698e-06 -564.467399848037 193.022985886818 -2.92435326940296 0.00398040936691764 PNRC2 other 9.56025211474982e-11 1 0.0145866161746159 5.03342476373487 -2.92435326940296 0.0460960699068183 -14.5656789031402 7.02826067511427 -2.07244431822435 0.0399017525420929 -46.4366330264162 21.8063342807404 -2.1295020258141 0.034812871641246 GJB5 other 1 1 1 -2.07244431822435 -2.1295020258141 1.07866399570231e-06 84.5222389282675 18.7571854202284 4.50612589440607 1.32040633820444e-05 -19.6867099432788 44.3624789335775 -0.443769383869533 0.657848799624431 FHIT other 0.00981710309007418 1 0.132489571975433 4.50612589440607 -0.443769383869533 0.682207318681058 8.00088781275226 18.3155876135149 0.436834896132323 0.662885425333124 -29.1030831315577 52.7401038128583 -0.551820740338821 0.581926530615799 ALKAL2 other 1 1 1 0.436834896132323 -0.551820740338821 2.68516387160954e-19 56.3103737739684 6.36456042465384 8.84748828149133 2.04846085352278e-15 -29.7915944472011 18.1223575816456 -1.64391384029273 0.102247291061832 ZKSCAN3 other 3.77856260012895e-15 1 2.86559188799302e-11 8.84748828149133 -1.64391384029273 3.08972924074517e-06 271.53502613026 100.47511227961 2.70251030299533 0.0076492105245593 -294.138627907987 149.257340469374 -1.97068115365717 0.0505415273652529 RRP7A essential 0.0268497471020755 1 1 2.70251030299533 -1.97068115365717 9.60707919274521e-09 94.8787314354458 21.4253582492146 4.42833815574235 1.80522554594253e-05 -34.3851169737632 32.8117406768988 -1.04795162537573 0.29632437235752 LIN54 essential 0.000102507534986591 1 0.178771485814688 4.42833815574235 -1.04795162537573 1.65955592636046e-05 307.18461793303 64.7859099999318 4.74153435420377 4.79396895957685e-06 135.321283241101 120.123562932476 1.126517395402 0.261698926141184 FAM53B other 0.133892972138762 1 0.0500586238759015 4.74153435420377 1.126517395402 0.590602684447518 1.80530167779925 3.55936698626515 0.507197399078413 0.612727999673738 12.3295098320909 12.4832347643925 0.987685488961558 0.32482641778865 FAM180A other 1 1 1 0.507197399078413 0.987685488961558 4.00270180574408e-06 193.186563525085 104.768987944284 1.84392888884086 0.0671027805956095 -793.754654578045 262.770898905892 -3.02070989551365 0.00295056871919151 KAZN other 0.0344272382312048 1 1 1.84392888884086 -3.02070989551365 1.84741143066579e-17 933.879665471923 117.725209053689 7.93270764162352 7.03212879182956e-13 -280.501314217443 268.802595143741 -1.04352160018189 0.298558124888177 SLC35E2B other 2.56143594861811e-13 1 9.5721337114384e-09 7.93270764162352 -1.04352160018189 0.62796058729201 -5.51507143157571 8.82497358261204 -0.624939143437451 0.532948025787456 -45.3146985012687 55.5845307322392 -0.815239382330271 0.416210868020476 TOGARAM2 other 1 1 1 -0.624939143437451 -0.815239382330271 0.00245277594422203 42.0664803568548 12.9073753261537 3.25910413960128 0.00137909784679588 -12.8897726662008 45.2338131693918 -0.28495878996385 0.776063605291513 NEMP2 other 1 1 1 3.25910413960128 -0.28495878996385 0.013444379571862 20.6830207516223 8.13572098317906 2.54224804345987 0.0120081587754546 -37.1310978118365 33.4636708871088 -1.10959428023004 0.268914851921181 ALG1L other 1 1 1 2.54224804345987 -1.10959428023004 0.54342750731775 -2.3463983641204 2.14306233513009 -1.09488106139384 0.275312088302931 -3.42952985608889 4.16387411186036 -0.823639179273032 0.411443582099753 KIAA0408 other 1 1 1 -1.09488106139384 -0.823639179273032 3.88270848648691e-10 121.346444451692 17.3825925204207 6.98091750750854 8.84220718821007e-11 65.7058152049834 96.8700830735351 0.678288003068041 0.498634150129815 C8orf76 other 4.478315968314e-06 1 1.15435014842082e-06 6.98091750750854 0.678288003068041 0.0203467015631029 -603.822140540895 297.844918644395 -2.02730381733258 0.0443338972172841 -2162.2526457702 788.580688049952 -2.74195485450848 0.00682156911539994 CXCL17 other 1 1 1 -2.02730381733258 -2.74195485450848 5.39189137990495e-08 1281.488749172 269.613830202865 4.75305272065522 4.51797009454364e-06 -345.313479061298 446.177076844153 -0.77393818952719 0.440138637931337 HMGB1 essential 0.000547223056146553 1 0.0472715210992101 4.75305272065522 -0.77393818952719 6.23912397300582e-08 119.373931623932 21.6613867241486 5.51090902646831 1.74800152635556e-07 37.54695998446 49.5475300959339 0.757796804639133 0.449893400924939 MMP23B other 0.000630713042431158 1 0.00200338454935611 5.51090902646831 0.757796804639133 1.99014551383131e-05 292.357755622537 66.6122968003676 4.38894573022625 2.11295212704219e-05 107.93811621565 106.483561581111 1.01365989841944 0.31234538117546 RASSF10 other 0.159211641106505 1 0.207956748343492 4.38894573022625 1.01365989841944 4.3396434106099e-07 43.0798074235129 25.9574375282293 1.65963251868227 0.0989973545285738 -166.864537971735 47.7885158467644 -3.4917288184214 0.000624377817400865 BLOC1S2 other 0.00408837805713559 1 1 1.65963251868227 -3.4917288184214 0.0577683104468285 23.5326347305389 12.6407315910363 1.86165132619589 0.0647049123471884 -42.4290024601958 48.0750210699343 -0.882558166713537 0.378956225259727 SYCP2 other 1 1 1 1.86165132619589 -0.882558166713537 0.0226606663606997 251.919105788698 90.415845257763 2.78622740373119 0.0060170955978717 203.152615979824 335.421091635229 0.605664405268684 0.545646904952651 IL1RAP other 1 1 1 2.78622740373119 0.605664405268684 0.0496308447534178 129.001423630353 57.6063587722502 2.23936083411151 0.026583940750558 -57.1792532151115 250.026811880485 -0.228692486158019 0.819415330449493 PTPRT other 1 1 1 2.23936083411151 -0.228692486158019 0.000127989428298639 150.318746183595 41.8761088839623 3.58960634571192 0.00044225021738946 24.6023400926113 62.8300647833806 0.39156954839109 0.695907240576135 SPOCK3 other 0.925235577170864 1 1 3.58960634571192 0.39156954839109 0.00304797258714886 23.4636085465228 8.33782632946817 2.81411576823037 0.0055215428838424 -11.8458955939014 25.2532808699752 -0.469083429392555 0.639664905905616 ZNF676 other 1 1 1 2.81411576823037 -0.469083429392555 2.14101098495083e-09 7.12203906647995 1.42479096696902 4.99865540390866 1.61045042199869e-06 -9.16417568841319 5.12979480066317 -1.7864604812708 0.0760719236108937 ZNF699 other 2.37587988999994e-05 1 0.0173735391525219 4.99865540390866 -1.7864604812708 2.03612380606482e-08 132.03167115903 40.2965035629456 3.27650439827336 0.00129367894906389 -170.829093665768 60.2696035553324 -2.83441541985478 0.00519492132956067 TDRD7 other 0.000213039633828562 1 1 3.27650439827336 -2.83441541985478 0.00211424221241939 31.3266948631704 21.9567216672425 1.42674736866147 0.155663961866263 -108.006131901532 46.8348304302616 -2.30610703421584 0.0224297420171755 CCDC189 other 1 1 1 1.42674736866147 -2.30610703421584 2.34584399320388e-05 138.569032389765 46.2771046028523 2.99433237189225 0.00326457664397907 -44.5335805661417 73.342746327158 -0.60719815927661 0.544724462861902 KIAA0895L other 0.186447680579845 1 1 2.99433237189225 -0.60719815927661 0.00530042564129376 -2350.9092127146 976.453522587999 -2.40759970478035 0.0172102379397482 -8887.06648631178 2876.2330403374 -3.08982838374921 0.00236710611918725 HLA-DRB1 other 1 1 1 -2.40759970478035 -3.08982838374921 0.00172376125485807 19.7940840081905 6.54814802768581 3.02285225143054 0.00308247467137766 -11.8666273128078 22.499178624158 -0.527424912306188 0.598905872851622 MYT1 other 1 1 1 3.02285225143054 -0.527424912306188 0.153796731771924 307.139960009696 416.03864511034 0.738248630552669 0.461479673651191 1369.04621101955 703.905181867763 1.94492986596133 0.0535933971976437 SERPINA3 other 1 1 1 0.738248630552669 1.94492986596133 0.0828651325963415 60.2768721706828 30.3231384967349 1.98781772464526 0.0485818344069343 -37.829104159477 136.559213114424 -0.27701612580163 0.782134444684523 AKR1C3 other 1 1 1 1.98781772464526 -0.27701612580163 0.183740944909846 70.9047697476775 177.736935707298 0.398930978895943 0.690500298668714 -816.545754002241 526.810832002921 -1.54997905205889 0.123212576530816 SPATS2L other 1 1 1 0.398930978895943 -1.54997905205889 0.000574898146925993 110.28227165487 31.3436922161775 3.51848374767891 0.000654679504117081 -87.0294068082236 115.515082674105 -0.753402973824239 0.452977967291877 ZNF250 other 1 1 1 3.51848374767891 -0.753402973824239 5.90404024862646e-11 83.3482401864614 12.3122907371071 6.76951527267501 2.43365275516161e-10 -44.0719352080083 39.7542864509987 -1.10860838270438 0.269294519260771 WDSUB1 other 7.05355688503403e-07 1 3.13259782644402e-06 6.76951527267501 -1.10860838270438 1.37315935348302e-11 41.1229628836736 6.32101855360408 6.5057494349904 9.97199942300328e-10 0.555772610095711 8.75615466968731 0.0634722239454866 0.949471733313347 ZNF79 other 1.67951120524508e-07 1 1.25856604717724e-05 6.5057494349904 0.0634722239454866 1.43013676261436e-06 369.81038557634 91.4132509666402 4.04547898325262 8.65046628270966e-05 35.4886668017197 144.160962334566 0.246173903302326 0.805913396851674 PLEKHG4 other 0.0128669404532414 1 0.796448430649078 4.04547898325262 0.246173903302326 0.330052339233832 31.6387808956655 21.1719547019797 1.49437221744609 0.137137919020024 30.1621921017166 31.5885063635275 0.954847049575672 0.341161244419444 FAT4 other 1 1 1 1.49437221744609 0.954847049575672 0.0554884472950686 59.8854989324209 25.0124124155058 2.39423122958329 0.017842226249956 43.3780901911351 102.957933685814 0.421318577774761 0.674102400931077 KIF19 other 1 1 1 2.39423122958329 0.421318577774761 0.134015219080018 16.4583203893548 13.8118849488643 1.19160566789315 0.235349326904332 -27.4133443788618 35.2751557819086 -0.777128938801771 0.438340035288208 ZNF681 other 1 1 1 1.19160566789315 -0.777128938801771 0.000272296749230093 77.2357390207544 24.9949551791028 3.09005311141058 0.0023727978480733 -47.1549730535489 45.4461669286615 -1.03760066558682 0.301071974650795 ACADSB other 1 1 1 3.09005311141058 -1.03760066558682 5.6399561498871e-07 445.354643526849 95.3607466464952 4.67020927570744 6.72943247531366e-06 -415.705153316479 338.346063851885 -1.22863895203598 0.221170533619511 STK40 other 0.00525643913169477 1 0.0693468016581073 4.67020927570744 -1.22863895203598 0.00269900023314094 187.541123098452 76.2899428179567 2.45826797309264 0.0150406362190407 -373.862343700627 245.108473319021 -1.52529342881601 0.129185132248502 TMEM63A other 1 1 1 2.45826797309264 -1.52529342881601 0.59236846015846 -12.4469926925239 12.5984117916482 -0.987981096218437 0.324721758980946 0.908356754731179 45.3164816055181 0.020044732568571 0.984033804985918 CTSE other 1 1 1 -0.987981096218437 0.020044732568571 0.000213200593958994 118.653040567626 28.4692129821695 4.16776679572912 5.19487391062918e-05 90.2100537160265 70.5706680354618 1.2782938893351 0.203133495516886 HRCT1 other 1 1 0.490655840858926 4.16776679572912 1.2782938893351 1.18848110492942e-10 195.13449289564 50.3021753545198 3.87924560956599 0.000158039216739899 -245.307246893234 82.8895330484565 -2.95944780808247 0.00359714417909526 MPHOSPH8 other 1.40276424814819e-06 1 1 3.87924560956599 -2.95944780808247 6.433790846978e-14 51.879063201332 9.89294524057108 5.24404633198366 5.21859640989358e-07 -30.5656989792224 19.552982637933 -1.56322437068628 0.120093188719301 RNF216P1 other 8.43984683306574e-10 1 0.00580829780421156 5.24404633198366 -1.56322437068628 0.00457765307447628 442.318273708644 165.515337025128 2.67237031720809 0.00834276622754363 -479.834992154554 515.736093650251 -0.930388619416573 0.353626068907288 GREB1 other 1 1 1 2.67237031720809 -0.930388619416573 0.556018662723888 0.0339578454332465 4.46455742271671 0.00760609444968969 0.99394118162053 -15.672131147541 15.593088795964 -1.00506906313504 0.316450491216833 SIRPB2 other 1 1 1 0.00760609444968969 -1.00506906313504 1.95393351890903e-11 84.6519918440728 19.3155734810259 4.38257719488517 2.16056456292357e-05 -100.322972022606 37.6259180771377 -2.66632622270987 0.00848738046640135 ZNF766 other 2.37754630580851e-07 1 0.212253862661612 4.38257719488517 -2.66632622270987 4.90967524462586e-13 271.875694287366 38.6176003000679 7.04020167423215 6.18472934279651e-11 -126.123491417226 144.362411632949 -0.873658800726486 0.383682281171982 RYR1 other 6.29322172856142e-09 1 8.10879864134051e-07 7.04020167423215 -0.873658800726486 1.80009391926448e-10 637.502403610321 106.631984176879 5.97852894261862 1.61481244253689e-08 -192.484338925408 208.847899950101 -0.921648429174519 0.358211939778387 SRGAP3 other 2.10682992310715e-06 1 0.000194681788072247 5.97852894261862 -0.921648429174519 1.88892088248937e-06 78.7069296779021 15.040991217483 5.23282864406014 5.8301541970992e-07 23.8220979318116 57.2982486838334 0.415756126566099 0.678211699667507 FAM217B other 0.016805729091508 1 0.00646564100458301 5.23282864406014 0.415756126566099 4.20669652569581e-10 6319.31164441631 1118.98436871807 5.64736364606756 8.48921227141023e-08 -6465.80309281847 3352.04168712878 -1.92891488123372 0.0557223096455396 TUBB essential 4.84274904038102e-06 1 0.000989587474478291 5.64736364606756 -1.92891488123372 1.07985420018336e-10 264.82699852869 60.3610996677322 4.38737862607664 2.08832282916681e-05 -243.50248721362 107.390286772935 -2.26745355218652 0.024718155011209 LCOR other 1.27714356255686e-06 1 0.205616265759764 4.38737862607664 -2.26745355218652 5.81234499250743e-33 936.655538067326 78.0486217162813 12.000923494488 7.0061099245604e-24 -1008.53691937451 285.957137050267 -3.52688144026711 0.000553356144472238 SUPT5H essential 8.44184986711779e-29 1 1.01091160101482e-19 12.000923494488 -3.52688144026711 1.21117305042244e-11 228.174127768041 34.1086355856052 6.68962929330241 3.96484449304624e-10 47.9287876374067 49.9283249605305 0.959951844474967 0.338594010888627 XPNPEP3 other 1.48477704251287e-07 1 5.06310641762005e-06 6.68962929330241 0.959951844474967 0.475539394885761 -24.6495445605184 27.4837980594501 -0.89687547940787 0.37116735004391 -101.956394623252 93.4296392380996 -1.0912639228267 0.276839346390648 SFTA2 other 1 1 1 -0.89687547940787 -1.0912639228267 0.00757919075198943 171.187923355213 753.505570169858 0.227188663405134 0.820590565672598 -4723.60507975684 1769.44889175502 -2.66953462276707 0.00844411962945571 PPIA essential 1 1 1 0.227188663405134 -2.66953462276707 0.0137229779541164 25.0450696749687 11.796010340995 2.12318139362161 0.0353164678287229 -12.7677471389452 23.7970074973691 -0.536527424314033 0.592358381147126 ZNF471 other 1 1 1 2.12318139362161 -0.536527424314033 1.31631752409851e-08 39.0783574931505 8.59851037039394 4.54478227155527 1.09615994237628e-05 -19.4356506098571 16.674979557053 -1.16555768739377 0.245572346927738 ZNF836 other 0.000139424352152514 1 0.110920424569055 4.54478227155527 -1.16555768739377 8.73559928772061e-10 76.0469706661792 16.4667534704639 4.61821274014841 8.1150616682275e-06 -129.643074720522 51.9584313576432 -2.49513065219685 0.0136457108043729 ZNF493 other 9.89044551355728e-06 1 0.0830385416165986 4.61821274014841 -2.49513065219685 2.04710118934742e-07 80.9640195208517 15.6850930286244 5.16184503165503 7.91919606401935e-07 -112.618153585545 64.184790386176 -1.75459252741909 0.0814413617629936 GTF2IRD2 other 0.00198609757390487 1 0.00870319647435726 5.16184503165503 -1.75459252741909 1.48518467335236e-11 39.9300154094511 6.92967005656338 5.76218132804631 4.95697091743999e-08 -43.223596027786 20.3900501205822 -2.11983765474686 0.0357589389363586 SUPT3H other 1.81489567083658e-07 1 0.00058526955622214 5.76218132804631 -2.11983765474686 3.7464399851141e-08 156.643784540843 30.9382824187503 5.06310539223432 1.17819598139682e-06 -157.36467559997 93.2029598638397 -1.68840856373944 0.0933834074794347 NIF3L1 other 0.000384609528871814 1 0.0128223068655416 5.06310539223432 -1.68840856373944 0.112086885728261 12.4819907831062 8.17229670230267 1.5273540887948 0.128751223270598 -9.69740063809262 17.2828700028728 -0.561098974677277 0.575556314926535 ATP2A1 other 1 1 1 1.5273540887948 -0.561098974677277 2.41361381944573e-11 925.286512879701 168.62649777689 5.48719522185624 1.63009952681529e-07 -366.701838741763 255.592156064383 -1.43471475959298 0.153382995090415 IARS essential 2.92650675607795e-07 1 0.00187184328664199 5.48719522185624 -1.43471475959298 2.13061324410524e-07 50.2688588007735 11.2300469806521 4.47628214622611 1.45284168335599e-05 -13.4690522243715 17.1900400532253 -0.783538152480591 0.434491582418873 MFSD14C other 0.00206368681032498 1 0.145080770499929 4.47628214622611 -0.783538152480591 1.75825571930773e-08 686.648139786887 112.15664714498 6.12222420396796 7.80271289574495e-09 -259.072241285895 447.178000398382 -0.579349254782418 0.563228423435582 POM121 other 0.000184845423770821 1 9.54115732891693e-05 6.12222420396796 -0.579349254782418 8.12661699192036e-16 593.626138742029 77.3336204753003 7.67617156798742 1.75916139626887e-12 -507.537679809333 215.275241891877 -2.35762215547409 0.0196494321982326 ZBTB44 other 1.10465104771173e-11 1 2.38032128529141e-08 7.67617156798742 -2.35762215547409 0.756825439064811 -0.642510732878415 11.3978763987618 -0.0563710914559674 0.95511973458435 25.8197136167481 36.9863986178782 0.698086717863566 0.48618256789181 GIMAP5 other 1 1 1 -0.0563710914559674 0.698086717863566 0.000129438915351781 34.5272699260477 9.26073430551325 3.72835120704114 0.000271433533510409 8.35732847165159 19.543173725874 0.427634149339163 0.669522725859863 STK31 other 0.935066724501268 1 1 3.72835120704114 0.427634149339163 0.0105887516072844 -1.63286655683692 2.55737130675849 -0.638494125793021 0.524082372085281 -12.5190691927512 4.51319895161992 -2.77387930976493 0.00621110852580871 CGB7 other 1 1 1 -0.638494125793021 -2.77387930976493 2.15981819096225e-06 34.7786973929184 8.87671826390406 3.91796792000723 0.000133928370537023 -33.2501487433248 19.5735840757511 -1.69872561992962 0.0913902543179308 ZKSCAN7 other 0.0191057517172521 1 1 3.91796792000723 -1.69872561992962 0.865118301231437 113.261593862026 359.287158224416 0.315239749791673 0.753017756907643 591.629077519504 1153.96577904052 0.512692047082558 0.608920915677258 CD55 other 1 1 1 0.315239749791673 0.512692047082558 0.764293145510783 2.38307732518381 25.4059149737967 0.0938000984275388 0.925390676456011 -71.7493264707065 102.006328476047 -0.703381128824319 0.482887249382242 CPNE4 other 1 1 1 0.0938000984275388 -0.703381128824319 8.95854631578654e-26 24.4679234288598 2.35746241732053 10.3789240706835 2.19753949819077e-19 -31.4785329115438 9.77884239476983 -3.21904491766633 0.00157458865012283 ZNF565 other 1.29218072058905e-21 1 3.14138271266371e-15 10.3789240706835 -3.21904491766633 0.207299279903702 23.2114547038327 13.0484964622122 1.77886048182272 0.0771854578874053 20.7615055168408 18.1634617101996 1.14303682018843 0.254752313258488 NTNG2 other 1 1 1 1.77886048182272 1.14303682018843 0.131329619166347 6.80703623500808 3.99293171671688 1.70477151074475 0.0903212108335723 25.2770837566009 14.3462698052992 1.76192725354043 0.0801323675529417 ELAVL3 other 1 1 1 1.70477151074475 1.76192725354043 5.34409869388642e-07 222.532818335294 64.2001256571799 3.46623649186591 0.000684128673605987 -159.82979485343 87.2118980059161 -1.83266043404522 0.0687844162203345 WDR5 essential 0.00498925054061236 1 1 3.46623649186591 -1.83266043404522 2.90162247737388e-13 570.588659508777 92.8832438040498 6.14307420951526 6.46054029006341e-09 -51.0165430164519 179.676362841923 -0.283935750977637 0.776836121895054 LONP1 essential 3.74077169783041e-09 1 7.93031320605284e-05 6.14307420951526 -0.283935750977637 4.42913031869959e-11 777.591728452068 107.333911512086 7.24460440784838 1.98961232649881e-11 45.3367318934643 346.404445214505 0.130878031502715 0.896043722798591 TRRAP essential 5.31696379388348e-07 1 2.63743010000682e-07 7.24460440784838 0.130878031502715 0.0581276505336294 13.6018053562888 10.9104234281527 1.24667987872876 0.214395583739043 -39.5091762314682 29.9610731834933 -1.31868361288324 0.189219982857756 FUT4 other 1 1 1 1.24667987872876 -1.31868361288324 1.71372536829975e-07 112.885081632465 21.3361860839505 5.29078070411932 4.09027793712253e-07 -25.9453458253641 81.3980307175905 -0.318746603531247 0.750347786962254 ASB13 other 0.00167328144960788 1 0.00458192934516465 5.29078070411932 -0.318746603531247 2.33686340481044e-06 28.9119764845648 5.92332815951084 4.8810357464565 2.58613109719558e-06 17.4668734677057 12.3423382126969 1.41519971067856 0.159003095516983 SLC35F1 other 0.0205901034597848 1 0.027516434874161 4.8810357464565 1.41519971067856 0.000205443948529054 42.5808897876643 10.3117799056111 4.12934432051776 7.55354722416856e-05 4.55401078530506 38.0033756105812 0.119831744210562 0.904856854810465 ZNF34 other 1 1 0.6999872212637 4.12934432051776 0.119831744210562 0.00403106553097321 2.94031229097461 1.16946164200945 2.51424432008078 0.0129837914564968 -4.74409387365326 4.54837125528038 -1.04303136384165 0.298611863045047 ZNF781 other 1 1 1 2.51424432008078 -1.04303136384165 4.15104825517378e-11 91.4770203286448 22.894655830056 3.99556215248076 0.00010200820935942 -136.38391381904 43.7368122350809 -3.11828656112361 0.00219174989115484 ZNF140 other 4.9899751075444e-07 1 0.932661058173181 3.99556215248076 -3.11828656112361 1.01979647024325e-07 24.3639384855988 4.07047950492966 5.9855204911589 1.50753998429591e-08 28.3958686302621 20.3138564965091 1.3978571048359 0.164206076133906 INCA1 other 0.00101413249718388 1 0.000182035453103731 5.9855204911589 1.3978571048359 0.00337270138006259 65.7173559689363 24.2495163858117 2.71004810666605 0.0074853325661614 -48.1176352092913 43.6217260010302 -1.10306582568867 0.271708248356899 ZNF774 other 1 1 1 2.71004810666605 -1.10306582568867 0.000544155770323892 125.695654937676 37.7255843334802 3.33184116716584 0.00108174163950598 -197.357417349044 181.926413188298 -1.08482003184867 0.27970776990206 PTPN1 other 1 1 1 3.33184116716584 -1.08482003184867 0.0141185230469762 262.228640776699 89.6372418630618 2.92544298916854 0.00396724664105283 117.345631067961 143.52141133663 0.817617594302541 0.414855360634546 EVL other 1 1 1 2.92544298916854 0.817617594302541 0.000173167158259183 13.8538504133967 5.00856832911624 2.7660300315482 0.00645189262315671 -13.4593063591173 10.5683018061562 -1.2735543142113 0.204962346306984 NOXO1 other 1 1 1 2.7660300315482 -1.2735543142113 0.00152459090635607 352.141747738522 105.227916200473 3.34646698759715 0.00103922787587824 -229.093778801843 350.438493525701 -0.653734629711963 0.514304111166198 EPHB4 other 1 1 1 3.34646698759715 -0.653734629711963 1.63142960989502e-10 44.0156687185225 9.27001903758888 4.74817457656171 4.63628103131694e-06 -59.1604263112377 23.7966214296391 -2.48608511448404 0.0139764216760684 ZNF765 other 1.91334064648488e-06 1 0.0484769544634499 4.74817457656171 -2.48608511448404 5.72092588661372e-06 24.9930760333002 6.28895392502173 3.97412293543141 0.000107981604235199 -27.2561867678924 19.6343178560333 -1.38819117464359 0.167070823568278 ZNF124 other 0.0483589865195458 1 0.983820396186901 3.97412293543141 -1.38819117464359 2.50740833669843e-10 1537.26790756642 300.20740462059 5.12068617864125 9.03156022545789e-07 -461.713651818124 445.775469760708 -1.03575383379882 0.301951257087763 XRCC6 essential 2.91586515474661e-06 1 0.00989317107096658 5.12068617864125 -1.03575383379882 8.53642241407917e-07 377.219172979888 83.3001970959834 4.5284307376276 1.21416521597279e-05 -30.9674195679364 113.64471796363 -0.27249325901664 0.785622583190623 PPP1R26 other 0.00783131392267623 1 0.122375712117897 4.5284307376276 -0.27249325901664 1.36288215087292e-10 199.663200584901 27.4812278005971 7.26543959511747 1.81180002936962e-11 102.381273160154 111.281684213791 0.920019083854468 0.359020567958654 TSC22D2 other 1.60383971514725e-06 1 2.40371509896468e-07 7.26543959511747 0.920019083854468 1.37495152101785e-09 192.458760505588 29.4883592690391 6.52660118352727 9.06860951365454e-10 138.585895367043 49.8260960764452 2.78139180630204 0.00608464948334117 NPIPB15 other 1.54145815021311e-05 1 1.14600018424052e-05 6.52660118352727 2.78139180630204 4.38455499363577e-13 36.1494546321939 4.97794725032355 7.26191998716826 2.012496531205e-11 -15.4027686297883 19.5930442414615 -0.78613453019179 0.433045535028362 ZNF569 other 5.62757633433151e-09 1 2.66736290245911e-07 7.26191998716826 -0.78613453019179 2.7602005268144e-08 154.711487776061 32.3699684264607 4.77947601733193 4.11081443493058e-06 -283.529173861674 128.564810128603 -2.2053404316318 0.0289319502078528 YRDC essential 0.000286011978588508 1 0.0431388866801615 4.77947601733193 -2.2053404316318 2.34756360365602e-09 240.781632653061 35.9728086705236 6.69343433420475 5.55613712161382e-10 91.6142857142856 109.299838089606 0.838192327779836 0.403426529710244 ZNF777 other 2.59734437108502e-05 1 7.07129571467791e-06 6.69343433420475 0.838192327779836 1.16863885701742e-17 245.002447210907 24.3260541778763 10.0716065753783 1.35197583228553e-18 92.1854476681354 96.4377327014756 0.955906418429566 0.340637353642309 PIK3R4 other 1.6235899640543e-13 1 1.92629516584042e-14 10.0716065753783 0.955906418429566 6.86243552426504e-14 140.3448015681 16.422290115288 8.54599453443152 1.61620083478083e-14 59.9985319565983 52.7570928126387 1.13726001107902 0.257305439057418 ZNF775 other 8.99322175454933e-10 1 2.24280189842536e-10 8.54599453443152 1.13726001107902 1.73503350486022e-10 158.383112944316 29.9714214531286 5.28447118172247 4.46549672209601e-07 -71.9443042581585 57.1425409633928 -1.25903229092049 0.210014315095556 ZNF605 other 2.03224474424278e-06 1 0.00499197878563113 5.28447118172247 -1.25903229092049 0.11861268377706 262.273541369081 456.325057124586 0.57475156639815 0.566437614112253 -2073.75177453027 1244.20203136431 -1.6667323491317 0.0979387303648523 MYL6B other 1 1 1 0.57475156639815 -1.6667323491317 7.20667366357293e-09 16.6452108501684 5.08447276447586 3.2737338995038 0.00131592299373505 -83.5230842233821 22.4422620262612 -3.72168741839153 0.000278672560865877 ZNF799 other 7.75005685780633e-05 1 1 3.2737338995038 -3.72168741839153 8.09785513876499e-09 185.671168307556 51.3789362718361 3.61376045866745 0.000415419162468233 -113.844013751683 76.6388143576985 -1.48546157330065 0.139592493769139 SIAH1 other 8.68171049426995e-05 1 1 3.61376045866745 -1.48546157330065 9.15349873475815e-05 119.835110398915 32.1808001385564 3.72380767050409 0.000277135766240839 -102.982469453476 116.039590730454 -0.887477013708978 0.37624291837523 C20orf96 other 0.674612856751675 1 1 3.72380767050409 -0.887477013708978 0.0409180586399353 27.7123727182155 17.2383739059904 1.60759784358693 0.109932495553497 -61.6025599891926 52.6006307759216 -1.17113728638767 0.243317983292654 ESRRG other 1 1 1 1.60759784358693 -1.17113728638767 5.95036040888708e-11 469.983372457832 85.81765946464 5.47653449639328 1.86430624759874e-07 -600.75017417428 194.525681374952 -3.08828207117971 0.00241315324515293 IPO4 other 7.10770550841562e-07 1 0.00213313920850248 5.47653449639328 -3.08828207117971 1.73599146741202e-12 2977.11679592577 404.030496957012 7.36854474686481 1.17673196537007e-11 560.170118687458 928.758656619047 0.603138516874385 0.547352344431601 NCOR2 other 2.18734924893914e-08 1 1.56728930467639e-07 7.36854474686481 0.603138516874385 0.000235848581376963 67.8689516129031 51.9746481958864 1.30580877348343 0.193603468176496 -319.351434062028 109.986100559582 -2.90356174495911 0.00424311457281586 SULT1A1 other 1 1 1 1.30580877348343 -2.90356174495911 0.000113458761692067 5.90636405303096 2.37554090795391 2.48632386554783 0.0139814817565804 -5.74891782240404 4.1260668223988 -1.3933167032573 0.165544902544411 ARL9 other 0.827454749020244 1 1 2.48632386554783 -1.3933167032573 5.3850371124501e-10 537.173993324337 87.9147811782883 6.11016698358113 7.46235862164578e-09 -340.284070733613 259.971704377903 -1.30892733710344 0.19245951153217 PRPF40A essential 6.16371347891039e-06 1 9.13392695289444e-05 6.11016698358113 -1.30892733710344 6.94420560163396e-08 87.4462052302446 16.8647330584622 5.18515205233959 7.07562608404555e-07 -127.218590108016 61.4472799315438 -2.07036975842943 0.0401791203152706 GDAP2 other 0.000700462019036818 1 0.00780300044548544 5.18515205233959 -2.07036975842943 4.84045227001239e-16 240.033340566346 56.5209047444009 4.2468064099792 3.74970742588708e-05 -558.940588043832 111.699835596932 -5.00395175209355 1.52583281646742e-06 ANAPC7 other 6.6023768962969e-12 0.0222512199625444 0.358996988954429 4.2468064099792 -5.00395175209355 0.522815409436637 -3.62314958559953 22.7911079938198 -0.158972068693721 0.873909080436315 -98.1649715266208 86.3151637441127 -1.13728535367943 0.257269407424481 TPK1 other 1 1 1 -0.158972068693721 -1.13728535367943 8.97080247466885e-06 174.516579971704 40.7710167171531 4.28040784909544 3.30092539969914e-05 -212.36181714519 165.060987686889 -1.28656577257388 0.200214679457427 SLC6A9 other 0.0744756021447008 1 0.318143190023003 4.28040784909544 -1.28656577257388 0.001514200759824 207.962409477543 101.172835466464 2.05551627093101 0.0415403403681192 -242.291739656511 191.638158397549 -1.26431886886474 0.208050875388668 AFAP1 other 1 1 1 2.05551627093101 -1.26431886886474 4.09909692409655e-06 1525.12313879856 575.235107162012 2.6513039969395 0.00902326809737445 -4518.98026128131 1409.7778173974 -3.20545564380054 0.00169993282349481 NACA essential 0.0352030443841412 1 1 2.6513039969395 -3.20545564380054 0.257559612398147 28.7943916349792 139.32240488371 0.206674523448065 0.836570903766492 -956.555703422073 602.903411072744 -1.58658200609626 0.114912769983716 MYO18A other 1 1 1 0.206674523448065 -1.58658200609626 0.618160055837756 -10.1055272721976 11.7951641363331 -0.85675172938621 0.392922014286241 24.1305635064566 48.7468757856008 0.495017642004136 0.621297806573261 SPTSSB other 1 1 1 -0.85675172938621 0.495017642004136 5.07821834260508e-09 40.0368193069306 7.20533124775905 5.55655499105369 1.21262976120067e-07 -78.3125000000001 38.6281965228908 -2.02734031224038 0.0443866893601511 BORCS6 other 5.51240601089782e-05 1 0.00140301263370918 5.55655499105369 -2.02734031224038 9.56092042575467e-13 861.213527469182 108.577614146245 7.93177796584477 5.32425380053902e-13 148.332343712684 196.529740295905 0.754757745516519 0.45161846398806 MAN2A2 other 1.21490615850065e-08 1 7.25962005703496e-09 7.93177796584477 0.754757745516519 0.825900852435828 3.45261508915551 46.5175337319768 0.0742218000861499 0.940931487656996 -114.088668414265 186.609677825129 -0.611375946542156 0.541863997280396 MME other 1 1 1 0.0742218000861499 -0.611375946542156 0.675245599777392 -4.76824186603043 23.2439830514481 -0.205138760232118 0.837775004223186 -41.1303545300026 49.495238186021 -0.830996193521078 0.40745402314488 CACNA1H other 1 1 1 -0.205138760232118 -0.830996193521078 0.768955957439012 82.1127279689818 114.122893926631 0.719511441952846 0.47293797248454 60.4121391986984 531.241937425265 0.113718693767841 0.909611850327491 SULF2 other 1 1 1 0.719511441952846 0.113718693767841 0.548716392757786 10.5934218575493 22.0532447689304 0.480356608224554 0.631646751094494 -23.9663432128005 49.4272158949753 -0.48488151272216 0.628440564661755 LAMA2 other 1 1 1 0.480356608224554 -0.48488151272216 0.000201672740376945 3003.00600226502 1123.77951165423 2.67223772201053 0.00839744783098425 -1733.42926387315 1789.7217476045 -0.968546795720232 0.334384117016285 PLXNB2 other 1 1 1 2.67223772201053 -0.968546795720232 0.0306419454674491 132.812403039673 94.1968984404449 1.40994454423192 0.160697449285475 -224.255366183104 210.375048345362 -1.06597891692439 0.28820490843406 AJAP1 other 1 1 1 1.40994454423192 -1.06597891692439 5.12069414782759e-06 63.4874326035183 12.9125304098353 4.91673053913283 2.23372646318896e-06 8.38011172986519 40.3323164621405 0.207776603601023 0.835677919332289 XRCC2 other 0.0435207795623867 1 0.0238763021650268 4.91673053913283 0.207776603601023 2.86882444329627e-05 342.122108156266 77.985275336284 4.38700904345064 2.15414694138142e-05 129.432916212958 150.294870510191 0.861193171620464 0.390506191987127 MYO6 other 0.225575665976386 1 0.21173110286838 4.38700904345064 0.861193171620464 0.000937273169571406 215.183832827762 64.1394960599635 3.35493488484206 0.00100106459644612 12.8057402422091 107.093213647634 0.119575646355553 0.904976179427462 MKL1 other 1 1 1 3.35493488484206 0.119575646355553 2.70648828675528e-22 1186.45002417462 137.839433220009 8.60747898085808 7.8707183290495e-15 -314.866412005981 284.074155556363 -1.10839513502843 0.269408113734441 HDAC2 other 3.86351202934317e-18 1 1.09623364887001e-10 8.60747898085808 -1.10839513502843 2.23452244009285e-08 25.6934235976788 6.57186813684434 3.90960729318836 0.000137216487049097 -21.077218326886 10.0596797761846 -2.09521762082173 0.037756726744969 ZNF782 other 0.000233127726174887 1 1 3.90960729318836 -2.09521762082173 0.530782169804786 13.8597076981228 12.4197963698061 1.11593679038227 0.266176240566705 18.7336525135442 30.1649152109665 0.621041112912975 0.535484778542776 POTEF other 1 1 1 1.11593679038227 0.621041112912975 1.24741100264592e-07 20.3717884297042 5.34666212798554 3.81018810279296 0.000202093255352429 -38.6761500631521 17.787659567249 -2.17432484115918 0.0312483871312759 ZNF846 other 0.00123106991851126 1 1 3.81018810279296 -2.17432484115918 0.412378384395967 2.37376928703636 56.0457397871351 0.0423541431704189 0.966270894384111 -178.978423245064 156.178707418819 -1.14598479013599 0.253567605291043 MMP1 other 1 1 1 0.0423541431704189 -1.14598479013599 0.839848234493656 19.4547970479703 59.5347204041346 0.326780690593773 0.744271797278764 -12.3575142569611 89.3263257348234 -0.138341235411898 0.890149151636482 ADH1B other 1 1 1 0.326780690593773 -0.138341235411898 0.000276881143720063 345.525802614665 101.159969152587 3.41563768266361 0.000815018680289591 159.481136755191 186.091916506337 0.8570019576845 0.392784143935675 TCF4 other 1 1 1 3.41563768266361 0.8570019576845 0.00962327875640046 -6.93159656527428 29.5461993197974 -0.234601969960643 0.814831344400724 -284.279599039441 94.3765972227378 -3.0121831831732 0.00303587697962152 SDHAF3 other 1 1 1 -0.234601969960643 -3.0121831831732 0.180158700031453 15.5061776691119 37.1714763789425 0.417152590632535 0.677136649906065 -99.1044172779131 72.3142723526585 -1.37046829144053 0.172497063175921 HRH1 other 1 1 1 0.417152590632535 -1.37046829144053 9.30491194565702e-08 744.551267113313 161.46514233375 4.61121983576071 9.81473511743668e-06 -307.764423159302 250.701228148713 -1.22761434170853 0.221917131000585 RABL6 other 0.000928351064818201 1 0.0997667824687438 4.61121983576071 -1.22761434170853 1.2540227346154e-22 87.2167943819029 8.71770896422371 10.0045544924508 2.27674648104831e-18 -67.5608951856232 37.5019273269862 -1.80153128122049 0.0736276403652125 ZNF136 other 1.7930017059531e-18 1 3.24117629042037e-14 10.0045544924508 -1.80153128122049 2.20405326692189e-09 75.237286036315 13.5338293208286 5.55920163116911 1.1574031483771e-07 -95.6390340773032 44.6115328912465 -2.14381860202946 0.0336070029550232 ZKSCAN5 other 2.4423510645706e-05 1 0.00134085154739487 5.55920163116911 -2.14381860202946 4.63598092086289e-08 41.4121212121213 11.167791301567 3.70817470472524 0.000291428043731533 -73.031857031857 24.6080914605923 -2.96779850435826 0.00348223563011166 ZNF502 other 0.000472591895072763 1 1 3.70817470472524 -2.96779850435826 0.000114209746774957 123.447100649748 32.1644681780978 3.83799601368223 0.000185126531508158 -129.162498467574 118.343011632714 -1.09142480561877 0.276908779935837 TTC30B other 0.832703263736212 1 1 3.83799601368223 -1.09142480561877 8.80452684390589e-10 263.6347828349 39.7801114772515 6.62730125795804 6.26452859225193e-10 68.7280600106891 68.3760721572427 1.00514782207198 0.316500102406478 TECPR2 other 9.96408302924829e-06 1 7.95908357645608e-06 6.62730125795804 1.00514782207198 0.411908295513522 -5.1479151967786 11.767854690139 -0.437455707291519 0.662389810957387 -30.1229078831891 22.9557507623604 -1.31221619345076 0.191387132678867 LINC00173 other 1 1 1 -0.437455707291519 -1.31221619345076 2.67764990670167e-09 200.083869293645 37.918697249492 5.27665462706067 4.66418785840468e-07 -75.1107074676105 62.904442013357 -1.19404457083749 0.234396932531415 ZFP62 other 2.95425114206396e-05 1 0.00520756574390882 5.27665462706067 -1.19404457083749 0.000140904020645247 95.7171355196038 28.8084711822132 3.32253436547168 0.0011098615513654 -84.6541060629373 78.6803991896619 -1.0759236980849 0.283611975023677 ERI2 other 1 1 1 3.32253436547168 -1.0759236980849 2.16137220525295e-06 326.047908650168 167.37314908741 1.94802995837696 0.0532416244688496 -1179.5286877139 393.065582132222 -3.0008444934696 0.00314459935512076 TOMM7 other 0.0191173371554623 1 1 1.94802995837696 -3.0008444934696 2.27391899268812e-06 89.43327685505 18.3810977957133 4.86550247700149 2.82811685812275e-06 -58.4960583513447 112.199314025913 -0.521358431280914 0.602875889831336 HSH2D other 0.02006506119148 1 0.0300119760983986 4.86550247700149 -0.521358431280914 4.0844588207468e-13 84.2636874815034 11.0047951992406 7.65699733215557 1.86794045726803e-12 -114.522886455558 61.7760062873902 -1.85384088966163 0.0656503132533295 TRPV1 other 5.24648735524926e-09 1 2.52620267440928e-08 7.65699733215557 -1.85384088966163 0.00293889548740628 118.150432813831 44.1046785672553 2.67886393579909 0.00825935827796538 -102.91821489595 102.104445643561 -1.0079699688614 0.315183381820355 ZNF33B other 1 1 1 2.67886393579909 -1.0079699688614 4.97799431323402e-06 415.684747920088 89.3767627102066 4.65092643003748 8.82439782085361e-06 -17.9634470290893 307.095035201366 -0.0584947490841409 0.953455192943411 ZNF512B other 0.0423328636397421 1 0.0900529797618111 4.65092643003748 -0.0584947490841409 7.46138849865264e-08 363.247641765153 64.0367896631774 5.67248364066614 6.71601386733281e-08 -504.082727962701 257.749735655774 -1.95570609094981 0.052297866381818 AMZ2 other 0.000750615682964456 1 0.000787452625944772 5.67248364066614 -1.95570609094981 7.22432611712873e-10 99.3203052179474 19.6413982005963 5.05668202454812 1.19785723608879e-06 -121.48960675013 61.9755583275319 -1.96028256991368 0.0517673998810172 ZNF431 other 8.21478122778707e-06 1 0.0130254995852295 5.05668202454812 -1.96028256991368 4.28162851916757e-14 685.48829920382 79.2977030949194 8.64449123303471 8.80902165805294e-15 -16.0554906972083 303.68013838319 -0.0528697424292831 0.957907963670649 NF1 ts 5.64233006255903e-10 1 1.22612772458439e-10 8.64449123303471 -0.0528697424292831 1.75654263427475e-05 47.3451422619801 11.6686142855694 4.05747770071823 7.88516963218618e-05 0.930757400250952 22.9209448430174 0.0406072876413075 0.967661915217687 ZNF418 other 0.141313854927403 1 0.729457042673544 4.05747770071823 0.0406072876413075 0.00374457830922879 226.967463822589 86.8005726438901 2.61481528185017 0.00980887495588332 -69.3491981457115 130.060782691859 -0.533206064967441 0.594654650131789 DAPK1 other 1 1 1 2.61481528185017 -0.533206064967441 0.102158095683803 -515.012560125709 260.002936012155 -1.98079517110389 0.0493500727951368 -1258.78734727884 765.862396769115 -1.6436207765118 0.102242995874417 HLA-DQA1 other 1 1 1 -1.98079517110389 -1.6436207765118 0.211198617535499 4.11248345831502 100.229088959202 0.0410308374646504 0.967323114406884 -245.527348919277 160.541026767896 -1.52937447743031 0.128171231409248 COL27A1 other 1 1 1 0.0410308374646504 -1.52937447743031 0.563070137869107 74.2448384459985 79.7852583488593 0.930558351034781 0.353538509062462 -10.5752932715085 124.896299314337 -0.0846725910180317 0.932631661064999 GM2A other 1 1 1 0.930558351034781 -0.0846725910180317 0.135802300382337 7.08282801028162 3.77240936970393 1.87753430663266 0.062399493327291 1.75187099706037 10.7650454300203 0.162736981320577 0.87094602733362 HIST1H2AI other 1 1 1 1.87753430663266 0.162736981320577 0.00932929097047844 84.6402354088315 50.7283029548937 1.66850122078973 0.0973023203502314 -429.827552583925 233.406499439126 -1.84154063240225 0.0675174786254274 SNHG17 other 1 1 1 1.66850122078973 -1.84154063240225 4.9197321178245e-16 62.6948748815409 8.96697490865511 6.99175312970114 8.34203715576182e-11 -93.7997208206337 34.728944487081 -2.70090906032364 0.00771070336724249 ZNF700 other 6.70903868907727e-12 1 1.08980373402872e-06 6.99175312970114 -2.70090906032364 1.49666638075249e-07 906.240593764726 186.136040119256 4.86870029675125 2.74446651398818e-06 -139.582740147324 258.857190293701 -0.539226822283561 0.590504061250425 TLE1 other 0.00146837938615626 1 0.0291572122446105 4.86870029675125 -0.539226822283561 5.09828426998876e-13 353.670365033196 52.8458359153404 6.69249258540976 3.84406456566517e-10 51.6495716672708 83.5400337975286 0.618261321182262 0.537316409145859 MAML3 other 6.5309021498556e-09 1 4.91233010846352e-06 6.69249258540976 0.618261321182262 0.358858625356154 14.0567726779906 10.7076119624602 1.31278316092068 0.191301826101862 1.40684495843875 30.6559738263953 0.0458913804665188 0.963459108418968 HIST1H2AG other 1 1 1 1.31278316092068 0.0458913804665188 5.98063835865888e-13 167.417771938273 26.3852491779371 6.34512756765111 2.42204494599219e-09 -79.920190832757 44.2129972031577 -1.80761757601561 0.0726433255539655 STRN3 other 7.64564807770951e-09 1 3.01786800270627e-05 6.34512756765111 -1.80761757601561 0.000323931565191848 35.8724505723201 14.6136110458044 2.45472870872796 0.0152582167202614 -68.3958723551858 33.0912133380191 -2.06688922695393 0.0404868221350438 ZNF239 other 1 1 1 2.45472870872796 -2.06688922695393 2.06339937918157e-11 40.6896613733193 6.53022343504296 6.23097536831091 4.33976772321681e-09 -23.0964053191685 18.5903114249813 -1.24238937106411 0.216006268587394 ZSCAN16 other 2.50847462527103e-07 1 5.3583112078558e-05 6.23097536831091 -1.24238937106411 0.000158868722736414 115.876592620111 32.2129845367488 3.59720138591684 0.000430499874671961 1.33707822775838 45.4712505571646 0.0294049143442285 0.976578998988909 MVB12B other 1 1 1 3.59720138591684 0.0294049143442285 5.35818185805721e-10 390.83392979363 89.7884121692512 4.35283262451404 2.43867158474651e-05 -773.809176803791 258.437081398101 -2.99418787976406 0.00320698980283366 C6orf106 other 6.13351077291809e-06 1 0.238233827113886 4.35283262451404 -2.99418787976406 1.26688180426583e-18 102.985274571122 11.0579837207427 9.31320547867513 1.52614930589811e-16 -18.4600156167048 46.7533351575477 -0.394838476324714 0.693526726180332 ZNF709 other 1.77464803141558e-14 1 2.15156529145516e-12 9.31320547867513 -0.394838476324714 0.192604525271738 4.66786079836235 2.93326217888763 1.591354783067 0.113635039305834 -1.17548618219037 7.09963721034771 -0.165569894258414 0.868718382473493 POTEI other 1 1 1 1.591354783067 -0.165569894258414 0.00384510704299548 33.564979768204 10.2890455310141 3.26220538795652 0.00135975406901008 10.3056740575279 45.1197332666604 0.228407246927209 0.819630713183076 ADA other 1 1 1 3.26220538795652 0.228407246927209 0.000684700611692182 62.9401286491836 16.6696088157426 3.7757411913436 0.000230419924921671 -17.4481939633844 85.1715589824146 -0.204859394049449 0.837963452425007 ARID5A other 1 1 1 3.7757411913436 -0.204859394049449 0.000383974695137187 39.6831398502768 30.6688941349002 1.29392144613127 0.197642361310438 -158.689269827493 60.609617774164 -2.61821928029279 0.00972742841030209 PPTC7 other 1 1 1 1.29392144613127 -2.61821928029279 0.000262293789500619 2.63339409056025 1.36828725952786 1.92459154481124 0.0560888896749019 -4.40108403683805 1.91898393340617 -2.29344496335943 0.023148927927647 TOMM20L other 1 1 1 1.92459154481124 -2.29344496335943 2.84839375949417e-07 10.4485639167376 2.08956993123035 5.00034182181473 1.53260558068403e-06 -6.03691986400562 5.72197000661756 -1.05504220697134 0.293047769679154 RGPD4 other 0.00272249475532452 1 0.0165536728769683 5.00034182181473 -1.05504220697134 3.3276977687329e-08 186.713478116339 38.983867043017 4.78950633374337 3.89652704938945e-06 -95.7216907348533 74.6904140174836 -1.28157932974433 0.201916492403298 NHLRC2 essential 0.000342786147157176 1 0.040940809707935 4.78950633374337 -1.28157932974433 0.29334825693152 5.01748348017622 3.32526755858453 1.5088961690385 0.133442876543574 1.99392824020404 9.43345925189456 0.211367663437312 0.832889211575933 HIST1H2AD other 1 1 1 1.5088961690385 0.211367663437312 6.9207461131165e-06 27.1531351882684 9.4405370796334 2.8762277992475 0.00458791813138854 -35.3038937625373 19.0451284094311 -1.85369680915645 0.0656710624133415 ZFP28 other 0.0580027731740294 1 1 2.8762277992475 -1.85369680915645 4.79336563169969e-08 124.487733022428 23.5207899152011 5.29266803841371 4.30058980269851e-07 -207.871889377813 110.079939072184 -1.88837213328673 0.0609462879813326 KIAA1211L other 0.000488012554963346 1 0.0048127900481999 5.29266803841371 -1.88837213328673 0.193462669212119 28.9297431410122 17.2779134069101 1.67437713453536 0.0960861851371382 -3.38352513762273 44.3417536230975 -0.0763056230563749 0.939274993566121 SCN8A other 1 1 1 1.67437713453536 -0.0763056230563749 0.156338965285774 10.6072312988856 10.4946941212403 1.0107232451318 0.313714012501358 -38.4819934768822 33.1616637175821 -1.16043615316198 0.247644064706114 HIST3H2BB other 1 1 1 1.0107232451318 -1.16043615316198 3.96607002148619e-19 85.6404704620113 11.0772680900447 7.7311905576229 1.2267042871124e-12 -19.7404331365804 23.1279206350869 -0.853532552625269 0.394672727731688 KPNA5 other 5.57589784320743e-15 1 1.66328834289571e-08 7.7311905576229 -0.853532552625269 3.61363067080949e-22 63.1532784326906 5.49559762987221 11.4916125025986 2.54876888049923e-22 -4.44556913399435 29.025905775039 -0.153158670342592 0.878478992062319 ANKRD36B other 5.15592824111098e-18 1 3.66869792659059e-18 11.4916125025986 -0.153158670342592 2.14596679035406e-13 960.251353302056 143.394441496287 6.69657305598503 3.88361024264108e-10 -856.629886924095 401.12536949625 -2.13556646392096 0.0343169521944756 ARHGEF12 other 2.77623723668105e-09 1 4.96247716804678e-06 6.69657305598503 -2.13556646392096 0.0185089783171985 17.6203436928702 43.3242069476573 0.406708972518723 0.684793845990714 -219.366199767326 97.2699826091048 -2.25523017361774 0.0255467395528099 HCAR1 other 1 1 1 0.406708972518723 -2.25523017361774 0.000168425817555309 193.938040963236 50.7741956169079 3.81961818610582 0.000233300773211606 -155.352865141258 186.588292693345 -0.832597066508229 0.407076046176228 ZNF252P other 1 1 1 3.81961818610582 -0.832597066508229 0.0927951537744494 480.264972479041 235.418803710246 2.04004508097897 0.0430885901540546 632.250205672647 380.137085208269 1.66321632451685 0.0983433173811906 PDLIM7 other 1 1 1 2.04004508097897 1.66321632451685 0.00389833661244558 27.4936219796393 8.18443938784141 3.35925537190526 0.000985184686438914 28.9223248234654 18.2483423984181 1.58492887693584 0.115033830458568 TMEM26 other 1 1 1 3.35925537190526 1.58492887693584 0.00256098082022045 115.988703721439 40.4864391202211 2.86487787619505 0.00477069395481067 -133.839250178251 127.139749789861 -1.05269398751738 0.294174090944109 SRGAP1 other 1 1 1 2.86487787619505 -1.05269398751738 0.0612946045406064 68.1989908950906 58.0050502351814 1.17574229517219 0.241524155679592 -287.260025756716 179.351895101533 -1.60165592671377 0.111294371695855 FAM3C other 1 1 1 1.17574229517219 -1.60165592671377 4.08639471234616e-09 259.152074637859 49.9628919084558 5.18689100528225 7.12447676421801e-07 -147.383310466342 103.640997904253 -1.42205607285352 0.157172356041649 NOP9 essential 4.45784799169843e-05 1 0.00785331073719751 5.18689100528225 -1.42205607285352 2.21889463139633e-05 366.604947816004 82.8900673043233 4.42278501801727 1.83969621255175e-05 -126.709028659782 291.759916840971 -0.434292105755046 0.664688172992801 SLC39A10 other 0.176890280014916 1 0.182056337194121 4.42278501801727 -0.434292105755046 0.00223748757410291 102.403523668011 82.0382725797865 1.24824085695391 0.213849669553153 -527.738025622942 223.611644233334 -2.36006504684639 0.0195334012865336 CASP4 other 1 1 1 1.24824085695391 -2.36006504684639 1.01512622065842e-14 968.795758498006 142.565986008041 6.79542004109849 2.11849259408406e-10 -154.436767542546 247.902685001747 -0.62297335561919 0.534205909457122 AP2A1 other 1.35407686573627e-10 1 2.73243174784961e-06 6.79542004109849 -0.62297335561919 7.17273089029776e-27 115.077535318697 9.28139009292932 12.3987392154075 1.05415162396483e-24 -3.74864758566841 37.8950522390487 -0.0989218212979701 0.921333302740271 ZNF585A other 1.03667479557474e-22 1 1.52198411468043e-20 12.3987392154075 -0.0989218212979701 5.37938445494015e-05 85.1218789451536 21.0378237273717 4.04613519194023 8.59972156141348e-05 -17.5433616215456 47.7855005650727 -0.367127296231952 0.714082393931942 FUT11 other 0.408295280129957 1 0.792120353021796 4.04613519194023 -0.367127296231952 2.08667288487371e-07 504.578406870877 121.049946717023 4.16834885562094 5.10135703204911e-05 -321.485524715249 246.595552717076 -1.30369554995218 0.194282898655814 METTL9 other 0.00202282069459657 1 0.482231280239602 4.16834885562094 -1.30369554995218 1.24247308576933e-10 61.8166307460109 11.2861718932495 5.47720089067445 1.75079482417204e-07 -63.8435743433352 35.622700822209 -1.79221599906124 0.0750874369252526 ZNF429 other 1.46537275735635e-06 1 0.00200623578901874 5.47720089067445 -1.79221599906124 7.29674586593069e-07 32.894956327275 7.9977179019814 4.11304283677291 6.31826661285629e-05 -13.3398834782981 15.9862854701426 -0.834457979823571 0.405307193050619 ZNF470 other 0.00672905903756129 1 0.591073841632706 4.11304283677291 -0.834457979823571 1.17905698185414e-05 22.3058487575876 14.3496028374864 1.55445757002532 0.12214140620697 -163.670200041862 48.148901914676 -3.399250938929 0.000861764493136737 SERTAD1 other 0.0967298347913136 1 1 1.55445757002532 -3.399250938929 4.3385764662078e-08 76.3438371444505 14.6670999526128 5.20510785302519 6.23619436874796e-07 -14.7724484104852 41.8477566121882 -0.353004548066567 0.724577327813336 ZNF100 other 0.000443445900611099 1 0.00690533802451462 5.20510785302519 -0.353004548066567 0.000863613415742292 83.4848324206365 22.8882043712036 3.64750467387785 0.000376194045329957 -8.16929839008518 71.0642156242256 -0.11495656876427 0.908649097854938 ZNF398 other 1 1 1 3.64750467387785 -0.11495656876427 1.27096797138085e-11 98.479972255939 14.2126208796896 6.92905081262461 1.0677251849491e-10 -61.9768076989768 46.8490320673167 -1.322904763751 0.18781541247095 ZSCAN25 other 1.55668157134726e-07 1 1.39039173584072e-06 6.92905081262461 -1.322904763751 0.589443539833641 -3.55816798816387 150.47376444169 -0.0236464343227267 0.981164853049077 217.507540119123 237.523598580006 0.915730232361984 0.361221773350883 ANXA6 other 1 1 1 -0.0236464343227267 0.915730232361984 4.98700263537286e-15 45.7202726328325 6.46030450490845 7.07710799051265 5.26533413952217e-11 -50.7870541633939 25.17856214156 -2.0170752355856 0.0454715727397093 ZNF441 other 6.68956533508915e-11 1 6.91180412495075e-07 7.07710799051265 -2.0170752355856 7.66338862889114e-06 220.275771005899 83.1175240645511 2.6501724333707 0.00886867439965863 -301.563407402879 120.781532359925 -2.4967675232355 0.0135649799026125 GMFB other 0.0639586414967254 1 1 2.6501724333707 -2.4967675232355 0.0289388073912111 -40.6829134980989 23.294925200579 -1.7464281661264 0.0827836537980574 -128.708460076046 47.811722481074 -2.69198542526876 0.00791010076155747 SIGLEC15 other 1 1 1 -1.7464281661264 -2.69198542526876 2.83929124472758e-21 58.7920673874112 5.95190379750007 9.87785915022772 5.17837392854524e-18 -33.1692917875374 24.3010694593995 -1.36493136003559 0.174332154210522 ZNF420 other 4.0397435829984e-17 1 7.35898718985565e-14 9.87785915022772 -1.36493136003559 5.18929466597994e-21 33.1541377455627 3.52522988676172 9.4048158022449 8.42886091770653e-17 -22.4949030556054 13.6531566429808 -1.64759722925835 0.101528564181684 ZNF763 other 7.3719120024911e-17 1 1.19049231601687e-12 9.4048158022449 -1.64759722925835 1.53980293865916e-12 81.2351183739983 12.8101870803559 6.34144668336421 2.60777118975464e-09 -72.8250645059074 39.548634185882 -1.8414052976804 0.0675641319441772 ZMYM1 other 1.94384722976332e-08 1 3.24563202276863e-05 6.34144668336421 -1.8414052976804 0.590078205073852 -21.8261536877768 21.2234783604241 -1.02839663306447 0.305375818629122 -23.7790328769431 37.2142085419808 -0.638977256499177 0.52378696474754 DTHD1 other 1 1 1 -1.02839663306447 -0.638977256499177 0.991198621265941 0.901583493282157 8.19917616751127 0.109960253916073 0.912588859471877 2.58075310637436 22.7734703847679 0.113322785801698 0.909927196539596 HIST1H4C other 1 1 1 0.109960253916073 0.113322785801698 5.35812381249718e-13 101.835063897763 15.427280888989 6.60097295372681 6.32473017146374e-10 -71.7585538352311 43.9066329490112 -1.6343442668119 0.104242507343548 ZSCAN26 other 6.86107754190264e-09 1 8.03430473681038e-06 6.60097295372681 -1.6343442668119 0.000314309084429801 124.066432249152 30.890227033995 4.016365179596 9.6637170317798e-05 173.470551299763 140.252567131647 1.23684403677928 0.218245695084272 MAFG other 1 1 0.885776303132936 4.016365179596 1.23684403677928 0.0167444095566678 107.216392277626 120.234301689824 0.891728822563621 0.374368543515796 -381.142011133484 188.887034390612 -2.0178304580996 0.0458968647892621 ARRDC1 other 1 1 1 0.891728822563621 -2.0178304580996 7.02543557745913e-22 682.774731936373 59.2899193393822 11.5158654210354 1.71368988184623e-22 -167.876044879713 328.970908901963 -0.510306657327388 0.61057206541565 KIAA1671 other 1.00210813076877e-17 1 2.46771342985857e-18 11.5158654210354 -0.510306657327388 9.28632805388022e-07 636.22031620681 152.155715191526 4.18137639723864 4.86107581985508e-05 -147.110536993856 322.585448029724 -0.456035874812 0.649010814639708 IGF2R other 0.00849513290368963 1 0.460684155447666 4.18137639723864 -0.456035874812 0.677277896889635 -22.9284151737625 26.4993776517757 -0.865243534209041 0.38824232361898 -5.74706252796599 87.2609588915062 -0.065860639178988 0.947573648624778 GAL3ST4 other 1 1 1 -0.865243534209041 -0.065860639178988 7.08568867866865e-08 2155.1947699013 363.945224692589 5.92175586785541 2.16039792135953e-08 835.02971413921 594.142309339307 1.40543721767227 0.162001239164325 DYNC1H1 essential 0.000713953991262653 1 0.000259182938625503 5.92175586785541 1.40543721767227 0.268288265813517 -4.8984375 3.40467971720881 -1.4387366527433 0.152267682576959 -13.3540581597222 11.7904588783359 -1.13261564265826 0.259147536718032 SLC6A17 other 1 1 1 -1.4387366527433 -1.13261564265826 1.0177497301353e-11 2981.30198583354 527.935375395418 5.64709645304707 8.67584056516591e-08 -4661.08620035417 1412.9903416343 -3.2987388965186 0.00122959759609727 PCBP2 essential 1.25081441833628e-07 1 0.00101099570105878 5.64709645304707 -3.2987388965186 0.00527122216707469 125.621012045062 45.6908437392109 2.74936949648091 0.00692771231075943 -67.7601891204686 156.80624028449 -0.432126865598797 0.666451417079476 ZGPAT other 1 1 1 2.74936949648091 -0.432126865598797 0.000236555636728253 1058.26966019417 267.428500409949 3.95720597681968 0.000116054539211158 163.66140776699 428.189388838068 0.382217336611496 0.702834036272237 SLC25A29 other 1 1 1 3.95720597681968 0.382217336611496 1.75720266302193e-07 122.064573789774 21.639383071772 5.64085276298858 7.96308442374977e-08 17.8692429119721 75.0983615861152 0.237944510833056 0.812242489497256 PGAP1 other 0.0017143269180442 1 0.00092984936816126 5.64085276298858 0.237944510833056 9.82547638892274e-07 266.661237785016 56.9926078592012 4.67887411721527 6.39121758483506e-06 -269.970632060434 262.938408890982 -1.02674475440508 0.306193543800587 SRC other 0.00897065994308646 1 0.0660021039985917 4.67887411721527 -1.02674475440508 6.78505970928187e-08 33.511585891664 6.41359704369687 5.22508440479564 5.5752845368631e-07 -9.8183104701544 21.5713328799509 -0.455155484586669 0.649638413710963 ZNF682 other 0.000684748225860727 1 0.00619079594973278 5.22508440479564 -0.455155484586669 5.99288416282978e-05 78.2515674362089 19.3598083786223 4.0419598120928 8.34832082236097e-05 20.2947509113002 39.0766626423615 0.519357323245396 0.604257209342693 ZNF772 other 0.451743608194109 1 0.769798663029905 4.0419598120928 0.519357323245396 1.01357714728847e-09 73.8308704473507 11.9456111574557 6.18058544466099 5.33989197765698e-09 7.8389199870467 36.1803978402103 0.216662072696576 0.828754784659239 ZNF257 other 1.14382181071504e-05 1 6.57340702449574e-05 6.18058544466099 0.216662072696576 8.52986658438281e-08 988.419013246875 180.637809074695 5.47182795401463 1.85668350010222e-07 -545.739677425935 574.813635378116 -0.949420201326547 0.343954704942292 PCNX3 other 0.00085383964509672 1 0.00212497426586699 5.47182795401463 -0.949420201326547 3.37684434256893e-08 21.2288760667822 3.59632106541775 5.90294239046654 2.73788458044791e-08 -2.88972598231715 12.8394362359982 -0.225066422637402 0.822267928763048 ADAM32 other 0.000347747430397749 1 0.000326930797751285 5.90294239046654 -0.225066422637402 0.848877243313197 61.10427852349 110.951326400489 0.550730491521375 0.582621685323043 81.4229865771817 211.115429306639 0.385679942222116 0.700269438765277 ACSL5 other 1 1 1 0.550730491521375 0.385679942222116 8.05676724721618e-08 133.59366638954 30.7675061362125 4.34203753135207 2.53002119530673e-05 -301.809538205728 101.082617083198 -2.98577091605491 0.00328537307936443 LRRC8B other 0.000807852051878367 1 0.246930068661937 4.34203753135207 -2.98577091605491 2.29335398574743e-05 122.245711153634 29.5298829465053 4.13972894423887 5.77943464462895e-05 -105.128475209054 94.8253657328996 -1.10865351687834 0.26935408053459 ABCB8 other 0.182528043725638 1 0.542342147051981 4.13972894423887 -1.10865351687834 0.0420401894975596 8.20317970262367 3.40757275753865 2.40733809262784 0.0172762263644759 2.97038593022777 9.78522585289042 0.303558239215333 0.761882328560294 HIST1H3J other 1 1 1 2.40733809262784 0.303558239215333 3.34562570556735e-14 1361.96156599197 177.355224605418 7.67928640964525 1.64655843902724e-12 -1354.48389867579 613.8566206462 -2.20651509345934 0.0288092486045158 SND1 other 4.41555680620779e-10 1 2.22878150306727e-08 7.67928640964525 -2.20651509345934 9.14010739358164e-06 50.8617989518497 20.0395268706369 2.53807384177195 0.0121332260755613 -116.774309707121 42.7453541158279 -2.73185968680236 0.00702888418047893 ZNF785 other 0.0758080507223661 1 1 2.53807384177195 -2.73185968680236 0.0599249218053423 0.0932034573570445 9.99622680054727 0.00932386381548903 0.992572966989544 -44.0400488441713 20.9087568326554 -2.10629685909348 0.0368215174982142 SULT1A2 other 1 1 1 0.00932386381548903 -2.10629685909348 0.00289500730522761 38.9168797953963 17.1202840961965 2.27314450956116 0.0244665926542826 -28.3274190110827 28.8353848135598 -0.982383942306946 0.327524827111069 NEK5 other 1 1 1 2.27314450956116 -0.982383942306946 2.80007293749453e-10 294.56608621562 41.5443189930663 7.09040594129807 4.36670308935044e-11 149.316838405624 168.117636538084 0.888168793473366 0.375817342607024 PSMD12 essential 3.2500446585499e-06 1 5.74483458434944e-07 7.09040594129807 0.888168793473366 0.0150286609659258 6.70416428823833 4.13886089703658 1.6198090380468 0.107876729895611 -8.90279703172147 6.47538139498308 -1.37486836506944 0.171712848743862 CYSRT1 other 1 1 1 1.6198090380468 -1.37486836506944 0.00104051913148402 -14.8323170731708 10.5748539534615 -1.40260254547682 0.162748111881573 -61.7621951219513 16.6001605248297 -3.72057818534769 0.000278038315118019 SLC22A4 other 1 1 1 -1.40260254547682 -3.72057818534769 1.12246452561808e-14 144.730004925447 41.3334996721264 3.50151828597874 0.000605489854583414 -225.190862550187 75.6881963062201 -2.97524414030303 0.00340016756445511 ENTPD4 other 1.49568398038609e-10 1 1 3.50151828597874 -2.97524414030303 1.38529371378745e-05 920.904362001681 235.796465369166 3.90550537116789 0.00014251798905951 -291.941081647455 381.316853177047 -0.76561284720323 0.445125950249263 TBC1D9B other 0.112790614176574 1 1 3.90550537116789 -0.76561284720323 0.708767000148876 2.17911813241822 5.84421639524158 0.372867461614269 0.709769965227095 -8.49127246614977 16.7207210537491 -0.507829323798562 0.612314033957365 HIST1H4J other 1 1 1 0.372867461614269 -0.507829323798562 0.0106792843731479 1.09085601350241 1.58039501014696 0.690242633328094 0.491073855880519 -6.71244643833821 3.3416898646621 -2.00869820665329 0.0463055359806983 FAM110D other 1 1 1 0.690242633328094 -2.00869820665329 0.0541202278070015 -1080.06088755673 492.546039478751 -2.19281204392534 0.0298113727689217 -1560.66179444862 830.842916814072 -1.87840777464059 0.0622034073695109 SERPINA1 other 1 1 1 -2.19281204392534 -1.87840777464059 0.855242101234757 -14.6372576566451 35.1979369021565 -0.415855557026933 0.678171155242978 -40.9242413599326 75.3506175674596 -0.543117530832367 0.587937932604313 TPSB2 other 1 1 1 -0.415855557026933 -0.543117530832367 3.81847115926027e-05 299.063730955036 85.1686818392313 3.51142843233812 0.000586972859253681 -350.142512077294 299.527744612869 -1.16898190025717 0.244240919981024 KANK2 other 0.294824158206486 1 1 3.51142843233812 -1.16898190025717 4.5338046413554e-20 113.97990954696 27.2646003486122 4.18050908832638 4.89322040651359e-05 -216.298238393151 51.9422391447441 -4.16420704911096 5.21756774772273e-05 GTF2E2 other 6.40807948009173e-16 0.75065147186487 0.463485836904967 4.18050908832638 -4.16420704911096 0.00749427450998879 39.2385673392445 15.0509084544074 2.60705640846245 0.0100482585687654 -58.9190183620752 61.5387199001141 -0.957430028731649 0.339880652379407 RAD54B other 1 1 1 2.60705640846245 -0.957430028731649 0.00951729128723804 22.3405494383887 10.2192730588684 2.18611923858921 0.0303366831751275 -29.8403096700419 29.0923382011409 -1.02571025621006 0.306657744047751 ZNF165 other 1 1 1 2.18611923858921 -1.02571025621006 0.00617992932725464 21.9124275362319 6.80776620147117 3.21873972867878 0.0015682845971648 20.2121014492754 27.0663299681084 0.746761806018429 0.456338577877026 RAMP2-AS1 other 1 1 1 3.21873972867878 0.746761806018429 0.0473627638522535 24.2626746251167 11.6797140780817 2.07733463875184 0.0394202663030729 -30.1134536865812 51.2181214715615 -0.587945297902061 0.557424646721286 FITM2 other 1 1 1 2.07733463875184 -0.587945297902061 1.92076898908829e-05 86.2351747303821 18.7086621961189 4.60937152140529 8.53776225924528e-06 5.73534975868445 34.3575248146859 0.166931401188508 0.867647360311061 BLM ts 0.153930426785535 1 0.0872217792404498 4.60937152140529 0.166931401188508 1.01245250661715e-13 368.839842892878 53.5243079274499 6.89107168639763 1.33290888288346e-10 -13.5136426471232 124.504617041311 -0.10853928929109 0.913709207809588 DDI2 other 1.32074429488207e-09 1 1.72998243909444e-06 6.89107168639763 -0.10853928929109 0.0582470180684499 150.272773558488 73.0572380905923 2.05691834903678 0.0413382642439424 -181.329097543384 335.271459657214 -0.540842628623318 0.589377726118899 SVIL other 1 1 1 2.05691834903678 -0.540842628623318 1.5981792664811e-14 549.13851016361 70.3951117493586 7.80080458027844 8.91578032957115e-13 -329.09655905572 229.338705124483 -1.43498045337392 0.153333671120697 TRIM33 other 2.12366060930008e-10 1 1.21192202019861e-08 7.80080458027844 -1.43498045337392 2.99140546161942e-06 1319.32772367002 300.301696633397 4.39334089171208 2.09119568168962e-05 -972.826174042867 720.306651681238 -1.35057224832262 0.178853067658848 LRP10 other 0.0260222361106273 1 0.205878214862344 4.39334089171208 -1.35057224832262 1.14688142756335e-10 265.50137481731 41.5048502179884 6.39687586927468 1.78166350740125e-09 -221.963249440577 136.812349760938 -1.62239191000248 0.106751708663503 ZNF655 other 1.35473891097902e-06 1 2.23046454491562e-05 6.39687586927468 -1.62239191000248 0.203145098484605 124.797657291968 71.6416414252728 1.74197093770026 0.0834972146993174 -9.05133082052798 218.708152823853 -0.0413854294120344 0.967041890006489 MRPL21 essential 1 1 1 1.74197093770026 -0.0413854294120344 0.541249741581948 114.790938162154 106.330549198883 1.07956686979437 0.282349436591506 35.017555604664 459.381917940884 0.0762275445268402 0.939356163665631 LYPD2 other 1 1 1 1.07956686979437 0.0762275445268402 0.0772692978646767 85.6319280219633 53.5373486862954 1.59948017829063 0.112321886318257 -55.1859795047432 83.7609091593722 -0.658851247659462 0.511243114750651 UAP1L1 other 1 1 1 1.59948017829063 -0.658851247659462 3.35654813767915e-09 29.6091512295705 4.76172208914151 6.21816029479971 4.40933556209245e-09 11.7533027565377 14.4221168192077 0.81494990672135 0.416343391501253 ZNF98 other 3.68515420035794e-05 1 5.44156101717829e-05 6.21816029479971 0.81494990672135 0.00390620528078492 24.0627620694297 7.50817789809529 3.20487372515961 0.00164281329174376 4.71399049561535 12.3041804686325 0.383121046349484 0.702158342633487 FBXL22 other 1 1 1 3.20487372515961 0.383121046349484 5.09825000977118e-14 80.2608345083207 9.28581627598813 8.64337955036483 1.12556371945605e-14 34.7979669202388 31.1593492251672 1.11677450863232 0.26600372637222 ZNF786 other 6.70776753785594e-10 1 1.56430845730002e-10 8.64337955036483 1.11677450863232 1.45738407313314e-06 140.705173576003 26.640211758604 5.28168375127721 7.49033012579553e-07 -0.954583754634275 98.1807198247846 -0.00972272108350646 0.992261883571381 ZNF517 other 0.0131004254333938 1 0.00824385733645056 5.28168375127721 -0.00972272108350646 0.0143424552297384 26.9720496894411 16.0240445150324 1.68322358716229 0.0944544035727027 -49.778007821486 41.2466349585809 -1.20683803348982 0.2294329954824 ZNF675 other 1 1 1 1.68322358716229 -1.20683803348982 1.38231052101437e-09 78.8722205464104 25.5916250691576 3.08195436332277 0.00243699380223004 -139.204279065759 40.1731396110876 -3.46510828910517 0.000686794884468583 SLC22A5 other 1.5487407077445e-05 1 1 3.08195436332277 -3.46510828910517 0.36464521518141 36.760867635309 26.4821534106158 1.38813740202007 0.167061828177072 29.7577900748675 54.3849631900511 0.547169444077352 0.58503925458638 DACT3 other 1 1 1 1.38813740202007 0.547169444077352 0.0823925343390452 52.7889270410625 35.9991191764943 1.46639496322819 0.144648047839851 -51.2395924969492 64.0195256834051 -0.800374447482532 0.424768175388492 ADARB1 other 1 1 1 1.46639496322819 -0.800374447482532 7.27907671940067e-09 43.4738092850698 7.11920590529484 6.10655315542097 7.95221903513105e-09 10.4422507436746 15.6926954349702 0.665421105440218 0.506776573401472 ZNF860 other 7.8228237503399e-05 1 9.71840688283366e-05 6.10655315542097 0.665421105440218 1.18586660363374e-10 674.632461645427 111.658693555296 6.04191612999063 1.13854623162622e-08 44.1349705879665 211.181383083925 0.208990820798001 0.834737072699131 HTT other 1.39991552558963e-06 1 0.000138265054368688 6.04191612999063 0.208990820798001 0.242569098722223 55.4173043372828 32.7781578833806 1.69067781461205 0.0928826870791349 61.4576123052466 63.137908244611 0.973386892501181 0.33185837598685 C5AR1 other 1 1 1 1.69067781461205 0.973386892501181 0.216936515286818 -8.0553141811792 4.87958184096966 -1.65082059154038 0.100839905635617 -1.36240657608106 7.89829320992382 -0.172493795794928 0.863278802579927 DIO3 other 1 1 1 -1.65082059154038 -0.172493795794928 0.194365890896956 5.33590308370045 3.08280932316312 1.73085732017494 0.0855473833030842 1.68718602674085 8.74562892130072 0.192917632559457 0.847286185594808 HIST1H3D other 1 1 1 1.73085732017494 0.192917632559457 0.803005498829702 -15.7893196781277 24.6443021845524 -0.64068844635515 0.522659161852172 -21.2224305047555 39.1634377830548 -0.541893962994689 0.588659798899246 DCHS2 other 1 1 1 -0.64068844635515 -0.541893962994689 0.783287697316606 7.94955953448728 13.7557375799645 0.577908635453031 0.564186613254216 -20.2506094315817 53.7539699739441 -0.376727699208034 0.706904839195113 VEPH1 other 1 1 1 0.577908635453031 -0.376727699208034 1.29432044532864e-11 94.132028706718 13.1904513360448 7.13637663401927 3.395471426908e-11 -119.230220972674 74.0453038803709 -1.61023339394088 0.109368537717959 SHPK other 1.58476595326038e-07 1 4.47998500066241e-07 7.13637663401927 -1.61023339394088 1.46273351958038e-11 89.8870228892036 15.0466165351107 5.97390268300223 1.5290465499491e-08 -135.103459502843 47.4015600982749 -2.85019014612053 0.00496410143298667 IPP other 1.78775290763114e-07 1 0.000184555918578857 5.97390268300223 -2.85019014612053 0.0979314360700268 31.9219702956254 24.6437200075008 1.29533894582106 0.197141721363042 -34.6630498652562 50.5020840172606 -0.686368702198688 0.49351276020676 MAP3K5 other 1 1 1 1.29533894582106 -0.686368702198688 0.094202623779043 55.5585607567854 73.9844082756722 0.75094958588801 0.453807076579105 -246.938830286422 156.465962051125 -1.57822715592121 0.116526164808438 OGDHL other 1 1 1 0.75094958588801 -1.57822715592121 0.911595455692443 -3.17079148252311 7.77055740960929 -0.408051998766784 0.683791439270171 -7.46576354140035 23.0555070984678 -0.323816930571721 0.74650759922981 CYP2F1 other 1 1 1 -0.408051998766784 -0.323816930571721 2.14688942843998e-07 868.870046903924 165.173872877619 5.26033586163891 4.98765161534811e-07 -1020.5100029228 671.283426681276 -1.52023714925906 0.130599396222397 GSTK1 other 0.0020781889667299 1 0.00556073278595161 5.26033586163891 -1.52023714925906 0.056929303757114 795.126221335993 343.472877754666 2.31496072276173 0.0219356769843337 254.880014501949 561.364857424849 0.454036285190991 0.650441951461769 HNRNPAB other 1 1 1 2.31496072276173 0.454036285190991 0.319461159753667 76.1762031142704 83.1317239142386 0.916331329696184 0.36139422482129 -192.835145969822 285.299460648243 -0.675904348124852 0.500446687948353 STMN3 other 1 1 1 0.916331329696184 -0.675904348124852 0.0112635449449936 12.5839237680994 37.214201480746 0.338148429024068 0.735743828521304 -140.344565901677 69.8618252658102 -2.00888776334849 0.0464182527748231 PDGFA other 1 1 1 0.338148429024068 -2.00888776334849 0.0361451611725428 125.528273838759 70.311967823545 1.78530451819788 0.0761425413514679 -156.316804515955 154.210601107891 -1.01365796769439 0.312305593213265 COL13A1 other 1 1 1 1.78530451819788 -1.01365796769439 2.39810912720376e-06 24.6546363405044 6.05046309564393 4.07483459543034 7.35206088986504e-05 -28.7784554013347 18.9003858202864 -1.52263851515908 0.129899948039302 ZNF695 other 0.0211033603193931 1 0.682271250579476 4.07483459543034 -1.52263851515908 0.00221714878116375 69.5235212385868 21.286466159887 3.26609032783466 0.00135322489032671 -10.912184241867 50.5611628075199 -0.215821465250085 0.829422081494544 PCDHB11 other 1 1 1 3.26609032783466 -0.215821465250085 8.35499475778248e-19 189.796236384009 24.3642447328718 7.78994951269469 1.02620751812638e-12 -73.5544170641817 48.3762562718282 -1.52046525987617 0.13049921883923 ZNF628 other 1.17178801477899e-14 1 1.393384568112e-08 7.78994951269469 -1.52046525987617 0.0787121659597522 87.1109309114503 40.5678678209872 2.14728886654439 0.0333454784239894 -11.9909179370738 180.946183667623 -0.0662678686780141 0.947251077211174 SLC2A10 other 1 1 1 2.14728886654439 -0.0662678686780141 0.000374281517914312 10.0340813632546 4.35245375054957 2.30538494797046 0.0224711808259681 -19.5467836895293 10.8338657885161 -1.8042298170473 0.0731368755026241 ZNF665 other 1 1 1 2.30538494797046 -1.8042298170473 5.66973781013336e-18 155.944089286408 30.7370133145472 5.07349519260554 1.11748000132241e-06 -242.647859997671 64.2235686022826 -3.77817466824861 0.000225796330175061 RPF2 essential 7.90191358598286e-14 1 0.0121805320144142 5.07349519260554 -3.77817466824861 0.166486181067606 -41.5054566341174 62.7928476653662 -0.660990195178073 0.509619212529879 -159.170591614014 85.3224211493148 -1.86551892773254 0.0640360806936157 SLC28A3 other 1 1 1 -0.660990195178073 -1.86551892773254 4.2206506494476e-11 320.807339946875 62.3911484707778 5.14187265036693 9.75419559021891e-07 -266.409096330025 140.301968987077 -1.89882649725724 0.0598034539682214 MIB2 other 5.07195588544118e-07 1 0.0106662128779044 5.14187265036693 -1.89882649725724 0.28621430220777 57.8446705945384 44.4805106670941 1.30044978636747 0.195415133254924 -14.9125104471496 66.6260484996655 -0.223824026532573 0.82319478654796 MYO5A other 1 1 1 1.30044978636747 -0.223824026532573 9.37298949200855e-06 34.4935361544429 16.7163201654557 2.06346467482263 0.0407470511948599 -71.2192536412996 26.2408917751699 -2.71405614761499 0.00740450267015706 C5orf56 other 0.0776645909307828 1 1 2.06346467482263 -2.71405614761499 6.28174068040682e-13 435.309589785384 82.8602043061091 5.25354231782035 4.79282404794492e-07 -466.7974463461 161.198208010466 -2.89579798750487 0.00432156677574154 ATG7 other 8.02492371921971e-09 1 0.00534879163750653 5.25354231782035 -2.89579798750487 0.000136173019101573 639.64286510032 226.814987048959 2.82010846559381 0.00542444914265435 -436.333311052438 339.02521299896 -1.28702318978788 0.199992604444724 SIPA1L1 other 0.980718083569528 1 1 2.82010846559381 -1.28702318978788 0.000515083947146478 148.443905541253 41.0125164256861 3.61947811249842 0.000407956049787032 -106.651166176291 150.897713637834 -0.706777880228599 0.480846628507448 TTC30A other 1 1 1 3.61947811249842 -0.706777880228599 0.0263243615591816 50.2333573969989 19.0967685795646 2.63046374509421 0.0095989208801659 1.24582323518798 58.1038050060383 0.0214413365021191 0.982927788085347 SSPO other 1 1 1 2.63046374509421 0.0214413365021191 6.30386598834466e-10 187.470374322896 38.2009757719327 4.90747606663586 2.69093091007597e-06 -113.568974847889 82.0078697269222 -1.3848545904931 0.168450932713704 RAB40C other 7.18892877310825e-06 1 0.0285992137122874 4.90747606663586 -1.3848545904931 1.89795103663571e-21 197.753049914195 22.9264134551357 8.62555542327516 7.32683288992735e-15 28.4625469542618 46.7158046100663 0.609270185793368 0.543243162347748 PIGN other 2.70287207127292e-17 1 1.02084762655358e-10 8.62555542327516 0.609270185793368 3.72206838054858e-06 19.4119746649404 3.73441024956837 5.19813661800657 6.26619604019827e-07 17.6851313993771 12.5791940640359 1.4059033757925 0.16175425667024 ZNF624 other 0.0320842294403288 1 0.00693542577729145 5.19813661800657 1.4059033757925 0.0248132614573361 31.9838471023428 22.4807395683791 1.42272219314931 0.156813298331033 -123.579860254829 67.8400093145939 -1.82163684090539 0.0704256631729443 HHLA3 other 1 1 1 1.42272219314931 -1.82163684090539 0.0605550711944261 172.248441195442 72.0443535937614 2.39086663427788 0.0180921025038226 202.290910992696 152.442072735741 1.32700183986193 0.186593917022974 HOXA4 other 1 1 1 2.39086663427788 1.32700183986193 6.96240809788516e-21 180.068323658193 20.7188760894529 8.69102758666811 5.35614684561522e-15 -115.149248112852 50.6381830692915 -2.27396089538375 0.0243681632803798 TOPORS other 9.88661949899692e-17 1 7.46753993215674e-11 8.69102758666811 -2.27396089538375 0.309025241391903 0.380178697390084 4.31789863752424 0.0880471565696752 0.929956633840802 -13.1697625205737 10.4606017975804 -1.25898708080256 0.209990757943663 BCO2 other 1 1 1 0.0880471565696752 -1.25898708080256 0.028480620350921 28.0208171498325 11.7751097544054 2.37966505062505 0.018638634382618 -76.294405894167 59.7428447706474 -1.27704675241129 0.203641083167652 KCNMB2 other 1 1 1 2.37966505062505 -1.27704675241129 0.00162765049279229 123.811944634313 56.0572512161736 2.20866956456457 0.028724831487377 -443.865857826384 216.373370455029 -2.05138856455831 0.0419803821796653 ENTPD6 other 1 1 1 2.20866956456457 -2.05138856455831 0.921215259071344 10.0548101627177 25.344932221333 0.39671876314013 0.692117040492325 2.98639261585307 85.2854075030499 0.0350164547873712 0.972111385286775 DMBX1 other 1 1 1 0.39671876314013 0.0350164547873712 0.00997189250331545 80.7056521236675 35.9954131517324 2.24210934275061 0.0263552753679898 -24.5523762100281 72.3994504634502 -0.339123792416395 0.734969645564913 ENPP1 other 1 1 1 2.24210934275061 -0.339123792416395 0.130315954717218 0.341730977740898 6.98888626630186 0.0488963426674452 0.961073115497858 -26.6616793538004 15.4600871490529 -1.72454909838161 0.0868641285975364 CCDC154 other 1 1 1 0.0488963426674452 -1.72454909838161 4.23193810925265e-07 128.621443419157 62.8939190856361 2.04505372362035 0.0425518691197836 -310.110956523652 100.289501464391 -3.09215772334616 0.00235953606351106 FAR1 other 0.00399114083083618 1 1 2.04505372362035 -3.09215772334616 1.30175314013525e-05 106.416535388236 22.6063008356147 4.70738384674524 5.74631005265514e-06 -70.4242982139808 95.0896276221998 -0.74060967505082 0.460111470638229 C5orf42 other 0.106327196486247 1 0.0595949815560865 4.70738384674524 -0.74060967505082 2.85650084189756e-06 41.2116636087734 12.5859183631476 3.27442642004129 0.00130427104375267 -38.4013694115563 24.4077081228908 -1.57332958990695 0.11766845654689 ZNF841 other 0.0249144003430305 1 1 3.27442642004129 -1.57332958990695 0.779677476261079 19.7903408099184 140.393929175137 0.140962938541527 0.888084642606206 -400.005163734272 645.011202324674 -0.620152273778533 0.536080108137916 MFAP5 other 1 1 1 0.140962938541527 -0.620152273778533 0.00282587262586999 46.8642056805352 15.7042303817895 2.98417716380923 0.00334138685527759 100.252723008773 37.5725214373873 2.66824581298966 0.00849923039808198 MYH6 other 1 1 1 2.98417716380923 2.66824581298966 2.91272274287955e-05 26.872680141073 9.89453964194286 2.71591009925919 0.0073551656173982 -32.1523929450382 19.188352301573 -1.67562031589354 0.0958157823983046 ZNF615 other 0.228823498680618 1 1 2.71591009925919 -1.67562031589354 0.969385171993097 10.4817141704372 47.06254966323 0.222718791171371 0.824057360620268 30.3547191561716 177.021836207526 0.171474433925689 0.864081840190059 MPEG1 other 1 1 1 0.222718791171371 0.171474433925689 0.79499204118521 -5.38624507612051 29.4822706419365 -0.182694377293279 0.855278115588912 37.6741545122254 83.1855267993342 0.452893140931902 0.651263104403132 SERPINB2 other 1 1 1 -0.182694377293279 0.452893140931902 0.634640305496346 5.44805967780348 48.9367710896818 0.111328548175345 0.911501730470727 -124.036319868793 140.762366805797 -0.881175293393015 0.379605093154379 DPP4 other 1 1 1 0.111328548175345 -0.881175293393015 0.85177208177879 2.71522140080007 5.63985582987135 0.481434540652435 0.630909286207632 0.303809820621146 13.223437151982 0.0229751022468171 0.9817006680731 PDCD1LG2 other 1 1 1 0.481434540652435 0.0229751022468171 2.78407377255507e-13 26.9569246398324 4.4388231409055 6.0729891198894 9.86361372729927e-09 -47.5345876692932 18.1641060273311 -2.61695167368926 0.00978020282023746 ZNF433 other 3.59117675921879e-09 1 0.000120099360743596 6.0729891198894 -2.61695167368926 0.00423372865091774 27.9203261895134 14.835100230506 1.88204499839507 0.061741495406414 -56.6030597115514 35.14797809724 -1.61042150290847 0.109380614690029 DNAH10 other 1 1 1 1.88204499839507 -1.61042150290847 3.42339222312145e-09 3161.46852779036 540.754894040133 5.84639836390594 2.90396088558544e-08 523.059675357533 735.004999637546 0.711640976068829 0.477763731037186 SPTAN1 other 3.75614594720886e-05 1 0.000346328220004604 5.84639836390594 0.711640976068829 5.77363414231773e-06 100.816607156849 23.095390657241 4.36522631953143 2.3273187060646e-05 -31.9650496412621 40.502571427462 -0.789210376395726 0.431210343794014 NMB other 0.0487756612343002 1 0.227891047697846 4.36522631953143 -0.789210376395726 0.00456363649423166 98.8276721539528 114.62372758648 0.86219209787424 0.389931170031472 -380.646633102581 183.232576286788 -2.07739606578913 0.0394361734348835 PARVA other 1 1 1 0.86219209787424 -2.07739606578913 0.000618986579518956 322.165100152576 88.5048347400128 3.64008476032922 0.000376013803735284 176.887724463049 229.965464884696 0.769192559203354 0.443004824779248 KLHL14 other 1 1 1 3.64008476032922 0.769192559203354 0.000370497597653563 -5.67499014846094 76.3223869017868 -0.0743555119124305 0.94082400318711 -444.724315463769 133.219964317596 -3.33827078953082 0.00105719409204774 FAM114A1 other 1 1 1 -0.0743555119124305 -3.33827078953082 9.15493571630739e-06 112.924329099016 36.7636480583364 3.07163013093335 0.00252041311733679 -269.650837048877 106.250485654711 -2.53787863074036 0.0121528373080475 RPE essential 0.0759218818953372 1 1 3.07163013093335 -2.53787863074036 0.000400371757404646 24.4231773011677 8.122076469044 3.0070114944439 0.00307903037862278 -9.905962458594 16.1636053885224 -0.612855994716877 0.540869717093265 ZNF460 other 1 1 1 3.0070114944439 -0.612855994716877 9.26482415649124e-08 237.552945891783 71.3490918566057 3.32944596364599 0.00108446518279695 -263.796748496994 110.422540757676 -2.38897553603571 0.0180824175752119 PHF2 other 0.000924444154334696 1 1 3.32944596364599 -2.38897553603571 0.0142009066779813 3281.76388566702 1382.58517131341 2.3736431966426 0.0188631445612334 -1857.22097166829 3203.75633228005 -0.579701069321505 0.562974467642061 PSAP other 1 1 1 2.3736431966426 -0.579701069321505 0.0010668895658386 64.8478457395196 28.6574372645305 2.26286269567384 0.0250329679161238 -58.7110976481335 49.2078179229231 -1.19312540418061 0.234643368317701 CFAP43 other 1 1 1 2.26286269567384 -1.19312540418061 9.37212305238777e-09 25.6120692887666 7.04591535761787 3.6350236965415 0.000378348981912503 -66.0846833384487 20.2878459285772 -3.25735337162446 0.00138345223259271 LHFPL5 other 0.000100122390568659 1 1 3.6350236965415 -3.25735337162446 0.0129511374122783 1700.28467093519 2463.06891804576 0.690311447835665 0.491086819966588 -15723.8951315768 6611.56572896247 -2.3782407641653 0.0186808807186601 RPL37A essential 1 1 1 0.690311447835665 -2.3782407641653 0.441569519688253 6.01153375597825 14.45150523359 0.415979765346899 0.678057255874459 -42.0125058391725 41.179598689357 -1.0202262085189 0.309368497285501 HOXC6 other 1 1 1 0.415979765346899 -1.0202262085189 0.0525266550500806 19.1676439208105 7.86613589404513 2.43672931398514 0.0159913262681616 3.3194754744166 33.3611323963172 0.0995012829595388 0.920873124549432 TXNRD3 other 1 1 1 2.43672931398514 0.0995012829595388 0.955504209142747 8.8082866161021 39.9475865267683 0.220496089549735 0.825808350177536 -4.87468789748908 59.6207696391243 -0.0817615728041561 0.934953928577484 CFD other 1 1 1 0.220496089549735 -0.0817615728041561 0.0700502765842476 21.5249938840415 9.24505239940505 2.32827170189178 0.0215575966149642 14.7261409660496 14.4641827285412 1.01811082191264 0.310656671850419 STPG3 other 1 1 1 2.32827170189178 1.01811082191264 6.10450046159806e-07 344.469911156464 76.8193767070701 4.48415394555994 1.41156879518652e-05 -104.037634458934 137.676227845733 -0.755668833224495 0.45098727049763 MCMBP essential 0.00567047047877844 1 0.141086301078893 4.48415394555994 -0.755668833224495 1.75749474922118e-11 308.658020359327 62.9113643722068 4.90623631261901 2.59369518109922e-06 -324.025190842849 135.267402769902 -2.39544180052038 0.0179520904955061 EME2 other 2.1422103498257e-07 1 0.0275891356413524 4.90623631261901 -2.39544180052038 0.0175373659794865 14.8197885461557 5.38632521936497 2.75137277134241 0.00666132119115038 3.49663905043971 8.64280408473435 0.40457229114053 0.686364430276649 KLHDC1 other 1 1 1 2.75137277134241 0.40457229114053 0.0233492546803197 6.13718173394565 26.8740353729987 0.228368447416419 0.819672930437241 -220.007971758924 85.9023298644374 -2.56114091557375 0.011426609480365 TAF13 other 1 1 1 0.228368447416419 -2.56114091557375 7.12338491983118e-20 79.4509509009326 8.28805638224525 9.58619816717621 2.02273040859302e-17 -5.40336088264397 30.6763273451735 -0.176141062189249 0.860410117660744 ZNF780A other 1.00560824913257e-15 1 2.8658044428946e-13 9.58619816717621 -0.176141062189249 1.02881502102572e-10 182.045263620114 40.186895068645 4.52996588338447 1.32759276588455e-05 -228.57235304293 90.4793703125067 -2.52623722129657 0.0127387502136165 ATAD3A other 1.21770545888604e-06 1 0.133184106273538 4.52996588338447 -2.52623722129657 2.42823215010083e-07 106.114613668932 22.1528837140925 4.79010385457975 3.90612168507823e-06 -95.3973183331021 62.935121294741 -1.51580415466799 0.131632184185545 FAM118B other 0.00233668779804203 1 0.0410377144234319 4.79010385457975 -1.51580415466799 3.28946852669064e-15 40.3035270178612 5.50462895145291 7.32175181530143 1.4194640205263e-11 -37.4208086914098 20.0965827536176 -1.86204834673564 0.0645658042534257 ZNF461 other 4.42400622154624e-11 1 1.88731936169177e-07 7.32175181530143 -1.86204834673564 0.0302093983794301 45.7567385444744 40.5494847205158 1.12841726250899 0.260865114839648 -88.5936236522911 60.6479756900241 -1.46078451332158 0.146072958071665 CCDC180 other 1 1 1 1.12841726250899 -1.46078451332158 3.20605285057969e-05 110.475709359308 26.5171127357265 4.1662043096594 5.19318569987163e-05 -115.605431775557 131.970517985922 -0.875994377682821 0.382424473143432 SLC9A8 other 0.250360667101768 1 0.490548321209874 4.1662043096594 -0.875994377682821 5.47950225452611e-07 67.1771810599984 63.039488125214 1.06563652494395 0.28847617766737 -284.08703405254 91.4265986525549 -3.107268981231 0.0022993518268537 OCLN other 0.00511127970302195 1 1 1.06563652494395 -3.107268981231 0.000486317606290705 5.26137184115523 1.42307797258351 3.69717748606813 0.000304508054919455 -0.849588006724168 5.32706805453626 -0.159485104756772 0.873499820204547 HIST4H4 other 1 1 1 3.69717748606813 -0.159485104756772 7.41341536249214e-27 54.774841383105 4.78854891300543 11.4387139774932 2.02089884307795e-22 -51.862191960354 21.0559533206012 -2.46306548892336 0.0148553108225539 ZNF181 other 1.07131265403374e-22 1 2.90948806437932e-18 11.4387139774932 -2.46306548892336 7.709560185237e-23 76.1479626643513 7.83869067690401 9.71437269347984 1.38521378743437e-17 -84.4129300008269 34.2999899376319 -2.46101908934422 0.0149960321076415 ZNF44 other 1.10346934931297e-18 1 1.96381758644571e-13 9.71437269347984 -2.46101908934422 1.38639417149634e-05 1410.02866541354 291.293413910664 4.84057859902722 4.29509982383926e-06 373.238878446116 1216.01190704128 0.306936861625194 0.759477035661016 GPAA1 other 0.112820645334732 1 0.0450427118526023 4.84057859902722 0.306936861625194 0.0230323447995182 56.269695258901 20.6073841115192 2.73055983012649 0.0070458008349171 53.3479730973625 27.7349421295933 1.92349321834135 0.0562276880264715 ADAMTSL2 other 1 1 1 2.73055983012649 1.92349321834135 2.02481259217315e-08 0.52235998176346 14.1456704336651 0.0369271986232834 0.970591505868478 -87.5513839153314 19.6926902636513 -4.44588234228887 1.67965684701456e-05 SGTB other 0.000211916885896842 0.243348683995469 1 0.0369271986232834 -4.44588234228887 2.5171597686808e-17 22.6292024639834 2.76222068315299 8.19239483724117 1.03990288906445e-13 -23.3216682646213 11.5718940095342 -2.01537174860108 0.0456517751985514 ZNF790 other 3.48601456364604e-13 1 1.4295545015969e-09 8.19239483724117 -2.01537174860108 0.00447767121513489 59.4572848476238 17.770664263778 3.3458110493267 0.00103077144643006 66.8531172557138 55.421087973623 1.20627580042333 0.229561048035562 FAM49A other 1 1 1 3.3458110493267 1.20627580042333 0.00427929118153423 712.089509619082 240.227638933437 2.96422806626505 0.00356374731375884 -947.216635243682 1016.86468377274 -0.931507063190896 0.353183549160939 MYO1C other 1 1 1 2.96422806626505 -0.931507063190896 2.9654144056115e-12 53.207234068804 8.7702576394494 6.06678118889839 9.60502309917887e-09 -38.800811210956 19.1634148994725 -2.02473366122361 0.0446114725782998 NKIRAS1 other 3.71151267006336e-08 1 0.000116998786371098 6.06678118889839 -2.02473366122361 0.180352333842946 122.929712204832 72.7129069873542 1.69061748866966 0.0929594930893 38.3829979162643 152.550572461954 0.251608350573952 0.80168366015914 UGT2B17 other 1 1 1 1.69061748866966 0.251608350573952 2.19143085098963e-08 9.58867590588055 49.3441934606216 0.19432227448469 0.846184732184752 -393.549295997219 92.7824069025274 -4.24163706391732 3.85357420399251e-05 KIF13B other 0.000228763466534807 0.555338578537361 1 0.19432227448469 -4.24163706391732 0.0657592099009349 8.09491189831777 5.43194156333059 1.49024281722103 0.138205710582399 -9.70758784220741 10.5185026772366 -0.92290586788706 0.357499963509382 NRAP other 1 1 1 1.49024281722103 -0.92290586788706 2.45495886475541e-14 546.812500000001 117.144418464285 4.66784937061867 6.51382762100292e-06 -399.198863636364 175.76433400081 -2.27121654632461 0.0245015193277066 ADH5 other 3.25061103282263e-10 1 0.0672161872211292 4.66784937061867 -2.27121654632461 0.511233738969573 81.934600650524 117.200768982518 0.699096101176139 0.485596632907551 -177.946353451391 335.546685755688 -0.530317720321499 0.596691838812783 HIST1H2BK other 1 1 1 0.699096101176139 -0.530317720321499 4.53902310749353e-07 88.3624138300208 21.0115006877585 4.20543088012278 4.4200782029016e-05 -210.984427254301 99.6069291547413 -2.11817018198134 0.0357764978743529 TEAD4 other 0.00426804342797617 1 0.420393637877971 4.20543088012278 -2.11817018198134 1.27151299794902e-14 643.673478112174 81.1173126960504 7.93509371450756 6.09647405907302e-13 202.79872748518 143.162404416624 1.41656413435894 0.158831661553444 SPG7 other 1.69251095156994e-10 1 8.30827484770472e-09 7.93509371450756 1.41656413435894 1.16060148027961e-05 95.5951265803412 22.3271934129295 4.28155589519741 3.25197202134975e-05 -4.99434235828787 55.323974663879 -0.0902744675998246 0.928186415709578 ZNF677 other 0.0952828667873412 1 0.313945378941105 4.28155589519741 -0.0902744675998246 0.534604890456662 97.8349018485445 164.58734240949 0.594425430390225 0.553083235119747 -152.898489848145 252.873024368787 -0.604645316477727 0.546287537972268 ERO1A other 1 1 1 0.594425430390225 -0.604645316477727 1.51904569115298e-15 33.1174145488636 5.24524898072405 6.31379266657654 2.92139295898109e-09 -68.5167383158364 20.4429725113996 -3.35160350470703 0.00101682145889493 ZNF823 other 2.05618024754467e-11 1 3.62837005505451e-05 6.31379266657654 -3.35160350470703 5.94778360573828e-10 26.1296954323237 4.206294425652 6.21204623075654 4.6607343947096e-09 -3.079559371739 11.9735395482037 -0.257197076882834 0.797369966063362 ZNF311 other 6.79355843447426e-06 1 5.74761765555588e-05 6.21204623075654 -0.257197076882834 6.68632246155872e-07 34.6047041881676 9.51795528143364 3.63572880570996 0.000376685717202891 -45.5283311332452 23.6915211533562 -1.92171413724507 0.0564765435620106 ZNF347 other 0.00619019733491106 1 1 3.63572880570996 -1.92171413724507 2.98486241802369e-07 153.084379735874 29.6780857423193 5.15816218960458 7.56996872743422e-07 72.9402172843394 54.9670119090121 1.32698167048045 0.186478879254979 PLCG2 other 0.00284636480182739 1 0.00832696560017764 5.15816218960458 1.32698167048045 0.000593093561237409 90.9178830398342 35.7010292527443 2.54664599152545 0.0119269416454034 -73.0551908304521 53.3034345131458 -1.37055316411994 0.172646947478832 FCHSD1 other 1 1 1 2.54664599152545 -1.37055316411994 3.16864957853882e-11 66.3423978296534 12.7236917456939 5.21408402180963 5.8245765787467e-07 -41.2556175741857 25.432826085347 -1.62214051382811 0.106805568229313 ZNF71 other 3.8242431763385e-07 1 0.00646003788348796 5.21408402180963 -1.62214051382811 0.0172788787811667 -2745.46482378442 1502.23752912852 -1.82758370134523 0.0695227900621285 -5965.32266792736 2080.96591460854 -2.86661238708926 0.00472230557257198 RPL12 essential 1 1 1 -1.82758370134523 -2.86661238708926 5.39771687361854e-29 453.296815085737 34.5805410975466 13.1084361522005 1.52672750568313e-26 70.3966618158884 121.948652886274 0.577264776196734 0.564637701136367 ZNF121 other 7.81535426131228e-25 1 2.20932737347406e-22 13.1084361522005 0.577264776196734 2.73773105860721e-07 162.085988947001 32.3715656369763 5.00704818434419 1.47884105640009e-06 -23.0088244012958 46.9259976545487 -0.490321475329688 0.624595352519645 VPS13A other 0.00262219880793398 1 0.0159921871839106 5.00704818434419 -0.490321475329688 4.80641157263439e-10 77.7230124486475 64.9918743960229 1.19588815018703 0.233836492548399 -525.243557188765 121.849851784504 -4.31058018944231 3.11696747856411e-05 MBP other 5.5148766384407e-06 0.449840746506372 1 1.19588815018703 -4.31058018944231 0.453457575521677 9.84786449959408 8.2530520507859 1.19323911190604 0.23461079460308 20.9876494984982 22.931838826379 0.915218777586889 0.361507627611491 ELOVL2 other 1 1 1 1.19323911190604 0.915218777586889 8.61990853569779e-05 139.109844608161 35.8032659071463 3.88539539853526 0.000152866997393608 -40.3900577348261 62.5737428182995 -0.645479332315314 0.519602747371341 GOLGA6L9 other 0.637528435300209 1 1 3.88539539853526 -0.645479332315314 2.26789527589305e-10 17.5358216981696 2.44430536232417 7.17415342962537 2.98637876311968e-11 5.419343916187 9.64452012569692 0.561909130320301 0.575005568718026 LEKR1 other 2.64232478594299e-06 1 3.94381179457585e-07 7.17415342962537 0.561909130320301 0.000240872119763752 260.479025200919 94.8237212362189 2.74698168143001 0.00674183636210262 -780.388075979279 376.614322133741 -2.07211470758181 0.0399439964285098 C1orf122 other 1 1 1 2.74698168143001 -2.07211470758181 1.54224187986073e-05 45.6561654612023 19.6145222056203 2.32767155797046 0.0212573304393039 -99.4389992929859 45.2209462604611 -2.19895883470113 0.0294020057227937 SNHG12 other 0.12479821291833 1 1 2.32767155797046 -2.19895883470113 0.063471946979138 2.77690611618841 1.2300967879323 2.25746961005904 0.0254420746907387 -1.28249291664004 4.89508936380021 -0.261995812808696 0.793688962850736 KEL other 1 1 1 2.25746961005904 -0.261995812808696 1.07773260098514e-08 110.129428270782 32.8140586193831 3.35616601250689 0.000994074150579913 -140.174880159008 49.3272552408221 -2.84173282041858 0.00509088096330562 NOL8 essential 0.000114659971418809 1 1 3.35616601250689 -2.84173282041858 0.0578732629409296 19.3632308958848 15.7807850397744 1.22701315853939 0.221819956874163 -65.6668855055699 44.8261072785274 -1.46492500670531 0.145121286616966 IRAK4 other 1 1 1 1.22701315853939 -1.46492500670531 0.000426352411266035 64.2369882355921 19.2409168178237 3.33856171427791 0.00106227115414875 -36.014132485722 68.6412081325849 -0.524672182578115 0.600585640895912 CCDC151 other 1 1 1 3.33856171427791 -0.524672182578115 5.32125561747703e-16 249.088307844105 59.7120935452819 4.17148843818735 5.05431091573861e-05 -563.889340062996 121.20786089644 -4.65225057098221 7.05642803973363e-06 MRPL42 other 7.25287140662119e-12 0.102579294413608 0.478087269519716 4.17148843818735 -4.65225057098221 0.00105522793232721 40.7945769496532 18.5353746867369 2.20090381981023 0.0292027243916116 -37.9392718435036 31.7504319829918 -1.19492143803987 0.233919677413038 ENTPD7 other 1 1 1 2.20090381981023 -1.19492143803987 0.000451706454106411 77.094381657765 23.831321769792 3.23500233862344 0.00148700659770214 -132.142745433621 106.939560077753 -1.23567691261815 0.218448186018147 ZNF335 essential 1 1 1 3.23500233862344 -1.23567691261815 0.364720768920302 3.49378366383017 6.65217544701435 0.525209187830165 0.600223705508346 -21.4533048771801 23.0970261600265 -0.928834072773784 0.354487494304623 ZNF560 other 1 1 1 0.525209187830165 -0.928834072773784 1.42586306240152e-10 228.836926946757 41.8668418610971 5.46582729373227 1.94289532936774e-07 -81.4741843470252 79.9803331811059 -1.01867773121846 0.310041052296246 ZNF84 other 1.67624461615923e-06 1 0.00221975791380265 5.46582729373227 -1.01867773121846 2.63667638475297e-21 116.762113887146 21.7022082078045 5.38019508287441 2.82520102232452e-07 -156.799260526995 41.9394744687382 -3.73870351293681 0.000263128908680723 MAK16 essential 3.75225416314196e-17 1 0.00319530235624903 5.38019508287441 -3.73870351293681 6.75841590340132e-06 69.5447546216469 17.7806833624405 3.91125319561966 0.000136693324205163 -17.7310141455235 35.8703530306207 -0.494308325607709 0.62178379688696 ZNF667 other 0.0567098678454405 1 1 3.91125319561966 -0.494308325607709 0.117941618330952 -161.726876801604 91.0182131334962 -1.77686279738759 0.0775778907358803 -536.331432510339 321.646508599634 -1.66745609907407 0.0974692997071389 SIRPA other 1 1 1 -1.77686279738759 -1.66745609907407 5.34259021706609e-05 54.4507698023828 11.9386905691965 4.56086615921458 1.04210846168523e-05 54.9254348280426 23.423257836529 2.34491014065453 0.0203246002751708 DSCR8 other 0.405609449279657 1 0.105638534761032 4.56086615921458 2.34491014065453 0.000453895397152603 301.047238419392 83.6538159086272 3.59872690981865 0.000432093130321277 11.4942473599078 135.778241651623 0.0846545604073994 0.932647417861783 GRK6 other 1 1 1 3.59872690981865 0.0846545604073994 0.887022821757752 -0.357217030114231 19.2414907555693 -0.0185649352564244 0.985216421717148 -22.0244894427137 47.8274678264078 -0.46049875612593 0.645921772896906 PRIM1 essential 1 1 1 -0.0185649352564244 -0.46049875612593 1.96606651448727e-11 195.002581704518 53.045452040269 3.67614138826612 0.000324600547063558 -310.683795600222 94.2112362742123 -3.2977361075694 0.00120562314992809 MARCH5 other 2.39191652152521e-07 1 1 3.67614138826612 -3.2977361075694 0.0230542036869838 -25.7670786140711 91.0551411383456 -0.282983237321236 0.777567259536629 -505.953099369525 194.653172211949 -2.59925432306141 0.0102449420677517 NPIPB13 other 1 1 1 -0.282983237321236 -2.59925432306141 0.643801427714883 -6.38644896252885 6.8942637294153 -0.926342422219826 0.355698932807984 -0.973814404810724 25.2181726805481 -0.0386155815945328 0.969246252309968 AKR1B10 other 1 1 1 -0.926342422219826 -0.0386155815945328 0.0250168808416073 42.8890286864619 17.1948804604195 2.49429059918079 0.0136837684456114 -11.8240947108587 46.4450990998568 -0.25458218283563 0.799387675804368 SULT1C4 other 1 1 1 2.49429059918079 -0.25458218283563 1.07829681221641e-11 44.3206082570155 9.43964274638619 4.69515737488931 5.90546683366344e-06 -72.0428130662618 24.9727847455285 -2.88485300299405 0.00448543584433343 ZBTB14 other 1.32447197444541e-07 1 0.0611806363967533 4.69515737488931 -2.88485300299405 4.38390369892238e-10 264.118907628036 61.123567174531 4.3210650136612 2.82402540063947e-05 -547.802313733334 169.972196536016 -3.22289365494701 0.00155900768899994 CD2AP other 5.03885891154139e-06 1 0.274248279642934 4.3210650136612 -3.22289365494701 1.772612349866e-07 191.960987420581 33.0366662579384 5.81054353129395 3.49679974784401e-08 97.4967565369883 54.9761762937564 1.77343647939482 0.0781458510480171 SFI1 other 0.00172865156358932 1 0.000415769490018653 5.81054353129395 1.77343647939482 6.6961245731649e-05 93.3313100408757 24.1302652495357 3.86781119377341 0.000160906273428291 10.9098191989794 46.7955101999651 0.233138161168879 0.815959746835125 ZNF649 other 0.502142381741636 1 1 3.86781119377341 0.233138161168879 2.42269992287032e-07 88.0362470624298 15.4662103031129 5.69216668705913 6.71836392168466e-08 54.4927454786964 70.2363308484222 0.775848408088084 0.439102094952207 ZNF248 other 0.00233184867576268 1 0.000787660986178309 5.69216668705913 0.775848408088084 0.788433164384961 -4.45145179411554 17.091881283954 -0.260442470911297 0.79487267071201 -17.3983041921213 25.6665626485362 -0.677858754612533 0.498885075760465 CHSY3 other 1 1 1 -0.260442470911297 -0.677858754612533 0.0187825160515425 207.59516360318 86.1244709938044 2.4104085773498 0.0174523978717139 -28.9677170046756 134.200563981283 -0.215853914061909 0.829468098058224 TOR4A other 1 1 1 2.4104085773498 -0.215853914061909 0.0506693068125811 10.8041357864732 40.6042939662062 0.266083577157263 0.790521747615755 -135.930599637212 65.6703089753654 -2.06989432146882 0.0400899330825612 LPAR1 other 1 1 1 0.266083577157263 -2.06989432146882 0.334364710257458 -6.04415679794407 11.1278451895139 -0.543156082332961 0.587812778253697 -28.1827549802634 19.2150565346505 -1.46670164250839 0.144509644662212 MB other 1 1 1 -0.543156082332961 -1.46670164250839 1.51355974375576e-06 111.084782511843 25.96722279998 4.27788459965495 3.3228672531547e-05 -171.297375885472 93.9923966066095 -1.8224599230341 0.0703505537527934 HIBCH other 0.0135887393794392 1 0.320224717186518 4.27788459965495 -1.8224599230341 2.48047747619418e-10 171.124300965938 37.6235806178673 4.54832576154838 1.1385680270156e-05 -138.763712365136 74.8979845895289 -1.85270288814335 0.065971972937476 ZNF544 other 2.88529140030908e-06 1 0.115006756408846 4.54832576154838 -1.85270288814335 0.745987145065068 -2.9623963360201 18.8446732789567 -0.157200726813774 0.875295277609114 -19.7565497522415 27.3613199812816 -0.722061280879626 0.471366168334717 TMEM229B other 1 1 1 -0.157200726813774 -0.722061280879626 0.000200177137054871 65.3283591345233 20.1429361719442 3.2432391473054 0.00144917895087928 -81.714948529163 56.0375463338045 -1.45821781778958 0.146816916876156 SOWAHC other 1 1 1 3.2432391473054 -1.45821781778958 8.90225793955336e-12 619.445942647248 98.2495482160305 6.30482230091496 2.9778114710244e-09 -63.1807355659134 143.929539617872 -0.438969899672132 0.661306701523359 ZNF770 other 1.09675817815297e-07 1 3.69665516012969e-05 6.30482230091496 -0.438969899672132 5.24299010213695e-06 23.3766589524395 5.73687124172578 4.0748097643215 8.09305446039331e-05 -1.71444764558635 10.4821246719895 -0.163559173281703 0.870340244752539 ZNF876P other 0.044486771016632 1 0.747672516048383 4.0748097643215 -0.163559173281703 0.00508574467936521 3.76591937335405 3.10264644670489 1.21377650919704 0.226715692429106 -13.8765953136606 6.48969670118961 -2.13825020684201 0.0340948431956603 NPIPB6 other 1 1 1 1.21377650919704 -2.13825020684201 6.073538411081e-08 158.244265746991 53.496345118964 2.95803882293437 0.00357514308714261 -712.534418515983 165.281189861084 -4.31104361672891 2.85872906627161e-05 MIER1 other 0.000614575508992321 0.412972000913597 1 2.95803882293437 -4.31104361672891 1.83846802916776e-18 565.240979933026 55.7440052376642 10.139941999559 1.1282756900463e-18 -165.252114963365 254.762990520378 -0.648650397084056 0.517569573250371 MAN1A2 other 2.57348754722903e-14 1 1.60790568588498e-14 10.139941999559 -0.648650397084056 0.00410491310033204 -5.56548949485921 55.9671838094074 -0.0994420143384761 0.920915821247375 -252.888243182834 89.8587984355977 -2.81428471764042 0.00552296789198774 SVIP other 1 1 1 -0.0994420143384761 -2.81428471764042 3.61120634087815e-05 147.652342433435 33.9812422057281 4.34511315211853 3.3476920134735e-05 -65.8385574654533 125.235596868753 -0.525717600359682 0.60024830013879 ZNF251 other 0.279904603481466 1 0.322516648578037 4.34511315211853 -0.525717600359682 7.36499099469537e-06 186.505704382988 52.2065504533451 3.57245791502084 0.000476751183302334 -398.811485533822 198.966094517274 -2.00441932833535 0.0468370615736565 DDRGK1 other 0.0615713247156533 1 1 3.57245791502084 -2.00441932833535 5.23808622497988e-06 705.243357165724 137.933965361471 5.11290569597966 9.53899745959459e-07 373.848476888601 252.818233278503 1.47872434689777 0.141310897953996 TFDP1 other 0.0444556377914042 1 0.0104347093210505 5.11290569597966 1.47872434689777 2.17058586756864e-17 70.2753600652381 9.01345028037552 7.79672133081432 9.87788086649045e-13 -89.6689595780884 35.0558895593324 -2.55788572776973 0.0115227019492754 ZNF607 other 3.00756377810311e-13 1 1.3417125580954e-08 7.79672133081432 -2.55788572776973 2.719725581881e-06 94.6467743016942 18.1079987951165 5.22679371545016 5.53171878755203e-07 75.6461338555551 78.6815362147753 0.961421668853357 0.33784732006097 ZNF334 other 0.0237758410368037 1 0.00614352688545529 5.22679371545016 0.961421668853357 0.00272712427739286 103.806124683286 105.509365103646 0.983856974035559 0.32671909044059 -304.987738121306 158.760633441432 -1.92105392571275 0.0565604051440451 HSD17B11 other 1 1 1 0.983856974035559 -1.92105392571275 3.54774954121866e-16 555.688517497599 64.2260624809085 8.65207200990688 7.24640665116776e-15 -369.171101839075 294.374623871671 -1.25408602475195 0.21176157606736 SZT2 other 4.84587109835057e-12 1 1.00971430277372e-10 8.65207200990688 -1.25408602475195 0.120302623450166 61.4257876298167 42.9499174250663 1.43017242668708 0.15470651410774 -111.262844568566 118.439112855176 -0.939409641683275 0.349001160585821 SULT1C2 other 1 1 1 1.43017242668708 -0.939409641683275 9.81130734889067e-05 44.2665692172503 11.8156219568558 3.74644427342779 0.000253591214035462 -6.20212304537872 17.596122996584 -0.352470998672989 0.724970126646897 RPS6KL1 other 0.720469136445488 1 1 3.74644427342779 -0.352470998672989 2.78693111358003e-12 489.742018254463 81.8994762067381 5.97979426654954 2.14888399518386e-08 -434.050682404113 175.399136619133 -2.47464549011221 0.0146662952131963 QRICH1 other 3.49118860598171e-08 1 0.000257844590582112 5.97979426654954 -2.47464549011221 9.16668193844078e-08 593.12468513854 101.669261326904 5.83386440894292 3.05809561377541e-08 651.660390428209 424.471702690459 1.53522693338035 0.126766818132299 DDX42 essential 0.000915018191095159 1 0.00036437209238134 5.83386440894292 1.53522693338035 4.45420522559682e-05 1009.07668304137 354.42843828101 2.84705337961996 0.00509728887062325 -4542.36969753143 1426.60412574775 -3.18404357281006 0.00180067549856073 RPL23A essential 0.341236662332973 1 1 2.84705337961996 -3.18404357281006 0.0289050974120644 92.6495999653321 43.2402693012808 2.14266935572919 0.0337008327614139 -57.2394303636333 100.133086931249 -0.571633534107801 0.568398285197971 SLC29A3 other 1 1 1 2.14266935572919 -0.571633534107801 0.00177179244635859 42.3994162881831 24.8584453237394 1.70563427181395 0.0900537777311654 -85.1352866910427 38.3959000873175 -2.21730149566577 0.0280390525382252 STYX other 1 1 1 1.70563427181395 -2.21730149566577 1.83935330608194e-06 669.59780150964 175.384413529143 3.81788659571151 0.000195972616466231 -859.001508205499 582.934884056419 -1.47358055196155 0.142676163727447 UBL5 essential 0.016386798603884 1 1 3.81788659571151 -1.47358055196155 9.60072529790637e-08 311.781279122401 53.9739871733168 5.77651004587145 4.0126971497029e-08 374.404545091462 218.416846828788 1.71417429803366 0.0884827957281352 HELZ other 0.000956520261430412 1 0.000475584866182788 5.77651004587145 1.71417429803366 0.000154636415115064 23.8774433150899 14.6579023119325 1.6289809283046 0.105374325485004 -73.3639706946977 29.1770939420743 -2.51443721024268 0.0129559775127781 TMEM116 other 1 1 1 1.6289809283046 -2.51443721024268 0.0339286460072225 88.1571271940014 59.4900923977231 1.48187914391902 0.140484244346676 -76.1914181912788 116.879983399338 -0.651877387173808 0.515484553665873 CARD11 og 1 1 1 1.48187914391902 -0.651877387173808 1.5892612716687e-05 19.2358480749218 6.17209091271573 3.11658534311154 0.00219832053752274 -30.9866111689213 13.9761470655101 -2.21710683378463 0.0281406371707652 ZNF485 other 0.128507666427131 1 1 3.11658534311154 -2.21710683378463 0.564979243565071 55.5196259914334 51.9593693094335 1.06852001341274 0.286936653949371 66.935896685238 103.432311378754 0.647146871156426 0.518488016597502 PEG3 other 1 1 1 1.06852001341274 0.647146871156426 1.03077377912082e-64 452.342849729979 16.0028834039488 28.2663341544038 1.28844040767164e-62 19.5727173140122 63.2226933742408 0.309583731242725 0.75729875811708 SDAD1 essential 1.50606356867343e-60 1 1.88215374752673e-58 28.2663341544038 0.309583731242725 1.21206555060074e-15 435.650901897859 57.6853991365721 7.55218666107243 3.70260553456547e-12 -267.599988011582 164.219424540436 -1.62952701095168 0.105272161751347 ZKSCAN8 other 1.64343968005954e-11 1 4.97741262011637e-08 7.55218666107243 -1.62952701095168 0.00172280480337565 25.9288468602438 18.8373438441846 1.37645981698468 0.170677347044081 -81.1478303766784 37.1425904177629 -2.18476496830093 0.0304178335957501 FAM109A other 1 1 1 1.37645981698468 -2.18476496830093 2.4309916645672e-06 75.9882161722877 15.8355472867985 4.79858477866668 3.76513747256505e-06 -31.1087210483545 44.0348129359303 -0.706457436156638 0.480978152734673 HYLS1 other 0.0213708477232103 1 0.0396367741635543 4.79858477866668 -0.706457436156638 4.488486849914e-09 11.4204012415306 2.22983554266459 5.12163387075782 9.11037531460555e-07 -15.9557529696385 9.84223061899075 -1.62115211351089 0.107071334405675 ZNF442 other 4.88571793613138e-05 1 0.009977683044556 5.12163387075782 -1.62115211351089 1.56559073575207e-10 32.1461667599328 6.71981866761082 4.78378485343298 3.97455438872569e-06 -42.2707907276458 17.2501243266646 -2.45046296056574 0.0153795380756009 ZNF813 other 1.8381600828465e-06 1 0.0417487192991747 4.78378485343298 -2.45046296056574 8.84113800900654e-06 206.552654018333 56.8349096891822 3.63425674726897 0.000388828425463162 -353.715067149862 164.703606654051 -2.14758543747507 0.0334441878009359 HOXC4 other 0.0734521745788263 1 1 3.63425674726897 -2.14758543747507 3.44923503601893e-05 304.377259161771 120.059541328029 2.53521924034464 0.0122551766274594 -328.732218659055 194.257254932589 -1.6922519510179 0.0926603929263218 PIM3 other 0.268315993451912 1 1 2.53521924034464 -1.6922519510179 1.23386946965076e-09 369.117151068818 78.0872887710143 4.72698126517402 5.23128806519164e-06 -1049.90385837275 382.516240801033 -2.74473014838306 0.00680110675286349 ASNA1 essential 1.3863757360996e-05 1 0.0544210897421886 4.72698126517402 -2.74473014838306 0.466387175857869 62.3949690852404 59.3595655570073 1.05113587843425 0.295007174727003 -69.0274245386805 234.776279619156 -0.294013622886664 0.769182943368319 ASPH other 1 1 1 1.05113587843425 -0.294013622886664 8.96536188198568e-13 419.957952221773 89.169178350842 4.70967614582497 5.60478010769315e-06 -231.162019860657 143.479523124877 -1.6111150554875 0.109256903565993 WWP2 other 1.13994576329448e-08 1 0.0581720127377472 4.70967614582497 -1.6111150554875 6.05970310833707e-07 268.317042356038 48.1009105354851 5.57821129307093 1.08435604996598e-07 163.440037411797 173.812901136022 0.940321669700991 0.348544534011631 UVRAG other 0.00563249403919931 1 0.00125720240433056 5.57821129307093 0.940321669700991 2.55543852240116e-11 111.126402577866 20.2249747205036 5.49451379364191 1.69850761221551e-07 -52.9093390107766 38.6367861729835 -1.36940321003648 0.17297600321345 ZNF26 other 3.09693594529797e-07 1 0.00194886763425607 5.49451379364191 -1.36940321003648 9.99050390191801e-07 210.438448566611 38.2352815044398 5.5037766242724 1.54425440958321e-07 189.223721191681 130.084386238576 1.45462285415748 0.147835626315139 ITSN2 other 0.00911333765932961 1 0.00177666469822548 5.5037766242724 1.45462285415748 3.32639513625238e-08 512.508185115084 131.919611793346 3.88500373938285 0.000151229200390174 -378.169611766915 231.248311501751 -1.63533999150541 0.104006951769784 MGEA5 other 0.000342718490888082 1 1 3.88500373938285 -1.63533999150541 0.12607388026846 197.111571008095 266.46383049449 0.739731057090582 0.460596703050734 -350.774803777285 416.734942601501 -0.841721602675183 0.401257511899277 MT1F other 1 1 1 0.739731057090582 -0.841721602675183 4.28872133873692e-07 169.316553314825 33.4373768532023 5.06369127154213 1.1977058999383e-06 -204.796806800347 132.637591100266 -1.54403291782895 0.124701594555366 TCAF1 other 0.00404169098962567 1 0.013025051661829 5.06369127154213 -1.54403291782895 0.00232349864138973 8.10251602604706 4.90732028919031 1.65110804849951 0.100808625743617 -40.183295186133 19.1259202652193 -2.10098623380788 0.0373145160438219 ZNF69 other 1 1 1 1.65110804849951 -2.10098623380788 3.70168572079673e-08 423.664679417901 98.1050660531085 4.31847912103288 2.78344365972017e-05 -246.465279278826 198.633451151321 -1.24080449617253 0.216540739523124 TXNRD1 essential 0.000380089089811408 1 0.2705507237248 4.31847912103288 -1.24080449617253 0.00146654267898848 205.032655455612 55.7643193599463 3.67677141600476 0.000354652565778382 112.767584781272 86.8928775037181 1.29777707932905 0.196853027262266 NRARP other 1 1 1 3.67677141600476 1.29777707932905 0.000489205282198412 10.5499169386804 4.80830666931007 2.19410234501415 0.0296975718545438 -15.0476801119141 9.66016394954745 -1.5577044230827 0.121316847934934 ZNF583 other 1 1 1 2.19410234501415 -1.5577044230827 3.90288811008936e-25 64.3929877524764 5.61341686845916 11.4712641625263 2.8889014444112e-22 -21.5875356730181 22.5758052454523 -0.956224393252453 0.340497453166604 ZNF568 other 5.62328118901676e-21 1 4.1577069587966e-18 11.4712641625263 -0.956224393252453 2.55099695413587e-12 115.886672074719 20.9207714691216 5.53931159975452 1.28313768601969e-07 -65.7657160975 40.7527756906073 -1.61377268132089 0.108623943978306 ZNF480 other 3.19971547957263e-08 1 0.00148279390996436 5.53931159975452 -1.61377268132089 2.35667819568726e-11 229.055673444755 41.7374103938189 5.48801833375549 1.65009463558546e-07 -108.020222323889 81.9858175199268 -1.31754766362651 0.189624667701477 ZNF587 other 2.85912198700778e-07 1 0.00189447365111566 5.48801833375549 -1.31754766362651 0.162165543682242 305.125079906244 180.118595666163 1.69402320053489 0.0924844474276098 10.2787944498065 469.215914280887 0.0219063210282618 0.982553873881009 TPM2 other 1 1 1 1.69402320053489 0.0219063210282618 0.000949857042447243 7.93925391399756 2.6043755269468 3.04842901181192 0.00270021466827512 -7.39576739671685 7.71281266830245 -0.958893689601905 0.339086648658196 FLVCR1-AS1 other 1 1 1 3.04842901181192 -0.958893689601905 2.19609448225036e-05 277.628205758639 66.0139904146213 4.20559648060826 4.4460427569448e-05 48.7708005507475 127.327448223799 0.383034461391425 0.702232891500309 SH3BGRL2 other 0.175094613069821 1 0.422685284902742 4.20559648060826 0.383034461391425 2.04329514070556e-06 19.2643157897045 7.06544691223354 2.72655304455675 0.00714245855772741 -53.9911293959262 19.6996938449426 -2.74070905979014 0.00685580003603599 ZNF808 other 0.018112195007448 1 1 2.72655304455675 -2.74070905979014 1.78966968687345e-13 360.45890567026 74.2564447238758 4.85424405936258 2.9868745966918e-06 -516.497927173917 172.172601755923 -2.99988454554529 0.00316021665155885 YTHDF2 other 2.31976984812536e-09 1 0.0316489232265463 4.85424405936258 -2.99988454554529 1.08413062062479e-10 58.3018873161255 8.01404147922437 7.27496700226315 1.6156620610653e-11 2.03416597280036 31.5026489245023 0.0645712675678588 0.948598564372403 NBR2 other 1.28209287195088e-06 1 2.14527608468251e-07 7.27496700226315 0.0645712675678588 6.74609740629164e-13 84.8514258908787 23.5695486634032 3.60004457881829 0.000426936403691352 -116.5108814157 35.8343433991982 -3.25137480873466 0.00140738172846028 TMA16 essential 8.60667107094687e-09 1 1 3.60004457881829 -3.25137480873466 0.00957594946169304 -1254.2882247909 433.367892730105 -2.89428046200933 0.00434142962539594 -2968.2624831626 1300.47576732544 -2.28244351624262 0.0238057169039047 HLA-DRB5 other 1 1 1 -2.89428046200933 -2.28244351624262 0.00138693194605262 38.5670259194342 14.0584225819429 2.74333949592403 0.0067895581404825 -24.6176644887177 22.8231672525346 -1.07862612652869 0.282408806774933 ATL1 other 1 1 1 2.74333949592403 -1.07862612652869 0.337007549774225 1.19724070810431 16.1067476768325 0.0743316237471324 0.940843609379383 -36.6965831075571 30.3159693079761 -1.21047038723259 0.227965103692817 CNGA1 other 1 1 1 0.0743316237471324 -1.21047038723259 6.98562156576852e-05 148.926500092728 52.340954459034 2.84531494757684 0.00507957093997416 -65.4946554718188 98.1776996835668 -0.667103178042594 0.50576644542362 MAFK other 0.522803917982116 1 1 2.84531494757684 -0.667103178042594 0.199859355172624 -2.69359331476327 6.13815511220502 -0.438827834345105 0.661405348206317 -43.6071262766946 24.1803725793399 -1.80341002329936 0.0732914597172502 C1orf228 other 1 1 1 -0.438827834345105 -1.80341002329936 3.5837812245541e-09 201.335833061624 35.6131104641925 5.65341893581745 7.49602101201921e-08 -47.6020948809912 107.900598910755 -0.441166178515496 0.659715484660299 ZNF43 other 3.92567395337656e-05 1 0.000876434776725286 5.65341893581745 -0.441166178515496 4.85957525739379e-08 317.076028739386 54.5148316731881 5.81632592466268 3.65446467722771e-08 -156.728325713041 211.395535025603 -0.741398467541234 0.459642752309269 GPN1 essential 0.000494656165450114 1 0.000434077314361107 5.81632592466268 -0.741398467541234 0.561921005739095 1.28171356178031 4.5103025402917 0.284174631375708 0.776653397806958 9.28029374976854 9.39804074580656 0.98747111241345 0.324940842685952 PLN other 1 1 1 0.284174631375708 0.98747111241345 0.567604074017261 -18.2481681280641 17.2041913532943 -1.06068153703545 0.290622822167824 -9.52484961371076 26.1660892617926 -0.364015024118213 0.716384447333563 C2CD4A other 1 1 1 -1.06068153703545 -0.364015024118213 5.0547482301817e-12 72.1203062621743 15.384610346066 4.68782144232962 6.06449919465414e-06 -139.59764591737 43.2189837150858 -3.23000760123479 0.00151533036911513 ZNF28 other 6.27445897812455e-08 1 0.062773631163865 4.68782144232962 -3.23000760123479 0.812030949425451 -14.6404016846083 23.9224418633291 -0.611994451413034 0.54143810654168 -20.7633742278076 47.2289701005015 -0.439632161862177 0.660815886718201 ITGBL1 other 1 1 1 -0.611994451413034 -0.439632161862177 0.233618578638578 74.2948772507518 53.1951866742787 1.39664661213935 0.164698968583084 -16.0765889266389 101.297372152369 -0.15870687052431 0.874125315711277 ZNF511 other 1 1 1 1.39664661213935 -0.15870687052431 2.25961791487498e-23 209.546160864063 21.3381062931391 9.82027917498186 6.9398072464155e-18 -165.447555843315 77.6906656030026 -2.12956800613278 0.0348394967975397 ZNF627 other 3.23916228097328e-19 1 9.85522027063465e-14 9.82027917498186 -2.12956800613278 0.0626619745038043 -6.00793033742807 27.2971768354227 -0.220093468773363 0.826101657897143 -96.6287742277753 46.3501984251943 -2.08475427313924 0.03880931439711 KCNRG other 1 1 1 -0.220093468773363 -2.08475427313924 0.00106739804987301 67.1701945691684 23.9700466532705 2.80225547913164 0.00571838605072297 -31.4403820112608 35.2096402660902 -0.892948118005639 0.373260362211458 WDHD1 essential 1 1 1 2.80225547913164 -0.892948118005639 1.90710041496142e-05 48.6258540387929 12.3461922699951 3.93853043719139 0.00012392182002267 -70.0620541475331 41.3053158628469 -1.69619945239427 0.091868630889062 ZNF789 other 0.152911311271606 1 1 3.93853043719139 -1.69619945239427 8.50390722425429e-06 1216.25771941245 306.653566431217 3.96622721061767 0.000112148682383799 -2099.72184077209 1155.11011426968 -1.8177676871089 0.0710688165421253 CTNND1 other 0.0707695159202442 1 1 3.96622721061767 -1.8177676871089 9.41469270208527e-08 911.600533308579 209.770719898927 4.34569959881823 2.47557505020273e-05 -1416.12240782074 688.315971490188 -2.0573725824709 0.0412940105671213 DDX39B other 0.000938550715470881 1 0.241739903652296 4.34569959881823 -2.0573725824709 0.016247538838626 4.29560106744263 2.40877684039536 1.7833121754598 0.0764924366243506 -10.6077872092462 7.19680949220821 -1.47395692782072 0.142521251528267 RD3 other 1 1 1 1.7833121754598 -1.47395692782072 0.790453630302948 10.3401814018769 20.3856445040431 0.507228574491532 0.612828197049783 -25.9074667482298 85.2976617751893 -0.303730093053566 0.761804631468305 ARC other 1 1 1 0.507228574491532 -0.303730093053566 2.56517875628372e-07 161.474945963921 28.5240737163465 5.6610057725164 7.29321576133235e-08 -36.11725829246 113.080279131992 -0.319394845588438 0.749865659409884 NUDT16 other 0.00246385419541052 1 0.000853087447603045 5.6610057725164 -0.319394845588438 1.3424885361729e-10 235.408747901221 40.3426996145078 5.83522545964088 3.03770385170306e-08 -305.227922727186 124.708509204019 -2.44753084352763 0.015500426219847 TLK1 other 1.58037750478274e-06 1 0.000362003168007454 5.83522545964088 -2.44753084352763 2.20252098228649e-21 1013.04757147614 102.813214161179 9.85328179593725 4.84107646009477e-18 292.739016935443 164.685040248494 1.77756896736782 0.0774612561733509 LRBA other 3.13572912248128e-17 1 6.8811060803787e-14 9.85328179593725 1.77756896736782 0.109797813327385 -6.70312991916878 17.3459438859333 -0.386437887914805 0.699727403467765 -65.8095027474916 33.5299886803246 -1.96270578481014 0.0515554837365197 MMP17 other 1 1 1 -0.386437887914805 -1.96270578481014 0.000481769086544836 67.8154670831553 76.6832997191637 0.884357706717304 0.377937565144269 -391.559810742718 126.370861798801 -3.09849759010216 0.00232819850052341 BAZ1A other 1 1 1 0.884357706717304 -3.09849759010216 5.25854629730866e-06 363.334493489125 86.2750855478798 4.21134897962502 4.26344904871149e-05 -107.312104053973 189.951137704625 -0.564945834759062 0.572916955098762 COPS8 other 0.0446082482400693 1 0.405965618418309 4.21134897962502 -0.564945834759062 0.0115119540052483 -65.7143816706305 27.2491060109847 -2.41161605977604 0.0170435392233723 26.5950662730521 42.6612544133293 0.62340094398965 0.533931474464724 CCDC69 other 1 1 1 -2.41161605977604 0.62340094398965 1.21669756030429e-06 198.018201639389 41.324335865144 4.7918060264923 3.85786633596554e-06 -239.246704201511 154.822094574599 -1.54530078448353 0.124326019727154 MDM4 other 0.0110171964085553 1 0.0405616066563416 4.7918060264923 -1.54530078448353 0.0679684565442195 26.0601168855399 15.7144158389126 1.65835734224424 0.0992547382226815 -39.2439149428263 48.6373882158158 -0.806867234907673 0.420971411612804 RYR2 other 1 1 1 1.65835734224424 -0.806867234907673 6.32176290399936e-23 419.498572739321 40.8130041138132 10.2785516981178 3.59671247805201e-19 -62.8912127892754 97.7049713108143 -0.643684880569781 0.520743476667395 KLHL9 other 9.05150012594629e-19 1 5.13754410364949e-15 10.2785516981178 -0.643684880569781 0.526921713012168 -23.4412010460025 31.6085106385834 -0.741610426192894 0.459475284067669 -83.0673402757361 74.3910173467382 -1.11663132510418 0.26592566139635 FAM3D other 1 1 1 -0.741610426192894 -1.11663132510418 0.512691674576147 15.7518811233362 20.4746701001994 0.769335039160545 0.442850327654137 -37.637002026046 62.5812964575632 -0.601409752697724 0.548434495194408 STK39 other 1 1 1 0.769335039160545 -0.601409752697724 2.77368600709511e-17 468.861914825411 65.9115406199958 7.11350258869796 4.23849355777956e-11 -601.70608593444 191.374335469674 -3.14413154960262 0.00200609539071104 C6orf89 other 3.83878143381964e-13 1 5.58082446752834e-07 7.11350258869796 -3.14413154960262 0.16696560023041 3.7972766895249 2.30055757858383 1.65058972002014 0.100928689650164 -3.82530671677767 7.61088302899945 -0.502610104793656 0.615980474158011 FAM19A2 other 1 1 1 1.65058972002014 -0.502610104793656 6.44835246894453e-16 500.827735002962 75.9302703014466 6.5958903216682 6.39863149646313e-10 -72.0371717855427 109.794214753898 -0.65611081555629 0.512731929398008 TTC37 other 8.78265606270245e-12 1 8.12434241105924e-06 6.5958903216682 -0.65611081555629 0.000964271284544704 61.7434013730186 38.9064128109075 1.58697235011367 0.114653112162525 -190.514240198045 85.0729299793686 -2.23942257830131 0.0266193682722393 TUSC1 other 1 1 1 1.58697235011367 -2.23942257830131 0.547039264889798 -23.1013266709887 36.1872088429976 -0.638383766242279 0.52416599042544 24.8862815789337 64.9013285679231 0.383447952885721 0.701913072703288 PAPSS2 other 1 1 1 -0.638383766242279 0.383447952885721 1.24018105648957e-19 250.693319511689 29.9032090406368 8.38349219212594 3.02921836972798e-14 -63.5548729658654 48.1345243862635 -1.32035942551045 0.188674047707477 FAN1 other 1.74853127154465e-15 1 4.18789439614893e-10 8.38349219212594 -1.32035942551045 0.000960065462992284 68.3269029591807 20.6823870091228 3.30362752273431 0.00119185041745157 -64.8367375475158 63.5558332432218 -1.02015400064683 0.309287102425582 ABCA4 other 1 1 1 3.30362752273431 -1.02015400064683 2.04536697951229e-09 614.157554683118 107.700937886306 5.70243460025808 6.14618652229273e-08 -811.627223780144 375.699683800694 -2.1603085090982 0.0323475751597919 IPO9 essential 2.27240271423816e-05 1 0.000722607149425956 5.70243460025808 -2.1603085090982 4.96857467204642e-10 116.754088611359 21.6250195163895 5.3990281267895 2.63069025568444e-07 -39.5115472296561 45.2900574177582 -0.872411065086519 0.384406916505424 CEP290 other 5.69498028909961e-06 1 0.00298083512871604 5.3990281267895 -0.872411065086519 0.00723441439426965 5.99753934485054 3.18875771253618 1.88083883616243 0.0619321484558451 -16.9369457117958 9.6853049668021 -1.74872611341097 0.0823840152604669 SSBP3-AS1 other 1 1 1 1.88083883616243 -1.74872611341097 5.65685259475471e-05 116.465815425089 31.945456905581 3.64577084526664 0.000375820886513645 -51.337459818336 48.3547000556867 -1.06168500185534 0.290219863289647 TOGARAM1 other 0.427884330267246 1 1 3.64577084526664 -1.06168500185534 0.0799332508746222 10.1101083032491 15.7095061214231 0.643566272873589 0.52094849085969 -46.8216004813477 32.50670752534 -1.44036735940879 0.152078637276967 DLL1 other 1 1 1 0.643566272873589 -1.44036735940879 1.95223729487525e-06 76.8511700625379 22.5869767971636 3.40245490809503 0.000872566430255676 -323.315634456324 90.895980754491 -3.55698493786646 0.000513530335217983 ANKRD13B other 0.0173358671784922 1 1 3.40245490809503 -3.55698493786646 0.00109447550693709 100.282698092019 41.7772757916121 2.40041257338646 0.0175940062304217 -160.123505034764 105.726782513587 -1.51450277051783 0.131988783122736 ECI2 other 1 1 1 2.40041257338646 -1.51450277051783 2.19035856873957e-14 197.097220680772 26.1077966721446 7.54936248186207 5.86505531723365e-12 -35.8167293896863 68.0825665332726 -0.526077837741066 0.599697292780483 UNC13B other 2.90485353386241e-10 1 7.85800111402965e-08 7.54936248186207 -0.526077837741066 7.87764391068241e-10 17.4104726212783 3.24845563922446 5.35961532337099 3.01447969593462e-07 -10.2939621070165 9.71907039109773 -1.05915089538248 0.29120030532375 TEX45 other 8.94112583862453e-06 1 0.00340395047264938 5.35961532337099 -1.05915089538248 4.95263743379033e-15 1017.16567671991 153.760642443576 6.61525381628896 5.69286306952334e-10 -321.439377775217 268.125730714368 -1.19883823502804 0.232420470628648 LDB1 other 6.64445838117311e-11 1 7.24246039704759e-06 6.61525381628896 -1.19883823502804 0.0107030764647838 -4.03441798054348 39.136578403274 -0.1030856080205 0.918028279346922 -211.12473163368 80.3790128605506 -2.62661513397732 0.00948941723181843 PPP1R14C other 1 1 1 -0.1030856080205 -2.62661513397732 1.41895847468834e-15 241.128989416892 43.7461290043956 5.51200745996664 1.43751735298558e-07 -164.037379816006 68.1701893037197 -2.40629198028434 0.0172847038889725 CTR9 essential 1.92126977472802e-11 1 0.00165630749410999 5.51200745996664 -2.40629198028434 0.496901033168398 -10.2752851620858 16.6829583066111 -0.615915053747629 0.538859846764012 -28.6775119163366 24.1956759648458 -1.1852329299666 0.237751086350797 SMOC1 other 1 1 1 -0.615915053747629 -1.1852329299666 0.00293709035518065 83.5394312612844 38.1131091691324 2.19188182445484 0.0300772338268212 -88.3572887112027 80.5834789656112 -1.09646902622446 0.274797199573161 MSRB1 other 1 1 1 2.19188182445484 -1.09646902622446 4.91275829359052e-12 280.182144093198 35.7525119166573 7.83671213777454 6.72591029711852e-13 121.214135055539 146.084624734396 0.829752859179565 0.407946454933299 ZNF652 other 6.09968069732199e-08 1 9.15867205158629e-09 7.83671213777454 0.829752859179565 4.50449418240628e-07 254.357908302879 45.7680792925318 5.55753949553186 1.20696879238275e-07 56.4896898116274 148.189535679382 0.381198912275741 0.703591474212055 SMURF1 other 0.00423692722797135 1 0.00139682498342456 5.55753949553186 0.381198912275741 3.71829109025691e-06 581.030239007 139.948575552421 4.1517409999601 5.53173335912942e-05 -303.423032483825 272.800648861252 -1.1122518723852 0.267821203280007 SLC5A3 other 0.0320628240712853 1 0.520425474426896 4.1517409999601 -1.1122518723852 1.73416647624135e-20 79.9846421842226 9.91192926015961 8.06953319428095 1.98050275628086e-13 -29.3047495467311 20.9352779208628 -1.39977838639189 0.163617354657122 GPATCH3 other 2.45557973035775e-16 1 2.71388292693167e-09 8.06953319428095 -1.39977838639189 1.74331977415845e-10 1390.13968372251 211.969207693604 6.55821521837227 8.96170258055015e-10 31.8053049347031 365.450775606215 0.0870303391255469 0.93076746670431 CDC42BPB other 2.04160178751696e-06 1 1.13284882320735e-05 6.55821521837227 0.0870303391255469 0.0626575071853187 824.220377312003 1142.65233378712 0.721322096792358 0.471819410360949 -5690.39203315559 3329.28366738151 -1.70919410950377 0.0894558587371625 RPL10A essential 1 1 1 0.721322096792358 -1.70919410950377 0.0135002704648877 25.562399120053 8.62534786120031 2.96363689110339 0.00352375885257549 25.777189647979 36.2259021952474 0.711567913727784 0.477808858088071 COLGALT2 other 1 1 1 2.96363689110339 0.711567913727784 0.0863480114815519 19.2273959650502 8.99981339588922 2.13642162556754 0.0342784534474705 -0.283021769590929 36.613124432398 -0.00773006330321511 0.993842703300865 APCDD1L other 1 1 1 2.13642162556754 -0.00773006330321511 0.00108456193770963 186.351439886569 71.1267918429975 2.61998938877932 0.00970983314267221 -130.109454195799 148.82898614422 -0.874221195525165 0.383414187145201 RASSF9 other 1 1 1 2.61998938877932 -0.874221195525165 4.38120573175013e-06 41.7607230635061 18.0665073759776 2.31149951644964 0.0221397743230139 -41.6616542015732 25.6903821001772 -1.62168293329066 0.106930203500251 FAM169A other 0.0374854674760729 1 1 2.31149951644964 -1.62168293329066 1.26720781644989e-10 72.8865622489164 10.3690560083964 7.02923797401578 6.56259212525995e-11 -34.0776090385172 40.0219818406085 -0.851472302751887 0.39584650504984 ZNF830 essential 1.49365785324949e-06 1 8.59765194330306e-07 7.02923797401578 -0.851472302751887 1.3869148695092e-28 810.420387562545 89.5042953119047 9.05454184895139 5.74120278932593e-16 -237.227561533994 175.001307396783 -1.35557593861927 0.177218814394675 CNOT7 other 2.00742058212762e-24 1 8.06638991900292e-12 9.05454184895139 -1.35557593861927 3.30821041471567e-19 1500.24368652229 142.679373382399 10.5147902668555 1.16543729050076e-19 847.220814041954 288.799558601247 2.93359455999631 0.00388461004862706 TMEM184B other 4.65365959038053e-15 1 1.66704150033229e-15 10.5147902668555 2.93359455999631 9.59484933607627e-19 842.977049892266 93.284190075277 9.03665507747898 6.38897173162527e-16 149.844323996281 213.804421631071 0.700847638477953 0.484455696483357 MTOR essential 1.34491003143781e-14 1 8.97305130056881e-12 9.03665507747898 0.700847638477953 0.166923547332803 94.1038889557783 49.9431409431865 1.88422047910097 0.0615096635056314 48.3611517225959 86.0112450464419 0.562265453737859 0.57479155857279 SCAMP5 other 1 1 1 1.88422047910097 0.562265453737859 0.0754470647125847 92.6348027600871 46.3052870436193 2.00052323772069 0.0474058446572743 -3.4101411250707 123.702624204634 -0.0275672496601972 0.978047128288019 ZNF521 other 1 1 1 2.00052323772069 -0.0275672496601972 0.00134231507184481 58.077108798978 15.7682252678253 3.68317345880914 0.00031832876814952 90.6231174821084 29.541261567177 3.06767932967355 0.00254930893422066 ALPK2 other 1 1 1 3.68317345880914 3.06767932967355 9.45290457406519e-14 222.880468454855 31.5422785186018 7.06608650111984 5.17547974874827e-11 -232.392406497922 102.810079669058 -2.2604048868164 0.025197666338018 LRIG2 other 1.23407669214421e-09 1 6.79747510200597e-07 7.06608650111984 -2.2604048868164 0.0010663007530658 118.026213931179 54.3273640408851 2.17250028627113 0.0313988591597082 -373.21556290888 153.889108074034 -2.42522403034094 0.0164949720960613 PNP other 1 1 1 2.17250028627113 -2.42522403034094 0.319627456586493 -11.8241863030067 13.0962023358238 -0.90287138208474 0.368041755981877 -29.6078323242304 19.8348687748515 -1.49271631994712 0.137611792910339 PAX9 other 1 1 1 -0.90287138208474 -1.49271631994712 9.62020365412937e-16 297.012601568557 35.7621511083641 8.30522192774614 5.09207667797174e-14 -586.268453673602 240.816858071243 -2.43449922222704 0.0160706881502565 FOXJ3 other 1.30575024197498e-11 1 7.02248294659083e-10 8.30522192774614 -2.43449922222704 7.54854944654565e-19 695.277569276441 94.9357228140528 7.32366646260497 1.31531477683172e-11 -800.166778473859 284.641801514221 -2.81113587047714 0.00558757820304574 ZNF358 other 1.05906148735036e-14 1 1.74976324761924e-07 7.32366646260497 -2.81113587047714 8.10636840082064e-07 180.905102898482 49.8396806371601 3.62974041137013 0.000384826278471874 -151.523018649089 104.358923314003 -1.45194118372777 0.148539105248133 SFT2D1 other 0.00745056319719425 1 1 3.62974041137013 -1.45194118372777 6.47811326482398e-10 278.673175377408 39.8528337626374 6.9925560886631 1.01533837105137e-10 148.009796527715 72.2077130485373 2.04977820621773 0.042252655203288 CHAMP1 other 7.38278978806876e-06 1 1.32318896515415e-06 6.9925560886631 2.04977820621773 0.000134029949496942 123.542478472411 29.6045547459423 4.17309024008691 5.00691519862832e-05 50.9703637449248 53.0254170086886 0.961243996187205 0.337936337935175 INPP5F other 0.966087875973961 1 0.473704246942226 4.17309024008691 0.961243996187205 4.1752867250322e-07 232.097639718038 51.1699200886962 4.53582181320057 1.14743710846291e-05 -46.8396755098166 83.1117822729189 -0.563574432274914 0.573863508521801 ARHGAP11A other 0.00393980055374039 1 0.115825925232237 4.53582181320057 -0.563574432274914 0.0585374679067981 7.57100944262092 6.28055761452121 1.20546771597415 0.229908439638883 55.579812703203 25.6078840855476 2.17041800554583 0.0315380587996677 SUCNR1 other 1 1 1 1.20546771597415 2.17041800554583 9.50252072859145e-05 679.032944661314 331.638861803674 2.04750716176107 0.0423074843979445 -1399.06249459235 700.985728655583 -1.99585018267862 0.0477134484513077 HMGN2 essential 0.699005424795187 1 1 2.04750716176107 -1.99585018267862 0.0550517203767274 355.062261753494 193.330927460383 1.83655179446781 0.0682295180662983 -234.965507681646 332.301134583644 -0.707086083157811 0.480595605028915 SELENOM other 1 1 1 1.83655179446781 -0.707086083157811 2.17510457645807e-06 223.960829543449 77.7716104235883 2.87972472633177 0.0045551382163022 -298.025444488344 154.402213944077 -1.9301889323704 0.0554454133304514 UBE2J1 other 0.0192366248741952 1 1 2.87972472633177 -1.9301889323704 0.000264827840921064 97.5981800973369 26.0661672007595 3.7442474509445 0.00026280073646866 -15.4617810831976 82.1931829197984 -0.188115127483075 0.851056863939927 GJC2 other 1 1 1 3.7442474509445 -0.188115127483075 1.74901611890743e-14 392.172768454452 44.3255323839829 8.84755912364774 1.97072552267068e-15 222.047799992354 169.633754328069 1.30898358567787 0.192489783797979 OPA1 essential 2.32251850429718e-10 1 2.75704500621628e-11 8.84755912364774 1.30898358567787 0.0370030656149501 34.3298497863937 14.162600313658 2.4239792853073 0.0165100244029575 10.0181542560523 22.7732619397751 0.439908621019936 0.660620046017124 RYR3 other 1 1 1 2.4239792853073 0.439908621019936 2.90160925376423e-09 98.6320952258232 17.1902506514292 5.73767638563332 5.08446307519808e-08 -73.2317620366877 53.3456072035026 -1.37277961346139 0.171856234667006 ZNF277 other 3.19699307579743e-05 1 0.000599864953611869 5.73767638563332 -1.37277961346139 7.15268794935417e-06 18.9622587968218 9.49453001681218 1.99717719184045 0.0476026663709515 -110.530741581536 29.4742548482747 -3.75007755583704 0.0002513414282012 KTI12 essential 0.0598679981360944 1 1 1.99717719184045 -3.75007755583704 0.219311766176878 167.834762648272 96.5609490622042 1.73812254620813 0.0841880440794897 140.901633613758 402.043097696182 0.350464003538834 0.726469408448335 SELENOT other 1 1 1 1.73812254620813 0.350464003538834 0.512963418412625 -6.18817348415796 7.09969429497561 -0.871611259168901 0.384832210121069 19.3955717578955 37.7587157447794 0.513671383555389 0.608247788587157 ARHGEF15 other 1 1 1 -0.871611259168901 0.513671383555389 0.458783253662323 -15.7880550330443 15.1179176017435 -1.0443273636591 0.297970473443646 -3.9771968894367 26.0614764986256 -0.152608271816313 0.878906965529439 CES1 other 1 1 1 -1.0443273636591 -0.152608271816313 0.654899607536779 20.018139801093 22.3937499017208 0.89391637796021 0.372761519158456 33.6893247501355 62.3997126603197 0.539895510954151 0.590048938630346 CD3E other 1 1 1 0.89391637796021 0.539895510954151 7.55832084657985e-15 414.602865752559 47.4191982372164 8.74335461511794 7.9066078247137e-15 238.558428258655 123.657341118496 1.92918937202485 0.0558055479479135 RUSC2 other 1.01062308039619e-10 1 1.10115327174788e-10 8.74335461511794 1.92918937202485 3.37283583204202e-07 13.7795945062132 5.87960357492563 2.34362645892968 0.0203668434957454 -37.8104062204782 11.7699333719362 -3.21245711642106 0.0016007757030751 FICD other 0.00320520589118953 1 1 2.34362645892968 -3.21245711642106 2.2699275319151e-08 347.846656528706 138.60377217809 2.50964783326216 0.0131054685713598 -550.022159659146 209.245819955401 -2.62859329651784 0.00943114698981864 OSTC essential 0.00023661724592683 1 1 2.50964783326216 -2.62859329651784 0.00208438615350499 113.157943212266 93.7459090115983 1.20707073412948 0.229455012438278 -346.893560211373 140.193749588801 -2.47438677707699 0.0145500848079875 R3HDM4 other 1 1 1 1.20707073412948 -2.47438677707699 0.00507922407002661 124.702762118096 42.3383522784442 2.94538533993884 0.0037231163941423 -186.800839377462 178.204816590953 -1.0482367589774 0.296161293622435 TSEN15 other 1 1 1 2.94538533993884 -1.0482367589774 1.04561435647828e-07 143.399298382649 26.4238872219595 5.42688126005463 2.45718938558916e-07 -2.45281040915128 50.834404202323 -0.0482509915802101 0.961584977586973 LTN1 other 0.00103892242459682 1 0.00278964710945937 5.42688126005463 -0.0482509915802101 8.29833460433333e-11 179.390814558059 25.2823184542449 7.09550490326726 4.24670462296542e-11 -114.941941074524 100.324115371467 -1.14570600148261 0.253671326645489 RUNDC1 other 9.85676184302713e-07 1 5.59121130659627e-07 7.09550490326726 -1.14570600148261 3.84685941416607e-05 1972.61581694099 431.07528401166 4.57603553278092 1.00972500124149e-05 -627.70420179312 1932.67567279481 -0.324785069025786 0.745811853058194 CCDC152 other 0.296708266614629 1 0.102507282126036 4.57603553278092 -0.324785069025786 0.000345880645266192 8.58983603137003 3.36731944184571 2.55094183362114 0.0116994418700764 -5.877308877134 4.53198762861127 -1.29685015908461 0.196585437938481 STKLD1 other 1 1 1 2.55094183362114 -1.29685015908461 0.628782329116479 0.622468063749408 12.4430989276467 0.0500251639377695 0.960166741327895 19.3179373301389 22.3265216983189 0.865246167368448 0.388240883180224 GRK5 other 1 1 1 0.0500251639377695 0.865246167368448 6.55506010086122e-25 653.508845517032 63.1072468240063 10.355527746909 2.69834623548556e-19 -335.919517334806 163.24939128407 -2.05770762569199 0.0413493780232045 DCAF12 other 9.43928654524015e-21 1 3.85539710126176e-15 10.355527746909 -2.05770762569199 0.846699313131873 -5.45662617200462 16.9688047662772 -0.321568091987763 0.748215961812571 19.6841719349116 63.5021415958059 0.309976505362642 0.756997891733078 SFMBT2 other 1 1 1 -0.321568091987763 0.309976505362642 0.000445729178890801 14.4100499454533 3.60565379799011 3.99651512673953 0.000101639145907326 5.53167046390644 18.3842436316517 0.300891925430247 0.763924979216658 ITPRIPL1 other 1 1 0.929388350176591 3.99651512673953 0.300891925430247 1.85136621667456e-05 159.165518775028 47.0603106016567 3.38216039673619 0.000911833425500795 -191.180339775925 86.9858483210058 -2.1978326758441 0.0294539856808588 SMC5 essential 0.148627679874634 1 1 3.38216039673619 -2.1978326758441 7.73399928554902e-05 82.7725858892928 33.2247663140804 2.49129174022856 0.0138095138317094 -293.058464109197 105.483535907994 -2.77823891270398 0.00615952695962299 PRMT6 other 0.575718906816269 1 1 2.49129174022856 -2.77823891270398 2.80396459817132e-05 116.957218171621 25.919583634589 4.51231083880316 1.29250390784437e-05 -29.238538979248 90.4168484218825 -0.323374896267361 0.746864745880921 SHISA4 other 0.220868291397955 1 0.129844942582045 4.51231083880316 -0.323374896267361 1.65588920876392e-07 325.724004664656 77.3491992676778 4.21108437771207 4.32213667956881e-05 -222.733519501923 124.288497379561 -1.79206864832973 0.0750981368154999 CIPC other 0.00161912846832936 1 0.411380969161359 4.21108437771207 -1.79206864832973 0.0713480120784419 92.620737389123 128.881268764711 0.71865165727235 0.473473541993561 -719.996720723949 392.340822648091 -1.83513078212039 0.0684670510703231 CAPZA2 other 1 1 1 0.71865165727235 -1.83513078212039 0.000256052157059359 166.028974204277 67.1587873214342 2.47218541052017 0.0145240711511537 -630.483776505733 291.865173819226 -2.16018844679372 0.0323149950304317 TOP1 essential 1 1 1 2.47218541052017 -2.16018844679372 0.00240779181110186 277.615181408313 81.608142534233 3.40180737837354 0.000863873840745712 37.2523630489005 161.203676833076 0.231088792642582 0.817569351440409 PRC1 essential 1 1 1 3.40180737837354 0.231088792642582 1.49402065456018e-08 229.660050426479 40.7867640474147 5.63074947940217 8.2135356249801e-08 515.02153854407 165.039463125328 3.1205963034003 0.00215312579746658 MAP3K3 other 0.000157619179056099 1 0.000958026795297679 5.63074947940217 3.1205963034003 1.86185870639972e-06 1461.05688879907 341.25531260011 4.281418735043 3.25376315770136e-05 -26.5493284061453 506.89329493751 -0.0523765626243258 0.958296527610223 SREBF2 other 0.0165761280630767 1 0.314085757612913 4.281418735043 -0.0523765626243258 1.92758416939929e-09 118.809032986087 30.0574318956953 3.95273399931092 0.000119978733868681 -159.370326282907 66.8122009470769 -2.3853476464448 0.0183461770043603 C1orf174 other 2.1438591132059e-05 1 1 3.95273399931092 -2.3853476464448 0.00796308667274702 160.809855605675 53.4437322865181 3.00895631209951 0.00306048375333266 4.72510898873585 150.907501162471 0.031311293026108 0.975061566070018 POU3F3 other 1 1 1 3.00895631209951 0.031311293026108 0.310139881950585 -4.4441720166463 42.2798703225832 -0.10511318939104 0.916428316850651 -143.738458560505 98.8528840833445 -1.45406438965723 0.148045824170418 RASGEF1A other 1 1 1 -0.10511318939104 -1.45406438965723 9.4450664012347e-13 262.470705798519 49.7642380293881 5.274283625995 4.44551309001954e-07 -140.690224218219 67.9755075657345 -2.06971936299507 0.0401490026249012 SPOUT1 other 1.20037348893292e-08 1 0.00497052818595085 5.274283625995 -2.06971936299507 3.10402680073142e-13 171.892748267898 21.3775458816607 8.04080829574368 2.08422862490158e-13 -70.8684526558882 107.833656956884 -0.657201607140377 0.512019739103962 KIAA0753 other 3.99736571398192e-09 1 2.85497637039018e-09 8.04080829574368 -0.657201607140377 8.12505237631911e-09 97.3991614033445 17.8819528722513 5.44678548809318 1.98856829072538e-07 -20.6149042608951 34.2605945684092 -0.601708888026815 0.548252715789553 DCLRE1A other 8.70843113693882e-05 1 0.00227054727435024 5.44678548809318 -0.601708888026815 3.05030940513001e-08 727.083284497912 128.909957786986 5.64024142882243 9.1516273767183e-08 -34.9095970216149 322.065438758528 -0.108392869337926 0.91384036847457 ATG9A other 0.000315157967738033 1 0.00106552397547131 5.64024142882243 -0.108392869337926 0.00226381974934183 558.393557880969 219.176746600491 2.54768613250197 0.0119080508878696 -168.942773054284 382.092127138815 -0.442151934192841 0.659051943101815 APRT other 1 1 1 2.54768613250197 -0.442151934192841 4.73513062767163e-05 112.048996575286 24.3830521839692 4.59536385067302 8.89861802094135e-06 64.1187730589147 100.98885067949 0.634909424431513 0.526423584793296 TBKBP1 other 0.361432520810176 1 0.0907481065775599 4.59536385067302 0.634909424431513 0.00239637401216983 81.0794584001427 43.3343605358728 1.87102007269783 0.0632644950615138 -246.492965638523 130.059435627174 -1.89523324047872 0.0599600311246158 CCDC167 other 1 1 1 1.87102007269783 -1.89523324047872 2.67862865260887e-07 14.1800598205384 3.74664664699515 3.78473369830884 0.000219937768426033 -13.0464334269918 6.12344058884909 -2.13057238617609 0.0347125847203388 ZFP2 other 0.00256773342639087 1 1 3.78473369830884 -2.13057238617609 0.0238705894363707 29.4784388637999 15.7345598385742 1.8734835398148 0.0629734520342278 -16.8036371035585 24.3653945798282 -0.689651753781569 0.491493130789091 SOWAHA other 1 1 1 1.8734835398148 -0.689651753781569 7.72110963508175e-08 53.0765854104926 10.9345235556818 4.85403731952391 2.91152863877242e-06 2.2234913171102 24.4511559690321 0.0909360408123977 0.927660071743624 L3MBTL3 other 0.00077535382955491 1 0.030870938156904 4.85403731952391 0.0909360408123977 0.462481618025683 22.7410419052275 27.3226963875801 0.832313238146025 0.4065209902071 -8.05406379064112 41.7856801759442 -0.192746983098717 0.847411081160604 MFAP3L other 1 1 1 0.832313238146025 -0.192746983098717 5.31706895291996e-06 238.020492740368 71.2425124882595 3.34098959212862 0.00104612832231986 -120.210958042758 105.935350422499 -1.13475773255409 0.258228632463357 NAGA other 0.0450781105828554 1 1 3.34098959212862 -1.13475773255409 1.82053719783041e-05 121.799527836398 35.2515147646082 3.45515727904782 0.000710737467634018 -137.128660786129 77.1272806377453 -1.77795275098835 0.0773850267187232 KIF1BP other 0.146280163845673 1 1 3.45515727904782 -1.77795275098835 0.545192582210922 -650.877838139016 698.074515168309 -0.932390201899988 0.352633246284729 -2849.42669591865 3211.91759712478 -0.887141905031864 0.376422701242082 TGM2 other 1 1 1 -0.932390201899988 -0.887141905031864 8.11179472631914e-14 502.572387085705 94.9313615390453 5.29406066591594 3.97305175686095e-07 -255.747507644043 139.787530144009 -1.82954450501109 0.0692150360446812 PJA2 other 1.06086051430802e-09 1 0.00445339371426544 5.29406066591594 -1.82954450501109 0.0693287067674227 -50.3130936214749 71.0290681776268 -0.708345117180107 0.479801762607444 -345.901654844497 149.217404801014 -2.31810528608085 0.0217595123496637 SGMS1 other 1 1 1 -0.708345117180107 -2.31810528608085 0.31405252515249 -14.7170899646665 10.1498533500613 -1.44998055214045 0.14907145985156 -2.93679219641835 32.072018458955 -0.091568673801332 0.92715821913831 RNA5S12 other 1 1 1 -1.44998055214045 -0.091568673801332 0.297947947521536 -16.8216787968472 10.9957397274008 -1.52983602866922 0.128082563211587 -9.51435991906503 34.744892890983 -0.273834774765825 0.784573835186726 RNA5S11 other 1 1 1 -1.52983602866922 -0.273834774765825 0.318843855382418 -14.7936761996799 10.3145777853069 -1.43424932242534 0.153502640583148 -2.34053845921541 32.5925230362756 -0.0718121287084887 0.942843405050211 RNA5S3 other 1 1 1 -1.43424932242534 -0.0718121287084887 0.314066805912704 -15.1189789508652 10.1632571953262 -1.48761156588835 0.138871890222496 -7.37321444749797 32.114372605161 -0.229592355365306 0.818709302015758 RNA5S1 other 1 1 1 -1.48761156588835 -0.229592355365306 0.358105242833604 -13.9658819798871 10.1284132586852 -1.37888153091613 0.169905172705368 -4.26402017334583 32.00427097703 -0.133232848091 0.894180944569795 RNA5S5 other 1 1 1 -1.37888153091613 -0.133232848091 0.0115495663526066 3.57685417413113 2.38629606028738 1.49891467100707 0.135983508810188 -5.65129412567607 4.07737877404255 -1.38601156253949 0.167786772114082 SNORA31 other 1 1 1 1.49891467100707 -1.38601156253949 0.000437834852608561 10.999277175424 2.72645389314237 4.03427954644294 8.62275136738688e-05 0.885056991937745 10.9135845805983 0.0810968188684005 0.935470942335592 SNORD104 other 1 1 0.794155400936332 4.03427954644294 0.0810968188684005 0.320068599059702 -14.7252438619274 10.0976333789743 -1.45828664096568 0.146771905538694 -5.10300335215774 31.9070111609315 -0.159933606015912 0.873140271761323 RNA5S10 other 1 1 1 -1.45828664096568 -0.159933606015912 0.554442560088361 0.796567671477126 2.10686294390538 0.378082339803542 0.705922344864864 9.21450880223349 8.7009836814137 1.05901920284217 0.291352001930155 SNORA63 other 1 1 1 0.378082339803542 1.05901920284217 0.343687630320073 -14.6816507112011 10.2831194303242 -1.42774289559508 0.155364665608866 -7.10559296952861 32.4931193397987 -0.218679927132309 0.827185213955386 RNA5S8 other 1 1 1 -1.42774289559508 -0.218679927132309 0.322473099214255 -15.6363814815934 10.7258644081431 -1.45782017062626 0.146900318399393 -5.9559614048863 33.8921272477437 -0.175732888093733 0.860731700952142 RNA5S17 other 1 1 1 -1.45782017062626 -0.175732888093733 0.320156770902951 -14.8628031286806 10.1780009845512 -1.46028705943734 0.146222200629669 -5.40241747953977 32.1609607738635 -0.167980599756528 0.866816119052686 RNA5S4 other 1 1 1 -1.46028705943734 -0.167980599756528 0.194766059129015 2.4719135178824 1.47145631402235 1.67990955241152 0.0950290795897032 -2.02448979591839 7.93604832409743 -0.255100487451811 0.798990329148427 SNORD118 other 1 1 1 1.67990955241152 -0.255100487451811 0.316579269753363 -14.4432549149881 10.1007116966946 -1.42992447945174 0.15473841500933 -1.45903421616889 31.9167381844995 -0.0457137633468286 0.963596859781259 RNA5S6 other 1 1 1 -1.42992447945174 -0.0457137633468286 0.242957423603025 -27.9600227055587 18.1675472478073 -1.53900921925129 0.125854237628963 -7.37773238132799 36.6453421196205 -0.201327971157836 0.840707808192265 RNU4-1 other 1 1 1 -1.53900921925129 -0.201327971157836 0.313733972282797 -15.702579047504 10.5810616764906 -1.48402679500419 0.1398194960564 -7.07386826925978 33.4345722740615 -0.211573463876721 0.832715967875595 RNA5S14 other 1 1 1 -1.48402679500419 -0.211573463876721 0.33607595092493 -14.8600021139734 10.4005005236349 -1.42877759394409 0.155067400897681 -5.42055235104038 32.8640260378123 -0.164938779710181 0.869205704186344 RNA5S2 other 1 1 1 -1.42877759394409 -0.164938779710181 0.319882837619094 -16.2482786216894 11.0078108231802 -1.47606811950964 0.141941260620183 -7.97879986712167 34.7830357481557 -0.229387679812988 0.818868084459117 RNA5S15 other 1 1 1 -1.47606811950964 -0.229387679812988 0.409821737053387 -685.936408704348 807.372981447764 -0.84959049220887 0.39690675117748 -3133.79503670177 2411.71609478733 -1.29940462041745 0.195798671657327 RN7SK other 1 1 1 -0.84959049220887 -1.29940462041745 0.318851615444587 -14.5827847069127 10.0297532384242 -1.45395249117853 0.147968381097865 -4.30903270618791 31.6925200697172 -0.135963713100407 0.892025260053712 RNA5S16 other 1 1 1 -1.45395249117853 -0.135963713100407 0.00959740821377557 -2.65996134226047 3.19595114480604 -0.832290989986926 0.406559074352711 -16.575960465487 5.47286591681424 -3.02875325605198 0.00288911761019372 RNU6-8 other 1 1 1 -0.832290989986926 -3.02875325605198 0.319190442278261 -14.5371757315858 10.1898514046631 -1.42663275000588 0.155684091510988 -1.64205901005647 32.1984063289339 -0.0509981454759421 0.959392239475911 RNA5S7 other 1 1 1 -1.42663275000588 -0.0509981454759421 0.314776155953377 -15.2815435025519 10.4619749067104 -1.46067483805091 0.146115825312453 -4.34900945248091 33.0582758935245 -0.131555846000209 0.895505125220842 RNA5S13 other 1 1 1 -1.46067483805091 -0.131555846000209 0.183913368206036 -76.4552151005167 41.7756272454608 -1.83013924964643 0.0691625642467224 -60.2946442273263 84.2646578423743 -0.715538943267456 0.475359562067326 RNU4-2 other 1 1 1 -1.83013924964643 -0.715538943267456 2.16444453889645e-07 47.372492836676 11.8093661012717 4.01143401182004 9.4131562025951e-05 -51.6775462359991 28.7914655921101 -1.79489113086902 0.0746451186434274 ZNF525 other 0.00209410009138231 1 0.863657081588101 4.01143401182004 -1.79489113086902 0.0077116581095085 871.762832863487 276.170700080803 3.15660869385646 0.00194434192137068 608.920575847918 568.305882523873 1.07146625536177 0.28575233035694 INF2 other 1 1 1 3.15660869385646 1.07146625536177 0.00194745583530966 91.5768947755702 25.4188815637714 3.60271141536344 0.000435633753227018 70.6662771068693 40.4568218268421 1.74670856275675 0.0828654667685501 GP1BB other 1 1 1 3.60271141536344 1.74670856275675 0.000663255076816234 73.9058295798294 27.9364731991334 2.6454960528848 0.00902632811488225 -134.079822050633 87.2735378028259 -1.53631702605611 0.126567322296801 EFCAB2 other 1 1 1 2.6454960528848 -1.53631702605611 1.11814852577202e-06 333.505022770385 79.6340155207364 4.18797194376744 4.78223301339239e-05 -310.388484164064 246.296021445177 -1.26022532699804 0.209545080840561 COX20 other 0.0101606156536904 1 0.453546978990135 4.18797194376744 -1.26022532699804 1.46874864133079e-10 213.498237266284 31.4733190195053 6.78346751843903 2.33235687679369e-10 76.5614265350401 97.3351256791665 0.786575514243438 0.432731341914002 CHML other 1.72636715302021e-06 1 3.00454212868564e-06 6.78346751843903 0.786575514243438 6.9491859915115e-05 30.4913559787975 7.43809346224478 4.0993510142847 6.62717972155306e-05 -6.09286176148305 23.9356435858565 -0.254551825173538 0.799402381202874 STUM other 0.520355047044381 1 0.618050287231163 4.0993510142847 -0.254551825173538 0.82853600679957 6.10311292501241 10.6361978370345 0.573805886137413 0.566920263194675 -0.14567844455145 33.8479532244745 -0.00430390705119841 0.996571453463018 CAPN8 other 1 1 1 0.573805886137413 -0.00430390705119841 9.39817638749046e-09 35.9323543064523 8.06093090632668 4.45759363577357 1.56982175494857e-05 -62.5200869308352 23.8723061898505 -2.61893787862926 0.00968480700582334 TATDN3 other 0.000100372523818398 1 0.15627575570513 4.45759363577357 -2.61893787862926 0.783347903800306 -6.28274266845392 13.7625731048014 -0.456509303936923 0.648666978555761 -28.4935757020957 43.3948738630201 -0.656611557209229 0.512410693887861 SERTAD4-AS1 other 1 1 1 -0.456509303936923 -0.656611557209229 0.436759285562726 2.63928517795464 9.08577785260631 0.290485330014705 0.771840917954871 -35.5016143565101 32.2228591392273 -1.10175246098169 0.272310826452265 CR1 other 1 1 1 0.290485330014705 -1.10175246098169 0.121497895164532 8.45264658123151 7.37773112624867 1.14569729319065 0.253697666114568 -41.5066218073777 27.2502356582406 -1.52316560957248 0.129768117014983 C1orf53 other 1 1 1 1.14569729319065 -1.52316560957248 1.15960828543943e-05 73.8531556255145 15.0198289891329 4.9170437079509 2.20652477730835e-06 100.884051147133 30.8672160716494 3.26832361275988 0.00133086166725238 SAMD5 other 0.0952154363174315 1 0.0235943694437582 4.9170437079509 3.26832361275988 0.0408185333535693 100.240519041201 92.3262191674744 1.08572104376299 0.279355868498532 -199.81858664341 178.594513074465 -1.11883944922819 0.265009132454715 CENPW essential 1 1 1 1.08572104376299 -1.11883944922819 0.770110299937891 -0.44681563544275 10.5273420410052 -0.0424433473997854 0.966204895098907 -12.9503259128 20.0467777476305 -0.646005361850767 0.519318503195401 SPRN other 1 1 1 -0.0424433473997854 -0.646005361850767 9.92131476918902e-07 76.139881067867 19.6123719820401 3.88223724991508 0.000153539295204573 -26.3099996119669 40.9791447383701 -0.642033887723672 0.52181196746478 FAM229B other 0.00905220759540806 1 1 3.88223724991508 -0.642033887723672 0.00177856373015896 18.9126301402902 12.0432699453235 1.57038995440222 0.118350504396838 -50.4114242070989 22.8237135201717 -2.20873015088211 0.0286515399219803 FANK1 other 1 1 1 1.57038995440222 -2.20873015088211 1.20102790088187e-07 106.920417517605 20.406762526303 5.23946007505069 5.21905440467826e-07 -7.82860331250401 37.837440619095 -0.206900973861145 0.836360511347049 EEF1AKMT2 other 0.00118709597723164 1 0.00580829780421156 5.23946007505069 -0.206900973861145 0.000997626619211434 -3.55171748552269 3.97545438219541 -0.893411706955944 0.37305841718811 -28.7408620855965 8.32459125711648 -3.45252531900911 0.000720677898329521 DDO other 1 1 1 -0.893411706955944 -3.45252531900911 8.55116040243344e-07 38.497868344922 15.528881776716 2.47911400823758 0.0142854343951484 -79.7973828012653 32.0945617459069 -2.4863209983368 0.0140108717843699 CCDC162P other 0.00784226920507171 1 1 2.47911400823758 -2.4863209983368 0.930548825084619 1.44908079770464 22.9650303672829 0.0630994505354137 0.949768610044745 -11.9495589954305 40.2778544443595 -0.296678141382577 0.767109419632668 PLPP4 other 1 1 1 0.0630994505354137 -0.296678141382577 0.000601754807748045 114.859486663312 74.3724000425073 1.54438322008788 0.124588710608414 -776.692501258178 257.188081651493 -3.01993971210006 0.00296951987922433 ATP1A1-AS1 other 1 1 1 1.54438322008788 -3.01993971210006 0.0669851585469132 -13.3485753414234 8.14164214108214 -1.63954336362532 0.103168184572705 -32.7779605888842 14.5370704427079 -2.25478446417836 0.0255753809380756 RBM20 other 1 1 1 -1.63954336362532 -2.25478446417836 0.000187571040577545 185.362984360991 219.427366864324 0.844757821277617 0.399582525454104 -1240.03450827487 427.70439494761 -2.89927932217476 0.00429835688229741 SNHG5 other 1 1 1 0.844757821277617 -2.89927932217476 2.90546180033129e-07 288.001770923648 61.1890958533607 4.70674990220223 7.01921757208067e-06 -221.97303953218 210.24332248366 -1.05579115146181 0.293257583981293 PCMTD2 other 0.00277471601931639 1 0.0721926527288497 4.70674990220223 -1.05579115146181 0.120603049587241 98.3809607260789 90.9268248148605 1.0819795030388 0.28150575087159 -347.109123946207 312.420987520051 -1.11103010940944 0.268852963053977 SOX18 other 1 1 1 1.0819795030388 -1.11103010940944 0.989414978327395 9.67423581596488 67.6946509146886 0.14290990034289 0.886609281432319 20.8875763256065 232.321026021978 0.0899082475799264 0.928515182510672 LIME1 other 1 1 1 0.14290990034289 0.0899082475799264 0.146904865161498 9.51514215080347 6.35203129643884 1.49796839888651 0.136188397634461 -15.8340543881335 20.249328487679 -0.781954542234225 0.435441890317463 SAMD13 other 1 1 1 1.49796839888651 -0.781954542234225 4.92179356194833e-10 42.1453653659907 8.06446467787529 5.22605864734156 5.47633724007467e-07 -81.8720221048941 26.2261622832483 -3.12176906482383 0.00214274329859991 EFCAB7 other 5.64382067748615e-06 1 0.00608475830744697 5.22605864734156 -3.12176906482383 0.495816886009074 -33.0426002061364 60.0944070246297 -0.549844849830931 0.583232808783099 -216.89048160558 184.106661286024 -1.17806971290748 0.240609916616926 LDLRAD1 other 1 1 1 -0.549844849830931 -1.17806971290748 0.0277733883864181 47.6732796399381 27.1849487143882 1.753664505341 0.0821066951554348 -42.6673575743221 42.7073162196963 -0.999064360655007 0.319825285799242 ARRDC1-AS1 other 1 1 1 1.753664505341 -0.999064360655007 0.00277336759851799 22.4080907140669 7.60110175610284 2.94800562248436 0.00370352635718606 -19.1307835325364 23.6059945181492 -0.810420569988183 0.418965522642543 ZYG11A other 1 1 1 2.94800562248436 -0.810420569988183 0.709754500890622 1.75844712708107 2.12207307539716 0.828645887584228 0.408595624108941 2.27630643697952 10.2334039339942 0.222438833809529 0.824268943249902 LINC01270 other 1 1 1 0.828645887584228 0.222438833809529 0.379367066449187 8.75075812274369 11.8375906078285 0.739234732189214 0.461139417168116 -12.4107478081485 18.3461156326666 -0.676478228778319 0.499976992496371 LCN8 other 1 1 1 0.739234732189214 -0.676478228778319 0.190279018979165 45.4092418772563 24.7732681185721 1.83299359858031 0.0691641371313365 32.4907478081486 38.394066542714 0.846243983350972 0.399020959305231 LCN6 other 1 1 1 1.83299359858031 0.846243983350972 0.931953452421672 8.55776296094708 31.2184589339721 0.274125093075446 0.784351136423355 -21.9455708259627 140.299274733775 -0.1564197025794 0.875904451660071 SLC12A5-AS1 other 1 1 1 0.274125093075446 -0.1564197025794 0.027412763342501 19.1658230281285 11.0426954004887 1.73561094760254 0.0848811190387285 -32.1008247215076 31.2154021175812 -1.02836492705079 0.305590394457077 LRRC73 other 1 1 1 1.73561094760254 -1.02836492705079 1.21565458692231e-05 131.874785187569 29.2903603783623 4.50232716443424 1.33017119764275e-05 -199.628309835679 196.684080952816 -1.01496932984409 0.311733322470773 FOXO6 other 0.0995377975771989 1 0.133416171123567 4.50232716443424 -1.01496932984409 8.01449523623415e-07 164.55940634355 37.7493216669945 4.35926790407548 2.35885992892162e-05 -289.354303647496 165.782280337368 -1.74538740243323 0.0828864130288377 SYS1 essential 0.00737012981924093 1 0.230790855445691 4.35926790407548 -1.74538740243323 1.69537953360963e-13 129.176697998787 17.828272242352 7.24560945911073 1.97865966073732e-11 -132.256787330317 74.2035138343456 -1.78235208140643 0.076675045498378 INPP5B other 2.19924633099842e-09 1 2.62330697820554e-07 7.24560945911073 -1.78235208140643 0.0609437765896957 5.98672463065686 12.322991062392 0.485817493524561 0.627867055712746 -47.8931586926777 25.8520909144205 -1.85258356282363 0.0660783104629786 NEU4 other 1 1 1 0.485817493524561 -1.85258356282363 0.602638042538102 -8.40618747720864 72.4976004125495 -0.115951251205185 0.907843225992908 276.587692065087 314.247891641512 0.880157669858333 0.3801542942467 MAFB other 1 1 1 -0.115951251205185 0.880157669858333 2.90441411040487e-07 131.251427117782 35.9548322726933 3.65045304960199 0.000363894061287946 -184.011427117782 81.2581436982792 -2.26452905201769 0.0250141545585239 TRAF3IP1 other 0.00277400591684769 1 1 3.65045304960199 -2.26452905201769 2.11017959955314e-12 423.849352310891 67.7455805386627 6.25648712345151 3.58061002343364e-09 -254.077154077155 149.834020315817 -1.69572406548004 0.0919202802507524 GIGYF2 other 2.65228473867835e-08 1 4.43458551402257e-05 6.25648712345151 -1.69572406548004 0.382536917508222 -6.63462317666128 9.08137668854655 -0.730574603851515 0.466120958479769 15.0556624797407 21.1837353432398 0.710718021906616 0.478306786420758 C2orf72 other 1 1 1 -0.730574603851515 0.710718021906616 6.10484663496154e-07 84.5197208960707 20.5074753139979 4.12141034437231 6.13302102477568e-05 -83.5843554902679 44.1282702919454 -1.89412263243693 0.0600836650663202 RUFY2 other 0.00567047047877844 1 0.574234758549747 4.12141034437231 -1.89412263243693 0.271512756047662 -15.4444424065044 23.3410688105229 -0.661685312351315 0.509149104326333 -55.6696074141424 34.5115222364972 -1.61307307839553 0.108749739899837 GGTA1P other 1 1 1 -0.661685312351315 -1.61307307839553 1.85190999017578e-16 761.4996463292 114.901934243499 6.62738753131375 5.86260656331822e-10 -523.437753938987 264.142618319109 -1.98164823711494 0.0493585530490839 PHACTR4 other 2.53878340553197e-12 1 7.45547676657178e-06 6.62738753131375 -1.98164823711494 0.217986761810433 -6.20130436779496 4.18256423049216 -1.48265609947734 0.140222655001014 -17.8790129977495 12.1192765591255 -1.47525414660887 0.142199127062444 CLPSL1 other 1 1 1 -1.48265609947734 -1.47525414660887 9.9600455129274e-05 24.224552820205 8.93270784475911 2.7118935535788 0.00744073959930682 -39.6729101538018 18.8502028454445 -2.1046410205283 0.0369254084266325 TIMM23B other 0.730668938828354 1 1 2.7118935535788 -2.1046410205283 2.44193716344759e-08 139.417344648618 37.4660090434146 3.72116881963769 0.000278018973748476 -147.26220367513 79.0014544740776 -1.86404420849556 0.0642316310699892 ZDHHC18 other 0.00025391262625528 1 1 3.72116881963769 -1.86404420849556 0.138530780545198 -10.148386570149 6.67040227942115 -1.52140547826595 0.130156899114151 8.07457730252782 14.1371063584502 0.571161954773112 0.568701392317425 C10orf128 other 1 1 1 -1.52140547826595 0.571161954773112 0.443584641582795 10.3875105130361 9.25094712229479 1.12285913817432 0.263211487113518 -2.51513877207747 20.9688134772015 -0.119946642417897 0.904678770196406 AGAP9 other 1 1 1 1.12285913817432 -0.119946642417897 0.00121842528694903 34.0671555384022 10.0579169169119 3.38709852346463 0.000892805808129313 -4.21505437373711 25.0651642933379 -0.168163843827564 0.866670819406041 GPRIN2 other 1 1 1 3.38709852346463 -0.168163843827564 3.98122179088922e-07 82.7892152031796 25.4934699119203 3.24746750792323 0.00143102487984207 -102.791048257285 55.5119598982817 -1.8516919317141 0.0659974566431968 TMEM57 other 0.00376106022585305 1 1 3.24746750792323 -1.8516919317141 0.503471653399059 7.66546446090489 8.84976835500368 0.86617684818505 0.387706587491578 -8.88201891857704 22.0273124997458 -0.403227534847002 0.687325973993244 PTPN20 other 1 1 1 0.86617684818505 -0.403227534847002 0.367005807154583 30.5330980246455 22.6431533719005 1.34844725569612 0.179494377821709 9.03719734968115 64.4145012416573 0.140297559951248 0.888608224990408 ZDBF2 other 1 1 1 1.34844725569612 0.140297559951248 0.00163234275578917 -1.05191596431029 2.92122039772905 -0.360094693686259 0.719266514452841 -30.2105531198237 8.76826312008972 -3.44544326579408 0.000733716732618107 GGNBP1 other 1 1 1 -0.360094693686259 -3.44544326579408 7.32452225687247e-14 263.976253270551 44.2745709029847 5.9622543569983 1.60346756750447e-08 -403.507123437662 131.90580525005 -3.0590550785293 0.002614118375611 DAXX other 9.59219434760019e-10 1 0.000193378188641039 5.9622543569983 -3.0590550785293 1.70518720886979e-08 533.454524557505 96.4424425617882 5.53132532096265 1.32191829485072e-07 -243.917611677267 285.510850201364 -0.854319937421772 0.394246210913734 BMPR2 ts 0.000179385694373102 1 0.00152602247957568 5.53132532096265 -0.854319937421772 0.00184652070391519 133.49411983885 101.323060890519 1.31750974225988 0.189663380951497 -422.185111132548 222.919461589712 -1.89389077167963 0.0601519825481276 TCEA3 other 1 1 1 1.31750974225988 -1.89389077167963 1.55067058765093e-10 243.743232174642 45.5438708160682 5.3518339088703 3.05766437531259e-07 -265.363337917963 135.764529811792 -1.95458517983917 0.0524198196218086 RING1 other 1.82079740401972e-06 1 0.00345118578041532 5.3518339088703 -1.95458517983917 0.00424691410231497 53.9997798488295 27.0262949792509 1.9980459730158 0.0474722600376146 -122.126645629999 80.3594557208722 -1.51975451469215 0.130623121752781 HSD17B8 other 1 1 1 1.9980459730158 -1.51975451469215 6.12146990756116e-19 246.139090380523 33.2085886555266 7.41191060342036 7.72809475941291e-12 -334.298760944053 98.7417665523614 -3.3855861872471 0.000901312422685058 RXRB other 8.59515589720662e-15 1 1.03262802175275e-07 7.41191060342036 -3.3855861872471 0.00198051522243345 107.962273412573 40.0383802153295 2.69646955825744 0.00786178115086703 -381.019003541251 169.464516003647 -2.24837041126091 0.0261038020038052 OXLD1 other 1 1 1 2.69646955825744 -2.24837041126091 0.31590415052233 12.6968327680272 36.8301043657742 0.344740613328978 0.730775505716924 -129.285165962247 110.358323427415 -1.17150353455017 0.243266378201609 COL11A2 other 1 1 1 0.344740613328978 -1.17150353455017 0.0147691134605796 -309.644525171379 137.989477265236 -2.24397201372244 0.0262235712477972 -1131.90402378996 417.462572217933 -2.71139043142546 0.00744178894068961 HLA-DOA other 1 1 1 -2.24397201372244 -2.71139043142546 2.64727002679039e-13 936.827283535167 169.878725800051 5.51468277810031 1.39708288766425e-07 -1605.51999198327 513.937810643919 -3.1239577216 0.00212325307387965 BRD2 other 3.41762560458639e-09 1 0.00161111598605441 5.51468277810031 -3.1239577216 0.00255200703498634 -667.909267193211 234.045116934684 -2.85376288102437 0.00489985156868284 -2216.04549704252 708.061791862552 -3.12973461145704 0.00208435500153037 HLA-DMA other 1 1 1 -2.85376288102437 -3.12973461145704 0.175870656016888 -14.9797639341994 62.2219908564031 -0.24074710127437 0.81006522585672 -323.281292996773 182.759713639027 -1.76888706246986 0.0788544814297248 PSMB8-AS1 other 1 1 1 -0.24074710127437 -1.76888706246986 0.369256658252685 -469.281012110726 333.258494325318 -1.40815919204336 0.161254270402614 -348.328719723183 1137.08028012559 -0.306336083574249 0.759794329821129 COL5A2 other 1 1 1 -1.40815919204336 -0.306336083574249 0.0518734888872512 -201.502178503129 122.505115416344 -1.6448470565356 0.102002099636791 -852.232385926049 359.82454924139 -2.36846648657739 0.0190789131427804 PSMB8 other 1 1 1 -1.6448470565356 -2.36846648657739 0.101909681347637 -29.0361634331157 136.546519393073 -0.21264667574228 0.831876663730461 -807.417791128972 402.210245071889 -2.00745207518187 0.0464063476303293 TAP2 other 1 1 1 -0.21264667574228 -2.00745207518187 0.616968565472465 -1.48581150319241 3.01588412484994 -0.49266199949454 0.622935366058811 10.2950681836097 12.2001288365798 0.843849136473209 0.400029506831991 LINC01993 other 1 1 1 -0.49266199949454 0.843849136473209 0.0440097823104341 47.055516789014 22.9135298293354 2.05361274057262 0.0416615359121635 135.75444497167 89.9392173877323 1.50940211527998 0.133193218916186 TNRC6C-AS1 other 1 1 1 2.05361274057262 1.50940211527998 0.0111671432815687 -3565.27744438626 1489.36283048096 -2.39382732764649 0.0178535184967597 -12308.1878705904 4469.36725652166 -2.75389941442615 0.0065842352534021 HLA-DRA other 1 1 1 -2.39382732764649 -2.75389941442615 0.546751645039787 11.3193569445831 101.112161669419 0.111948520906824 0.911007223819715 149.554680409524 150.790145272712 0.991806726752912 0.322817928499626 COL15A1 other 1 1 1 0.111948520906824 0.991806726752912 0.0321571252348391 8.92674578942189 12.6018290803878 0.708369057577093 0.479780041499213 -74.7517119031203 38.0079016546761 -1.96674135242411 0.0509986971289936 NOTCH4 other 1 1 1 0.708369057577093 -1.96674135242411 4.27092873897543e-16 951.179725204374 125.700549132326 7.56702919573615 3.17558572241783e-12 -645.477012424195 379.120687868685 -1.70256341338927 0.0906543550751959 PBX2 other 5.82768226433197e-12 1 4.27592617523561e-08 7.56702919573615 -1.70256341338927 0.0251453143795843 16.3411544551605 11.9159669854799 1.37136620763324 0.172242879922773 -54.9859891559905 36.4455335465117 -1.50871681123333 0.133406830518763 AGER other 1 1 1 1.37136620763324 -1.50871681123333 6.90050414888786e-10 508.908713593397 97.9050382629831 5.19798288854569 6.27060779239004e-07 -539.176677839697 299.447066338305 -1.80057425318221 0.0737143665031108 RNF5 other 7.85070357018972e-06 1 0.00693968164383806 5.19798288854569 -1.80057425318221 9.32939152763588e-08 31.2165691096348 8.07360442003661 3.8664972279498 0.000162841381142956 -57.6054278548871 24.3369933139115 -2.3669903308047 0.0191846920718408 FKBPL other 0.000930606804881679 1 1 3.8664972279498 -2.3669903308047 8.03256282784737e-14 882.029632420284 102.863679408425 8.57474316972602 9.2262502054828e-15 -212.530395640231 478.374943089956 -0.444275768850765 0.657458914461597 MRPL38 other 1.05081986913899e-09 1 1.28401724109704e-10 8.57474316972602 -0.444275768850765 0.00464608507534006 13.762673355747 7.95433742368297 1.73020989966688 0.085583176344928 -106.209721054843 36.9180279904809 -2.87690667232358 0.00458231152909305 SMIM5 other 1 1 1 1.73020989966688 -2.87690667232358 1.48664616418646e-05 9.38649612315355 3.14803744365896 2.98169773744611 0.00333005909626966 -27.6292565132906 9.73130356343231 -2.83921432860384 0.00512920144729198 ERICH2 other 0.120537270992238 1 1 2.98169773744611 -2.83921432860384 0.00209106900811449 78.7791989737204 25.8179826733673 3.05133053850042 0.0026810717448781 -72.6450846114663 79.8092879409827 -0.910233463869341 0.364112700770191 SP5 other 1 1 1 3.05133053850042 -0.910233463869341 0.375519078685786 -3.07585026329052 2.48306388365183 -1.23873182786054 0.217659844386955 -8.62911141620759 7.81685896070508 -1.10391033784614 0.271655652410696 CYP21A1P other 1 1 1 -1.23873182786054 -1.10391033784614 0.25726529645599 -11.4471970766548 24.4143287474374 -0.46887207897765 0.639922985271476 -127.207421864186 77.4833296699161 -1.64173922837464 0.102988976979619 STK19 other 1 1 1 -0.46887207897765 -1.64173922837464 2.36884088161538e-08 89.0255256613161 21.3436023854846 4.17106372455011 5.41441629106205e-05 -177.989238073706 65.3817659363831 -2.72230698459399 0.00734527577747602 DXO other 0.000246548958958529 1 0.510146302943867 4.17106372455011 -2.72230698459399 1.03572373348111e-09 233.013403147974 45.5698796453533 5.11332057405894 1.06171163161217e-06 -315.236657853716 137.807107348503 -2.28752104241262 0.0237203210098136 SKIV2L other 1.16871066086009e-05 1 0.0115864590357836 5.11332057405894 -2.28752104241262 0.00293347890062245 16.6074279763971 6.8579418714711 2.42163440397237 0.0166128907103104 -8.43866062131203 10.3855299882082 -0.812540200730569 0.417736031480481 C9orf129 other 1 1 1 2.42163440397237 -0.812540200730569 7.93102186897572e-12 139.991473629221 21.375523874962 6.54914819623195 1.05705370068351e-09 -94.4797235140625 64.053549824157 -1.47501151416952 0.142487283761985 ZBTB12 other 9.78291547538155e-08 1 1.33273330582177e-05 6.54914819623195 -1.47501151416952 0.000587014367104092 299.082574772431 144.396100039603 2.07126490736525 0.0400356711615708 -639.246357240505 356.511166575437 -1.79306124792936 0.0749647403978123 SDHD ts 1 1 1 2.07126490736525 -1.79306124792936 1.33672163816787e-19 1287.46439178789 138.049627167281 9.32609828947824 1.88830521344564e-16 -618.332680546221 419.299524207759 -1.47468013877317 0.142496769990957 EHMT2 other 1.88437649332525e-15 1 2.66043321522356e-12 9.32609828947824 -1.47468013877317 5.99052709188835e-07 18.9755565180719 4.35953375101511 4.35265732571826 2.44040830047014e-05 -32.1084996523542 14.0880119953513 -2.27913630844077 0.0240327922002523 PKP4-AS1 other 0.00557238830087454 1 0.238379082789923 4.35265732571826 -2.27913630844077 0.0228937742213618 46.9513859532579 29.09598941905 1.61367208645317 0.108672707372748 -88.2258883818038 75.6549012376429 -1.1661622305827 0.245375367332692 LAYN other 1 1 1 1.61367208645317 -1.1661622305827 0.505550394800123 25.4675741259539 149.43725008329 0.17042319844456 0.864913268566878 -452.328264892018 453.59492425017 -0.997207509849794 0.320313667746628 SLC44A4 other 1 1 1 0.17042319844456 -0.997207509849794 0.0316810975144044 214.704669284701 101.869033906637 2.10765392632935 0.0367581058332449 -205.795473496401 309.144433955189 -0.665693607558955 0.506650183682825 NEU1 other 1 1 1 2.10765392632935 -0.665693607558955 5.4809519246398e-06 1087.20042441103 218.143034176115 4.98388788125726 1.71933382313988e-06 518.219124539146 655.32492039877 0.790781959312345 0.430336600762828 C6orf48 other 0.0464181818497744 1 0.018510347939924 4.98388788125726 0.790781959312345 3.2244281573022e-07 1601.60187354405 354.83530333983 4.51364860956403 1.2909668463091e-05 -1664.9047591197 1065.96306315294 -1.56187847090611 0.120452394501205 HSPA1B other 0.00306836583448877 1 0.129716348717138 4.51364860956403 -1.56187847090611 0.000420851270482009 1095.2031865036 381.776116742664 2.86870534450383 0.00472466427940212 -1760.23311487458 1146.89613747901 -1.53477987879856 0.126972904317983 HSPA1A other 1 1 1 2.86870534450383 -1.53477987879856 0.0241309768504519 8.41179787617923 5.39238464212014 1.55994025546218 0.120909803586861 -24.4063851458347 16.1992980876208 -1.50663226355996 0.134036401152603 HSPA1L other 1 1 1 1.55994025546218 -1.50663226355996 1.34827134233365e-06 294.181579736552 66.8553833929541 4.40026763450669 2.06539552763721e-05 -255.825432454414 198.839764508611 -1.28659090442312 0.200259419904463 LSM2 essential 0.0121600592365072 1 0.203462113427542 4.40026763450669 -1.28659090442312 2.52983888281361e-15 556.560223295582 73.9523162218923 7.52593362492711 4.6052933329661e-12 -532.87526062998 251.139168985156 -2.12183253923834 0.0355060450059744 VARS essential 3.41098176569759e-11 1 6.18352735817359e-08 7.52593362492711 -2.12183253923834 0.112943734384719 25.8447734241267 16.3918777288024 1.57668168660839 0.116934194812361 -42.3709486277534 57.2864055036439 -0.739633570220395 0.460655696745479 VWA7 other 1 1 1 1.57668168660839 -0.739633570220395 0.299169661250224 -3.28613882402887 12.0300702680233 -0.273160401461962 0.785098283257899 -48.6529056908676 32.7903514820966 -1.48375676050414 0.139930587466963 CARD16 other 1 1 1 -0.273160401461962 -1.48375676050414 1.59555573187615e-10 140.531576391406 23.1113271521552 6.08063636788167 8.95827481399395e-09 -116.218377439279 65.8146478476779 -1.76584364180229 0.0793909140824268 MBD5 other 1.87254420692985e-06 1 0.000109264077906284 6.08063636788167 -1.76584364180229 8.19805729100667e-05 65.3185798393305 19.0855030966413 3.42241855027785 0.000795150369857464 -98.2322493347649 67.124572181179 -1.46343203603029 0.145387287504339 MSH5 other 0.608049909273965 1 1 3.42241855027785 -1.46343203603029 0.64948212940976 1.18051028341659 2.70962429549568 0.435673050828119 0.66368401130063 -5.82548623364542 9.52987043023686 -0.611287034413608 0.541910846792398 MPIG6B other 1 1 1 0.435673050828119 -0.611287034413608 0.910152547357183 -9.40309135689521 29.0045081577622 -0.32419413236555 0.746230968910195 15.6326045361085 102.01015878685 0.153245566147708 0.878405242358787 LY6G6C other 1 1 1 -0.32419413236555 0.153245566147708 5.04942511365254e-11 253.257886297279 42.9820414516723 5.89217909954405 2.31755906725085e-08 -332.85522923054 153.977326970673 -2.16171585634771 0.0321846673801844 ABHD16A other 6.04769645862164e-07 1 0.000277713103028669 5.89217909954405 -2.16171585634771 0.00270564987934204 4.14450634796245 2.53216127539915 1.6367465959723 0.103725382249793 -20.982348757182 9.07112392702425 -2.31309250385968 0.0220409305728911 LY6G5C other 1 1 1 1.6367465959723 -2.31309250385968 3.94200741678417e-09 717.560077967412 147.357404818986 4.86952168334439 2.7490863590152e-06 -1305.15181043785 527.887893107045 -2.47240337859613 0.01450835600826 CSNK2B essential 4.30546050061167e-05 1 0.0292035443918185 4.86952168334439 -2.47240337859613 1.22256778105754e-11 92.9674573238426 17.2533901482304 5.38835883992213 2.61615563844376e-07 -199.952218404757 61.6839705082481 -3.24155881596533 0.00145719458959506 GPANK1 other 1.49862358602033e-07 1 0.00296515080061215 5.38835883992213 -3.24155881596533 4.17037954875785e-11 63.1717414923565 11.8362614528486 5.33713637063609 3.32229295348243e-07 -127.558490535295 42.3167618718872 -3.01437267155448 0.00301230888051395 C6orf47 other 5.01237917965206e-07 1 0.00374090186562121 5.33713637063609 -3.01437267155448 0.252261223557344 -6.40272955765713 4.07186346850956 -1.5724322800049 0.117916001746619 -1.16561533220535 8.16347301658589 -0.142784245116894 0.886648444370901 FAM155A other 1 1 1 -1.5724322800049 -0.142784245116894 1.39354180442843e-11 21.6527541387393 4.02976488478892 5.37320532532098 2.8510338432505e-07 -46.1679193354646 14.4095405822053 -3.20398274130117 0.00165164640674002 APOM other 1.70388356427464e-07 1 0.00322366396656334 5.37320532532098 -3.20398274130117 9.27501503708107e-17 1282.11179594781 175.712571038506 7.29664239940375 1.55933233838588e-11 -2182.44374607754 634.592884307435 -3.43912420080058 0.000754559682228219 BAG6 other 1.27661306970384e-12 1 2.07126114507796e-07 7.29664239940375 -3.43912420080058 4.09842141214436e-11 1861.62450003279 351.245230345288 5.30007054673094 4.0327798163478e-07 -3883.07858735258 1268.53601029604 -3.0610708374344 0.00261116363347716 PRRC2A other 4.92835174810359e-07 1 0.00451953634018098 5.30007054673094 -3.0610708374344 0.171977773793583 -39.7895610456646 22.3521634550826 -1.7801212453382 0.077002729363674 -93.6322170420015 73.0584413485389 -1.28160709855979 0.201882117690464 AIF1 other 1 1 1 -1.7801212453382 -1.28160709855979 0.456495137471378 -17.7486463973345 14.1699836241802 -1.25255235772098 0.212231181772042 -26.6782590587257 46.4269805316186 -0.574628346561474 0.566365146752907 LST1 other 1 1 1 -1.25255235772098 -0.574628346561474 7.40260526920662e-09 67.8090434621176 16.3346955302162 4.15122787790462 5.39247215174925e-05 -157.497222491783 53.5986711028811 -2.93845386930343 0.00379290481100469 NFKBIL1 other 7.94965779860099e-05 1 0.508240500302366 4.15122787790462 -2.93845386930343 2.78997433487075e-10 228.47900382545 47.2187462763372 4.83873507543652 3.16187598806456e-06 -155.710312168437 92.7529398494933 -1.67876417093736 0.09523922114317 ZNF814 other 3.23860220791797e-06 1 0.0334305148218065 4.83873507543652 -1.67876417093736 0.432937135047567 9.86962783051754 20.4014578889099 0.483770713066668 0.629218407033323 -57.8533334795366 65.0276961111628 -0.889672200298135 0.374994516751488 MICB other 1 1 1 0.483770713066668 -0.889672200298135 1.66138367194555e-07 56.7898770987532 13.1291942701713 4.32546551830496 2.7343169297538e-05 -25.6781080979451 26.1280676947212 -0.982778688342612 0.327267903822701 ZNF551 other 0.00162416867769397 1 0.265967007757152 4.32546551830496 -0.982778688342612 0.182373034568523 9.85119280979379 13.4203221186501 0.734050399289872 0.464005929491543 -52.3452908740343 41.9232055983507 -1.24859943620565 0.213658533328582 MICA other 1 1 1 0.734050399289872 -1.24859943620565 6.68267094550138e-14 21.3354559750819 3.14594675245698 6.78188718814739 2.35211631261042e-10 -4.33447652825641 6.26069479569964 -0.692331549404657 0.489765030005242 ZNF805 other 8.76298641083596e-10 1 3.02929059901097e-06 6.78188718814739 -0.692331549404657 0.313954142078866 -1534.29225165987 1688.92185325786 -0.908444786062944 0.365026844186608 -7843.84310091102 5225.9898979333 -1.50092963325723 0.135369499887115 HLA-C other 1 1 1 -0.908444786062944 -1.50092963325723 0.305737001727771 1.4788798385353 9.32236766598483 0.158637793693912 0.874156835442948 -38.4338222927028 28.9997400100631 -1.32531609867419 0.186979577018289 PSORS1C3 other 1 1 1 0.158637793693912 -1.32531609867419 0.102895151108619 -5.5622552199716 14.8584225497829 -0.374350318907365 0.708645627142256 -95.8948997653313 46.2211324785636 -2.07469818723731 0.0396360437328277 POU5F1 og 1 1 1 -0.374350318907365 -2.07469818723731 1.99772057844819e-09 132.487782378307 24.508761851806 5.40573135352181 2.34077795524336e-07 -144.960120805593 83.5793099779242 -1.73440198111089 0.0847970877790191 CCHCR1 other 2.22086596706086e-05 1 0.00266169861290722 5.40573135352181 -1.73440198111089 0.579609040438887 -0.390613491229199 1.66200427972359 -0.235025562806711 0.814493214315834 -5.85741936560377 5.6677351438469 -1.03346737575816 0.302964490737224 PSORS1C2 other 1 1 1 -0.235025562806711 -1.03346737575816 0.0113322842424948 44.972747230744 18.9541783423045 2.37270887814577 0.0188611496599734 -56.2976089169211 64.6371757425841 -0.870978786900048 0.385087180000836 CDSN other 1 1 1 2.37270887814577 -0.870978786900048 0.0249251392153778 40.4545942119152 21.8489435135214 1.85155836880074 0.0659557098538665 -88.929735862909 74.5088484538112 -1.1935459708257 0.234444640684877 PSORS1C1 other 1 1 1 1.85155836880074 -1.1935459708257 0.294606203002911 -107.268899356618 78.9047802237906 -1.35947276010884 0.17594619631926 -328.818275669643 269.715223875476 -1.21913131541086 0.224622853285944 C6orf15 other 1 1 1 -1.35947276010884 -1.21913131541086 0.698094503291388 -0.927068289663708 4.76472111798742 -0.19456926579898 0.845983320411274 -13.6258560333295 16.1715468910447 -0.842582105789469 0.400752157721317 MUC21 other 1 1 1 -0.19456926579898 -0.842582105789469 4.75345963821421e-14 204.226324824017 29.3156394516916 6.96646324773353 1.11787677555896e-10 -192.496008573842 91.9865685365832 -2.09265343447708 0.0381592866377799 DHX16 essential 6.25745426774519e-10 1 1.45424589732466e-06 6.96646324773353 -2.09265343447708 3.68573747672962e-08 71.8459654801763 16.3560311063731 4.3926283224163 2.16617444895283e-05 -118.280085002286 50.7432520434411 -2.33095200325408 0.0211534726369525 C6orf136 other 0.000378598953609667 1 0.212761654376147 4.3926283224163 -2.33095200325408 1.3758642541422e-09 205.628530127628 51.5643528698216 3.98780395143818 0.000106000379217558 -577.724044033162 159.615892820593 -3.61946441437708 0.000408848909778899 MRPS18B essential 1.54220624246799e-05 1 0.966511457705698 3.98780395143818 -3.61946441437708 0.0444117041463242 102.388294174892 57.4697819018711 1.78160227490891 0.0769515865629868 -169.309982302614 177.900361815898 -0.951712411230655 0.342859973274486 PPP1R10 essential 1 1 1 1.78160227490891 -0.951712411230655 5.31626686829568e-15 454.004448769637 66.2979450331413 6.84794149415471 2.08839245525716e-10 -597.65812232363 205.228348163652 -2.9121616368858 0.00416996956639132 ABCF1 essential 7.12645573695036e-11 1 2.69465278501831e-06 6.84794149415471 -2.9121616368858 7.23410607851664e-13 135.739673101832 22.1139814645652 6.13818336238263 7.38624073240084e-09 -172.467027693826 67.6265908795918 -2.5502842217923 0.0117869083505734 PRR3 other 9.2205916076773e-09 1 9.04297452867834e-05 6.13818336238263 -2.5502842217923 0.000590665553725066 24.3294031327852 17.5783481656638 1.384055140079 0.168357166698206 -146.829488448281 48.8733679387498 -3.00428422760417 0.00311124414745465 LINC01123 other 1 1 1 1.384055140079 -3.00428422760417 1.68595017106298e-14 318.311762512192 47.6632499829284 6.6783478387689 4.56403570549013e-10 -383.046950601465 141.236724246448 -2.71209172150635 0.00747807660682155 GNL1 other 2.23944761222295e-10 1 5.82051473521157e-06 6.6783478387689 -2.71209172150635 0.139702788090258 -352.233595847184 520.530642489695 -0.676681768747471 0.499636343662451 -3115.00874651117 1562.80651264724 -1.99321459265911 0.0480276259763183 HLA-E other 1 1 1 -0.676681768747471 -1.99321459265911 0.00352215271815022 2.68536392036181 2.89626029789445 0.927183210125845 0.355340972190248 -12.86909591085 5.58336452579289 -2.30489982364576 0.0225624131160945 LINC01257 other 1 1 1 0.927183210125845 -2.30489982364576 3.09089255742509e-08 58.6964089410041 17.3853649710119 3.37619653305372 0.000931794096653846 -142.644924880909 48.8395733568334 -2.92068327130361 0.0040214307476239 ZNF468 other 0.000319227383330864 1 1 3.37619653305372 -2.92068327130361 0.0784311343527407 -7.14696991807208 3.76792246509649 -1.8967932552426 0.059727506544864 -21.5748712710292 11.213696100144 -1.92397502824713 0.0562020726763341 TRIM15 other 1 1 1 -1.8967932552426 -1.92397502824713 2.23834037155118e-09 58.857839930349 11.3063893704269 5.20571492825979 6.01266753273727e-07 -13.4407990201625 21.9263341549371 -0.612998001635217 0.540770306685565 ZNF616 other 2.47918579553009e-05 1 0.00666564322679254 5.20571492825979 -0.612998001635217 0.549922006291564 -12.5518983276931 14.6458973624767 -0.857024873044072 0.392754249268084 -42.3954170063155 43.5808012677634 -0.972800310527452 0.332168236519632 TRIM31 other 1 1 1 -0.857024873044072 -0.972800310527452 0.0790814761293058 -6.41246943161332 18.9367527026592 -0.338625609802299 0.735350063928627 -123.335478266598 56.3488078446984 -2.18878593858666 0.0301086040773727 RNF39 other 1 1 1 -0.338625609802299 -2.18878593858666 6.08463392204762e-13 367.064397264469 63.3809950774792 5.79139530415633 3.73066072824705e-08 -560.603450035727 188.453776469161 -2.97475306963385 0.00339901685961565 PPP1R11 essential 7.77555368898465e-09 1 0.000442978654872054 5.79139530415633 -2.97475306963385 0.45915241157714 -56.6277181208053 46.2225923329688 -1.22510909195404 0.222392563457083 -37.1399328859059 138.722829839268 -0.267727618654683 0.789264922401871 HLA-J other 1 1 1 -1.22510909195404 -0.267727618654683 0.20180342860356 34.7872246606104 33.1192179531795 1.05036371057399 0.29517534841652 -89.0091966928654 98.4749717064578 -0.90387633680354 0.367454655372726 ZNRD1ASP other 1 1 1 1.05036371057399 -0.90387633680354 0.00126600317247179 33.8421052631579 9.18709989567035 3.68365486905251 0.000317776831140374 33.1491228070175 21.0565432156896 1.57429082577607 0.11747239303403 DISP3 other 1 1 1 3.68365486905251 1.57429082577607 1.79023100817398e-06 12640.7482660763 3078.98242999833 4.10549542047344 6.77732539963954e-05 -6091.10066766365 5036.52742022543 -1.20938499077823 0.228524647675503 RACK1 other 0.0159634898998874 1 0.631307860976424 4.10549542047344 -1.20938499077823 0.346864677466593 -50.784718000018 35.2506347967843 -1.44067527557407 0.15168050872687 -83.4452807320728 104.015285251577 -0.802240560416167 0.423634242716735 HLA-G other 1 1 1 -1.44067527557407 -0.802240560416167 0.0058510517591065 -55.2207670329458 53.608017464448 -1.03008411138441 0.304585612529506 -496.178378708455 152.232359181473 -3.25934894116022 0.00137438654636502 TBC1D8 other 1 1 1 -1.03008411138441 -3.25934894116022 0.666341338109429 -68.9547347859183 97.3599178011737 -0.708245614244829 0.479856467093417 -228.09511224739 285.255534442307 -0.799616781119885 0.425156574666514 HLA-F other 1 1 1 -0.708245614244829 -0.799616781119885 0.0706791291919569 2.41340159589425 8.59341987266879 0.280842974235441 0.779205365570087 55.4347260089938 24.9917503996382 2.21812098482691 0.0280006210240065 ZFP57 other 1 1 1 0.280842974235441 2.21812098482691 1.42058477210206e-08 101.00327997791 16.0263733091131 6.30231668948312 2.86488654985886e-09 -30.2620635412039 65.8771995243018 -0.459370825713992 0.646607379225458 LINC02210 other 0.000150127398715745 1 3.5601945155096e-05 6.30231668948312 -0.459370825713992 2.34976889491729e-14 537.116593081572 97.1023133932481 5.53145001712101 1.29996010153713e-07 -372.631857344937 168.847597411557 -2.20691240537268 0.0287715394622103 AKT1S1 other 3.11344378576541e-10 1 0.00150184390530585 5.53145001712101 -2.20691240537268 0.00119142211687185 243.78622880525 74.2963982563846 3.28126577501084 0.00127839562490774 -54.1847249639399 214.049770019176 -0.253140776367504 0.800497034386837 GABBR1 other 1 1 1 3.28126577501084 -0.253140776367504 5.46175145013384e-05 152.904720950542 35.9288749946785 4.25576144460936 3.59413243976142e-05 3.43082113842666 139.424133600417 0.0246070823596382 0.980400021041373 CASC10 other 0.41378228986214 1 0.345000772892698 4.25576144460936 0.0246070823596382 0.0651665488715357 1.36217541064125 1.36224212599008 0.999951025337156 0.318902817570666 -4.29012941178352 2.51795590451725 -1.70381435357424 0.0904327473296949 MAMDC2-AS1 other 1 1 1 0.999951025337156 -1.70381435357424 0.105448479330559 0.936993147846842 13.1417833096263 0.0712987823471795 0.943252473107154 -48.5999833615706 24.2911522474829 -2.00072779036682 0.0471790906602442 C9orf135 other 1 1 1 0.0712987823471795 -2.00072779036682 5.63004156102667e-15 514.898858835885 81.7048233739111 6.30193956211765 2.94442624000861e-09 -739.585892648031 232.579043440327 -3.17993350436058 0.00178130356887066 TRIM27 other 7.54481869593184e-11 1 3.65638850484269e-05 6.30193956211765 -3.17993350436058 0.411156280800951 7.01869368259272 7.59422015600643 0.924215197664698 0.356848851183093 -6.94998140489388 12.560896935558 -0.553302956034896 0.580874269306426 RANBP17 other 1 1 1 0.924215197664698 -0.553302956034896 0.515339815799595 11.3468447881877 10.8260428236399 1.04810640166789 0.296210708655505 -15.8342063631571 43.5451535183949 -0.363627294515525 0.716628656694325 TTC25 other 1 1 1 1.04810640166789 -0.363627294515525 0.0161693166655333 336.548271883071 119.708058029816 2.81140866723646 0.00581647746355171 27.0710936498346 505.101138367627 0.0535953922759357 0.957352165360106 MROH6 other 1 1 1 2.81140866723646 0.0535953922759357 2.32799678492242e-12 330.952455144438 66.6660378646105 4.96433365091467 1.80941610157255e-06 -372.37668202814 131.448964337121 -2.83286128503168 0.00523114503714715 ATXN2 other 2.92326556282708e-08 1 0.019454841924108 4.96433365091467 -2.83286128503168 1.96825604813116e-08 75.1914628258056 62.3284712460764 1.20637425116598 0.229523212630577 -575.351133069523 123.027001246799 -4.67662486477532 6.33174350422544e-06 TCTN1 other 0.000206155138481258 0.0920762140384464 1 1.20637425116598 -4.67662486477532 3.56860691620207e-05 32.8143105131823 15.3420173208166 2.13885239646149 0.034034678716518 -73.9201113883764 30.3197696535505 -2.43801691876377 0.0159134814308698 FAM216A other 0.276852524558956 1 1 2.13885239646149 -2.43801691876377 1.27773317736734e-18 117.023313553722 16.6309963485843 7.03645837572948 7.09786429033282e-11 -96.9398270210859 37.5589461405358 -2.5810049797021 0.0108367428601308 ZBTB48 other 1.78972086153843e-14 1 9.28684563747146e-07 7.03645837572948 -2.5810049797021 0.493899050839753 16.2694584944957 13.6789201618698 1.18938178613302 0.236085124940295 20.7870127938114 28.1982120226284 0.737174852686769 0.462116260481707 IGFL2 other 1 1 1 1.18938178613302 0.737174852686769 0.106232888909195 5.78258022265881 2.84383520004395 2.03337388276559 0.0438644572921539 14.9819908316962 12.8003357739107 1.17043733042004 0.243771879563674 GPR20 other 1 1 1 2.03337388276559 1.17043733042004 4.76430474879444e-09 237.806205851785 37.3817438521975 6.36155998478935 2.45752722078942e-09 90.8907678486497 70.4427239586549 1.29027900599069 0.19900761361069 MZT1 other 5.17986334414153e-05 1 3.0610959062153e-05 6.36155998478935 1.29027900599069 1.63372665567276e-10 11.2135137330089 2.85183900335582 3.93202902401352 0.000126071805308191 -54.9173121265781 12.4613083419122 -4.40702618214414 1.93357615974978e-05 ZNF155 other 1.91587124910744e-06 0.279943156408573 1 3.93202902401352 -4.40702618214414 0.00914527099830977 60.9893527833669 19.8228887638947 3.07671366720538 0.00252131754766515 26.0138539570758 61.3134653626552 0.424276360881084 0.672020202529391 ATP6V0E2-AS1 other 1 1 1 3.07671366720538 0.424276360881084 0.214452375419777 6.92990945988137 4.01496814814057 1.72601853967155 0.0863239943208319 5.9921167655323 11.4701787866224 0.522408314377876 0.602127138783319 CD177 other 1 1 1 1.72601853967155 0.522408314377876 7.87383360989838e-10 191.230320699708 28.3222286891269 6.75195171957364 4.11702826301519e-10 16.8040816326528 86.0543039163612 0.195272994700942 0.845477239387985 ZNF783 other 8.93758853059565e-06 1 5.2562099833915e-06 6.75195171957364 0.195272994700942 5.56468597243956e-10 78.5397391508083 11.548226697306 6.80102159486789 2.8869578964445e-10 5.24446151042622 38.6025445289859 0.135857922694403 0.892131578616989 ZNF425 other 6.36433134667913e-06 1 3.70569915587616e-06 6.80102159486789 0.135857922694403 0.829340985392521 -6.90454936966574 32.9610179598499 -0.209476217575448 0.834362634538194 -65.8743637929683 107.665631682337 -0.611842077770256 0.541574719037477 LRRC10B other 1 1 1 -0.209476217575448 -0.611842077770256 2.57832928781915e-10 45.2374859243639 14.378665232441 3.14615335937439 0.00198172644554737 -106.861694551771 29.4944861808653 -3.6231075156379 0.000393311291933925 C12orf73 other 2.9967921312322e-06 1 1 3.14615335937439 -3.6231075156379 0.03399553498134 339.155716441846 168.672084288807 2.01074005738336 0.0462595731429114 -123.168451089519 294.281334019794 -0.418539801376714 0.676189307799316 PCDHGA1 other 1 1 1 2.01074005738336 -0.418539801376714 0.0729018738291044 25.799876926771 61.076731735516 0.422417444314042 0.673359267300067 -179.707181773155 96.910845137348 -1.85435573818867 0.0657625638906802 PCDHA9 other 1 1 1 0.422417444314042 -1.85435573818867 0.0723941148892192 24.2630615216048 61.1470350483136 0.396798659206191 0.692111651381362 -181.685983159981 97.0223958583112 -1.87261901288554 0.0631771347848561 PCDHA8 other 1 1 1 0.396798659206191 -1.87261901288554 0.0910446917889273 30.7550062287057 61.9344875904265 0.496573192501227 0.620257912366839 -168.476770678554 98.2718518981689 -1.71439499128532 0.0886379326057569 PCDHA7 other 1 1 1 0.496573192501227 -1.71439499128532 0.0764413407141152 28.9785792546559 61.6129913019499 0.47033228938097 0.638839217921237 -176.479247152056 97.7617316586036 -1.80519763876876 0.0731624041851578 PCDHA5 other 1 1 1 0.47033228938097 -1.80519763876876 0.107814645260101 38.7936679922842 68.4340182247181 0.566876956792113 0.571692755741116 -173.377616507513 109.281242493666 -1.5865267684668 0.114844202808051 PCDHA4 other 1 1 1 0.566876956792113 -1.5865267684668 0.0706632287190147 28.946407734622 61.5260366382868 0.470474116589025 0.638738156794076 -179.914069011502 98.2499918018002 -1.83118660584159 0.0691687264828374 PCDHA2 other 1 1 1 0.470474116589025 -1.83118660584159 0.0584074006630184 39.9060676779459 62.8401577462182 0.635040857776133 0.526423701253582 -180.623103850642 100.348491804976 -1.79995833122911 0.0739901849593724 PCDHA1 other 1 1 1 0.635040857776133 -1.79995833122911 2.63422413118866e-07 120.620276784326 39.1114058212742 3.08401792907982 0.00243724561407804 -155.953786957171 66.41058272927 -2.34832733802282 0.0201808945788226 TRIM13 other 0.00252701120904928 1 1 3.08401792907982 -2.34832733802282 0.0446075458973736 143.460138635846 56.9362318934474 2.51966338243674 0.0127797824780566 110.115840639945 226.647731287545 0.485845766089946 0.62777616168364 PRSS1 other 1 1 1 2.51966338243674 0.485845766089946 6.8508930374291e-12 191.963489272166 35.3464269261435 5.43091638861474 2.52898079218158e-07 -78.1384712260601 62.4897967368073 -1.25041967339343 0.21330930347395 SPIRE2 other 8.46907397286985e-08 1 0.00286862291257156 5.43091638861474 -1.25041967339343 0.250527862808061 18.6252542109661 14.296161702959 1.30281502111935 0.194689044222234 -48.6436387480372 76.3215006521604 -0.637351707348279 0.524893982402079 AARD other 1 1 1 1.30281502111935 -0.637351707348279 0.716542124613266 70.0627828746174 138.537028271635 0.505733259538687 0.613771756682343 -289.735610444602 638.238061668808 -0.453961660774394 0.650499716395913 PKHD1L1 other 1 1 1 0.505733259538687 -0.453961660774394 0.0287749937460658 4.33038397825678 1.88259152491973 2.30022494042696 0.0227958272693863 12.6121829525954 7.26633589042338 1.73570051574653 0.0846433381367661 SLFN12L other 1 1 1 2.30022494042696 1.73570051574653 0.00466806776770636 53.7591748466505 16.1295553227296 3.33296075254434 0.00107321276381216 37.7770671040044 58.9994707706876 0.640295016388061 0.522920164556347 SLC35B4 other 1 1 1 3.33296075254434 0.640295016388061 0.00505582486110337 12.0259512068518 6.5714944274854 1.83001771355888 0.0691683520663265 -10.2850194653517 11.833546599625 -0.869140910441645 0.386113909407552 SYCE1L other 1 1 1 1.83001771355888 -0.869140910441645 1.01864587141759e-08 330.445612161207 80.8864393099146 4.08530298750217 7.05940428893795e-05 -162.413617872334 142.814336329915 -1.1372360930008 0.257205967941354 TMEM231 other 0.000108485785305973 1 0.656171628656783 4.08530298750217 -1.1372360930008 0.785507482965122 0.697642724213773 1.95110788324151 0.357562352244064 0.721154147167906 4.52753392526312 6.86737173171936 0.659281906111346 0.510686795135342 FAM71F2 other 1 1 1 0.357562352244064 0.659281906111346 0.781223087333733 3.78503536693192 5.60981694905516 0.67471637689879 0.500887722164527 1.73721438875704 8.67646626288101 0.20022141919563 0.841576821334757 CCNI2 other 1 1 1 0.67471637689879 0.20022141919563 0.00228341844001214 9.15021046141835 2.98867760230771 3.06162513291932 0.00267942733561339 0.669249568653882 6.72890172435539 0.0994589601794184 0.920928266334037 TMEM240 other 1 1 1 3.06162513291932 0.0994589601794184 0.13713032511563 -3.0001367215984 5.47381319785634 -0.548088985348152 0.584585388034522 -23.5556639200817 12.2325052301834 -1.92566146319387 0.0563643588559805 TMEM88B other 1 1 1 -0.548088985348152 -1.92566146319387 0.000284793243505447 -12.6465504904283 10.9985763494712 -1.14983522308651 0.251960240750612 -68.321249683506 17.8935575550617 -3.81820381292369 0.000193107033631568 C4orf47 other 1 1 1 -1.14983522308651 -3.81820381292369 0.00444973725105173 100.316333488856 37.5322796745799 2.67280150203077 0.00835463908704347 -150.284129701839 146.393538596313 -1.02657624880737 0.306272653613767 TRIQK other 1 1 1 2.67280150203077 -1.02657624880737 4.8894818971283e-14 71.3729133743191 9.69378201937588 7.36275204369763 1.06021333449518e-11 -60.1722185657261 42.5733078283999 -1.41337898404 0.159588951579808 SDHAF1 other 6.43406922843113e-10 1 1.41273426821482e-07 7.36275204369763 -1.41337898404 3.80004472513069e-06 24.7366996661752 4.74477500076984 5.21346105182262 6.46544638618579e-07 33.3510729627431 11.7220039377385 2.84516821013604 0.0051006411720517 ARID3C other 0.0327373853070009 1 0.00714755097992839 5.21346105182262 2.84516821013604 1.08103313611999e-07 525.006750183101 97.5875189632046 5.37985549546613 2.7222867288543e-07 -110.498811749144 421.471076733761 -0.262174127357606 0.793537563418462 PSENEN other 0.00107292538759909 1 0.00308217303440884 5.37985549546613 -0.262174127357606 0.000166361542424839 30.6969376979937 7.15206789649855 4.29203667278131 3.12859735799784e-05 35.6875345703223 25.1222649640915 1.42055402334671 0.157481141507661 LINC00654 other 1 1 0.302754366333451 4.29203667278131 1.42055402334671 1.36216265363916e-10 509.556102495552 75.938040902549 6.7101560224534 3.61468883672467e-10 46.9269172755758 235.981288866356 0.198858636212264 0.842639072711713 ZBTB10 other 1.6032654433333e-06 1 4.62354849105453e-06 6.7101560224534 0.198858636212264 3.95668611507395e-11 117.735148514852 32.4076133871583 3.63294720621127 0.000379739508909484 -131.68387553041 48.5685339496888 -2.71130019421255 0.0074534574865863 C4orf46 other 4.7618717394915e-07 1 1 3.63294720621127 -2.71130019421255 1.02200404034461e-18 11.5339839796306 1.14935377106462 10.0351904435368 1.3537814310553e-18 3.93678438132591 5.07330938311382 0.775979559699087 0.438935898305125 SCGB2B2 other 1.43233866254297e-14 1 1.92873240482448e-14 10.0351904435368 0.775979559699087 0.00190337025672483 373.340096220515 208.623317413572 1.78954155675902 0.0754928151403649 -614.801615584212 354.991705747156 -1.73187600056804 0.0852980306653115 LGR4 other 1 1 1 1.78954155675902 -1.73187600056804 0.0170877292002255 -263.704662865451 138.877477749657 -1.89882958085407 0.0595597776314806 -639.265421705188 221.501452478687 -2.88605521341535 0.00449340793932904 PSMB10 other 1 1 1 -1.89882958085407 -2.88605521341535 0.00115854863598617 22.1059876858549 6.28319565470451 3.51827141803282 0.000572172835937395 -2.79104490988449 19.4974323086395 -0.143149357602732 0.886360578602027 SPDYE2 other 1 1 1 3.51827141803282 -0.143149357602732 6.48242900517465e-14 554.755900538529 105.364284600318 5.26512283211434 5.24478782431665e-07 -220.68270061831 166.027331743246 -1.32919500844346 0.185976950695192 E2F4 other 8.50300212608758e-10 1 0.00583587541211714 5.26512283211434 -1.32919500844346 0.056791247596757 117.727214409079 70.9983152853871 1.65816912606812 0.0994451224303712 -260.616580310882 266.11118981022 -0.979352204229906 0.329037165111773 PDE7A other 1 1 1 1.65816912606812 -0.979352204229906 3.30301741290891e-09 61.3349367088608 10.6802474116428 5.74283856402035 4.81862467940672e-08 -9.59084712755594 29.7885606808577 -0.321964099921051 0.747916515791986 TMEM170B other 3.62737372285656e-05 1 0.000569127760884728 5.74283856402035 -0.321964099921051 0.129505220296405 -12.6693334595721 7.32149098726793 -1.73043079361895 0.0856237497100849 -36.5589775660511 23.7178589940517 -1.54141137171023 0.125337808854504 MUC12 other 1 1 1 -1.73043079361895 -1.54141137171023 1.35221800228384e-06 355.439076085647 92.9115677426048 3.82556321803039 0.000188743747136643 -128.764360895011 135.634773012563 -0.949346233528809 0.343922401035353 SNX2 other 0.0121929497265934 1 1 3.82556321803039 -0.949346233528809 0.250624658175521 96.3472385231884 68.0881786856165 1.41503621308557 0.159116839702897 -83.9909124442507 225.478521824939 -0.372500723192877 0.710042380427354 SAP25 other 1 1 1 1.41503621308557 -0.372500723192877 0.0182134071778119 39.1724414695459 13.8333245214433 2.83174456066753 0.00524441204276536 45.398870278947 43.2850840506986 1.04883405622529 0.295887135840121 NT5M other 1 1 1 2.83174456066753 1.04883405622529 2.66725124386114e-05 109.870348018507 37.8575434096818 2.9022049008708 0.00431028519584041 -263.815328907665 101.986815961324 -2.58675914549298 0.010715606998466 SARNP essential 0.210739520777468 1 1 2.9022049008708 -2.58675914549298 0.00365367994561919 10.1404310217203 3.03238020500529 3.34404999906751 0.00105263765606509 0.16508198355796 11.6162500751068 0.0142112973197543 0.988681077406951 LINC01460 other 1 1 1 3.34404999906751 0.0142112973197543 5.27792573172252e-06 2915.37277671615 780.134096806038 3.73701494224139 0.000264748137830854 -44.8524033514575 1193.57114524681 -0.0375783241158891 0.970074190741312 ADGRG1 other 0.0447620881307387 1 1 3.73701494224139 -0.0375783241158891 1.97352785798432e-12 497.963432865972 184.434432458777 2.69994830264285 0.00771595658222475 -1203.99695514393 291.935980078488 -4.12418145519519 6.08507686742793e-05 IPO7 essential 2.48329010370167e-08 0.874912351998787 1 2.69994830264285 -4.12418145519519 0.00100076246570664 96.0819272150042 105.279611442459 0.912635655646561 0.362992000397005 -887.432153565757 279.346652443711 -3.17681327412569 0.00182966874112977 PRR13 other 1 1 1 0.912635655646561 -3.17681327412569 1.31186951313613e-10 152.297214873603 21.9862279918631 6.92693694116002 1.1596371517528e-10 -3.47630070546754 70.5259533229301 -0.049291084227532 0.960752462662441 TECPR1 other 1.54511991257174e-06 1 1.50752829727864e-06 6.92693694116002 -0.049291084227532 0.793121213822931 31.1229764532749 258.04972806214 0.120608445073735 0.90415942016773 -158.597344861417 403.575743892687 -0.392980369265177 0.694880981867275 MT1H other 1 1 1 0.120608445073735 -0.392980369265177 0.0574111309504481 -3.75873804267834 33.4889178878602 -0.112238265066214 0.910781609122735 -94.0472467500612 52.3748467020269 -1.7956567450234 0.074522624363882 MT1A other 1 1 1 -0.112238265066214 -1.7956567450234 0.392200591592127 17.327246007993 19.7504123765797 0.87731059370385 0.381720918283361 -21.6801017939389 34.3397502104221 -0.631341278288013 0.528778302565001 C15orf59 other 1 1 1 0.87731059370385 -0.631341278288013 0.414415133808461 -39.1391648270785 63.5558041204619 -0.615823611528779 0.538925980367145 -126.514747363257 99.3978219594818 -1.27281206840557 0.205015448137163 MT1M other 1 1 1 -0.615823611528779 -1.27281206840557 5.04813811082996e-06 958.528199566161 318.356650142246 3.01086281419872 0.00304240242132406 -525.62644354922 484.536082553323 -1.08480351097769 0.279693084661199 CFI other 0.0429243183563872 1 1 3.01086281419872 -1.08480351097769 0.645951941776545 8.03343867876451 79.7632455435665 0.100716045642559 0.919911268649661 -211.184320521969 246.117136081961 -0.858064269249587 0.392235140845859 SAMD9 other 1 1 1 0.100716045642559 -0.858064269249587 0.189688334964169 -266.71723758718 187.101504936449 -1.42552160485173 0.156004308679526 -905.83019013534 580.726053287421 -1.55982357775675 0.120827970873895 KRT6A other 1 1 1 -1.42552160485173 -1.55982357775675 0.00392472738027334 15.8919908315881 17.6013449590703 0.902885027737537 0.368074134134581 -46.3323054598222 26.1823314733614 -1.76960197402443 0.078881057924205 CNEP1R1 other 1 1 1 0.902885027737537 -1.76960197402443 0.426094378598774 -30.3918702177752 47.9997968647796 -0.633166642421262 0.52756396587182 -170.901964390819 131.671036659247 -1.29794652436054 0.19624634141104 KRT81 other 1 1 1 -0.633166642421262 -1.29794652436054 0.131323792317911 12.2035405534149 6.06973214944418 2.01055668569038 0.0462264238313106 11.8210197661641 10.4646724204522 1.12961202140079 0.260504981707568 EXOC3L4 other 1 1 1 2.01055668569038 1.12961202140079 4.25668570659627e-06 37.727592034196 13.5364265349893 2.78711607798977 0.00598775323962516 -21.884041883429 19.073141023637 -1.14737482705699 0.253006118228849 ATP6AP1L other 0.0364993653695014 1 1 2.78711607798977 -1.14737482705699 3.05579305070458e-07 867.259413182612 161.13925366222 5.38204933603924 2.71497668454576e-07 113.012010639182 261.208597617156 0.432650424488782 0.665877979584039 CCDC85C other 0.00291217077732146 1 0.00307443959757962 5.38204933603924 0.432650424488782 0.792810636389168 9.40679021765194 42.3733541967385 0.221997771853898 0.824639126704227 44.0260565726904 64.9974267710939 0.677350762326947 0.49930121482474 C2CD4B other 1 1 1 0.221997771853898 0.677350762326947 0.0210668726827112 222.802830392544 132.09032116875 1.68674607209037 0.0937170674138817 -595.667822752566 475.780298565914 -1.25198085029585 0.212512659555351 RGL3 other 1 1 1 1.68674607209037 -1.25198085029585 4.38466675198948e-12 422.429012500628 85.3094257340257 4.95172730171295 1.95817494537264e-06 -178.664917917565 136.541770103864 -1.30850008595655 0.192705116299477 NAP1L4 other 5.45671777285091e-08 1 0.0210170916886845 4.95172730171295 -1.30850008595655 0.0262309857674915 142.678760980966 56.8664694439388 2.50901387717809 0.0131991655058211 -129.468948267446 302.358522151394 -0.428196788852605 0.669138861254339 TMEM256 other 1 1 1 2.50901387717809 -0.428196788852605 0.00385949269150691 3.08076028444202 4.52404446040273 0.680974802835553 0.497028492497872 -15.6785671562439 7.22220916522008 -2.17088245404841 0.0316503929949697 CHKB-AS1 other 1 1 1 0.680974802835553 -2.17088245404841 0.190636185494238 113.636140094371 68.3582080731784 1.66236276955537 0.0987098433797576 48.275802485546 109.127414901705 0.442380152861035 0.658906697344662 CPT1B other 1 1 1 1.66236276955537 0.442380152861035 1.36228757047442e-06 782.401344404904 199.381240340675 3.92414724207777 0.000132185055771332 -642.183076314749 379.778355686499 -1.69094174720389 0.0929247125463354 HMGN1 other 0.0122810224478269 1 1 3.92414724207777 -1.69094174720389 8.5549474602935e-06 174.443488108721 53.2954371964627 3.2731411408761 0.00132974484094303 -85.6263646659118 84.8778626139847 -1.00881857799991 0.314742141221027 DENND6B other 0.071151498027261 1 1 3.2731411408761 -1.00881857799991 6.17802198705728e-05 991.581116213114 339.121847655878 2.92396707280067 0.00398508383845726 -1197.18959754203 709.329269008719 -1.68777696036017 0.0935049059232788 EIF3CL essential 0.464957934745931 1 1 2.92396707280067 -1.68777696036017 4.71731335257162e-13 127.922430049996 29.2101257029277 4.37938649600451 2.18887053624899e-05 -215.215841812121 58.5549626618907 -3.67545007337508 0.000327308452040867 LCMT1 other 6.04806744933208e-09 1 0.214903309248926 4.37938649600451 -3.67545007337508 9.76228000933351e-11 50.8983656148902 7.25213132590104 7.01840098139238 6.82975128949557e-11 -9.17984071630972 24.5953260840895 -0.37323517016707 0.709490030946206 MFSD2B other 1.15653731270574e-06 1 8.93946146282076e-07 7.01840098139238 -0.37323517016707 1.74778480480572e-08 60.4134701159679 13.6063093954572 4.44010703858745 1.71330898779497e-05 -23.869518973444 21.0267702158866 -1.13519664353442 0.258068161480855 CDPF1 other 0.000183814527921418 1 0.170063050128529 4.44010703858745 -1.13519664353442 4.09494000567626e-06 61.6076146613343 17.0380048183403 3.6158937221932 0.000402821804112968 -35.9948678948264 25.6248233792026 -1.40468745334027 0.162089611174853 LIN52 other 0.0351755346487591 1 1 3.6158937221932 -1.40468745334027 3.56019010484132e-05 28.9181221371095 7.86908099991131 3.67490462195464 0.000331307003751498 -15.6095001256289 15.2847749889819 -1.02124500601946 0.308793640156569 SMIM11A other 0.276306354036735 1 1 3.67490462195464 -1.02124500601946 0.272779123511092 -20.9603768418817 18.0314019951129 -1.16243744371972 0.24684448792947 -43.1651253625091 27.3944608916075 -1.5756880755311 0.117136557089428 DPF3 other 1 1 1 -1.16243744371972 -1.5756880755311 0.0741585243781839 14.5616854350063 6.74491758543352 2.15891228477781 0.0323954710985851 6.50027866697159 10.0294779483181 0.64811734972324 0.517867987283672 CYP2D7 other 1 1 1 2.15891228477781 0.64811734972324 8.86861627098548e-27 104.909484372356 7.89929538827144 13.2808661046049 9.96400286933657e-27 -299.720179252528 143.83685249235 -2.08375095852761 0.0389623040781738 ETFRF1 other 1.2815150511574e-22 1 1.44238905536516e-22 13.2808661046049 -2.08375095852761 1.93394982859593e-08 37.4041851304776 5.9250029772489 6.31293946587098 2.93414775971753e-09 22.2883965205976 29.5658401106641 0.753856357105795 0.452117210447988 C17orf107 other 0.000202697281535139 1 3.6439181027932e-05 6.31293946587098 0.753856357105795 6.84581778215589e-06 225.749333980805 54.9383397498819 4.10914008338395 6.57318332763241e-05 -102.61800511233 107.214637395997 -0.95712682153007 0.340074709324862 ITSN1 other 0.057395336285595 1 0.613278004468103 4.10914008338395 -0.95712682153007 0.002255077922249 139.319373515228 64.7111031587759 2.15294388002307 0.0328501346686939 -168.046953165379 132.78948192002 -1.26551403571703 0.207561986104837 ITPRIPL2 other 1 1 1 2.15294388002307 -1.26551403571703 4.4448515218118e-11 124.452294777458 23.5508522434298 5.2844072686235 4.21273116757783e-07 -31.0407136650269 43.6701235880205 -0.710799766858043 0.478276519815179 DENND1C other 5.33471079647852e-07 1 0.00471615254210338 5.2844072686235 -0.710799766858043 4.49939696647068e-05 64.1597009685323 22.3773414282647 2.86717263416702 0.00477745758225438 -91.5214847774818 43.1595881739255 -2.12053656324677 0.0357113758919401 CRYZL1 other 0.344383843813666 1 1 2.86717263416702 -2.12053656324677 5.13556361364951e-08 50.2890598179408 9.94857371217895 5.05490146355124 1.2148553558346e-06 -12.7827014740371 25.1137414791664 -0.508992317398874 0.611490853207755 RP9P other 0.000521927330055199 1 0.0132066925732779 5.05490146355124 -0.508992317398874 6.34522372121488e-15 288.287959810907 31.8902658809662 9.03999862801309 8.40779700755349e-16 68.7549995176205 139.001661264529 0.49463437265527 0.62159667131576 C5orf51 other 8.49625456270673e-11 1 1.17986615406998e-11 9.03999862801309 0.49463437265527 4.71995267952459e-06 123.343022891943 42.77541391241 2.88350273230574 0.00458837686935192 -187.969159665889 82.1330455110104 -2.28859356786777 0.0236796471039114 CATSPER2P1 other 0.0402045569241904 1 1 2.88350273230574 -2.28859356786777 1.45725546949283e-09 18.3336975541779 2.9964180873053 6.11853787422086 7.57404878384216e-09 -6.83235152062206 11.8788529827106 -0.575169297117019 0.566021680325486 LOH12CR2 other 1.63052314481553e-05 1 9.26533387727411e-05 6.11853787422086 -0.575169297117019 0.301633621424805 22.5767296160386 18.2911618042922 1.23429718995437 0.218997064404747 -27.2679316208718 57.4457209701244 -0.47467298103984 0.635701345987731 CYS1 other 1 1 1 1.23429718995437 -0.47467298103984 2.7327953648648e-16 116.753009328532 16.2458954231157 7.18661583666285 3.09632539418488e-11 -47.8095184042433 39.055528641358 -1.2241421398561 0.222856926068314 PLPP6 other 3.73873733867154e-12 1 4.08776878540288e-07 7.18661583666285 -1.2241421398561 0.847488905816775 -0.967997235182323 62.1791708587446 -0.0155678697836188 0.987599689266544 -129.235882149646 229.892898669713 -0.562156912620947 0.574842653665686 GMNC other 1 1 1 -0.0155678697836188 -0.562156912620947 0.210230157669659 2.10103030508496 2.01339605627871 1.04352558878466 0.298340255955326 -10.469375930372 8.36546518149835 -1.25149955241303 0.212649971857979 TTC23L other 1 1 1 1.04352558878466 -1.25149955241303 0.00491301671133768 13.7446104473011 5.4918108150557 2.50274652754252 0.0133602102558272 -3.71964353706963 9.19588328200039 -0.404490077027217 0.686409986970578 C1QTNF9B other 1 1 1 2.50274652754252 -0.404490077027217 3.7018723816574e-07 44.373033298742 8.72248657829004 5.08719995158088 1.08506775709786e-06 -37.6306297449341 35.800113389929 -1.05113157981003 0.294911422074273 C1RL-AS1 other 0.00350419239647689 1 0.0118359190944234 5.08719995158088 -1.05113157981003 1.94284665219346e-05 666.74487303184 180.73592056035 3.68905567285507 0.000315554319215655 76.1395572023891 348.399485578996 0.218540957590264 0.82730871412585 ZNF316 other 0.155622016840696 1 1 3.68905567285507 0.218540957590264 0.000387722693347879 12.3660485156271 5.17174867446422 2.39107684731184 0.0180558282607061 -17.5751100786083 11.1013420724296 -1.58315183551153 0.115521446352923 SRRM2-AS1 other 1 1 1 2.39107684731184 -1.58315183551153 0.516335481785999 1.20787622553486 7.26488268980221 0.166262316558857 0.86818869649187 -10.2098079236068 10.8566775099644 -0.940417352752356 0.348611838038386 ONECUT3 other 1 1 1 0.166262316558857 -0.940417352752356 0.00267647408752704 15.5564956230052 6.36843611610219 2.44274973312076 0.015761347873267 -12.0196328818975 13.6519567351689 -0.880432974925389 0.380061940551365 CEMP1 other 1 1 1 2.44274973312076 -0.880432974925389 8.31494130116139e-16 1948.38895218613 225.631924985451 8.63525386450418 1.13193262824164e-14 762.515113654509 469.576029535118 1.6238373888237 0.106644031559993 RNPS1 other 1.13008367224084e-11 1 1.57304677346741e-10 8.63525386450418 1.6238373888237 0.0471361684326332 567.321513002366 259.20355071466 2.18871042251614 0.0301854431983753 -37.085517524924 511.600586012709 -0.0724892006359092 0.942310470810992 NYNRIN other 1 1 1 2.18871042251614 -0.0724892006359092 6.11889343136241e-05 129.723810996469 28.6191970989002 4.53275507863405 1.19254340084799e-05 86.8842547188398 134.839975798419 0.644350862601227 0.520345344786161 DNAJC19 other 0.460691486447276 1 0.120244151107503 4.53275507863405 0.644350862601227 0.807616469965178 -1.8436341578486 3.19654214061327 -0.576758909080075 0.564961143183242 -3.46020391282232 5.52464471113693 -0.62632152721912 0.532049735295513 DOK6 other 1 1 1 -0.576758909080075 -0.62632152721912 2.86450802990581e-06 716.485049894952 181.759461967702 3.94194086040082 0.000127942433100579 -403.862347277697 400.980370378565 -1.00718732664248 0.315607511665137 JPT2 other 0.0249756455127488 1 1 3.94194086040082 -1.00718732664248 0.0204796983642679 8.5593708852303 7.41283920485348 1.15466835967872 0.250026515586493 -34.1843169379382 21.7496811639607 -1.57171577276184 0.118082189258338 SERPINB5 other 1 1 1 1.15466835967872 -1.57171577276184 0.244044441126623 8.87308124867017 6.91794387140106 1.28261827699292 0.202118568596648 -15.0597282592176 24.4839935527352 -0.61508463587776 0.539673270199682 ZDHHC11B other 1 1 1 1.28261827699292 -0.61508463587776 0.578348003657678 5.60384381162595 6.30414466596593 0.88891421573482 0.375453780095948 0.633024154631847 11.9410973161654 0.0530122264203376 0.957791774299429 CFAP99 other 1 1 1 0.88891421573482 0.0530122264203376 3.87505037605093e-05 156.157584068687 43.5104467466785 3.58896760995927 0.000447268729381565 -33.6087526830427 64.0986770807776 -0.524328335835834 0.600813974730548 HERC2P9 other 0.298805134497287 1 1 3.58896760995927 -0.524328335835834 0.146896718415234 -135.096511009198 141.207460848452 -0.956723605094685 0.340496318754616 278.996946816328 310.396384146059 0.898840840507484 0.370412132875804 HBA1 other 1 1 1 -0.956723605094685 0.898840840507484 0.426171716052135 -26.3656793874756 48.3621603142777 -0.545171663468719 0.586473048148401 -87.6375697588712 67.4797317186858 -1.29872433583792 0.196100117775033 ATP10A other 1 1 1 -0.545171663468719 -1.29872433583792 0.629317232592761 4.73395653498207 4.91633492080881 0.962903587984862 0.337135380998819 2.26385482771937 19.9427881683875 0.113517468500616 0.909771101242454 ANKUB1 other 1 1 1 0.962903587984862 0.113517468500616 6.4051771188287e-06 13.0151490890357 2.81702709263454 4.62017178431312 8.47834509778645e-06 3.23575769811819 4.46430507465641 0.724806581093077 0.469755003012389 TSSK2 other 0.0538547292151117 1 0.0866571652444753 4.62017178431312 0.724806581093077 0.787554134324157 -0.701699463327352 6.90921280262244 -0.101559972658682 0.91923892659141 -19.2500159723997 27.890159127923 -0.690208180028881 0.491108934601292 FOXL2NB other 1 1 1 -0.101559972658682 -0.690208180028881 0.420529056626239 -55.7951926737587 57.2126393588973 -0.975224938037783 0.330939433539084 -217.614300114024 179.107077793661 -1.21499553671868 0.226180342092192 HCP5 other 1 1 1 -0.975224938037783 -1.21499553671868 0.113844098617144 -4.18909632619717 2.59067240016215 -1.61699191527843 0.107874824833956 -15.2902140048215 8.05898552253806 -1.89728768739692 0.0596143037511234 HCG27 other 1 1 1 -1.61699191527843 -1.89728768739692 0.085750906654948 -31.0598227474151 14.1039206890559 -2.20221195454653 0.0291467496854907 -40.8936484490399 56.0741114060258 -0.729278581927655 0.466946210601754 COL6A6 other 1 1 1 -2.20221195454653 -0.729278581927655 6.74110215528618e-06 41.5289713316459 48.7709231383562 0.851510872858282 0.395834014032904 -509.582270327526 130.784571277009 -3.89634851689196 0.000146357406028298 RAB12 other 0.0565848114914722 1 1 0.851510872858282 -3.89634851689196 0.236879171669475 11.0691507445434 6.49136322713147 1.70521204209903 0.0901977102499379 15.047514788876 17.0815933448236 0.880919858300927 0.379751979034393 TMEM200C other 1 1 1 1.70521204209903 0.880919858300927 0.457936821080122 -1109.7090308498 1224.46124944975 -0.906283503335429 0.366183502167555 -4254.54201497928 3657.19234836842 -1.16333558908307 0.246469698455678 HLA-A other 1 1 1 -0.906283503335429 -1.16333558908307 0.124543511040387 150.137008733624 74.9416583315071 2.00338519424653 0.0469016076938713 -45.0039801673951 325.282185948777 -0.138353657566978 0.89014284659506 HACD2 other 1 1 1 2.00338519424653 -0.138353657566978 1.25499603970339e-05 31.520532220505 7.17250740683792 4.39463223006991 2.05676203092399e-05 -38.2823004696239 30.5689941725119 -1.25232450415552 0.212350156671871 LNP1 other 0.10264617652813 1 0.20267333052725 4.39463223006991 -1.25232450415552 0.0197739273819313 -29.1227108881997 15.8118934262019 -1.84182312030641 0.0676793919937531 43.3462280591553 38.2499207687426 1.1332370678942 0.259108514792515 VGLL3 other 1 1 1 -1.84182312030641 1.1332370678942 0.49329396771485 50.7833010259563 43.6291788360554 1.16397563238089 0.246385867260854 67.1967519266229 95.2430606183211 0.705529111416405 0.48163680664833 PRSS50 other 1 1 1 1.16397563238089 0.705529111416405 9.16992033132772e-06 105.200320866339 23.2860475077035 4.51774054104874 1.23735732158731e-05 3.44833383468689 51.3288780074279 0.067181165233884 0.946524620894985 TRIM71 other 0.0760369793873695 1 0.124564761564194 4.51774054104874 0.067181165233884 8.4938103080247e-08 352.498834987782 73.6367842862785 4.78699387003877 3.86285585631863e-06 -121.222423792327 139.974468910416 -0.866032389591773 0.38778555764713 ANKRD28 other 0.000850485226142513 1 0.0406102036174777 4.78699387003877 -0.866032389591773 1.19147591096569e-05 21.4705617977528 8.33345059777421 2.5764311608792 0.0109160615729235 -38.1958202247191 15.960969263752 -2.39307648511444 0.0179041888250529 COLQ other 0.0976533656627481 1 1 2.5764311608792 -2.39307648511444 6.22910589137158e-09 43.7715876893014 11.8873015895833 3.6822139456492 0.000318801294225329 -65.6054049829018 22.7676222561353 -2.88152202477897 0.0045191434838111 METTL6 other 6.72307398855735e-05 1 1 3.6822139456492 -2.88152202477897 3.17641691141056e-07 109.017393083269 25.7318772187154 4.236666923157 3.95754906114079e-05 -78.252558231803 50.1379220535098 -1.56074593893795 0.120705181629937 THUMPD3-AS1 other 0.003024266541354 1 0.377945935338945 4.236666923157 -1.56074593893795 0.363239741241253 -130.42727459787 117.390104993919 -1.11105850535381 0.268297569101348 25.9176639207585 266.226250110937 0.0973520226121901 0.922575094140453 RNU1-1 other 1 1 1 -1.11105850535381 0.0973520226121901 0.0002346543239852 2.78100885156605 1.18792881779115 2.34105681242509 0.0204943583649092 -7.15920052201542 3.32570306335931 -2.15268783340623 0.0328804643846781 SNORA32 other 1 1 1 2.34105681242509 -2.15268783340623 0.382952067816408 -130.049752024335 128.47598854357 -1.01224947555263 0.313038038109201 58.8253013623408 289.501368339835 0.203195244636246 0.839255987027787 RNU1-2 other 1 1 1 -1.01224947555263 0.203195244636246 0.0048221065839102 3.95826713572401 2.16746785770225 1.8262172247021 0.0697293996462296 -10.4952952413376 6.06800204367171 -1.72961300372057 0.085677406823471 SNORA25 other 1 1 1 1.8262172247021 -1.72961300372057 1.5250392291651e-05 5.85026100771675 1.75811924549885 3.32756781014407 0.001092783619988 -8.89950257224996 4.92199740669516 -1.80810793604734 0.0725158824139343 SNORA18 other 0.123531369774814 1 1 3.32756781014407 -1.80810793604734 0.615921239185961 5.27820018157058 6.32977962714928 0.833867921551591 0.405630417305536 14.7457728098048 17.7207313949519 0.83211987593274 0.40661328110635 SNORA8 other 1 1 1 0.833867921551591 0.83211987593274 0.385425278174441 -142.190265756696 138.074697227767 -1.02980682638862 0.304747389528119 53.4550636717831 311.130618520136 0.171809074677501 0.863817671043254 RNU1-4 other 1 1 1 -1.02980682638862 0.171809074677501 0.905565790189793 4.79668822261416 10.8187105131591 0.443369680405055 0.658124671092048 3.0792520236965 38.9330971188871 0.0790908571772139 0.937063704451288 SNORD15B other 1 1 1 0.443369680405055 0.0790908571772139 0.360766608202044 0.649125568478863 2.67992090865129 0.242218181284143 0.80892924650806 -5.84205703620838 5.2566738193693 -1.11136000386444 0.268123318147987 SNORA7A other 1 1 1 0.242218181284143 -1.11136000386444 0.368750237228146 -120.166697173339 114.374684837051 -1.05064068455829 0.295102187661463 46.422194911487 257.726195681573 0.18012214392379 0.857298180543751 RNU1-3 other 1 1 1 -1.05064068455829 0.18012214392379 0.257792108097818 1.3059069608415 0.827284885052047 1.57854565511533 0.116505583428692 -0.379341340062165 3.57738421189206 -0.106038747194429 0.915690511200183 MIR570 other 1 1 1 1.57854565511533 -0.106038747194429 0.00017073871932799 16.8504990676758 4.31651508288484 3.90372760064912 0.000142726369351336 2.60191583488722 7.98827837736512 0.325716720421233 0.745092619683403 MIR130B other 1 1 1 3.90372760064912 0.325716720421233 9.62044971775196e-05 3.25910472670918 1.51656844391275 2.1489994334187 0.0331868116251883 -10.7386426854225 4.1647288223511 -2.57847344772865 0.010854439506338 SNORA40 other 0.707103054254769 1 1 2.1489994334187 -2.57847344772865 0.204305424662634 1661.95669745958 4628.64405276952 0.359059084801554 0.720039532823506 -10443.5825635104 7347.02402824655 -1.42147113216981 0.157188731645079 GPX3 other 1 1 1 0.359059084801554 -1.42147113216981 0.256649676756104 -29.8486593381028 20.7492447132311 -1.43854196866594 0.152283572214063 -42.9254580352469 31.9464826588004 -1.34366773624833 0.181006999520525 DIO2 other 1 1 1 -1.43854196866594 -1.34366773624833 0.00987874447140173 189.518391712755 121.807235354468 1.55588780224132 0.121814454235045 -947.402563427266 451.860177927428 -2.09667195673841 0.0376787564627147 SELENOH other 1 1 1 1.55588780224132 -2.09667195673841 0.624719898328218 -5.30340428930567 17.2416691236616 -0.307592278408101 0.758813652999222 -51.2857039626064 52.8219895081861 -0.970915795488135 0.333132684929587 DIO1 other 1 1 1 -0.307592278408101 -0.970915795488135 0.000576266968756581 4.41205142012897 1.94792800973031 2.26499716523909 0.024907604980376 -5.26706985349959 4.30073573601036 -1.22469041968751 0.222561927813038 AKR7L other 1 1 1 2.26499716523909 -1.22469041968751 9.8000440612023e-16 239.328785505685 26.3533624867839 9.081527475885 6.30232424047227e-16 -382.084826233037 326.352768968705 -1.17077243573097 0.243571890120015 STK38L other 1.32996397954576e-11 1 8.85287486059139e-12 9.081527475885 -1.17077243573097 1.10485106605494e-12 182.206549873794 30.452074326557 5.98338713875044 1.45842148954628e-08 -181.053545735942 67.1949275061809 -2.69445257931542 0.00782797663836666 SACM1L essential 1.40084066665106e-08 1 0.000176229477071885 5.98338713875044 -2.69445257931542 4.63471935348927e-10 363.269329196033 74.2727049312858 4.89102059137492 2.48811646275009e-06 -497.305093575921 195.809708484267 -2.53973665261791 0.0120780414346645 TSN other 5.32112128974103e-06 1 0.0265059046776767 4.89102059137492 -2.53973665261791 0.0182284340137192 217.417119333821 125.095925606569 1.73800320257916 0.0843186672767453 -634.696767883529 412.321009275969 -1.5393267711438 0.125889063771193 SLC48A1 other 1 1 1 1.73800320257916 -1.5393267711438 0.00378481069547959 7.49259940229493 5.70383371448389 1.31360761504473 0.190944664926701 -25.9731616878405 11.7352580790385 -2.21325866997623 0.0283601121758462 MIR762 other 1 1 1 1.31360761504473 -2.21325866997623 0.00082302462145 13.8741611853033 8.7177068654678 1.59149205168403 0.113523253977263 -27.7594483517944 16.7677527332879 -1.65552586523329 0.0998281758583506 PRR22 other 1 1 1 1.59149205168403 -1.65552586523329 1.89452773136226e-22 41.3156307589211 3.90626403104122 10.5767634831147 4.74721804605832e-20 -25.2985424694253 18.0690849267035 -1.40010092221315 0.16346876295736 TAS2R14 other 2.7069012225704e-18 1 6.79849096376012e-16 10.5767634831147 -1.40010092221315 0.841586343355013 2.85772815454953 9.6832589784189 0.295120492069721 0.768301929222145 17.7161708112313 30.4939763758252 0.580972799115702 0.562113610726079 SNORD17 other 1 1 1 0.295120492069721 0.580972799115702 0.513511333399964 -5.46742602378364 5.33882373857258 -1.02408813092703 0.30737905628937 -9.90391309111445 9.64477560486703 -1.02686817162617 0.306072135206843 SNORA12 other 1 1 1 -1.02408813092703 -1.02686817162617 3.53297477813087e-06 11.3093084036992 2.37265999460244 4.76651034258038 4.3922234865928e-06 -2.44452581997818 8.8337079483794 -0.2767270362868 0.782370662649813 SNORD86 other 0.0305213691082726 1 0.0459997565750864 4.76651034258038 -0.2767270362868 0.0151887926377916 90.0204218855062 41.9214531178227 2.14735929197155 0.0333294921950703 -58.2111069412518 93.1496582027282 -0.624920241946168 0.532948243855368 LINC01089 other 1 1 1 2.14735929197155 -0.624920241946168 1.14522927877096e-05 64.8453773483133 15.033735782186 4.31332426535995 2.83249081351549e-05 -17.5131074020989 36.6307961449874 -0.478097918832577 0.633245545639713 C17orf51 other 0.0940920375438219 1 0.275034857992354 4.31332426535995 -0.478097918832577 0.431849916367224 5.2246742615458 4.46382518672529 1.17044777584103 0.243594383239482 12.7439115901495 18.1856766020468 0.700766425633848 0.484486061479806 KRTAP2-3 other 1 1 1 1.17044777584103 0.700766425633848 0.45905906073336 13.340255906231 17.1047943446503 0.779913259255486 0.43663894115761 35.1265062441998 29.3330689778224 1.19750532311357 0.232949610474629 EWSAT1 other 1 1 1 0.779913259255486 1.19750532311357 0.00850093633914771 83.210783114518 48.1440104505922 1.72837248778668 0.0864723798636675 -110.785723993585 75.3228574980253 -1.47081148636043 0.14393788257315 RNF208 other 1 1 1 1.72837248778668 -1.47081148636043 0.00214638829752098 17.7074755659621 7.41144607691467 2.3892065572895 0.0180714598399273 -39.0425589639704 23.99023939461 -1.62743515484644 0.105649963994793 MAP10 other 1 1 1 2.3892065572895 -1.62743515484644 0.0101710796528141 4.3037962445375 1.41766750965101 3.03582907503959 0.00284132174113549 -8.94312840362959 13.2998785227591 -0.672421811095933 0.502377991457341 POU5F1B other 1 1 1 3.03582907503959 -0.672421811095933 1.62353515202741e-09 290.350814204435 71.5906416685542 4.05570906248728 7.98484055501094e-05 -307.686560721993 146.423809674375 -2.10134240740111 0.037271642767285 ZNF580 other 1.81251464372341e-05 1 0.738438054527411 4.05570906248728 -2.10134240740111 4.74610091556107e-08 39.2680137358941 11.1918214931809 3.50863474366705 0.000590694107082664 -84.7142635677055 31.3741081247955 -2.70013296412255 0.0077066850975031 ZNF611 other 0.000483342917240739 1 1 3.50863474366705 -2.70013296412255 0.184370752841503 2.25189618971661 7.29462020903043 0.308706433671332 0.757959376641792 -17.0011759631505 13.1447890357886 -1.293377620353 0.197804707361835 SYT3 other 1 1 1 0.308706433671332 -1.293377620353 1.1764918484498e-12 630.661060469892 127.112635826959 4.96143484372729 1.80244340407965e-06 -500.604621902685 219.993146734802 -2.27554644011777 0.0242257466400059 NUP62 other 1.49073282117074e-08 1 0.0193850097988749 4.96143484372729 -2.27554644011777 0.00382157727580442 10.9410852044994 4.69195450659089 2.33188220157085 0.0209772840276 -20.7232900917985 14.6356537741826 -1.41594563601624 0.158772240128149 SPHAR other 1 1 1 2.33188220157085 -1.41594563601624 0.173370518987903 17.719855628865 11.4835502990769 1.5430642238132 0.124854369764038 -35.1461566166272 42.6121832477755 -0.824791267142171 0.410757603172982 DENND1B other 1 1 1 1.5430642238132 -0.824791267142171 3.3129734350915e-16 174.479293976324 25.9638692255313 6.72008060357784 3.26896706047376e-10 -98.8071997365005 52.772794227622 -1.87231320953598 0.0630470246616949 FGFR1OP other 4.52750949639604e-12 1 4.18721990776084e-06 6.72008060357784 -1.87231320953598 1.03300937636595e-17 406.979443457887 45.7159458571605 8.90235203115985 1.73611295142073e-15 99.0870073542401 94.476549079988 1.04880002835782 0.295968377632979 SCAF8 other 1.43608963502394e-13 1 2.4300372981036e-11 8.90235203115985 1.04880002835782 0.000104340021498209 87.6760898829864 25.3735176467363 3.45541722293534 0.000719653120054535 -36.8630699665184 64.8032322190192 -0.568846162517483 0.570334549531762 ZNF254 other 0.763247257259401 1 1 3.45541722293534 -0.568846162517483 0.109935768213643 13.8254566390369 14.0455034446207 0.984333291686454 0.326580068615225 -84.8163675060898 52.2425729146728 -1.62351053506916 0.106637475024708 TCTEX1D2 other 1 1 1 0.984333291686454 -1.62351053506916 0.309172949316073 7.45221322679003 5.30860577103212 1.40379857691733 0.162432111762439 -9.94838724751459 22.4559614080207 -0.443017649823768 0.658386994020243 CRYGS other 1 1 1 1.40379857691733 -0.443017649823768 0.0682597793394179 372.42001535945 729.9865443505 0.510173808327943 0.610694881385387 -2792.41704649043 1488.94608472047 -1.87543194152304 0.0627166374205917 CRIP1 other 1 1 1 0.510173808327943 -1.87543194152304 0.0028552189250185 11.2743863594629 4.04558103265066 2.78683983053874 0.00598378337044044 -4.2206521468067 7.34800603482882 -0.574394213450727 0.566528411240329 FAM24B other 1 1 1 2.78683983053874 -0.574394213450727 2.34534928833233e-05 289.361593593413 66.3520118978418 4.36100707901557 2.37630143694716e-05 504.741122921501 270.85659336786 1.86349948747969 0.0643212876828783 TRIM59 other 0.186431814929537 1 0.232426043547802 4.36100707901557 1.86349948747969 0.841078918461996 0.117857241670987 5.9553054213415 0.0197902934161248 0.984237137773074 -10.6333690380671 19.0987722227104 -0.556756681218645 0.578528967925934 ASIC3 other 1 1 1 0.0197902934161248 -0.556756681218645 0.863861419929564 -1.93066022508433 4.50286627429627 -0.428762505363557 0.668699129381375 -6.41213696525778 14.611915511052 -0.438829321207602 0.661404273132606 GIMAP1 other 1 1 1 -0.428762505363557 -0.438829321207602 0.434427788706506 2.0208953239874 21.5708260427905 0.0936865060233905 0.92548238492976 -42.5276005398939 42.6982013624747 -0.996004496275323 0.320841362010645 CFAP206 other 1 1 1 0.0936865060233905 -0.996004496275323 0.000807720770367375 30.3435379061371 10.1394059867898 2.99263467166324 0.00332887866090416 -11.0825373904075 15.7142378751617 -0.705254526401485 0.481953590051763 CCDC183 other 1 1 1 2.99263467166324 -0.705254526401485 0.00276152718542373 49.7759375955755 17.7856030205679 2.79866460181377 0.00580130227680973 -104.948486402793 69.5479352369686 -1.5090093767012 0.133385952082136 ARHGEF35 other 1 1 1 2.79866460181377 -1.5090093767012 0.518905612916029 33.7164794256465 34.7990273935471 0.968891430336315 0.334426570312921 -1.38036739125626 51.8899379125681 -0.0266018316225798 0.978818741553562 DNLZ essential 1 1 1 0.968891430336315 -0.0266018316225798 3.41621935356008e-08 525.978499615655 84.8043428831539 6.20225900860248 4.78189109106426e-09 54.7387760382954 320.983697766812 0.170534442774293 0.864810825284863 SUPT4H1 other 0.000351665620255475 1 5.89463714795491e-05 6.20225900860248 0.170534442774293 1.34591593562099e-08 461.291419141914 92.2967163591263 4.99791799035439 1.57673682637987e-06 -717.090729072907 314.417608474574 -2.28069519564104 0.0239562095911345 NRAS og 0.000142451742626125 1 0.0170208740407707 4.99791799035439 -2.28069519564104 0.579752918656417 2.89062984796776 50.6469146962706 0.0570741547694042 0.954563630102982 -71.9136741947952 80.5242134281985 -0.893068943280257 0.373279949386366 LTC4S other 1 1 1 0.0570741547694042 -0.893068943280257 1.35443608395749e-20 89.657932458631 8.31890064569186 10.777617894146 2.35739881054712e-20 -30.021229562667 41.4556230302979 -0.724177502789574 0.470099961674583 ANKRD39 other 1.91977770540135e-16 1 3.37791675563296e-16 10.777617894146 -0.724177502789574 2.59792461744632e-18 278.389911088127 31.8186120003537 8.74927891527866 3.402071093221e-15 -167.843506764308 129.516370750015 -1.29592503088486 0.196927723491511 QTRT1 other 3.63319757749867e-14 1 4.7520129030111e-11 8.74927891527866 -1.29592503088486 6.27857701913822e-15 97.7427245834491 18.9890031856536 5.14733309736316 7.85142289524972e-07 -107.519455892392 34.3043118959946 -3.13428399958508 0.00205864874934886 CHUK other 8.40827034402990e-11 1 0.00863106918874802 5.14733309736316 -3.13428399958508 0.00437753067029553 760.537276242636 248.791888597463 3.05692151191135 0.0026426011706407 42.6947356048935 409.164510014167 0.104346135991646 0.917032225406496 MXD3 other 1 1 1 3.05692151191135 0.104346135991646 0.0580217902190296 204.759300738227 113.705627471424 1.80078422934421 0.0737194868286976 -380.991742985514 381.806999542254 -0.997864741721035 0.319930849135193 GSTM2 other 1 1 1 1.80078422934421 -0.997864741721035 2.04138614274053e-20 265.903725870147 36.3520650645386 7.31468007107897 1.41220804273537e-11 -55.7975953951941 58.5683188224024 -0.952692454164341 0.342268441770014 COG8 essential 2.88999036227777e-16 1 1.87781303442522e-07 7.31468007107897 -0.952692454164341 0.000152225817597311 41.0752820009808 20.0189070684842 2.05182440082584 0.0418373253335881 -68.8744745323336 35.6162525666263 -1.93379341084501 0.0549258968920395 ARHGAP19 other 1 1 1 2.05182440082584 -1.93379341084501 0.00791200042042995 19.6211683134964 23.4166363808739 0.837915744787434 0.403438348038568 -58.0845123137959 37.1442906825718 -1.56375343953059 0.120025727087366 LCAT other 1 1 1 0.837915744787434 -1.56375343953059 0.448783330884765 28.0319286638862 29.0519204279532 0.964890728425458 0.336152568108052 -61.5933266216024 95.1089173149735 -0.647608324860043 0.518228260411076 PTPRCAP other 1 1 1 0.964890728425458 -0.647608324860043 0.0662277217193005 8.68479861162518 5.64299477138839 1.5390406979747 0.125820274918609 -23.7823673106818 18.5780971369201 -1.28012934453978 0.202399936654374 PVRIG other 1 1 1 1.5390406979747 -1.28012934453978 0.202947566904701 20.7014550637212 11.5930594688786 1.78567660411766 0.0761068967263425 12.1053843986676 38.1752922289032 0.31709997990539 0.751594456312645 GPC2 other 1 1 1 1.78567660411766 0.31709997990539 0.00443395116393853 243.410123089261 80.5077447719674 3.02343735722201 0.00294663968258624 -145.324042167078 256.186396887333 -0.56725901114488 0.571397627668362 SIPA1 other 1 1 1 3.02343735722201 -0.56725901114488 1.83901226749572e-07 164.582506657983 45.0151798384062 3.65615570678148 0.000350123522854212 -136.298289276286 65.5835646470291 -2.07823850395817 0.0393357912410914 SYNJ2BP other 0.00179083014608733 1 1 3.65615570678148 -2.07823850395817 0.00140433126787774 492.277581665522 137.903691154883 3.56972012527667 0.000486097793592013 17.1253891133237 419.114501807692 0.0408608841723677 0.967463399993827 ARL2 essential 1 1 1 3.56972012527667 0.0408608841723677 0.0179176691978904 6.54599786552829 2.66957412014682 2.452075713548 0.0153134037637051 -7.45784418356457 8.76346643320646 -0.851015319155598 0.396073631857841 GBP7 other 1 1 1 2.452075713548 -0.851015319155598 2.13165410731244e-07 281.038969355085 53.2457028535838 5.2781530582457 4.33636176077715e-07 -193.025715302129 174.79077510843 -1.10432438543961 0.271163831974837 RBMXL1 other 0.00206429383752136 1 0.00485195517413355 5.2781530582457 -1.10432438543961 0.000968850802695192 168.996333787117 65.6068508857771 2.57589461322177 0.0109909854463861 -123.505243223572 96.2094288041343 -1.28371246725731 0.201276200021522 SRA1 other 1 1 1 2.57589461322177 -1.28371246725731 8.77553939621992e-05 56.868113772455 25.3020989495611 2.2475650690411 0.0260432232633038 -127.982844311377 57.7651624383084 -2.21557144322168 0.0282075628112588 TMEM110 other 0.648512361380652 1 1 2.2475650690411 -2.21557144322168 1.02187431316234e-05 184.455529270166 48.2720812788651 3.82116379454568 0.000193614166715566 -131.218085731875 103.842079708979 -1.26363114162985 0.208309849048409 DNAJC9 essential 0.0844170370103408 1 1 3.82116379454568 -1.26363114162985 4.70169189436958e-06 383.242094390593 77.7387708309502 4.92987077482852 3.12541329673545e-06 -71.387851581121 287.775329965009 -0.248068003570011 0.804570936257658 C8orf82 other 0.0400584149400288 1 0.0330668726794611 4.92987077482852 -0.248068003570011 4.87803744287992e-05 505.037972372011 201.905238457799 2.50136141206446 0.0133970668995268 -687.759963048102 335.111651401769 -2.05233079832112 0.0417980315805956 VDAC1 other 0.371852794270736 1 1 2.50136141206446 -2.05233079832112 1.01952028169001e-20 129.385139841474 14.9915732764332 8.63052445902175 6.86979217554198e-15 -122.126536069999 44.949878443413 -2.71694919539646 0.0073380918611994 ZBTB9 other 1.44629147160544e-16 1 9.57442935505286e-11 8.63052445902175 -2.71694919539646 0.0117038907721564 201.557446808511 104.801350857006 1.92323329003194 0.0563326289677294 -650.054432624114 388.466579745189 -1.6733857338526 0.0963217600350145 TMX2 essential 1 1 1 1.92323329003194 -1.6733857338526 6.77381346524439e-09 704.645158097591 111.857047355105 6.2995150932297 3.14219360545938e-09 153.402064496599 195.050382977165 0.786474049192502 0.432830553319268 HEXA other 7.29878400880083e-05 1 3.89789116757236e-05 6.2995150932297 0.786474049192502 0.00226793641586017 336.957258064515 145.302406047061 2.3190067338278 0.0217724638120028 -443.433870967742 292.405633741294 -1.51650248763699 0.131539850310469 NDUFS3 other 1 1 1 2.3190067338278 -1.51650248763699 0.000100743489830306 -84.486412710633 115.379230262238 -0.732249751698027 0.465114843613908 -1564.93877408178 356.239888351764 -4.39293528111738 2.05596793742227e-05 LEPROT other 0.738550523945975 0.297601358941874 1 -0.732249751698027 -4.39293528111738 0.00212339163937189 323.431768953069 92.8918956401305 3.48180825382298 0.000650451634199175 -231.869796268713 604.833284380578 -0.383361501849515 0.701987389029199 LBH other 1 1 1 3.48180825382298 -0.383361501849515 0.000267880083717443 26.9059390603929 17.1115157621501 1.57238782550799 0.118101912453043 -69.8898112038487 25.57153587588 -2.73310963968227 0.00707792478976667 ADAT3 essential 1 1 1 1.57238782550799 -2.73310963968227 0.0121199403821932 822.927075524315 297.83636333561 2.76301747143286 0.00646974672003228 -862.897025926436 1210.62100671342 -0.712772222802426 0.477132173539753 PPP1CB essential 1 1 1 2.76301747143286 -0.712772222802426 0.0348265365142753 -63.3897370235399 36.1065563678012 -1.75562954212019 0.0811270701702002 -274.944041873619 108.899623599258 -2.52474740303412 0.0125837105285214 GPSM3 other 1 1 1 -1.75562954212019 -2.52474740303412 0.00511414840398262 -16.2379593020594 10.9469640304948 -1.48332992205196 0.140043795655773 -78.8879763485837 23.873045175853 -3.3044789957662 0.00118518160389129 LAT other 1 1 1 -1.48332992205196 -3.3044789957662 2.59969363197265e-07 199.691302515105 46.4404277924841 4.29994537103345 3.39099327396828e-05 -194.513080756594 101.170838677922 -1.92262002864113 0.0567846812440823 NCKIPSD other 0.00249596585605694 1 0.326349192686707 4.29994537103345 -1.92262002864113 1.37994717263684e-12 808.141874845289 135.428309852421 5.96730385047214 1.61435029775664e-08 -904.022889855153 408.233757801297 -2.21447362590522 0.0282747329172641 ATF6B other 1.74521918923382e-08 1 0.000194642215400518 5.96730385047214 -2.21447362590522 0.0314383010564272 52.3376399008491 53.1132730463515 0.985396623084675 0.32621851749682 -215.46750222661 118.158598067431 -1.82354484354703 0.0704662140480199 TREX1 other 1 1 1 0.985396623084675 -1.82354484354703 0.0018337645354304 -0.360166475001368 2.35829395463246 -0.152723316910466 0.878820358740193 -13.1891227987827 4.12534576521492 -3.19709511624309 0.00169112353767585 SEC14L1P1 other 1 1 1 -0.152723316910466 -3.19709511624309 0.537672768040974 94.7781567207605 131.213767607742 0.722318689941863 0.471186937567646 -67.2935550957953 195.395547127251 -0.344396564226567 0.731014884771766 S1PR3 other 1 1 1 0.722318689941863 -0.344396564226567 0.00240145210212737 160.398862475938 48.4237697030612 3.31239933321006 0.00115922456024025 -92.2528993630766 177.052381758587 -0.521048621016939 0.603101266346292 SLC35F6 other 1 1 1 3.31239933321006 -0.521048621016939 0.0164751412878066 257.346965246603 204.228422257675 1.26009378323409 0.209541654835101 -1430.21850638909 718.280540044875 -1.99116978207392 0.048231022444592 CLIC1 other 1 1 1 1.26009378323409 -1.99116978207392 5.05740374297873e-14 802.959072792483 102.816010229781 7.80966963217078 8.26088494651569e-13 -259.925558148869 361.608529002536 -0.718803726410576 0.473351093733403 DDAH2 other 6.65453184501141e-10 1 1.12339774387667e-08 7.80966963217078 -0.718803726410576 0.0021799462763284 54.5899661075492 23.1301363650603 2.36012296883866 0.0195735556012107 -158.226533564012 89.214453653564 -1.77355268215209 0.0781937612578351 ZNF337-AS1 other 1 1 1 2.36012296883866 -1.77355268215209 3.14640108197489e-07 105.551289297757 41.3889281129451 2.55023007625906 0.012399535642486 -190.052400257274 71.8278480157971 -2.64594311965849 0.00956564757138525 CENPBD1P1 other 0.00299631775036469 1 1 2.55023007625906 -2.64594311965849 6.47832173556904e-05 20.016974739569 6.55961737453322 3.05154608823406 0.00267128448049069 -39.9822084207062 21.523925779209 -1.85757044652733 0.0650912248113245 ATP6V1G2 other 0.486651528775946 1 1 3.05154608823406 -1.85757044652733 4.94569434059223e-09 137.154371411551 27.0802768247181 5.06473298996562 1.16961915285819e-06 -40.5629443972676 53.9983035724525 -0.751189235840383 0.45370021293659 ZNF134 other 5.37201319275128e-05 1 0.0127324740980143 5.06473298996562 -0.751189235840383 3.90894962602157e-12 83.6422098527804 18.3953723259884 4.54691584223133 1.13987948839382e-05 -238.067648129844 54.5656531530852 -4.36295791167276 2.42230839808906e-05 GTF2H4 essential 4.87172391891069e-08 0.350459579035525 0.115127828327776 4.54691584223133 -4.36295791167276 4.84969592792964e-20 330.010831056801 35.333593126112 9.3398605083534 1.03523027370747e-16 -295.326756308825 141.557262364583 -2.08627061145196 0.038602586703076 DDX47 other 6.85359028535017e-16 1 1.46112400831073e-12 9.3398605083534 -2.08627061145196 3.30083357290577e-08 37.251193887297 8.59562294588522 4.33373987223688 2.64435533265903e-05 -38.5422940001737 20.9562969059411 -1.83917483957993 0.067827867319398 ZNF845 other 0.00034015089968794 1 0.257824644934255 4.33373987223688 -1.83917483957993 0.00343797759030421 6.07415159171603 6.26614656146429 0.96935996184178 0.333885588166229 -41.6671821311016 17.3057136909386 -2.40771243967354 0.0172354101125305 ZNF321P other 1 1 1 0.96935996184178 -2.40771243967354 0.000135647071517152 832.456502430149 258.593227805321 3.21917363998741 0.00156798909777714 -512.141304038883 584.542589890117 -0.876140272576469 0.382318349516713 EMP2 other 0.977065856138046 1 1 3.21917363998741 -0.876140272576469 4.17338381655828e-10 134.164256954613 20.0367048510726 6.69592420269796 4.30634442519709e-10 -64.1150561249302 106.534984970826 -0.601821609516231 0.548226300595381 KCTD11 other 4.80481678800355e-06 1 5.49532612099401e-06 6.69592420269796 -0.601821609516231 9.77958768360945e-08 34.5250154234849 6.79443494195788 5.0813666947168 1.12885754828162e-06 -26.2751157985448 24.6435044039162 -1.06620857845077 0.288089338731197 C8orf44 other 0.000973753545656993 1 0.0122989029885282 5.0813666947168 -1.06620857845077 0.144184484766821 109.970269686289 65.0064094265397 1.69168349177261 0.0927288724053035 -39.2049116125811 184.344709941439 -0.212671747537726 0.831864254579813 UBD other 1 1 1 1.69168349177261 -0.212671747537726 0.0609721260867168 20.8924060434189 10.0232460585256 2.08439520704455 0.0387435218427105 -7.98090380278553 32.1027807803489 -0.248604750391931 0.803991432962223 PPM1N other 1 1 1 2.08439520704455 -0.248604750391931 0.0064538704440188 -5.00042055913683 5.26978419277898 -0.948885262889655 0.344325805237052 -42.1861767037816 13.1658980217388 -3.20420047566266 0.00167989131795414 SLC23A3 other 1 1 1 -0.948885262889655 -3.20420047566266 0.757878000143394 9.75246299066384 21.359687307273 0.456582666701451 0.648649567880269 -13.6901531954403 42.9210236091998 -0.318961479579111 0.750211598091194 LTB4R other 1 1 1 0.456582666701451 -0.318961479579111 0.00892580059462245 24.8093850189449 9.18638598582001 2.70066869139185 0.00774414498899965 -3.89073670855692 19.0402639896615 -0.204342582154822 0.838372333106586 LTB4R2 other 1 1 1 2.70066869139185 -0.204342582154822 1.47788643992122e-11 501.282223943951 82.4448962776892 6.08020928615815 9.0799575791344e-09 -108.522857702461 169.383083018698 -0.640694783495477 0.522673229137706 DNASE1 other 1.80612501822773e-07 1 0.000110730082677544 6.08020928615815 -0.640694783495477 2.65717046853621e-05 42.7778793503623 16.8089100855405 2.54495259553807 0.0119974794081759 -90.6682677260514 35.0403727608345 -2.58753719159614 0.010670458871369 MDP1 other 0.209969610423731 1 1 2.54495259553807 -2.58753719159614 3.91408188259438e-08 858.647572438062 152.411949921877 5.63372867336312 8.79343059310379e-08 -239.922787649012 345.226238681875 -0.694972631759024 0.48817701437801 IRF9 other 0.000401310815422402 1 0.00102443972710867 5.63372867336312 -0.694972631759024 9.53342840293477e-12 129.787891717631 20.7689284894302 6.24913758953349 4.6653358765202e-09 -57.8308443559473 51.5062415223967 -1.12279294016824 0.263447262658055 GALT other 1.17318369926515e-07 1 5.75282566933706e-05 6.24913758953349 -1.12279294016824 0.000580150465507091 257.618632703303 79.1841726680157 3.25341067568369 0.00141084139403335 -43.2200190810422 169.68551834627 -0.254706586055535 0.799300933324712 CLDN9 other 1 1 1 3.25341067568369 -0.254706586055535 0.926310204476295 -2.66417858559677 48.3352713769644 -0.0551187261331165 0.956119231849017 19.9036764976553 73.5840822887467 0.270488886707216 0.787166161964674 ITGA1 other 1 1 1 -0.0551187261331165 0.270488886707216 2.31850067149305e-16 98.3994948396703 12.7577348796312 7.71292833469783 1.58238669968775e-12 -177.554446916348 61.9410393753225 -2.86650738681479 0.004747490786005 NUDT19 other 3.17472296947543e-12 1 2.14239335270725e-08 7.71292833469783 -2.86650738681479 0.00450736294662431 26.2420523972248 10.6762527383605 2.45798343672919 0.0151421718176005 -18.3490041765905 27.2668415576154 -0.672942047131447 0.502047912766075 ZNF726 other 1 1 1 2.45798343672919 -0.672942047131447 4.69854986332219e-08 15.2705041763108 2.81332002829797 5.42792999826232 2.19005471514798e-07 0.377709197574345 8.39893544452474 0.0449710799742571 0.964189001532424 ZNF99 other 0.000478722562015721 1 0.00249447232055355 5.42792999826232 0.0449710799742571 6.1062946218898e-15 1019.93918319029 118.511430426993 8.60625156168886 7.65918748255003e-15 -793.832544145212 665.270251616384 -1.19324822087936 0.23458375296662 TAX1BP3 other 8.17999227548357e-11 1 1.06692481631922e-10 8.60625156168886 -1.19324822087936 0.00106419953197085 255.71672422107 105.692145656191 2.41944869823059 0.0167912821098489 -483.074968483828 238.526839723727 -2.02524365410345 0.0446900296905131 AP1G2 other 1 1 1 2.41944869823059 -2.02524365410345 0.318634871396494 232.782111175266 153.552285834571 1.51597945878873 0.131561283224452 310.206330376357 516.273649898561 0.60085640713468 0.548813255959197 ZNF90 other 1 1 1 1.51597945878873 0.60085640713468 3.99190563933395e-14 201.179703123144 24.7098880856813 8.1416679195614 1.23310219487073e-13 16.659223370146 49.4677465679024 0.336769400790847 0.73674923471322 NAXD other 5.26332758546181e-10 1 1.69391248509392e-09 8.1416679195614 0.336769400790847 1.88271050711153e-06 11.979408529879 2.23151677664727 5.36828073857343 2.96262798456888e-07 16.7549798362458 7.33581528173376 2.28399696458632 0.0237750963399587 TM6SF2 other 0.0167561235132926 1 0.00334628830857055 5.36828073857343 2.28399696458632 2.59371533869412e-05 27.9532477575008 10.0506473355351 2.78123854357811 0.00612008521242211 -77.5298886483141 33.8780563926388 -2.28849871875059 0.023524069520971 MEF2B other 0.205136946137318 1 1 2.78123854357811 -2.28849871875059 6.38112438087907e-12 110.550676549168 19.8266375826436 5.57586610883257 1.23922413940077e-07 -55.8143086337087 30.4752727965508 -1.83146214986551 0.0691726475487482 GANC other 7.89536519646167e-08 1 0.00143303879480305 5.57586610883257 -1.83146214986551 2.11441360262014e-06 264.915599646011 63.170396157283 4.19366690350364 4.60168610959377e-05 -164.054181338846 129.908104654367 -1.26284793220043 0.208540318691774 TTLL3 other 0.0187125603831883 1 0.437160180411409 4.19366690350364 -1.26284793220043 1.14587517570661e-08 1139.20900337881 182.76796748664 6.2330889763934 5.0551866116045e-09 104.879222065947 565.008016955147 0.185624307830437 0.853008058000337 REPIN1 other 0.000121703402411799 1 6.22647334951326e-05 6.2330889763934 0.185624307830437 1.4060988746146e-10 88.6407921019965 17.7437804146925 4.99559789573359 1.65320461879161e-06 -57.1374587960641 33.8968359296804 -1.68562808973076 0.0940035180788379 ZNF891 other 1.65343166665931e-06 1 0.0178165861767172 4.99559789573359 -1.68562808973076 5.82973168815038e-15 213.15457983092 26.429928398101 8.06489433570452 1.97555349349444e-13 -210.38967500823 154.939268289379 -1.35788478499386 0.176499433853523 SMIM7 other 7.81184046212151e-11 1 2.70729850748478e-09 8.06489433570452 -1.35788478499386 0.75570258183816 -85.6058978744474 206.924403130097 -0.413706148620012 0.67966117419882 -915.232935538991 1282.48454997791 -0.713640515634091 0.476522667014574 UCA1 other 1 1 1 -0.413706148620012 -0.713640515634091 1.47826630428223e-23 290.388724584103 48.4876838773989 5.98891721284009 1.44981678331604e-08 -253.083620076781 90.1241924124815 -2.80816519185509 0.00563237316019394 FBXO16 other 2.120277360232e-19 1 0.000175210358263743 5.98891721284009 -2.80816519185509 0.430810924014786 -45.8869776276912 71.2086634616672 -0.644401613469307 0.520286316203179 -161.542616434502 124.219407894126 -1.30046197428495 0.19541096893326 TSPAN4 other 1 1 1 -0.644401613469307 -1.30046197428495 0.000494250748195671 124.150424248799 30.9712041282522 4.00857595767637 9.85750967739074e-05 40.3866449282986 131.087224043967 0.308089863240623 0.758468619073863 ARL16 other 1 1 0.90265216115867 4.00857595767637 0.308089863240623 0.0025421030787408 26.3527487473519 8.15202774732417 3.23266180687399 0.00150032768160782 -4.04814753018068 23.9712918075094 -0.168874817539559 0.866116713146511 PAXIP1-AS2 other 1 1 1 3.23266180687399 -0.168874817539559 4.0428815904559e-14 339.957172444338 42.3236600411831 8.03231979733184 2.52319444676104e-13 75.6088020623994 109.71279832352 0.689152069929388 0.491785168997413 LYRM4 essential 5.32892222437992e-10 1 3.45324391983715e-09 8.03231979733184 0.689152069929388 5.21473129509374e-11 175.695989474639 26.6050634599635 6.60385530517657 6.32571695987697e-10 -205.734232122513 137.029708724442 -1.50138414536246 0.135330730461657 MYCBP other 6.24464072587475e-07 1 8.03492568243573e-06 6.60385530517657 -1.50138414536246 0.0208626925742991 6.2823119181552 2.58827169878247 2.42722273751647 0.0163463490219685 -8.49633211618804 9.30634470303566 -0.912961252490099 0.36266274272931 TMEM213 other 1 1 1 2.42722273751647 -0.912961252490099 0.17960868433664 5.31441985244799 2.86552632506491 1.85460514041085 0.0655283077212713 3.13724010731033 12.6172139029954 0.248647612018809 0.803958334228739 PRCD other 1 1 1 1.85460514041085 0.248647612018809 3.4316290838319e-07 596.074172307835 104.10719522208 5.72558093642131 7.0534487658267e-08 -93.1272277799604 430.958080628294 -0.216093471653183 0.829261587098465 ALG3 other 0.00325798865219001 1 0.000825888315990648 5.72558093642131 -0.216093471653183 7.58071678130582e-05 41.27336402958 9.20958280530559 4.48156717867857 1.43806021737903e-05 16.3065020231614 36.6640805038689 0.444754151721892 0.657121875969119 AMZ2P1 other 0.564990821710723 1 0.143633454511817 4.48156717867857 0.444754151721892 1.05704496491265e-12 6.18232090754922 0.992069534199008 6.23174152055863 4.21589496247096e-09 -7.65562952273612 2.74558882215894 -2.78833795539576 0.00596631303170414 GCC2-AS1 other 1.34128435597766e-08 1 5.20873822613287e-05 6.23174152055863 -2.78833795539576 6.01710187193368e-07 7.6250731224407 1.64623646523498 4.63182129874174 7.80205596880788e-06 -7.13117040903568 5.00584662409491 -1.42456829873909 0.156359212363345 ST7-OT4 other 0.00559650645108552 1 0.0799398654564056 4.63182129874174 -1.42456829873909 0.000159307382531004 14.2633409505404 5.02982393562853 2.83575352399646 0.00520327522772642 -37.8886714692539 21.63734674736 -1.75107751942261 0.0819767164364452 ZNF788 other 1 1 1 2.83575352399646 -1.75107751942261 2.38005627890701e-07 175.47887580568 36.7500284147344 4.77493170414323 4.30365916438326e-06 -176.178183433166 130.391465019295 -1.35114812466518 0.178723861466141 SH3D21 other 0.0022934222303548 1 0.045122799099128 4.77493170414323 -1.35114812466518 2.68498003831784e-09 7.85727182803198 1.9184893282197 4.09555149067381 6.74501209763968e-05 -8.55627402635707 3.93533447399884 -2.17421774003944 0.0311959224294042 TTC41P other 2.96206997827224e-05 1 0.628500227258066 4.09555149067381 -2.17421774003944 0.011898502401189 7.4408506366662 3.34316440668224 2.22569091181804 0.027487400153455 -12.721815764723 13.5293971368924 -0.940309138389667 0.348531593589934 C19orf38 other 1 1 1 2.22569091181804 -0.940309138389667 1.88956077839772e-07 31.9839973217276 5.49851282894837 5.81684508460895 3.2308574485351e-08 16.0840977569468 20.9058362923096 0.769359212999455 0.442828716076321 C17orf67 other 0.00183854263738098 1 0.000384536653524648 5.81684508460895 0.769359212999455 0.000798294236154575 237.296465090071 91.0884460424789 2.60512145502415 0.0100785207118884 -606.847135446877 299.949125222996 -2.02316687870224 0.0447746344891392 FIS1 other 1 1 1 2.60512145502415 -2.02316687870224 0.120514378302758 60.9538795172757 143.691120328283 0.424200739600455 0.672061375103794 -298.238540235402 204.712953630794 -1.45686208393673 0.147362186633408 SNURF other 1 1 1 0.424200739600455 -1.45686208393673 2.59306292555577e-08 41.3580283428558 8.0004751093722 5.16944653629467 7.33590168884238e-07 -43.4968616956229 24.114453275793 -1.8037672759219 0.0732612103263836 ANG other 0.0002692117929312 1 0.00807756134958434 5.16944653629467 -1.8037672759219 0.0117978467654774 24.0373375377596 10.5702993649898 2.27404510579656 0.0244624353761406 -11.8170539715317 20.1285795854732 -0.587078383815027 0.558083332667618 SCART1 other 1 1 1 2.27404510579656 -0.587078383815027 0.0783668555410382 -18.4307401524139 14.5069345174961 -1.27047793110154 0.205842955520724 -85.1833809207837 37.5106791562865 -2.27091012044519 0.0245475629920035 COLCA2 other 1 1 1 -1.27047793110154 -2.27091012044519 1.22656438365703e-05 39.6650010718335 9.60255246311185 4.13067267522946 5.95064140460928e-05 -49.9804977389421 33.0912551882049 -1.51038385986511 0.133021560698713 APTR other 0.100394294802328 1 0.557694112439981 4.13067267522946 -1.51038385986511 1.164646881987e-16 56.7696241902084 6.72747528987984 8.43847383216809 2.12617425545431e-14 -48.9377655991417 22.1298683219112 -2.21138982334962 0.028472614231004 SPDYE3 other 1.60080713929114e-12 1 2.94730275291076e-10 8.43847383216809 -2.21138982334962 0.00657183589756656 7.02092275567193 2.40609167744951 2.91797807268682 0.00404750124202368 -4.00628925606139 7.92312444896411 -0.505645125463754 0.613824111226492 MBLAC1 other 1 1 1 2.91797807268682 -0.505645125463754 2.23508395667025e-22 24.0371361204317 2.58879507952951 9.2850671381839 1.57388539928135e-16 4.28112814001997 4.0977850691369 1.04474199300104 0.297800870407775 VAC14-AS1 other 3.19169989012512e-18 1 2.21854885882699e-12 9.2850671381839 1.04474199300104 0.306741949266539 121.36510569976 140.35024545441 0.864730270380492 0.388549496757456 -200.898410489697 234.545680718501 -0.856542784647624 0.393045960800972 NEURL1B other 1 1 1 0.864730270380492 -0.856542784647624 6.61945216538925e-17 146.74973673276 17.6999995633944 8.29094578263463 5.5309183246828e-14 15.1487619294687 33.5267397056463 0.451841188927699 0.652027485686694 HAUS3 essential 9.12557675520562e-13 1 7.6232647269103e-10 8.29094578263463 0.451841188927699 0.920719165089184 8.09374072975378 22.043825814196 0.367165881184812 0.714126231516584 0.894135969427827 34.3791978844098 0.026008052091096 0.979293064599864 LCNL1 other 1 1 1 0.367165881184812 0.026008052091096 5.34447740723346e-07 88.4510119070262 35.0004599527696 2.52713855836135 0.0125218998400758 -202.560747707992 62.4940451869284 -3.24128078286666 0.00146227132772926 BBIP1 other 0.00498925054061236 1 1 2.52713855836135 -3.24128078286666 0.0612417519321877 -0.137177276936986 20.1806865006529 -0.00679745344305049 0.994585143431099 -67.9629983879884 35.0433632300283 -1.93939713896387 0.0542573290402943 AS3MT other 1 1 1 -0.00679745344305049 -1.93939713896387 0.477091625096751 8.89965415142686 12.8662876716527 0.691703339653656 0.49015844007345 -7.40384663233069 20.0038351730841 -0.3701213576431 0.711797321634122 PLIN5 other 1 1 1 0.691703339653656 -0.3701213576431 0.000878939309354539 3.3454792017931 4.06953601143158 0.822078780577304 0.412311337843028 -24.1354690209934 7.67100743547123 -3.14632324685144 0.00198739407104326 SEC14L6 other 1 1 1 0.822078780577304 -3.14632324685144 7.1769914942678e-13 427.341843297137 58.3731556384977 7.3208624516318 1.2801074727332e-11 -281.330199587884 224.166734033206 -1.25500423067327 0.211378381711689 PPME1 other 9.14851105774317e-09 1 1.70356702471334e-07 7.3208624516318 -1.25500423067327 6.62338933909981e-05 326.928872084643 84.0198430717599 3.89109120098474 0.000150416325340564 -313.31767335471 302.792022183228 -1.0347619831447 0.302467897568575 STARD10 other 0.496952902112659 1 1 3.89109120098474 -1.0347619831447 0.301531384075296 123.238257575758 142.737180608427 0.863392824843858 0.389272957793598 351.984090909091 228.888696938917 1.53779586155372 0.126164051028542 MEG3 other 1 1 1 0.863392824843858 1.53779586155372 6.02501361400463e-09 47.563508324729 8.0471147107446 5.91062884454992 2.13773624272027e-08 14.1692049561178 14.8000913621381 0.957372803276455 0.339889457923298 NUTM2D other 6.5082197058478e-05 1 0.000256528349126432 5.91062884454992 0.957372803276455 0.772729970276251 7.51322275955281 11.4997893779259 0.653335684040839 0.514540098276934 -0.8618543894874 20.0983023410532 -0.0428819496722844 0.965852666671391 CPEB1 other 1 1 1 0.653335684040839 -0.0428819496722844 0.065776490152282 11.8741156947801 5.05747206041802 2.3478361428256 0.0201544368939861 4.88891338071812 21.4408121327305 0.228019039132149 0.819933910477487 EML6 other 1 1 1 2.3478361428256 0.228019039132149 0.92864293402692 9.03364742003366 30.1278724183096 0.299843523452511 0.764728900551844 -5.81960086285618 64.9462882225742 -0.0896063658466842 0.928724535363046 SLC6A10P other 1 1 1 0.299843523452511 -0.0896063658466842 0.00419986010690111 290.831257650753 99.5708684132585 2.9208468529539 0.00407916083527718 -85.3502049071276 225.807815947828 -0.377977195115546 0.706028291668661 ZSWIM8 other 1 1 1 2.9208468529539 -0.377977195115546 0.245170467970902 2.06327115722648 3.80189887771737 0.542694906831728 0.588129539622732 -10.8264245609843 8.9347253779567 -1.21172437909449 0.227485957373242 C10orf105 other 1 1 1 0.542694906831728 -1.21172437909449 0.0554969612071805 16.7999136713232 7.14776754874595 2.35037213462134 0.0200308548132999 -7.04620395300825 27.9509285679777 -0.252091945205743 0.801308318312606 ARHGEF33 other 1 1 1 2.35037213462134 -0.252091945205743 3.24483827799406e-06 53.4354480796594 57.1892478715581 0.934361791217653 0.351810595207851 -522.563849217638 121.163099621151 -4.31289601249533 3.11628744939418e-05 IFRD2 other 0.0281327478702085 0.449773767571063 1 0.934361791217653 -4.31289601249533 1.10099295334938e-05 20.217620280282 4.48090387724079 4.51195134601536 1.27804357167278e-05 1.70884526898037 9.57278373333042 0.178510798591483 0.858559545277978 CDIPT-AS1 other 0.0906007101311206 1 0.128456159388831 4.51195134601536 0.178510798591483 1.55577310893509e-07 237.463636221761 59.0511226853682 4.02132297275696 9.21927192950205e-05 -1337.91094869796 404.350942665532 -3.30878652063546 0.00117839588518707 TOMM6 other 0.00152387976020192 1 0.846974512163354 4.02132297275696 -3.30878652063546 0.000297312508382374 29.7162921348315 10.629392106039 2.7956718350759 0.00584352274766686 -36.7560501296456 25.4733005174374 -1.44292452815389 0.15108591301513 SEPT7P2 other 1 1 1 2.7956718350759 -1.44292452815389 9.40765091390761e-11 143.220535058062 24.2770979528488 5.89940920188348 2.30764981312604e-08 -48.2777039541378 55.8908039306194 -0.863786178743605 0.389075360475312 POLR2J4 other 1.11527701584375e-06 1 0.000276548753605024 5.89940920188348 -0.863786178743605 0.00294646440189001 12.4992637081223 4.17079032041326 2.99685736944068 0.00317755617496367 -2.76593400240103 12.7514279065587 -0.216911707666744 0.82856239764023 LINC01347 other 1 1 1 2.99685736944068 -0.216911707666744 0.0522297238623049 19.6279120758647 8.02008904283952 2.44734341115438 0.0155229778783975 9.09695499643717 23.4693412839503 0.387610154301953 0.69884325038946 EVPLL other 1 1 1 2.44734341115438 0.387610154301953 0.105868458094112 11.8556793157374 6.75137611760809 1.75603893328012 0.0811503213326333 -15.64198768072 24.3782626866935 -0.641636685999693 0.52210159471748 SMTNL1 other 1 1 1 1.75603893328012 -0.641636685999693 0.223656287276677 0.68700239808154 6.07075279526819 0.113165932010445 0.910047354927795 -15.0690700772715 9.92066643247264 -1.51895743898282 0.130836930818567 LINC01588 other 1 1 1 0.113165932010445 -1.51895743898282 0.364014494978035 -3.93594108893273 3.12355187468693 -1.26008507200708 0.209532512297217 -10.3692010934619 9.21866329573299 -1.12480527391226 0.262410367731104 HLA-F-AS1 other 1 1 1 -1.26008507200708 -1.12480527391226 2.93800690364239e-08 73.7004925880533 12.1226493983065 6.07956975134075 9.00650650731565e-09 -19.2963853749915 49.7826823941666 -0.387612407507647 0.698834641619352 ZSWIM7 other 0.000303936814181806 1 0.000109843353363222 6.07956975134075 -0.387612407507647 1.21759538328437e-05 97.2889720898572 66.487297018065 1.46327157898182 0.145444421801615 -219.305362098759 94.7438189710874 -2.31471946645599 0.0219579596699535 ARHGEF28 other 0.0996845340294916 1 1 1.46327157898182 -2.31471946645599 0.138949727582853 6.5732364519871 3.42506103599507 1.91915892385766 0.0568887662360202 1.39834765849782 13.6613398341482 0.102358017257025 0.918611059935445 LRRC69 other 1 1 1 1.91915892385766 0.102358017257025 1.55848077872756e-06 14.4040225575495 5.14936982713657 2.79723986450575 0.00581663178977041 -23.2239833180964 11.4697453971783 -2.02480373485968 0.0446267020064938 ISPD other 0.0139795725851862 1 1 2.79723986450575 -2.02480373485968 0.000522671532797999 78.1974906618139 22.3555343281907 3.49790300307006 0.000615200363881417 39.8222248826741 42.608449582168 0.93460863451225 0.351472408164343 COL28A1 other 1 1 1 3.49790300307006 0.93460863451225 1.59514592460107e-07 1181.84705615257 264.174681350372 4.4737332514659 1.55623416749006e-05 -2667.51560574283 1143.35296596208 -2.33306396638262 0.0210389845316664 PHB2 essential 0.00156148834559199 1 0.15500092308201 4.4737332514659 -2.33306396638262 3.48184673380421e-05 79.1313916158751 21.5471417997016 3.67247741493821 0.000332824623628837 -148.058515175483 96.3971047750808 -1.53592284250592 0.126650019349939 CD27-AS1 other 0.270713583553277 1 1 3.67247741493821 -1.53592284250592 7.00635138623388e-17 198.329635792198 21.0445333860364 9.42428288401944 9.5862480377245e-17 -53.8358291735979 111.720705790007 -0.481878706305248 0.630618640354001 NEURL4 other 9.65755475078478e-13 1 1.3535782229267e-12 9.42428288401944 -0.481878706305248 0.431410303961794 3.82761811137457 34.3862767277831 0.111312374459023 0.911517449390604 -58.59048458914 66.7301987538632 -0.878020531682411 0.38133678266969 GRID2IP other 1 1 1 0.111312374459023 -0.878020531682411 1.29147950807747e-10 36.6360412233488 5.09533913483095 7.19010849992505 2.57793153013154e-11 17.8418867609626 27.4376847268781 0.650269399133543 0.516480882731001 ALOX12-AS1 other 1.52123371256445e-06 1 3.41086120751704e-07 7.19010849992505 0.650269399133543 0.221310061948714 20.2394476115937 24.1462622472628 0.83820209539421 0.403242058145146 73.449334750398 42.1372456301175 1.74309767171635 0.0833521082111874 MUC5AC other 1 1 1 0.83820209539421 1.74309767171635 1.67087116880765e-19 58.3017572316843 6.34288632142881 9.1916761986917 6.17728853701144e-16 -16.8023141389564 16.5558989652947 -1.01488382927308 0.311976653248731 MSMP other 2.35442456396685e-15 1 8.67847266564737e-12 9.1916761986917 -1.01488382927308 0.0713515720408332 32.7863922153534 33.2632003230404 0.985665597325079 0.326022232901831 -116.750800509641 85.8976062831829 -1.35918572776921 0.176304797680701 FAM166B other 1 1 1 0.985665597325079 -1.35918572776921 2.06641609178858e-08 319.949682567273 99.083752557807 3.22908321806452 0.00154508908563597 -415.663090892537 148.681835940483 -2.79565481730348 0.00590209633568572 PEX26 other 0.000216085130718332 1 1 3.22908321806452 -2.79565481730348 0.273410574593771 -39.8202890948062 33.1171086630446 -1.20240838353264 0.231087474469089 -183.900839333942 134.90763764297 -1.36316106743068 0.17486091179975 C5orf49 other 1 1 1 -1.20240838353264 -1.36316106743068 0.727880592556265 -2.70069771129551 4.80337784749895 -0.562249691163007 0.574768722268548 -13.555032859383 19.7234205224363 -0.687255683869006 0.492962050975339 UBE2QL1 other 1 1 1 -0.562249691163007 -0.687255683869006 6.54612478891594e-13 153.565058849014 20.2174051737491 7.5956858721122 3.12578199930229e-12 -14.1411198224461 77.0512151016185 -0.183528836031933 0.854632609160512 FASTKD5 essential 8.35612829305119e-09 1 4.2094906184604e-08 7.5956858721122 -0.183528836031933 8.83057710567672e-14 181.517684682966 32.4469751053849 5.5942868046532 1.07082366779169e-07 -337.592773038241 74.0759189164681 -4.55738893254808 1.09130689200099e-05 DHRS4-AS1 other 1.15397981616983e-09 0.158414108442864 0.00124194128990481 5.5942868046532 -4.55738893254808 1.3666201759887e-15 135.125910241491 20.7200508616954 6.52150475611501 1.04946729197811e-09 -212.537995209361 48.8535633239461 -4.35051162593871 2.52704006018922e-05 HOMEZ other 1.8510870283767e-11 0.365409992703361 1.3234832019136e-05 6.52150475611501 -4.35051162593871 4.61640436240354e-05 3.33937761675684 1.03205092394285 3.23567136009051 0.00149935878625282 -5.22612378084625 2.43336107150144 -2.14769761958163 0.0333770348853475 RNF212B other 0.352831785418502 1 1 3.23567136009051 -2.14769761958163 5.4082844144575e-13 265.225472456775 36.4052122028283 7.28537086884965 1.69497349314039e-11 -140.477784479293 135.541128155806 -1.03642183292006 0.301673308097875 VPS16 other 6.92422653582993e-09 1 2.24973831744524e-07 7.28537086884965 -1.03642183292006 9.3557672376191e-08 14.7363128976915 3.46566298762687 4.25209056688522 3.80454297549703e-05 -0.817425673768107 6.72978731628328 -0.121463819783766 0.90349418444587 FAM66B other 0.000933050666607753 1 0.364056717325311 4.25209056688522 -0.121463819783766 0.0102787484462616 91.5996834329934 123.140093767373 0.743865630036277 0.458300149328195 -449.515511783327 223.327270123273 -2.01281066810695 0.0462001313285499 MYL5 other 1 1 1 0.743865630036277 -2.01281066810695 9.42286308296127e-16 97.5016556333274 13.8805142613833 7.02435470309518 6.7381479946579e-11 10.4798048148701 25.993653707468 0.403167824454751 0.68739130070237 ZNF407 other 1.27915366351199e-11 1 8.82495242860345e-07 7.02435470309518 0.403167824454751 8.90341263031932e-10 149.463879461589 27.9273434356696 5.35188317520704 3.56517486185052e-07 -69.7709489775376 50.3334594191361 -1.38617432186693 0.167945623449035 MCM3AP-AS1 other 1.00742113912063e-05 1 0.0040069000272338 5.35188317520704 -1.38617432186693 0.0128913898176032 144.657224920605 48.5463971054378 2.97977262053915 0.00337626086043382 115.06377265085 196.991464243768 0.584105372750891 0.560044694813988 NPEPL1 other 1 1 1 2.97977262053915 0.584105372750891 0.00820629069539145 7.4498903404215 4.41383709976038 1.68784895591773 0.0934910500270232 -13.447728934236 8.36942046487496 -1.60676942814307 0.110180345138172 AATBC other 1 1 1 1.68784895591773 -1.60676942814307 0.115473463728919 26.1980543135098 26.6653677210157 0.982474893562496 0.327427177042719 -44.0984300224283 45.2586150138055 -0.974365433166187 0.331423217558572 SIAH3 other 1 1 1 0.982474893562496 -0.974365433166187 4.4399387546856e-14 112.174825558433 15.1654583933782 7.39673161527462 8.40805111743406e-12 20.7884484574539 35.2768613483586 0.589294162316999 0.55652745365246 RSC1A1 other 5.8491753154228e-10 1 1.12213850213275e-07 7.39673161527462 0.589294162316999 1.15086260870849e-10 70.9495349361141 16.0739593360747 4.41394266668838 1.91495755977365e-05 -70.6741763487926 34.3261049674986 -2.05890462712591 0.0412101068778115 TMEM242 other 1.3592838271456e-06 1 0.189140358178844 4.41394266668838 -2.05890462712591 1.62604191966377e-10 146.72714225284 28.7937797202657 5.09579303857669 1.03710725124029e-06 -307.363865723954 92.0387552239128 -3.33950480942725 0.00106050018116435 TMEM167B other 1.90734717176561e-06 1 0.0113252111835439 5.09579303857669 -3.33950480942725 0.00348327531897373 71.6823389957203 50.4123749782576 1.42191949946092 0.157227034100261 -199.588524872487 112.623078862933 -1.77218139379224 0.0784939757412271 TNFRSF25 other 1 1 1 1.42191949946092 -1.77218139379224 3.2482693560997e-15 137.703560334528 18.3197101162183 7.51668882645802 6.80063031123408e-12 -20.1102986857825 41.8294914156811 -0.480768424505481 0.631453603933777 SLC35E2 other 4.3692471108897e-11 1 9.10060348249344e-08 7.51668882645802 -0.480768424505481 0.107718170628621 63.1560734270508 45.1299455688089 1.39942720140794 0.163670227337298 -118.142602702334 139.419154684734 -0.847391471921396 0.398075146277971 LINC01139 other 1 1 1 1.39942720140794 -0.847391471921396 0.0777053277296538 15.7810845001996 7.53604766436861 2.094079709025 0.0379125447565103 -4.04119426820528 24.5283199534658 -0.164756260350162 0.869354734060956 LINC01356 other 1 1 1 2.094079709025 -0.164756260350162 8.96264400179251e-09 65.0805926827554 13.686433720272 4.75511692913544 4.5894463910697e-06 -102.001794589702 41.5971202543472 -2.45213596436504 0.0153407432147744 CYB5RL other 9.58375523111673e-05 1 0.048005609250589 4.75511692913544 -2.45213596436504 2.26999911284371e-08 41.6072785186305 11.43445137751 3.63876474217786 0.000372621044649932 -59.2147191363362 26.1955449186315 -2.26048816011534 0.0251832670271197 C1orf167 other 0.00023661724592683 1 1 3.63876474217786 -2.26048816011534 0.0762406558782515 18.4005258545136 10.7980676422234 1.70405728730227 0.0906374339456539 -8.43935144609994 24.3157735938759 -0.347073121631033 0.729068959417516 TTC34 other 1 1 1 1.70405728730227 -0.347073121631033 3.57328216540698e-09 166.08559139785 27.5660125590045 6.02501326741931 1.49478855102182e-08 50.1105376344085 62.9416228961303 0.796143081933297 0.427336378343064 MMP23A other 3.91453061220334e-05 1 0.000180540561192415 6.02501326741931 0.796143081933297 0.0745227846532958 -126.919217411746 56.5334579294925 -2.24502837894751 0.0264690032624625 -208.501740908466 127.283077389077 -1.63809475057804 0.103838855300163 ATAD3C other 1 1 1 -2.24502837894751 -1.63809475057804 0.500272513407994 123.327238221562 243.524882693776 0.506425613914129 0.613286884571183 1002.30902690395 849.743866856866 1.17954252569238 0.240013070725445 IFI30 other 1 1 1 0.506425613914129 1.17954252569238 1.14659301200692e-13 14.7264030226644 1.80549491559715 8.1564356096754 1.06769653306291e-13 2.54649974001309 7.6835221716224 0.331423490833162 0.740769424586534 IGSF23 other 1.49297876093422e-09 1 1.46754888469497e-09 8.1564356096754 0.331423490833162 0.798590843976455 -1.54414916416631 5.01322187196145 -0.308015324995411 0.7584923521744 -15.304677453922 22.9707059753782 -0.666269354991823 0.506248919186432 CCDC7 other 1 1 1 -0.308015324995411 -0.666269354991823 3.65379226827543e-07 109.22791820117 32.5654889390162 3.35410036083646 0.00100387926792905 -106.997510137298 50.9833218295092 -2.09867671029956 0.0374879470274033 FNIP1 other 0.00346014127805683 1 1 3.35410036083646 -2.09867671029956 0.0877716049933088 1.35713431248748 5.05452620515947 0.268498818168589 0.788716345214237 -12.5346314880043 8.06907310577097 -1.55341652302538 0.122614042728755 SYCE3 other 1 1 1 0.268498818168589 -1.55341652302538 0.00062492971416991 -44.7360616061602 67.7289728420787 -0.660515872733959 0.509978078773674 -336.358542965408 104.730089507033 -3.21167053851149 0.00162799915520279 CKLF other 1 1 1 -0.660515872733959 -3.21167053851149 8.85077740613381e-11 171.699974618189 25.0693688395375 6.84899471212045 1.7286940778502e-10 -58.0585680119026 76.018881249763 -0.763738785120356 0.446206785078419 PAM16 essential 1.05058727810808e-06 1 2.23658439792259e-06 6.84899471212045 -0.763738785120356 3.67825972139002e-05 294.616825216663 70.5147183211835 4.17808979785936 4.87911265737003e-05 131.787395515712 111.200362349497 1.18513458707545 0.2377664804448 TENM3 other 0.284770867630015 1 0.462344715412384 4.17808979785936 1.18513458707545 4.52999746915321e-06 64.8887267501722 20.3924217343222 3.18200200032931 0.00178255837300477 -56.7553907008096 43.622339929785 -1.30106250128177 0.195258980601516 LINC00339 other 0.0386907083840375 1 1 3.18200200032931 -1.30106250128177 1.02524954383862e-07 317.558641459905 54.9952359158232 5.7742936487438 4.21482152133341e-08 -154.631250054931 219.137715721152 -0.705635036607282 0.481495161265106 CEBPZOS other 0.00101940562143874 1 0.000499161312771516 5.7742936487438 -0.705635036607282 3.26109447034054e-14 265.424424837986 55.9348040398363 4.74524635232392 4.81277223868565e-06 -379.276818700191 111.388048733806 -3.4050046033806 0.000849024003092302 ZNF579 other 4.30529691974358e-10 1 0.0502453421718782 4.74524635232392 -3.4050046033806 0.000922994615591866 594.419660366337 163.928315970598 3.62609508215135 0.000389862685573936 -270.74118579714 882.730929657451 -0.306708620601074 0.759476803244562 RNASEK other 1 1 1 3.62609508215135 -0.306708620601074 0.151892358896432 -41.5874843777899 36.6871212924859 -1.13357175250236 0.258758968239227 -112.201678271737 57.4370473429549 -1.95347225287861 0.0525998460144752 FAM19A5 other 1 1 1 -1.13357175250236 -1.95347225287861 0.215948503224031 86.6888096393677 62.6836309260095 1.38295769339995 0.168679727741566 -17.9669930433928 148.342028756098 -0.12111869571997 0.903754909719524 RPL23P8 other 1 1 1 1.38295769339995 -0.12111869571997 7.50619699541167e-11 28.1292022902239 13.8629934240309 2.02908574142892 0.0441948020890908 -102.977199311386 26.5059576492751 -3.88505862244151 0.000152298383823411 UMAD1 other 8.93237442453989e-07 1 1 2.02908574142892 -3.88505862244151 0.236718911892908 8.01715853715531 10.5030275661301 0.763318813235227 0.446456396929344 -27.3009815521731 27.2111721892854 -1.00330045917401 0.317310437159293 PPP1R3G other 1 1 1 0.763318813235227 -1.00330045917401 9.32141896753161e-06 37.3159110961725 8.13889093001928 4.58488895072146 9.38083676772432e-06 -22.9562950202839 27.6027373734564 -0.831667334644835 0.406892852878033 FAM228B other 0.0772745632408371 1 0.0954687757851304 4.58488895072146 -0.831667334644835 8.75091305201773e-09 13.1335838658383 2.5888841601832 5.07306741175664 1.10598654602977e-06 -15.1988296411887 10.3603128027971 -1.46702420385274 0.144395531609678 ZGLP1 other 9.36610223957458e-05 1 0.0120585713113626 5.07306741175664 -1.46702420385274 0.000321813961015726 166.080874924227 46.3736506412097 3.58136296426576 0.000459440617238956 -269.037755102038 250.108364717555 -1.0756847553094 0.283772716182075 VAMP2 other 1 1 1 3.58136296426576 -1.0756847553094 0.787280811221708 23.5334522267462 110.785619900561 0.212423347433262 0.832055869703092 -176.472590181458 330.999114376102 -0.533151245779283 0.594692503133954 RPL21P28 other 1 1 1 0.212423347433262 -0.533151245779283 0.000161064649910288 30.4934515257303 100.370146487152 0.303809973313466 0.761726969172875 -619.460753243114 175.306080798149 -3.53359535746152 0.000557038671081706 MIR1282 other 1 1 1 0.303809973313466 -3.53359535746152 1.21981147472911e-09 123.035164714294 22.4127917656319 5.48950643903976 1.7087315669959e-07 -66.7892940292215 47.5005099132016 -1.40607530637601 0.161797801647756 PPP3CB-AS1 other 1.37119007874299e-05 1 0.001960085980501 5.48950643903976 -1.40607530637601 7.57351207507894e-08 33.769502017788 5.71588671903861 5.90800757217734 2.12123587965063e-08 36.4613261987787 10.5362071916981 3.46057414545794 0.000696503338287699 EBF2 other 0.000761440904028437 1 0.000254611942634465 5.90800757217734 3.46057414545794 0.000422124440146545 21.05109267186 8.62387645597839 2.44102437915453 0.0158176613549281 -46.3886427304575 25.150786031587 -1.84442119113883 0.0671075747831985 C6orf226 other 1 1 1 2.44102437915453 -1.84442119113883 2.53482045942889e-14 174.345804848881 26.9603043654744 6.46675951745373 1.55506163376658e-09 -151.625370631785 69.0496233285066 -2.1958899024028 0.0297462264018063 FANCG other 3.35483487805414e-10 1 1.95035830107004e-05 6.46675951745373 -2.1958899024028 1.39412733795902e-19 399.548595806964 40.5566094646447 9.85162717202164 4.40432625364504e-18 -196.498101823746 133.409992361607 -1.47288893691815 0.142808750640237 AP4M1 other 1.96502248285324e-15 1 6.26163063480716e-14 9.85162717202164 -1.47288893691815 4.72935931744517e-08 17.9918372899803 3.04981372419149 5.89932334137879 2.52455948258757e-08 -5.21469164126126 11.6298021490215 -0.448390400321642 0.654550128687579 C2orf16 other 0.000481685246481791 1 0.000302013050901951 5.89932334137879 -0.448390400321642 0.0104040802856663 279.365140760746 95.0660063005328 2.93864391313113 0.00380400779669869 -124.975822437599 378.490041401357 -0.330195801123002 0.741700776774942 PLXNA4 other 1 1 1 2.93864391313113 -0.330195801123002 0.000830921791211221 8.14605533287708 4.26949832974817 1.90796545723384 0.0582446536974644 -23.4141441297322 11.7724644187323 -1.98889062620362 0.0484733178230065 ZNF816-ZNF321P other 1 1 1 1.90796545723384 -1.98889062620362 8.54109565390653e-07 11.9476125511597 4.28531108264511 2.78803856260185 0.00611851931621653 -30.7827000667615 9.24325038207463 -3.33028954040433 0.00113606829737509 ARIH2OS other 0.00783474704332845 1 1 2.78803856260185 -3.33028954040433 0.000337557524651231 52.062269298668 13.0915658844417 3.97677938286512 0.000107171359945214 18.5869309367143 21.390999572608 0.868913622929317 0.38624654752515 ZBED8 other 1 1 0.976624635015544 3.97677938286512 0.868913622929317 0.128909880374005 3.2829965820969 2.64196338737769 1.24263515451495 0.215891087939106 -5.08151784314786 7.47839847124206 -0.679492790159373 0.497845723918635 HMSD other 1 1 1 1.24263515451495 -0.679492790159373 0.000553914380083141 393.271145800201 139.69360956353 2.81524077607393 0.00552911726023489 -334.780205470329 280.099372416235 -1.19521940582158 0.23388756143791 NPTXR other 1 1 1 2.81524077607393 -1.19521940582158 1.52593991314548e-09 47.1292080556863 8.95894675116793 5.26057463725212 4.70307259090725e-07 -80.319382859785 29.5313571780868 -2.71979991896155 0.0072780387123559 FAM200A other 1.70615341688796e-05 1 0.00525003993322976 5.26057463725212 -2.71979991896155 2.3400506811853e-20 202.148123099138 61.8401593193131 3.26888102042786 0.00133011512070672 -662.549323884171 125.527080957661 -5.27813854054043 4.33665281120813e-07 PPP2R2A other 3.31140571894531e-16 0.00633194676964499 1 3.26888102042786 -5.27813854054043 0.018218706342701 3.73820138608478 2.98694664137877 1.25151260966591 0.212609024066197 -6.92049790274332 5.2511108062522 -1.31791123023027 0.189453104852033 C19orf73 other 1 1 1 1.25151260966591 -1.31791123023027 0.000891182372280529 56.9668720264847 17.9682658280999 3.17041569684461 0.001836954559844 0.484813885988884 35.0014199009127 0.0138512633876388 0.988966572300802 ZNF880 other 1 1 1 3.17041569684461 0.0138512633876388 0.15393847278096 35.1499591206397 27.7226749877538 1.26791368928745 0.206705873456284 -143.298078670058 114.070422860854 -1.2562246643449 0.210900593053274 TRIM16 other 1 1 1 1.26791368928745 -1.2562246643449 1.99333334624962e-13 126.593876936964 15.2419116813681 8.30564299173272 4.48032027605858e-14 118.857805526303 68.4611239531412 1.73613576089776 0.0845141605492751 FXYD7 other 2.58096801672401e-09 1 6.18104985285042e-10 8.30564299173272 1.73613576089776 0.0375142023654876 13.3248498557527 6.4942686414496 2.05178605804924 0.0419411909879229 -13.1261574564083 22.017920552692 -0.596157908054738 0.551974330744131 XKR9 other 1 1 1 2.05178605804924 -0.596157908054738 0.000160049647326238 5.36133435100794 2.14581098923103 2.4985119276182 0.0135571338757372 -13.7682956943384 5.34012145034924 -2.57827388802889 0.0108986363996778 LINC01465 other 1 1 1 2.4985119276182 -2.57827388802889 0.311499951244187 33.4118447436267 35.9734970586018 0.928790567377919 0.354460623522751 200.540984509618 147.704069054196 1.35772146152612 0.176551162589279 SLC12A8 other 1 1 1 0.928790567377919 1.35772146152612 0.0256796640636453 210.741655847136 174.423425882375 1.20821876293872 0.228827263724056 -452.269183354974 301.186432073616 -1.50162535623261 0.135254893357102 APOL6 other 1 1 1 1.20821876293872 -1.50162535623261 2.4598565582645e-08 698.286140075834 171.649526198582 4.06809244126888 8.23494325982217e-05 -742.869503791746 383.590680040916 -1.93662031546884 0.0549953985456409 CCNL2 other 0.000255702089231595 1 0.760085262881587 4.06809244126888 -1.93662031546884 7.58624911109512e-07 5000.45459245159 1054.19897364071 4.74336886819608 4.82723789859908e-06 -1659.53784773626 3390.72942076309 -0.489433877434777 0.625244787747612 UBA52 essential 0.00698541818149639 1 0.0503867091855772 4.74336886819608 -0.489433877434777 0.175279235030022 21.1874698305428 11.2993294770545 1.87510859591874 0.0627479977878473 23.7543253474251 36.0627020171206 0.658695106543816 0.511115022164807 MYBPHL other 1 1 1 1.87510859591874 0.658695106543816 2.97685218997153e-07 66.7870764535118 22.6794176612587 2.94483206981096 0.00372942164372691 -212.713976890684 69.4555519574905 -3.06259141127945 0.00258781233130114 PPT2 other 0.00283932161879485 1 1 2.94483206981096 -3.06259141127945 0.000242273149756188 34.5121873088907 8.53437014624195 4.04390560961172 9.32967789554611e-05 5.06866827805128 29.1605900111675 0.173819126297176 0.862300496671348 EXOC3-AS1 other 1 1 0.856464430811133 4.04390560961172 0.173819126297176 0.428583989764701 -12.8677697841722 68.7361895804485 -0.187205166051747 0.851780833513915 -389.281055155869 298.137082045134 -1.30571162931331 0.193871326244345 TIAF1 other 1 1 1 -0.187205166051747 -1.30571162931331 0.328920866311843 22.4054851026114 22.7567600486879 0.984563929780646 0.326423742075433 -62.2120235903729 78.2593484680498 -0.794946863322937 0.427900439659669 BTBD19 other 1 1 1 0.984563929780646 -0.794946863322937 2.12319741628936e-08 19.6215373545989 3.9026375298267 5.02776319979433 1.37191903665397e-06 -24.4552815196777 12.1680585742136 -2.00979321150729 0.0462108901131218 FAM185A other 0.000221852898028075 1 0.0148674866002191 5.02776319979433 -2.00979321150729 0.570085992141695 2.96695767697856 3.45259789619888 0.85934063745014 0.391471197542748 7.77962611501236 8.44556704338908 0.92114905666423 0.358394934821039 RAB6C other 1 1 1 0.85934063745014 0.92114905666423 8.25815510960601e-15 89.1931187258146 14.3189352536648 6.22903289565376 5.56144451988422e-09 -33.9445948869144 25.0798288207672 -1.35346198450951 0.17816993818784 URAHP other 1.10361984884775e-10 1 6.8405767594576e-05 6.22903289565376 -1.35346198450951 0.228124114635689 9.70723678004792 7.46021809844458 1.30120013275106 0.195120836888651 -16.3322863018092 23.0612399835359 -0.708213708953607 0.47987622122169 LINC01124 other 1 1 1 1.30120013275106 -0.708213708953607 0.568543633554173 5.28577277379736 5.09007313861086 1.03844731300657 0.300732898572555 2.58222108495395 12.3199599812034 0.209596548113278 0.834266973302547 POTEJ other 1 1 1 1.03844731300657 0.209596548113278 0.00673921846863531 6.50302243065275 6.3125135289809 1.03017956330663 0.304583955141087 -39.8613393163402 17.8557257215017 -2.23241216504236 0.0270691789593582 DCDC2B other 1 1 1 1.03017956330663 -2.23241216504236 0.795502000153824 0.925397738163968 33.8939170465703 0.0273027675406318 0.978256314805792 -45.9508453133983 75.4073163380488 -0.60936852741718 0.543247150730141 C10orf55 other 1 1 1 0.0273027675406318 -0.60936852741718 1.61895576357499e-06 6.81670822942642 1.26222538162541 5.40054757942543 2.5492782056838e-07 3.70878359656414 5.32102385329467 0.69700563252836 0.486878084773581 EHHADH-AS1 other 0.0144896540839961 1 0.00289139134088657 5.40054757942543 0.69700563252836 1.7173395931788e-09 19.2100470067899 3.61350259047564 5.31618465071068 3.66189405280907e-07 -3.89009523597852 5.5383819464082 -0.702388400370502 0.48349728189583 TH2LCRR other 1.91517711431299e-05 1 0.00411340558952043 5.31618465071068 -0.702388400370502 5.12428122937223e-09 109.526070276397 23.0540144632218 4.75084590803586 4.62808096693241e-06 -50.2876722033304 42.4279834013518 -1.18524775800983 0.237757154627637 NUTM2A-AS1 other 5.56138241823768e-05 1 0.0483958426712122 4.75084590803586 -1.18524775800983 7.96077710168912e-23 291.014121923937 37.6420586780195 7.73108942880083 1.35690562392914e-12 -77.6694320159088 60.5322685582486 -1.2831079003948 0.201407211222994 EXOSC6 essential 1.13918720325171e-18 1 1.83847142986159e-08 7.73108942880083 -1.2831079003948 1.27859038288267e-22 435.942578892454 50.843779184882 8.5741576625775 9.25819993717911e-15 -535.622208955749 151.563353118741 -3.53398231125251 0.000538876545022295 VPS52 other 1.82800067040736e-18 1 1.28837110325784e-10 8.5741576625775 -3.53398231125251 0.00545650290287576 -97.8842439442253 32.2492840062785 -3.03523774125244 0.00281150284297728 -236.04740610042 94.9932116996624 -2.48488709747729 0.0140012297285907 HLA-DQB1-AS1 other 1 1 1 -3.03523774125244 -2.48488709747729 2.9998752642843e-18 145.830870933362 17.3319781846438 8.41397729559622 2.89704255569608e-14 -143.023213551135 74.5588765329128 -1.91825869972705 0.0569780156485936 ZNF844 other 4.19262566936374e-14 1 4.00747896729439e-10 8.41397729559622 -1.91825869972705 0.368196987483168 -46.732577848461 59.3035751567161 -0.788022943388576 0.432096123083409 -164.491935234645 116.111008363523 -1.41667820780309 0.158932734899298 CKMT1A other 1 1 1 -0.788022943388576 -1.41667820780309 0.12195655214347 1.92699470182701 5.85804788847451 0.328948267155395 0.742638824406886 -13.9222764514303 10.6223765721632 -1.31065551638555 0.191912846666248 TINCR other 1 1 1 0.328948267155395 -1.31065551638555 0.0674368775012974 11.5295126173514 4.98496644440531 2.31285661517162 0.0220629850848973 3.63292496171518 21.9781311023427 0.165297265031235 0.868928215825811 C1GALT1C1L other 1 1 1 2.31285661517162 0.165297265031235 0.00633261325786033 187.087646262954 62.0508207914334 3.0150712573456 0.00303406507337324 -123.358851603503 245.719468317511 -0.502031249083214 0.616407028702196 NSUN5P1 other 1 1 1 3.0150712573456 -0.502031249083214 0.0178685261712011 -33.7925976077635 20.5961211704432 -1.64072629637944 0.102921949479187 -92.3825050778605 32.2774799054879 -2.86213500398318 0.00480180791303877 TSSC2 other 1 1 1 -1.64072629637944 -2.86213500398318 0.584233728641465 0.66996537316484 1.74017299191353 0.384999293908207 0.700755704125131 -4.02313992563536 5.37217201034882 -0.748885165606253 0.455039846067347 LGALS8-AS1 other 1 1 1 0.384999293908207 -0.748885165606253 0.363082088392234 -16.8125223042392 12.4304526154877 -1.35252696135069 0.17818941587367 -44.6795232997127 47.2582554104714 -0.945433192817622 0.345918778631461 LINP1 other 1 1 1 -1.35252696135069 -0.945433192817622 0.000170751875050344 17.1453364460965 5.33352591602158 3.21463450558907 0.00158563365071744 -13.6264802848924 11.5791287831935 -1.17681395034405 0.241050868115752 ENTPD3-AS1 other 1 1 1 3.21463450558907 -1.17681395034405 5.93630255711099e-09 7.73528336003545 1.56474405781748 4.94348153705387 1.95215064627808e-06 -2.23326138359855 2.79941217590723 -0.797760830941158 0.426214244633364 CFL1P1 other 6.41536217346985e-05 1 0.0209543850371489 4.94348153705387 -0.797760830941158 0.00476501283099705 -1157.94194866191 391.157038788454 -2.96029940365753 0.00355040710099602 -3218.15440025326 1194.30157822948 -2.69459109735423 0.00781474390772052 HLA-DPB1 other 1 1 1 -2.96029940365753 -2.69459109735423 1.76770870523403e-08 61.4565886079425 10.4701994352356 5.86966742974553 2.56380380032478e-08 -10.9201896845305 45.9141330789708 -0.237839396112481 0.812319768821624 OSER1-AS1 other 0.000185803862007149 1 0.000306630934518844 5.86966742974553 -0.237839396112481 0.00622482729957816 100.402676708057 31.4973568943367 3.18765403220579 0.00174584911701903 57.7795791847016 88.4549917928853 0.653208801601505 0.514621655354026 C1QTNF5 other 1 1 1 3.18765403220579 0.653208801601505 1.15560065148355e-11 144.903161524166 22.2541302965634 6.51129294172163 1.35166269640886e-09 21.3948487966704 39.3436112140118 0.543794739132915 0.587479652171467 AFG3L1P other 1.41826867956576e-07 1 1.69849934430737e-05 6.51129294172163 0.543794739132915 8.88127070631406e-07 216.358804690188 61.1036598481129 3.54084853882725 0.000564079672379122 -243.718676054101 134.901947117136 -1.80663571773712 0.0732638612588296 CPTP other 0.00813613209405431 1 1 3.54084853882725 -1.80663571773712 0.0276389601802097 5.72690870261612 5.75729202975635 0.99472263574903 0.321431575886301 -39.2766506495818 17.8932227810033 -2.19505737620842 0.0296564379680126 SLC44A3-AS1 other 1 1 1 0.99472263574903 -2.19505737620842 5.86770564503939e-06 16.6597551836123 3.68195717694251 4.52470096283046 1.21715716420091e-05 -13.6300644886705 12.1261075703318 -1.12402635467447 0.262785581195734 DNAJC27-AS1 other 0.0495410387610676 1 0.122665099008168 4.52470096283046 -1.12402635467447 0.0528487632257116 439.025584909593 198.134010948841 2.21580122870954 0.0283083130240773 -344.741311031212 743.602704759452 -0.463609544215863 0.643642388484698 HAGLR other 1 1 1 2.21580122870954 -0.463609544215863 0.150943600321477 40.6643367043428 25.0300226208907 1.62462245121598 0.106236235798347 -11.8955256225037 55.7501135613935 -0.21337222227187 0.831311720786216 MSL3P1 other 1 1 1 1.62462245121598 -0.21337222227187 4.23537753789979e-07 21.5894490533929 4.72114020948966 4.57293113430466 1.04309149243e-05 -21.4793993299298 14.795445977993 -1.45175747739396 0.148790487948554 MDC1-AS1 other 0.00399353748048571 1 0.105717322757781 4.57293113430466 -1.45175747739396 0.207443488377002 59.5263452287729 33.3906342985577 1.78272579959178 0.0766138943416676 4.75640451952216 133.266091943557 0.0356910332565065 0.971575243225162 PRR29 other 1 1 1 1.78272579959178 0.0356910332565065 0.0379084086844605 -1403.04502007264 556.067824319704 -2.52315447632514 0.0128266535380055 -829.624335691079 1750.54044477526 -0.473924688896627 0.636342540250103 C4B other 1 1 1 -2.52315447632514 -0.473924688896627 0.457778092681252 11.140072442025 12.1675788268283 0.915553751537014 0.361305087886251 -3.06834626430625 21.1577497943374 -0.145022334328174 0.884879246887558 ADM5 other 1 1 1 0.915553751537014 -0.145022334328174 1.02263368476626e-05 30.8903137789905 7.39365330004409 4.17794999649311 5.42972145210953e-05 -14.0696293286116 15.9478244105387 -0.882228758382494 0.379319886726242 PRKAR2A-AS1 other 0.0844695423616928 1 0.511479760788718 4.17794999649311 -0.882228758382494 6.82554717220663e-14 493.457806092239 70.1802868555648 7.03128796135879 6.13836896055935e-11 142.977035315102 111.182368070987 1.28596860991317 0.200371762441125 ATXN1L other 8.94556212389401e-10 1 8.04862938108542e-07 7.03128796135879 1.28596860991317 4.1721470528244e-13 96.5424951049839 14.8618292129028 6.49600353509427 1.07931157543992e-09 -64.6610248981507 41.2949136971704 -1.56583508982079 0.119439780267839 SMIM13 other 5.35787124523709e-09 1 1.36025637852694e-05 6.49600353509427 -1.56583508982079 0.0944017922655513 -2.96065494070459 2.96489688733802 -0.998569276843475 0.319539946666738 -19.7270892295939 9.01213918194149 -2.18894635683423 0.0300775359794501 HLA-DPB2 other 1 1 1 -0.998569276843475 -2.18894635683423 0.802312403085356 0.476511395853457 5.01269614973739 0.0950608976924367 0.924398610830932 -11.0826931909974 18.1420388540993 -0.610884657459169 0.542238987200346 LINC01117 other 1 1 1 0.0950608976924367 -0.610884657459169 0.00992703452892465 311.561925152659 119.104226377642 2.61587631798048 0.00980968042943695 -147.560547067452 464.199971207762 -0.317881422274815 0.751016988187724 HNRNPA1P10 other 1 1 1 2.61587631798048 -0.317881422274815 0.0886879407043634 6.03505590812934 3.59922307900582 1.67676628418274 0.0956572316584893 -5.77405056915481 8.94936500174293 -0.645191090991404 0.519782463644981 ZMIZ1-AS1 other 1 1 1 1.67676628418274 -0.645191090991404 2.37937196771757e-05 59.0640995839046 13.5562322681925 4.35697016806719 2.36454253824838e-05 -26.3911876147749 59.6218452020503 -0.442642919308162 0.658629418000106 SVIL-AS1 other 0.188945927956452 1 0.231299551091456 4.35697016806719 -0.442642919308162 0.209354285573837 4.20547566482489 2.99486373185699 1.4042293878317 0.162374262434517 15.3099384157995 11.073859696677 1.38252956377925 0.168920291588394 LINC00885 other 1 1 1 1.4042293878317 1.38252956377925 7.4395005275825e-06 235.425383488031 89.4833998529328 2.63093918955869 0.00937471799970766 -419.674868588178 171.386603653733 -2.44870287199392 0.0154520037711988 SH3BP5-AS1 other 0.0621793454095346 1 1 2.63093918955869 -2.44870287199392 0.00537466347462252 27.1647409309369 12.9451506714477 2.09844918922823 0.0374870366793562 -30.2882623389734 29.6591524913709 -1.02121132246734 0.30874557409396 NPIPA3 other 1 1 1 2.09844918922823 -1.02121132246734 0.700665414667183 40.8842555441655 55.9655913446149 0.730524855753167 0.466201355692184 -30.3386475065749 188.155319112206 -0.161242571561224 0.872117886120194 PCOLCE-AS1 other 1 1 1 0.730524855753167 -0.161242571561224 0.378644790580257 0.0673433714618674 1.94447973494393 0.0346331053246021 0.972416577818593 -8.53018764417457 6.4232723549674 -1.32801275934965 0.186113661820205 LINC00853 other 1 1 1 0.0346331053246021 -1.32801275934965 8.11710039770363e-05 27.391980484279 9.21805150107044 2.97155862940212 0.00346255828956311 -45.629396458258 26.3913509882414 -1.72895265871717 0.0859170076339072 LINC00240 other 0.602532362521541 1 1 2.97155862940212 -1.72895265871717 0.000151839279596153 156.223486831973 37.268185962454 4.1918725797215 4.79010875341237e-05 -143.081241336825 165.715814351221 -0.863413319344261 0.389336177250343 NDUFAF8 other 1 1 0.454246013086095 4.1918725797215 -0.863413319344261 4.99509209934266e-08 12.9365503552169 2.47768227782681 5.22123053104438 5.75307337758167e-07 -11.0654710010494 7.64001412568175 -1.44835740078713 0.149576793843922 POT1-AS1 other 0.000507851013740168 1 0.0063824596050891 5.22123053104438 -1.44835740078713 0.189224435782295 3.13064646502623 1.81242919572816 1.72732069887479 0.0860892982145497 -1.48524457310665 6.37926028150118 -0.232823949418339 0.816203306977574 PRRT4 other 1 1 1 1.72732069887479 -0.232823949418339 0.768201556320373 -1.183173783113 3.58335759662583 -0.330185796758634 0.741705428291056 -5.15878032720459 7.11950933641977 -0.724597733275649 0.469791216948679 TMEM233 other 1 1 1 -0.330185796758634 -0.724597733275649 0.442555878108059 3.05671431589325 2.61053669334149 1.17091413566023 0.243567275996477 -0.0526667136117138 6.74380132606315 -0.00780964786257414 0.993779674793633 CATIP-AS1 other 1 1 1 1.17091413566023 -0.00780964786257414 2.60830111958109e-05 326.073491464867 83.529052210859 3.90371353240947 0.000170238715618336 -153.905666931322 140.230691752231 -1.09751770463525 0.274999324892764 GOLGA2P7 other 0.206238369525277 1 1 3.90371353240947 -1.09751770463525 0.0199858786483959 14.7194513509718 6.12846478272374 2.4018170737419 0.0175130686496154 -12.0113620406241 16.8496575647308 -0.712854964231795 0.477021295914129 LINC01297 other 1 1 1 2.4018170737419 -0.712854964231795 0.000939457464505911 10.6372781096565 3.18646682668524 3.33826733125668 0.00105427523613444 -5.67585524530951 9.93934020283644 -0.571049499210196 0.568787821538845 TAF1A-AS1 other 1 1 1 3.33826733125668 -0.571049499210196 0.886424275439134 -1.48511083007681 4.10925330484908 -0.361406494051929 0.718287752300579 -5.53204739810584 12.8022971108202 -0.432113655090091 0.666259344546888 LHFPL3-AS2 other 1 1 1 -0.361406494051929 -0.432113655090091 0.0079128428441734 15.15580497974 13.5988871568859 1.11448861990636 0.266864078509143 -35.3138741052137 18.499129926244 -1.90894783949354 0.0581913404178605 PPP1R26-AS1 other 1 1 1 1.11448861990636 -1.90894783949354 0.507272099270643 3.80367656577681 6.06523431265999 0.627127720002074 0.531510243089113 -7.35282085803802 11.8334191437263 -0.621360637084866 0.535287037770032 LINC01671 other 1 1 1 0.627127720002074 -0.621360637084866 0.00742064389699493 12.7227170537466 4.00465132815213 3.17698496353671 0.00179626570474975 6.58202983595939 7.3604449292141 0.894243472950239 0.37257808788505 LINC01504 other 1 1 1 3.17698496353671 0.894243472950239 0.764763279423681 1.59119377490985 2.18652117979487 0.727728498408199 0.467870627297254 1.16435756310495 5.34855542722722 0.217695708485641 0.827950693305703 RAB6C-AS1 other 1 1 1 0.727728498408199 0.217695708485641 2.12990364270841e-10 79.673437633477 18.3989675682095 4.33032110840501 2.66235035644375e-05 -138.507047581856 44.1277764397724 -3.13877241856717 0.00203149549623484 NUTM2B-AS1 other 2.48453259921936e-06 1 0.259446042235443 4.33032110840501 -3.13877241856717 0.216406425959456 20.7985035144736 17.9116639736435 1.16117093001956 0.247346082628204 -58.5063109364371 58.8464291761285 -0.994220239962676 0.321655295762207 GBP1P1 other 1 1 1 1.16117093001956 -0.994220239962676 0.00118422953206368 9.50018315018315 7.00814865661178 1.35559098638986 0.177176171296988 -32.6761904761905 13.6286747834245 -2.39760585643529 0.0176770331705681 MKRN2OS other 1 1 1 1.35559098638986 -2.39760585643529 3.5515772502722e-17 9.65620540320985 1.12295478750648 8.59892625298961 8.27796853827841e-15 2.03869491953366 2.57005869703998 0.793248388405172 0.428845720844557 MTOR-AS1 other 4.90863491760121e-13 1 1.15245877989912e-10 8.59892625298961 0.793248388405172 0.112369889026267 -126.289552887961 72.7728625153376 -1.73539350415608 0.0847386489784464 -16.3046102992348 127.443866225135 -0.12793562202854 0.89837242877218 ZNF469 other 1 1 1 -1.73539350415608 -0.12793562202854 0.0973711170211282 10.1481869056827 8.4010307830099 1.2079692561306 0.228985798736629 -52.4581977011114 33.4921045229683 -1.56628550066588 0.119417450460727 SBDSP1 other 1 1 1 1.2079692561306 -1.56628550066588 0.00107496414968481 440.128061828684 117.268127103182 3.75317720766039 0.000255732849444914 -156.836453161025 532.364603388466 -0.294603458161515 0.768736343381138 MCRIP1 other 1 1 1 3.75317720766039 -0.294603458161515 0.0061551167557116 29.1559236544965 9.84718909153089 2.96083718749467 0.00354141815818184 4.26044362927724 15.4591151825542 0.275594274249615 0.783219810890633 FAM225B other 1 1 1 2.96083718749467 0.275594274249615 3.59313229576197e-09 657.983125178759 142.637658165059 4.61296920913653 8.19011181079801e-06 -519.463073696251 272.536011017347 -1.90603462550564 0.0584730254450723 FGD5-AS1 other 3.93483917708893e-05 1 0.0837602734890312 4.61296920913653 -1.90603462550564 0.0378646569944877 9.35954598451962 4.61447771019904 2.02830018310261 0.0442758604106431 -19.5780666882062 22.7641953247426 -0.860037721910013 0.391122703154223 PROSER2-AS1 other 1 1 1 2.02830018310261 -0.860037721910013 0.729341890391412 8.80872758733312 11.2798063744001 0.780928971203337 0.436100072251407 8.98452411430781 16.3481074073625 0.549575794336998 0.583444324740989 MIAT other 1 1 1 0.780928971203337 0.549575794336998 1.0651626354493e-10 46.5201471739042 9.31402806385044 4.99463248929407 1.61933588517923e-06 -75.1069996842351 27.8256379635157 -2.69920135461813 0.00774850612670585 TRAM2-AS1 other 1.26019391400007e-06 1 0.0174661568575432 4.99463248929407 -2.69920135461813 2.17954717016533e-07 38.5363368430698 8.92966772505412 4.31553984197506 2.88751582326284e-05 -38.0846230787439 25.1326964132801 -1.51534170677445 0.131804447366993 FAM229A other 0.00210762211354987 1 0.280175660331193 4.31553984197506 -1.51534170677445 1.51440926779767e-09 135.391042930996 22.0654077532135 6.13589580782969 6.623726104889e-09 -9.32653779875633 46.7715708957874 -0.199406126844381 0.842203092254452 ERCC6 other 1.69386676603169e-05 1 8.12863667591979e-05 6.13589580782969 -0.199406126844381 0.000578071021366518 7.08095781368841 3.28089551259032 2.15823935462604 0.0324689091259634 -32.1746293460028 14.5668187279519 -2.20876156605585 0.0286780941982892 LINC01529 other 1 1 1 2.15823935462604 -2.20876156605585 0.0122205616504068 6.03171966284616 2.90528526411425 2.0761195939515 0.0400182225273275 -5.18547919546895 6.50015213830766 -0.797747358082454 0.426592905852005 LINC00115 other 1 1 1 2.0761195939515 -0.797747358082454 1.32625828951456e-13 226.612155407684 36.3810995142632 6.22884295508552 4.38706533311674e-09 -249.060761706173 102.482088999968 -2.43028576150757 0.0162514843055487 NOL7 essential 1.72493153134264e-09 1 5.4153934471993e-05 6.22884295508552 -2.43028576150757 0.00564351440261851 20.9858388979509 7.63210798718888 2.74967793081248 0.00669418817448844 -35.775069451524 29.8442145256885 -1.1987271241711 0.232511936933037 CTAGE4 other 1 1 1 2.74967793081248 -1.1987271241711 0.0201005862654121 4.23558484349262 6.66924307959129 0.635092287527206 0.526292721942645 -21.4184514003295 11.7697499754393 -1.81978813866266 0.070696091571636 NTF4 other 1 1 1 0.635092287527206 -1.81978813866266 0.290739482627692 20.2280370809529 18.2776071282249 1.10671144964682 0.270238835670874 54.7885523337286 34.7300803181395 1.57755328613832 0.116832538068376 ELFN1 other 1 1 1 1.10671144964682 1.57755328613832 0.185606986563766 -17.9922723091077 15.7797914273957 -1.14020976715008 0.256065946571971 -103.114953583675 63.0957723556224 -1.63426089790129 0.10435852488618 ABHD11-AS1 other 1 1 1 -1.14020976715008 -1.63426089790129 2.25464668274259e-08 42.2144980302363 9.51325381783607 4.43744052650943 1.71895544182865e-05 -30.1621321803934 14.1476738560541 -2.13194992245926 0.0345869656748464 PIGBOS1 other 0.000235137102543225 1 0.170554758938238 4.43744052650943 -2.13194992245926 2.09372087140931e-07 4.98787587610219 1.06551605475889 4.68118321992894 6.35976860565255e-06 -4.51893064959483 3.89004086535538 -1.16166662665175 0.247228406199644 LINC01534 other 0.00202902489648276 1 0.0656836901591795 4.68118321992894 -1.16166662665175 0.182078863075305 -4.13363022868228 4.01836452894965 -1.02868472954661 0.305230423683232 5.40698341575366 8.86995493863041 0.609584090693085 0.543029901658983 UBXN10-AS1 other 1 1 1 -1.02868472954661 0.609584090693085 0.722543674547574 1.53076660197179 3.39401623849862 0.451019233381435 0.652618448994456 -5.14962569396534 10.9181122401429 -0.471658981030766 0.637846551044087 LAMP5-AS1 other 1 1 1 0.451019233381435 -0.471658981030766 5.82604558665974e-08 18.36108219831 4.11396985858117 4.46310566909267 1.56458601804886e-05 -7.40564915714025 9.16569936741795 -0.807974259276461 0.420368081789888 LINC01772 other 0.000590120157472765 1 0.155785829817125 4.46310566909267 -0.807974259276461 0.27048319351254 7.78520567036126 5.27820077390309 1.47497338654746 0.142358267052021 -0.761078326764368 12.150496697113 -0.0626376308505316 0.950140152097365 ZNF503-AS1 other 1 1 1 1.47497338654746 -0.0626376308505316 0.0450924947777587 4.98552927412205 3.29951994559661 1.51098625143197 0.132854551947649 -22.4238703467202 15.1589697624932 -1.4792476466443 0.141130114362959 LINC00937 other 1 1 1 1.51098625143197 -1.4792476466443 0.0333006633388779 16.7452141527001 11.9698076701558 1.39895432024784 0.163837486413044 -59.2981626319057 36.079652272929 -1.64353475979584 0.102312414727177 FTCDNL1 other 1 1 1 1.39895432024784 -1.64353475979584 5.64351887597224e-08 141.105789393709 24.2499789426026 5.81880049164962 3.61083590348448e-08 234.68728156815 108.148751025236 2.17004153393678 0.0316209881216078 BAIAP2-AS1 other 0.000572365684401105 1 0.000429042065794747 5.81880049164962 2.17004153393678 1.86286750519999e-05 6.52634675732215 5.34981778041688 1.21991944869823 0.224372488974959 -68.1961397650467 16.9820990445183 -4.01576622455632 9.25814970369791e-05 AP4B1-AS1 other 0.149532374642403 1 1 1.21991944869823 -4.01576622455632 1.43814139171205e-15 119.686623543662 13.6804103130548 8.74875978167472 4.6232123565918e-15 17.1180492251595 27.9037929269175 0.61346675235131 0.540515839962966 TEX22 other 1.94709963023895e-11 1 6.44938123744556e-11 8.74875978167472 0.61346675235131 0.0319686067302016 4.68405787517064 2.43346570111152 1.92485058368858 0.0560795711272889 -12.1043708696863 8.99112343357517 -1.34625789080878 0.180184892140701 LEMD1-AS1 other 1 1 1 1.92485058368858 -1.34625789080878 0.0115070315941848 15.5911463321203 5.46909045212645 2.85077499971833 0.00496345286810685 3.65210208772266 8.12995105743686 0.449215753197174 0.653911694871533 GAS1RR other 1 1 1 2.85077499971833 0.449215753197174 0.266932466179693 6.17744536940681 15.5367852045969 0.397601259723863 0.691497005351053 -45.6182448838015 35.1816585360606 -1.29664850328314 0.196770162735108 ZNF32-AS1 other 1 1 1 0.397601259723863 -1.29664850328314 1.45035359281838e-05 19.9804700096743 10.2585269741828 1.94769386091768 0.0534383948088302 -46.081909061593 16.8524647435511 -2.73443141776797 0.00705102119495444 TMEM191A other 0.11771069759314 1 1 1.94769386091768 -2.73443141776797 0.0368780227003317 0.331044034625529 2.73739335739172 0.120934038848168 0.903902997876582 -19.3763432442604 8.11413340048429 -2.38797445000152 0.0181695177823834 CFLAR-AS1 other 1 1 1 0.120934038848168 -2.38797445000152 1.72858255252199e-05 7.78833865814693 2.43383028756444 3.20003358407575 0.00167091648986206 -13.226318232708 6.92677432045387 -1.90944841290013 0.0580759262440521 ZNF192P1 other 0.139200228531085 1 1 3.20003358407575 -1.90944841290013 0.240447215917794 -14.7969543147208 19.3257757142823 -0.765659010716215 0.445141132475253 -71.6656517937124 42.2369818122501 -1.69675125254634 0.0919193169963734 CROCC2 other 1 1 1 -0.765659010716215 -1.69675125254634 0.00357279630867102 1.77876974305899 1.75583397413205 1.0130626068665 0.312661578049576 -14.5854160104396 5.33910878388027 -2.73180723615814 0.00705494707367558 ST7-AS2 other 1 1 1 1.0130626068665 -2.73180723615814 3.82299973963594e-05 10.3564933517265 2.24821835175728 4.60653358853314 8.48865666603443e-06 4.15481340777282 6.82270636739579 0.608968521293508 0.543436798826046 LINC01876 other 0.295123508421571 1 0.0867447850283957 4.60653358853314 0.608968521293508 0.0438688607634064 12.5006437373551 4.95010269925192 2.52533017936058 0.0125907546611382 12.2194531297897 8.49134273044125 1.43904839525359 0.152206482467915 MRPL23-AS1 other 1 1 1 2.52533017936058 1.43904839525359 0.0174072826952835 27.3822508676252 14.4513782643826 1.89478473033347 0.0600074702588442 -67.4161931276458 47.0808312687678 -1.43192444378882 0.154205170272879 SLC16A1-AS1 other 1 1 1 1.89478473033347 -1.43192444378882 1.8535015479137e-08 184.450930460333 38.3247318010401 4.81284334663831 3.50319449854188e-06 -184.441741608049 102.227034016448 -1.80423645645801 0.0731358300455962 TMEM185B other 0.000194524987453543 1 0.0369376827926256 4.81284334663831 -1.80423645645801 0.81232429350239 0.348058637083998 3.41567019153717 0.101900540030582 0.918972624831288 -8.99373181635407 14.4392975159574 -0.622864914751895 0.5343254529912 ADIPOQ-AS1 other 1 1 1 0.101900540030582 -0.622864914751895 0.176610858706828 6.98205783365781 9.83395345898973 0.709995004834515 0.478795047637116 -23.2995013563558 18.5266154341595 -1.25762319832019 0.210456786054234 LINC00323 other 1 1 1 0.709995004834515 -1.25762319832019 1.29935983698894e-06 17.1689450682049 3.58291360980651 4.79189479233134 3.87593052238721e-06 -8.50139058522303 15.570973586828 -0.545976816274009 0.585877075251025 PLCG1-AS1 other 0.0117319199681732 1 0.0407437816513344 4.79189479233134 -0.545976816274009 0.239404462075613 -0.942100574321659 2.01829471341789 -0.466780479609073 0.641334205434227 4.0669879307733 3.21350608582756 1.26559210474498 0.207621434167186 KIF4B other 1 1 1 -0.466780479609073 1.26559210474498 0.00253933974769279 19.2693250039402 5.93633380235867 3.24599755429588 0.00143429348704057 -4.30815769489775 16.5171665303862 -0.260829100861346 0.79457051551656 TEX41 other 1 1 1 3.24599755429588 -0.260829100861346 1.44645108177478e-10 62.5008290774027 8.88213148191267 7.03669262323775 6.67801294900433e-11 42.1197955756938 36.2649164759918 1.16144747234088 0.247317192142971 LINC01535 other 1.70030324662626e-06 1 8.74752916190078e-07 7.03669262323775 1.16144747234088 0.00030682274446753 12.916633433476 4.21047614345084 3.06773699539115 0.00253848361951562 -3.879536330524 7.49631654398943 -0.517525681814308 0.605513053705925 ENTPD1-AS1 other 1 1 1 3.06773699539115 -0.517525681814308 0.000102766906523484 10.7672801554348 4.92508592191383 2.18621163694354 0.0302807744702403 -20.7103893857128 10.5307296028129 -1.96666234599556 0.0509850974349635 LENG8-AS1 other 0.752767590284521 1 1 2.18621163694354 -1.96666234599556 1.59889232907748e-12 22.5178668480583 3.17525301793894 7.09167638636706 4.50262337113684e-11 -23.6756382604178 14.5966286503393 -1.62199360054744 0.106850240020339 FAM66C other 2.01748234082997e-08 1 5.91959894603361e-07 7.09167638636706 -1.62199360054744 0.000145412635899868 -86.1975338268145 47.5025771879867 -1.81458646939715 0.0722170531253631 -356.411779545777 87.0129731234179 -4.09607632921872 7.88918617427034e-05 HSBP1L1 other 1 1 1 -1.81458646939715 -4.09607632921872 1.19436620610087e-16 64.9919085340018 9.5113360524522 6.83309980591483 1.81877815148486e-10 -74.9994047847479 27.0471280832726 -2.77291565129725 0.0062421193254006 SRRM5 other 1.64117860380321e-12 1 2.35186202768507e-06 6.83309980591483 -2.77291565129725 0.71617585556861 1.64403811414941 4.81432765481097 0.341488621470646 0.733201277206536 7.63053360728454 9.32842413672277 0.817987421610235 0.414628201723385 FAM30A other 1 1 1 0.341488621470646 0.817987421610235 1.79593848777034e-05 41.5949742696659 10.9896798526797 3.78491228382086 0.00022177624572342 -8.70934252175967 16.3430191374489 -0.532909032811618 0.594885179158375 CACTIN-AS1 other 0.144429373186491 1 1 3.78491228382086 -0.532909032811618 0.000500409511447635 16.106763839757 4.29077378082784 3.75381333588961 0.000245300243156746 4.49181375363472 7.77332801073761 0.577849506341428 0.564198876911415 ATE1-AS1 other 1 1 1 3.75381333588961 0.577849506341428 0.00644421861974376 63.2181272257522 22.5197325405223 2.80723259532487 0.00574324927076774 15.1417964294858 37.4060962212709 0.404794885302025 0.686273738012457 ERVMER34-1 other 1 1 1 2.80723259532487 0.404794885302025 0.0245952403585969 1.14768858867359 3.16491169158954 0.362628945295208 0.717376075331967 -26.5511815240092 10.4638756179945 -2.537413716802 0.0121551965040878 LINC01359 other 1 1 1 0.362628945295208 -2.537413716802 2.05514485465767e-05 -56.5837720829557 180.471074583663 -0.313533746133508 0.754362708907621 -1212.08004562065 299.769030066647 -4.04337981595754 8.84254799064106e-05 DANCR other 0.164308831129881 1 1 -0.313533746133508 -4.04337981595754 0.844090800677259 -0.628677993848389 1.28751978427876 -0.488286084241074 0.626024188260263 -2.05185160182439 4.22470987159541 -0.485678700831009 0.627867818185797 LTA other 1 1 1 -0.488286084241074 -0.485678700831009 0.000795796382541449 15.2478440987487 3.94198900924001 3.86805850117994 0.000162682103955498 14.9491191932856 16.2517174837318 0.91984857651198 0.359119024121285 SLC8A1-AS1 other 1 1 1 3.86805850117994 0.91984857651198 0.549745454522252 30.393480728688 34.2857100437944 0.88647663093065 0.376716597214278 90.6205808422077 137.223878252413 0.660384927144514 0.509974585839816 LINC00511 other 1 1 1 0.88647663093065 0.660384927144514 0.0231638847525023 -37.6006416640813 16.0341323643501 -2.34503749935866 0.0203093719039829 -68.77193168645 28.3769080822647 -2.42351744196655 0.0165379126408066 ITGB2-AS1 other 1 1 1 -2.34503749935866 -2.42351744196655 0.00591503262908807 138.049969477631 63.5073458996097 2.17376379885023 0.0312404390858289 -131.9215902154 104.767173399907 -1.25918821644489 0.209855330439972 C14orf132 other 1 1 1 2.17376379885023 -1.25918821644489 5.81068052813715e-13 61.7712377698403 10.068926565805 6.13483844242357 6.73590589227362e-09 -34.0242489344448 22.8909762191121 -1.48636076542849 0.139201960588468 ZNF717 other 7.42953612327616e-09 1 8.2642829392305e-05 6.13483844242357 -1.48636076542849 1.43222755176188e-05 23.7553210637627 6.51355689026107 3.64705819938123 0.000365284832281151 -36.6605543805967 19.806308181437 -1.85095344598121 0.0661428965227717 ST7-AS1 other 0.116339844029618 1 1 3.64705819938123 -1.85095344598121 3.07917119597443e-05 6.22999674743862 2.15768350355265 2.88735430251048 0.00444796485258704 -5.50493305144465 3.67659057551642 -1.49729292353186 0.136377217788256 SMIM2-AS1 other 0.241068312932838 1 1 2.88735430251048 -1.49729292353186 2.52016593484947e-07 17.2945156786887 3.94542063940817 4.38344026133623 2.12976439414661e-05 -4.86932880685352 7.05857198936444 -0.689846163528603 0.491309356116298 KLLN other 0.00242238349657731 1 0.209547518740085 4.38344026133623 -0.689846163528603 3.69797276439705e-08 127.743144635932 22.6593999827268 5.63753430070124 7.88095517318513e-08 -2.83635251708376 47.8168874940945 -0.0593169623897846 0.95277556873558 PARG other 0.000379744823175933 1 0.000920653183331487 5.63753430070124 -0.0593169623897846 0.000260216037243309 18.4577757268112 4.80823093047902 3.83878727825005 0.000184586567054871 2.31160826120941 8.87603437334285 0.260432549489872 0.794902174126741 RBM26-AS1 other 1 1 1 3.83878727825005 0.260432549489872 2.93293852685686e-13 183.243751041571 29.3656190556182 6.24007791882435 4.88162454520924e-09 -88.8784980404421 65.3239687431625 -1.3605801936176 0.175832845402605 TP73-AS1 other 3.77967787956044e-09 1 6.01562592706135e-05 6.24007791882435 -1.3605801936176 9.56330432911904e-24 96.1989619377163 8.06190906665423 11.9325287772862 9.85059158347407e-24 55.0924644367551 36.2111634976766 1.52142210068146 0.130178326588176 HPN-AS1 other 1.37242980427187e-19 1 1.42104634183197e-19 11.9325287772862 1.52142210068146 0.419055951506823 8.80982790882283 7.57492675656232 1.16302483072733 0.246691199618669 -6.27418348831937 21.4519600365981 -0.292476001149327 0.770332330364215 LINC01806 other 1 1 1 1.16302483072733 -0.292476001149327 0.149087480964575 5.92267917864279 3.37667515145837 1.75399732369423 0.0815008619963105 0.556527064120273 6.35176863475426 0.0876176536209436 0.93029900891785 FGF7P6 other 1 1 1 1.75399732369423 0.0876176536209436 0.0305198935295516 13.0339363528325 5.0265044228201 2.59304185502334 0.0104612308202358 4.96334345701835 9.79812522304417 0.506560525001771 0.61321197848024 LINC00310 other 1 1 1 2.59304185502334 0.506560525001771 0.953002379076979 -1.65208338357893 46.5882626471201 -0.0354613649384725 0.971757188174638 -52.6408910755774 170.412809609975 -0.308902195768365 0.757808080564894 AKR1B15 other 1 1 1 -0.0354613649384725 -0.308902195768365 0.241265547721995 8.82410552873623 6.76737177345613 1.30391913199557 0.194258628382362 -4.6772950314879 17.6236704040188 -0.265398462650624 0.791066911978229 NCAM1-AS1 other 1 1 1 1.30391913199557 -0.265398462650624 0.0179366316250125 383.595354812844 162.915829004099 2.35456159881918 0.0199238088542727 -98.0412308196961 243.462240518872 -0.402695837394532 0.687781883127945 SCAMP4 other 1 1 1 2.35456159881918 -0.402695837394532 0.152121372039576 28.7676327259071 39.6674026168653 0.725220983177659 0.469389195255793 -178.926587373582 130.159761008951 -1.3746689912966 0.171180551936276 LTB other 1 1 1 0.725220983177659 -1.3746689912966 0.0239905509345142 9.81759890006875 3.5522991177913 2.7637309175059 0.00642125503761357 11.9795762764828 16.5220390628988 0.725066454017992 0.469525999814254 SLC2A1-AS1 other 1 1 1 2.7637309175059 0.725066454017992 6.11689960627483e-07 51.3131627549857 10.7536124588383 4.77171396601816 4.27272824501091e-06 -14.8023961208297 23.1329881067107 -0.639882580345755 0.523218619473846 DNAJC9-AS1 other 0.0056801529743868 1 0.0448166465619194 4.77171396601816 -0.639882580345755 0.00161919627149934 178.924548444307 56.948640987338 3.14185809076794 0.00200703993793158 -151.308837118538 174.06482092472 -0.869267186297091 0.386027971692361 CERS6-AS1 other 1 1 1 3.14185809076794 -0.869267186297091 0.014909819560425 31.107178772171 12.4022256545549 2.5081932580985 0.0131573933481467 -22.7056138254237 40.4785336105009 -0.560929752147281 0.575650228752732 LINC01132 other 1 1 1 2.5081932580985 -0.560929752147281 7.73706226205525e-07 8.85843470856755 2.03662064662687 4.34957522562646 2.49830198703676e-05 -2.38682897216156 4.06314842787854 -0.587433369597029 0.557790071928654 SLC9A7P1 other 0.00712041839976944 1 0.243884239974528 4.34957522562646 -0.587433369597029 7.71453040498097e-08 15.7725871526938 3.61276243239889 4.36579693456919 2.33051298083506e-05 -8.69765683666586 7.86744608158784 -1.10552481027115 0.270679017227668 DPY19L2P3 other 0.000774847433876289 1 0.228157220823752 4.36579693456919 -1.10552481027115 0.00174270044459984 2.94770677103819 1.0394340317686 2.83587671843171 0.00519280923365541 -3.87488957810778 3.34372514083612 -1.15885409682293 0.248333033226045 SNAP25-AS1 other 1 1 1 2.83587671843171 -1.15885409682293 0.0495659420407479 31.3032654072706 20.2133951610682 1.54863965988069 0.123507738573108 -29.2759440706075 41.7600979453837 -0.701050656272317 0.484322534909178 TARID other 1 1 1 1.54863965988069 -0.701050656272317 0.00151636638446675 180.103462929249 49.4635892297184 3.6411321081617 0.000371616686796831 96.6059317303024 152.773207014643 0.632348653393412 0.528109120988223 POLR2J2 other 1 1 1 3.6411321081617 0.632348653393412 0.00953024202617084 29.4879956914879 10.2434987128474 2.87870350923207 0.00460226011314737 -18.7677739248929 38.3538476300174 -0.489332233520281 0.625351045847586 MELTF-AS1 other 1 1 1 2.87870350923207 -0.489332233520281 0.000132862484667698 40.0035706050463 10.0643835508685 3.97476610493387 0.000107996415485478 -11.641078495082 30.5945612163009 -0.38049503023693 0.704102299768866 RNF144A-AS1 other 0.958469964392775 1 0.983847345072703 3.97476610493387 -0.38049503023693 0.891658521431201 1.21045197740112 8.54366841862921 0.141678248509945 0.887526828857869 -14.0861581920904 36.4664899955561 -0.38627677612534 0.69984645012751 NACAP1 other 1 1 1 0.141678248509945 -0.38627677612534 2.42360947121638e-06 7.83755500100793 1.90978337674311 4.10389738252612 6.54780411522177e-05 -12.774021451262 6.26846256816723 -2.03782367882861 0.0432679885563551 EFCAB14-AS1 other 0.0213132216898769 1 0.611368470238256 4.10389738252612 -2.03782367882861 0.060736814083116 23.8739765434831 14.5812438850188 1.63730726484947 0.103621423821312 -86.6431051798389 58.8355161132525 -1.47263270391067 0.142904262977348 LINC01320 other 1 1 1 1.63730726484947 -1.47263270391067 8.50092139043701e-06 75.920322344668 15.2792486824145 4.96885180172818 2.09640347358834e-06 31.490867687661 52.9175592426808 0.595092973643084 0.552823793945819 PCAT6 other 0.0707531687326072 1 0.0224587704125519 4.96885180172818 0.595092973643084 1.72855120490606e-05 10.6489001412511 2.29504683348376 4.639948948269 7.43461426287137e-06 0.169860648763826 6.31002291931819 0.0269191809500084 0.978559274075772 BMS1P17 other 0.139200228531085 1 0.0762717077227974 4.639948948269 0.0269191809500084 0.00365593181046163 107.714564369311 93.7193507466341 1.14933109876649 0.25239325512843 -329.478381014304 140.617304956908 -2.34308559046322 0.0205432282659438 C19orf24 other 1 1 1 1.14933109876649 -2.34308559046322 0.0177178994379908 -1.00816534830315 3.00585722287415 -0.335400278040871 0.737859677539448 -16.9404577305828 6.22341735234645 -2.7220507273541 0.00737099458827094 CYP4F29P other 1 1 1 -0.335400278040871 -2.7220507273541 1.91710743170609e-40 138.303358640141 7.38423110859297 18.7295544527579 2.52104131532308e-41 157.449864250301 40.8530578699697 3.85405334287203 0.000170978136626919 GUSBP11 other 2.79245868502309e-36 1 3.6729050922942e-37 18.7295544527579 3.85405334287203 1.80080702418945e-06 10.4664169465254 2.53875942998284 4.12265015066678 6.12159113828738e-05 -0.543055196762249 5.19589953342976 -0.104516107994063 0.916896671532197 TSTD3 other 0.016054194620649 1 0.573348226011996 4.12265015066678 -0.104516107994063 0.13128770874687 796.214140970091 468.260429555216 1.70036605853368 0.0912824870889645 -1266.47335997085 1716.97707964783 -0.737618093440491 0.461981064527861 OST4 other 1 1 1 1.70036605853368 -0.737618093440491 0.000865744631007725 54.6987725631767 17.4112260890884 3.14158074125845 0.0020946759974457 -11.7390613718412 26.984238407913 -0.435034007422601 0.664281966208091 CCDC183-AS1 other 1 1 1 3.14158074125845 -0.435034007422601 0.0358017658282701 254.997614788313 111.485755228629 2.28726633519571 0.0237960363655074 45.5859988073942 250.703366678914 0.181832415779952 0.855997464288734 FNDC10 other 1 1 1 2.28726633519571 0.181832415779952 0.00264241899409682 33.5037771536654 16.6598962123742 2.01104356993415 0.0460213815674826 -40.4203267037313 26.1543931047284 -1.54545076010285 0.124237865551666 ZNF883 other 1 1 1 2.01104356993415 -1.54545076010285 1.02684041167027e-05 9.48666642458729 2.75975303023885 3.43750557410068 0.000752824216701338 -4.24524906023198 5.67448052111011 -0.748129990831561 0.455508118522473 HDAC2-AS2 other 0.0847964811957306 1 1 3.43750557410068 -0.748129990831561 0.00630224408118139 3.26991419624763 3.91385716607685 0.835471009159312 0.404755337265861 -19.4017213001563 9.19145366956648 -2.11084361599915 0.0364116820122352 SNHG26 other 1 1 1 0.835471009159312 -2.11084361599915 0.236116780947859 8.72657073657215 11.0476426088706 0.789903425149294 0.430831098980251 -14.8175523578857 16.2218644434069 -0.913430907376872 0.362481810929274 PROB1 other 1 1 1 0.789903425149294 -0.913430907376872 0.000201202024302214 9.62660642541244 3.12555732474873 3.07996476314391 0.00245763216857612 -7.85509702910727 6.1919551068635 -1.26859721905933 0.206524147052044 TTC3-AS1 other 1 1 1 3.07996476314391 -1.26859721905933 1.95878567608298e-05 7.72835936993582 2.34227202912275 3.29951400770059 0.00119696164460704 -3.70386983859468 4.06175237287706 -0.911889622648541 0.363216045560213 TNKS2-AS1 other 0.156859556940725 1 1 3.29951400770059 -0.911889622648541 0.000197719475108884 102.310548577702 80.1773233852045 1.27605343079564 0.203845453851136 -226.452003487133 112.710909639377 -2.00914005761887 0.0462581341418177 DHFR essential 1 1 1 1.27605343079564 -2.00914005761887 0.181446743130612 -17.755318884834 15.0499751013298 -1.17975735941684 0.239964404297308 -52.9433976316378 29.2800223706908 -1.80817476712839 0.0725825252075314 SRGAP3-AS2 other 1 1 1 -1.17975735941684 -1.80817476712839 0.000937962491359917 19.913413968887 6.20981235132256 3.20676581549937 0.00163473137247205 -17.346640394274 21.7020791848836 -0.799307764315811 0.425351118962234 SAPCD1 other 1 1 1 3.20676581549937 -0.799307764315811 0.000464569535408912 16.2089575911375 4.64237313935841 3.49152407713992 0.000625832446718887 -17.6243594748914 16.275768182506 -1.08285884127023 0.280552745229907 WEE2-AS1 other 1 1 1 3.49152407713992 -1.08285884127023 0.0105992512831316 10.9270094917698 4.27665970330466 2.55503365940627 0.0116134840260609 -11.3007329088069 13.8031634347671 -0.818706013459417 0.414252940305205 LINC00954 other 1 1 1 2.55503365940627 -0.818706013459417 0.000500968782912739 30.9710788030146 9.92151186717121 3.12160880495373 0.00225396585633212 -12.1518864558713 22.1979360771307 -0.547433167374093 0.585097896579608 LINC01128 other 1 1 1 3.12160880495373 -0.547433167374093 0.00737227246735677 24.4033748493371 10.1344329829297 2.40796647335295 0.0175770011789942 -28.1178901452103 34.598220920128 -0.812697572228413 0.418014379942675 LAMA5-AS1 other 1 1 1 2.40796647335295 -0.812697572228413 2.78084175459286e-06 30.7134762732599 6.48135368445829 4.73874406004228 4.87555866782943e-06 -0.287038825574603 12.5616301448483 -0.0228504439523179 0.981799344156792 UBAC2-AS1 other 0.0242879680872755 1 0.0508667035814644 4.73874406004228 -0.0228504439523179 2.19970152425076e-16 61.0596674348199 9.07552788970148 6.72794664695018 3.23700630647862e-10 -29.1369346166011 15.3693589955248 -1.89578073002818 0.0598745925109689 MED4-AS1 other 3.01227126730899e-12 1 4.14725247986041e-06 6.72794664695018 -1.89578073002818 0.00329537182434026 1986.82367908007 827.737550399268 2.40030632671153 0.0178208150985244 -3251.49624954565 2292.94895655787 -1.41804126962631 0.15860867064823 RPL41 essential 1 1 1 2.40030632671153 -1.41804126962631 0.0405330813401904 1223.7991598577 486.959599043522 2.51314310727516 0.0129683942074974 2604.84302114107 1919.45298012728 1.3570757127733 0.176692652817452 VIM-AS1 other 1 1 1 2.51314310727516 1.3570757127733 0.240822977823523 -3.77276171331375 3.64432113687719 -1.0352440335559 0.302243532237112 -22.1576233183856 14.4676868957592 -1.53152494092753 0.1277744380187 EPHA1-AS1 other 1 1 1 -1.0352440335559 -1.53152494092753 0.267656121200811 32.0287527265516 27.5290113119297 1.16345452307152 0.24649254197341 -63.8034106682531 89.1298984963915 -0.715847451243717 0.47519843843626 PGA4 other 1 1 1 1.16345452307152 -0.715847451243717 0.943620626705817 -0.601367445963842 9.43440285236945 -0.0637419723721897 0.949256254757298 3.95582267313629 15.1114685027005 0.261776191534884 0.793834947932396 ORM1 other 1 1 1 -0.0637419723721897 0.261776191534884 0.00509162703964941 -500.804107072164 249.310012222528 -2.00876050908521 0.0462876857699158 -2431.72845095459 748.624119192557 -3.24826356593663 0.00142186572449742 HLA-DRB6 other 1 1 1 -2.00876050908521 -3.24826356593663 0.0224763266728574 7.20374992923208 4.09961883444253 1.75717553756718 0.0808371504675982 -7.693901604245 8.14756431491487 -0.944319223127899 0.346457508787623 LINC00858 other 1 1 1 1.75717553756718 -0.944319223127899 0.0032709915883639 45.7283862810179 13.3017009109754 3.43778488082578 0.000750967127309732 40.4347289873606 20.8622426188482 1.93817748772749 0.0543956884495679 RALGAPA1P1 other 1 1 1 3.43778488082578 1.93817748772749 0.103494643197673 0.558328358208965 8.10302630638226 0.0689036832780863 0.945163220001635 -23.3401671641791 12.658348819131 -1.84385558477456 0.0672885093705565 PATL2 other 1 1 1 0.0689036832780863 -1.84385558477456 1.04368285406932e-13 69.1432499631094 9.92990237996774 6.96313491486046 8.72676882340802e-11 -30.5735075947138 21.8366847952942 -1.40009840693869 0.163469514754873 ACVR2B-AS1 other 1.36075370513558e-09 1 1.13945420527239e-06 6.96313491486046 -1.40009840693869 0.125288400406514 18.6715107122785 9.21767489809228 2.02562044319255 0.0445533250563208 -6.30514090552567 37.5696051694658 -0.167825583396072 0.866943582312516 MBNL1-AS1 other 1 1 1 2.02562044319255 -0.167825583396072 1.60676424436355e-08 30.7471339532032 4.94515777390432 6.21762446396682 4.42141224468832e-09 26.256738530704 14.7670070847781 1.77806771405762 0.0773407584431527 ZNF492 other 0.000169208342573925 1 5.45602270994538e-05 6.21762446396682 1.77806771405762 0.269270930909338 -79.6455675846424 49.0583002962725 -1.62348811727368 0.106835277009534 -78.2004508514489 148.707868971815 -0.525866259748975 0.599850329095194 C2-AS1 other 1 1 1 -1.62348811727368 -0.525866259748975 3.63702185180044e-05 30.8179258249431 20.1749234948038 1.52753619278311 0.128665813580998 -141.014582471981 43.0341621642145 -3.27680557446156 0.00129571266159674 ZNF688 other 0.28176008285898 1 1 1.52753619278311 -3.27680557446156 3.07431313947843e-11 172.763274980249 30.3106738157722 5.69975039256142 5.99436226170698e-08 -124.864126367001 91.0737390330557 -1.37102229130705 0.172375712495916 PET100 other 3.71254054723416e-07 1 0.000705056889221975 5.69975039256142 -1.37102229130705 1.43127007821026e-07 2194.70982399513 422.713885890322 5.19195109801662 6.40416525362457e-07 89.7868200677445 757.865916760616 0.118473226044423 0.905845122909356 EMX2OS other 0.00140650910585723 1 0.00708300677050877 5.19195109801662 0.118473226044423 0.260297043137243 42.7909577632362 35.7535080697309 1.19683242494079 0.233260020300199 -80.5798929208805 115.758118191629 -0.696105760699105 0.48743978944331 PGA3 other 1 1 1 1.19683242494079 -0.696105760699105 0.06082026941239 1.25907379451725 9.95708857990841 0.126449994334472 0.899539610468189 -59.1268304717374 27.7064602546311 -2.13404490968327 0.034412218161279 STEAP3-AS1 other 1 1 1 0.126449994334472 -2.13404490968327 0.00016104916264715 30.4000300102893 20.984605583712 1.44868245862507 0.14944626440179 -74.5496813193097 31.2034411525674 -2.38914935550869 0.0180896607006912 LINC01315 other 1 1 1 1.44868245862507 -2.38914935550869 0.141680647901057 2.94095500090358 6.38416402738267 0.460664072584816 0.645734572013423 -17.4905072187305 13.0463343395532 -1.34064533098035 0.182146767957931 KIF25-AS1 other 1 1 1 0.460664072584816 -1.34064533098035 0.000305677462902249 12.9959818839579 3.14933888146651 4.1265746155289 5.94106500296414e-05 4.36922482118697 12.4439721249237 0.351111749313226 0.725972253981842 TOB1-AS1 other 1 1 0.556856022727829 4.1265746155289 0.351111749313226 0.854765356897231 -3.76896048487087 6.81295790730458 -0.553204721965175 0.580963594148207 -2.92475105699696 18.948766535254 -0.154350471918871 0.877545114519545 ANKRD66 other 1 1 1 -0.553204721965175 -0.154350471918871 0.025054577472814 20.0318723911747 8.08281692450544 2.47832810989968 0.0143632001340693 -0.0117769827071644 16.9151903493747 -0.000696237078266148 0.999445453556609 PRRT3-AS1 other 1 1 1 2.47832810989968 -0.000696237078266148 2.66237386334931e-09 9.81708882922845 1.56877049140281 6.2578234885397 3.64463852752589e-09 -7.28812108478269 5.88980067641011 -1.23741387615597 0.217804761048406 LINC02028 other 2.93792955820596e-05 1 4.51279142478256e-05 6.2578234885397 -1.23741387615597 0.00518358592854626 30.5728095378749 19.9745651346055 1.53058699059776 0.127936470511312 -234.629199001104 81.3527472765419 -2.8840968111812 0.00449180038808039 HOXB-AS1 other 1 1 1 1.53058699059776 -2.8840968111812 0.138924046781266 0.726699139388716 2.64110675850723 0.275149475517397 0.783563173713869 -6.21356282966967 4.07657641667737 -1.52421105225695 0.129467809544095 MIRLET7DHG other 1 1 1 0.275149475517397 -1.52421105225695 5.71729025433536e-06 10.210699015611 2.16925048312307 4.70701705268757 5.50852616771206e-06 -6.47036889728548 7.69901582145845 -0.84041506698187 0.401961944842595 TPI1P2 other 0.0483339718101511 1 0.0572115527778575 4.70701705268757 -0.84041506698187 0.0759048005347879 30.259108950631 14.1893235432052 2.13252653366418 0.0350012826208443 58.2335548320921 31.7465423825168 1.83432747196312 0.0690827330424347 FAM41C other 1 1 1 2.13252653366418 1.83432747196312 0.0062893454937094 11.3365768482566 4.69946743582694 2.41231096992626 0.0170592873126581 -9.37871780248284 8.21330845836926 -1.14189280118002 0.255318132800911 GOLGA6L17P other 1 1 1 2.41231096992626 -1.14189280118002 0.0420108989398234 15.7756251223653 6.36518658803544 2.47842304450565 0.0142612393130753 11.1822344563182 26.7678093289932 0.417749331627458 0.676704820180658 LRRC37A6P other 1 1 1 2.47842304450565 0.417749331627458 0.000495216997647075 14.4820793359922 17.07505860614 0.848142291633752 0.397747075309222 -74.9989112859761 32.4450653013775 -2.31156604523129 0.0222006106619159 PSMG3-AS1 other 1 1 1 0.848142291633752 -2.31156604523129 2.84445100590414e-14 9.03746633918265 1.41354271242911 6.39348656373612 1.76594087712652e-09 -3.28287811085138 2.90291605788394 -1.13088978302887 0.259826043444401 PPP5D1 other 3.76036422980528e-10 1 2.21148776042554e-05 6.39348656373612 -1.13088978302887 4.19892205273548e-19 163.584003845959 15.8202970870435 10.3401347614345 4.97785405067711e-19 61.6542432063155 28.4543221676845 2.16677954382396 0.0319198262803035 THAP7-AS1 other 5.90200483732499e-15 1 7.10588665734158e-15 10.3401347614345 2.16677954382396 0.0107571547118963 5.61912502253497 2.63486723773961 2.13260271411454 0.034542714202133 -2.58085547178622 3.85004565242724 -0.670344121805188 0.50364245233175 CCDC192 other 1 1 1 2.13260271411454 -0.670344121805188 0.0783726651531942 4.08004682622267 5.15738895006022 0.791107063231099 0.430147473915465 -19.2319805757891 11.6784453533531 -1.64679287301431 0.101722359962169 ZNF32-AS2 other 1 1 1 0.791107063231099 -1.64679287301431 4.75570793225659e-12 28.7778675584185 3.75914864538133 7.65542155237102 2.02642914107965e-12 24.4363861654045 8.82813019098244 2.76801379643962 0.00633682610226492 KLHL7-AS1 other 5.90849153503559e-08 1 2.73851634125504e-08 7.65542155237102 2.76801379643962 0.651829837679995 2.12020985656081 2.28963676178783 0.926002714467807 0.355884101305556 1.73661885360271 7.82370694197398 0.221968801551832 0.824630358571929 SETSIP other 1 1 1 0.926002714467807 0.221968801551832 0.982354824149067 1.22510356621602 13.9751355364435 0.0876630901375712 0.930255462718281 -5.98283233329899 43.8915534425527 -0.136309423204389 0.891750198402588 FOXD3-AS1 other 1 1 1 0.0876630901375712 -0.136309423204389 0.880777572362177 -1.11001034929844 4.1250035050075 -0.269093189363587 0.788218155257127 -5.7085191269655 11.400795355395 -0.500712358130711 0.617288439577939 STMND1 other 1 1 1 -0.269093189363587 -0.500712358130711 0.121238719624838 -167.298624145816 98.6573540773851 -1.69575421630089 0.0920070229991277 -574.132440746336 337.397364435539 -1.70165063887458 0.090892673830685 MIR205 other 1 1 1 -1.69575421630089 -1.70165063887458 6.08959470023759e-07 621.516230114093 158.11633530423 3.93075281512337 0.000127302891004443 -161.588776240632 292.820856824953 -0.551834927309257 0.581856195219892 HSBP1 other 0.00565845139546077 1 1 3.93075281512337 -0.551834927309257 1.49901039409838e-07 12.1146397998376 2.33690406095733 5.18405526450015 6.72715582432046e-07 2.95923282260696 4.75832360311808 0.621906593462414 0.534922909165701 LINC00271 other 0.00147052919661051 1 0.00742812546121465 5.18405526450015 0.621906593462414 0.0146057065811269 8.28650530264771 10.8215431735918 0.765741555499177 0.44499458310019 -33.2361121131231 16.4996817295601 -2.01434868004628 0.0457024548318328 LINC01508 other 1 1 1 0.765741555499177 -2.01434868004628 2.25954764037867e-06 35.1708151944543 10.1124399067967 3.47797519872683 0.000656957806031172 -21.2432968729233 17.6511628924927 -1.20350693052402 0.230626982400727 KLF3-AS1 other 0.0199495461169033 1 1 3.47797519872683 -1.20350693052402 0.00411674082040973 3.34685990338165 1.47768869537616 2.26492894873888 0.0248762998110016 -3.04106280193237 2.87120696042361 -1.05915834137003 0.29114418819119 LINC00852 other 1 1 1 2.26492894873888 -1.05915834137003 0.0217271765022559 -1604.18283181551 659.019152388926 -2.43419758894774 0.0160390142477166 -4656.32978981267 1993.74500106519 -2.33546907318888 0.0207759947729821 HLA-DPA1 other 1 1 1 -2.43419758894774 -2.33546907318888 0.33525014638274 4.84533375045277 8.32980866834897 0.581686079881251 0.561657153518041 -24.9245644943524 23.4214059475394 -1.06417883495892 0.288969247559482 LINC00689 other 1 1 1 0.581686079881251 -1.06417883495892 0.0201779573765374 9.15477261941774 4.14891298080779 2.20654727196407 0.0301770540683422 -4.14172216858404 10.3425260685254 -0.400455569668632 0.689875260605168 WASIR2 other 1 1 1 2.20654727196407 -0.400455569668632 0.000458656924037263 7713.41616723289 2643.11813359108 2.91830170933489 0.00404004762523793 -9555.28515180887 7918.80196654297 -1.20665792529982 0.229390538561676 RPS18 essential 1 1 1 2.91830170933489 -1.20665792529982 0.00237996657608176 31.4136871668482 9.7157840798204 3.23326320436599 0.00149005466051242 4.52154754399037 15.2528222808221 0.296440059468566 0.767283338732428 FAM225A other 1 1 1 3.23326320436599 0.296440059468566 0.0042392627422841 29.3412413990825 10.0329238173905 2.92449558405139 0.00401322853807147 -26.4085292431194 33.9807395625905 -0.777161697569191 0.438347111804696 FAHD2CP other 1 1 1 2.92449558405139 -0.777161697569191 0.0598923896812 30.8180978090066 12.9652671162964 2.37697361208011 0.018683556936902 14.5831160100486 48.7932203897536 0.298875866228148 0.765437693103864 LINC-PINT other 1 1 1 2.37697361208011 0.298875866228148 5.08953236066372e-12 11.7307704653178 1.48319167748339 7.90913989297867 8.55574305684648e-13 5.50646780009208 6.00485840368499 0.917002105613837 0.360788992571549 DBIL5P other 6.3171275660558e-08 1 1.16332438343942e-08 7.90913989297867 0.917002105613837 4.48251991726024e-05 32.2201748405984 9.14351632182714 3.52382756332849 0.000561196363720251 -8.61059202523692 19.5607487044859 -0.440197466636961 0.660415336718324 PIK3CD-AS2 other 0.343181724865444 1 1 3.52382756332849 -0.440197466636961 0.119447149734043 10.3428406429465 5.77922620767896 1.7896583852703 0.0754739353781243 0.534783492144969 8.92685433543658 0.0599072721531996 0.952307158988886 PCAT7 other 1 1 1 1.7896583852703 0.0599072721531996 0.691658597296299 -4.1913021618904 4.91308911230685 -0.853088976422504 0.395155294419543 -6.89834087481144 15.3579649525302 -0.449170244634199 0.654045450734583 CYP21A2 other 1 1 1 -0.853088976422504 -0.449170244634199 2.90060785358305e-05 21.1632837339153 4.90366799491658 4.31580681152442 2.85314553109429e-05 -16.7006423800551 18.8558444440268 -0.885701111378524 0.377177658761035 IPO9-AS1 other 0.227958771213092 1 0.276954836703322 4.31580681152442 -0.885701111378524 2.31929884151033e-21 36.8658122213388 3.53276962828553 10.4353852926521 1.14165328950769e-19 -13.8602503357587 16.3414233991129 -0.84816664970024 0.397644683528809 PRH1 other 3.30128997100581e-17 1 1.63313503064075e-15 10.4353852926521 -0.84816664970024 4.54726569121516e-25 52.2940179394591 4.8876370957119 10.699243195723 2.70011451799894e-20 12.1361817506659 10.3325836395677 1.17455441678608 0.241997875847335 TRAF3IP2-AS1 other 6.55124568133369e-21 1 3.86845406993708e-16 10.699243195723 1.17455441678608 0.00265021124768693 10.1312237169877 7.32035476231887 1.38397988156771 0.168367099276147 -48.2768004311346 18.6115386798748 -2.59391774433662 0.0104044717563841 DARS-AS1 other 1 1 1 1.38397988156771 -2.59391774433662 0.000477054832397367 317.592920929947 379.777297095862 0.836260943870432 0.404287232163069 -3556.43207470258 1125.43865878462 -3.16004079559808 0.00189511011048606 TAPBP other 1 1 1 0.836260943870432 -3.16004079559808 0.582877410463296 -3.95510167446226 5.53295056894801 -0.714826858685319 0.475805321486109 -8.7125041138515 8.7417992549338 -0.996648843078184 0.320508615723107 PPP1R2P3 other 1 1 1 -0.714826858685319 -0.996648843078184 9.91185776850026e-07 105.152454780362 19.2553992164129 5.46093350745654 1.81738115059824e-07 91.298288113695 28.9457112952904 3.15412142345763 0.00192943698699698 LEF1-AS1 other 0.00904457021375649 1 0.00208090141743498 5.46093350745654 3.15412142345763 2.43811857008784e-06 25.8715207210391 6.25064257144269 4.13901777702637 5.74191957771679e-05 -21.7638678366786 17.7979895290101 -1.22282731997366 0.223275157868191 ZBED9 other 0.021428624112502 1 0.538993990760275 4.13901777702637 -1.22282731997366 3.52977630063016e-09 18.0450646761556 2.8682092403485 6.29140455386129 3.50847334452925e-09 0.96109849011695 8.47386248203547 0.113419174804226 0.909855121265624 TMEM253 other 3.8682818478606e-05 1 4.34664762653729e-05 6.29140455386129 0.113419174804226 0.18252649403105 -15.8804398909671 26.8520534115678 -0.591405046294369 0.555202771193087 -94.6647442697353 51.3955040764258 -1.84188765089195 0.0676075863828392 LINC01697 other 1 1 1 -0.591405046294369 -1.84188765089195 0.0014847825144629 -65.0859076311375 148.125518860312 -0.439396993387181 0.661086993702527 -1146.31904725494 325.891378427856 -3.51748810534643 0.00059660861977185 TMA7 other 1 1 1 -0.439396993387181 -3.51748810534643 0.901095022418906 8.13727313793759 22.5879779726735 0.360247966762759 0.719145888295579 -0.705896420694402 40.6493334197577 -0.0173655103616361 0.986167072535666 LINC00865 other 1 1 1 0.360247966762759 -0.0173655103616361 0.000543300819670647 9.76853959993496 2.88936972172847 3.38085483712042 0.000911917276311162 -8.66622214994306 8.72306545496897 -0.993483563167175 0.322003065766899 GNG12-AS1 other 1 1 1 3.38085483712042 -0.993483563167175 0.05793164052382 5.00113798008536 3.46712323544553 1.44244598200522 0.151527436366486 -8.40453769559032 7.34556605672756 -1.14416474246976 0.254610349643615 SEMA3B-AS1 other 1 1 1 1.44244598200522 -1.14416474246976 0.00368785070017629 149.734719462203 48.4886036264107 3.0880394208887 0.00239052164573367 -16.504684146577 153.65622150781 -0.107413054835128 0.914601107060345 SMIM26 other 1 1 1 3.0880394208887 -0.107413054835128 0.242055380599699 1.68992135158762 20.435500728808 0.082695372822714 0.934227107162177 -45.653364404311 31.7294807814084 -1.4388311210898 0.152717761599273 C9orf172 other 1 1 1 0.082695372822714 -1.4388311210898 0.0864658253910558 17.9882147695848 9.48960693979651 1.89557005719043 0.0605053841297503 -7.11388058870471 32.5673475084047 -0.218435983675638 0.827473261058707 MHENCR other 1 1 1 1.89557005719043 -0.218435983675638 0.0528579541434014 -118.851492034978 67.6651439293594 -1.75646551729876 0.0809463119247221 -461.213098630164 199.31386199825 -2.31400412397917 0.0219557403128584 HLA-DQB2 other 1 1 1 -1.75646551729876 -2.31400412397917 0.00529092417472363 8.35175671085745 2.53712277795683 3.29182205268883 0.00123777436142999 12.0927926313621 9.29960258380503 1.30035585095016 0.195447230958726 LINC01431 other 1 1 1 3.29182205268883 1.30035585095016 0.000879278224987343 9.68342894642139 3.62818963688975 2.66894234192303 0.00844674671121519 -19.3146129257605 13.3236934559946 -1.44964404874314 0.149245378922399 IDI2-AS1 other 1 1 1 2.66894234192303 -1.44964404874314 1.64721120167788e-23 839.358182857714 74.8268815826924 11.2173348013992 1.37770171854392e-21 -67.5109812200757 304.987342263746 -0.221356665883182 0.825115780880336 LINC00665 other 2.36193614208591e-19 1 1.97989513971947e-17 11.2173348013992 -0.221356665883182 0.186320085531642 9.74757366103826 5.29085855440964 1.84234251602024 0.0675558690511842 8.06539261696258 7.55173277459113 1.06801880544552 0.287363371462198 BMS1P22 other 1 1 1 1.84234251602024 1.06801880544552 0.00800090176432337 -6.41657435248194 2.10280069430387 -3.05144199821854 0.00281367269482015 -15.7519385978794 7.34799152060319 -2.14370669232704 0.0341086436863513 SLCO4A1-AS1 other 1 1 1 -3.05144199821854 -2.14370669232704 0.194708652176835 17.4897958322609 20.6329544520664 0.847663182356774 0.397907815324333 -77.1104168160972 67.7024519686528 -1.13896047445668 0.256443537599479 TNF other 1 1 1 0.847663182356774 -1.13896047445668 0.00146284063007435 60.5647832798955 16.8270142699123 3.59925904313214 0.000429681614299625 72.8496330602068 33.6866955654424 2.16256393918731 0.0321181167792865 COL4A2-AS1 other 1 1 1 3.59925904313214 2.16256393918731 0.0180271567404053 20.5485799022501 8.15880209353319 2.51857805431232 0.0128107465166929 4.93184363036609 19.2249679801533 0.256533255891892 0.79788372917639 RPS2P32 other 1 1 1 2.51857805431232 0.256533255891892 5.86949711255895e-06 4.96288269829386 0.961001825591006 5.16428019815856 1.00188236035815e-06 3.44622325544741 3.85066848103881 0.894967528993227 0.372641922800588 LMLN-AS1 other 0.0495502946242226 1 0.0109475685516335 5.16428019815856 0.894967528993227 1.6243601769622e-10 53.6033619672075 9.90304746789618 5.41281480685411 2.33291428990841e-07 -73.468219846118 30.773734995006 -2.38736766460231 0.0181822793583665 PET117 essential 1.90553692359435e-06 1 0.00265299013048385 5.41281480685411 -2.38736766460231 4.70097867284109e-23 61.1759163336787 6.00575070233555 10.1862230661503 2.28581737928232e-18 -239.663657441666 38.4041181158377 -6.24057182406253 5.42084133230957e-09 LYRM9 other 6.73415194884486e-19 7.92689628023629e-05 3.25386103940838e-14 10.1862230661503 -6.24057182406253 0.59374426535312 0.252080452652227 2.82757581130735 0.0891507317484354 0.929075742965718 -3.73389716922707 4.93170047949274 -0.757121642880294 0.450111749733263 SEC1P other 1 1 1 0.0891507317484354 -0.757121642880294 0.479902746945481 1.30467238042576 1.37434144141565 0.949307312658694 0.344545346972018 5.87130218413047 7.00655734044534 0.837972473334143 0.403863272446956 RPL23AP87 other 1 1 1 0.949307312658694 0.837972473334143 7.05993220244197e-14 129.633821151083 20.5528610580949 6.30733700698208 2.79185136932042e-09 -146.927474902728 61.2672894912324 -2.39813897632527 0.0176598682620889 HCG25 other 9.24921717841922e-10 1 3.47027125206528e-05 6.30733700698208 -2.39813897632527 0.000130141347986212 100.013043979406 30.4502702071542 3.28447147756044 0.00127358381320335 -69.613329576599 72.8522553962685 -0.955541172993865 0.340851827261696 SNHG15 other 0.93975067380844 1 1 3.28447147756044 -0.955541172993865 0.501664905248966 8.33352678924748 13.3179405317917 0.625736897484581 0.532413779753848 56.7661381802834 52.6401825809923 1.07838034362709 0.282550255557126 CYP1B1-AS1 other 1 1 1 0.625736897484581 1.07838034362709 2.1239433970611e-08 11.7848939929329 3.86931502239624 3.04573133092549 0.00273134973727214 -18.1863957597173 6.07396099989516 -2.99415747977822 0.00320729154666385 MIR3936HG other 0.000221909606124944 1 1 3.04573133092549 -2.99415747977822 0.000511182345237786 417.584548736461 111.596238051862 3.74192316897275 0.000276225688734685 95.7469417225378 172.953902132422 0.553598042842823 0.580835012827309 SNHG7 other 1 1 1 3.74192316897275 0.553598042842823 0.470243449263482 1.60566204557143 1.31232182776594 1.22352765274418 0.223011456560087 3.13246112327863 6.32849052684629 0.494977611168147 0.62132599781379 LINC01271 other 1 1 1 1.22352765274418 0.494977611168147 0.000653144735418221 -25.7121287276047 46.3850073340517 -0.554319815936068 0.580164073410813 -739.163349933535 189.667601071351 -3.89715136248004 0.000144838732760438 HOXB-AS3 other 1 1 1 -0.554319815936068 -3.89715136248004 0.0677590047486128 5.08893638007563 2.17379180569687 2.34104129325495 0.0205463123003117 4.39747383418271 4.22974927684313 1.03965354595787 0.300173795335214 CTAGE7P other 1 1 1 2.34104129325495 1.03965354595787 0.025886126481687 9.8732501562967 5.95676439916054 1.65748542240282 0.100011922015014 -10.3911495283917 9.3195500704649 -1.11498403354501 0.267066900654673 RNF224 other 1 1 1 1.65748542240282 -1.11498403354501 0.159176638659997 -559.234437897441 769.431173655115 -0.726815415134335 0.468666178484709 -3209.06455866052 1664.0348693343 -1.92848396256523 0.056009061352634 GPX1 other 1 1 1 -0.726815415134335 -1.92848396256523 0.596447412987682 -6.31172291296626 8.69579795703184 -0.725835966308566 0.469093359674246 14.2779751332149 25.4720385417263 0.560535235914701 0.575967733825168 USP32P2 other 1 1 1 -0.725835966308566 0.560535235914701 2.21725385617984e-06 618.430166064321 124.661080183142 4.96089208561144 1.90325157026784e-06 -512.031873702946 495.986164052913 -1.03235112350497 0.303591686230361 GTF2IP4 other 0.0195894378193489 1 0.0204485348709577 4.96089208561144 -1.03235112350497 0.198609954214637 57.5650397763922 32.02499373952 1.79750354503129 0.0743366925693621 58.6280660363653 67.7632067119318 0.865190254138933 0.388363540810789 HOTAIRM1 other 1 1 1 1.79750354503129 0.865190254138933 0.0109093315570869 89.1458472094702 113.45258295808 0.785754232165955 0.433250921258663 -452.345130391678 224.410538954423 -2.01570359618247 0.0456166232920569 TMEM238 other 1 1 1 0.785754232165955 -2.01570359618247 7.91226018862598e-10 29.6997856105489 4.79283094943726 6.19671044605403 5.36400979684899e-09 -6.6766674633979 19.1966155191535 -0.347804406289027 0.728477931859688 ZNF529-AS1 other 8.97883286205276e-06 1 6.60148685698206e-05 6.19671044605403 -0.347804406289027 0.00113191350029665 4.35775798323152 3.02172701552563 1.44214151736453 0.151347146946498 -18.0384628510973 7.42807689795876 -2.4284162777117 0.0163480471315733 B4GALT1-AS1 other 1 1 1 1.44214151736453 -2.4284162777117 0.272998075229458 39.8958625212388 28.2193539216736 1.41377660991017 0.159556224585536 -3.41909857811432 62.8513738787723 -0.0543997428713185 0.95669105218694 TWIST2 other 1 1 1 1.41377660991017 -0.0543997428713185 0.0297599309256527 3.18626144006228 4.41913005078544 0.721015540037335 0.472037344338371 -36.3078294213689 16.6516428069159 -2.18043527851134 0.0308050953260744 LINC01137 other 1 1 1 0.721015540037335 -2.18043527851134 0.000340799606959522 12.1126890172197 3.6257614127638 3.34072974977872 0.00104704134678404 -12.9269155274996 11.3555401306892 -1.13837962604382 0.256718457489651 MYCNOS other 1 1 1 3.34072974977872 -1.13837962604382 0.0410529935445557 -19.0272402016585 63.5260123827709 -0.299518881918975 0.764950667433704 -246.247639182522 108.24531866795 -2.27490336037445 0.0243009228128422 LINC00284 other 1 1 1 -0.299518881918975 -2.27490336037445 0.00697749574033317 18.3645468649176 7.11124143287953 2.58246707529957 0.0107598062014617 -11.9802572868185 20.4207242123337 -0.586671518710519 0.558300395540848 HIST1H2BN other 1 1 1 2.58246707529957 -0.586671518710519 0.00745375506300595 -204.509094630204 114.737651513792 -1.78240614072199 0.0766280455886953 -502.076108368084 157.948948762908 -3.1787239630302 0.00178411478691754 LINC01503 other 1 1 1 -1.78240614072199 -3.1787239630302 0.728500230540087 9.7938494069753 13.2828691723226 0.73732935858336 0.46215602957634 2.6193805930576 23.8725353246896 0.109723603187994 0.912785704100473 LINC01694 other 1 1 1 0.73732935858336 0.109723603187994 0.00427086944855906 58.5580214285083 243.068399183242 0.2409117006788 0.809943992059838 -2239.71445889452 805.590782470485 -2.78021361171245 0.00611019229095731 RPS28 essential 1 1 1 0.2409117006788 -2.78021361171245 0.113005243026965 12.0682897640151 6.13906690361123 1.96581825112804 0.0511416679873987 5.37512622012788 10.612757695845 0.506477804749308 0.613255132589894 KRTAP5-AS1 other 1 1 1 1.96581825112804 0.506477804749308 0.106978427000243 -152.489129966852 100.02907015865 -1.52444814017563 0.129447782724893 72.0415859485985 232.186124674723 0.310275155543958 0.756771226988157 UQCRHL other 1 1 1 -1.52444814017563 0.310275155543958 0.398089834276105 4.00562952120922 3.21934505482326 1.24423740015316 0.215365931713137 -3.18270611084527 12.2412747088814 -0.259997932121899 0.795224296068006 TPRG1-AS1 other 1 1 1 1.24423740015316 -0.259997932121899 0.239630041844267 0.0593544337505203 2.05905999516474 0.0288259855904642 0.977041188929432 -5.44644215772055 3.67649421047793 -1.48142274838848 0.140564006184473 RPL13AP6 other 1 1 1 0.0288259855904642 -1.48142274838848 9.18534956483383e-05 106.472394671559 50.3295359615295 2.1155051926754 0.0359958612007451 -403.999211991077 149.785492233956 -2.69718519441159 0.00777207630073714 TRIM26 other 0.676776555936957 1 1 2.1155051926754 -2.69718519441159 4.96885753778496e-07 60.2714859510576 13.1840639399308 4.57154078026825 9.96515690916407e-06 -55.4542491363913 38.5523415638012 -1.43841455244991 0.152372285570054 RNASEH1-AS1 other 0.00465184442687428 1 0.10120613356947 4.57154078026825 -1.43841455244991 9.38041341151479e-07 38.9298105682952 8.9447209708831 4.35226662687631 2.44428329779767e-05 -14.54235475392 14.6190640884064 -0.994752787591427 0.321416954868672 ZNF879 other 0.00857745002348912 1 0.238733149695898 4.35226662687631 -0.994752787591427 7.59479062287073e-25 31.4419575990033 2.45349798726586 12.8151552445502 8.18456875171267e-26 9.54340012878475 22.7889207850152 0.41877367598118 0.675984580489566 TATDN1 other 1.09334605806847e-20 1 1.18348864149765e-21 12.8151552445502 0.41877367598118 6.98223982420404e-11 54.9074757729579 7.74411378547276 7.09022068812563 5.54745623357995e-11 17.4838062590057 14.2956985936794 1.22301167336697 0.223323027103595 RNF219-AS1 other 8.32282987045121e-07 1 7.27715308721017e-07 7.09022068812563 1.22301167336697 0.520250587404423 1.99818320902653 6.09156550569041 0.328024578765497 0.743350500053408 -10.0189519984701 11.8248283068618 -0.84728097004641 0.398188375297836 LINC01426 other 1 1 1 0.328024578765497 -0.84728097004641 0.00225185141384174 9.84283360411122 3.04232732841128 3.23529736994185 0.00151641681330517 14.1002454284628 4.68822572890887 3.00758671697841 0.00312283200769844 CCDC188 other 1 1 1 3.23529736994185 3.00758671697841 0.0199998086493536 67.8896202669795 27.152478952034 2.50031020692104 0.0137355488547107 -19.3615546748701 62.303810961925 -0.310760359213055 0.75651311586866 ZNF37BP other 1 1 1 2.50031020692104 -0.310760359213055 0.573890869748818 -15.2664155535077 22.2982532025015 -0.68464625524097 0.494602987519614 -71.2553212429205 72.4516637687329 -0.983487714931832 0.32692012607082 MAGI2-AS3 other 1 1 1 -0.68464625524097 -0.983487714931832 0.000279422309139645 28.2829085934482 20.2328823669384 1.39786848361576 0.164162790689885 -159.368341922944 57.5356982294072 -2.76990367419385 0.00629731844874819 PINLYP other 1 1 1 1.39786848361576 -2.76990367419385 2.98668759442202e-07 16.0473890427616 3.11589745909912 5.15016596451197 7.90157976925411e-07 -29.3799567655205 12.8616573799679 -2.28430566120351 0.0237287441250301 SP2-AS1 other 0.00284780662128139 1 0.00868462632438719 5.15016596451197 -2.28430566120351 0.809840205672558 5.14654907189006 12.7265128553897 0.40439585693032 0.686486395109063 31.5559429802072 50.9513597472904 0.619334658323526 0.536617062358053 RPL13AP20 other 1 1 1 0.40439585693032 0.619334658323526 0.315150197337922 5.95890279576081 6.44460274264316 0.924634618101667 0.356612024573189 -9.66398120174556 11.798966239369 -0.81905321243316 0.414030010373114 LINC01506 other 1 1 1 0.924634618101667 -0.81905321243316 0.70576421531799 -1.46460699345573 2.39608089128251 -0.611251063678317 0.541940477939084 1.30473483524122 3.99818132963043 0.32633208143209 0.744619065743657 C5orf58 other 1 1 1 -0.611251063678317 0.32633208143209 0.000259604201524156 27.145077010392 7.53942314671447 3.60041829224312 0.000430326927341765 -19.2817190833122 23.6362517428251 -0.815768899955351 0.415917272735552 FAM133B other 1 1 1 3.60041829224312 -0.815768899955351 0.287875561018881 -0.984144783976585 2.78525951653297 -0.353340425958449 0.724319616679397 -8.6479110640404 5.93328584360913 -1.45752476654319 0.147021040686611 LINC01759 other 1 1 1 -0.353340425958449 -1.45752476654319 0.060211027418482 -5.38048741123311 9.92983234781127 -0.5418507808361 0.588730676835442 -31.327550032279 14.8174454084379 -2.11423421303374 0.0361602765553641 MCIDAS other 1 1 1 -0.5418507808361 -2.11423421303374 9.32998692681558e-10 42.5936287912507 19.6886347395877 2.16336121598153 0.0320556616547502 -173.898730421144 38.6546893866206 -4.49877448714761 1.33896157604578e-05 MAPKAPK5-AS1 other 1.05466172220723e-05 0.194243155836961 1 2.16336121598153 -4.49877448714761 1.43486897780051e-06 137.843952708412 25.4141444114313 5.42390687944662 2.77590321843239e-07 105.155059341974 109.797217173337 0.957720623975062 0.339995129497443 JRK other 0.0129066464553156 1 0.00314093449165625 5.42390687944662 0.957720623975062 1.43542369873183e-09 26.6820561900845 4.48816167527107 5.94498552427326 1.78437674378388e-08 -14.1817398044737 15.7270411704276 -0.901742397110297 0.36860186972183 SDCBP2-AS1 other 1.60666974599054e-05 1 0.000214767584881828 5.94498552427326 -0.901742397110297 0.212580945598076 -3423.87492998784 2335.54312952257 -1.46598659930881 0.144639273856336 -11038.5255434863 7226.81441863548 -1.527440017696 0.128651049750418 HLA-B other 1 1 1 -1.46598659930881 -1.527440017696 1.3929664502383e-14 5.50216701806715 0.677527660832088 8.12094817104561 1.47441693796277e-13 -7.38557564676398 4.41569877154775 -1.67257234446164 0.0964685903652341 FOXP4-AS1 other 1.85320256539704e-10 1 2.02275259719113e-09 8.12094817104561 -1.67257234446164 0.692724665001689 0.163368709346118 3.20411964740999 0.050987081421312 0.959403199665483 -5.25682985279014 7.17762578089536 -0.7323911852276 0.465065125962613 LINC01239 other 1 1 1 0.050987081421312 -0.7323911852276 0.0476023335283631 -11.8794041083533 10.6514290496595 -1.11528735280202 0.266431531056719 77.7874953284879 44.8388367324302 1.73482411670656 0.0847344529491099 APOC2 other 1 1 1 -1.11528735280202 1.73482411670656 2.60997950203107e-10 147.608006871213 20.6974692064548 7.13169351280778 5.20003536253889e-11 14.5354330977033 76.4248374850406 0.190192528712259 0.849439792507185 GTF3C2-AS1 other 3.03305717931031e-06 1 6.82868643808608e-07 7.13169351280778 0.190192528712259 5.45144600901277e-08 46.5945592132573 12.7791035965495 3.64615239724939 0.000378924929883301 -81.3766004661707 27.7097333075325 -2.93675148594987 0.00390070018656145 SEMA3F-AS1 other 0.000553158226534526 1 1 3.64615239724939 -2.93675148594987 0.302569399674783 -7.85128923280658 9.77155782457283 -0.803483883916923 0.422933541438043 -26.8851991546847 17.3791234047828 -1.54698246444846 0.123920026122253 C19orf81 other 1 1 1 -0.803483883916923 -1.54698246444846 0.000456154660697073 110.691546959311 123.714503317273 0.894733794270154 0.372608786439127 -788.014847965583 276.468752983887 -2.850285391968 0.00509283969396307 ANKRD65 other 1 1 1 0.894733794270154 -2.850285391968 0.0241244222511483 14.2706105858443 21.2292523786022 0.672214467629025 0.502461030901048 -128.865834924994 60.4478671151832 -2.1318508174894 0.0346159620129741 ZSCAN31 other 1 1 1 0.672214467629025 -2.1318508174894 0.0487329030670395 -3.80220621249833 141.619868988022 -0.0268479715428906 0.978615526506307 -592.889964896526 287.154765725161 -2.06470529367424 0.0406169640602424 C12orf75 other 1 1 1 -0.0268479715428906 -2.06470529367424 0.827657518282731 9.87252060509901 16.8052648347839 0.587465934167526 0.557810866730942 6.4993199014621 37.6458350513436 0.172643796919312 0.863173840918562 SMIM1 other 1 1 1 0.587465934167526 0.172643796919312 4.0983834496233e-06 307.941964285714 58.6005979693907 5.25492870305801 7.41882365794276e-07 265.974702380953 244.629715220311 1.08725426974977 0.279322853478034 HGH1 other 0.0352010154488145 1 0.00816664108266339 5.25492870305801 1.08725426974977 5.76960474668242e-10 78.5683937397036 15.737691433081 4.99237096328823 1.57020811964113e-06 -25.0155560131799 27.7735705757672 -0.900696435301204 0.36912928633716 NUCB1-AS1 other 6.59177342308467e-06 1 0.0169519668596457 4.99237096328823 -0.900696435301204 0.0028844227669096 57.7035162013987 20.566904022773 2.80564912139939 0.00570177667265204 -53.8328794622328 48.4924749828462 -1.11012851955434 0.26875629527472 PPP1R3E other 1 1 1 2.80564912139939 -1.11012851955434 0.000271829466775089 19.5298213276646 6.81221179690682 2.86688404734163 0.00472227570452586 -21.1870139655033 14.9222929241883 -1.41982295034298 0.157667372153427 ITGA9-AS1 other 1 1 1 2.86688404734163 -1.41982295034298 0.00207819201867397 5.35855263157896 4.56908990895703 1.17278336350403 0.24272948720064 -19.6375355618777 8.10556718532857 -2.42272195305746 0.0165884608964313 SSR4P1 other 1 1 1 1.17278336350403 -2.42272195305746 0.757703513150133 -1.43751064370814 2.00180455760631 -0.718107388778786 0.473765147811349 -2.02426182238946 3.47609404791329 -0.58233804796065 0.561179704355227 RPEL1 other 1 1 1 -0.718107388778786 -0.58233804796065 0.519997830404983 1.54647323933984 13.3659173898462 0.115702738108696 0.908043924478951 -31.7342717412468 33.1319913795652 -0.957813594048545 0.339708321628883 SPAAR other 1 1 1 0.115702738108696 -0.957813594048545 1.32894825764628e-07 20.3277150524024 5.91295088704962 3.43782917205072 0.000757911858419052 -38.742939597995 14.4979387688399 -2.67230674758155 0.00836075407020792 SMIM27 other 0.00130914692860735 1 1 3.43782917205072 -2.67230674758155 0.0486630228260134 4.26557004298859 9.82958921909222 0.433952014465007 0.66495950958156 77.8254461695148 32.3336507441176 2.40694893333916 0.0173272203184416 MSC-AS1 other 1 1 1 0.433952014465007 2.40694893333916 0.649739549372188 8.01274722762098 25.7983359482322 0.310591630549335 0.756528349827428 -19.9122556305018 38.3613051188181 -0.519071381143754 0.604451311640192 NFAM1 other 1 1 1 0.310591630549335 -0.519071381143754 0.29972781780188 32.0093347188491 22.7456071574039 1.40727545751311 0.16145663236731 -21.4958609658136 92.2970750912561 -0.232898615092192 0.81616410321987 GNAS-AS1 other 1 1 1 1.40727545751311 -0.232898615092192 0.278485007431807 -1.7746483937579 1.4215536628043 -1.24838649443388 0.213784141986383 -8.60475246304155 6.51165910211858 -1.32143779766388 0.188315278755986 POU5F1P3 other 1 1 1 -1.24838649443388 -1.32143779766388 0.000146047390951926 9.78537819260991 2.64004833226666 3.70651479104116 0.000291994134748657 -3.07029508095888 5.55878050818966 -0.552332490271106 0.581516147133689 FAM21EP other 1 1 1 3.70651479104116 -0.552332490271106 0.107869476627486 3.40092032728191 3.56101374951076 0.955042739655008 0.341072494698412 -24.4855203963432 16.104631462769 -1.52040240429899 0.130487333682778 LINC00494 other 1 1 1 0.955042739655008 -1.52040240429899 0.000763518280499465 51.6655568390297 13.9004718491596 3.71682036406221 0.000281282002210723 13.8039427193042 23.2384042716824 0.594014225672337 0.553368557566685 DICER1-AS1 other 1 1 1 3.71682036406221 0.594014225672337 0.000575629537303512 120.397916306726 30.8552044254146 3.90202944847635 0.000143272738724409 74.1594944631522 87.1014451013657 0.851415201858568 0.39588696922661 MFRP other 1 1 1 3.90202944847635 0.851415201858568 0.0143595402333519 14.3002919624456 6.09409616043055 2.34658127899237 0.0202455803569624 -5.59524763649447 11.6494946953017 -0.480299599496884 0.631709446282416 BHLHE40-AS1 other 1 1 1 2.34658127899237 -0.480299599496884 0.0375093373988569 -6.74558371670016 12.9978669921119 -0.518976207464956 0.604512783228642 -96.6268981368885 38.5181054963664 -2.50860983144677 0.0131425039623437 B3GALT4 other 1 1 1 -0.518976207464956 -2.50860983144677 0.00215080569210816 17.6814795794041 9.18012324404343 1.92606124224713 0.0559152153809786 -22.3750330801338 13.5735012840439 -1.64843488882536 0.101275968104443 GSN-AS1 other 1 1 1 1.92606124224713 -1.64843488882536 0.175716777124314 22.3409715633386 12.9818160076453 1.72094347587282 0.0872825576105826 4.35096370191661 23.2092822400963 0.187466534161056 0.851543239386904 TSPEAR-AS1 other 1 1 1 1.72094347587282 0.187466534161056 0.0370860759588901 3.46837613588182 1.33772565951364 2.59274097885124 0.0104898572856672 3.37975241309933 4.97570133975765 0.679251462722227 0.498053969070161 TM4SF19-AS1 other 1 1 1 2.59274097885124 0.679251462722227 0.0178630627879047 149.242755776803 76.5396475800229 1.94987513655284 0.0530434601064599 -207.612006835574 204.8423830969 -1.01352075530855 0.312432744661339 APOA1-AS other 1 1 1 1.94987513655284 -1.01352075530855 8.54451087197847e-14 170.435916673505 20.2779835643123 8.40497360760559 3.26878485236082e-14 65.9596790265289 34.2946081277849 1.92332505391976 0.0563592304550424 TTC28-AS1 other 1.11710935140246e-09 1 4.51746066596265e-10 8.40497360760559 1.92332505391976 2.32272153017635e-15 10.7047801285291 1.30924362352136 8.17630877570165 1.17677124409123e-13 -4.72557395365806 4.98970125935602 -0.947065507137788 0.3451388037338 UBOX5-AS1 other 3.13358361636092e-11 1 1.61688368938135e-09 8.17630877570165 -0.947065507137788 9.45118397376036e-08 38.0674785782291 6.37517710849926 5.97120329841163 1.58336905976628e-08 31.9604226171587 11.5527706209049 2.76647253424438 0.0063653981916276 MORC2-AS1 other 0.000942094018504433 1 0.000191001809679607 5.97120329841163 2.76647253424438 0.192981118867534 2.66521189847249 2.7840733589644 0.957306634859607 0.339912945168113 -9.68102771716245 8.34214090073635 -1.16049678761814 0.247642449360365 LINC01814 other 1 1 1 0.957306634859607 -1.16049678761814 1.48573604393927e-06 51.2210184281745 10.0851857506255 5.07883738532013 1.14950991527384e-06 10.6533809532577 18.4931866575908 0.576070590240048 0.565460532629248 MYCBP2-AS1 other 0.0133433954106186 1 0.0125193124872474 5.07883738532013 0.576070590240048 0.0100253023687154 71.1755686105421 44.623925014194 1.59500914784844 0.112872625619859 -73.4121698825052 84.7918706743807 -0.865792549434649 0.388024422295972 ELFN1-AS1 other 1 1 1 1.59500914784844 -0.865792549434649 6.55258124157274e-12 34.502201442183 4.56065867900398 7.56517947747802 3.13569287074351e-12 -15.6783577105001 20.4699181530996 -0.765921856318022 0.4448801465795 COX10-AS1 other 8.10423247957717e-08 1 4.22252401974321e-08 7.56517947747802 -0.765921856318022 1.55882250426052e-18 152.523159163529 18.4128064009488 8.28353678642219 5.09732699901175e-14 -117.214014638586 54.8566819665481 -2.13673176059142 0.0341791044018015 ZBTB22 other 2.18250738821516e-14 1 7.0292139316372e-10 8.28353678642219 -2.13673176059142 3.21923057624968e-20 124.268425616581 12.6201736684371 9.84680788723016 4.53612628417164e-18 -36.2793490519864 55.0157779275289 -0.659435355068075 0.510594811345282 TMEM147-AS1 other 4.55327972704754e-16 1 6.44810351294999e-14 9.84680788723016 -0.659435355068075 1.29649148366311e-07 10.7438115743139 2.01990714637027 5.31896309868515 3.66821270336379e-07 -5.7834990045 6.5244678431341 -0.886432295100688 0.376784935201152 LINC01376 other 0.00127808130459509 1 0.00411976968714787 5.31896309868515 -0.886432295100688 0.0046074445489606 -65.6944392677985 28.1861046703494 -2.33073849814041 0.0210814817492311 -263.797868658556 86.3516237607539 -3.05492655690453 0.00265920469931921 SLC25A3P1 other 1 1 1 -2.33073849814041 -3.05492655690453 0.2261697469486 30.325678666423 19.6554004426197 1.54286750630969 0.124902093099586 -29.3193336175915 70.6875964405161 -0.414773384497008 0.67888130988493 CLEC2L other 1 1 1 1.54286750630969 -0.414773384497008 7.70356682833107e-12 195.171944386802 47.685672461836 4.09288438876484 6.81544221067533e-05 -196.295773673653 74.309233588917 -2.64160675858363 0.00909154165189252 ZBED5 other 9.50774217952621e-08 1 0.63458582423598 4.09288438876484 -2.64160675858363 6.75611499020444e-06 12.255770624159 2.41698926576498 5.07067648075797 1.11796684874053e-06 12.6958492909637 3.89922429350063 3.2559935862437 0.00138788506067346 GUSBP5 other 0.0566973169977957 1 0.012184720684423 5.07067648075797 3.2559935862437 0.148160327453312 5.79298371523868 9.91055025036401 0.584526950461293 0.55971567121861 67.2408766096303 34.1980787364561 1.96621796001509 0.0510596932620013 TRHDE-AS1 other 1 1 1 0.584526950461293 1.96621796001509 0.195913814652294 4.70412888082791 2.59886324306486 1.81007172785294 0.0722217564137523 0.568249226501636 11.0246995246277 0.0515432847155829 0.95895897689923 LINC00854 other 1 1 1 1.81007172785294 0.0515432847155829 3.12698430477517e-05 20.4754003639814 5.84150248875412 3.50515991449117 0.000604127828275986 -12.9269112365579 15.1263136184115 -0.854597594804825 0.394155192547315 VLDLR-AS1 other 0.244530172633418 1 1 3.50515991449117 -0.854597594804825 7.81334431473729e-05 6.23993571235145 2.15464066066006 2.89604472164741 0.00436458990569616 -5.93516020918105 4.81879942182347 -1.23166782628507 0.220066942804774 LINC01134 other 0.581344885210473 1 1 2.89604472164741 -1.23166782628507 0.119767209706561 3.35241869363214 4.99221056261999 0.671529906757928 0.502909061503802 -18.8214676141022 12.2364534396145 -1.53814728319639 0.126105469879884 KCNMA1-AS1 other 1 1 1 0.671529906757928 -1.53814728319639 0.00289562811207039 18.2080552683523 5.21997195658304 3.48815193257689 0.000650380847422557 16.4276583459778 9.99115731900844 1.64421976568457 0.102374534705632 LINC01695 other 1 1 1 3.48815193257689 1.64421976568457 0.000841263214333421 3.12483514850562 1.85306399415004 1.68630719628164 0.0938154754253221 -6.23050315049528 3.59606623340383 -1.73258854150688 0.085224197990538 RNF217-AS1 other 1 1 1 1.68630719628164 -1.73258854150688 0.0702265425009981 -878.470284872291 2284.67147206809 -0.384506173256104 0.701120350963958 -8518.84381139488 4050.2896223815 -2.10326781678045 0.0370266390225346 RPL13AP5 other 1 1 1 -0.384506173256104 -2.10326781678045 2.43987205327713e-11 299.013312668076 51.376409187408 5.82005082483193 3.5131962701657e-08 36.0312698868883 99.0368404703043 0.363816835389575 0.716513988895291 ZNF853 other 2.95785689018787e-07 1 0.00041768390456 5.82005082483193 0.363816835389575 1.06935293714643e-08 80.6269437106832 12.7026153341418 6.34727113982395 2.7633905468652e-09 5.87532111507524 53.7778320119881 0.109251728737698 0.913157070534764 PITPNA-AS1 other 0.000113789846041751 1 3.4357234669175e-05 6.34727113982395 0.109251728737698 0.000980354538266242 42.8271327337148 19.4608294890338 2.20068382788349 0.0292280388208697 -25.226410466067 29.2296285292028 -0.863042458472018 0.389439010397008 ARHGEF38 other 1 1 1 2.20068382788349 -0.863042458472018 1.96115891237427e-05 5.83592213409036 1.43500341755521 4.06683500728724 7.58347164662211e-05 -8.22738086070428 5.40046243434606 -1.52345858539437 0.129694886506236 MKLN1-AS other 0.157029994113808 1 0.702684482776005 4.06683500728724 -1.52345858539437 0.273438166906708 1.552937241938 5.96178425177942 0.260481959150819 0.794833354946429 17.5656264872718 12.3097940958372 1.42696346913 0.155576169912451 CTAGE9 other 1 1 1 0.260481959150819 1.42696346913 1.55437611468919e-06 24.118925831202 7.17630080085937 3.36091344280241 0.000990068610612799 -20.960837595908 12.0869136264281 -1.73417617133269 0.0849832038249337 INTS6-AS1 other 0.0139443081248767 1 1 3.36091344280241 -1.73417617133269 1.70617441898386e-15 55.8973762560476 9.83479487228137 5.68363417661004 6.60133361015593e-08 -51.5989154128343 21.6910887652602 -2.37880707470404 0.0186188828369799 ELOA-AS1 other 2.30760090167566e-11 1 0.000774600485815697 5.68363417661004 -2.37880707470404 0.0630723835852248 -15.8449336466685 9.71023369517517 -1.63177675677791 0.104810322398156 -42.8565549048684 18.9378346922606 -2.26301240882532 0.0250606048615718 CBR3-AS1 other 1 1 1 -1.63177675677791 -2.26301240882532 2.64187295229457e-11 69.9880546856663 14.3597865689495 4.87389240429263 2.68264321886268e-06 -121.345589708652 37.857590141138 -3.20531732887012 0.00163845875104111 NIFK-AS1 other 3.19957233252395e-07 1 0.0285191800597292 4.87389240429263 -3.20531732887012 0.00632073540559836 10.2699108469539 3.33737922039938 3.0772382066084 0.00247099148289415 3.07496285289747 6.18413984803152 0.497233718586792 0.619728836759161 EDRF1-AS1 other 1 1 1 3.0772382066084 0.497233718586792 0.000462453790148544 9.20008424599832 2.75265059375375 3.34226373186446 0.00105074891278376 0.271440606571173 6.62106204791282 0.0409965356927505 0.967353540597411 GLIS3-AS1 other 1 1 1 3.34226373186446 0.0409965356927505 2.41634376246991e-05 46.6328026752029 10.9212905051237 4.26989856677883 3.39628967087667e-05 13.4578569795359 16.2396116632867 0.828705590907718 0.40854530260891 NDUFA6-AS1 other 0.191712714114363 1 0.326824955028462 4.26989856677883 0.828705590907718 1.10449627623257e-21 236.748716148525 25.4906566669045 9.28766642782901 1.69668221278946e-16 -223.093841457161 61.2615655360008 -3.64166079507156 0.000372390151989293 PRMT5-AS1 other 1.57423854251428e-17 1 2.39113424248419e-12 9.28766642782901 -3.64166079507156 0.47784468580153 -1.0553446503167 4.20512808133407 -0.25096611325615 0.802181492364171 -6.92504116247129 6.50607596285116 -1.06439598953538 0.288848463461734 HAND2-AS1 other 1 1 1 -0.25096611325615 -1.06439598953538 8.47852183286208e-07 234.099261846701 48.7337326918553 4.80363905894335 3.74165335305014e-06 -70.3594081592297 109.49212593663 -0.642597881421638 0.521466046022514 ZNF503-AS2 other 0.00778073948601753 1 0.039399609807618 4.80363905894335 -0.642597881421638 4.87818460065748e-06 104.539965014994 41.9057442511228 2.49464523022265 0.0138147098490373 -102.017343757437 67.2223228767144 -1.51761110583067 0.131450760326221 B3GNT9 other 0.0415035945823939 1 1 2.49464523022265 -1.51761110583067 0.0046824177630699 39.9754010695185 21.3974965587505 1.86822794712265 0.0635937668255047 -24.8489839572197 31.1506324655604 -0.797703994764545 0.426247136367423 NR2F1-AS1 other 1 1 1 1.86822794712265 -0.797703994764545 6.03747624122229e-06 103.455597451567 30.0703880196972 3.44044770502461 0.000744133542882485 -76.0418541151996 49.7738351042911 -1.52774753956309 0.128587399000871 CDKN2AIPNL other 0.0509140371422276 1 1 3.44044770502461 -1.52774753956309 0.691407857959887 -36.1909567242382 65.3296672582484 -0.553974300545191 0.580399933750002 -103.657131767902 125.442095675998 -0.826334502858087 0.409892775662783 ZNF295-AS1 other 1 1 1 -0.553974300545191 -0.826334502858087 1.09851946337769e-09 16.2887631196229 2.41469968956099 6.74566828746489 2.85305067081357e-10 8.10667414273449 10.3977167495431 0.779659067274624 0.436780429130867 LINC00987 other 1.23770187938764e-05 1 3.66246114612338e-06 6.74566828746489 0.779659067274624 0.32213426874876 -66.0547047641105 64.2307642889647 -1.02839668024095 0.305658359841154 -186.262863194666 126.112264934997 -1.47696073249238 0.142086142902674 CKMT1B other 1 1 1 -1.02839668024095 -1.47696073249238 0.000648212336887853 51.2264903008651 24.2809621554857 2.10973889637614 0.0364976756408023 -85.3948842107336 49.3340223880959 -1.73095320586182 0.0854630160055621 SMG1P1 other 1 1 1 2.10973889637614 -1.73095320586182 0.421209609470133 -8.35557038025351 9.77526450134706 -0.854766679623051 0.394342155303154 -28.4156937958639 21.7676850059613 -1.30540724877643 0.194190767839636 RNF223 other 1 1 1 -0.854766679623051 -1.30540724877643 0.12966653574813 10.0516044246419 9.43466811601623 1.06539035618841 0.28843431619142 -11.4789098626787 12.8715205306137 -0.891806825415631 0.373944100141615 LINC01502 other 1 1 1 1.06539035618841 -0.891806825415631 2.18774613038079e-08 108.278481533696 19.4094566267914 5.57864568883585 1.07278177746878e-07 -59.1153938174672 84.3308470644744 -0.700993715529397 0.484371691610172 PITRM1-AS1 other 0.000228400696011755 1 0.00124410502733055 5.57864568883585 -0.700993715529397 0.538106557596621 -4.25936070216936 7.72912276184814 -0.55107944761779 0.5823676089038 -27.418611085174 25.2673014964007 -1.0851420397655 0.279532837343577 FOXD2-AS1 other 1 1 1 -0.55107944761779 -1.0851420397655 0.0139064168777874 52.3847218828896 19.1111545278369 2.74105480161269 0.00691186023556681 70.1658359801286 28.6378829021548 2.45010555493434 0.0154975896191948 CECR7 other 1 1 1 2.74105480161269 2.45010555493434 3.46423442896151e-06 41.0593133970349 12.3299969888121 3.33003434098897 0.00108677865954626 -84.767600042793 40.3635602402299 -2.10010215992558 0.0373497540567315 ZNF737 other 0.0299552351072301 1 1 3.33003434098897 -2.10010215992558 3.79022923017116e-05 382.145222672481 115.514950885172 3.30818841841826 0.00116589505673844 -516.641726983431 342.319017982174 -1.50924050328497 0.133260046140588 RGL2 other 0.292795208030722 1 1 3.30818841841826 -1.50924050328497 0.745175370997438 -12.9391410189532 37.1167248778073 -0.348606755082794 0.727854585868678 -66.3848219633301 86.5833720524212 -0.766715598962095 0.444409354862728 UNC5B-AS1 other 1 1 1 -0.348606755082794 -0.766715598962095 0.0474409824534079 115.810488331382 46.646399249614 2.48273157616428 0.0140897019009326 118.835934115895 105.182655130263 1.12980542246936 0.260281386949067 SHISA9 other 1 1 1 2.48273157616428 1.12980542246936 0.181302701295661 -6.1875952909725 10.1673628733564 -0.608574255492256 0.543772155959502 -29.0444517157596 16.1128055140388 -1.80256949607278 0.0735618340517213 DGCR5 other 1 1 1 -0.608574255492256 -1.80256949607278 4.13594855712754e-06 34.9598136459272 8.97414043309401 3.89561695702974 0.000145324820936346 -27.4563029756538 21.7166781709243 -1.26429570671697 0.208021771359397 LINC00857 other 0.0355112543114971 1 1 3.89561695702974 -1.26429570671697 0.000158789149288371 159.248597343716 48.1381084082057 3.30816067788343 0.00117074509755405 -148.588974428158 143.465388859492 -1.03571304277218 0.301970230583905 KIFC1 other 1 1 1 3.30816067788343 -1.03571304277218 0.182706032223717 7.64517797121443 10.5013675505393 0.728017368635172 0.467708438101908 -17.1555632164095 16.4848032735363 -1.0406895934239 0.299650713333227 P4HA2-AS1 other 1 1 1 0.728017368635172 -1.0406895934239 0.646902207250327 -637.456792999032 805.200065109108 -0.791675039063308 0.429800305485779 -1824.54044045995 2490.30326602357 -0.732657931808167 0.464910418373063 AMY1A other 1 1 1 -0.791675039063308 -0.732657931808167 3.15714565213319e-08 171.013471519451 49.3586472134229 3.46471147760599 0.00069463684120564 -196.378148526058 92.9889682049253 -2.11184350484767 0.0363795858867652 FAM200B other 0.000325754288387103 1 1 3.46471147760599 -2.11184350484767 0.00277015096468699 119.474972391727 36.838462819228 3.24321275233467 0.00146081663425024 12.87335559789 71.8500823797438 0.17916967067416 0.858049528446818 LINC00649 other 1 1 1 3.24321275233467 0.17916967067416 0.0614047378758085 12.9492172990816 10.948072677057 1.18278510574909 0.238741103722135 66.6088489931241 27.9656943470692 2.38180565683343 0.018465271540176 PTENP1 other 1 1 1 1.18278510574909 2.38180565683343 0.0292051775249281 49.8269363819062 18.9788442198466 2.6253936122096 0.00952779128322318 60.3584653905723 79.1063483235345 0.763004065662519 0.446628183479735 LRRC37A2 other 1 1 1 2.6253936122096 0.763004065662519 1.34086960014214e-05 22.7420371255982 5.84363346388679 3.89176310700221 0.000150432827344152 -6.82843740778805 12.5269422148173 -0.545100096311701 0.586510757116229 ABCA17P other 0.109321098499589 1 1 3.89176310700221 -0.545100096311701 0.0176694135212296 49.936179067104 34.8035768837015 1.43480019981765 0.153371736881806 -91.9621193259018 70.096637464815 -1.31193339155622 0.191494889088755 GOLGA2P5 other 1 1 1 1.43480019981765 -1.31193339155622 2.55127153959854e-05 29.7029534099951 6.94931843422639 4.27422540658142 3.41992979699349e-05 3.21285381299745 13.072167408338 0.245778202851667 0.806194441572871 LINC01410 other 0.20195865507462 1 0.328997246470773 4.27422540658142 0.245778202851667 0.004652650110158 5.57382639834715 2.2541170273116 2.47273159770007 0.014495560143304 -10.9523340457385 7.29322502472941 -1.50171344070724 0.135218784080467 MAP3K20-AS1 other 1 1 1 2.47273159770007 -1.50171344070724 0.214857227530244 30.4719950299515 31.7612236981382 0.959408721765897 0.338907122869765 -30.2358835230348 54.0307904134954 -0.559604686358294 0.576589362132756 CD81-AS1 other 1 1 1 0.959408721765897 -0.559604686358294 1.3977497585829e-05 10.9157967441069 2.60388411657865 4.19212079163095 4.73618135151354e-05 -3.84134694737803 5.7547923115257 -0.667504010472208 0.505489730219233 PAXBP1-AS1 other 0.113692965363133 1 0.449368886631604 4.19212079163095 -0.667504010472208 5.26297508803233e-06 303.807623624144 79.1270466823275 3.83949150590499 0.000189900080405614 -116.024156628462 115.699351018057 -1.00280732439333 0.3177748232093 TMEM250 other 0.0446405546966902 1 1 3.83949150590499 -1.00280732439333 2.06605900263196e-06 8.30685198343334 1.66246594859071 4.99670503956796 1.54008661923667e-06 1.38889504269995 5.48599804108466 0.253170896580442 0.800467355868679 OR2W3 other 0.0183032167043165 1 0.0166313954011368 4.99670503956796 0.253170896580442 0.447327813924456 -7.80696958673643 10.31125670675 -0.757130756101318 0.450128383176647 -47.8488680119607 38.6164331112888 -1.2390804679983 0.217200839255582 LINC00707 other 1 1 1 -0.757130756101318 -1.2390804679983 0.103595725234696 5.79883827920814 3.08401560851078 1.88028823952947 0.0619821040454897 12.442108709519 12.5893087145668 0.988307538691348 0.324572676702913 SCARNA7 other 1 1 1 1.88028823952947 0.988307538691348 0.0415220667211685 4.50491902527622 2.063317975811 2.18333726458499 0.0306420059141679 -5.31894743670133 8.93007882249523 -0.595621555243464 0.552369580900004 SCARNA12 other 1 1 1 2.18333726458499 -0.595621555243464 0.347351947305128 4.43146477782082 3.36677519668045 1.31623423571319 0.190144140522055 -3.84723221367573 16.3760183728382 -0.234930868180807 0.814589325939979 SNORD10 other 1 1 1 1.31623423571319 -0.234930868180807 0.493474481948636 3.24777406133698 4.07959658250992 0.796101770273283 0.427222675043582 19.9785325068927 18.1503668968186 1.1007233418733 0.272768675240201 SCARNA10 other 1 1 1 0.796101770273283 1.1007233418733 0.000432135831698452 839.714107025937 236.671492565299 3.5480154281541 0.000513884880506676 -99.2945876875342 649.102964795233 -0.152972013798855 0.878619305222227 TXNDC5 other 1 1 1 3.5480154281541 -0.152972013798855 3.47321772389186e-07 218.535751840168 39.7852181550265 5.49288811207782 1.62582815817358e-07 50.8163336838412 73.7298932316183 0.689222938709602 0.491733754251996 CASTOR1 other 0.00329573629820098 1 0.00186726363966235 5.49288811207782 0.689222938709602 0.164430169386298 154.820221487128 81.9875097449888 1.88833911370983 0.060911286779652 7.93089313965199 268.407154168503 0.0295479945913552 0.976466818725143 RBM14 essential 1 1 1 1.88833911370983 0.0295479945913552 0.121397326232364 4.44569854418152 2.16023229876716 2.05797244431475 0.0413007339031345 5.22008685172078 9.61677846295748 0.542810346710995 0.588055432355854 LINC01119 other 1 1 1 2.05797244431475 0.542810346710995 0.26679726677713 0.950841279229032 0.865830507745167 1.09818407958996 0.273872131283056 -5.45393538923004 5.5180719476846 -0.988376998512773 0.324549166948783 LLPH-AS1 other 1 1 1 1.09818407958996 -0.988376998512773 1.28605519425779e-11 71.9063248577524 12.5712621220713 5.7198970285972 5.48876028483799e-08 -141.222350585534 55.2106712369529 -2.55788142802026 0.011509561511572 ALKBH6 other 1.57490319088809e-07 1 0.000646521073951066 5.7198970285972 -2.55788142802026 2.42657301438544e-08 12.1360957756963 2.70708350098141 4.48308881912825 1.42337767324621e-05 -10.0192373301904 6.14753424088684 -1.62979772663211 0.105174801145562 ASB14 other 0.000252363593496085 1 0.14222437099582 4.48308881912825 -1.62979772663211 0.068785872616033 20.9229671897292 60.3663631184501 0.346599763657692 0.729401511843261 -183.155069477466 95.7238606717773 -1.91336901992991 0.057699268022294 PCDHA13 other 1 1 1 0.346599763657692 -1.91336901992991 0.00177391250613266 3.96667920927794 1.56933532810973 2.52761735381043 0.0125055417761037 -8.35179336943813 4.75195098950713 -1.75755040148349 0.0808371842798772 KLHL41 other 1 1 1 2.52761735381043 -1.75755040148349 0.0360289559466403 58.9307425549078 33.6508540212841 1.75124062282741 0.0818825819410704 -150.978853942302 110.69367575844 -1.36393387343803 0.174565752890477 GATS other 1 1 1 1.75124062282741 -1.36393387343803 0.000173539339665517 14.3492970085287 3.35036686134468 4.28290321698369 3.25669392433778e-05 9.61924802386534 14.5455647115612 0.661318292869008 0.509409404980347 MYLK-AS1 other 1 1 0.314336097577083 4.28290321698369 0.661318292869008 0.014095449920964 2.73226284808938 1.70467614682715 1.60280464601727 0.111139064087464 -5.56931999939563 4.09581297648361 -1.35975935214138 0.176002272086075 PSMD6-AS2 other 1 1 1 1.60280464601727 -1.35975935214138 4.51780387946673e-05 811.955356646469 198.66480058771 4.08706199711505 6.95223478076641e-05 -1511.75311335964 785.105563809944 -1.9255412049603 0.0559691109789954 NME1 other 0.345601572764011 1 0.646835924002507 4.08706199711505 -1.9255412049603 0.13070403594434 8.29324055665987 19.2865767175584 0.430000651650625 0.667824861211715 -167.506516456816 93.9361667756139 -1.78319514417636 0.0766181072226744 TNFSF12 other 1 1 1 0.430000651650625 -1.78319514417636 7.75509738585459e-07 55.111025285685 10.5590445542541 5.21931932406531 5.61162947392747e-07 -45.4541199990919 43.4292188945039 -1.04662531715127 0.296881074687998 CDRT4 other 0.0071362406144634 1 0.00622946987900688 5.21931932406531 -1.04662531715127 3.12583848920959e-05 261.002453177589 55.9950624734865 4.66116906827586 6.85774138250692e-06 167.510250202642 112.243582237024 1.49238154078967 0.137685520350733 APOBEC3G other 0.244471828241082 1 0.07061092344014 4.66116906827586 1.49238154078967 1.06111580667718e-05 71.2462813947816 15.4389584858365 4.61470775118295 8.76384915732586e-06 13.2438632853776 35.4607803624662 0.373479183199129 0.709352771799402 TLR9 other 0.0874677759444001 1 0.0894613721979824 4.61470775118295 0.373479183199129 0.133997783664203 10.5192897678646 26.0207049573246 0.404266132878291 0.686592853441382 -105.101320657827 66.5972566041415 -1.57816291566717 0.116634754682042 MRPS17 other 1 1 1 0.404266132878291 -1.57816291566717 1.12949628423436e-08 9.5852563628878 2.03818843509115 4.70283129756801 5.63434484083275e-06 -3.38357841843577 3.49785915367839 -0.967328377095332 0.334886821252754 SUGT1P3 other 0.000120031570125586 1 0.0584675964133215 4.70283129756801 -0.967328377095332 1.69582025861977e-13 395.930332513019 81.8967290871051 4.83450727430041 3.3854717840303e-06 -297.883837921364 153.743859861804 -1.93753323345156 0.054637384671038 GET4 other 2.1996484574557e-09 1 0.0357302692086558 4.83450727430041 -1.93753323345156 1.75085660384238e-14 431.338220424671 67.9331098310997 6.34945494909767 2.36881774960365e-09 -258.812316433146 113.002805685815 -2.29031761523453 0.0233781704365546 ADSL essential 2.32478739858191e-10 1 2.95249444310599e-05 6.34945494909767 -2.29031761523453 0.0422012808448528 7.23388394355765 3.46347799783715 2.08861842000296 0.038355844896289 18.5475673986271 7.87651694964274 2.35479305347885 0.0197699190668524 LILRA2 other 1 1 1 2.08861842000296 2.35479305347885 0.0100613419136361 22.1706656346749 7.550906661558 2.93615940818694 0.00385441115027774 -24.1316434468524 33.1007725734435 -0.729035655989886 0.467131962403458 LINC00888 other 1 1 1 2.93615940818694 -0.729035655989886 0.350146936728617 -26.9669567055343 167.42323778426 -0.161070572176389 0.872257475952454 -718.744807733922 508.458312185635 -1.41357666992277 0.159586136059423 AMY2B other 1 1 1 -0.161070572176389 -1.41357666992277 8.23956578974814e-11 296.290461474601 57.1597915809671 5.18354691785227 6.74278767600852e-07 -621.796984117721 204.767191612666 -3.03660454206894 0.00281052062542134 LY6G5B other 9.78942811479976e-07 1 0.007444711873081 5.18354691785227 -3.03660454206894 0.314194575816838 -109.248584579671 99.8759545144233 -1.09384270829566 0.275699380217438 -427.594015806635 295.803147937817 -1.44553571788398 0.150300614323441 PSMB9 other 1 1 1 -1.09384270829566 -1.44553571788398 0.0119708933586904 11.7666137472131 4.02557605352369 2.92296396609213 0.00399012002306384 -8.57094836627901 16.9002772728295 -0.507148387444416 0.612776154820459 ERICH6-AS1 other 1 1 1 2.92296396609213 -0.507148387444416 0.173973091847102 235.948008678134 219.783015858522 1.07354978161742 0.284832746429984 -258.26041505243 344.919095012429 -0.748756501993964 0.455233789518537 PCDHGC3 other 1 1 1 1.07354978161742 -0.748756501993964 0.0205447051077417 27.3948818960177 10.7377141671334 2.55127687975432 0.0116948871145093 -20.6726327577717 37.2256542126839 -0.555332960427272 0.579462409073261 SMKR1 other 1 1 1 2.55127687975432 -0.555332960427272 0.00262992890501065 85.8367372462511 28.2616663120778 3.03721430641789 0.00280235753419619 10.9357490717969 56.8146085257833 0.192481288801525 0.847617181480853 ZNF542P other 1 1 1 3.03721430641789 0.192481288801525 5.65112278962143e-06 62.9614376466547 42.8415768805649 1.46963399181549 0.14384233715976 -212.797075487896 80.426037347337 -2.64587293501589 0.00905374082851871 COX19 other 0.0477915454318284 1 1 1.46963399181549 -2.64587293501589 0.0902595062273923 17.9014042848692 9.28070389466287 1.92888432688429 0.0556086168190884 43.2786836758313 38.7541068351171 1.11675089971663 0.265863031414676 TCAM1P other 1 1 1 1.92888432688429 1.11675089971663 0.0379501589638199 3.60010735373055 2.09882737988517 1.71529463939408 0.0882516034736157 -3.4154052603328 4.07810373098911 -0.837498378076916 0.403577529321655 GHRLOS other 1 1 1 1.71529463939408 -0.837498378076916 0.00119654248774823 57.3995732541823 15.3899152860905 3.72968740809511 0.000271884704105999 55.2023260245653 62.3004270087823 0.886066575703945 0.377009471686737 ACAD11 other 1 1 1 3.72968740809511 0.886066575703945 0.0698898995044065 -6.34154742978276 24.1746048001255 -0.262322692851212 0.793427851389241 -165.229199788023 72.8270784529638 -2.26878797417005 0.0246888012231049 PPIL3 other 1 1 1 -0.262322692851212 -2.26878797417005 1.11501714370736e-08 18.2878122990495 3.12854113349752 5.84547606014846 3.56389809243992e-08 -11.6634814976608 13.7726271335676 -0.846859599446625 0.398561129076227 RPL13P5 other 0.000118526322376093 1 0.000423533649305561 5.84547606014846 -0.846859599446625 0.00184924399267787 6.45084849480195 4.69790198787213 1.3731339034861 0.171746310028664 -25.4988256283 11.0588573446456 -2.30573782025011 0.0224863663640466 CDKN2B-AS1 other 1 1 1 1.3731339034861 -2.30573782025011 0.0481646888828067 6.44456714870933 3.01371380265468 2.13841378800884 0.0340813452845947 17.3726124080746 12.2800632953008 1.41470055897208 0.159201584272563 TM4SF1-AS1 other 1 1 1 2.13841378800884 1.41470055897208 0.73279645247775 26.1478430601384 510.61265730862 0.0512087639933579 0.959225963113256 -1663.75851049883 2110.25226039093 -0.788416883482271 0.431672779446367 LINC02067 other 1 1 1 0.0512087639933579 -0.788416883482271 0.409282101917315 -78.9319946659594 61.3722001437441 -1.28611968417438 0.200396266976092 -50.3211880765038 152.333998423398 -0.3303345845137 0.741611178037712 AQP1 other 1 1 1 -1.28611968417438 -0.3303345845137 0.573783006569817 8.22692814334693 10.6492708030069 0.77253441062124 0.440989714201545 -29.087187002934 44.5639534324146 -0.652706610670156 0.514924952064363 AADACP1 other 1 1 1 0.77253441062124 -0.652706610670156 1.03490457944992e-11 145.161468796312 19.1985193170558 7.56107626838449 3.52326565285062e-12 -45.851045611724 78.9858145046315 -0.580497218383884 0.56243898253679 ISY1 other 1.27158725677012e-07 1 4.73914462964937e-08 7.56107626838449 -0.580497218383884 4.959540060606e-05 118.919359857931 32.0682031417376 3.70832626113542 0.000290083668971138 42.349928840832 65.0940744048577 0.650595760490169 0.516270696279052 PNMA2 other 0.377718571015753 1 1 3.70832626113542 0.650595760490169 0.0209215746414456 99.2277218701278 55.4977813063222 1.78795835679333 0.0757881305369546 -250.767793143945 171.095956982504 -1.46565586683961 0.144821291144972 LRRD1 other 1 1 1 1.78795835679333 -1.46565586683961 0.461061920267227 -17.50060331989 19.2871374079605 -0.907371734317966 0.365618765261034 -49.0728368354876 42.5586049092039 -1.15306497805042 0.250658780782299 KRBOX1 other 1 1 1 -0.907371734317966 -1.15306497805042 0.166815766380093 167.809622706819 193.637999297123 0.866615144320553 0.387604676604863 -310.766807785499 293.366661973226 -1.05931193986132 0.291243752030868 PCDHGC5 other 1 1 1 0.866615144320553 -1.05931193986132 0.000177794445119257 104.337722046253 28.3365666483992 3.68208764812189 0.000334391300885218 -107.499096628629 96.5305003392064 -1.11362829624708 0.267432276598587 ARHGEF25 other 1 1 1 3.68208764812189 -1.11362829624708 1.19206055297435e-05 175.227567054219 41.1879940901865 4.25433602497212 3.63869087704225e-05 -227.743579486589 199.070036174348 -1.14403746471985 0.25439480365727 TMEM189 other 0.0976829858961627 1 0.348986842017122 4.25433602497212 -1.14403746471985 2.30277127862579e-06 71.8027613802939 16.8604754250628 4.25864393322862 3.58871877674898e-05 -94.2117635989065 54.2116995439394 -1.73784929067842 0.0842626545749955 RDH14 other 0.0203035343636436 1 0.344588776943437 4.25864393322862 -1.73784929067842 6.26074805696859e-05 24.3775098365494 5.55690804721283 4.38688379030789 2.13882301818461e-05 -22.9401767591263 21.9259476839799 -1.0462570234028 0.297103307212218 LINC00886 other 0.470808253884038 1 0.210331855608275 4.38688379030789 -1.0462570234028 3.0918232951324e-05 84.1437405278009 22.7904235352384 3.69206567827485 0.000307664559518086 -155.813606861593 80.1020181092522 -1.9451895287966 0.0535618649646806 NDUFB2-AS1 other 0.241966091077062 1 1 3.69206567827485 -1.9451895287966 1.39423092417247e-08 3031.0147460515 601.768161687384 5.0368479740643 1.33349583092893e-06 -11231.7505567318 3321.10113313285 -3.38193572146257 0.000916641010412369 MIF other 0.000147412035612755 1 0.0144564283031006 5.0368479740643 -3.38193572146257 0.228411998235937 13.1153515373038 8.73398148448163 1.50164636375826 0.135363022218927 2.87799194593432 18.4806466338433 0.155730045758458 0.876462404247124 HOXA11-AS other 1 1 1 1.50164636375826 0.155730045758458 7.18484167546328e-05 14.7843312814773 5.66254991547911 2.61089641630583 0.00991709157524704 -28.436543385732 14.5360604027561 -1.95627581324168 0.0522301159917204 TPM3P9 other 0.53706691524088 1 1 2.61089641630583 -1.95627581324168 2.08030768461409e-09 43.2467352245172 6.87209196081602 6.29309611557962 3.08100209479415e-09 -2.4419498086418 27.6780670006393 -0.0882268912993596 0.92981096969591 NSUN6 other 2.31059774530087e-05 1 3.82290739922058e-05 6.29309611557962 -0.0882268912993596 0.0604667758418114 -12.3481898548236 9.10559425625783 -1.35611026664595 0.17699895493949 -63.5201112425608 26.8213595894883 -2.36826589758169 0.0190811082993676 HLA-DOB other 1 1 1 -1.35611026664595 -2.36826589758169 1.27234954593737e-05 26.9939280649457 5.65153272508735 4.77639064976457 4.30008924570245e-06 17.64209472046 13.5788965637364 1.29922889077561 0.195913316152303 PRICKLE2-AS1 other 0.10400185188492 1 0.0450907358304359 4.77639064976457 1.29922889077561 1.31324929527433e-05 38.0115020761641 17.4569415430657 2.17744339593457 0.0309697262628146 -103.178280910719 39.3503390203714 -2.62204299834123 0.0096178428980618 YAE1D1 essential 0.107213672466196 1 1 2.17744339593457 -2.62204299834123 0.147476563874572 12.8018407914021 8.76234106566162 1.46100690391644 0.146162328801683 -8.75107656509361 21.0532131325418 -0.415664654606434 0.6782656981567 ADAMTS9-AS1 other 1 1 1 1.46100690391644 -0.415664654606434 0.703441753914088 0.574098011114025 3.85976049723289 0.148739283570989 0.881957816227048 6.97057284446231 8.5924218063483 0.81124658467212 0.418500955587104 TDGF1 other 1 1 1 0.148739283570989 0.81124658467212 1.44599971294736e-05 54.1586400931976 11.2618435213421 4.80903859040155 3.63583233481119e-06 -27.0177540248004 45.6829250548094 -0.591419091320992 0.55512399037257 WWTR1-AS1 other 0.117439270144046 1 0.0383071294795707 4.80903859040155 -0.591419091320992 2.73370843388311e-07 3.30839786775941 1.43011436981354 2.31337992092951 0.0220247089631273 -11.4321997846924 3.37694824892907 -3.38536422295421 0.000901990644224551 SUCLG2-AS1 other 0.00261861930881663 1 1 2.31337992092951 -3.38536422295421 3.28060131068482e-14 228.937237334319 26.3012791354126 8.70441457069945 4.7717761893521e-15 179.752062069921 53.1158761849303 3.38414942914787 0.000907056006209618 PDXP other 4.33072179023503e-10 1 6.65567342890831e-11 8.70441457069945 3.38414942914787 0.000421768874728183 124.937159619525 39.0960892603254 3.19564340022907 0.00169491267147504 -115.324179598531 116.896920380509 -0.986545917746516 0.325422855207129 RPP21 essential 1 1 1 3.19564340022907 -0.986545917746516 0.163664598116713 -2.19093595776428 8.28990269448881 -0.264289707431769 0.791907775205196 -29.1847191935422 16.8015019537329 -1.73703037227919 0.08436836355222 HNF1A-AS1 other 1 1 1 -0.264289707431769 -1.73703037227919 0.0688934411928849 36.4949771592366 24.6134284520658 1.48272627806849 0.140151684362466 -103.50231598428 77.5767514856578 -1.33419244815137 0.184072781681136 CD302 other 1 1 1 1.48272627806849 -1.33419244815137 9.64376528851692e-05 47.2428386353822 15.6752875045204 3.01384192294772 0.0030143453227929 -74.153056817948 47.9435884048151 -1.54667306484929 0.123981416005725 EGFL8 other 0.708720311053108 1 1 3.01384192294772 -1.54667306484929 0.130615839397826 285.446504254636 327.227862928671 0.87231723392961 0.384393352500005 -1696.42589814639 1094.77075537221 -1.54957180745079 0.123296946757652 ATP5J2 essential 1 1 1 0.87231723392961 -1.54957180745079 6.09447560028428e-06 40.1878339429987 9.50396677235027 4.22853266489909 4.11599776344976e-05 -8.20256601695938 22.2565263057627 -0.368546551437164 0.712995962993408 PTPRG-AS1 other 0.0513642403591959 1 0.392336906812032 4.22853266489909 -0.368546551437164 1.1433048676277e-06 243.686945992149 53.0616999641891 4.59252052151763 9.00598819907104e-06 24.4607050145624 82.859666606844 0.29520641364181 0.768231261351177 ARHGAP8 other 0.0103812081980595 1 0.0917980377131311 4.59252052151763 0.29520641364181 3.45931585764022e-06 13.1479508492953 2.96629714841766 4.43244563556585 1.81126676658809e-05 -4.94662811709434 8.49253111356768 -0.582468059397698 0.561143796918734 GUSBP2 other 0.0299196228527303 1 0.179351635227553 4.43244563556585 -0.582468059397698 0.0117283438154345 243.337731376905 138.497817350566 1.75697881765868 0.0808959564217016 -430.807608285321 284.816781993609 -1.51257803444668 0.132423133115739 ARPC4 essential 1 1 1 1.75697881765868 -1.51257803444668 4.16633615997173e-05 5.58523027610641 2.77810808259967 2.01044383805252 0.046129801071864 -14.9078754990721 6.37301597274967 -2.33921828578754 0.0206085934642362 CORT other 0.319974617085829 1 1 2.01044383805252 -2.33921828578754 6.40602455265115e-06 8.53145732871614 1.74210178430721 4.89722093483124 2.47486569288104e-06 15.0353409495453 7.3589408773802 2.04313925061698 0.0427773981923218 PAQR9-AS1 other 0.0538554484141382 1 0.0263746436890332 4.89722093483124 2.04313925061698 0.916702028300643 -1.26242449003418 6.33041375930356 -0.19942211331429 0.84220264108239 3.34769603408534 15.7179954944985 0.212984921344269 0.831627909826593 INMT other 1 1 1 -0.19942211331429 0.212984921344269 3.17276500739087e-07 753.931415057156 162.114278448176 4.65061697386618 7.13838180119861e-06 -1047.39353567205 524.809767078109 -1.99575846597414 0.0477468144106509 ARPC1A other 0.00302110684003759 1 0.0733468730073157 4.65061697386618 -1.99575846597414 1.84769671101886e-07 270.080404459751 48.7680893560628 5.53805588912568 1.25961881917555e-07 93.6304927846184 73.1793952456133 1.27946524387589 0.202620882355647 TMEFF1 other 0.00179910228751907 1 0.0014558674312031 5.53805588912568 1.27946524387589 5.64834943164059e-30 16.1084974115326 1.11259357637593 14.4783304106456 2.79720816154157e-30 -1.93242485638353 7.15498083478823 -0.270081066742749 0.78746911069045 RPSAP52 other 8.18445832644721e-26 1 4.05902876321297e-26 14.4783304106456 -0.270081066742749 0.0240141395516716 394.231115440947 283.48169632153 1.39067573164866 0.166411277795572 -871.500178494576 552.905351501805 -1.57621946708854 0.117110378778894 ATP5O other 1 1 1 1.39067573164866 -1.57621946708854 0.0563431616645838 134.239738659926 59.2736093148524 2.26474716508091 0.024914246827572 11.7446550150642 97.760961506186 0.120136451545856 0.904530638038487 PLEKHO2 other 1 1 1 2.26474716508091 0.120136451545856 1.51498946443011e-17 143.168441843355 18.400131201014 7.78083809725581 1.1718568645781e-12 46.4785023562239 34.2275572082275 1.3579263653981 0.176567726035229 C8orf58 other 2.10295687557543e-13 1 1.58915509405436e-08 7.78083809725581 1.3579263653981 0.00114603204784659 16.6638729020919 8.97608513964684 1.85647446997673 0.0652481098551357 -24.5925698728332 15.5924284159548 -1.5772122992509 0.116746759487987 HOGA1 other 1 1 1 1.85647446997673 -1.5772122992509 3.17953407116866e-10 698.667697920026 118.907869265832 5.87570614319964 2.89916452396347e-08 -49.7228850908313 195.339026702011 -0.254546599982211 0.79944417329706 PI4KA essential 3.68126454759907e-06 1 0.000345812344418363 5.87570614319964 -0.254546599982211 0.178183520998359 148.23831264788 90.8398163289383 1.63186495348138 0.104699460401963 -11.1410853242904 144.784187664931 -0.0769495999803087 0.93876099474073 AKAP2 other 1 1 1 1.63186495348138 -0.0769495999803087 2.17110830759099e-07 110.056781107198 81.3808421013916 1.35236719435858 0.178453933069477 -595.951393463455 142.139440662012 -4.1927236429792 4.8800374648472e-05 HYPK essential 0.00209967884427125 0.702383792315457 1 1.35236719435858 -4.1927236429792 0.00098715767681196 316.010502245814 85.6097986151573 3.69128893371634 0.000311044204007217 -34.7724916292365 373.791203935189 -0.0930265112264805 0.926005812420657 SDHAP2 other 1 1 1 3.69128893371634 -0.0930265112264805 8.16953776090842e-06 66.3665037395107 13.5698053329484 4.89074840140621 2.50450146333174e-06 -21.676982922742 55.6025239464703 -0.389856096165902 0.697181609771603 AMACR other 0.0681094363126935 1 0.0266754450859463 4.89074840140621 -0.389856096165902 0.0140102395587567 62.1771459154066 38.597146415304 1.61092598002927 0.10925696120888 -121.971656734016 72.7549765644202 -1.67647166549517 0.0956879625990213 MTFP1 other 1 1 1 1.61092598002927 -1.67647166549517 0.378500510396429 123.930621588308 163.833776242245 0.756441220063583 0.450571114673865 -202.549392498679 377.681655828583 -0.536296612167496 0.592548007797003 SNHG3 other 1 1 1 0.756441220063583 -0.536296612167496 0.576787655576474 -7.16344152788626 14.1445210746474 -0.506446382318733 0.61339462651917 -32.3163465783129 30.8908765767726 -1.04614533996786 0.297420395585902 ARHGDIG other 1 1 1 -0.506446382318733 -1.04614533996786 2.73219927741393e-05 17.0577755726555 5.11073060082555 3.33763935236581 0.00106874928769029 -17.1068237918995 10.3720102142574 -1.64932577567118 0.101201849683912 TCP10L other 0.215570522987959 1 1 3.33763935236581 -1.64932577567118 7.51617605104217e-08 243.751112679947 56.6937654466057 4.29943417516539 3.02642808292446e-05 -72.7060222842932 86.1131841510684 -0.844307674847384 0.399807176914013 ARFGAP3 other 0.0007558266636928 1 0.293170088392892 4.29943417516539 -0.844307674847384 2.57606634010221e-16 432.274496766004 55.7143585748516 7.75876287232578 1.52592889239437e-12 -49.1627843303192 88.8204696589877 -0.553507367379073 0.580786506253424 C22orf39 other 3.52560439306388e-12 1 2.06626031319122e-08 7.75876287232578 -0.553507367379073 5.88488145841418e-09 2371.15086143963 391.172832654808 6.0616450415207 1.03168706295152e-08 -740.238574974449 1256.77859667455 -0.588996802565803 0.556743529275957 PEG10 other 6.36096836839988e-05 1 0.000125463463725534 6.0616450415207 -0.588996802565803 0.00077650755457436 59.4376159072575 19.975070873342 2.97558973803597 0.00339338468319168 -101.846451470723 65.707515687627 -1.54999698900351 0.123181642829473 STAG3L5P other 1 1 1 2.97558973803597 -1.54999698900351 0.000535701672340615 180.002921284819 79.0131717292698 2.27813815526327 0.0243758459736606 -274.427314240921 176.573259169711 -1.55418388679771 0.122609651829923 MRPL20 essential 1 1 1 2.27813815526327 -1.55418388679771 3.45795048688119e-06 282.345192208044 60.8361005808757 4.64107971273888 7.33284047958483e-06 -82.8530199345435 111.509213711475 -0.743015013529928 0.458597245233864 ARPIN other 0.0299112717115223 1 0.0752642746824587 4.64107971273888 -0.743015013529928 0.017897435238768 13.6106538282342 5.42868784087916 2.50717194047209 0.0131939615644426 1.37660264706388 12.3417291261785 0.11154050076694 0.911331135567622 LINC00960 other 1 1 1 2.50717194047209 0.11154050076694 0.722021041918695 -1.19210145687959 7.80338247179598 -0.152767272549851 0.878781784301167 12.9754973005936 22.1343210444915 0.586216187725476 0.558588475335244 SERPINB10 other 1 1 1 -0.152767272549851 0.586216187725476 0.0854073770560864 -159.454379663528 173.078263574587 -0.921284835948288 0.358306303750671 -1169.5167349243 523.617441987828 -2.23353280686071 0.0269181276368959 HLA-DMB other 1 1 1 -0.921284835948288 -2.23353280686071 8.5482487179116e-05 73.4172920476759 26.3801693481498 2.78304854979352 0.00618189627994086 -76.4876395282841 57.6128771774883 -1.3276136043796 0.186614652329443 DECR2 other 0.6323994401511 1 1 2.78304854979352 -1.3276136043796 5.33941056083477e-05 140.529966265466 68.2227891123388 2.05986838260251 0.0410620680411357 -278.717279370537 106.150157270823 -2.62568880288553 0.00950289330319307 GNG10 other 0.405421443884184 1 1 2.05986838260251 -2.62568880288553 1.33908837456366e-05 18.1979139617415 5.15428708849305 3.53063646810989 0.000548972135115309 -8.56980870769498 8.80356645584734 -0.973447380749071 0.331877597970306 CCDC169 other 0.10918926606192 1 1 3.53063646810989 -0.973447380749071 0.018004953025064 4.59105169826763 1.66821569999411 2.75207318710874 0.00664288043625262 -2.29485745464465 7.89713916090625 -0.290593518473759 0.771758321549701 LINC00882 other 1 1 1 2.75207318710874 -0.290593518473759 0.124060846079102 12.9495662699213 14.0963534543849 0.918646535916222 0.359717064763615 -41.4805954586064 36.1997501881738 -1.14588071030827 0.253621989460379 ZNF702P other 1 1 1 0.918646535916222 -1.14588071030827 1.51013327693147e-09 211.503395771716 44.6486229963387 4.73706424919443 4.98475747761457e-06 -46.7622412093328 87.6252733712585 -0.533661572857027 0.59436561664868 AP5Z1 other 1.68923508357554e-05 1 0.0519660967041319 4.73706424919443 -0.533661572857027 0.12782861321538 6.4054554791815 3.42231694640443 1.87167219737238 0.0632255477478472 -10.4465197124121 15.6498950517407 -0.667513723119195 0.505483546029913 SOX2-OT other 1 1 1 1.87167219737238 -0.667513723119195 0.0108139827451632 5.76287525692613 4.18744460542411 1.37622722207748 0.171099290243609 -13.6110138088759 8.22173189632428 -1.65549229535945 0.100218374740791 STRC other 1 1 1 1.37622722207748 -1.65549229535945 0.0677288087203915 83.0121530202953 67.9629021388599 1.22143331741024 0.223877263844507 -119.328520684081 99.489420840342 -1.19940913994842 0.232298583444113 EIF4EBP3 other 1 1 1 1.22143331741024 -1.19940913994842 0.0638815360425322 96.5017639953597 80.0064173676371 1.20617529406329 0.229741699507765 -538.681476254828 309.354489577588 -1.74130809283025 0.0837801614460788 MRPL33 essential 1 1 1 1.20617529406329 -1.74130809283025 2.91521830810197e-05 799.590149198563 184.560633802866 4.33239815405395 2.7962051923949e-05 205.032418764072 276.410636298287 0.741767471432655 0.459470792111839 MICAL3 other 0.228985672132547 1 0.271707258545013 4.33239815405395 0.741767471432655 7.38069807126148e-28 302.792835337294 25.8176870856091 11.7281162457838 4.57980647331372e-23 -101.166883410296 89.1138938252293 -1.13525376423013 0.258044309249539 PPAN-P2RY11 other 1.06769178298869e-23 1 6.6027069925764e-19 11.7281162457838 -1.13525376423013 0.0709947538813696 26.7100035855145 63.0561105713198 0.423591042065687 0.672496112947988 -180.392279192064 100.621349741897 -1.79278333728166 0.0751067508352782 PCDHAC2 other 1 1 1 0.423591042065687 -1.79278333728166 6.00056070218614e-05 416.138815757444 92.9585795506824 4.47660471759423 1.46792754705988e-05 -34.5632997906546 415.02995523312 -0.0832790485478105 0.933737811003672 STON1 other 0.452262260123769 1 0.146528527747517 4.47660471759423 -0.0832790485478105 3.19971802453476e-12 40.4502798814619 6.37961221893926 6.34055464396042 2.77490492467031e-09 -5.92196904840304 10.8967190719208 -0.543463496610008 0.587651051820483 MRPS31P5 other 3.9999675024709e-08 1 3.44948431185766e-05 6.34055464396042 -0.543463496610008 0.544445594037409 8.0720959661098 14.0274197498452 0.575451231235801 0.565837077720576 -8.80000485535572 21.150287001355 -0.416070233694319 0.677945474586324 TICAM2 other 1 1 1 0.575451231235801 -0.416070233694319 0.00182328603278086 18.4489967626483 5.09335304939022 3.62217120701205 0.000393202240109705 14.0001494819383 8.11799289725934 1.72458262271513 0.0865583337104259 PALM2 other 1 1 1 3.62217120701205 1.72458262271513 0.00365186091007168 104.76727378185 59.0443444785939 1.77438287624367 0.0780149813698165 -152.146066158505 110.407303673735 -1.37804349074689 0.170228491740344 C4orf48 other 1 1 1 1.77438287624367 -1.37804349074689 4.29527014493649e-06 43.5395163584639 17.580285309344 2.47661033893019 0.0145186899669938 -115.886321479374 37.2461946883493 -3.11136003151548 0.00227954824038751 NAT6 other 0.0368061698719608 1 1 2.47661033893019 -3.11136003151548 0.625294479045276 -39.7820849831962 53.6763329074018 -0.741147593890684 0.459762664587018 -139.135256285325 166.008862815179 -0.838119446913067 0.40329714158417 AMY2A other 1 1 1 -0.741147593890684 -0.838119446913067 0.348802003895332 -97.1321987342476 70.6380548761963 -1.37506898943475 0.171760082667106 -253.623104619439 242.42248336159 -1.04620289794302 0.297642496656508 TNFRSF6B other 1 1 1 -1.37506898943475 -1.04620289794302 0.199954289626709 685.854351864137 394.233441214918 1.73971632074267 0.0839197929381602 -38.4639555968343 1446.15792859873 -0.0265973410207724 0.9788155535728 UPK3B other 1 1 1 1.73971632074267 -0.0265973410207724 0.029701932228604 90.7608463506097 80.0565089583307 1.13370976990579 0.258774451843937 -303.542470674911 171.799758162953 -1.76683875414422 0.0793447666848733 IL10RB other 1 1 1 1.13370976990579 -1.76683875414422 0.25331574371163 -737.359285620712 1015.94895172937 -0.725783794909736 0.469227672868803 -5138.77076983538 3090.3580448528 -1.66283993480766 0.0986644842936274 CFB other 1 1 1 -0.725783794909736 -1.66283993480766 2.50167861139474e-07 3049.39072663591 646.178822914123 4.71911275718359 5.20548186416347e-06 -7899.8625396119 2553.64104554626 -3.09356812438062 0.00234158506696692 NME2 other 0.00240561415271718 1 0.0541630387966209 4.71911275718359 -3.09356812438062 0.0313760124617384 14.0345791842859 6.2761871058412 2.23616328634052 0.026797319315171 -29.6313054153595 29.7107400289353 -0.997326400705656 0.320191144387749 DUBR other 1 1 1 2.23616328634052 -0.997326400705656 2.07587982211306e-05 172.262592066159 48.6131777627959 3.54353695836754 0.000560387547824135 -72.6860162811734 72.6393333481893 -1.00064266742042 0.318980161071096 PLA2G4B other 0.165904315383276 1 1 3.54353695836754 -1.00064266742042 0.345407975838382 -7.56917841041338 42.5268710173369 -0.177985782385157 0.858965054055667 176.173986093318 136.025654580337 1.29515264335133 0.19718100155841 LEFTY1 other 1 1 1 -0.177985782385157 1.29515264335133 0.00213021359498883 60.7797623387038 19.7571439397838 3.07634355066449 0.00248859053469204 -75.2117876291529 89.6392521874061 -0.839049699699747 0.402767770859388 CFAP57 other 1 1 1 3.07634355066449 -0.839049699699747 3.20679157543622e-16 146.438882271972 20.4030472566986 7.17730446974749 2.87709190974837e-11 -216.156718706539 60.4518264021193 -3.57568549325023 0.000467876054371196 TTC4 essential 4.38368408362131e-12 1 3.80121383115954e-07 7.17730446974749 -3.57568549325023 0.0295932736462113 33.8352568454404 59.6283393550876 0.567435840262982 0.571272061018856 -379.545680840996 175.913671970008 -2.15756783762496 0.0325642267398383 TMEM35B other 1 1 1 0.567435840262982 -2.15756783762496 0.414557671113761 -35.7215305718275 50.54180567456 -0.706771950369944 0.480776233668883 -198.307450645208 150.417227115774 -1.31838257125012 0.189333058492886 HLA-L other 1 1 1 -0.706771950369944 -1.31838257125012 3.32277596519801e-08 74.9581511555276 16.9572280639139 4.42042478127918 2.05794584653182e-05 -37.6522709021147 25.9086001251309 -1.45327307227196 0.148557663861053 JMJD7 other 0.000342378835454003 1 0.20276940425878 4.42042478127918 -1.45327307227196 3.51242804630923e-06 89.0140931222627 17.026073341945 5.22810464483141 5.65395446077135e-07 78.8078507172977 34.1389450289975 2.30844423137149 0.0223405476210192 APOBEC3D other 0.0303579156042507 1 0.00627532405601012 5.22810464483141 2.30844423137149 0.472746755887286 -9.06967571533383 12.1101117246363 -0.748934107427173 0.455054325860745 -44.0575553925166 38.4496642004723 -1.14585019944011 0.253657923002091 WDR86-AS1 other 1 1 1 -0.748934107427173 -1.14585019944011 0.228282473403625 -37.8414560998309 35.2919405743448 -1.07224072929952 0.28547000655146 -148.175090489158 88.1725083216473 -1.6805134991581 0.0951033703161972 TUBA4B other 1 1 1 -1.07224072929952 -1.6805134991581 0.000607232061248264 301.238082662089 129.353026071401 2.32880584096896 0.0212133898196994 -480.372827809324 252.14682825569 -1.90513135196847 0.0586895385511897 MRPS6 essential 1 1 1 2.32880584096896 -1.90513135196847 9.06937968603792e-15 459.450047702617 54.3879721855332 8.44764070510479 2.84458005093246e-14 -265.29814725386 210.628738852798 -1.25955341468986 0.209854168490682 ZNF512 other 1.21121565707036e-10 1 3.93519204245996e-10 8.44764070510479 -1.25955341468986 0.333266383917179 24.0790362780393 41.7307849247636 0.577008947266422 0.564804177853437 -123.629160897258 124.678479420025 -0.991583803976054 0.323008143719303 GSTA1 other 1 1 1 0.577008947266422 -0.991583803976054 0.0208054150129642 80.2482112015786 135.227982984132 0.593429033183132 0.55385158770466 -683.383337445514 310.878713533116 -2.19823136064515 0.0295753155250048 ACY1 other 1 1 1 0.593429033183132 -2.19823136064515 0.154048302300922 8.01489545804952 11.5555798428517 0.693595264542917 0.488960952869132 68.6746314679925 35.3255185495216 1.9440516172953 0.0536770457732624 MT1HL1 other 1 1 1 0.693595264542917 1.9440516172953 5.78665407363762e-11 68.3481544270633 15.224340258377 4.48940008349167 1.38658044223017e-05 -94.0742082145336 34.9339896058571 -2.69291338538559 0.00786255154145142 FAM86DP other 6.91852361044114e-07 1 0.138727373245128 4.48940008349167 -2.69291338538559 8.51132184450521e-10 1301.02906720824 305.539098153147 4.25814265693786 3.56005197030722e-05 -1199.45261969163 674.433096620176 -1.77846049623382 0.0772885791532369 DDOST essential 9.6450299141933e-06 1 0.342014192787415 4.25814265693786 -1.77846049623382 1.37089647321156e-05 44.3445164455771 10.1041372504375 4.38874842517178 2.19124832893909e-05 -0.501436033674963 25.7984130864059 -0.0194367006992065 0.984519638541968 LINC01011 other 0.111686935672545 1 0.21511484845195 4.38874842517178 -0.0194367006992065 0.578205820754134 2.22122077458503 4.3978582459048 0.505068751739187 0.614251807212344 -8.05265036587546 13.1385916519152 -0.61290057406584 0.540870220976409 GSTA2 other 1 1 1 0.505068751739187 -0.61290057406584 5.12604344262526e-05 137.727114716107 65.8886603906913 2.0903007270059 0.0382023444812855 -267.330243337195 102.518407028462 -2.6076316545084 0.00999649908526429 DNAJC25-GNG10 other 0.389886864246077 1 1 2.0903007270059 -2.6076316545084 4.51262357545106e-07 48.1638655462185 14.6233818112957 3.29362018770615 0.00123559428468734 -79.672932330827 34.3739454583687 -2.31782913681879 0.0218195377821732 FLNB-AS1 other 0.00424412247271172 1 1 3.29362018770615 -2.31782913681879 1.61285374548826e-15 122.256394855461 16.5762808257181 7.3753814948514 9.67319217596618e-12 -87.0477478867496 57.2156957601216 -1.52139630096783 0.130224438351217 P2RY11 other 2.18251368839472e-11 1 1.28962998089981e-07 7.3753814948514 -1.52139630096783 0.137525737014135 -38.9077256317685 120.351107115215 -0.323285149296726 0.74701521956012 -352.226529138731 186.522359220209 -1.88838770113823 0.0612731383902488 TMEM141 other 1 1 1 -0.323285149296726 -1.88838770113823 0.0125617528599948 3.65815353365206 1.83392190140166 1.99471609497446 0.0478270082517832 -9.72581477536391 6.045152874689 -1.60886167429873 0.109681488660529 TMEM225B other 1 1 1 1.99471609497446 -1.60886167429873 0.11868516530111 6.53929185833436 48.6829015141287 0.134324201207205 0.893323911450927 -137.002776842814 84.1593430747942 -1.62789741266227 0.105617695831906 IFITM10 other 1 1 1 0.134324201207205 -1.62789741266227 1.21103073765632e-05 274.285604464181 62.9835699862794 4.35487547822285 2.40140512528984e-05 -195.954069404625 276.602582378136 -0.708431814771496 0.4797343777616 DBNDD2 other 0.0991955277214293 1 0.234713336945829 4.35487547822285 -0.708431814771496 0.882340553369067 44.4710335401115 89.1836142004516 0.498645787556413 0.618754538808107 7.82819308636785 377.256079108654 0.0207503431220077 0.983472203878407 ETV5 other 1 1 1 0.498645787556413 0.0207503431220077 0.259563790153118 -7.54809446848443 4.88836751594981 -1.54409308298863 0.124687023189145 -16.8108075699912 18.9906965996985 -0.885212792576448 0.37746818831627 CFHR1 other 1 1 1 -1.54409308298863 -0.885212792576448 0.700771391743599 4.13785036993827 4.91825234800906 0.841325348345189 0.40145349522164 5.31232849804466 10.0723105742299 0.527419052350935 0.598651909238396 LILRA6 other 1 1 1 0.841325348345189 0.527419052350935 0.00388139058839969 400.720901639344 117.918205537927 3.39829545243932 0.00088489880682064 318.147072599531 182.001133319139 1.74804995330255 0.0826633741920247 SCARF2 other 1 1 1 3.39829545243932 1.74804995330255 1.16161921919221e-06 789.402901813022 144.250862111539 5.47243108469351 1.82041204390821e-07 773.159510003019 289.237110231357 2.67309927617717 0.00834756988130121 APOBEC3C other 0.0105393711757309 1 0.00208418974907051 5.47243108469351 2.67309927617717 0.0970026393980211 10.3381906925678 11.3975379138131 0.907054731534476 0.365785837980377 -36.0106840161901 25.1495752195679 -1.43186052654168 0.154197159054098 CCDC13 other 1 1 1 0.907054731534476 -1.43186052654168 3.65453419010376e-10 393.895706227696 64.507990968998 6.10615367663518 8.06151099209628e-09 -508.312420858754 311.780371426066 -1.63035414491862 0.105083603744782 UBE2V1 other 4.2195251758938e-06 1 9.84874797904403e-05 6.10615367663518 -1.63035414491862 0.00716233603285417 18.4628067973291 6.65070636387864 2.77606705020152 0.00619877694029199 -26.0632279666632 26.0065905519326 -1.0021778100677 0.317860998500515 CTAGE8 other 1 1 1 2.77606705020152 -1.0021778100677 0.0593807872265612 -1152.13581724176 489.087216993297 -2.35568581065072 0.0199839578939848 -767.777140819569 1519.87013644862 -0.505159699113229 0.61430201179307 C4A other 1 1 1 -2.35568581065072 -0.505159699113229 0.215544012857249 -270.548467522832 167.53793002494 -1.61484905228659 0.108364159486369 -119.731819223341 260.689946902258 -0.459288210558548 0.646666566285304 HBB other 1 1 1 -1.61484905228659 -0.459288210558548 6.37066448764216e-17 474.832401922431 69.7928693464728 6.8034515039813 2.16689149241862e-10 -270.757786595135 117.550867353606 -2.30332444745529 0.0226073321219303 N4BP2L2 other 8.783872195561e-13 1 2.79333982287684e-06 6.8034515039813 -2.30332444745529 4.15707743247101e-06 265.555970149254 91.6361325574847 2.89793952164739 0.00430821023023033 -342.60690095717 137.38674174219 -2.49374063765251 0.0137041370988165 MIR4712 other 0.0356801956028987 1 1 2.89793952164739 -2.49374063765251 0.000115418743288071 27.9708474309545 6.58017257561764 4.25077718092052 3.72862937498585e-05 -9.93849502976892 26.9499896255984 -0.368775467740026 0.712815075479217 LIFR-AS1 other 0.840594707367021 1 0.357053548948645 4.25077718092052 -0.368775467740026 1.74522949100637e-05 168.695925819033 38.3045209864878 4.40407350031976 2.04199475509058e-05 16.7442350617337 63.5444963573008 0.263504095895 0.792533599110171 LINC00847 other 0.140456069436193 1 0.201299842956829 4.40407350031976 0.263504095895 0.152685516669126 177.789524554702 128.227774979404 1.38651337109498 0.167620469112868 -60.2426243844065 221.285986120985 -0.272238768665042 0.785807889901482 IGFBP7-AS1 other 1 1 1 1.38651337109498 -0.272238768665042 0.931673392368892 5.35897460697582 14.739028324373 0.363590766571364 0.716665526235342 1.23175027517 64.2895827729553 0.0191594068905385 0.984738903012734 A2M-AS1 other 1 1 1 0.363590766571364 0.0191594068905385 1.37086625541933e-15 76.4056515888624 8.89725036024179 8.58755778417659 8.85187182386497e-15 36.5647241486389 14.3535493687978 2.54743431113453 0.0118254907486558 SMARCA5-AS1 other 1.85670125633995e-11 1 1.23200352044553e-10 8.58755778417659 2.54743431113453 8.77189978609952e-10 38.6823454497031 5.58933054936849 6.92074750420219 1.22081167062931e-10 -34.624037137704 51.936478525282 -0.666661239283858 0.506012666344906 RNF139-AS1 other 9.92803617790743e-06 1 1.58620060364866e-06 6.92074750420219 -0.666661239283858 0.000229470877237479 37.7764448921886 18.9772964960926 1.99061256696742 0.0483045548075701 -33.6744791446205 26.7788146928075 -1.25750446877192 0.21048704783387 SCAMP1-AS1 other 1 1 1 1.99061256696742 -1.25750446877192 6.85103392413574e-07 3.71756480663507 7.11791637409992 0.522282731525511 0.602223967038247 -53.9406410992006 12.0671145593727 -4.47005295539388 1.50827629154737e-05 BDNF-AS other 0.00633789148321797 0.218639731222707 1 0.522282731525511 -4.47005295539388 3.45365231834046e-08 5.31574895289909 0.918427697502467 5.78787962008823 4.06562864798633e-08 -13.1165769916831 8.61031147722665 -1.52335685258019 0.12978904501552 DDX11-AS1 other 0.000355415360080417 1 0.0004817363384999 5.78787962008823 -1.52335685258019 6.55764017596864e-19 104.740200305101 11.6964644289214 8.95485990160524 1.27448300806182e-15 -73.9219486169825 47.7555760622341 -1.54792287544912 0.123762244774492 ZNF585B other 9.20430375098959e-15 1 1.78580559089622e-11 8.95485990160524 -1.54792287544912 0.948831249910115 -0.535471948859483 3.07518985943996 -0.174126468066919 0.861996256985467 -1.58762131566567 4.91285226700539 -0.323156738566739 0.747017782934048 LINC02202 other 1 1 1 -0.174126468066919 -0.323156738566739 4.13201721685978e-05 92.0978119394707 21.4758384401343 4.2884384791868 3.16329881268118e-05 -27.8806437408078 99.4449592199931 -0.280362563969984 0.779575621884017 CEBPA other 0.317504202943506 1 0.305954261162524 4.2884384791868 -0.280362563969984 9.56730321838775e-09 46.8604183427192 10.3548726459452 4.52544613004671 1.20825492041562e-05 -23.1899321917021 15.0362286290852 -1.54227052299835 0.125087207369997 RAD51-AS1 other 0.000102111827249852 1 0.121792095977895 4.52544613004671 -1.54227052299835 1.97844095674172e-05 64.2870949205079 33.8353500620867 1.89999792532199 0.0592903848188591 -132.196980514392 49.6231007877937 -2.66402095829751 0.00853771406938646 LINC01184 other 0.158314845358472 1 1 1.89999792532199 -2.66402095829751 7.50051438090079e-08 71.9710839523926 12.870177753237 5.59208158055866 9.88954695789623e-08 -19.4109753175173 45.9652442427587 -0.422296794834834 0.673393593344444 RAB30-AS1 other 0.000754326731287192 1 0.00114946204291628 5.59208158055866 -0.422296794834834 1.60704669113667e-10 112.13601504697 15.4999582389953 7.23460110781811 2.14569839199317e-11 46.4026519245157 61.4477308406111 0.755156476727827 0.451323626374847 NUDT16P1 other 1.88554788271065e-06 1 2.84262122971255e-07 7.23460110781811 0.755156476727827 0.000127832239745992 45.8099641626413 10.5103235485102 4.35856840669141 2.43655826510775e-05 49.2544561164479 38.9009731065592 1.26614971768259 0.207448786696755 KCTD21-AS1 other 0.924354925603265 1 0.238051742501027 4.35856840669141 1.26614971768259 0.00906098644439499 -9.52675185118294 4.30472473905145 -2.21309199279538 0.0283718426508076 -20.8690852447173 7.12706186172888 -2.92814706110252 0.00393120205894131 LINC01550 other 1 1 1 -2.21309199279538 -2.92814706110252 0.909584689792976 0.705673851286197 1.94536596527393 0.362746066232751 0.717315618071444 -4.75787745315228 18.2853313587528 -0.260201872189469 0.795072168702189 CASC8 other 1 1 1 0.362746066232751 -0.260201872189469 1.03400052650419e-06 44.9576981707317 8.97225187355519 5.01074856171169 1.48914390898312e-06 -22.7889989837399 39.5673476388694 -0.575954678381142 0.565497597034929 UBR5-AS1 other 0.00942284679803265 1 0.0160931782243806 5.01074856171169 -0.575954678381142 1.35145902228736e-09 19.0477088712482 13.9088242445132 1.36946937687865 0.172846319254493 -94.7044086164428 21.9304682728855 -4.3183942740308 2.80366195483895e-05 SBF2-AS1 other 1.5157964393975e-05 0.405073079235131 1 1.36946937687865 -4.3183942740308 5.43351325428347e-05 14.9441872768152 5.72575200079661 2.60999555599615 0.00995998646987817 -6.62385046069746 10.4847921848112 -0.631757916031285 0.5284940809744 EXTL3-AS1 other 0.411805969542145 1 1 2.60999555599615 -0.631757916031285 0.00169406952474958 20.1295806847667 8.81260361941178 2.28418087935178 0.0237735103528776 -49.3897883767487 29.8779149843212 -1.65305338082214 0.100425511017009 LACTB2-AS1 other 1 1 1 2.28418087935178 -1.65305338082214 0.0153423813713164 4.82204399512916 1.83759147380351 2.62411099739613 0.00960469523329581 -2.06306121823231 8.21277726806977 -0.251201408596971 0.802009201672108 CACNA1C-AS1 other 1 1 1 2.62411099739613 -0.251201408596971 0.170070714100968 -11.7734493192132 63.3102670158566 -0.18596429732739 0.852724006016876 -441.13463292952 240.081109511831 -1.8374399961184 0.0681236880143331 H2AFJ other 1 1 1 -0.18596429732739 -1.8374399961184 1.89713146268248e-05 4.56289661820228 2.37973724276148 1.91739513766967 0.0570035799070731 -7.01931882078879 3.44142183484357 -2.03965661800593 0.0430609421495008 RGMB-AS1 other 0.152149943307135 1 1 1.91739513766967 -2.03965661800593 0.00336650661026954 201.466122358071 68.3717186759674 2.94662948744751 0.00370242005153888 53.8582472716192 103.376968689482 0.520988842625051 0.603108588111983 STARD4-AS1 other 1 1 1 2.94662948744751 0.520988842625051 0.00042405200092656 40.4083431995461 13.1627015659326 3.0699125857362 0.0025287967075292 -25.365028304293 21.7935402067592 -1.1638782897891 0.246261769955812 UBAP1L other 1 1 1 3.0699125857362 -1.1638782897891 5.48385611890017e-13 211.149939659285 56.9663609505231 3.70657237246864 0.000296908837315258 -459.952344868233 109.496143937386 -4.20062596114116 4.59576471971786e-05 PGAM5 other 7.01988421780411e-09 0.661698204344978 1 3.70657237246864 -4.20062596114116 7.30397865482936e-05 20.8910351980294 4.95197652819565 4.21872661937707 4.19304162816857e-05 -2.78461139560507 21.0174576028185 -0.132490401466619 0.894770497676251 BAALC-AS1 other 0.545753285088849 1 0.399471075915619 4.21872661937707 -0.132490401466619 0.482157503258119 4.15367553253174 15.3224458231014 0.271084367370993 0.786701332960115 -22.4353133335911 26.4710177141513 -0.847542530319761 0.398052150213853 MIR210HG other 1 1 1 0.271084367370993 -0.847542530319761 3.35764344984349e-07 17.8974192724849 3.49895809469557 5.11507105489986 9.44632251483345e-07 -1.27560921743392 6.04615079802262 -0.21097873011224 0.833190219520581 UBL7-AS1 other 0.00319169143973502 1 0.0103380553602337 5.11507105489986 -0.21097873011224 0.0600410436149057 -12.6967420626687 18.9576214180265 -0.669743412567335 0.504011482181565 -65.4719651379955 29.5419199418824 -2.21623933944706 0.0281224700239519 ZBED5-AS1 other 1 1 1 -0.669743412567335 -2.21623933944706 2.1191902023357e-06 244.1979784595 48.9736155885044 4.98631713270565 1.68021549657632e-06 10.5867051355138 176.592200473968 0.0599500153862937 0.952275242574084 ZCCHC3 other 0.0187527141004686 1 0.0181026417601133 4.98631713270565 0.0599500153862937 1.71640781716678e-09 42.7631197059798 6.38651202492561 6.69584892960064 3.96208904397722e-10 21.7857706200609 11.9283953696933 1.82637898433619 0.0697682677288299 DNAJC3-AS1 other 1.91448127926783e-05 1 5.05998391806331e-06 6.69584892960064 1.82637898433619 2.82662486051894e-09 13.1989441735817 7.28340309704385 1.8121946564977 0.0718915596258806 -34.2954376674954 10.2387926370906 -3.3495587695817 0.0010164317178042 CKMT2-AS1 other 3.11494059629187e-05 1 1 1.8121946564977 -3.3495587695817 0.000614026490646622 78.8525328651001 65.9541550066647 1.19556581169347 0.233858779488983 -423.008411098178 150.784624102416 -2.80538160715154 0.00573097543793044 TWF2 other 1 1 1 1.19556581169347 -2.80538160715154 5.64167514660082e-05 35.1822832919164 12.346238817043 2.84963573224828 0.00500578419434816 -101.90929688642 40.7475950632782 -2.50098924189666 0.0134815026557891 MARS2 essential 0.426792724840352 1 1 2.84963573224828 -2.50098924189666 0.0395311668912077 19.9917953667954 7.77808498151275 2.57027217037519 0.0111699925009916 16.434555984556 15.2247088793027 1.07946602558017 0.282172345025736 LRP4-AS1 other 1 1 1 2.57027217037519 1.07946602558017 1.17833122775335e-16 36.3463437813255 4.3136742774854 8.42584336305363 2.44474185881026e-14 8.07292041849831 8.2318792555785 0.980689848314712 0.328293889894181 STX18-AS1 other 1.61949843942421e-12 1 3.38572300026633e-10 8.42584336305363 0.980689848314712 0.0704873924752932 2.40006503360066 7.07582334847004 0.3391923335847 0.734936108312834 54.8081364260424 24.0523136249766 2.278705378643 0.0240865948742181 PCED1B-AS1 other 1 1 1 0.3391923335847 2.278705378643 4.08247635111623e-08 61.9264072847683 17.013345755128 3.63987237878258 0.000372567145837205 -23.8043874172185 24.8590907696215 -0.957572730146194 0.339788920494295 TMEM161B-AS1 other 0.000417923104063769 1 1 3.63987237878258 -0.957572730146194 2.00164163736363e-06 6.89606020670043 3.05931310197699 2.25412044365255 0.0255902190972675 -9.8229104529375 4.61458412831774 -2.12866645829653 0.034862386383301 SEC24B-AS1 other 0.0177565629650528 1 1 2.25412044365255 -2.12866645829653 0.790781986056081 2.01117998902382 3.02049212863338 0.665845134956128 0.506506218316009 0.651556236873184 4.61564114785898 0.141162671880464 0.887925919149693 LINC00926 other 1 1 1 0.665845134956128 0.141162671880464 4.19610999134785e-06 36.6678752789106 20.2848821009044 1.80764547195844 0.0725882300317181 -130.439399476802 40.6864768756523 -3.20596447501356 0.00163305466434504 NRAV other 0.0360026237257645 1 1 1.80764547195844 -3.20596447501356 0.00028286514008243 5.38379629629627 11.8267260111502 0.455222881735861 0.649581826751476 -49.4558641975309 17.6909316895323 -2.79554887585677 0.00583250206737064 FAM13A-AS1 other 1 1 1 0.455222881735861 -2.79554887585677 3.78140969113663e-19 80.3612763516605 10.3693466654367 7.74988810235484 1.18945954306155e-12 -47.5757567945555 21.2977682714615 -2.23383765792521 0.0269438384654097 UBA6-AS1 other 5.31704016670722e-15 1 1.61290714039147e-08 7.74988810235484 -2.23383765792521 7.50968383437928e-16 341.601522070014 61.9326576716569 5.51569293023163 1.4013490041684e-07 -600.0798173516 164.810219869875 -3.64103523328463 0.000368233254712401 BCKDHA other 1.02139209831393e-11 1 0.00161589553670658 5.51569293023163 -3.64103523328463 0.840337695251302 4.3767910680102 7.91752812140586 0.552797666253574 0.581224834038418 -0.570223668330011 39.138105412913 -0.0145695266113181 0.98839497135313 INSL3 other 1 1 1 0.552797666253574 -0.0145695266113181 0.397111606791409 -3.43127306273061 16.1406747849341 -0.212585477896711 0.831927829239431 -27.3882505870513 24.2175853624861 -1.13092408582883 0.259822684358614 ADH1C other 1 1 1 -0.212585477896711 -1.13092408582883 1.67557238043269e-05 133.701013654932 34.7772223395376 3.84449949307567 0.000176742378433836 -123.035734449026 103.983550984106 -1.18322305099807 0.238556010279463 TRIM39-RPP21 other 0.135101401034288 1 1 3.84449949307567 -1.18322305099807 0.00301558144794165 82.3194955042743 23.7144136474904 3.47128530049006 0.000738965017962249 50.9894140054039 40.0781098464336 1.27225096694377 0.205942732528365 TRIM52-AS1 other 1 1 1 3.47128530049006 1.27225096694377 0.000674460186054407 33.0550825856444 9.32254368820471 3.54571495625889 0.0005198540032169 16.2280354229783 13.6577949987978 1.18818853441619 0.236600261365175 MEF2C-AS1 other 1 1 1 3.54571495625889 1.18818853441619 0.615086401639967 15.6874046965538 23.5370699017809 0.666497774022704 0.506071221064336 -4.36500266849653 35.7207327489301 -0.122198015902327 0.902898471839843 APELA other 1 1 1 0.666497774022704 -0.122198015902327 4.59218544306581e-14 293.687837514934 45.4584240560453 6.46058114889441 1.71663004589161e-09 -157.312066905616 103.795461104996 -1.51559678266166 0.131942158135028 CDK11B other 6.04653057288475e-10 1 2.15042245848842e-05 6.46058114889441 -1.51559678266166 0.0675406378425614 39.9947933354691 63.5622038189206 0.629222886125982 0.530214130036969 -169.671068198063 101.254561508914 -1.67568814352256 0.0959998610891993 PCDHAC1 other 1 1 1 0.629222886125982 -1.67568814352256 2.18664960889881e-05 19.825602075495 4.38886568651664 4.51724967031976 1.23486325933119e-05 8.79192223937453 6.54996515847733 1.34228534452516 0.181466225572137 SEMA6A-AS1 other 0.17438530630968 1 0.124326032949464 4.51724967031976 1.34228534452516 0.000382009074522044 105.076070321129 49.1241409925915 2.13899048813853 0.0341591366360264 -240.350860382481 111.813858792845 -2.14956234385733 0.0332964206246598 ABHD14A other 1 1 1 2.13899048813853 -2.14956234385733 0.00375495906998818 1.90693382785291 0.678641788564592 2.80992691576848 0.0056119989745738 -5.34234022343842 4.11450705267604 -1.29841561942732 0.196124081305479 ZFAT-AS1 other 1 1 1 2.80992691576848 -1.29841561942732 1.72023871176339e-05 19.0984529238585 6.34403262621887 3.01045944261504 0.00304917927882421 -15.2870114876176 8.97844395406455 -1.70263484027176 0.0906539583326482 SRP14-AS1 other 0.138582430619659 1 1 3.01045944261504 -1.70263484027176 0.0105451730347509 11.7143723695139 3.82486594334547 3.06268835118121 0.00260074293270762 6.09605220999717 16.0334913196655 0.380207410130332 0.704329291582491 GDNF-AS1 other 1 1 1 3.06268835118121 0.380207410130332 0.000132688762780867 58.9485029940119 26.1932470005292 2.25052293031181 0.0258506474321912 -125.9325748503 59.7996700111138 -2.1059075213441 0.0368558653715298 TMEM110-MUSTN1 other 0.957349423463954 1 1 2.25052293031181 -2.1059075213441 5.87587352496797e-09 11.3415956291498 1.81766856032145 6.23963899510042 5.19540696148049e-09 -1.1038947550103 8.00183544517743 -0.137955193227024 0.890479874484594 DSTNP2 other 6.35181928049037e-05 1 6.39762413236708e-05 6.23963899510042 -0.137955193227024 0.00027726813740175 375.754925931253 93.6075405318189 4.01415231931585 9.39363584947572e-05 -119.935006472026 306.448307077579 -0.391371085113106 0.696078351670086 RBM14-RBM4 other 1 1 0.862053961906386 4.01415231931585 -0.391371085113106 0.000206320024219705 6.92451796518598 1.87129903050597 3.70038024511438 0.000303610920262641 -12.4884745786072 8.15652258698418 -1.53110280090877 0.127893184757816 OXCT1-AS1 other 1 1 1 3.70038024511438 -1.53110280090877 5.85688452939887e-05 4.26265088898138 1.22956820360132 3.46678685777363 0.000681742634149228 -8.02423473601448 4.40918545777221 -1.81989050196787 0.0707050120490174 ALG1L9P other 0.442194781969615 1 1 3.46678685777363 -1.81989050196787 1.28661628485982e-08 141.089023138571 25.8855645829657 5.45049047264807 1.90940126464743e-07 -142.656675937695 81.5862777763549 -1.7485376196319 0.0823255175933543 LY75-CD302 other 0.000136355593869444 1 0.00218263658561847 5.45049047264807 -1.7485376196319 0.0675999293533274 13.6514507980507 9.37730549325216 1.4557967433048 0.147566804642315 -31.8141756456685 26.3443243828201 -1.20762921012374 0.229116234116772 CCDC153 other 1 1 1 1.4557967433048 -1.20762921012374 4.92508161862248e-05 4.28322075761417 0.930665273453777 4.60232145733641 8.83523338709467e-06 2.85733128598411 3.77886926830939 0.756133934017367 0.450754754528423 NPHP3-AS1 other 0.375143466890474 1 0.090145886248527 4.60232145733641 0.756133934017367 0.0187674265752615 12.748844742985 6.42989905304647 1.98274415162779 0.0492223259067039 -26.256967271688 22.0827323564261 -1.18902710261972 0.23630788445189 C8orf34-AS1 other 1 1 1 1.98274415162779 -1.18902710261972 0.464219450664752 6.9416115200877 6.7010351392132 1.03590137581382 0.301904248205607 11.5376204088026 10.9309839373855 1.05549696851555 0.292883940691826 LINC01574 other 1 1 1 1.03590137581382 1.05549696851555 4.01692670125224e-06 19.0421678390965 4.25582202412523 4.47438067925562 1.62911748077589e-05 3.83592588923018 6.9175706012014 0.554519225082282 0.58015482682385 USP46-AS1 other 0.0345335188506655 1 0.161966859938739 4.47438067925562 0.554519225082282 0.0104384283140807 7.04075546719599 65.5439167915636 0.107420426057026 0.914601921436041 -929.367572343721 319.234687888081 -2.91123617703332 0.00416113113630283 TNFSF12-TNFSF13 other 1 1 1 0.107420426057026 -2.91123617703332 0.823216831915297 -0.305801271803632 9.01838013779869 -0.0339086695316744 0.972994467185565 22.6916190491806 37.4623206700224 0.605718456393935 0.545605124975291 C5orf17 other 1 1 1 -0.0339086695316744 0.605718456393935 0.0613282766991398 6.56407824177842 2.82437594043966 2.32408092272469 0.021411252515712 4.67952846859389 4.55545877236968 1.02723538998459 0.305899781171938 HHIP-AS1 other 1 1 1 2.32408092272469 1.02723538998459 0.0178795331203261 50.7355873030458 33.2959931471982 1.52377455986217 0.129615943708612 -70.5391749735862 53.5394882784949 -1.31751679445766 0.18962221560165 FMN1 other 1 1 1 1.52377455986217 -1.31751679445766 0.00183452575194639 177.096910066358 81.4662446620658 2.17386858570666 0.0312423309248486 -612.091625888974 272.552775328512 -2.24577286050825 0.0261416458629998 ATP5J2-PTCD1 other 1 1 1 2.17386858570666 -2.24577286050825 2.46308641356736e-06 28.940686057614 9.58955703854289 3.01793773594484 0.00298806813016136 -34.9385269489366 21.0978514972582 -1.6560229819362 0.0997938277068574 ZNF436-AS1 other 0.0216332879703622 1 1 3.01793773594484 -1.6560229819362 1.89066759799791e-21 149.82556976571 15.3879067270848 9.73657901772931 8.89640104377521e-18 -116.614870299832 67.0813002664222 -1.73841100033363 0.0841241788853731 HAUS5 essential 2.69268879306862e-17 1 1.26248827212214e-13 9.73657901772931 -1.73841100033363 0.0430329910437161 27.5938883635757 64.7575108977804 0.426111009843053 0.670672164959054 -211.551758296187 102.751161232251 -2.05887462252628 0.041333719729042 PCDHA11 other 1 1 1 0.426111009843053 -2.05887462252628 0.223553219738468 -12.2436035648593 9.67659803658027 -1.26527975209624 0.207707266795006 2.64918622525338 14.8191699628873 0.178767517471486 0.858358307679565 TMEM150C other 1 1 1 -1.26527975209624 0.178767517471486 0.527664113235519 1.5324313082626 6.37039792603631 0.240555036915266 0.810228466289698 -11.1528250131171 12.7732719248905 -0.873137679891107 0.383983656081011 APOBEC3B-AS1 other 1 1 1 0.240555036915266 -0.873137679891107 3.80089437761152e-07 17.9622532998555 6.03722543507477 2.97524972241376 0.00339694216430444 -22.3069508540115 10.3629542964575 -2.15256675035582 0.0329001303251761 UGDH-AS1 other 0.0035956460812205 1 1 2.97524972241376 -2.15256675035582 0.00796873428076446 43.1754055468341 32.2078772352955 1.34052316554162 0.182449709758343 -49.8099424385139 46.5011598656757 -1.07115483962972 0.286115373379947 NAIP other 1 1 1 1.34052316554162 -1.07115483962972 1.13189012948945e-08 50.833087342976 8.05431571143586 6.31128567145698 2.80655605553606e-09 16.9378464364197 23.9869494462874 0.706127574677543 0.481175695130688 ZNF286B other 0.000120240911095741 1 3.48826852142577e-05 6.31128567145698 0.706127574677543 0.00180187760633325 13.283091768867 10.0052903485269 1.32760682660476 0.186247493011234 -26.5561685440774 15.1232941419321 -1.75597778465775 0.0810547058189243 LINC01091 other 1 1 1 1.32760682660476 -1.75597778465775 2.3934434023783e-10 27.6203480701167 8.13137966668417 3.39676035338537 0.000891119640439864 -42.0229264337621 14.4088787265649 -2.91646055402538 0.00413352541645334 ZNF324B other 2.78572877602811e-06 1 1 3.39676035338537 -2.91646055402538 6.93669156781417e-15 50.0274363476734 8.3585558342094 5.98517702578765 1.47706225322557e-08 -14.8883732597517 12.6293973941017 -1.17886648073209 0.240281393155584 MIR302B other 9.28129331773536e-11 1 0.000178429120189649 5.98517702578765 -1.17886648073209 0.226856360411704 10.26537345678 19.316242460748 0.531437388904183 0.595876492470901 -44.9039001896083 38.8059926177098 -1.15713829644743 0.248995996542108 LINC01234 other 1 1 1 0.531437388904183 -1.15713829644743 0.0796120927380471 -29.1623130353267 15.8608763700558 -1.83863188609068 0.0678587681261008 9.73594125083416 25.3648952309193 0.383835263745392 0.70161986237615 MIR143 other 1 1 1 -1.83863188609068 0.383835263745392 5.21080073243908e-24 234.035525688851 25.0576610871078 9.33987912420375 1.50256968109907e-16 -61.0118180314474 47.8588108550821 -1.27482937710661 0.204394723246085 NOP14-AS1 other 7.48375201192901e-20 1 2.11862325034969e-12 9.33987912420375 -1.27482937710661 0.00593116905709699 -7.79667104686826 30.208548285909 -0.258094860205681 0.796689845111958 -146.920455540955 53.0613311242328 -2.76887994379503 0.00634001962845415 SRD5A3-AS1 other 1 1 1 -0.258094860205681 -2.76887994379503 8.49958815506642e-19 66.6619717396942 8.78889941483526 7.58479174618517 3.32113321928333e-12 -125.535429089966 37.137064379303 -3.38032720647486 0.000924491178493501 ZNF564 other 1.19164225934031e-14 1 4.47057742647729e-08 7.58479174618517 -3.38032720647486 8.74646021636612e-19 90.7165669540738 8.60655783268182 10.5404005547484 1.06709817874745e-19 61.5008798169981 43.982420452095 1.39830594098349 0.164127252430201 FER1L5 other 1.2260787931302e-14 1 1.52680407415185e-15 10.5404005547484 1.39830594098349 0.211989061068632 -12.5901791536002 7.13245144577259 -1.76519661568287 0.0795521580806566 -7.96312292358804 10.4169981926233 -0.764435471365165 0.445800721824726 ECSCR other 1 1 1 -1.76519661568287 -0.764435471365165 0.161094585795324 -67.8140077821011 44.0553734884822 -1.53929027068242 0.125785656514009 -16.9650583657587 64.037262876926 -0.264924789155402 0.791421664523156 VCAN-AS1 other 1 1 1 -1.53929027068242 -0.264924789155402 4.12399832571956e-05 542.386826931476 128.756437721423 4.21250258651131 4.91238967604254e-05 -244.764007396835 439.940338578607 -0.556357273778617 0.579002642093276 PDCD6 other 0.316929271331548 1 0.465105054527708 4.21250258651131 -0.556357273778617 0.773517790799356 -0.826253876946801 5.54684286876673 -0.148959308293964 0.881788521030271 -6.64111574110829 10.2756581085453 -0.646295903479455 0.519088670578763 GBA3 other 1 1 1 -0.148959308293964 -0.646295903479455 0.0764295670632569 -94.6713941955822 49.5763709452322 -1.90960718565236 0.0580311119146265 43.9089012020836 109.394211243574 0.40138230993153 0.688691503003423 TMEM158 other 1 1 1 -1.90960718565236 0.40138230993153 1.28255010754335e-06 244.928893554286 51.7711715233714 4.73098997660727 4.99257514516577e-06 -94.1731627491819 94.8936992077339 -0.992406909367347 0.322545784468235 C15orf38-AP3S2 other 0.0115852751214391 1 0.052042603313208 4.73098997660727 -0.992406909367347 0.118151501566041 3.27555130989609 3.92092460675617 0.83540277827632 0.404768604658609 -5.54539801555472 6.10897269142224 -0.907746407729265 0.365412340512606 SLC7A11-AS1 other 1 1 1 0.83540277827632 -0.907746407729265 0.4482156681476 -2.77608488820761 3.55650356067152 -0.780565755340743 0.436263916323038 -16.9930845534471 14.6035597331138 -1.16362618868296 0.24638698933331 LINC01018 other 1 1 1 -0.780565755340743 -1.16362618868296 0.00448908676735378 27.866142877478 17.9713207875107 1.55058958698482 0.123093448033934 -114.563278643883 58.4722177732101 -1.95927712350893 0.0519220670752719 YJEFN3 other 1 1 1 1.55058958698482 -1.95927712350893 0.0751663476252285 31.0804778843405 73.8610546839602 0.420796562103383 0.674539807858594 -215.962357602774 117.195813016893 -1.84274806448627 0.0674511641406359 PCDHA10 other 1 1 1 0.420796562103383 -1.84274806448627 0.000141054136780461 146.638552231011 71.1550231386686 2.06083205039844 0.0410695079320067 -297.222052541797 135.535274557448 -2.19294979489504 0.029872206309271 FZD10-AS1 other 1 1 1 2.06083205039844 -2.19294979489504 0.00541145234062904 -22.2080567941315 12.6923883192582 -1.74971457187732 0.0821990535916567 -78.7803105800646 24.71770436276 -3.18720174915418 0.00174622600889983 KIAA1456 other 1 1 1 -1.74971457187732 -3.18720174915418 4.06522956823182e-08 73.2807499397867 17.6956274005913 4.14117839853127 6.39690214787552e-05 -43.4682813668611 32.5919309523218 -1.33371298038309 0.184782562429705 ZNF718 other 0.000416238855491256 1 0.597982412783404 4.14117839853127 -1.33371298038309 4.20967540648989e-09 50.7282706247844 32.4832431442976 1.56167505810422 0.120471888822923 -249.923811350184 57.9867437264352 -4.31001631216356 2.94156673461472e-05 SMIM20 other 4.58812522553333e-05 0.424791652145712 1 1.56167505810422 -4.31001631216356 0.40872053716319 58.452481032528 63.5311710506072 0.920059870861917 0.358971150238331 -51.1057382052845 104.806477415693 -0.487620035187177 0.626507983912744 TUNAR other 1 1 1 0.920059870861917 -0.487620035187177 0.0307102189872574 126.746464916313 121.846652739214 1.04021294033892 0.299892761151248 -1574.05775574995 674.113293911478 -2.33500476843682 0.0208510602218517 CHCHD10 other 1 1 1 1.04021294033892 -2.33500476843682 0.027702976601185 34.6008297075787 16.3803282541745 2.11234043486037 0.0362395624324847 1.53309976727712 24.7828601365866 0.0618612927978328 0.950751974718425 FAM218A other 1 1 1 2.11234043486037 0.0618612927978328 0.000287037932265903 46.7774645508694 11.3477755310624 4.12217041329595 6.07915430626689e-05 20.2909589290243 52.7736466854883 0.384490369785339 0.701138660486086 CDK3 other 1 1 0.56943438386802 4.12217041329595 0.384490369785339 0.07763330026797 32.0791771706297 17.5562873002276 1.82721874061686 0.0697813983737191 -57.4992732393086 78.2889826546734 -0.734449104964532 0.463894726061456 GPR162 other 1 1 1 1.82721874061686 -0.734449104964532 8.39184063023447e-06 159.682042501763 35.3913229982222 4.51189808614343 1.52833779080314e-05 -135.505480578776 152.236417033051 -0.890098986954991 0.375223885246002 GLI4 other 0.0698872487685927 1 0.152405844498889 4.51189808614343 -0.890098986954991 0.356454393882742 18.3138867249488 12.9340684587413 1.41594168790498 0.158838451086402 11.8997085893995 22.0914996130529 0.538655537099371 0.590912550585193 CCDC169-SOHLH2 other 1 1 1 1.41594168790498 0.538655537099371 2.82574991314422e-05 2805.38373438496 600.848255379179 4.66903866204048 6.83169708133955e-06 -621.35838430113 2693.83295512979 -0.230659582331523 0.817904400456588 SELENOP other 0.222443033162713 1 0.0703528165436346 4.66903866204048 -0.230659582331523 1.44778944824765e-05 19.5037439087199 4.85606337319699 4.01636931189381 9.26221458919428e-05 -22.573338021473 15.6137618849561 -1.44573346178813 0.150310663100858 NT5C1B-RDH14 other 0.117560503197709 1 0.850641787871603 4.01636931189381 -1.44573346178813 0.00312016438102703 366.900790222315 137.752095221638 2.66348609530755 0.00862086742810618 -506.948536508272 399.267069284533 -1.26969784264126 0.206254619083658 LINC02381 other 1 1 1 2.66348609530755 -1.26969784264126 0.191012653257854 36.8619071950514 20.2744651309218 1.81814449639074 0.0710239613485866 20.3410278903199 82.7582470656167 0.245788529984113 0.806179702492106 SNHG18 other 1 1 1 1.81814449639074 0.245788529984113 9.54000068549042e-09 58.1886355117309 11.8199058806357 4.92293560535539 2.14979003643108e-06 -4.07425625176903 19.0644216874839 -0.213709931439664 0.831052324783018 SMAD1-AS1 other 0.000101849047318296 1 0.0230092027599218 4.92293560535539 -0.213709931439664 5.25918831507874e-09 14.9284304974867 2.42725916181229 6.15032409079076 7.22844948515192e-09 1.22141839307247 5.48821821316761 0.222552811428304 0.824198918604092 GLUD1P3 other 5.70201197120837e-05 1 8.85340492941407e-05 6.15032409079076 0.222552811428304 1.04526475958774e-07 37.9305054839521 7.81987026328707 4.8505287436838 3.03567035434209e-06 -20.0644678775314 13.683333291824 -1.46634357649684 0.14463415221199 SNHG21 other 0.00103867959160234 1 0.0321507847228371 4.8505287436838 -1.46634357649684 1.82254254655027e-12 220.66178295272 48.3583719436724 4.56305235440403 1.03261009539649e-05 -185.112882369521 74.058148354694 -2.49956131070063 0.0134969737571407 THAP9-AS1 other 2.29549233738007e-08 1 0.104716989774158 4.56305235440403 -2.49956131070063 0.000285401827382416 114.924778398522 39.781709116682 2.88888489082862 0.00443132209633284 -40.6936391802942 59.9821335803068 -0.678429338059669 0.498531076558128 TMED7-TICAM2 other 1 1 1 2.88888489082862 -0.678429338059669 3.48598195597464e-23 39.7082698851353 3.7452937764992 10.602177627372 5.98852785717769e-20 -21.5162991371045 15.6903258601138 -1.37130989687096 0.172326347942648 ZNF345 other 4.99506354471606e-19 1 8.57437418590701e-16 10.602177627372 -1.37130989687096 0.365274600490547 2.05537091744625 2.03902150873426 1.00801826201536 0.315037211536367 -6.72189397669458 8.10670463630503 -0.829177116752384 0.40829593376412 ALG1L2 other 1 1 1 1.00801826201536 -0.829177116752384 0.000740061957498407 270.460078420949 69.4131459966853 3.89638121911178 0.000151646373119127 259.697840101019 110.811523536485 2.34359958073777 0.0205264360862055 SHANK3 other 1 1 1 3.89638121911178 2.34359958073777 3.32502483751612e-09 80.2391395664472 14.232987554466 5.63754723029109 8.01912938637553e-08 4.67575272771386 28.6540487220931 0.163179478511486 0.870591064193838 ZNF550 other 3.6508772715927e-05 1 0.000936072973271616 5.63754723029109 0.163179478511486 9.05107187892446e-05 93.2903431486205 38.344050714148 2.43298090345469 0.0161279474819427 -94.3632263478079 61.295155423416 -1.53948914389667 0.12575054348233 LINC00958 other 0.667245018914311 1 1 2.43298090345469 -1.53948914389667 2.83299641740166e-05 74.0504664375394 15.784557480157 4.69132356295888 5.97446922627399e-06 1.39363389643947 65.2459371409911 0.0213597038759355 0.982986548625517 RPL32P3 other 0.222928488085337 1 0.0618716033072934 4.69132356295888 0.0213597038759355 0.0667644114009543 -45.2484638357765 65.4590488076915 -0.691248416528469 0.490450144240817 -193.158885723113 92.9345843925903 -2.07843922674833 0.0393277999702682 FOXD1 other 1 1 1 -0.691248416528469 -2.07843922674833 0.284542856159267 10.7622937675322 8.21019418830188 1.31084521519194 0.191968191466928 -3.27818694382017 14.1763959609875 -0.231242619974888 0.817450076624225 LINC00605 other 1 1 1 1.31084521519194 -0.231242619974888 0.520193975239182 931.978787621168 3168.16791419334 0.294169631428283 0.769046093920466 -9774.31258856202 9973.64642256686 -0.980013946197871 0.328700376656443 MALAT1 other 1 1 1 0.294169631428283 -0.980013946197871 2.33462718068814e-10 53.1338248601819 9.47066237880318 5.61035994473878 1.20596346995894e-07 -9.95868504205669 17.2687522416297 -0.576688164999516 0.565170874565435 ABCA11P other 2.71914027734748e-06 1 0.00139578212013048 5.61035994473878 -0.576688164999516 0.0613918725890081 3.37452384168501 69.2767314978069 0.0487107830973787 0.961218227832993 -233.186627043092 109.921837777407 -2.12138581157365 0.035626244060738 PCDHA12 other 1 1 1 0.0487107830973787 -2.12138581157365 1.06261686554827e-07 39.977199067493 10.1004814669332 3.95794984609097 0.000116345347272534 -25.4139563313811 18.8248288130415 -1.35002323706523 0.179042160097714 FAM86EP other 0.00105528480917599 1 1 3.95794984609097 -1.35002323706523 0.715142957016884 -2.78282089676034 5.32109709521625 -0.522978785570769 0.601726300663718 -9.47102183184979 11.8702500444819 -0.797878881772382 0.426145932067508 SCARNA5 other 1 1 1 -0.522978785570769 -0.797878881772382 0.0511049557094905 315.569064788418 172.328619346975 1.83120520540489 0.0691512640011015 -140.522037412528 298.56963142232 -0.470650805117427 0.63860721962653 PCDHGA12 other 1 1 1 1.83120520540489 -0.470650805117427 0.277258803485674 -0.711997419909704 26.4360374401152 -0.0269328344507973 0.978550336598946 -74.7604293177289 55.9372683807354 -1.33650482910381 0.183477726459539 HOXA10-AS other 1 1 1 -0.0269328344507973 -1.33650482910381 0.000685964805357751 6.65869744435286 3.66790285904776 1.81539634506066 0.071785826572963 -6.11744984885957 5.29739609068897 -1.15480317954928 0.250305724262973 GUSBP3 other 1 1 1 1.81539634506066 -1.15480317954928 0.0930892454152464 7.71247448400997 3.88553131000853 1.98492146084213 0.0490016091966713 -3.70680426400544 15.5353780614049 -0.238604059029267 0.811742678919936 C8orf88 other 1 1 1 1.98492146084213 -0.238604059029267 0.429958917577271 19.9556502272401 33.1490559410918 0.601997542937654 0.548055347114772 -93.4613649586414 106.119314248111 -0.88071964675653 0.379833142361563 CCDC71L other 1 1 1 0.601997542937654 -0.88071964675653 0.30901402405953 23.1593205762202 40.0330824452485 0.578504555773194 0.563820987144646 -71.2400994845631 84.7079023064892 -0.841008896983459 0.40172771480333 HOXA10 other 1 1 1 0.578504555773194 -0.841008896983459 0.00134996647470532 46.2184842797511 16.4783872819002 2.80479415182317 0.00569307766795161 -15.6575042099648 38.1001612902462 -0.410956376029126 0.681683308691163 TMEM200B other 1 1 1 2.80479415182317 -0.410956376029126 0.0447380540047016 329.670473083198 177.258509790964 1.85982875221037 0.064993380641425 -162.746128259994 307.259473820504 -0.529670008987477 0.597173753839799 PCDHGB6 other 1 1 1 1.85982875221037 -0.529670008987477 1.20514439860353e-10 12.1649616368286 2.24443788954583 5.42004824169595 2.38548189208611e-07 -4.44804987212277 3.78026613761428 -1.17664992627475 0.241237091428045 SERPINE3 other 1.42207039035216e-06 1 0.00271110017035586 5.42004824169595 -1.17664992627475 4.03697125957288e-08 139.509606217317 25.8229047187648 5.40255280096122 2.48597126513565e-07 -149.982851658176 118.584176407951 -1.26477963756487 0.207886054151263 C1orf210 other 0.000413466596405455 1 0.00282083159454942 5.40255280096122 -1.26477963756487 4.66917506101865e-06 8.71825166947275 1.73335070347955 5.02971017461824 1.42116453259607e-06 2.49778759425834 9.25366749444748 0.269924070186994 0.78759981754805 RAD21-AS1 other 0.0397860406949399 1 0.0153826849008199 5.02971017461824 0.269924070186994 0.147255305166883 97.0501472857355 110.753660649591 0.876270334691588 0.382256785762842 -210.402651143215 233.53702470704 -0.900939161176495 0.36903663473889 TRNP1 other 1 1 1 0.876270334691588 -0.900939161176495 0.397232795467133 -12.4735194992778 35.7405097303665 -0.349002283218132 0.727564315989307 -77.9346814315521 58.3983027787107 -1.33453675403669 0.183997825699484 LINC02159 other 1 1 1 -0.349002283218132 -1.33453675403669 0.0383943822572327 326.818326887401 167.92767337672 1.94618504690549 0.0536211216923893 -132.401783374734 292.982564059184 -0.451910112125267 0.652028145195876 PCDHGA5 other 1 1 1 1.94618504690549 -0.451910112125267 0.000410614954161295 16.2836724760261 13.4600148718106 1.20978116525926 0.228192941862207 -216.21342916564 55.8821740529378 -3.8690948022319 0.000160135802632553 NACA2 other 1 1 1 1.20978116525926 -3.8690948022319 0.0312224202889499 367.429954585593 174.353087435381 2.10739000949307 0.0368539410488917 -98.5812623522988 302.82964320381 -0.325533726848371 0.745259739565556 PCDHGA7 other 1 1 1 2.10739000949307 -0.325533726848371 0.563677894500093 65.0646050593922 85.6695255864949 0.759483662527123 0.448724287338456 -70.3000334098889 206.781462226228 -0.339972609986564 0.734340406799478 EIF5AL1 other 1 1 1 0.759483662527123 -0.339972609986564 7.77470834763327e-14 104.049872122762 13.9127116869782 7.47876290861035 6.27496525481488e-12 10.3190004262575 23.432928626649 0.440363242284716 0.660320891684712 ALG11 other 1.01763157562172e-09 1 8.40217847619712e-08 7.47876290861035 0.440363242284716 0.0330208217115874 44.1880107497395 18.7545171059615 2.35612628680764 0.0201589527019365 -37.2491818863233 78.3164316907283 -0.475624094231213 0.635244432034509 MINCR other 1 1 1 2.35612628680764 -0.475624094231213 5.05244567847943e-15 850.541957834391 144.136337048933 5.90095443833597 2.21923262441311e-08 -1030.45487041623 310.330570931121 -3.32050712027639 0.00112196338328155 ATXN7L3B other 6.77583489940876e-11 1 0.000266152568645864 5.90095443833597 -3.32050712027639 0.0420080922395955 328.212749294769 171.338220244888 1.91558397668463 0.057456897528806 -136.828890623293 298.276159970092 -0.458732238731426 0.647137823363675 PCDHGA6 other 1 1 1 1.91558397668463 -0.458732238731426 4.49764384935426e-08 79.3638466772511 16.6833763939241 4.75706144867381 4.62238203500284e-06 -143.207552733046 66.704535092206 -2.14689379867635 0.0334310200095227 OTUD6B-AS1 other 0.000459029531265096 1 0.0483454937040947 4.75706144867381 -2.14689379867635 0.0494803737089244 330.748196573491 171.727281922914 1.92600845287913 0.0561301309670038 -110.57178281592 298.334447982496 -0.370630289474342 0.711473099454019 PCDHGA8 other 1 1 1 1.92600845287913 -0.370630289474342 3.08344061504746e-13 265.502557544757 39.343755408639 6.7482769447692 3.21599608674091e-10 -34.5748614663257 66.2659755436373 -0.521758884294362 0.602623483746859 UTP14C other 3.97116316811963e-09 1 4.1209773855498e-06 6.7482769447692 -0.521758884294362 0.0336031608971235 338.323001631322 183.486340641608 1.84385933278895 0.0673027572582322 -221.451139806359 318.054780812923 -0.696267288422289 0.487407619579838 PCDHGA10 other 1 1 1 1.84385933278895 -0.696267288422289 0.0602088301719952 299.955954323002 174.395174428953 1.71997852179792 0.08763039124105 -172.249578928412 302.296175202341 -0.569804030147313 0.569717358885914 PCDHGA11 other 1 1 1 1.71997852179792 -0.569804030147313 0.0360809366126039 329.504362795963 172.001595770142 1.91570526610871 0.0574268235275784 -158.709626450334 300.090315894257 -0.528872869413949 0.597725201994114 PCDHGB2 other 1 1 1 1.91570526610871 -0.528872869413949 0.0443504347950768 352.151941150498 180.078241363524 1.95554964599865 0.05249548086545 -116.226830242631 312.773524019738 -0.371600603365957 0.710748059743516 PCDHGB4 other 1 1 1 1.95554964599865 -0.371600603365957 0.00336862152368865 9.7622053090774 14.2223024176928 0.686401190353892 0.493556319012741 -51.2549192500466 27.6579655797369 -1.85317025947844 0.0658904004541902 CLDN23 other 1 1 1 0.686401190353892 -1.85317025947844 3.68931240997833e-20 180.45638601839 19.3890712285259 9.30711862840014 1.58245013893224e-16 -137.582940800311 78.1554644635172 -1.76037519250538 0.080396028147137 ZNF260 other 5.21631881646837e-16 1 2.23046347082499e-12 9.30711862840014 -1.76037519250538 5.67718834651989e-07 39.3386530481964 13.6639219828713 2.87901622224645 0.00456484555889734 -35.1880759449359 26.1978113247043 -1.34316853834862 0.181219450405675 PINX1 other 0.00529038557427986 1 1 2.87901622224645 -1.34316853834862 2.24576010732675e-07 -4.70897997017298 4.18271283115141 -1.12581957219298 0.262016324842099 -38.3542479144212 7.98988922454722 -4.80034789425941 3.75574058732772e-06 RBPMS-AS1 other 0.00216828138362398 0.0546685599891423 1 -1.12581957219298 -4.80034789425941 0.0455544413777694 338.719412724307 178.307171159516 1.8996398771942 0.0595224815086827 -142.550708671427 309.077220910317 -0.461213894222214 0.645355825031668 PCDHGB7 other 1 1 1 1.8996398771942 -0.461213894222214 0.0132203225318482 3.08939383224448 34.036068995181 0.090768232743972 0.927797047193481 -192.633008208805 73.6257941620481 -2.61637935999476 0.00978973971933356 NPIPB11 other 1 1 1 0.090768232743972 -2.61637935999476 0.0317440309582764 360.5922554476 177.611675467045 2.0302283309889 0.044213673660561 -131.642659497531 309.878193622352 -0.424820662463147 0.671614978437995 PCDHGB1 other 1 1 1 2.0302283309889 -0.424820662463147 0.0486706690128494 321.905236927335 169.896038313124 1.89471891236247 0.0601770891797025 -118.912227882065 296.416760427629 -0.401165668602933 0.688905455374111 PCDHGA3 other 1 1 1 1.89471891236247 -0.401165668602933 0.210676444909301 40.1654482906902 32.2989624093415 1.24355227829466 0.215671175565899 -22.5570263878155 68.3429100447946 -0.330056568750595 0.741833585408499 HOXA-AS3 other 1 1 1 1.24355227829466 -0.330056568750595 0.00494104126621175 27.2406166219839 8.72187846639485 3.12325111235398 0.00226783326766277 -7.24486148346734 36.3220501849832 -0.199461799280885 0.84225686256156 RHPN1-AS1 other 1 1 1 3.12325111235398 -0.199461799280885 0.000794693710871098 63.0834260289212 19.9909402550685 3.15560074834033 0.00209516855840072 -91.9016499814606 74.0029636013067 -1.24186445392354 0.217079910468111 LRRC24 other 1 1 1 3.15560074834033 -1.24186445392354 0.0237183575160054 174.31135774573 114.811700853857 1.51823687350133 0.131242319545492 -157.067056556124 183.28602325615 -0.856950539739825 0.392957915090208 CHKB-CPT1B other 1 1 1 1.51823687350133 -0.856950539739825 0.411031157156632 13.0882930083154 9.81256930930752 1.33382935658868 0.184191511240856 15.8267783591949 19.0390851431783 0.83127830146112 0.407078898294504 SIGLEC14 other 1 1 1 1.33382935658868 0.83127830146112 0.00104865738708097 145.93015755525 94.7317330602054 1.54045696031451 0.125514677479002 -288.74498978757 150.508573027189 -1.91846207813962 0.056914712640109 SPON1-AS1 other 1 1 1 1.54045696031451 -1.91846207813962 0.00325227970134018 15.436790635313 5.16631825663439 2.98796742060744 0.00326313921848906 1.9102921162203 8.53869530335568 0.223721780477348 0.823266510104944 NAV2-AS2 other 1 1 1 2.98796742060744 0.223721780477348 0.0191295802434535 69.3682414849938 37.4723435263041 1.85118503293769 0.0660963363901266 -203.861403458047 123.924193228007 -1.64504926881359 0.102039782830821 AP5B1 other 1 1 1 1.85118503293769 -1.64504926881359 2.02315134603562e-07 70.9563492783467 34.2423035404052 2.0721838761408 0.0400442346390597 -353.88430869159 77.585957441794 -4.56119019936151 1.08450384408275e-05 CHMP4A other 0.00196447995700058 0.157437423045493 1 2.0721838761408 -4.56119019936151 0.000110964348156026 86.2001352265044 24.4671292255418 3.52309968333016 0.000560713322431508 10.4847870182556 38.0693798029136 0.275412603844235 0.783366070876401 PABPC4L other 0.810039741538993 1 1 3.52309968333016 0.275412603844235 0.00289005183352727 27.6413560492063 11.0191176944726 2.50849086248274 0.0131602322586498 -13.9297541805058 18.7500392318803 -0.742918668501844 0.45866270032973 BBOX1-AS1 other 1 1 1 2.50849086248274 -0.742918668501844 0.436782192351395 44.9184292564271 36.346865626056 1.23582676202557 0.218592558142178 55.9212391483651 57.2657962862982 0.976520764136221 0.330490815263086 MAGEL2 other 1 1 1 1.23582676202557 0.976520764136221 0.0082811913887237 196.202113141833 75.4137156942239 2.6016767816794 0.0101700603753825 22.8133586731747 116.768810306204 0.195372022831705 0.845355953297427 CSNK2A3 other 1 1 1 2.6016767816794 0.195372022831705 8.55946469856631e-05 21.6917767645093 8.70911423423863 2.49069838574757 0.0138316615235288 -40.769362456047 18.8789545364591 -2.15951377907675 0.0323889548971337 SMG1P6 other 0.63314360375295 1 1 2.49069838574757 -2.15951377907675 2.89745931247021e-07 77.6037952575017 18.3684734652767 4.22483639722168 4.05327221487969e-05 -128.070256321495 53.8083219514925 -2.38011987136393 0.0185146872227722 FPGT other 0.00276794288120279 1 0.386641636577374 4.22483639722168 -2.38011987136393 0.84044419735682 0.0243905788642436 1.1327582268167 0.02153202535795 0.982849130193613 1.75776511249972 3.13772210273839 0.560204203860393 0.576154176019109 SENCR other 1 1 1 0.02153202535795 0.560204203860393 0.822591697294686 126.029565605353 448.396506525058 0.281067233511797 0.779038571915428 1455.89572161305 2471.64219968518 0.589039838289898 0.556703242483279 IGLL5 other 1 1 1 0.281067233511797 0.589039838289898 0.000301209696073805 -18.2712003993015 50.7673850200955 -0.359900365009328 0.719452617076317 -250.058372847517 78.8854872554051 -3.16989070547173 0.00186570018681549 CKLF-CMTM1 other 1 1 1 -0.359900365009328 -3.16989070547173 5.93031124276054e-06 271.843622534345 61.3726105087881 4.42939644054116 1.77017952134377e-05 -236.542462172942 269.527792053013 -0.877618075565345 0.381500613683714 SYS1-DBNDD2 other 0.0500221753326852 1 0.175389386974741 4.42939644054116 -0.877618075565345 0.00476121290451072 -38.6878130217029 17.7039108355429 -2.18526931032844 0.0304103456622271 -97.8546767761084 29.3965859086271 -3.32877692260824 0.00109601453778861 SLC22A18AS other 1 1 1 -2.18526931032844 -3.32877692260824 0.0989361782309563 6.85297063839569 3.95540891813084 1.73255680518466 0.0851764771923678 0.666216419456382 6.26571616249709 0.106327258078488 0.91546108529786 GVINP1 other 1 1 1 1.73255680518466 0.106327258078488 0.00549633261409791 6.75840520552154 4.7252232985371 1.4302827143881 0.154648647610397 -18.7721395600618 10.8261481016363 -1.73396293712483 0.0849129581401203 NPIPA2 other 1 1 1 1.4302827143881 -1.73396293712483 5.2433480082824e-09 97.8646260477207 16.7044493804126 5.85859634274898 2.76265647931658e-08 -6.88449240134175 58.2876922194258 -0.11811228304296 0.906133611981143 MPV17L2 other 5.68588658018143e-05 1 0.000329805930500813 5.85859634274898 -0.11811228304296 0.00142022811996858 -6.68500749875948 5.27971042795772 -1.26616934583387 0.207352094963709 -29.0105651667289 8.30310141412076 -3.49394325322725 0.000620602278127354 TMEM9B-AS1 other 1 1 1 -1.26616934583387 -3.49394325322725 5.01576216863e-09 696.646410504153 133.337587272938 5.22468138768807 5.43930991409155e-07 -693.818208437584 437.517642901502 -1.58580624048979 0.114782638501542 ATP6V1G2-DDX39B other 5.44661613891532e-05 1 0.00604633690050417 5.22468138768807 -1.58580624048979 5.25787263133562e-07 100.752567274977 21.2217028381797 4.74761936133204 4.81347993265173e-06 -51.133340550572 71.5327104312727 -0.714824592026329 0.475843470021714 BORCS8 other 0.00491244487704881 1 0.0502479170169514 4.74761936133204 -0.714824592026329 3.67635916167855e-07 85.5663697580525 22.2831254570534 3.8399626624625 0.000181474480105859 -93.7276066071377 55.3096938075008 -1.69459637461285 0.0922410595426306 INMT-MINDY4 other 0.00348077685427725 1 1 3.8399626624625 -1.69459637461285 0.000658494383838623 264.532647777937 85.2983093848291 3.10126483966382 0.0023025510403828 -513.067050194162 279.245906462794 -1.83733060474611 0.0681399213729235 DPP3 other 1 1 1 3.10126483966382 -1.83733060474611 0.000728514696319229 175.599191224944 45.2430039671216 3.88124518328964 0.000156048922341971 146.049975686777 183.82439433499 0.794508129430443 0.428171852831238 STX16-NPEPL1 other 1 1 1 3.88124518328964 0.794508129430443 4.60954188998785e-07 805.815136609014 180.399171518524 4.46684499616046 1.56626130012065e-05 -258.681040540672 264.819854227788 -0.976818906931972 0.330252768856728 ANKHD1-EIF4EBP3 other 0.00433020365145458 1 0.155936975040012 4.46684499616046 -0.976818906931972 0.000121194804178596 97.2510964912288 159.502209093091 0.609716298251828 0.54293117087754 -1128.61354775828 327.524658014565 -3.44588879078562 0.000730351015827293 BRK1 other 0.880237862749144 1 1 0.609716298251828 -3.44588879078562 0.264839792164519 -0.670729282968444 6.65161269063524 -0.100837092320898 0.919809263107296 -62.3679366532364 38.5332100625699 -1.61855024670833 0.107564106243456 SAA2-SAA4 other 1 1 1 -0.100837092320898 -1.61855024670833 4.85312420001494e-10 42.4085648148148 18.8393790110527 2.25105959118581 0.0257787871320463 -98.8557098765431 28.1807633696358 -3.50791455078389 0.000590220490049084 PIGY other 5.56798939467715e-06 1 1 2.25105959118581 -3.50791455078389 2.49975618997024e-16 409.383474015011 76.4136351036338 5.3574662880492 3.16459904003055e-07 -827.947687193205 204.810527295881 -4.04250552022214 8.47541187249188e-05 CHMP1B other 3.42191624845027e-12 1 0.00356808541763445 5.3574662880492 -4.04250552022214 0.00155430908529118 2.5558811519708 2.30338590853192 1.10961916650771 0.268870733779897 -8.30100321059414 3.44312485688226 -2.4108923015097 0.0170761472387561 STX17-AS1 other 1 1 1 1.10961916650771 -2.4108923015097 7.75919192879786e-05 4.34576258607619 3.59730488000674 1.20806068182579 0.228875799424871 -20.8833834284876 7.16678729426764 -2.91391143214076 0.00410133335166807 EID3 other 0.577439063341137 1 1 1.20806068182579 -2.91391143214076 2.77611574239478e-05 71.7431129851879 18.7558552426974 3.82510485695505 0.000189492428528497 -82.0951713953931 65.9651858629678 -1.24452270271674 0.21519794530644 MSH5-SAPCD1 other 0.218813442815556 1 1 3.82510485695505 -1.24452270271674 0.0784599892330676 12.5076293055088 5.50970061504975 2.27011051586799 0.0246064756570851 11.1388421406934 9.52475653421774 1.16946213802705 0.244048075536104 TOLLIP-AS1 other 1 1 1 2.27011051586799 1.16946213802705 2.45500076566699e-13 44.432119295994 13.9171888668624 3.19260733766353 0.00171807073890311 -165.896703786888 32.7816533037746 -5.06065701597138 1.20631690517913e-06 HTD2 other 3.17161548916518e-09 0.0175977510127532 1 3.19260733766353 -5.06065701597138 0.00798982208779654 42.4581962030447 18.3135926537397 2.31839797934866 0.0217786000747645 1.94769053679405 29.7654214679908 0.0654346701889829 0.947915048131757 PDXDC2P other 1 1 1 2.31839797934866 0.0654346701889829 0.109626460859796 26.6971369615682 17.1671578025738 1.55512853487988 0.122222558081095 -13.4260338749891 36.2969416518617 -0.369894356493269 0.712032386952932 SNHG9 other 1 1 1 1.55512853487988 -0.369894356493269 0.00414654002084755 9.69073507758524 3.2186695081433 3.01078910185326 0.00307798804140473 -6.32699059916184 10.2170341377478 -0.61925902506151 0.536724240073915 PGAM1P8 other 1 1 1 3.01078910185326 -0.61925902506151 0.0147661172361621 65.679536334991 26.2816725156084 2.49906227603988 0.0135012121333721 -37.6130360395845 73.2333271740507 -0.513605451110955 0.608263970411894 FXYD6-FXYD2 other 1 1 1 2.49906227603988 -0.513605451110955 0.0247412505739558 43.8939504009595 96.7459583996988 0.453703194707265 0.650681175625003 -654.061008870722 270.542941599681 -2.41758666850946 0.0167917963608172 MIR100HG other 1 1 1 0.453703194707265 -2.41758666850946 0.230850432666567 3.72529713072373 3.6476110156469 1.02129780690528 0.30870474179892 -7.21463903098156 10.1640414426221 -0.709819914815338 0.478882296900076 WTAPP1 other 1 1 1 1.02129780690528 -0.709819914815338 0.00014070792715074 449.667097059999 145.511291967078 3.09025568381136 0.00238425381361931 -258.679403788182 219.455856998261 -1.17873091803712 0.240371755605209 EID1 other 1 1 1 3.09025568381136 -1.17873091803712 0.671528309885616 -0.133776884198072 2.97909258181494 -0.0449052456491876 0.964242165603142 -4.13865537212403 5.78824342853354 -0.715010594012382 0.475706521422286 SOGA3 other 1 1 1 -0.0449052456491876 -0.715010594012382 0.0775930006425816 24.6360757262705 10.9309476689477 2.25379138866943 0.0256205798600225 10.0707262975798 18.7999328595073 0.535678843793683 0.59295331811605 NOX5 other 1 1 1 2.25379138866943 0.535678843793683 0.0714311318612454 18.6317838687395 64.6873088725355 0.288028427731519 0.773744944397977 -199.859327745101 103.298179334571 -1.93478073894972 0.0550052499700587 PCDHA3 other 1 1 1 0.288028427731519 -1.93478073894972 0.000275410741137146 7.94427493958849 3.02344983902759 2.6275530809347 0.0094701561275236 -10.4492243581067 7.20717574598947 -1.44983620857606 0.149137698628832 EBLN2 other 1 1 1 2.6275530809347 -1.44983620857606 0.0180711016799213 3.24798387096773 2.59933922936752 1.24954212758065 0.213400197593971 -9.28369656980361 5.50058914862092 -1.68776404108116 0.0935209691558164 NPIPB8 other 1 1 1 1.24954212758065 -1.68776404108116 1.32612532055388e-10 198.662544362214 62.3700104250997 3.18522544742537 0.00177830832146921 -591.999182402888 129.443833771279 -4.57340581745224 1.03585758351547e-05 NEDD8-MDP1 other 1.5617777900163e-06 0.150416879702281 1 3.18522544742537 -4.57340581745224 5.34339459849085e-05 217.553211982142 70.1319408154394 3.10205605965845 0.00228657477913981 -191.562659424263 111.826361921444 -1.71303667697633 0.0887182334711665 POLR2M other 0.40561708397144 1 1 3.10205605965845 -1.71303667697633 0.975532908057123 0.691318879081306 5.67491364677752 0.121820158351461 0.903288381164678 -2.92418659125321 20.8545391151756 -0.140218231393343 0.888772454767368 ZNF252P-AS1 other 1 1 1 0.121820158351461 -0.140218231393343 2.38105472812551e-14 40.7298019849983 5.76540802658596 7.06451335225216 5.52736110539114e-11 -14.7248897030813 14.8253833970446 -0.993221511291011 0.322190947915118 FDXACB1 other 3.15418319834786e-10 1 7.25134503416264e-07 7.06451335225216 -0.993221511291011 0.457905784396674 4.05547836443033 3.35734267844665 1.2079429336974 0.228982986314877 5.76757903094378 7.95434930721955 0.725084957698425 0.46953709731058 PCDHB17P other 1 1 1 1.2079429336974 0.725084957698425 0.0829953127876672 315.951193377053 155.045633598229 2.03779484816567 0.0433161161126396 109.613835755462 337.872254999728 0.324423903216173 0.746066107066976 TRIL other 1 1 1 2.03779484816567 0.324423903216173 0.0136045637083272 43.2604590339488 14.5321647553214 2.97687645043438 0.00345236152415633 34.8271363407024 49.5005394819842 0.70357084397793 0.482911769347187 AGAP2-AS1 other 1 1 1 2.97687645043438 0.70357084397793 0.222937577424311 15.9231984205332 27.1409571195868 0.58668522080387 0.558279775907422 -57.4288632394257 54.0744979010419 -1.06203229745235 0.289894500841663 RMST other 1 1 1 0.58668522080387 -1.06203229745235 0.362716982964272 -3.97293258943297 3.52608510793542 -1.12672623258353 0.261588436815481 7.49419661861762 15.4232885031588 0.485901344391163 0.627718921487547 KLRC4 other 1 1 1 -1.12672623258353 0.485901344391163 0.218836398045826 -2.19901821266496 3.132550658696 -0.701989673035438 0.483738378598388 5.3396390842214 5.15650111857516 1.03551593637525 0.302040876098561 TIFAB other 1 1 1 -0.701989673035438 1.03551593637525 1.29507799593841e-09 3.09212429157708 0.847664367164884 3.64781676728853 0.000362845591907819 -10.2345264803596 2.38015138135868 -4.29994770942567 3.04126166965125e-05 TMEM5-AS1 other 1.45359554264127e-05 0.439036534630855 1 3.64781676728853 -4.29994770942567 3.55340180500051e-08 155.143477941665 41.3594033177323 3.75110532301005 0.000248258667300951 -179.885965801627 80.9346218226982 -2.22260834424727 0.0276897608401581 PXN-AS1 other 0.000365218637517952 1 1 3.75110532301005 -2.22260834424727 0.66338063139168 -0.0810968862694268 0.919817415310579 -0.088166287047353 0.92986369759065 -6.27137443312445 6.91759817183573 -0.906582642897312 0.366101187356448 DENND5B-AS1 other 1 1 1 -0.088166287047353 -0.906582642897312 0.000178584457784946 42.006733888165 9.90687634580651 4.2401593016699 3.85040439189317e-05 20.1435460709856 18.0547779689047 1.11569060033185 0.266303846960418 LINC00346 other 1 1 0.368264705561977 4.2401593016699 1.11569060033185 0.185325718231557 -28.3248712288447 24.232597499604 -1.16887474523965 0.244272025082802 -69.6712043168996 37.8984649036318 -1.83836481224397 0.0679477585634885 MT1JP other 1 1 1 -1.16887474523965 -1.83836481224397 8.60283491484409e-09 114.197105232285 65.2757904887147 1.74945572282312 0.0821662648122333 -369.365239324262 102.897057062474 -3.5896579539685 0.000442169363703297 CTSO other 9.2093347763406e-05 1 1 1.74945572282312 -3.5896579539685 1.37467812125302e-12 158.325474208498 32.0212074026477 4.94439426401538 2.04681775070704e-06 -240.5648162384 63.0184037664208 -3.81737400283985 0.000197755218874302 APOPT1 other 1.73869288776082e-08 1 0.0219418862875795 4.94439426401538 -3.81737400283985 0.000219281966845276 19.8291344250495 9.54959249404132 2.07643775767629 0.0394936168960731 -36.4923459900425 18.9587308752793 -1.92483063503083 0.0560703259343755 TRAPPC2B other 1 1 1 2.07643775767629 -1.92483063503083 0.00175020818645387 41.5623952793763 19.8972305593655 2.0888532781168 0.0383767519985667 -53.3220999975717 29.7272540869335 -1.79371091058858 0.0748342730800383 DNAAF4 other 1 1 1 2.0888532781168 -1.79371091058858 0.0490626818138975 21.4427846220516 14.1649137461585 1.51379563662128 0.132210303570466 -32.0341422645948 28.0226010712374 -1.14315377730852 0.25482052833252 URB1-AS1 other 1 1 1 1.51379563662128 -1.14315377730852 1.41618330926231e-07 53.3913546057778 14.5441217630186 3.67099199771115 0.000331310826154574 -49.974423550206 28.2052265597854 -1.77181429279702 0.078377650972219 ZNF432 other 0.00139253304799763 1 1 3.67099199771115 -1.77181429279702 0.135328116277057 7.83712633115305 5.05447045978902 1.55053361049422 0.123026956603851 -25.3933658576138 20.2298286405198 -1.25524374471228 0.211255412458538 LINC01152 other 1 1 1 1.55053361049422 -1.25524374471228 0.00078780848805772 14.7113948289936 3.97604282853067 3.70000914563341 0.000298953879937547 3.93783806464901 18.2280553531691 0.216031715306613 0.829247063793366 CCND2-AS1 other 1 1 1 3.70000914563341 0.216031715306613 1.19949623088381e-11 83.6928467501294 14.0696307254295 5.94847500857737 1.91652466423032e-08 -23.3532934377851 26.8779230324655 -0.868865254565129 0.386346894910255 ZNF10 other 1.47070232868664e-07 1 0.000230519586613623 5.94847500857737 -0.868865254565129 0.0954606018653785 38.6646895176107 44.9594768985762 0.859989754881581 0.391122884516742 -214.51796231169 151.162798455274 -1.41911875477193 0.157872213803315 ZNF486 other 1 1 1 0.859989754881581 -1.41911875477193 0.297634165998967 -28.1633107098229 62.7144360433711 -0.449072215053422 0.654006811895293 115.240928135643 99.1602300350055 1.16216882610055 0.246953232091311 SMIM3 other 1 1 1 -0.449072215053422 1.16216882610055 1.37569596746266e-07 112.648701222068 24.5130664766894 4.59545529847076 9.59610628707954e-06 -144.310026004045 69.8409585958846 -2.06626639876258 0.0406597672896728 HMBS other 0.00135368483198325 1 0.0975924009395989 4.59545529847076 -2.06626639876258 1.12173734523672e-19 14.4504543455152 1.729686425817 8.35437807097874 3.36968465956176e-14 -27.8539368873166 7.57134111447655 -3.67886434730292 0.000322046907812949 ZNF225 other 1.58209835172187e-15 1 4.65521935718457e-10 8.35437807097874 -3.67886434730292 0.0526026484210229 5.95056228734598 2.5896389696105 2.29783470096644 0.0228998636946469 10.220886680326 5.24787359247025 1.94762440448091 0.0532553368786643 ABCC6P1 other 1 1 1 2.29783470096644 1.94762440448091 3.37116337449387e-05 35.466650509989 14.7324756623968 2.40737886304568 0.0173249507012159 -50.609995363736 21.8813634993884 -2.31292695106274 0.0221332506559864 DND1 other 0.262647338506817 1 1 2.40737886304568 -2.31292695106274 4.30961408641575e-12 73.2610862988041 9.26827809220224 7.90449807073026 5.08229929339965e-13 7.869961100706 36.5752244779541 0.215171915225009 0.829921724051778 POLG2 essential 5.36417665336169e-08 1 6.93276446612646e-09 7.90449807073026 0.215171915225009 1.02284805300611e-14 162.950775226325 21.2877094197887 7.65468806497557 1.89249741802058e-12 -170.97939031329 98.5782506481611 -1.73445348430394 0.0848129303904186 SMIM10L1 other 1.36407016348895e-10 1 2.55903500864742e-08 7.65468806497557 -1.73445348430394 0.868132940616841 -3.37869222096955 6.36053388210117 -0.531196324647737 0.596033438308987 -4.60894605582316 19.412093979017 -0.237426527030267 0.812635456233505 CYP2B7P other 1 1 1 -0.531196324647737 -0.237426527030267 0.249632641633193 99.5506187680122 65.3080647991278 1.52432351309454 0.129439739786391 198.411322761108 159.127873666316 1.24686717788467 0.214303155754759 MTRNR2L1 other 1 1 1 1.52432351309454 1.24686717788467 9.95867883480832e-14 36.6342292746115 4.53574186150018 8.07678884584821 1.79248132941268e-13 -21.9995142487047 20.09601726287 -1.09472011100188 0.275348489482811 ZBTB11-AS1 other 1.29930882757744e-09 1 2.45749190262478e-09 8.07678884584821 -1.09472011100188 1.61378459573312e-06 33.5350837928372 11.0075295450313 3.04655859933392 0.00271879913002042 -42.0641731308729 21.3467591745946 -1.97051799698638 0.050548943609675 ZNF350 other 0.0144482134855986 1 1 3.04655859933392 -1.97051799698638 0.53941590612441 15.9852072179259 35.1291897354226 0.455040589843356 0.649737956419689 -93.2592107872299 113.736780442306 -0.819956485708127 0.413541932901455 PGA5 other 1 1 1 0.455040589843356 -0.819956485708127 2.10598678995527e-05 6.49224828877318 1.51409243949973 4.28788105627042 3.18126531640407e-05 -3.15515123149828 5.71742537423892 -0.551848257734064 0.581857461522818 PLBD1-AS1 other 0.168141985310029 1 0.307596543443109 4.28788105627042 -0.551848257734064 2.10607730431619e-11 84.4550602263946 13.8190488362306 6.1114958943463 7.75651104147913e-09 -63.3415738253091 46.6421591378443 -1.35803262533606 0.176439657840052 ZNF253 other 2.55951574793546e-07 1 9.48543735262483e-05 6.1114958943463 -1.35803262533606 0.0397981569143281 -1954.83988683962 1675.27857828445 -1.16687451996279 0.245053130331127 -6518.57198622777 2654.04215140356 -2.4560921094567 0.0151498004800945 HP other 1 1 1 -1.16687451996279 -2.4560921094567 0.0653567449422154 11.1001967610111 5.84982031078777 1.89752781645976 0.0597740611296822 -19.2313293260395 25.3181318076945 -0.759587218840326 0.448751742952396 MIR200CHG other 1 1 1 1.89752781645976 -0.759587218840326 2.45558554695381e-08 365.495330574807 58.4401779571225 6.25417894591237 3.7598209566431e-09 206.741599518326 200.719960997722 1.03000019774153 0.304624874885395 KIAA1147 other 0.000255282673461318 1 4.65353039803716e-05 6.25417894591237 1.03000019774153 1.0477906983983e-20 694.010444614796 71.8996030248012 9.65249341328633 1.7235478809257e-17 -416.60694537823 272.65055474823 -1.52798862178341 0.128593662343395 LSM14A other 1.48608154753831e-16 1 2.44278441163599e-13 9.65249341328633 -1.52798862178341 0.00544898727754641 3.88428410303618 7.06532683958242 0.549767079602754 0.583415209168705 -35.7090184455559 15.1674765193907 -2.3543150635443 0.0200431243542948 NHLRC4 other 1 1 1 0.549767079602754 -2.3543150635443 1.62706367517602e-05 60.0625157680863 27.9880190831221 2.14600810402857 0.0334597574941851 -139.949257094435 55.8321507458094 -2.50660695002761 0.0132416146620985 TMPO-AS1 other 0.131434203680719 1 1 2.14600810402857 -2.50660695002761 0.516653281661192 -6.29185575038266 5.643049365726 -1.11497443006565 0.266609660445684 -7.2907011089934 22.9831070576658 -0.317219995133846 0.751509145117653 MIR10A other 1 1 1 -1.11497443006565 -0.317219995133846 2.97643984863008e-11 209.840485047208 97.5087505050461 2.15201696217355 0.0329441730869167 -994.088496948045 196.602914291599 -5.05632635472344 1.19256522625563e-06 GATC other 3.59792048902404e-07 0.0173983340858434 1 2.15201696217355 -5.05632635472344 1.14243015823921e-23 243.976086315932 23.9974912192364 10.1667330175065 8.51101873927991e-19 4.54532266473217 61.2008958761029 0.0742688909968551 0.940895381109978 ZNF271P other 1.63904454802579e-19 1 1.21341594165914e-14 10.1667330175065 0.0742688909968551 7.48644483755294e-07 128.158897066125 24.0105973183097 5.33759720206524 3.41593929534013e-07 -34.897353002835 83.5096559647602 -0.417884047056321 0.676629487716885 ZBED6 other 0.00689576433987002 1 0.00384361489511672 5.33759720206524 -0.417884047056321 0.0539791545459836 6.22044758135161 2.65145173853665 2.3460534811713 0.0202476521591271 12.0549673854618 10.4841422083375 1.14982867896193 0.251996930585594 MGAM other 1 1 1 2.3460534811713 1.14982867896193 1.21519077409681e-08 184.267777777778 40.9753745329789 4.49703705891621 1.36534055886879e-05 -92.4940476190474 59.8285960098216 -1.54598392387251 0.12420170027742 FNTB other 0.000128931741131671 1 0.136711550159532 4.49703705891621 -1.54598392387251 0.156139260671122 -9.50845282891264 7.41774052461284 -1.28185298439095 0.201820708107177 -37.3704892101739 20.6278992966582 -1.81164784027368 0.0719890694521885 OR7E47P other 1 1 1 -1.28185298439095 -1.81164784027368 0.808948000350403 -0.417282338983167 1.54131722672562 -0.27073099018665 0.786958117510718 -3.08119525007786 4.7350293704396 -0.650723577199649 0.516188390709239 HLX-AS1 other 1 1 1 -0.27073099018665 -0.650723577199649 8.59338535128352e-20 41.8639278070036 4.48509002003007 9.33402175208134 1.28672798454328e-16 -23.7593788455077 19.2940049589206 -1.23143841292124 0.220086101075575 ZNF625 other 1.2125266730661e-15 1 1.81480114939984e-12 9.33402175208134 -1.23143841292124 0.0647219693437788 6.33155883278638 99.678962192505 0.0635195099700031 0.94943795829189 -399.770035070365 208.257703663681 -1.91959302363173 0.0568204579713269 GALNT4 other 1 1 1 0.0635195099700031 -1.91959302363173 0.00245484290550652 111.106533000767 37.0038004937985 3.0025708580768 0.00311587575618394 -8.60428178562281 51.8967768851912 -0.16579607255105 0.86853074501439 PSMA3-AS1 other 1 1 1 3.0025708580768 -0.16579607255105 0.830933340024812 103.268809529669 174.723639724034 0.59104085567801 0.555359529521859 165.572957745411 483.30220208528 0.342586806000514 0.732376472597104 KRT7-AS other 1 1 1 0.59104085567801 0.342586806000514 0.0508301809798444 12.0751985423386 23.9928642295726 0.503282910568687 0.615470741387803 -76.9742231757348 46.2155092925534 -1.66554960345611 0.0977972943493016 INAFM1 other 1 1 1 0.503282910568687 -1.66554960345611 1.2134700161234e-09 340.260507997996 86.0101604355999 3.956050148898 0.000122927137443452 -895.33012080725 232.630301197353 -3.84872527868884 0.000183020662171033 CNPY2 other 1.36418299212593e-05 1 1 3.956050148898 -3.84872527868884 8.54962673814281e-17 22.0449391441904 2.42566802998452 9.08819297269259 4.3260035797312e-16 -17.7130620123401 13.1003947453578 -1.35210139515962 0.178299833404231 LINC01481 other 1.17736909810965e-12 1 6.08106323202815e-12 9.08819297269259 -1.35210139515962 0.00138935078081478 421.318722392117 117.171703826828 3.59573778166441 0.000435876764945104 76.2782874617732 373.166715062816 0.204408068519544 0.838306283335586 CUX1 other 1 1 1 3.59573778166441 0.204408068519544 2.65835388534441e-07 124.467441361974 21.5313882128536 5.78074391356106 3.93041866882961e-08 -14.1362104018763 100.133270268066 -0.141173961102362 0.887914652566741 TEN1 essential 0.00254909554065675 1 0.000466108349936504 5.78074391356106 -0.141173961102362 1.27432185383733e-17 1090.94741859783 112.957265885468 9.65805439823577 1.36779095791376e-17 -696.128263420358 636.694747236369 -1.09334695541618 0.275926944258802 P2RX5-TAX1BP3 other 1.77003305498005e-13 1 1.93925402013013e-13 9.65805439823577 -1.09334695541618 5.46963350808759e-07 16.9313356326931 4.94382440519482 3.42474453884369 0.00079257373227844 -34.7911590671772 12.5870030112075 -2.7640542419986 0.00642001004281917 BCDIN3D-AS1 other 0.00510262109969491 1 1 3.42474453884369 -2.7640542419986 0.566466096912682 -2.94804770181207 11.4748408645054 -0.256914037991683 0.797585848939946 -22.9871143157062 22.3841637969973 -1.02693647724244 0.306050310235874 MAP1LC3B2 other 1 1 1 -0.256914037991683 -1.02693647724244 0.182896417524015 -9.02845892671885 11.069296360332 -0.815630789240883 0.415962929265129 55.8386777327171 39.5190767431032 1.41295501652786 0.1596738646039 CLEC5A other 1 1 1 -0.815630789240883 1.41295501652786 1.17535787751443e-05 -7.94960659423004 74.4820545602582 -0.106731838174504 0.915144337155413 -465.090898142697 108.955602854125 -4.26862764244794 3.4723671091519e-05 CHURC1 other 0.0964446355950437 0.500854231824069 1 -0.106731838174504 -4.26862764244794 0.003247238012695 68.060696473103 19.8484602723776 3.42901643447984 0.000776224291777322 37.1796917480735 31.5305555795155 1.17916386390058 0.240139758384238 VASH1-AS1 other 1 1 1 3.42901643447984 1.17916386390058 3.40682018982738e-10 414.622397463178 60.8800719477746 6.81047811209649 2.01886919458495e-10 -96.423603287856 327.830626392273 -0.294126282065172 0.769054916445992 C17orf49 other 3.93998754953536e-06 1 2.60757145172592e-06 6.81047811209649 -0.294126282065172 1.77274138264064e-19 16.7309441607353 1.7111125025652 9.7778165583229 1.0543368085883e-17 -6.73674378734202 7.6881819725066 -0.876246661620787 0.382325592318921 ITFG2-AS1 other 2.49743805986414e-15 1 1.49568219666337e-13 9.7778165583229 -0.876246661620787 0.000344350393326835 100.544867392959 33.2706295090781 3.02203080844996 0.00309023148346235 -134.893218388671 114.181352285679 -1.18139447193769 0.239862452671078 RTEL1 other 1 1 1 3.02203080844996 -1.18139447193769 3.23709906564465e-16 315.507533227772 50.603423203083 6.23490493837875 4.09755656357222e-09 -560.033539657405 154.772899267311 -3.61842119846939 0.000400668930040797 PPT2-EGFL8 other 4.42446700292311e-12 1 5.06539942388798e-05 6.23490493837875 -3.61842119846939 0.356953616233543 6.32357886384676 6.39886639797214 0.988234238778725 0.3245981998828 14.1294041524191 10.2990658429986 1.37191123620443 0.172099333260538 MEG8 other 1 1 1 0.988234238778725 1.37191123620443 0.06883673858756 5.2470723059843 2.32920160597871 2.25273428135884 0.025688750324474 3.49615012713533 6.49421885280631 0.53834806100268 0.591114031105633 ZNF578 other 1 1 1 2.25273428135884 0.53834806100268 1.2685401428053e-09 114.680418945768 24.0481863602676 4.76877620739179 4.3272044562591e-06 -8.69121963583431 38.7450298448836 -0.224318310519562 0.82281286941197 PDF other 1.42457058037035e-05 1 0.0453577571105079 4.76877620739179 -0.224318310519562 0.00148504520048764 35.7574734324967 9.74384494216238 3.66974984154062 0.000336099828262191 28.2214691085384 29.0739512805099 0.970678833305228 0.333260517959931 LINC00641 other 1 1 1 3.66974984154062 0.970678833305228 0.403202913138809 15.6028206562576 16.6850688481634 0.93513672603006 0.351181874995747 -15.6485755482815 28.1672186499941 -0.555559842195663 0.579317963851619 SPESP1 other 1 1 1 0.93513672603006 -0.555559842195663 0.883350602431487 -1.49118415193347 4.11712575808256 -0.362190576521993 0.717712682176736 -3.10063907376428 6.66415022419298 -0.465271485403792 0.642402950786085 MIR1247 other 1 1 1 -0.362190576521993 -0.465271485403792 3.08068252403993e-82 653.693573520227 16.1262391711852 40.5360212372555 2.17451074374974e-83 478.078442847175 88.9044859936732 5.37743891665036 2.79531383852673e-07 SPECC1L-ADORA2A other 4.505190123156e-78 0.004083114923936 3.18000451165962e-79 40.5360212372555 5.37743891665036 0.000680160810637288 9.66470339854706 3.67449428039814 2.63021321059176 0.00938270420725727 -10.2819058136555 6.43037616697204 -1.59895868401383 0.111840320576082 FAM181A-AS1 other 1 1 1 2.63021321059176 -1.59895868401383 5.21712889640488e-08 7.91170069600692 13.2723563615583 0.596103697073879 0.55196990563362 -92.1268845806085 21.1949816164669 -4.34663668257362 2.4832024308659e-05 TRIM6-TRIM34 other 0.000530112467163699 0.359145567576135 1 0.596103697073879 -4.34663668257362 7.3585032675098e-05 138.830300729784 85.5986434286665 1.62187501073517 0.107002521001956 -706.487600202447 202.086224773148 -3.49597109350483 0.000627071694102179 BCL2L2-PABPN1 other 0.549385853952282 1 1 1.62187501073517 -3.49597109350483 1.06292611242448e-06 91.2699012641446 76.8371317819449 1.18783586981303 0.236715076460524 -448.24458348355 111.945637396167 -4.00412730598198 9.62860935266771e-05 SYNJ2BP-COX16 other 0.00968113103196216 1 1 1.18783586981303 -4.00412730598198 0.0233115340651013 15.1374071981924 8.01550555356497 1.88851558981952 0.0608746323838317 -22.7006334732085 15.8132368707382 -1.43554628687155 0.153199720086139 LINC00930 other 1 1 1 1.88851558981952 -1.43554628687155 2.38112587014434e-08 -0.412347288516933 11.098966797283 -0.0371518625155159 0.970411419201074 -86.6910654582921 17.7242375673048 -4.89110265697451 2.47405919410474e-06 TRIM34 other 0.000247803769305921 0.0360495165173002 1 -0.0371518625155159 -4.89110265697451 0.739827554566328 0.428866496795615 4.02554269943849 0.106536317911976 0.915294603063002 -4.0356150104239 6.23096545587571 -0.647670900922485 0.518155989596139 LINC02308 other 1 1 1 0.106536317911976 -0.647670900922485 0.0202265855890278 8.43532109599431 3.51727127025832 2.39825718514307 0.0177723120011115 -1.73009405173738 5.3305186690896 -0.324563923163759 0.745988769547007 LINC00871 other 1 1 1 2.39825718514307 -0.324563923163759 2.94700533300676e-14 74.3611211375903 8.63958472181075 8.60702493603247 1.18165263498895e-14 33.534774907873 17.6733575488869 1.8974761765053 0.059766903697879 LINC00638 other 3.89387814650183e-10 1 1.64178817105364e-10 8.60702493603247 1.8974761765053 0.000905728207712092 7.0059702906963 4.7821770959951 1.46501690549343 0.145023198112342 -18.4662828622648 7.2444541630993 -2.54902335586932 0.0118137541552822 SLC25A21-AS1 other 1 1 1 1.46501690549343 -2.54902335586932 0.000419787390396536 52.0127456435484 14.1753992614443 3.66922614906644 0.000340291452418101 -9.82948259932783 28.0012068717668 -0.351037819346235 0.726066006866264 PRC1-AS1 other 1 1 1 3.66922614906644 -0.351037819346235 0.00130483802498809 13.1255823844414 3.791039014466 3.46226518227754 0.000692456194066469 3.0410778381374 5.38498653285647 0.564732672882704 0.573071990437546 HIF1A-AS1 other 1 1 1 3.46226518227754 0.564732672882704 1.41066523778019e-06 57.4506659120705 13.3145513749589 4.31487808294615 2.87413548315167e-05 -73.3091677734393 40.1317575056846 -1.82671211852746 0.0697178572837834 RNASE4 other 0.0126973978052595 1 0.278963589994701 4.31487808294615 -1.82671211852746 0.000776585245238446 37.1496252553334 23.2139264968817 1.6003163127239 0.111866053950562 -75.2365038165592 41.040457958719 -1.83322768698723 0.0689715837282559 MC1R other 1 1 1 1.6003163127239 -1.83322768698723 1.04244214891559e-11 232.357408951904 30.014657069752 7.74146472544803 1.24746558761032e-12 17.1906658326369 120.144154798398 0.143083663632933 0.886412372606338 CEP95 other 1.28074442415769e-07 1 1.69118909712331e-08 7.74146472544803 0.143083663632933 0.0462801559833072 18.9956372888182 8.45545051431481 2.24655531442816 0.0260903957801645 -0.630523425645477 14.6642460429682 -0.0429973299546366 0.965759361044514 FOXN3-AS1 other 1 1 1 2.24655531442816 -0.0429973299546366 4.1409440826121e-05 681.956013576815 173.252115048792 3.93620599312603 0.000131961924002089 126.289060220239 306.296573519098 0.412309738791003 0.680766406611337 TUBB3 other 0.318107324426261 1 1 3.93620599312603 0.412309738791003 0.00768990465616301 49.8793943843347 49.8062125155858 1.00146933213856 0.318291578050161 -242.777548773003 115.050405436187 -2.11018420884802 0.0365836723489411 UBE2F-SCLY other 1 1 1 1.00146933213856 -2.11018420884802 7.17502977827817e-08 63.2469340479652 11.0464105136019 5.72556433332681 5.09880114668494e-08 -46.3559002543615 45.4526382803166 -1.0198725972401 0.309357880567002 TVP23C-CDRT4 other 0.00072274074956596 1 0.000601505571274422 5.72556433332681 -1.0198725972401 0.00330624281710911 11.1197472158114 4.93316922993904 2.25407779411386 0.0255839090994686 -25.4842939235762 14.5757371093614 -1.74840515662215 0.0823610458529075 FPGT-TNNI3K other 1 1 1 2.25407779411386 -1.74840515662215 0.000343298072741758 816.030534377286 226.44107714322 3.60372130654175 0.000421400140496464 -71.9542789108573 618.979735225178 -0.116246582587524 0.90760663159845 BLOC1S5-TXNDC5 other 1 1 1 3.60372130654175 -0.116246582587524 0.216073599506532 7.38444356640031 9.22940650921984 0.800099503583846 0.424944249930773 -14.828074476063 14.014303630775 -1.05806716243117 0.291760414287135 LINC00639 other 1 1 1 0.800099503583846 -1.05806716243117 0.0566957121504602 5.06187671417672 98.435102420434 0.0514234921253653 0.959056940251842 -406.024351423047 205.658926809335 -1.97426077108469 0.0502009124007745 POC1B-GALNT4 other 1 1 1 0.0514234921253653 -1.97426077108469 0.00376154880890401 683.789302846639 205.02980573873 3.33507267581374 0.00107795991640893 86.7807284635057 762.494415220947 0.113811625018079 0.909541367048748 NDUFC2-KCTD14 other 1 1 1 3.33507267581374 0.113811625018079 2.2205526394254e-07 11.4359109056524 9.39383400316819 1.21738481878597 0.22530799970899 -248.921306997268 43.5990841467624 -5.70932421789765 5.61850212346419e-08 SMIM6 other 0.00214505384968493 0.000821312640407995 1 1.21738481878597 -5.70932421789765 0.00858506529658891 6.97471748779997 2.42022284876079 2.88184928564376 0.00463777800685042 -0.639784107809161 5.76038747742207 -0.11106615836466 0.911737850919367 LRP1-AS other 1 1 1 2.88184928564376 -0.11106615836466 3.73765272515073e-05 118.030206778486 26.4504057187473 4.4623212223482 1.63076113344818e-05 127.942281708275 40.0189974822293 3.1970386505831 0.00170939527806748 LINC00648 other 0.289107438290409 1 0.162113964276083 4.4623212223482 3.1970386505831 0.385105205855575 62.61080709113 48.1335104343424 1.30077375462851 0.195254072871914 -78.8441688239216 199.6955225024 -0.394821916064613 0.693513610828616 ITGB3 other 1 1 1 1.30077375462851 -0.394821916064613 2.54212247073302e-10 70.7840703200226 11.6247000518743 6.08910939672891 8.68242949937708e-09 -14.4769689502727 19.0502155480715 -0.759937278071283 0.448453881394036 USP3-AS1 other 2.95572579672129e-06 1 0.000105977734469397 6.08910939672891 -0.759937278071283 6.01249308083924e-05 128.341003488952 40.4557579202418 3.17237916397402 0.0018364412517789 -63.7440604751621 58.1588163657282 -1.09603434970739 0.274832099245701 BUB1B-PAK6 other 0.453101478572045 1 1 3.17237916397402 -1.09603434970739 0.000778189082872419 84.9250256578265 25.9151777476206 3.27703813127902 0.00129471571131965 -41.457899434692 47.5010900803646 -0.872777853404029 0.384134223795349 ZNF710-AS1 other 1 1 1 3.27703813127902 -0.872777853404029 1.76494973199827e-09 86.6486520062114 12.9153913079882 6.70894516007574 3.75903967276046e-10 51.0759645343884 74.8610116425707 0.682277241700316 0.496115896171136 ZHX1-C8orf76 other 1.96668348636567e-05 1 4.80442860575514e-06 6.70894516007574 0.682277241700316 6.02454142941959e-07 95.6028920225509 23.2266183447559 4.11609174454516 6.26177520791405e-05 -81.0474221406132 41.2082320144397 -1.96677746602217 0.0510061141055428 ST20-MTHFS other 0.00560222107521728 1 0.585914306204518 4.11609174454516 -1.96677746602217 7.32111535134892e-05 30.267170056016 7.5900043039994 3.9877671795347 0.000103889172517534 -6.81802982835805 13.2651300174672 -0.51398137970606 0.608021358465446 UBE2Q2P2 other 0.546887316745765 1 0.949027590947674 3.9877671795347 -0.51398137970606 2.60511369672442e-12 235.231381673265 38.6339847060294 6.08871653967794 9.8231330387718e-09 -270.502915921558 87.189471087478 -3.10247226583311 0.00231015860221992 THTPA other 3.26629155295307e-08 1 0.000119616291013124 6.08871653967794 -3.10247226583311 0.000145794355967514 161.698797962169 39.6829119827797 4.07477147927898 7.37492256608717e-05 -69.0319721715728 161.918451907521 -0.426337896381322 0.670460870658976 LINC01833 other 1 1 0.684097817230246 4.07477147927898 -0.426337896381322 7.11195860221898e-11 18.5247292763427 2.65662710269557 6.97302578052691 8.41905692234775e-11 -3.77704372493929 13.0749876426163 -0.288875510109738 0.773062630548033 ADNP-AS1 other 8.47247628282347e-07 1 1.09969721519706e-06 6.97302578052691 -0.288875510109738 1.81311506458753e-05 100.876158211721 24.6492339259849 4.09246626141102 6.8855624156066e-05 -50.3332899003937 43.0681946736925 -1.16868817654758 0.244346983674638 MRPL46 other 0.145738188891546 1 0.640701582772194 4.09246626141102 -1.16868817654758 0.232176598313435 0.712317939299537 5.42082128953818 0.131404062457152 0.895629441743729 -10.8959304420602 7.94116946816342 -1.37208133962417 0.172059676297219 ANP32AP1 other 1 1 1 0.131404062457152 -1.37208133962417 6.94768079140204e-12 73.4965879146864 12.0909921936914 6.07862338651034 9.15264413372019e-09 -44.477421679692 20.3422105064628 -2.18645961143512 0.0302913157039681 IQCH-AS1 other 8.58663869009378e-08 1 0.000111589037278317 6.07862338651034 -2.18645961143512 0.270527957807466 13.311863364383 10.0690032441018 1.32206366823656 0.18810728798461 -9.82087716376029 19.9753257016155 -0.491650414639598 0.623666524762777 HSP90B2P other 1 1 1 1.32206366823656 -0.491650414639598 2.54327303857368e-08 10.9316199230841 1.79782538977692 6.08046809509159 9.17278148096606e-09 1.91050053032983 3.2777490311757 0.582869680429607 0.560839114211485 CRTC3-AS1 other 0.000264118905055877 1 0.000111807033471495 6.08046809509159 0.582869680429607 0.0882743036561841 24.2928000000001 11.4344552153152 2.12452622731536 0.0353461986156435 35.7774400000001 19.81674442678 1.80541461450404 0.0731134654695695 SLC22A31 other 1 1 1 2.12452622731536 1.80541461450404 0.362310996028503 -2.10969809017808 4.3933644518395 -0.480201019811763 0.631770296607712 -12.666382466973 8.9982234579623 -1.40765369143671 0.161262089510364 IL21R-AS1 other 1 1 1 -0.480201019811763 -1.40765369143671 2.43533541558783e-10 480.551957195157 94.1189635621357 5.10579312614195 1.08066041633586e-06 -555.743069244972 219.394886004123 -2.53307212108184 0.0124335596844843 RBM15B other 2.83351275603644e-06 1 0.0117889244818078 5.10579312614195 -2.53307212108184 0.511623745736919 -21.4906675807695 20.1775013921309 -1.06508071356896 0.288539534169187 -58.8596823492445 72.0544888778507 -0.816877383573222 0.415285429783774 LINC00261 other 1 1 1 -1.06508071356896 -0.816877383573222 0.0121686658868293 7.911904746764 5.56367871420056 1.42206355779853 0.157043183297782 -22.9439324470842 15.4721527601867 -1.4829179108239 0.140153138775927 TGFBR3L other 1 1 1 1.42206355779853 -1.4829179108239 0.00204389203284483 131.837483383267 49.6681094897484 2.65436886440137 0.00878016507348244 -476.398166703041 203.092156670937 -2.345724101374 0.0202649169197315 HOXB7 other 1 1 1 2.65436886440137 -2.345724101374 0.000158244994555732 42.3347948002117 25.3703535064074 1.6686718531344 0.0972275353393642 -146.009316082695 52.1978130600307 -2.79723052601409 0.00581679160642664 MIR762HG other 1 1 1 1.6686718531344 -2.79723052601409 0.000289807021239373 17.2895437313473 4.45654142067907 3.87958780123103 0.000155068892398044 -2.19366547468611 13.829127637507 -0.15862645368436 0.874172369839841 SPDYE6 other 1 1 1 3.87958780123103 -0.15862645368436 0.348852674481244 17.1541023720784 12.412216021846 1.38203382392688 0.169349778408357 5.86675781113926 18.4294102890366 0.318336708507126 0.750744335625383 CCDC187 other 1 1 1 1.38203382392688 0.318336708507126 8.42333466365709e-05 98.3824198770339 22.2235858157154 4.42693725003922 1.77509685541865e-05 55.4052835282579 35.72110617103 1.55105173011669 0.122890031147984 FRRS1L other 0.623747931843807 1 0.175858845466326 4.42693725003922 1.55105173011669 0.00864703581214847 28.2775281352375 10.0928353293336 2.80174274250291 0.00573564470975846 -28.879908110617 36.358551167495 -0.794308551448441 0.42823815344614 JHDM1D-AS1 other 1 1 1 2.80174274250291 -0.794308551448441 0.0135531051270082 4.85841352947303 5.48511790504483 0.885744593567368 0.377307229131536 -16.6980857045113 9.68775473549276 -1.72362803977014 0.0870309340844802 LINC02166 other 1 1 1 0.885744593567368 -1.72362803977014 0.00140254316906916 188.228103339634 70.7790985438856 2.65937412614723 0.00875481390605494 -111.261709724848 149.347044070664 -0.744987692372432 0.457546042086574 SNHG19 other 1 1 1 2.65937412614723 -0.744987692372432 0.00191853291950325 6.30004402102142 51.3609059697167 0.122662244796383 0.90253766692029 -351.272036325495 111.33626022973 -3.15505510604259 0.00193699169354556 SLX1B-SULT1A4 other 1 1 1 0.122662244796383 -3.15505510604259 0.00849616734001091 14.35 5.24277137244172 2.73710199827324 0.00694270121978175 -23.1857142857143 20.5464474853737 -1.12845368048269 0.260918069142009 TBC1D3G other 1 1 1 2.73710199827324 -1.12845368048269 0.625909615095966 -26.2027959086027 27.7699545631548 -0.943566394716705 0.34685029912549 -60.3205364316732 109.401303165645 -0.551369450694217 0.582169315402365 MRC1 other 1 1 1 -0.943566394716705 -0.551369450694217 0.000664590277948984 4.71188765053893 1.43465154212179 3.2843429308069 0.00126542992444687 -7.81944491107397 6.95679559315651 -1.12400095796491 0.262761633464806 LINC02367 other 1 1 1 3.2843429308069 -1.12400095796491 0.0528700396078641 113.611246943765 72.5993742531304 1.56490669668363 0.120585404659322 -372.144458027711 279.123464251595 -1.33326110373963 0.185304390108375 SCX other 1 1 1 1.56490669668363 -1.33326110373963 0.00110771418733805 21.532551793502 6.9281254545466 3.10799103376097 0.00224880587029483 -6.20415667070628 14.6516818902066 -0.423443309593912 0.672570408231605 ATP2A1-AS1 other 1 1 1 3.10799103376097 -0.423443309593912 0.119132297992899 7.37153328714777 4.04659869771747 1.82166155771902 0.0704594779167187 2.65550204482988 6.97608768096412 0.380657779298851 0.703985190162502 C16orf95 other 1 1 1 1.82166155771902 0.380657779298851 0.383518183336356 11.348969830758 15.085399658866 0.752314826746265 0.453017606899703 -7.15814324258021 23.5927448362948 -0.30340442760048 0.76199384688209 MT1L other 1 1 1 0.752314826746265 -0.30340442760048 5.51734963856877e-05 10.8579834605598 2.86660378808217 3.78775173105596 0.000223217969451468 1.37845896946565 5.01245980802014 0.275006488283468 0.783708190413059 SNAI3-AS1 other 0.417828888128813 1 1 3.78775173105596 0.275006488283468 0.247963781763075 -40.8652726592958 41.1728246720606 -0.992530218288047 0.322526764084517 -120.309111787641 72.5558763539894 -1.65815806841985 0.0993615081849766 LINC01541 other 1 1 1 -0.992530218288047 -1.65815806841985 0.0279452841651614 18.8744985016457 14.7295650426674 1.28140229850451 0.20207002653723 -65.5022843761771 39.5382714324902 -1.65668052757489 0.0997169923090792 LINC01963 other 1 1 1 1.28140229850451 -1.65668052757489 3.77741613669403e-06 49.8098135553616 9.88018330978291 5.04138556883274 1.29076151413249e-06 22.2740496365805 20.3278192900479 1.09574221015854 0.274913401531579 FBXL19-AS1 other 0.0325462174337557 1 0.0140060531898516 5.04138556883274 1.09574221015854 0.000269558315916748 17.0102217566376 4.0866673207119 4.16237007363604 5.25538042106895e-05 10.1623745319338 7.09662073456898 1.43200192204594 0.154196427518574 ADPGK-AS1 other 1 1 0.496160465553119 4.16237007363604 1.43200192204594 0.000115155065873087 18.5431472081218 6.61421866903965 2.80352799566789 0.0057571543159877 -25.0062225397773 14.4555456793392 -1.72987053512049 0.0858110217155278 CAPN10-AS1 other 0.839134965017186 1 1 2.80352799566789 -1.72987053512049 0.342716879704022 15.0218636162462 10.4535548257007 1.43701007616223 0.152717757629206 -12.162373608416 41.8185458814581 -0.290836836911842 0.771562413003729 WFDC21P other 1 1 1 1.43701007616223 -0.290836836911842 0.000414374363475539 9.94099610232396 6.93057495098903 1.43436816896487 0.153591141158876 -34.6154714236937 12.6530648656569 -2.73573808331984 0.00699098683844081 LMO7-AS1 other 1 1 1 1.43436816896487 -2.73573808331984 0.875996804377298 -4.18132864393035 8.640924147941 -0.483898316006709 0.629140997804476 1.59965285054351 30.3704519360441 0.0526713548389782 0.958061584731906 TMEM178B other 1 1 1 -0.483898316006709 0.0526713548389782 6.11691807645887e-05 4.469692613473 5.18560102927778 0.861943020343683 0.390544338328906 -24.6784004400165 9.50604638113869 -2.59607406176577 0.0106817700564793 RBFADN other 0.460603931157353 1 1 0.861943020343683 -2.59607406176577 0.000197182143856241 1387.07701877403 330.23237166108 4.20030602026381 5.40450790031026e-05 552.635866696824 1390.2046363043 0.397521236992808 0.691746540572528 EPPK1 other 1 1 0.509320824525239 4.20030602026381 0.397521236992808 0.000976941813630021 24.3488393365316 36.6443440649962 0.664463779003494 0.507420537144343 -167.663387267257 57.4873292213006 -2.91652768598499 0.00408731359293275 SPINT1-AS1 other 1 1 1 0.664463779003494 -2.91652768598499 3.80051055873326e-16 288.285539173844 50.3945454439763 5.72057028462199 5.57697255992924e-08 -306.668789308713 100.355229274315 -3.05583268083074 0.00265732961949401 ZNF865 other 5.18959716795027e-12 1 0.00065652120975487 5.72057028462199 -3.05583268083074 0.000972774177090327 -61.0675932699343 19.3460692364281 -3.15658920288292 0.00192979172625 -132.725237746891 40.0827161530721 -3.31128352779353 0.0011635377569896 PYCARD-AS1 other 1 1 1 -3.15658920288292 -3.31128352779353 0.498810531530864 -39.7312202852609 70.2729477439258 -0.56538428457621 0.572646008033475 282.96782884311 277.316758613887 1.0203776730172 0.30917068232701 PECAM1 other 1 1 1 -0.56538428457621 1.0203776730172 1.42765393838705e-06 264.581090925647 67.7489432967044 3.90531686622657 0.000147586980947516 -75.5655192824294 119.779852699772 -0.630870030136324 0.529184270258451 VPS9D1-AS1 other 0.0128460301376067 1 1 3.90531686622657 -0.630870030136324 8.89922844084634e-11 48.5343976028708 6.97174917125487 6.9615811485276 9.80940063087905e-11 5.37926925592354 12.1569662173989 0.442484511326915 0.658776015201892 TMEM202-AS1 other 1.05616043135964e-06 1 1.27855727822877e-06 6.9615811485276 0.442484511326915 0.000658764933588331 46.9689569361845 13.5924332190319 3.45552236154593 0.000709845395612898 -29.6487776610239 42.9160526062895 -0.690855189619159 0.490696559255443 LINC01003 other 1 1 1 3.45552236154593 -0.690855189619159 0.0157129835761813 8.97958612975395 6.97441538815746 1.28750377343473 0.199875666890632 -11.1725702212279 11.215571096255 -0.996165966524753 0.320752705654355 SMG1P7 other 1 1 1 1.28750377343473 -0.996165966524753 0.0889579336234338 9.67043003020281 4.73551675239104 2.04210660332266 0.0436235698079474 26.6006040558033 18.2066836601123 1.461035109545 0.146963776782412 TMEM249 other 1 1 1 2.04210660332266 1.461035109545 0.190640541097108 65.1967484155414 57.7641426141525 1.12867161988427 0.260791569511078 -268.369276232647 241.470095009827 -1.11139756756101 0.268129375170193 TPBGL other 1 1 1 1.12867161988427 -1.11139756756101 0.0509646252645865 3.07759737455739 8.26507282873044 0.372361797449537 0.710135423711481 -25.1477675101477 12.319612207739 -2.04127914792238 0.0429302047159302 C15orf65 other 1 1 1 0.372361797449537 -2.04127914792238 0.0434694830403976 -132.885403188666 119.372177553856 -1.11320247239951 0.267344867685725 -455.607370775675 189.114094240493 -2.40916665997558 0.0171617245473351 HPR other 1 1 1 -1.11320247239951 -2.40916665997558 0.0400556103634449 27.6396906572175 67.6318867260769 0.408678391143574 0.683354695187762 -302.738974364549 146.607253088601 -2.06496587301578 0.0406362662085161 BOLA2-SMG1P6 other 1 1 1 0.408678391143574 -2.06496587301578 0.0024411320530955 105.112697603263 49.9669156202053 2.10364590846905 0.0370451207525989 -124.360037395886 74.6525599203579 -1.66585094373935 0.0977892432429943 DNAAF4-CCPG1 other 1 1 1 2.10364590846905 -1.66585094373935 0.011971135253262 160.137910972062 53.4278661387677 2.99727319365774 0.00318269774513115 16.7693122564358 219.810885127268 0.0762897262650417 0.93928892156099 ISY1-RAB43 other 1 1 1 2.99727319365774 0.0762897262650417 6.85714399057897e-07 138.226479566539 25.0747574675715 5.51257493697812 1.50655026082607e-07 56.1750270315479 43.5971103592944 1.28850344824682 0.199554634997749 LOXL1-AS1 other 0.00634285819128555 1 0.00173434066026297 5.51257493697812 1.28850344824682 0.0716944051285386 11.0256598062744 10.7760949658643 1.02315911665595 0.307806551406387 -47.7508574047331 35.6365206404864 -1.3399416257962 0.182200440276172 MIA other 1 1 1 1.02315911665595 -1.3399416257962 0.0428848096610734 340.807484220019 173.239407539783 1.96726304401471 0.051129734073231 -116.612220361543 300.961399018682 -0.387465704046334 0.698999894227406 PCDHGA9 other 1 1 1 1.96726304401471 -0.387465704046334 0.626145592843111 1.20928271777579 13.8026466751704 0.0876123794396019 0.930297125384579 36.306942502262 38.717485251247 0.937740203596841 0.349827480714367 SNORD3B-2 other 1 1 1 0.0876123794396019 0.937740203596841 0.0371243903870236 334.266649372701 168.736880001562 1.98099342224181 0.0495374715088656 -122.810340219475 294.394382772756 -0.417162647815441 0.677193908046907 PCDHGB3 other 1 1 1 1.98099342224181 -0.417162647815441 2.63137203998033e-16 212.257136730967 22.323797926684 9.5081104670479 3.92767826685435e-17 109.271753998122 71.1528839148966 1.53573190552358 0.126669524174661 CORO7 other 3.60076949950909e-12 1 5.55687921194553e-13 9.5081104670479 1.53573190552358 0.745521142572747 -25.1494301030588 33.6663697405957 -0.747019363740101 0.456183547467569 -48.3163743633948 93.8156964211792 -0.515013757894859 0.607277078139205 MMP12 other 1 1 1 -0.747019363740101 -0.515013757894859 4.17802084918085e-26 63.0692861520556 4.76795902164663 13.2277324250732 4.58011331564179e-27 37.3316721660589 14.458078820822 2.58206312392593 0.0107654935734821 LINC01569 other 6.03097309579256e-22 1 6.633378115044e-23 13.2277324250732 2.58206312392593 0.031225183596865 340.103850265699 170.113463805058 1.99927649851068 0.0475002541756826 -142.462537601274 296.796101585865 -0.480001377511553 0.631970199779651 PCDHGA4 other 1 1 1 1.99927649851068 -0.480001377511553 0.000925039675987478 5423.33418016303 3857.21047923468 1.40602495232231 0.161744336938357 -12614.3038335757 6163.16936772338 -2.04672354124113 0.0423965627316898 SPON1 other 1 1 1 1.40602495232231 -2.04672354124113 3.53492718139374e-06 205.766068909934 44.4969083828187 4.62427787431148 8.13087388720252e-06 -275.950413056621 203.060447470119 -1.35895698298029 0.17622757317573 OVCA2 other 0.0305347009928792 1 0.0831788398660818 4.62427787431148 -1.35895698298029 0.29402149901369 5.77846907993967 3.86051991662155 1.49681110439564 0.136450063282233 8.18570889894422 16.5455691243026 0.494737221636022 0.621477238075001 LINC01977 other 1 1 1 1.49681110439564 0.494737221636022 0.0028614982259342 443.063495876371 147.471857017845 3.00439354895189 0.00315376275051829 -1005.50508447434 622.008181822366 -1.61654639578599 0.10822737511751 MRPL12 essential 1 1 1 3.00439354895189 -1.61654639578599 0.592720375352629 7.13991114647573 7.26868986919756 0.982283090207555 0.32747169203001 4.3875472448777 14.0010201633534 0.31337339663018 0.754412927804583 C19orf84 other 1 1 1 0.982283090207555 0.31337339663018 0.461289299274895 34.6354746248524 27.7886283441461 1.24639022106137 0.214501563876049 39.1216489630714 148.965819892031 0.262621646975301 0.793190949167405 ALOX12P2 other 1 1 1 1.24639022106137 0.262621646975301 4.02470870476008e-10 1177.92972493345 177.077366352132 6.65206259387801 5.50754446137012e-10 -864.556182947488 724.616272323409 -1.19312278231812 0.234769889136618 GTF2I other 4.63646442788362e-06 1 7.01055334487802e-06 6.65206259387801 -1.19312278231812 2.92326879094459e-13 20.7806471541914 3.02435303370171 6.87110496778103 1.43426553274984e-10 -28.9567242572654 13.2384738221795 -2.18731589805706 0.0302081058877099 ZNF234 other 3.76809347152758e-09 1 1.86009896942326e-06 6.87110496778103 -2.18731589805706 4.89504013516569e-08 16.6063747393506 4.00109229663868 4.15046030137861 7.77615190600656e-05 -26.4942706781849 11.8665226066007 -2.23269036402017 0.0281668501967965 ROCK1P1 other 0.000498119284154461 1 0.719682858900908 4.15046030137861 -2.23269036402017 0.12557855455865 -0.315141944483849 6.64456423911663 -0.0474285345348314 0.962233138536479 -19.835430765681 10.5948507452422 -1.87217651693569 0.0630783031902306 MYZAP other 1 1 1 -0.0474285345348314 -1.87217651693569 0.062165249170624 0.355907854907416 8.55497216959091 0.0416024561917932 0.966870939677654 -29.2518305151828 15.6662563688269 -1.86718701816912 0.0638270005598926 TAPT1-AS1 other 1 1 1 0.0416024561917932 -1.86718701816912 0.00223882343421287 1.95623200767672 1.74746893066556 1.11946597352758 0.264695746666218 -21.8553683761596 6.96291734398486 -3.13882346959641 0.00203576434660833 TMEM220-AS1 other 1 1 1 1.11946597352758 -3.13882346959641 2.70737546151038e-09 369.452235772358 71.4861766928336 5.16816331302545 7.18604842465677e-07 -317.313516260163 196.307923849731 -1.61640707128592 0.108039824105059 SRSF8 other 2.98569365895365e-05 1 0.0079183067591293 5.16816331302545 -1.61640707128592 0.198104543642849 -5.65222563338487 29.9506468082786 -0.188717982271506 0.85055914342569 -194.603503417504 109.03739819666 -1.78474089290461 0.0762467376924579 IKBKE other 1 1 1 -0.188717982271506 -1.78474089290461 7.06756204631049e-15 126.617363259741 20.4000286071231 6.20672478937259 4.84787173389693e-09 -133.018559394353 53.5173801431554 -2.48552076051812 0.0140118114801009 LINC00667 other 9.45427774934954e-11 1 5.97500191202796e-05 6.20672478937259 -2.48552076051812 0.0822920067506269 1.99044408536246 0.950552143431568 2.09398726741786 0.0380014135610015 4.25630291530911 3.92561780644348 1.08423772388714 0.280058909711493 SNORA4 other 1 1 1 2.09398726741786 1.08423772388714 0.144459365733281 16.3812344719185 9.21898415520845 1.77690233502176 0.0776524875168531 9.77492521168892 16.9701174537743 0.576008105914133 0.565490518116761 LINC00908 other 1 1 1 1.77690233502176 0.576008105914133 0.218314070360973 1.11685743809864 2.94352742394439 0.379428242799256 0.70489598084662 -18.5401017447638 11.2944473137469 -1.6415235938281 0.102742749400515 LINC00672 other 1 1 1 0.379428242799256 -1.6415235938281 0.677430169905533 65.7772888048041 202.439149333751 0.324923756206664 0.745674107359212 501.550094595705 567.857380041768 0.883232502074401 0.378469735677567 SNORD3A other 1 1 1 0.324923756206664 0.883232502074401 0.0142984083600418 404.473417627922 179.286975472743 2.25601116066245 0.025477945869419 -832.241730750271 646.905188157856 -1.28649722708236 0.200200233362452 C1orf186 other 1 1 1 2.25601116066245 -1.28649722708236 1.11256457704381e-17 407.82865627062 41.986384552692 9.71335495102713 1.07760176073188e-17 -144.244260757825 173.123996356925 -0.833184675684356 0.406030931141644 KRT222 other 1.54613099271778e-13 1 1.52857809759818e-13 9.71335495102713 -0.833184675684356 0.791813549676708 -1.53095763528425 6.59110750067067 -0.232276235083174 0.816683205823404 -9.51114288378456 14.0254844356078 -0.678132932053151 0.49887444550889 MIR3687-2 other 1 1 1 -0.232276235083174 -0.678132932053151 6.41294786839366e-18 27.6242788342189 9.25583680444564 2.98452526960618 0.00330737866675851 -85.6919120202569 17.2588527912995 -4.96509895857363 1.81362835538859e-06 LINC00909 other 8.93259508588553e-14 0.026444515049921 1 2.98452526960618 -4.96509895857363 0.000357074491762263 322.916228413994 83.520384511423 3.86631635262442 0.000161807972832597 451.363436408331 316.123926534286 1.42780535898277 0.155346707747586 DYNLL2 other 1 1 1 3.86631635262442 1.42780535898277 0.788973361553271 -15.4144002735213 24.2256013867054 -0.636285557062804 0.525692087200489 -2.91196033941504 51.5506377582072 -0.0564873775776215 0.955038965282785 MIR3648-2 other 1 1 1 -0.636285557062804 -0.0564873775776215 0.00114412405720666 5.72699077646712 1.52249762264317 3.76157617016481 0.000238426287911411 0.206026531437173 5.86364841603902 0.0351362354662367 0.972016026224278 SEPT4-AS1 other 1 1 1 3.76157617016481 0.0351362354662367 9.81202984887346e-12 27.2770354685018 4.51127423314412 6.04641483953663 1.12630790753124e-08 -35.9429510374823 18.2483986267555 -1.96964959899458 0.0507204550279116 DSG2-AS1 other 1.20678155111295e-07 1 0.000136812621527819 6.04641483953663 -1.96964959899458 0.445274789379173 64.7724150695072 64.9414836975393 0.997396600471595 0.32011661423408 197.78304680431 182.165855319377 1.08573061871311 0.279273096984356 SNORD3C other 1 1 1 0.997396600471595 1.08573061871311 0.152994325645487 7.79640292424144 4.80943888025723 1.62106289701398 0.107010812804834 -3.89713398460247 10.9013947952497 -0.357489482566089 0.721205505997665 AGAP12P other 1 1 1 1.62106289701398 -0.357489482566089 2.24808556267005e-09 83.0198002453129 12.3638113934307 6.71474172514668 3.26006869568174e-10 30.6924829157179 47.6097050130567 0.64466862181357 0.520082791736443 TSPOAP1-AS1 other 2.48975476065708e-05 1 4.17614799916831e-06 6.71474172514668 0.64466862181357 0.557924212656003 -3.97160072386281 17.0546358154387 -0.232875141213366 0.816163624613221 43.8008143456443 47.8395648450143 0.915577189875069 0.361301815492015 SNORD3B-1 other 1 1 1 -0.232875141213366 0.915577189875069 0.00578815378695246 -5.74061023037755 2.32230417215423 -2.471945879963 0.0145120615756544 18.1596584292923 8.78990102599377 2.06596847627635 0.0404851759932432 MIR142 other 1 1 1 -2.471945879963 2.06596847627635 0.00578052735714634 46.9650443994392 60.9822754787433 0.770142537823304 0.442372627613961 -396.816550864621 149.525501068269 -2.65383862972943 0.00877706431902472 TIMM23 essential 1 1 1 0.770142537823304 -2.65383862972943 0.00417816153132173 55.1298439945647 18.3227602485444 3.00881762609671 0.00307392412880321 -48.0009517420895 66.5106071499034 -0.721703707108006 0.471592722936536 DTX2P1-UPK3BP1-PMS2P11 other 1 1 1 3.00881762609671 -0.721703707108006 1.07544881570339e-07 44.6700161584593 12.7069922294413 3.51538864208651 0.000580972488011177 -27.455781386051 25.5804070731695 -1.07331291904453 0.284854385640261 MIR1539 other 0.00106749049446718 1 1 3.51538864208651 -1.07331291904453 0.000539649443486672 12.8881403799108 5.83415488172718 2.2090843731758 0.0286551662440886 -67.2697690315154 23.711183507586 -2.83704813848679 0.0051705781886359 RARA-AS1 other 1 1 1 2.2090843731758 -2.83704813848679 2.39593341546137e-09 1910.32274340409 535.222918004615 3.5692095370767 0.000481318659408729 -1801.71385050338 1077.45561421892 -1.6721931063578 0.0965708867834305 RPL17 essential 2.64990235750028e-05 1 1 3.5692095370767 -1.6721931063578 0.00366831735428856 28.4259701117668 8.31599851648657 3.41822693395291 0.000828800414043135 7.51249529071904 37.7575774667063 0.198966559688406 0.842581747851501 MAFG-AS1 other 1 1 1 3.41822693395291 0.198966559688406 0.00446807343447543 36.4051724137934 12.1275047183863 3.00186833641054 0.00312267856821258 -4.94827586206892 27.489010695009 -0.180009237763051 0.857377446190729 ZNF488 other 1 1 1 3.00186833641054 -0.180009237763051 0.0281772015272843 28.8649375130908 13.3328306325868 2.16495193770345 0.0319621443540527 -48.9426423700809 54.5140070620892 -0.897799391527709 0.370721781008624 FSBP other 1 1 1 2.16495193770345 -0.897799391527709 0.0200119575528093 17.1580340890287 8.13906229609948 2.10810944367036 0.0366839502707711 -12.8273898174196 22.3721423602002 -0.573364392685046 0.56725659677965 LINC00668 other 1 1 1 2.10810944367036 -0.573364392685046 0.138373132433582 27.8990064181684 24.1760888486366 1.15399172268271 0.25029129864027 -44.9491483584302 53.9205861385178 -0.833617576837152 0.405787618604394 ESRG other 1 1 1 1.15399172268271 -0.833617576837152 0.525740646821832 -3.60637671063425 6.75511432637071 -0.533873526989117 0.594333798221387 10.8850831391034 18.8414428427564 0.577720253695333 0.56444468612083 GATA6-AS1 other 1 1 1 -0.533873526989117 0.577720253695333 0.000223485802442625 430.619805638815 116.529269470844 3.69537891719606 0.000304002539837971 -414.364425206442 424.363454633006 -0.976437581235143 0.330369143131089 SRGAP2 other 1 1 1 3.69537891719606 -0.976437581235143 3.97739817873661e-17 12.1753062347001 1.59730553125936 7.6224028505684 2.56210416960449e-12 -6.57710811519004 4.27110053178464 -1.53990946039424 0.125675392651577 NDUFV2-AS1 other 5.49398010428888e-13 1 3.45832820813213e-08 7.6224028505684 -1.53990946039424 0.360610233756961 -34.0306970363095 34.8928734293565 -0.97529075973658 0.331063006823811 -170.54121260309 155.390768084009 -1.09749900013937 0.274267921189462 BAHCC1 other 1 1 1 -0.97529075973658 -1.09749900013937 0.894457222135965 -17.8492055166456 52.0338687013151 -0.343030529194429 0.732037305308576 41.4976273487396 186.995662690604 0.221917592909094 0.824668281743421 RASSF5 other 1 1 1 -0.343030529194429 0.221917592909094 1.07596568726106e-12 239.0802532053 29.6622363290192 8.06008861076341 1.91796663276952e-13 -107.945040502119 120.025201144836 -0.899353131446624 0.369859652352085 STRADA other 1.36475487772193e-08 1 2.62895686353717e-09 8.06008861076341 -0.899353131446624 0.000144412691694133 5.72858181080672 2.63554499398761 2.17358528269302 0.0313372322693063 -6.08274882958407 4.85145731348373 -1.25379827885493 0.211905614743478 LINC00683 other 1 1 1 2.17358528269302 -1.25379827885493 0.135653609986985 31.5016623568526 15.8145490034412 1.9919418726388 0.0481453155471831 32.0152074867628 56.3432160378089 0.568217608758421 0.570714801700562 CCDC144A other 1 1 1 1.9919418726388 0.568217608758421 0.0103251332553244 70.2373088685015 23.0528522565831 3.04679473441054 0.00272505341658897 42.3905198776742 92.2770979399497 0.459382889406213 0.646611263654665 SNHG25 other 1 1 1 3.04679473441054 0.459382889406213 0.0395074785624923 62.9237233213892 172.485082807664 0.364806754863286 0.715746592014126 -939.666546190996 422.924829077718 -2.22182875439153 0.0277249670377444 NCOA4 other 1 1 1 0.364806754863286 -2.22182875439153 1.60438851815035e-06 174.111276444331 32.6681014208308 5.32970294788262 3.36613811395543e-07 99.0696124733132 74.0476965538832 1.33791619569451 0.182858430790789 GDF10 other 0.0143705079570727 1 0.00378825183344544 5.32970294788262 1.33791619569451 0.423839664328765 201.391311199832 156.419802348857 1.28750521465739 0.19983735526359 176.318291657912 725.982609712682 0.242868478251417 0.808428379284178 MYO15B other 1 1 1 1.28750521465739 0.242868478251417 0.000225333215579038 18.4371343128332 6.74282772035771 2.73433269801161 0.00696925436746684 -15.6138451870152 11.161026418079 -1.39896140391921 0.163797002116454 MIR3661 other 1 1 1 2.73433269801161 -1.39896140391921 3.42871954471474e-18 537.195420443358 53.0001242157256 10.135738894815 7.70419569464141e-19 513.727229520997 237.217963337526 2.16563375847739 0.0318682300329564 FXYD1 other 4.79026407592096e-14 1 1.09877238996976e-14 10.135738894815 2.16563375847739 1.25327181345514e-12 89.0241256388338 13.5122633975907 6.58839478030802 6.55759519010898e-10 -213.227934088718 53.6078163470466 -3.97755306256688 0.00010657902962485 AARSD1 other 1.58676744301555e-08 1 8.32191913264089e-06 6.58839478030802 -3.97755306256688 0.234577706460746 -14.0824301481555 13.6877647559435 -1.02883344353509 0.305192329552967 5.02156626149865 25.1150903162922 0.199942194045831 0.84179303779273 LINC01929 other 1 1 1 -1.02883344353509 0.199942194045831 0.235805251322481 16.0431873098853 11.3496530417156 1.41353988980268 0.159943496966338 -25.8920922163258 50.9025484884868 -0.508660037368898 0.611873044654616 LINC01532 other 1 1 1 1.41353988980268 -0.508660037368898 0.00101837077133207 29.2334651646825 9.77076602961247 2.99193175602446 0.00324876450767544 -40.7132974634897 41.2457683966731 -0.987090289407085 0.325209369490498 ZNF850 other 1 1 1 2.99193175602446 -0.987090289407085 0.00180671182562782 5.95522819179666 1.68275254344213 3.53898035394737 0.000529525042485648 7.85846331600226 6.67742005605392 1.17687119426875 0.241039481065608 PTGES3L other 1 1 1 3.53898035394737 1.17687119426875 2.10542659212152e-10 90.6544810663098 12.6183922265847 7.18431313898428 2.66127370331595e-11 30.3552506831743 49.478888604955 0.613499040480356 0.540445674225167 ASB16-AS1 other 2.45703283300582e-06 1 3.52006672737601e-07 7.18431313898428 0.613499040480356 1.93245946582544e-05 88.0951840792699 21.1598642420988 4.16331518346886 5.18764808072589e-05 -40.9913201105419 86.1303699284301 -0.475921793260653 0.634800197755035 ILF3-AS1 other 0.154809327807276 1 0.490128990666982 4.16331518346886 -0.475921793260653 8.88999830521733e-07 34.9148265413816 6.32440856917818 5.52064689677671 1.3796313998599e-07 -3.45059748748823 25.3002518600687 -0.136385894756024 0.891692070651649 TBC1D3P1-DHX40P1 other 0.00814323844757907 1 0.00159112889345842 5.52064689677671 -0.136385894756024 1.45505788646708e-08 26.5381684488407 6.15990409902648 4.30821130040561 2.96299439345694e-05 -48.736199507297 21.8445664406124 -2.23104448604156 0.0271616805503364 ZNF561-AS1 other 0.000153654112810923 1 0.287191725382122 4.30821130040561 -2.23104448604156 0.473291368365234 -1.71750380517502 11.9152924977586 -0.144142815251753 0.88557255436405 -35.4402822748028 31.7080204563572 -1.11770718464064 0.265399490003265 PCAT19 other 1 1 1 -0.144142815251753 -1.11770718464064 0.090328284335459 38.8135479543931 17.5673920704053 2.20940864750094 0.0285940390998526 9.3969651240786 77.3510756231037 0.121484608305458 0.903462553836197 RNF157-AS1 other 1 1 1 2.20940864750094 0.121484608305458 0.0281929513176789 6.73126448934966 2.95300127382628 2.27946548787898 0.0240309754889074 -15.4465102164253 20.8924487790699 -0.73933459786196 0.460844087855056 LINC01842 other 1 1 1 2.27946548787898 -0.73933459786196 2.31207310509791e-14 93.7228138067164 19.3401838841803 4.84601461744006 3.14767808035514e-06 -197.256941017583 51.8372572374835 -3.80531207725524 0.00020673637256143 CHMP1B-AS1 other 3.06419048618626e-10 1 0.0332835480216752 4.84601461744006 -3.80531207725524 6.75160101909349e-05 7.97534907559034 7.41266033569933 1.07590914926738 0.284259673025825 -32.5293073490256 13.5886067132702 -2.39386627602214 0.0183183783007571 PARD6G-AS1 other 0.506100012391248 1 1 1.07590914926738 -2.39386627602214 0.181603711646011 9.35230368990629 7.82540013705279 1.19512146677634 0.233876798798398 -27.8082233955758 25.6689468026308 -1.08334103496314 0.280350323617487 LINC01140 other 1 1 1 1.19512146677634 -1.08334103496314 2.76991075640439e-10 37.0661432226857 5.41801784334429 6.84127374519802 1.68370874062162e-10 -30.0528234428126 21.7812768541017 -1.37975489885724 0.169636526141443 MAP3K14-AS1 other 3.21586638818549e-06 1 2.17871911036437e-06 6.84127374519802 -1.37975489885724 0.000274325331893317 35.399113885812 8.64541491694341 4.09455349753502 6.85007256981685e-05 26.4006780116135 35.3253581383004 0.747357688724731 0.45600226457329 TBX2-AS1 other 1 1 0.637741756249949 4.09455349753502 0.747357688724731 6.2494868227052e-10 22.6204689235735 3.41645087304166 6.62104322999806 5.60565508688586e-10 1.03434623983006 15.8200490608931 0.0653819868603911 0.947954663721742 CEBPA-AS1 other 7.12816466997755e-06 1 7.13263553255357e-06 6.62104322999806 0.0653819868603911 0.802163308658563 -11.8453010543372 41.6733310902372 -0.284241761924144 0.776604480375972 -169.258502291443 258.284680109678 -0.65531762170164 0.513234695057278 LINC01764 other 1 1 1 -0.284241761924144 -0.65531762170164 0.388544350198499 3.58302702702703 2.60997962068901 1.37281800923838 0.171766657392777 1.71159459459461 10.4474280587545 0.163829277882452 0.870076255637022 KCNJ2-AS1 other 1 1 1 1.37281800923838 0.163829277882452 1.53745547602481e-29 78.2140337208064 5.97186481262631 13.0970871201636 5.86878216217519e-27 -8.44450488293556 19.1268842259493 -0.441499241757262 0.65945906471917 DM1-AS other 2.22715800256954e-25 1 8.49858344904589e-23 13.0970871201636 -0.441499241757262 0.201968405564434 6.68794882256939 3.77662296228327 1.77088072846065 0.0785209807439189 5.5278153415715 7.58745219479037 0.728546974617772 0.467364127272288 ZNF582-AS1 other 1 1 1 1.77088072846065 0.728546974617772 0.000437405675184793 18.2471507603668 6.09265377739852 2.99494299644221 0.00321870142162421 -30.050921245345 23.7811410406763 -1.2636450536139 0.208344270179401 ZNF571-AS1 other 1 1 1 2.99494299644221 -1.2636450536139 2.66733125877357e-21 24.110607441154 2.66980591528375 9.03084651327229 6.35331955017513e-16 -42.5960845355606 11.4444421800221 -3.72198870556734 0.000276050798671658 ZNF285 other 3.79561238123479e-17 1 8.92387264017599e-12 9.03084651327229 -3.72198870556734 3.17531455405446e-06 91.129235439892 19.0166246595222 4.79208256309885 3.85324249063425e-06 19.9432106792368 67.5289823674099 0.295328168440779 0.768140997881956 S1PR2 other 0.0275553797000846 1 0.0405206980315098 4.79208256309885 0.295328168440779 6.3471924728474e-18 50.4137621107591 6.22038738585087 8.10460168854308 1.44167737449463e-13 -83.3754223216641 27.228446763244 -3.06207045325162 0.00258942253103482 ZNF224 other 8.84163911467643e-14 1 1.97812552554409e-09 8.10460168854308 -3.06207045325162 1.18901735528682e-11 63.3159118130368 8.70494919015434 7.2735532890473 1.56387840078536e-11 -23.4100261177527 30.5295646029544 -0.766798558125761 0.444352794230816 LUZP6 other 1.45821088452375e-07 1 2.07714329192311e-07 7.2735532890473 -0.766798558125761 0.0140752802925345 85.0418207066229 80.5508834217984 1.05575279989554 0.292713440692835 -610.837345589366 253.857952258684 -2.40621709958062 0.0172881171982948 SMIM22 other 1 1 1 1.05575279989554 -2.40621709958062 1.18188414418112e-10 63.9762513800979 11.3527632426936 5.63530217379207 8.10619415388853e-08 -99.8746258704183 49.0314888485449 -2.03694866739463 0.0433677931897936 LIN37 other 1.39545060903465e-06 1 0.000945749671934175 5.63530217379207 -2.03694866739463 2.4497198790823e-06 20.5211038100789 9.90623096949865 2.07153496352584 0.0402269346493256 -45.3365481426527 17.2791222107182 -2.6237761148845 0.00970477532342451 MZF1-AS1 other 0.0215256885774962 1 1 2.07153496352584 -2.6237761148845 0.0208171028145684 10.8948229706206 5.36156344397595 2.0320235103926 0.0438371380498815 -3.18255370040139 9.328879162216 -0.341150704716107 0.733446258687651 CARD8-AS1 other 1 1 1 2.0320235103926 -0.341150704716107 8.35510460702789e-09 67.6192828668182 21.930456229685 3.08335048567247 0.00241867760103996 -105.046489348022 38.1340538152319 -2.75466358381398 0.00656959803592747 PTOV1-AS1 other 8.95082356550898e-05 1 1 3.08335048567247 -2.75466358381398 2.73158909718541e-05 23.725309348835 10.7669413032962 2.20353289578831 0.0290133720290968 -44.0607701219882 20.7394861694563 -2.12448706597553 0.0351953848980312 NAPA-AS1 other 0.2155496956589 1 1 2.20353289578831 -2.12448706597553 2.06381187781097e-05 6.77872493224266 1.51453910817889 4.4757675094924 1.46155055193563e-05 3.10155321308351 2.93712603455094 1.05598233667821 0.292608890939277 ZNF649-AS1 other 0.164981121512209 1 0.145921207105253 4.4757675094924 1.05598233667821 0.804957793012839 2.80964931383761 7.80128086796415 0.360152308497877 0.719226697770554 -4.29793491102956 16.165609729914 -0.265869025841713 0.790695683578936 RAET1E-AS1 other 1 1 1 0.360152308497877 -0.265869025841713 5.23869570480844e-05 28.0374616938827 7.05490347116641 3.97418076781243 0.000108521205177288 -5.29903643610323 22.2656357894078 -0.237991696541812 0.812205958120067 LINC00664 other 0.398088486608394 1 0.988194094344384 3.97418076781243 -0.237991696541812 1.94158285179006e-10 29.4193185681039 4.54317661483116 6.47549524534547 1.25373340454141e-09 11.1563423371598 10.2373670093001 1.08976676591011 0.277551955282137 ESPNP other 2.27009867031294e-06 1 1.57682050289173e-05 6.47549524534547 1.08976676591011 6.36285478428976e-07 22.9356892415575 6.93305202592974 3.30816632498611 0.00119378086469108 -19.1573168481269 12.2226197507347 -1.56736585435994 0.119286712873612 A1BG-AS1 other 0.00590282038338561 1 1 3.30816632498611 -1.56736585435994 0.0138725779676797 44.4590910326457 18.9670870353052 2.34401260192933 0.0207077001140755 -14.1089456087418 29.6746195537468 -0.475454978729807 0.63531991084358 MAN1B1-AS1 other 1 1 1 2.34401260192933 -0.475454978729807 0.100815730021038 -14.6744050886312 13.7758355010596 -1.06522795568389 0.28842932569304 11.625181621517 19.365662070148 0.600298692572825 0.549183863507676 MTRNR2L2 other 1 1 1 -1.06522795568389 0.600298692572825 0.822595862966904 -1.40888294064553 9.31965879427651 -0.151173231954669 0.88003437551654 -19.0383834611168 30.4669282471403 -0.624886870992773 0.532958246736595 TRABD2B other 1 1 1 -0.151173231954669 -0.624886870992773 5.4782420984601e-10 173.127789887873 31.1585412405834 5.55635093925315 1.18309610660845e-07 -150.749751476111 115.842001457348 -1.30133932062298 0.195085844953037 FBXO17 other 6.2676567848482e-06 1 0.00137014360106324 5.55635093925315 -1.30133932062298 6.53617299822163e-08 40.9785730094616 8.2303004029303 4.97898873713913 1.71516070226978e-06 -22.8430762278906 23.430109112433 -0.974945362749894 0.331136396942288 ZSCAN16-AS1 other 0.000660153472820384 1 0.018468850442041 4.97898873713913 -0.974945362749894 6.21024976038608e-10 39.9410072712759 9.63048019723137 4.14735365768764 5.55731757981768e-05 -44.9379216026012 18.9173881328394 -2.37548234920399 0.0187646012181411 ZNF587B other 7.08713702655259e-06 1 0.522665718381853 4.14735365768764 -2.37548234920399 1.67950334010633e-17 48.0668263101679 7.40946366085321 6.48722073692348 1.16271318782869e-09 -83.2771020684743 24.6761039074701 -3.37480756203431 0.000937572913013012 RAB11B-AS1 other 2.33014293406352e-13 1 1.46350708951998e-05 6.48722073692348 -3.37480756203431 0.524528286120259 5.45892671885316 7.3859926263167 0.739091818126477 0.46096186451978 -3.56349768531986 13.2805416849882 -0.2683247242353 0.788803868106896 SPIB other 1 1 1 0.739091818126477 -0.2683247242353 0.0224370849567308 56.6171804848846 23.6131286680002 2.39769923252951 0.0177449764926526 0.767617812364761 60.7745845189433 0.0126305727705221 0.989939539002372 LINC01224 other 1 1 1 2.39769923252951 0.0126305727705221 2.37621522276232e-05 110.723436831558 53.6122776034329 2.06526269319452 0.0405965001030267 -212.641318733004 94.4754075114644 -2.25075841781577 0.0258353692572195 RPARP-AS1 other 0.188719012991783 1 1 2.06526269319452 -2.25075841781577 0.000765699308534372 3.1357199831706 1.77412172637374 1.7674773588281 0.0790909982672012 -5.07143514541661 3.07434808761403 -1.64959692295367 0.10102475233101 NOP53-AS1 other 1 1 1 1.7674773588281 -1.64959692295367 0.211040424959555 5.60258887432609 3.17124337748348 1.76668524216895 0.079236612428341 5.40903884062149 6.3127985739067 0.856836912709237 0.392849343467388 ZIM2 other 1 1 1 1.76668524216895 0.856836912709237 0.0864516948523582 96.4525515175586 138.027672585116 0.698791406904876 0.485716256596195 -341.579187267673 257.936228644297 -1.32427766763514 0.187335470719248 KLK9 other 1 1 1 0.698791406904876 -1.32427766763514 0.405604402523277 4.81481981921117 5.21915469923389 0.922528665402067 0.357677483817823 -3.18249582258015 10.389449317027 -0.306319971874201 0.759769475076362 ZIM2-AS1 other 1 1 1 0.922528665402067 -0.306319971874201 0.0144897180664357 452.054014838337 153.152932447189 2.95165105633362 0.00366940494794831 499.58273788339 257.811104886615 1.93778595418962 0.054527797669089 KCNQ1OT1 other 1 1 1 2.95165105633362 1.93778595418962 0.222415979877662 21.6485058428887 18.3266416924177 1.18125874921456 0.239320978089477 -13.858780692242 35.6995208879163 -0.388206349764571 0.698399451405771 ZNF528-AS1 other 1 1 1 1.18125874921456 -0.388206349764571 5.23243802935373e-30 338.590461249692 31.5599214348078 10.7284950613425 1.73113444811308e-20 -378.367279172828 104.368585761943 -3.62529851689142 0.000389539041464435 EGLN2 other 7.58232594833649e-26 1 2.48244679859415e-16 10.7284950613425 -3.62529851689142 0.00362121216783465 11.9688572829818 5.62330101832945 2.12843972676702 0.0348513085460247 -9.68768829258034 10.0045875952085 -0.968324601127994 0.334362200750493 ARHGAP19-SLIT1 other 1 1 1 2.12843972676702 -0.968324601127994 1.17191869515026e-08 223.576456178551 137.011323755683 1.63181005810316 0.104749559488917 -745.950612411541 204.51245313963 -3.64745814232763 0.000361209645412106 SNHG8 other 0.000124422607864103 1 1 1.63181005810316 -3.64745814232763 0.00364174879275931 137.357884939832 43.7470612349175 3.13981970588226 0.00205696507160068 -18.9018505789843 170.156839102203 -0.111084871338207 0.911705902578562 COMMD3-BMI1 other 1 1 1 3.13981970588226 -0.111084871338207 0.420413596860004 -268.106168761987 240.650174664055 -1.11409089619927 0.267149197369919 54.0653037690676 626.903020808207 0.0862418938408788 0.931397347963421 RMRP other 1 1 1 -1.11409089619927 0.0862418938408788 5.79854589427256e-09 248.767517410814 40.5856686701984 6.12944237613315 7.00278024487468e-09 -125.951909605896 145.9600569626 -0.862920392242444 0.389514451486726 C7orf55-LUC7L2 other 6.26880796629807e-05 1 8.58610885824084e-05 6.12944237613315 -0.862920392242444 2.40872868298051e-05 3.13961432073002 2.13900704878316 1.46779054445664 0.144174445407186 -28.2717900256266 7.19773429316249 -3.9278735327148 0.000128380641227113 MKNK1-AS1 other 0.191132620994503 1 1 1.46779054445664 -3.9278735327148 0.703216054828483 0.624637333885967 2.48265472314464 0.251600566145087 0.801678852681404 -2.50515180167344 4.81703345628651 -0.520061117367594 0.603753512704566 SPACA6P-AS other 1 1 1 0.251600566145087 -0.520061117367594 0.000815409155936091 25.9777433637104 7.39294238269464 3.51385713819695 0.000589438643613041 -4.35429944209503 26.7725440687143 -0.162640480894132 0.871027950870292 C8orf44-SGK3 other 1 1 1 3.51385713819695 -0.162640480894132 0.552761742572343 -18.2629119329627 22.5095697704163 -0.811339893175797 0.418464667376991 -67.942873257594 71.9514006991168 -0.94428840296959 0.346550979428775 SCARNA2 other 1 1 1 -0.811339893175797 -0.94428840296959 2.00522856029722e-06 41.9977996582918 9.40124362035856 4.46726000880828 1.50822736236831e-05 -38.606358357895 30.7268585532323 -1.25643688211771 0.210823886681031 TSNAX-DISC1 other 0.0177863773298363 1 0.150475843943486 4.46726000880828 -1.25643688211771 0.533139862202747 -0.888530294266502 1.61258881262469 -0.550996191533975 0.582461533674266 9.24500578410816 9.53589739936767 0.969495098040925 0.333869338022141 TERC other 1 1 1 -0.550996191533975 0.969495098040925 0.000421683905895846 90.7789224888784 28.8533291845798 3.14622003957151 0.00198577160662583 -61.0042267063006 57.6722989386831 -1.05777345153451 0.291815141476298 BIVM-ERCC5 other 1 1 1 3.14622003957151 -1.05777345153451 0.000157681106188956 9.76814066649864 5.26766334732089 1.85435932830952 0.0656512977741473 -23.9057139841507 11.0810189562448 -2.15735701550068 0.0325701944883132 POC1B-AS1 other 1 1 1 1.85435932830952 -2.15735701550068 0.00574314591804145 36.7532435847001 20.59456870369 1.7846085593487 0.0763326872101923 -51.731166404406 39.7226991406016 -1.30230743437901 0.19479419975668 HMGN3-AS1 other 1 1 1 1.7846085593487 -1.30230743437901 1.05737790886842e-05 8.38347708189798 1.76321786342443 4.75464618173504 4.50858342718621e-06 5.47557686710411 3.69828943251187 1.48057013033323 0.140750982330417 CAHM other 0.0871913823652896 1 0.0471823255655036 4.75464618173504 1.48057013033323 0.0299940161919045 10.0875911220279 4.91996364155105 2.05033855064175 0.0420380670027074 -4.11056992263641 11.6585341051373 -0.352580340338423 0.724888305618274 LINC01235 other 1 1 1 2.05033855064175 -0.352580340338423 0.00517677103453844 -7.12770633241111 80.0192515133207 -0.0890748938238264 0.929139646945194 -535.897862840399 184.169631848295 -2.90980579948072 0.00416000580887876 URGCP-MRPS24 other 1 1 1 -0.0890748938238264 -2.90980579948072 0.00014106706383718 356.95585635873 93.8047462205501 3.80530698861942 0.000204343981229635 -566.00358172854 372.001165954356 -1.52151023579853 0.130195879943672 TAF15 other 1 1 1 3.80530698861942 -1.52151023579853 0.313318464363909 2.75321458435228 2.53422176926737 1.08641422693966 0.279136547551011 -5.91143524288849 9.59050717666037 -0.616384007018384 0.538627989916652 YTHDF3-AS1 other 1 1 1 1.08641422693966 -0.616384007018384 0.0234720371380353 155.337284565301 88.9561258764152 1.74622357971285 0.0828610926073278 -458.901340482573 307.03800195137 -1.49460763021529 0.137160432156827 HSPE1-MOB4 other 1 1 1 1.74622357971285 -1.49460763021529 0.77410625590759 -2.82085816448154 11.837656795933 -0.238295315796847 0.81197300054603 -32.1092967818833 45.6489522133631 -0.703396139999108 0.482884947761762 GAS2L2 other 1 1 1 -0.238295315796847 -0.703396139999108 0.00132563121601504 1336.05636377868 566.115560642532 2.36004175942855 0.0195263029717158 -2528.83668425996 1631.26081440688 -1.550234433345 0.123137895202412 RPS10-NUDT3 other 1 1 1 2.36004175942855 -1.550234433345 0.0797289870361732 79.6831148192293 37.8026711112868 2.10786995936481 0.0366830168162364 166.461521652761 145.776512771471 1.14189534711752 0.255293178462508 RASL10B other 1 1 1 2.10786995936481 1.14189534711752 1.50587743807088e-10 80.9523039411708 11.7207183894549 6.90676981148218 1.18352336770131e-10 -54.2519914643944 53.4598744090761 -1.0148170392107 0.311764404105853 GPR75-ASB3 other 1.76895422650186e-06 1 1.53822532100139e-06 6.90676981148218 -1.0148170392107 3.08989223026199e-09 49.6252476424439 7.50170298184252 6.61519761080374 6.05374925760475e-10 8.18105694395416 29.7916322199374 0.274609221930417 0.783991828207757 LPP-AS2 other 3.39826347484214e-05 1 7.69552605626715e-06 6.61519761080374 0.274609221930417 0.0145167346184504 7.42354502827192 3.17210634706906 2.34025729784598 0.0205968644865288 -16.3461572350174 12.5590501685806 -1.30154406707532 0.19508108386634 CTAGE15 other 1 1 1 2.34025729784598 -1.30154406707532 2.75135502481002e-05 25.2910796717814 9.17470869220777 2.7566084679355 0.00654164040641071 -86.4758671572 28.278746148577 -3.05798095512631 0.00262562676328249 TMEM56-RWDD3 other 0.21694434370627 1 1 2.7566084679355 -3.05798095512631 1.53782306589373e-13 34.5418464633878 4.08898876447808 8.4475278492962 2.15414344124658e-14 9.14083381420978 16.2866471224791 0.561247121366893 0.575450189447274 TMCC1-AS1 other 1.99717081567619e-09 1 2.9852119808795e-10 8.4475278492962 0.561247121366893 0.000193538262084763 107.275130180578 30.762373211588 3.48721892952551 0.000639475302975037 -109.579379700965 111.010779757178 -0.98710575622166 0.325169859199676 SRXN1 other 1 1 1 3.48721892952551 -0.98710575622166 0.0216037297601044 6.15699558681558 2.63586468589978 2.33585419606387 0.0208320268336285 -11.0927324200494 10.4359542858304 -1.06293417125357 0.28953148811655 CTAGE6 other 1 1 1 2.33585419606387 -1.06293417125357 0.0616354579376967 -18.9227651966628 21.3281947360143 -0.887218324423408 0.376363037914826 -190.713289630513 82.2468296796809 -2.31879198715946 0.0217386757594854 MMP28 other 1 1 1 -0.887218324423408 -2.31879198715946 0.352043493910299 38.8054099933576 86.9092671161651 0.446504858238988 0.65585983351482 492.590818510592 344.853101629664 1.42840767904585 0.155199548623232 CCL5 other 1 1 1 0.446504858238988 1.42840767904585 0.104065782200493 -27.8106612879988 13.0222040956403 -2.13563395902461 0.0343113509688266 5.91231810978239 51.3892692102646 0.115049663103624 0.908557600941477 MILR1 other 1 1 1 -2.13563395902461 0.115049663103624 1.27458929319334e-06 22.1611965182327 5.01506528040389 4.41892483530104 1.89105461687119e-05 -1.42842710884508 10.549655468629 -0.135400356257388 0.892476872250614 ATP2B1-AS1 other 0.0115184634425882 1 0.186874017239211 4.41892483530104 -0.135400356257388 4.11091251530296e-09 174.690990646026 38.2082339027317 4.57207708397995 1.03146877280603e-05 -328.284038072316 118.128254442138 -2.77904756675397 0.00617964803242869 MROH7-TTC4 other 4.48295009793788e-05 1 0.104611562937988 4.57207708397995 -2.77904756675397 1.56561723532436e-05 16.3644008080049 3.77462287354057 4.33537371977381 2.71801091304308e-05 -3.06971390989805 8.53471039612309 -0.359674056578706 0.719617820011394 BMS1P4 other 0.126642778165387 1 0.264462461839091 4.33537371977381 -0.359674056578706 3.89548945592617e-08 27.3505853449799 11.4402488944085 2.39073341825174 0.018055116033957 -57.0918434907382 23.0303299516707 -2.47898504322543 0.0142828494989931 SNORD58B other 0.000399443488810669 1 1 2.39073341825174 -2.47898504322543 1.88323238698735e-07 173.988013486328 35.9976330759213 4.83331815509582 3.20406641903578e-06 8.26206350412571 75.2756869982386 0.109757397555456 0.912743753299553 GTF2H5 other 0.00183257343577739 1 0.0338637779827892 4.83331815509582 0.109757397555456 0.000124087419482967 24.3106341695338 5.5699572144002 4.36459980458786 2.31641334848088e-05 21.3281966275711 10.9965088113865 1.93954253967282 0.0542511478521072 FGF14-AS2 other 0.899687824454352 1 0.226869523350217 4.36459980458786 1.93954253967282 1.35648648654106e-05 5.16644146043464 2.41248214457048 2.14154598908108 0.0338029704521499 -14.9301023920236 5.41740051241045 -2.75595322107364 0.00655881271873324 ARF4-AS1 other 0.110567213517962 1 1 2.14154598908108 -2.75595322107364 1.4917809841924e-10 21.489609500956 3.17100613784216 6.77690567813897 2.45515295885044e-10 3.13388136927753 9.37462626074087 0.334294006194319 0.738612535038409 CASC15 other 1.75314101262291e-06 1 3.15953634274464e-06 6.77690567813897 0.334294006194319 2.08310193131148e-13 680.898706221766 99.0478675889687 6.87444084154721 1.4574058825707e-10 -390.442445319139 285.406225126657 -1.36802357813278 0.173297503232626 NUDT3 other 2.69595051950332e-09 1 1.88967246734118e-06 6.87444084154721 -1.36802357813278 6.29286619147613e-20 418.242105207158 49.9148520382201 8.37911138926962 3.00951399807003e-14 -676.926633753963 217.596404547756 -3.11092747676995 0.00222054114184755 KMT2B other 8.88741492222173e-16 1 4.16125500513143e-10 8.37911138926962 -3.11092747676995 7.05091213572644e-09 536.479459997919 87.8264057035021 6.10840732579959 8.79298548336714e-09 -340.021246227272 347.790044328985 -0.977662390777453 0.329869639604115 POM121C other 7.58678145804164e-05 1 0.000107292008868046 6.10840732579959 -0.977662390777453 0.00251447165821388 6445.4139761567 2749.41054800979 2.34428938989207 0.0203746777343973 -3868.62677737751 5738.45847137664 -0.674157841635374 0.501248577888801 CD24 other 1 1 1 2.34428938989207 -0.674157841635374 7.06232662802185e-32 131.27607357504 9.06047514039508 14.4888729940619 1.95631648621298e-30 -9.86390903987897 35.2545579039454 -0.279791029198386 0.780018218533644 FAM47E-STBD1 other 1.02509671005737e-27 1 2.83900648479228e-26 14.4888729940619 -0.279791029198386 0.00159628352842582 9.16992576387013 4.73624621553692 1.93611677825972 0.0546497088391864 -8.21956195767064 6.95114364999328 -1.18247620413924 0.238804508835406 LINC01023 other 1 1 1 1.93611677825972 -1.18247620413924 0.0516479930755803 2.47572507072937 2.85138662833489 0.868253026835267 0.386633667060666 -10.1687822442773 6.50504053176712 -1.56321581619953 0.12009520032799 MUSTN1 other 1 1 1 0.868253026835267 -1.56321581619953 0.00470137633191798 59.1377081779768 20.8488954956664 2.83649117960561 0.00525377970221299 -22.279393487447 46.6351367995772 -0.477738353876749 0.63359779594083 ZSWIM8-AS1 other 1 1 1 2.83649117960561 -0.477738353876749 3.46347055816925e-05 84.1052696073251 28.5127432996374 2.94974316302966 0.00381352607313675 -64.6180622752568 52.5149710629646 -1.23046934935527 0.220888598277888 ZNF595 other 0.269319470603241 1 1 2.94974316302966 -1.23046934935527 0.0902409222149319 31.8636655048496 134.626810128973 0.236681426785082 0.813222608660998 -418.121566467411 255.005544176971 -1.63965676831418 0.103144558172651 AFAP1-AS1 other 1 1 1 0.236681426785082 -1.63965676831418 0.138613555593559 515.480125523013 261.842310437169 1.96866627346197 0.0512221290051366 1197.60041841005 1335.34778003026 0.896845328475335 0.371539351486365 DOC2B other 1 1 1 1.96866627346197 0.896845328475335 0.180071800767924 24.7901945216356 15.8798980150817 1.56110539866764 0.120620353114559 -15.4852782014584 37.7190888744317 -0.410542212538841 0.681998006224033 PCDHB16 other 1 1 1 1.56110539866764 -0.410542212538841 0.103277705060623 17.692510602694 16.589670401522 1.06647752333107 0.28801771589121 -39.1869956988008 30.0882654002718 -1.30240129091811 0.194887658457831 GAS6-AS2 other 1 1 1 1.06647752333107 -1.30240129091811 0.00218178780996434 271.64814090996 89.782421958836 3.02562723285085 0.00290567215842158 -288.33054878708 295.337119789971 -0.976276023115976 0.33044891879191 STAG3L5P-PVRIG2P-PILRB other 1 1 1 3.02562723285085 -0.976276023115976 0.0770250498299656 7.6580051798779 3.60739991958467 2.12286005172379 0.0353855753695046 -0.174641284004769 7.86729089644526 -0.0221984017501728 0.982318806691578 JMJD1C-AS1 other 1 1 1 2.12286005172379 -0.0221984017501728 1.7982830043688e-17 308.415500795979 42.152246030854 7.31670384942784 1.42741307266672e-11 -213.576328690284 94.9994950967397 -2.24818382953294 0.02602216469538 DCP1A other 2.49367904215822e-13 1 1.8977456801104e-07 7.31670384942784 -2.24818382953294 5.2353117297885e-09 10.3275760398309 1.78312882261405 5.79182833503343 3.83174818289225e-08 -4.67898760981298 4.97860949213814 -0.939818159508533 0.348792216868139 TBC1D8-AS1 other 5.67800535053592e-05 1 0.000454713556863823 5.79182833503343 -0.939818159508533 1.24083138402704e-07 10.9841634691957 3.06237739465903 3.58680921833889 0.000451534964106421 -6.66821110548035 6.0526577851663 -1.10169967345959 0.272345221512346 RBAK-RBAKDN other 0.00122482465917309 1 1 3.58680921833889 -1.10169967345959 0.000246068788490388 273.432137863913 71.8783124963795 3.80409790335139 0.000209720029828506 -137.617266976155 218.451318310714 -0.629967665291975 0.529714079501496 ARL2-SNX15 other 1 1 1 3.80409790335139 -0.629967665291975 0.542995931648053 -5.37117356706743 4.98730017474867 -1.07697018003094 0.283307091701952 -2.96388863748702 7.90366182035644 -0.375001955404179 0.708214604333878 DGCR9 other 1 1 1 -1.07697018003094 -0.375001955404179 0.000253812447860663 37.9551663962698 9.22051637381415 4.11638186599405 6.33069603644837e-05 -2.86325648611437 40.0814550887131 -0.0714359416287923 0.943145962605154 LINC02035 other 1 1 0.592173307249381 4.11638186599405 -0.0714359416287923 0.962161469966648 0.903164633835777 4.17055202752315 0.21655757508249 0.828861783790731 2.42866350346948 9.56044163193916 0.254032564286141 0.799835303600402 FAM95C other 1 1 1 0.21655757508249 0.254032564286141 2.03202153240701e-27 78.1319050014107 5.92687748705727 13.1826421538205 6.8022871771637e-27 -28.0112997902278 27.5710961637798 -1.01596612712941 0.311270622753187 C2orf15 other 2.93870954016702e-23 1 9.8483513750976e-23 13.1826421538205 -1.01596612712941 7.95905911712962e-06 4.02411074535378 1.79296229632054 2.24439228510936 0.0263006910057145 -10.6457428255957 4.31032506938249 -2.46982365697092 0.0146620146592548 CDC37L1-AS1 other 0.066390854747958 1 1 2.24439228510936 -2.46982365697092 8.61711369389317e-07 30.7646236895755 6.05263248226126 5.08285011187097 1.09916726060161e-06 6.21678412448743 17.0352334892627 0.364936830974807 0.715676026811896 ZBTB8B other 0.00790103154593065 1 0.0119853198096 5.08285011187097 0.364936830974807 0.000398195532357893 71.8554847742829 17.7501819715473 4.04815482395978 8.15123343814762e-05 68.4632938739178 72.731693190231 0.941313076472052 0.348018678889318 C1QTNF3-AMACR other 1 1 0.752773184525815 4.04815482395978 0.941313076472052 0.359826778983178 -0.748190110765222 2.83952452047269 -0.263491336444128 0.792531122388085 -6.85220444508797 5.61219862221561 -1.22094831390391 0.224008618669404 RBAKDN other 1 1 1 -0.263491336444128 -1.22094831390391 0.00534678895129346 48.8290571870169 21.5802494326788 2.26267343847636 0.0250540112180649 -89.929778464709 62.8797829493396 -1.4301858919768 0.154689436037998 PAXIP1-AS1 other 1 1 1 2.26267343847636 -1.4301858919768 0.64373753387498 2.47169021239205 4.76760742354197 0.518434089222005 0.604914296511375 -6.58780564822824 13.6907173336404 -0.481187763042985 0.631079600304578 HIST1H4K other 1 1 1 0.518434089222005 -0.481187763042985 1.56795144663933e-06 75.2951355142527 14.3963829742494 5.23014257462668 5.52296742626113e-07 -34.0023445719152 55.2088874623631 -0.615885342646964 0.538891355413414 CWC25 other 0.0140613885734616 1 0.00613435992034824 5.23014257462668 -0.615885342646964 0.00871925466933674 17.6041556584714 9.81909063216819 1.79284990005069 0.0752869821034679 -30.6025704783515 20.8944403985649 -1.4646274269424 0.145400239507237 SMIM11B other 1 1 1 1.79284990005069 -1.4646274269424 0.00144905241949377 167.661439807625 45.9579677700243 3.64814738211685 0.00036241689830919 193.038675417062 176.244843941189 1.09528693776413 0.27512341181815 EPOP other 1 1 1 3.64814738211685 1.09528693776413 4.74481115138537e-10 164.821882098121 25.8214062977427 6.38314893455393 1.99191016715598e-09 -207.065075090329 101.253000429666 -2.04502655932814 0.0425770634608193 ZNHIT3 essential 5.44609423956013e-06 1 2.49008689996169e-05 6.38314893455393 -2.04502655932814 0.0946019178545714 331.364083262925 166.485423667394 1.99034892042517 0.0483456374333464 769.416794684702 652.098111187375 1.17990955882958 0.239879511164074 LHX1 other 1 1 1 1.99034892042517 1.17990955882958 3.76235549713478e-12 773.6991069603 146.960594879061 5.26467048937167 5.04398767499635e-07 -521.91727180989 230.944750924367 -2.25992264262726 0.0253370900300454 CYFIP1 other 4.69128106937735e-08 1 0.00562101986501594 5.26467048937167 -2.25992264262726 0.131721669758491 40.0669052863436 21.0718539168346 1.90144186859295 0.0591745539039426 84.7616798052398 59.7787912654308 1.41792227662951 0.158301421980495 HIST1H2BG other 1 1 1 1.90144186859295 1.41792227662951 3.42606025159119e-07 62.0078671328669 80.0366292409277 0.774743610781129 0.439770324646189 -384.040100524476 115.515879297721 -3.32456544380952 0.00112509856980683 TAF9 other 0.003253386814911 1 1 0.774743610781129 -3.32456544380952 0.550309348445938 9.22955805778521 8.4323885187117 1.09453662355625 0.275497811640937 10.1150215237702 25.8748647777219 0.390920749177369 0.696417983696844 HIST1H3G other 1 1 1 1.09453662355625 0.390920749177369 0.523672190097495 -549.201753230929 653.771801914029 -0.840051148769413 0.402199108255166 -1105.99384211957 1047.53902972504 -1.05580203766716 0.292733894823652 RN7SL2 other 1 1 1 -0.840051148769413 -1.05580203766716 0.0857685944641774 3.65216213287093 2.7030325425134 1.3511350956489 0.178686578217914 -4.53998716142425 5.04396450968711 -0.90008308993948 0.369518789630715 FAM27E3 other 1 1 1 1.3511350956489 -0.90008308993948 0.00835871363811598 33.5349157054125 11.5067831478019 2.91436062317892 0.00412996933773198 -28.9908243929983 47.0867761519179 -0.615689303074478 0.53906481447729 CASTOR2 other 1 1 1 2.91436062317892 -0.615689303074478 1.08546443978624e-07 172.51568737525 29.4836738853899 5.85122763349844 2.78020808787062e-08 93.5312500000002 71.755973980987 1.30346290086987 0.194337173123097 NATD1 other 0.00107721491004386 1 0.000331845637368237 5.85122763349844 1.30346290086987 0.468936365736326 35.5519931971501 28.8567512967753 1.23201648139522 0.219784909184743 37.0164557908297 70.8430338867198 0.522513700500464 0.602049236634841 ANTXRL other 1 1 1 1.23201648139522 0.522513700500464 3.8195966615948e-14 234.671846516166 26.9811914525403 8.69760873714384 4.78986152718901e-15 62.6545234177149 103.584752952611 0.604862411038223 0.546160627180706 SOCS7 other 5.03804799664354e-10 1 6.6799408858178e-11 8.69760873714384 0.604862411038223 0.0322050423303736 7.23234100135318 3.12712762732413 2.31277448932964 0.0220854438053937 -11.6935240672724 12.2552289639425 -0.954166103438557 0.341524548134033 TBC1D3H other 1 1 1 2.31277448932964 -0.954166103438557 0.350345340285252 -131.370663849269 132.871887086124 -0.988701724121054 0.324401269346374 95.8343370311675 306.306034560021 0.312871201407521 0.754813091086847 SNORA73A other 1 1 1 -0.988701724121054 0.312871201407521 0.502554701271531 3.91204414587332 3.33941684014638 1.17147524047996 0.243277709243076 3.61022578038186 9.27533558954526 0.389228588607742 0.697662768569822 HIST1H3B other 1 1 1 1.17147524047996 0.389228588607742 0.0810371997400557 71.0379666179715 140.754136301768 0.504695410624881 0.614614287973428 -518.005159605881 299.516423870647 -1.72947163601818 0.086062374289436 CBSL other 1 1 1 0.504695410624881 -1.72947163601818 0.00050938064349723 47.9752920251887 14.6312023355719 3.2789712646205 0.00130639477722407 161.451611145828 52.0499867811365 3.10185690968015 0.00231466084271446 ADRA2B other 1 1 1 3.2789712646205 3.10185690968015 0.0147196384078992 13.9507158590309 5.65413763081648 2.46734635234133 0.0147440582450901 -7.42548690006956 16.0402361630158 -0.462928776397359 0.644090819372583 HIST1H2BE other 1 1 1 2.46734635234133 -0.462928776397359 0.000232899710760005 15.4934351068747 5.14104514510055 3.01367419845361 0.00303418129778141 -10.396129773758 9.8151200403906 -1.0591953772319 0.291224852045945 ZNF658 other 1 1 1 3.01367419845361 -1.0591953772319 0.000107848277093844 8.64990139436699 2.43097598432533 3.55820108883865 0.000500289882256909 -15.3364951947114 10.8284165853027 -1.41631928120751 0.158755337019285 TMEM269 other 0.7883008388888 1 1 3.55820108883865 -1.41631928120751 0.00231529124997611 16.140418232315 4.83179872356581 3.34045748917363 0.00105246519086422 -13.2232069923215 18.3633878427937 -0.720085373435632 0.472578268384852 TBC1D3D other 1 1 1 3.34045748917363 -0.720085373435632 4.26897650558075e-10 193.075421472937 30.9722042100458 6.2338288926273 4.69177524412993e-09 -272.295878035009 126.741003792056 -2.14844343888711 0.0333394278905582 RCC1L other 4.91188436732121e-06 1 5.7849588760122e-05 6.2338288926273 -2.14844343888711 9.11663011453911e-06 133.689204371017 30.3845458322096 4.39990793705718 2.11224089578306e-05 17.7457313761146 48.6959037330405 0.364419386759917 0.716086962802775 PI4KAP1 other 0.0756224468001019 1 0.207907871371926 4.39990793705718 0.364419386759917 0.000530651998907476 16.9393889887274 5.00472357396324 3.38468024025412 0.000906789227087358 -30.1953929096552 19.0205936324342 -1.58751054216128 0.114475101176412 TBC1D3 other 1 1 1 3.38468024025412 -1.58751054216128 0.225038577161062 1.79065241566786 1.49405930804803 1.19851494918721 0.232594229372033 -2.61954775732114 4.29035821304759 -0.610566210848019 0.542404689302792 HIST1H2BO other 1 1 1 1.19851494918721 -0.610566210848019 0.0181409462176804 25.0129405286344 9.9534863385267 2.51298285624982 0.0130355903143119 -6.79203377386198 28.2370684868286 -0.240536080331079 0.810245335234621 HIST1H3E other 1 1 1 2.51298285624982 -0.240536080331079 5.89953364507626e-05 88.3604692570003 19.6038672739009 4.50729787252931 1.31400445245925e-05 100.935058386488 79.5994582525265 1.26803700178806 0.206749397097517 NPHP3-ACAD11 other 0.445237804193905 1 0.131889018626123 4.50729787252931 1.26803700178806 0.304632727110494 2.05530212239533 2.31362973289738 0.888345310042958 0.375786864978254 -2.35199288668961 3.99702073354223 -0.588436498953366 0.557130265391759 PANO1 other 1 1 1 0.888345310042958 -0.588436498953366 0.0159408620125673 7.34194857916102 2.87875008472913 2.55039456815226 0.0117557635018747 -11.7140150782912 11.2818361201692 -1.03830750185684 0.3007867017098 TBC1D3I other 1 1 1 2.55039456815226 -1.03830750185684 3.40569566672775e-10 68.0937820567618 11.4188729696628 5.96326644824498 1.64705388423766e-08 -11.2753016897475 22.7987968658413 -0.494556873158553 0.621622331505953 ZNF280B other 3.93902760813731e-06 1 0.000198502934128323 5.96326644824498 -0.494556873158553 0.00382579681416073 994.19471970342 303.386942957204 3.27698585183893 0.00130009702030921 -498.973708732028 1163.46276847695 -0.428869511127734 0.668625385206067 MLLT6 other 1 1 1 3.27698585183893 -0.428869511127734 6.21722979601311e-10 511.593660647262 75.6897595758966 6.75908687666356 2.65625917644419e-10 -86.6051905770025 320.424546001001 -0.270282634891311 0.787302367260913 PPP4R3B other 7.09323747427135e-06 1 3.41302741581314e-06 6.75908687666356 -0.270282634891311 5.71720462304994e-13 314.044647133758 38.0894999458922 8.2449138891262 7.21792519356859e-14 250.19949044586 144.93424847897 1.72629653150728 0.0863259404744568 SYNRG other 7.31287643334317e-09 1 9.93908299154395e-10 8.2449138891262 1.72629653150728 5.36771581467754e-06 -13.9217516152188 11.2241652269637 -1.24033737331083 0.216925345483073 -87.0825066892904 20.2603627556552 -4.29817115021711 3.20574642320442e-05 NUDT18 other 0.0454860238135775 0.462557151404166 1 -1.24033737331083 -4.29817115021711 5.34658961782127e-06 29.4698015008474 6.6523590940171 4.42997755899128 1.94059021797857e-05 -28.2892156862745 20.9079410831991 -1.35303689510617 0.178322210049575 ZNF2 other 0.0453176936006531 1 0.191589519753746 4.42997755899128 -1.35303689510617 0.220622576469007 6.0603964501949 3.52306872422877 1.72020386900672 0.0873532848941559 -3.76080285311435 15.541798881657 -0.2419798944608 0.809109532143279 SCARNA16 other 1 1 1 1.72020386900672 -0.2419798944608 0.000408533697106004 35.5674904183965 17.3988126477521 2.04424814143808 0.0425997112381877 -65.6754830725009 37.2018263860623 -1.76538330110336 0.0794434095252772 LENG9 other 1 1 1 2.04424814143808 -1.76538330110336 0.271790681670948 -26.2850203343877 23.1052385721326 -1.13762168056946 0.257068561787163 90.0995255309533 91.378010171755 0.986008836935728 0.325695703691004 CCL4 other 1 1 1 -1.13762168056946 0.986008836935728 0.000289241231014125 12.0239989342265 3.49328139428479 3.44203560408804 0.000740086325302848 -1.93886647381241 6.71384526998863 -0.288786290991733 0.773125870110742 FGD5P1 other 1 1 1 3.44203560408804 -0.288786290991733 0.000208953565029219 170.480706409282 78.0246317890727 2.18496008888769 0.0305089103715624 -145.897901141443 153.106104740339 -0.952920207779296 0.342227309374347 PRAG1 other 1 1 1 2.18496008888769 -0.952920207779296 0.218135550622323 3.64286572461021 15.3072199299223 0.237983496760845 0.812210240561638 -102.399110930381 60.6723751274927 -1.68773862429494 0.0934856598229161 CCL18 other 1 1 1 0.237983496760845 -1.68773862429494 0.610389326457132 86.6421678169129 137.877461045544 0.628399791814364 0.530655174032762 483.615403566541 494.689162464464 0.97761471295883 0.329768892940825 FCGBP other 1 1 1 0.628399791814364 0.97761471295883 0.000917996649221851 40.0867096879595 26.3447888384175 1.52161818163837 0.130182389552039 -325.992035615095 100.124115832238 -3.25587929446795 0.00139381250747801 HNF1B other 1 1 1 1.52161818163837 -3.25587929446795 0.14429939865518 16.264793824241 8.21707565024503 1.97938956832604 0.0500426351246016 13.7308706406806 12.8558799414743 1.06806151762381 0.287618996354873 STPG3-AS1 other 1 1 1 1.97938956832604 1.06806151762381 1.55709558177355e-09 19.6761349959078 3.45660911611494 5.69232283285268 6.51575046975599e-08 8.51008617784412 6.67218610667999 1.27545695545334 0.204145919714557 XKR5 other 1.74021002219012e-05 1 0.000764883947644656 5.69232283285268 1.27545695545334 0.587890171227245 -8.75974241641446 8.73751759526785 -1.00254360817066 0.317653781713431 -13.3511329249384 34.6701812505727 -0.385089793111996 0.700702229914775 CCL15 other 1 1 1 -1.00254360817066 -0.385089793111996 3.54966665348798e-11 452.430601428681 60.6545095327637 7.45914203105199 6.21644181011637e-12 15.8837660342582 237.574498896255 0.0668580428794018 0.946782575997133 AATF essential 4.27805825078371e-07 1 8.32568051628886e-08 7.45914203105199 0.0668580428794018 0.848274998694534 -13.9843191495975 25.6946979402188 -0.544249213675654 0.587188161510123 -4.77372330836415 54.6767877783077 -0.0873080424497442 0.930558969338417 MIR3648-1 other 1 1 1 -0.544249213675654 -0.0873080424497442 0.683035535367228 4.95635054613145 5.86574759057865 0.844964852236766 0.399503607772992 2.18493188184946 17.2004326366312 0.127027728197737 0.899092045521174 HIST1H2BH other 1 1 1 0.844964852236766 0.127027728197737 0.184598300668172 237.86134623533 173.858514540187 1.36813170677556 0.173263729286714 -693.901963875735 667.468347683275 -1.03960280106796 0.300153924560458 ARHGAP23 other 1 1 1 1.36813170677556 -1.03960280106796 1.09010730272732e-07 77.4034079291898 18.5003135509078 4.18389708456544 4.97761022623109e-05 -40.7462751538416 29.0727613654063 -1.40152752061336 0.163223063443793 TUBGCP5 essential 0.0010813864443055 1 0.470981479605985 4.18389708456544 -1.40152752061336 0.0786004880197458 116.973316134647 55.7411721377682 2.09850836730773 0.0377657645725612 20.8691604761756 118.61389639924 0.175941952078975 0.860609177026425 U2AF1L5 other 1 1 1 2.09850836730773 0.175941952078975 0.184709435287272 112.409813159493 64.5095204069786 1.74253059781441 0.0834381440705773 241.050759602976 256.794943403551 0.938689665801427 0.349379318629726 PRSS2 other 1 1 1 1.74253059781441 0.938689665801427 0.0553146252266278 4.21765899864682 1.97937027594132 2.13080849495987 0.0347245068907065 -6.60647593272763 7.7571621075281 -0.851661450560152 0.395750675989878 TBC1D3F other 1 1 1 2.13080849495987 -0.851661450560152 2.49437989260219e-07 127.045044585987 25.6511779142348 4.9527957355707 1.92630383403223e-06 -221.303184713375 97.6052245075725 -2.26732929338435 0.0247798805180987 DUSP14 other 0.00239884514271553 1 0.0206885031775062 4.9527957355707 -2.26732929338435 0.064482338812341 63.0239589275527 49.6630920050189 1.2690301063249 0.206332650282197 -57.7877484751414 88.1762194497102 -0.655366592441625 0.513203257742423 UHRF1 other 1 1 1 1.2690301063249 -0.655366592441625 0.4526097750432 -656.002148549883 668.911497458375 -0.98070096125191 0.328373697735675 -1220.53022354713 1072.17283641867 -1.13837077576411 0.256843050849639 RN7SL1 other 1 1 1 -0.98070096125191 -1.13837077576411 0.371386959993754 32.4270184315143 41.491720247643 0.781529862776811 0.435747828679908 -85.4000144560896 118.791108081172 -0.718909149308838 0.473338125357413 HIST1H4I other 1 1 1 0.781529862776811 -0.718909149308838 0.998879749652955 0.150394710208491 3.2115141650158 0.046829844889615 0.962711973772797 0.315970582281918 15.4046325982831 0.0205114000782552 0.983663045112713 PIK3R6 other 1 1 1 0.046829844889615 0.0205114000782552 8.13751428548827e-15 139.825436942675 15.5745147968463 8.97783582773242 9.83623131239979e-16 43.8287898089172 59.2625421891094 0.739569856268697 0.460701700844146 TADA2A essential 1.08766015939836e-10 1 1.3792363546247e-11 8.97783582773242 0.739569856268697 0.917567860536604 -2.1602586019333 8.89054948588123 -0.242983699192489 0.808395199406913 -7.76250271967179 18.9185601092897 -0.410311497007646 0.682242672598832 KCNE1B other 1 1 1 -0.242983699192489 -0.410311497007646 2.75172776024617e-07 594.490797054255 102.942850508999 5.77495954420154 4.20117900996472e-08 216.14221732378 394.776956057081 0.547504645363665 0.584835108056746 PIP4K2B other 0.00263477933043571 1 0.000497671665520421 5.77495954420154 0.547504645363665 0.606585336747075 -8.78780721824488 8.87496598359979 -0.990179256403238 0.323639731085027 0.356114842424566 35.2155719160688 0.0101124253575468 0.991944677692172 CCL14 other 1 1 1 -0.990179256403238 0.0101124253575468 0.0650425943806042 345.181920649235 188.444238728921 1.8317456823171 0.0691148063623314 -116.992539396281 327.376100682188 -0.357364325473031 0.721357220788504 PCDHGB5 other 1 1 1 1.8317456823171 -0.357364325473031 0.000298913733890725 236.435142475321 76.6581731513009 3.0842783327052 0.00245895529145779 -82.7244736554124 126.726939116439 -0.652777335522983 0.514970321535817 HERC2P2 other 1 1 1 3.0842783327052 -0.652777335522983 0.354721132564838 -20.2312094847048 17.9051155981404 -1.12991225182629 0.260281477531997 -74.2870298245383 65.5215396412383 -1.13378028403019 0.258660093005375 RAB7B other 1 1 1 -1.12991225182629 -1.13378028403019 1.37892227494137e-06 427.67636719929 91.5197947281316 4.67304771027672 6.78711789834327e-06 -55.7180390900353 172.246572509775 -0.323478361735607 0.74680556884166 DACH1 other 0.0124227107749468 1 0.0699073143529357 4.67304771027672 -0.323478361735607 0.837435763207049 -1.5050624469504 2.54658280785284 -0.591012568807609 0.5553840905173 -1.57038923244805 9.69597627540995 -0.161962982152785 0.87154869742336 YWHAEP7 other 1 1 1 -0.591012568807609 -0.161962982152785 0.052488137402379 17.0962279735683 7.06928628400931 2.41838104820283 0.0167962090423748 12.3833516886931 20.0548746605419 0.6174734022675 0.537865039536509 HIST1H4E other 1 1 1 2.41838104820283 0.6174734022675 3.65218313255166e-09 987.333762200531 156.144964247646 6.32318670639047 2.98663894994655e-09 -586.11645962733 638.959028282606 -0.91729897173954 0.360509203952728 GTF2IP1 other 3.99658400195128e-05 1 3.70701626467366e-05 6.32318670639047 -0.91729897173954 0.145618213722717 49.0112885462556 25.9202107680366 1.89085223823464 0.0605853522521305 95.2235972640852 73.5331060652683 1.29497585998291 0.197331556250676 HIST1H2AE other 1 1 1 1.89085223823464 1.29497585998291 0.00142563394486501 27.3810910414487 7.62759312596969 3.58974195257272 0.000449466742232366 -7.70194276354699 30.4086668448231 -0.253281171543967 0.800402429541904 TYW1B other 1 1 1 3.58974195257272 -0.253281171543967 6.44241465194163e-09 70.750270746878 10.8356538395746 6.52939562248468 9.33602013422608e-10 57.1422834743772 42.4896479387364 1.34485189326039 0.180676322994618 PIGW other 6.94878844358424e-05 1 1.17932606335544e-05 6.52939562248468 1.34485189326039 0.903477320331692 30.7876911871814 147.450059688761 0.208800805182231 0.834885144786742 -135.67960214858 423.945194857251 -0.320040429268847 0.74938009147664 RPPH1 other 1 1 1 0.208800805182231 -0.320040429268847 0.459214399225154 5.55754405286344 4.5330391497913 1.22600839507846 0.222129652197162 9.34733171033309 12.8597892811373 0.726865075778788 0.468449044075758 HIST1H2BF other 1 1 1 1.22600839507846 0.726865075778788 1.71486574145052e-07 639.372212948612 108.879457225262 5.87229427150623 2.58263303435667e-08 232.768153094081 417.775381733052 0.557161008694415 0.578231583768954 PCGF2 other 0.00167393812691298 1 0.000308805431918027 5.87229427150623 0.557161008694415 5.67524846876865e-05 117.702630128751 26.4708953148935 4.44649222206425 1.67544658305596e-05 168.934532338059 101.513601234559 1.66415662811248 0.0981413354387005 SRCIN1 other 0.429219041692973 1 0.166455618026609 4.44649222206425 1.66415662811248 0.905339718607828 -1.54171199452958 16.3089343827925 -0.0945317430522152 0.924830115232817 -14.9517607932117 34.7044416016475 -0.430831331759619 0.667293712762765 MIR3687-1 other 1 1 1 -0.0945317430522152 -0.430831331759619 0.188051566480149 92.6865123415431 223.425226381423 0.41484354225656 0.678830055451913 -537.511472308881 458.971335048918 -1.17112209687691 0.24334692509318 MARCKS other 1 1 1 0.41484354225656 -1.17112209687691 0.0447204674393343 38.4905462184873 15.3486660841161 2.50774536416034 0.0131937899891642 38.7077731092436 74.1832560697824 0.521785847103181 0.602573990941887 CEBPB-AS1 other 1 1 1 2.50774536416034 0.521785847103181 1.55780741944958e-09 27.0864279206442 4.7475033141189 5.70540474191774 5.77893230193407e-08 -17.4021669361657 14.8302109940208 -1.17342679367016 0.242436356871673 ZNF670 other 1.74084979123491e-05 1 0.000680064753291601 5.70540474191774 -1.17342679367016 0.923415209614813 1.53902937802384 5.87676791878555 0.261883640683548 0.79386391662579 -5.29845628210884 25.2691701993599 -0.209680659883444 0.834275475456202 GPIHBP1 other 1 1 1 0.261883640683548 -0.209680659883444 0.053587216915963 -38.0212471003578 21.0951688057923 -1.8023675207528 0.0734432285756596 115.598800402945 83.6137457371273 1.38253345049719 0.168809608290287 CCL3 other 1 1 1 -1.8023675207528 1.38253345049719 0.685581788130133 0.859899397838021 1.68153383665227 0.511377992577286 0.609848486610135 -2.10766849652971 4.77143931425464 -0.441725935868672 0.65933227052338 HIST1H3F other 1 1 1 0.511377992577286 -0.441725935868672 4.38598677401264e-11 22.2799642522769 2.99603716639877 7.4364779256251 9.67331826058098e-12 17.4766192867478 7.06758584111209 2.47278486312631 0.014612632771378 PGM5P2 other 5.26625431955697e-07 1 1.28962998089981e-07 7.4364779256251 2.47278486312631 0.000192148569711281 658.550488010602 178.987305595774 3.67931393692174 0.000324084407505119 -1100.16026027233 685.499267617836 -1.60490362607603 0.110590714841022 PSMB3 essential 1 1 1 3.67931393692174 -1.60490362607603 0.438071153261043 -7.52600738234389 6.23176601877926 -1.20768452468601 0.22903217029279 -23.5812649362328 38.8472528624812 -0.607025290043292 0.544733894413349 SRD5A2 other 1 1 1 -1.20768452468601 -0.607025290043292 0.616283672277503 -0.356995969400328 11.7173644274205 -0.0304672583678374 0.975733349159113 30.1204655753886 32.8681082026278 0.916403992274205 0.360869526394738 SNORD3D other 1 1 1 -0.0304672583678374 0.916403992274205 2.63912309653703e-06 220.024547868343 54.0685161205847 4.06936538405529 7.55267270548743e-05 -574.811031511447 207.348097581014 -2.77220306439927 0.00626442954894937 CISD3 other 0.0231028835870851 1 0.699981706344575 4.06936538405529 -2.77220306439927 0.00531978334135648 6.55674838138455 2.43966875542089 2.68755681147926 0.00802776970290087 -12.7313928393559 11.8665660843063 -1.07287927686118 0.285083391620602 SNORA67 other 1 1 1 2.68755681147926 -1.07287927686118 2.70281354851163e-06 19.9691490146874 3.79426492460925 5.2629822670445 4.68343068724699e-07 17.8047457376928 15.0555179105033 1.18260599492705 0.238787960365783 RDM1 other 0.0236361044817342 1 0.00522858201924254 5.2629822670445 1.18260599492705 2.87317701953011e-14 297.127347770701 34.464722677882 8.62120233920771 8.07112900931351e-15 -51.1648407643313 131.141618751906 -0.39014952881682 0.696972167116412 DDX52 essential 3.79719074901099e-10 1 1.12382400325681e-10 8.62120233920771 -0.39014952881682 4.55682738204254e-10 115.837315709202 29.7309573827125 3.89618518563271 0.000149170847310686 -148.388211037678 59.1859879180359 -2.50715103789725 0.0132814386293058 ZNF8 other 5.23442761375226e-06 1 1 3.89618518563271 -2.50715103789725 1.27666575961082e-08 49.1843612072051 9.72761235297328 5.05615966411036 1.22310095193193e-06 -7.90146725515923 16.7375555553676 -0.472080121199377 0.637551100191362 TSC22D1-AS1 other 0.000135339337176343 1 0.0132902149436924 5.05615966411036 -0.472080121199377 0.274890258237008 7.7110562601073 6.29009160415953 1.22590524039556 0.222307227712983 -4.89725082985782 14.8381878767851 -0.330043727072612 0.741863809530251 GLIDR other 1 1 1 1.22590524039556 -0.330043727072612 1.56548062768526e-09 132.254814849824 19.713735026533 6.70876496370778 3.47144545055762e-10 168.725571283409 39.2054832766305 4.30362176874332 2.96563326745276e-05 SSTR3 other 1.74895495724998e-05 0.428207787487504 4.44206159853352e-06 6.70876496370778 4.30362176874332 0.85722753105836 -10.7322662000779 65.2016029095824 -0.164601263176931 0.869475098969606 181.878857758712 359.402963433735 0.506058314102482 0.613544092038887 MIR650 other 1 1 1 -0.164601263176931 0.506058314102482 9.29105615485195e-07 268.352775994097 49.7750069618385 5.39131568981673 2.62002077814422e-07 -80.6526581113847 195.181809355372 -0.413218108684188 0.680029177220142 MYO19 other 0.00849852906484308 1 0.00296900754579302 5.39131568981673 -0.413218108684188 0.00048437823576155 1.95057208389901 1.31562558653105 1.48261945029675 0.140259593256585 -6.70850441634829 3.03315234109353 -2.21172683134329 0.0284878532240768 SNORA61 other 1 1 1 1.48261945029675 -2.21172683134329 0.00491144973934829 9.61583074661004 3.24253839339395 2.96552564071421 0.00350995470468233 -12.8920927952949 12.323358964154 -1.04615087759719 0.29715214379603 TBC1D3C other 1 1 1 2.96552564071421 -1.04615087759719 1.02473703965679e-10 227.533928265952 31.0827156790843 7.32027183902276 1.31177133702682e-11 91.3207504134103 121.953840487918 0.748814059877494 0.455118920517184 GGNBP2 other 1.21298123384174e-06 1 1.74518058678048e-07 7.32027183902276 0.748814059877494 2.4218714462431e-07 33.9146697038722 7.22414180631303 4.69462956475119 5.83580321911098e-06 -53.1276082004555 30.9671473605387 -1.71561195424012 0.0882312462188625 ZNF229 other 0.00233129345415361 1 0.0604764287596471 4.69462956475119 -1.71561195424012 1.86438047962449e-08 208.212073873166 33.1667686443787 6.27773166887801 3.41998386631931e-09 7.93623791222995 130.056233230545 0.0610215882399249 0.951422177405649 DHRS11 other 0.000195610799922201 1 4.23804400714289e-05 6.27773166887801 0.0610215882399249 6.23912426809772e-09 485.883256854201 74.1951472740141 6.54872016170759 8.44078776537496e-10 231.011896039796 289.897153921523 0.796875350153775 0.426766383404801 ACACA other 6.73326291013106e-05 1 1.06826609958586e-05 6.54872016170759 0.796875350153775 2.90410406761238e-05 13.0426643095473 5.54699874099324 2.35130111228616 0.0200825662888881 -19.3561420614223 8.88991786121623 -2.17731393738369 0.0311090689332239 TMEM191B other 0.228175456592305 1 1 2.35130111228616 -2.17731393738369 0.394942858277123 0.887153497085033 13.1434444978352 0.0674977930808893 0.946275305915881 -28.1430408803241 22.9270473037856 -1.22750393923064 0.221556140397311 NR2E3 other 1 1 1 0.0674977930808893 -1.22750393923064 0.000369987082873202 33.0682078091815 8.45119398227938 3.91284449020098 0.00013722140278403 -18.7241872243097 32.1190019928542 -0.582962921091864 0.560782143181149 TBC1D3E other 1 1 1 3.91284449020098 -0.582962921091864 1.81681003889403e-09 36.9457715646363 6.78971368650034 5.44143291904838 2.07182178727716e-07 -86.630117520547 26.5942769819619 -3.25747218393287 0.00138652612721872 MRM1 other 2.02319965931239e-05 1 0.00236270556621087 5.44143291904838 -3.25747218393287 0.000658028301325825 40.4084094406986 13.195717670724 3.06223658682457 0.00260443727392193 -27.1851108211784 23.0622939810071 -1.17876872281511 0.240356743759147 GOLGA6L10 other 1 1 1 3.06223658682457 -1.17876872281511 0.0467095962760526 8.08344659994234 3.32678792282383 2.42980520173374 0.0162800367064675 4.98966184768731 9.55324317506673 0.522300307471495 0.602226655601682 HIST1H2AM other 1 1 1 2.42980520173374 0.522300307471495 0.628686437285368 3.01076129619859 3.12652121296041 0.96297485004037 0.3370796414193 4.31234323384631 12.8371134888539 0.335927795418386 0.737385546270857 NKILA other 1 1 1 0.96297485004037 0.335927795418386 0.975467343079927 33.9969846271971 324.895873383698 0.10463963199387 0.916839420553707 141.686657175307 638.505455758495 0.221903596746866 0.824772517047986 MIR6723 other 1 1 1 0.10463963199387 0.221903596746866 0.215677953934738 49.7765048400829 29.3442318776706 1.69629605735089 0.0919041615279561 25.5593895504662 83.7090277667798 0.305336117648824 0.760533464485659 HIST1H3H other 1 1 1 1.69629605735089 0.305336117648824 1.56155067432002e-14 291.310223421742 47.09847758371 6.18513035594378 5.40933395072297e-09 -970.88078086 178.87365340806 -5.42774613455875 2.19194616411577e-07 MRPL45 essential 2.07545700123874e-10 0.00320265254038956 6.65672635975968e-05 6.18513035594378 -5.42774613455875 0.000127097197977991 9.14399156298 2.64335530537621 3.45923665440753 0.000700829109980854 -1.84079901813077 5.33586347573875 -0.344986153881292 0.730575500517872 CEP83-AS1 other 0.919675324568742 1 1 3.45923665440753 -0.344986153881292 2.10804143851245e-10 8.58450787285485 2.78615867168851 3.08112669966939 0.00243576397152855 -12.9158164769712 4.18705698164176 -3.08470043125776 0.00240835944038613 EPB41L4A-AS2 other 2.45987355460018e-06 1 1 3.08112669966939 -3.08470043125776 0.000144283848831215 132.248446399115 35.6209903355633 3.71265495858716 0.000291115587407146 -13.0936635325456 59.0927084408685 -0.221578327986909 0.824951768652526 HEIH other 1 1 1 3.71265495858716 -0.221578327986909 0.00989207969128056 5.81230365451149 2.09305003963676 2.77695398793246 0.00615982590798574 -4.65302819421799 7.24440245294902 -0.642292890882098 0.521625806240608 SND1-IT1 other 1 1 1 2.77695398793246 -0.642292890882098 9.6997568589917e-13 10.3560739030023 1.32637543134978 7.80779985683505 7.9323973322408e-13 -5.29935334872978 6.69056747916566 -0.792063358636154 0.429526515704631 C17orf100 other 1.23206311622913e-08 1 1.07896468513139e-08 7.80779985683505 -0.792063358636154 0.000138750678916099 4.2248299333575 3.69383925622583 1.14375034761913 0.25449051099235 -16.2313944446932 7.48437115960826 -2.16870517222488 0.0316297874917098 MIR3622A other 0.9980336334435 1 1 1.14375034761913 -2.16870517222488 3.17331170266633e-06 15.1059045718561 3.75027918442317 4.02794134223358 8.76384077641129e-05 -3.2318176958985 5.22564886795641 -0.61845289983335 0.537178782457761 MIR3911 other 0.0275411722674411 1 0.806448628245367 4.02794134223358 -0.61845289983335 9.93737679458083e-18 16.6546404068676 1.90389793799257 8.74765399684603 3.56308293452714e-15 3.48509547411895 3.82096677606634 0.912097821930511 0.363142824013308 GVQW2 other 1.38169286951852e-13 1 4.97584531806716e-11 8.74765399684603 0.912097821930511 0.697569205361185 2.43516302489665 3.88812611294276 0.626307623302265 0.532194761171937 -1.84863861001461 8.27370093344861 -0.223435512702786 0.823541985548962 LINC01670 other 1 1 1 0.626307623302265 -0.223435512702786 0.68617222851611 9.34102131972593 11.5536016067934 0.808494323902731 0.420228545732684 1.6196980589511 26.2688645941857 0.0616584722626193 0.950926002858402 LINC01667 other 1 1 1 0.808494323902731 0.0616584722626193 0.000309177482155269 22.0667878027635 7.83917078537079 2.81493902951366 0.00573358029953156 -40.6577044402219 26.9350819528848 -1.50947023333142 0.133897721973175 UCKL1-AS1 other 1 1 1 2.81493902951366 -1.50947023333142 4.05923034660614e-07 27.7573409438316 5.27201662875011 5.26503288939973 4.60730598538867e-07 3.39516290626377 13.8989422851211 0.244274912192299 0.807340963754581 LINC01101 other 0.00383272529326551 1 0.00514497859388353 5.26503288939973 0.244274912192299 0.00150789248689945 21.8295360053219 14.4284099192971 1.5129550745662 0.13236752088433 -72.1422431848789 32.9803526979555 -2.18743091820698 0.0302389747675556 THRIL other 1 1 1 1.5129550745662 -2.18743091820698 0.00116308482146003 10.7014862011161 6.61476563589918 1.61781789260042 0.107735059756109 -58.9788390505149 21.2745259598799 -2.77227512198104 0.00624926842295269 CCDC163 other 1 1 1 1.61781789260042 -2.77227512198104 0.0623886064599709 -16.890834548016 9.47766717320469 -1.78217215685416 0.0766788999683595 -37.5630164433112 16.2088270623791 -2.31744199001885 0.0217879915326036 SH3PXD2A-AS1 other 1 1 1 -1.78217215685416 -2.31744199001885 1.84224000470138e-05 6.24855804674966 1.83106301159381 3.41253032101322 0.000818767400915965 -6.27467666554356 3.96715620680284 -1.58165606254269 0.115740573258613 EIF1B-AS1 other 0.14793187237752 1 1 3.41253032101322 -1.58165606254269 2.82157674251532e-06 145.498545395304 36.3502172063122 4.00268709728749 9.78709215547951e-05 -98.3571578187911 77.6980551229245 -1.2658895729524 0.207502216375899 PAGR1 other 0.0246267218086737 1 0.896791254206587 4.00268709728749 -1.2658895729524 0.00494038031186999 30.8381181186874 14.1839244430482 2.17415978507991 0.031210137119772 -25.2894327203974 23.0712887600079 -1.09614304530029 0.274716350318143 LINC00294 other 1 1 1 2.17415978507991 -1.09614304530029 1.76070813221123e-13 314.858588881678 48.9544116324891 6.4316693507704 1.95316368598457e-09 -80.7063688087154 87.9519308345987 -0.917619068084938 0.360430935137677 CTBP1-AS other 2.28293416422508e-09 1 2.4426265056923e-05 6.4316693507704 -0.917619068084938 0.0171727193989392 1.92045374929142 2.29741988207673 0.835917615353552 0.404513371384178 -9.49712107411959 4.88846575014167 -1.94276109510317 0.0538932213184446 LINC00921 other 1 1 1 0.835917615353552 -1.94276109510317 7.9602305179692e-05 11.9122586024088 3.36479711204337 3.54026058800756 0.000528050110474776 -2.33726789128836 5.66736600438445 -0.412408143303286 0.680610135891943 N4BP2L2-IT2 other 0.59184313901101 1 1 3.54026058800756 -0.412408143303286 0.138102147779798 -2.74770725837329 2.32268635645131 -1.18298678198263 0.238625719758009 4.15617991868289 5.34952239008219 0.776925417937924 0.438386842186815 TRG-AS1 other 1 1 1 -1.18298678198263 0.776925417937924 0.00358607296773304 10.5956324934698 4.45602190405974 2.37782325168027 0.0186837765463808 -10.4357082596492 7.7895081144205 -1.33971338194384 0.182378264261243 NPTN-IT1 other 1 1 1 2.37782325168027 -1.33971338194384 4.02756415129729e-14 24.5711303687773 2.97347616029135 8.26343614147886 6.69401713070646e-14 -22.8349421215763 20.7997261047475 -1.09784821235527 0.274018315378172 SLFNL1-AS1 other 5.30913506424009e-10 1 9.21966979412201e-10 8.26343614147886 -1.09784821235527 0.0384938984024501 3.9013482534872 2.21523623014265 1.76114321371314 0.0805297071695398 -4.70085868593854 4.76880514221933 -0.985751890829164 0.326058296211079 RASSF1-AS1 other 1 1 1 1.76114321371314 -0.985751890829164 0.439406305862881 -0.601661915026768 1.90401768146522 -0.315995970459562 0.752436227901811 -6.97935209651624 5.54741335868279 -1.25812728297814 0.210262364773395 PANDAR other 1 1 1 -0.315995970459562 -1.25812728297814 5.51844445859911e-06 111.503468705271 22.6445249304805 4.92408072360056 2.12747880909484e-06 44.5693027055572 69.3094676004738 0.643047829518351 0.521131133151317 TGFB2-OT1 other 0.0467136323420415 1 0.0227810430877875 4.92408072360056 0.643047829518351 0.626299627865358 3.42229881612469 5.88988074261078 0.581047217368225 0.562230345396117 -1.97989410060439 9.25610634763402 -0.213901399383822 0.830964306364475 DBET other 1 1 1 0.581047217368225 -0.213901399383822 1.41679832029482e-20 469.184617879585 52.6388111308172 8.91328295226072 1.69638987426276e-15 -208.357778228258 121.516333068311 -1.71464833547215 0.0885028807048249 EBLN3P other 2.00802825935385e-16 1 2.37477618498044e-11 8.91328295226072 -1.71464833547215 0.000207502612527582 26.9222217117656 8.6309405092288 3.11926859917276 0.00221069819143487 -23.6864519685762 18.5500177153155 -1.27689646080607 0.20379880310405 RBM5-AS1 other 1 1 1 3.11926859917276 -1.27689646080607 0.748504484989204 -0.367058875914198 11.2427847132418 -0.0326483949729887 0.973997529126635 26.2793071588392 36.4831221563449 0.720314096096868 0.472430651045755 GIMAP1-GIMAP5 other 1 1 1 -0.0326483949729887 0.720314096096868 0.231789149405211 3.89980529285544 2.85970920304839 1.3637069421948 0.175016545503957 -2.16832233966463 5.87558794984304 -0.369039210743591 0.712698865818645 LINC02246 other 1 1 1 1.3637069421948 -0.369039210743591 0.0203626658528877 -1.20107329228642 79.1331473226933 -0.0151778784608253 0.987909788999926 -428.337925042742 168.795123080717 -2.53762026547362 0.0121483182810598 TMEM265 other 1 1 1 -0.0151778784608253 -2.53762026547362 0.0235782639351009 12.102074559792 4.44906077762915 2.72014143314109 0.00730702791448556 2.91219863768687 23.6025977307729 0.123384665997589 0.901969901436317 PEG13 other 1 1 1 2.72014143314109 0.123384665997589 0.243977536359588 4.70953910086888 14.3994088908921 0.327064752209917 0.744063045443463 -68.7611824707216 46.5833940745895 -1.47608785999193 0.141962108290203 ADORA3 other 1 1 1 0.327064752209917 -1.47608785999193 0.00167678078643386 55.6315430039745 16.5208871602054 3.36734598236205 0.000962923013900712 -53.8526923645055 120.628473608831 -0.446434334725456 0.655923100030755 BISPR other 1 1 1 3.36734598236205 -0.446434334725456 9.75377710195532e-14 169.759939984996 25.6380910430884 6.62139547362127 6.79967514402631e-10 -216.264051012753 68.6284017209712 -3.15123251583269 0.00198334762217961 PCBP2-OT1 other 1.27277037403415e-09 1 8.62538792019738e-06 6.62139547362127 -3.15123251583269 1.71340505509941e-06 93.2014747744968 20.6516844118053 4.51302048375383 1.25682587030454e-05 20.8270089515383 30.5454136328043 0.68183751583482 0.496359265360541 GTF2IP12 other 0.0153007071420377 1 0.126436682552637 4.51302048375383 0.68183751583482 0.0256706486092252 19.4966982475532 9.20769050129281 2.11743631530793 0.0358503783684384 63.2038051730283 37.543221859762 1.68349443766756 0.0943320956187167 IQCJ-SCHIP1 other 1 1 1 2.11743631530793 1.68349443766756 2.52393501034785e-08 7.71732612921291 1.25405037929064 6.15392033418804 6.26005176130677e-09 8.43244489836259 5.22704886400234 1.61323246018134 0.108741318152559 ARL17A other 0.000262211608225039 1 7.68859557323697e-05 6.15392033418804 1.61323246018134 0.0944415639772025 4.03051221491689 1.84218587136485 2.18789660563987 0.030224846362924 1.88821610843114 7.81290935995051 0.241678998365227 0.8093589823649 TXNRD3NB other 1 1 1 2.18789660563987 0.241678998365227 0.448768340300312 -0.103607786791892 1.8397251022242 -0.0563169935913967 0.955161811848406 9.43567369300226 7.92187144125949 1.19109149434797 0.235438433457049 MIR1244-3 other 1 1 1 -0.0563169935913967 1.19109149434797 0.266682140045239 -0.69555650381216 1.60600953805292 -0.433096122614212 0.665543157805067 9.37506233644715 7.06068484352723 1.3277837127997 0.186189166914433 MIR1244-4 other 1 1 1 -0.433096122614212 1.3277837127997 0.234380241291767 -133.555283846015 78.0439787490365 -1.71128235626587 0.0890423247524437 -111.032699355782 114.102569299542 -0.97309552306661 0.332031807835221 MIR1244-2 other 1 1 1 -1.71128235626587 -0.97309552306661 0.321925095229433 3.68561209145988 29.1998405531963 0.12622028140001 0.899721135727858 91.0673621246297 63.979675800028 1.423379549613 0.1566359075022 LINC02009 other 1 1 1 0.12622028140001 1.423379549613 0.509111789651549 1.79079025968486 14.9324155649134 0.119926361003016 0.904693840518159 35.0479112789822 31.6474386681334 1.10744858838364 0.269783135210152 WDFY4 other 1 1 1 0.119926361003016 1.10744858838364